LOCUS       DAPBCF010000001       129435 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.001, whole genome shotgun sequence.
ACCESSION   DAPBCF010000001 DAPBCF010000000
VERSION     DAPBCF010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 129435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 129435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..129435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.001"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..196)
                     /locus_tag="RD508_000001"
     rRNA            complement(<1..196)
                     /locus_tag="RD508_000001"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(877..2373)
                     /gene="lysS"
                     /locus_tag="RD508_000002"
     CDS             complement(877..2373)
                     /gene="lysS"
                     /locus_tag="RD508_000002"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDT7734641.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2484..3488)
                     /gene="dusB"
                     /locus_tag="RD508_000003"
     CDS             complement(2484..3488)
                     /gene="dusB"
                     /locus_tag="RD508_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDT7734642.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3489..4376)
                     /gene="hslO"
                     /locus_tag="RD508_000004"
     CDS             complement(3489..4376)
                     /gene="hslO"
                     /locus_tag="RD508_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDT7734643.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4593..6704)
                     /gene="ftsH"
                     /locus_tag="RD508_000005"
     CDS             complement(4593..6704)
                     /gene="ftsH"
                     /locus_tag="RD508_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDT7734644.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6794..7339)
                     /gene="hpt"
                     /locus_tag="RD508_000006"
     CDS             complement(6794..7339)
                     /gene="hpt"
                     /locus_tag="RD508_000006"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDT7734645.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(7339..8784)
                     /gene="tilS"
                     /locus_tag="RD508_000007"
     CDS             complement(7339..8784)
                     /gene="tilS"
                     /locus_tag="RD508_000007"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDT7734646.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8904..9374)
                     /locus_tag="RD508_000008"
     CDS             complement(8904..9374)
                     /locus_tag="RD508_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HDT7734647.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9420..9845)
                     /locus_tag="RD508_000009"
     CDS             complement(9420..9845)
                     /locus_tag="RD508_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HDT7734648.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9912..10181)
                     /locus_tag="RD508_000010"
     CDS             complement(9912..10181)
                     /locus_tag="RD508_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HDT7734649.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(10192..11787)
                     /locus_tag="RD508_000011"
     CDS             complement(10192..11787)
                     /locus_tag="RD508_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7734650.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11802..15323)
                     /gene="mfd"
                     /locus_tag="RD508_000012"
     CDS             complement(11802..15323)
                     /gene="mfd"
                     /locus_tag="RD508_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDT7734651.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(15340..15900)
                     /locus_tag="RD508_000013"
     CDS             complement(15340..15900)
                     /locus_tag="RD508_000013"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDT7734652.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            16253..17227
                     /locus_tag="RD508_000014"
     CDS             16253..17227
                     /locus_tag="RD508_000014"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDT7734653.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17397..18797
                     /locus_tag="RD508_000015"
     CDS             17397..18797
                     /locus_tag="RD508_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HDT7734654.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18875..19597)
                     /locus_tag="RD508_000016"
     CDS             complement(18875..19597)
                     /locus_tag="RD508_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7734655.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19676..20182)
                     /locus_tag="RD508_000017"
     CDS             complement(19676..20182)
                     /locus_tag="RD508_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDT7734656.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            20305..22104
                     /locus_tag="RD508_000018"
     CDS             20305..22104
                     /locus_tag="RD508_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HDT7734657.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(22172..23746)
                     /locus_tag="RD508_000019"
     CDS             complement(22172..23746)
                     /locus_tag="RD508_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDT7734658.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(24001..24510)
                     /gene="mreD"
                     /locus_tag="RD508_000020"
     CDS             complement(24001..24510)
                     /gene="mreD"
                     /locus_tag="RD508_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDT7734659.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24514..25368)
                     /gene="mreC"
                     /locus_tag="RD508_000021"
     CDS             complement(24514..25368)
                     /gene="mreC"
                     /locus_tag="RD508_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDT7734660.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25523..26161)
                     /locus_tag="RD508_000022"
     CDS             complement(25523..26161)
                     /locus_tag="RD508_000022"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDT7734661.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(26162..26812)
                     /locus_tag="RD508_000023"
     CDS             complement(26162..26812)
                     /locus_tag="RD508_000023"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDT7734662.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26825..27724)
                     /gene="rsgA"
                     /locus_tag="RD508_000024"
     CDS             complement(26825..27724)
                     /gene="rsgA"
                     /locus_tag="RD508_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDT7734663.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27889..29958)
                     /gene="pknB"
                     /locus_tag="RD508_000025"
     CDS             complement(27889..29958)
                     /gene="pknB"
                     /locus_tag="RD508_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HDT7734664.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29955..30695)
                     /locus_tag="RD508_000026"
     CDS             complement(29955..30695)
                     /locus_tag="RD508_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HDT7734665.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30708..32066)
                     /gene="rsmB"
                     /locus_tag="RD508_000027"
     CDS             complement(30708..32066)
                     /gene="rsmB"
                     /locus_tag="RD508_000027"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDT7734666.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(32066..33004)
                     /locus_tag="RD508_000028"
     CDS             complement(32066..33004)
                     /locus_tag="RD508_000028"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDT7734667.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32997..33488)
                     /gene="def"
                     /locus_tag="RD508_000029"
     CDS             complement(32997..33488)
                     /gene="def"
                     /locus_tag="RD508_000029"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDT7734668.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(33503..35911)
                     /gene="priA"
                     /locus_tag="RD508_000030"
     CDS             complement(33503..35911)
                     /gene="priA"
                     /locus_tag="RD508_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDT7734669.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(36164..36469)
                     /locus_tag="RD508_000031"
     CDS             complement(36164..36469)
                     /locus_tag="RD508_000031"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDT7734670.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(36474..37088)
                     /gene="gmk"
                     /locus_tag="RD508_000032"
     CDS             complement(36474..37088)
                     /gene="gmk"
                     /locus_tag="RD508_000032"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDT7734671.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(37575..37859)
                     /locus_tag="RD508_000033"
     CDS             complement(37575..37859)
                     /locus_tag="RD508_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734672.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37877..38767)
                     /locus_tag="RD508_000034"
     CDS             complement(37877..38767)
                     /locus_tag="RD508_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDT7734673.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38787..39005)
                     /locus_tag="RD508_000035"
     CDS             complement(38787..39005)
                     /locus_tag="RD508_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HDT7734674.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38975..40675)
                     /locus_tag="RD508_000036"
     CDS             complement(38975..40675)
                     /locus_tag="RD508_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDT7734675.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40942..41715
                     /locus_tag="RD508_000037"
     CDS             40942..41715
                     /locus_tag="RD508_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734676.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41796..42365)
                     /gene="thiT"
                     /locus_tag="RD508_000038"
     CDS             complement(41796..42365)
                     /gene="thiT"
                     /locus_tag="RD508_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HDT7734677.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(42431..42533)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(42539..43510)
                     /locus_tag="RD508_000039"
     CDS             complement(42539..43510)
                     /locus_tag="RD508_000039"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDT7734678.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(43604..44977)
                     /gene="glmU"
                     /locus_tag="RD508_000040"
     CDS             complement(43604..44977)
                     /gene="glmU"
                     /locus_tag="RD508_000040"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDT7734679.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(45480..46298)
                     /gene="purR"
                     /locus_tag="RD508_000041"
     CDS             complement(45480..46298)
                     /gene="purR"
                     /locus_tag="RD508_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HDT7734680.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(46465..47289)
                     /locus_tag="RD508_000042"
     CDS             complement(46465..47289)
                     /locus_tag="RD508_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDT7734681.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(47262..47942)
                     /locus_tag="RD508_000043"
     CDS             complement(47262..47942)
                     /locus_tag="RD508_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDT7734682.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47965..48903)
                     /locus_tag="RD508_000044"
     CDS             complement(47965..48903)
                     /locus_tag="RD508_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HDT7734683.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(49148..50011)
                     /locus_tag="RD508_000045"
     CDS             complement(49148..50011)
                     /locus_tag="RD508_000045"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDT7734684.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(50153..52726)
                     /gene="mprF"
                     /locus_tag="RD508_000046"
     CDS             complement(50153..52726)
                     /gene="mprF"
                     /locus_tag="RD508_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HDT7734685.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52867..53673
                     /gene="proC"
                     /locus_tag="RD508_000047"
     CDS             52867..53673
                     /gene="proC"
                     /locus_tag="RD508_000047"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDT7734686.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(53752..55308)
                     /gene="rny"
                     /locus_tag="RD508_000048"
     CDS             complement(53752..55308)
                     /gene="rny"
                     /locus_tag="RD508_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HDT7734687.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(55719..56768)
                     /gene="recA"
                     /locus_tag="RD508_000049"
     CDS             complement(55719..56768)
                     /gene="recA"
                     /locus_tag="RD508_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDT7734688.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56877..58118)
                     /locus_tag="RD508_000050"
     CDS             complement(56877..58118)
                     /locus_tag="RD508_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HDT7734689.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(58358..58936)
                     /gene="pgsA"
                     /locus_tag="RD508_000051"
     CDS             complement(58358..58936)
                     /gene="pgsA"
                     /locus_tag="RD508_000051"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDT7734690.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(59145..60068)
                     /locus_tag="RD508_000052"
     CDS             complement(59145..60068)
                     /locus_tag="RD508_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7734691.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(60807..62093)
                     /locus_tag="RD508_000053"
     CDS             complement(60807..62093)
                     /locus_tag="RD508_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDT7734692.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(62086..63354)
                     /locus_tag="RD508_000054"
     CDS             complement(62086..63354)
                     /locus_tag="RD508_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDT7734693.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            63606..64067
                     /gene="mscL"
                     /locus_tag="RD508_000055"
     CDS             63606..64067
                     /gene="mscL"
                     /locus_tag="RD508_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HDT7734694.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(64126..64572)
                     /locus_tag="RD508_000056"
     CDS             complement(64126..64572)
                     /locus_tag="RD508_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7734695.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(64665..64910)
                     /locus_tag="RD508_000057"
     CDS             complement(64665..64910)
                     /locus_tag="RD508_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HDT7734696.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(65025..65603)
                     /locus_tag="RD508_000058"
     CDS             complement(65025..65603)
                     /locus_tag="RD508_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7734697.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(65680..66210)
                     /locus_tag="RD508_000059"
     CDS             complement(65680..66210)
                     /locus_tag="RD508_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HDT7734698.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(66214..67074)
                     /gene="rlmB"
                     /locus_tag="RD508_000060"
     CDS             complement(66214..67074)
                     /gene="rlmB"
                     /locus_tag="RD508_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDT7734699.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(67067..67462)
                     /locus_tag="RD508_000061"
     CDS             complement(67067..67462)
                     /locus_tag="RD508_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HDT7734700.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(67459..68871)
                     /locus_tag="RD508_000062"
     CDS             complement(67459..68871)
                     /locus_tag="RD508_000062"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDT7734701.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68868..69404)
                     /gene="cysE"
                     /locus_tag="RD508_000063"
     CDS             complement(68868..69404)
                     /gene="cysE"
                     /locus_tag="RD508_000063"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDT7734702.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(69490..69729)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(69726..71186)
                     /locus_tag="RD508_000064"
     CDS             complement(69726..71186)
                     /locus_tag="RD508_000064"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDT7734703.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(71356..72513)
                     /locus_tag="RD508_000065"
     CDS             complement(71356..72513)
                     /locus_tag="RD508_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HDT7734704.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(72547..73917)
                     /gene="radA"
                     /locus_tag="RD508_000066"
     CDS             complement(72547..73917)
                     /gene="radA"
                     /locus_tag="RD508_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDT7734705.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73980..74507)
                     /locus_tag="RD508_000067"
     CDS             complement(73980..74507)
                     /locus_tag="RD508_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDT7734706.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            74737..75543
                     /gene="proB"
                     /locus_tag="RD508_000068"
     CDS             74737..75543
                     /gene="proB"
                     /locus_tag="RD508_000068"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HDT7734707.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            75540..76787
                     /locus_tag="RD508_000069"
     CDS             75540..76787
                     /locus_tag="RD508_000069"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HDT7734708.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            76863..77207
                     /locus_tag="RD508_000070"
     CDS             76863..77207
                     /locus_tag="RD508_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734709.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(77324..77650)
                     /locus_tag="RD508_000071"
     CDS             complement(77324..77650)
                     /locus_tag="RD508_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734710.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(78265..79467)
                     /locus_tag="RD508_000072"
     CDS             complement(78265..79467)
                     /locus_tag="RD508_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7734711.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            79584..80099
                     /locus_tag="RD508_000073"
     CDS             79584..80099
                     /locus_tag="RD508_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7734712.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(80298..80744)
                     /locus_tag="RD508_000074"
     CDS             complement(80298..80744)
                     /locus_tag="RD508_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HDT7734713.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(80791..82269)
                     /gene="msr(C)"
                     /locus_tag="RD508_000075"
     CDS             complement(80791..82269)
                     /gene="msr(C)"
                     /locus_tag="RD508_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HDT7734714.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(82623..83252)
                     /locus_tag="RD508_000076"
     CDS             complement(82623..83252)
                     /locus_tag="RD508_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDT7734715.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(83236..83700)
                     /locus_tag="RD508_000077"
     CDS             complement(83236..83700)
                     /locus_tag="RD508_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7734716.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(84187..85455)
                     /locus_tag="RD508_000078"
     CDS             complement(84187..85455)
                     /locus_tag="RD508_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HDT7734717.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(85686..86423)
                     /locus_tag="RD508_000079"
     CDS             complement(85686..86423)
                     /locus_tag="RD508_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7734718.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(86490..87059)
                     /locus_tag="RD508_000080"
     CDS             complement(86490..87059)
                     /locus_tag="RD508_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDT7734719.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            87187..88059
                     /locus_tag="RD508_000081"
     CDS             87187..88059
                     /locus_tag="RD508_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7734720.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            88401..89273
                     /locus_tag="RD508_000082"
     CDS             88401..89273
                     /locus_tag="RD508_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7734721.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            89270..91228
                     /locus_tag="RD508_000083"
     CDS             89270..91228
                     /locus_tag="RD508_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7734722.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(91560..92411)
                     /locus_tag="RD508_000084"
     CDS             complement(91560..92411)
                     /locus_tag="RD508_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7734723.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            92534..93001
                     /locus_tag="RD508_000085"
     CDS             92534..93001
                     /locus_tag="RD508_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDT7734724.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(93264..93746)
                     /locus_tag="RD508_000086"
     CDS             complement(93264..93746)
                     /locus_tag="RD508_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDT7734725.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(93846..94709)
                     /locus_tag="RD508_000087"
     CDS             complement(93846..94709)
                     /locus_tag="RD508_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDT7734726.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            95307..96182
                     /locus_tag="RD508_000088"
     CDS             95307..96182
                     /locus_tag="RD508_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734727.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(96327..96479)
                     /locus_tag="RD508_000089"
                     /pseudo
     CDS             complement(96327..96479)
                     /locus_tag="RD508_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(96747..98078)
                     /locus_tag="RD508_000090"
     CDS             complement(96747..98078)
                     /locus_tag="RD508_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7734728.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(98227..98940)
                     /locus_tag="RD508_000091"
     CDS             complement(98227..98940)
                     /locus_tag="RD508_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7734729.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            99115..100539
                     /locus_tag="RD508_000092"
     CDS             99115..100539
                     /locus_tag="RD508_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7734730.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            100838..101545
                     /locus_tag="RD508_000093"
     CDS             100838..101545
                     /locus_tag="RD508_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDT7734731.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            101532..101855
                     /locus_tag="RD508_000094"
     CDS             101532..101855
                     /locus_tag="RD508_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDT7734732.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(101944..102981)
                     /locus_tag="RD508_000095"
     CDS             complement(101944..102981)
                     /locus_tag="RD508_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7734733.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(103302..104285)
                     /locus_tag="RD508_000096"
     CDS             complement(103302..104285)
                     /locus_tag="RD508_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HDT7734734.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(104700..105470)
                     /locus_tag="RD508_000097"
     CDS             complement(104700..105470)
                     /locus_tag="RD508_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7734735.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(105463..106398)
                     /locus_tag="RD508_000098"
     CDS             complement(105463..106398)
                     /locus_tag="RD508_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7734736.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(106714..108363)
                     /locus_tag="RD508_000099"
     CDS             complement(106714..108363)
                     /locus_tag="RD508_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDT7734737.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(108480..111083)
                     /locus_tag="RD508_000100"
     CDS             complement(108480..111083)
                     /locus_tag="RD508_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDT7734738.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(111095..112144)
                     /locus_tag="RD508_000101"
     CDS             complement(111095..112144)
                     /locus_tag="RD508_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDT7734739.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(112170..112484)
                     /locus_tag="RD508_000102"
     CDS             complement(112170..112484)
                     /locus_tag="RD508_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDT7734740.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(112500..112946)
                     /locus_tag="RD508_000103"
     CDS             complement(112500..112946)
                     /locus_tag="RD508_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7734741.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(112947..114869)
                     /locus_tag="RD508_000104"
     CDS             complement(112947..114869)
                     /locus_tag="RD508_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDT7734742.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(115081..115977)
                     /locus_tag="RD508_000105"
     CDS             complement(115081..115977)
                     /locus_tag="RD508_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7734743.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(115970..116650)
                     /locus_tag="RD508_000106"
     CDS             complement(115970..116650)
                     /locus_tag="RD508_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7734744.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(116651..117433)
                     /locus_tag="RD508_000107"
     CDS             complement(116651..117433)
                     /locus_tag="RD508_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7734745.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(117426..118343)
                     /locus_tag="RD508_000108"
     CDS             complement(117426..118343)
                     /locus_tag="RD508_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7734746.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(118507..118830)
                     /locus_tag="RD508_000109"
     CDS             complement(118507..118830)
                     /locus_tag="RD508_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734747.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            119618..122845
                     /gene="fss3"
                     /locus_tag="RD508_000110"
     CDS             119618..122845
                     /gene="fss3"
                     /locus_tag="RD508_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HDT7734748.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            122958..123272
                     /locus_tag="RD508_000111"
     CDS             122958..123272
                     /locus_tag="RD508_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7734749.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            123285..123659
                     /locus_tag="RD508_000112"
     CDS             123285..123659
                     /locus_tag="RD508_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7734750.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            123669..124004
                     /locus_tag="RD508_000113"
     CDS             123669..124004
                     /locus_tag="RD508_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HDT7734751.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            124087..125427
                     /locus_tag="RD508_000114"
     CDS             124087..125427
                     /locus_tag="RD508_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HDT7734752.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            125505..126179
                     /locus_tag="RD508_000115"
     CDS             125505..126179
                     /locus_tag="RD508_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HDT7734753.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            126172..126336
                     /locus_tag="RD508_000116"
     CDS             126172..126336
                     /locus_tag="RD508_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734754.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            126412..127554
                     /gene="dcm"
                     /locus_tag="RD508_000117"
                     /pseudo
     CDS             126412..127554
                     /gene="dcm"
                     /locus_tag="RD508_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            127544..127834
                     /locus_tag="RD508_000118"
     CDS             127544..127834
                     /locus_tag="RD508_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734755.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            128093..129277
                     /locus_tag="RD508_000119"
     CDS             128093..129277
                     /locus_tag="RD508_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDT7734756.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            129274..129411
                     /locus_tag="RD508_000120"
     CDS             129274..129411
                     /locus_tag="RD508_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HDT7734757.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
BASE COUNT        37237 a        27076 c        23328 g        41794 t
ORIGIN      
        1 gattgttata cggtattagc acctgtttcc aagtgttatc cccttctgat gggcaggtta
       61 cccacgtgtt actcacccgt tcgccactcc tctttttccg gtggagcaag ctccggtgga
      121 aaaagaagcg ttcgacttgc atgtattagg cacgccgcca gcgttcgtcc tgagccagga
      181 tcaaactctc ataaaaagtt cgaacaatct tgcgattgtt aagctcaatt tgtttgctag
      241 catattgctt gcttgttaaa aatgtttgtt gtcttgaatt gaatcaagac gccctacaca
      301 tttggtttgt cttactttgt tcagttttca aaggtctact tcatcgagag tgtttcccga
      361 ttcatttttg gctgccgtag caacttttat atcatatcag agagacaagc gattgtcaac
      421 tcttttttaa aagttttttt cgatttcgtt tttcgaaatc tttcggcaac tcatttatca
      481 taacttatcg tttgttattt gtcaagaact tttttgaagt ttttttcgat agaatcaagc
      541 ttcgcaagtg gttctttttt aacgactcag ttatcttatc atgtcgttag taacatgtca
      601 ataacttttt tgttatgttt ttgaataaat attttcttct gtcttttgga caagtaataa
      661 tataccaact aaatttagct tggtcaacga attttttgta ttttttcaag tttttttcaa
      721 taaacgatta ttcataactt ttctttcttt atcgttcgtt ttcgtcttct ttaatgtcta
      781 gaatagtcgg cattagcttt tgaactttcg ttattattta ttcctttcta cacagcaaaa
      841 gctgcctaag gaattcctta gacagctttt attcgattat ctcattgttg ggaatagcaa
      901 aacatcccga attgattgtg catcagttag caacattact aatctgtcga tcccgatgcc
      961 tagaccacca gttggcggca taccgtattc taaggcttcc aagaagtctt cgtctacacc
     1021 gtgagcttcg tcatttccta gttcacgttc tttttcttgc gcttcgaatc tttctctttg
     1081 atcaattgga tcgttcagtt ctgtaaaggc attagcaaat tcgcgcccca ctatgaatag
     1141 ttcgaatcga tctgtgaatc gaggatcttc tggatttttc ttcgctaaag gcgaaacttc
     1201 gactggatgt ccgtatacaa acgtcggttg tgtcaatgtt tcttcaacaa atgtttcaaa
     1261 gaattcattg ataacatgtc cgacacccat agcttcggtt acttctacat tgtgtttttc
     1321 ggctaaagct aatgcttctt ccaatgtcat ttcttgccag aagtctacac cagtttgttc
     1381 tttgattgca tctaccatat ggatgcgttt aaagtcactt tctaagtcga cagcttgtcc
     1441 atcatatgtg atttttgctg ttcctagtac tttttcagct gcgttacgga taataccttc
     1501 tgtcagattc attacatcat tgaaatcagt atatgctgtg tatgcttcta acatcgtaaa
     1561 ttctggatta tgtgtagtat caattccttc attacggaaa acgcggccga tttcataaac
     1621 tttttccatt ccgccaacaa ttagtcgttt taaatgaagt tctagcgcaa tacgcaaata
     1681 taaatcaatg tccagtgcat tatgatgcgt gataaatggg cgtgcggcag ctccacctgc
     1741 ctcattgtgc aatactggtg tttctacttc aatatagcca ttgccatcta aatagcgacg
     1801 gatttcgctg ataatttggc ttcgtttcat aaatcggtca aagctttcgc gattactgat
     1861 taaatccaag tagcgttgtc tgtagcgttg ttcaatattc gttaagccat ggtatttatc
     1921 tggcagtgga cgaagtgctt ttgacaaaat cgtgatttct gaagctttga tagaaacttc
     1981 gcctgtgtct gttttcatga tttgtccagt tacaccaaag aaatctccaa ggtctgcatg
     2041 tttgaatact tcataggcct catcacctac ttggtctttt cttacataaa tttgaatttg
     2101 gccttcacga tcttgtagat gcgcaaatcc agctttccct tttcctcggc gagtcatcat
     2161 acgaccagct acactagcgg tcaatcccat ttctgctagt tcttcttttg ttcttggatc
     2221 aaatagttca tgcaattctt ctgagttgtg cgtgcgttca aatcgttttc caaatggatc
     2281 gattccatct tcacgcaatt gttccatttt ttgacgacgt acaagcattt gatcatttaa
     2341 atcttctact tgatgttgtt gttcctgtgt cacaaaagtt cctccattct catgttaatc
     2401 tctttcctat aatgccaatg aaacacaaaa aaagcaagcc gaacttggaa tttcggcttg
     2461 aaaattcacg aaaaacttag aaatcacaac gtttgtttca atagtacttt ttccgctttt
     2521 tctacaaatt gatccagcag gtcattgatt tcttgctgtt tttctgtctg attgattgct
     2581 actttcactt tcgctgctcg aggaatccct tttaaataat aagccgcatg tgttctgaat
     2641 tctctacaag ctactttttc tcctttgaga tctgctaagc gttgtaaatg aagtttagct
     2701 gtagcaattt tttcggctgg tgttggttca ggaatcagtt cccctgtttc gagataatgc
     2761 tgtgtgcggt gaatcatcca tggattgccc agcgctgcac gaccaatcat cacaccgtct
     2821 gcaccgacat agtcaagcat ccattttgca tcttctggcg ttttgacatc cccgttcccc
     2881 ataaatggaa tcgtcaaatg ttttttcact tctttcaata cttcccagtc cgcttttcct
     2941 tcatacatct gaacccgtgt acgtccatgc atagcgatgg cacttgctcc agctgattgt
     3001 gctgctaatg cattttctac agcaaagacg tgctcttcat cccaaccaat acgcatcttg
     3061 attgttactg ggatatttac tgctgaagaa acagcttgga ccatttcgta tactttctca
     3121 ggatctaaaa gccattttgc tcctgcttct gctttgatta ctttatttac tggacagccc
     3181 atattgatat ctattatatc ggcagctgtg ttttcttcga caaattgagc agcttcaact
     3241 agactatctt tatttccgcc aaatatctgt aaacttaatg gatgttctgt ttcttcaatg
     3301 tggagcatct ctaaagtttt tttgtttctg aaatgaatac cttggtcact gatcatttca
     3361 catacgacta agcccgcacc aaattctttg acagtgactc gaaatgctga atttgttatt
     3421 ccagccatcg gtgcaacaac gacacgatta gggatttcca cattgccaat tttccatgtg
     3481 tgttccactt aaatccctcc taaggcttct ttcttcaatc catctaattc ttcttcgcta
     3541 tacttgtatt tgttattaca gaaagaacaa accgcttctg caccgtgatc ttcgtctatc
     3601 attgcttgga tttcttctgc acctaacgcg ataattgctt ctgcaaattt ttcttttgaa
     3661 cagtcacatt tgaattgaac aggcattttt tccaaaatgt tcaattcttc tgtaccaagc
     3721 aatcctttca atatttcttc tggtgtctgt ccttcatcta agagggtaga gattcttggt
     3781 gtcgttttta attgttcttc gatcttgctg attgtttctt catcggcacc tggcatgatt
     3841 tggatcatga atcctcccgc cgtcttgatg ctgtcgtcag tattgaccaa tacactcagt
     3901 ccaacagctg aagggatttg ttctgagata gcaagatagt aagtaaaatc ttcagcgatt
     3961 tctccagaaa caatcggcgt ttgcccagaa aaaggttctt ttaatcctaa gtcttttgtg
     4021 acagtaaaca ttccttgtgt tccaactgct ccccgcacat cgattttacc ttcactattt
     4081 agaggaagac tgagatgcgg atttttgatg taacctttca catctccctt tccatttgca
     4141 tctactacaa ttcctgttgc tggaccatcg ccttggattc gaacagttag tttgtcttct
     4201 cctttgagcg tcgcaccaag tagcagacta ccgaccaatg tccgtcccaa agcagctgag
     4261 gaggtgtgcc aagtatcatg acgtctttgt gcctccgcta cggtatttgt tgcttgaacg
     4321 gcgtatgctc ggacgaatcc gtcgtgagca agtgccttaa ccaaataatc tttcatttgt
     4381 tatgtactcc tttttccgtt tttaaactca tagtgaatca tactagcaac tactgctttt
     4441 ttcaactttg gaatgcttct tttaaaaata attcagaatc atctagaaaa caggacatca
     4501 ccctatttac aacttaaata aagaaatctc ccgaaaaccg gtttttgttc cggttttcgg
     4561 gagtcatatc agatcaattg acctatattt ttttatttgt attgatcgtc tgaatgatta
     4621 tcttctgatt gttgagaatc tgaatcatgt tctgctttat tttcctcatt cagttcatgt
     4681 tttgcttctt caaaatcacg tttttcttcc gcttgttttt cagcgtcttt ttcttccaaa
     4741 gcacgttttg cttcttcaaa agttttcgct tctttttcgc ttggataatc atttgactca
     4801 gtaccttcag gcatcacacc gtgttcaaac aatgacttga ttgctttggc atccaatgtt
     4861 tcgaattcca aaagtttttc agcaatcagt ttatgctgtg cacgatgagc ttcgatgatt
     4921 tctcgagctt tatcatgagc ttccatcaag atttttcgta cttcttgatc aatctcgaaa
     4981 gcgacttgtt ccgagtaagc ttttgtttga ccatagtcgc ggccaacaaa cacttgatgg
     5041 tttccttcat attgaacagg acctaaacga tcactcattc catattctgt taccatgctt
     5101 cgtgctagag ctgtcgcttg ctcaaagtca ttggaagcac cagttgattg gacattgaag
     5161 atgatttctt cagctgtacg tccaccaagt aagcctacga tttgttcaaa catatcttct
     5221 ttcgtcatca agaactgatc ttcttttggt aaagcgatca tatatccgcc ggcgcgtccg
     5281 cgagggatga tcgttacttt gtggacgacc cgagcgcgac tcaatactaa tccgacaatc
     5341 gtatgaccag cttcgtgata agcaaccatt tcgcgttctt ttttgctgat tacgcgatct
     5401 tttttagctg gacctgcaat cacgcgatct tccgcttcat cgatatcaga agcatcgatt
     5461 ttctttttat ttcttctagc agctactaac gctgcttcat tcaagacatt ttctaaatct
     5521 gctccggcaa aacctggtgt ctgttgagcc acaactttca agtcaacgtc atctgccatc
     5581 ggtttattcc gtgcatggac tcgcaagatt gcttcacgac cttttacatc tggacgtcca
     5641 actaaaatct ggcggtcaaa acggcctgga cgtagtaacg ctgggtctag tacatcagaa
     5701 cggttggttg cagcaatgac gattactcct tcatttccgt cgaagccatc catttctaca
     5761 agcaattggt tcaatgtttg ttcgcgttca tcatgtccgc cgcccatacc ggcaccacgt
     5821 tgacgaccta ccgcatcaat ttcatcaatg aaaatgatag ctggtgcgtt tttcttcgct
     5881 gtttcaaaca aatcacgaac acgacttgct ccaacaccga caaacatttc tacgaaatca
     5941 gaacccgaga tcgagtaaaa cggtactcca gcttctccgg caacagcttt tgctaataag
     6001 gttttacctg ttcctggagg tccttctaaa agtacacctg ccgggatacg ggcacctaat
     6061 tcaacaaatc ggcgaggatc tttcagaaat tcaacaactt caactagttc ttgtttttct
     6121 tcttccgcac ccgctacatc agaaaaacgt acgcgattag cttttttgtc tgcttctttg
     6181 gcttttgatt taccaaagtt catgacacgg ccgccaccgc caccgccgcc gccttgttgt
     6241 cccatcatca tgtaaaagaa aaagatgatg attacgattg gcaagaagct aagcaatagg
     6301 gaaacccata taccgctgct tgattcttct tttactgttg tagcaacttt gttttctttt
     6361 gccagttctg ttacttggct caatgttgta tcatttggca aaatgattgt tgtgaaatgg
     6421 gtagtagtcg tatctgttga acctaagata gctaacccac cgctgttagc gacggtctgc
     6481 tgttctttgt attcaccagt gatcttatat acaccatttg caggctgcac ttcaaattct
     6541 ttgatcttgc ctgcttgtag ttgttctgtg aattttgagt actcgatatc tgacgatcgc
     6601 tggccgttat taccaaaaat gaaataaacg accattacca tcgctaagat tacgaggaca
     6661 taatacaagg catttttcat catgccgttg ttctttttgt tcatagttgc cctccctaag
     6721 cgtcaattta atttaacagt tttttatcaa tcctgaccat tctattgtac cataatttaa
     6781 ttgagataca gcattaattt gattgataaa cactaggttt caatacaccg atgtacggaa
     6841 ggttacgata tgcttctgca taatccaagc cataaccgac cacaaattca tttggtacgt
     6901 tgaagccaac ataatctgct tcgatattta ctactcttcc ttcaggtttg tcaagtagtg
     6961 taacaatttt gactgatttt gctttgcggt atttgaaaag atccactaaa taagcaagtg
     7021 ttcttccgct gtcaatgata tcttcaacga tcaacagatc gcgaccttct acattcgtat
     7081 ctaagtcttt gacgattttt acttcccctg acgagactgt tgcattcccg tagcttgaaa
     7141 catccatgaa atccaattcc aaatacgtat cgatagaacg aacgatatct gccatgaatg
     7201 gtaccgctcc ttttaagaca cctactacta ggggattggt gttttggtaa atttctgtta
     7261 actctttgcc tagttctttg caacgaactt gtatctcttc ttgtgagatc aaaattctct
     7321 caatatcctt ttccaacatc aggttctcct tccaattgct tctttttgat atttgtaaag
     7381 aagtatgtag tgtattttat cagtttcttc acgaatactc aaatatgaaa aggcaaaagg
     7441 tatcaagcta tatatatttc ttttggcatc tgtaatgatc caagcatgct gcctttgtga
     7501 attaggtact ttctgatcga taaaatatct agatactttt tttgtgagat tctctgttaa
     7561 tttaatgcgg tctcctgctt ttcttttttc gacatacagt tgcacatcag caggaatcca
     7621 aatgtcatga gaaaatagag accatgaatc tgttgctttg atgtcccctg cattttcagg
     7681 tttgaccaga ccaatccatt ctgtttcatt caaatatatt ccttgttctg gaatcagcaa
     7741 caagcgctgg tcttctgtct ggctagttgc ttgtttttct tttttagaga gtacaacaaa
     7801 atgatactct cttttcagta tccaattatt gccaatactg agttgccatt ggcttttttt
     7861 ctgttgccac tggtctaaaa tcgactccat ttgttgttct ttcaaaataa ttcctgtttt
     7921 tgagaatgct ttgtcgaaaa aggagtaaaa aaaatagtat cgttcagcat ctgtcatttc
     7981 ttcaatcatt tctgcagaaa atcgaaattg ttcctcccac tgttcgactt ccttttcgat
     8041 caactgtccc atatattttt gaatgacttg gtctgcccat tggatctgtt gcgaaaattg
     8101 ctggaaatgt ctcaacgcct gtgtattttc ttgtttcaat tgaggaacta ccaaatgacg
     8161 aagccgattt ctctggatat ctaacaattg gtttgtctga tcctcaaagt aaacaagctg
     8221 cgattccgct gcataagtat ataggtcttc tttgctaaaa ctcagcaacg gacgaatcag
     8281 tctgcccgta gcaaatggtt gtacttcttt gattccagaa aaagtattta actgtccccc
     8341 acgaacgatt ttcattaaca ccgtctcgat ttgatcatct ccgtgatgag cagtcatcaa
     8401 cgtgtcatat tgtccttctt ccatcacgcg agtgaattct tgataacgaa agttacgagc
     8461 ttctgtttct atggcggatt tggctggatc ttcccaaata cttacatata aagggagatt
     8521 cttctcttca caatatgagc gaagataggc agcttcttct gctgattctt ctcttaattg
     8581 gtgattgatg tggacgatac ctaaagaaaa accgatttgg cgttgcactt gtaaaagtaa
     8641 atggagcaaa accatcgaat caacaccacc tgataccgct gctaaaattc tcgatccttg
     8701 ttgccagaat ccttgttcat tcccgtgccg aataaatgac tgctgtaata gcggtgcttt
     8761 tttcccgcct ttttcaacgt tcatcctttc cacacccttt cttcctaaaa aaaagagagc
     8821 gggaaaacgt ctaaaacgac aattaacctg ccctctgttg atactatgac ccaaatagtc
     8881 gcactatcat tatttgcggc tttttagctg cgacgtccgc cacggccacc gcgctttcct
     8941 tctgtgtttc gcttcaatga agataagcgg tcatcgctat ctttcaaaaa tgaactcatc
     9001 aatgaatcga agtcttcttt ttgagctgaa ggttgactgc gagaaaaaga ttttttctgt
     9061 gctggacgat ttcggttgtc acggggatct ttttgttgat attttttagg acggctttct
     9121 tctccagatt cagcaggttg ttcctgcgct ttccggatag atagtccgat ttttccatca
     9181 tcatttactg aaataacttt aactgttact tcatctccta cacttaaaac atcatggatg
     9241 tcttttacat agccatttga cacttcgcta atatgaacta gacccgtttt tccagcacct
     9301 agatcaataa acgcaccaaa atttgtgatt cctgatactt ttccttgcag ttttgctcct
     9361 acctcgattg acataaaaaa aatgttcctc ctaattattt ccctttttta tattcctgct
     9421 tattttgcag ttgtagaact agttgattga tctgtttcat ttgtcgagct gtctgtattt
     9481 gattctaata taggataaac tttttcaccg tcttttgagt aaaagaattt gcttctggca
     9541 agtttagcta catactcatc atctttcagc aatgaaacat cttggtgcag ctgatcaacg
     9601 tctgcgttga cttctttcat ttcagtattt gcttcgactc tcaattcgtt caattgatgc
     9661 atcctttgca tgtcatggaa aatctgcaca cctattatcg cgaaaatgac caaagcacca
     9721 acaaaaattg cagccagtct gcgtcttcga aaaatcagtt gacgttgttg ttgctgaaat
     9781 tcagcatact ttttctttgc atattccgta tctagcgcag cgattttatt gctttttttc
     9841 gtcacttgga ttcgctccaa tctttttgat tgtctttttc attataccaa tatcgtgaaa
     9901 gcttgtctaa tctatttctc tagtgtttct gtgcgatttt cagaaataat ttcgtacatt
     9961 ttttgtgcat cttctttttt ggttgattca tgtaattccg taattttcac ttccaacgtt
    10021 ttgttgccaa actggacttt caaaatatcg cctactttga catcactgga agatttcgcc
    10081 aatttaccgt tgatttgaat tcttccttta tcagctactt cttttgctac tgatcgtctt
    10141 ttgatgattc gggaaatttt taaaaattta tctaatcgca tatcttattc ctcacttttt
    10201 aattttttta tttaatcgca ggattttctt accaaaaggc aacattagcc attctcgtac
    10261 tgtaaacaga cgaagacgaa tcactgcata aatgaacaca gaagccccga tcccaactcc
    10321 tatcacgctg acaaaaaaag cagtggaacg atgagttaca ggaccaaata ctatattcaa
    10381 tacaccataa tacagcagca gtactactgt catacaaaga aggctgaaca tcaacttccg
    10441 tccaaaatgc cgttctttcc aaaaagcatt tagctctttt gtttcaattc gaacaaaata
    10501 ccaaagcgtc acacctaatc ctaaaagggt agacaggctt gcacctgctg ttcctaataa
    10561 accggtcaga aaagaagtag tcaatccttt taccaatagt ccccatcctg cgccttttaa
    10621 agaagggcga aacgagttct tgctttgagc aatactttga taagcttgga tgactgcagt
    10681 gaaagcaatg gaaaaaacaa ataatacaag cgctgcattt cccgcataat ctttaaacaa
    10741 cgcataattg atataaggga gcagcaaggc taatcccaaa gacgcagcta atgctaaagc
    10801 ggtcgtcaat ctaagataga ttttggctgt ctgtaaaaac tgacgataga tccggttggt
    10861 caaatgacga gtcaacgcag gcaggaatgt cgcacttaat gcagtggcaa tcactaaacc
    10921 taattgtact aaaggctgac ctcgatcata gacccctttt gctatcttcg caccgtattc
    10981 tgacagtccg taaacttcca aagcattttt tacaaagaaa gagtcgatca gctggaaaaa
    11041 gataagcaat ccactataaa tcgaaaccag tccgccttct accagaaaac gccggatcaa
    11101 gggctttgac ggctgtttga acaatggaaa ccgtcggaag cttaacgctc ctccatgaat
    11161 cttttgttca tagtagtgaa ggatcccata tgcgcataaa ccgccaaaaa cagctccact
    11221 cattgctgcc gtccctgttt ggtacaccgt ccatccaagc tttctaaaag caaacgcact
    11281 acagacaatc acaaaaacac gaacgaactg ctcaactact tgagaaacag cagttggttc
    11341 catcaagaat cttccttgga aattccctcg ataaaaagat agaccaggca tcagcaaaaa
    11401 ggtaaaggaa actacttgga tcagcggttt caattgtatg tctcccatca tccaagcaat
    11461 ccagctgcta aatgcaaaga caaacaacca caaaaagaca cctgtccaaa atactaaggg
    11521 ataaagattt tgcaaagctt gctttcgctc gaaaggattc tttctttctg caacgtactt
    11581 tgatatgaac tgcggaagac cggataaagc taaagtcatt gctatcccat aaattggata
    11641 aacttgctga taaacataaa aaccttcgtc gccgactaag ttttggaggg gaattcggta
    11701 aagggcactt aatacttttg ctatgaaaga agcaatcgtc aatacaaatg ctccttgcat
    11761 gacgcgccgc atttctttat gatccaaatc attgctcctt cctacgctga cagatatttt
    11821 tgctcacgca acgctttgac aaacttttgg atttcctgaa gccatactgc ttcttccatt
    11881 tggttgggga tcgtcaagcg tatcaccatc tgttcttttt caacgcctag actggctttt
    11941 agttttgtcg ctgtcagtgc ttcgaataac tgttccacac tatagcgttt tgttccaact
    12001 ttacttagag taaagactat atgcgcctcc tgtttcctta tcgtttctag gagcgctcga
    12061 tcgccatcca ttttgatctg cccaattgtc aagagatgtg ctacttcttc tggatattct
    12121 ccaaaacggt cgagcagatc atcttctagt tcatctagca tttcttgcga atcaagttca
    12181 cgaattcgtt tatagatctc gattttctgc cgttgatctg ccacgtatgt ttcaggtaga
    12241 tacgcatcga caccgaggtc gatctcaaca gtggtcttct ccacttgact attctttcct
    12301 tgtttacgag aaacagcttc gcttagcatt tgagaataca tatcgaaacc gactgcatca
    12361 ataaatccat gctgctgagc acctaagaga ttacctgcac cgcgaatgga aagatcccgc
    12421 atcgcaatct tgaatccaga tcccagttct gtaaaatctt tgattgcctg aagacgtttt
    12481 tcactgactt cgttaaggat cttctgctgc tcatacataa agtaagcata tgcgacacgg
    12541 ctgcttcttc ctacccgccc tcgcaattgg tataacgtgg ataatcccat ataatcagcg
    12601 ttctcaacga acaacgtatt tgcgttcggg atatctactc ctgtttcaat gatggttgta
    12661 gtgacaagaa catcatattg accttcaata aattcaaaaa gcgtattttc taattgcgcc
    12721 tctgtcattt gcccatgagc ataaccgatc cgtgcttccg gaacgagttc ttggatttct
    12781 tctacttttt gttcgatcgt ttctacccga ttatataaat agaatacttg tccacctcgt
    12841 cccatttctc gatggattgc ttcgcgaata gccccaggat ttttttccat aacatacgtt
    12901 tggatcggat aacgattcgc aggcggtgtt tcgattactg aaagatcccg cacgcctaac
    12961 atcgacatat gcaaagttct cggaatcggt gttgcagtca gagtcaaaac atccacttgt
    13021 gcacgtaact gtttcaatcg ttccttatgt tttacaccaa aacgttgttc ttcgtcaatg
    13081 atcagtagac ccaaatcgct aaattcaata tcttttgaca aaattcggtg ggttcctaca
    13141 acaatatcaa cttgacctgt acgcagttgt tcgatggttt ctttttgttg ctttcttgtt
    13201 ctgaaacgac ttaatagccc gatatttacg gggaaacctt caaatctttc cagcatcgtt
    13261 tcatagtgct gctgtgccaa gatcgttgtt ggaactaaaa aggctacttg tttgctttcc
    13321 tttatcgctt taaaggccgc tcgaagcgct acttctgttt tcccataacc aacatcacct
    13381 acgagtagtc gatccattgg tttttctttt tccatatccc gtttgatctc cgctgcactt
    13441 ctcaactggt catcagtttc agagtagggg aaggcatttt cgaattcttt ttggtaggcg
    13501 tcatcaggtc caaaagcata tcctttttct gactctcttg cggcatataa tttgattaga
    13561 tcgtcagcga tatcctcgat ttttgaagag acttttcgct tggttttcgt ccattcactt
    13621 ccgcctagct tattgatgcg aggcgctttg gcttcagagg cgacatattt ttggatcaga
    13681 ttcagttgag taacaggaat aaacagtttg tcgtcgtttt gatacaaaat agtcatatag
    13741 tcttggtgaa cgccatctac ttctagcgtt tccatcccaa tgtatttccc gataccatga
    13801 ttggcatgga caacgtaatc tcctgctttt aactcattat agcttttcaa tcgctctgcg
    13861 tttgttactg tttgacgtct cgtttgtttt ttcgtcgttt tttggaaaat ttctttttct
    13921 gtgatagcta ctattttttc ttgaggaagt tcaaaaccag cctgcaaagc tccttcaact
    13981 aattgtacct gtcctctgat caatgcattt ttttctgttt ctactactaa tatgtcttca
    14041 tctcgaagca tttgttctgc tttgcgtatt ctgtcctttg tcggaataaa gatcacaaca
    14101 gtctgttttt gcttgcgcca acggtccatt tctgttttca gcaatggcat ttgtccgaag
    14161 aactgttgca tcgtccgata ttgaaaatta tggattgctt ggaaacgaag atttcccatc
    14221 cctttttgga agagtgagaa aaaggttgtg gtgaactttt ccttctgcac gattttttgt
    14281 atatctgctg aaaatgtctg ctcagaaaac acccgcaatt cgctgatttt ttgagtctgc
    14341 cattctgccg cttccctttc gatttcccga tttgtttcca tgattcgctg ataatcatca
    14401 acgactagta aactatttga agggaaataa tccaagatcg tcacagattc ttggtaaaga
    14461 agatctgagt agaattttgc ttcttctgtc gggacacctg cttgccagct tgaagtcagc
    14521 tgaccgaagt aatcttgcaa aaactcgcgg tctgcttctt ctgtggtcgc agcaagccgt
    14581 ttttctagca ttttttgcat ttgctctatt ccatgttcta gatcctctgg tccgtagact
    14641 tgttcactcg ttggggaaac ccagatttct tccgtttttt cgattgagcg ttgtgtttct
    14701 gcttcaaaat accgcataga atctatctct acatcaaata gttctacacg aacaggatag
    14761 gttgtcgtta acgggtaaat atcgataatg cttcctcgaa tactgaattc tcccggtttt
    14821 gcgaccatct cttctcgtac atagcccatc aaagtcaatt ggcgaggaag attttccacg
    14881 tctatctcat caccaatatg ccaattcaat tgcgcctgta gccaagtttt cttattcggc
    14941 agtcgtttgt gcaaagatgc gactggcaac aaatagatac ctgctttttt ttcttgaagt
    15001 gcgttaagcg ttgcaactct ctcgcctcgc gcttctggag aagaaaaggc catttcagca
    15061 gaaagcactt catccactgg aaataaatgg atctgatctt gcggaatcac atgttgcaga
    15121 tcttctgcta actgattcgc ataatacaaa tttggcatca gaataatcat gtttttattt
    15181 gttttcttaa acgctcgagc aaatagaagt gttttcgctg agcccgctaa tcctgtgatt
    15241 agttgtctag gcattttttc ttctaaattg ctgacccatt cttttacttg cggatctttt
    15301 ccgactaatt gaataatatc cattcctttt cctccttcct caattgaatc gattcatcgc
    15361 atccacgaac gaatgccctt ctatgagata ttcgactgct ttaacagatt gacacatgct
    15421 ttcttctatc aaaggctgat tttctttgct gaaaggacta agcacatgct ggactactgt
    15481 ttttttccct tctggcctgc cgattcccac cttgattcga tcaaagacat tcgtattcaa
    15541 atgggaaata atacttttga taccgttatg cccgccggca cttccctttt gacggagccg
    15601 gatttttccc actgccagat ccaaatcatc gtagattacg actaattcct ctggataaat
    15661 cccaaaataa gtcattagtg ggccgactgc acgaccagat tcattcatga atgtttgtgg
    15721 tttgactaaa aggatctttt ctccattatg aaaaaattcg gcaacttctg cttcgaacgg
    15781 attttttttg aaagtagctt gatgctcgcg tgcaatttta tccacgacca taaagccgat
    15841 attgtgtttt gtatattggt atttggtacc tgggtttcct aacccgacga tcattttcat
    15901 ttttgttttc cacctaattc taaaaagcag cacaaaaggc tggactgcta attagcggtc
    15961 cagtccatcg agcttttttc ttttttacac ttgtcaatgc atagtataac acaaaacaag
    16021 gcgtttcggc taaaagagaa tcgttaataa atgataaaga aattaaaaat ttcttcaaag
    16081 tttaatgaaa taattgatat ataaaaatag tgaaataacg cacatgtaag cttttacata
    16141 taatacaacc ttgttatctg ttatatttta tagccaaata gcgtgacatg gggcttgaga
    16201 aatgttagca taagcatggg aaaaaacaaa tcaatggaag gattgatact aaatgactgc
    16261 agctgcagaa aaaaaagatc atcaaaaagt tattcttgtt ggagacggcg ccgtaggttc
    16321 tagctatgcc tttgctctag ttactcaaaa tatcgctcaa gaagtaggta ttgtggatat
    16381 caatactgct aaaactgaag gagacgcaat tgacttgtct cacgctttgg catttacttc
    16441 acctaaaaaa atctattctg ctacttacgc agacgcacat gatgctgact tagttgttat
    16501 tacagctggc gcaccacaaa aaccaggtga aactcgttta gacttagtaa acaaaaacct
    16561 aaaaatcaac cgcgatgttg tcacacaaat cgttgaatca ggatttaacg gtatcttttt
    16621 agttgccgct aacccagtag atattttgac ttactcaact tggaaattct caggtttccc
    16681 taaagaacgc gtaatcggtt caggtacctc tcttgactca gctcgtttcc gtcaagcact
    16741 tgcggaatta gttgacgttg atgcacgtaa cgtccatgct tacatcttag gtgaacacgg
    16801 agattcagaa ttcccagttt ggtcacatgc aaatgttgcc ggcttgcaaa tctatgaatg
    16861 ggtaaaaaac aacccagaaa tcgatgaaga agctatggtt aacctattct ttggcgtacg
    16921 tgacgctgct tacacaatta tcgagaaaaa aggcgctact ttctatggta tcgcagtagc
    16981 attagcacgt atcactcgtg ccatcttaga tgatgaaaat gctgttcttc ctttatcagt
    17041 attcatgaat ggcgaatatg gattgaacga catctacatt ggtgcacctg ctgttatcaa
    17101 ccgtcaaggt atccaaaaag taatcgaaat tcctttaagt gacagcgagc aagaccgtat
    17161 ggctgcttct gctaagcaat taaaagaaat tctagatgaa gcttttgcta aactagacgc
    17221 tgaataatct ttgaacatga cggaaaacat ctattcggtg ttttccgttt ttttatttta
    17281 tcacccttat ggtttctaaa ttttttcata aagtagagat aaccttcgtc ttttcctcta
    17341 aattatgcta tcatgagacc gttccaccct aaacttttac ttaaggagtt gtcgatatga
    17401 caagatcttc gcatcgaaaa aaatcgaaac atgttgcttt gctttcagtt cttggtgttc
    17461 tcttagtgct gatcagcttt tatacctatc gcagtacata ctacacaaag cattttttgc
    17521 cgaatacaga aataaatgga ataaatgtca gcaatctaac agtcgaaaaa gcaaatgaaa
    17581 aattaaaaga agcttattct gataaaaaac tggctattaa agaagatgga aaagtctggc
    17641 aggaagtacc aaaatccgag ctcggctaca aagatgattt cacttcggag ctttctccga
    17701 tcctaaatga acaaaacgga tggacttggg gaatgactta tgtctcagcg gcagaaaaac
    17761 aagaaataga tcctgtcagt caaaaccacc aaaaactaga cactaccgtt cagacattga
    17821 caactaagct gactgatttg aacaaagacc ggacacctac tactgatgca acgatcgaaa
    17881 aagcaggtga ctctttcgtt atcaagcctg aagtcaatgg aaatacgatc gacgtcgatg
    17941 ctgcggtcaa acaattaaaa agtgcggtaa actctggtaa agatacaatt gaattgactg
    18001 aattcaaaga aaaaccaaaa gtaacatctg aagacagctc actgaaagaa caactcgcat
    18061 ccatgaatgc tatcgcaaat gtaaaagcta cttacagtat aaacggtgag actttccaga
    18121 tcccatcaag tgatattatg agttggctga cctacaatga tggaaaagtc gatttagata
    18181 cagaacaagt acgtcaatat gtaacagatt taggcacaaa gtataacaca agtacgaatg
    18241 acacaaaatt taaaagtaca aaaagaggag aagttacggt cccagttggc acttacagtt
    18301 ggacgatcca aacagacagt gagacagaag cattgaaaaa agcgattctg gcaggccaag
    18361 attttactcg ttcacccatt gtgcaaggtg gcacaaccgc tgatcatcca ttgatcgaag
    18421 atacgtatat cgaagttgat ctggagaacc agcatatgtg gtattacaaa gacggaaaag
    18481 tggcccttga aacagatatc gtttccggaa agccaactac acctacacct gctggagtct
    18541 tctatgtttg gaataaagaa gaagatgcaa ctttaaaagg aacaaatgac gatggaacac
    18601 cttacgagag tccggtaaac tactggatgc cgattgactg gacaggtgtt ggtatccacg
    18661 attcagactg gcaacctgaa tacggtggag acttatggaa aacccgcggt tcacacggct
    18721 gcatcaacac cccaccaagt gtaatgaagg aattattcgg gatggtcgaa aaaggaacgc
    18781 ctgtattggt cttctaacaa aaataatata taaaaagaaa gcacccgtac gattggtaca
    18841 ggtgctttct ttttattatc taacaatgtg ctacttacat ttcagcagca gtaaagactt
    18901 ctgaaacatc atcatcgtct tctagcttat ctactagacg ttccaattgc tctttttgtt
    18961 cctcatttaa atcaatcgtc gtttgtggaa tcatcgtcaa ttctgcttgc gccaaagtga
    19021 actctttttc caactcatct cgtacagcag caaaatcttc tggtgcagta taaatctcga
    19081 atacttcagg agaagtttgc agatcttctg cccccgcctc taatacatcc tcaaacatcg
    19141 tctcttcatc aacagtcaac ccatcgcgtt caatagcgat atatcctttg cggtcaaaca
    19201 agtaactgac tgaacccgtt tctcccagtg atccaccgtt tcgagtaaaa gctactcgga
    19261 catttgtcgc tgtccgatta cggttatctg tcaatgcatg gactaagatt cctactccac
    19321 ccggaccata tccttcatac gtgatttcat cgtaattcgt ttcatctacg gcactcgtag
    19381 cctttttaat cgcccgttcc acattgtcgt taggcatatt tgcagctttt gctttgtcca
    19441 caacaagccg caaagctgga ttcatagatg gatcaggacc gcctgcttta gctgccatat
    19501 aaatttcacg agaaagtttc tgaaagactt tccctcgttt tgcatcttgg gcattttttc
    19561 ttccttggat attatgccat ttactatgtc ctgacatgat ttttcctccc ttgttctttt
    19621 gagaatacac ttctattcta gtactatttc acaaaaaaac aaagccacag ccaatctata
    19681 aacgcttctt gaatgccgca aaaagcacac ataatatcac agcagtcaga gcaccgatcg
    19741 aatccaacat gacatcttgg aacataggtg ttcgtccacc ggtcatcatc tgatggaatt
    19801 cgtccaaacc tgcgtaccct gttgctgaaa gccaagcaag gatcgctgtc agccaccaaa
    19861 tttttagctt ggggaaaaca cctaaaaaca agctgcctcc caaaataaaa taggtaccga
    19921 aatgtgcgcc cttccttaaa aagaactcta aaaatttggc gtagcccaga tggttgatac
    19981 tcaccatact tccaccataa ttaaaacgta tacccgctaa tgtgtcttta aatggctgat
    20041 taggcagcca gctttctaat cgcgaaactt gtgattgctg tccgtaagtt tgagaagaac
    20101 tgtaaaataa gattataacg actatcagtg cgattactaa ataaatattt ccgtttttca
    20161 tttgtttttt tgaagaattc ataagtcacc tctgtatttt atcttagact ttttttgaag
    20221 aaacaacaat cattttcata gagacttctt ccataaaaaa gtgctatact taattttgta
    20281 ttacaatatg aagggagttt tttcatgagt tattcattaa attggaatct agattctatt
    20341 ttttccggag gcagtcattc tgatgctttg aaccaacgga tgaagcaatt ggaagaccaa
    20401 atgaacgagt attatcaccg cgtaacaaaa tggtcaccta gttctgacaa tgcagagcag
    20461 ttaaacgcta ttcttcaatt gcaagaaacg attacgaatg gttttaccca atgcagcagc
    20521 tatattactg cattgctttc tgccaatgtc aatgattcag atgcaaaggt cttatcaggc
    20581 aagctttacg caatgctgcc tcgtctgcaa tcagccgaaa ctgtattgtc aaagaaattt
    20641 gcagaaatat ctgacaatga ttggaatcag atgctttctc aatcttcgtt tgaaacaatt
    20701 gcttttcgtt taaacgagat tcgtcgtgat ggctcacaat tattatcaga agctgaagaa
    20761 aacattataa atacgctttc tttagatggt ctaaatgctt ggagcagtca ttatgatacg
    20821 attgtagcca gcatttcgat tcccttcgaa caagatggac aagtagtcga attatctgct
    20881 ggacaagcct tcaataagat gatgggcgat ccagatccaa aagtcagaga aacacttttc
    20941 gcagcatggg aagaagcctg gaaagaaaag gcacccctct tcacggatac tttgaatcat
    21001 ttagatggtt ttagactttc tgactatgaa cttcatggtg tcacagattt tctacaaaaa
    21061 ccattagagt acaatcggtt gaagaaagaa acattgtctg tcatgtggga tacaatccag
    21121 aaaaacaaac aaccccttgt taattacttg actagaaaag ctaatctttt cggtaaagaa
    21181 aaaatggaat ggcaagatca agatgcacct attattttag gcgatttgaa agaaaaaacc
    21241 tttagttttg acgaagcagc agcatttatt atcgaaaact ttaacaaatt cagtccaaaa
    21301 atggctaaat ttgcccaatc tgcttttgaa aagagctgga tcgaagcaga agatcgtcct
    21361 gggaaacgtc ctggtggtta ttgtactgag ttaccagaaa caaaagaatc aaggatcttt
    21421 atgacctaca gtaattctgt taatgaggtt gcgacacttg ctcatgaact aggacatgct
    21481 ttccatagca gcacgatgtg ggatttacct tctttaaatc gcgaatatgc catgaatgtc
    21541 gcagaaacag caagtacatt cgcagaactg atcgtagccg atgctacatt aaaagtcgca
    21601 aaaacaaaag aagaaaaaat caatttgcta gatacaaaac tgcaaaatgc tttagctatg
    21661 ttcatgaata tccattcccg attcattttt gaaaatcgat tctatgaagc acggcaagaa
    21721 ggattagtct cagaagataa gatcacagag atgatggttg aggcgcaaaa agaaggctat
    21781 caaggagctt tagctactta ccatccatat ttctgggctg caaaattgca tttctttatt
    21841 gatgacgtac cgttttataa cttcccatac acatttggct acctctttag tttgggcatc
    21901 tatgcttacg ccaaccaaaa gggagcaaat tttgaagaag aatatatcca tttactacgc
    21961 gatactgcct caatgacgac ggaagatctt gcgaagaaac atttgaatgt cgatcttacc
    22021 caaccagatt tttggcaagc aggtatcgac atggtgactg aagatatcca aacgttcatg
    22081 gaattgacag aagaatttat ctgatttcta ttttatcaca ataaaaaaag agttagtcca
    22141 gaatgggcta actctttttg attaatcatt cttacatgct gacagcaaag tcaggggcaa
    22201 accattgaac tgaaccaact tttacgcttt cgcctggttg aggagcatgg atatattgtc
    22261 ctccgcctaa agcaatcgct acgtggtaag ttccgccttg tgacccccag aataacaagt
    22321 ctccagcttt tgcttgagaa actgaaattt ttgttccagc tgattcttga ggaactgtcc
    22381 aaccaccgat gtcacgacca gttacttgca tgtaaacata gcgtgtgaac cctgagcagt
    22441 caaagccact tggatcttta ccgccccaaa catatggagt accaatatat ttgtaagctt
    22501 ctgctacgat tgctgcacca ttcacacttc cagaaggagc tggagcaggt gttacaggtt
    22561 ttggttgttc aggtgttggt gttggcgttg gagccggagt actacttcct gtgccgtttc
    22621 ctgtatcaac actttgatct gttgatggtg ttgtaggcgc aggtgttgtt gattcttctg
    22681 ttgttgaaga ttcaggcact gttgttgatt cttctgttgc tgaagattca ggcactgttg
    22741 ttgattcttc tgttgctgaa gattcaggcg ctgttgttga ttcttctgtt gctgaagatt
    22801 caggcgctgt tgattcttct gttgaagatt caggtgttgt tgattcttct gttgctgaag
    22861 attgtgtagc tgatgatgat tcttcagtca ttgaagattg tgtagctgat gattcttctg
    22921 ttgctgagct ttgtgcagta gatgaagctt gagtagcttg tgcttcagcc tctgcttgtt
    22981 cgcgtgcttc tttttcagct ttttcttgtg cagcttgttg acgagcttgt tctgctagac
    23041 gttgttgttc acgaatacga gcttgctctg cttcagcttc tgctttttga cggttcaagt
    23101 cagctttctt gtcttcagca gttgcttgtt cagcagctaa tgaagttttc agtacgttca
    23161 aatcagcttg tttagataaa agatcgcctt tttgagattc caaagcagct tggttttcag
    23221 ctaattcttt tagtttagca tcgttttcag cttttttgtc ttctacagct tttttatctt
    23281 gtttttgttg ttccatcaag tcgttgtttg cttttaccat cgttgtcatt gcttgaacgc
    23341 gtccaatagc atctgctaat gaatcagcat tcaatacagc atcgatgtag tttgagcttg
    23401 tgttgcttac ttgtgcttcg cgtgcttgtt tttggattgt atcttcacgt ttttcaatac
    23461 gttcttgtaa atctgcaatg tcttttacta attgtgcaga ttcttgacgc aatgtatctt
    23521 gttttgctaa taggtcttgt gcttgtgtgt tgatttcaga aacttggctt tctaaggcat
    23581 cgatttgtga ttgtgcatct gcttgttgat ttttcaagtc tgcaatcttt tgatcttgct
    23641 gttgtatctg agaatcaaaa tcgtccgccg cggcagcgat cggtgatgct acggcagtca
    23701 aggtcattga acataccatt actgctgata ttaaactctt tttcactctt cattcctccg
    23761 actggcttaa tttaataaat atctaaatat atttaagtct ttcttaacga tataaaaatt
    23821 gtaccatagc agtgtgtcaa cgatataata gttatgttac aaaaatgttt caaaacaact
    23881 tttaaaaatg acaaaactgt tcgtttcaga aaatgatcat gaaaaagccg cgttaagtct
    23941 agcatttctt aagataacaa cgattctttt tcgctttcga cctaaaaata aaaaaagaaa
    24001 ttattcatca ctgaataatt tcttaaaggg aaaaatgaat aatacaaata taatcatgtt
    24061 caacagcagt gtaggtccta aaaaccttgt aataaaatac gtgttattta ctactgctaa
    24121 tttaaaaatc aactggacca ccatcgtaaa caattcataa cccgtgacaa agatgatcat
    24181 actgaaaaat tcagtaaaga tgttgacatg gataacgtct ttcattacat acatcaacca
    24241 tacaattaaa gggagagcta ctgcatagat accgataacg ccaatatagt aagcgtcata
    24301 gatagccccg agaacaatcg tggtaatcag taaataacgt ttttcaaacg ccatactgca
    24361 acataataat gccaatatca gaaagtgggc atttgacata taggtgcctt tcgaccactc
    24421 ccctagcatt cttgttaaat gaccatctat caacatcaaa aagaacaaaa cgattggcag
    24481 atagtacttc attgtttctt tcttcaacat ggactaatcc tccgctagcc gttggacaat
    24541 cgtcacaact gacacgtcat acatttctgc ataaggtttc acataaactt cccgatccag
    24601 cccataacta tctggtttcg ttttaataac cgtaccgatc ggcaagttag ctggagaatt
    24661 ccctccaaga ccggatgtct ggacaacatc cccttctttg atatccgtat caccagttaa
    24721 ttgggtcacc actaaggcat ggagcttttc atcatagttt ttaagcaaac caaacgcttc
    24781 gccattagcc gaagataccc gtactggaaa atgattggag ctttcattag aggatgacag
    24841 taattcgatt ttagacgaag ccgtattgac ctcgatcact cggccaatca atcctttttg
    24901 cgacatgact gccatatttg cttcgatacc gtctttagaa cccttgtcta cgatcagcat
    24961 gtcctgccaa ctgtcaggcg aacgagtaat gacatttgcc gttacttttt cgtaactagt
    25021 cagcgtctga ttcaactcaa gttctttttt caacgcttcg atttctctct cgtaattctt
    25081 gttttgctgt gaaacgtcat catagctatc gattttttct tttagccgct cattttcggc
    25141 ataagttgaa aaaagattat ggacagaatc tactccattt cgtacccacc gtactggggc
    25201 agagattgtt ttatcaacca ttgcaacact gtcattaacg atggattgga agaaattggg
    25261 ctttccttca ttcgctcgct gcgcagcggt cacacttagt atcgtcacca cgatgataac
    25321 aataaccaag gtaataataa tatttttatt aggattgaac ttcttcacaa agacacctcg
    25381 aattaattag actcttgtgt tcaattttat cactaaatgc cgtgaaacaa aaggtaagtt
    25441 gctcctctta agcttttttt tagcaaataa tagattctgt catttttagc ctgaaagaca
    25501 aattttttta tttgtttatg gatcaatctt tgctttgaat aactgcaatc ataccatctg
    25561 aaaaagaaaa ttctgcggta tctgaaagaa attcgttact tgcataagat gtcggatatt
    25621 ctacttcttt attttccaat acatacttgc tgccttttaa tgtaagattc gagacgggag
    25681 tcaagcagca ataagctaaa tacttcatat ctggtatctg tcttactata tgctctccag
    25741 gcaaataata agacaaataa ttttgacaat ctctgataat aagctgatgg gcaaagggtt
    25801 tgaagcgagg ttccatacct aaccagagat tggctaaaag atgatccaat cttccgcccg
    25861 tagctccaat caaagtgact tccgcttgcg ggtaacgttc aaatgttttt aagataccta
    25921 actgtgtatc tgtatcgtct ttttctgcag gggaacgggt atactctttg gcttttgcaa
    25981 atacttcctt ctgctcttcg ttcgacaatg aatcaaaatc acccactgcc agatctactg
    26041 ggtagcctgc ttgaagcagg tacagcgcac cacggtctat cccgacatag gcatcgtatt
    26101 tggacagcag agactgcggc cagttttgcg gattacctcc agcagctaat aaaattttca
    26161 tttagtctaa tgcctctttt aatcgttcga tttgtccgac tggattttcg gctccataga
    26221 tatatgatcc tgcaacgaag acatccgccc ctgcatcttt acagattttt gctgtttctg
    26281 gaacgattcc gccatctact tcgattgcat aagtccaatt gttctctcta cgtagatcag
    26341 cgagttccgt aattttttct actgtttctt caataaagct ttgtccgccg aacccaggat
    26401 tgacagtcat gactagtact tgatcagcca aaggcaaaac atgtttgatc atggagactg
    26461 gtgttcctgg attgataact actccagctt taactcctaa gctttttgtc atttgaagtg
    26521 cccgatgaat atgaggagtt gcttcgacgt ggacagtaat gatatctgct ccagcttttg
    26581 caaatgctgg aatgtagttt tctggatcaa cgatcatcag atggacgtct aacggtaatt
    26641 tagtaacagg acggattgcc tgaacaatat ttggccctaa tgtgatattt gggacaaatc
    26701 ggccatccat tacatctacg tggatgtaat ctgcgcctcc tttttccact aactcaatgt
    26761 ctctttgtaa attggcaaaa tctgcactca aaatggatgg tgctatcttc attcttgttt
    26821 cctcctattt tcgtttacct tctttttttg catacattgg ttttcttttt tcgatttctt
    26881 gtaagaattg caaataattg tcgtaacgtg tctgtgcgat accacctgtt tctactctat
    26941 gttttacttc gcagccaggt tctttagcat gcatgcactc tctaaatttg caatggacag
    27001 aagcttctac aaattcagga aattgtctcg gcagttctcc tgcttcaatt gtcaaaaagt
    27061 caatcgagct aaatcctggt gtatctgcta ctaacccgcc atagatagga atcagttcca
    27121 catgacgtgt tgtatgccgt cctcttccaa gtgcatcaga aatctctcct gttgctaaat
    27181 tcagttccgg tgatatttga ttcagtagcg tcgattttcc tgctccagac tgacccataa
    27241 agaccgatag ccgttctggg aagtaacgga tcagttctgt cgtatcaccc gtatgattgg
    27301 gtacaatcac cggatagcct attttagtat aggtttgctt gatctcttcg attttttctg
    27361 ggtcgtctga caagtcggtc tttgtcaaaa aaataatcgg ttcgatcgac tcgtattcca
    27421 aggtaactag aaagcggtca agtagattat aagaaaatgc aggctctacg atacttgtga
    27481 caatgattcc aagatcaaca tttgtgactg gtgggcgaac taattgattt tttctcggca
    27541 agatttccag aagatagccg tctgtttgat tttcactctc aaagatcacc tgatctccga
    27601 caagcggcgt gattttccga ttccggaaat ttcctcttcc tcttgtttga taggtctctc
    27661 cgtttgcgta tacatagtaa aaaccgctga ttgcttttct gatttgtcct ttgataagtg
    27721 ccacctccgt ttttgtttat tttaccatac gaagaggaaa gtaggtgtta ttccatgcaa
    27781 acttctcaaa gtatatggct tgaaaattga tcaaaagaga tagaaacaca aaaaagagaa
    27841 tgcaacaaat caatgtcgca ttcccttctg atatatttta ttcagcactt attttgaact
    27901 ttctgaggtg ctagctgatg aacttgtgga gctggaagat tcttcttttg aagagttgct
    27961 tgtgctactg gagctacttg agctgctaga actgtctgaa gagtcttttt cagaactaga
    28021 agacgctgga tctggtcctt tagagtaaat tacgttcaca accattcctt tggtaattgt
    28081 cgttcctgcc cctggtactg tacgaatcac tttatcttta tccaccgtgt ttgaatattc
    28141 ggaagtctca tgcccgatat attctgcacc gacactagct aaataacttt gtgcttcgct
    28201 ttttgtatag ccggagatat cattcaattt aggctctgtt ccttggctta cgacaaaatt
    28261 gatgtaagtt tcttctgcta caacttcacc cgaggctgga tcctgactga tgatcgaacc
    28321 tgatggtaca gtgtcgctat agtcataagt agcactaata ttattgatat tgaatccttg
    28381 tgtaacaagc caattacgaa cagtttcgta gttttctcct acatgactac tcaaagtcac
    28441 tgtttctggt cctttgctga ctgtgaaagt aatcgtgtct gttttaggat cgacttctgt
    28501 atcttctgat ggagattgcg aaatgatcat tccgctttct acctctgaac tgaattcctc
    28561 ttctttttga atcaagtcag cagaaaaccc taattctttc aaacttgctt cggcatcttc
    28621 ataactttta ccactgtaat catctaattt gatttttttc gtgccgctac taatatacag
    28681 agtgacttcg cgtttttgct tgactgtcgt tcccgctgcc gggtctgtct tcactacatt
    28741 accttcttcg attttgtcat ctgcaatttc ttctgttttt gttgctactt ctaatttcgc
    28801 ttttgcgagt gtttctctag cagaagcttc agaaagatca gaaacatcag gaacaacaac
    28861 ttctcctcgc ccgccagaag caaagaatac agctgttccg attcctaaaa cagcaagaat
    28921 agctaatagg atcagccacc attttttctg tcctttcttt ttaggatcag gcagaacttc
    28981 ttcctcctct ggtaaggttt cgttttctgg cttgtctttt ggcagaggca tagatttgaa
    29041 tgaatcaggc attggtgcat cttccgtaag gggtgtgata acttttgttt cattatccat
    29101 cacatgaggc tgccattttt cttcgtttgc acgagctggt gataatactg tagaaagatc
    29161 atcagacatt tcctcggctg acttataacg gtctgcaggt tctttagccg ttgcccgtaa
    29221 aatcacgttt tccagtgctt gtggcacatt tggatcaagt gcttttatag atggaagatc
    29281 atcttgaaaa tgttttaaag caattgttac agcagattca ccatcaaacg gtacgctacc
    29341 cgtcaacatc tcataaagga tgatccctaa agcataaata tctgactgct tcgttgccat
    29401 acttcctctg gcctgctcag gggacagata atgaacagat cctagcatcg tattcgtctg
    29461 cgtgatcgat gtttcagata aagcgatagc aatcccgaaa tccgtgattt ttacaacacc
    29521 ttcattatcg atcagtacgt tttggggttt caaatctcgg tggatgattt gatggttatg
    29581 agctaaagaa atagcagaaa ggatctgctg cataatattt actgctgttt cataaggaac
    29641 aggataatgt gtttggatat atcgtttcaa gtccattcct ttgacgtatt ccatcaccag
    29701 atactgcatg ttgtcttctt caccaacatc gtaaacacta acaatgtttg gatgaacgag
    29761 ttctgttgct gctaaagctt ctctctgaaa tcgtcgaatc gcagtctggt cattttgaaa
    29821 gtcaaatcgt aagactttaa ctgctacatc acgatccaag attaaatcgt gcgccaaaaa
    29881 tacatttgcc ataccaccgc taccgatatt tccagtgatt tgataacggc catttaattt
    29941 tttgcccaac tcgatcatac actgtcctcc ttatattcga taagaagaac ggtgatatta
    30001 tccgctccgc ctgcttcatt ggcacgatca atcagctcag ttactttatg agacaatggg
    30061 ccttcttgat tgatgatcgt tcctatttct tcttcagaca gcatgttcgt caagccatct
    30121 gaacataaca gcagtcgatc ttttagttgc caaagatgag tagaaacatc tacttcgact
    30181 gttccaggca tgccgacaga acgtgttaaa atatttttcc ttggatggtt cactgccatt
    30241 tcttcgctga tttctcctga tttgactagt tcattgacta aagaatgatc ctccgtcaat
    30301 tgcatgattt tatcttcacg aatcaaataa gctctgctat ccccaacatt ggcaatcgtg
    30361 aaccagtcat ctgacagagc ggccgctacg attgttgttc ccataccgtt atattccggc
    30421 tgttcttgtc cacgctgata aatcagcata ttttcttctt gaatcgattg aatgaaccat
    30481 tgggcgattt tttcatcgtc aacagcttct tgtttttccc aagcttcgcc tagattcgtt
    30541 accgccatct gactggcaat gtctccggca cgatgaccac ccatcccgtc tgctaataca
    30601 gcaagcttga gacctgaacg gctggtaaat acactggcat agtcttgatt tgtgttacgt
    30661 cgtcttccta catctgattg atattcaatc tgcatttttt cacctcatta ctttttgcgc
    30721 aaacaacaaa tgaaaaatcc atctgtgtaa aactgatgcg gatacaaagt caacattttc
    30781 tcttcgattg atgattgtag cataggattg gtcaaaacat caatcctctc aaaatcaggg
    30841 tgtctttcca agaaagcaga aacaacgtct tggttttctt cttttaagat cgtacaagtg
    30901 ctataagtca gaataccgga agactttaaa gttggtgcgc agctttctaa aatttccaat
    30961 tggatttttg gtaaattcgc taattcatcc ggctgttttt tataacgaat atctggtttt
    31021 cgccgaagca gcccaagacc tgaacaaggc gcgtctacta aaatccgatc aaactgctct
    31081 gcttcgaact gtttactgac ttctctagca tccatctttt gagcgtagac agcagaagag
    31141 acacctagac gtgctgcatt atcttcaatg agtttgactt tgtgttcgtg tacatctaaa
    31201 gcgaccactt ctccaccgca tgacggatct aaaaaagaag caatatgcgt cgtcttacct
    31261 ccgggtgctg cacaggcatc taagacatga tgttcaggct cgatttgcat agacggcgct
    31321 acaagcatcg aactttcatc ttggatcgtc atgacgccat cgtggaacaa tgagctagaa
    31381 gctaaatgcc cttttttcgc tactataccg tatggactga cttggctttt ttcagctgtg
    31441 atctcttctt cttgcaaaac agtgatggcc tgatctctgg aaagtcggcg tgtatctact
    31501 cgggcactag catggctagg ctgatatagc gataaaccga gcttttcagt ttcttcgtat
    31561 ccgatttgat ccaccagtcg tttcgtcatc catagaggca ggctgatttt gacagaaagt
    31621 ctttcgatag gatcagcaat gccttgcaga tctggtgctc cttgacgctg ataattcctc
    31681 aagacaccat ttacaaattt ccctgtccca ggatttcctt ttacttttgc gatttcgacc
    31741 gcctcgttta aaatagcatg tgcagggact ttatctaaaa attctaattg gtatacagaa
    31801 agataaagaa gcatcttgac ccagtcatcc actttttttg ctttagcgat caatggtgca
    31861 acgtaaaatt ccaatagtcg ctgatggcta atcgtaccat agatcaattc tgtaaataaa
    31921 cccacatctt tttgatttag ctcgctttgt ttgatcatct cattcaacaa aagattcgag
    31981 taggcgccac ccttgttcac tcgctctaat gtcagtaatg ccatatatcg tactgatttt
    32041 ttcatttttt tagggatttt tttcattatt tcacctgctg accaatctga acttgctgac
    32101 cgcttccgtt aaggaaatca tgtacggcct gttttccttt accagctggc tgtaattcat
    32161 tgatggctaa gacggtctgt ttaccgcaag caatccatag attttttttg tctttccgga
    32221 tgatcgtacc aggtgctttg tctgtagttt ctgccaatac ttcaaccgat aataatttcc
    32281 agcgtatgcc ctcataggtc gtgaatgcaa ttggccaagg acgcattccg cgtacttggt
    32341 tgtcaatttc ttctgcagtt ttatgccaat cgattgcttc ttgttcccgt gtgatgtttg
    32401 gcgaaaaagt tgcttctgac tcgtcttgag gtactggttt ttgtccatcc aaaatattgg
    32461 gcaatgtttc tagcaatagc tttcttccta aaaggctaag cttttcaaac atcgtcccta
    32521 catcatcttg tttagtgatt ggtatgcttt cttgcgcata gattccgcct gcatccattt
    32581 ttttgatcat ttccatgatc gttacaccag tttctttctc cccattcatg atggcataat
    32641 gaacaggcgc acctccccga tatttaggaa gtaaagaagc atggacattg attgccccta
    32701 attttggtac ttgcaataac ttttcaggca agaattggcc aaatgccgca gtgacgatca
    32761 catcaggcac caattcaatg atttcttcca tttctggcga accggagatt ttctctggct
    32821 gcagcacacg gataccgtgc ttcagagccg ctttttttac cggtgtcggc gtaattactc
    32881 gtttccgccc aactggacgg tcgggctgtg ttaccactgc ctggatctcg taacctgatt
    32941 ctatcagccc ttcaagaatc ggcacagaaa aagcaggtgt gcccataaat actagcttag
    33001 tcatcaagat gttcctccat atattcttca agttcttctt ccgggatctg ctgtatcatt
    33061 ttctcaatga acaagatacc gtctaagtga tcgatttcat gctggaaggc acgggctaaa
    33121 tagccaaaag ccgtcacttc tatctcttct ccgtctcgat cataataacg cacggtcact
    33181 tcatctgctc gcttgaccgt tccatagaca tgcggaatac tgagacaacc ttctacgtca
    33241 aggctttcac cttttgcttc gatgatttct gggttaatca gttcaaattt ctcgccttca
    33301 tctacttcga tcacagcaat tctcttgttt tgtcctactt gaggagcagc gatccctatt
    33361 ccgtcattcg caatcattgt ctcatataaa ttgtctaata aagcgattgt ctcgtccgtg
    33421 attacatcga ttggctgagc agttcttttt aatttatcat tagggtggat caatatagga
    33481 tagcgcataa tttggccctt tcttaaataa agtttaatgg ttcgttgtca attgccacaa
    33541 aaagaccttg tcgctgttct ttctggcttc cattcaaaat ttcatccaaa acatgaggaa
    33601 gattcggttc atgtttatat ttgatgatta gttgataata atatcggttt ttcactctca
    33661 aaatcatgct gggcgttggc cctaatagca agctttgagg gcttaacact tcttttagct
    33721 gattggcaat ctgaaagatt ttctttgccg ctacttgttc ttcaggatgg ctggcggtta
    33781 ttttcacagt aaagtaataa ggaggatagc ctccacgatg ccgtacatgc atttcctgct
    33841 gataaaactg ctcataattt tgttttttag ccaattctat ggcgtaatgt tgaggattga
    33901 atgtttggat cacgacttcg cctgcttttt ccgctcgccc tgctcgtcct gaaacttggg
    33961 taagcaattg gaatgtatgc tcactagaac gaaaatccgg taaattcagg gaggtatcag
    34021 cattcaacac cccaactaat gtcacttctg gaaagtccaa acctttagca atcatttgtg
    34081 tccctaataa tatatctgct tcttttgcac cgaatttttg taaaatctgt tcgtgtgccc
    34141 cttttcttcg agtggtatct acatccatac gcaaaatcct agcttgcgga taaagttctc
    34201 ggagttcctc ttctactttt tgagtacctg ttccatagta gcggatttta ttgccgccac
    34261 aattaggaca gcgattggga ataggttctt catgtccgca ataatggcag cgcattgaac
    34321 gtgtatccat atgcagtgta agagagatat cgcaattagg acatggaaga acaaatccac
    34381 agtccctaca catcacaaaa gacgaatatc ctcgacgatt gagcagtagg acagtttgtt
    34441 cttttttgtc taatcgattt tgtatttttt cctgcaaatt agcagaaaaa gtagaggtcc
    34501 gatgattctg aaactcttca cgcatatcta cgatctcaat agctggaagc tgtgcagctg
    34561 ctttggctcg gtggtttaac tgcaataact gataaacgcc tttttgagct cgtgctcttg
    34621 attctaaaga gggcgtcgcg cttcctagaa ctattgggca atgatgatat ttactgcgcc
    34681 aaattgctag atctctcgca tgataacgcg gtgtctcatc ttgtttgtaa cttgattcat
    34741 gttcttcatc gataatgatc agcccgatat ttttcagcgg ggcaaaaata gcagatcgtg
    34801 cgcctactac tacttgcgct tcttcccgct caatcttgcg ccattcatca tatttttcac
    34861 cttgggaaag tccgctatgt aagaccgcaa ctgattctcc gaagcgtcct ttgaatcgct
    34921 cgaccatttg cggagtcaat gcgatttcag gcactaacat aatagccgtt ttattttctg
    34981 acaaaacatc agcgattgcc tgaagatata cttctgtttt cccgctgcca gtgattccct
    35041 ccagcaaaaa gacctgatct ttttgctgct gacctgctgt gatgatttgt tcgacagcat
    35101 ttttttgttc tgcattcagt tccaatgccg tcgtttggtc aaatactcgg tctttataag
    35161 ggtcgcgata acgttctgat tctataaact ccagccagcc cttttctttt ccttgattca
    35221 agacagcagt actgattcct ttatttttga aataagcaat tggttcttct tggctcagtt
    35281 cagataaaca caaaagaagt tctttttgtt tcttggcatt ttgccgtaat tttgcccatt
    35341 cttcttcgat ttgcttttca gttaacaaag aacggaccaa acgaatcgtt tttactttat
    35401 ttcgtgtatg gacttcatat ttgatatcta ctaattgctc ttggcgccag cgaatcaatt
    35461 gagaaaggct gccttcttct tctgcttcct tccaggaaat cacttctcgc tgatcaaaca
    35521 atacctgaac ttctggtgtg tctgccaaag gatagatcaa tttatcatat tctgctttca
    35581 tcacactcgg aagcatcgtt tgtagacaag tgattttgaa tgcgtaagta atttttttca
    35641 tataatcagc taatgaaagt aattcttcat tgaccaccgg agcaaggtct agcaaacgaa
    35701 taactgcctt caaagatgga ttagctgatt cttctgattt ttggatagcc ataacaaatc
    35761 cttggacatg acgattgcca ttaccaaaag ggacttctac tcgcatcccg acttgcaaag
    35821 ctgtttccat ttcagaggga accaaataag tgaatggctg atcggtctgc atagtaggta
    35881 cgtccacaat gacttcagct gttaatgtca tggttcgttt cctccttttt ttgtcttttc
    35941 ttatcaagcg acaaaaagtt ccttgcctat tttactagag atcgatggat ttgtcttatc
    36001 ttctgccaaa tcctaacaaa aaattaacag cagataagaa aaaaaagaac tgtgtcaaaa
    36061 agttcagaca cagccttttc taccagacaa taagtggcga atgtttgaaa aggaaacagc
    36121 tgggtttgct tttcttttta gatgttcgct ctatttttct ttattacatt ttttgctctt
    36181 cacggatacg tgattccaat tcgtgttgtt cacgctcttt ttgtgcttga cgttcctctt
    36241 cttccatctt caaacgttca cgttttaatt caggatgtgg atcattgact acatttcctg
    36301 catcgatttc ttctaaagct tgaccgacgc tttttactga atcaaaagaa tctagagtag
    36361 gctgtgcact tgcatccaat tcatgcgcgc gtttacttgc taaaatcact agagaatatt
    36421 ttgaatttac acgatctaat agtgagtcaa ttgaaggttt taacatcata agactacatc
    36481 tcctttaaca ttttaatata tttaccgatt acgcgatcta ctcgaaaatg ttcactggca
    36541 ataatgtttt tgattcgttc aactgctagc ggcacttcat catttacaac agcatagtcg
    36601 taaagagcca tcatttcgat ttcttctttt gcaactttca ttcgtttttc gattacttca
    36661 tctgcatctg ttcctcggcc tacgatccgt gattttaatt ccgctaaatc tggcggagtc
    36721 aaaaagatga atacaccatc gggcactttt tctttgactt gttttgctcc ttggacttca
    36781 atctccaaga aaacatcttt tccttcatcc aatgtcttgt tgacatatga caaaggagtt
    36841 ccataataat tcccgacata ttctgcgtat tccagcatct ctccagcttc gatcattgat
    36901 tcaaactctt ctttgcttcg gaagaaataa tcaacgcctt cgacctcccc ttcacgcatt
    36961 ttacgggtag tcattgagat cgaatactga aaatcattat cctcactctc aaaaattgct
    37021 tttcgtactg tgccttttcc tacaccggat ggaccagaca acacgattaa taatccacgc
    37081 tctgacatga cgacgtcctt tcaactagtc tttttgtact tatcgtttat tttgcacttt
    37141 ttttctgcaa ctttcaaggt tatctttaat tatagctaga aattggtaaa aaagctaccc
    37201 tgtaccaaga ggtcgtaaaa aagctgtcct gcatcaagta ataagaacag ccaaacataa
    37261 acagcttctc atgtttttcg tttggttggg gttattatcg cagatgcaag cttttgaacg
    37321 ccgtgtataa gaggtcgtga agaagccgat tagtttcgag tatgaagaaa aattttgtga
    37381 aaatagtttc tcacattttt gcataaattt ggcttaatac cgagaaaatg gtttttgaac
    37441 atcacttatt caaaataaaa aaagattgtg acacgaattt tgtcacaacc tttaaatgta
    37501 ttcctagagc aaagaagcta agcgaagaaa tccaattctg tttatttatt gtatttcttt
    37561 gttcagcatc cttgctaaaa gcccatattg gacaaagtat tcactacacc catgatctca
    37621 tcttttcgag aacgtgcttt ttctgtcgga tcttctacct cttctgtgtc aattcgaaca
    37681 ataaatttcc gattcatcgt cacgtaagca ccgtcgttga tcaaaataaa cagttcgttc
    37741 tcattatagt ctgcacaggc atctttccat acgtcaaagc cgtttttttc agaagggata
    37801 tcccgtttaa ccacagtttt tccacttaat tcgtggaacg ttacgtcata atatttcatt
    37861 atctctacct ctttcgtcat tcaatatttt gtacttgttc tctgattttt tctaagatcg
    37921 tcttagactg gacgacttga tttttaattt cgattgcatt tgatttggaa ccgatcgtgt
    37981 tgatttcccg attcatttct tggatcagga aatctaattc ccgacctaca ggacattgtg
    38041 cttcgataag ttcatctagt ttttgtacat ggatcgccag acgatccagt tcctcgtgaa
    38101 tatctccgcg ttccaacaag atggctagct ccgtcaacaa ccgttgctca tcgactttcg
    38161 ctccaagaaa ttcctccagc tttttttgat accttatttg aaattccttt tcatagattt
    38221 ctacaaaact atcgagtttt tttagtactt ctttgaattc ttcagtattc tttttcaaca
    38281 ctaaagctaa agcttgacct tctttttctc gactcgcctc aatagaatca agtgcgcttt
    38341 tcaatgtatc tagagctaac tgtgccaatt cttccatgct ctcttccggt ttttcttcta
    38401 ccgttacgaa gttttcgtcc agcacgaagc gttccgccat ccgactaatt gacacttgat
    38461 tttgactacc gtatcgttgt tgaattccgt ctgtcaattg agtgataagt gaatcaatca
    38521 attcccagtt gatgacgatc tgtttttcgt ttttgccaat ataagctaga ttcacaaata
    38581 cttcgattcg accgcggctt aactgctgtt taataagctg acgaaaatcg ttttcaacaa
    38641 agttcaggat tttaggactt cgtatttgaa catctagaaa acgctggttg acacttttta
    38701 tttcaatatc taactgatac gcttttgttt cgcggatggc tttgccaaaa ccagtcatac
    38761 ttttcattcg acagggtcct tcctcattac atattttcta ttgctttttg cagttgttca
    38821 aactcttcgt tcgtcaatgt caggcctttc cccatttttt catggtctgg cgcccaatct
    38881 cgaagatcga attttggcgg gcgaccattc cagctgacta ggttcagttc tttacgccac
    38941 cccttgttgt tttctgacaa tatagcgatt tcttctacga tttcatatga aaattcttgt
    39001 gccatggttg ttcctccttg agataatata aatataggat cagtaatgtg tcaactggtt
    39061 gcttaagcaa ttcatgctgc aaacgatcct tgcgttttcc ttgtagcaga taatcaaaat
    39121 aaacagtttt cgtgcgctca ttttgtattt tttgctggta ttttcgatac cttcgccatt
    39181 cttcagtact taattgacca atttgtgcca ataaatcatc cggcatactt tttatatctt
    39241 gttggcagat catttgaatc atcatgtcta cttgatagat ttcattgggc agtaaaaaat
    39301 gtttttttgc taaaagttct agcatcgcca atccgcatgt ctctggtacg accctgttct
    39361 tatataaatt acgcagtttt tgccaaaatt ttatgctttt gaaaaaagat aattctaact
    39421 gaatttcttt tgttaagtaa gacaaaaatc ctcgccagta tgttcttgca ggtttaacag
    39481 aatgaaatgt ataccagttc ccatagtaat agcctaatcg ttttttcatt tccagatagc
    39541 ctaattgtaa atttaattgg ttcctttggc tatcaaaaag cagaaagctg cctagtgtcc
    39601 acaatgtttg acatttccaa tggataaaaa tgtctggcat acgaattttt ttcgctgggc
    39661 ctggcccttg cacatctacg acaaatgcct ctgttgctcc tttgttaatc gcaatatcaa
    39721 taggtatttt gttgcgatac ccaccgtctg catatttatt ttttccgatc tttcgataag
    39781 ccatagcggg ataaaatgaa gcagaggcga gtatccaatc tggtatttct tctgtttttg
    39841 tctgttggat atcagtcact acttccgcta gttctggcag tttagtagac accgtatata
    39901 aacgtatttt gggattatgt ttgagtaagg acaaatccaa attgtctttg accatctttt
    39961 ccaatggagc agaagaaacc ccgccttcaa ttagtgctgt tttcgtcatt tggcgtcttt
    40021 ctcgatagaa gcgttcacga aggtcttcaa ctgcagccat ttctggtaac gcaagcactt
    40081 gtcttgtcga cagctttttc cataaattca cagctttttt catatctcct tgtaaaatca
    40141 atgcgccgtt caacgcacct accgaggtac ctgtgataat ctcaaagttg atatcatgtt
    40201 ccttcagcgc ctgccacaca ccaatctgat aagcaccgtg cgctcctcct ccacctaaaa
    40261 caagtgctgt atgatagacc agctttttat ttaattgtgt ggttccttga tagccgtttt
    40321 tatgaaaaat acgcaaccat tcttctgata gaggagattg aaataaaaaa caacagtttt
    40381 ctttaataaa aaaacgagcg caagcttcca tataccgaaa aaattttttc cattcaaaag
    40441 tttcaccttc aatcaacaga ttattaaaaa taacatctcc tctactttta gcaatagtaa
    40501 aatagacggt atattttttc gatactgctt taaaagcaca ttgctttttt gcagaacgcc
    40561 aaaaagcgtc tctactttct tgatgacttt gaaaaaatgg aaggggttgt tttgcttgct
    40621 ggataggcga atacagcgac attttctgtg aaaagtaaac tttttttatc tccatcgcgc
    40681 tctccttttt cttcaagtat accagtacgt cataaaaagg tcatgagtct cgtattcgac
    40741 tttgtagatt ccataagaaa acaattcata aaacctcctt taaataaaaa aatacaaaaa
    40801 tcacaaaaat taattgaaaa tgagagtgtt ttcaatgaaa acgtgatttt gtaatggaat
    40861 tttaaaataa aagaaacaag cttttttaat gcaaatgttg taaaataaaa gagattaaga
    40921 ggaaataaga ggaggaacat gatgactgag tcagtttatg tacatattga taccacaagt
    40981 aatgctgttt taacaaaagg gctgactgct actgactttg caaacagtat cgtgcatttt
    41041 cctcaaaact tgctcttgct tgatccatct gcttctgctg gagaatatga atcccataca
    41101 gggctgaaag taatccgtgg tacagaaaat attcagcgtt tcttttcctc ttctcgtaac
    41161 aggcgtggat tcgatgaatt gaagtggatc gactttactg atttaacgat gctgaaagaa
    41221 ttgacacctt tagaaatttc agaattatta tattttggtc atatgaaaac acatcttcat
    41281 tcgccgtttt tttataaact acagaataat tttgtatact tcgatcttaa tgatcagctg
    41341 aatcggattt attatcgcta tttagatgaa ttttatagga tttttgctag taaattaagt
    41401 tcgatcttgt cagataagat caatgtaaaa aaatcttttt tcaaaaaaga aacacctgtt
    41461 gaaaaaatca gtgtggaatt attgaaagaa atgcgtaatt tgatgcagga agggatcatt
    41521 ttttcttttg atcaagttgg tttgatcgat ggtaaatatc gtatcccaat ctatgtgatt
    41581 gaagattata tttggaaatt aaaaggcacc cggtatcgag aagaggaaat catcgctact
    41641 ttaatctact ctgtcaccga tcgacactgg caattggtag aagatgccga tctttcttat
    41701 ctgccattga agtagatcta tttcttatca aaaaataaaa aggaaacaag aaactaggac
    41761 atgattctgt ctcaagtttc ttgcttcttt tttatttaca gctcctgtcg tttatctggc
    41821 acaaaaatcg aaggagtcgt ttgttggatc cctaataaaa cgatgatcgt tacaatagct
    41881 gtactcaacc cgctggcacc attcattacg aaagaaaaga gccaaggatt catcccccat
    41941 agtgcatacg ctccccagaa aaccactcct gcaataaaat gccaaaaata tctggaaagt
    42001 gcgccaatca atgcaccaaa cacgatgctt tttctaattt gtttcgtatt atcgtctaca
    42061 tagccttttt ggacatttga agccatgagc cctgctgcgc ctgcaaaagt ataggcaatc
    42121 gggtactcaa tcaacacttg aacgacactt aaataataaa cttgtcccaa cggaaaatgt
    42181 aggatgcccc aaatgaaacc tgccagcatc cctgcctttg tccctcttct taacgcaaaa
    42241 agagtcaatg gaatctgccc taatgaaata gaaaaactgc tgccgatctg gatcggaatc
    42301 aacgacaaca ccatcgctaa cgctgcaaca atcgttcctt ctacccaaac tctatttttt
    42361 cccataaaaa aacttcctcc tttgaataaa aaagtcacaa aggaggaagc agctttcgaa
    42421 aatagtcaaa cagctgttta ttcacaattc ctacgctcgc ataaccgata caggtacgaa
    42481 gggtttagaa atagattcaa tctcagccca attggactcc cctttgtgag tttatttatt
    42541 atttattttt tgtttcaaac aatggactaa ctggtttgtt ttcatggata cgtttgattg
    42601 catctcccat tagtccgcca acacttactt catcgatttt gtcgatttta cgatcttctg
    42661 gaagatagat cgagtctgta acaactagac gctcgatagc tgaatcttct attctttgta
    42721 aagcagggcc ggataatact ggatgtgtac atgaagcata cacactagtt gcaccagctt
    42781 ctttcaaagc attggcagcc aatgtgatcg tacctgctgt atcgatcata tcatcgatca
    42841 gtacacaagt tttgcctttg acttgtccaa tgatattcat tacttctgca acatttgctt
    42901 ttggacggcg tttgtctatg atcgcaatcg gagatttcaa aaattccgct aatttacgtg
    42961 cccgtgtgac accaccatgg tctggtgaaa caacgacaac atcatcgcct ttgattcctt
    43021 tttctaagaa ataattggca ataagtggcg cacccatcaa atgatcgact ggaatatcaa
    43081 agaaaccttg gatttggact gcatgaaggt ccaaagtcag cattcttgtt gcaccagctt
    43141 tttgaatcat gtttgctact aatttcgctg tgattggttc ccgtgcacgt gctttacggt
    43201 cttgacgcgc atagccataa taaggcatga ctacgttgat tgtttttgca cttgctcgtt
    43261 tcagtgcgtc aatcatgatc agcaactcca tcaagttatc attgactggg ctgctcgttg
    43321 attgaataac atagacatgc gatccacgaa tactttcttc aatgtttact tgaatttctc
    43381 catcactaaa ttgagtaaca gatgattttc ctaactcgac gccgactgct gctgcaattt
    43441 tctctgctaa tgggcgattg gaatttaacg caaaaatttt taatcttggg tcaaagtaat
    43501 gttttgacat ggggacctcc actttctttt tcacaactct agaattctac ctaataaata
    43561 gtagtcatat tttttaaata aatcaagtga ttttgcaaaa gtcttagttt agataaggga
    43621 gtttttttgc atatccttct ttattgactt gtcttgctct cgcaattgcc agcgcatatt
    43681 ctggaatatt gtctgtaatt gttgacccgg cagcaatcga actgttttta gctacctcga
    43741 caggtccgat gatattcgtg ctagaaccaa taaagctgtg gtcgccgaca gtcgtatgat
    43801 gtttgttctt tccatcatag ttgacgaaga caacaccaca tccgacattg atttcttctc
    43861 ccagcgtagc atcaccaaca taagtcaagt gaccgacttt agttcctttg ccgatttgag
    43921 catttttcac ttccacaaag tttccgatat ggacgttttc gccaatttca gcttttggtc
    43981 gtaaatgtgc ataaggtccc acatctgcat gtttcttgac atggctgctt tcaatgactg
    44041 agttttcaat gacgacgtga tcctcaatcc tactgtctac gatttttgaa tgtgacccga
    44101 tgacacaatc agaaccaatg actgtatttc cttggatttg tacacctgct tcgatcaatg
    44161 tgtctggacc gatttctacg cctgcatcga tgtatgtcgt tgctgaatcg acaaagctta
    44221 cgccattgac catatgcatc tggttaattc gctttctcat gatctcattt gctttagcta
    44281 acgcgatccg atcattgact cccattgatt cttcaaaatc atccgtttga taagcagcaa
    44341 ctgtatggcc ttcttctttt aagatttcga tgatatctgt tagatagtat tcaccttgag
    44401 cattgtttgt tccaactttg cttaacgcat cgaacaaagc ttcgttgtca aaacagtaag
    44461 ttcctgtatt gatttcttgt acaagagctt cttctggtgt tgcatctttt tgttccacga
    44521 ttttttctac gatcccaata tggtcacgga tgattcgtcc atatcctgtt gggttttctg
    44581 cttgtgccgt caagatcgtt gcacttgcat tttttccttg gtgatattca aaaagattgt
    44641 tcagcgtttc agtagtcaat aatggtgtat cgccactgat aactaacgtt gttccttttt
    44701 ttccttccaa gaaagaagca gcttgcaaaa cagcatgtcc tgttcccaat tgttctgctt
    44761 gtaacgcata tttactgcgt tctcctagtt gtgctttaac ttgttctgct ccgtgtccaa
    44821 cgatcgtaat cacttcatct ggtttcgttt cactgacccg attaatgata tgttctacca
    44881 taggtttacc agaaacggga tgtaaaactt tatataattt tgacttcatg cgggtacctt
    44941 tccctgccgc caaaataatt gcataacgtg cgtccaactg cgtcactcct aaatatagtt
    45001 tgctgatttc agtttatccc agtataccca ttttttcaac aaaacaagtg attttctttt
    45061 atcccagcgt tttctggata aaaaaataga tagaccataa cgggcctatc tatttggtaa
    45121 ccggtgctct cctgccaact cctcggtcac aagtcacact actcataaaa catgaaaagc
    45181 tgttttttga aatcgtttct tgtgacttag agttaaacgg taggcttaca acctcttcat
    45241 taaacgtttt tcaatcagct gaccttcggt attagctcaa taaacggcaa aatatgagga
    45301 gcaatttttc cgtttattga gctaatactc aggacaggac gctgatttca caacctctag
    45361 ataaacggtg ttcaaaagcc agtttctcgg tattaagcca aatttatgaa aaaatgtgga
    45421 aagccatttt cacaaaattt ttcttactac tcgaaactaa gcggcttttt cacaacctct
    45481 tattctgaaa aataatttcc tggcacaacc gtaatatttt tcgtttgagt atctacatct
    45541 ttgacataaa gcagtgacgt ataatcatcg atggcgcgat gaccgttgaa ttttgattcg
    45601 gcaaatacag tgatgccaac aagttctgat tcgaattctt caatcaagct cttcattccg
    45661 ttgactgttc cgccgccttt catgaaatca tccactacaa ggacacgtga accacgtttc
    45721 aaacttctct tagacagttc catcttttca attctttcag aagatccaga cacatagttg
    45781 acacttactg ttgatccttc tgttattttt gagtcccggc gtacaataac gaatggcgca
    45841 ttcagataat aggacacagc ttgggcaata ggtacgcctt ttgtggctac agtcattaca
    45901 gcatcgattt tttcaccaag gtatttagaa gcaatgattc ttccaacttg acgcagcagt
    45961 tcaggttctc ctaacaaatc agagagataa acatatcctc ctggaagcag acggtcttgt
    46021 tctgatagac gttctgctag agattcaata tattttttcg cctcttcata tgaaatttca
    46081 gggatgaaca atacaccacc tgcagcaccc gggattgttt ccaaggttcc ataccctcgt
    46141 tctttaaatg ttttcttgat gattcccaaa tcttcactga tagaagattt agcagattca
    46201 taacgttcgg caaagcttgt taaggaaatc aattcatgcg ggtgattcaa taaatactgt
    46261 gtcatgtcaa ctagacgttc actgcgacgt actttcacct attccaactc cttttaagaa
    46321 attttatcgt tttacattat ataagttttt cttcaaaaat tcgagcattt tatgaaaaaa
    46381 taagaaaata gttcggtatt tattaaaata aaaagaagcc tataaaaaat ttttcgtttt
    46441 tataaggctt cttttcttta taatttagtt attttttctt ctgaaggcaa ccaatattcg
    46501 tttgatgata tttacaatca ggaacaaagc aataaagact aatgtgattg ttgctcctgg
    46561 aggtgtatct agataaaacg agctagttag tcctgacagc atccctagaa atcctacaca
    46621 aacactgata gcaatcacga cattgaagct tttgcctaat cgcataccga ttgctgcggg
    46681 aagaaccatg attgcggata tcaaaagtgc accggcaatc gggatcatca cagcaatagc
    46741 cacaccagta atcacattga acatcatcga catcaaatga acgggtagcc catccacgtg
    46801 ggcggtatct tcatcaaaag tcagaacata catcggccgt ttgaataaaa agaacaatat
    46861 accgatggca acgaataaga ttcctaaaaa gatgacttgc tcccatgtaa tggtcacgat
    46921 cgaaccaaac agataggatt ggatacttgt tgctgaattc cctccgctca aattcatcaa
    46981 tactaacgct agcgccaaac caccagccat taaaatggca atggagattt ctgaataggt
    47041 tcggtagatc gttcgcagat actccaatat cacagctgct aatacaacga ctagcatggt
    47101 cgtaagtgta ggattaaggt tcaaaaagaa tcctaacgct acccctgcta aagagacatg
    47161 agaaagcgta tcagccatca gcgattgtct tctgatcact aaaaacacac ctagcatcgg
    47221 ggcgattccg gcaatgaaga tagcggcaag aaacgctctt ctcatgaatt catatgaaag
    47281 caacgccatt gagaatcctc ctttctcacc agtcggatct gtctgtccgc atactgtttg
    47341 atatcttcat gatcatgggt gatcattaga actgatttcc catggacatg cgcactatgt
    47401 cggagaagac gataaaattc atttctggat tcttcatcca tacctgttgt tggttcatca
    47461 agaacaaata agtcagggtc agtagcaaaa atacgcgcta aactgattcg ctgcttttgt
    47521 ccgccagaca attcacctat tcgccgattt cgcatatccc acatccctac agcttctaaa
    47581 gcacgctgta catgttgatg atctttttca gagagacgct tgaaccagcg gcctcttgga
    47641 tatcttcctg aacggactaa ttcgatcacc gtactaggaa aacctgcatt gaaagatgca
    47701 acttgttgag gaatataacc gatacttaat ttttttcctt cttgattttt ctcagcaatc
    47761 tttatcattc cttttgaagg tttcagtaat cctaacgatg ctttcaccaa ggttgacttg
    47821 gctgctccat tttctccagt taaaatgaca aattcacccg catctacatg ataagagaca
    47881 tcttctagta caggttcatc atcatagtaa aaggtcaaat cagatatttc gatataacgc
    47941 accttacaac ctccattcta aaacttaatt gatactttct tttaaagctt tcagattttt
    48001 ttccatgaca gaaatataat tttcgcctgc tttgatttgt tcattagtca agctttctaa
    48061 aggattcaac acttctagct tcactcctgt ttcattcgac aatgtctcag ctaccttcga
    48121 agaggcattt tcttcaaaat aaatcacttt gatgttgttt ttcttcacaa attcttttag
    48181 ctcagctaag cgacttggtg tgggttcctg atctggtgaa acgcccgaaa tcgctacttg
    48241 ttttaagtcg tattgattcg ctaaataagc aaaagcagca tgctgagtga caaatgtgcg
    48301 gtttgttgca tcttttagct catcggagta tttttgatcc agtgcttcaa gctttttgat
    48361 ataagcatcg gcattcttcg taaaagtttc ctttttatct ggatattttt cgcctaattc
    48421 ttcagcaatc gttctgactt cttttatagc taataccgga tcgagccaaa catgtggatc
    48481 gtattcatgt gaatgaccat gcccttcttc tgattcttca tgttcgtctg cttcttgcga
    48541 ttctaaacgg tcgattcctt tagctgcttc gatcatcaag gtctgtttgc tatccactga
    48601 atcctttaac gaatccacaa aaaattccat gtctgaacta ttatacacga aaacatctgc
    48661 atcggaaatt tctgctcttt cttttgcact tggttcgaaa tcatgcggct ccgttccagc
    48721 agggatcaaa agtttcacgt ttccttcatc ccctacgatc tcttttgtaa aatcatacat
    48781 cggataaaaa gtcgtaacga tcgtcaaatc ctcttttttg tctgcttcct tgttcgtatt
    48841 tccacatgct gcaaacagta aagcacctat cattaccgta gctgtcaaaa gatatttttt
    48901 catttatatg ctcctttcaa tgaacaaatc ggaattttac gatttattaa cgtgaactaa
    48961 tgtatcaaaa taaaaaaaca cagtcaatag aaatccatca atttctgatt taagcatgta
    49021 tattcttgat taaatcgtaa aatggatgag ttgctgctca tatctagcca tttcactaca
    49081 ataaaaaact gaagaatacc attttaggat tcctcagttt ttcatcacct attttacttc
    49141 ttatatttta ttgcagggtt cgtactaaat aaacttcctc acaaaaacct tttaacccat
    49201 tatatactct ctgcgctctt gaataatgtt gacacaaggc aaaaacggtt ggtccgcttc
    49261 cactcatcaa tgcagcatct gctccgtact tgatcatacg ctctttgatt tgatggatga
    49321 ctggatgccg ctttcccgtt atatcttcta aactgtttcc catttttttg atcatctgct
    49381 gataatcttg ctctcggatg gcttcagcaa gtccgtggat gtcttgatgt tggatggctt
    49441 gcgtatctac ttctctaaac actgtacgtg tagagacact cattcttggt ttgaccaaca
    49501 caacccagca ctgtggcata gaaggtaata cttggatttc ttcccctttg ccaccgacaa
    49561 atgccgtact tccgtagaca cagtaaggaa catctgtacc gacttccaaa ccgatttctg
    49621 ccagttcttc taacgaacag cccagattcc ataattggtt gatccctctt agagcagctg
    49681 cacagtctgt acttcctccg cctaatccag ctgctactgg aatattcttc ttaacaaaga
    49741 tcttgacacc ggttttgata ttgtatttat tttttagcaa taaagcagct tgataaacat
    49801 tgttccgttc atctaccggt aaaaatgctt tatttgtttc tacaatgatt ttgtcttctg
    49861 ttatttcttc aaaaaataga tgatctgcca agtctacgct cgacatcacc atttccaact
    49921 catgataccc atcttgccgt ctatataata catccagtcc taaatttatc ttggctggcg
    49981 ctttttcaat caattccatc ctctcaccca ttcgaaaagt ctaagtcgca agtattctat
    50041 catagggaaa aataaaagta tagcttatgt ctgcctagtg gttgattttg tcatcgtttc
    50101 aacagctttc acagaatttt ctcttcataa tccaaacaag ttctagtgat tcttataatt
    50161 ctgtgagcac ttcttctgcc aaactcggaa catttccttt ttcttttcct atcagactga
    50221 gtagctgcat ggtagcaaat ccgaaattac ttcctttcct ataagcaaaa taacgtcctt
    50281 cccaatgatc gacatatttt aatttctttt cataagcaga ctggaaggaa tagaaaaaat
    50341 taccataatt atatacgata tgcatgactt tttcttgaaa gaaagaaaaa tctgtttctc
    50401 caacattagc taatggagct aagcctagat tggcttccga gtagcccatt ttctcgtata
    50461 caataaacag attggctaac agatagtcag ctaattcctc agattcttta ggtaagaccc
    50521 gcaacaaatc atatcccgcc tgcttcttcg tcatcggctg agcggtgatg aagccaacga
    50581 ctttttgatc tttacggaca ataccgacac cgctagataa tacatatgat ttatcaaatc
    50641 gtcccacaga gaagtatttt tctcgtgcac cttgaagcca tttttgtgaa acttcattta
    50701 cagcttgatg taattcttcc ggcagttgat cgtaccaagt aaaatggtat ccttctttca
    50761 tcaaacgttg atattcaagt tgctgactca gccgagacaa gtcttctgtt gctagatcaa
    50821 caatccctgc ttcacctact ttcgtgaagt gaaaacccaa ttcatgaagc atcactacgt
    50881 agctttctga tatcttataa aacgcaagct gatagcctaa acaatctgct tgtttcataa
    50941 actgattcgt tgctgcccgc atcattttag gattgccaac tggatctcct aaaacaaagc
    51001 atttgtttcc tttgatctga taaccaaaaa cgacttgatc ttggtcgtct tcttggtaat
    51061 aaaaataact gtaacctgac aagcgaagct gatggcttgt agctgtgcct ccgtatgttt
    51121 ccaataaacg gtcaaaacgg tctttttcgt actcactgcc aagcttcgta gtatcttcag
    51181 ctaaatattg ataaagcgcc actaaagcta gcaatgagat gcccaaacca ataagccctg
    51241 agaaccacac atcatctgaa ggaaacaaaa taaaatgatt tcctgttatt cgaccgacta
    51301 aaaagcgtcc gctgtgatag cctgcaattg cgtaaacgat aaacaaaaag ccgaacaagc
    51361 tagcatcaaa gattatagct ccccaagaat aaacgaattt tgttcgataa aattcttttc
    51421 tggataacca cacagctaac agaatcaaga catataccaa tatcaactgc caagataacg
    51481 tacgtgtgat tgtatttaaa ataccaaaag atagtaaagc aatcgtaggc agaaatgcct
    51541 ttttgacttt tactgaaagt gctctagcaa ggccgagtaa taaaaagcca accaatagat
    51601 tcactgtctg atctaaaaaa ttgaatgaga acggcaataa tacttgaaat agccgactga
    51661 ttgcagacag attagtgatt gttgatagaa gtaccatcat gatccccgca aaatagacag
    51721 cacttacgag cacgatatgc gcaacctttt ggaaaaacag tcgcggaatg ttatctaaaa
    51781 atcgattgat tttgactcct gtatgtgtga tgaacaatag aagtcccgtc ataaaaggta
    51841 gaacataata aaacaaccga taatataata gccaaactac tgctacatct tgccgaacag
    51901 acaattgact cattcctaag atcatcaaaa cgtcaaaagt ccccattcca cctgggacca
    51961 tcgtcagcat tcctatcaat gtagcaatca tgaacatagg atagatcgaa agcatcgaaa
    52021 tatctattct catcaacttg ccgatgatca aaaataccgc aagggctccc gtccattgtc
    52081 caaaggatgc cagtagcaga ccaagcaagc cttttggata aaactcgaag aacaatgtct
    52141 ttctctttag ataagcaaaa aagaaaatga ctggtgctaa aaaactaccg ccgaaaagcc
    52201 agatccaata gcttcgaaaa atactttctg actgaataaa aaagacatca ataaatgtaa
    52261 gaaacgacca tacagacaaa ccagtcagca taaatagtgc gacttttgat acagtggcta
    52321 aaaccatttt tctatttgtc tgctttccat aaaaactagc ccgcagactt gctcctacca
    52381 caccaccaaa accggcgaga ttgttgatcg tgtttgttac ccacgcagca agaagaaact
    52441 cttttctttc catttttggt tttccttgtt tttctaagac tctgatcgtc acccaatcat
    52501 acaacaacat cggagtgaca cccagcagtc cagccagaat catgagcagg atcgtcatgc
    52561 ggctttgttg tcccatcctt tgccaaatat cttgccaact catgccatta gcaatatttg
    52621 cgacttgatt tgccacaaag actaacacgg agccgaaaaa aatcagtttt aaaatcagac
    52681 tatgttcctt tatccattgc agcatcaagt atcgtttatt tttcacattt tcccattcct
    52741 aacttgtata cttttgtgtc ataccccaat gttatcttat ttattttaat ttttccactt
    52801 tagacctgtt ctttgcttgc gatgatagaa aaagaaagat atcctaatgc taaaggagag
    52861 gataacatga aagtaggatt tatcggcaca gggaatatgg cacaagctat tattgatggt
    52921 ttattaaaaa aaggaacagt ctcgaaagaa gaggtgttcg tttccagtgg acattttgaa
    52981 aatgcacaaa aatttgctgc tgaaactggc gtccatgcat gcaaaagtaa tcaggaagtt
    53041 gcatcacaat cagatatcgt tcttttagcc gtgaaaccaa aaatcattga aaaagtattg
    53101 gaagaactaa gagaatatag ccagaaagtc ttattcattt ctattgcttc aggaaaatca
    53161 ttaatagatt tagaaacagc gcttgaagat cctcaggcct ccatcgtacg tgtgatgccg
    53221 aatgtcaatg tcagcgtagg agcaggcgtt tctgcgattt gcaaaaatga agctgccacg
    53281 gaggaacagc ttcagcaagc tacgatgatt tttgaagcaa tcggcagcgt ctatccttta
    53341 gcagaatcag atttcagtac attcattggc cttgctggca gctcacccgc attcgtttac
    53401 atgctgatcg atgcgatggg acggactggt gtactgaatg gtttgtccaa acagacagcc
    53461 actgagattg ctgcaaaagc aattatgggt tcttgtcaaa aattcctttc aagtgataaa
    53521 aatccatggg aacttgtaga ccaagtttct tctcctggcg gtacaactgt tgcaggtgta
    53581 gttgccttag aagaagcagg attcatccca gcaatcatca aaggaatcaa tacgacgatc
    53641 gagaaagatc ttgagatgtt gaataaaaaa taatgatagc aatgtttttt cgtgccttac
    53701 aaaaaaagaa gagctgtggc ttttgccgcg gctcttcttt tgtatttttt attatttagc
    53761 ataatcagtt gcacgagttt cccgaataac gattactttg atgtgtccag gataatccag
    53821 ttcttcttcg attcgtttac gaatatcacg tactaaacga acagcgtcta aatccgagat
    53881 ttcttctggc ttgaccatta cccgaacttc gcgtccagct tgaactgcgt aacttgattc
    53941 tacaccggcg aagctgttcg aaatattttc cagacttctt aaacgacgga tgtagttttc
    54001 taatgattca cttcgcgcac caggtcttgc tgctgagagc gcatctgctg cagctacaag
    54061 gacagagata acagaagtag cttccacatc tccatgatga gaagcgatcg cgttgattac
    54121 tactgggttt tctttgtact tggcagctaa ttccgcaccg atctcaacgt gagatccttc
    54181 aatctcatgg tcaagtgctt tcccaatatc atggagcaac ccggcacgtt ttgctaattg
    54241 gatatcttcg ccaagctctg ctgctaagat accagctaat tttgcaacct cgaccgaatg
    54301 cttcaagacg ttttgtccat aactagttct gaatcgcaga cgtccgatga tcttgattag
    54361 atctggatga agtgtatgag caccgacttc aaacgctgcc tcttccccgt attcgcgaat
    54421 acgttcatcc atttctttac gagatttctc gaccatttct tcgatacgcg ctggatggat
    54481 tcgtccatct tgtatcagtt tttccaaggt catccgtgcg atttctcttc ggattggatc
    54541 gaatccggaa agaacaactg cttccggtgt atcatcgatg attaaatcga taccagtcag
    54601 cgtctcaagc gttcgaatat tacgaccttc tcgtccaatg atacgacctt tcatttcatc
    54661 attcggaagg gtaacgactg aaacagtcgt ttctgaaact tgatctgctg cgcagcgttg
    54721 aatcgctaat gataataagt ttttcgcttt gcgatctgct tcttctttgg cacgctgttc
    54781 agattctttt accattagag ttaactcatg attcagctct tcttcagtcg atttcatgat
    54841 gacatctcgt gcgtcctctt ttgataaacc agcaattttt tctagttctt tttgttgatc
    54901 ttcaatcatt ttttcaacgt ctttttctcg ctcttcaatt aattgctgtt ttgaactaag
    54961 tgcttcttct ttactttcaa gtgagttctc gcgtttttct aacgagtcat ctttacgatt
    55021 cagcgtttgt tcgcgttgaa tcaaacgatt ctcttgagat tttaattcta acttactttc
    55081 tctcagctca ctttcaactt cagaacggta tttctgattt tcttccttag cttctaacaa
    55141 tgcttctttt tttagagttt ctgcttcttt ttttgcacta tcgatgattc cagcagctga
    55201 tgattgtgca ccagctattt ctttctcgtg acgtgacttt gcgaccataa accctaaacc
    55261 aagaccgaca attaaaccga tgatagcgag gagaatgttg aataccataa aatccacctc
    55321 catactatct ttttcatttt tatcatctat acagcttcta tgataaatta ttctaaactc
    55381 gtcaatatgc atcttcgcat atatgtgtac aaaaaacatg cacaacttta ttctaatgtt
    55441 tgtaccccgt agtgtcaact ttaaataaac aaagaaacgg ctttctactt attcattaaa
    55501 cgatggtttt taaaataaat gacactagtt tcatataggt aaacctttaa attgagaaac
    55561 ttttctatta aattattctt tgtagatgaa cagatatttt tattttatgt acccactcgt
    55621 ataattaaat aactcacgat ttctttattc aataaaaaaa cggcaggtca aggagagtac
    55681 ctactcttca gaccagccgt ttttgtttat cataattttt attcttctac taaaggcaat
    55741 tcttcttgtc ctttttcatc ttctgggaca gcgacttctt caccaatacc ataagctgct
    55801 ctaactagag cagaaacttc tgccatcatt tcaggatgat tagccatata gattttagcg
    55861 ttttcccgtc cttgaccaat ccgatcttct ttataagaat accaagcacc gcttttatca
    55921 acaatgtctt tttctactgc catgtctaga agttctcctt cttgtgagat ccctaaacca
    55981 tacatgacat ctacttcagc gattttgaaa ggaggtgcta ctttgttttt tacgactttg
    56041 atctttgtac ggttaccaac aatatctgta ccttgtttca attgttctgc acgacgtact
    56101 tccaaacgga tcgttgcgta gaatttcaat gcgcgtcctc caggagtgat ttctggattc
    56161 ccaaacatca cgcctacttt ttcacggatt tggttgatga aaatagcgat tgtttttgtt
    56221 ttgttgatcg aaccagagag tttacgcaat gcttgagaca tcaaacgtgc ttgtaacccg
    56281 acatgtgagt cacccatttc gccgtcgatt tctgctcgtg gaactaaagc agcaactgaa
    56341 tcgactacta cgatatctac agccccactt gatactaaag catcagcgat ctctagacct
    56401 tgttctcctg tgtcaggctg tgaaagaagt agttcatcga tattcacacc taatttttgt
    56461 gcatattgcg gatctaacgc atgctcagca tcaatgaaag cggccgttcc gccatttttt
    56521 tgtacttctg caatagcgtg tagtgcaact gttgttttac ctgaactttc aggtccatat
    56581 acttcgatga tacgtccacg ggggtaaccg ccgacaccta aagcgacatc taacgcaaga
    56641 gagccacttg gaattgtaga gatttgttgg tcgatttttt cgcccaattt cataatagag
    56701 cctttaccat agctcttttc aatttttttc agtgcagcat ctaaggctgc tttacgatca
    56761 tctgccaata cgataatcct ccttatattt acaaatcaga gcaacatttc attatcctta
    56821 tcatatcttt tttagtgaaa aaaagcaaga aaaaaccgaa caaatattcg catttatcat
    56881 tttcttaaaa gctgttttct caaaagatca aatccttgca taaccgcatt atatctgata
    56941 gcagcacgat ctctggcaaa gtgatatttt tccgaaacca cgccgtcttt agatgaaata
    57001 gcgatccata ctgttcctgc agattgacct tctaacgtgt ccggtccagc cactccggtg
    57061 aaagctacac tgtaatctgt tcttgctatc tcacgtgctt gaatggccat ctgctccaca
    57121 cattctttgc tgactgttcc atattctgct aatagctccg gatcaatctc cagaaaacca
    57181 gcttttgttt ggagcgagta ggtaacgaat ccgcctggaa atacttcaga tacaccagca
    57241 atgtcgccta atgcggcttg gaaggcgccg gctgtcaaac tttccgctgc tgttacagtc
    57301 tgcttgtttt ctttcagtag ttccactacg acttttgcta gcgaattatc atcgccgtat
    57361 ccataaaaat attcccctac tcgttcttgg attttttctt ctaatgctaa aagagcttga
    57421 ttccctgcct gaacatcatt tgttttcact gtcagtcgta atgtcacttc atttggtttg
    57481 gcatatggtg cgatcgttgg attgatctgt gtctcaatca gatcttttag ctcagtgacc
    57541 agtcgcgatt caccaatccc ataaaagcgc aaaactttag aaattagttt ttcttcagaa
    57601 ggaaaacgtt cctctagtaa aggacgtact tgttccacaa acattggttt caactcatta
    57661 ggcggaccgg gaagaaggat atacgcatgt gtatctgttt gataaaaagt ccctaaagca
    57721 agccctgtac gatttggtag aggaaccccg ccttcgataa tctgggactg ttgcagattg
    57781 tttttggtca tttttcgatg ggttgtttca aaatatgcca ataatttttt gtatccttcc
    57841 gtattttgta tgagagactt accgaggtga gccgcagttg cttcttttgt caggtcatct
    57901 tctgtcggtc ctaatccgcc acataagagt atgagttcac ttcttgtttc agctagagca
    57961 atcaactctt ctaaacgctg ctgattatct cctacaactg tttgataata aacttcgata
    58021 cctagatcag ctagctgttc tgacaagaaa gtggcattcg tattcacgac ttgtcctagt
    58081 aaaagttctg ttccgacagc tattatttct gctttcatta cttcccgctc ccttatatag
    58141 tatacgctgt atttttatat ttttttattt aaaaagaggg caaggagctg tgacaaaaat
    58201 cttgtcacag ctccttgttc caaataaaca gtgttctcct gccaaaacct cggtcataag
    58261 tcacaatata cataaaacat gaaaagctgt tttttgaaat tatcccttgt gactcagagt
    58321 tagacggcag gctcacaacc tctccactaa acgatactta cattgatcct ttgaacacac
    58381 cgctgttttt gatgaagtaa tccacacctg aatagatagt aaagatcaga caagcataaa
    58441 gcatgatttg atctactgga ataccgatca ggctgaatgg gatattattg ataaacagca
    58501 agataatagc aaccatttgt gtagccgtct tgacttttcc cggccaagct gcagccatga
    58561 cttctccatg ttcgacaagt agtaaacgca agcctgtgac ggctaattca cgacagacaa
    58621 tgatcgctac tacccaacca ggggcctttc cttggtcaac caacatgata aaagcagtca
    58681 taactagcat tttatctgcc aacgggtccg caaacttgcc aaaattagtg acaaggcctc
    58741 gcgcacgggc aatttttcca tctaaccagt ctgtgatact agctaaagca aaaataactg
    58801 cacctactag ctgtgtgaca gccagtgtgg tgtctcctac gttaaattgt ccccaatcta
    58861 aaggtaaacc tacaaccaaa atgaaaatcg ggatcataca aattctaagt acagttaatt
    58921 tatttggtaa attcacacta tcgactcctt tcttccctat tctacgtgac tatcagcgaa
    58981 gtttccaccg atattattta cttttccaaa tgaatttatt caaaggagta tttttattga
    59041 aattgatctt tttgaattaa cgaagaagga ccgcgacaca gatttgtcac gatccttctt
    59101 ttttatacct acaagtaaac agatgcgtaa actaatttat acgatcattc tgcgtattga
    59161 agagtaaggt tcacattttt tggactctga ttgttttccc ctggattaac tggtacggat
    59221 tctccattcg ctttgatcgt tgcattgctt gctgcaccaa tcgtgatggt cgcatttgtt
    59281 gctgtttccg gtaacacggt actctgtgtt tcatttgctg ccagtgtccc ttgataaaca
    59341 taggcattgt ctactagcac acctaaccat acacgattga cagcagtaaa ttcaagggtt
    59401 acaggcttgg tagcgtctgt gatatttact gcgatggcac tgccagaatc ttctcctgta
    59461 gctattgcca ttttcttttc ttcacttgat tttgttgttg attctactgt agaagactct
    59521 ttggtctgcg tgctttgctc tgaggaagag gactcctcga ctgatccttc tactttaagc
    59581 gaagaagctg tgtctccgat tattggatca gcttgacgat cttgccaagt catatagccc
    59641 acgacaacga caatcgccaa agcaaccaat cctaataaaa tgacaggaag acttgtccaa
    59701 aagcgacttg gatgcgattc ttcctgatgc attgcttttc tagaagtact tactgtttca
    59761 ggctgcggac gttcagggac cgatcctgtc aatttgcttt tcccatcaaa aacatcgact
    59821 aaatggtctc catcttctcc tacagcttca gcgtattgcc gaataaatgc ccgcacgtaa
    59881 aatttaccag gcaattggtc aaaatcatca ttgtcgattg cttccaaata acgtttttga
    59941 atttttgtaa tctgctgtaa ttcatctaaa gatatttttt tattcaggcg tgcttgccgt
    60001 aatttttctc cgatggtttc aaaagccact cgttcatctt ctccagtctg tttgattctc
    60061 cgaagcatct gctgttgcaa cgaaagacgt tatgtttggg tgctgtgaca aaagtcatgt
    60121 cacagctcct tttttccgaa taaacattgt tctcctgcca actcctcggt cacaagtcac
    60181 aatatccaat aaatataaga agctgttttt tgaacttgtt ccttgtgact cggagttaaa
    60241 cggcaggctc acgacctctt tcttaaacgg tgttcaatca gctgttcctc ggtattagct
    60301 caaaaaccgg caaaatataa ggagatattt ttccgtatgt ttctctaata ctcaggtcaa
    60361 aacgctgatt tcacaacctc ttccttaaac ggtgttcaaa agcttgcatc tgcggtaata
    60421 agtccaacca agttaaaaac attaagaagc tgtttttact tggctgttct tattacttga
    60481 tgcagggcag ctttttcaca acctcttggt acacggtgtt ccagaagtag cttcttcggc
    60541 aataagccga aatatcacaa aaatttgaga agcaattttc gtaaattcct tcttatttct
    60601 tgaagctgac cacttctgtc acaacctctt tgattacttc gtttgatttt attttaatat
    60661 aagttgatta aaagagagca tgatttgttt tattttctca ctaatttttc caacacaact
    60721 aagaatacca taaaagctga ttttggagga ggttcctact acaagtctaa aacgaaattt
    60781 aagacttttc ctcataaaat actggtttat tttggtctca tgtaaaactc gctgaaggcc
    60841 tcttcactta taaatgcttc cccagctgcc agtacgtctt tcatttggat cgaatcgatg
    60901 atttcaggaa gatcaaataa agttcgatcg ccaaataaac tttgcgtaaa ttgattggca
    60961 atatattcga tcgaatttaa tgattggaaa tattgtccaa gcattttctt cttcagcaaa
    61021 tcgagatttg tttctgacac ttccggatca tcagcgaatc caagaatgat ttctttgact
    61081 ttttctgctg ctttctctgg ttcgtccgta tctccgctga agtccgcaaa gtgaaattca
    61141 cgatccaagc tgaattcaaa accaaagctg tcatcgataa ttccttgatt gtacatcgct
    61201 agatagtttc gagaagtatt gcctaaaatc atttggaaca acagattgat tgctgtttta
    61261 tagcgtaaca gttctgttcc ttcttgcggc aatgtgtcta atcctttaat accaagtaca
    61321 aatttatctc gtgtaatggc tgcttccaat gcactttgtt tgatgatttc ttttgtgttt
    61381 tcagggaaat aacgtacaat ttcttgcttt ggagggaaat tttttgcttc ttggttttcc
    61441 cgaataagtt tcatcaattt ctcaggctcc atcttaccaa ctacaaataa aaccatattg
    61501 cttggctgat aaaacgtccg atagcacgta tacaagtctt gagctgtgat tttgtcgata
    61561 ctttcaaccg tgcccgcaat atcgatatgc aatgggtgtg taggatacaa gttatttagt
    61621 atgccaaaaa acatccgcca gttagggtcg tcttcataca tttggatttc ctgaccgatg
    61681 attccttttt ccttgtttac agtttcttct gtgaagtaag gtgcttgtac aaaatcgatc
    61741 agagtcgtca gattcttttc tacctgatcc gtcgtagaaa acagatagct ggttttcgta
    61801 aaacttgtga aagcattggc ggaagctcct tgtttcccaa ataattgaaa gacatcacca
    61861 tcttcttttt caaacaactt atgttctaaa aaatgggcaa ttccatctgg aactttcacc
    61921 ttttcttttt caccataggg aataaattcg ttatcgatcg aaccataatt cgtactgaac
    61981 aaaccatatg tcttgtgata gtcattttta ggcaacaaat acacggtcaa accgtttggc
    62041 agtacttcat gataaagtgt ttcattgatt tgctcatatt ctgttttatt catttgcatt
    62101 tcctcctgct aaaaagaaga ttgcctgcaa ttcgatttgc tcagctactt gttgtatctc
    62161 tttgatcgtt acgctctcca tacgtttcaa ccattcttca tcagataatt ttgtttccgg
    62221 cagccagctg tccaaaaaag aagcttcgat tgccgcttgc ggagagtcta gagaaagcag
    62281 atattggttt ctcagcattg cttttgtctg agacagttcc aactctgtta tttcaccatt
    62341 tcgcaaactt tctaattgct cgtgaatcag atgaagtact tgatttcggt tcttttcatc
    62401 gataccggtt tggacactca tgaatcctcg gaacgtatcc acgctactag aggcataata
    62461 agctagactt tctttctctc tgacattcat gaaaagttta gagtgaggaa aaccgccaaa
    62521 taaaccgtta aagaccatta gcgcaaaacg ttctggttca tcgtaataca catttgtctg
    62581 ataagctagg ttcagctttg cttgaacgat tggctcacgt acttgtcgtt ccttcacgat
    62641 attcacttga ggttgggtat aaaacagatc tggataaact gtttcccgcg actcaaatgg
    62701 taattgccca actgcttcag ctgctttgtc cggatcaaca tcgccgacaa caaaaatgtc
    62761 gatttgatca tttgccatca tttcttgata gtaggacgct agcgaactag cagtgatctt
    62821 gtccaaatct tcgactacgc ccaaccctgg gatcttttgt tccgggctgt tttcaaaata
    62881 aagttcttgc aaggcatagg aagcaaaagt ttgtttatct tccttcaaac tttccaaata
    62941 tagacgcaga ttgttctttt ccaagtcaaa cgtcaactga tcaaactgat gatttttaat
    63001 atttggataa aataaaacct cttttaaaaa atctaccgct tgagaaaaaa ggtttggatc
    63061 attgacatat tcaccattca caaaactgat ccctgcgttt agccaatgta aatttccttt
    63121 ttttctaact gataatccaa agcttgcgcc ataaagctct gcaagttgcg cacttaactt
    63181 tgtctgatcc gaataattca aactatttgt ttccaacatg ctgctgagaa gtgaacgttt
    63241 cgtgatgact tcttgttgca gacgcgcagt aaaacggata aaaatccgga tcgttttgta
    63301 ttgttttgtt ggtaagacat gaagattcac gccttctgcc aattgataca ccatatttat
    63361 atgctccttt tcacagttga ttgcccgctt actcttttaa tgggtcaacc tgcctttttt
    63421 acttattcct ctgcttgaaa tttataagtt caggcaattc gccgtttttt ctaaatgatg
    63481 ttacacttta tagtatagca tagatgtttt ttatcaaaag aaacagacgg ctaaaagcgt
    63541 atattgtttt tttatttttt atttttcgat atactaaaga caaataaaag aagggagggt
    63601 cattcatgat caaagaattc aaagagttca tcatgcgtgg agatgtcttg gatcttgctg
    63661 tcggcgttgt tattggtagt gcgtttacaa gcatcgtaaa ccaagtggtg caaggcttga
    63721 tcacaccact aataggttgg tttgtcgcaa tgatcacagg tacttctgat ttagaaggag
    63781 cactttcaat tcttgactgg tcgccgacaa aaggcgtcac atttgcgttt ggtaacgtta
    63841 ttagtgctat cattacattt ctgatcactg gttttgtctt attcttagtt gtcaaagcgg
    63901 caaaccgtgc gaagaattta cgctccaaag aagagcaagt ggaagtggaa gaaactccta
    63961 ctgcagaaga ttatcttagt gacatacgcg atcttcttgc caaacaagtg gcagaagaca
    64021 atacacatcc agtagagcaa acaaatcttt ccgatacttc taaataataa agaatctaaa
    64081 aaaaagaaag ccgattttca gtgtcggctt tcttttttta gattcttaac ttgctacttg
    64141 ttcctttttc atgtcgatat gtggaatatc atcttccaaa tacacatctg agattgcctt
    64201 gaatccaaac gactcataaa aagcttgtag gtattcttgt gcgccgatca cgattggttt
    64261 ttctggaaaa tttttctgga tcatgttaat cgtttcttga acaatctttc ttcctaaacc
    64321 atctttacgg ttgtcctgat gaacaaggac acgtccaaaa tggatactct ccgcttcttc
    64381 atatactcgc gtgtaggcaa ggatcttccc atcagtatct tgaaaaaacg tatgccaagc
    64441 ttctccatca atgtcatcaa cttcttgata aggacactgt tgttccacaa caaaaactgc
    64501 gattcgttct ttgacgatcg cgtaaaactc tgctgttgac aattcttcaa atttctttac
    64561 ctgatattcc actaagcaaa cgccccctgc ttttttattc ttagcatacc gattcgcaca
    64621 caaaaaagca aacgaacctt acgaatctca ggctcgtttg ctttttaaac tgcttcagtt
    64681 aaaaattcga tctcaactgt ccgagtaagt acatctgaat agctgtaaga tactcgttca
    64741 aaagaatttt cttcaggatc caaatcaaca acgaatactg aaggataggt ttctgttaaa
    64801 acgccgcggc gttctgtttg acgctttctt cctgtctgag caaccaacat gattgggctg
    64861 ccgatacgac cttctaaatc tttcttgatt gaagctaaag ttgttggcat acagttcacc
    64921 tctactatca actataccac atatttttaa aattttcaag tttaccataa aaaaaaaaga
    64981 aatgcaataa aaataaataa gaagctcatt aagatttttc taaattattc ctcattataa
    65041 aatttcaagt gtttttttat tttgagtttt actctcccgt aagcgctcat tacttgcttg
    65101 tgatccattg ctaaacattc agccatgtct acaaaatcaa cgccttgcat ataataatga
    65161 aaaattttag cttctatttt tgaaaactgg atttcgcaat tttcgattgc ttcttttaat
    65221 aaaagatgct gaattgctaa aggttcttgc aatgtgatct ctgctaaaaa gtctggtcct
    65281 tctgtctcta ttttttggtc gattgagact tcatcttttt gatcacgacg cttcagcgcg
    65341 ttctgcttcc tcaacagaga atagatttga ttgcttataa cgcttttata ataacttcca
    65401 aagctaacac ctttgctttt ttcgtaagtt ctcaatgcct gatataaagc gatccttgct
    65461 tcttgttccc aatcctcaga aacataattt cttaaataat aggtgttttt caaacgtagt
    65521 aaaagtggaa aatatttttg atacagggca gcaaatgctt cttcgtcacc attacgtgca
    65581 gcgcgcaata actcctcaga cataaaataa ttcctccata aattcgttta tggaggaatc
    65641 ttatcatcaa tgattcatcg aactgattag aacgatatgt tatttatttt ttctcattaa
    65701 atcgtccaat ttttgggaca atttttttaa ctgctcttca ttccatggag aattacgtcg
    65761 gaaatcaata aaatgcatat ctttattttc ttgggctatt gttttttccg ttttttttat
    65821 cgtcttatat aattcataag cagaagttcg taatgctcct tgggaaaaga tcatccactg
    65881 ttctgctaaa tcgcttgtcg ccactgtcac ttgtgtcaaa cggtcattca gctgaccagc
    65941 gattctctcg atataactgt cagccgtttc gtcttctttc gtaaaaacaa catccaactg
    66001 gtatttctta taattttgtt ggatgcccgg aactagttgg gcatcgaaga caacgatgac
    66061 ttccattcct tcatatttcg cataatttga taaacgatgt aaaagagctt ctcttgcatc
    66121 cgccattttg tcctgctttt taagctggac aagttccggc cacgaaccaa tcatgttgta
    66181 gccgtctaca atcaacagct gttttttcat ggtctactcc ccctgacgtt gggaaaaagc
    66241 ctgatacata agcaaaccag cagcaacact ggcatttaag ctctggacgt gcccggtcat
    66301 cgggatcgtc agcaattcat ccatttcttt tttcaatcct ggactcattc ctttgccttc
    66361 attaccaatg actaaagcaa ttgatccttt ggcattccat ttttggaagt ttgtgccggt
    66421 catatctgtg ccaaataccc aaaatcctgt ttctttgagc tgttgcacag cttgtaccaa
    66481 attcgtcacg cgtgcaacag ggacatgttc gactgcccca gtggaagtct ttgttacgat
    66541 aggtgtgatt ccaactgctc ggtgttttgg tatgatcaca ccatcgacgc cacttgcgtc
    66601 tgctgtccgt aaaatcgacc caaaattgtg tggatcttcg atgctatcca aaatcaaaaa
    66661 gaaggggtct tcttttttct cttttgttcg ttcaatcagt tggtcaaggg ataaatattc
    66721 ataaggtgta atcgcaagaa cgactccttg atgcacgccg tgatcgctca aagtttctaa
    66781 tttttgttta ggaacccatt tgactggcac agcttgttca cgtgcgattt ctttcagttc
    66841 ttctactttt tctcctcgtg aatcttcttg aagaaagagt ttattccctc gcccttgttg
    66901 tagcgcttct actgcggcat ggtgcccaaa gacgaaatta tcttctaatg cttcttcatt
    66961 ttgatcagaa actgactgat ttcgtccagt ttgcttttta tttgaatatc tattttgttt
    67021 tttgtcttca aatccacgtt tcgattgatg tttgtttgtt ctttctttac ccattttttt
    67081 caccaacttt ctgaatacac cagcggatca attcttccat ccgctcggtt tgttttgtca
    67141 aatgcagata gcccatgagc gcttcgaacc ctgttgcgac ccgatacgtc gtaacatcag
    67201 cattttttgc gctcgtatgg cttttagcat ttcttcctct gcgataataa agttcttctt
    67261 cttctgtcaa aagatgttct tccagcattt gctgaatcaa aaaggcttgt gcattcgcag
    67321 aaacataatt cgttgccgca cgatgcagct tattgggttt tgtttctcct tgatcaatca
    67381 ggtggtcacg aacatagatt tcgtaaatcg catctccaac ataagccaag gctaaaccgt
    67441 tcaattgtgt gtaatctctc atgcttctct tctccatcgg gttccttgcg gtgtatcttc
    67501 taataagatc cctttttctt tcaacaaatc acgaatttcg tcgcttcgga caaaatcacg
    67561 attgcttctt gcttgatttc gttcttcgat caattgttca atctcttcat ctaataactc
    67621 ttctgctgta aataaaatac cgaagatcga aagccattgc gagaataaag cttctccttg
    67681 tgccaagaca gcggcagaaa ctttcggctg gtctagataa gtgttcagcc acttagcaag
    67741 ctcatagacc actgtgatcc catttgctgc attaaaatca tcgtccattt cttcgatgaa
    67801 tcgctgttct aaattttcta acaaagcgat tttatccgca tcatctgcca aattctctga
    67861 ggcagtttct tggcggaatt tcaaattgtc aaacgtattc ttcagtcgtt gtaaattggt
    67921 ggctgcttct ttcatcgtcg tttcactgta gcggatcgga cgacggtatt gtgtggtcgc
    67981 catgaagaaa cgcaagactt gtggatcaac gtttttgatc atttcatgta cagtgatgaa
    68041 attccctaga gatttactca ttttttcatc gtcttcgcca atcgttacat agccattgtg
    68101 catccagtaa ttagcgaatt ttttccctgt tttcgcttca ctttgtgcga tttcattttc
    68161 atgatgagga aattctaaat cttgcccgcc accatggata tcgatcgttt ctcctaaatg
    68221 ttttgttgcc ataacggaac attcaatatg ccaaccggga cgtcctttgc cccatggtga
    68281 atcccaagaa atctcgccag gttttgcttg tttccataaa gcgaaatcta atgggtcttc
    68341 tttttgctgc tgttcttccc ctgtacgctg acttgctccg acttccagtt catcgatgga
    68401 ttggtcactt aatttcccat aattttcaaa tttacgggta cggtaataca catcacctga
    68461 agattcataa gcatagcctt tttcaaccaa cacttgaata aatgctaaaa tatctggcat
    68521 atgatccatg actcttggat gcagtgtagc aggttcgaca ttcaacgctt tcgtatcttc
    68581 ttcaaatgct cggatgaaac gatcagcaac ttctggtgct gtaataccta attcgtttgc
    68641 tgtacggatg attttatcgt ctacatccgt gaaattcgat acgaaatcga ctttatagcc
    68701 tcgatattca aaatagcgtc gaattgtatc gaaagcaatg gtgctacgag catttccgat
    68761 atggatataa ttatacacag tcggtccgca gacatacata ccgacatgtc ccttttgtat
    68821 agggatgaat tcttcttttt ttctggtcaa tgtattgtag atttttatca ttctgatctc
    68881 ctcacttttt ctcctttgat tcgaacgact tttgctggta ctcctaccgc tgtagcgtcg
    68941 tctggaacat ctttcaacac aacggcacct gcaccgattt tggcgttttt tccgatcgtt
    69001 accggtccta atatctgcgc attcgcagag agcatggctc cttgtttaac agttgggtgt
    69061 cttttacccg tttcttttcc tgtgccgcct aatgttacgc catggaataa aatcacatcg
    69121 tcctcgattt ctgcggtttc gccaatgacg attcccattc catggtcgat gaacacgcca
    69181 gttccaatcg ttgctcctgg atggatctca acaccagtta ggaaacgcca gaattgagca
    69241 ttgatcttcg ccaataaaaa gagccggtgc tgatataaaa aatgagagaa acgatgccaa
    69301 aacaaggcat gaaaaccagg gtatgtcaaa acgatctcag ctgtcgaacg tgcagccgga
    69361 tcgtttctct ttgctgcatc aatcgctcgg gtaaaccaac tcatgacttt ccactccttt
    69421 cgtaagaatt ttatgtagga aatcatcttc ttataaagaa aagaagcgcc ttttaaataa
    69481 gtttccttat caaaagacgc tttccgcgtg gttccacttt tcttcataat caatgattat
    69541 ctctgacagc taacgcctgt tatacgttct tggctacttt gtttcctata aaacagtttt
    69601 tcctgttttc tgtgtttcgc caagaccact cccagaggca tttcggcaac cattcattga
    69661 taccttgcac cacccggtat ctctcttgta atgatcagct gcttactttt ttctgttcat
    69721 cgtgtttagt tcagtacttg atttaaatgt gctaatgatt tttcacgacc aagcaattcg
    69781 atcgtttcag gcaattctgg accatgcatt tgtcctgata cagctacacg gattggcatg
    69841 aaaagatttt ttccttttac gccagtttct ttttgaacag ctttgatggc agctttgaca
    69901 gttggagcat ctactacttc catttgttct agctgtgctt tgaatgcgtg gagaacagta
    69961 ggaactgttt caccagcaag tacttctttt gctgcttcat tcaatacagg atgttcattg
    70021 aaaaatagcg tagacagatc aacgatttct gcagcatagc tcatttgagg ttgatacagg
    70081 ctaacgatct tcttcaccca ttcgattgtc ttttcatctg ggttttctgc tacacgtcca
    70141 tcagcgatta gataaggcag acacatgtca gtaaatgcat ctagatccat tgctttgatg
    70201 taatggttgt ttacccattg cagttttttc gcatcgaaag ctgcgggtga tttacttagg
    70261 cgttttggat cgaacatttt gatcaattct tggtgttcga agatttcgtc ttcgcccaca
    70321 ggtgaccagc ccaataatgc aataaagttg aacattgcat ctggtagata gcctaattcg
    70381 cgatattgtt cgataaattg caagattgat tcgtcacgtt tgcttagttt tttacctgtt
    70441 tcactgttga tgatcaatgt catatgtccg aaggttggtg gtgtccagcc aaatgcttca
    70501 tagatcatca gttgttttgg tgtattggca atatggtcat ctccacgtaa aacgtgagtg
    70561 attttcatca aatgatcatc gaccgcaaca gcaaaattat aagttggcat accatcgcgt
    70621 ttttggatga caaagtcgcc accgatatta tcggattcga acgaaatagc gcctttcacc
    70681 atatctgtaa atgcgtattc tgtattgcga ggcacacgga aacgtacaac agattctaga
    70741 ccttgtgctt ctttttctgc ttgttcttca ggtgtcaagt tcgcacatgt tcctgcgtaa
    70801 tgaggcattt ctcctcttgc gcgttgtgct tcccgttctg cttctaattc ttcttctgtg
    70861 caatagcatt tgtatgctcg attgctagca agcagctgat caatcagcgg ttgatagatt
    70921 tctttacgtt cagattgacg gtaagggccg tattctccag gattttcagg agattcatcc
    70981 caattcattc ccaaccaagc aaggttttcc aactggcttt tttcgccatc ttcgatatta
    71041 cgtttttggt cagtatcctc aatacgaata ataaagtctc catcattgtg gcgggcaaac
    71101 aaataattga ataatgcagt tcttgcattt ccaatatgca ggtgcccagt tggacttggt
    71161 gcatagcgta cgcgtacttt cgtcattttc ttcctcttct ttcaaactag actttgacta
    71221 acagcaaaaa ttccgtcagt tacggcttct caaatatcat ttatttaaag ccactcagca
    71281 caaattttac cttttctaag gtaaatagta aagccaactg gttgaatttc cttaccagtt
    71341 ggctgaattt cttttttatt ttgattgttt agtctttttc tctgtctctt ttttattgtc
    71401 gattcctcgt cctgcatgtg caggtttagc aaagatcatg cgtccagcag ctgtttgaag
    71461 ggcacttgtt acaacgactt cgatacgttc attcatgtaa tgctgtccat cttctacgac
    71521 aaccatcgtg ccgtcatcaa ggtaggctac tccttgttgg cgttctgtcc cggcttttac
    71581 tactagaaca ttcatcgttt caccagggat gacgactggt tttacggcat ttgccaacgc
    71641 attgatatta agaacaggta cattttggaa ttcagagact ttattcaagt tatagtcatt
    71701 ggttacaatg acaccatcta aaagcttagc caatttgatc aatttgctgt ctacttcact
    71761 gatatcttca aagtctccat cgtacatttc gacagatata ccctcttctt tttgcaaggc
    71821 atttaggata tctaatccgc gacgaccacg cacacgtttc aaactatccc ctgagtccgc
    71881 gatgtattgt agttcgtaaa gaacaaaatt agggatcatc aaggttcctt ctaagaatcc
    71941 agtctttgta atatcataaa tccgaccgtc aatgatcacg cttgtatcca agattttata
    72001 tttatggaaa ttttctcctg attttcgttc taacagttga ctctcaactt gactagctgt
    72061 ttcttgctcg atttttttgc ttcgtgaacc aaaaactttc ttccattctt cgattcgtgt
    72121 cgttcccatt ctcaatccca gatagcctaa gatgatcatc agtaaaatcg gcaatacact
    72181 attgacgaat ggaatttcca tattgtaaag aggggtcgag atcacaacac ctaaagtcaa
    72241 tccgatgatc gcaccgatcg caccgaagag aagataagtc aagctgacct cacttagttt
    72301 ttgttctact tgtttgataa tagctgagat atgtttggcc aacagcaaag ataataaaaa
    72361 gaaaataagt gcgcctaaca ggctgttggt aaatgtatta ttcagccatc cgtttgactg
    72421 ttgaccgatt gcctgccaag ctgagggtaa aaatgaaata cccaagcttg cgccgacaat
    72481 gatcatcagc aaagtaatga cacgtttttg catcgttttt cctccgtttc gacaatcatt
    72541 tattagttag cggaacacac gcttcaacgt ttcagccaaa gttgctactc caactatctc
    72601 gattcctttt ggcgcttccc agttacctaa gttgttttta ggtaggtata cttttgtgaa
    72661 gccgagtttt tggacttctt tgactcgttg ttcaatatga ctgacacgtc tgatttctcc
    72721 agtcagtcca atttcaccga tgaaacattc cgttggctgt gttccttttt ctttatagct
    72781 tgaagcaata ctgacagcga tagctaaatc aatcgctggt tcatttaatt ttaccccacc
    72841 tgcagctttt aagtaagcat cttgattctg aagaagcaac ccagctcttt tttccagcac
    72901 tgccatgatc agagataccc gattgaaatc aagacctgtt gttgttcgtt tggcatttcc
    72961 gaacatagta ggtgtgacta atgcttggat ctctaccaaa attggacgtg tcccttccat
    73021 tgccacaacg atagcagagc cagttgcacc gtctaggcgt tcttctaaga aaatctgtga
    73081 aggattagcg acttcttcca atccatgctc atgcatttca aaaatcccaa tctcattcgt
    73141 tgagccaaat cggtttttta ctgctcgcaa aatccgaaaa ctatgatgtt gttcaccttc
    73201 aaaatataac accgtatcca ccatatgttc taacattctt gggccggcga tcgagccttc
    73261 tttggtaaca tgaccgacga taaaaatggc tatcccattt gttttagcgg ttttgagtag
    73321 ttctgcagtg gtttctctta cttggctgac acttcctgcc acacttgtga tgtctggctg
    73381 cgtcatcgtt tggatggaat caatgataac ataatcaggg gagatatgtt cgatggcacg
    73441 actgatttcg ttcatatctg tttcagcgta tagataaaat tctgtgttga tacttccgag
    73501 gcgttccgcg cgtaatttta tctgctctgc gctttcttcg ccggatacat ataagacttt
    73561 tccgcctatg gctgctaatt gctgagaaac ttgtaacagc aaagtggatt tcccgatacc
    73621 tggatcgcca ccaatcaaga ccatagaccc tggcaccaca cctccgccta acacacggtt
    73681 cagttcttct aattttgttt tgatccgagg ttctttttta gggacgacgt ctgcgatttt
    73741 tgttggtttt gctttttctc ctgtcaaact tgtccgagtt ctgcggtccg ttgtatcttg
    73801 ttcgatttct tcgaccatcg tattccattt tccgcaattt gggcagcgtc ccaagaactt
    73861 aggcgacaca tacccgcaat tttggcaaac aaattgtact tttgattttt ttgccattgt
    73921 accgcctcct tttatcctaa tcatgagaca ttaaatcaag cttaagtatc tttaacgttt
    73981 tatttactgg aagaaccaaa tccgccttga cgttgagcag tcgtttgatc ttgatctgct
    74041 tttaaaaacg gcaaaaagat cccttggccg atacgctcgc cttttttgat cactacatcc
    74101 ttgaaaccaa agttggtgaa ttggaacatg atatggcctt catttgcctc attattgtaa
    74161 taatcactgt caatcacacc tactccgttt gtcaacacta aaaaccgctt caacggattg
    74221 cttgaacggt tagcaagctg caaaaattca tcttctccca tgtaagcttt gattccagta
    74281 ggcacgaggg ttggtttcaa ttgtttttca ttttctgata catctttttt caatccatct
    74341 gcgactgttt ccaacccctt tttccagcct gctttccaga tacttggaat cacgacctct
    74401 tctgctgctt caaaatcata gccagcagca tgatgtgtag cgcgctgcgg tagattgata
    74461 ttttgatctt tatatttaga aataacttca aatcctcttt ttctcaccgg ttttcctccc
    74521 taaataaact actcctattc taacatatcc gaggctgtaa aagactttct ttacaaattc
    74581 ttcaagaaat tctgctatct taaagtaaac cattaattcg ttctttttcc aaacgactgc
    74641 aagttgtaca aaaaaactat tttttacatg actttactcg tcaaaacaag tagaatagaa
    74701 cgaaattaat gagtggatat ttgattgagg tgtcacatgc gtaaagaaat taaaaatgca
    74761 aaacgaatta ttgtcaaagt aggaacaagt acattgattt atcccaatgg aaatatcaat
    74821 cttgcggcaa tcgatcagtt agcttttgtc ctttctgatc ttagaaatcg gggaaaggaa
    74881 gtgatcttag tctcatcagg agctgtaggc gttggtatgc ataaattaca tttgtcagaa
    74941 cgtccgactt tgattcctga acagcaagct gcggcggctg ttggtcaagc cgaactgatg
    75001 aatatctata atcaaagatt cagtgtatat aatcaacaga cggcacagat cctcgtgaca
    75061 agagacgtgg tagattatcc tgaaagtcgt aaaaatgtga ggaatacatt ggaacagctt
    75121 ttgattatgg acacgatccc tatcgtgaac gaaaacgata ctgtagcagt ggatgaatta
    75181 gatcatctga caaaatttgg cgataatgat cagctgtcag ccatcatggc aaaacttgtc
    75241 gcggcagacc ttttgatcgt cctttctgat atcgacgggt tttattcaga taatccgact
    75301 acaaatcccg aggctcagat gtatcgctat atcgataaaa tcgatgaaaa gattctggca
    75361 caagcaggtg gtgctggtag cacatttgga acaggcggta tgcagagtaa attaaaagcc
    75421 gcttctagga tatttgaagc aaacagcgca atgattttag caaatggaaa aaatccggca
    75481 attatttttg atattcttgc aggaaaagaa gtaggtactt tatttaagga ggacttgaaa
    75541 tgactgactt gatgcaatta ggacaacagg caaaagatag cgcgcaacaa ctagcactta
    75601 tgcctacaaa ccgcaaaaat gagctacttg ttcaaatggc acaaaccatc aaaaagaatc
    75661 aacaagcgat cattgaagca aatcataaag acttagaaaa agcagtcgaa aacaatatca
    75721 gtgaaacgat gcaagaccgc ttgcagctga cacctgagcg aatcaatgcc atggctacag
    75781 agatcgaaaa aattgcttcg ttagacgatc ctattggaaa agtagatgag atgtggacga
    75841 acaccgacgg attgagaatc ggcaaaaagc gcgtgccact aggcgtgatc ggcatcattt
    75901 acgaatctcg tccaaatgtc acgacagatg cagctagtct agcattcaaa tcagggaatg
    75961 ccgttatcct tcgcggtggc aaagaagcat tcttctcgaa tcaattatta gtccaattat
    76021 tgcagcaagt actggtcagt gctggcgaat ctccttatgc catccagttt gtcgatgata
    76081 cttctcatga aactgcagga cagttgatgc gattgacaga atacttagat gtgctgattc
    76141 ctcgaggcgg agcaaaatta atccaacgag tcaaagaaca ggcaacggta cctatcattg
    76201 aaacaggtac aggaaataat cacgtatata tcgataaaga agcacagtta tctatggcag
    76261 tgaacatcat cgtcaatgca aaagcttccc gtccatctgt ctgtaacgcg gcagaaacat
    76321 tgctgatcca ttctgagatc gcaccttttt tcttgccagc tattgaaaaa gaactggtag
    76381 aacacggggt ctctttacgt gcggatgctc gtgcgttaga atatctagag acggctgctt
    76441 tagcagaaga cacagattgg gatactgaat atctagatta tatccttgct gtcaaagtgg
    76501 tcgattcttt ggatgaagca attgcacata tcaatcggca taatactaaa cattcagaaa
    76561 cgatcgtgac agatagttat gcggctagtc aacgtttctt aaatgaagtg gacgcggcgg
    76621 ctgtctatgt caatgcctcc actcgtttta cagacggatc ggtatttggt tttggtgcag
    76681 agattggtat ctctactcaa aagttgcatg cccgtggtcc aatggggtta aatgaattaa
    76741 cttccacaaa atatatcatt tatggcgatg gacaaatccg cgaataatgt ttcgtgtgaa
    76801 acattattcc cgccttttgc cttttttctg taaaggttct atccaactag aaaggtgtca
    76861 atatgtttga aattttaatg atttttttta tttaccttat ttctctgaat atcgctgctt
    76921 ttctgggagt cggtatttta tcccttttct ttcaattcaa aaaacgaagc atagggagtc
    76981 aacgggaaaa atggtcgcag tattttgaca aaatcgggca aaaagggctg gttacacgct
    77041 tgcacattag ttacatggtt gcattatgct tattagcgac aatcaattac tattcttttt
    77101 tcgatcattc aatcgcttat acgattacgc tactgattgc tgggattttt cacttatctt
    77161 ataaatatca gctgaataaa aaccacttga atcggacttt ccgctaaaaa atatccgtac
    77221 gataagtaga gtgccttgaa gatcggcaaa aaactgccgg actttttaga ggctgtgaca
    77281 aagattttgt cacagcctct ttttccatat aaacggcgtt cgcctaccag ctgcctggta
    77341 aatctgtttc ctcttcgtta agaagcgaaa atccgtcaaa tgtttcgcca tcataataac
    77401 gaagcagctc atccatggac aagttcatcg ttttttcttt ttcttcttcc gctgattcag
    77461 ccagtagctg ttcccgatac acctgataca taccagctat tttttgctgc atcgcttttc
    77521 tagtttcacc ttccgcattg attattggca attctttgat atagccacga taaatcaacc
    77581 gatcatctga aaattcaatg ggtaattcaa cgagtgtcaa cccgacttcc tgaaaatatt
    77641 cttccagcat ctattatccc cccattcttt ttcttaaatg aattttagct tacctactga
    77701 aaattttcca gtttcattat tttgagaaaa aaagggaatg tgacaaaaat cgtgtcacat
    77761 cccctttttc cgaataaatg gtgttcttct gccaactcct caatcataag tcacaatatt
    77821 caacaaacat gagaaactgt tttttgaaat tgttccttgt gattcagagt taaacgacag
    77881 tctcacaacc tcttggtaaa cggcgttcaa tcagctgacc ctcggtatta gctcaaaaaa
    77941 cggtaaaata tgagaagcta tttttccgtt ttgtttctct aatacttagg ataaaacgct
    78001 gattttacaa cctctgttaa acggtgttca atcagctgtc cttcggtatt agctcaaaaa
    78061 acggcaaaat atgaggaact atttttccgt ttgtttctct aatactcagg acaaaacgct
    78121 gattttacaa cctcctgata aacggtgttc aaaagcttgc atctgcggta ataagcccaa
    78181 ccaaacgaaa aatatgagaa gctatttttg tttggctgtt cttatgactt gatgcaggac
    78241 agctttttca caacctctga tttcttattc ttcttcattt gtagcaaaat aattacggtg
    78301 ataaatgata caacatacac tgataagaac aatggcacct gcaaaataaa acgcatagct
    78361 ttcaccaata tgttcaccaa tcacacctgc aataaatggt gctaaagctc caccgaaaaa
    78421 gcggacaaaa ctatagctgg acgaagcaac gtttcgttgc agacctggta tttccatagc
    78481 aatcgtcgtc aacagtgtat tgataattcc ttggaaaaat cctgctaaca caatgctgat
    78541 cggtacaagg actggcatag aagttccagc tcctaataac agcaaacaaa taatgaataa
    78601 gacaaatgct gctaaaattg tccgataagt cgtaaacttc cgctcaagag ccggtgcaac
    78661 gaaaatcgaa gcaatagcca gaagcacacc ccagccaaaa aatacaaaac cgacttctaa
    78721 ttcagaatag ccaatcaata aaaatggcgc atacgcaagt aaagtaaaga atccgaaatt
    78781 atataacaat gcgattagtc caactgaacg aagtttatga ttgcttaacg ctttgacacc
    78841 ttcccaaagg cctacttttc tctttggttt ctcagtttca ggtaaaagta ccgctagggc
    78901 tataaaaccg caaaacatca aaaatgctac cccaaaaaat ggataacgcc atgaaccact
    78961 gcccaagacc ccaccgacta gagggccaac agccattccg cagccaagtg ctgcttcata
    79021 catcatgatt gctttttctg tgttaccaac taaaatactg acgatcgttg ctaaagcagt
    79081 agagacaaat aaagcattcc cgacacccca gccggcacgt aacccaatca gcattccgat
    79141 attcccagat aatccgccaa gaccagcgaa tacaacgatg ataaacaatc ctgtcatcaa
    79201 tgtttttttc aaaccgatcc gactagataa gaaacctgta aatagcatca ccacaccagt
    79261 gactaacatg taactagtaa ataacagggt cgtttcagct ggcgtagcgt ttaactgtgc
    79321 agcaatcgtt tttaagattg ggtctactag acccactccc ataaaagcga tcatacaggt
    79381 agctgctaca actagcgctg aacttttccc ctttgtttct tcatttgttt gttcttgtat
    79441 atctatttga ttctccaata tttccatccc tttctctcta ttagcatcat acatgattta
    79501 ttttacatgt caatatgcac atgtaaaacg tggaaacttt actgtgatat aataaagaaa
    79561 ataagacgag aggtaggatt tttatgaata ctttagccta tatattatta tgcgtgcttt
    79621 tatccaaacc acgttctggg tatgaattga agcagctgat cacaattttt tgggaagccc
    79681 atcacagtca gatctataca acgcttgcca agttagacca gcagggttat gtgaccgttt
    79741 tggacaaaga cgagcactct caaaaaaaga tctaccactt gactgatgaa ggacgtgctc
    79801 ttgtagagga atggatcaaa gaggaaactc ccgctcctac gcaaaaagat gaatttctag
    79861 caaaaatcta tgctttttcg acgctcgata aaacaacagc tactggactg ctattcacta
    79921 gagaacaaca gctgaacaaa atcatgcaaa aaaatcaaaa aaaattgaat gacctctcgc
    79981 tagacaagaa acaagaattt ggacgttatg ttgtgatcca gcgcagaatt atgctttgtc
    80041 agcaggaact ccaatggtgt cagcaagtaa gagaacaaat gcagcagttt tttgagtaag
    80101 ggataaacag aacctttcta gaaatatcta ttgaagagca aattatcttc aataaaagag
    80161 caatacagtt ggaaaagaaa aagcgatccg aacgacaggc caaaacctat cgttcggatc
    80221 actatttttc tagaactgca ttcaagagac tatgacaaaa agcatgccaa ggcctttttt
    80281 caaataacag tgttccatca ttcattactt tgaattgctt ttagcacact tcttgaaagc
    80341 gggccaacga tgatcaactg caacggtaaa gcggcaatca cattcatttt ccaagcattc
    80401 atataagcag agaataattg atcaggtatt ccttgttcca tgatcacacc gaataaagac
    80461 atacatgtca ccattcctaa aaccatcaag catgaaatag ttaagatcat ttggaccttg
    80521 ctttctggat ttactggtag tttaaaggca atttttttcg ccagcacacc gatgatgaag
    80581 acatccaaaa tgaaagccac cacgaatcca ggcactagac caatcaacaa acttgataaa
    80641 tgaagatctt gatgcagcca taaattatac gcgctcatcc ccaagaccat caaaaaacac
    80701 atcattgttg taaaaattat tccttctttt ttatttgtag gcaatctgta ccactccttt
    80761 aaatttgtca cgaaaatcat cgtagcacat ttaaaaattt ctcgtaagta ctttttttat
    80821 tttctgccct tttatttcat aaacttcatc agccgtacgc tcgacaaagt aagaatcatg
    80881 agaagtaaac aaaatcgttc ccggatatat ttgcattagc ttctctaaag cttcgatcgt
    80941 tgccatatca ataaaattag tcggttcatc taacagcaac acattacttg gcttagtaaa
    81001 aagcaaagca atcgtcagac gggtcgcttc tcccccactt aatgtacata acggtttcgt
    81061 caaagtttcc tgagcaaacc ctaagtgatt cagcaaacta cggacaagcg attctgaaaa
    81121 ctctgtttgt ctcatgacaa aacgaatgat ggattcttca gatgtcattt gataaccctt
    81181 ttgctgatat acttgaaagc ttactttcgg agagagaagg attccttctc cttgtttgcg
    81241 gatatgttct aataaggttg tcttacctga accattttca ccgacaatcg cgattttttt
    81301 acctaaagaa aactgaaaat caccatttac cagtaatgtt ctcccacttc tttccaattg
    81361 gacattttgt cccatgatgg gatagcggct gtggagttca agagattttg gtactggaaa
    81421 acggatttgt ttcatctgct gcggcttggt tgtttctcct attttttgga gtcttctctc
    81481 taatgttttc gcattctttt ggatggcttt ttgtacactg tctttttgtt tagaggaaga
    81541 caaccgatcc agtctgattt gttgcttttt ctttttactg gacacttttt ccaacttttc
    81601 cgcttgtttt ttcttttctt ggatcgattt ttccaatcgt tttttctctt tcatgatcga
    81661 ctctgcttct cgtagctgag tctttttctc caattccttt tgagtgagat aggcactata
    81721 attccccgaa aactctcgga tttctccgtc ttttacttcc cagattttcg atgctagctc
    81781 atctagaaaa tagcgatcat gactaacaaa aaccagcgta ccataataat aacgaagctc
    81841 ttcaatcagt cgatcaatac tttttctatc tagatgggtt gttggctcgt ctagaagcat
    81901 cccttgttca taagaagaaa gaagacgtat caactcgatc tttcgttctt cccctccgct
    81961 ccatttccgc tctgaagttt cttccagtct taactggaaa tgactggcta attccaaatt
    82021 taggtccttt gcttcagcga gataggttaa ttgaggcagg tagttgaagg tgatctctgt
    82081 ttggattttc ccatgatcgg gaaaaagttc accggctatt agtttgagca aagtcgattt
    82141 accgacacca ttttctccta tgatccctat acgatcttgc tgatagacac gaagagaatc
    82201 aatagatagt tctagctggt tgccaaagct gacttgtaga tttgttatat ttactgctaa
    82261 attttccata tgttttacac tcctatttca tgtaaaacaa caattatcga tactaaaaaa
    82321 gagcagaaaa atctgtttgc aaaaaaactg catcacatct tttcctactc tgaacgaaat
    82381 aactatgact aaatcaccaa atctgtcata gctttcacct attctactgt cgttcgaaaa
    82441 aatggacata ctccatccat gaaattgttg tttatacatg tcttttgaat ttatttagtt
    82501 gttattcaaa agttcgaaac gtaatttcat cgatgcagtc atttttccga cctccttttt
    82561 tattaggtta ccacacacga ttcaaaaaaa gcaatagcta ctgaatagta actgaaaacc
    82621 ttttattcga acatagtgat cttttctggt gctaaacgaa cagactcgta accttcttct
    82681 accgcttttc ctattgataa aataataact ggaacataac ggtctttatc caaaccaaat
    82741 gcctctgcca actgatctgc ttcgaatcca ccaattggat ttgtttcata gccatgatca
    82801 cgcgcaacta acatgaattg catagccgct aagctagaat cgactttgac tacatcgttc
    82861 atttcttctc ttgaaaaact cttgtaataa ggaatgatcg cagctaattg ttgatctctg
    82921 acttcttttg gcatcttccc tgattcgtaa gcttggttgt agatttcttc gccatattcg
    82981 taacattgca tatcgccaaa aatcatgacc attgcagaag aagtatcatt ttgtctcgta
    83041 ttgaaacgga tcaaaggacg caagatttct tttgcttcct cgctttcagc gaccacaaag
    83101 cgccatggtt tcatattgac agaagaaggt gcagtcgtcg cttctttgat catttccagc
    83161 atttcttcgt gtgggatttt gtatgtttca tcatatacgc gaacggatct tctaccagtc
    83221 ataattgttg aaaaatcatt tttttgttcc attattatta acctctttcg tttctgttgt
    83281 tatattgcaa agttgggtat tcaatttatc taaaagtgtt agaaattgtt tcatttctac
    83341 atcgctgaaa gccggggata gcacggaacc tgtatcttta tggtccattt cacaatgctt
    83401 gattttcttc tgggcttttt ctgttagcgc tacatacact tcccggttgt tctgaggatt
    83461 tctctgacgc gaaacatagc catttgcttc caataccttc agatgacgag taactgctcc
    83521 ttgatcaatc tgcaactttt cttgcaaact gctttgtagc aatggatttt cttctttcag
    83581 tctcatcatg atctcgtatc tagtaagact tataccgata ttttcttcaa agatctggac
    83641 gattttttga tcggctaatt tgatttgata taaaaggtga ctaatctctt ctaaagacat
    83701 aatttcctcc tttctaataa ttgactcgtc aacgattgac ttgtcaataa tagaataaaa
    83761 aaagaaaaaa gtcaaagaat cagctgtgta ataaaaaaaa cgctctcaat agaaaagtat
    83821 agagaaaaga aattttttgt agaatgaacg gaaaaaatga taaagaaagc acaacgctaa
    83881 aaccaagatt attgattctt atcaaactat agaagatagc tcttctgcag tagataattt
    83941 tacaccgcca aaaatttccg aaatcgcctt ttgcaagaat cccgtcgaat attagaaatt
    84001 ggatcagtat gcttaaacag taataaaaaa gttatgacaa gatgttgtca caaccttttt
    84061 tgagtaaacg gtgttcaaaa acttgcatct gcggtaataa gttcaaccaa acaaaaaaca
    84121 tgaaaatctg tttttgtttg gctgttctta ctacttgatg cagggcagct ttttcactac
    84181 ctctttttaa taaccataaa atcctattcc ttcatatctc cagcccatcg gtgttagcca
    84241 atctctttcc ttagcactca aggtatagtg atgggtacca gttttttcat ttggattaaa
    84301 tagtcgataa attggcttgg aaccaccaga ataaaaactt agaccttcat aacgccaacc
    84361 gatttttgtt aaagagttga tctcagattg tgccattgtg taatgatggt ctccactgta
    84421 aggattgtat aaacggtaga caggttgtcc gctgtttggt gcttgccaag caatcccttc
    84481 atattcccag cctacagttg gcagataatt tttttctccg gcattcaatg tatataaatg
    84541 ttctcctgta tgacggttat acagacgata catcggagaa gttgaagttg gtgctgtatc
    84601 atactgtgtc agattatagg tttcgattac attgttcaat gtagaaccat aattaggcgc
    84661 agtggcataa cgacctgtta gccaagccgt agcatctttg taagagttcg tattgctttt
    84721 ccatgcaccg gaatagtagt aaacgcctgg ctgaaaagaa gtcgtcttca ataccgttac
    84781 gttatcttgc aatgattctt tgtacgaagg atattttcta aaagcggcat tcaccgtaat
    84841 ccattgccca ttcacatatt ccgaagtagg catcgtaaca gattggccat tatagcttcc
    84901 tttaatccca aatagattgt aattaggggc agaagccaaa gtactgttcc cccagccact
    84961 ttcaacgatg gcttgagcaa tcatgactga tgcatataag tcattggcac ttgccaaact
    85021 ttgtgcagtt gaggcaatac tatcaatgaa cgcttgttga gaattagcag atgagcgagc
    85081 ataaaaagca tagccagtat agttttcgaa ttcagacaaa tctgcttgat gggtatgtgt
    85141 caatgtttgc ccatctgtca attggttcgt gatttcttct gcattctctg gattgttctg
    85201 agcttctgct gatgtactgt cttcggtttg tgtttgttct gttgtttcag ttgttggttc
    85261 ttcggttgaa attgtatttt ctgagacagt agctgactgc aaagtacttt ctgtatcgtt
    85321 ttcaattcct gtttctgaag aactcgatgt ctgagttgcg acagtttctg tcgattcttc
    85381 agctagcact gttgtgttgg caactgctag atttcctaaa agaataacgc taaataataa
    85441 attctttgct ttcatctttt ttctcctttg aattatgaaa cttttcctaa ataacagtgt
    85501 aactaaaaaa gtaaaagcaa gtcaatgtcc atatttaaat aacatttgtt tctttttaat
    85561 aaatttgctt tttctgcata aaaagacgta aatgaagaat attcttctcc attcacgcct
    85621 taaattgatg gtcgtttgaa taactattta acaagtaatt ctctctggat attatccgtt
    85681 atggattata cttcctgtgt cgtcggacgg ataatcatgt tgctgacaga catccggtct
    85741 ggcgtttcta tcgcaaatgc tacagcagaa gctatatctt cagatgttaa tccccattct
    85801 ttttgcgctt catgaagttc aagagcagcc tttttgtcgc tgatggtttg atataattca
    85861 gtttgaacag ctcctggaga gatgatcgta gatttgatgt tattttgccg ttgctcttga
    85921 cgtaatcctt ccatgattgc acggacagca aattttgttc cgcaataaac ggcggaatca
    85981 ggataaacaa catgtcccgc cacagaatca gttgaaatga tatgcccaga tttttgtttt
    86041 tccatgattg gaagtacggc ggaaattcca tttaacacac ccatgatgtt gatatcaagc
    86101 atattttgcc attcatcacg gtgaccttca actaatggag cggttggcat gattcctgca
    86161 ttattgtaca atacatcgat tcgaccgaac ttttccatcg ctaaatcgat aactgcttgg
    86221 acttgtgcaa aatctcttac atctgctgtt tgaatatata gctcagcttc tggtaaagat
    86281 tcttttattg cttttaggcg atcttctcgg cgtgcagcta taactagttt agcccctttt
    86341 tctgctaata gcttcgttgt tgcttcaccg attccgcttg aagcgcccat gatgacaatc
    86401 actttttctg ataaatcatt cattctattc tcctcctgtt ttgaaaaatc tcttgcttat
    86461 actcactatc tcttatttca tcttactgtt caaataatcc gttcgacagg tttgacgatt
    86521 ttggcaggga ttcctgcaac gatggtattg tctgggacat ctttcgtaac agttgcattc
    86581 gctgcaacaa tggcattctc gccaatcgtt acgcctggca gaatagttgc tcctgctccg
    86641 atccaagcat ttttcttgat gtggattggc tttactgaca agcctcttcg ttcttttgga
    86701 tcggttagat ggttcaccgt gatgaggttg acacgaggac caatcaatac tgaatcttct
    86761 aaacagatgc cacctaagtc aacgaacatc acttgacgat tgataaagac atttttccct
    86821 atactaatat gtttgccgaa atctgtataa aaaggcagca gaacagtcac cgtatcatct
    86881 actttgtcac taatgatatt ttctagccgt ttgcggatat ctgctggttc atggtaccca
    86941 gtattcagcg ctgctaaagg ctcttcgttt tccgcttgga tctgatggat cacttcaaag
    87001 agcggatccg ttactcgaat ctctttattg acgatttgtt tttcgatgag gcttgtcatt
    87061 ttgctccctc cttttatcct tactttataa cggacggctt atgatgtcta atacttataa
    87121 aacatactta actattcctt ttaactatac ttagtggtat gcttttttaa aaacaggagg
    87181 gaaaaaatgg atattcgtat actgacgtat tttttagcag tagctagaga aaaaaatatc
    87241 agccgagcag caaaatctct gcatatcacg caacctactc tctcaaaaca actgaaagat
    87301 ttagaagaag aacttggtgt gacacttttc actcgaggct cccgagagat acagttgacg
    87361 gattctggtc gatatcttta ttcaaaagga aaagaaatct tgtcgttggt agaaaaaacg
    87421 gcgaacaatt taacaaatga cgcaatcatc tctggagaaa tctacattgg cggaggcgaa
    87481 actaaagcaa tctctttcat ttctgatagc cttcattcgt tgatcaaggc gcatcctgat
    87541 atccagtttc atttatatag cgggaatgca gatgatatca tagacaaact ggatagcgga
    87601 ttacttgatt ttggactcgt aatcgaaccg acaaacaaac aaaaatacca gtcatttcga
    87661 ctgccagccc aagatcgttg gggacttttg atacatcgga atcatccttt agcaaagcaa
    87721 acagtcatcc atccgcagga actgaaaact gttcctttga tcatttcccg gcaaacgtca
    87781 gtggacagtc aactagctga atggctaggt ttcagcatag atcagttatc gatcgtcgga
    87841 acatataact tattgtacaa tgcttctttg atggtcgata acgggacttt tggtgcatta
    87901 gctctagatg ggatcatcaa tacttatggg acggaaaaag tattcatccc actcgatccg
    87961 ccattacaag cttcactgaa tctcatttgg aaaaaagacc agcctctttc tcctgctgct
    88021 cgtaaatttt tagatgtcct aacggagaaa tacagttaag tagagttttt ttccttcgct
    88081 ttcagctttt taacaacgaa taagttaagc aaaagatcca atgattaaat aacataagtt
    88141 tcttaatttg ttccttcctt ttatttctga taattccagt aaattactat aattataaaa
    88201 aaagaattga caaaacataa ctgtctatat aaaattgatt acgttaacaa taattcgttt
    88261 catgtgacta gatcatacta ggcatgaaaa atctctgagg aacatggttt ccctaggagg
    88321 tttttcgtgt ctatttttgt ttggccgcaa tcaactggtc tagcaaacgt gaaaaccaaa
    88381 tcttcaaaaa gggtgcgcgc atgaaaatca aaaagatctt taatcaaaat gcagtattgg
    88441 tagatgacgg tggacaggaa aaagtagcta ttggaaaagg gattggattt gacagaaaaa
    88501 gaaatgattt gatttttgat cgtgatgtcg aacggatatt tgtcatggaa ccagaaggtc
    88561 aaatcaagtt gcaaaattta cttaatcaga ttgatgaacg ctttttattt gcagcagaaa
    88621 cgatcattga tcatgcggaa actgttttga tggaaaagtt gaatgaacat gtattgatcg
    88681 ctttgaccga ccacattgct ttttctgcgg agaacattaa taacggtatc gtcatccgca
    88741 acaaactttt aagagaaatc gaagtgcttt acagtgatga attcagtatt gctcaatggg
    88801 cagtagagta tctgacaaaa gagcttggga ttccatatac ttatgacgaa gcaggatata
    88861 tcgcaatcca tattcacagc ggacgaagcg gtcggaacaa taaccatcgc agtatccgtg
    88921 aagtgacgat tgtatctgac atcatccatt tagtggaatc agaattggaa acagatatcc
    88981 attcagaacc attttcactg aattattcaa gactggtgaa tcatttacga ctgcttctac
    89041 aacgaaccca tgcgcaacaa tatgctgttt tagacacgga aatcgtagaa atggtcaaac
    89101 gaaaataccc agaaagctat aagatttcta aaaaaatccg tgtgttgctg accaaagaat
    89161 accagctcgc gatcacgaaa gaagaactgg gttacttggc catccatatc gagcgtttaa
    89221 gaagcgcaat cgtacaaaca aatgttaaca atcatgagga ggaaaaaaat tgaaagcata
    89281 tctacaacga atgggacgtt cccttcaact tccagttgcg gtcttacctg ctgctgcttt
    89341 actagtaggg atcggaaact ggtgggcatc ttatagtaac gacattgtcg ctcatttttt
    89401 acaagctggc ggtaacgcag ttttaggtca attacctttg ctgtttgccg ttgggttagc
    89461 actagggatg tcagtggaca aatcaggtgc tgctgccttg gcaggtttgg tcgcatttga
    89521 agttccagta aatgttttaa aaactgattc agtagctact ttattgaata tcaaaccaga
    89581 atcagttgat ccatcttttg ctcagatcag taacgtattt attggtatta ttgccggatt
    89641 gattgcggca gctctttata atcgtttcca cgaagcaaaa ttaccgatgg ctttatcttt
    89701 ctttagcggc aagcgtctag tgccaatctt ggctgccttt gtcatgttgc tgatcagtgc
    89761 agtgctactg ctcgtatggc ctccggttta ctctgcttta gtttcttttg ctaaattcat
    89821 tttgagttta ggctggggtg gtgcaggtct ttatggcttc ttcaaccgtt tactgatccc
    89881 tacaggattg catcaagcaa tgaactccgt gttctggttt gacgtagcag gaatcaatga
    89941 tattggtaaa tttttggctt ctgaaggaac aaaaggcgta acaggaatgt atcaagctgg
    90001 atttttccca atcatgatgt tcgggcttcc agcaggagca tatgctattt acagaaatgc
    90061 acgtccagaa aacaaagcaa aaacagcttc cttgatgtta gcagcagctt ttgcttcatt
    90121 ctttactggt gtaacagaac cacttgaatt ctcatttatg ttcgttgctt ggccattata
    90181 tgtcttgcat gcaattttca ctgggatttc tttagcagtg agtgcattct tccattggac
    90241 agcaggattt gcctttagtg ccggatttgt cgattacttc ctatctttga aaaatccgat
    90301 tgcgaatcag ccattgatgt tgatcgtcca aggattagta acagcagtga tttactactt
    90361 tggctttaac tttgctatca aaaaattcca tctgatgact cctggccgcg aggaagcaga
    90421 tctttcagat gacgatactg caacgactaa ttcagacaat aaatatgcgg cacaagcaag
    90481 caaaatctac gctgcattag gcggagccga caatgtaact tcgatcgata actgtactac
    90541 acgccttcgt ttgcaagtca aagatacagg cctgatcgat caaaataaaa tcaaagccac
    90601 tggcgtacct ggtatgaaga tcatcgacgg aaaaaatgcg caagtcatcg taggtacaga
    90661 agtacaattc gttgcagatg agatggcaaa actacatggt ggtgctgcaa cacgacctgc
    90721 acaaacaaac accgtggtta aaacagaaac atttgccggt ggaacgatcg aacaagatat
    90781 ttacgctatc gcaaatggga aactgattcc aatcactgaa gtttcagatg atgtattcgc
    90841 ggaaaaaatg atgggtgacg gctatgctgt attaccagaa aatggagaaa tcttctctcc
    90901 aatcgctggt acgatcacaa acattttccc aacgaaacat gctgtcggaa tccaaacaga
    90961 tgctggtatc gaagtcttgc ttcatatggg catcaacact gttgacttaa aaggcgaacc
    91021 attcacttta tatgtaaaag aaggtcaaaa agtcgcaaga ggtcaattga ttgctttagt
    91081 tgatcttgcc gctattcaat ctgcaggcaa aaacacggat atggtcgttg tattcacaaa
    91141 tggcgacaaa gtccaaagct tagaaatcga acccgcacgt gatgtaaaag caaatgataa
    91201 aatcggctct gtttccaaca aagcctgagc catcgtcttc cccagacttt tttatcgata
    91261 aacaaacagg agctgagaca aaaatcttgt ctcagctcct ttttccgaat aaaaacggcg
    91321 ttctcctgcc aactccgcgg taataagtcc agccaaacgt aacatatgaa gagctatttt
    91381 ttatttgact cttcttatta cttgatgcag aacagctttt ttacaacctc tgataaacgg
    91441 tgttcaaaaa ccagtttatc ggtatgaagt caaatttatg caaaaatgtg gaaagccatt
    91501 ttcacaaaat ttttcttcat actcaaaact aatcggcttt ttcacaacct ctttatacat
    91561 tattcctgat ccaatatttc ttttaatgct gcttcaagag aagttaatgg ttttcccaat
    91621 actttttcta aatcatcaga ggaaatagct aactgatcct ttttaatatc atgttggatc
    91681 gctaaaaaca tgtcagctgc ttcttgaggg aatccggctt cttttagatt ttcgacaaac
    91741 gctgcatcac ttgcttcaat aatttctaac tttttacctg tcgcacgctc taatgccttg
    91801 gctaattctt catagtcagt tagattgccg gataattcta agatttctgg agagtcactt
    91861 tctactagta cttttgctgc agcttctgca tattcacgtt tcaatgccca acctgttttt
    91921 ccatttcctg cagcataaac gaattgacca gtttttaaag cctgcccaat gataggtaat
    91981 tcattctcta cataccaatt attccgtaaa aatgtatggg aaatacctga atccttaatc
    92041 attttttcag tgaattggtg atctggcgct aatacactga tcgagtgatc ggcatctgca
    92101 aaacttgtat aagcgatata agatacccca gctgcttgtg ctgccttcac tacattctta
    92161 tgttcggctt gacgatttcc tggaacgcca gagacaaaaa gcaatcgatc tattcctttc
    92221 aacgcttctt tcattgagtc taaatcatca taatcaccaa tacgtatatt aaatccagct
    92281 tctttcagtg cttctccttt ttcttcacta cgtactagta catagatttc attttgtgga
    92341 accatctttt ttaagaattc cagcgcataa ccaccaaaac ctccagttgc tcctgttact
    92401 aaataatgca tatttgccac tccctattct ttttatttgt taagatttac agctgtacat
    92461 ttataaatta cacctttatc ataaagagtg tggtaagata agtcaagcaa aaaaaatgaa
    92521 aggatgacaa ctgatgaagt attctctgca atttagtgat gcaatccatg tacttgccta
    92581 tattgaaatg tttcaagata cccgatcact ttctagtgag atgattgcca gtagtatcga
    92641 aacaaatgca gcaaatgtac gtaaaatcat gagtcagctc aaaaaatccg gtttgatctt
    92701 tacaaaaacc ggaaaaccgc agccttccct tgccaaaagt ccagatcaga tttctttact
    92761 agatgtctat cgcagcatcg aaggtaatac acagcttatc caagtcgatc caaaaacaaa
    92821 tccaaattgc gtcgttggtg cgaatatcca agaagcttta gaagaaagct acgctcggct
    92881 gcagaaaaag gcagaagaag aaatggctaa gatcacactt gatagtctga tacataaaat
    92941 agccgttttg gaaaaagaaa aaagaccaga aaacacaggc ctcgtagaga gatttttata
    93001 attctctcta ctgtgcctgc atttttctga tcggaatcgt ctacataaat tcttttattc
    93061 tccgggggac aaaagccttg tcatgcccct ttttcctctc taatgctcag gtcaaagcgc
    93121 tgaagtcatg acgtcttgat aaacggtgtt caagtagctg accctcggca ttagttctga
    93181 aaaatgcaaa atatggaaag ctatttccca tttttcctct ctaatgctca ggtcaaagcg
    93241 ctactttcac gacctctata ttatcatggt ttattgacta ccggtatcca gatttctccc
    93301 atatatttcc cgttggtaac tcccatttcg actacagcat ttggaccccc aacataggcg
    93361 taatcttcta cttctcttaa aacatgccca aaggccgtat tcgtcaaatc atttcttaat
    93421 tcttcaggcg attctgctaa agcgattaca acaagatacg ttccttttgg gaatgggatg
    93481 attcgggtag tgtttggaac atcctgactc gtttgaacac cgacatagta catcattttc
    93541 ccgttatagg gttcgttgac tgtaaagaaa taatgatttt cagcagcttg tttcaatgca
    93601 tctattgttc cattaccgat aactttttgc tcaaatgctt gtttctctgc agccaaaccg
    93661 acaaaatccg tattgctact cttcaattcc acaccaatac ccgtcaccgt aaaatctggt
    93721 ttttcttcga tcctatactt tgccatttct cccacccttt ctattatatt aagttcatct
    93781 tacataaaat taaagggaaa tgacacgatt acgctctttt ttctagggat atttttattt
    93841 tttaactatt tttttgcttt cactgcaatc caaatctcac tgtaaacatt actgaaatcc
    93901 tctccccatt ttgtaaaaga gatctcggga gcttcgacta actcataatc tgaagaagga
    93961 agccattctg catagatttt cccccaagta tcttgtaaag tttggggaaa tggcccttta
    94021 ttaggaaaaa tggcccaagt gtgttcttct atagcaagca tttctaaatc agcgtacgga
    94081 ttttcttttg tcgtagcaaa gccaatcatg tgcatcaaac tgcccttttc ttccaagcgg
    94141 gctccatcaa atccataaga aacgttgatt acttgatttg gatataaatc tcctaactta
    94201 tgcatctctt ccctttgagt ctccgtgatc gtctgcgcta acttttgtat ttcttgattg
    94261 actccttcaa atttgacagg aacttttttc gccacacctg ccacataaaa ctgttctttc
    94321 ttttcgatac gaaattccat cgattttcct cctctgacat caataaaaaa tgtcaagcgt
    94381 ggaaaagatt tttgtatgcc gtatctgctg atttctgaag gcagatatcc tgaccaatca
    94441 cgaaaagctc ttgaaaaacc ttcgactgtt tcatatccat atctaaacgc cgtttctgtc
    94501 actcttgatc catctaggag atcgcgatta gccaaagcca atctacggtt tttgatatag
    94561 tccattagcg acatccctgc aataaacgta aagatgcgtt ttaattgata ttcagagatt
    94621 cctgtatttt cggctattat tttataggaa agtccttctg tcaaatgttc ttcgatgtaa
    94681 tcgatcaatt ggttcagatc tttaagcata tttatcttcc tccttgcttg cctttttatc
    94741 atattatcaa agaaagtcaa ttacttgatg aatcaggaac caatttagtc agatgtagaa
    94801 aatgttgtat ggatctaaag aaaattctca agcagcgttt cgtaacggat aattggtatt
    94861 atctgcctat ctatgtttta cctttagaaa aataaatttt ggggaagaca cattctaagt
    94921 aaacaaagcg gtaaaaatat cttttattcc cttagttaat ccgcttacta cctactgtac
    94981 aaagcaaatt gttgttcaaa ctgctgatca gaacgctgct tggatttttc tttgcgatac
    95041 atcatacctc ttttatcaat tggaacaatt atttatttct aacaaaatca cttcattttt
    95101 gtcagataaa taaaaaacaa aaaaagttcc atctttaaaa cacgctattc ttttactttt
    95161 tctcacattc tctaagaaaa gaaaaggaga atgaattttt gacaattcga gcaaaagtga
    95221 ttatcaaata tgtaaaatca gctacttttt tcttaaacgt ttctttatac taaatataaa
    95281 taagtgtttc atgaaaggag aactagatga ataattggct tgagtatttt cctgaaaacg
    95341 ttttggaacg cggttacagc tatcatctgc acggttttgt ccgtcatttg aactatacaa
    95401 gcaagtactt gtccgcaaca gtttctggca cggaagatta taaggtagtg atcacttggg
    95461 atgaaaagac caacatgact tgtgattgtc tatatgccat agaaggaaaa aaatgcaaac
    95521 acatggctgc tgtcttattc gcttacgaag aacgtccaat aaaaaaatcc aactactcac
    95581 tttccgaact ctcgtccctt gtttcctccg ctagttcctc tcttgtacgg gagcttttaa
    95641 cagagattct tatagaacat ccgcaattta tcgaacgctt caaagttaag atgccatttc
    95701 atgcaataaa ttattcagat aaattaacaa ctatcatcca taaatacgat catattatca
    95761 agaaaaacaa aaacaggaaa acagcgaagt tcatcatgga gatgcgaaag ttcatccaag
    95821 aagcagttga atcgctcatt cagcaaaatg cctatcttcc cgcattcgaa ttgatcaatg
    95881 aagtgattgc tactctcgaa acattctatt gggagcctga ggatgaacga acccttcttc
    95941 tgatagagga ctgttattat ttatggaaag aattattagc agaagcacct catgcagaaa
    96001 aaaggcaaat gttctcttgg ttcgtctgcc aagtcgatca tactgacgcc tcttattcaa
    96061 aacgctactc cataaaaatc ctgaaagaag actttcggga aaaagaattt tctaaccaaa
    96121 agaaaaaaat agataaaaaa actaaagaaa cggtaaagaa agacgatttc aatgaaaaat
    96181 agcaagtaaa cgataacaac catcctaaat ccacaagaaa tacagcagac cttgctttaa
    96241 aaacacgaat catgcaaagg atgaagtaaa gaagacttaa cgcgtaccca atattagtca
    96301 tttgactatt aggtacgcgt tttgttttat aagtcatgac aaatttcctt cgttgctggg
    96361 tagattttcc ggcattgttg atagatttta tgatactttt ctacattttg taagagaggt
    96421 tccactgcat ctgtatattg gataaaattc tgacaacaac tttcaggtgt gtcgaaccac
    96481 tctaatcttt aaagataaat attaaaataa cgattaataa tattaacagt ctttattttt
    96541 caccaccaaa aacctatctt tgcatatact aaatagacgt atatacacag ataggtttgt
    96601 cttgtgaaaa ataatgatta tccttaccaa aaaatgtttg tttttctaca tgttcgtact
    96661 tatcaaaaaa tatgatcctt attgaaatta ctggctattt atattccaac gacttcttgt
    96721 gttaattttt gttatctcat agtaaattat gtttcatttt cacttaattt agttgtcacg
    96781 tgttcgtcaa ttcgtaaaaa cggtaaatat ataaacacac ttgcggctat aattaatatt
    96841 tgtaaaacag ctgctcgcca gtctccggct gttgctaaaa atcccgatat aactggtggc
    96901 gtagtccaag gaatttgcac tactacatga ttaattaatc ccacagcagt tgcaaaatat
    96961 gctactgtca aagaaaaaat cggtgcaagc acaaagggaa taatcagact gatattaaat
    97021 acaataggca atccaaaaat aataggttcg cttatattga atatagcggg agttaccgat
    97081 aatttagcaa agtccttata atcttttcta cgactgaaga taaatattgc aatcaataaa
    97141 gcaatcgtat ttcccgatcc acccattacc gcaaaggtat ctttaaaggc catattgata
    97201 atatgtggaa tttgctcttt gtttgcataa gctgccatat tttcttgcat attctgaatc
    97261 aaaaacggat ctaacaatga acctgatatt actgcttgat ggataccaaa tccaaaaaat
    97321 agattagcaa tagatgtaat taacaaaaat cctggtaaac cagttgtaat tttacttaat
    97381 ggctctgtaa ctatcgtggt aattagctta tttatatcca tattaaacaa ttgaatgatt
    97441 ataaatgaca ataaagcaaa cgaggtaatc gtaataatga ttgggattaa tacattaaaa
    97501 gactttaaaa cagcgggagg aatatttccg gatagctgaa tctgtagttt cttattatta
    97561 gaaagtttaa taaataattc tgtagccgct aatccaacaa atatacctac aaacattcct
    97621 gaagctcctg tataggatat aggtatcaca cccgtcactt caacagcttt atccgcattt
    97681 tcaggagtaa acatcatctg cataggtgtt aatacaacaa atgtcgaaat agcaactaat
    97741 accgctgcaa tatgatttgt ataatttctg cttgcacaca tatgataaga tactgctgct
    97801 acaactaata atgtagttat gcttaatgta ccattggcaa ttgaagtacc aatttgttgt
    97861 aacgtggtca atgtactagt atcgacaatt tcccccatga atcctgttgg ttctaagatc
    97921 actgaattaa taagtgtcac aaatcctgct aacatcataa atggcataaa tgtagcaaac
    97981 gcatctcgca aagttcttaa atggatctga ttccccaact tagtcgcaac tataccaaat
    98041 ttttcaaata caatgtcctt cctgctactt ttgcccatat tttttctcct ttatgcttat
    98101 tgtaatcgat tactttttcc acccaaataa tacatcactt atcaaaaaaa gtaaatactt
    98161 ttaattaaat atatatatct tttttagtat aaaaaaataa gctctgaaaa aataattttc
    98221 ccgagcttat ttttcaacaa aaacagcttc aaaaacaaag tcttgatata aatgtctcga
    98281 taccgaatac tcgaaaggtt taccagacga tagagcaaca actttgtcta tctcaatcat
    98341 aaattcacct ggatctattt ttaatatttt tgcgtcaaat tcattcgcag tatctccttt
    98401 gatacgtatg tgcgaagtct ttatttccag acccagttca tttgtgatat aagcatatac
    98461 agatttcttt aaatgttttg gttccaagcc tggtatgact gctaatggca tgaatgtttg
    98521 ctcaatcgag tatggttgac aatcaataaa acggcttcgt acaatattat atacatagtc
    98581 ttttacactg atacttaatt tatcagctac ttttttcgat ggaagttcaa ttgagaaagt
    98641 atggatttct gaatctacgt gttcttcacc aaccacgcta aacaaacctt cgtttggacc
    98701 aagaactcgt gagttatcaa ttggtgttct gacgacttca gtcccatacc cacttctact
    98761 tcgcaaaact ccttcggaaa caagtaagtc tacgcctttc tttactgtta acttgcttgt
    98821 atgataaata actgccaatt catctcctgt aggaagtttc tcaccaattt tatactctcc
    98881 atttacaatt tttttcttta tatctaagta aatttccata tacttcgcaa tttttttcaa
    98941 tggtgaccct ccaatcaaaa acatatcttc atctatactt taacataaat aaaccgataa
    99001 aatccacatc aaaattatac acacaataaa aaagatatat atatttaaac aaaactattt
    99061 actttaagtt gtaagcggtg ttatcattaa gtggaaacag gaggtaaaaa aattatgaca
    99121 actatgaaaa agctaacttt tccagatgat ttttggtggg gttccgcttg gtcagctgag
    99181 caagcagaag gaaaaggaga aacaggaaaa gcagagacta tctgggatcg ctggtttaaa
    99241 gaacaacctt accggtttta tcaacgaatc gattcctcta ttacaaccga tcacatccat
    99301 caatataaag aagatataga actaatgaaa aaaactgggc ataactcctt tcgcgtttct
    99361 atttcttggg cacgaatgtt tccaaatggc ggtaccggaa aagtaaatcc caaagccatt
    99421 tctttctatc gaaaattatt ttccgaaatg aataataacg gaatcaaagt atttgccaac
    99481 ttatatcatt ttgacatgcc tgctactctt caagataaag gaggatggga atcacgtgaa
    99541 gtagttgatg cttatgttca ttacgctgaa acttgtttta aagaatttgg tgacttagtt
    99601 tgtcattggt ttaccttcaa tgaaccactt gggcctattt taggtactta tcttgaagat
    99661 tttcattatc caaacctcat tgactttaaa cgcggagcgc aagcagcatt cttcactata
    99721 cttgcacacg caaaagcaat acaagtattt aaagaactag ctcttcctag taaaataggc
    99781 gttattctaa atttgagtcc tacttttcct cgtagtcaaa atcctgctga tgtgaaagca
    99841 gcagaaatcg ctgatttatt ttatacgcgg agctttttag atcctatggt taaagggaat
    99901 ttttctaaaa agcttatcct gttattacaa gaatataatc agcttcctga agattatacg
    99961 aaagaagatc ttgtatgtat ctacgaaaat accgctcaaa ttcttggact aaactattac
   100021 gagccacgtc gcgtcaaatc tcgttcttct atggtggata catctagtcc atttttacca
   100081 gagtggtttt tcgaaccaca tatcatgcct ggacgacgaa tgaacgaata ccggggatgg
   100141 gaaatttacg aaaaaggaat ttatgatttg tgcatggata tcaagaacca ttatggaaac
   100201 atcgaagcat ttatctcgga gaacggaatg ggcgttgcgg atgaagaacg tttcatggat
   100261 gatacagggc aaataattga tgattatcgg attgagtata tcaaagatca tcttgcttac
   100321 ttatggaagg caataaatga aggatgtaac attaaggggt atcatctttg gacatttatt
   100381 gattgctggt catggatcaa cgcctataaa aaccgatatg ggctggtttc actcgacctt
   100441 actactcaaa aaagaacaat taaaaaaagt ggcgaatttt acaagcaatt aagtgataca
   100501 aatggattta gatacgatgt agacttgtta gttgaataat attctaaaat tccacttgaa
   100561 gtgaacacat tagaaaacaa gaataatgag aaataccaat aacaaatact ttttcttcat
   100621 acttcattta tacttgtcag tataagagac tgtgacaaat gtagtgatcc tcagaagtta
   100681 ggtctggaaa tctaacttga gaagattttt ttaaactacg tccagtcttt tttatttgtt
   100741 taaaattgaa gttgacaagt cttcattaaa aatttagaat attcacaagt ttgacgacaa
   100801 ttatgaaaat ttatgtcgtg ctaaaggagt tttgttattg gatgaaaagt tagatataaa
   100861 aactgcgatc aaagacacgt tacctaccgt ttttggttat atcggtattg gacttgcatt
   100921 tggtatcgtt gggaaagctg ccgggtttca tccgctggtc gtcacgttga tgtccctgct
   100981 gatctatgct ggttctgccc aatttatcac ggtcagcatg cttgctagcc atagtccact
   101041 gctctccatc gttctctcga cctttctagt caattcccga atgattctga tgagtatgac
   101101 gattgctcct tatttcaaga aaaatcggct gcttcaaaat ctgctgattg gcacattgct
   101161 gacagatgaa agtttcgcac tgggaatgaa taaattgaac tatactggac aaaagttaaa
   101221 ctttcgttgg atgaatacag ctaattggat ttcttatttg acgtgggtgg gttcttctct
   101281 tgttggcgca cttttaggga attttattac tgatccgaaa aagtttggtt tggatttcgc
   101341 catcgtcgct atgtttatcg ggttacttta tcttcaagtc atttctgata gaaacacctc
   101401 taaacgatta cagttgatcc tgattggtct cactttgatt ctggtatatg tcggactgat
   101461 ttttatccca agtaacttag tgattttagt tgtaacactg attgggtgcg gattgggggt
   101521 gtggatcaaa catgccttct tttgagttta cattgctgac tattttaggt tgtactttag
   101581 caacttggct ttctaggatc ctaccatttg tcttactgaa aaaattcgat ttgccgcaac
   101641 cgttgcttga gtatttaagt tttgtcccga tcgtcattat gtctgcttta tggttcagca
   101701 gtctatttac ccaaaatatc ggacatctgc cgcagatcaa tctcgaaaat gctttggctt
   101761 cagttcctac acttttagct gctattcttt caaaaagctt attggtgatc gtcttggtag
   101821 gaattctttc cctttcgttg attcgcttat tataaataaa aaaacaagag cttatggcaa
   101881 attactgtca tgcgctcttg tttttatcaa agtcaaataa gaaaaaaatc ggcgtattct
   101941 tgcttatccg ttgaacggac cactaacaac gacttttcct aatatatgtc ctgtttctac
   102001 gtctttggtt gcttgtttca agttcttcgc attcatccca tctgaataga ccttgctcaa
   102061 tgtactgcgg ataatccctt catttgctaa agcagcaatg tgcgctaaag cttctccttg
   102121 cgtttcgatt tcatagttat agtctgtttt agcgaacata tactcccagt cgaagctgat
   102181 agattggttt ttccaaacac ctatatctaa cggctctttg atccctacga tcgttcccac
   102241 atgtccaaat ggtcggacaa ggtgtttgat ttgatcaaag tagcgggtaa tatcgaataa
   102301 tacagcgaca tactctactt gatcgattcc taattcacga aaacttttac ttaagtcgtg
   102361 atgataatcg attggatagt ctacacctgt ttttttcagc cattcaaaat tcttcggact
   102421 tgcagtcgcg tagacttcta ggccagccca atgcgctagt tgattcaaaa tcgaaccgac
   102481 gcccccagct ccgttgatca ctaagatttt tttcccgcgg ttggcatttt cttctggagt
   102541 cagaccaaat ttttcaaata acaattcata agcggtcaat gaggtcaacg gcaaggctgc
   102601 ggcttcttca tctgaaagat tttttggtgc aagagcgaca atacgttcgt caaccagttg
   102661 gtattcttga ttgcttcctg ctcttgtcgt tgtacctgcg taaaaaacgc gatcgccgac
   102721 agaaaatttt tgcacttcat cacctacagc aacaactttc ccgactccat caaaccctaa
   102781 gatacgtaaa gcatttctta tcccgttatc ttggcgaagt ttcgtatcga caggattaac
   102841 agatactgcg ttgactttta ccagaagatc ccgtgaactg ggtacaggta tctgttcttt
   102901 ttcatcaata aagctttttg gatcatcgat cgacaaccct tcataaaaac cgactacctt
   102961 cattaattcc ttttctgaca tacgaattcc tccttagctt catcaagttg gagcatccat
   103021 acagttttca tttcaatata tatagtatgc tatttgttcc acttttattc atcataatta
   103081 ttctcttact taaagtaaac tatttgcact tttttggtta aaaaagaggt tgcgacaaga
   103141 cttttgtcac aacctctttt aaacggtgtt caatcaactg accctcggta ttcgctcaaa
   103201 aaacgacaaa atatgaggag ctatttttgt ttggctgttc ttattacttg atgcaggaca
   103261 gctttttcac gacctctaat tcacggtgtt caagcaagaa atcattgttc actgaaaagc
   103321 gttggatgtt ctttttcaaa ggtgtctaag atctctcgta cttcatcagt agatttcgta
   103381 ttcatcaact gaactcgcaa gtcatttgct cctggaaatc ctttgatata gattttaaag
   103441 aaacgatgta gtcctgtgat ggaacgcggg atgatttctg aataatgatc ttgcagatct
   103501 agttgcagac gaagtagtcc gatcagttct ttttctgtat gttccctcgg ttctttttca
   103561 aatgcataag gattcttgaa aatcccccgg ccaatcatga tgccatctac gccatatttt
   103621 tcggccaatt cttctcctgt ctggcgatct gggatatctc cgttgatcgt gatcagtgtt
   103681 tgcggagcga tttggtcacg taaagcaatg attttaggga tgacttccca atgtgcatct
   103741 actttactca tctctttacg cgtacgcaaa tggacagaaa gattggctat atcttgatga
   103801 agtaggtgac tgatccattc ttccatctca gacatttccg tatagccgat acgcgtcttg
   103861 acgctgacag gcaaaccgcc agctttagcc gcttcaatca attgtgccgc tacttctggg
   103921 cgaaggatca agccactgcc ttttccacgt tctgctacat tagggactgg gcagcccatg
   103981 ttgatatcga ttccttggaa gcccatttct gccatagcaa tgctcatttc tctaaaaaat
   104041 tctggcttgt ctccccaaat atgggcaacc atcggctgtt catcttctgt aaaggtcaat
   104101 cttcctcgta cactgtcttt tccatctgga tgacagaaac tgtctgagtt tgtaaactca
   104161 gtaaagaaga catccggtgc tgctgcatgc tttacgacat ggcgaaatac aacatctgtt
   104221 acatcttcca ttggtgctaa aacaaaaaaa ggctttggca gctctttcca aaaattagta
   104281 gtcatttatt tgttactctc cattctatca agcagtgaag tcgcaatctt tctcaaaaac
   104341 attgtcatta tactaggaaa caaaaaaaga agcaaagtga acagcttaaa agatgtttct
   104401 gattgagcaa aaaaagactg tgacaaaaat cttatcacaa ttccttttcc ggaataaatg
   104461 gtgttcaaaa gcttgcatct gcggtaataa gtccaaccaa acgaaaaata ggaggagcta
   104521 tttttgtttg gctgttctta ttacttgatg cagaacagct ttttcacaac ctctccacta
   104581 aacggtgttc aatcagctga ccctcggtat tagctcaaca aacgacaaaa tatgaggaac
   104641 tattttcccg tttgtttctc taatactcag gtcaaaacgc tgatttcaca acctcttttc
   104701 taacttctca atcctcttcc tttattgatc aaataccaag taacggcgta caaaacaacg
   104761 atgaatagca caagtacgat catcgatgtt gctactggca catcgattgt tccaaggaat
   104821 ccgtaacgga aaccgaagat catataaacg atcggattga ctttcgaaac agcttgccaa
   104881 aatggcggca acatagagat ggcatagaaa acgccaccta gataagttaa cggctgcaag
   104941 acaaatgtag gcacgatcga tacatcgtca taagactgag caaaaatccc gttgagcagt
   105001 cctgctaacg aaaacaagat tgccgtcatc aataatgtaa tgatgaccat gaaccatgaa
   105061 tacacatgaa gtggtacaaa gaacaaggaa atgatcgtta cgagagagcc gacgagaata
   105121 ctgcgaccca ctccgccaat cacaaagccc caaatgatca catgcgtagg aacaggcgct
   105181 accaagattt cttcgatgtt tttctggaat ttttgagaga agaaggacga agaaacgttg
   105241 gcatacgaac tagtgatagc agacatcata atcaaaccag gcacgatgaa ttccatatat
   105301 gaaaaaccac ccatgtcacc gatccgacca ccgatcattt ttccgaaaat aacaaagtac
   105361 aaggatgtcg tgatcacagg cggaaccagt gtttggaccc agatacgcaa atagcggttc
   105421 gtttccttga tagctaaact ttttaatgca gtaaaataaa gattaaacat ttttctcctc
   105481 cgtatgatta ttttcttctg tgattttcaa aaacagttct tctaaacgat tcgacttatt
   105541 cctcatagaa agaactttga ttccttgtct tgtcagctga tcgaagattc cgttcacccc
   105601 ttgatttcgt tcaacttcga cagcgattgt ctgttcatct tcaaatgtac aagcgtatcc
   105661 ttcaatcaca ggtttggtct catatggcgc taaatcaaag ataaatgttt caaattgcag
   105721 tttggataga agctctttca tactagtatt ctcgatcagt tcacctgatt ggatgatccc
   105781 gatgttgcga caaagcattt cagcttcttc taaataatgc gtcgtcaaaa tgatcgttgt
   105841 accattttcg ttcaattctc ggagaaactc ccacatctcg cgtctcaatt caatatcgac
   105901 tcctgctgtt ggttcatcca agatcagcaa acgtggttca tgcatcaatg ccctagcaat
   105961 catcagtctt cgcttcattc ccccggaaag catacgtgca cggacatttc tcttttccca
   106021 aagattggac tgcttcaaat atttttcgct gcgtttcatc gcttctttgc gagagacacc
   106081 gtagtagcct gcttgattca cgacgatttg ctggaccgtt tcaaagggat tgaaattgaa
   106141 ctcttgcggg actaatccaa tctgttgctt tgctcggact agatccgtat ccagatcata
   106201 accgaagaca ttcacttttc cagatgtttt attgactaaa gaagtaatga ttccgatcgt
   106261 tgtagacttc ccagctccat ttggtcctaa tagcgcatag aaatctcctt ctttcacgga
   106321 aagatcgatt cctcgcaatg cttcgacccc acttccataa acctttttca aattatttat
   106381 ttcaagcgca tttgccattt atttcctatc tccttataga catgattctt tattgtatca
   106441 tggaatacag cagatgaaaa aacaacttgg ttccagcgaa aaatcaggtt gctgggctca
   106501 ggaaaatctc ctaatgaaag acatcaatcg gacgaagtca gacaaccttt tcagaaaaaa
   106561 caaatcgaag ataaaggatt actattcata tgtgcaacaa aaggagcgtg agacaaaagt
   106621 aaagaacact tttgtctcac gctctaaaca cgtataaacg gcggaagcaa aagccaagat
   106681 ttttgatcca ataaatactt tcgatcactt cgcctatccc aatacatgcc actgccgctt
   106741 ttcatcaaat aacgcggctt ccgtttttgc ggtttctact aaagtctctg ggtaatccaa
   106801 aactttcagc aaggcaatcg catttcgggt ccttgaaggt ccttctttta atttgaaatc
   106861 aaaactgatt ccttttcctt ctgttacttg ttcttcaaag tggacattct cacaataatt
   106921 ctttaaaatc tctgtcaatt cgatatcatg tgtggcgaca aatgctaaag atggatactc
   106981 cgcaagccac cgaacgactg aagcggaaga agcaatccgt tcgatcgtat ttgtcccttt
   107041 taaaatctca tctacgaagc agtagcagcg ttctttggaa gccacttggt ccaacaaacg
   107101 tttgatcgat ttgatttctg aaacaaaata actgtcgcct tcaaataaat catcttcgat
   107161 tgccatggaa gtcaacacat gtccaggttg cagggtaaac tgttctgcaa tcgctgtttg
   107221 gatcgtctgt gctagaatac agctgatggc tatacttttg acatacgtag attttcctga
   107281 tgcattggaa cccgtgacta atgtattctt ctgccagttg accggattca ctaccgcttc
   107341 ttttaacaat ggatgataga tatctttcgc tgtcacaccg ccctcagtaa actctggtcg
   107401 gcaagtgatg ggcatataag tacggtaatt caatattgca gcggctactt ctaattctcc
   107461 cagcaattcc cacagcttga tggcttcagt tgaatgcttt tctaatttag tgagaacgaa
   107521 atgataggag ataaatggca gcatgaacat gatgttgaca tattcaaaaa tcaactctgc
   107581 ttcactccca ctcttcatac gaaatgaaaa acctaattta gggatgtctc ttaatggttt
   107641 agtttgctgt ttcagctctt cttgaagtgg tgtcggcagt tttgctagct gattggcggc
   107701 tgaaatcgtt gaaaccaaat aactcatgct attcagctct gtttctagtg tttgtttctt
   107761 cactagataa tagaccgtat tgaatactaa cccaccgatt gccaaataga ttcctagtac
   107821 ttgtcctaaa agaagcaaac ccaaacccac cagcggaagc aagccaagaa aaataaataa
   107881 acctacgcgt ccaatctttt tactttttcc atccgctaga tattgttttg caaaattatg
   107941 atcttttttt cctaaacgag cgaattgata ttggattttt tctctcagtt gaggattttc
   108001 ctgataaaaa gcaatcagtt tttctaactg ctgatcttca ccaaaatcaa agctgcgtaa
   108061 acgttgatac aacgcttctg aacctacact agaataggta ctgttgattc cttcgaatac
   108121 ttcgaacata tccaggtcat accaagtaag atcatcgatt tcgctatccc atgaacggaa
   108181 cttcttctcc gtgagccatg cttccttcaa gctttcttct ttatcaaatc tcggttgata
   108241 aggaattttt tcccatttgc tacgaactgt ttcctttaat ttcaaacgtg aaaaaatgtc
   108301 taaagcaact aataaaataa cagctgcaat aataattaaa acgataaatt ctctttgacc
   108361 catatccctc tccgttcctt tatttgttag ctttagtata gcactgttgc gctatttgaa
   108421 aagagggtaa aaaaacacct ttcaaaataa aaggtgtttt tttcttgtat attacatatt
   108481 tatctctcat ttatcaaaat tgacaaataa tcatagggag gaattgttgt taattcttgt
   108541 ttattctcca gtgcattgac aactgtccca agggaaagga tagcctcagg tactattttt
   108601 tcttgttctg ttggattagc taagcgaaga acaaatcctt gttcatgaaa ataagaagga
   108661 taaatcgatg atacaattaa gtcttcaggt aattcaatca atgaaaattt acgaggaaca
   108721 tcaagttcat tttgtaatgg ccaaatcttg ttatctaacc tgtgaataaa tacattcagt
   108781 ttctgctttt gataagaaat agattgttct aaccgttttt ctgcctgttt tgccactttg
   108841 aactcattaa atcttccttc ttctacatta aatccaaaag tgactttata ctcacctatc
   108901 tcttgagcta gcggtgtttc catcatgaca tgcccttcat ttgtcgtatc tcctgaagct
   108961 cgcccaggtc gccaagcaag attaggtttt ccaagttccc ctgttgttga aaataaggtt
   109021 atgattaatt gattttctat acgttcatac tcttttaaac catctgcata aaacgtaaaa
   109081 taatgatcat tttctgccac agagacactc ttatcgaata tttctaaatt aacaggtttc
   109141 tctaccatag tttctgacca attcggagga atgacatcag gggtattttc aataaatccg
   109201 ttttgaattt gtgcaattga tttttcagat ttatctaaaa cattaattgc taagcgcata
   109261 cgatgcgagt aaacagtatt atgaattttg agtgtgcctt caacgatttg actttctccc
   109321 agactgaacg atatttcata agatatttct tccatttcgg gtttttcaga taaacgatct
   109381 tttaaatctt taggaagttg agcttttccg taaacaacta atgtttcttg taaagaatct
   109441 ttatatactt tagctgtttc taattttaga gatagttctg tatctccttc taatggtgaa
   109501 taatcatacg tatcgccatc atttgctgaa tcgatcaaat gaacgaaatc aagatattgt
   109561 ctatctccaa ctatcaaatt caattgccca tctttaaaag aaagtttata tttattgtta
   109621 cttatctcag ttttgtctat ctcgattgct gtttctaatt tttcattatt tttctcaaat
   109681 tcaacaacag tgtatcctag tgctggcaca tttacattta tttttatgtc aagttcataa
   109741 taagctggtt catcaaaata ttcgaaacct gtagcaatca tccgataagc atttttccgt
   109801 tctggaaaat aaacttcttt ttcaatgata ttatagggac tacctttgaa gtgtattttc
   109861 tttgaatcag ctactacatg cacgattttc gatccactat aattctcagt cgttgtgttg
   109921 aaaacaagga cttcattcga ttttagcttt aatgcatcag ccatccgttt tacaataagg
   109981 ttttcgattc cgtcagctat ctcattagct tctttgattc gatggaaaat atcttccgca
   110041 acattatctg aaacacagcc accaatacta tcatgagcct ggttttgcaa aatctttttc
   110101 cataaccgac gaagtaggcc tttactgata tggataccat ttctttctgc aatcagcatg
   110161 agcggctcaa ctcgttttag aattttttgt tccaatttaa aattttctat tttcattttt
   110221 gttcttactg agccaataga acgatgaaca cgagagtaaa ccggctgacg aagttcacct
   110281 ttatattcag gtaattcttt tttgtttctg ataacttcta cataagaagg ataatctgaa
   110341 ataatattgt ggaatttact gtatttattc aacttctcta cgacttgatc aaaatttaaa
   110401 atcattgact tttgatctac acccgaaggt actaaaatat ctttgttttt tccttgcata
   110461 tgaagcattt caactgcttc atccaacttt tcttttgcaa attcaggaat atctttaatt
   110521 gcgtctaagg tcatcattcc agtcatataa ccaaatggaa aattcatggc ataaacaaat
   110581 ttatctccca atcctttcca gataaaataa ggagatggaa ccatcgtttc aaagtttaat
   110641 cctcgccaac acatgaaatt atcgatttct acttgatgca aaagtgtagg caaattcgca
   110701 ttgaacccaa acgtgtcagg caaataccct accatcattg gatctccata tttaaggatc
   110761 gtatcactga ttccaatcat taagtttctt aaaattgatt cagcatccac taataaggca
   110821 tctgtttgtg cataccacgg tcccacgaat agttgtcctg ttttcatcag tcgttggata
   110881 accttaagct tttgcggatt gatctccaaa tactcatcga cgattgaagt ttgtccatct
   110941 aaacaaaagt ttactttagg gttcctttcc aattcatcta gaacttcagt aaagacctga
   111001 tcagacaata cgatggcatc ttcatttgta aaataccatt ctctgtccca gtgcgtgtgt
   111061 tgaattatat gtgcatttac catatcagat tctcctactt tccttcttct actgaattta
   111121 cttgttgttc ttttttatac ttgatggatt ttagtgcatt gaccattaac gctgtaacca
   111181 ctcccccaat aacaattgat actaaatata aaggtatatt cgtaacaaaa ggaattgcca
   111241 taaaggttga aagcattgtt tcttgagtaa caccaaaaaa tccatttaga ccacatgcta
   111301 ctgcagtgcc caccacgatg cttggtatta ctcgtaaagg atctttcacg gcaaacggga
   111361 tcgtcccttc agtaatcccc acaaggccca taatcatagc tgtctttgca ttatctcgtt
   111421 ccgattcatc ataaagtttt ttgtttaaaa ttgttgctaa aaacattcca aatggcggaa
   111481 tagcaattcc taataacatg gctgtactag gtccaaagct tccgcttgaa aaagaagcaa
   111541 ccccaaaagc atatgcgatt ttattgatag gtcctcccat atcaaacgcc atcattcctc
   111601 ctaaaatagc cgacatcaaa gcagcatttg ctcctgacat gccttctagc caattagtca
   111661 gtcctgttgt cattgcttga ataggcgtag ctagtacata ccataatatg attccaacaa
   111721 ctaatgtagt aacaaaagga atcagcataa ttgattttag actaataact tgcatcggta
   111781 cttttacttt tttcaatgca ttagctaaat agccacaagc taatccagca accattcctc
   111841 caataaatcc cataccaaga ttttgacaca tcatcccagt gataaaagct ggtgctagac
   111901 cgggacggtc agcaattgaa tatgcgatat aggctgaaat catcggtacg ataaactgta
   111961 atcccgtctg accaatcatt cgcaggactc cccagaatgt atccgtctgg tcccaaacac
   112021 ctgtgccacc aaaaatgact gcaatagaag ttagtaaccc tgctgctacg acaagcggga
   112081 tcatatagga aaccccactt tggaaatgat ttagaatttc tcttccttgt ttcttgaatt
   112141 ccattagtaa ctcccccacg atatattttt tatttgttaa ttaatgcaat tgcttcatca
   112201 atcgtctctt caccatcttt tactacctct gaggtcccta ctgttaaaat cggtttaccg
   112261 tcaaagcgac ctcgttctga aacatttgta tctactgcaa atatgacaac atctgcctcg
   112321 gaaacatccg aaattgaaag tttgttttct atccccatag ccccctgtgt ttctacttta
   112381 atatctaacc ctttcttctt cgcaaacttt tctaaattag cttttgccat ataagtatgg
   112441 gcaatccctg cgatacatgc tgttactgct actatttttg tcatatgaaa ttcctccttt
   112501 taaaatgata gagcttttac caattctttt ttatttctcg aatcttttat tcttttaaca
   112561 aactcgtcat ccatcaatct tccagataat tctgctaaaa tacgtaaatg attagtacct
   112621 ttatcagtgt cttttattgc taacaaaaag acgagatcaa ctggttgatc atctaatgcg
   112681 ccccattcaa cagaccgctt taacttggct acagccactg ttgattcaat tactgctagg
   112741 cttttgccat gaggaatggc gatatttttc ccaattcctg tggtcatatg gttttctctg
   112801 tcaaatacgt ctttttgaaa ttgtttgtgg tcagacacaa acccattagt ctctaacaat
   112861 ttcgataatt tttcgactac acttttttta tcagatgcat ttaaatctat cactatatta
   112921 tttatattga ttttttcact gatcatttat aagccttctt tcaatatata aactaatttt
   112981 tcaaacgacg aactcgtttt taaatttgct aataactcat gattcgaagc gatttcattg
   113041 aatgtttcat aaattttatt caattcaggt tttacttttt cattaagtgc aaaaaagaaa
   113101 acagaatgaa caagtgtccc atcccaatca attccttctg gattaacgta gacacagatt
   113161 actggctttt ttataaaatc tacttcgata tgcggcatag caaaatcatt catcgctgtt
   113221 gaagatagtt tttctctttt gattgctccc tctagtatcc cttctttcgc gtaattttct
   113281 tttaccaatt ttttggtaat tatatttaaa acgttcactt gattatcctt tatttggtgg
   113341 gtaaaaaagc aaaatcgttt atctaataaa tttagaaaag catcttctgt ttgttcattt
   113401 aactgtagat actgttttac ttttctgaca tctgccccta acatcaaagg actaacaaca
   113461 ataacaggaa aatttgtatt ttcaatcgga atcgtgctta taacaagttc atcagtgact
   113521 tttctatctt gtagttcatt gatgcttagt acatcttcta tctcaaccat atctgcaaaa
   113581 ccgttattta ttctttgctc taataatttt gatgttccat atccgctact acaaactaat
   113641 atcactttcg ttttgtcagg tttgtaacga tccaaaagtg attgaatatg gagtgttacg
   113701 taagcgattt catcttcatt aaaatgtata cagaatctct cttcgatttc ctctaataaa
   113761 tctacactta tcataaatga ccttttaaaa gaatatttga ttttgtccgt ataagggtta
   113821 tagatattta ctcccaattt gagtctttta actgctgcat tgagatgtaa tactagatta
   113881 ttgatcaatt cttcatcagg ataaaattca tttaatttaa ttcttactaa ctcttgtagc
   113941 tcaacaccca tatctaaata ggaaagcttc gtttgatcta agtcgtgatt catagcattt
   114001 ttttcaatcg aagtaatgtg aatgtcaaca taagcttgtt catctattgg cacaataatt
   114061 gaaaatgctt tttcaatcat tttgattaaa ataagtgtat tctttgagat ttcttcttca
   114121 gaattattac tacgtgataa gaaattgctt gtttcaatcc tttctatcgc aatagcaagg
   114181 tggatagcta aagtttgaaa ttcataatct gtaaatttca attgtgtctt attcatgtat
   114241 cgattaagca attcggctac ttttttcaat atgtccttat ttaagaaatt attcgcttca
   114301 ccaatgaaat tgatattcaa gtctaagaga tctgttttac tgttagatgc tgtaaagcca
   114361 ccccaataat agttcacaac ttctgacatc aaccttcttt tacttttttc atcagctttg
   114421 atgcgcacgc catttcgatc tgaaactaag gacatcccat gcttgtttag tctttttcta
   114481 acatctttca ttgtgctttc taccgtcgac ctgctcacgt ataattcgtc agcaagattt
   114541 tgaatcttta gagaatcatt agtattcaat aatttagcaa acacataagt tagacggtcc
   114601 tccggagagt ctgcgatatt gattttatga ctggataata aatttcgaag tgtttctttt
   114661 tttccaataa gcgaaacgcc ttttttaggt tgaaccaaca tttgtacatc tggcattttt
   114721 tggattattt ctttcaaaat taaaatatct ttgctaattg ttttcgtaga tacatataat
   114781 tgttctgata attctttgta agttgtgtgc tcattttcaa tcaaaaagta tagtattttc
   114841 atttgccgtt cgctaaattc gatgcccatt atcttcacct cctgaataca gcttaagtgt
   114901 acaattatta tctctatttt catacagaag aaagttcttg attaatgtag aagtttctaa
   114961 tattcttgat tatttcaaat caataaaaaa gcctgcaata tttatatcac aggctttttt
   115021 ctctattaaa tatatataag ataatacatt tttctactag ttctcactaa tcttgtataa
   115081 ttaaaccctc cgcaacttga cggagatgga gaagatgccc ccgtctaatc tagcggtcat
   115141 ctctcctccc attccttcca ccaatttttt tgacaggtaa agcccgattc cgctagattc
   115201 cgtatttgtg cggctggtat tttcggtata aaaacgctgg aagacttttt caacagaggt
   115261 ttgcgttcct ggtttgatag gattggccac tgttaatcga atgaatggat cctcttttga
   115321 aaatgtcacc tttgcttgtc catctgcata acgcaataaa ttctgtatga tattttgcag
   115381 cactcgcagc aacatgagcg gatctgctaa tacagttgta tttatcgagt gttcagcgaa
   115441 cgctacctcg atatttttct cagaaaattg ttcataaaaa gagaaaaata cttcttccac
   115501 ctctttagaa aaagaaagcg tatggagatc catttctttt tgcttcgtct ctattcgagc
   115561 aagatcataa aactgatccg tcatactgag taatcttgca acagattgtt tgatgatcgt
   115621 taaatacttc tcccgtttct ccgtatcctc tacctgttcc agtaattgta cataaccgtt
   115681 aatagcagtc aaaggagttc tgagatcatg agaaaggccg acgatcgata gtctgatgtt
   115741 ttcttccatt tcttgaaatg cttgtccttt ttgttcattt tcatccaacc atgtattcag
   115801 tgcatctact aggtccatta gattcttttc tcgaaattcg actgaaagac gaccaccata
   115861 ttcttgtcgt tcagaaagag tggcgatttt cttagttaat ctcttgattt ccctttgcag
   115921 gaagaaaata aaacttccca taaagataac aacgagaagc aacagccatt taatcaaatc
   115981 taaaccccac tccccacacc gtatgaatat acacagcatg tgcctttgct agcttccctc
   116041 gaagattgga aatatgcata ttcactgttt tctcactatc aaaatatggt tcttgccaaa
   116101 ctgtttcata aagatttgct cgcgaaaata cttttttcgg atgttctaaa aaaagcttca
   116161 gcagatcgaa ttctcttcct gtcaaatgga cagccacacc attcacattt acatccctcg
   116221 actctttgtc cagtaagatt tccttgtaat agatgcgttg cgacagatct tttacttgga
   116281 cagaagtctg atgacgaagt tggatgccga ttcgtaacaa aagttcttcg atatcaaatg
   116341 gtttcgtcac atagtcatcc gctcctgctg ccaacaagga aactttatct ctttgatcgc
   116401 tttttgctga aagaacgatg atcggaacat tcgatgtctg tcggatttct gctaacaatg
   116461 cttcacctga aagccctgga agcatgagat ctagaaggat caaatcgaca ggatatgtgc
   116521 ttaacaataa ttttccttcc gtacctgaat aagcatcaag aagtttgtat ctctgttcaa
   116581 gaacctcctc cagtaaggaa tgaacagctt catcgtcttc gataatcaaa atagtttcca
   116641 gcaggaccac ctacttaatg tcagattttt ggaaaataaa cattcctaga gctgatgata
   116701 ccacgattgt tactagactg accagaatca ttttcggtgc ttgcgaataa gttgcttgtt
   116761 gcgcaaagtc cgtatacatg agccacgttt ccgtaaacca ctccgttaga aattccaagc
   116821 ctttgatttt tgcgaaaaca ccgggaatga aggccgttcc catgatataa agaaaagaaa
   116881 gaagcaaact gacactggta cttctagtga tgaatgtcaa agccactgga acagataatg
   116941 tccctaatgt cagcagaagc aatacaggaa atacttttag aacataattt ccatagtttt
   117001 tgattccctc aacttcacca aatccgaaag caagtgtgta agcaagcatg gctagtcccg
   117061 tgatcaaaac cacgccaagt gttgtgatca aaagcgtaac gagaagtttc gacacataat
   117121 aagtcattcg attccgtcct aaagataacg tattgcgaat cgtaccgttt tgaaattctt
   117181 ccccaatata aaagcacgca aatgctgcga aagccagaag aatccatgca gccatttttt
   117241 ctaccattaa aatccctgtt gcaccgttga tgactgtatc cgttgcttgg tttaattcat
   117301 tgccgtattt tgtatgcata taccattcgt tccaagaata aaaaagcgga agtacgacca
   117361 tcagtcctag tgagacccac attttacggc tcttccatac ttttattttt tcagcagtta
   117421 atagattaaa catgtggatt gcctccagtt aattgtaaga aataatcttc cagtttttgc
   117481 ccaactaggt gaataccatc cacaggaact tttgcttcta ccaatgcttg attgatggct
   117541 gctacttggt caattccttc aaaaagctgg ataacacggc tagattgtac aaaataatcc
   117601 ctataaccaa gagagtcgag aaccgttact gcttgttccg tcgccgaagt gtcaattttt
   117661 ataaattgac gagattcttg tgccaattct tctttcgata attctttgat caagtgtcct
   117721 tcatgcaaaa taccatagtg agtggcgatc tgtgacaatt catctagcaa gtggctagaa
   117781 agcaagacgg tgatgccccg ttcttttacc aaacgttgga tgatttctcg catttctgcc
   117841 atccctgctg gatccatccc attcgtcggt tcatccaaaa tcaaaaattc tggattcgtg
   117901 atcagtgcat ttgcaatagc taaacgctgg cgcataccta aagagaaatt ctttgctttc
   117961 tttttccctg tattttccaa tcgcatcatt ttcagcaggt cttcgatttc tctatccgac
   118021 acaccgccgt tcgctgcttg gatacgtagg ttatctcttg cagttaattc tggataaaga
   118081 gcaggggttt caatcgattg acccatacgt cgtcttgctg cctgcaaatc cgtcgttcca
   118141 aataattcga tcgaaccttc atcaatcgag atcaaaccca taatagttct cataaaggta
   118201 gacttacccg ctccattttc cccaatcaat ccatagatca ttccacgttt gatttcgatt
   118261 gatactttat ctaatgcttt ggcagcaccg tattttttgg ttataccagt tgctttcaag
   118321 accgtttcat ttccaaaatc catacttatc cttctttctt attgatgagt gaagtatagt
   118381 tgacgggtat aaagaaagca gccagaaatg tataaagaaa gtgtaaattt tccaattgaa
   118441 tgtcaaaaaa aacaatcgga caatacgtgt ctttcctatt atcaggcagt ttgttatacg
   118501 cttgtatcag tttcctgatt ctttcttttc gaccaaagtc gtttctctgt attcctcttc
   118561 actgaaaatt tttgcttctt tcagatcaag cttgagtaat tttaccagac cggttataag
   118621 gataactata gcaagactcc ctcccagaaa aattagactg tctcgcagac gtggttgcgt
   118681 tgtcttccaa tcaaagagcg caccaaacag tgctaatcca agtggactgg ccaccatggt
   118741 aatcgttgtt atcgttgaca taagtcgtcc ttgtatatgc gttggaactt ctcgctgaag
   118801 ccagaccata taaaaagcaa aagaaaacat taatccttaa aaacggactt atgaaaaata
   118861 atacatgccg tttgggattt acaattagct accaaataag aggttatgac aaaagacttt
   118921 tcacaatccc ttcttccgaa taaacggtgt tctcctgcca actcctcggt cacaagtcac
   118981 aatatttatc aaacatgaga agcaattttt gtaaattcct tcttatttct tgaagctgac
   119041 cacttctgtc acaacctcag aagcggataa ataatattgt ttgatgatac tttatctttt
   119101 tcccgtttgt ttatagatcg aatgatatta tagaccaaga atcctaccta ttaacatagc
   119161 taaaaacaca aaaaaggcac tttccaaatt gtggaaagtg ccagaaaagt taggattaag
   119221 gtaactgcgc tcagcattgc ttcgcccagt acgattctcg taactcgtga actcgaacga
   119281 taatcgcaat taacgttttg agaactgtga agctttacgg gctttcttaa gacctggttt
   119341 tttcttcgta tcattgaata agtttgaaaa accttgattt ataaaggttt tcccgtaaat
   119401 atattttatt atatttgatt aaatttgaaa tgtttgtgtt ctaaaatgtg ttctaattta
   119461 aaggcagtat atttcgtatt ttagattaaa tttttaggct cattcattct caaatccatt
   119521 ctattcagtc aataaaaatt ttaaaaagac tttataaaca aagatgttca agcgagcatc
   119581 ttattttttt gtgcttaatt tgaaaggaga acatttcatg tataaaaaac aaaaaaagaa
   119641 attatgtgta ttaactattt tgagtttggc tgttcaagca attgttggag caattgctcc
   119701 tacgattact tttgctgatg aaattaccca tccacaaacg gtaaccgtag aactagattt
   119761 agcacatcaa tatgctgttg aaggaacttt tagtgatggt cgtccaatgt cagaagtcac
   119821 tgttccgcat tatgcagtgt acaacggctt taaacaagat attttctgta ttgaaccagg
   119881 agtcccgatt tacaatgagt tcactcctgg ctatgagaaa aacccgttac cagatatgtc
   119941 cgataaagcc aaattagttt ccgttttatg gaaaaaagta ggtacagatg cagatactca
   120001 tattgtggca cagaagatga tctggcaaga agttaatggg tatacccttc actcaataaa
   120061 acgatcagat ggtagtgccg taaatatcgc agccattgag gcaaaaataa atcaagccat
   120121 tgacgattat cagaagaaac caaccttcca taatagtacg gctaaaacag tattagggca
   120181 atcgactact gtgacggata cgaataatct gaatttgtca gagttcgatg aggttgtgga
   120241 aaatgccgca aacattgatt atcgtgtgaa tggtaatcag ttgataatca ccccaaatgc
   120301 caattcaaaa gaaagtggtg tgctgacgct taagaaatct gctggtaccg gaacacctgt
   120361 cgcctataaa aaggctggcc aacagacttt aatggccggg gcgattgata aacctaatac
   120421 ctacacaatc aaaattgatg tggaaacgga gggttcttta aagatcaaaa aagtcgataa
   120481 agaatcgggt gatgttgtac caggaacggt tttccattta gactttggaa aaactttacc
   120541 tgcaaaagac gtgactactg acaaagaagg cattgctaca ttggatgaga ttcctcatgg
   120601 tacaaaagta accattaccg aaaaatcagt accggcgcct tatacgattg ataccacccc
   120661 catgactacc accattaaag caggcgaaac catttacgtg acttcaaaaa acgcacggga
   120721 aaaagggcaa atcattctgg ataaaagcgg agttgaaaca gggagtgatc tttggaatga
   120781 caattattcc ttagctggta atacgtttgc cattcgcaaa gacagtccaa ccggtgaaat
   120841 cgttcaagaa atgaccacgg atgaaaacgg tcatgcggaa acaccaaaag agattgctaa
   120901 tgcgttggaa ttgggaacct attatgtgac cgaaactaaa gctagtcatg ggttcgtgaa
   120961 tacgttcaaa cctgtaaaag tcgaattgaa gtatgccaat caaaccgtag cccctgttac
   121021 cagtaacgta aaagggcaaa atcaagaagt cactggcgaa accactttga cgaaagaaga
   121081 caaagatact ggggataaag cacaaggtaa ggcagtcttt gagggtgctg aatacacctt
   121141 gtttactgct aaggatggaa aagctgttaa atggagtgag gcttttaaac cagagttagc
   121201 gaagggaacg aaaggttctg atgaaacggt cactttgact ttagacgaaa agaaccaagt
   121261 tgccgttaaa catttagcta tcaacgagta ttattgccaa gaaacaaaag cgcccgaagg
   121321 atatagcctt gatgaaacaa agtatcctgt atccatcaaa aaggtggatg atagcgaaaa
   121381 aaatgccgtg attacccgaa atgttacggc aaaagaacaa gtgattcgct ttggctttga
   121441 tttctttaaa tttgctggat cagctgcggg cactaccgaa actggcttca atgatctgac
   121501 ctttaaagtg tcgccattgg aagggaccaa tgaaatcaca ggtgccgaag atgaagcgac
   121561 cacagcttat aacgagcaat tagggtttga tggttatggc aagtttgaaa atcttcctta
   121621 tggggattat ttacttgaag aagtagaagc cccagaaggt tttcaaaaga ttacgccatt
   121681 agaaatccgt tctactttta aggaaaacaa agaagacttt gtgaagagtg agtatgtctt
   121741 taccattacc gaacaagacc aaaaacaacc aattaaaacg gtgaccgttc cttacgagaa
   121801 gctgacgaac aaagcatttt ctgttagttt gaaccgttta atgctctatg atttgcctga
   121861 ggaagaagat agtttaactt ctcttgcgac ttggaaagac ggaaacaaag aattaacttc
   121921 tctggattct accgagctag ttgataaatt gagttacaat ctacatgaaa tcaaagaaga
   121981 ctggtatgtg gtagcgcaag ccattgatgt ggatgcgaca aaagctgccc aagaaaaaga
   122041 tgaaaaagcc aaaccagtgg tgattgcaga aacaagcgca acgttggcga acaaagagaa
   122101 aacaggaact tggaaaattc agcataaatt aaccgccgaa caagttttaa ataaaactat
   122161 tgtcttattc aactatgtgt atgaaaataa ggaagctttt gaagcaggcg ataagccagt
   122221 agcgaaggat gttagcttga ataaccaagc ccaaactgtc agttgtacag tggaacacca
   122281 tgtttctatc caaacaaagg cccacctaga aaacggttct cagaccttta ctcatggtga
   122341 tgtggtggat atgtttgatg atgtgtcgat tactcatgat gtactggatg gctcaaaaga
   122401 agctttcgaa acaattctgt atgctttatt accggatggt acaaacaaag aaatttggaa
   122461 atctggcaag attgattatg aagtaaatga taaagaattc accaaaactg tgcttgcgaa
   122521 aaaagtagat accggaaaat atccagaagg aaccaagttt acttttgcgg aaatcaatta
   122581 cgataaagat gggaatatca atggaaaaca caatgaagat ttgaaagaaa aatctcaaac
   122641 cttaacacca aaagaagttc caaccatact aagtacgccg aaacaaccgg aaacaccaac
   122701 tgttccaagt ggctctcaag aatctagtcc cacagtgaag accttccctc aaaccgggga
   122761 gaaaaattcc aatgttttac tgttcattgg ttttactttg atttttgcga cggcgggcta
   122821 ttatttctgg aatcgccgga actaaggtga tgagatgata caagtaaatc ctaagaacca
   122881 acgtgcgcga ccgcctccta aaaaagtagt cgcgctattt ttgtatccaa aactaacaat
   122941 gaaaagagga aaagaagatg gaattgaaat ttgtcgtgcc agatatggct gaaacctttg
   123001 gaaagttaag ttatgccggt gaaggagaaa ttataacaga aggatatgga cggaatacta
   123061 cggtgattgg tcgcagttat catttgtatt ccagtaagca acgggccgat gatattgagg
   123121 tggtagtagc tgcggaagcc ggtgaaaagg attttgatca agaccaaccg ctaaaagccg
   123181 tgaatcccca tttggttgcc aaaggctatg agattgagaa tcgtgggttt actgattacg
   123241 tgttgtatgt tgatgattta gtgaaagcat aggaggaaaa gaagatgaga ttaacagaag
   123301 gtattgtcgt agattcaggt ttaacatttg ggaagttgcg tttttccgca ttacgccgag
   123361 aagtacggaa gcaaaatgag gatggaacaa ttggtaatga ggtaaaagaa cgaacctata
   123421 atttaaaatc ctctgcacaa gggcgaatga ttcaagttag tatcccagct aatgtaccct
   123481 tacgcgagtt tgcttatgat gcagaggtag agttggtcaa tccaatcgtg gataccgttg
   123541 ccaattatgt ttttcgagaa ggaactaccg ttaattggtt cattaaggcg gatgatttag
   123601 tcttgaagcg gcagccgaat caaggaaatc ctacgaacca aaatgaaaga aagaaatagg
   123661 tgaagattat ggaaattaat gttgaacata ttttagattg tctcgatcaa tatggaaaag
   123721 gcgagctgac tgaggaacaa ctcgttaaag cattaacctc tgatgaaaaa atgtttctga
   123781 ttatacatca aggtttactt ggagaaaata gcgacagtga agaagactct gatgtactag
   123841 actggttagg agaagaagag tctttcttta tagttgtcga agtaaatgaa aacttatgtc
   123901 ggcaggcaga atccattttg gaagaaattg gtgtggagat gccggatgct attgaaggct
   123961 ttttaaatca attggttgaa acgaaacaac tcccctcctc gtagcagtaa atgactagca
   124021 taactttttg aaattgccta atgaaatcct attgggcttt ttcgattgga ggtggaaacc
   124081 atcaaaatgt acaaaggaca tcgcatacgc gcaggagatc agcacttggt ttatcacttt
   124141 gttcttggct ggctactcgc tctgttcatc ggttggatga gcgtctttta ttttcaagag
   124201 tttagacaat ttgatatttc taagctatca ctttctacta ttgaaatcgt ttggtctata
   124261 aaagatttag tatgtctgct tggaagtctc gctttttcag gagctatgat attgctttat
   124321 attcactttt ttcttgatca ttggcgaagc ttgtggcatc gacaaaagct agctcggatg
   124381 attctagaga accattggta tgaagtgaaa caaactcaaa gtgaaggctt tttcaaagat
   124441 ttgaatagta gccgaaccag agagactatc agttacttcc ccaaaatctg ttatcgaatg
   124501 aaagatggat tactgtctat tcgcgttcaa atttcacttg ggaaatacca agatcagctt
   124561 ttaaaattgg aaaagaagtt agaaagcgga ctgtattgtg agttagtaga aaaggaactc
   124621 aaagactcct atgtggagta tactttactg tatgatatga tcgccaatcg aattgggata
   124681 gacgaagtag tggcagaaaa tgggactctg cgattgatga aaaatcaagt atgggcttat
   124741 gattctttac cccatatgtt aatcgctggt ggcacgggtg gagggaagac ctatttcctc
   124801 ctcaccatta tcgaagcact attgaagtca gatgcagaat tgtttatcct cgatcccaaa
   124861 aatgcagatt tagctgattt aggtacggtg atgcctcatg tttattcaca aaaggaagaa
   124921 atttctgctt gtgtggaaga tttctatgaa cgtatgatgg ctcgtagcaa ggcaatgaaa
   124981 gaaatgtcta actacaaaac aggagagaat tatgcctatc ttggacttcc acccaacttt
   125041 ttaatctttg atgaatacgt ggcttatatg gagatgttaa cgacgaaaga aagtgcggtg
   125101 attttgaata agctcaaaca aatcgtgatg ttgggtcgtc aatctggttt ctttctgatt
   125161 ttggcttgcc aaaggccgga tgcgaaatat ttaggagacg gaatccgcga tcaattcaac
   125221 tttcgcgtgg ctttgggtcg tatgagtgaa ctcggatatt ccatgatgtt tggggaggtc
   125281 gaaaaaaact tctttatgaa gcacatcaaa ggtcgaggtt atgtggatac aggtggcagt
   125341 gtgattagtg agttttatac gccacttgta ccaaaagggt atgatttctt agattcaatt
   125401 agtaaattag aaaagatgaa tgattgagtg atcttcaata ctgactttat acttcaagta
   125461 acgtataata cttttatata gtaggaagaa aggggataat taatatggaa agtaatgatt
   125521 cttatttaga gtatgcaaaa gcaaataagg ataagtttat ttcttatatt atcaaaggga
   125581 aatcccccga agttggacga gacgcagttt ttatggcagg gagtcctggg gctggaaaat
   125641 cagaggttgc cattggatta gctgagaatt atgataacca tgtgattatt gatgcggatt
   125701 actttcgcac ccagtttcct gattataatg gaaaaaactc tagtctcttt caaaaagcat
   125761 cttcttggtt ggtagagcag gcatttagat atgtcttaga tcatggctat tcttttattc
   125821 tggatgcaac ttttgcaata ttaagtgctg aaaaaaatat ctcgcgggcg ttgaaaaaac
   125881 attttcgagt gacgattttc tatgtttatc aagaccctaa aatcgcttgg aaatttacac
   125941 aagaacgtga aattgcagag ggacgtcatg tgccgaaaaa ggcatttatt aacgcttttt
   126001 tcaaatcaag agagaacatt gcaaaagtaa agagtaaaca tccagatgta ttgcttcata
   126061 tcataataaa agattatacg aataatattt ccgaagttca ttatgctacg gataatctag
   126121 aattattttt accactaggg tatagtagga aagatttgga ggttcaatta catgactgag
   126181 aaagaacaag taacgaaaat tgtaaagaaa tacaataaga gcattgcgga tttatcggaa
   126241 aatgctactg caaaagagtt caaaacggtg attaaatatg tagccgatca ggccaatgaa
   126301 aaacaacgga aattagttgg attaaataaa aaatagtagg acaaattaat aatgtatgag
   126361 ccaagagcaa aatgttcttg gcttttttct ttgcaatgaa tgaggtaatg tatgagattt
   126421 ttagatttat tcgccggtat tggtggcttt cgtttaggta tggaacaggc gagccatcat
   126481 tgtatcggtt tttgtgaaat tgataaattt gctagacgta gttataaagc aattcatgat
   126541 acaagtaagg aggtggaaat gcatgacatc acaagtgtat cagatgagtt tattcaatcc
   126601 ctcggaccag tggacatcct ttgcggcgga tttccgtgcc aagctttttc aattgcggga
   126661 aagcggcaaa gattttccga tactcgaggt actttattct ttgaaatcgc tcggttcacc
   126721 actcttctcc gacctaagct tttattcctt gagaacgtcc gaggattgct caatcacgaa
   126781 ggaggggcta cgttcgagac gatcctccga acgctggatg gattggggta tgacgtggag
   126841 tggtaggtgc ttaactcaaa ggcctacatt ccccaaagcc gggagcggat attccttatc
   126901 ggacattctc gagacgcatg taccgaacaa gtatttccta tcattggacc gtcttcaaca
   126961 tctgatcaaa acatcagaaa tttggtaaat atcaatcctt ccaatcgagg aatgggtgga
   127021 caagtctatg gttcagatgg cgtagcgcca accttaacag gtgatgaagg aatcaaaatc
   127081 gcactgccag caagggatgg aatctctgta gcaggactat taccgggaaa gtttgaacaa
   127141 ggtaatcgag tttatgaagt tactggaacc gcccccacct tgtcaacgaa acaaggtggt
   127201 acaaaaatca tgattcgaaa aaatgaaaca gaatatcaag aggtgaagcc agaagacagt
   127261 gtgaatctgg cttttcctaa ttccacaagt cgccgaggtc gtctgggaaa acagagtgtt
   127321 cataccttac taacaggaga ccaacaagcg atcgtcacgg atcagtatca aattcggaag
   127381 ctaacaccta gagagtgttg gcgacttcag ggctttcccg attgggcttt tgatcgagat
   127441 tctcaagtca attcagatag tcagttgtat aagcaagccg gaaactctgt aacagttccg
   127501 gtcatttttg atattgccag aagattaaaa gagttggatg tacatggttt atgatgagtt
   127561 gattggagaa atttattggg tgattggaaa gattcagtca gacccagaat tagaagaaca
   127621 attgcgacgg ttaaaatttg atattcgcaa gaatggtgtc aaagtcgctg gcgatccata
   127681 tttaatgaat gaggagacgg atgctcgaat tgaaataaat caagtaattg cagaatttga
   127741 gcggattgcg gaccaagcaa aagaaccaga tattcgtcaa tacttgttag aaatgaaagc
   127801 agagttggaa gtaaatggta ttacagatga gtaacctaaa ccaacacaac tgactgttag
   127861 gcgctgaccg cggaggattc gcgaagcaga aatcctccgt ggtgctgtgc ctgttcatgg
   127921 acggcgttag ccgaccatga tgtctcaccc ccgtatctaa caggggggta caaaaacaca
   127981 aaaaataagt aagcaaccat taagaatgct tgttgtatca aagatagtaa gtaatttgta
   128041 taggtgttaa ctcatttgaa aaagttaaca ccttgaattt ggaggtgaga acttggcaca
   128101 acggaattta gattatcggc tattaaaaga ccgacgcaac gaatacggcg tttcacaaaa
   128161 taaattggct acggcttgtg gacttagtcg gccgtactta aatcagatag aaaatggtgg
   128221 cgtaaccgca tctataaaaa ccatgaggaa aatttttgac caactggaaa gctttaatcc
   128281 cgatttgcct ttgacgttac tgtttgacta tgtaaggatt cgctttccca caacggatgc
   128341 acgaaaaatt attcaagaaa ttctccattt gaaatttgag tatatgctcc atgaagatta
   128401 tgccttttac tcctatcaag aacagtatgt catgggtgat attgtggtga tgttgtctca
   128461 tgaagaagat aaaggtgtgc ttttagaatt aaaggggcga ggttgccgac aatttgaaac
   128521 ttttttactc gctcaaaagc gtagctggta cgactttttc gaggattgtc taaaggccgg
   128581 tggcgtgatg aaacgcttgg acttggcaat caatgatcga gtggggctat tggatatacc
   128641 tgagctaacg aaaaaatgtc agaaggaaga atgtatctcc ttgtttcgta cctttaaaag
   128701 ttatcgttcc ggggaacttt taaaggctga tgaaaaggac ggcatgggca ataccttata
   128761 tatcggcagt ctcaagagtg aggtttattt ctgtttgtat gaaaaagact atgaacaata
   128821 tatcaagtta gggattccat tagaccaaac tgagacgaaa aatcgttttg agattcgact
   128881 gaaaaatgac cgtgcttttc atgcgattca agatttgtta aaaggtcgta gcattgagag
   128941 caccacgttt tccattatca atcgttactt gcgatttgcg gataaagtag aaggtaaaag
   129001 gcgaaccaac tggcccttga atgaacaatg ggggcgtttt attggacgga atcggaaaga
   129061 gattcaatta acttccgagc caaaaccgta taccattgaa cgaaccttga attggctagg
   129121 ccgacaagtc gcccctacgt ggaaaatggc taaggagttg gatcgattga atcggacaac
   129181 ctatatccag gatatggtac agaatgcacg cttatcagac cgacataaaa agattttgga
   129241 gcaacaaagt atggcaattg aaaatttgat tatatgaaaa gaggaatcgt catgggaatt
   129301 gtaaaagata tttttttggt atttggtggc agtatgcttg gtgttactgt gatgtgcttg
   129361 atgaatgcaa gtgcagcagc ggatcgagca atggaaaaga aaggaaagtg acaagatgaa
   129421 tttcggacaa aattt
//
LOCUS       DAPBCF010000002       114164 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.002, whole genome shotgun sequence.
ACCESSION   DAPBCF010000002 DAPBCF010000000
VERSION     DAPBCF010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 114164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 114164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..114164
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.002"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            173..445
                     /locus_tag="RD508_000121"
     CDS             173..445
                     /locus_tag="RD508_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734758.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
     gene            460..1383
                     /locus_tag="RD508_000122"
     CDS             460..1383
                     /locus_tag="RD508_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7734759.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(1523..2275)
                     /locus_tag="RD508_000123"
     CDS             complement(1523..2275)
                     /locus_tag="RD508_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7734760.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            2498..2860
                     /locus_tag="RD508_000124"
     CDS             2498..2860
                     /locus_tag="RD508_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HDT7734761.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            3497..4969
                     /locus_tag="RD508_000125"
     CDS             3497..4969
                     /locus_tag="RD508_000125"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDT7734762.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            4981..5805
                     /gene="nadE"
                     /locus_tag="RD508_000126"
     CDS             4981..5805
                     /gene="nadE"
                     /locus_tag="RD508_000126"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HDT7734763.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(5878..6768)
                     /locus_tag="RD508_000127"
     CDS             complement(5878..6768)
                     /locus_tag="RD508_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HDT7734764.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            6966..8483
                     /locus_tag="RD508_000128"
     CDS             6966..8483
                     /locus_tag="RD508_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HDT7734765.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            8455..9744
                     /locus_tag="RD508_000129"
     CDS             8455..9744
                     /locus_tag="RD508_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7734766.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            9919..10815
                     /locus_tag="RD508_000130"
     CDS             9919..10815
                     /locus_tag="RD508_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7734767.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            10829..11692
                     /locus_tag="RD508_000131"
     CDS             10829..11692
                     /locus_tag="RD508_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7734768.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            11698..12261
                     /locus_tag="RD508_000132"
     CDS             11698..12261
                     /locus_tag="RD508_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HDT7734769.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            12283..13794
                     /locus_tag="RD508_000133"
     CDS             12283..13794
                     /locus_tag="RD508_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HDT7734770.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            13806..14765
                     /locus_tag="RD508_000134"
     CDS             13806..14765
                     /locus_tag="RD508_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDT7734771.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            14851..15930
                     /locus_tag="RD508_000135"
     CDS             14851..15930
                     /locus_tag="RD508_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7734772.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(16182..17582)
                     /locus_tag="RD508_000136"
     CDS             complement(16182..17582)
                     /locus_tag="RD508_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HDT7734773.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            17800..19461
                     /locus_tag="RD508_000137"
     CDS             17800..19461
                     /locus_tag="RD508_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HDT7734774.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            19418..20116
                     /locus_tag="RD508_000138"
     CDS             19418..20116
                     /locus_tag="RD508_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDT7734775.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            20132..21556
                     /gene="araA"
                     /locus_tag="RD508_000139"
     CDS             20132..21556
                     /gene="araA"
                     /locus_tag="RD508_000139"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HDT7734776.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            21863..23022
                     /locus_tag="RD508_000140"
                     /pseudo
     CDS             21863..23022
                     /locus_tag="RD508_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            23140..24999
                     /locus_tag="RD508_000141"
     CDS             23140..24999
                     /locus_tag="RD508_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDT7734777.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            25109..25543
                     /locus_tag="RD508_000142"
     CDS             25109..25543
                     /locus_tag="RD508_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734778.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(25802..25963)
                     /locus_tag="RD508_000143"
     CDS             complement(25802..25963)
                     /locus_tag="RD508_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734779.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(25982..27004)
                     /locus_tag="RD508_000144"
     CDS             complement(25982..27004)
                     /locus_tag="RD508_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HDT7734780.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            27132..27485
                     /locus_tag="RD508_000145"
     CDS             27132..27485
                     /locus_tag="RD508_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDT7734781.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            27497..28663
                     /locus_tag="RD508_000146"
     CDS             27497..28663
                     /locus_tag="RD508_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7734782.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(28755..29375)
                     /locus_tag="RD508_000147"
     CDS             complement(28755..29375)
                     /locus_tag="RD508_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HDT7734783.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(29567..29863)
                     /locus_tag="RD508_000148"
     CDS             complement(29567..29863)
                     /locus_tag="RD508_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDT7734784.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            30067..30717
                     /locus_tag="RD508_000149"
     CDS             30067..30717
                     /locus_tag="RD508_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDT7734785.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            30733..32460
                     /locus_tag="RD508_000150"
     CDS             30733..32460
                     /locus_tag="RD508_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7734786.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            32457..34349
                     /locus_tag="RD508_000151"
     CDS             32457..34349
                     /locus_tag="RD508_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7734787.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            35053..35922
                     /locus_tag="RD508_000152"
     CDS             35053..35922
                     /locus_tag="RD508_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HDT7734788.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            36131..37156
                     /locus_tag="RD508_000153"
     CDS             36131..37156
                     /locus_tag="RD508_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HDT7734789.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            37195..38145
                     /gene="manA"
                     /locus_tag="RD508_000154"
     CDS             37195..38145
                     /gene="manA"
                     /locus_tag="RD508_000154"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HDT7734790.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            38239..39942
                     /locus_tag="RD508_000155"
     CDS             38239..39942
                     /locus_tag="RD508_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7734791.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            39944..41977
                     /locus_tag="RD508_000156"
     CDS             39944..41977
                     /locus_tag="RD508_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7734792.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            41988..42428
                     /locus_tag="RD508_000157"
     CDS             41988..42428
                     /locus_tag="RD508_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7734793.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(42628..43755)
                     /locus_tag="RD508_000158"
     CDS             complement(42628..43755)
                     /locus_tag="RD508_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7734794.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(43758..44435)
                     /locus_tag="RD508_000159"
     CDS             complement(43758..44435)
                     /locus_tag="RD508_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7734795.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            44699..46465
                     /locus_tag="RD508_000160"
     CDS             44699..46465
                     /locus_tag="RD508_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HDT7734796.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            46480..46917
                     /locus_tag="RD508_000161"
     CDS             46480..46917
                     /locus_tag="RD508_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7734797.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            46930..48081
                     /locus_tag="RD508_000162"
     CDS             46930..48081
                     /locus_tag="RD508_000162"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDT7734798.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(48143..48841)
                     /locus_tag="RD508_000163"
     CDS             complement(48143..48841)
                     /locus_tag="RD508_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HDT7734799.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(48834..50186)
                     /locus_tag="RD508_000164"
     CDS             complement(48834..50186)
                     /locus_tag="RD508_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HDT7734800.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(50409..51809)
                     /locus_tag="RD508_000165"
     CDS             complement(50409..51809)
                     /locus_tag="RD508_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HDT7734801.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            51970..52707
                     /locus_tag="RD508_000166"
     CDS             51970..52707
                     /locus_tag="RD508_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HDT7734802.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            52832..53311
                     /locus_tag="RD508_000167"
     CDS             52832..53311
                     /locus_tag="RD508_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HDT7734803.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            53308..54075
                     /locus_tag="RD508_000168"
     CDS             53308..54075
                     /locus_tag="RD508_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734804.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEELVVYSRSQRRRHS"
     gene            54305..54874
                     /gene="lepB"
                     /locus_tag="RD508_000169"
     CDS             54305..54874
                     /gene="lepB"
                     /locus_tag="RD508_000169"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDT7734805.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(54978..55580)
                     /locus_tag="RD508_000170"
     CDS             complement(54978..55580)
                     /locus_tag="RD508_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDT7734806.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            55686..56155
                     /locus_tag="RD508_000171"
                     /pseudo
     CDS             55686..56155
                     /locus_tag="RD508_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            56261..56845
                     /locus_tag="RD508_000172"
     CDS             56261..56845
                     /locus_tag="RD508_000172"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HDT7734807.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            56848..57921
                     /gene="prfA"
                     /locus_tag="RD508_000173"
     CDS             56848..57921
                     /gene="prfA"
                     /locus_tag="RD508_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDT7734808.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            57914..58753
                     /gene="prmC"
                     /locus_tag="RD508_000174"
     CDS             57914..58753
                     /gene="prmC"
                     /locus_tag="RD508_000174"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDT7734809.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            58746..58925
                     /locus_tag="RD508_000175"
     CDS             58746..58925
                     /locus_tag="RD508_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734810.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            58947..59972
                     /locus_tag="RD508_000176"
     CDS             58947..59972
                     /locus_tag="RD508_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDT7734811.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            60147..61391
                     /locus_tag="RD508_000177"
     CDS             60147..61391
                     /locus_tag="RD508_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDT7734812.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            61544..62491
                     /locus_tag="RD508_000178"
     CDS             61544..62491
                     /locus_tag="RD508_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7734813.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            62625..63254
                     /gene="upp"
                     /locus_tag="RD508_000179"
     CDS             62625..63254
                     /gene="upp"
                     /locus_tag="RD508_000179"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDT7734814.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(63393..63635)
                     /locus_tag="RD508_000180"
     CDS             complement(63393..63635)
                     /locus_tag="RD508_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734815.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            63756..63828
                     /locus_tag="RD508_000181"
     tRNA            63756..63828
                     /locus_tag="RD508_000181"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:63789..63791,aa:Thr,seq:cgt)
     gene            complement(63947..64585)
                     /locus_tag="RD508_000182"
     CDS             complement(63947..64585)
                     /locus_tag="RD508_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDT7734816.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(64708..65340)
                     /locus_tag="RD508_000183"
     CDS             complement(64708..65340)
                     /locus_tag="RD508_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDT7734817.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            65691..65990
                     /locus_tag="RD508_000184"
     CDS             65691..65990
                     /locus_tag="RD508_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDT7734818.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            66485..68650
                     /gene="acm"
                     /locus_tag="RD508_000185"
     CDS             66485..68650
                     /gene="acm"
                     /locus_tag="RD508_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HDT7734819.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(68922..69407)
                     /locus_tag="RD508_000186"
     CDS             complement(68922..69407)
                     /locus_tag="RD508_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDT7734820.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    69497..69842
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            69887..70528
                     /locus_tag="RD508_000187"
     CDS             69887..70528
                     /locus_tag="RD508_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7734821.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            70547..71182
                     /locus_tag="RD508_000188"
     CDS             70547..71182
                     /locus_tag="RD508_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7734822.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            71200..72015
                     /locus_tag="RD508_000189"
     CDS             71200..72015
                     /locus_tag="RD508_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7734823.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            72334..73770
                     /locus_tag="RD508_000190"
     CDS             72334..73770
                     /locus_tag="RD508_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7734824.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            73959..76406
                     /locus_tag="RD508_000191"
     CDS             73959..76406
                     /locus_tag="RD508_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDT7734825.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            76636..77703
                     /gene="rlmN"
                     /locus_tag="RD508_000192"
     CDS             76636..77703
                     /gene="rlmN"
                     /locus_tag="RD508_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDT7734826.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(77896..78999)
                     /locus_tag="RD508_000193"
     CDS             complement(77896..78999)
                     /locus_tag="RD508_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7734827.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            79552..80100
                     /gene="aac(6')"
                     /locus_tag="RD508_000194"
     CDS             79552..80100
                     /gene="aac(6')"
                     /locus_tag="RD508_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HDT7734828.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            80646..82307
                     /locus_tag="RD508_000195"
     CDS             80646..82307
                     /locus_tag="RD508_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7734829.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(82377..82724)
                     /locus_tag="RD508_000196"
     CDS             complement(82377..82724)
                     /locus_tag="RD508_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HDT7734830.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            82808..83749
                     /locus_tag="RD508_000197"
     CDS             82808..83749
                     /locus_tag="RD508_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7734831.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            83750..84793
                     /locus_tag="RD508_000198"
     CDS             83750..84793
                     /locus_tag="RD508_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7734832.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            84799..85869
                     /locus_tag="RD508_000199"
     CDS             84799..85869
                     /locus_tag="RD508_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7734833.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            85859..86812
                     /locus_tag="RD508_000200"
     CDS             85859..86812
                     /locus_tag="RD508_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7734834.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            86824..87834
                     /locus_tag="RD508_000201"
     CDS             86824..87834
                     /locus_tag="RD508_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7734835.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(88119..88940)
                     /locus_tag="RD508_000202"
     CDS             complement(88119..88940)
                     /locus_tag="RD508_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDT7734836.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(89037..89315)
                     /locus_tag="RD508_000203"
     CDS             complement(89037..89315)
                     /locus_tag="RD508_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734837.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            89583..91592
                     /gene="metG"
                     /locus_tag="RD508_000204"
     CDS             89583..91592
                     /gene="metG"
                     /locus_tag="RD508_000204"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDT7734838.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(92071..92658)
                     /locus_tag="RD508_000205"
     CDS             complement(92071..92658)
                     /locus_tag="RD508_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734839.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            92833..94155
                     /locus_tag="RD508_000206"
     CDS             92833..94155
                     /locus_tag="RD508_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7734840.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            94310..95086
                     /locus_tag="RD508_000207"
     CDS             94310..95086
                     /locus_tag="RD508_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDT7734841.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            95079..95648
                     /gene="rnmV"
                     /locus_tag="RD508_000208"
     CDS             95079..95648
                     /gene="rnmV"
                     /locus_tag="RD508_000208"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HDT7734842.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            95641..96525
                     /gene="rsmA"
                     /locus_tag="RD508_000209"
     CDS             95641..96525
                     /gene="rsmA"
                     /locus_tag="RD508_000209"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDT7734843.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            96976..97605
                     /locus_tag="RD508_000210"
     CDS             96976..97605
                     /locus_tag="RD508_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734844.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(97729..98838)
                     /gene="ugpC"
                     /locus_tag="RD508_000211"
     CDS             complement(97729..98838)
                     /gene="ugpC"
                     /locus_tag="RD508_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HDT7734845.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            99047..99469
                     /gene="mgsA"
                     /locus_tag="RD508_000212"
     CDS             99047..99469
                     /gene="mgsA"
                     /locus_tag="RD508_000212"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDT7734846.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            99792..100328
                     /locus_tag="RD508_000213"
     CDS             99792..100328
                     /locus_tag="RD508_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HDT7734847.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(100368..102131)
                     /locus_tag="RD508_000214"
     CDS             complement(100368..102131)
                     /locus_tag="RD508_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7734848.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(102134..103849)
                     /locus_tag="RD508_000215"
     CDS             complement(102134..103849)
                     /locus_tag="RD508_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7734849.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(104628..104852)
                     /locus_tag="RD508_000216"
     CDS             complement(104628..104852)
                     /locus_tag="RD508_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734850.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            105043..107820
                     /locus_tag="RD508_000217"
     CDS             105043..107820
                     /locus_tag="RD508_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7734851.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            107901..108320
                     /locus_tag="RD508_000218"
     CDS             107901..108320
                     /locus_tag="RD508_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HDT7734852.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            108332..108802
                     /locus_tag="RD508_000219"
     CDS             108332..108802
                     /locus_tag="RD508_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7734853.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            108819..109598
                     /locus_tag="RD508_000220"
     CDS             108819..109598
                     /locus_tag="RD508_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7734854.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            109585..110406
                     /locus_tag="RD508_000221"
     CDS             109585..110406
                     /locus_tag="RD508_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7734855.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            110423..111472
                     /locus_tag="RD508_000222"
     CDS             110423..111472
                     /locus_tag="RD508_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7734856.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            111485..112489
                     /locus_tag="RD508_000223"
     CDS             111485..112489
                     /locus_tag="RD508_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7734857.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            113122..114141
                     /locus_tag="RD508_000224"
     CDS             113122..114141
                     /locus_tag="RD508_000224"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDT7734858.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT        37901 a        19802 c        23440 g        33021 t
ORIGIN      
        1 cattcactaa taataaagat atatttacag tatcattata atgtattcaa tttaaaataa
       61 gagactttgg taataatgaa agaggaataa aacttttctt tggcaaaaca aactccttgc
      121 tatgagacgc gtttcataca ctatactcaa agtatcaaaa ggagggcttg caatgaatac
      181 ttatgtagag ataacagatg gcacaacgaa caattatttt tatgcgtttg tcgagttcaa
      241 gggatccgta ttaacgttgt acagttttca agggttgaat aggaatatag taaaagaaat
      301 accaatgaat gaaatcgaaa atttgacaaa agatatatat tggggcgggc agcggatcag
      361 tttttcgcat gaaggaaaaa tgtatcagtt ttttgaatgc ggtccagctg tggtagacta
      421 tttacaagaa aatctttttg tataggtggc gaagcagcag tggcaaacat tcgagatatc
      481 gcaaagctca caggttattc agtttctact atttcacgtg taatcaatgg acatccatat
      541 gtagatgagg aaaaaaggaa agaaatactt gcggtcatga aagaagtcga ttatatccct
      601 aatgcaaatg ccagacagtt aagttatgga aaaacgaaaa gcattggagt gattctgcct
      661 tataccaatc atccgtattt tgatcagttg atcagtggga tcattgaagc agcgtttgat
      721 tatgattaca aagtgacact tttaccgacg ggctatcata aagaaaaaga gcgaaggtat
      781 cttgaagaat ttgcagctaa agctttcgat ggattgatca ttacgtctcg tgccaataca
      841 ctagatgatt tattggcata tcaaaaatat ggacctctag ttttttgtga agaaatcaag
      901 ggaaaacagg caagctgtgt ctttattgat cgagaacaat caattacaga aggtcttact
      961 tatttgaagc agcaaggtat aaagcaattg ggcatcacgt tggggcgaag tggcaggcta
     1021 agttataact caaaaatcac tttgcagcta tgtcatcaac tttttccatc ttttgatgaa
     1081 tcacttgttt tttgggattg tatagatgca gagaaaggaa aacaagcagg cttctttttt
     1141 aaagagcttg gagttgatgg tgtctttaca aattcggata tggttgcagc aggcatcttg
     1201 caaagctatc tgcaagataa gacaccagtg gtgattggac gcgataattt gctgatcagc
     1261 gagcttcttg gtttcccaac catcgaccac catctggaag cttgcggaga aatggcattt
     1321 caattgtttc ttacagaaaa aaaggataaa gtgaaaatac cttatacgtt tattcaacga
     1381 tgaatatatt taaagtagga tgaaaaaact tgtgaaagaa tggagcagac accaaaagtt
     1441 agcataaaaa tctaacttgg gtgtctgctg ttttgttatt aggtcatttt acgtgtactt
     1501 ttttgttgga tcatgtaaaa gattacgcct ttttttggat aatttcattt aaagcttttg
     1561 ctgcaccatg accacttcgc tcgtcataat atgcagtgaa ccgttcatcg gcttcgtaca
     1621 tcattcctag tcctttatgc gcttttggct gatattcagg ccagctgtaa gagaaccact
     1681 tcttatgagc ttggaagata cggtctgcta agctttcatc ttctggttct tttaagtaaa
     1741 gagtgagatc aaataacatc tgcttttcaa cagtttgcat ttcttcatac gtttctttat
     1801 ccatattcat ccatttttca ttggatgctg taaccttttt ttttccgtat ttttgtcgaa
     1861 tctcttgtcc ataggattct tcattttctt tcaacttttg ttgtttaaac ccttcaaatt
     1921 tttctttgtc actcattttt cttcctcctt cgtacatatc aagtgtctgt tggacagttg
     1981 tcaagagggt atcgatttgt gcccgttttt ccagcaacat ttgctgatgc ttgattaaag
     2041 ctttctggtg gtcaaaagat ggattgtcta agacctcttg gatatcatcc aacttgaatg
     2101 ccattgttcg ataaaataag atgtgttgca gacgatcgac ttcttttttg ccataaatcc
     2161 gataacctga agaattgatc ctagctggtt ttagcagtcc aatctcatca taaaagcgca
     2221 aggttctcgg actgactcct gatatctctg acattttctt tattgtgtac tccattattt
     2281 ttcctcctga caaatgtaag cataatcctt tacgtaacga gatggtcaag aaaaaattgt
     2341 atttttttct cacgaaatta tgttatacta ttaagtgata aaaggtaaat ccttttgtct
     2401 ttaaaggttc aattgtaacc gattccttaa tgctaggaaa gatggtaaca taacttaaga
     2461 ttggatctaa atcgactata tagaaaagag gaatgagatg aagctaatcg aaacacctgt
     2521 gaatagtaat ttaaatatta agacatttta tcctaaagta gtggaattct tttttgggaa
     2581 tacggctatt aattattaca aattattttc gttagatcga acacaactgc tattggtaga
     2641 cacatatgat aaaaagcaag tcgtgatgat caatacgaag aaaaaaatca caaggcaaga
     2701 aatcgactat gcgattcatc acgttttaaa aatgacacga gaagatgtca aagtccatgt
     2761 aggagtgaaa caggagctag aacgtgccgg aatacaattc aaacgtccaa ataaagatat
     2821 tgtagtgata gaacaaaaaa atacgaagga ttctatttaa taacgactaa taatcatctt
     2881 tatggtaacc tgctccatat ctaatgtata caataaaaaa caaggcgaga ctgattgatg
     2941 tctcgccatt tttgtttcca ttctattgac agctgctttc ttactttgta tctttttaaa
     3001 aacgtgtgat attttttccg cgagtttttt caacgcaagg tatatcttgt cataattcgc
     3061 ctttccaaaa aaattcaata cataataagt tatatccgtt tctttgggga taagaagcaa
     3121 aaaaggaaag acgtattatt gcttcaaaaa cttttgccat tgattatgtt gtagagacat
     3181 ttggttatat ttgttcaatc atcggtatct taacggctac gattgtagta ggaaaatcta
     3241 cttattttat caagtaagaa aaatagaaaa cgctaatttc ttcgtgtctc ggatacattg
     3301 aataaaataa gtattctttc tcgtttaggt taaataccaa taagaaagga tagttttagc
     3361 agatggagtt catttttagc aagaaatatc cgtaaaacat gtgctttttc agaaaaaatg
     3421 gaagatttct tttcctatta attttttttg ttataatggg taggaaatga aaacttgcca
     3481 agaggagtaa tacaagatga ataatactta cccagacgac agtttgacgc tgcatacgga
     3541 tctatatcaa atcaatatga tgcagacata ctgggaatta ggtcgagctg atttacatgc
     3601 tgtttttgaa tgttactttc gagaaatgcc ttttaaccac ggatacgcgg tttttgcagg
     3661 attggaacgg ttagtcaatt atttagagaa tctgacgttc aatgattccg atattgctta
     3721 cttgcgtgga ttagaagtct atcctgaagg ttttttggag tatttacaaa attttgaatt
     3781 taaagcaaca gttcgttctg ctcgtgaagg agaactagtt tttgcaaatg aaccattaat
     3841 ccaagtggaa gggcctttag cgcactgcca attagtagaa acagcactgt tgaatatggt
     3901 caatttccaa acgttgatcg cgacaaaagc agctcgtatc aaatctgtca tcggagaaga
     3961 tccactattg gaatttggaa ctagacgggc acaagaactg gatgcagcag tctggggaac
     4021 tagagcggca tatatcggcg gagcagatgc aacaagcaat gtacgtgctg ggaagatatt
     4081 tgggatacca gctagcggga cccatgctca ttcgttagtc caatcttatg gaaatgatta
     4141 tgaagcattt atggcctacg ctaaaaccca taaagactgc gtgttcttag tcgacactta
     4201 tgatacgttg aaatcaggtg tgccaagtgc gattcgcgtg gcgaaagaat taggtgacaa
     4261 aatcaacttc caaggcgtac gcatcgacag tggagatatg gcctatatat ctaagcgtgt
     4321 tcgggaacaa ttagatgcag ccggatttac ggaagcaaaa atctatgctt cgaatgactt
     4381 ggatgaagca acgattttga atttaaagat gcaaaaagct aaaattgatg tatggggtgt
     4441 tgggacaaaa ttgatcacag cctatgatca gccagccctt ggtgcagtat tcaagctagt
     4501 atcgatcgaa gatgatgaag gaaaaatgat ggatacgatc aagttatcaa gcaatgcaga
     4561 aaaagtaact actccaggga aaaaacaagt gtggcgcatc actcgaaatt ttgatgggaa
     4621 atctgaagga gactacgtga cattatggga tgaagaccct cgagaagaag aagctatctt
     4681 catgttccat ccagtgcata cgtttatcaa taaaactgtt cgagacttta cagctcgccc
     4741 agttttacaa gatatcttta tcgaaggaaa aagagtttac gaattacctg cactaaacga
     4801 aatcaaagaa tatacaaaag aaaatctaga ttcactatgg gaagagtata aacgagactt
     4861 gaatccgcaa aaatacccag tcgatctgtc tactgaatgc tggaaccata aaatggctat
     4921 catggaacga atgaaaaaaa gcgtagcaga acttcataca gaagcatagg aggagaataa
     4981 atgagcctgc agacagaaat tatcaatgaa ttaggtgtca aaccaacaat tgatccaaaa
     5041 gaagaaatac gtaaaagtat tgactttatg aaagcatatt tgaaaaaata tccgtttctt
     5101 aaaacttttg tactaggtat cagcggcggc caagattcta ctttagcagg ccgtttggcg
     5161 caactaacga tggaagaaat gcgtgaagaa acaaaagatg aaaactatca atttatcgct
     5221 gttcgtcttc cttatggtga acaagcagat gaagaagatg caaaagctgc tcttgacttt
     5281 atccagcccg atgttagtct gcgagtaaat atcaaaccag ctgttgatgc acaagtacaa
     5341 gtattaagcg aagcaggtgt gggaatcagc gattttaaca aaggaaatat caaagcacgt
     5401 caacgtatga ttacgcaata tgccgtagct ggagaaagag caggagccgt attagggaca
     5461 gatcatgctg cagaaaacat tactggattc ttcacgaaat ttggtgatgg tggagccgac
     5521 attttgccat tattccgttt ggacaaacga caagggaaac aattgcttca agcattgaat
     5581 gcaccggaaa aattatacac aaaaattccg actgcagatc ttgaagatgg gaaaccaatg
     5641 attgcagatg aagtcgcact aggtgtcaca tataatgaaa ttgatgatta tctagaagga
     5701 aaagaagttc ccgctcaagc acaagaaaaa atcgaagcat ggtggaacaa gacacaacat
     5761 aaacgacatt tgccaatttc cgttttggat gatttctgga aataacaata aagcaaaaac
     5821 agccgtccct tcatagggat tggctgtttt tgttttataa aatagaaaag aaaaatatca
     5881 gctgtagtaa acttttaatt tgatatcctg atcgtaatta ccgaatcctt taccaaataa
     5941 agtacagccc cccacatgtt tggcatcgtc tttcacttcg attcgcaaat gccaagtgtc
     6001 ttgctcttta gggatgtcgt tgatcgtgat gtttgacaag ggttctccat tcatattcgt
     6061 caagtgtttg gtaattcgga tcgtcttcag caagccgtat tgattaagat tatctggata
     6121 ccaatcaggc gtatatttac cgcggatatc agcaaaatct ccagggctcg tccatgttcc
     6181 tagctccaca ccatttaggc tgaaagtgat atctgaaggc caattgtcat ttgaaaaagg
     6241 aaattcagaa gaaatttcca cagaaacttc caacatctcc aatgtatcct ctgtatttaa
     6301 aaaattaggt gcctgatact cgacaaatcc gctggtaaac cagagaatgc gggcatccat
     6361 ccttcgagga tccataaaat agcgtggttc atccactttc ccgataaaat catggatcgt
     6421 agctaaaccg catgttggtt caattgcata atttgtatag tgaccaatag gtatcgatgt
     6481 ttctttcgta tcaaaagcat tgaatatttt ttctggaaaa ctgatatcga ttttatcgac
     6541 acgaaggctc gaaatttttt gttgtcctac tttttctgtt ttgatgatgt ttgcttcctc
     6601 tagctttttc acgtgcatcg tcgtgatagc actgctcact ccaagttctt ttgccaaatc
     6661 tttgacattc atcttttttt tggaaagtag ctggatgatc ttgatccttg ttttactagc
     6721 taatgcttca tataccggta aggattcttc gtttatttgt agttgcatat atatcacctc
     6781 ttaaaaggtt tttcttatat attaacatat ttgttaataa aagttatatt aaattatttg
     6841 ttttaatcat tattaatatt ttggttaatt aaaatcgata aaaaataagt aagtttaaca
     6901 tttatattat tgacaacgct ttcaacgagg tgtattattc atgtataaat taaaggaggt
     6961 cagttatgga agccacaatg ttgattagta gtgtcaagcg tgtaggcaaa gttgatccgc
     7021 ggttgtacag ttcatttatt gaacatatgg gacgagcagt atatgaaggg atttatcagc
     7081 cagatcatcc atcagctaat aaaagtggat ttcgccaaga cgtcattcac ttggtaaaag
     7141 aattgaacat tcccatgatt agatatcctg gtggaaattt tgtgtcagga tttcgttggg
     7201 aagacagtat tgggcccata gcaaatagac ctagaaggtt ggatttagct tggcggacaa
     7261 ttgaaacgaa tgaagttggg attcatgaat tttataactg gtgtcagcat gtgggggccg
     7321 aaatcaatat ggctgtcaat ctgggtactc gtggagtaga tgcagctcgt aatttagtcg
     7381 aatattgtaa ttttcctaaa ggaacttatt ggagtgattt aaggcgttcg aatggtcaag
     7441 agagcccttt tggaattaag acatggtgtt tagggaatga aatggacggt ccttggcaga
     7501 ttggacataa aacagcggaa gaatatggac ggttagcaga ggaaacggct aaggcgatga
     7561 aactcgtaga tgattcaatt gaggtggttt tatgcggaag ttcgaatcgg caaatgccta
     7621 catttggtga ttgggagtta acagttcttg atcaagcgta cgatcaaata gattatttgt
     7681 ctctgcatca atattatggc aaccaaaaaa atgatctttc tcattatctt gcacgttcct
     7741 tagacatgga tcggttcatt tctgaagtga cagcgatgtg cgatacagtc aaggcgaaga
     7801 aacatagtaa gaagcagatc aacctgtcct ttgatgaatg gaatatttgg tatcattcag
     7861 cggaacaaga tgagcaagca gcgccttggc agattgctcc tcctttacta gaagataact
     7921 ataattttga agatgcatta ctattaggct gtctattaat cactttattg aaacatgcag
     7981 atagagtaaa gattgcttgt cttgctcaat tggtaaatgt tattgcacca atcaggacag
     8041 aaacaaacgg agaagcttgg agacagacga tctattatcc atttatgcaa gctgctgtgt
     8101 atggacaagg agaggtgtta agcccacaaa ttcgttcagc aaactatgcg acggaagatt
     8161 ttgaagaagt gccgtattta gaaagtatag ccgtaataaa tgacaaagaa cttgtcatat
     8221 ttgcagttaa ccgtggagaa gaagaaatga atctaactgt tcacttgtct gaattatcat
     8281 tagagggagt gattgatttt tctgaaatga gtggatttga tacaaaagca actaatcttc
     8341 ctaaaagtga acaagtaaaa ccaagtcatt caacaaatgt aaaagctgaa gatgggaaaa
     8401 tcaattgttt attgaaaccg ctatcttgga atgtggtcag atgtcgttta tcagatgaag
     8461 gaggaacaaa aaatgaaagg taaaaaatgg ttaattggct ctttgttggt agctgcaaca
     8521 ggtattttag gagcttgcgg tggcggaagt tcagcagaat ctgattctga taaagaagtg
     8581 actttgactt tttggaatgg gtttactgca tctgatggtg aaatattgca agaaatcgtt
     8641 aatgaattta ataaaacaaa tgataaaaac atcaaaattg aaatggatat catgacttgg
     8701 gccaatttga atgaaaaact tcctacagcg atttcttcta aaaaagcacc tgactttatt
     8761 gcattaaatt atccagattt tgcacagtat gtagaaaacg gagcggtaca accattagac
     8821 gatttctggg aatatgatgg agtagataaa tctgatttta aagaaacggc tattgaatta
     8881 ggtgaagtag aaggtaaaca gtattttgtc cccatgcagg tacaaggcat gtatatgtat
     8941 tggaataatg atttgtttaa acaagctgga ttagatactg aacaaccacc tactacttgg
     9001 gaagaattga cagaaatggc accaaaatta actgatagta gtaaaaatgt atcaggtttt
     9061 gtcttcaata aggatggaac tgcaccgtta tataactgga tgttagcaaa tggcggtaaa
     9121 ttagtgaacg atgattatac taagtctgaa tttgcgtctc ctgagaacct taaaacgtta
     9181 aaagcgatcc aaaaaatgat ccatgtagac aagactggtc cagaatcgat ttctggcgcc
     9241 gaaatggaca atttaatgaa tgctggtcaa ctagccattg aaatcaatgg gccatggtta
     9301 aataacggat tgaaagcaaa cgagattgat tataatgtga ctaccttacc acaagggagt
     9361 gattcagaca aaaaaacagc tattttagat ggcgtaggat atgccattcc ggcaagtaca
     9421 gataataata aaaaagaagc tgtctatgag tttttgaaat attggaatac aactgaaatt
     9481 ggtaaaaaat ggagtatcga aaatggtttt cctgcctact tggattcagt agcaaaagat
     9541 gaagaagtaa aaaatgatcc tattgtatct gaattatcga aacaaatgga ctatgcagag
     9601 ccatatttac caggttttac ccaaatctct gcgatcaata acgatatcat caatccactg
     9661 attgaaaaat tattagcagg agaagatcct gagacactca tgaacgatgc agatgatgcc
     9721 atcaatcaat tactgcaaaa atagtacaga actttataca ggatagactg ttggcaagat
     9781 acagatatct gaatgatcga cctagtattt gcagataggt gttattgcaa aaatcacagc
     9841 gattgttcgg atatcttatt cagattcgtt taaaccaaga ttgtatattt tatcaaaatg
     9901 aaagatgagg tggactatat gaacggattc accaaatatt ggaatcgtcc tgatcgtgct
     9961 gcgtatttgt ttttaactcc atctttttta gttttattat tatttactgt cataccgctt
    10021 ttaggaacat ttgctattag ttttacagat ttgaatattt tctttacatc aagaaatttt
    10081 gtaagttttg aaaatttcac acgtatattt agtgatgaac gagcagttaa ttcgttgatt
    10141 cattctttat atttcaccgt actcgaaacg ccaacacaaa ttatcgttgg tttattagca
    10201 gcagtagcat tatctaaaaa taccagattc aatcgttttt gtcgttcgac attttacatt
    10261 ccagttattt gttcattgac gtcaattgcg attatttttt ctatgttgct tgatccgaat
    10321 gtaggggcga ttccttactt gttttcacaa gtcggcttgc cgatccctca attttttcgc
    10381 gatccaaccc ttgctatgcc gacggtagcc atcatgactg tttggaagaa ttttggtgtt
    10441 actatgacga ttctcttgac tgctattcag ggaatctctc cctctttgta tgaatctgct
    10501 caaatggatg gtgcaacaaa tcgacagcag ttttttaaca ttacgctacc tcagatcgtt
    10561 ccctccttag gtttttgtat tttaacgaat ctgattggtt cgatgcaagt gtttgaccaa
    10621 gtatatgttg caaccgctgg tggcccacaa tttaagacag aaacagctgt tcaatatatt
    10681 tacagtcgag gatttacagc accttatgaa ttgggctatg catcagcact gtcttcggtt
    10741 ttgtttatca ttgttgcaac tatagctatc tccactaatg tgtacatgtc acggaaagaa
    10801 aaacaaatga aataggaggg aaacctgtat ggcaccagaa agctcgatta cagttactgt
    10861 gaatagtcga aaagcagtta gtggtaaaaa aatcattcga acgattagta tgctagttat
    10921 attgttggtt attgcgtttc cttttttgtg gctgattatt tcttctttta aacacgaaaa
    10981 agacattatc tcatttccgc ctagaatatt tgcagatagc tataccctag ataactatat
    11041 taaggtttgg acaacgatcc ctttattaga ttacatcaaa aatacagtga tttttgctgg
    11101 agggacagtg atcacttctg tattctttga ttctcttgcg gggtatgcat ttgctcgtat
    11161 gcgtttcaaa ggaaaatcag ttttgttcta tttcgttttg ctgacaatga tgatcccatt
    11221 ccaagtcttc atgattcctc tatttattga agtcaatttg cttggcatgc ttgatactta
    11281 tgcaggtttg atcattcctc gtatgacaac tgcatttggt atcttcatga tgcgttcctt
    11341 ttttattact ttaccagatt ctttggaaga ggcagcacgc attgatggat taagtgagtt
    11401 taatattttt ttgaaaatca tgttgccatt gagcaaacct actcttttat cattagggat
    11461 tttcacgctg atgaatagtt ggaatgactt gctttatcca ttgatattga caagtagttc
    11521 aaaaatgaga actttaccag cagggttagc tttatttaca gggcagaaca tttcttttta
    11581 tggacctgta atggctggaa cggttatttc aatgctgcca ttactagtgg tttatatttt
    11641 tgcacagaaa tattttgttc aaggaacagc tatgtctgga atgaaagagt gaggaagatg
    11701 aaaatagttg agactaaact ttatggacag ttgattgtgg tttctgatta catcttatta
    11761 ggtattctct gggtaatcgt gtgtttgcct gttattacta tcgtgcctgc tacatgtgct
    11821 gttttttatg taatggcgca atggaaaggt gagggatcag gaaatatcat ttattttttc
    11881 tttcaaggaa taaagcaaca ttttggtaag aacttgttcc ttagtctgtt aacgatcatt
    11941 atttattttc ttgttaatca attattagaa gaacagacaa tcgtactttc aattagtgga
    12001 tatgtagttt tacttattta ttccatgttt cttttatcct ggatatatgt gatttctgaa
    12061 aacaaagata tcacattttt acaaattttt gaacaaagtg catggaaagt attttttgat
    12121 tttttgagaa atattctttg ttgcgtattg ttattaggat ttgtactgct catatttctt
    12181 ttccctcctt ttatttttat ctttgctggt ggcgtatgga aacttgtatc tattatcttg
    12241 actataggaa atgaaaggta gggaaagctg ttggacgaag aagtgaaagt aaaaatcaga
    12301 gaggatttta cggtaggaga gatcagttct cggctgtttg gctcatttgt tgagcatatg
    12361 ggaagtgtcg tctatacagg gatttatgaa ccgggccatg aaacagctga tggtgacggg
    12421 tttagacaag atgtcctctc ttatgtaaag gaattagaat taggtgtcat tcgctatcct
    12481 ggaggaaact ttacatctgg ttatgattgg gtggatactg taggtaggaa agaacaacga
    12541 ccaaaaaaaa ttgatttagc atggcgaggt atagaaccaa attcttttgg actccacgaa
    12601 ttttttaaat ggatcagtca tgtacaagcg aaaccgatat tcacggtgaa tttaggaaca
    12661 aaaggaattg atgaagcaaa aaatttagta gaatattgta attttccaaa aggaaccttc
    12721 tggagtgatt taagaataaa aaatgggcaa aaaaagcctt ttggcgttaa attatggtgt
    12781 ttagggaatg agctagacgg tccatggcaa gtgggggcta agagtgctta tgaatatggt
    12841 aggttagcaa atgaagcctc aaaagtcatg aagttagtgg atgattcaat tgaaacaatc
    12901 ttagttggaa gctctacgcc acgtttacca tcgtaccctg aatgggatcg tatcgcatta
    12961 gaagaagctt atgagaatgt agattattta gctttgcata actatattga taagtatgat
    13021 gaagaagact tgactaaacc tcctaaaaat gagcgtgatg atacagcgac ataccttgca
    13081 aaagcttatc gattcgatcg tcaaattgaa gaaatcgttg ctacttgtga ttatgtaaaa
    13141 ggatatttga gaagtgagaa aacaatgtat ctagcgtttg atgaatggaa tgtacatgcc
    13201 caaccggaaa aaagacatag ggattttgaa gtcggtagtc ccatcgattg gtgttacttt
    13261 actatggaag atacattatt atttggttca ttagggctgg ctattttacg acacgcagat
    13321 cgcgtaaaga ttagttgtca atcattgtta gtaaacacaa tacctttaat actgacagat
    13381 gctaaaggac aagcatggag gaatccaact tattatgtga tgcaacactt atcgaaatat
    13441 gctaaaggtc aagtattgaa acaacaaatc atttgccctg tttatgattg tgaaaagata
    13501 aaaaatgttc cttatgtgga cagtgtgatc gtagataacg gcaatcagct gactattttc
    13561 ttgatcaatc gcacaaatga acaacaaaag ataacgattg aacatgattt caatttgcta
    13621 gatcaaggag agcactacac attaaccagt agcgatctgt tggacaaaaa tacacgtgaa
    13681 gaaccagaaa aaataaaacc tgaaataaac tatttttcaa tagaaaaaca tgacgaatta
    13741 aatgtaggga tagaaaaata ctcttggaat gtaattagaa taaagaaaat gtgaggaaat
    13801 ttgttatgat gaagacactt tataataatc ctatcgttcg gcaacgggca gatccttggg
    13861 tatataaaca tacagatggt tattattatt ttacaggatc ggttccaggc taccaagtga
    13921 ttgaattaag aagggcaaag tcactgaatg aattagaaca tgctgcaagc ctgattgtat
    13981 ggcaggctca tgaagaagga ccgatgagtg aattgatctg ggcacctgaa gtccattata
    14041 tcaatggaaa atggtatatt tactttgctg caagcaatca taaaactata cgtgatgaat
    14101 ctcatcatca ccgcatgttc gtacttgaaa atcagcatat agatccaatg aatacagatt
    14161 ggatagaaaa gggacaaata aaaacgaaaa gggaaacttt cagtttagac ggaacaactt
    14221 tctcttctca aggaaagcta tattatgtgt gggcccaaca agatcctgaa attactggga
    14281 attctaatct ttatctatcc gaaatggata atccttggac gttaaagggg aagcagatcc
    14341 tcctttctat acctgagtat gaatgggaaa aacggggttt ttcagtaaat gaaggtccag
    14401 cagtccttac tcgcaatggg aaaatattca ttacgtattc tggtagtgca acagatgaaa
    14461 actatgccat gggcctgctg tgggctgatg agcacaagaa tcttttatta aaagaatcat
    14521 ggcataaatt atcggagcca gtattcgttt cttctgaaaa aaataagcaa tttggtcctg
    14581 gtcacaactc gtttacggtt tcagaagacg ggtgctttga tattttgatc tatcatgctc
    14641 gaccagagaa gaaccaaaaa ggggatccgt tagacaatcc taatcggcac gcgaacgcgc
    14701 aatgctttac gtggaatgag caaggatttc cagaatttgg tgaacctgtt ccgtatgcct
    14761 tatgagcaca agaaaccttg atttttgctt gaataaacct tgcagactcg ttatgatata
    14821 tgtacgtaca aataaaaagg ggcaaggcaa atggcaaaat atcaagatat tgcagaagag
    14881 ataaaacaaa agatccttcg tgaggaatac gaagtaaata caaccattcc ctcagaattc
    14941 aagctgcaag aaatatatga cgtcagcaga catacgattc ggcaagcaat cgctgtgttg
    15001 gtaaatgagg gctatctgcg taaagaaaaa gggtcgggca catatgtaga tgacagctat
    15061 aagaaagaaa aaacaccatt gaacagaaca aaaacgatcg gtgtcatcac cacatatctc
    15121 tctgattata tttttccgtc gattatccga ggaatcgaaa atgaattacg agaatctggg
    15181 tattcattgc ttttagccag tacgaataac gatcacgaat tggagaaaga gtgtttgaag
    15241 aaaatgattg cttatggggt agatggtttg atcgttgagc ctacgaaaag taatcagtat
    15301 aacccaaact tagcacttta tgttgctttg agagaacaag gcattccgat ggtgatgatc
    15361 aatgctgctt atgaagagtt aaatgcctct tatatttgtt tagatgatgt gaaagtcggt
    15421 tttatggcag cagaatattt gataaaaaaa ggacatcagc gtctgttgtt catcacaaaa
    15481 atcgacgatc ttcaaggaaa atacaggatg aaaggtttta tcagcgcgtg tgaacagtat
    15541 aatgtgcgtt ttttgacgga agatatcatt actttcacca cggaaacacg agaaacaatc
    15601 gctgaaaaaa cagtacaacg gttgaaagaa gaacaagctt tagatggcat catttgctat
    15661 aacgatcaaa tagctagttt aatgctagat aagttgacag aaaatggcta tcatattcca
    15721 gatgacctat cgatcgtagg aacagacgat tcttctttaa gccatttagg gaataaaaaa
    15781 ttgacaacat tgacgcatcc aaaagaaaag ttgggacaag atgccgcacg gtggatcgtc
    15841 acaacgattg aaaaaggaca ggcacagcca aatattctct atgaacctgt actagttgaa
    15901 cgggaaacag tgaaagaaaa cgaaaaataa gagacgggtt tttaccgcct cttattgctc
    15961 ctacggttac tcgtcgcaat gtttgtgaga gcttttgtca tcgctcaagg ctgaacgttt
    16021 ctttcaccac ctctccacta aacggtgttc tcctaccaac tggtcacaag tcacaatatt
    16081 catcaaacat gagaagctgt tttttgaaat tgttccttgt gactggaaac taagcggttc
    16141 cttcttattt cttgaagctg accacttctg tcacaacctc tttaagaatg atggatagaa
    16201 atacgtttag gataagtttt tttagatgca ctttgttcga tttcctctaa agatttccca
    16261 cgagtttctg gtacgatctc ttgaataaat aaaaccccta aaaagcagat gatcccaaaa
    16321 atgccgaaaa cgatttcttg agacatagaa gcagtcatca caggaaaaag caagccaact
    16381 aggaaagaac caatccaatt aaaagaagag gctaggccag atgctcgccc gcggacagct
    16441 agtgggaata tttcgcctac gattacccat gtcagtggag cccatgtgca agaataaaat
    16501 gcgacataaa tacataaaaa caagagaatc aacaacgaat ttgtatgagc atccagtaca
    16561 gttcctaaaa cagctggtag gatgaaagaa agtcccatca cgctaccgcc tattttcaat
    16621 aaagttcgcc gattgaactt gtctgcaata accaaaaaga gcaaagaacc agcaactaaa
    16681 atgattcctt ggatgatcgg ccacatcaat gcatcgctcg ctgcatgccc agtcgctttt
    16741 tctacgatca gcggaatata gtaaaaaata gcattagctc cttgaaattg ctggaatact
    16801 gctacaccaa taccggcaat gactaaggaa cgatattttt ctaaaaacaa agtatgccaa
    16861 gaagttccgg ttgtcttttc ttgtttgaca ttcagctgga tttgttcgaa ttcctgttca
    16921 gcttcttttg gtgtccgaat atagttcaat actctttttg cctcttccaa gcggccagat
    16981 tgcataagaa aacgcggtga ctctggtaga gctaaaacac cgaaaaataa aatcagcgcg
    17041 gggacagcag cgagccctaa catcacgcgc caagccatcg tttcaggcaa cccttttagc
    17101 aaataatctg caacatagga aaggagcatg ccagaagcaa tcatcacttg attgatccct
    17161 gacaatcttc cccttagtct agcaggagcc atttcagaca tataagcagg aactagggca
    17221 gatgcagcgc caacagctaa acctagaaga atccttgctg caatcagaaa ataagaacca
    17281 ttgtgagggg cagatgcaga aaggacagaa ccagccataa aaataagtgc agaaagaaga
    17341 atcatttttc gtcgtccaag cttatcagaa agaagaccag ataaagagcc gccaaggatc
    17401 gcacctaaca tgaccgaaga cgtgatccat cctatcaaag aagctttacc tgccaaaccc
    17461 caatcatgct gtaaaaaagg taaggcgccg gtcataacac caatatcata tccaaataga
    17521 atgccgccaa atgcgccaaa aaaataaata aacgatgagg aaactttttt ttcttttttc
    17581 ataagtattc tctccttcta gaatttcgag aaggcggttg atcagatttt gtaagcaatt
    17641 tcattttata acttatgtac gtacaaaaca agtgtttttt attgtattct tgtaaataac
    17701 tgcttgacat gtacgtacaa aagtatacaa taatcattgt aagcgctact aaaaagacgg
    17761 tttgatcagg tttgacgaga aggagggagt taaatcatta tgaaggaagt aaatgcgcaa
    17821 agtatgttag atgtcataga tggtcgtaca tctttaggga ttgagtttgg atcaactagg
    17881 atcaaagctg tattgattga ttcatctttt actcctattg ccgctggtag ttatgagtgg
    17941 gaaaacaaac tagaaaatgg tatctggacc tattcattag aagatatttg gaaaggactg
    18001 cgcgtcagtt accgaaaaat ggcagcagaa gtattcgaaa tctatggcga gaatcttacg
    18061 acaatcgggt cgattgggtt cagtgcaatg atgcacggtt atctagcatt tgatagcaag
    18121 gaacagttac tagtaccatt tcgtacttgg cgaaatacaa tcactgaaga agcagaacga
    18181 atattaacgg aaaaatttca atacaatatt ccgcagagat ggagtatcgc tcatttgtat
    18241 caatctattt tgaataaaga agaacatgtg aaagaaatta attttttgac aacgcttgca
    18301 ggttatgtcc attggcagct tactggtgag aaagtactag gcgtaggaga tgcatcaggc
    18361 atgtttccta tcgatccttc aacgaaaacc taccatcaag aaatgaaaaa tatttttggt
    18421 cagttaatcg aaaaagcgca cgtagcgatt gacttggatc acattttgcc taaagttcta
    18481 gtagcaggag aagaagctgg caagttaagc gaatcagggg cttatctgat cgaccctacg
    18541 ggaaatttga gaccaggaat cccggtttgt ccgccagaag gggatgcagg aaccggtatg
    18601 gtcgctacga acagtgtagc caaagggaca gggaacattt cggctggtac ttccgccttc
    18661 gctatgatcg tattagaaaa agaactagaa aatgtccatc cggaaatcga catggtcact
    18721 acaccttcag gagaactagt aggcatggtt catacgaata actgctcttc ggatatcaat
    18781 gcttgggtca gtatttttga agaatttacc aattctttgg gtatggagat aagcagagat
    18841 aaattattca cggtattatt caacaaagcg ctagaaggcg atacggattg cgggggatta
    18901 ctttcttatg gttatttttc cggtgaaaac attacaggag taaatgaagg aaggccatta
    18961 tttgtacgta caccaggtag ccgttttgat ttagcgaatt tcatgcggat ccatttagcc
    19021 agtgcttttg gtgcaatgag aatcggaatg gatatattga aatctgagaa tgtccaaatt
    19081 gatcgtttag tggggcatgg ggggattttt aaaacaccag aagttggaca gcggattcta
    19141 gcatctgcta tggaggcacc agttacagtg atggacacag ccggagaagg tggagcgtgg
    19201 ggaatcgcgt tattagcagc ctatatgatg gatcgacatg ggaagtcttt agaaaacttc
    19261 ttggcagaag acgtgtttgg acaagaccaa ggaatcacca tcacaccttc agcagaagaa
    19321 atagcaggct atcagatatt tatgagacgt taccgtgagg ggatcgacat tgaaaaaaca
    19381 gcgattcatc aattgcaaga aaaaggagtg atagaaaatg ctggaacaac tgaaagaaga
    19441 agtataccaa gcaaatcttg acttgcctaa acacggactc gtcaaatata catggggaaa
    19501 tgtgagcgct tttgatcctg aaacacgata tttcgttatc aaacctagcg gagtcagtta
    19561 tgaagagatg acagcagacg acatggtcgt tgtggacttg gacaatcata tcattgaagg
    19621 taaactcaat ccctcttcgg atacgcctac tcatgctgtt ttatatcgtt catttcctca
    19681 aatcggagga atcgtccata ctcactcgac atgggcgacg atctgggcac aagcaggatt
    19741 ggatgttcct gcgatgggga cgacgcatgc agatactttt tatggatcgg taccttgtgc
    19801 tcgatttttg acacaacagg aaatcgacag cgggtacgaa tatgaaacag gaaaagttat
    19861 catagaaaca ttcaaagaac gcaaaattga tcccttagca attccagggg tacttttaca
    19921 cggacacggt ccatttactt gggggaaaga tgcgcaaagt gcggtaatga acgcagtcgt
    19981 actagatgaa gtatgcaaga tgaatttatt taccagacag ctcaattcat tttcagaaga
    20041 gctgcctcaa cggattttag ataaacatta tttacgaaaa cacggaaaaa atgcgtatta
    20101 cggacaaaac aaataaaagg agtggctaat tatgttgaat attggagaaa aagaattttg
    20161 gtttgttgta ggatcacagc atttatatgg ggaagaagca ctgcgagaag taaagaaaca
    20221 tgcacaagaa atggtcgatg aactgaatga aaatggccaa ttgccttatc caatccgcct
    20281 tcaagaatta gcagttactg ctgatacgat cacaaaaatc atgaaagagg tcaattatcg
    20341 agaagaagta gcaggtgtga tcacttggat gcatactttc tcaccagcaa aaatgtggat
    20401 ccgcgggaca aagcttctac aaaaaccatt gcttcattta gctacgcaat ataacgaaag
    20461 cattccttgg aaaacgatcg atatggattt catgaattta aatcaatccg ctcatggtga
    20521 ccgcgaatat gggttcatca atgctcgatt aaataaacaa aataaaatcg tcgttggcta
    20581 ctggaaacga cctgagatcc aaaaagagat tgctgattgg atggatgttg cagtagccta
    20641 taatgaaagt tttggaataa aagtggctcg ttttggtgac aacatgagaa acgtgggtgt
    20701 cacagaagga gacaaagtgg aagcacagat tcaatttggt tggactgttg attattttgg
    20761 tatcggagat cttgtacaag taatcgatcg cgtatcagac gaagaagtcg atcaattatt
    20821 tgaagagtac aaggaattgt ataccttcga ctatggtgat tatgaagaaa agacatggga
    20881 ggaacatgta aaagtacaag ctcagcagga aatcggtatt cgccgtttct tagaagaagg
    20941 aggctataac gcttttacga ctaattttga agacctgtat ggaatgaaac aactacctgg
    21001 actagctgta caacgtttga tggcagaagg atacggtttt gctggggaag gcgactggaa
    21061 aactgcagcg attgatcggt tgctgaaaat catggctcga gggaaagata caggattcat
    21121 ggaagattat acttacgagc tagctagtgg ccaagaagca atcttggaat cccatatgat
    21181 ggaagtagat ccgacgcttg ctgcgacgaa accaagaatc gttgtttctc ctttatcaat
    21241 gggagataga gaagatccgg cgcgtcttgt atttgatggg aaagcaggag aaggggtagt
    21301 cgtatcgatg gcagatttcg gtacgcatta taaactgctg atcaatgaag tagaagcctt
    21361 tgaaccaacg actgaagcac ctaatttacc tgttgcacgt gtgttatgga aaactaaacc
    21421 gaatttccat gaaggtgtcc attcatggat tcaggcaggt ggcggtcatc ataccgttgt
    21481 ctcgctaaat ctaacaacag atcaaattga aacgtgggca aaattagttg agttggaaac
    21541 agtggttatt agataaaaag aggttgtgaa aaagccactt agttttaaga aataagaaga
    21601 gattgacgaa atttgctttt caactttttt gaaatttagt cttattatca atgtcagcta
    21661 acggaacacc atttatcaag atatctcacc ctcaatattt tgctctcgaa aataaggctt
    21721 atggcagtaa cttgtcatag ccttattttt atcactcagc ctactctgct ctaactgctc
    21781 tttttgcttc taggaagtca aatggtaaac agttgtctaa ttgcagaaat ttcgagatac
    21841 ttgttagtaa ggagggggtt ttatgtatca cgttcatttg attgatgcta ttccagaaca
    21901 agagatagaa aagttacaag gggaatattt caaaataata gatgatttgc cagccgaagg
    21961 aatagttatt cgtagtacga aagtgaaaga tgaatggctt acaccagatt tgctagcaat
    22021 ttcaagagct ggtgttgggg tgaacacgat caacgttgaa aaagcttctg aaaacgggac
    22081 gatcgtcatg aatacaccag gtgtaaatgc taatgcagta aaagagcttg ttttgtgctg
    22141 tttgctctta tcttcccgtc cgataatcga agcaagtcgt atggtacaaa cactaacagg
    22201 tcctaatatt ttagaacagg cagaaaacaa aagaagtgct tatgtgggac gagaattgca
    22261 aggcaaaacc atcggtcttc ttggtcttgg agcgataggc acaaaagtag cgctaagttg
    22321 ctatagctta gggatggatg tcttgggtta ttctatccgc gatgcccagt tggattatgt
    22381 tcggcaagca gatttagaaa cagttctttc tacctcggat tacatcgtag tcatgctgcc
    22441 gttgacagaa gatacaaaag gattgatcga tcaggcgaat atagaaaaaa tgaaaaaaga
    22501 tgctgtactt atcaatgtag gaagaagtga aattgttgat aaatatgctg ttatgcaagc
    22561 attggaaaaa caacatctgg ctaaatactt gactgatttt ccagaagaag agttcttaga
    22621 aaatgaccgt atacttatgt tgcctcatct aggggatcga ctcaggaagc tttggcagac
    22681 agcggacgtt tggcagttga agccttaaaa gattatcttt tgttcggtac ggttagagaa
    22741 gcggtcaatt atccatccgc acgaatgttt ttccaagcgc cgtttcgatt cactatattt
    22801 tatcaaaaga aaaccaatat attagcagag atattttctc tgctgaatga gaacgagcta
    22861 gcgatcgcag atatatcgcg taaccataag aatgagcatg tctacatatt gattgacata
    22921 gacagtactg attttgaaca gctcaatcaa gtgaaacaac agctagaaaa aatttctgga
    22981 gtacgaaagg tccgcttatt aaagaaacca gaaaggccat aaagaaagag aatatttgga
    23041 tttcattaat tcttctttcc gttctttact ttcgaatttc gtacaactaa aataagagaa
    23101 gcaacattct tttattgata gaaatgaagg agcaagcatt tgaaaagata tataagcaga
    23161 ctttcgacca aacagaaaaa gattttaaaa ggaacagcag caatcatcag tatctttttt
    23221 cttgttgttt ttagtaattt atttttgcag tggtgtcaaa atgatctatc cgtagacctt
    23281 gcgttgaaat ttgctttttc ttggcatacg gaaaaattct tcttagcctg tctcgtcttg
    23341 ctgattattc ttatttttct gattgcacta gcaggatctg tccctttagg ttcccttacg
    23401 tatgtcgtag ccatcggtgt attaggtttt gcaaattata tgaaaatgag ttatcggcaa
    23461 gaaccgattt atccagacga tttgaagatg atcactgaaa tcggattgct gaaagatatg
    23521 accggcacta tgctgtttac agtgatctta gctgccgcag gaaccgtgat aggattgttt
    23581 tgctggtaca tgtttcgaag cctgaaaaaa ggaaggcgat tccaattgat ccgattaacg
    23641 acactgcttg tggcaattgg actgctaggg tatatcagta atttcaacaa tcccgataat
    23701 ttgttgcgaa aagcatataa taaaacggca ctatggatac cttacagcca gaaaatgaac
    23761 tactataaca ctggttttat cggtgggttt ttgtacaatc tgaaggtaga accaatggat
    23821 gaacctgaag gatattcgaa agaaaagatc aaagaaatca ctgaaaaata ccagaagcta
    23881 gccgatgaaa aaaataaaac tgtagaggaa gagtcgccga acatcgtgtt cgtgatgagt
    23941 gaaagtttct cagatcctag tcgattaaac ggcgtagaag tatctggtga gccattggca
    24001 gattattatg aagtagctga tcaaacatat agtggcaata tgctttctca aaactatggc
    24061 ggtggaacag caaatatcga atttgaagca ttgactggtt tttctatggc gttatttaat
    24121 gcgcaactca ccacccctta cacgatgctt gtaccaaaaa tggatcagct tccttctatc
    24181 gtttcagcgt taaacgcaca atcataccag acgacagcga tccatccata caatacttcg
    24241 atgtataaaa gagaggatgt ttatcagaca ttaggatttg accagttcat cagcgagcgt
    24301 acgatgacct atacggatac gatagagaat aatccatata tttctgatga gtcagcttac
    24361 aaagaagtaa tgacacttct caaggaagaa aaaacacctc agttcattca tttagtcacg
    24421 atgcagacac atatgcccta cgatggaaag tatgataatc tagactatcc tgcaaaaact
    24481 tcagatggaa gtgggacact tgacttagag aattatctgc aagatatttc ctatagcagc
    24541 acggcactga agcagttcac ggaagaattg aagaatcttt ctagaaggac tttagttgtt
    24601 ttttgggggg atcatcttcc agggatctat tcagatacga tccaagcaaa aaatgacaaa
    24661 caaacattgc atgaaacaca atttcttatg ttcgacagta aaggagaatt agaaaagcaa
    24721 acgactcacg atgcaatcac cagtccgttt tattttgcag cgaatctaat ggaacagacg
    24781 aatcagacaa caaatggctt ttatcagctg cttttatcat tagaacagga acttccggcg
    24841 tttgaacgag aactgtacta tcaaaacgga cagtggtata aagaagcgca attcaatcgc
    24901 tcgcaacaag agatttacga cgaatatcaa ttgatccaat atgacattgt cgcagggaaa
    24961 caatatagtt tagcagatgg tttctttgag cacgaataag aatggcgagc tgtatagaaa
    25021 ccattaaatt ttttcaagta cttgtcattt gaggataaaa acaagtagaa taaataataa
    25081 caacaatgga gaaagtagga aaacgaacat gttaccgaat attggctatt atgtgcagtc
    25141 catcgatcaa atcgtcaagg aaacagaagc aatcggagaa ggaatgcatc cgaaatatga
    25201 agtgatcaga aacgcaattg atgaaggaaa aacaagtgaa ctggacaaat cgactcttga
    25261 agagatcatc ctgttatttg aagaaggaac aaaaaaatat cgggcaatgc ttatgaaagt
    25321 cagtactttg cgtccaccag caaaagcaat gggcattcat aaaaattttg aaaaagctta
    25381 tctttcatat gtagcaggct gtgaagaaat gatccaaagt atcgatcttg aatcaggggt
    25441 agatgaagat ctattcaata catctgaagc aaaacaagac caagcgacag accaattgac
    25501 agctgccatc caaaaaatga ctaatttgtt gttgaaaaaa taaaagaaat ctttgataac
    25561 aataaaaact agagttatct aatataaatg taatattacc tttatgatag agtgatcaaa
    25621 atcctttatg ataatgacat acctataacc aacaacaacc ttgtacttac tcaaaatcga
    25681 gtaaatactc cttttccgtc gagtctaacc atctcggcgg ttttttattt gtagaaaaga
    25741 acatcaggat agacggaaaa gtcttgtcct gatgttcttt tcagatagta tggaaagctg
    25801 attagttttc tacattctgt acatattgtt caaagtagtt ctgtaaatcg gctttgagtt
    25861 tctgatattc ctcttcgcta tactctttat cttcgatttt cccatcaaag aaaggaatat
    25921 ttagttcttc ccgtagtctg tctaatacgt cttgctgatt catttcattc tccttttctt
    25981 actaacgatc aaaataaaca cagacacatt ctggtacata gacatctttt ttcagtaatt
    26041 ccagtaatcc tgtttcagga tgacggcgat ataatgtcag attatcggtg ttctgattgg
    26101 cacacacgac aaaattattg cttggatcta gtgcgaaatc gcggggaaaa tccccttctg
    26161 ttgagatgat ttgcttgttt tgaatgtggg aaccatcttc aaaaactgcg aatacagcaa
    26221 tcgagttatg tcctcggtta gaagcataaa ggaacttgcc atcatttgaa atgcggatag
    26281 ctgcccctcc attttcaccg tcgaattctt ctggcaaggt cgatattttc tgtaattctt
    26341 caaaagcacc tgtttcttta ttataagaaa gcacgcggac tgtgctgtct aattcaccaa
    26401 ataaataagc gaattgtcca tttggatgaa agacaagatg gcgagggcct gttcctggct
    26461 ctgcagtgaa ggtagttaca agattcaatt tgccgttttc ggacacatca taagtataca
    26521 cacgatctgt accaagatca catacgacta atcgttggtc aggagtcaga tccgtatagt
    26581 ggacatgcgc atgatcttgg tttttatgag gacctgtcgc ttcttgatgg aatattgaat
    26641 ctgctgcttt cagttcgcca tctcctaata tatggtagac atttacttca cctttatgat
    26701 agttcgcccc gtatagtaat tgacgtgctt catcaaccgc tacataacac aaaggagcgc
    26761 cagactctgt taccgcattc aaaaaatgaa aatccttatc gtacgcaccg gcaccaccta
    26821 atccatccac actagtaact gtgtaaagat tgccagcttt actttttgct acataggtag
    26881 ggctattttc ttcaacagct aatgaaaggt tggctaattc ttctttttct gtatcaaggt
    26941 cgatcgtata gattccttta ctttcgcgac gcgtataggt tcctaaaatt atcttttcga
    27001 tcatatgagc tgattcctcc taattgtaat gaaatagttt tcgtttttat tctatcacat
    27061 aattattcca cacggctaaa gaatgagaat gtgttatact gtttttgaaa gcaattaaag
    27121 gagagagtgc aatgattcag gcaaagatta cagaaattgg gacagaagca ataaacaagg
    27181 aagaacccat gctgattttg ttcgataaaa cagcaacagc tgccttacga aaatattcgg
    27241 tgattcaaga agtatcaaaa gacgaacctt tttctttgaa agcaggcgga acaattgctt
    27301 ttgatgatca ggtatatacg atcgattatg tcggtccgat ggccaatggg aatttaaaga
    27361 cagtagctca cgtatcattg atttttgatg cttgtccaga agaaggacaa attgcaaatg
    27421 gaatctatct tcatccgcat agactgcctg ctattggttt gggaagccaa attttttata
    27481 actaacagga ggaattatgg aaggaaaaaa taagaagaac agaccggtat cgtggttttg
    27541 gcgctggttt ttaaataatc aagtagtcac agccttactt gttgtattgt taatattgct
    27601 gatcgtcttt ttatttacaa aagtttcata tttgtttgca ccaatctggc aatttttagc
    27661 aatcgtaggt ctgcctatca ttttagcagg aatcttgtat tacttgatga atccggtagt
    27721 tgattacttt gaaaagcgaa aagtaccaag gctttacagt atcattgggc tgtttgtttt
    27781 ggttgttgca ctaatcgcat gggggagcgt agtgatcatc cctaagattc aggaacaaac
    27841 agtgagcttc atcagtaact tccctcaata tgtagatacg attgataata aattaaccga
    27901 gattttgcgg gacccgctgt tcaaccaatt tcgcgaacag ttggaaacag caggtgataa
    27961 gttcatgaat tcggcaggcg atatgatcca agatatatct aagagtacag ttcagagtct
    28021 tggaagtttt gtcggcgcgg tagcgactat tttagtggct ctgctgacga tgccgtttat
    28081 cttattttat ctattgaaag acggtaaaca attagcacct tattttgtca aatttttacc
    28141 gacacgcatg caaaaaccga cgttgaatgt gctgagtgaa atgaatagtc aagtttcttc
    28201 ttatataaga ggacaactaa ctgtggcttt tgctgtggca atcatgttta tgattggttt
    28261 tgcggtcatt ggtttagagt atgctgtcac gttggggatt attgcgggtt ttttaaacct
    28321 gatcccttac ttaggatcat ttttagcgat gattccggct atctttttag ccattgtagc
    28381 aggtccattc atgatcatca aagtactgat cgtttttgca gtagagcaga caatagaagg
    28441 acgcttgatc tctccattag tactagggaa tcagttagca atccatccag taacgatttt
    28501 attagttctg ctgacttctg ggaaattgtt cggaatcatc ggtgtgatct tggggattcc
    28561 tgtttatgca gcagctaaag tagtgattac tcatgttttt gaatggtaca caacaatctc
    28621 ttctctttat gaagaaaatc cgttgaaaaa gcagaaagaa taacaaaaag agacagatgg
    28681 gaaaatatcc aaggcacaaa tgctgctttg aagatttttt cctctgtctc ttttgtatgc
    28741 atttatctca atttttaaaa tgatttacct aaagcagcag ctttatctaa tgcattttgc
    28801 atcaactcat ctgcacggtc agggtcataa tcgattcctt cgatgaatag ctgatctact
    28861 tgatcgatgc ctacaaagtt taaaatacct tttacatatt gagaggcaaa gtcttgtccg
    28921 ttgtatacac cgccattaga ttggatgtgc agtgcttttt tacctgtcac taatccttct
    28981 ggcccgtttt ctgtatagcg gaacgttttt ccagctacat tgacggtatc gaaccaagct
    29041 tttaattttg ttgggatatt tagattccat aaggcgtttg cgataacgat tttatcagca
    29101 gcaaggaact gatcagtcaa ttcattgaaa cgagcaattt tttgttgttg actttctgat
    29161 aaggaagtga attctgcacc agcacgtaat gcttcccaac ctgataataa ttcttcatcg
    29221 atttccggaa tatcatcgcg ataaagttcc aaaacagtca cttcatcatc tggatgattt
    29281 tctttataac ttgttaaaaa agacgtcaat gccttaactg tgcgcgattc ttctgcagtt
    29341 aggggatgac ctttgactac taaaacagat gccatatgct taccttctcc ttttattgct
    29401 atgattgtta taactatgac taacaaaatc agtttactcg aaaaagaaaa ggctatcaag
    29461 tcatattgat aaggttgaag aataaataac taaaaaaaga cagggtataa aagaggctgt
    29521 gacacgattt tttgtcacag cctcttttga atctaacaag caatattcaa gcaacactcg
    29581 actgaagagc ttccatccca ccaatgatat aaacagcacg aaaaccatta gcagtaagtt
    29641 gatcggctaa tgcttctgat cgcctgcctg tatagcttag aatataataa agtttctttg
    29701 gatctagatt ttttaattgt cttggcaaga tagcagcggg gatagaaagc gagtggctta
    29761 agtggttttt tgtgtaatct aaggtatttc ttgtatctaa aacgatgctg tcagcatcga
    29821 gaggcaattt attgaagtct tggacactaa ttgattgggc catttatctc atcctttgtt
    29881 tagtatgtgg ctattttaat gggcaactct cattaattca aatggaagga ttcctcttat
    29941 cactttttta atgtatcgga tgataatgaa aaaaactatg caaatgtctt gcaaaacagg
    30001 taggaggtgt tataatgaca tagcgtcata tgacaatgtg tcatcttgaa agaaaggaga
    30061 atccatatgc cgacacagac atttttccat ttgcctaaag aaaaacaaaa aagactaatc
    30121 gaggctgcga gaatcgagtt ttctagagta cccttaaaag aagcttcgat tgctaatatc
    30181 gtcaaattag cggatatccc tagaggcagt ttctatcagt attttgaaga taaagaggat
    30241 ctttattttt attactttga gacaatgaga cgtgacagct ctaaagatat gttacaacta
    30301 atgaaagaat ccgatggtga tctattcaaa ggattcgaat cctatttttc taaaatgatt
    30361 tatgagattt tggaaggcga gaatgcttct ttttatcgta acttgtttat gaacatggat
    30421 taccgtgcct caagaaaagt cgctcctcat acgagtcgcc aaaaaacgcc tcacgatcca
    30481 cataaagaac acaaacaaga tgcaaaagag ttgcttgaat tgatcgatcg gacgaagctg
    30541 aaagtaaaaa atgatcatga attggaatta ctgatccaat tagtgatgaa tactgtattt
    30601 acaacaattg cgcattcgta tcgcttattt tcaacatctg aagattactc agtagagcaa
    30661 gcaatcagtg aattcaattt gaaactttct tggctgaaaa acggagtata taaatagaaa
    30721 gaagggaact agatgctaaa aatcgtaaaa cggatctcct tgacttcagc aattgcagct
    30781 gcagttttca tggtgatcca agtactggca gatttatatt tgccgacact tacctccaat
    30841 attattgata aaggggtagc gcaaggagat gtcgattata tttggcatac aggttttgtg
    30901 atgatcggct tttctttgat cagtatctta gctgctatcg caaatacatt ttttgctact
    30961 cgtgaatcac agaaactggg taagcaattg cgtacggatg tctataaaaa atcagagagt
    31021 ctgacaaaag atgcgtttga taaatatgga acggcctctt tgatcacaag aacgaccaat
    31081 gatgtgactc aaatccaaat ggttacacaa atgtttttac gtatgatgat caatgcacca
    31141 atcacgttga ttggcgcgag catacttgct tatcaaaaag atcatcagtt gacaaaaatc
    31201 ttcttagttg tcatcccagt aatgattatt ttgatcggcg gaatcatgta ctttgctgtt
    31261 ccattattca aaagtatgca aaagaaaact gaccgtttaa acctggtatt tcgagaagga
    31321 ttgacagggg tcagagtgat tcgagcattc gataagacac gctttgaaga aaatcgtttt
    31381 gatttagcga ataaagatta tacaaatacg gcaatcaaag ttaatacgat cgtcgcattg
    31441 atgatgccaa tgatgacatt gatcatgagc ggtacaaacg tagcaatcac ttggtttggt
    31501 ggacactaca tagcagatat gactttggaa gtcggtaatc tgattgcatt tatgacttat
    31561 gcgatgcaga tcttgatcag ctttatgatg ctttccgcta tttttatcat ggtgcctcgt
    31621 gcacaagctt cagctgaccg tattaatgaa gtgttggatg aaaaaatcgg tatccatgac
    31681 cctgaaaatc ctaaaacagt ttcttttgct ggaaaaaacg caacattggc cttcaatcat
    31741 gtcaattatc gatatcatgg agcagaaaaa cttgcattgg aagatattga tttccaagcc
    31801 aagtcgggcg agatcgtcgc aatcataggg gggactggtt caggtaaaac gaccttagtc
    31861 aatttgatcc ctcgattata tgacatcgaa tctggttcga tccaaataaa tggaacggac
    31921 attagtgaca tgactcaata taatttgcga gaattaatgg gctttgttcc tcaaaaagca
    31981 gttctgttct ctggaacgat ccgagacaat atgcagtatg gtaagccgga tgcaacagat
    32041 gaaatgattt ggaaagcatt agaaatcgca caagctaaag attttgtttc agagatggaa
    32101 gatggcttag atagccatgt ggaacaagga ggaggaaact tctctggtgg acaaagacag
    32161 cgtctggcaa ttgcacgggc attagtcaaa acagcagata tctatgtgtt tgatgattcc
    32221 ttctcagcgt tggatttcaa aacggatgcc aatcttcgcc aagcattgaa aacgaatatg
    32281 aaagaaagta tcaccgtttt agttgctcaa cgagtaagta cagtaatgga tgcagatatg
    32341 atccttgtgc tagatgaagg aaaactggtt ggcaaaggaa cacatgaaga actattagca
    32401 acaaacgaaa cttatcaaga aatcgttcat tcacaactaa gagaggagga cttagcatga
    32461 gtaaaacaaa cacacgtccc tctcatggac cagcaggcgg tccaggacat ggtggacctg
    32521 gcagaaatct cggtgtaaaa ggtgaaaagc ctaaaaattt ctggggaacg gtacgccgat
    32581 tgtttggcta tatgtctaaa cgtatggttg cgatcatcgc tgtatttgta ctagcaatag
    32641 cagccgtgat cttccaaatc caaacaccaa aggtcttggg gaaagcaacc acagaaatat
    32701 tcaaaggtgt aatggctggc gctcaacaga tgcaacaagg ccaacaagta acaaaatttc
    32761 cgatagactt tgataaaatc gcgcagatca ttgcgacagt aatcgtgatg tatttgattt
    32821 ctgctgtatt caacttttta cagcaattta ttatgacacg tgtttcccaa cgaacagttt
    32881 atgaattacg tcatgatttg gaagccaaaa tgaatcgtgt accgatttcc tattatgata
    32941 cacatacaaa tggggatatc atgtctcgag caatcaatga tatggataac atcgcaagca
    33001 cgctgcagca aaatttgact caatttgtaa ctagtgcagt cacattgatt ggggtcatcg
    33061 tgatgatgct ttcaatcagc tggcaattga cgttagtcgc gttattgatg atccctttaa
    33121 gcttgatcat cgtgatgatc gtagcgccga aatcacaagt gtttttcgca gatcagcaaa
    33181 aaagtttagg tttattgaat aaccaagtag aagaaacata tggtggtcat accattgtta
    33241 aaacattcaa tcatactgaa aaagaccagg aagtatttga aaaagaaaat cagaatctgt
    33301 atgccgctgg ttggaaagct caatttattt cggcaatcat catgccgttg atgaatttcg
    33361 ttaaaaatct aggctatgtg ttcgtcgctg tactaggcgg agtaaaagtt gcaaatggga
    33421 acatgacatt aggggatgtt caagcgttct tgcaatatac aacacagttc tctcaaccaa
    33481 tcactcaact tgcaagtttg atgaacacta tccaatcaac agttgcttca gccgaacggg
    33541 tatttgaagt gttggatgaa gaagagatgt ccaatgaaaa atctggcctt ccagaagaaa
    33601 aagatacacc atacaaagtt cgttttgaaa atgttcaatt cggctacaca ccagataact
    33661 tgctaatgac tgattttaac ttggatgtca aacctggtga gatggtcgct attgtaggtc
    33721 cgactggtgc agggaagacg acactgatca accttcttga acggttctac gatgtttctg
    33781 gaggtagtat tcgttacgat ggtgtagata cccgtgatct ttcacgtgat gaattgcgcg
    33841 cacagttttc aatggtactg caagatactt ggctgtttac aggaagtatc tatgacaata
    33901 tcaaatatgg gaacgacgat gcaacagacg aacaaatcat tgaggctgct aaagctgctc
    33961 acgtagacga ttttgttcgt aaattgccag aaggatataa cactgtatta aacgaggatg
    34021 caagcaatat ttcgcaaggg cagcgtcagc taatcacaat tgcgcgggca ttcttagcaa
    34081 atccagatgt cctgatcctt gatgaagcaa catctagtgt agatacacga acagaaatac
    34141 tgattcaaaa agcgatgaac cgcctattgg aaaaccggac aagtttcgtt gttgctcacc
    34201 gcttgtctac aatacgcgat gcagacaaca ttattgtgat gaatcatggt tcgatcgtag
    34261 aaacaggaaa ccacgataca ttgatggaaa aagacggatt ctatgcagat ctttataaca
    34321 gtcagttttc tgaagaagaa gcttcataga atagtacaaa tttattattt tttttagggg
    34381 ctgtgacaaa agtcgtgtca cagtcccttt ttccgaataa acggtgttca atcagctgtc
    34441 cttcggtatt agctcaaaaa acggcaaaat atgagaagct atttttccgt tttgtatctc
    34501 taatactcag gtcaaaccgc tgattttaca acctcttcct taaacggtgt tctcctgcca
    34561 actcctcggt cacaagtcac aatagtcaac aaacctgaga agctgttttt tgaaattgct
    34621 ccttgtgact cggagttaaa cggcaggctc acaacctctt ggtaaacggt gttcaaaagc
    34681 cagtttctcg gtattaagcc aaatttatgc aaaaatgtag aaagccattt tcacaaaatt
    34741 tttcttacta ctcgaaacta agcgactttt tcacaacctc ttccttaaac ggtgttcaaa
    34801 agcttgcatc tgcggtaata agcccaacca aacgaaaaat aggaggagct atttttgttt
    34861 ggctgttctt attacttgat gcagaacagc tttttcacaa cctcttttta taagagtttt
    34921 tactcattaa tttacaaaaa acaagcaaaa tgcgaatttt ctcacatttt ttttaacaaa
    34981 atcaaagtta ttgcttgaaa gaagaagaat ccatcgttaa aataaagctt gacgtagagg
    35041 ggagcaagaa atatgaaaga ttttcaattg ggggctgcca cctatttaaa aagtgtagcc
    35101 attcgggtga aagaccgaga taaaatgatt gatttttaca agaacgttgt tggctttgat
    35161 ttgaaaagag aagaaaacga attagccatt ttaggaacag aagaagctgg aagtgaaatg
    35221 ttgctgctgg aagaaagtcc tagagcgaat gatcacatgg gggtgatcaa aaagctgaac
    35281 cgtttttcat tgattatccc tagcacagaa gaaatggcag atatcctttg tcgtatccgt
    35341 aaaatgaatt atccaatcaa agaagcttta gaagatcatg gacgtatggg gattttgctc
    35401 gtagacccag aagagaatga attggaaatt taccatgaag agaataagaa cgaccaaaga
    35461 gaaattccag aaacaatgga tcaagaagca ttattaagaa aatctgaaga aaaattcagt
    35521 aaactatcaa caggttctta ttttgaaaaa atccatttaa atgttactaa cttaacaaaa
    35581 gaacgccaat ttcttaatca tgtacttggt ttgaaggtac ataatgaaga agagggcatc
    35641 catgtattga atgaaggaga tttccatgtt ggtttgacag aagctagcgg aggcgcaatt
    35701 gatttgccta cagatgaagt gattggactt gattttctga aattcatgat cgatactgaa
    35761 agcatggaag gactgattgc tcacttgcag caactatcag ttgatttctt cttagacaaa
    35821 aagcacacag tactcacaat ctatgatgct ataggaatcg aatggtggtt cgtcagtgag
    35881 ccaaaagaaa agaataaaac tgacattcga tgcgacgctt aactttttct ttcttaacga
    35941 ttgtcgcatg tctcgtcatt ttatgaacgg tcatactatc gcttattcta gagatagaaa
    36001 gagaaaatag tataccgggg gaaactgcgc ggtttttcgc gcagtttttt tgtgtaaaaa
    36061 aggttgattc ctcatagatt aagctttaag cttggactgt aagaatctga tagaaaagca
    36121 ggagaaaaag atgtatccac acacgaaaca gcttattttg aaaaagatgg aagaaggatt
    36181 ttatccaggt gtagcagtcg ccttcataaa agaaaatcaa gtagaaacat ttacagccgg
    36241 ctttgcccaa gtcgttcctg aaaagcagct gatgacagaa gatctgttgt ttgatgcagc
    36301 ctcactgacg aaagtcgttg caaccacttc attagtttta cgtctattag aagatggaaa
    36361 gatagaactc gatcaaccgc ttcataaata tcttcctgaa tttgaaaatc agacaatcac
    36421 tttgcgtcat ttactgacac atacttctga tatcaaaaca tggataccaa acagagataa
    36481 gctatctcag gaagaattga tcgccgctta tttgaagcta gaaccaggtg agcaactagg
    36541 aaaagaagta aaatatacag atgccggtac gattcttctt gggttgatgc tagaggaaat
    36601 ttaccaagaa actgcagtgg aaatctttca agaacaagta ttggaaccat taggaatgat
    36661 gaacagctta tttcttcctt ttccttccaa aaaaatcgtt cccacagaac aactgccttc
    36721 gggtgaggtt ttgcgtggac aaactcatga tccgaaagca agagttttgg ctgaacatgc
    36781 aggtaacgcg ggtctcttta ttgatttgaa agacagcatt acttttgtcc aaatgtattt
    36841 gaacaaggga aaaatccgta atggtcgttt tttagaagaa gagacgattg attctttact
    36901 gcaagatcaa acaccgaaaa aaaatggcta tcgttcttta ggatgggact taaaaaagga
    36961 tgtagaagac ggtcatgcga ttctttttca tactggttat acaggtacgt ttttcttgat
    37021 tgatataaaa acacaagaag cgttgatatt tttgtcaaat cgcgtacatc ctgtcgatca
    37081 tcgtgcggag tatctcatat gtcgagatga aattgttgaa aactttttga aagagaaagc
    37141 ggtattaccg aaataatgct ataatagcta tgaaaaatga gaggagtttg aattatgcag
    37201 gaacctatgt ttttaaaacc agtttttcaa gaaaaaattt ggggaggaag tcgtttacgt
    37261 tcagtctttg gttttgatat ccctaacgat aaaatcggag aagattgggc gatcagtgcg
    37321 catcctcatg gtgtcagtgt agtagaaaat ggcgaattca aagggaaaag attagatgaa
    37381 ctatggtcag aacacaagga attgtttggc catccttcag aaccagtgtt tccattattg
    37441 atcaagatct tagacgcaga agatgatcta tctgtacaag tacatccaga tgatgcctat
    37501 gggatgaaac atgaaggtga attaggaaaa actgaatgct ggtatatcat cgatgctgaa
    37561 cctggtgcag aaatcatcta tggtcatcat gcaaagacaa gagaagaact agctgagatg
    37621 atcaaagatg ggcgctggga tgaccttttg aagaaagtac cagttaaaaa aggtgatttc
    37681 ttttatgtac caagcggaac gatccatgct attggtaaag gaatcatgat tttagaaaca
    37741 cagcaaagtt ctgacacgac ttaccgcgtg tatgactacg acagaaaaga tgcgcaagga
    37801 caaacaagag agctgcatat ccaacaatcg atcgatgtaa caactgtccc tgcgaaaaca
    37861 ccagaattac aaatcaaaga agtccgaaaa gggaattcat cgatcgtcac ttatttagaa
    37921 actgagtttt tcaatgtata tgagtgggat attaaaggaa tcacatcttt caaaaaacaa
    37981 gccccttata cattgatgac ggtaatcgaa ggagcaggag accttgtcgt tgacggaaaa
    38041 acatatccat tagaaaaagg aacaagctgt attattccaa atggcgtttc tgagtgggcg
    38101 gtccaaggtg aactagcaat cattgcgtct gaaccaggca aatagttccc agatagctga
    38161 aagcagcaga cggtttttcg tttgctgctt tttctacata aaatccgtcc atcaataaat
    38221 agaagtctgg tgaaaaagat ggaatacaaa tggaaagcaa acaacagcag tcgcgtgtct
    38281 atgaaacaac tgagaaaagc tggacatcac ttaaatgaaa tgatcatgcc aaatctaagt
    38341 ctgtttatcg cttggggaat cttgtcatta gcaacaaaag gtgtgtctgg cgatttgcac
    38401 accacattag aagaggtatg ccattggatg atccagctgc ttttacccat cttgatcagt
    38461 tattcaggcg ggaaatcggt agggggacaa aaaggggcag tcgccggtgc aattgcttct
    38521 ttagggttga tcgctcgttc caatgctcca caaatcgtag gagcgatgat tatcgggccg
    38581 cttgccggca tcgtatatga acaatttgtt tctagattcc atgtgaaatt caaggctgga
    38641 tatgaaatgc ttgtcagcaa cctactagta ggactgactg gtagcgttat ttgtataatt
    38701 ggaatcgttt ttattgaacc agttttaaat agtgttcact tgttgctcgc ctccgttgtg
    38761 tcttggctag tcacaatgaa tctgttacca cttgtcagtc tgatcttaga acctctaaaa
    38821 gtactatttt tcaataatgc aatcaatcat ggtgtattga cacctttagg aatcgaattc
    38881 tcacaaacag tcgggtactc ttccttattt ttgatggagg caaatcctgg acctggttta
    38941 gggatcttac tttctatcct ttgttttgca gaaaaacagg aaaaagtaaa tgcgagtgga
    39001 gcattgatga tccatgcgat tggcgggatt cacgaaatct attttccatt tgtcttgctg
    39061 cgaccgtatc tatttttagc tgtaatggct ggtggggcaa gcggcacgtt gatatttcaa
    39121 tggttagata cgggattagc tgcacctgta tcgcctgggt cactactcgt gatttttgcc
    39181 aatgcgcctt atccacaact agctggggta agtataggga tagcaatcag tacatttgtg
    39241 accttcattt gtgcagcgat actattgaaa ttaccaaata aagaaaaaga gaacaaaacg
    39301 gtcaaagaaa ggggagaaat cttggaacca tctatcattc attccgtcat ttttgcttgc
    39361 gactcaggta tgggatcaag tgctatggga gccgccctgc tgaaaaagaa attagcagca
    39421 gaaaaaatcg atctttctgt cggatacagc tctatctatg aattgaataa ccaagtaaat
    39481 cagctggtta tcgtgcaaca tgaactagcg ggtcttgcaa gagaaaaagt acctcaaagt
    39541 caaatctatg tactggatca ctttttggaa acagatatct tgctgtcacg aataaaagaa
    39601 gcgatccaat ttccaaagcg ggaagaaaaa aaagagatag cagatatcac agaacaaaaa
    39661 acgtcgcctg ctaatattgt atttttgtat aaaaacaaca gacgcggctc acaaactatg
    39721 ggcatgacga ttttaagtca attagcaaaa aaagcgaaaa aacagtttgt tatctcaaaa
    39781 gaatcaatag aaaaaatcaa aatccaagaa gaaacgattt atatcgcaca aagagaacta
    39841 gctgtaactg aacagctaga agaaaagatc cctcggctag ttctagttga acattgggta
    39901 gctacgaatg aatacgaaaa actcgtgaag ggagaaatat aagatgtatt tatcgcccag
    39961 agaaaaacaa ttattagcag aatttctcag tagcccgtca cctgtatcta tccaaaaaat
    40021 gatgaattta ttgaaggtca gtaaacggac tatttaccgc gaattagata atcttgaagt
    40081 ctcattgaaa tcggtaaatg cttctttgaa aaaagcagct agaggctcat ttgtcattga
    40141 ggcatcagaa gaagtattag agcaattaaa agaaaataca gatgggaaaa gtaatgactt
    40201 atccactgct aaacgacaac acgcgatttt agccgagttg ttactgacga cagagccgtt
    40261 gagtcttgct catttcatgg aatcatatcg catcagtaat accacttttt atgcagatat
    40321 caaacagttg gaagaaagta ttcgccaact gcctttggaa atcattcgga accagggata
    40381 cgagatcgaa ggaccggaaa aataccgccg gcttctgaca gcgaatgtat tagaattaga
    40441 aatcaatgaa tatgaacttt ttcatagtat ttctttcgat gcatcactga attatttttt
    40501 tcgattcgtt gatccgcaac atctatctct tgcacgcaaa gtaatcgggg aagaattgat
    40561 ccaaaaaaag accaatctaa gtgatagaaa gcttgaacat ttggttttga tgctgacatt
    40621 gacgatggag cgtgtgacga aaaatcattt actgacaaat gagacatata atagtctggc
    40681 aaacaaagaa ttactacaga cagctaaacg attgttttca cggatcgctt ctgagacaaa
    40741 acaactttat ccagtaaatg agatcgtctt ttttgcagga ttattaaatg acttcacgaa
    40801 ctcatttgat cagaatttct ttgaagagac gttcgataca cagcttgctt atttagtaaa
    40861 acaactgatt caagaagtaa gtgaagagac gaatgtccat ttttatgaag atgaaacttt
    40921 gtacaaaatg ctgttgactc atttatctgg tgtgttttca agagccgttt tacaagaaga
    40981 gacactgacc aatccgattt tagaaaaaat catggttcaa tacgaggaag ttgcgaatgc
    41041 aatccgtaaa gcagtagagc ggatttttca agaaaaaaaa ttatccgaag aagagatcgc
    41101 ttatatggtc cttcattttg cgaattcatt ggaacgaagt ccgaaagaaa gcaatatcag
    41161 tattgcagga ttttcgccaa gtggattagc ttctactagc atgttggaac tacgattgaa
    41221 aaggtatttt cccttcatcc aacaaattca tttctatcgg attgctgatt taaaaaaaat
    41281 cgatttacaa gaagaatatg atgttgttat ttctacatct attttaccag gatacggtgg
    41341 aaaatatatt ttagtctccc cgctactgct agaagatgaa gtcaagcagc taaaagaagc
    41401 tttttcgcat attgagaaga aaaaaaggca aaaaattacg tataacagca ataacgagtg
    41461 gatgatagaa gatacttatg aggaaacaat gcatttcatg gatcaaatca atcaattact
    41521 cggtcgtttt tttatccaag aactggataa tcctgagacg atttccgaaa cgattcgcag
    41581 cttatttcct tattttcctg aaggactagt aacggatgaa gaggtggttc atcgccggct
    41641 gcttaagcga tatgaacaag cacctatcgg tattcctcat acaaatatgg ggttattcca
    41701 tacatccagc tcattgattt ctaaaccgat cttttgtatt ttcaatttga aacatccgtt
    41761 gaccattgaa gggatggata gacagccagt cgatttgtcc cgtatgttag ttatgctggc
    41821 gccttcgcca atccaagaaa aagacgggat tcttttagga aagatcagtg gagcaatcat
    41881 catgaatgac ttgaacaccg agatcttccg ctcaggaaat aaagaaatcg tttatcagtt
    41941 gttagcgaaa atcctgattg aagaaataaa gaaatgaagg tgaaaagatg atacagctac
    42001 cagcagaaaa aatattgctc gatcaatcct atcaaaattg gaaagaagcg ttgaccgaga
    42061 tcggccagtg gatgacccaa caagggggaa tcaaaccggc atatatccaa tcaatgatcg
    42121 aaagacaaga aaaagcgagt gtctatatcg ggaatttcgt agccttgcca catgggactg
    42181 acaaagatga agaagtagta gaagaaggaa tctatttagt ccaagtgcct gatggtgtgg
    42241 actttggaac aaaagaggaa ccaaaaatcg cgacactctt atttgtagtg gctttaaaaa
    42301 aagaacatca gttagcggtg ctccaagatt tagccttttt ctgttcagac atcgaccaag
    42361 taatggcgct cagtgatgcg gaaaccattg aagaagtcca aatgattttt gaacatggac
    42421 atatataacc aatgttcaca gtaaaaaaag ctgccttgca tcaagtaata acttcaacca
    42481 agataaaaat aagaggagct atttttgttg ggaggttctt attactgcgg atgcaagctt
    42541 ttgaaaacta tttattctag aaaaccgttt atttgaaata ggggacggtg acaaggtttt
    42601 tgtcaccgcc cctattattt ttgtgtttta atagctcttt tttatataga tagtgcccat
    42661 acctatgaat aataaaacga tactccatat accaagtgtc aagataccat tcatgaaagt
    42721 aacctgttct gaagctagtg gcgagaaaat atctcctcct atgatcacat tttgaaaatc
    42781 aacataagaa gttggcaagt aatgactgat tgattctatc catccaatcg aagaaaacaa
    42841 gcgatactct gctaagaaaa gacaaagaag tgtacctaaa agattgacta gagaatgttc
    42901 aaataaagca gatagaagaa aactgattgt acttaaaaag agcacccaca acaacaggaa
    42961 cagaaagctc tggaaaagat actcatacat cggcaggatt cgtatctcct gaccaatgat
    43021 cgttcctaca ggataacgga agtctcccaa accatttttg attattacta gtatagagac
    43081 gatcaaaaat ggcatcacga gacttagcat agctgcacca taataaatgg taaaacggat
    43141 gctatgtttc tttaccatac tatccggtaa tagattgact agagagatta cctgctttct
    43201 tttttcataa gagatgatgg aagaaagaaa caaggcggtt atacataaaa tcaaaaaact
    43261 agaaatcatt cctgaaaaaa tattttcgta gtaatttgct aaagagagat gcgctggcaa
    43321 gtcaaaaata gaatatcttt ggatctgatg ttctttcata taacggagca actcgacacg
    43381 tttttgttgt tcaatgattg gaattccttg tctttgacca gaaatcagtc gatccagtat
    43441 atctttttca taatgataag ttgcttcgac catttgctgg acattccctg tgttttttgc
    43501 atgtaagatt gcttcgatca gtttgttgct tttctctaaa ctttccacaa attctttctc
    43561 attctcatct tctttcaacg tttcaatcaa acgttgcatc tcttcatagt tatgattcag
    43621 ttcatcgaat tctgtataag caagtttatg atcaaaaaaa agtgggaatg caaagagcac
    43681 gaccaacaat agaggaaata aaaagtttac tttgtttttt agtaagagat tgcgttcaaa
    43741 tgtaagtaaa gacatagtta cacctcatat aatttacgat aaatagctaa aatctcttcc
    43801 atatttgagg attctgtgac gatttctcca ttttttagaa aacatgcttt agaacaaatc
    43861 gattggatat tcgcgatagc gtgggaagaa agaagaatcg tcttcccctc tttctgccat
    43921 tgtctgatga ggctattcaa gatatcaata cttcctgggt ctaatccgtt caacggttca
    43981 tcgaataaca tgacagatga atcactgatc aagtaagcag caagcaagac atgttgtttc
    44041 attcctagag acatttttcc aatcggcaaa gtaaggtact cagtcatctt caatcgttgg
    44101 aaaacagttt ggcattctac tttgctctgc caatagtatt tgatcaaagt caaataatca
    44161 acagccgata gatagtcgga taactgattc gttgattcta gaaaaaagaa agaccggcga
    44221 taatctgtat aagcagtagg agagatgttg tgaagggaca attgatcata agttgttggc
    44281 agcagttggg caatgccatt cagcaaagtt gttttgccaa atccgttcgg ggcaatcaaa
    44341 gcagctactt ctcctgattc tactaaaaga ttcaattgtc gaatcacacg ttttttacca
    44401 cgtttcatgt tcatgttttt gatcagtaat gtcatagata ggcctccaat ataaaattta
    44461 ataacataat agaatggaaa acatctaaat taaatgctaa caaaagttat tgtttgcata
    44521 ttataaaaaa attaaaataa cagttttatt taaaattgaa gttttctgat accgaaatct
    44581 ttttattttg ctgacatact caaacctttg gcacaaagtt tcgtgccaaa gtacgactat
    44641 ttctcttttt agtaagcgga tacaattaga gtatcaaaag gagagaggga gagacaaaat
    44701 ggaacggacg attcccaaaa acaacatttc gctaaaagcg agggtacaaa aattaggcag
    44761 tactttatca agcatggtca tgccaaatat tggagcactg attgcctggg gtgtattaac
    44821 ggctctattt atcccagatg gttatttacc aaatgaggct ttcgctacca tggtaagccc
    44881 aatgctaact tatctgattc ctttattgat cggttatact ggcggaaaag taattgctgg
    44941 tgaccgcgga tcagttgttg gggcaattgc aacgatgggt gtgattgtcg gaacagatat
    45001 tccaatgatg ctaggcgcga tgatcatggg acctcttggt ggatatgcca tcaagaaatt
    45061 tgatcagcta ttccaaaaac ggatcaaatc cggttttgaa atgctagtca ataatttttc
    45121 agcaggtctt atcggttttg gattagcgtt attaggtttt tctgcgattg gtccagttgt
    45181 cgatgcattg actcaagcaa tggcaaaagg tgtagagatc attttatctg cccatttgat
    45241 tccattgaca agtattttta ttgaaccagc aaaaatctta tttttgaata atgcaatcaa
    45301 tcatgggatt ttgacaccat tgggaactga acaagtagca gaggctggaa aatctattct
    45361 attcttgctt gaagcaaatc ctggtccagg acttggcgta ttacttgctt ttactttgtt
    45421 tggcaaagga gcagcaaaat cttcagcacc aggagccatg atcattcact ttttaggcgg
    45481 gatccatgaa atctattttc cttacgttat gatgaaaccg ttattattct tatcagttat
    45541 aggcggagga atgtcaggaa gtttcatttt ccaattgatg gatgctggac taagagcgcc
    45601 agcttctcca gggtcgatca ttgcgattct agcgatgaca ccgttcaatt cttaccttcc
    45661 tgttattttg ggcgtgattg ttgccgcagc tgtttcgttt ggtatttctg cagtaatttt
    45721 gaaagcggat gcgaaagata caaatgaaga cttcgaaaaa tctgttcaag agacaaaggc
    45781 agctaagcaa gcttccaaag gtgcccaagg tattcctcaa ggagctacat tctctggcgt
    45841 acaaaaaatc atttttgctt gtgatgcagg aatgggatca agtgcgatgg gcgcttcgat
    45901 cttgagaaaa aaagtacagg aagcagactt gcctcaaacg gtgaccaatc aagcaatcag
    45961 ccaactgaca gatgactcga atacattgat cgttactcag gtcgaactac aagaaagagc
    46021 aaaacaaaaa gcaccgagcg cgcgttttgt ctcagtagaa aactttttga attcacctcg
    46081 atatgatgaa atcattcaag aattaagcag caagcagaaa acatcagttt ctgaaattga
    46141 gaatgagcca gcagaagagt ttctttcagc aaacatcaaa caaatcaaag agattctact
    46201 tgtccacgat gatcgttccg gatcagcaac aatggggatg accgtgctca aagatatatt
    46261 agacaagaac catttaacta tcccgttaag aaaagtcaat atccaagatt taaaagatga
    46321 acctgattca ctgatcgtag ccaaagaaag tttagcggaa aaagtacaga tggctgcacc
    46381 tcaatccatt catttatcag tcaacagcat ggtcaatccg caaaaatacg aatcgattgc
    46441 acaatatttg aaacagacag cttaagggag gaaaacagca tgcaaagttt gccattcgac
    46501 atgatcgagc tcaatcgatc ttttaaaacc aaagaagaag cgatccgcta ttgcggtcag
    46561 atgcttgtag aagcagggtg cgttgatgag gaatatatcg atgccatggt agatagagac
    46621 aaaatgttat ctgtttatat ggggaatttt atcgcgattc ctcatggaac agatgaagca
    46681 aaaaaatatg tgaaaaaatc cggcatctgt gtcgttcaag taccagatgg tgtagatttt
    46741 ggtaccgaag aagaagaaaa gattgcgact gttttgttcg gtattgcagg agtcggagat
    46801 gagcatttgc aacttgtaca gcaaatcgca ctttattgca gtgatatgga caatgttgtc
    46861 cagctagcag acgcgctcag caaagaagaa gtaacggaaa atctagcaat tgcttaagga
    46921 gagagaaaaa tgagagcagt acattttggt gcaggaaata tcggtcgagg atttattgga
    46981 gaggttttgg cagctaatgg atttgagatt actttcgtag atgtgaatca cacgatcatt
    47041 gatgctttaa atgaaagaaa agaatacgaa atcgaattag cagatgaatc aaaagaaaaa
    47101 atcactgtaa aaaatgtcaa aggaatcaac aatcaaacaa atccagaaaa agtaatccaa
    47161 gaaatcgctg aagcagattt agttactacc gccattggcc cgaatatctt accttttatt
    47221 gctgagttga ttgcaaaagg tatccaagaa agagaaaagg aaggaagcac aacatcttta
    47281 gatatcattg cctgtgaaaa tatgattggc ggttcagcat ttctagaaaa agaagtgtat
    47341 aaatatcttc cggaaacatc atttactgac aaatatatcg gctttccaaa tgcagcagtc
    47401 gatcgaatcg tcccattaca acaccatgaa gatcctttat tcgtccaagt ggaacctttc
    47461 aaagaatggg tcattgacga tagccaaaga aaaaataaaa aaatccaatt aaaaggggtt
    47521 ttatatgtag atgatctaga accatatatc gaacgcaaac tatttagtgt caatactggt
    47581 catgcgactg tcgcttatac aggtgccttg ttaggttacc agaccattga tgaagcaatg
    47641 caagatgcgt tagttgtggc acaattaaaa tcagttttgc aggaaacagg aagtttgctg
    47701 attgccaaat gggggtttga tgcagagcag catcatgcgt atattgaaaa aatcattcat
    47761 cgcttccaaa acaaaaatat ctctgatgcg atcacacgtg tcgctcggac accattacgt
    47821 aagttaggtt atcaagaaag atttacacgt ccagtgagag aactacaaga acataacttg
    47881 acttgcccac atttgacggc aacaatgggg attattttta attactatga tcctgaagat
    47941 gaacaaagcc gtcaattgca tgaaatgaag atccatgaaa acttggaaca attgattcaa
    48001 gaagtcacag gaatcaatga tccgaaaaca atcgggaata tcaagcaaaa cgtgaaccgt
    48061 tatgccaagc aagtcgctta aaataggata cgaaaaaggg gaatgtgacg aaatttttgt
    48121 cacattcccc tttttcgaat aactaggctg tttgtccttc aagatagggc agatccaatt
    48181 ctttaccgta acgttgttct aaagctaggc ggatcaaacg agctgccagg ttctcatttc
    48241 ttgcaaggat aggtccatgg aaataagaac cgaagacatt tcggtaaatg acaccttcag
    48301 attggtcttc accattattt ccttgacctt gtaccacttt ccccaaaggt cgttcacctt
    48361 cacctaagaa agtccgacca ttgtggtttt caaatccata ataagtttca ttgaattctt
    48421 cgttatggat aacgatatca ccgataaacc ggttattttc ctgacttaac gtgtagtgat
    48481 ccagtgcact gattccttgg atcttttctc cattagctcc catgtagtag tgacctagca
    48541 attggtagcc accacaaatg gctaacatga cgccatcatt ttcgatatag ttgatcaaag
    48601 aatctttctt tttctggatg tcttttgaaa tgattaattg ctcaaagtct tgaccaccgc
    48661 caaagaaaac caagtcatat ttatcagcat caaaaggttc atgtatacta acgatctccg
    48721 tatggcaaga aacccccatt ttttctgcta tatatttcaa catcaaaagg tttccgttat
    48781 caccatatgt gttcatcaaa tttccataaa ggtgggcgat attgagttca taattagcca
    48841 cggttcattc ctcctttgat aaatccttga gcagctagtt ctttacgaag ctgcaataca
    48901 gcagtgtaag tagctaaaat atagacatgc tcagttggca attctttgat tttttcgatt
    48961 acttctggta attcttttgt ttctgtcaat ttattttctg gaatcccggc aacttttaga
    49021 cgtaaagtca tatctgtatg acggtctcct ccagaaataa cagctgggat atccatatcg
    49081 gcaaagtttt caaaattacc atcccaaatc cagctgacat cgattccgtc tgcgtaattg
    49141 gcatttaata aagccactaa agaaaatgga taaggagcta gaccaatcat atcgattact
    49201 tgattgatac ctacaggatt tttgacaagt actaatgtac attttttccc attgatattg
    49261 atgacttctt gtcggccgaa tactttctcg tcatatccta aaccttgttt gattttatca
    49321 ggatcgacat tgaagtactc tgccactgca gtagctgcta aagcattgta gacattatac
    49381 ataccgccaa cttcgattcc gtattcatga ccatcgatca cgaaatctgc tgacacattg
    49441 tccatccgta ccatatcagt taatcgataa tccaattcag gacgtttgaa gtcacaattt
    49501 ggacagtaat atttccctaa gtttgcataa gtgatcattt tataatgcaa gatgtgatga
    49561 caatttggac ataagacacc gtctgtattg taatgagcca tttgttcacg atcttcttca
    49621 tggtcaaagc cataatattt tctaggattg actgtttcga tagaattgaa gattggtgaa
    49681 tcaccgttac tgataatcgt tgcatttggt gactttgcgg caccgtctac aatcatttta
    49741 taggtcgtat agatttctcc ataccgatcc atttgatcac ggaaaatatt tgtaaataag
    49801 aacagttctg gtttcatata ttctgtgact ttgctcaaac ttgcttcatc tatttctagg
    49861 acagcaaact ttttctgtcc tttttttggt tttgcctgca agaaagtcga tacaattccc
    49921 tgtaccatat tcgcaccagt agggttggtt agaacttcat cgaattgctg gcgcaaaata
    49981 ttgactgtta aagcggtagt caatgtttta ccgtttgttc cggtgacaac gacgacttgg
    50041 tagtcttttg ccaaactatc tagtatatgt ggatcgactt tcagcgctag tttacctggt
    50101 aaacttgatc cgcctttaaa aaaagttttt aatgcccatt gcgacgtttt tccaactgca
    50161 atcgcaaaat gactgcgtat tcccattatg taacctccaa aaacgatttg ctgacgaata
    50221 aattcaacta atcataccat atgttgaaaa aaaggttaaa ttgcttttct tattcttaag
    50281 aaaaggttac ggctgaaagt gcatgaaatc ggacaaaatc gcatgattta acaaaaaaac
    50341 agcttgaaac aaaatgattg tttcaagctg ctgtgatttt attattccct cttacctata
    50401 ttcccatttt aaccgataat aattttctcg cttggatatt catagcctag atctcgtgtt
    50461 tcttttggca cgaataacat caatgtatat agcattccga tccgcccaat aaacatcagt
    50521 gtagcaatcg tgattttgcc cacaacagac aagtctccgg taatccctaa agataaacca
    50581 gttgttccaa acgcagaagt tacttcgatg atgatcgaga tcagcgtttg ttcttctgta
    50641 gcagataaaa aaacgataca aaagaaacac ataccaagag aaagcataaa gacaacgact
    50701 gattttcgca catcatcttg atcgattctc cgtccaaaaa tattgatgtt atcttcactt
    50761 ttgaggaagg aatatagata caaaccgatg attgctacag tagttgttcg aatcccgccg
    50821 cctacagaac taggactgca tccgataaac atcagtaaag aaaaaatgat cagtgttgtg
    50881 atttgaaaat cacccaaatc gtgaatctgc agaccagcat tacgagtcgt aatcgaataa
    50941 aacatcgaat tgatccattt gacactcata ttggaatctt ggaataaatg gtccttttcc
    51001 aatagataaa tcaagacagt tcccgaaaca aacaagataa caaaagctaa cacagctaat
    51061 ttggtaaaca aggaaaaacg aaacggaagc ttcgcattgg aacgtttgta taatagccat
    51121 tcccggcact ccatcaatac aggaaaacca attcctccga caaaaatcaa aaacatgatc
    51181 aggatcaaga aaaaatagtc atgtgcaaag ggcttgatgg aatccccagt gacgtcaaac
    51241 ccagagttcg tgacagccga tatcgcctga taaaaaccgt aaaaaacggc atcacgccaa
    51301 cgatcaaaat agcctctgta ataaaaataa atagaaaaga atgtcccaaa aagtaattga
    51361 aaccagatta aaatagcaaa agtgatccga atcagtcgga cgataccaga caaacgcggt
    51421 tgattcatat ccgtcatgat cagctgtcgc tgtttcagtg tgatccgtcg tttagaaaaa
    51481 atgacaaaag cagtagaaat catcatgatc cccaaaccac caacttgaaa taatatttcc
    51541 agcagtataa taccgttatc attgaacaca gaattgatat caaaagtcga tagtccagtc
    51601 acactcactg tactgattgc catgaacagc atgtccacaa aagaaacatg gctatctggt
    51661 tcgcgaaaaa tcggcatata aaatagaacg agtgataaga ccgtcatcaa tatataataa
    51721 aaaacgatga tttggatcga tgagaaatga ttggcagcaa acttctgtcc tcgccgctgc
    51781 agccttcgaa agaataaatc aacatgcaca gtactatcct cctgacaata gtcgtttcta
    51841 ccagtataca aggggaatta ggaatactca aagaaattat caaacagata acaatacagc
    51901 tttcgattaa aatagaaatg gcttataata aggaaaatcc tagaaaaaag aaggaggagg
    51961 aataacaaat tgattaatgc tcaacaaatc gtagaaaaaa tgaaaaatca aaaaataaat
    52021 tatgatacag ttctgaaaaa aatgatcatg caatgggaga aagaagaagt aaagcctaag
    52081 atattaatac atacatgctg tgctccttgc agtacgcaca cattggaatt catgtctcaa
    52141 tatgcagaga tcacgttatt tttttcaaat tcgaatattc atcctaaaag tgagtatttg
    52201 cgaagattac atgaacaaaa acgatttgta gaccaattta atgagaaaac tgaccatcat
    52261 gttgcgctaa tcgttgatga ataccgtcca aatgaattca ccaaaatggt tttaacaaac
    52321 catcttgaaa acgaaaaaga aggtggtgct cgctgcagtg catgcttcaa tatgcgatta
    52381 gatcttgttg cgcaaaaagc gcaagaacta ggatacgatt actttggaag tgccctgacc
    52441 atctcgccaa agaaaaatgc agctttgatc aatcagatcg gaatggatat ccaaaagatt
    52501 tacgggacac aatacttgcc aagtgatttc aagaaaaaca aaggctatga acgctctttg
    52561 caaatgtgca aagagtatga tatttatcgc caatgttatt gtggttgcgt gttcgctgcc
    52621 aagcagcaag gatgcgatct gaaagaaatc aatcgggaag caaaagctta cttaaaaaca
    52681 tcaaccgtag tttttgagga aaattaaaga aatctttcgg aaaaacgtaa gaaaaaaata
    52741 aagaatttat ggtagaaata aggtagactg tataatttgt ccgtagtaaa gtaaggaaac
    52801 aagaataaat ttcaatgaag gaagagataa gatgcgaaaa gtagcaccta ttttgaagcc
    52861 aatcgctgta ttaacaatct cgacgattgt cgcgactact acaggtattg tgaatagttc
    52921 cagctaccgt gcaccaagtt caagttctag tactgtagaa gaaacaacac caactacttc
    52981 agtctcgaca tctgaaccaa caacaacgga aagtttgaat gaaaccacta cgacaagtac
    53041 atgggacgat acaacaacta gttcgtcgta tgatgagaca tatacaactg acagctcaag
    53101 cgaaacaagt aatacggtac cagatggcac tccatcggat tcaaccaatc caagtacaag
    53161 tccggataca agtgctagct ccgaaacgat accaagcagt acgactgtag atgataacac
    53221 gcaaaatgat gatgcagcac gtacagcaca gcaaaaccaa gattcaggaa atacccaaac
    53281 gtataaccag caagcaggtg attctcaatg acatttttac tagaccttat caacggggtg
    53341 cataaattcc ttggctattt agacatcagt cctaaatatc ttaaccgtgg atatacgatt
    53401 ttaagtgtga ttcccacgct ttatttattg agaattgttt atggactttg gcaaaaccaa
    53461 aactatcttc aatttttctt atatggactt gcatttctag tgcttgttta ttttactgtt
    53521 ttaaatgtat tttattactt tttagataaa aacacgaaag ccgatgtcac tcagcttttt
    53581 gtgaagtatt tacctgatga agcgttcaac atccagacag aagaatcgat agataatgga
    53641 aattcgatcg ataaagtgaa tacacaagag gtcatggttt cttatgacga agattatcaa
    53701 ttgaaattag ccgagaatat gcggtatttg attggaaatg gtgagatcaa aacaaatgaa
    53761 ctcggtcgca tggatggatt tctggtcgat agaaatacat tgtatcctta ttactatgtc
    53821 aagaaaacag gagagaaaga gtatgttcta aatattggac gaagctactc ggacatggaa
    53881 aaagtaggga ccattcgact tgactcaaca gaagacacat tggaacctgt cggattgttc
    53941 atcgtcggcg gtgattttgt caaagacggg ttacgctatc atgagcctta tcgtctgaaa
    54001 ttgattgcaa aaaaggcaca gtcgcaggaa gaactagtgg tttatagtcg tagccaaaga
    54061 agaagacatt cataatgtga tgaaacgccg tgtatcagtg gttgcgataa aaacgtttat
    54121 tcggaataag ggggatgtga cacgtctttt gtcacgttcc ttttttatat aacgagaaag
    54181 ataagacgaa cacatcactt attctttcct ttcatttata aacattgtag aataaagaaa
    54241 gtacaacgaa gtattgtgaa aaaacgtaat aaataacgag gaaaatacaa gtaggaggta
    54301 agctgtgaaa gaatttttga aaaattgggg gattttgatc cttgtattag cggctatttt
    54361 attagctaga gtgtacgtgt ttacaccagt tactgtaaac gggcattcga tggaccctac
    54421 attaagtgat ggacaacgat tgatttcatc taagatctca aactatgaac gaatggatat
    54481 tattactaca aaggaaccgg gggatgaaga acggatgatt gttaaacgga tcatcggtat
    54541 gcctggagat acagtcaaga tggaaaatga ccagttgacc attaatggca aaaagtatga
    54601 tgaaccttat ctggatgagt tcaaaaaaga attttcagaa gataagttac aaggagaata
    54661 tgcttatagc tcaggattcc aagcacaagc agaaagttca tccaccttta cgagtgactt
    54721 tgaatatact gtgccaaaag gaaagtatct tgttctaggc gataaccgct tgatttcaaa
    54781 agacagccga atgtttgggt tagtcgacaa agatatgatc caaggaaaag ttgttttccg
    54841 ttattggcct ctttcagaaa ttaaaatcat gtgatgaaaa aataaaaaga agctgtgaca
    54901 tgttttttgt cacagcttct ttttccgaaa attccttctt atttcttgga gttgctcact
    54961 ttttttgcaa tctcatttta agctttttgg ctgatggata agaaaagcga agcgtttttg
    55021 ttcataaata gcttttcccc acgatggaag gtatgactag tagcagagac aaagcccgtt
    55081 ttttccaatc gattattcaa ttcttcttgg ctaaagccat tatggacttt cggatgacta
    55141 atttgttcat tcttgtcaaa gtctacgatg atcaattgac cgccaggagc taaaatttca
    55201 taaagttttg taagaatatt ctccgtatca ggaatgtgta aaagtacaag tgatagaagg
    55261 atgagattag cttggacagc aggaaattcg acagaagcat cagcgtggat cgttcggaca
    55321 tttttcagat ctgctgcttg gatcttttct tctgccattt tcagcatagt ttctgaagca
    55381 tcggcaatga tcagttcttt gaatctttcc gcaagcggta aactaacaag cccagttccg
    55441 cctccgtaat ccagcaggac tttttggtgg ctgtcgcgcg gtagataagt agttagttct
    55501 tcgcgaataa tcttggctaa tgcttgacgg tcaggggaat cataatggtt agcgatggaa
    55561 tcaaaaatat tttttgtcat caaatagctc cttacgtaaa actttgaaat tttaacttat
    55621 tatagcacgt gaaaagaaag aaagcatgct atactcaatt caaaaaggga gaatctagaa
    55681 agaatatgcc gatatcgttt gtaaaagata gagaggaaaa aggaaagtgt gtccgagaaa
    55741 tattactaga cttgcctgag tggtttgggc ttcctgaatc aacggaaaaa tatatcgagg
    55801 aatcaagtaa actaccttta tggtgtgaaa aaagaaaaga agaatattta ggctttatca
    55861 ctctttcaca gacaagtgaa gatactgccg aaatctattc tattgtatgg gaataaaaaa
    55921 agactatcat caccaaggat taggaacaaa actttttaaa gaagcagaag gttacgcagc
    55981 aaaacattac aaatatttgc aagtgaagac tgtagacgag gggcactact ctatatatga
    56041 tcaaactatt tgtttctacg aatcattagg attttcaagg ttggaagttt ttccaaattt
    56101 atgggatgaa tggaacccat gtttagttct tgtcaaaaaa ttggaacaaa agtgagcaat
    56161 agatttaata ctaatctgtg cttgatgaaa attctcactg taaaaaatgc tgaaaatcaa
    56221 gtataatacc ataggaacaa actggaaggt gaaaaagagc atggcacaac tattttttaa
    56281 gtatggcgca atgaatagcg gcaagacgat cgagatccta aaagtcgcac ataattatga
    56341 agaacaaaat aagccagttg tcttaatgac aagcggtatt gatacaagag atggtttagg
    56401 cgttgtttca agccgaatcg gactgaaacg taatgcgatg ccgatatttg aagaaacaga
    56461 cgtatttgac gtaattcaga aaatggaaag caaaccctat tgtgtgctga tcgatgaagc
    56521 gcaattctta aaaaagaaac atgtcattgc ttttacgaga attgtggacg aattggatat
    56581 tccggttatg gcatttggtt tgaaaaatga ttttcgaaac gagttatttg aaggatcaaa
    56641 atatttattg ctttatgcag acaaaatcga agaaatgaaa acaatctgtt ggttctgcca
    56701 caaaaaagca atcatgaatt tacattatat tgatggaaac cctgtttatg aaggcgatca
    56761 agtgcaaatt ggcggaaatg aagcttatta ccccgtttgt cgaaaacatt actttcaccc
    56821 atcaatgatt acagaaggag aataagcatg tacgatcaat tacaagcaat tgaagaccgt
    56881 tatgaagagc ttggagaact tttaagtgac ccagaagtga tttctgatac aaagcgtttt
    56941 atgcagcttt caaaagaaga agcaaacacg cgcgaaacag tcgaagttta tcgtcgttat
    57001 aaagaagtag tacaaggaat caccgataca gaagaactgc ttggtgaaaa actggatgat
    57061 gaaatggctg aactagcaaa agaagaatta tctgaattaa aaaaagaaaa agaagtctta
    57121 gaagaaaaaa tcaagatctt gcttttacca aaagatccaa atgacgataa aaatatcatc
    57181 atggaaatcc gtggagcagc aggcggagac gaagcagcat tattcgctgg cgatcttttc
    57241 aatatgtacc aaaagtatgc tgaagcacaa ggctggaaaa cagaagtgat ggaagctaac
    57301 gttaccggaa tcggtggata taaagaagtg atcatgatga tcaccggaga caacgtatat
    57361 tcgaaattaa aatatgaaag tggtgcgcac cgcgtccagc gtgttccttc aactgaatcg
    57421 caagggcgta tccatacttc caccgcaaca gttgtcgtga tgccagaagc tgaagaagta
    57481 gagatcgata ttgaagacaa agatatccgt acagatatct atcatgcttc aggtgctggc
    57541 ggacagcacg tcaataaaac agcatctgct gtacgtttga ctcacttacc aacagggatc
    57601 gttgttgcta tgcaagatga acgttctcaa atcaagaacc gtgaaaaagc aatgaaaatc
    57661 ttgcgtgctc gtgtgtacga taagatccag caagaagcac aaagcgagta tgatgccaat
    57721 cgaaaatcag cagtcggaac tggggatcgt tcagaacgga tccggacgta taatttcccg
    57781 caaaatcgtg tgactgatca tcgtatcgga ttaactatcc aaaaattaga tcagatttta
    57841 gcagggaaat tagatgagat cgttgatgca ttgatcatgt atgatcaaac atcaaaactg
    57901 gaagctatgc aaaatgggta aaatgaccta tcgagaagtc ctgtcacggg cttcttcttt
    57961 tttagaggat catgggaaag aagcatatag tatccaattt ttatttttgg aacgaaaaca
    58021 atggaaaaaa cttgattggc tccttcatat gaacgaagag atttcagaag aagaacagcg
    58081 gttgatcgaa accgatctgc gacttctgct tgcagatcat ccacctcagt atttgctagg
    58141 atatgcagat ttttatgatc atcggttaaa ggtaactgaa gcaacactga tccctcgacc
    58201 agaaacagag gagttagtcg aatggtgttt agacgagacg cctggtgtac cgttagaagt
    58261 gatagatatt gggacaggga ctggagcaat tgctattagt ttgaaagcag caagaaaaaa
    58321 ttggcatata tctgctgtgg atctttcaga agaagcatta gaagtagcga aagaaaatgc
    58381 tcagaaagaa ggaacgaaaa tcagttttta tcatggagat acattaggac cagtaatgga
    58441 tcagcaattt gatgtgatta tttctaatcc gccgtacatc agtcggaatg aatgggaact
    58501 gatggatgaa agtgtccggt cattcgaacc taaaatggcc ctttttgctg agaacgatgg
    58561 attagctatt tatgaaaaaa tagcagttga agcaccaagc gtactaaaat caaatggaaa
    58621 gattttttta gaaatcggat ttcgccaagg tgaagcagta aaaaaaatat ttcagcaagc
    58681 atttccagat aaaaaagtgg cgataaaaaa ggatcttttt ggcaatgaac gaatgatcca
    58741 agtttatggt tgaagttgtg gatgaaaaat tttttatttg tttttttatt ataaaaaaac
    58801 acttatttga caaggatgta aacgactttt tggtttatca acaagtttat ccactattga
    58861 caaatagatt atccacaaac agtggaaaac ttgaggataa actcagacaa aataagaatg
    58921 tatgaaaaag gggttgtgga taaactgtgg aaacgaaacg atatgatgaa acagaattgc
    58981 aagaggcagc cgaagcactg aaagaaggag aacttgttgc ttttcctacc gaaacagtat
    59041 acggattggg cgccaacgct cttttaccaa acgctgtcaa gaaagtgttt tctgtaaaag
    59101 ggagaccgca agataatcca ttaatcgtcc atgtcgcctc ttttgaacaa gtaaaagagt
    59161 atgtggacaa ctttcatccg gcagcagaga agattgtgaa gaacttctgg cctggaccat
    59221 taactttgat atttaagatc aaaaaagaca ctttgccctc agttgtgacg ggaggattat
    59281 ccacagctgc atttcgtata ccggataaca aaaaaacact agaagtaatc gaactttccg
    59341 gtgttccgct tgtcggtcca agtgcaaata cgtcgggaaa accaagtcca acgactgcag
    59401 atcatgtata tcatgatcta caaggaaaaa ttaccgggat tattgatgat ggagctacgc
    59461 gaattggtgt agaatccact gttcttgatt taagtgatcc aacagccatg cctatgattt
    59521 tacgaccagg tgcagtaacg aaagaacaaa tcgaagcagt catcgaatct cctgttgcta
    59581 ttgatcagca tcttgtaaaa gaaaatgaaa caccaaaagc ccctgggatg aaatacaaac
    59641 actactcacc cgatacacgt gttctgatgg tcagagatgg cgattggtca actgcagttc
    59701 aatgggcaaa aaataagaag atccgtgcag gtgtcatagc aagccccgaa attgcggatc
    59761 aagtgcggac agatactgca gctgtttata tgtataacga caactcagta gaagcggcgg
    59821 ctaaaggatt gtttgcaggt ctaagaggat tagatgaacc aacacttgga ttagatttga
    59881 tttttgtaca agtgtatcca gaaactggat tggggaatgc ttacatgaat cgcttgaaaa
    59941 aagcagcagg acaaaattat tttgaaaaat gatcaattgg ttattgtcgc attcttttag
    60001 tatgatacaa tgctatcaag taaatcttct atcagtgaac gaaaaactaa gcgtaactaa
    60061 tcgtaataga agagatacga atatttggca atttgttttt gatgggaaaa ataaaattgt
    60121 aggaaaataa aaaggagctg ttgtttgtgg tagattacaa aacgtttgac cctgatcttt
    60181 gggctgcgat cgccaaagaa gaagaaagac aagaacataa tttggagctg attgcctctg
    60241 aaaactttgt ctccgaagca gtgatggctg cacaaggaag tatcttgaca aataaatacg
    60301 cagaaggtta tccagggcat cgctattatg gtgggtgtga atttgtcgat atcgttgaaa
    60361 atttagcgat tgaccgtgca aaagaattat tcggagcgaa atttgcgaac gtccagcctc
    60421 actccggctc tcaagccaac acggctgctt atctcgcttt ggtagaacca ggggacacga
    60481 tcttaggaat ggatctttcc gcaggcggac atctaacaca tggatcacca gtcaacttca
    60541 gtggcaaaac ctatcacttt gttgcttacg gtgttgatcc gacaacagaa gttattgatt
    60601 ataatgtggt acgtatttta gctagaaaac atcaaccaaa attgatcgta gcaggtgcca
    60661 gtgcttacgg acgaacgatc gactttgcga aattcagaga aatcgcagat gaagtaggcg
    60721 caaaactgat ggtagatatg gcacatatcg caggattagt agcagcagga cttcatccta
    60781 atccagttcc ttatgcagat atcacaacga ctaccactca taaaacattg cgtggccctc
    60841 gaggcggcat gattttgaca aacgatgaag cattagcaaa aaaaataaat agtgcggtat
    60901 ttcctggtat tcaaggcggc cctctagagc atgtgattgc gggtaaagca gtagcattca
    60961 aagaagcatt agatcctgca tttaaagaat atagtgaaca aatcatcgcc aatgcaaaag
    61021 caatggtcaa agttttcaat caagcaattg gaaccagagt catttcaggg gcgacagata
    61081 atcatctgat gttgatcgat gttcgcgagt taggtataaa tggaaaagaa gcagagagca
    61141 ttttggacag tgtgaatatc actgtaaata aaaactcgat tccttttgaa acactaagtc
    61201 cattcaaaac aagcggtatt cgaatcggca cgccagcaat cactactcgc gggttcaaag
    61261 aagaagatgc tgtaaaagtg gctgaactag ttgtcaaagc attacaagca aaagatgata
    61321 acgctcaact agacgaagtc aaaacaggtg tacgcgaatt aactgaaaaa tttccgttgc
    61381 ataaaaaata aaaatttaaa ttccattagt aaacagaaaa gttcaatgtt gggcttttct
    61441 gtttattttt tgggaaaacg gattctttga caatatcggt gatgctctct agtatatgag
    61501 gtgtaatttt agtcttcaca ctaaatctca gggaggaaaa gtcatgactg atcgtatctc
    61561 gttagaaaag gaagcagtag cattcagtga tgcaaatgcg cctcatccgc gtatctatga
    61621 actagcaccg gaagaaggaa gagttttact agaagaagta caagaatcac ctgtgaacaa
    61681 atattccgtc gatattgaag acttgatggt ggatactggc gaatggggaa aactcaatat
    61741 tcgtctcgta cgaccagaag ggaatatgga taaattacca gttatttttt atattcatgg
    61801 agcaggctgg gtttttggca gtgctcaaac ccatgataaa ttgatcagag aacttgcggt
    61861 tcgtacgaat tccgtcgttg tctttccaga atatagtcga tcaccagaag caaaatatcc
    61921 aacagcaatt gaacaaaatt atgctgtgtt gcaacagctg aataaattag ccaagtcaaa
    61981 aaatctggat ctcgagaatc taatcgttgc aggagattca gtaggtggta acatggctac
    62041 agtcatgacg atcttaacaa aagaacgaaa gggcctccca atatccaagc aattgctgta
    62101 ttatccagtc acaaacgctg attttgatac agattcctat catgaattcg gagaaaacta
    62161 ttttttgaca agagaaggaa tgatgtggtt ttgggaccaa tatacgacga atgaagaaga
    62221 gcgtgctgaa atcacagctt cgcctttgag agcaaatata aatgaactaa atgatcttcc
    62281 ttcagcaatg attttaacgg gagaagcgga tgtattaaga gatgaaggtg aggcttatgc
    62341 gcgcaaactt cgtgatgcag gggttcctgt tacacaagta cgcttccaag gaatcatcca
    62401 tgattttgtc atggtaaatg ctatggatca gacaaaggca acgcgtgcag caatggcatt
    62461 atctacttct tggatcaaga aaaaagaata agctttgctt gtccgcagga aaacttcttt
    62521 tcaaaaacgg attttcttag gaaaaatggc gagtttgact agtcaatcac ttgattttgt
    62581 tttacaatta aaaagaaacg acagaacaaa ggagagctta aaaaatgggc aaatttcaag
    62641 tgatcgatca tccattgatt caacacaaac taactattat tcgggacaaa aactgcggaa
    62701 caaaggtttt tcgtgaagta gtcgatgaaa tcgctatgtt gatggcatat gaagtatcac
    62761 gggatatgcc attggaagac atcgtgatcg aaacaccgat cactgaaaca acacaaaaaa
    62821 cgttgtctgg taaaaaagta gcgattattc caatcttgcg cgcaggtatt ggaatggttg
    62881 acggtatctt ggaattgatt ccagctgcta aagtgggaca tatcggtctt tatcgagatg
    62941 aagaaacatt ggaaccacat gaatatttcg tcaaacttcc agaagacatt gatgcacgtc
    63001 agttgtttgt agtagatcca atgttggcaa caggcggatc agcaatcatg gcaatcgatg
    63061 cattgaaaga acgtggcgcg tcgaacatta aatttgtttg tttggtagca gcacctgagg
    63121 gagtaaaagc tttgcaagaa gcgcatcctg atattgacat ctatacagct tctctagatg
    63181 aaaaattgaa tgaacatggt tatatcgttc ctggactagg ggatgcgggt gaccgtttgt
    63241 ttggtacaaa ataagtaaat acgaaaaagg gtgtgacaca acttttgtca catccttttt
    63301 tggtcatttt taacgtttga tgcagaacag ctttttcaca gctttcgttt gcatataaaa
    63361 aaaccatccc aaaaatgcag agatggtcaa attcaaatct tttttagttc tttgtagtta
    63421 acgattacta cacccttact ttgcgtcatc aagttcgcat tttctgcagt ttcatcaatc
    63481 tcaacaacag cggaattttt caattgcttt gaaatcgttc cagtttgcga cttgccgtga
    63541 attgtgaaca ttacgtgagt attgatcttg aatttttcac caatttccga tggtacgata
    63601 gttgtatcaa attttccaaa agttgccatt ttcataaaac ctgcctttca catcaattat
    63661 accacgtttt atgaaaaata tcatgaaatt aaactaattt tccatcggac tctttacaat
    63721 cagccaaata gagtatataa tttcttttgg ataaggccag cttagctcag ttggtagagc
    63781 aacgcactcg taacgcgtag gtcgtaggtt cgatccctat agctggcatt aaaagagaag
    63841 acagatatat caaggatttt taatccattg atacatctgt ctttttgttt aaaggaaata
    63901 aagtatgctt tcttagcaat agagcatgta ttatttctat aaaaatttag gagaataaaa
    63961 cgactagcaa tatagctgtg aaatcaaata tcacatgaac tgcccaactt gtaatgatcg
    64021 agttgctttt aatggcagct tggttgaata acaatcttgc caccccttgt atcaaaagga
    64081 tgtgtgctac agtgtgtaaa atatttccat tatcataagt actgtaatgg ataaatccaa
    64141 agatgattgc tgacaagaaa ctagcgacag gaatgctgaa cttactagaa aaaatagcga
    64201 gaaaatacac tgagaacaat tcttctccaa gtatcatgat aggcaaaata ataaataata
    64261 acgggctgaa agcctcattt attggattgc ctgttaaacc ccatttcaaa atttgttgca
    64321 aaaataccga gactgcggca ctgattacta cattgataaa aaaatatttg gctatatttt
    64381 tgacaggagc gacaggtttc gagaacattt ttttcgtatc ttttttacca aaaacaagtg
    64441 taaatgctat aaatccagtg atagttaaag aaaaaatgct aataatggat ggcgcaaata
    64501 gcaaccctaa caaaccgagt acaacgacaa tagtgcccaa tatccctttt ttaagttcta
    64561 ttttttttcc taaaatgtta ttcatgataa taactcctac tattcagttt ttgaagatag
    64621 agtcagtata catgaagagt taaaataggc aatgtttttt tatggatatt tgtattgcta
    64681 aaaatttatc ttatatattc attttgatta tactactttt atttgtaaaa attttctagc
    64741 aaaaccaagt gcttgcaact gattaagcgt acaatttttt agatgttccg agcgtacttc
    64801 aatcatttca aaggagttgc tacttaaatc gatatttttt aaatcagtat caaaaaagct
    64861 agcattttct aaatcattag tagaaaacat tattttagtg agggaacagt ctacaaaatc
    64921 tgcgcttgat aagacagagt gctcaaaggt actttctttt atgtttgaac cagataaatt
    64981 tacatagtcc attttacaat tctcgaataa cgtgttccca atataacttt ccatcaattt
    65041 agtacctgtt aatttacaat tgacaaattt cacgcgatgc aacatgcttt ttgtcaatat
    65101 acagcctgaa aaatcacagt tttcgaatat acagtcggta atctccattc tttgaaaatc
    65161 attggaagca aaaaatgcat acttgaaaat agatttgtaa ataattggat ggcagattat
    65221 ttggttttcg atgacctctt tttgtgaaag gatattatac agttcaaaat cttcgttttc
    65281 atagatatga aaaaaggatc ctttattcaa gcttgcttca ttaactttag gaaaaatcat
    65341 atttaattac ctccattttc ataaagtcat attaacaaaa gctaaaccaa cttacattag
    65401 cagaaaatga gataggtttt cgcctttttc gataacgata gtgtcgctat ctcttgaaac
    65461 gttcttagaa ttgccctgag agacacaaat taggcgtaat tctaataaaa atcttagaat
    65521 aaaaattttt actgatttaa tttagaatgt ttttaaaata aaaatcgttg ccataacagt
    65581 gtattgaaag gttttaacaa tccagtaatg atttaaaaaa atctagatgt agcgtatact
    65641 ttgtttatag aatgtagtgg gaagaaatat atttttggga ggaaatcgtg atgtctaaaa
    65701 gtgaagaaat agaaaacatg gtactaaaat tatatgatct cgttttaaat ccagagatca
    65761 aagaaaagga acgtatactt ttgatagacg caaagacagg cttagaaaaa ggtcagtatt
    65821 atcctaaagt cataaataat ttggaacgta gtttacgtcc gttagcaatc aggggagaat
    65881 tgtctaaacc agtatcaccg ttttatatgg agatatcaac aataggaaaa tttgaaaaag
    65941 aattaggtcg aggaatggct tcggcaccga ttacttttgg gcatttataa aaacgagtta
    66001 ttcatctcaa tgaattaaaa agtatagtca atctcataat gcaggctagg ttcatttatt
    66061 tgaacagagt ctgtattttt ttattctaaa taaagaaaca gatgtttctt tatattgtat
    66121 tttatccttt aattaacaca aaaacagcta gtataaacta ataatgttaa ttaaaagtgt
    66181 attttatgaa actatcgtta tttattaatg ttgcattttt gtaagttaaa aattggaaat
    66241 atagattgaa aaaatgaaag caataagtaa aataaaatga atatatgcga aaaaataatt
    66301 tacattagga aaaaccttgt aaaaacagtt ttttggcata tttatttttt ataaatattt
    66361 gtaaaataac tatcaatttt ttagttaaaa gattggaaat gagtggggga ggaattgaag
    66421 aaaggatttt tgagagatga tatagtaggt tttattttta gttaaaatag gggagataga
    66481 aaaaatgaaa aagtgtagaa atattatttt atcaatgtta tttattatta ctaatataac
    66541 atcactgatt cctgttcatg tctatgcgga tgcaggcaga gatatcagca gtaatgtcac
    66601 ttcgttgacc gtggacccaa cgaatattac agatggagga aacataaaag taaaattctc
    66661 gtttgacgaa aaaaaacaaa atatccaacc aggtgattat ctttggatca attggccaag
    66721 tgaaggaaat attcgcggtg aaggattcca aaaagaaatc ccattaatga ttgaaaataa
    66781 aaatgttgga actttaacgg tcagaaaaga ttctgcgcag gttgtgttta atgaaaatat
    66841 taaaaaccta gactcagtag aaggttgggg gcaatttgag atacaggcca gaaacgtaac
    66901 cgataccggt gaagaaaata cgggaccatt caccgtgacg agcggtgata aaacagctac
    66961 tgtaaatgtg acaaagccag cttctggttc ttcttctagc gttttttatt ataaaacagg
    67021 agacatgcta cctgaagata ctaagcacat tcgatggttt ttgaatatta acaataacgg
    67081 cacttatgtt gaacaaccag ttaaaatcag tgatgaaatc caaagtggac aaagattaga
    67141 tccaagtacg tttgaaatta atcaaataca cttaggtgaa cagaaggttt atagaggaga
    67201 agagggaatc caacaatttt tacaagattt ccccagcgct acatttaatt tttcagtaac
    67261 tgataattac attgaaataa ctataccaaa aaactttgtc aatcttagga aaataatggt
    67321 gagttataag acgatcatag aaaacccaga acaaataaat tttgagaatc attcggaagc
    67381 ttggtttaaa gaatttaata aacctgctgt tgatggagaa agtttcaatc atacagttaa
    67441 aaatatttca gcttctggtg gagtcaacgg tacagttaga ggcgaattga agattttcaa
    67501 atatatcaat gacacagaga ttggtatccc aaatgtgact ttcgaattaa gacgagcaga
    67561 tgaacagcct attcaaggac agtctagtat cctgttgact tcgaatgaac agggagaagc
    67621 tagtatcaaa ggcctgcaag taggagacta tgttgtaaaa gaaaaagaag cacccaattg
    67681 gattgatttt gatccactaa gttcaaatga actcaaattc tccataaacg aaaatgatac
    67741 agagggagtc agtttaccta tttataacaa gaaaaaggtt acgaacatca cagcaactaa
    67801 aatttggaac ggtggaacca ctccaagacc gagtatttat tttaaattat tcagagcaag
    67861 tacaaacaat tgggaaccag ttcctgatgc agaaacaaaa cgattagaca atggaataac
    67921 ttcagtgact tgggaagata tccaacagta tgatgatagt ggaaacgaat atacgtttaa
    67981 agtgcaagaa gtagatcaaa acggaaatga ttatgtccct tcaggttatc aaaaaattga
    68041 aaacgggcta gtcgttacaa atgagaataa agaagtcatt tcagtctcag gacaaaaaac
    68101 atgggaagac aatgagaacc aagacggcaa acgaccgacg acgatcacag taaatctatt
    68161 agccgacggt caaccgatcc aacacaaaga agtaagtgaa aaagatgatt ggcgctatcg
    68221 tttcacaaat ctgccaaaat acagagacgg gcaagaaatc atctatactg taacggaaga
    68281 caacgtgccc gaatacagta cgacgattga cgggtataac atcaaaaaca gttatacacc
    68341 ggaaaaaaca aatatatcta taccaggtag ccatataaca ccgtggaaaa attttccaga
    68401 gaagacagag agagagaaaa ttagaaatct attctctcaa aaattgcaaa tatttgctca
    68461 tacaggagaa tccagcgaac aaagaagcaa ttatattagt aagagagctg tacctaaaca
    68521 gataacaaat aaatcaaaaa gcattcttcc taaaacaagt agtaaaaaat ctagttttgc
    68581 tgtaatcatt ggtttattga tagtaactat ctgtgctggg atattcttac aaaaatataa
    68641 aaaagtttag ttagaatata atattttttg ttaaatatga ctgaaatcaa aagaataaaa
    68701 ttccgattta taatcgaaaa aagaagcatt tttatatatg cttctttttt cgtagaatca
    68761 ataaatatgg atttggctaa ctatggaaga atactcgtat tagttttcag cgttcatact
    68821 agttgttaca ttgtttgatt ggccaaaaga atttctgata tattttgtgc taaataaaga
    68881 aaaagacgct tgaattggga aataagaaaa ctactctatc attacaaatt ttcataaact
    68941 ggcagatgtt ctaagtaaac aagtatcttt tcaaagtcgg aaaaatccat aatcaacgta
    69001 gtggtattga tatttggatg aaagcctacg gtatcttgac gatcaatagc agcatcgatc
    69061 acgacttgga tttttttctc tttgtcgtgc atcaatgcta atggagtcac tgtacctgct
    69121 ggaacgccta ggaggtcagg aagctgttct tcagaaacaa aagataagcg cttttctttt
    69181 aattgttcag ctagttgttt taaatcggcg tgcttttcat caggcaagat gacaagatag
    69241 atttgttttc cttttcttga tttcaataat agatttttta cttgcggacc aggtagggaa
    69301 aaagggacat ttttgactga cgtaatcgca ggatgatcga ctttttgaaa agagataccc
    69361 agttttttta gtagttcata agcttcttgt tcggttgcac gactcatcgc gcatcaccct
    69421 ccttttttta ttagtgtatc ataaaaaaga gttgacaaat gaaaaataat catgtaaatt
    69481 acacgtaaag ttaaaacaaa tgacatcgaa aagaagagta gccgttaggt gtttttagag
    69541 agtctctggt tggtggaaag aggcagcagt taaccgtgaa acacatcttg gagtcgattt
    69601 tctgaagcgt atagtaggaa aatccgggga gcccgttaca gctgcggtcg ttgctagatg
    69661 accagataag gctggctttt ccgtgaggag tcggtaaaaa aaggtggaac cacgtgatta
    69721 acgtcctttg atcttcggat caaaggactt tttgttttca tctgaacggc aacgactgtg
    69781 tgaggttttt tctgcaagga aaaaataaac agaggtggaa ccacgtataa tacgtcctct
    69841 tggcatttgc caagaggatt tttttatttt aaaggaggaa aagaagatgg agtatttgat
    69901 tgaagttatg ccgcaattat tagtaggagc actcacaaca ttgaaattat ttttatttac
    69961 cttgattggc tcattaccat tagggattgt tttagcatta ggattgtctt tgcattttaa
    70021 gccgctacgc tacttgcttc aaacatatgt atgggttatg cggggaacac cgctgttgtt
    70081 gcaactgatt tttatttttt atgggttgcc gacgattggg atcgtttttg atcgtttcga
    70141 agcagcactc attgccttta tcttaaacta tgcagcttat tttgcagaga tctttcgtgg
    70201 agggatacaa tcgattcctc aaggtcaata tgaagcagcg caagttttgc aattaagtcc
    70261 ctttcaaacg gtgacgaaaa tcgtcatccc acaagtgaca aagattgttt taccttctgt
    70321 agggaatgaa gttatcaact tggtcaaaga ttcttccttg atctatatat taggtttagg
    70381 tgacgtaatg cgtgctggga aaatcgcgat ggaacgcgac gcgactttac tgcctttgct
    70441 aggcgtggca atcatctatc ttacattgac tggtattcta acaatcgtaa tgaaacaagt
    70501 tgaaggaaaa ttaaattatt accgctaact gataggagga agaaatatga ttgaattgaa
    70561 gaaagtgaac aaagcatttg gtgaaaaaaa aataatcaaa gatttgaatc taatcattcc
    70621 agatgggaaa acattagcta tcgtaggtcc ttccggtggc ggtaaaacca cgcttttacg
    70681 tatcttggct ggcttagaaa gttctgacag cggagaattt tatttagacg gtgtaccgtt
    70741 caacccattc gagcttaaaa tgaaagaaca agttgtagga gtcgtattcc aagacttcca
    70801 gctatttcca catctgaata tttttgaaaa cattacctta gcaccaaaaa tggtattgaa
    70861 acagacaaaa gaagaataca ccaaaaaagc agaagaatta gcggcttcat tagggattag
    70921 tgatttattg aatatctatc cttatcagct ttctggcgga caaaaacagc gggtagcgat
    70981 tgccagagca ttggctatga atccacgggt attggcttat gatgaaccaa caagtgcttt
    71041 agatcctgaa ttacgccagc aagtcgagcg tttgatccta tcattgaaag aagatggggt
    71101 aacccaaatt attgtcaccc atgatttagt atttgcagaa aatgtcggtg atcaattact
    71161 aaaagtttcc ccaattcatt aagaaaggag aagatagaga tgaaaaaaac cagttttcta
    71221 ttcgctttga tcgcaggtct tcttcttttt gcaggctgtt cgaacaaaaa aacttcagca
    71281 gataattggg cgactatcaa cgaagagaaa aaaatcgtta taggtttaga cgatacattt
    71341 gttcctatgg gatttagaga taaagacggg aagctcacag gatttgatat tgatttagcc
    71401 aaagcagtct ttgaacaata tgggattacg gtagactttc agcccattga ctggtcaatg
    71461 aaggaatttg aactgaacaa tggaacgatc gatttgatat ggaacggcta ttccaaaacg
    71521 ccggcaagag aaaagaaagt gcaatttaca aaaccttata tggaaaacga tcaagtgctg
    71581 atcacaccta aagaatcagg aatcacaaac tttggacaaa tgaataataa gagattaggt
    71641 gcgcaaaatg ggtcatctgg ttatgatgta tttacgaaac aaccagaagt attaaaagag
    71701 atagtcaaaa accaagatgc tgttttgtat gatagtttta atgaagcatt gatcgatctg
    71761 aaaagcagac gggtcgatgg tctgctgatg gataaagtat acgcagacta ttatttgaaa
    71821 caaagaaacg aactagaaga cttcaacata acaaaaggtt cttatgagag tgaggatttt
    71881 gcagttggtg cacgcaagtc agatagtaca ttagtgaaaa aaatcaatga agccctagat
    71941 caactagaga aaacaggtga attccaaaaa atatccgata aatggtttgg cgaagatgtt
    72001 acgccgagaa attaacaaat aggggactgt gacaaaagac gtgtcacagt ccctttttcc
    72061 gaataaacag tgttctcctg ccaactcctt gtgactcgga gctgaatggc aggctcacaa
    72121 cctcttggta aacggtgttc aaaagccagt ttttcggtat taagccaaat ttatgcaaaa
    72181 atgtagaaag ccattttcac aaaatttttc ttactactcg aaactaagcg actttttcac
    72241 aacctccttt acatattttt attttgttgt ggaaggggtt tcgtgttatt ctaaaagagg
    72301 aacgattgaa ggttatagga aaggaagaga tgaatggaac acaaagaact tacctcattt
    72361 ccaaaagatt ttctgtgggg ctctgcttct gcagcgtatc aagtagaagg agcttggcaa
    72421 gaagatggga aaggagaatc agtctgggat cgatttgtac ggatacctgg aaagacattt
    72481 aaaggaacga acggtgattt ggcagtagac cactatcatc gttataaaga agatattgct
    72541 ttaatgaaag aacaaggtct gaaagcttac cgcttctctg tagcttggac acggattttt
    72601 cctaatggac gaggagaagt caatcaagct gggctcgctt tttatgagag attgatcgac
    72661 gaattgattg aaaacgatat tgaacctatg ttgactttat atcattggga tcttccacaa
    72721 gcattgcaag atgaatataa tggttgggaa tcacgtcaga tcattgaaga tttcactcat
    72781 tatgcagaaa cattatttga ggcattccgc gggaaagtcc attactggat tagtttgaat
    72841 gaacaaaata tcttcacttc attaggttat ttgttagcag cacatccgcc aggtgtgaca
    72901 gacccgaaac gaatgtatga agttaaccat attgctaatt tagcaaatgc atctgtcatc
    72961 aataaatttc acgagttaga aatgcctgga aaaatcggac caagctttgc gtatacgcca
    73021 aattatccaa ttgacagtaa tcctgaaaat gttctggctg ctgaaaatgc agaagacctg
    73081 atggccaatt attggatgga tgtctatatg tggggaaaat atccgattgc tgccatgagg
    73141 ttcttagaag aaaaaggatg ggcaccaacg attgaagctg gcgatgcaga attgctagaa
    73201 tctgctaaac cagattttct tgggatcaat tactatcaaa cggcgacgaa tgcattcaat
    73261 ccattaaacg gagttggtgc tggaaaaatg aatacgacag gaaaaaaagg ttcatcagaa
    73321 gaaactggag ttcctggaat gtataaaaaa gttgagaatc catttgtcga acgaacaaat
    73381 tgggactggg agattgaccc agaaggatta aggatcggac tgcgtcgtat cacaagccgt
    73441 taccgcatgc cggtactgat tacggaaaat ggcttaggag agtatgacaa gttgacagaa
    73501 gataaacaaa tccatgacga ctatcgaatc aattacttac aaagccacgt caaagccatc
    73561 aaagaagcaa tttcggatgg agcagaagtc ctaggctatt gcacctggtc ttatacagat
    73621 ttgcttagct ggctgaacgg ttatcaaaag cgatatggat ttgtatatgt tgatcaagac
    73681 gaaacacaag aaggatcttt ggaacgatat aagaaagaca gttattactg gtaccaaaaa
    73741 ctgattgaag aaaatggaga gaacctttag ttcacatact taaaacaaga aggtacggct
    73801 ggatatggcc gtgccttttc ttgataaaat catttagaaa ttaagaaaaa ctgtaaaata
    73861 agctgaaaaa tgaaagaaag cgtcagttct ttcaaacaaa actttagttc ccttactttt
    73921 ttttgtataa tgaaacttga tgaaatgagg gataataaat ggcacaaaag aaacggccta
    73981 ctaaaaaaag gaaaaagacg aaaaaaacga aaaagcaaaa acagcagcag gaacaaatgc
    74041 tgacgattgg tgttgggttt gccttgattt tatttgctgt cttcggcttt ttaaaattag
    74101 gttttttagg aatattgatt gcaaacggct ttcggatcat tgcaggaaat acttaccaaa
    74161 tcctctgtct tttattagcc gtattaggat tttggattgt cattaagaat acagagtttt
    74221 caattggtaa aaaccgacgc tggtttggcg gcatactctt ttatttcggt atcttattat
    74281 tgttacatgc ccatttattt ggcaaactcc atactgggga accaaatatc atggggacga
    74341 catgggattt gttagccagt gatataaaac aaagtcaagt agacaataac gttggtggtg
    74401 ggatgattgg agcaatcctt tatcatttta cttacttctt gattgcacag cctggaagtt
    74461 atttagcagc agtgctatta ctggcaggag gagcattcct gttcagtaat ctggaaggct
    74521 atcagctgtt aaatggtatc caatcaattg gagaacgagt acaggaatta ttggaaggtg
    74581 atcctgccaa gcaagctcga aagcaagcgg caaaggaaga gagaatgaaa cagcgcgcag
    74641 aagcgaaaga agcaaggcgc ttagctgcaa aagaagctgc agaaaaagaa gctgcagaat
    74701 atgagaagaa aaaagcggtg agccagcaaa gggaaaatac tgctgatgaa tggcaggaac
    74761 cagaaaatac agagccggag cagctaagtt ttgttccaat cgacagtttt caagaaaata
    74821 tccatcctgc gaatctagag aaaccagtac cagatacacc aaaacagacc aatacagcag
    74881 aaggtttttc agatgagttg ccagaggatg acggtacctc attagaattt gagattgaag
    74941 cagaacagga aaatcaagac tatgaattac cgacagttga tttgcttgat tctataccaa
    75001 ctgtggatca aagtgatgag tataaaaaaa ttgaaaaaaa tatcggcgta ttagaacaaa
    75061 ctttccaaag tttcggtgtc gatgccaagg tcgtcaaagc cagcttagga ccatccgtca
    75121 caaaattcga agtccagccg gctgtagggg taaaagtaag taaaattgtg aacttaacag
    75181 atgatatcgc gcttgcttta gcggcgaaag atgtccggat ggaagcaccg attccaggta
    75241 aatcactgat tggtattgaa gtaccaaatg gaaagatcag tatggtttcc tttagagaaa
    75301 tcatcgaagc acaaccaaac cacccagata aattactaga agtaccttta ggacgtgatg
    75361 tttctggacg ggtacaaacg gctgatcttt cgaagatgcc tcacttactc gtggctggtt
    75421 cgactggtag tgggaagtca gtagcaatta atgggattat cacaagtata ttaatgcgtg
    75481 ctaagcccca tgaagtaaaa ctgatgatga tcgatccgaa aatggttgaa ttgaatatgt
    75541 acaacggcat acctcatctg ttgacgccgg tcgtgacgaa ccctagaaaa gcagcgcaag
    75601 ccttacaaaa agtagtacaa gaaatggaag aacgatatga aaaattcgcg gcaaccggag
    75661 taagaaatat ttctggttac aatgaatttg ttcaacagaa aaacttggaa aacggaacga
    75721 aacatccaac cttaccattc atcgtagtga tcgtagatga attagctgat ttgatgatgg
    75781 tagccagcaa tgaagttgaa gatgcgatta ttcgtttagc gcaaatggct cgggcagcgg
    75841 ggattcatat gatcctagct actcaacgtc caagtgtgga tgttatcaca ggaatcatca
    75901 aagcaaatgt accttccaga atggcatttg cggtatcaag cggtacagat tctcggacga
    75961 tcattgattc taatggggca gaaaagctct tagggcgagg agatatgcta ttcttgccaa
    76021 tgggtgagaa taaaccgatc cgtgtgcaag gagcattcat ttctgaccac gaagtagaac
    76081 gggtcgttca atttgttaca gatcagcaag aagctcatta tgaagagaaa atgatgccga
    76141 cagatgaagt tgaaacgaca ggtgctccag aacagccaca agatgagctg tttgaagaag
    76201 caaaagcact tgtcgttgaa atgcaaacgg caagtatttc ccttctccaa agaagatttc
    76261 ggatcggtta caaccgagca gcacgtttag tagatgaact ggaagctcat ggagttgttg
    76321 gcccgtcaga aggaagcaag cctcggaaag tattcattga gcaggaagaa acatcagaaa
    76381 cgttgccgga cgataatgac atgtaaaact tgtgtgatga agggttgaaa aacgaataac
    76441 caataaaaag acaaggcatg atgataccaa aagaaaaaat ggtttttttc catcttttct
    76501 aatacggtat gatgtcttgt ctttttagtt tttgtgagat taaagttcta ttcgatttat
    76561 ttgtgaagta ttgcattaag gaaatgaatc atgtatagta tgtagcgaaa ctttgagaaa
    76621 aagagggaaa atactttgga aaaacagtcc atttatggct tgacgaatga agaattaatc
    76681 aattggttta tagaaaacgg cgagaaaaaa ttccgagctg cccaagtttg ggaatggttg
    76741 tatcaaaaac gtgtaagtaa tttcacagaa atgacgaatc tatcgaaaca attgatcgaa
    76801 aaattatcgg agcattttat catcaatcct ctaaaacaga tggtcgtcca agaagcttcg
    76861 gatggtacag taaaatattt gtttgaactc cctgataaaa acatgattga gactgtactg
    76921 atgagacaag aatatggctt gtcagtttgt gtgacgacac aagtaggatg taatatcggc
    76981 tgtacgtttt gtgcaagcgg gctgctcaaa aagaaccgtg atctgactgc tggagaaatt
    77041 gttgcacaga tcatgatggt ccaacattat tttgatgagc gcaatcttgg cgaacgcgtt
    77101 tcacatgtcg ttgtaatggg gatcggtgag ccatttgata attacgacaa tgtaatggac
    77161 tttttgcata tcatcaatga tgccaaagga ttggcaattg gtgctcggca cattacagtt
    77221 tccactagtg gattagcaca caaaatcaag gaattcgcta ataacggctt gcaagtcaat
    77281 ctggctattt ccttgcacgc gccgaataat gaggtgcgaa catcgatcat gcggatcaac
    77341 cgaagtttcc caattgagaa attgatggaa gctgtggatg agtatttaga gaaaacaaac
    77401 cgtcgaatca cgtttgaata tatcatgttg aatcaagtaa atgatagacc agagcatgcg
    77461 caacaattag cagatctatt aaaagataag aaaaaattag catatgtcaa cttgattcca
    77521 tataatccag tcagtgaaca tgatcaatat tctcgcagtc caaaagctga tgtattgaga
    77581 ttttatgatg tattgaagaa aaacggcgta aactgtgtga tacgtaaaga acatggtaca
    77641 gatattgatg cagcttgcgg acaattgcga agcaagcaaa tgaaaaaaac agttgccaaa
    77701 taatcgtatc ctactcgttt tttcaattac cataaaagga gcagttttct taattaagga
    77761 actgttcaac ttaaataaga gaaaagattc tatagcgaaa gctataaagc tttttttgac
    77821 aagaaaaacc ctcatcaagc aaagaaatgt cctcaatttg atgacagcct gcttgatggg
    77881 ggttttagca attatttaac tgattttctt atatccttgc tggctttctt gtgtagcatg
    77941 ataagtttct acgtcaagaa tggcctgttt aaatttttct cgggtgattt cataaggcac
    78001 atgtttaata tcatttgttg ccatggcttt atctaagatt gcttctaaat cggtcgtgac
    78061 attgagattc atgtcggtta acgatactgg aagttggttc tttttcataa acacatagat
    78121 tttatcaaac aaatcgaact gctgatccat catcaataag gtcagtacac cataactgac
    78181 agatgctccg tgaaggtatc cctccatttt ttctagaaca gtcgtaccgt aatagaatga
    78241 gtgtgccata gcagaattat agttattgtt aactaaaaca gaaaccaatc cggtagtaac
    78301 aatgatatcc gaaacgactt gttcaattgc atatgaggga cgatcgtcgg cactatcttt
    78361 caatgcttgc gtaccataag tcaagagacg atcaatgcac atttttccga tttggattcc
    78421 taatctatcc gtgtagccta gatcatcgcc acgagcagaa aaagtagatt cgacttcttt
    78481 ggataaagca tcgccaatac ctgcccataa gtatttatca ggtgcttcgg caataattgc
    78541 tgtatcaatg aaggtgtgta caggtggttt tgaaggaaag aagagtccgt ccattacgcc
    78601 ttcttcgtta tagatgacac ataccgcagt gacgggcgaa cagttcgaac caatagtggg
    78661 aaaggtgaag actggtttag ctagtttttc accaatgact tttacagtat cgcaagcacg
    78721 gccaccaccg actgcaaaca ggacgtctgc tttttggaca ctttcatgct ggatcaactg
    78781 ttcaatattt ccataagttg aattaccccc gtaccagaga ctggcgacaa cctctatttc
    78841 ctgtgtcaaa gctactttta ttttgttttc tgcctttgaa agtgcagtct tccctccaat
    78901 cagcactact tttgtcccat attctttgac gattccattt gctttttcat acgcatctgt
    78961 tccaatggta taatttggta agaaaacact ttgactcata ttcatttcct tctttcttcg
    79021 ttgaaacggg ttaaaatttt aaagagtgat cgatctgact gcggctgtag atggagtaga
    79081 ggtgaaccta agacaggata agtgatgaat aaggtggcat gaacaccttg aaatcatcaa
    79141 taagtatcct aaaaacgaac aagtacaaaa acattgaaaa cgacaataat gaatttttgt
    79201 tcctcttagt atttctaccg attccctttg cttttttgta attatctaaa aattctaaaa
    79261 attaagatta ttatatgaaa acaggtttta tttgtcaatt cataattggt tttttttaaa
    79321 gcaaaagata atctatatca tgatgaacaa acagagtttt ttcctccaat tgatggcttt
    79381 cctgatcttt cctattttga ataaagtgtt tctgtataat ttttttattt tataagtaag
    79441 ataaataatg aaagaataga gatactgatt ggtagctaaa gatttttgag cgagaacatt
    79501 tcgttttttc aaaaggactg ttagaataag caagaacaag ggggaagacg tatgataatc
    79561 agtgaatttg accgtaataa tccagtattg aaagatcagc tttctgattt actgagactg
    79621 acttggccgg aagaatatgg agacagctcg gcagaagaag tagaagaaat gatgaatcca
    79681 gaacgaatcg cggtagcagc ggtagaccaa gatgagttag taggatttat tggtgcaatc
    79741 cctcaatacg gtatcacagg ttgggaattg catccattag ttgtagaaag ctcccgacga
    79801 aagaaccaaa taggtactcg attagtcaat tacttagaaa aagaagtagc ttccagagga
    79861 ggaatcacga tttatttagg tacggatgat ttagaccatg gaacaacgtt aagtcaaacg
    79921 gacctgtatg agcatacatt tgataaagtg gcttccatcc agaaccttcg tgaacatccg
    79981 tatgaattct atgaaaaatt aggttataaa atcgtaggtg tcttaccaaa tgcaaatggc
    80041 tgggacaaac cggatatttg gatggcaaaa acgattattc ctcgaccaaa ttctcaataa
    80101 taaaaagagg ttgtgacaga agtaatcagc ttcaagaaat aagaaggaat ttacgaaaat
    80161 tacttcttga atttttgtga aattccaact tatttccgaa gaagctactt ttggaacacc
    80221 gtgtaccaga ggttgtgaaa aagtcgctta gtttcgagta gtaagaaaaa ttttgtgaaa
    80281 atggctttct acatttttgc ataaatttgg cttaataccg agaaactggc ttttgaacac
    80341 cgtttattca gataagggac tgtgacaaga cttttgtcac agtttctttt tgtttattct
    80401 tttttatctt tgtatggcaa taatagacaa tataacgaaa attatttaat ggcttttgga
    80461 agaccatgga aaaccttgta caaagctatt ttttctgaaa aattccttga aacctcacga
    80521 aaaaatcatt attttatgaa aaagacaaaa aaaagtgttg attttttaat aattattcat
    80581 taaactctta aacaacttca gaaaatatta attattctga aaattccaat aaaggggtac
    80641 gtaaaatgaa aaagaaattt acatttggtt tggttgcggt atgcggcctt gtacttgctg
    80701 gatgttatgg cggcagttca gccacaagca gtagttcagc aaaaagcggt tcagcagatg
    80761 gaggaggcgt atttaactta gtcgtgcctc aagaaatgcc tacagctgac ttatcagttg
    80821 caacagatac aatcagtttt acagcattga ataacgttta tgaaggaatt taccgtcttg
    80881 atgaagacag caaaccacag ccggcaggag ctagcgagtt ggcagaagtc agtgaagacg
    80941 gattaactta caaaatcaaa ttacgagaag acgcaaaatg gtcaaatggt gatcctgtta
    81001 cagcagcgga ttacgtttat ggctggcaac gaacagtaga cccagctaca gcttctgaat
    81061 atgcttacct gtatgcgcca gttgaaaatg cagaagacat tacagctgga aagaaagata
    81121 aatcagaact agggatcaaa gcagttggtg actatgaatt agaaatcaaa ttgacgaaac
    81181 aaacaccata tttccaatat ctgcttgctt tcccatcatt tttcccacaa aaacaatccg
    81241 tagtggaaga aaatggggat gcctatgcat ctgcaagtga taaagctgtt tataatggac
    81301 cattcacatt agaagatttt gatggaccag gaacagatac agaatggact tataagaaaa
    81361 atgatcatta ctgggacaaa gatacagtaa aactttctga aatcaaagtc agtgtagtaa
    81421 aagaatcttc tactgcattg aacttattca aagatggcca agcagatgac gtgatcttgt
    81481 ctggtgagtt agcacagcaa aacgcaaacg atccagctta tacttctgtt aaagaagcgc
    81541 ggacaagcta tatcgaattc aatcaacgtg aaaagaattc accattcaac aatgtgaacc
    81601 taagaaaagc tatttcttat tctatcgatc gtgaagcttt agtaaaacaa gtactaggtg
    81661 acggatcagt tgtctctaca ggattgatcc catcagatat ggtaaaaagt ccaacaacga
    81721 acgaagactt tgcaaaagaa gctggaaaat tagtttctta tgacaaagat aaagcaaaag
    81781 aatattggga aaaagcgaaa aaagaattgg gcgttgattc tttagaattt gatttgatgg
    81841 cttctgatga tgattcatcg aaaaaagtaa tcgaatatgt tcaaaactca atccaagaaa
    81901 acttggatgg cgtaacagtc aaaccaacac ctgttccatt ctctgtacgt cttgaccgct
    81961 caacttcggg tgattttgac gcagtactag gcggatgggc tgctgactat gcagacccaa
    82021 gcagctttac tgatttgttt gtcacaggta attcatacaa ccgtggtcgc tggagcaatg
    82081 cagaatatga cgaagcagtt aaagcagctt catcaacaga cgctggcgat gaacaagccc
    82141 gttgggatga tttccaaaaa gcaatcaaga tcatctctga tgatatgggt gtcgttccgg
    82201 tgtaccaaaa agcagaaggt cacctagtga atgaaaaaat caaaggtatc gttcaccatg
    82261 cggcaggcgc ttcatgggat tacaaatgga catacgttga agaataatcg ttaataccgt
    82321 gagcatgaga aaaaacgagg ctgcggcaaa tgtcgcaacc tcgttctcat attcacttat
    82381 cctaacaaag aaaaaagcat gaaaatagca gaaagagcaa ttagtattcc ggcaatgatc
    82441 agccaaaagc tgtacatacc gtagctggca gacgagagcg aggaaaattc tggttttttc
    82501 tttcggttcc ttgttcgtgc aagatggacc gatcgctgaa aatgatcgaa gaaacccgaa
    82561 gaaaagaccc ataaaaaacc gccgataatc agaaacggca atgaccataa gaatagatca
    82621 ttagataatt gaatgagtgt aaaggaatgg ttgatgagat tttttattaa aataaccaga
    82681 atcagtagaa aagctactgc gtaggggata gatttttttt tcatttgatt gctcctttat
    82741 ttttggttca ttatctaata atgtagcgaa acatctgtca gaagtcaaaa gctaggggga
    82801 aacattagtg aatagttata tcaaatatgt attaaaacgt gtctttttca tgatcatcac
    82861 gctttggtta attgcaacaa tcaccttttt cttgatgcaa ttgctgccgg gcacgccata
    82921 tacgaatcag gaacgtttga gtcctgaaac aatcgagatg ctaaataaac aagtcggttt
    82981 ggataaacca gttatcgtac aatatgggat ttatctttct aatttgcttc aaggagattt
    83041 tggaatttcc ttccaattta aaaaccagcc agtcgcacat ttgttagctg gaagaatcgg
    83101 accatccttg cagttagggt tacaggcaat tatctttgga acagtcctag ggacgatttt
    83161 aggaacgatc tctgccatga agcaaaatac atgggcagat acatcttcta cactcgtagc
    83221 gatattaggt cgttccattc caaactttgt atttgctgtt ttattacaat atatctttgc
    83281 aatcaaatta caagttttgc caatcgcaaa atgggatggc tttgtgtaca caatcttacc
    83341 aacaattgcg ttggccatgt cgccgcttgc tgactctgct cggtttatcc gtacggaaat
    83401 ggtggaagta ctgcatagtg attatgtgga attagcaaaa gcaaaaggat tgagccgttg
    83461 ggaaatcgcc tttaaacatg gtcttcgaaa tagtttgatt ccattgatga ctttattagg
    83521 accgttagct gtagcattga tgaccggatc actggtggta gaaaatatct ttgctattcc
    83581 tggtatcggg gaacaattcg ttaagtcaat cacaacaaat gattatccta cgatcatggc
    83641 tgtaacgatc ctttactcat ttatgctgat ttttgttatt ttgatcgtgg atctattgta
    83701 cggtctagtt gatccaagaa ttcgtgtttc agaagggagc cgaggataaa tggaaatgat
    83761 accaaagcgt tatgaaacag ttgcagatat ccctgcggat gaatttcttc cattacaaaa
    83821 aaataccgaa gaagaacgtg aacagattac tgcaccttct ttgaatttta tccaagattc
    83881 atggcgccgt ttaaagaaaa acaaagctgc cgttatttca atggttttac tattggtcat
    83941 cattttgatc tctgtgatca caatctttgt ttctcctcat gatccaactg cccaaaacgt
    84001 ggcttatatc aatttgcctc ctcgtattcc gggaatcaat atcgatggat tgaatggaaa
    84061 agcaatggtt ggtggtgaac ttgttgataa atatgctcaa gcaaacgtcc cttcaaacgt
    84121 aaatttcttt ttaggaacag acggtttggg acgtgatgta ttaagccgct tatttatggg
    84181 aatgagaatc tcgttgctga tcgcatttat tgctgcatta ctagatgtaa cgattggtgt
    84241 agcttacggg ttggtttctg gtttgttagg cggacgtgtc gataacgtga tgcaacgttt
    84301 tttggaaatc ttatcaggaa ttccaaacct cgttgtcatg attttgatgt tggtcgtttt
    84361 tgaaccagga attttttcaa tcgtggctgc tatggccatc acaaactgga taccaatggc
    84421 acgtatcgtt cgtgcacaaa caatgaaatt aaaagatcaa gaatatgttt tagctggatt
    84481 gacattaggt gaatcaagaa tgaaaattgc attcaaacat attttgccga atatctctag
    84541 tgtcattatt attcaaatga tgtttagtat tccatctgct attttcttcg aagccttttt
    84601 aagctttatc ggtttaggtc ttacgcctcc gtcagcttca ttaggaacga tgttgagcga
    84661 agggtacaag acattcctgt atctgcctta tctattatgg attccggcag taactttatc
    84721 ggttatcatg attggcttta acttacttgc tgatggattg cgtgatgcct ttgatcctaa
    84781 aatgaaagag tgaagacgat gacgaaaatt ttagaagtga aagacttaga aatctctttt
    84841 gatacgtatg ctggaaaggt acgagcgatt cgcggtgtca attttcattt gaataaagga
    84901 gaaacattgg cgatcgttgg ggaatctgga agtggaaaat cagtgacgac cagaagcatc
    84961 atgcgcttgc tgtcaagcaa cgccaatata gatgctggtc aaatcctctt taaaggtaac
    85021 gatatcgttg gaaaatcaga aagagagatg caaaaaatcc gtggtaaaga aatagcgatg
    85081 attttccaag atccaatgac ctctttagat ccgacgatgc ccattgggaa gcaagtcgct
    85141 gagtccctta gaaagcataa taaagtttca aaaaaagagg gacaaaaagc tgcattagaa
    85201 ttgcttaaat tagttggaat acccgaagct gagaaacgta tcaacagtta tccgcatcag
    85261 ttctcaggag gtcagcgtca acggatcgtg atcgcgattg cactggtatg ttatccggaa
    85321 atcctgattg ctgatgaacc tacaacagcg cttgatgtga ctattcaagc acagattttg
    85381 gagctgctga aagaaattca gacaaaaatc gatacatcaa ttatctttat cactcatgac
    85441 cttggtgtag tagcgaatgt cgctgatcgt gtcgctgtca tgtatggagg aagaatcgtt
    85501 gaagttggaa catcggaaga aattttctac aacccgcaac atccctatac ttggggactg
    85561 cttggttcaa tgccgacatt agatagtgcg aacgatcgat tgtatgctat tcctggttct
    85621 ccaccggatt tattgaaccc gccaaaagga gacgcattct atccaagaaa tgaattcgcg
    85681 atgaaaatcg atgcagaaca agaaccacca ttttttgaac tatcaaaaac acacaaggca
    85741 gcaacttggc tacttgctcc gcaggcaccc aaagtgacac cgccagaaga aatccaacgt
    85801 cgctgggcta tctttaaaga gaaacaaaaa catacttacg gtcaaggagg aattgctgat
    85861 gccaaataaa ctacttgaag ttaaaggatt gaaacagtat ttcaatgtag gaaaaaagaa
    85921 tgaagtacat gctgtaaatg acatcagctt tcacatttat gaaggagaaa cattcggttt
    85981 agttggagaa tctggaagcg gaaaatccac tactggccgt acgatcattc gcttgaatga
    86041 acctactgat ggtgagatat tattcgacgg tcaagatata acgaagatca aagataaaaa
    86101 aggtttgacg aaattccggc atgatgttca gatgatcttt caagatccat acgcttcgtt
    86161 gaatcctcgt atgaaagtca gagatatcat tgccgaagga attgatgtta atggactagc
    86221 taaatcatct gaagagcgtg caaaaaaagt cgatgatcta ttgagaactg ttggattgaa
    86281 tccaagccac ggtactcgtt atcctcatga attttcaggt gggcaacgcc agcgtattgg
    86341 tattgcacga gcattggcag taaaaccgcg ttttatcatt tgtgatgaac caatttctgc
    86401 actagatgtg tcgatccaag cccaagtggt caatttgttg caagatctcc aaaaagaaca
    86461 tcaattgacc tatctattta ttgcacatga tttgtcgatg gttaaacata ttagtgaccg
    86521 aatcggtgta atgcataacg gcttgttatt agagatggga acaagtgatg aaatctataa
    86581 tcacggtgtt catccttata cagaaagttt gttatctgct attcctctac cagatccaga
    86641 ccatgagaga aaacgcagaa gaatcaaata tcaacctgaa ccagatgacg gacaagtacg
    86701 tcaacttcgt gaaatcgcac cagaacattt tgtctatgca actgagcagg aagtcccata
    86761 ttacgcaaaa aaactaaaac gacaaaagga atctcttctg gttgctaact aggagggaca
    86821 tagatgctaa aagcttttaa attccgtatg tatccgacag aagaacaaaa acagcaattg
    86881 attcgtactt ttggatgtgc tcgatttacc tataaccatt tgctgaaaaa gcggcagaaa
    86941 agttggcaac aaacaggagt agccaatttt tcgctcacac ccgctacatt aaaaaaagaa
    87001 tacccattct taaaagaagt agacagtctt gctttagcaa atgcacagct taatttggat
    87061 cgggcttttc gcaattattt caagggacgt gccagcttcc caaagcttaa aacgaaaaaa
    87121 agtatgtggc aatcttatac gaccaacaac caaacccgta cgatctatct ggaaaatggc
    87181 tacttaaagt taccaaaaca aaaagaacta atcaagataa atcagcatcg gccagttgaa
    87241 ggatcgattc gctccgctac gatttctgct cgatataatg aagaatttta tgtcgcacta
    87301 ctttgtgatg tttcgccagt aaaaaaagaa tctttagcta aatggatcgg gatcgcctat
    87361 catccgaaga cattgatcca aacatctcga cctctagaag taactttacc aaaatttcac
    87421 cagacagaag aaaagctgca acatgcacag cggaaattga atgtgaaagt ccgctccgct
    87481 caccatagaa agatcaggtt agatcaggca agcaattatc agaaacaaaa gagaaaagta
    87541 atggatcttt atctgaaaca aaagaaccag cgagaagatt atcttgaaca attatctggg
    87601 aaattggtca aacaatatga ctacttattt gtagaatctt ttccaaaaga agaggcacat
    87661 gctgattttt ctattcacga ctggcataaa ttaataacaa aattgcgtta taagtcccaa
    87721 tggtataata aaaaatttct tttgatcaat accgacggag cagaagaaag caattccgta
    87781 agaaagagcc aagtagtaga aaaaatgggc agacattcgg ttatcaaggg ataaaaaatg
    87841 aatgaaactg ataggagcgt tagggttagc cttgttaata aaaagtctta atgacttttg
    87901 tttctaggaa tttttctttt gaagaaaagc tcactaatta tgacaaacca ataaaacaat
    87961 agcagaaaaa gttcgtacga gctttttctg ctattgttaa ttttttattc agaaagttta
    88021 cgaatacatc aaaattctga aacaaaaaac gtaactcaca aagagttgtt tttgcgtttt
    88081 ttcttgaatg attaggtctg aatcttttgc tcacaacctt attcatggtg ccccggcttg
    88141 agctgataga tttttgaagg acggccgatt cctacaggac gttcaccgat ctcatcgaaa
    88201 tattggagca tagctttctt aaaattggaa tgatcgatcg ttttataatc gatccctaag
    88261 aatttagcaa atacttttcg agcttccgta atcgtgaaat ctttacctaa aacttgtaga
    88321 acttgcggct cgtgttccat tttattgact acacggttga atgctttcaa gatgatttga
    88381 ctatggtcaa aagccaaagt atctttgcca gaagactctc cagtgactaa atcaagcgag
    88441 atagccactt ctccgctaga taaatggatc ttgttactat gacgttctag tgtgaaccag
    88501 cgtacttcct tggcatcatc tccggcgatt agcggttctt ctccaataaa ggctaagtag
    88561 ctgactgtga cgacccagcc tcgcggatct cgattaggcg tactgaatgt atgcagttgc
    88621 tcaatatttt cttttgaaat aaccacacca gtttcttcct ttgtttctct taagacgctt
    88681 tctccagttg actcatcctt ttggacaaag ccaccaggca atgcccatga atttcgataa
    88741 ggatgccctt ttctttggat caacaaaact ttcagctgat cttcttcttt gttatagcac
    88801 atcagtacga tatcgacagt caaagagggc ttgtcatatt ctggacgttc ctgtttttga
    88861 taccagttaa gaaattcttc ttcacttgct ttatgttcat aatataattt ttcttcttct
    88921 ttagaagcaa aacggttcat ctgaccacct ccattgacag taaaagtact ttttacctta
    88981 ttgtagcaga ctctgaaaaa aaaccaagga tttacttgaa aaatctaggt tatcatttaa
    89041 atatgaaaaa taaatggaag tatgagattg aataaaaaga aaagcagata aaacggcaat
    89101 actttatacc gctcttcacg aatggcaaag aagccacaaa taacgatata tacgtcaatg
    89161 ataaaacgca aaatccaagc tgctgtcata aaactgttca aatgcccatg gaggttaaaa
    89221 taaccataca tacgaatata aaaatagctg aatattaaat gtgctaatga aagaaaagca
    89281 atactaagtg taaaaaaaag atgtttcttc tgcatgattg ttccagtccc ttactaagat
    89341 agatagtctt tattatacca cgtgtgaggg gagaaataaa aagccgtttt ttagtagata
    89401 tgaaacaaaa caaaaacccg catttattca acctattcat ccttttaaag gatagattga
    89461 acgtagatag aagtcgttta tccagtcttt ttcattttga aaaaaagcta acagcatgct
    89521 ttttttatgg tatactagca aggaaacgaa ttcgcatcat gcgataaagg aggaagagcc
    89581 ccgtggcaga aaaggaaact ttttatatca ctacgccaat ctattatcca agcggcaaac
    89641 ttcatatcgg caactcgtat actacgattg catgtgacgc aattgctcgt tataaacggt
    89701 tgatgggctt tgatgtgttt tatctcactg gagtggatga acatggtcaa aaaatcgaaa
    89761 caaaagcaga agaactaggt gtaaaaccgc aagaatatgt agataaaatg gcggctgatg
    89821 tcaagaaatt atggaaaacg cttgatatca gttatgataa attcattcgc acgacagatg
    89881 attaccataa agcagctgtt caaaaaatat ttgatcgttt attagaacag ggagatattt
    89941 acttaggtga atatgaaggc tggtactctg tttctgacga agaattcttt acagaaacac
    90001 aacttgcaga agtgtacaaa gatgacgaag gtaacgtgat cggtggtaaa gcgccaagtg
    90061 gacacgaagt agaattggta aaagaagaat catacttctt ccgcatgagc aaatacgcag
    90121 accgtctatt ggaatactat gaagaacatc ccgaattcat ccagccagaa tctcgtaaaa
    90181 acgaaatgat caacaacttt atcaaaccag gattagagga tcttgcagtt tcacgaacaa
    90241 cttttacttg gggagtacca gtcaagagtg atccgaaaca tgtggtgtat gtatggatcg
    90301 atgcattatc caattatatt actgcactag gatatggctc cgaagatgaa agtctattcg
    90361 aaaaatactg gcctgcagat gttcagatgg tcggtaaaga aatcgttcgc tttcatacga
    90421 tctattggcc aatcatgctg atggcccttg atttgcctct acctaaaaaa gtatttgggc
    90481 atggctggct attgatgaaa gacggaaaaa tgtctaaatc aaaaggaaat gtcgtttatc
    90541 ctgaaatgct tgtggaacgt tatggtttag atgcactccg ttattatttg cttcgtgctg
    90601 ttccgtttgg gtcagatggt gtctttacgc cagaagattt tgtttcccgt gtcaattatg
    90661 atctggcaaa tgatctaggg aacttattga atcgaacgat tgctatgatc aacaaatatt
    90721 gtgatggact cgttcctgac tatgcctcac ttgtcactcc atttgatagt gaactgtcta
    90781 cgacggctgc taacgttgtc ggacgttacc atgatgcaat ggaaaaaatg gaattcaata
    90841 cagcattggc tgaaatctgg gtgctgattt ctcgtgcaaa caaatacatt gatgaaacag
    90901 aaccatgggt attagcaaaa gacgaagaaa agaaagctga attgaatagt gtcatgatcc
    90961 atttagctga atctttgcgt atcgcagcga tattacttca gccaatcatg acagaaacgc
    91021 cagagaagat cttcaatcaa ctaggattgg actctgaaac aatgaatctt gaaggattac
    91081 actttggcga atttccttca ggaacaaaag tagttgcaaa aggtacacca atcttcccac
    91141 gtttagatat ggaagaagaa gttgctttta ttcaagaaaa aatgtctgaa ggtactcaaa
    91201 caaacgaaga tacagtcaaa tgggatccag aagaaacaga acttgtttca acgaaagaaa
    91261 aacaaatcaa atttgatgta tttgaaaaag tagaactaaa agtagcagaa gtcatcaact
    91321 gtcaaaaagt agaaggggca gataagttgc tgcaattccg actagatgct ggagacagcc
    91381 aagaccgtca aatcttgtca ggaatcgctg aattttatcc tgatccaagc gaattgatcg
    91441 ggaaaaaagt cgtcattgta gcaaatctga aaccacgaaa gatgcgtgga caaatcagtc
    91501 aaggaatgat cctttctgca gaagcaccag atggctcttt acaagtaatc gaagcaccaa
    91561 aatccatgcc aaatggctca gaaatcgcat agaaattcaa agggggtatg acactagttg
    91621 tgtcataccc cctttttccg aaatttgaga agcaattttc gtaaattcct tcttattact
    91681 tgaagccaat catataatac agaaacagag aactatccaa aataaatcct agaaaaagaa
    91741 gtacgagctt cgctgatttt tgttaattta gaataatact aataggaatc gtaaaaacag
    91801 aaaaaaagca taatgataaa gggtcgggca gattttaatt gattcatctg gtactctttt
    91861 ttattgtcct tacattcata aagtttgaat gcaatgactt tattacatct atatttatat
    91921 ctaacagtag cgttgatgtg ttaattataa gttctatcac tttatgttca attagtttgt
    91981 gctcttatat gtgtgattga aaatatagat aaaaaaacaa tcatcggctt tgacttcgat
    92041 gattgttttc tttattttgt aaaaatccta tcacttgatt ttatggtaac cttttatttt
    92101 tgtcttcaaa cggcttggta agagagcagt aagcagtgca aatgggatcg aaaagacata
    92161 ccagaaaatc gtacgtccga taccataatg ttgatagagc tttgtcaaca tcacgtgtaa
    92221 caagatcaac cctaaaagca aggagccagc tataaaccaa tgattatccc aatgcatgac
    92281 ttcactaagt gccatcactc caaaaggata gaaataaaaa tagatcccga ctaaggtcat
    92341 ccgccagttc tttgtaaatg ttccgatatt caataaaaag aaaatcgctg aaagcaaaat
    92401 accgataggc ggaaaaagcc caaccaaaaa ggaatacaac atcccccaca agatcatcac
    92461 aggacctttg atcaatgcaa cgattgcgat gaacaaagtc agcaatatta gtttttgtga
    92521 taacgttgca acagtcatta atccaaataa aattaatgtg aaccaatgcc aatgggactg
    92581 ctgttgttct ttacgggaaa aatcgacccg gttggataaa taatctgcta atttcggata
    92641 agaacgctta aaatccataa actgttcctc cttcgtggaa aaggtaggtt tagtatacga
    92701 aaaataaaaa agaaatacat ccgtcttaag agggagtttt tcactgaaag tggagaaaaa
    92761 agaatggtaa attaaaatat tctcagttat actgaaaatt ataccaaatt tcaaagaaga
    92821 aagaggatgg gaatgaaagg caaactaaaa cgagaaatca atctgtttgg cgcattagct
    92881 accgttatgg gaaccgtgat cggtgcaggc gtcttcttca aaactgctgc tgttactgct
    92941 agtactcagt ctacaagttt gacattgcta gcttggcttt tgggtggttt cttaacgatc
    93001 tgtgctggat tgacagtggc tgaattagct acagcaatcc cggaaactgg tggagctgta
    93061 aaatatattg aagctgcgta tggaaaattg cccagctttt tattaggatg ggcgcaaagc
    93121 ttgatttact ttcctgctaa tattgctgca ttatcgatta tctttgcgac acaattgacg
    93181 aacttattac aattatctac cgattatctt ttgttgattg cagtgatcac cgctgtttct
    93241 gtgacagggt tgaatttgtt agggacaaaa gtcggtgctt ctgtacaatc agtgacgttg
    93301 attgttaaat taataccaat tgctgtgatt gtcatatggg gattattgac cccaggacaa
    93361 ggaactgtcc agttatttcc aatcgaagct ggaaaagatg ttacttttgt cgaaggattg
    93421 agcagtgcgt tgttagcaac gttgtttgct tatgacggct ggttaggtgt cggtgcaatg
    93481 gcaggggaaa tgaaacggcc ggaaaaagat ttgcctaaag caattattct tggtttgagt
    93541 tttgtaacag tcgtttatct attgatcaat tttgtttttt tgaaaacttt gccgattgat
    93601 catcttgccg gtaatttgaa tgcagcttct gaagcatcag acgtcatttt tggaggaatc
    93661 ggtggaaagc tggtcactat tgggatcttg atctcggtat acggtgcatt gaacggttat
    93721 acactaactg ggatccgcgt gccttatgcg atggctttag aagacgagct acctttcagt
    93781 aaacagctga caaagctttc aaagaagttt acggttcctt atgttcctgc ggttttccag
    93841 ttagcagtag cttgtattat gatgagcctt ggttctttcg actttttaac agacatgttg
    93901 atttttgtga tgtggctatt cagtttactg atttttatcg gtgtctttat tttaagaaaa
    93961 aaagcgccgg aattgccacg tccatataaa gtaccacttt atccaatcgt tccgattatt
    94021 gcgattctcg gtgctatttt cattttaggt atgacgatga tgacgcaaac gaaattagca
    94081 ttgatcggta taggtgttac cttgataggt atcccagtct attatcaaaa aaagaaaaaa
    94141 cgctcagaag agtaaaatat ttcaacaaca gacagaaaaa gtacgaacta ggtcctctag
    94201 atcttcgtgc tttttctatt tcaataaaac aagttcttct attttgattt ttgctacttc
    94261 tgcaagtagt gcttatgtgc taaagtaaga atgaaaagga gagataaaca tgatatttga
    94321 ttctcatacc catttaaatg ctgaacagtt caatgaagat attccagaaa cgattcagcg
    94381 agcacaagaa atgggggtaa cgaaaatggc ggtcgtgggc ttcgatacgc caacgattga
    94441 aaagtctttg caattaagcc atgactatcc aaatatatac agtattatcg gctggcatcc
    94501 gacagaggct ggcagttata cgaaagaaat cgaaaataaa ttacaagaac aattgacttt
    94561 accaaaggtt gtagcattag gggaaattgg cttggattat cattggatgg aagacccgaa
    94621 agaagtccaa gataaagtat ttcgcagaca gattgctatc gcaaaagaaa tgaacctacc
    94681 aatcagtatt catactagag aagcacttga agacacgtat caaatcctaa aagaagaaga
    94741 tgttcgagat atcggtggaa tcatgcatag tttcagtggt gattatgaat gggcaaaacg
    94801 atttcttgac ttagggatgc atatttcatt tagcggtgtc gtcactttca aaaaagcatt
    94861 agacgtccaa gaggctgcag caaatgtacc aatcgaacga ttacttgtgg aaacagatgc
    94921 cccttatctg gcaccagttc cttttagagg aaagcgaaat gaaccaggct atactcgtta
    94981 tacagtagaa aagattgctg aacttcggaa tcttccgaca gaagaagtgg ctgcccaaac
    95041 atggacaaat gcgcaccgat tatttggtct aagcgaacat ggataagatg aagatccaag
    95101 agattatagt cgttgaagga aaagacgata caagaaggct gcgggaagta gttgatgcag
    95161 atacgataga aacaataggg tctgcaatca atgaagagat cctgatgcaa attgaacatg
    95221 cccaagagac tcgtggagtg atcgttttta ccgatcctga tttttcagga gaaaaaataa
    95281 gaaaaatcat tatggaagct gttcctcagg caaaacatgc ttttttgccg cgcacacaag
    95341 ctaaaccaaa gaaaaaggga agccttggtg tcgagcatgc aagtgatgct gctattttag
    95401 aagcattgaa aaaggtcgtg acgccagaca tttcccaaac ggctgtttct gaaatcacta
    95461 gacaagacct tttagactat ggtttaatag ctggggcaca agcaaaagaa aaacgagaaa
    95521 aactaggtga cgagttgcgc atcggttaca cgaacggcaa acaattggaa aaacgtttga
    95581 agatgtttcg tattacgccg aaagaactcg cccaagcaat gaaaatagtg gaggaacaac
    95641 atgagtgaat atcgtgaaat tgcgacaccc tctagaacaa aagagatttt attgaaacat
    95701 ggtttttcat ttaaaaaaag tttaggacaa aattttctga ctgaaccaaa tattttaagg
    95761 aaaatcgtag aaactgcgca aatagatgaa catacgaacg tgatcgaagt tggaccagga
    95821 atcggtgcat tgacggaaca attagccaag catgcaaaac aagtcgtagc atttgagatc
    95881 gatgatcgtt tgatccctgt attggctgat acgatgcaac cctatgacaa tgtgactatt
    95941 gtacatcaag atattttaaa gaccgatttg tcaacagctg ttagagaaac atttcatgag
    96001 gagcttccgt taaaagtcgt agcgaattta ccttactata ttacgacacc gatcatgatg
    96061 cattttcttg aatcagattt ggttgtggat gaactagtcg tcatgatgca aaaagaagta
    96121 gctgatcgta tctctgctga accaggaacg aaagcttatg gttcattatc gattgctgtt
    96181 caatattata tggaagccag tttagcattc atcgtaccaa aaacagtatt tgtccctcag
    96241 ccaaatgtag attcagcgat tttgaaactg acaagaagag atataccggc agtcgaagtg
    96301 acagacgaaa aagcattttt ccgattgaca aaagcggcat ttcagcaaag aagaaaaacg
    96361 ctttggaata acttgcagca ttcgtatggc aaagatgacc agacaaaagc atggttagca
    96421 aaaagcttgg aaacagctgg aatcgatcca aaacgtcgtg gggagacttt gtcattacaa
    96481 gaattcgccg cattaagcaa tgcgatgtca gaaaatatgc agtaaaaaaa gaggttgtga
    96541 cagaagttgt gaaaaagctg tcctgcatca agtaataaga acagccaaac aaaaatagtt
    96601 cctcatgttt ttcgtttgtt tgggcttatt accgcagatg caagcttttg aacaccgttt
    96661 aagaaagagg ttgtgggcct gccgtttaac tctaagtcac aaggaacaat ttcaaaaaac
    96721 agcttctcat gtttttgagt tagttggtct tattacttga tgcaagcttt tgaccactat
    96781 tatgccgaac aaggagatgt gacacaaatt ttgtcacatc tcctattttt gtttcttgat
    96841 caaaaaattc ttatacttga tactcacact cattttgtat ggatttagaa aagaatatgt
    96901 gtcttgacag ttattagtaa gtgagttata ctaagtcgac atttatgtgt caagacatat
    96961 taggagagag aaaaaatgag aaaaaattca gttcgaaaac taacgatttc tgctttattg
    97021 attgggatgg gggtcattat cccaatggtc atgcctaaaa tcatgattcc accagcttcc
    97081 tttactttgg cgtctcatgt gccattattt attgcgatgt tttttacacc aggagttgca
    97141 gtggctgttg cgctaggtac gacatttggt ttctttttaa caacgccggt tatcatcgca
    97201 ttgcgagcat tgtcacatct tgtgtttgcg ttgattgggg cttggtactt gcaaaagcat
    97261 ccgagtatcg ttttaaaaaa tggacagttt acttttgcta attggcgttt ccaagggttc
    97321 aattttgtga tcggtgtgat tcattcttta gcagaaatgc tagtagtcag catcttttac
    97381 tttattggta atatgcctga aacatattat tctcaaggat atttttatac agtattcatc
    97441 ttgatgggga ttggtgggct tatccacagt ttagttgatt ataatattgc ttattttata
    97501 gcaggaacac tcagcaaata ttttgatatc cccgtattta cggcagcaaa aaaagaaaat
    97561 cggaaagagt cgattcaagg gtacgcgaag aaaacgacat attagacatg atctctcaaa
    97621 aaaaaaactc tcatctagta atggataata aatcctctaa gatgagagtt ttttgtccta
    97681 aaaagagctg caccaacatc ttctggcaca gctctaacag ggggcaattt atggaagttt
    97741 gatgacttgt tctgtttctt tatcaaagaa gtggcctttg ctgatgttga aggcaaggtc
    97801 gactatttcg cctggtttat ggaaatctct tgcatctact tttgagatga actcagtaga
    97861 accagttttt gtgtaaagca tcgtttcagc tccaagtaat tcggaaacga caacttctga
    97921 tttcactacg gcttcaggtg aagcttcaag ggctacttgt tcactgtgga tgtcttctgg
    97981 acgaataccg aagataactt cttttccttc ataacctttt tcaactaata ctttgttttt
    98041 tccttcagga atacgaagct taagcccatg tccatctgtg ataacaccat ttttcaatgt
    98101 cacattaaag aagttcatgg caggagatcc aataaagccg gcaacgaaca tattgacggg
    98161 tgtatcataa acttctttcg gtgtaccgat ttgttggata aatccgtctt tcatgataac
    98221 gattcggtca gccatagtca ttgcttctgt ctgatcgtga gtaacataga tggtcgttgt
    98281 ttcaagacgc tggtgaagtt tggcaatctc agcacgcatg gctacacgta atttagcatc
    98341 taaatttgat aatggctcat ccattaagaa gacttttgca tcccgaacga ttgcccgtcc
    98401 caatgccaca cgttggcgtt gtccaccaga taaagcagct ggttttcgtt tcaagtattc
    98461 tgtcagacct aagatctctg ctgcattgtc cacacgtttt ttgatgtctg ctttatcata
    98521 tttacgtaat ttcaagccaa aagccatatt atcaaaaaca gtcatatgag gatacaatgc
    98581 gtagttttgg aaaaccatgg caatatcacg gtctttaggt gccacgtcat tcatgacttt
    98641 tccgccgata tttagttctc cttcagagat atcttccagt cccgcgatca ttcgcaaagt
    98701 agttgacttt ccacaaccgg aaggaccaac aaaaacgata aattcacggt ctttgattga
    98761 tagattaaaa tcagttacag aataattttc tgcattgtca tattttttat atacgttttt
    98821 cagagccatt tctaccataa tacgttccac actttctttt ttagttttat taactattta
    98881 aagtataaat gaaagcgtta actaacttca atgtcatgtt gaacaagaat tttttctttt
    98941 ttttgtcaat gtgctagttt taagctttaa taaatatcca taagaaataa aaactgatac
    99001 actggagtaa ataagtatgt taacaatatc aaaaggagtg tctcttatga aaatcgcttt
    99061 gatcgctcat gaccgaaaaa aacctatgat ggtgaaatta gcaacagcgt ataaaacaat
    99121 attggaaaaa catgaacttt ttgctaccgg gacgactggg cagaggatca cggaagcaac
    99181 cggcttgccg atccatcggt ttaaatccgg accgttaggc ggggatcagc aaattggagc
    99241 catgatttcg gaggatcagt tagatttggt gatttttctt cgagacccgc tggctgcaca
    99301 gccccatgaa ccagatgtaa cagcacttat ccgtttatct gatgtctatg agattccgtt
    99361 agctacgaat atcggaacag ctgaggtgct actaagagga ctggaagccg gcttcctaga
    99421 ttttcgaaga atcgtccatg aaatagacaa gcatccactt tcattttgat ggataagcgt
    99481 atggaaaaat aacgtttaat gttcgcctat atgtagctat aaaagctaaa caaactgata
    99541 atatgcgata taatacgaac gtattggata atataaacaa taatattagt ttttcgtatt
    99601 tgcagtaaat gtgaaaatat gctatagttt ctgtgggaaa agatcccaaa aataatacag
    99661 agtagaaaat aaagcgttaa gtgctaagag gatgggatgt tgcctcttgg acgaaggacg
    99721 taatgttcgc ggttttattt tcgcattcgc tgcatgatac gatgtagcag ctcttaaagg
    99781 agatgctaaa aatgaagaaa caccggttag acgcacgtat gattgctatt atgggcttat
    99841 tgattgcatt gatggtcact ttgtcccgac tggtagcaat cgagacccca tttattaaaa
    99901 tcagtgtcac atttattcca caagtgatca tgggcattct ttttggtcct ttttggtcag
    99961 ggataggcgc agttttagct gatttagtag gaatggccct cttctcgaaa tctgcattct
   100021 ttattggatt tacattgaat gcatttattg aaggagcaat ctacggattc tttttctatc
   100081 gaaaagagat cacttggaaa aatgccattc tggctacgct tagtgtcacg ctgatcatca
   100141 acttattttt gacaccatta tggcttgcgt tgatgtacca tgtgccattg ttcagctggg
   100201 tcgtttgggc gccccgcctg ttaaaaacag taatatggtt accgattcaa tcaattgcca
   100261 tttattacgt aggacgtagt attccttaca aaaaaatttt aagaagttta gcgatccacg
   100321 ctaaataaaa aacaagcagt cttcccatcc cagaagactg cttgttttta ttgtgctgtg
   100381 aattgtgctt gatagagccg tcggtaataa ccatcttttt gaagcagctc atcatgggtg
   100441 cccatttcga caatagctcc ctgatccatc actaatatct ggtccgcatt tttgattgtg
   100501 gacaggcgat gggcaatcac aaaactggtt tttccttcca tcattgctaa gaaggcttgt
   100561 tggatttttt tctctgtcaa tgtatcgact gagctggtag cttcatctaa gatcaacata
   100621 gggggattac tgatcatcgt tcgagcaatc gtcaacagtt ggcgttgtcc atctgatatc
   100681 tttaaccctt gaccgccaat cttagtatct aatttttccg gcaaacgttc tacaaattca
   100741 tacatataag aggcttttag ggcatcattg atttctgcgt cacttgcttc cggattccca
   100801 aaacgaagat tttctcgcaa tgtactgtca aatagccaag tatcttgtaa caccattcca
   100861 aaacttttac gtaatgtatc acgttggata gagcggatgt catggtcatc gactgtaatt
   100921 gttccttttg ttgtgtcata aaaacgcatc agcaaattaa caagtgtgga ttttccggcc
   100981 cctgtttttc ctactatagc aatggtttga cctggataag cagtaaaatt gaaatcttcg
   101041 atcaaacgct gcttggggtc ataagaaaaa gaaacatgat caaaagagac ttttcctttg
   101101 atatttttgg gttccaaggc ataggcatct ggcaaatcag gcttttcttc tggctgatcg
   101161 atcaaatcaa atgctcgttc tagaccagaa aaagcggttt gcagttgtgt cgtgattcca
   101221 gaaagttcga taaatggttt agaaaactga cttgagtaga tcgtaaagct ggaaatcaca
   101281 ccaacagtga ttgacgaacc actcttcaat gccaataggc cgccaactaa accaatcgat
   101341 aaataagcaa ggtgatctac aaaacgagaa gacgggtttg tcaaggaaga agaaaattgt
   101401 gcccgttgtc ctttttcata tagatcagca tttagcagtt caaattgctg ttgactagct
   101461 tcttcttgct gaaaagcttt cacgattttc tggttaccga ttcgttcggt cacaaagccc
   101521 gagatatccc caataatcct ttgctgtcta tcgaaatttg tttgtgaagc acgagcaacg
   101581 atccaactca caaggaaaat aattggtgta gaacaaagaa cgaccaatgt cagaagtgga
   101641 cttagacgca tcataaaaat aaacgaaaga atgatgattg ccactccaga aaataattga
   101701 ttgaaggccg cagaaattgc aatggaaata ttgtccatat catttgtaaa tcgactgacg
   101761 atatttccgt gggagttttg atcataataa cgaagtggca atcgattcag atgagcaaat
   101821 gcatcttttc ttaattttgc aacggataag taagctaacc gattgcttaa cacttggatg
   101881 agccattgac tgactacgtt gattaaaacg ataccaccga atagaataag taaatggaac
   101941 agtcgattga agcggacctg tccttctcca atcatttgat cgatactttg accaatttgt
   102001 aacgtcatca caactgttgc aatcccattg atgattccta gtatcacagc tagccaaatg
   102061 tcttttgcat aggcagtaag gtaaggaatg aatcggcgga gcgtctgcaa ggataatttt
   102121 tttactttca taactattct tcctcctgtg atgcgacgat ttcctgatat tctgctgatt
   102181 gagcaagtaa ttcttcatgg gtaccctgag cagcaatctt accttgatcc atcactaaga
   102241 tatgatgtgc ttcttgaata gagcggacac gttgggagat aataatcact gtactgccaa
   102301 gataagtctg tagcgcctta cgcaaatcca agtctgtttg ataatccaac gcacttaaag
   102361 agtcatctaa aatcagtaat gctggcttgg caatcaaagc tcttgcaatc gtcagtcgct
   102421 gtttttgtcc gccagagaaa tttttcccat tttccatgac ttttgtatct aaaccatttg
   102481 gaagctgacg gacaaattct tctgcctgag cgattttcag agcttcccaa cattcttttt
   102541 ctgtggcgtc tttcttaccc cattgaaggt tttcacgaat agtcccggta aatagtacag
   102601 aagtttgggg aacaagagca atttgctgac ggagatgatc cagctgccaa gaacgaacat
   102661 ccattccgtc cattataact gtaccggaac tgacatcata gaaacgcgga atcaattgtg
   102721 tcaaagtcgt tttcccgctt ccggttggac caatgattcc aaggactgta tttcgcttca
   102781 gctgaaatgt aatattttgg agagaaagac cagaatcagg agtataacgg aagtcaacat
   102841 ggtcaaaagc gataattgct tcagaagaaa aatcgggagt agtactgacc tcagcttcaa
   102901 gaatcgaatt ttctgtgtct agcacctctt tcacccgatt tcctgaagct tcggcacgtg
   102961 tgaagatcac gacgaggttt gaaacaacga tcagtgccaa aagcatttga ttcatataat
   103021 tgatcaaagc aagaacttgt ccttgttgca agctaccaat atttactttg atcccgccaa
   103081 ctgtcagcaa acagatgatc ccgacattca tgatcaaggt tgtagcaggt gataataggg
   103141 cagagatatt ggaaacacgt aaataattgt tcgctagatc atttgtgctt ttatcgaact
   103201 tctctgtttc tttttttgtc tgcgcaaatg cgcggatgac acgaacaccg ctaagattct
   103261 gactaacgtg ttcattgagc tgatctagtt tttcttgcac tttttggtag agaggaacgg
   103321 tttttttgat gataaaaaat aaaatgattg agaaaatagg caataatgct aagaaaaaca
   103381 gacctacttc ccagtcgatc acaaaagcca tgaccactga cccgatactt aaaaacggtg
   103441 ctctgatcaa taaacgaatg accattgcta aagctagctg aagctgattg atgtcgtttg
   103501 tcattcgggt gatcaaggta tctgttccaa aatgattcaa ctcgttgtga gagaaagtat
   103561 tgattttttt gattagctga ttacgtaact ctgtaccaaa tccttgtgaa gctactgaag
   103621 catagtattg gcaaatgata gcacaaatca gaccaatcac agacatagcg accatccata
   103681 agcccatttc aatgattttt cctcggtcat tcatttttag tccattatcg atcaaggaag
   103741 ccatcattaa aggcaggaca agttcgaaga cagcttcaag aaatttgaag aacgggccca
   103801 aaatgatttg cttacgatag tcttttgcat aacgtaataa ctgaatcata tgattcctcc
   103861 tattatttat ttgtccacaa ttgaaaaaac aagtactacc acattgtagc ttaggaaatt
   103921 tagaatgaaa agagaacaag ccttttcata aatgaaagtt ttattatgaa gaagctttag
   103981 aaattgaata gactattttt tttaaaaaaa agaaaatgag aaaacatgcc agtctcttca
   104041 ttcataggaa cgtctatttt acttaatttt tctataaatg aattctgcat aaaaaatata
   104101 tcaagtaaat gtttatagat gaaactctat ttacttcttt tttaatttgt tcttgcaatc
   104161 ttttttgcta cgtaattttt gtaaaaaagt gggttgagag aaatctaatt gattttcaaa
   104221 gaaggagtat gaaaatgaga aaaatattta ttcgtttatt gtgggtacta tcttagagga
   104281 ataaataata gtggagaaaa ctatggtttg gcgcagattc tatcaggttt gatggaacga
   104341 agacaacctc ccgacatcaa gtcaaaagct acttgagatt ttgatctgaa aataaaaaaa
   104401 gaaaacaagg taggaacatc aatgtttcta ccttgttttc gtaatcaatg ggaaaaaact
   104461 aagagtggtg tacgtaatca ataaaaagga tggtgacaac agtacctctt tactctctga
   104521 aagcatcata actcgttttt cctcattatg ccaataaatt gttgttatac cacatataag
   104581 gatttgtaat agctaaaaac agacaggaaa gttgaaatct gtgaatctta ttttgtatgg
   104641 aaggatttat agaacgcaaa aatcaagata aagatgaata aaaatcctgt ttcggctata
   104701 tattgcgtat ctacgccaat aaaacgagtt tgttctgtca tagccatata aagcaaaggc
   104761 aaaaatacaa ctacagcgag ataagatccg atgatttctc gaaaagtttt ccaggaagta
   104821 tgtttcctgt ttttatattt atccgatttc attgaatagt catagcctcc ttattctttc
   104881 atatgttgaa attccagtat aaaaactgga aggaactgta cgttttttag aataaaaatt
   104941 ataagggata agtaggctgc tgtctataat aagatatatt tttcaattct ttattaaaga
   105001 ttttattgac aaaatgaatc cgttttctat gatggaggag gggtgaataa gttgttgaag
   105061 aaggaaattt tatgttactt agagaaccag acagcctttt tcgatttaga acatatgaac
   105121 gaggtcttta cagcacaaag gttagctgat cattttgggg taaaaagaaa cacagtcagt
   105181 cattatttga accagttaaa tgatgagcaa ctactagtca aaatcaattc tcgaccagtg
   105241 atttatttcc acaaagaagc ttttgaaaaa caatttttta agttacgcac gaatttttat
   105301 ttttctatcg atgatctcaa agaggaacag ccttttttcg cgcaaccaaa agacttattc
   105361 tcttttatga tcggatacga cgccagtttg aaagaaagta tcgaacaaat caaaacagct
   105421 ctttactatc cagatggcgg attaccactt ttgattacag gcgaaagtgg cacaggtaaa
   105481 agttatttag ttaatttggt ctatcagtat tgtctgcttc atgatctgct agaagattct
   105541 gcaccattca tcacttttaa ttgtgcacaa tatgcagata atcctgaact tttgactagc
   105601 aatttgtttg gacatgttaa gggagcgtac actggtgcag aagaaaataa aaaaggggct
   105661 tttgaagcag cagatggtgg gatcttgttt ttagacgagg tacatcgctt aacaccagaa
   105721 ggtcaggaaa aactgttcac ctatcttgat caaggtgtga tttatcgtat gggagaacct
   105781 aatttgtcac gccggatcaa aacacgtctc ttttttgcta cgactgaaga gattactagt
   105841 catttcttaa caactttcat tcgaagaata cctatccgaa tcgaactacc tgcacttaat
   105901 cagcgtagtc gtaatgaacg gctagaactg atttactctt tttttctcga agaacaaaga
   105961 aaaatgggga gccctttgtc agtcagtgga ccagctttgt cacttttaac aagtcagaaa
   106021 ttatccggaa acataggaga gctgaaaaat atcgtcaaag tttcagcagc aaaagcatat
   106081 gctgaacagc gtgaacagcc tgaaatccat gtcacgatcc atcatttgca aaaagaacta
   106141 cttgcgcagc ctattactaa aaatacagca cagcaaggaa tctatattac gcaagaccag
   106201 accttagagc aattaatgga gaagcaacag cccgaacagc agcgaatcgt taaaagtttt
   106261 gagcaaatcc taattgattt caagaaaaat aactgtctgc tatattcttg cgaaggaaaa
   106321 ttaaagcaag aagtgattca attatttgat tttttgctgt ttgagaccag tagacaagaa
   106381 aaacacgagc tgctggttta ttggacacaa tctatccgag agacctttcg acaaatggaa
   106441 actgcctatc aaatcaaatt cgatggaaac agtgtctatg ccttgagtta ctatctctat
   106501 cagcgaagca ctatcaaatg gttaccggaa gaacatgata ttatccaact aatcaaagaa
   106561 ttagaacaac aagtttctca gtcttatcca tctagttatc actatgtcca acgaattctg
   106621 gaattaagta agatcaaatt agatattgaa gacacaagta tggatcggat tttactgacg
   106681 atctatctaa aaaaagcgaa atggtcaaaa gaaaaacgac tgccaaaagc gatgattgct
   106741 gctcacggtt atgcaactgc tagcagtatg gcaaatgtag taaatcgttt attacaagag
   106801 gatctatttg aatcatttga tatgccacta gatgtcacac cacagcagat tgcttcagaa
   106861 atccttgatt attgcgaaaa cagcgatgtt tcaaatggat tgatcatatt agtagacatg
   106921 ggatctctga aagaaatcca tcagtttttt aaaaaacagt tatccgtacc gcttttgatt
   106981 ttgaataatg tgacgacacc tttagcaatc acagtagggg aatgcctgca aaaaaatgta
   107041 tcattagaag agatagcaga agagactgtt cgacagatcc agccagaatg gcgactgctc
   107101 tatccagagg aaaacaaacc caaagcactc attactactt gcttcactgg aatcggtacg
   107161 gcggtccact taagtgaact gctagaaaaa agcttaccta cggcttgtca gttgaaaatc
   107221 atcccatatg aatatcagca attaaaagat aagaaaaaca gtgacccatt attttccata
   107281 tacgaagtcg taggaatgat tggcaccaca gatcctgata tcaccaatat cgactatctt
   107341 tcattagaag acctcatctc gggggaaaag atgtctgtac tagctgaatg gttggacact
   107401 actatgaatg cttcagagaa ggaaatattc aatcagcgca tcattcgtaa tttttcattg
   107461 gaaaaagtac tggattccgt gactattcta gatacagaga aggtgatggg agaaatcgat
   107521 cattttatga gagaattaga ggtgcagttg aatcgaagca tcagcaatcc caaaaaatta
   107581 gcgttgtatg tccatgtgag ctgtctcatt gaacgattga tccgacaaat gccaatcgaa
   107641 acctatcaag gattagagaa atggaagcag tgtcaaaaag aagggttatc tgctattaaa
   107701 tctgcgttta gtgtcattga agagcattat agtgtcatga tccccaattc tgagattgcc
   107761 tatatctatg atattttgag tgaagataca gagtttctct cgatagaaga agaattttga
   107821 acataagcaa gttgttgcca ctaattttgg catgcaactt gcttttttag tatgtgtaag
   107881 tgaaaagagg agatgaaaaa gtggatagag aaattatctt agcttcccat ggaaaatttg
   107941 cttcagggat attagattca ttagagctga tctatgggaa aaatcattct attactgtat
   108001 tcgattgcta tactgatgag aattttgatt tagcggaaac agtaaggcag ctttttatga
   108061 ggtacaaaga taaagaaatc attgttctga cggatctttt tggcggaagt gtcaacaacg
   108121 aattcttaca atatatcaat cgggatcatg tctatctcgt tgccggattg aatttgccac
   108181 tattgattga gctagtatct cggttggacg ctgaagtaga gacaactgtt ttgatccagc
   108241 aggtgctaac tgattcaaaa aaaatgatcc agttttgtaa cgagcggctc aatcagaaaa
   108301 tagaagaaga cgaattttag gaggaagaaa aatgattgta ttgacaagag tcgaccatcg
   108361 gttattacac ggacaagtag ctttttcatg gacacaaaca ataggcgcag actgtatttt
   108421 gattgctaat gatgatgtac ctacgaatga gatacgaaag acaacgatca aattagccaa
   108481 gccacaagga gtcaaactag tgatcaaatc aattgatgac tcgattgccg cgttgaaaag
   108541 cggggtgaca gataaatata agttattcat cgtagtggaa tcgatcgagg atgcatataa
   108601 gctggcagaa gcgtatccag aaatcaaaac catcaactta ggagggatca aggcaaaacc
   108661 tggtactcgc agcatcggaa aagcggtaaa tattttacca gaagaggagg aacgcttgaa
   108721 acgattaatt gacaaacaaa tagaagtaga aatccgtcaa gtaccagcag ataaaaaagt
   108781 ggatgtaaga gaagttttgt aagaaaggaa gaacctcaat gattgtacaa gcagtcttat
   108841 taggaattgt tgcatttgtc gcacaatcag aatatgcact agggacatcg ttgctttctc
   108901 gtccgattgt gacggggctg tttacaggaa tcgtgttagg tgatgtaaaa actgggatca
   108961 ttatgggcgc aactttagag ttagcattta tcggatcgtt ctcagtaggt gcttcgattc
   109021 cacctgatgt tgtgaccggt gggattttag ggacggcttt tgctattaca gctggagccg
   109081 gtacagaaac cgcgctttta ctaggtttgc cgattgctac gttgacattg atattgaaaa
   109141 atatttactt agggcttttg attccaatta tgaaccataa agcagacaat tatgcagaag
   109201 aaggaaatta taaaggagtc gagcatatgc acttgcttgc cggtatcggt ctttccttga
   109261 tgcttggtgt tgtggtaatg gtttcttata tggtgggaag caatacgatc ggaaatctat
   109321 taaatatgat tcctgacttc gttcaaaagg ggttgtcagt agctacaggg ttgattccag
   109381 ctcttggttt tgcgatgctt gctcgtttgc tgatcaacaa acaagttgca ccatattttt
   109441 tcttaggttt tgctatagct tcttacttag agattcctgt gaccggagta gctatttttg
   109501 gtgcgatttt agcagttgtg gtagtcaata ttatgaatgt ccgtcaacta ccacttcaaa
   109561 caactgcagg ggaggtagaa gaagatgaag aattctgaga tcaaaaacag caaaataacg
   109621 aaaaaagagc taaatcacgt attttggcgt tcttttcaaa tggagttttc ttggaattat
   109681 gaacgtcaga tgaatatggc ttatgtttat gcaatgattc cgattttgaa aaagttatat
   109741 cagtcgaaag aagaaatggc agcagctttg aaacggcatc tagagttttt taacacgacc
   109801 ccacatatcg ttacactgat tttaggaatc acggctgcaa tggaggaaga aaataaggat
   109861 gatcctgaat ttgatgtgac tgcgatcgat agtatcaaaa catctttgat gggacctctt
   109921 gcagggttag gagattcttt cttttgggga actttgcgat tgattgccac aggtgtgggt
   109981 acctctttag ccatgcaagg aaatatttta ggccctatct tgttcatttt gattttcaat
   110041 attccgcaca ttctgtttcg ctatctagca acaggttggg gatatcgctt aggaacgggt
   110101 tttttgaaaa agatccaggc aaacggtatg atggaaagtt tgacattagg cgcgtctatt
   110161 attggactga tggtcgttgg agcaatgact gccacgatga tcaccatcaa tattccttta
   110221 aaaatcggtt caggagaaaa tgctgtgact gttcaaagta tttttgatga tatcgttcca
   110281 aatatcttat gtcttggagc atttggcata gtgttttatc tattgaagaa agaagtgaaa
   110341 ccattaacga tcttgatcgg actagctttc tttggaattt ttggttcgtg gatagggatt
   110401 ttttaaaaaa ggagcagaga aaatgtttac gatgcaagat tatatctatg aagaaaagga
   110461 agtactaagt acgatcttga aaaagaatga tttttcgaca agagaacata tgaaaaaaac
   110521 agtgaattta ctgatcttag caacgggttc atcttataac gcttgtttag cagcgaagcc
   110581 agcattggaa tcttatggtg atcttactgt cgatattcaa gaaccttttt attttttcaa
   110641 ttatggaaaa ctttctcctt caatcgatac tgtgattgct gtgtcacaaa gcgggaaaag
   110701 tgcttctact gttgaagcag taaaaatgat acaaaaacaa gggttacctg ttgttgctat
   110761 cacaaatgac gtgcaaagtc cacttgcttt agaagctgca caaattattg atttaggtgc
   110821 cggggtagaa tcagtaggct tcgttacaaa aggctattct gcgactgttt tacagttact
   110881 actcttaggg ataggaattg gaataagtaa aaataaaatc agcaaaaaaa tagaacaaga
   110941 ctacatgcaa cagttgcgca aaataatcaa ccatttacca gcgattattc aaaaaacgga
   111001 agaatttttt gatggatatc aaagtttatt tcgtttagca cagcgtttcg tcaccattgg
   111061 atatggtcca aactggggaa cagctaaaga agcagagacg aaattgactg aaacaatccg
   111121 cgttccgtca caaggatttg agttagaagc ttatatgcac ggcccatacc tggaggcaga
   111181 tgcttcgcat ttgctattct ttattgaagg ggaaagtgta aataaggaac gttcgcaaaa
   111241 gttgcaaaga tatatgagtc ggtacgttgg agagactctc accattacca caaaaaaagc
   111301 aagaaacgag aaaacacttg gattagcaat agaatgtgat gaatatctgt ctgtattagc
   111361 gcttgtcgtt ccgtttcaac tattcgctta taaaaccgca gtagctaaag gtattgactt
   111421 gaacaaaaag atttttgaag actttgatac agtcttgaaa agtaaattat aagaggtgga
   111481 aatcatgctg aaattcaatg aagaagaaca aatcaaagca ataaaaggcg cactagcttt
   111541 acgtccgcaa gtagaagaaa tcatcgataa actttatgcg gaaaaatttg acgctgtcta
   111601 ttatctagga atcggtggaa cgtatgcttc ctcgatgcaa gctgtcactt atatgaatgg
   111661 gaaaagcaac ttgcctgtct ttgtacagca tgctgcagaa tattacacta ctggaaacaa
   111721 aagattaaca aaagattcta tcgttatttt gtcctctgtt accggtacaa ctcaagaagt
   111781 agtgaaagca gtagaacaaa tcaagaaagt aggagcgaca ctgattggat ttatcgataa
   111841 agcgaacagt aagttgtctc agctatgcga ttttgtggtc acttatccag ctcctggaac
   111901 agaacaaatc aaatttttta tggcagcaga tcgattgatg tatttgaatg gagaattcga
   111961 agcttattca gaatactatg aacagctcga acgttattta ccaacagggt tagtggaagc
   112021 agagaaaaaa gcagatgcat ttggcttatc atttgcagaa aaacatcgac gtgatagtat
   112081 gcattatttt attggagcag ggaatcaatg gggagctgtt tattcatatg ccatgtgtta
   112141 ctgggaagaa caaagctggc ttccatcgaa atctatccat gctgccgagt ttcttcacgg
   112201 gacgttagag atcgtagaag aaacaacccc agtcacatta tttttaggcg aagatgaaca
   112261 gagagtgtta tctgaacgtg tggctaaact tttgccaaaa atttgcagca attatacatt
   112321 gatagacaca aaagactatc cagtagaagg tatcagtgaa aaatatcgcg gacgtgtttt
   112381 gtctttctta ttgatgcatg tagtgacaca acgcatcgat gctcatgtgg agcagttgaa
   112441 ctgccatcca ttagagatac gccgctacta tcgtcagttt gattattagg atagactgga
   112501 taaaaagaat ataaaaaata aagagagcag cgataactgc tccctttatt tttttaaaat
   112561 attggcatca attacgttat aaaacacatt ttttgcatta tctacagttc aacttataat
   112621 ctgtttaatg ggacatgtgg gtgccaacca ttttttgtta tgcaatagta ctatttagtt
   112681 gttgcatgga tccgtagtaa aagtccaagt acaacgagtt gcgccagttt acatagcgtt
   112741 ttgtatccag aatgttgact aaaacaaaag ttcctatgtc aaccgtcaac agagacaatc
   112801 tgtccgttgc aggacctgac agatttagaa atgttcaatc tgtctcttat gtattttaaa
   112861 tcaatactca ctaggagaag tttcctaacc tcctaatagt aatgctggta gtaacattgt
   112921 caaaactgct tcctcttagg aacaagcaaa gcataacgag tgtaaaaata aaatgtagac
   112981 tattgtaaca tatcattgat tatttcaagt aaaaacgata aaagaagtaa acaaacactt
   113041 aaaaacaatg gaaattagtc ccaactttaa gaaatgtata ctataatgga aattatcaat
   113101 tatttatttg gaggaatatc catgaaacaa aaaatcgcag ttcttggtcc tggatcttgg
   113161 ggcactgctt tagcacaaac attggcagaa aacgggcatg atgtccgtat ttggggaaat
   113221 gtacctgaac agattgatga aatcaataag tatcatacaa atcagcattt tttacctgat
   113281 ttgacgatcc cagaatcgat tatcggatat aaagaattgg cagaagcagt ggataacgca
   113341 gatgctattt tatttgttgt tccaacaaaa gcgattcgtt cagtcgcaca ggaacttatt
   113401 ggtaaaatga atactaagcc aatcattata catgcaagta aaggactaga acaagatacg
   113461 cataaacgaa tctcagaagt tttggctgaa gaaattccag aagaaaaaag acaggcaatt
   113521 gttgtattat ctggtcctag ccatgctgag gaagtggcag tacatgatat cacaacaatt
   113581 acagctgcaa gtattgatca aaaagcagca gcctatgtac aaaaactgtt catgaatgat
   113641 tatttcagga tttatacaaa taatgatgtg attggcgtag aaactggtgc agcactgaaa
   113701 aatatcattg caattggtgc cggcgctatc catggattag gattcggaga tgatgcaaaa
   113761 gcagcaatca tgactcgagg attggcagaa atcagccgtc ttggtgtcgc gatgggtgcc
   113821 aatcctctga catttatcgg tttgagtggt gtgggggact tgatcgttac ttgtacaagt
   113881 gttcattctc gcaattggcg tgccggtaac ttgttaggac agggacataa gctggaagaa
   113941 gttctagaaa acatgggaat ggtcgttgag ggtgtggcaa cgacaaaagc agcagtagag
   114001 ctagctcaac agctaggtgt tgagatgcca attactcaaa caatctataa tgttttgtat
   114061 aatggagaag atatcaaaaa agcagcaaaa gaaatcatgt tacgtgacgg aaaaatggag
   114121 aatgaatttt ctcttcgtta aatagatgat caatagttaa tcgt
//
LOCUS       DAPBCF010000003       110573 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.003, whole genome shotgun sequence.
ACCESSION   DAPBCF010000003 DAPBCF010000000
VERSION     DAPBCF010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 110573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 110573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..110573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.003"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(620..976)
                     /locus_tag="RD508_000225"
     CDS             complement(620..976)
                     /locus_tag="RD508_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HDT7734859.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(990..1400)
                     /gene="spx"
                     /locus_tag="RD508_000226"
     CDS             complement(990..1400)
                     /gene="spx"
                     /locus_tag="RD508_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HDT7734860.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            complement(1752..3938)
                     /locus_tag="RD508_000227"
     CDS             complement(1752..3938)
                     /locus_tag="RD508_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDT7734861.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            4170..4853
                     /locus_tag="RD508_000228"
     CDS             4170..4853
                     /locus_tag="RD508_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HDT7734862.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(4934..5653)
                     /locus_tag="RD508_000229"
     CDS             complement(4934..5653)
                     /locus_tag="RD508_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDT7734863.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(5965..6171)
                     /locus_tag="RD508_000230"
     CDS             complement(5965..6171)
                     /locus_tag="RD508_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734864.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            6416..7018
                     /locus_tag="RD508_000231"
     CDS             6416..7018
                     /locus_tag="RD508_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDT7734865.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            7159..8439
                     /locus_tag="RD508_000232"
     CDS             7159..8439
                     /locus_tag="RD508_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDT7734866.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIALSAFLSALLAFCFKKTLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLVVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            8452..9180
                     /locus_tag="RD508_000233"
     CDS             8452..9180
                     /locus_tag="RD508_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7734867.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(9249..10772)
                     /locus_tag="RD508_000234"
     CDS             complement(9249..10772)
                     /locus_tag="RD508_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HDT7734868.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVASI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFITQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYIEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEALLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            11024..12205
                     /locus_tag="RD508_000235"
     CDS             11024..12205
                     /locus_tag="RD508_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7734869.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSVW
                     LVPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYQNSSFSEEDYF
                     K"
     gene            complement(12265..13893)
                     /gene="treC"
                     /locus_tag="RD508_000236"
     CDS             complement(12265..13893)
                     /gene="treC"
                     /locus_tag="RD508_000236"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDT7734870.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(14414..17125)
                     /locus_tag="RD508_000237"
     CDS             complement(14414..17125)
                     /locus_tag="RD508_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7734871.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNAKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKAAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(17135..17836)
                     /locus_tag="RD508_000238"
     CDS             complement(17135..17836)
                     /locus_tag="RD508_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7734872.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            18021..18620
                     /locus_tag="RD508_000239"
     CDS             18021..18620
                     /locus_tag="RD508_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7734873.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKGIVNNGTLSPHTAQSILSNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTNN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHVVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            18701..19714
                     /locus_tag="RD508_000240"
     CDS             18701..19714
                     /locus_tag="RD508_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDT7734874.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQISHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEESGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            19823..20740
                     /gene="rbsK"
                     /locus_tag="RD508_000241"
     CDS             19823..20740
                     /gene="rbsK"
                     /locus_tag="RD508_000241"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDT7734875.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            20768..21163
                     /gene="rbsD"
                     /locus_tag="RD508_000242"
     CDS             20768..21163
                     /gene="rbsD"
                     /locus_tag="RD508_000242"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HDT7734876.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            21163..22536
                     /locus_tag="RD508_000243"
     CDS             21163..22536
                     /locus_tag="RD508_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7734877.1"
                     /translation="METTMNPEQMVLYEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRDNMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            22893..25043
                     /locus_tag="RD508_000244"
     CDS             22893..25043
                     /locus_tag="RD508_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDT7734878.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQTADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFEPVPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNN
                     NNGSNNSNNNNNNSNNGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPN
                     TANQSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFEHLGKPYVWGAKGPN
                     TFDCSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVG
                     IYIGNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPATSGSLTGSSILDGLDGS
                     FHFSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLF
                     GIKGSYNGSSVTFNTHEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDF
                     YKPTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEA
                     NAEILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQ
                     IPETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(25095..26135)
                     /locus_tag="RD508_000245"
     CDS             complement(25095..26135)
                     /locus_tag="RD508_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDT7734879.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSLDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(26411..28213)
                     /locus_tag="RD508_000246"
     CDS             complement(26411..28213)
                     /locus_tag="RD508_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7734880.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAEKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQTTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(28227..28979)
                     /locus_tag="RD508_000247"
     CDS             complement(28227..28979)
                     /locus_tag="RD508_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7734881.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(28988..29350)
                     /locus_tag="RD508_000248"
     CDS             complement(28988..29350)
                     /locus_tag="RD508_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7734882.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(29526..30398)
                     /locus_tag="RD508_000249"
     CDS             complement(29526..30398)
                     /locus_tag="RD508_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDT7734883.1"
                     /translation="MREKRAFYINGYAGIVGLIVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(30449..30937)
                     /locus_tag="RD508_000250"
     CDS             complement(30449..30937)
                     /locus_tag="RD508_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HDT7734884.1"
                     /translation="MKAEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(31075..31866)
                     /locus_tag="RD508_000251"
     CDS             complement(31075..31866)
                     /locus_tag="RD508_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDT7734885.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADYELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(31921..32529)
                     /locus_tag="RD508_000252"
     CDS             complement(31921..32529)
                     /locus_tag="RD508_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HDT7734886.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(32522..32839)
                     /locus_tag="RD508_000253"
     CDS             complement(32522..32839)
                     /locus_tag="RD508_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7734887.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(32996..33724)
                     /locus_tag="RD508_000254"
     CDS             complement(32996..33724)
                     /locus_tag="RD508_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDT7734888.1"
                     /translation="MPTGVLINVGSVLLGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            33884..34765
                     /locus_tag="RD508_000255"
     CDS             33884..34765
                     /locus_tag="RD508_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7734889.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITDFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(35005..36045)
                     /locus_tag="RD508_000256"
     CDS             complement(35005..36045)
                     /locus_tag="RD508_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7734890.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRVIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFLQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQVNGKIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAIIRLSK"
     gene            complement(36048..36716)
                     /locus_tag="RD508_000257"
     CDS             complement(36048..36716)
                     /locus_tag="RD508_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7734891.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     HIELIITDVMMPEMDGYDLVGSLRNARFDMPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSILTIGQTKLELDTYTVVQNQHSFILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            36858..39194
                     /locus_tag="RD508_000258"
     CDS             36858..39194
                     /locus_tag="RD508_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7734892.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTDHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSD
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(39309..39710)
                     /locus_tag="RD508_000259"
     CDS             complement(39309..39710)
                     /locus_tag="RD508_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734893.1"
                     /translation="MEWMRFFDNRINYDILINKRKRILSVGGRKVKKMEESFPKAAKV
                     ENIANILKVTFENGEVKYVKSHWTEEITDDLQFGKKGRGKRKNLLALSRNMWIGTEVT
                     IEADGTVFINGKDRYTPEELWYKGKKSIPEL"
     gene            39801..41276
                     /locus_tag="RD508_000260"
     CDS             39801..41276
                     /locus_tag="RD508_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HDT7734894.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDVIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGMSAKTIFDGTVPFDMKEHFVRAKFQEVKDWEKYLK"
     gene            41323..41907
                     /locus_tag="RD508_000261"
     CDS             41323..41907
                     /locus_tag="RD508_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HDT7734895.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLNEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFGIVNEHSKRWQGD"
     gene            41909..42328
                     /locus_tag="RD508_000262"
     CDS             41909..42328
                     /locus_tag="RD508_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HDT7734896.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(42609..42893)
                     /locus_tag="RD508_000263"
     CDS             complement(42609..42893)
                     /locus_tag="RD508_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HDT7734897.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(43245..43955)
                     /locus_tag="RD508_000264"
     CDS             complement(43245..43955)
                     /locus_tag="RD508_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HDT7734898.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(43952..45424)
                     /locus_tag="RD508_000265"
     CDS             complement(43952..45424)
                     /locus_tag="RD508_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDT7734899.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLTKAGDNA"
     gene            45562..46035
                     /locus_tag="RD508_000266"
     CDS             45562..46035
                     /locus_tag="RD508_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7734900.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(46188..46739)
                     /locus_tag="RD508_000267"
     CDS             complement(46188..46739)
                     /locus_tag="RD508_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7734901.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            46844..47374
                     /locus_tag="RD508_000268"
     CDS             46844..47374
                     /locus_tag="RD508_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HDT7734902.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(47860..48303)
                     /locus_tag="RD508_000269"
     CDS             complement(47860..48303)
                     /locus_tag="RD508_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7734903.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(48319..49479)
                     /locus_tag="RD508_000270"
     CDS             complement(48319..49479)
                     /locus_tag="RD508_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7734904.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTIAEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            50355..52055
                     /locus_tag="RD508_000271"
     CDS             50355..52055
                     /locus_tag="RD508_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734905.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNTVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNIRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFNKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKHLRA
                     "
     gene            complement(52157..52990)
                     /locus_tag="RD508_000272"
     CDS             complement(52157..52990)
                     /locus_tag="RD508_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDT7734906.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLAKKTLESQVLTVSQSQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEEGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(53540..55705)
                     /locus_tag="RD508_000273"
     CDS             complement(53540..55705)
                     /locus_tag="RD508_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7734907.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTSGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNRQADS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLEVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLDTVTAGKVIGSIKM"
     gene            55965..58259
                     /locus_tag="RD508_000274"
     CDS             55965..58259
                     /locus_tag="RD508_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDT7734908.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEATITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            58252..58917
                     /gene="pgmB"
                     /locus_tag="RD508_000275"
     CDS             58252..58917
                     /gene="pgmB"
                     /locus_tag="RD508_000275"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDT7734909.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDRTFNEQLK
                     GVSREDSLSLLLAHGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            58910..59917
                     /locus_tag="RD508_000276"
     CDS             58910..59917
                     /locus_tag="RD508_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDT7734910.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEELPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRKMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            59939..60958
                     /locus_tag="RD508_000277"
     CDS             59939..60958
                     /locus_tag="RD508_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7734911.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDPVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(61239..62606)
                     /gene="nhaC"
                     /locus_tag="RD508_000278"
     CDS             complement(61239..62606)
                     /gene="nhaC"
                     /locus_tag="RD508_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDT7734912.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(62715..64136)
                     /locus_tag="RD508_000279"
     CDS             complement(62715..64136)
                     /locus_tag="RD508_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7734913.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(64379..66256)
                     /gene="tdc"
                     /locus_tag="RD508_000280"
     CDS             complement(64379..66256)
                     /gene="tdc"
                     /locus_tag="RD508_000280"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HDT7734914.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FTDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(66547..67803)
                     /locus_tag="RD508_000281"
     CDS             complement(66547..67803)
                     /locus_tag="RD508_000281"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDT7734915.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEVEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(67915..68120)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            68383..69684
                     /locus_tag="RD508_000282"
     CDS             68383..69684
                     /locus_tag="RD508_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDT7734916.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(69753..70352)
                     /locus_tag="RD508_000283"
     CDS             complement(69753..70352)
                     /locus_tag="RD508_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7734917.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            70606..71487
                     /locus_tag="RD508_000284"
     CDS             70606..71487
                     /locus_tag="RD508_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7734918.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTVVEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            71500..73110
                     /locus_tag="RD508_000285"
     CDS             71500..73110
                     /locus_tag="RD508_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HDT7734919.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRMGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(73187..73846)
                     /locus_tag="RD508_000286"
     CDS             complement(73187..73846)
                     /locus_tag="RD508_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDT7734920.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(74129..74794)
                     /locus_tag="RD508_000287"
     CDS             complement(74129..74794)
                     /locus_tag="RD508_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HDT7734921.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(74941..75546)
                     /gene="dhaL"
                     /locus_tag="RD508_000288"
     CDS             complement(74941..75546)
                     /gene="dhaL"
                     /locus_tag="RD508_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HDT7734922.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(75574..76584)
                     /gene="dhaK"
                     /locus_tag="RD508_000289"
     CDS             complement(75574..76584)
                     /gene="dhaK"
                     /locus_tag="RD508_000289"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HDT7734923.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(76559..77005)
                     /gene="dhaM"
                     /locus_tag="RD508_000290"
     CDS             complement(76559..77005)
                     /gene="dhaM"
                     /locus_tag="RD508_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HDT7734924.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            77108..77428
                     /locus_tag="RD508_000291"
     CDS             77108..77428
                     /locus_tag="RD508_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDT7734925.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(77540..78409)
                     /locus_tag="RD508_000292"
     CDS             complement(77540..78409)
                     /locus_tag="RD508_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7734926.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(78505..79808)
                     /locus_tag="RD508_000293"
                     /pseudo
     CDS             complement(78505..79808)
                     /locus_tag="RD508_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(79805..80314)
                     /locus_tag="RD508_000294"
     CDS             complement(79805..80314)
                     /locus_tag="RD508_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734927.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(80489..82624)
                     /locus_tag="RD508_000295"
     CDS             complement(80489..82624)
                     /locus_tag="RD508_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7734928.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(82707..84362)
                     /locus_tag="RD508_000296"
     CDS             complement(82707..84362)
                     /locus_tag="RD508_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7734929.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(84364..84678)
                     /locus_tag="RD508_000297"
     CDS             complement(84364..84678)
                     /locus_tag="RD508_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDT7734930.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            84848..85108
                     /locus_tag="RD508_000298"
     CDS             84848..85108
                     /locus_tag="RD508_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HDT7734931.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            85122..85436
                     /locus_tag="RD508_000299"
     CDS             85122..85436
                     /locus_tag="RD508_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HDT7734932.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(86166..86720)
                     /locus_tag="RD508_000300"
     CDS             complement(86166..86720)
                     /locus_tag="RD508_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDT7734933.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(86846..88774)
                     /locus_tag="RD508_000301"
     CDS             complement(86846..88774)
                     /locus_tag="RD508_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDT7734934.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLL
                     KEMRKRQEERRVNDENSK"
     gene            complement(89080..89796)
                     /locus_tag="RD508_000302"
     CDS             complement(89080..89796)
                     /locus_tag="RD508_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HDT7734935.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(89797..91620)
                     /gene="glpO"
                     /locus_tag="RD508_000303"
     CDS             complement(89797..91620)
                     /gene="glpO"
                     /locus_tag="RD508_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HDT7734936.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(91634..93130)
                     /gene="glpK"
                     /locus_tag="RD508_000304"
     CDS             complement(91634..93130)
                     /gene="glpK"
                     /locus_tag="RD508_000304"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDT7734937.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(93266..94726)
                     /locus_tag="RD508_000305"
     CDS             complement(93266..94726)
                     /locus_tag="RD508_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7734938.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(94716..96011)
                     /locus_tag="RD508_000306"
     CDS             complement(94716..96011)
                     /locus_tag="RD508_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7734939.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVKEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(96343..97020)
                     /locus_tag="RD508_000307"
     CDS             complement(96343..97020)
                     /locus_tag="RD508_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HDT7734940.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(97050..98141)
                     /locus_tag="RD508_000308"
     CDS             complement(97050..98141)
                     /locus_tag="RD508_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HDT7734941.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(98242..98676)
                     /locus_tag="RD508_000309"
     CDS             complement(98242..98676)
                     /locus_tag="RD508_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7734942.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(99260..100717)
                     /locus_tag="RD508_000310"
     CDS             complement(99260..100717)
                     /locus_tag="RD508_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7734943.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENL
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIEDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(100714..102609)
                     /locus_tag="RD508_000311"
     CDS             complement(100714..102609)
                     /locus_tag="RD508_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7734944.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(102667..104442)
                     /locus_tag="RD508_000312"
     CDS             complement(102667..104442)
                     /locus_tag="RD508_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDT7734945.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYLVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESSEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(104492..105988)
                     /locus_tag="RD508_000313"
     CDS             complement(104492..105988)
                     /locus_tag="RD508_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7734946.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     EIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRIWKEEDCAPVMLDGDEQYLQANTVDYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(106182..107804)
                     /locus_tag="RD508_000314"
     CDS             complement(106182..107804)
                     /locus_tag="RD508_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDT7734947.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(108254..109567)
                     /locus_tag="RD508_000315"
     CDS             complement(108254..109567)
                     /locus_tag="RD508_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDT7734948.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLLGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFMGFMWILNVK"
     gene            complement(109812..110036)
                     /locus_tag="RD508_000316"
     CDS             complement(109812..110036)
                     /locus_tag="RD508_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734949.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(110056..110478)
                     /locus_tag="RD508_000317"
     CDS             complement(110056..110478)
                     /locus_tag="RD508_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HDT7734950.1"
                     /translation="MESVYRQERKSNRKKGQTMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGVLTFNFSDPEGNYFVIGKAESSD"
BASE COUNT        32476 a        22776 c        19355 g        35966 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcgtttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa gcgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt tcaacgactc
      301 agttatctta tcatgtcatt tccaacatgt caacaactat tttatatgtt ttttaaaata
      361 ctattttatt gctttgctac ttaaaacaac agaaatgaat atatcatgta aatttacaca
      421 tgtcaatata tttttaactc tatatcccca cctagatttg aattttgacc acataaattg
      481 agcatgtctc tataaattga gcatgtctct atagtagaaa aataaagtca aaaaaagaac
      541 acataacacg cttgatgcta agtgttcgac tgttacaact gtatgaaatg ctcagtgact
      601 tgattaaaac agttaaagtc tatttattta agataagctg ttccatcaac tgctcattgt
      661 atccaataaa tagaacttca tcgataataa tcaaaggacg tctgaggaga ttggtatgtt
      721 gtgtgcataa aaaaatcagt tgtttttttc ctacacagga aaggtcaatc gcaatgttgt
      781 gaaaagcctc agaccaagtc gcaaatagct gttctgcttg cacttcttca aaactgcata
      841 attcttctgc ttcttctgta cttagatcgc gttcttctaa gtcaacaaat tgataaggca
      901 attgatggtg ttctaaccat tgtttcgcct tcagacttgt tacacagtgc gctgatccat
      961 agactttcac ttccacgaag gctccctccc tatgaattta agatgttatt gttttgtaaa
     1021 tagatcagat ttctggcaac acatcgaatt tcacgaggga caaatgaccg gatctcatct
     1081 tcattaaatc cgattagtat tcttttttca tcaatcaaaa taggtcgtct caataatgaa
     1141 ggatattctt tgaataagac gatcatttgc tttaaagtta attcgttaaa atctatgccc
     1201 agcttttcgt aaattttcga ccgagtggaa ataatatctt gaactcctcc ttcagtcgct
     1261 gccaagatct ttttgatctc actttctgtt aacggttcgg caaaaatatt cttctcttca
     1321 aattcaagtt gattcgcttg caaccatgct cttgcttttc tacaggaagt acagctaggc
     1381 gaagtatata cttttatcat tttctcactc ctttttaatt ataatccaat tctacagtaa
     1441 tttcttttaa aataccaatt attagctaat aaaatataaa aaaaaaaaaa atcaaaataa
     1501 ctgattattt acgtttgaat aatgagaatt attctatata ttctctattt tgataatagt
     1561 attctcattt ttaaaataaa taagggaggt gtgacaaaat tcttgtcaca cctccttttt
     1621 ccgaataaac tgtgttccag aaatagcttc ttcgaaaata agctgaagtt tcacaaaaat
     1681 ttgagaagca attttcgtac attccttctt ctttcttgaa actgaccact tctgtcacac
     1741 cctctcttct atcactttcc ttttttcaca cgactcccgg tttctttgat aaatctcgat
     1801 actttcaatt ttcttgaatt tttcatttga ggtacacata gatacagacg atttcttgct
     1861 ctagtcatcg caacataaaa tagtcttcgt tcttcttcta tcgtcgtcac tggttctgct
     1921 tttatttcat taaagtcgat tactttcttt tctgtcgctc cgttataagg caaacttcct
     1981 tcgttacaac caatcaaaaa gacatttcgg taactaagac ctttactttt gtgaatgctc
     2041 tggatacata gtgcatcaag ttttccttgt ctgtaagcaa tcaagcgggt ttttaattct
     2101 ttagctgtcg cttgggtttc ttgcgataag gcttggagtc ttctgaaagt agcatgctgc
     2161 tttacttctt ctcgtatcca ttcttgatca ctctggtcga tttccttagc tatacgtggc
     2221 agatgaagat agctttgaac aagcgaatag atttcttgat gctggtctgt tttacgcaac
     2281 gcttcctcaa actctcggat ttctgcagat ttcgatttta aattggggct tatcgacaaa
     2341 atataatctg caacggctat attttgatat ttaggagaaa agtattgatc gcattcactt
     2401 tttttcaggt agcagtctgc catcagctgc cggagcaatt gctggtaggc ctgatttttc
     2461 ttttgcagat tcagtgctgt ttgccaatga acaatttttt gatagaaatg ttggaaagac
     2521 ttgataccaa agataccttc atatggacta tctgcttcca gtacaaaagg aatattcgtt
     2581 ttcagcagag attggacaag ctgctgcgtt tgtgaagctg atcggtataa tatgattgat
     2641 tccttatatt tcccattttt ttgaataaat gtctgaattt gtttgattag ccactgactt
     2701 tctgctttag tatcagaaaa caaataggct tccataacac ctgcttcttt ttgtgctgga
     2761 atcatcgcct ttggtatccg atcattttta ttatagctga tcaatctatt tgctccttgg
     2821 acaatagctg cccgagaacg ataattagtt aataagaaaa gagttttggt aggatattct
     2881 ttttcaaagt tcttgatgta tgctggctct gatcctctga atccatagat actctgatca
     2941 tcatctccaa caacaatcaa cttgatcctg ttttcctttg tcatccgttt cacgatttcc
     3001 cattgaagtg gattagtatc ttgaaattca tcaatgaata gataatcata tttttggccg
     3061 atataatgct ggatctcctc attctccaaa gcgcttttca gattttggag tacatcattg
     3121 aactctagca attgctggct tcttttttgt tcttggagtt ccgtgagcaa tccatacagt
     3181 cgttctgata tcggctgtcg tgcattctta tcaatggaat catatttttc tttaactaac
     3241 tgaaccattt cttctactga aaggttcata ttctgccaat agtctaaccg agaagcaatc
     3301 gttttttctc catattgatc aaatatataa agattatatt tacgtatcag ctgttgcaaa
     3361 acagcattca ctttttgtgc agtatccttt gaaaagtctc cttgtattcc ttgcattgct
     3421 acttcaggaa attttcgaca aatttcattg tatatcctaa aaaagatact atggaatgtt
     3481 ccgatatgga cagcggtttt tctctggctg aaattatcta ctcgtttttt tagttcattt
     3541 gcagcgttcc ttgtaaaagt gatcattagt atgcgttctt cgtctacttg tttttgcgtc
     3601 atcagataaa cagcttttgc acagattgtt tgcgttttgc cgctcccagc tcctgctatg
     3661 attcgaagat gtttcttcat atcatatgtg atagctgctt tttgttcttg attgaagcga
     3721 ttataggaac gtttctccat cattttaaag aaagagctgt ttccttcact ttcttttact
     3781 tgtacttctt cctcaataag tccgggtgct tcgccataag ccgcttcata ggtagcaatg
     3841 atttcttctt gtagccgaaa gacttgttga agctttttat acttgttctc ccagcgtttc
     3901 aattcttttt gtaatcggag aatttctttt tcattcaact gattgatttc cttcccatct
     3961 ttcttctttg aatttgttta tttcaagttg gttatttaaa gttggttatt taaagttttg
     4021 ttgtctattt tttctttata ctaacagacc tttctaaaaa tgaaaatggg aagcgatatg
     4081 attttagttt tctgaaaatt tttccttttt ttcaatcgtt tatgctaaga taaggaagac
     4141 aaaaatattc ataaaaggtg atgaaaaaaa tgcagacttc ctttcacgag gggcgtacaa
     4201 taggactttt gctgacattt atcggaggag ccatggacag ttatacttat atccaatatg
     4261 gtgcttttgc ctctgctcaa actggcaata tcattctatc gatcatccaa gcatttgacg
     4321 gagaatggct aagtgttggt aaaaaagtat tgtctaccct tttctttttc ttagggattc
     4381 ttctaacaaa gtatctgatt gattatttta gaaaaaaaga aaaacatttc tggcgcttgt
     4441 ttgttctata ttatgaagca gtgatttttt tctttgttag tttgacaccc gtccatgagc
     4501 atcccgcatt agtaacgatt ttgattgctt ttactgcatc gatccagtgg gtagcttttg
     4561 ataaaatcaa cgggcgtgcc tacactaatt tatttacaac tggaaattta aaaggggtag
     4621 caacgaactt atatgattat tgtatttcta aagaaaaagc agattttgat cgatttttcc
     4681 actatctaag tgtcgttctt gcctttatcg caggagctat tgtccttgtt ttctgtcatc
     4741 atctgtttgg cgcccattcg attttgatcg tttccatttt atttttgatc atggccctca
     4801 ctcagacatt tcatttatgg caattttatc atacgaatcg gttcactatt tgatctcaat
     4861 gaatcaaaaa aactaagcaa gatgctgctc acagagaaat atctgcgagt gagcaatttg
     4921 cttagttttt atattattta gttgtaaaga ttccctttgc tttcgggtta tttgtagtgt
     4981 agcggatcga ctgggcatct gcctcttctg tcattttctt tgcccgcatc ttgatttctt
     5041 gtacgatttg ttctccacat gccggatcgg ctacgaaatc atatttgtcc ccatcgatca
     5101 ctattttggg acatatatca aactgttcat accactcttc gtatcgtcga ttgagttctt
     5161 tatagtagga atagagttca ggatcttgtt ctagctgttc atattcccgg cctctttttt
     5221 tgattctcgc taacatagtt tcaaaggata cacgaatata aaccagtaga tctggtttct
     5281 tttgtggcga aatttcttct aactccttca gcatcgtttc taaaagacct tcatactgct
     5341 ttacttctac ttcagaaaca cgccctaaat ctgcattcaa atgaaacagc atactatctt
     5401 cgtagatgga gcggtctagt acgttgtcat catggctgaa agcatctttg attgccaaaa
     5461 agcgtttgtt caaaaagaaa atctgtaata aaaaagtata cttttctgga ttagaataaa
     5521 atagcggcaa tacttcatta tcttccacgt tctcataaaa aggttttgtt tctaaatctt
     5581 gggcaagcat ttcagtcagt gtgcttttcc ctgcaccgat cgttcctgca acaatgatca
     5641 caattatcgg catccttcct gtaataaaat ctgttcttca ttttactact tcatttatag
     5701 aaataaaagc cttgacttta tctgctcctt aaatgctact tctctaaaag tagccaaaag
     5761 taactcctat tcatgaaaat aaaggctgtg acaaaagtct tgtcgcagcc cttttttcaa
     5821 ataaacagta ttctcctgcc aacacctcgg tcacaaggca atattcataa aacatgaaaa
     5881 gctgtttttt aacattattc cttgtaactc agagctaaac gggagactca caacctcttt
     5941 atgctctcaa cattttatct gtttttattc ttctattgta cttgatttgc gtacaactaa
     6001 ctgccagtgc agattatgag cggtatcatt gtcttctact gcgcatttca tgacacgtat
     6061 catcacacta ttttcataga ttttttctat ttttcctttt attggtgatt caaataaatc
     6121 agatttaaat gcatatgttt cgccgacttc aaacaattgt tcattttcca taagaatccc
     6181 tccatcacct tttataaggt cagtaatttt ttaacataaa tcactcgaaa aagcacaaac
     6241 ttgtcataaa aagtactttt cgtatcaaaa ctgtcacttt ttttggtaag gttcttggaa
     6301 aacgaagatt tttttaggaa atcatgacgg ttttgatgtc aaaaccactt tttatgaaac
     6361 aaaagacgtt ttttattttt tttagcataa aatttgtggt ggaggtacgt atgagatgaa
     6421 agataaagtt gtgaacaaat tattagaagc cttattcagc ggagacaaat cggaagaaga
     6481 tatggtgtat gtccaagtaa aatttgcctt agaagtttta ttgaataatc ttggaaaact
     6541 agcggtcgtt ctagtctttt ctctggtgac aggctcatgg gcggaaacag gaatcacctt
     6601 tctttcttat atctgcatcc gcagatatgc ttatggattg cattccgact ctgaattcgt
     6661 ttgtctgctg tggacactac tttatttatg gggcgttccc ttggtgatga aacatctgca
     6721 attgactatc tccttcccaa tgatggtctt tttgttaatc agctgctttt tgttactgct
     6781 tcgctatgga tcaagaggta cagcaatcaa tcccattgaa cccgagaaac gtcccccatt
     6841 attaaagaag gcgatcagca tgtttctaat tttttctctc attactttat ttttctcagc
     6901 ttcttacttt tctacctatt tgctacttgg gattgtttta gaaatagcta cgttgcttcc
     6961 tattacaaac tacttgatga attttggagg aatctttcat gaaaaaaaca atcattaaac
     7021 aattaactaa cttatctgac ttttttgtat ctggctgctg ctttggtatg agttctgaat
     7081 tcaaaatccc tgaaaaatta aaaaaataat acgctaattg tgctataatt tggtaaaaat
     7141 caatgggagc tgtactttat gtttttatgg tccatagcgt tgcaatattt gatttacaca
     7201 atttgtatct tattgattga ccatcacatc cgatacaaat atctgtttgc gggagtcatt
     7261 ctgatttctt gtattttgat tggatgggtc tattcgattt tagggatttt tactgctcta
     7321 attgctatag gaatgctgat gcttactttt ttcttctttt cgacttcgcg tcaacaattg
     7381 gtttacgccc ttccttttgg gttattgacg tcgcttttag gagatcactt aacaagcatc
     7441 ggcgattttt ttgttttgaa atcttcggtt attgaaccag gagattcatt gcagtatttt
     7501 cacattgcct tatccgcttt tttatctgct ttattagctt tttgttttaa aaaaacgtta
     7561 gagacttggt ttcacactgt ggaccgccgt atgatcggta cgatcgggac attgatatta
     7621 tttacatact atatcattat tttttatacc cgtttttctg gtgaaacacc tgatgtctta
     7681 gctttgaata cgagtttttt cattctatat ctgtgtgttg gcctgatcat cttggtttat
     7741 tattggaaaa tctctaataa gaaattagct gatcagttat tagagcaaca agtcaggatg
     7801 caacaggatt atatcaaaga tctagaaaaa aactatcaag acttgagaga attcaaacat
     7861 gattaccaaa atctgctttt ttctcttcac agctatattt cagaaggcga cttagaagga
     7921 ttacggtctt attatgatca aacgatatta cctacacgcc agatgatgaa cctttttccg
     7981 gccaatctaa gtatgttgga taatatgaaa gttcctgaga tccgtagttt actgtcatta
     8041 aaactcatga tggcacagga aaaagggttg gtcgtccagc ttcattttcc tgagccaatc
     8101 gaactggata cgaaacatac ggtaaacctt gtacgtatgc ttggtattat cttggacaat
     8161 gcgattgaag gagctagtgc tgcaaagaag aaaaaaatcg aattgaccat actcaagaag
     8221 aatcattccg tgatgattcg tgtgatcaat acaacaacaa atacattgcc gttaaaccag
     8281 ttgaaacaaa aagggttctc aacaaaaaca aatccaaaaa acgaaggcct tggcttgttt
     8341 atcttggatg aattgacaaa gaccaatcct tatcttttcc ttgaaacatc aattgaaaac
     8401 cagcgttttt ctcaaacgat ttatatacaa ataaaataaa ggagtaatga tatgattccc
     8461 atttatattt gtgaagacga tccaaaacaa ttagaagttt tatcaacggt gatcaaaaat
     8521 agaatcatga ttgaaaactt agacagttat gtccatattt ctacctctga tccggaagaa
     8581 cttctcaatg cagccaagat cagaacttct tcttttggta tttacttttt agatatcgaa
     8641 ctagaagaca gtgaaatgga tggtgtagcg atcggtaaat tgatccgtga attagatcct
     8701 ttaggaaaaa taatctatgt gacttcccat acggaaatgt cgatgaaaat cttaaaaagc
     8761 aacattgaac cgactgatta tatcgtcaaa gaggatcttt atgatttaaa agaaaatgtc
     8821 gagcatatcc tgagcaaaat tttcgaagat tttcaaatgt cccagatcca aaaagatatc
     8881 ttcaaaatag agtttaatga tgagatcaaa tttttaccga tcaaagacat ccaatatttt
     8941 tctacttcgc taggagcacc acataaactg gaagtccatt tgactcatgc ccaattacaa
     9001 ttctatgaga agatcaaaga aatcgagaaa atgcatcgga attttatccg ttgtcataaa
     9061 tcctatgtta tcaatacaca aaatgtgcgg tcgattaata aaaaaaccag agaagtcacg
     9121 ttggcaaacg gcgagaccat cccagcctct atccgtggat taaagaaatt gatttcataa
     9181 aaagaaccga atagtttgga ccgactaaat gaccagccga tccaaaccct tcggttcttt
     9241 tttgcctatc agtgcaaaag catttcctgt gcaatttcac gtccatccat tgtatctgga
     9301 taaaatgttg gccaattctc catttctttc agcaatgctt cttgactttc atttcctgca
     9361 tataaatgaa aatgttcgga gtcagccggt gcaatcgtgt gatcactgaa ttgaatatat
     9421 ctaaaagcgc cactttcctt atcttctgct tcgaatagat accttacgcc acggtttcct
     9481 gcctcgtagg tcaagatttc tttccctaca taacgataat ttgaacgttt cgttgttcca
     9541 tccttaaacg taaatgccat ctctttctca ctgatcttga ttgaagcaat atctgtttga
     9601 tagcccttcg tataatattc tttatattct tgtgctgtct tatcctgatt caatttttct
     9661 ttatattcaa aaacaggatc aaatgtccca tcttctatat acgtatctac tgtttgccaa
     9721 gttcctgccc aatctgaaag agagcgatct tgtacatcct cgtcttcgaa ataaccgtta
     9781 tagacgctct tttctttttt gggggtcaaa gtatcttcta acgggttttc tgtctctgtc
     9841 gtttttttca acgcttcgag gtttgcttcc atgatagaaa gatagttttc tccattttct
     9901 atttgttcat tcgtcaatcc ttccaaagga ttcaatactt ctaaagatac acctgcttca
     9961 tttgctaacg ttctggcaat actatctttg gcgttttctt caaaataaat atagttgatt
    10021 ccatgttctt taacaaagtg tttcagttca gcgattctcg ccgcagacgg ttcttcacta
    10081 gaagaaagac cagcaatcga tacttgattc aatccatatt ctaatgccag atagttgaat
    10141 gcagcatgtt gcgtgataaa agatctttgt tttgcttgct taaaggtttc ttgataaagc
    10201 tgatggagtg cttgaagttt ctcggtatag gctgctgcat tttttgtcca tacttcctgt
    10261 ttttctgggt aagcttcaat cagctgatca cgtatgcttg ctacctgctt gattgctaaa
    10321 cttggtgcta gccatacatg tgggtctagc tcgtgtgtat ggccttcttc cccgtgttca
    10381 tggtcatgat catgtccttc ttcacttccc ggaagtaaaa gcataccttc tgtcgctttt
    10441 atcgtatgga cattgccttc ttgtaatgtt ttttggattg cggggaccca tgtttccatg
    10501 ttttcatcat tataaacaaa gatatctgta tcttggatct ttgccatgtc tttagcagaa
    10561 ggttcataat cgtgggaatc agtccctgct ggaatcaata actctacttc tccttcatcc
    10621 ccgacgattg cttttgtaaa atcatacatg ggataaaagg tcgtcatcac gctcaatttt
    10681 tctttactgt cctcggcttt cccacttgcc ccgcaagcag ttaacatacc tgctaaaacc
    10741 agcatggcca atatacctat caatcgtttc atttatgaca ctcctcttct catcttcttt
    10801 catttgaatg ttccgattcg ccttttgtaa accgtaatag ttacgtttta gcaacaggat
    10861 ttaatttatc atatggttaa aataactgtc aagcgttttc ttattttaat tgatgagaaa
    10921 gtttatgtga atgattgacg atatttttgc aatcaacctc tatcattttc cttttatacc
    10981 cgcttttgtc tataatgaag ttatagataa aggaggaaaa agagtgaaaa aagaaacaga
    11041 tacaacgaat cgtttgatcc gctttttagg aggaaaaacc tcttactatg ttttaggaat
    11101 agttatctta cttgcgctga tcatttattt tttccatcag atctcgttta tattcaagcc
    11161 tgtcggaatc attatcgcta ctatcttgcc cccattattg tttgcactga tcttgtatta
    11221 tcttttggaa ccagtcatca aacgtttgag caagcacctt tcgaggaact tgtcagtcat
    11281 tatcgtttat gtgattattt tatttttatt ggggcttgga agcgtatggc ttgttccttt
    11341 tcttgaagaa caggcaaaga cattgatcag tagtttgcca gatttgtttc aagattttca
    11401 agagagtctc cgacaatttt tggagaaaac accttttgcc gattcattta atcaattttt
    11461 cgcttctatt gacgacgtga cgtctgatat agctggattt attggaaatt attgggaaag
    11521 tggcgcacaa cggatcagca acattttttc aactgttaca gctattttta ttactttatt
    11581 tactggtcca attgtcgctt ttttcctttt gagagatcct caaaaatttt atcagtcagt
    11641 tttagcgatt gtcccaccag catttcgtac agattttaaa aatttgacaa agattgctaa
    11701 tcaacaattg ggttcatttc taaaggggca aatcattgct tcatttatcc ttggagcagt
    11761 ctactgggtt tgtttcttac tgatcggatt agaatttgct agtgttttag ctatttctgc
    11821 tgggttgtta tgtatcattc catatattgg gccgtttatc gccttctttc caggtttgat
    11881 cattgcattc caagactcta cttttatggc tgtcaaattt gtcattgtct ggtttgccgt
    11941 acaacttctc cacggtgact tggtgattcc tcgagtaatg ggtgatcgtt tacagatcca
    12001 tccgattacg atcttaatcg ttttacttgt catgggtgat ctaatgggaa ttgtgggcgt
    12061 tatttttggt attcctatct atacgttagt caaattactc gttactttta ttttccgtaa
    12121 attcaaacaa cgctacaata aattttatgg cgataaagga gagtatcaaa actcttcatt
    12181 ttctgaagaa gattatttta aataaaacac aaaacgtcga tcttacgaga atagctcgta
    12241 ggaacgacgt tttgtgtttt tgttttaatt tttcagcaaa gcaattgcct ggtatggttt
    12301 tagctccaga ctttgatgaa gaacagtatc ggaataatta tcgataagaa tattggcttc
    12361 tgtgaatcct tctgggatgg cgatccttgt atctttatca tagaaatttg ttaatacaag
    12421 cagctgctgt ccttcaaatt ggcgaagaaa gccataaact tccggatgat ttgcttcata
    12481 agcatgataa tctccttgtg caacgattgg atatgttttt ctcagccgaa tcaatttctt
    12541 gtaataggac aaaatagaat cttcagaaga tagttctttt tctacattaa tctcttctag
    12601 cttgcctcca acttttaacc aaggtttccc tgtagtaaat cctgcttgtt ctgtgtctga
    12661 ccattgcatg ggtgttcgag agttatcgcg agattttgct ttgatccgac gaaacgcttc
    12721 tttttctgtg aatccttgtt caaggagtaa cttataagca ttcaaacttt ctacgtcaat
    12781 atagtcggaa atcgatgaat agtctgggtc gatcatgccg atttcttctc ccatataaat
    12841 atagggcgtc ccacggttca aatggatcat ggttgctagc atctctgctc cttgttttcg
    12901 atactgatcg atagctacaa atcgattgag cgcacgtggc tgatcatgat tattaaaaaa
    12961 tagagcattc cagccgttac cctcactcat cttttctccc catgtatgaa atagtcgctt
    13021 taattctgca aaatcaaatg gaggagtaga ccatttattc ccattttcat aatcgacttt
    13081 caaatgatgg aaattaaaga ccattgataa ttcttctcta ctaggttctg tatacaagat
    13141 acaattttcg atcgtcgtag agctcatttc accgactgtg atgatagtgg aatccgtccc
    13201 aaacgttgct tggttcaatt cttttagata cgtatgggtg attggtttgt ccgtatattc
    13261 aggtttgcca tcattttctt tattattttt caattgttcg tctttaccga taacattgat
    13321 aacatcgaaa cggaatcctt ttaccccttt ttccatccaa aaacgaacaa ctttgaatag
    13381 ttcctctctt actgcttggt tccgccagtt caagtcagct tgtgtccgat catataagtg
    13441 caaataatat ttccccgtat ctccaaatgg cgaccaagca cttccaccaa attttgatac
    13501 ccaatccgtt ggctcttctc ttaaaatgaa gaagtcctga taatgctggt cccctgctag
    13561 tgcttttttg aaccattcat gttctgtcga aacgtgattc agcaccatat cgagcatgat
    13621 ttctatccgg tatttctttg cttcggctat tagctgttcg aattcctcca tcgtaccaaa
    13681 gataggatcg atggctgtgt aatcagagat atcataaccg ttgtcttttt gagggcttgg
    13741 ataaataggg tttagccaaa tcatgtcgat gcctagatca ttcagatacg ggagtttttc
    13801 tttgattcct tttaaatctc caattccatc accattactg tctttgtaag atttgggata
    13861 gatttggtaa atgactttgt ctttaaatgt catggatatt tacctccatt caactgattt
    13921 attacctacc aaaacttata tatacaagtt atcatttatt attataactg aaccgaaagc
    13981 gtttgtaaaa tttatcttta tacattctaa gaggtctgtt gcccaataaa aaacaagaga
    14041 tcagacatgt atttgtctat cctcttgttt aaaatagcaa aatattcttg tttcttctat
    14101 aaatggtgct caaaagcttt tatctacggc aatcagtctt ctcaaatgta aaacatgagg
    14161 agctaatttt atttgagtat tctttttgct cgatgcagga cagctttttc acaacctctg
    14221 attcacggtg ttcaattagc agctgaccct cgttattagc tcaaaacgct gatttcacaa
    14281 cctcttcctt aagcggtgtt taaaagcttg catctgcggt aatacgccca atcaaacgaa
    14341 aaatatgaga agctattttt gtttggctgt tcttattact tgatgcagga cagctttttc
    14401 acaacctctg tttttattca ttcgatttca acgcatcaat catatcgata tgctttaatt
    14461 tgaaatgggt aacgatcatc acaataaccg tgaatacgat agttaatcct gctgataaga
    14521 cataagccca ccatgtgatc actaatggaa agatgacatt ctccatagac gcttgttgca
    14581 agatgaagtc agtcaatata tatcctacac caaatcctcc gatgattcct aaaagagtaa
    14641 agatgatatt ttctcgaaca atgtacatcg tgacttcttt atcaaaaaat ccaaggactt
    14701 ttattgtaga taattcgcgt acacgctcgg aaatattgat attagttaga ttatacaaga
    14761 cgataaaagc cagcagtcct gataatacga caaagattaa gacaaccgag tctaagttcg
    14821 ccattgattc ttcttgcgtt tcgatttgtt tggacatgaa agacgtattt gtcacagcgt
    14881 ctgtggcaag cagtttctcg gaaagcattt cttcttcttt tgttgtcatc ttatctgtac
    14941 gcagcaaaaa tgcattatcc atcatcgatt gatcagtaac tgaagcataa tattcagggg
    15001 acatataaat aaagctacct aaatagtttt tcacgatttc ttttacttcg actttccatt
    15061 ctttttgatc ttcatcataa agcgaaatat gatctcctgt agataagtca aatagttctg
    15121 ctgctttttg cgtaatagcg attcctgttt taggcaagga gcgtgggttc tcttcaagat
    15181 cagttaaatg gataaaacga tccaaatcag ctgttttact tggtacgatc actgtcagac
    15241 tttgcgaagc atgtcctttt tttctcaatt ctacggtttg agtatgaata gctaggatct
    15301 catttacttt ttcttgcttc tgcagcatat ccgctgcttt ttgacgacta tcttccgtgg
    15361 atgaatccaa tgtaacgatt gcttgatagt caatgatcgg tccaaattgt ttggctgaga
    15421 cagaacttag agaatctttc aatcccacgc ctgcaaccat cagcccggca catccagcaa
    15481 ttccgataat cgccataagc attcttgact tatatcggaa gagatttcgg taactgattt
    15541 tttgattaaa gctaaggcgt gaccacagcg gagtgatgta ttcaagaaaa atgcgtttcc
    15601 ctggcttcgg tgctttcggt tgaagcaatg cagcaggccg ttctcttaaa tctttgaata
    15661 aaacgatcat tgcagcgcca aatgcggcaa tgaagaatgc ggcagctgct tgtaaaatcg
    15721 gcggccagtc ataaaaaata agcgcactcc caatatcata ccgctcgtta gacagctcaa
    15781 aaatgatcct tggcaaaaga ttcgttccta atatcgttcc taaaacaatg cctatccctg
    15841 aggctagact tgcatagatt gcatattttt ttgcgatttc aactttcgta taacctaacg
    15901 cctttaatgt cccgatttcc ctgcggtttt cttctaccat acgtgtcatt gtcgtaaagg
    15961 tgatcaatgc agcaataaag aaaaagaaaa caggaaaaac attggcaatc gcagcgatac
    16021 gatcagacag atcaccaaat tcttgaaaac cgacattttc tgaacgttca ttgtataggt
    16081 atgatggttt agttaaattt tcaatttttt ctgcatttcg attcaattct tcctctgcag
    16141 aggccagttc acgttctttc tcaactaatt gcctttcttg ttcagcaagt tgagcttctt
    16201 gttgagataa tgtttgaaca gcgattgttc gttgcgcttc aggaagctgc tggatagttg
    16261 ctgactgttg cgctaactgt tttttagcat cttctaaccg tgttcttgct tgcgttgttt
    16321 gtgctttgcc atccgctatt ttttgctgtg ccggttctaa ttcttcgttg gccgattttt
    16381 tcagctcttc taagcgttct tcgggtcgat cttgtaaata cttttctgcc ttttcttgat
    16441 tttgctccat tttatctttg taagctttgc tgtacgtatt caaattcttt gcgtttgtaa
    16501 aatcaagata taagacagaa taaatatctg ttttaaaaac ggattcaggt aaatagacaa
    16561 aataatcgac gctaccattt ccgacgttcg cgtatcctct ctccaaattg ttgatgaaca
    16621 atggagaacg gacaaagccc gtgatggtat actctttttc tttcaattca tctgaatcaa
    16681 tctgataaat atcaccgatt ttataccctt catcttccgc tttttcatcc aatacaagct
    16741 ggtttggttt ttccgggagt tttccatcag ttaattgtag cttgttctgc ttgttatttt
    16801 tgttataaga aaatatttga atcacttcgt ttttgccagt attggaataa tagatctgtt
    16861 ttcctgtttc tacttttgca tctgggatct tttctgcttg agcaatatct ttttgtgtca
    16921 agccaccagt agaaacgatt tgcaaatcag aaagtcctgc tgtaccaaca tagtgatcca
    16981 tcgttttttg catgacaggt ccagcagttt tgacacctac aaataaaagt gttcctagca
    17041 tgacaataag gatgattgca atgaatcgtc ctttagattg ccgaatttcg cgaaaacctg
    17101 ctttaagata tgttcttgtt ttcataaaat ccccctacca tacaatctca tcaatggatg
    17161 aaggatgatc atttaattca acagacctta ctttagcatc attaatgtga atgactctat
    17221 cagcgatggg cgctaaagca gaattatgtg taatgatcaa aacggtattg ccgtgttgtc
    17281 tgctagcgtt ttgcaataat ttcaatactt gcttgcccgt ttcaaaatcc agcgcgcctg
    17341 tcggttcatc acataaaaga agtttgggat ttttagctag tgcacgagca attgaaaccc
    17401 tctgctgttc gcctcctgat aattgggacg gaaagttatt caatcgatga gctaggccca
    17461 cttgcctcaa tacctctaca ggatcaagcg catcaggaga aacttccgtt gccaattcca
    17521 cattttcttt tgctgttaga ttaggaacga gattgtagaa ttggaaaacg aaccctacat
    17581 ctgttcgtcg gtaagcagta agctgtttat ctgaaaattg cgcaatatct gtgtcatcaa
    17641 taatgatctg accttcatca ggtgtatcca tcccacctaa aatattaaga atcgttgact
    17701 ttcctgctcc acttggacca agtataatca ctaattcgcc tttttcaatt gaaaaagaaa
    17761 tatcgtcatt tgctgtaatg gtcgtttctc ccattttgta tcgtttgtat tcatttttta
    17821 cttcgacata cttcactctg attcctccat tttcacgata tttctcgcta tatctatgca
    17881 tagaatgcgt tttctcacac ttatttattt taccactgaa tttctctaga ctaaagaaag
    17941 gaatccttta tttagttgac aaataaacga tttatgattt acttacataa aaaacattgt
    18001 tatttgaaag aaggaacatc atgaatgatt taaaggaaaa tatgattttt gatttatcaa
    18061 aaactgcttt tgtcgcgatc gacatgcaaa aagggatcgt aaataacggt acactctctc
    18121 cacacactgc acaatctatt ctgtcaaaca atgatttgtt agtaagaaca ttgaaacgta
    18181 ccgctgcctt gaaagtttta gtgaacgtag acatctccac tttcccttat ttgagtcaac
    18241 aaactgatat gggtggaatg actgcttctg tacctccaga attcactgac ttgttgttga
    18301 aggattcctt gaaagataca aacaatatgt tgactatcac aaaatacaat ccaagtgcct
    18361 tttttggtac ttctcttgat cttcaacttc gccggcgtgg aatcgaaact atcattttaa
    18421 gcggtgtagc gacaacaaac ggtgtatatg ctactgcatt agatgccttc caacatgggt
    18481 atcatgtcgt acttgctgaa gatgcttgca gtgatcgtga caaagaatcc catcaattgt
    18541 tcataaaaaa gatatttccg aaaactgcac gagtacgctc aacgaaacaa ataatcgaag
    18601 ctatccaaca aagcaaataa gtactggcac acgtgatttt catttacttc tttttgattt
    18661 catgggaaaa taaccacagg atttagatag gagtatgaac atggtgaaaa aaaagatcac
    18721 aatcaaagaa gtcgctaaac tttccggcgt ttcaatcaca actgtctcct tgatattaaa
    18781 tggaaatacg gagaaattca gtccgaaaac tgttcagaaa gttttagctg ccaaagaaga
    18841 attaggctat cagcctgact attttgctag acaaatgatt accaaggaaa cgaaaacaat
    18901 tggtgtactc gttcctgata tcacgaatcc attcttcagt acactgatgc gaggaattga
    18961 ggatatcttg tataagcaga atttcgtcac gatattatgt aatgctgatt ctgatcatca
    19021 aaaagaaatc gaatatctag ccgagctcac acgtcgaggt gtggatggat tcattatcgc
    19081 gacttctgct gtctctacag atgcaatcaa cgaaaatttg aaaaaacaag gccggccctt
    19141 cattgttttg gatcagaaaa aatctgaagg atttagtgat gccgtacgaa cagacgattt
    19201 tcgcggtggt tacctagcgg gcatgcactt gcttagtcta ggtcatcaaa cgatcgccct
    19261 tgtctatcct gaaaatccgc cggaaaatgt ccacgctcgg attgaggggt ttaaatctgc
    19321 tcttgatgtt taccaaatct ctcacgacca actgatcctc ttacctacac agttctcaaa
    19381 acaaggtggc taccaaatca cagcagaact tcttgattct gctgcaactg gtgtgtttgc
    19441 tttaaatgat gaattagctt ttggattata tcgcggatta gaggaatctg gaaaaagcat
    19501 ccctgaagac tacagcatta ttggctatga taatatagat atgtgcgagt atatcaagcc
    19561 gaaactgaca acgatcgcac aaccgatctt cgaattggga caaacatctg ccaaattatt
    19621 gttagatcgg atccaattcc cagaaaaaga atgggaagaa aaaagattac ctgtacgatt
    19681 agaaaaaaga ttttcaactg cacccttgaa atagctttca aggtgtgcta tatttttatc
    19741 gaactattaa aacgttttac taaaacgttt taaaaaataa tttttcccat caaaataaat
    19801 gagatagttg gaggtttgta aaatgaacac ggttacagta attggaagta ttaatatgga
    19861 cactaccctt cgtttaacca acatgcccaa gccaggcgaa acgatgcatg cgcatgagat
    19921 ttttcacgct ggcggaggta aaggcgccaa ccaagcagtg gcagccaaac gttcaggcgc
    19981 acggacatct tttattggag gcgttggggc tgacagcgaa ggacaacagt tattagatct
    20041 actgacaaaa gaaaacatcg atacatctgg gatagctgaa atccaaggcg ccacaaccgg
    20101 acaagcaatg attatggtag acgcagcagg agaaaatagt atcttgatcc atgcaggggc
    20161 aaataatgct ttccatgaac aagaagtcct aaaaaacaag caactgatta caaacagtga
    20221 ctttattatt gctcagtttg aaagtagctt agatgcgacg atcctagctt tttctattgc
    20281 aaaagacgca ggaaaaacaa cgatcctgaa tcctgcacca gctcgtgaaa cgattcctac
    20341 tgaactactt gaaaagacag atatcattat accaaatgaa acagaaacag aaatcattac
    20401 aggaatcaga gtgacagatc ataacagttt ggtcgcagca gccgaaaaac tccatgaatt
    20461 aggtattgga acagtaatca ttacactagg cagtgccggc gctttctatc atacagaaaa
    20521 agaacacggt atcgtccctg cttttaaagt ggatgccgtt gacacaacag ccgcaggtga
    20581 tacatttatt ggcgcattaa gcagcacact tcagccagac cttagtaact tgaaagaagc
    20641 gatcctttat ggaaatctag cctcttctgt tgctgtgcag tcttatggtg cgcaaccttc
    20701 tatcccttac cgcgaagctt tagaacaatc agcagtctaa aattaacaat gagaggaaga
    20761 aacaaacatg aaaaaaggaa aagtaatcaa ttcagatatt tcacgagtaa tcgcacaaat
    20821 ggggcacttt gataaattaa gtatcgggga tgcaggcatg cctgtcccct ttggtactga
    20881 aaaaatagat ttggctgtct caaacggtct tccaagcttt ttatctgttt tagaaaacgt
    20941 tttagaagaa cttgaggtac aatcgattga attggcggaa gaaataaaga caatgaatcc
    21001 ggaaatattg gaaaaaatca aattattgtt accagataca ccgattagct ttatcccaca
    21061 tgaagaaatg aaaaaagagt tgaataactg tcatgcattt attcgtacag gcgaaatgac
    21121 accttacgcc aatattatat tagtgagtgg agtggtcttc taatggaaac gacaatgaat
    21181 cctgaacaga tggtactgta cgagcagatt catatgctga ttgaacagtt gggaggaaaa
    21241 gacaatattg attctgtcct tccatgtgcg actcggcttc gtatcaaatt gaaaaaacag
    21301 ccagtagcca atgcagaaaa attaaaacag caaatccctt ccattaagta tttcatttta
    21361 ctcgatagat atgcagaaat aatcatggat cagggattgg ctcctgctta caaggaattg
    21421 acgcgtcaaa tcgatcattc agctccgaaa gaaaagctaa atccgatcga aaaactattt
    21481 ggtttgatat cggaaatctt tacgccgatc attccgctgt ttgccggttc tggtatatta
    21541 aaaggtctgg ttgttttagc gactacgatt ggctggctta gtgaaacaag cggaacttat
    21601 catattttgt ctgctgcgtc gaatgccgtc ttttattttc tgccaatctt tcttgctttt
    21661 tctgccgcca aaacgtttaa agtgaatgga tatattgcgg ctgtcattgc tgcagcactg
    21721 attgaaccga atctgacctc tttactttca gacagtggca aagcagctac tgattttctg
    21781 gggattcctg tagtactgat gcagtatacg tctactgtca tgccggcgat tttaggtatt
    21841 ttcttttatt cttttgttga aaaattcctc aaaaaatata ttcgcgataa tatgcaatta
    21901 gtatttgtac ctttactttc attagttatc acggttcctt tgacgttaat ggtattcggg
    21961 cctgcgggtg tttaccttgg cgaaggttta gctgccgcaa ttacttggat gatggatatt
    22021 aacggaccga tcagcggcgc aatcatcgct ggtggttgga atattttggt aatatttggt
    22081 atccaatggg ctgtaaaccc tgtcatgatc agtaatatct ctgcttatgg gttcgaccga
    22141 atcgttccgt tgacaggagc agccaatttt ggaatggctg gtgcagcttt aggtgtattt
    22201 ctacgaagta aacgttcaaa aactcgttcg atctccggtt ctgcttttgc ttcgatttta
    22261 cttgcgggag tgaccgaacc aactgtttac ggaattgcga tcccattgaa aaaaccattt
    22321 gttgctgctt gcattggtgc agctgctggt ggagctgtaa tgggatttgc ccaagtgaaa
    22381 gcgatcgctt ttgtatttgg tagtctgacc acattgcctg cattcatttc cggtactttt
    22441 ttctggtact tagcaggact ggctgttagt ctagtcgtag caatgattac tactctcgtt
    22501 agcgggtttg atgaagacct aatgtcttat gaatagttaa tgaaaaagac tgaagtatga
    22561 gatgtttatc acatatttca gtctttttct ttttaggatc attattttta taaatttttg
    22621 tgatactttc caaactttgg tataatttac atatgcataa ccatttttat ccccacttgt
    22681 ttatccccaa acaaaggtgg tctatgcaat aaaatgaacg tcaaagaaaa acgaatgaat
    22741 gctcgttgct tatttacaaa ttgttttatt tagaatacac agacagattt atgaaaagaa
    22801 aaagcttttc gacacgatta tctgttccaa aaaatgtcta atgaatgctg aataagacag
    22861 aaaatcaatg aaaggaaaag gactagttta ttatgaaaaa taaaaaaacg atacgtttgc
    22921 tagctgctac ttggctgatt gctccgtccg ttttgtcgac caataccgta tttgccgtag
    22981 ataatcaaac agcagatcaa acagtcacaa cagatacgac tacatccagc tcagctacta
    23041 gtgaaacaac ggattctttt acagaagacc caactggaac aactaactca acaacaggat
    23101 cgaccgagcc aactgaaatt gatccggctg atccatcaga aaatgaaaag ccagccgaga
    23161 catattccct tacaattgct ccttctttga ttggtaagat ccaactgact gcttcgacag
    23221 cggattcccc tgaacagcaa cctttggata ttacggaaag tggaacggta gaaggtttat
    23281 tagcggaaac gaaggtaact tacactatta cgccagctga aggtgaacaa attgcttcag
    23341 tcgctgttaa tggtgccaaa gaagtaaatt atgatgcaaa gacctttaca gtaggtacga
    23401 acaatttatc tattactgca gaatttgaac ctgtaccgga tacttcaaca gagaaaccaa
    23461 ctgatcctag tgaagaagtc cctagtacac cagatccgga aacgccaaac aaaccagatg
    23521 tgggtaataa caacaataac aacaataata atggttcaaa taattcaaac aataataaca
    23581 ataattcgaa caacgggaat tcttcgaatc aaacaaaccc atctggatcg aataacaatg
    23641 gaaatactca gagagaacca aaccatccaa acaatggttc atcgaatggc ggaacgaaca
    23701 atgcttcatc tcgtccaaat acagcaaatc aaagcggtat agagaatcca tcttctgctt
    23761 cttctgattt tgttgtaaaa tcaccaattg atgctgtatt gcctacaaat acaacgaatg
    23821 tccaacaagc aatcgttcga gaagcattcg agcatcttgg aaaaccatat gtatggggag
    23881 ccaaaggtcc aaatactttt gactgttctg gtttgactta ttacgtatat atgaaagcaa
    23941 ccggtcatta tatcggtggc tggacaggcg aacagcaata tgcaggtacg cagattccag
    24001 taagtcaggc ccaacctggc gatctcgtct tctggggacc ttcttccggt gttactcacc
    24061 atgtaggtat ctatattggg aacggacaat ttatccatgc gccccaacca ggagataaag
    24121 ttcgagtaac ttctatttca gatttcacgc ctgattttgc tgtccgagta aacttagcag
    24181 gtttacctgc tacttcaggc tcgctaactg gttcatctat tttagatgga ttagatggct
    24241 cgttccattt cagtcaaaac caaacaactg atcagttctt gaaaaagatt gcagatgatg
    24301 cacaggaaat cgggcaaaaa gaaggaatct acgcatcagt catgatggct caagctatcc
    24361 ttgaaagtgg atctggaaac agcttattat caagcgaacc aaatcataac ctttttggta
    24421 tcaaaggatc atataatgga agcagcgtga ccttcaatac acatgaacaa gatagttccg
    24481 gacaaagcta ccaaatccgc gcacaattcc gtaaatatcc ttcttacaag gaaagtttgg
    24541 aagactatgc cgacttgatc aaaaatggac tgactggcaa tcctgatttc tacaaaccaa
    24601 cttggaagtc ggaaacaaaa gactacaaag aagcaaccaa atatttggaa ggacgttatg
    24661 ctacagatcg ccaatattca caaaaattga acgcgatcat cgaagcgtac gacctgacaa
    24721 aatatgatga accgaaaaaa gaagcagcaa caactgaaga agcaaacgcc gaaatcctca
    24781 atatgtctaa gcgattcgat gtgccaatca aatggacaac agatggcgtg ccaatcacag
    24841 gattagaatt ttcaacgata aaacgcgtca acaacgcttc ttccatcttc cgtgtcgctt
    24901 caatctggga tttgtggaac aattttacgg caagacagat accagaaaca actactcgta
    24961 cagttaaagc tgcaactgtt cctgtactaa ccttgttaag tttagacaaa tcattctggc
    25021 ttgatctgcc tttaaagaaa tagaataaat taaaaagggg atgtgacact gtcacactcc
    25081 ctttttaatt tattctattt ctttatattt attttgtatt ccgttacaaa ctcgcgtact
    25141 tgattaggtt ccagagtgac atctccaaaa ctttcaagtc gctccgctcc tggcagttct
    25201 tgagtctcaa atgtgatacc gccatgattt actaatttat tcccgcgcat ttccggtcca
    25261 tcttctccaa aatttgctgt aaaaatcacg attcctgaag catctgtttt tacttggatc
    25321 gatacttttt catctaggct tgtcaattcc gcagcattta gtaaaccaga ttgttttttc
    25381 aacaaaaatg gatgatcgat accgcccact atcattgatt ggcgaaaatc actggcaaag
    25441 acctcaccta attttttagg acgttggaag tcaaatgctg tgccacttac tgaaactact
    25501 tctcctgtag gcgttgtatc tttattgagc gtagcaaata atcggctatt caaccaaagt
    25561 atatgttcgt cgattgactg tgctggatca ccggttaaat tgaaatagac atgatttgta
    25621 ggattgaata ctgttttgcg gtcactgatc ccttggaccg tcactcgcca tgtatcatcg
    25681 ttcgtcagcg tataccgtac ttctacatct aaagttccag gaaatccgtt ttccatgtct
    25741 gggctagtct gatagaaaat aaccgatgct tcgttttcac cattgatgac tgtataatgc
    25801 cactgcttgg cttcaaagct aggtgcacca ccatgtaaac aatgaccagt gtccgggtct
    25861 gtttttactt cgaacgtttc atcatctaat ttgaatgtgc cattcgtgat ccgtccagcc
    25921 atacgtccga ttgaagcacc gatataaggg tctttttcta gatattcttt tgcttcatca
    25981 aaacctaaga tcaactctcg tttttcatta tcgattattg tttgaaaatg aacaacccgt
    26041 gccccaagat cactgacaga caaagatgtc ccattttgat tcgtgatagt aatcaagtga
    26101 tagttttcgc caaaattttg ttcattgatt tccatgttcc ttgcaccctc ttttctttca
    26161 tttgcactga ttccagtata catagaaacc gttttcttaa cagcttattc cgtgagtaac
    26221 gagaaaaaat ttactatatt ctaataaaag accgcgaaaa aaggttgtga caaaagtatt
    26281 gtcacaacct ctttttccga acaaacggtg ttcaaaagct tgcatctgcg gtaataagcc
    26341 caatcaaacg aaaaatatga ggagctattt ttgcttggct gttcttatta cttgatgcag
    26401 gacagctttt tcacaatctc tttttcaata cgattccagt atataaccat gtcgtcagta
    26461 catagtagat gaaatacaat acgaagaaga tcgtaaacgg aacccaaata tctttgtatg
    26521 gattttgcat gaatagacca aacatttgta atccgaataa gacatggact acacctaaga
    26581 ttcctggtgc taagaataac acgcctactt ctctacggat cgattgttta agcaacccgc
    26641 gtcgtgttcc tatcttttca agcatttcat aacgagcaat gtcactcttg cttcctgaca
    26701 agatcttgaa catcaaacag ctagcaagca tggtcaagaa agctaaacct aggaagaatc
    26761 ccataaattc aaaaccagag aatagaccat tatacacttc atacatttca tatttctggt
    26821 tgctgtactc tactttttgc aaagatggat tgttcatttt attttgagca acaagtgttt
    26881 cgattggttt caggtttgct tggaagtctt ttacctgaac tagctgtaaa gtggtttgtg
    26941 gcaagttcag ttgatcaaat tctgattgac tgactacctt gatttctttt tcttgctgtt
    27001 ccggcaattc atagcttcga agttcctctt gtacagtcag ttcattcatt ttttcagcag
    27061 gaactttttc tttcgtgatc ttcggcggtg ttccatcttc atgttttatc atgatcaatg
    27121 gttgagccgc aaattcactt gcattatagt aaatcgttcc cgcatcttct ttttgagtat
    27181 aagaagcaga aagtgttggt gaaagttctt tgattttttg ctgatcttct gcccgaggat
    27241 tattcatcac tagatcatat ccagaattgt tttctgtcaa gtctgcaatt tcatttttaa
    27301 aacctaatcc taccgtcaaa gcgcccagtg ccaaggcaaa cagcatagcg accattgaga
    27361 gcatttgtgt atattcacga atacgaaagt ttaactgtga caatgtgaaa ttgttcaatt
    27421 ttttcaatga aatctgttct gatttcttta gtaatgataa aaagaaaatg atcacagaat
    27481 ggaaaatgaa ataagttcct aatacgatcg taactaaggc tactcctata ccaaagactt
    27541 gataggtccc cacgtgtttc atcatatagt aaccgcagcc tagaaaagca attcccagta
    27601 ctacttcaag gaaaaacaag aatttatgct gcttgattct tgttggtgtc tgatccgcac
    27661 gaatcaatgc taaaatcggt tttttgacaa tcgaaaaagc attgacaaca gcagctaata
    27721 aaaacaaaac agcaaaaaac aaaacagtga tcaacaaccc gtgaatacta aaaggtgtaa
    27781 aatgcgaaat attgagatct aactgatcca ctaataatcg gtggacgata cttgtcaatc
    27841 ctacaccgac agctgaaccc actaaagtag ctgcgatccc tactaagaat gtttcagaaa
    27901 aaatcatctg tgcgattttt ctgccttttg ctcctagcat cataaacatt gcatagtctt
    27961 tttgccgcat cgtcatcaaa aaggaatttg catataaaat ataaacgaat gtgatgatcc
    28021 ctagtaaaac agaaccgaat cggaaaatga taactgtagc cgcaacgatc gtattacttt
    28081 tcaaaaaagc ttcgttgctt gccattgatt caaacatgta aaaaatagca gatgccataa
    28141 ctaatcctga gaataacacc aagtagtctc ttaaacggct cttgatccca gtaagtgata
    28201 atttccaaag catagtcaat ctccccctac tgttccaagt ttccaagaat agatagtatt
    28261 tctcgataga aggaatcacg gctttgatct ccacgtttca cttcttgatg gataccgcca
    28321 tccttgatga ataaaatacg ttggcaataa cttgcagaaa acggatcatg cgtcacaaga
    28381 agaatcgata catgatcttt tgtattcaat tcgtccatcg tatctaaaag atcccgggca
    28441 cttttggaat ccagcgcacc tgtaggctca tcccctaata gaatcgttgg ttgtgtgatc
    28501 aatgcacgtg cggcggcgac ccgttgtttt tgtccaccgg aaatctcaga aggatagctt
    28561 tccaaaatat gagagatgga taaacgttct gcaatttttt ggacacgttg cttgatttct
    28621 tttggtctga cgccttgtaa agaaagagga acagcgatat tttcttgtgc tgtcaagctt
    28681 tctaataaat taaagtcttg gaaaataaag ccaatctcat tcgcacgaaa atctgctagt
    28741 tgatttcctt ttaatgtggt cacatctttt tgattgattc ggatatgccc atctgttggt
    28801 ttatctaatg tggataaaat attcaaaagt gtcgatttac cagaaccaga agcgcccatg
    28861 atcccaataa attcgccttt ttctacatcg aagctgatgc cgcttaatgc ttgcgtcttt
    28921 ttctcattgt tttttccgta tacttttgtt acattctgta cttcgactat tttgttcatt
    28981 tctttcccta ccctttaatt agtttttcca gtgctgtttt cggcacgtct tttttttcga
    29041 cttcttcata cgaagtgaca cctttatttt tgttccaggt gatttttaaa tatgctcctt
    29101 tacgaagcgg tcgagtcaat tgtcccttga agtccagttc tttttcctta ccctctttcg
    29161 tatagccagg caggatatat ctatagttga ctgtttcttg tccagagtct gattttgaaa
    29221 ctgtttttgt accatctgtc gtaatttgta catagtattc ttctccaccc ataactacgt
    29281 aatctgcgat tttcacccct gcaagtacca caacgatgaa aacaagtaga ccgatcagaa
    29341 gttttttcac tttttcccct tctctcttac tttatatact gattatagaa aaaagcgaac
    29401 aattctgcct tcgaatcaac tatcattctt ctttcaattt tgtcattttc tttaaaacaa
    29461 ctaaaaaaag agttcaagac aataatccgt cctaaactcc ttcttcctat cttacaaaaa
    29521 gtatgtcact tacggtcttt catgtcgcct gtattgataa caggttgcgt tcctttgtct
    29581 gtaatgattg agacaagtaa attattgatc aattggactt tccgatcatc ggtgaaattg
    29641 atttcttgtc catcttcgat ttgctctaag gccatttgag tgattgtgac agctccttca
    29701 acaatggttt gtcgagcaga caaaatggct tttgcttgtt gacgttggag catggcacta
    29761 gcgatttctg ttgcataggc taaatggttc aagcgtgttt cgattacttc gacacctgct
    29821 actgctaaac gctcttgcag ttctttttgc aactcgtcag acactgccgt cgtgtttcct
    29881 cgaagcgtca aatcattctc attgaatgta tcatacgggt attggctagc gatatgccga
    29941 atggctgtct cactttggat ttctacaaaa tcttgataat acgctacatc gaataatgcc
    30001 tttgctgtat caacgacttt aaagactact actgctgaga tttcgatggg gtttccatcc
    30061 aaatcattga cttttaaaac agaactattg aaattccgaa ctttcaacga aacagtcatt
    30121 ttttgtgcca aaggtatcgt aaggaaaaag ccattttctc gaatcgtacc taaatattgt
    30181 ccaaaaaaca aaattacttt tgcttgatta ggactgacta cagttgccga acttaacaac
    30241 aataacgtga tcaaccaaag aaaaatactt aaaaaaagtg cccaaacttt cgcttgccac
    30301 atgcctaaat agaagaaaaa caatccaact aaagctaata cgatcaatcc gacaatccct
    30361 gcataaccat tgatataaaa tgctcttttt tctctcatgc tacttcctgc gctcctttat
    30421 ccttcaataa atatctaatg ttactttttt aatttttttt tcgaatacgc gccattacac
    30481 cttctagttc taactctttg tcttcagtga tgtaccaacc gcttgcctgt gtccctccgg
    30541 ctgcctgcgg taaataatcc aattttgttc gaacccagtg cttttcttct gtaaaatagt
    30601 cttctaccaa gacctctaga tccatccctg ctgaaagagg caaatcttcc cgaacagatt
    30661 taaagataaa tcgttccttc ttcccatcat acttcaatat tcctgtatcg ataatcggta
    30721 aagaataata atccagctct ttcttcaccg tcaataaatg tttgaaaact tcatggtaca
    30781 cttgctctaa ttggcgacct tctgaattgt tcgggtaatt aaccatcact ttttctttgt
    30841 ctggatcata gaaggtttgg cttagttgag tgatataagt atgtaatctt tccatttctg
    30901 tctttaactt ttctctttga ccttcttctg ccttcatata ctttttcacc ctgttttctt
    30961 tatagatatt ttctttctta ttttactata gttatgtgcg ttaagcgatg aaaaacagca
    31021 aagattggaa ggatctttgc tgttttttct taaaatatct agttgagtac aggatcaatc
    31081 tgtttcattg tcctcttgat ccgtcgtaat attgatcgat gtgtctttag cagtgatctt
    31141 tagctttttc tgtccttgtt ctaacaaagt atttgttatt ggctggtagt ctttttcaat
    31201 ataagattca ccagacgttt ggatagtata gccactgttt tccatctcat gcaaagataa
    31261 attaccaccg tttaggatga cttttccttc tttgctgatc aaactgtctt ctagatggaa
    31321 gttgctgttt tcacctgtga cgatcaagtt atccacattg gcctcatcta gtcgaagtga
    31381 gcctaattca tctttcgcag ttattgttcc tcctgtaaat tcattgaacg atacccagcc
    31441 atcatgtgtc ttagtattca cttttttgat tgatacttcg ttgatatcaa ttgcactatt
    31501 attcccttcg attgtcaatt cagataattc ataatctgca gggacaacaa tagtgatttg
    31561 tgcacttgtg tcttctaaac taatgattgc acctgttgat tttttgactg cattcacagt
    31621 caacacgcca tttttctcct ttatttctgg cttttctgtc ttatcataag tcgtttttat
    31681 ctcaaaatcc aatccgcgta tgaccgaaac tgtttgattt tctgcatgga tgacgatttt
    31741 gtttgcatcc ttgatttttt ttgtctcagt aaccatatcg atcaaccgag gaccattatc
    31801 ccaagtcaga ctcttttgag cgcctaatgt ataagttgca cctgctagga ggccaccagt
    31861 aagcatcaga ccaataccgg taatcaaaaa atgtttcaat ctcaatttat gtgtcctcct
    31921 tcaaacgccc gctgaatgca gatctctttt tgtaataaaa cgtcgtccca tccatttaac
    31981 aaagttcatc atgacataaa aaagcccttt tgttcctttc agcaacagtg gcgaaataaa
    32041 tactgcgctt cctgtggcga acagaccgac accgataaag aataatccac tcagaatcga
    32101 ttgtccaaac acacttattc ctgatatgat catgaatagg ccaacaccta agatactgat
    32161 acataaaaca tagatactaa aaatgagcgc tagtaaagca accaatagtc ccccaataac
    32221 caatataaac cccagtgcta gtggaatgag gacaggagaa gcaaataaac cgataatgat
    32281 taaccaaatc aggcgaattt gtctttttgg atttttcact aactcgtttt ctgcttgttc
    32341 ttcttctgaa aagtaactga tttttaattt taaggcaaac tgctttggtg taccatattc
    32401 atcaatgatc tgatctaatg tttttccaga atctaaaaaa tattcctcat aatactggat
    32461 caaatcaaaa cgatcgtctt caggaatttc ttgaagatga tccacaactt cattcaaata
    32521 ttcattcatt tgtgctctcc tccaataacc ggtctaaaga atctcgaaaa acaatccatt
    32581 catcaataat ttcttctaaa tgacgacttc ccattggtgt caacgagtaa tatcgacggt
    32641 ttctgccttc aaaaggttca tcataggtct caagatatcc ttcttttttc aatcttctca
    32701 aaaccggata tagtgtagat tcactgacag agagactttc ttgtacgatt tttgttaagg
    32761 catacccata catatcttcc ttgcttaatg ctgctaacac agtaccatca agaagaacag
    32821 ttggaatctg gatgtgcatt acgtcaccct ctattctcaa gtgtaatatt ttatttcaat
    32881 ctatattata caacatataa tatagtttca aaatcagttt gtcaaataca aaaaaactga
    32941 ctaaaagatt tgatcctttt tagtcagcaa aaaaatggct tctctttgat ttttattata
    33001 acagtggcat aatccaattt gtccacatcc agctcagtgg catgataacg atcattgcag
    33061 gtatcatgtc agctactggg aacattttca cgttgatcat tctaaaaccg gtagcgacca
    33121 tcaagaatcc gccgcaagct ttaaaatcta agatcatgtc tggtgtagtc aatggataaa
    33181 taaattttgc caataagaac aaaatataaa aaataatgaa ttggggaatt gctatcacag
    33241 aaacgacata ccctaaatta cacgcaaaaa tagctgctgt gaaaaaatca aggacagatt
    33301 tagaaatcaa aatcgtactg tctcctgtca ttccagaatc taaacttcca tagatccccg
    33361 taccacttgc acaaaataga acaatgaccg tcactaatgt actgataaat tcatcgtggg
    33421 tcataccaag cttttcacta gggaagattt tagaaatagg tacttgcatc agcgcagccc
    33481 ccttatttat cccattacct aaatgaacaa tcagaccaat cgctgttcct atcactaaag
    33541 caaaaataac agccggcata tttttcatcg gcgcaatgga atagattccc atccccatcg
    33601 aacacacacc aaaaaccatc gtcagctgtg ctttaaaatg ttcacttaat ttatttccta
    33661 ctaatccgcc aattagtccg ccaagcaaaa cggaacctac attgatcaaa actccagttg
    33721 gcatcaaaaa aactcctctc tttttctacg aagcgaaaaa aatcagaaaa atttctgtaa
    33781 ttattgcttt cgctgcaaga aagattgtaa cagacagaga agattacacc aattcatttt
    33841 ttgtgttaaa gtattcttta ttggaataag taggaggaat atgatggata tccataaatt
    33901 cgaagttttt cttgatttag ccgaaacaat gaatttcacc aaaactgctg atcgacaatt
    33961 caccacccaa ggaaatattt ctaaacagat tctttcgtta gaaacagaat tagacgtcaa
    34021 attattcgaa cgcgcccata gaaaaatcga attgaccgaa gctggaagct tattgctccc
    34081 atatgtaaaa aatgtcgtag aacaatacca tgctatgcaa gaagtgcttg aaacctatac
    34141 gaaagacaac aatctttcat taaatatctt aacgataccg acaatgatca attataaagg
    34201 tttttccaaa atcaccgact ttttgaaacg ccatcctgaa tttacagtcc agttgaaaga
    34261 agtggaaagt gtcgaattaa cttacaatga cgccaatgaa catagtgaca cgatccactt
    34321 tgctagaagt ttccaggccc cgccgagttc gattgagtgg ttgcctactg aaacagacga
    34381 ttttgtagca gttctaccta aaaatcatcc tttagctagt aaaaagaaat tggatctaag
    34441 cgaactgaaa aaggagaact ttttgctact tggccccact acgaacttgt atcaacctgt
    34501 actagatctg tgtcgcgaag ctggatttga accaaaaatc tcttataaag gagcaagaat
    34561 cgacttgatc atcaatatga ttgcaaatga catggggatt gctattgtta tggaaaaaac
    34621 agtcaagaat ctattaaaag aaaatactgt gattctccct atttctccaa caacagagag
    34681 ttatcttgca tttactcgta aagtcggtga gcattctttg gcttcagata cattttggga
    34741 gtatttaaat caagaagaaa actaagccct acattttctg tccatctatc caccccaaaa
    34801 aagagagcga cgcatgactt tcgctctctt tcttacatcg tgccattgat tcaatgacac
    34861 atctaacgtt tctcgtattt caatagaaga tcagcgattt tatgccggaa gaacattaag
    34921 agcaattcgc taatcacaaa aaaacgtcta aaaatcccta aaaaccttca ctagaatttt
    34981 taggtatttt gttctttttt cctattattt gcttaaacgt attattgctg tcgtccctac
    35041 tccttcgata ctgctataat cgatacgtcc atcatgtagt tctagaattt ttttgaccag
    35101 tgaaagccct agtccattcc cagaaatctg acggcttgta tctccttgat aaaatttttc
    35161 aaacattcga tctcgggtct cttcattcat tcctacacct gaatcggtca cttccagtac
    35221 gatctctgtg gctgtctcaa ataatttgat atgaatcttt ccattgactt gattgtactt
    35281 tatggcgtta tccatgatat tcagccacac ttggtacaaa aactcttcat tacctgtata
    35341 gtttactgca gcaagttcga tatccaattc tagctgttct ttttcccatt taggctgcaa
    35401 aaaaacgatt acttctctga tttgttcatc taatcgatac tctttctttt ccagttggat
    35461 acgctggttt tccagtttgt ttaattttaa aatgttctct gttaattgtg aaagctgcgt
    35521 gatactttcg atgacccgat ataaaaatat ttggcgttct tcgtcagaaa gatttggggc
    35581 ttgtaacaat tgaacatatc cttggattgt tgctagtggt gttttgaatt catgggatac
    35641 actggacaca aagtcattcc tcagtgtctc gatactattg agttcttgga ccataacgtt
    35701 gaaatcttta tacagttgct gtacttctgc tactttctgc tgttcatcca ttcgaatcga
    35761 aaaatctccc gttgctacca gactcatatt tgtccctagc gcactgattg gatgcaggat
    35821 acgccgccca acaaaaatcg atattcctgt acccacgacc atactgaacc ccgcaaagac
    35881 gaataacggg tataacgttg gttttccagc cgattcagca ggcgagatag aatgtcgaga
    35941 caataagaaa ataaaaccaa gaaaacacag cagtgttact aagatcgaaa taaatacgat
    36001 actagcaaaa tagatccata attgtgaaaa tagcttcttt ttcatcttta aataaccgcc
    36061 ttatagccta gtccccgtac tgtgatgatt tgaaaatctt ctgtcttttc aaaacgggtc
    36121 cttaaacgtt tgatatgtac atcgatcgtt cgttcttctg tattcgtgtc taatccccaa
    36181 atatcgtcca tcaactgctg gcgagtgaaa atcttgtttg gataagacag taatttatac
    36241 agaagcagaa attctttttg aggcagaata aaagaatgct gattttgtac cactgtataa
    36301 gtatccagct ctaattttgt ttgcccaatc gtcaagatac tgctgtaatt gatttttgaa
    36361 cgtcgaagca atgcttccac acgcaggatc atttcattga catcgatggg ttttgtcata
    36421 taatcatctg cacctaattt gaatccacgt ttcttgtcct cgaaatcagc ctttgctgta
    36481 atcatcagaa ctggcatgtc gaatctggcg ttacgtaatg atcctaccaa gtcatagcca
    36541 tccatttcag gcatcatgac atctgtaatg atcaattcta tatgtgtcgc ttctagtttt
    36601 ttcagcgcat cctctccatt cagtgcggtg atgactgaaa agcccgctcg ttccaacaca
    36661 gaacggtaaa gcaactgtaa ttgcggatca tcttctacta ctaaaatacg attcattgat
    36721 ctccctctgt tttttgaaaa atttctagat tttttcttgt agttcatctt cagttaacat
    36781 ttatttcgta tactacgatc attgttctga tatacttatt agtataccga atatttcaat
    36841 acgggagaag ggtgattatg cttcaattaa aagatataaa aaaatattat aaagtcggcg
    36901 aaaccaccac caaagcattg gatggtgtgt ctgtcgcttt cagacaaaaa gaattcgtag
    36961 cgattttagg tcctagtggt tctggtaaaa cgactatgct gaatgtgatt ggtggactag
    37021 ataattatga ttccggtgat atggtaatca acggaaagtc tactaaagac tttaaggaca
    37081 gtgactggga tgcctaccga aacaactcta tcggtttcat ttttcaaagt tacaacttga
    37141 ttggtcatct aggcattatt gaaaacgttg agcttgggat gacattaagt ggtgtttcta
    37201 aagacgaaaa acgaaaacgg gcagaagatg cattgcaccg ggtcggcttg acagatcata
    37261 tgcataaaaa gccaaatcag ttatctggtg gacaaatgca gcgagtggcc atcgctcgag
    37321 cactagccaa tgacccagat atccttttgt gcgatgaacc aaccggagcg ttagatacag
    37381 aaacaagtat ccagatcatg gaattgatcc aagagttatc gaaagaaaaa ttagtgatca
    37441 tggtcacaca taatcctgaa ctggcccatc aatacgcaga tcggatcatt gaattttctg
    37501 atggtaagat cttaacagat tcccatcctc acatcgaacg gccaaaagat gatcaattta
    37561 acttacgcag aacaaagatg agtttttgga cagcgttgaa gctttccttc aacaatatcc
    37621 gaacaaaaaa aggacgtact ttcttgacct cctttgcttc cagtattggg atcatcggaa
    37681 tcgcgatcgt tctgtccctt tcttctggat tccaaaaaca aatcgataac acgcaagctg
    37741 aaacgatggc gaaatttccg attactattt ctaaggtaac gactaaccag actcgtgacg
    37801 atgccggatt gggtgcaagc aaagcggatt atccagacag caaaacgatt actgcaaaag
    37861 tcagcgaaga agataaagca cagcacacga ataagattga tcaaacatac gtcgattacg
    37921 taacagacat cgatcctaac ttaagtaata atatcggatt tacccgtact acaggaatca
    37981 atcttttacg tgatgtaaat ggcaaagtac agcctgtcag cttctcgaat caaaatcctg
    38041 atacggaatc tctttcttta tctagtacga tgtcagcaat gacaggtgtg ggagtgtcaa
    38101 gtttccctac acagcttgac actagcaaag aaaacttttt aaaagacaat tattctttac
    38161 ttgccggaag ttatccagcc tcagcaacag atgtcgtgct gatcgtagac ggcaataata
    38221 atactaatat caacgcattg aagaatcttg gatttgatgt gaaagaagac gaaaaacttg
    38281 attttgatga tatcgttggt acaacattca aattagtaaa caacaatact tactatacaa
    38341 aacttccaac tgggaatttt atccctaata cagattatga tgcgatgtat cagaatgctt
    38401 ctgatgaatt gaagatctcg gggatcctac gcgtgaaatc ttcttctaca atgaatctct
    38461 tatctccagg aatcgcttat agcgatcaat taacgactca aatcgtcaac gaaaacaaag
    38521 aatcagaaat cgtcaaagct caaagagaca gtgatgtaaa tgtcttaact actgaaaaag
    38581 ttgacgaaaa tgccaaacaa acattgctta gttatttagg tggagacagc ttgccttcaa
    38641 gtatcatgat ttatccgaac aattttgaag acaaagaaaa gatcttggat tatctagatg
    38701 attacaataa aggcaaatca gatgaagata aaatcattta tactgattta gctggaacga
    38761 tgactgaact gactggcgga ttgatggatg ctatcactta tgtccttatt gcttttgcag
    38821 ggatctcttt agtaacaagt atgatcatga tcagtatcat tacttataca tctgtgattg
    38881 aacggacaaa agaaatcggt gtactaaaag ctttaggtgc acgtaaaaaa gacatcactc
    38941 gcgtatttga cgcagaaacg tgtattttag gtatttcttc tgggatatta ggtgtgttta
    39001 ttgcatggct agctacattc cctatcaata gcatcttata caacatgacg gatctaaaaa
    39061 atgttgctca actaaatcct gtccatgcga ttattctagt gatcgtctct actatattga
    39121 cgatgcttgg cggtcatctt cctgcacgaa tggcagcgaa aaaagacgcc gctatcgctt
    39181 tgcgtgcaga ataaggttgt gacaaccaca tttagatttg agtcataaga gcgctgaaat
    39241 agtagaaaac agcaagaaac gaggaagtaa tatgttcctt gtttcgcgct gtttttttta
    39301 attatttttt ataattctgg tatacttttc tttcctttgt accacaactc ttctggcgta
    39361 tacctgtctt ttccatttat gaatactgtt ccatctgctt caatcgttac ttcagtccca
    39421 atccacatat tacgagaaag tgcgagaaga ttttttcttt ttcctcttcc tttttttcca
    39481 aattgcaagt catcggttat ctcttctgtc caatgagatt tcacgtattt tacttctccg
    39541 ttttcaaatg taactttcaa aatattcgct atattttcca cttttgctgc tttaggaaat
    39601 gactcctcca tttttttcac tttccttcct ccaacactaa gtatgcgctt tcttttattg
    39661 ataagtatat catagtttat tctattatca aaaaaacgca tccattccat tgtagaatac
    39721 tttaccgaac aagttgaatt gttttcctct ttttcacctt ttactataga taggtaaaga
    39781 caactaagga ggaatctctc atgacagatc aaccgtatga tttaagaaaa gtcatcgaag
    39841 aactaaaaac acttccaggt caatatcacg aaacagatat tgaaatcgat cctgaagcag
    39901 aattatctgg tgtttaccgt tatatcggtg ctggcggtac agtaaaacgt ccgactcaag
    39961 aaggaccagc tatgactttc aacaatatca aaggtttccc cggcacacgt gtgaacatcg
    40021 gaacaatggc tagtcgtaaa cgtgtaggtg aaattttgca ccatgattat cgaacacttg
    40081 gtcgtttctt gaaagacgct gtagaaaatc caatcaaacc tgtgaaagta gacaaagcag
    40141 acgctccagc acaagaagtc gttcatctag ctaccgatgc agacttcgat attcgcaaca
    40201 ttttgcctgc acctacaaat actcctgaag atgctggtcc atacatcaca atgggtgtag
    40261 tcttaggatc agatccagaa aaaacaatga gcgatgtaac gatccatcgt atggttctag
    40321 aagataaaga tacgatcggt atgtacatca tgcctggcgg acgccacatt ggtcacttcc
    40381 aaaaacaatt cgaagccttg aataaaccaa tgcctatcac tatcaatatt ggtttagatc
    40441 cagcaattgc cattggcacg actttcgaac cacctaccac tccacttggc tacaatgaac
    40501 tatggtgtgc aggagctttg cgtaacgaac ctattcaaat cgttgatggt atagcagtcg
    40561 atgaagtggg tattgctcgt gctgaattca tcattgaagc agaaatcatg ccaaatgaaa
    40621 caatgcaaga agatatcaac acgaactcag gaaaagcaat gccagaattt cctggctata
    40681 ctggggatgc taatccagct gtacaagtag tgaaagtcaa agcagttact caccgaaaag
    40741 acaatccaat catgcaaaca acgattggtc ccagtgaaga acacgtatct atggccggta
    40801 ttcctacaga agcaagtatt cttgccttgg tcgataaagc tattccagga aaagtagtaa
    40861 atgtctacaa tcctcctgca ggtggtggta aattgatgac catcatgcaa atccgtaaag
    40921 aaaacgaagc ggatgaaggt attcagcgtc aagcagctat tcttgcttta tcagccttca
    40981 aagaattgaa gacagtcatt ttagtcgatg aagatgttga tattttcgac atgaacgatg
    41041 tagtttggac tttcaacact cgtttccaag gagataaaga cgtcattgtg atcccaggaa
    41101 tgagaaacca tccattggac ccatcagaat taccagaata taatcctggc tctattcgtt
    41161 tccgtgggat gagtgcaaaa actatctttg acggtacagt tcctttcgat atgaaagaac
    41221 attttgtacg tgcaaaattc caagaagtaa aagattggga aaaatatttg aaataatgaa
    41281 tgatctgcaa ctgttttgac atcataaaaa ggagtgcgga aaatggaaca attggcacaa
    41341 cggaagaaaa aaatcgtgat tggtgtaagt ggcgcttcag gcaccattta tgccatcaac
    41401 ctagtgaaga aactaaaaga atatccgatg atagaaacac acggaatcat cagtccatgg
    41461 gcaaaacaga acttaaagct ggaatccgac ttatcactaa atgaattcga aagcctgttt
    41521 gattaccatt attcaaacaa agatttaggt gctgctgtcg ccagcggatc atttttgacc
    41581 gatggaatga tcatcgtacc agcaagtatg aaaacagtcg caggtatctc tgttggttta
    41641 ggcgacaatc ttattgcacg tgctgctgat gtaacaatga aggagcaacg aaagttagtc
    41701 attgttcctc gtgaaacgcc attaaatgcc attcacttgg aaaacttgac taaattagca
    41761 cgactaggtg tgcaaatcat accaccaatt cctgcttttt ataatcagcc tcaaacgatc
    41821 caagatcttg ttaatcacca tacaatgaaa cttttggatc aatttggaat tgtaaatgag
    41881 cattcaaaac gttggcaggg tgattaatat ggaaaaagaa acgatagttg aagtaaccaa
    41941 actaggtttc acgatccaag ctgctgttaa agtaatcggt aaagacttat tgatcacttt
    42001 aacaggcgga gatacaccac atatcggaac agtcactaca ttttctcgtg atacagagat
    42061 gcaaactgta cgtttcccta gccacgatgg tcggttccat aaagacgatg tcttagccga
    42121 aaaaatagct gtgatcatca aaactgccgt tccgggaagt tgtacgatta cttccggtat
    42181 ccatgttgac catatctcca atgcacaaat caacgcctct tttccgatgt cagaagagtt
    42241 aggttacaag attttagatt ggttggaaaa aatagatttc catatcaaag aaccagttta
    42301 ttataaagat ggtgaaaaac cattatgaaa gaagaggttg tgaaatcagc gttatgacct
    42361 gagtatgaga gaaaaaaatg gaaaaatagc ttctcatatt ttgccgtttt tgagctaata
    42421 ccgagggaca gctgattgaa cgccgtttat caagaggttg tgataaagcc gcttcgtttc
    42481 gagtagtaag aaaaattttg taaacatggg tttccacatt tttgcataaa tttgacttac
    42541 taccgagaaa ctggcttttg aacaccgttt atcaagaggt tgtgacacgt cttttgtcac
    42601 aacctctttt atttttgctt cactgtaact gctacaatat caccgatttc tttaccgatg
    42661 tttttacgaa tatcttttcg tagtccaagg atgtagcaga ctgaaccatc tggatttttc
    42721 acacccatat tcacgatact gccttcgtac ggcacattgt caaaagttgc ttggacttta
    42781 actcttccag caccgaattc ttttcttata tcatacggaa aaataatata tgccccgccc
    42841 ttgccgactt cggaagcata gatttttgat tcaaaagaat aaatttccct cattttattt
    42901 ctcctatttt ttacatctag tatagcatag caaaaaaaag aaggaactgt gacaaaagtc
    42961 ttgtcgcagt tccttttttc gaataaacgg tgttctcctg ccaactcctc ggtcacaagt
    43021 cacaatattc aacaaacatg agaagctgtt ttttgaaatt gctccttgtg actcagagtt
    43081 aaacggcagg ctcacaacct cttccttaaa cggtgttcaa aagcttgcat ctacggcact
    43141 aaccccaatc agatgaaaaa tatggagtgc tatttttatc tgattgttct tactgcttga
    43201 tgcagagcag ctttttcaca acctcctaca cggtgttcaa aatattattc gccttttgct
    43261 tctttcacta attttgcgaa tgcttgttgt tggaattcag cagctaaggc tttcgtacgt
    43321 tgttcttgct ctgctttgct catttttgga ttttcagtca ttgcttttac cataccgtct
    43381 tgaacataag cttttgcttc actttccatc gtactttgct gtttcttaac taattcagct
    43441 aacttggctg cttggtccgt acttaattct acccatgtct ctgggatttt gaatgtattc
    43501 actcggctgt catattcgtg attgttatca gcaatattga accagaattt atacatgtcg
    43561 tttttgtatt cccaataagt agttttcgtc actttttcag catcgccgtc tgtcttttct
    43621 actttatttg tttcgttatc cgtaccagtt gcttttggtt tttcttgttt ttcatttgtt
    43681 cggtaaagat acactttttc ttttccattc cctaaagctt tatacaaaag catatctgct
    43741 ccttgggaat cagcactgga aacaattttt tctgtttttg tttccgttac tttttccatt
    43801 ccaaagtgat tggacaaatt agcgacgatc aaacttagtg aagcgacgaa gattagtccg
    43861 aaaatcaaag ataaaaaggt ttgccatgtt tttttagcga acacgttcgt taaagcaaaa
    43921 gcaagcaagc tgacaatcaa aactccaata atcatgcatt atcccccgct ttcgttagaa
    43981 caggttcttt tttcttcaat aaaaaggcaa taataaagcc aaggatccca aagatgatcg
    44041 ctacgataaa cgcggcatgg taacctgaca gtgtggcatt gattgcctga tctttataag
    44101 ctaatggtgt attatccaat acagatttgc ttgggatatt tgcttttgtc acattcgtca
    44161 acacactgat caaaatagct gtaccaatcg agcttgcgat ttgacggaat gtattattta
    44221 ccgctgtccc gtgactgatc aagttatttg gcaatgcatt cataccagaa gtcgttaccg
    44281 gcatcatgac catggagatc ccaaacatac ggatcgcata aaggatcacg atatataaaa
    44341 ctggagtcgt ttttgtcaag aaagcaaatg gtgcagttgc ggctgtcaaa atgaacatcc
    44401 ctgtgatggc taaacgtttc gcgccatatt tatcgaaaat cgcacccgta acaggcatca
    44461 tagcccccat gatcaatgca cccggcaaca acatcaagcc agaatggaat gctgattctc
    44521 cacgaatatt ttgaatatac aatggtacga ccatttctgc ccctaccatc gccatatttg
    44581 ttacaccagc taaaacagcg gcaatcgtga atgtagatga tttgaatacg cgaagttcca
    44641 agaatggatg ttccaaatgt aattgacgcc atgaaaacaa tgcgatgaaa atcacaccaa
    44701 caactaagaa accaattact ttcaagcttc cccagccgtc atctcctaca ctagaaaatc
    44761 cgtaaagcaa actaccgaat ccaatcgttg ataaaatagc ggataaaata tcaatgctag
    44821 gatttgacaa tggaataacg ctcttcatta ggaagaatgc taaaaccaag acaagaacaa
    44881 cgattggcag taccatacca aacaagtcac gccaatggta gttatcaatg atataaccag
    44941 ataatgtagg gcctaaagca ggagcaagtc caataacgat ccctgacatc cccattgctg
    45001 atcctctttt ttctggcggg aaaatagata gcatgatatt ttgcaataat ggcatcgata
    45061 ctcccacacc gcaagcttgg atcaagcgac cgattagtaa tgtactaaaa ttaggtgctg
    45121 taaagcaagt aatcgttccg atcaaaaaga tcgtcatggc agaaagatat aaatttcttg
    45181 aactgaattt attgatcagc catgctgtta ttgggatcat aatcccgttg actagcaaga
    45241 aaccagtcgt taaccattgc acatcagacg ctgaaatatc gaaagctttc atcaatgtag
    45301 gaaaagctgt cgtcaataag gtctgattca aaacggtaca aaatgtacca attaataaga
    45361 caacaactaa aagtgtccga ttatatggtt ttccgtaaat atctacgggt tggttgttac
    45421 tcatatttct ccttctttct gaattttttc tgaaactact agaatacttt agtcctaaat
    45481 tcgctatttg tcaacctact tgacacataa gttaatacgg atataattaa gggaagcaag
    45541 aggacaaaag gagtgacaaa aatggttggg gcttccctta aacgtttgtt ggaaaatgat
    45601 caattggttg ttggcatcag tgaattaagt gatatcgtag gtgtgtctcc acgtcaatta
    45661 aggtattggg aacaaaaggg attcattcgt tcgatcgaag ctgatgcgaa ttgtcctaga
    45721 aaatatcgtt tacctacagt cataaaagta gaactgatca aaaaatattt agatgacgga
    45781 tttactttgt caaaagctgc agaaaaggca gaaatccgcc aaaagaaaat gcaccatgtc
    45841 cgtaaagttt tttcaaaagc aatcaaagat atcgaattga tcgacgaacg ctatacgatt
    45901 ttacaaatcg gtaacttcaa agaagagaat gctaagatgt acatcattca tgacaacgag
    45961 acagacgaat taacttacaa gctccttcct gtcgatgaaa aagctgacta cgaacagctg
    46021 ttaaaagaac tctaaacgcc actaatctcc taagtaccaa gctttttaat aagtagatgc
    46081 tacataaata cttgaaaaaa ggcctgtttg aacataagaa tatccgaacg gtgatctgcg
    46141 tttctttcat atagaaagga attctccatc actgttcgga tattttttta tttttttcgg
    46201 ttactttctt ctaatacatc tgttagccaa tttgcatatt ctgtttcccg attgatcgca
    46261 tgcgctaaaa tcaggtagtg tccgtaattt tcatgttttt ctttttcagt aggaaagatc
    46321 gttttttttc gctctaatag atgaagtcgt ttttcttcat gaaggtcacg ctgctgctga
    46381 ataatttcta ctaatgccgg atcattcacg tctttgacga aatacaattt cagaacaaat
    46441 tcgtctcgat taaccggtag ttcattggtg ggtgtatgaa tccactctgc caattgttcc
    46501 ttcccttctt ctgttaattc ataaactttc ttttccaatt tttcacctgt gatctctact
    46561 tgatgctgaa tgattccttg ctcttccatt tttgcaagtt caggataaat ctgactatgt
    46621 tttgcttgcc aaaattctcc tatttcattt ttgaacgatt gattcaattc atatcctgtc
    46681 atcttcttct tacttaataa ccctaacaaa atatatcgaa gtgtattttt tcttgccatc
    46741 agttttccct ccttgacaaa tctttaaatc cattctatca taaatgagta atcgaaaaca
    46801 tgtagtttat tacatgtttt aatttataag gagatgctta aacatgaaag aatttaaaga
    46861 attggaagat tttattggaa ctcactttat ctatacgtat gataatggtt gggaatatga
    46921 atggtatgcc aaaaatgacc atactgttga ttaccgtatc catggcggaa tggtcaaagg
    46981 ccgttgggta aaagaccaag aagctgatat cgttaaattg acggacggcg tattcaaaat
    47041 cacttggaca gagccaacag ggacagacgt ggcattggac tttatgccaa atgaaaagaa
    47101 acttcacgga atgatctttt tccctaaatg ggttgaagaa catccagaaa tcactgttac
    47161 tttccaaaac gaacatatcg cagaaatgga agcagctcgt gaaaaatatg aaacttatcc
    47221 aaaattactt gttcctgaat ttgctactat cacttatatg ggtgatgcag gtatagacaa
    47281 tgaagatgtt attagcgaag aaccatacga tggaatgcca gatgatatcc gtagcggaaa
    47341 atatttcgat gaaaattata aacgagtaaa ataaggttgt gaaagagagg ttgtgaaatc
    47401 agcgttctga cctgagtatt agagaaagaa acggaaaaat agttcctcat gttttgccgt
    47461 tttttgagct aataccgagg gtcagctgat tgaacaccgt ttaagaaaga ggttgtgaca
    47521 gaagtggtca gcttcaagaa ataagaagga atttacggaa attgcttctc aaatttttgt
    47581 aaaatttcgg cttatttccg aagaagctac ttttggaaca ccgtgaatca gaggttgtga
    47641 aaaagctgtt ctgcatcaag taataagaac agccaaataa aaatagctcc tcatattttt
    47701 tgtttggttg ggcttattac cgtagatgca agcttttgaa caccgtttat caaagattgt
    47761 aacaactgca tattcacaca gttaaattag tgacttcaaa atgaaataat gctcccagca
    47821 aaaaattagg ctgggagcat tatttcgtta ttctgttcat caaaaatcag cgttttgatt
    47881 ccatttcatc acaagttcct cctcatttac tgcttcatct ttttgctgtg tttgaattgt
    47941 aaaaccttgt gaaagataga aatgaatagc tgattgattt ttttgataga ctgtcaaagt
    48001 cagtgtttta ttggtttctt ttattttttt cattagttgc gtaccgattc tttgttgccg
    48061 gtattccctt ttcacaaaga ttcctgcgat aaactgatca atcaccccag caaaaccaat
    48121 aatttcttga tctatttctg ctaagtaaat cactgcatct ggtaaagctt tcctaacaga
    48181 ttctacttga ttctcccaat aagttgatgg aatgaattca tgagaatcca agttagcatg
    48241 tagccaaatc gatagaacag attccagttc tttggcagac aattttgttg ttgtgcggat
    48301 cattttttct ctccttactt attcattgat tttaaaataa aaaccatttt tttgaagctc
    48361 ttttacaagt tttcgcccct caaaaaagta tatcttctct tgttttactt ttctaatacc
    48421 aaaagaaaca gcaactttag gatcatcagc tgaaacgatt cgataagtcc caccaggcaa
    48481 ttgatccagc ttgactttcc catgatggtc gctttgtact gaaaacggca caccatttct
    48541 agtaagtgtt tttttcttat gtttcaaaat gaatgaacta ccatttaccg gtttccctga
    48601 cgaatcacta ataataaatg aaaaatcaag cactttttta cttaatctat actgatagat
    48661 tagtcgtccg ataaacacta acagtatgac tacagctatt atcgttcctg caagaataaa
    48721 ccattgccgc atggttcttt cctgatttcc ttttccttct tcttttttta ccgattcgtt
    48781 ataaggaatc cgatgtcctg tcactagcaa acgatgcgtg ttgatcatat acggcgtaca
    48841 tgtaagcaag gtaactaagt cttctccttc tgcaatcgtt agaacagacg tgtcatctgg
    48901 cagtaccact tgtatatttt taacttgata agccaatttc tctcccaaaa cagtcaaaat
    48961 aaacgtgtct ccgttttcta aacgatctaa ttcggtaaat aaccgtcgat taggtaaacc
    49021 gctgtgagca gagatcactg aatgcgtcga atttccacca agcgggaaag aggttccttg
    49081 caagacgcct gctccatttt caaggatcct accattgagc cgatcataaa gtgaaatatt
    49141 taattggatc ttaggtatat tgatacttcc gatcagccat tcctctaatt ggctggatgt
    49201 tgtactttca tttctgttct tttcattgaa aggatcagta ccaggattga atccttggtc
    49261 agttaatcgt tggtttttct cctccatttt ctttcgctgc acttcaattt cagctgcggt
    49321 ccgtttttgt acttgttcga tacgtttttg atcaataaaa ctatttaaag aatccacata
    49381 aaatggatat aaagcgatca gtaaccctac gacgatacat attaataaaa acaaacgaaa
    49441 caaaagtcga cgagactgtt tttgcttact ctgcttcaca tgtgtcctcc cttgcaagtt
    49501 tttttgttct ttcttttatt atatgggttc aggaaaaaaa tagaaaatga aagccgatga
    49561 gattgtgaaa aagctgtcct gcatcaagta ataagtacag cctcaaaaaa tagctactca
    49621 tattttttgt tgggttgggc ttattaccgc agatgcaagc ttttgaacac cgtttaagga
    49681 agaggttgtg aaaactgcgt tatgctttga gtaataagag tgctagtcag aaaatagctt
    49741 ctcatatttt ctaggctagt gagcttatta ccgagaagca gctgattgaa caccatttaa
    49801 ggaagaggtt gtgaaaactg tgttatgttt tgagtaataa gagcgctagt cagaaaatag
    49861 ctttttatat tttctaggct agtgagctta ttaccgagaa gcagctgatt gaacaccgtt
    49921 taaggaagag gttgtgaaaa ctgtgttatg ttttgagtaa taagagcgct agtcagaaaa
    49981 tagcttttta tattttctag gctagtgagc ttattaccga gaagcagctg attgaacacc
    50041 gtttaaggaa gaggttgtga aaactgcgtt atgttttgag taataagagc gctagtcaga
    50101 aaatagcttt tcatattttc taggctagtg agcttattac cgagaagcag ctgattgaac
    50161 accgtttacc gagaggtcat gaaaaagcta ctttgtttcg agtattaaga aaaattctgt
    50221 ttcaaaacaa ggagatgcaa caaaacttat gtcgcatcct ctctccttag aactttcact
    50281 tatgtttttc ttgtaaaatt cataaatatt ttcatgaatt ttctaatttc ttgcctacct
    50341 ctcgcatagg atatatgatg aatttatcta aagtttgcaa aggagttcga caattgaaaa
    50401 aatatggccc atttttagca atttttttca ttgctttggc atttctcatg cctcatttat
    50461 tcacacataa actaattttg ggtgctgatg ccccattcca ttacaatcgg ttctatgatg
    50521 ccgcgcaaca aattaaatat ggggatttcc attattttcc ttccctttat ggattccagc
    50581 aaagtggcag gatcgtgaat accgtttacg gcccattttt cgcttattta caaggattga
    50641 tcgtgttgct tgcaggtagc tggtttcatt atcagattct ttcaaatttc attctttatc
    50701 ttatttcagg attttctatg ctgattttac tgagatatgt caatattcga aattgggtaa
    50761 gtgtaccagt agccgtttta ttcatgagta cgtattctat tcaatactgg tctatcaacc
    50821 aaggattcac tagctggggg acttgttttt atcctttatg tatgatccct attgctgatt
    50881 tcgtccttca taaaaagttt cctgttatca aagtcgctgt ctcagtggga cttatgacac
    50941 agatccattt actgtcttcg atcatgttag ctttgatgta tattcctttt tatctttatt
    51001 acttttttaa ccagactgaa aaaggaaaag cactgcttca actgattaag tcggtcttgc
    51061 tttattttgt tctgacagca aatatttggg caggattagc tattgtttac agtgggaata
    51121 agattcttcc tccctttgtt aacagagaaa tgagtcaaaa ggcgatagat ctggatggca
    51181 gttattggct ccattaccct aaggcctttc ctatattgat attatcaggt tttttgcttt
    51241 ttattttctt tcaacaaaag aacaccttat tccaaaaaat cgtgttgtac acaagtcttg
    51301 ttttcttttt tctttctact agcttgattc catggacgac attgatcgaa aaaaatgtgc
    51361 cttttattag tttgatccag tttccatttc gatttttcgt gccatttacg ctattgcttc
    51421 tactttacct tgccctttca ctgaaccagt ggtctgaaca aaagtggttc cgtcttttaa
    51481 gtatatttgg cattcttatt ttttcagcac agacgatcca gaacttatac cagcatctgg
    51541 aaaagtggga aaatgaaaca tttgtcagtc gacatactta tctattcgat acgccggaag
    51601 aagcaaggaa aacattcttc aacaaagata tgtctaccag cttgttcgtt ttccaaaaaa
    51661 ccacacctga ctatctgcca atctataagg agacaaaaga caataaatac gaccggtata
    51721 acgaagaaat actagaaaac gaaacaactt ttataaaaac acatccaggc ggtcttctga
    51781 caatcaagtg gaaaaacact ggggacaaaa ctgttcatat ccctgttatc gtctacgatc
    51841 ggactgtgct acagcaaaat ggaaaaacat tgactgatta tgaagtaaca gatatcggga
    51901 ccccaatcgt gaagcagcaa aaaggaatca acgagctcac gcttcattat caaacgccaa
    51961 tctatttcta tttcattctt tctcttactt tgattggctg gtttaccttg ctatgtttat
    52021 ttatttatca tagatacaag catttacgtg cttaggcaaa agggataaat gcatccgatc
    52081 aaaaaactct ccaaacggta taatcgtttg gagagtttta ttttaatcag tttttttatg
    52141 ttatatgtta tattttttat tcgttcacat ctaattcgat ttccaccccg tagtgatcac
    52201 tgatgattgg actatcgatc ccatcaaaaa tccgttgata ttttttaacc tgcattcctt
    52261 cagggacgaa aataaaatct atacgcaatt tttctgtatt ttgttcccaa ccatcgattt
    52321 tcttttccac agtagctgct tttccttctt cattcgcgac aacatacgaa tcttgaagaa
    52381 gaaggcaact ttctcttaca gtataataac cttgagagtc tactggatta ttgaaatcac
    52441 ctaggaaaaa aagtggtacg cgagtttcca aaaagtagtt ttccaagttt ttccactcaa
    52501 aataaaagcc acttttttta tctgtccacc aagaaaagtg gcagctcgag acaaaaatgt
    52561 cctgatcatc tatctttgtt ttcccaatca agatcttgcg tgtctgataa tcttctttct
    52621 tttgagattg ggagacggta aggacctgac tttccaatgt ttttttcgca agcagtgcat
    52681 ttccttcttc atatttatca taaccgatgt ggctcatttc ccaactccaa aaatactctt
    52741 ttccgtgttc ctttaaaagc tgaactaaac ggtaggcaaa attatcttta cggataggta
    52801 cttgattctt taccggacag aacttcatta gcttcgcagg ttctacttct tcagattcca
    52861 gtaattggtt gatttcttgt aaagcaatca cttcataatc ttctaacagg atcttatctg
    52921 ctaattcttg caattttttc tctggttctg gctcaagcca gctatgcgtg ttgagtgtca
    52981 tgaatttcat tggttttctc cttgtcttca tttcgaaaca aaagggttgt gacaaaattt
    53041 ttgtcacaac ctctccagca aatagtgttc tcctgctaac tcctcagtaa taagctcaat
    53101 ggaccaggag ctattttttg tttggctgtt tttatcactt ggtgcagggc agctttttca
    53161 cgacctctcc actaaacagt attcaaactg ctgcttctcg gtaataagct cactagccta
    53221 gaaaatatga aaagctattt tctgactagc gctcttatta ctcaatgcat aacgcagttt
    53281 tcacaacctc ttccttaaac ggtgttcaaa agcttgcatc tgcggtaata agcccaacca
    53341 aacgaaaaat aggaggagct atttttgttt ggctgttctt attacttgat gcaggacagc
    53401 tttttcacaa cctctcgata aatggtgttc aatcagctga ccttaggtat tagttcaaaa
    53461 aacggcaaaa tacgaggagc tgttttttcg ttttgtttct ctaatactca ggtcaggaca
    53521 atgatttcac aacctctcct tacattttaa tggagccgat cactttacca gctgtcactg
    53581 tatctaattg cttgatcact acttcttcta ctttatcgtt tgtaaatacg atcatgatcg
    53641 ttggatcttt ttcttcattt tggatcacct caagatccat ctcagctaat ttcgttcctg
    53701 ttcctacttc ttggccttct ttgacagcaa tctcaaaagc tggctgattc atttggactg
    53761 tatcgatacc catatggatc aaaacttcga taccatcttt cgtctccagc ccaattgcat
    53821 gtttgcttgg gaaaatactt gtcacttttc cagcgatcgg cgcaacaact tctcttgatg
    53881 ttggaataac agcaaagccg tcacccatca ttttttgtga gaataccgga tcttttactt
    53941 cagataaagg aatcacttct ccagaagctg cggaaactag ttcttgttct atacctaagt
    54001 attgcttact atctgcttgt ctatttcctg tagaaaccat ttctggctct ggaatctctg
    54061 ctcctgattg cagcagatct tcgatatctg atttcaagac atctgctttt ggtccataaa
    54121 ctgcttggac tccattgtct ttgacgatca atcccatcgc ccctgctcgt ttccaggctt
    54181 cttcagtccc tactttttct cgatcattta cacttacgcg taaccgagtc atacaagcat
    54241 cgacatcttt gatattttct tttcctccca gcaaatgaat gatctggacc acttgctgat
    54301 ctgctgttcc tgttccgctg ttagatacaa cggtttcttc actgtcattg tcgtaatttc
    54361 cgttacgtcc cggtgtagca aagttgaatt ttttgatcaa gaaatttgct aagaaatacg
    54421 taacaacacc aaaagcgatc acacacaaca cgaagttgat aagatctcca cctaaacccg
    54481 ctttgatagc taacggtgtc cgagtcagca attcgatatt cccaaatgaa tggacccgca
    54541 atggcaagat atctgccatc gcaaatgcag ccccttggat cactgaataa atgacatata
    54601 atggcacagc agcaaacata aacatgaact ccaatggttc tgttacacct gttagaaaga
    54661 cagccaacgc tgctgaaaaa tacattgatt tatatcttgc tttcttatca ggatcgacat
    54721 tacgatacat cgcaaaagcc attcccatca agatacctga agaaccaatc atttgtccta
    54781 ctttgaaacg agccggcgtc cagttatgca acacaaactc atattgcgac atatcccctg
    54841 cacctttaag attcactaaa tcagtggccc aagccaacca taacggatct tgcccaaata
    54901 cttgtgtccc cgcctgtgcg cctgataaaa tctcatacga tccgccaagc tgtgtatagt
    54961 tgataggaat cgtcagcata tgatgcaatc caaatggcaa tagtaaacgt tctaatgttc
    55021 caaataaaaa cggtgctaga atcggtgcgc tttcttgtga ttctgcgatc cataaaccaa
    55081 aattattgat tccagcctgt acgtttggcc acaccacagc aagaatcaat gccacgattg
    55141 ttgaccataa gataacaaca aacggaacaa agcgctttcc attgaaaaat gacaaagcat
    55201 ccggcaattt tctataatta tagtacttat tataagccat tgccccgaca aatccagcga
    55261 tgatccctac gaatactccc atattcaaag ctggtgcttc caatacactt gtaaaaaatc
    55321 ctttaaccat gatcttcgta ccgaacagag tgtgggtaaa tgcatcttca ttcgcaagca
    55381 tgtcacttgt gacaccaaag atagccccag tgatccgatt gatcaaaata aatgagatcc
    55441 cagctgcaaa tgctccgcct gctctttctt ttgcccaact tcctcctatt gctaaagcaa
    55501 ataaaatatg aagattacca ataattgccc aaccaatatt ttcaattact ccgctcgttg
    55561 tgacaagcgg cgtccaatca ggattgatca agggaattga tttccctata ctgatcatca
    55621 acccagctgc cggcataact gctaccacaa ccattaaagc ctttccaaat ttttgccaaa
    55681 actcaaaact aaatatcttt ttcattccgt ttagctcctt tacgcaatcg gtttcgttaa
    55741 acgtattata gcgtgcgttt tcttttttgt aaatgcttta ttttttattt ttctgtctat
    55801 accattctag aaaacctata atgcgtgtgt tcccttctat aattttctcc taaaaattta
    55861 tttttttatg cttttttcta tgaaatattt tcttttgtct attgacttgt gcaatcggtt
    55921 gcgtttatta tgaacgtata aaacagctca ttaggaggag aaaaatgaaa cagatcaaac
    55981 gactatttgc tattgatcca tggaaaatca gcacgacaca attagataaa aaaaatcttc
    56041 gactgcaaga atctttaaca agtattggaa acggttatat ggggatgcgc gggaactttg
    56101 aagaaactta ctcaggggac caccatcaag gtacttattt ggcgggtgtc tggtatcccg
    56161 ataagacacg tgtcggctgg tggaaaaatg gttatccaga atactttgga aaagtgatca
    56221 acgccttgaa ctttatcgcg atagatattt cgatcaacga tcagctgatc gacttggctt
    56281 ctttggaacc agaagacttt tactgggaat tagatatgaa aaatggtgta ttatctcgta
    56341 cattcacaat cactacttct actaataaag tacgcatttc cttcgaacgt tttctgagca
    56401 ttgtcaaaaa agaatcagct tatatctatt taactataga aatgcttgaa ggtagcggaa
    56461 cagtcaaact cgtatcaaaa ttggatggaa atgttcaaaa cgaagacagc aactatgatg
    56521 aacatttttg gaatgagatt gatcgtggaa ctatagaaga aatcggctat ttgacgacta
    56581 aaactattcc aaacaacttt gggattgaac aatttactgt tactgcagca atgcgccatt
    56641 tcgttaatgg aaaatcagtc atccctgact atcacgaaga tactttagca ttacatggtt
    56701 gcttgtctgc agaattatct caaggtgaga catggtcagt ggaaaaagaa attatcgttc
    56761 ttactagtag agatattcca gaagcgcagc aagcagaaaa agctgtctca gaattaacga
    56821 accagacaaa caattatatc caagcaaaag aagagcaaac agcggcttgg gcagaacgat
    56881 ggaagcttgc cgatgtggtc atcgaaggag acgaagaagc acaacaaggt attcgattca
    56941 atttgttcca actattctct acttactacg gcgaagatga acgattgaat atcggcccca
    57001 aaggattcac aggagaaaaa tacggcggag ccacttactg ggatacagaa gcgtatgctg
    57061 tccctcttta tcttgcttta gccaaacctg aagtaactaa gaatctgctg aaatatcggc
    57121 ataatcaact gccgcaagca atccacaacg ctcagcaaca aggattaaaa ggcgcgcttt
    57181 atcctatggt caccttcact ggtgtcgaat gccataacga gtgggaaatc acattcgagg
    57241 agattcaccg aaatggcgcg attgcctatg caatctacaa ttatacgaat tacaccggcg
    57301 atacggaata tttgaaaaat gaaggactgg aagttttagc agaaatagca cgcttctggg
    57361 cagaccgtgt ccatttttca aaacgagcaa ataaatacat gatccacggt gtgaccggcc
    57421 caaacgaata tgagaacaat atcaataaca attggtatac aaatacgatc gcagcttggg
    57481 tcttgcgtta cacgcgagaa aattatttaa cttatcaaaa agaagctact atcactatca
    57541 gcgaagaaga actagccaaa tggaaagata tcgcagagaa catgtacttc ccagttgacg
    57601 aagaattagg aatctttgtc cagcatgaca cattcttaga taaagatctc atgcctgtat
    57661 ccgatattcc cacaagcgat cttcctctaa atcagcattg gtcttgggac aaaatcctta
    57721 gatcttgctt catcaagcag gcagacgtac tacaggggat ttatttcttc aatgatactt
    57781 ttacaaaaga agaaaaacaa aaaaactttg atttctatga accaatgact gtccatgagt
    57841 cttccctttc gccaagtatc cattcgattt tagcagcaga attaggaatg gaaagcaaag
    57901 ctgtagaaat gtaccagcga acagctcgct tggatttgga taattacaat aacgacacag
    57961 aagacggctt gcacatcact tccatgactg gtagctggtt gtcgattgtc caaggatttg
    58021 ctcaaatgaa aactgcccat gatcagttga gattcgcacc atttctgcca aaaacttgga
    58081 aagcttattc tttccatatc aattatcgcg gacgtttatt gttcatctca gtcacagatg
    58141 aacaagttac tttcgagtta ttagaaggtt ctcctctaga aatttacgtc tatgaacagt
    58201 cttattcttt agcggatcgt ctagaaataa cgctaagaaa ggaggaagca aatgtttaaa
    58261 ggggtattgt ttgatttaga cggtgtcatt accgatactg ctgaattcca ttatcgtgct
    58321 tggcgaaagc ttggtcagga aatcggcatt acgatcgatc gtacattcaa cgaacagcta
    58381 aaaggcgtca gccgagaaga ctcactctct ttgcttttag ctcatggcgg aaaagaacac
    58441 tctttttcaa aggaagaatt tgcagaatta gcgaaaagaa aaaacgatta ttatttagag
    58501 atgatccaga cgatcgaacc aaaagatgtc ttccccggag tcgtgccttt actagattct
    58561 ttaaaagaag aaaaaatcaa gattgctctt gcttctgcaa gtaaaaacgg gcctttccta
    58621 cttgaaaaaa tgggtcttac accttacttt gatgctattg ccgacccggc agaagcaaca
    58681 aacggaaaac ctgcgccaga tatcttcctc cttgcagcaa aagctgtcgg actaaaagca
    58741 gaagaatgta tcgggatcga agacgcgcaa gccggtatcc aagccatcct ctcaagtggc
    58801 gctcaaccaa ttggcgtggg acgtgctgaa gaccttggag aggagatccc gcttgtccct
    58861 gatacgactt ttcttacgat cgattacttg aaagaaaagt ggcatgacca tggataatcc
    58921 agaaatctcc gtcgtaccag ttccagagac tgaaataaag aaaatcacat tgaagaacga
    58981 ctacttagaa gtcgttcttc tcaattacgg tgcccgcctg caccaaatct tcgcaccaga
    59041 caaagaagga aaatcagaaa atgttttatt gtcttacgat cgtttcgaag atgttctaac
    59101 agacaaaagc ttttttggag caactgtcgg acctgtagcc ggaaggatcc gggatgcttc
    59161 ttggggtgag catagattgg agaaaaactg cggatcacac catatccacg gtggcacgaa
    59221 aggctggtct ttccaatttt gggaagtaga agttttcaaa actccatcat caataggtgt
    59281 ggtcttttac ttaaaagatg aattttctac ctatccagga ccaatcactg ctacgatcac
    59341 ttaccgttta acaaaaaacg aattagagat gacaacctct gctagtagcc ttgttgaaac
    59401 catctgcaat ccgaccaacc atgcctactt caacctttca ggaaatggaa caagagacat
    59461 ctatgaacat cagttaacgg tctttttaga tggtgtgctt gaattagatc aagaaaaact
    59521 gcctactgga aattggacaa aaaaagaaga actgccaatc gactttagaa aatccccaac
    59581 actgcaagag atccttgcat gttatccaga tggactagat gatgtatttc ttttgcatca
    59641 tcctaggctt tccaaaactt ccttacaatt attcgagaag cattctggtc gcaaaatgac
    59701 tatagcaact tctaataaaa gtatggtatt attttctacg actggattcg aagctgattt
    59761 ctctgtcaat ggaaaacaga tgcattcaaa ctacggatta gcaatcgaac cgcaagaaat
    59821 ccctgatatc gttcatttcc ccaaatttgg atcgatcaac ctccatcctg gtcaagaacg
    59881 gatcagtcag acgatttatc ggttctctgc acaataacaa gagaaaggtg tttttatcat
    59941 ggctattacc gtaaaagatg tggcgaaaaa agccggtgtt gccacctcga ccgtctctcg
    60001 tgtcatcaac gatcatccta gtatttccga gacaacaaag aagaaagtcc gaaaaattat
    60061 ggatgaacta ggttatgttc ctaacatgac tgcccgcaat ctaggaaaac gcatttccag
    60121 tgccatcggc gtaatcttac cccctcttga ttcaaaagag cggatcggta acccatttta
    60181 tcttgagatc atggaagcaa tcaacgaaga agcgcggaat tatgatatga ctacagcaat
    60241 cgctactgct aaaaattttg aattgctgtt agagaacgtc cagcgtatgc atttacaaaa
    60301 acaagtagat ggttttattc tagtgtattc agatagtcaa gatcctgtca ttgattattt
    60361 ataccaaaac cacatccctt tcactttgat cggacagcct tatcatcatg agaacgaaat
    60421 cgtttatgta gataatgata accagcttct aggtaaacaa gcaacagaat ttttgatcca
    60481 gaatggacat aagaatatcc tgtttgtgac aaacacgact catgaaagtt tgtatttcga
    60541 acgatatttc ggttatcaaa aagcaatgat gatggctggt cttcctgcgt tatccagtgt
    60601 agtactagag catccggaag attatctgtc ctttgagaaa acgttgaaag aaaacgaagc
    60661 cacagcattg gtggtcattg acgatatctt cgcccttcgc acgatgcagt tggcgcaaat
    60721 gtacggctat gtcattccag agacactctc cgtcattagc ttcaacaact cgatcttctc
    60781 aacattaaca cacccttacc ttacaagtat cgatatcgat atctccgaat taggacgtgt
    60841 cgctatgcaa aagctgcgcg aattgatcca tgaagaattg agcagtggcg tacgtttggt
    60901 catccctcat cgcttgatca aaagagagac agtcgttcct ttagaaaacc catactaaat
    60961 agctgactca ctaaatacgc tgaccattta tcctatggtc agctttttat gtaaaagaag
    61021 atactacttc taacacattg tttatctgta aaaaagagcg tgggacaaaa gtaaagaaca
    61081 cttttgtctc acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa
    61141 taagctgaaa ttcacaaaaa tttaaaaagc aattttcttg agtttcttct tatttcttgg
    61201 agttaaacgc ttctgtccca gcctcttttt tccttccttc aattttttac acgtcgacga
    61261 ttcaataaaa aaccgcctaa tattgtaaag acaggtgcaa gaatcgagaa aaaggcgaat
    61321 ggcaagtaat gcaacgcgct aactttcatc gttcccataa tgaatgtgcc gctgactccc
    61381 cacggtacga gagaattgac ggtcgcacct gaatccgcta gtgttcgtgt caaataggtt
    61441 tttgataagc caacgtcatc aaaagaacgc ttgaatgttt ctcctggaag aatgatggac
    61501 agatactgtt ctccaacgat cagattgatt ccgatacagc tcaaggcagt aaacccgact
    61561 aaacgagaag gtcggtccat cttttctttt aattcttgaa cgatggtatc aacgatcaga
    61621 tatttgatca gtaacccacc taatgccaat gcaagtaaaa tcaaactagc agaacctaac
    61681 atactcatga tcccgcctcg agaaagcagt tcatctagct ttggatcagg tgtatttgcg
    61741 acataaccat tcatcaagat gtctgctgct tttccgaccg tcaaactttt ctcatggata
    61801 aaagaaagaa cgagagcagc tgtcgatccc gctagtaatg tagggatagc cggaatcttt
    61861 ttgattgccc ccccaaataa aataactagt ggaatcaatg tccaaggaga gatccaaaag
    61921 ctcgctttca tgttttggat catttcattg atactagcta gatcggctga atgactgtta
    61981 tgtcctaata tcgtataaaa aatcaacgaa aggacgaatg ctgggaaatc cgtataacgc
    62041 ataccagcga tatgttcgaa tagattaact cctccaatac ccgctgccaa gttggtcgta
    62101 tctgataaag gcgagcagtt attccctaaa aaggcaccgg aaacgactgc gcctgtagtc
    62161 attgcatcat tgaatccaag taaatgaccg atccccaaaa aagcaattcc aatcgtcgaa
    62221 atcgttgtaa atgaactgcc gacagtcact ccgacaattg cacaaacaag aaatgctgtc
    62281 ggtaaaaaga aacgcacaga aacaagttta aatccataaa ccataatcgt agggatggtt
    62341 ccagataaaa tccatgaagc aactaagaca ccaatcaaaa gaaaaatcag gattggaatg
    62401 atccctggag tgattccttt gatgattccg tcatggatct catcccatgt gaacttttta
    62461 aatctgccat aaaacaacaa acacatgaaa gctgcaagga tcgggatatg tggcgagagc
    62521 tggaatccga tgatcagtac tcctaggagt gccaacaaca cgatcaatac agcgatactt
    62581 tcttttaaag aaatattttt attcatcgtc gatctcctat ttcaaatgaa aaggccctgc
    62641 catgaaaaaa ctattcactt ggcaggacct cctactaaat cagcgacaaa acgtcggctg
    62701 aaagacttat ttttttattt ttcttctaaa cttttttcta cctcaatccc ccaagaatct
    62761 ttcttgaagt gattgatgat caatggaata acgaacatga ccactgtgat agctgctact
    62821 aataatgcat cactcaatgt cgctgtacct aatgtagcaa atacgacaac gatgatagag
    62881 aagatcagca tgcagctgac tacccaagct aatccgtttc cgtttttacc aattcggtaa
    62941 ggacgttcga attctggatg tttcttacgc attttaagca atgaaacagc aatcaaaatg
    63001 tacacgatac aataaataac agttgtagca tttgtaagtg tcaagaatac agcacttacg
    63061 tcatccatta caccataaag caaagcaaat aatgaaataa cgattgattg tgttagaacg
    63121 acatttctag atacgccgta tttgttttct ttatggaatc cgaattttgg tggaaggaat
    63181 ccttcacgag ctacttggat gattgttttt gatggtccag taacccaagc tgataattgt
    63241 aaaagcacac caataaatac catgaagctg aagatatttc cgatcacttc tggtaagcct
    63301 aggatttgac agtcaatcaa gataggctgc gtgatatttg ctaattccat ttttccatct
    63361 ggtacgacat ttgctacaag catcgcattg atgacattca ataaaactaa tccgatcaaa
    63421 gcgataaata cgccttttgt ataatttttt gttgcgtctt tcaaacgagg catgtaaaca
    63481 gaactcattt cgatcccaac aaaaataaat gtgataccag ctaagtattt caatgaatca
    63541 atatgttcca agtcagggaa agcttttgac catgaaaagt cacctagata gccgtttgag
    63601 actagtccga ctttgaaggc tgccaaaaca cctaaaacga acatgatgac tactgggata
    63661 tataccccta gccatacacc gatgttcccg ccgacttttg ccatatcgaa tttcaagttc
    63721 aagatcgtga tgatccagta gataactaaa atacaaccta aaacgaacca gtgattattg
    63781 ccaagttcta cattaccaaa tgtgtttcct aacaatggtc ctaaagtaga agcgaccatt
    63841 accatacctg ggaacatttg cacccataat agccatgcaa cgacaaatcc ccatttgctg
    63901 cccagtgctg tttttaccca taactgagga ccgccttctt gaggaagcat cgttgaaagc
    63961 tcaccggaaa ccattgatat cggaccggca aaaaacaaaa ctgcaaaaat tgaataaaaa
    64021 atcaatgtcc aaccgactgc ggctaacgta ggaatactcc gaaccgttgc acacagtgcc
    64081 attgtcagac cgataaaggt cccaagaccc attttactta cttcagattt actcaccgtt
    64141 gacactctcc ttgatttttt ggataaaata acgatgtctt tgaagtagtt tcagcaataa
    64201 acgaaacaat tcagcgaata tttgagggga ttctttgagt ctattgcttg aagggtttct
    64261 tcaaagacaa cctcaaaaca aagggatcga agagcttagg tctccccttg ctcttcagat
    64321 ccaaacatgc gtcagaaaca gttagtattc aagctgtttt ctaacatgat taccttgctt
    64381 attttgcttc gcttgccaat aattggtctg cgtagatttt ttccaatttt tcttgaagag
    64441 ctgctttgat tttttcagca tattcttcaa agtgttcttc tttgttcatg tatggtgtca
    64501 ttacgctggc acgcaataca gttacttttc cggcacggtt ccattcttca tctgtgaatc
    64561 ctagttggtt cacaaattgt aatgggctgt tgccatagtc tgggatagca aagtcagtat
    64621 gtgaagttaa gaactcatta ccgtaaatgc ttcctttcac gtatgaagaa taatcatata
    64681 cgtcatggtt caatttattc attgcaacta agtcatcgtt gcctttttct ttgaatacgt
    64741 agtctaccat attgaaatct ggataagtta atggatgaac ttcgatttct ttgtctccta
    64801 ctttaaatga caagtcattc aagaagttgt agaaacgatg tgcaccttcg attgatgcac
    64861 ccattaattt accatatcct gtgacattca aaggtaagac atggtgtgct gcccaaacgc
    64921 tggctgctgt tgcccctgct tttgaacctt ccaagatata agccccaagt aatgctggga
    64981 tatctgcgcc tttttcaaat acatatgtcg caaagtaaga gataacgtct ctcatgcgga
    65041 tatctttgat gacgatacca ccggcagaat atggaacata gcccatttta tgtgggtcaa
    65101 tcgttacaga ttctgcttct tcgattgctt tatatgcact gtgtacttct tctaagatat
    65161 aatctttgtt ttctgtaaag acattgtatt tgtaatgaac atcttttaaa tcttcaaatg
    65221 gaatgaagtt gttgtcttcg tctaagaaaa tcgcacggcc gtatccgcca taagcagcat
    65281 ctacgtgtaa gtagaagtaa ataccgtctt tttctaatac gcgacgcaat gcaacgattt
    65341 tatcgatacc gtcgattgct ccttcttctg ttgatcctac aacaccgact acacctagga
    65401 ttggtgtttt ttcagctgct agaccacgaa cgattttttc aagttcgttg atgtccatgc
    65461 gatagttgtg gtcaactggc actggaatca cttggtctaa accgataccg atgatgtcgg
    65521 cagcttttag ccatgaatag tgtttagttt gtggaaccaa ccattttcct aatttttcta
    65581 aatgttttcc gctacgtgct gagtgagctt tgatttcgtc gattttttct gggacgctgt
    65641 ctaacagatt catgatttct tctgttgaca agttcattaa ttcccaatcg ctttttccag
    65701 caactagttc aggtgtcact tctttcattg caagcggcaa tgatttgatg ttgcgggcat
    65761 accaaagtcc ttctaagttt gctaaagaac catcagcaac gatgtggccc cagccatctt
    65821 tatagctcat taattttgca aattccattc ctacttcttc ttccatttgg cttgttgcag
    65881 gagaagattc ataggcaacg ttattaccat tccatagcat agcaaaattg tacgctagta
    65941 aagatggcat caatgtttca gagttcatat gaccccagta acgtccggca ttatgccaag
    66001 gaacggaatg ggtacgcatc cgcgctgaaa tttctgatag aacatccttt gttttattca
    66061 cagtgtgttc aaaactagca ctgctttttt cttctggcgt aataataggc atgtcttgag
    66121 gcatgtagtt ttgacgccag cctaaatgtt catccaccaa ttcattcaac aaagctttat
    66181 agatttggcc gttctcagct ttgtccccaa tgaatagggc atttaggttt agatctttcg
    66241 acaatgattc actcatagtg aaaccctcct aaaaaaatat ttaaattttg tcgagcccta
    66301 cattacacct gttcttctat tctgtaaact aagttttggc ctgattttta atcatatttt
    66361 aatatgtatc aattatccga attgttcaca cttttgaaat aattaaaaaa aacgagggaa
    66421 tttacaaatg taaactccct cgcaaagatt gtattaacga caaccagcgt tctattttag
    66481 gatgggtttc aaaattggaa tgttgtaata gtatttccct ttttcaaggt aaaaacttac
    66541 taaattctaa tcaattactt tggccaaaaa gtaatttttc ttaccttttc gaataaccac
    66601 aaacttacca tcgaattcat cggatggatt tatgacaaaa tttaaatcgg taacgcggtc
    66661 accgttaata cttatagctc cgtttgaaac atcttcacgt gcttgacgtt tagatggttc
    66721 aatttttgtg gaaacaagca gttccacgat attttcaggt gtgcttgaaa tttcaacgtt
    66781 cggcatttta ccgaatcctt gcgcgatttc ttccgcattt agttctttaa tatttccaga
    66841 gaacaatgct tgcgttattt tttgcgcttc tttcaagtct tcttcactat gcacaaatct
    66901 tgtaacttct tctgccaaac ggcgttgtgc ttcacgtttc tcaggttctg tctctacttt
    66961 tttcgctaag tcttcgattt cttcttgaga caagaaagta aagaatttca agtatttcac
    67021 tacatcgcga tcatcttgat tcaaccagaa ttggtagaac tcaaatggtg aagttttctt
    67081 cggatcaagc caaacggcac cgcctgcagt ttttccgaat ttcgttccgt cagccttcag
    67141 catcaatggg atcgttaaac cgaacgcttc tacttctggt ccttctaatt ttcggattag
    67201 gtctaatcca gctgtgatat ttccccattg gtctgctcca ccgatttgca attgcacatc
    67261 gtatgtttta tgcagatgca aaaagtcgat agattgcaga atttggtaag taaactctgt
    67321 aaatgagatt cctacttcca aacggctggc aacgatatct tttgctaaca tcgtgttgat
    67381 gttgaagttt ttaccgtagt ctctcaaaaa ttcaagtaaa gagatttttg acaaccagtc
    67441 gtagttgttc acaaatgtga tatttgcatc tttaccaaac aattttctca tttgattgga
    67501 aagtgcgtcc acgttatgtt gcacttgttc catcgtttgc aacacacgtt ctgttttgcg
    67561 gccgcttggg tcgccgatcg ttcctgttcc gccgccaatc agaatatatg gatgatggcc
    67621 tgccaattgg aatcttttca tcatcataaa tggaatcaaa tgtccgatat gcatcgaatc
    67681 accagttgga tcaacgccgc aataaagtga aatgctcttt tcttcaacga gctcgcgaag
    67741 tctttcttcg tttgtttgct gattaatggc gtcgcgccaa gttaattcat caataatatt
    67801 cattttactg acctccgtgt agttttttta tgaaagcagg aacctgctag catgtgtaat
    67861 taattatttc ttcaggatag gataggaaat aaaaaaagtc ccttggcata taagccaagg
    67921 gacgaaatct cgcggtacca cccaatttgt atgtctagat atccaacata cctctcgaac
    67981 atttaacgct gtcgcgtggc aatcactgcc aaagactcct gaaatgtaat tcgctttaaa
    68041 gcatgtactg gtttgcagcg accaccagct ttctgaaaca ttggctttaa caactacttc
    68101 gtttcgatct tcgtcttgtt attattaata tgtgtctatc atagagcgca actttttctt
    68161 tgtcaacaga aaaaggatat tttttttaaa ttcctcattt tttctttttt gaatccgctc
    68221 taattccgaa cattttattt tcaattattg ttaaaagaaa taactttttc tgtatttttt
    68281 ctgcaattta tcgagaagtc actttacttt gcctcttatt ctttcttcgt tacaataagg
    68341 aatgggacaa gtaaaaaaat gaaaaagcaa gggacgaggt atatggaaaa aaagcaaaaa
    68401 attattttag gagccacttc tgctttaact atcgttattt taattctaag tttgtttttt
    68461 gtcatccgat catctacaaa aaaagaacca atcattcctg aaaaaaaaat aacagaaaaa
    68521 gcaaaagaac cgacagatga taagcaacaa ctagttactc aagcaaaaaa tctggctcaa
    68581 agctacgatt atgaccaagc gattgcgtta ttggaaaaag atagtaagaa cggatctact
    68641 gaaacacaac agcttcttca aacactaaaa aaggagaaag aacaactgat cgactggtct
    68701 gatcctactc agatctctca tgtctttttc cacagcttga tcgtggaccc gcaaaaagcc
    68761 ttccactctc aacaggcaca aggatacaaa gattatatgg tgactgttga agaattcaac
    68821 cgttcgatcg aacaacttta tcaaaatgat tttgttttag ttaatttaaa tgatttgatc
    68881 caaaaagacg aacaaggaaa tctttccttt aacgggcttg cgctacctga aggaaaaaaa
    68941 ccattggttc tttcacaaga tgatgtcagc tattatgaat atatggataa ttccggtttt
    69001 cctagccgat tggtcgtatc aaataacaat gaaatcaaaa atgtctataa agagaaagat
    69061 aaagaagaaa tcggtgactt tgacatggtt cctctgatcg atgcctttgt caagaaacat
    69121 cctgattttt cttatcgagg cgcaaaaggt accttggccc tgacaggtta caacggagtt
    69181 ttaggttatc gaacatcaaa atctcaatat ggagacaatg aaaaaacaaa aaaagagatt
    69241 aaagaagcta aaaaagtggc ggaacagttg aagaaagacg gctggagctt tgcttcccat
    69301 acatggggtc acttgaatat gactcaagct tcactagaag atgtaaaaaa agacaatgaa
    69361 ttgtggcagc aagaagttgc acctatccta ggaaaaacaa atattctgat ttatccattt
    69421 ggtgcagaca tcagcgactg gcagccttat tcagcagaaa atcaaaaatt tgcttacttg
    69481 aagagtcaag gtttcgatat tttctgtaat gtcgatgctt ctacaccagc ttggggacaa
    69541 ttaggtacgg atttctatcg aaatgctcgg atcaatatcg atggcattcg ttttcaatct
    69601 gatttagacg gaaaaaatcc tattcttgat ccattcatca atgtccatga tgtctatgac
    69661 aaagaagcac gcgaatctgc ttgattttac gtcatttatg aaccaaaaaa gccgaactga
    69721 cattttatcg tcagtttcgg cttttttatg ctttatttct tcttcggtgc gattcccttg
    69781 atcaggactt ctgtccattc tgctgtatat ggaagcagtt ttgcgtatat ctccggctta
    69841 gaaattcctt ctaccattgc ttgaaaatag aggatcaaga actcatccga atatttcaaa
    69901 tccacttttc cttctttccg ccctcgatgg aaaagatcaa gcatgatact gaaactttct
    69961 tgcgtatacg catccatcgc gtcagaaaat tctttttttt ctttttttgt atagtatgtc
    70021 atcaaatcga tataaaattg tttgttcact cgattgagat aacggatttt gttttcactc
    70081 atggcaatca gtgtttcttc aaatggaaga ttttccgcaa tcaacgcttt cgcttcttgc
    70141 cctaaatcat tcataaatgc aaaaaatact tcataaatca gcccttcctt gctgccaaaa
    70201 tatttaaaaa tcgtcgcttt acttacctga gcgttctcag ctaccttatc cattgtcact
    70261 ccagcggttc ctatgtctgt gttcatcaag tcaaaagctg cttgtaaaat ctctttcttt
    70321 ttctcttgtg ctctcttttc aaaaccgttc atttgtagag cctcccgtaa ttttaaactt
    70381 ttataatata tatagttcaa atttattctg aggtttatta taactatcta ttgagaaagt
    70441 atcaagctag caattccttg tttatgaatt cattgacaga aatttataaa aagaatatta
    70501 tgtactaaaa taataaaaaa agttttataa aaaggtataa aaccttttta ttaaactatt
    70561 taatcttgtt tagtatatat ttttagaaaa aggagtgggg tttttatggc agaaatcgtc
    70621 aaagtcacac atttgaaaaa gagctttggt cgtttcgaag ctttaaaaga tgtctctttc
    70681 accgtacatt caggtgaagt cgttggattt atcggaccaa atggttctgg aaaatccacg
    70741 acgattcgga cacttttagg gattataaaa aaagacggcg gaacggcaac gatttttggg
    70801 caagatgtat gggaagatag tttatctatc catgaacgtc tttcttatgt tccaggcgat
    70861 atctctttgt ggggaaattt gactggagga gcgatcatcg atctcttcat gaagcttcat
    70921 ggaaaaggga gtgctcaaaa aaaagatgaa ctgattcaac gtttctctct tgatcctaag
    70981 aaaaaagcaa aaaactattc aaaaggaaat cgccaaaaag tgggcttgat tgctgctttg
    71041 gctgttgatt cggatctcta tttatttgat gagcctactt ctggtttaga tcctttgatg
    71101 gaaacgattt tccaagaaga agttgaaaaa ttgaaagaac agggcaaatc catcctactt
    71161 tcttctcata ttctcagtga agtcgagcga ctagcggata aagtcgtgat catacgcgaa
    71221 ggaacagtcg tagaagaagg aacactcgat gaattgcgtc atttgactcg ttcgaccatc
    71281 actatagaaa cagaagcaga gaatagtcac ttagcacaat tgaacggtgt ccatgacttt
    71341 gtgcaaaaag gtcacctcgc tcaatttgct gctgataacg aagctttcga tgtgatttta
    71401 gctgaagcgt ccaaattagg tgtgaaaaaa tttgaatcta ttccaccgac tcttgaggat
    71461 ttattcatga gacattatga aggatgagga ggaagcgaaa tgactgataa attttcacgc
    71521 tggtccaccc ttttttctca aaaccttagc cgtgactgga aaaagatcct gatatggcta
    71581 gtcggtgtca ctgctttttc tggtggtttt gtccctgcgt ttgaagaatt gacttccgga
    71641 caaggattag ctggattata cgaaaccttg caaaacccgg caatgattgc aatggtcgga
    71701 ccaactccag cttcgaatgc tgctgagtat actttaggag cgatgtatgc aaatgaaatg
    71761 ttgctttttt gcagtttgtt tgctgctgtg atctctgttt tacacgtggt gagccaaacg
    71821 agaaaaaaag aagaacttgg tctgattgaa cttattcgtt cctttcgagt cggacgtcaa
    71881 gcaaactctt tagctgtcat cgctgaaagt attctgatca atttgctttt agcaatatcg
    71941 atcagctgta cgatgatttt tttccaagca gattcgatca ctgcagaagg tgcttggctt
    72001 tttgggctat ctgtaggtag tatggggatt ttggggagtg ccgttgcact gtttgctgca
    72061 caactgatgc caagttcagc cagttcgaat ggtctgtctt tagcgttttt aggtggactt
    72121 taccttctac gagcaataac agatgtagct gattcctccc tttcgatgtg gaatccttta
    72181 ggctggtctt atttgaccta tccatttaca actaacaact ggattccttt gctttatttg
    72241 tttttgttca gtctaatctt gataatcagt tcatttgttt tagaggaaca tcgagatttg
    72301 aacaccggct atatccccga acgtgaagga aaaccgtatg ctaaacgttc tcttttatcc
    72361 ttgcgtggtt tattattcta tctaaataaa gggatgacaa tcagttggct tatcactttt
    72421 ggtttgatgg gggcggcata cggctctatc tacgggaata tgcaacagtt tttagaaagt
    72481 aacgacttaa tgaaacagat gtttatccaa tctggcgtct caattgaaaa aaactttaca
    72541 agcacgatca tggtcgtctt gatttgtcta gctgctattt taccaattgc tagcatcaat
    72601 cgtttattta cagaagaaac ccacggacgt atgaatcagc tgttcgcaac aaaaatttct
    72661 aggaaccaac tttattggac caatatgtta ctagctattc tatttgctat attggcaatc
    72721 ctgattagtt ctggtgcact agggctttct gctttggctt cgatgaagga tgcgaaagac
    72781 atggatctat tgatgtttct taaagccggg ttcaatttcc tgcctgccgt tttagtgttt
    72841 atcggaatta gtggctttct attcggatgg cttcctcgaa tgggtaaact tgcttatatc
    72901 tacttagctt actcctttgc actcaattac tttggcggaa ttttggattt accagaatgg
    72961 ttttccaaaa cagctgtccc tagctgggtt ccacggatgc caaacgattc ttttgatctt
    73021 tccgtgttcc ttacgttatc atgtatcagc cttgcactgt tcgtccttgg ttctattggt
    73081 tataggcgaa gagacttact agaaggataa taaaaaagca tgtacaattt catgctagcc
    73141 tccaaatctg ggtcaaaaat ccaacatttg gaggtcattt ttttatttac aagtcttcta
    73201 actgctcttt atcaatgatc cagacttctc gattctttct ttttacataa ccattctcct
    73261 ctaataattt aaattttcta gataaagttt cgggggtcgt accgataaat gcagcaagtt
    73321 ctttcatttt cattggcagg aaaaagtgat ccttccctgt cgctttagct aagtcaagca
    73381 gatagacagc gactcgttct tctacttttt ccatcatcaa aaaagttgtc tgctgctgta
    73441 cttttgttaa tttctcaacg ttgattgcta aaagtttcag actaagggcg ggataatgca
    73501 gtaagagttc cgagaaatct ttttgtctca atatgcaaat ttccgttttt tctagtgctt
    73561 cgccaaataa agactcattt ggaacgccta gcaactggct ctctccctca tatccgcccg
    73621 gctctattac tcgtaaaagc tgttcctttc cgctagcaga taattgatac actttcatac
    73681 tgccggaggc cacgatcact aattgaggtt ctccattcgg cgcaagaatc tgttctcctt
    73741 tttccacata gtgatgtttg acaagtgcgt gtactttttc ttgatcttgc tgtactaagt
    73801 gattgaacaa aggaacaaat gaaacacata aatgatcatg actcataatc tctcctcctt
    73861 ctaaacagct atttctaata aagaaacata acttccctta ttccaactga taattttctt
    73921 ttatcatagc ataaacgtca agcgaaccag ataccagcaa atagagtgga tttctttttg
    73981 tcccttgctt tattttcctt cttttgagac cttaagtaat tgattcctat caatttttta
    74041 aatatttact ttttgaataa tcaaaaacaa accttcactc gcaagccgag agtaaggttt
    74101 gtttttcgca ttgcttattt cgtgttgtct attgaaattt ttccgcacct agcttttgat
    74161 atagtggtgc tagttcttgt aaggtttcag cggttatttg ctcaacgtgt tcgatttctt
    74221 gcggatagaa gaatagttta cccatttgaa aggttcggtc tctcatcgct tttttcaact
    74281 cttcttgttt ctttgtatcg gacaaatagt cagacaaagc taagtggtcg tcaagttcat
    74341 gttctggttg cggccatatg taataatcct tgatatcgac tgttttgctc cactctttca
    74401 gtatcgcaag caactggtta tacgctgcaa tgctaccata tcgttcttcg cttttataat
    74461 gttggtacat caaatagatt tggtattgtt tttgattcaa caaaactgct agacaggcat
    74521 tctcgtcttg acgagattcg cttcggtacg cgctccaaaa atgactgcgt aaattccagc
    74581 cattcgtcca gctttcgatt ttaggtttgc tcatgccgta catatcaggc aaaagtgcag
    74641 ctgtctggag ctgaatctct ttccattttt gccagtgttc tttatattct ttcttgattt
    74701 gttcaatctt atctgttgga tggctctctt tgagctgttt gaatgcgtag attggtcgat
    74761 caaacaactg ataatctgat tttccaagtt ccattgtttc gcctctttcc gttatctttt
    74821 gtattctacc tgaattttgc gatatggaca aatagaggtt gtgaaaaagc tgttctgcat
    74881 caagtcataa gaacagccaa acaaaaaact gcgatgagca tcaccgcagt tttattgaac
    74941 ttaaggttga ttgatcacat ctaaaagcgt tgaaaataaa atggcactag aagcagctcc
    75001 tgggtcgata tgtccgattg cacgctctcc tagataggaa gctcgtcctt ttttagctac
    75061 caagactttg gtgtgttctt ttgcctggtc aatgatttct tttgttaaat tccctgcctt
    75121 caatgcctct gtgactggca gccaaacatc taacatcgtt ttatcgtcag cttctgcctt
    75181 tcctcggctt tgaatacccg ctgttccctg ctcgatcact tcgcctaatt tttcttgaga
    75241 atcaatagaa tcgacctctt ttgtcgcttt catcatgttc atgaatgcag atccgtataa
    75301 cggaccagaa gccccaccga ctttcgatat catcgccata gagaatactt tgaatgtatc
    75361 gctgattgtt tcaggatgat cggcttgaaa agcttcttca taagctgaaa cccctcttcc
    75421 catgttattt ccatggtctc catcgccaat cggggtatct agatcactga gatattgttt
    75481 gttctgattg attgcctctg caaattgcgt gagccattct tggatttctt gaacggttag
    75541 tttcatatta tcaccctttt atcttgagat tttttaccat gaaatcgtct gtacattgct
    75601 ttctaaagaa tctttccatt gtgtctccgt caagtcgatc agtgttagag aaagaccttg
    75661 catatctagt gaggtcataa aattaccgac ttttcggaaa actacattga cgcctctttc
    75721 ttccaacaga gctaaaacat cattcatgaa cacgaactgt tccatcaaag gcgtcccgcc
    75781 cattccgttg actagtacac ctgcttcttt tggtaaattc gagtaatcat ctaaaatctt
    75841 agtaacaagt tcctttgcca gtactttaga aggctgcatc ttttctcgac gatagcctgg
    75901 ctcaccgtgg ataccaacac catactcgat ctcatcttct cctagttcga atcctggttt
    75961 ccctacttct ggtacagttg ctgctcgaag cgctagaccg atcgtcttag ttgcctgtac
    76021 gaccttttct cccagttctt tcaactcagc tagggaagca ccgtttcttg ctgcatcgcc
    76081 cacgattttg tgtacaagga cagtacctgc aactccgcgt tttccagcag tatacgtact
    76141 attttcaacg gcgatatcat catctacgat cacactttct acttcaatat cgtccatagc
    76201 agctaattcc tttgccatat cgaagttcaa tgcatcccct gtataattct taacgatcag
    76261 caaaactcct tttccactat ccgcttcctt aatagccgtc tgaatctgat ctggagttgg
    76321 agaagtaaac acatcaccaa gcaccgctgc acttaacatc ccttccccta caaacccggc
    76381 atgggatggt tcatgtccgc ttcctccacc agaaaccaaa ccaacttgtt ccgctttctg
    76441 attcttggct acaacacggg aagattctac acgatgaaca agttctggat agctttttac
    76501 taatccttcc agcatttctt cgacaatatt gcttggatca ttcatgattt ttttcaattt
    76561 attcccatcc tttctttccg gcattttgtg cttctgttaa gatttgctga gtatcatctg
    76621 ttataccggc agtgatggct gctgcaaaag ctccttccac taaaggcgca tccaccagat
    76681 gataacgttg ctgctgctct tcttccaaca tgtcttttgc cagttccgag ttcaataccg
    76741 cgctaccgat atccgcaaaa acaaaataac tagctgcatc gcttgattca ttgactgctt
    76801 ctacgatttt catcgggtct gatccgatct cgccatttat tccgccgaga gaaaaaattt
    76861 gcacctcttc ggatttttgc atctgctcaa tcatttcttt aataccatct gttacttttt
    76921 gactatgaga aataagcaaa atactttttt tcacaagaat cttcctttct tttacatagt
    76981 tgctaacgat tggtttcgct ttcattaatg aacaattcaa gtatataata aatttctaat
    77041 tttgggaaaa tatgtgtagt gcttcttgaa gtttgttata ctttaattaa aagagaggag
    77101 tgatcgaatg attacaacaa caacgaacag tgtagaggga aaagccgtag tagcttataa
    77161 agggatcgtt tttggtgagg tcattactgg aatccatgca tttaaagact tggaggcggg
    77221 gttgcgaaat atctttggcg gccgctcaaa aagctatgaa aacgaactaa tgggtgcaag
    77281 agaagaagca cttgccgaaa tggccgaacg tgcaaaagca ttaggagctg atgcgatcat
    77341 tggcgtaaaa atggactatg aagtattagg cagcgacaat ggcatgctga tggtcacatg
    77401 tagtggaaca gctgtctcca cgagataagt aggggacatc tgttttaata actaaagaga
    77461 gatgggacat gtagtggcac tcaagaatta gatttttcag tctaacttcg aggtactcta
    77521 ccttcccatc ctctcttttt tatttctttt tgcggatgat tccgtaagct gctgcgacta
    77581 acacacccgc ccctgctaag gaataactga cagaagctgt tttttcattt gtttttggca
    77641 aagtctgact tgttgatttg gatggctctg tcgtttgctg aactgtttct gtcgtgcttc
    77701 cagaggtcac tgatttttct cctgccgaat gcaaaatatc ttttattcgt tggaaactag
    77761 ctgctaagtc agcttttttt gcttcaaaat cattagcaac tgtttgtgct tcgctgatct
    77821 ttccgtggat tgcttgactg gccgctgtga tatccgcttg agtttgactt agctttccag
    77881 aagctgtttg agcaacctga tttaattgct gattgaattc ttttgcttgt tggatcttcc
    77941 cgtcaagatc tgtttggaca gcttccgctt ttgctttcgc ttcggcaagc tttttctcaa
    78001 gttgtgcacg gtcatttccc actttatttt taagatcagc taaatcttga tcgattgctg
    78061 cttggtcttc tttcaatttg ttttttgcag cttctaatgc ttcttcgagt tcttttcttt
    78121 tattttccaa gtcttgcaaa tgatcgattt ggtcagaaga ggtagaacta tttattgatg
    78181 tatcttctga agatgaaatc gtttctcctg aattatctgt cggtacattg gaagtcattt
    78241 ctgtttccga ggcaccgttt tcagcaccag aagagcttat agttgttgaa ggttctgttt
    78301 gagcaggttc agaagtttcc gcaaaagctg tctgtcccaa taagaaaata ctggaaacag
    78361 caattggcca gattaacggc ttcattcttt ttttcatcac ttttcccatc cttactactt
    78421 tttaactaat ttcttattat aagcaaaaat gtttggaaga accataaaca caacaggctg
    78481 tttgtctaaa aaacggtgca tcttttattt ttttgtacgt tccgggcttt tccatgtccc
    78541 gcttccataa cctaaaatcg ttttgactgc tggaatgaaa gtcgtcacga tcgttatcgc
    78601 gttcactatc cagaacaaaa gcatatatag tggtgcgaaa agaaggtatt tcaattttct
    78661 tcgtcgatca tctacaatca gcgaagctag caactggaaa aatcctgcga ccatttcaaa
    78721 gcagatgaac acaaaactga atgtaaaagt aatataaatc tgttcgtagt ttccttgata
    78781 tacataatgc ccgattaatc cagcaaaaag aactacggaa atacaaaaga atattgacca
    78841 gacaatactc aatgtttgat caatgaagat gatcgttctt ccaatatgtt taaaaggatg
    78901 gagcatcact tttttgaaat tcgtcagcca gacttctgtt ccaccttttg cccaacgttt
    78961 tctttgtcga tatagcatct tcaacgtcac aggtacttcc atgaaaaaga taatctcagg
    79021 agcaaaaaca gataaccagt catttaactg atgatcccaa gcaatactga tgtcttctgt
    79081 cgctcgatct tgtctgaatc cgcccacatc gatcaaggct tcttttcgat acatcgtatt
    79141 tgctccactg tacgcataaa gaccaccgaa aacagctgac tgtgttcgtt taatgatgcc
    79201 cacgatactt gagaattcaa ccgtttgaga ttttgcaatc aatttggtac gattttggac
    79261 atccatattt gcagtgaccg cagcaatatg tcttgcacca gggcgaatga aataattcac
    79321 atacctaatc agtgcatctg gctccggtac cgtgtctgca tcattgctta aaatcaattt
    79381 cccttttgca aaggcaagtc cgatattaaa cgcgtgggct tttcctttat ttttttcgat
    79441 ccgaaccaca cgaagattag cgtatttttt catcagtcta gctaatattt ctggtgtttg
    79501 gtccgttgaa ccatcgtctg tcactaatac ctcatagttg tgataattca atttcgtcat
    79561 caaatactcg attgtatctt cgatcacaat ttcttcatta tgggctggca ccatgatcgt
    79621 gatgaacggt tcgacactca agggaacatc tacccattct ttttgcttat gtttgtataa
    79681 aaacacataa caccagacac caataaacca tacaaatccg cctaaaatcg gataagaaac
    79741 gagaaaaaat acataataga caaacaagta tctaagaata aattacctgt atgggtgatt
    79801 gagatcattt cagttccacc ccattttctt tatacaaatc tgcaatgaat gtcgtatcta
    79861 gatttttctc ttcggagaca gaataaaaac ggaccgtttc tctctcttct tttgttccaa
    79921 aacgttccgt atacacttct tcaagtaatt cttgtctttt tttcaatttt tcatcttcat
    79981 attcaaaaga tttatttact tttttgtata gatttcgatt gttccaccta gtcaatacaa
    80041 atgaggtaat caggaaactg aaaaaaatca atacaaaaaa gccgattaag aaatacagca
    80101 ttttcttttc tgataaaaaa gcgtacaagg aaaaatcctt ggctctttct ggtctcgtta
    80161 atgggaaaaa gacccatata aaaggaagaa caacgatcat ccatcctaaa agagccacta
    80221 acgtttgcca aatctttaac cagtaattac cttttgaaaa atacttatct ttcaccaaaa
    80281 ttgatgcaac ttcttctctt gttacttttt tcatatcctc acctcacgtt tttttgttac
    80341 gacgtaggag tttaccatac atttcatttc ttttcacata aagtgttcct aaatttttcc
    80401 taagaaaaag aacaaaacat ttctcatcag taaatgaaaa atattttgtt ctttttatca
    80461 gttgttcttt ttatttttta tctcttaatt atgttgctct ttccaatacg acaatgcttt
    80521 tcattcctct agatatcgcc gtgtacattt gtctgcgtct tctttgctca tctccatcgt
    80581 tttcaaatgg atataagatt acatgatcaa attccagtcc ttttgctaga ctcaaaggaa
    80641 tgatttggca gttttctaat ccatatgaat tttttttaat cgattcttgt agcgtttggg
    80701 tttcctcttc tgtttgggtg ataactgccg ctttttctcc ttttagagaa accaaaatct
    80761 cagctagtat tttcaacaat tcttcagagg atcgaaaaga gcggtattcg ggttcttttc
    80821 cttgcggtcg gatcgatacg atgtcgatct tctcttgatc cacagcatag gttttgaaaa
    80881 gctctgtgat tgctccgcta gaacggtaac tatttctaag atcataccga tggatcggca
    80941 gatggtagtc gtcgaaacaa cgcataatat cagcaaaagt agtggaagaa ttaaagattg
    81001 cctgattctc gtcacctact aaagtaaagt gagtttttgg aaataattcg atcaatagac
    81061 ctaattgtgc cagggtataa tcttgtactt catcaatcaa tagatagcga aatgctggta
    81121 catttacctt ttcaacaagt aaatgacgaa tagctaatat aatgactgct tcatcaacag
    81181 tacgtgtggg ttgccaagca taagctgagc catatcgttt ttcataaatt ctttcaaaca
    81241 actgatgctc atccacccat gccatttctt cgatttgtct ggttattttt cgatattttt
    81301 tttgtaaaag tttccttgca taagctacaa tactttgttc cgaatcatca gaaatcaatt
    81361 taccgaataa ttccaactgc ctatcttctg tcaacgagag tacctgattc tgcacagcag
    81421 gactttttgc ttgtttcaaa agatgattct tccattcgct catcagtgcc tttttcgttg
    81481 cttgaagcct atcgatcaat ttaggatgag caggaacttt ctcatatatt ttttcgatcg
    81541 tttttttaga aaggactgtt tttccatttt tagtaagtcc acggataaaa ttcggatgat
    81601 ctaaaaacaa aggatctgat tgttttagat tatcgataaa ctttttgcta cgcaaacgtt
    81661 ctgtctgctc cgatacattt tctcccgtga tacgtttgaa ataagcctct tcaccttcta
    81721 tttcctctgc tgaaagctgt gaaaccagct gtatgatggt tagattcagt ggatttcttt
    81781 cacctaatga tggtaggaca ttcgaaatat agtcgataaa ccgatgatta ggtgatagaa
    81841 tcagcaagtc atcggatgtc atcgtatctc gatataaata gagcagatac gcaatacgct
    81901 gcatgatagc agaggtttta ccacttcctg ctacgccatt taccaagata ttttgacttt
    81961 tcacatcccg aatgattgtg ttttgttccg attggatcgt agcagtgata gccttcattt
    82021 cattggtctc atcttggcct aagacttcta ataatacgtc atcttgaata gctacagacg
    82081 tatcaaaaaa cttgaccaaa cgatctcttt ccaaaagaaa ttgtcgtctt tctttaataa
    82141 ccgtatcgat tttattttga cgaaccgtat aagaagatgg accaatcatg ttattgtaaa
    82201 aaagttcggc aattggtgaa cgccaatcat aaacaagatt ttcatctgca tcatctgtga
    82261 aatttgctgt accgatataa aaggattctt ttggctcatt atccagaaag tctacaacga
    82321 cttttccaaa gtagggactt ttcaataaac gttcgatctt tgctagctga ttttctgcgt
    82381 ttttctgttt gatattcatc tgatcgattt ctctattttt catttcaatc atcgaaaaag
    82441 tatccaggtt atctaagtaa ctgtcaaaat tcaatcgaag ctcgccagcc atttctttca
    82501 acgactggtt tccttctatt tttgccgtat ccatcgattc ccgcagttcg ttttttttat
    82561 caattagctt ttgatacacg ttcttcagat atgcttcttc taactgtttt tgtgtgttga
    82621 ccatacacat tctcctcttt ttttaaagtg gtggaaccga ttagtttacc tcttttaaga
    82681 gtcgaatgca agctttttaa cgagtatcat ttgttaggat atatcagttc ttcaggtcgg
    82741 acagtttgat ataaagaaaa tgcaccatca aggtttttta cgtggtagcc agactgcttc
    82801 aagattcttt ccgctagata gctacgtaat ccgctatgac agctgacgat atattcttgt
    82861 tggctgtcta attcatttaa tcggtcccga agttcattca aagggatatg tttggcttcc
    82921 ttgaatttgc ccttttccaa ttcttctgct gttcgcacat ctaataaaat ttttcctttt
    82981 gctagttctg tcggcaattc atgccattgt acggtttcac taagcccttc tgcaatgttc
    83041 attgctgcat atcctagcat gtttactgga tctttggctg agccaaatgg cggtgcatac
    83101 gtcaattcta attccggtaa atcgaagatc gtcaaatgcc ctttgattgc tgttgctaaa
    83161 atatcgatcc gtttatccac accttttgcc ccaacacctt gtgcaccata aatctcgcca
    83221 gtctctggat ggaagatcaa cttcagtaaa atatctgttg cttctggata atagcttgca
    83281 tgatcttttc ctgatacatg aatgacttca aaagacagtt cgttttcttt ggctgttctt
    83341 tcacttaaac cggtggatgc ggcagtcatt ccaaacgttc gtataattgc tgttccaata
    83401 ccgccttgat ttcttcgaga aattccggaa atcgtgtccg caacttgtct accttgacga
    83461 ttggctggtg aagcaagaga aataagtgca tcttttccag tgatttgctg ttttacaacg
    83521 atagcatccc ccaccgcata aatatcagga atattcgttt gataacgttc gtctactagg
    83581 atacccccgc gtatgcctaa ttcgattcca gcggtcactg ctagctggtt atcaggacga
    83641 acaccaatgg ataaaataac taaatcagca gggatggtac gcccatcatc cagtcgcaat
    83701 cgtttcccgt ggtcttcaaa tccagcgaca gcatgagaag taatcacttc tactccttga
    83761 tgagacaatt ctttttctat aaaagctgcc atttcttcat ccagtgttgg aagaatatgt
    83821 ggtgcttgtt cgatcaccat gacttctaaa cctcttcttt ttaggttttc tgccatttcc
    83881 aatccgatga atcctgcacc aacgatcacg gcacgctttg gctgtttttc taatgcatgc
    83941 atcactttat cgatatctgg tacatttcta atagaaaaaa cattgtcggc ttctgttatc
    84001 cctggaatcg atggaacaac tggttttgca ccaggagata aaaccaatgc atcgtactgt
    84061 tcaatgtgtt tttgaccctc atgtacgact tctaccgttt tgttttcggg aaagatggct
    84121 gtcacttcat gatttggacg cacatctaaa caaaaacgag cggataatga ttctggcgtt
    84181 tggacaagaa gattttcccg ttcactgatt tctcccgaaa gataataagg caagccgcaa
    84241 tttgcaaaag aaacatacgg tcctttttca aaaacaacga tttctgcatc ttccattaat
    84301 cggcgaagcc gtgtagcagc agacattcca cctgctacac ctccgacaat aacgattttc
    84361 atcttatttc cctcctactg ttcgatcaaa ccattgattc atgccaccac gtacattcac
    84421 tacatcataa ccagatttct ttaattcttt agctgcttgt ttactcctca tccctgattg
    84481 acaaatcaca tagacggtct tttctttgtc tccatcatat ctgtttatac tttgtaatgg
    84541 aacattttta gctcctttta tatgcccgcc ccggtattct gcaggtgttc taacatcaag
    84601 taacgctgga ttttccaaaa gcttttcctt taattctggg actgttatcg attttattga
    84661 ttgaaatagc aaattcattt tctgcacctc atttacattt ttataaatac ctcatggggt
    84721 atattaaaca ggagctttat taatatgtca accagaatga ctcttcattt ttttcactac
    84781 tttttatatt tgcataaaat accgataagg ggtattatct aattataaaa atagaggaga
    84841 atgtgttatg gagattgata ataaaaatat cctgaaccgt ttgaaacgta cagagggaca
    84901 aattcgtggt atccaaaaaa tgatcgaaga cgaaaaagaa tgtatggatg tcatcactca
    84961 attaagcgct gttcgttcta gtattgatcg cgtaatgggc atgatcgttg cagataatct
    85021 gaaaaattgc tttgagaaac ctgatagtaa tccagaagaa caagcggcta aactagaaca
    85081 agcgatcaag atgattatta aaaagtaaag gaatgatttc aatgaaagtc gttttccata
    85141 ttgatgaatt agaaaaatgg tcagaaacag ggaaaaacgt aaaaaacctg ataaaagctt
    85201 ctccagaaac gacgattgtc gtatctgtaa atggcatcgc gattaccggt tatctagact
    85261 ctgccaatgc agaattctta gatttgcaag gagtcgtttt tcacgcttgc gccaatgcta
    85321 tgcgtgctaa tcatatttca gaaagttctt tacctgaaca agtaatcgtt gtaccagcag
    85381 gtgtccttga tttagttgaa ctgcaatccc aaggttatgc ttatatcaag ccttagtcag
    85441 tagaggttgc gacagaagtg atcagcttca agaaatttcg gcttattttt cgaagaagct
    85501 acttctggaa aaccgtgaat caaaggttgt gaaaacgctg tcctgcatca agtaataaga
    85561 acagccaaac aaaaatagct tctcatattt ttcgtttggt tgggcttatt accgcagatg
    85621 caagcttttg aacaccgttt aaggaagagg ttgtgaaatc agcggtttga cctaagtatt
    85681 agagaaaaaa acgggaaaat agctcctcat attttgccgt tttttgagct aataccgaag
    85741 gtcagctgat tgaacaccgt ttaaggaaga gattgtgaaa aagtcgctta gtttcgagta
    85801 ttaagaaaaa ttttgtgaaa atggatttct acatttttgc ataaatttgg cttaataccg
    85861 agaaactggc ttttgaatac cgtttaagga agaggttgta aaatcagcgg tttgacctga
    85921 gtattagaga aacaaacgga aaaatagctg ctcatatttt gccgtttttt gagctaatac
    85981 cgaaggtcag ctgattgaac accgtttacc aagaggttgt gagcctacca tttaactccg
    86041 aatcacaaga aataatttca aaaacaactt ctcctgtttt tggtttggtt ggcttattat
    86101 cgagaagtag ctactgggag tctatttatc aaaaaaagga atgcgacata ggtcacaccc
    86161 cttttttatt ttctttgaaa catctttcgg tactcgacag catacaagac aaaagattgt
    86221 aaaagaccgt aagtgatgac ggcaaaaatg actctcaccc acagcgttgg taattctggg
    86281 aaaagcagca aaaggatcat gccaacatag atgacagcag tcgctacttt gccataccac
    86341 ttcgctccac ttaatttgat atttttagat agcccgatta atccagctac aaacataaag
    86401 ccttctttta tcaagaatag accaaacaac agccaaagcc acggtcgata ccatgccata
    86461 gacaaaatca gaaaaagttg tgtcaattta tctgcaaacg gatcaagcac cttccctaag
    86521 tctgttacct gattatatct ccgagcaatg accccgtcta gataatcaga caaacctgag
    86581 acaacaatga ccgctcctgc tatataaaat gactgtctca gcacaaaata aagataaatc
    86641 ggcagcaaaa aaatacggaa tatcgataaa agattcggaa tcgtttgtat ttctttacgc
    86701 cagtctgtgc ttaatttcat tttatcgccc tacctcctca gcactctttt ctttttattt
    86761 tagcttacac ggggaataaa accaatgatt tcactgtttt tatttttctt tacagccact
    86821 gatattatga gctaatttga gataatcact tgctgttttc atcgtttact cttctttctt
    86881 cctgtcgttt gcgcatttct tttaatagta ctttatgagc tttttttgat cctcgctcta
    86941 ggtcacgctg ccgtttacgt gttttataat cgataaacag actgtctaaa tcgtaacctg
    87001 tcgggtacag atcttctgct gaacgcacca gacgaacacg ctgacgaggc acgtggatta
    87061 tttttttgtc taaatataca tcaatcgtat cttcacctat atcttcataa actaacgctt
    87121 ctttttggta ttcattgaca aatatccgat caccttttgc aaagagctgg cgttcttttt
    87181 tattctcctt cctatttgta actgctgtct taggaagaaa ttcttttttc tgtgtccgat
    87241 aggctttttc cgccaagtaa cgctctgctt gatggatcaa tttcatcgac atatccattt
    87301 tatgagcaat ccacaaagct tggctttctc ctgtttctcc aacccgcaac tgatatttag
    87361 gacgaagtgc ttcccgatcg aaagccatag cagccggcac aaaatcttca tgatctccgg
    87421 cgaatttctt gatttctcca taatgggtcg tggcaatgat caatgcccct tgctcataca
    87481 tagattccat gattgcgatc gctagtgcag ccccttcatt tggctctgtt ccactgccaa
    87541 tctcatctaa aagtaccaac gtattccttt ttatcttttt caaaatagca gcgatgtttt
    87601 gcatatgacc agaaaatgta ctcaacgcat tttctaaatt ttggtggtca ccgacatcga
    87661 cgaaaatctc atcaaagaca gcaagctctg tcccttcttt tgccggaact tgcataccga
    87721 acatcgccat caaagtcaat aaaccgactg tcttcaacac gactgttttg cctccggcat
    87781 ttgctccggt gataatcaag cctcgatagt ctttaccgat ttcaacatcc aatggtaccg
    87841 catgctcagg taaaaatgga tgtctgcctt gcttgataat gatatgttcc gatttattga
    87901 ttctaggtgt gcttccattg atttctcggc taaattttgc ccgagcaaag atgatatcta
    87961 acaccgtgat cgtttcgatc aataaatcga tcacttcttc gttttctgcg atagcaccag
    88021 tcaatgccgc caggacttga tattcttcac tgatttcttc agcttttaac aactgatagt
    88081 gttcattcaa tttagaaatc acagttggtt caataaaaac cgtcgttctt ttatttgatt
    88141 catcgataat cgttccatct attttatttt tatagctggc tttgatagga atcgtatagt
    88201 attcgccttt ttgaacaatc attgcttctt ggatcatttc tttgtttttc ggatgacgca
    88261 agaatttcag taattttgac tggatttctt tttcgattag ttgtaattgt ttgcgtactt
    88321 tacgcaaatt acgtgacgcg tcgtcactga ctttattatt ttttattttc tggtcaatca
    88381 actcttctac atttatcaaa tcaggaagat gtttgctata agcaaacaac aagggtgtct
    88441 ggtattgatt cttatcaaaa aactttgtga tcatccgact gcttctaaga aaatccgcat
    88501 attcgatcaa atcggttggc tgcagaatca accctttttt gacttgttct gtcagtgcat
    88561 cgatcctcgg caaccccata aatggaacat gctgactgct ttctaagatc aagcgtgctt
    88621 ctcttgtttc ttcttgacga tccaagacag tttgtaggtt tgtcgagacc gtcatatcgc
    88681 tgattcgttt tttgctatag tttccaattg ctcttgcttg gatttccttt ttgatccgat
    88741 caaattgtaa ttgactaatc atttcgttgt ccatattctc tccttttctt gaagagatac
    88801 ctgtcccaaa ataaataagg gcctagagat aaataaaagg atagaacaca gcttaaaaaa
    88861 gtcatgtcct atccttatta gaatacaaag atattgtttt cctgacaggt accgtttcat
    88921 aagcacacca aataaacttt gtttattggc tattcgactt actgattaga taccagctac
    88981 actcacaaaa cataccccat tcttctaggt cttatttatt ttccacttaa ctatagcaag
    89041 acacattttg gttgtcaaac tttagtatgt tttatagatt tacaccatta atgaatagac
    89101 acctaccgcg ataattgctc cgatcattgg acctgcgatt ggtacccatg aatatgccca
    89161 atctgaagtt cctttattag ctattggcaa taccgcatgt gctaatcgag gaccaaagtc
    89221 ccgagcaggg ttgattgcat atcctgttgg ccctcctaat gaaagaccga tggctaagat
    89281 caatccacct acagcgaata cgttcgttcc aggtgcaaat tcgttttgtc caaaagctag
    89341 caacccaaga actaatacaa atgtaccaat taattctgtg atcacatttg ctggataatt
    89401 ccgtatagca ggacctgttg caaacgttcc taaaatcgcg ctttcatctt tcgttgcatt
    89461 ccaatgtggc aaataagaaa gccaaacaag aatggcccct gcaaaagctc ctaaaacttg
    89521 cgcaatgatg aaaggaacga caagattcca actaattgcc cctgtcatcg ccatagctag
    89581 agagactgca ggattcaaat gagctgggcc catgaatcca gaaatataga cagccattgt
    89641 tacagcgagt ccccaaccaa atgcgatgac aatccagcca gaagcctgtg ctttactttt
    89701 gtttaaattc acagccgcac acacaccatc tccaagcaaa actaggatca gtgtcccaat
    89761 aaactccccc atgatttgag tcatatcact gttcatttat ttctccccct ttagttcccg
    89821 cagatctgat tctgcaatca atgcttctaa acgtttagtc tgttgcgcct tctcctcttc
    89881 tgtccattca aaatatccag caattgcatc gatcacaggt tgcttgatct catcaagctg
    89941 atctcgttca aacaacagat gatttgtacg acgaatgaga taatcgcctg gggccaaaac
    90001 catttcttct tctaaaccat aacgtaaccg agctgactca gcgagactca aaccaggata
    90061 aggtgccatt tcttttgcta attcaaagat acgtcgggca ttagtcccgt aaaaatcagc
    90121 gatataagta gcatcttctt cctctaaacc ggctgctact ccttcttttg ctaattctgt
    90181 cactgtttct tctaatttag ttggatcgaa gtttccacct gaaatctgat attttttaga
    90241 gtcgatttct ttcgtctcta ttccgtattc ttcttttaat aattggcgta tcaatcgcaa
    90301 agctccttct gccatcttac ggtaatcggt gattttccca ccagataaag tcagcaaacc
    90361 atctggttct ctttctaaag aactacctct ggaaatcgta gaaggtgctt tttcatcacg
    90421 gctgttttcc aaatggttca acacgtcttc tacttcagca cgagaaactt tgttttcctt
    90481 atattcactt actgtatcga caactttatt gaagctcttg tctgaaatcg atccattatc
    90541 tccaccattg taatcagaac cagaattacc aatcaacagt ggacgaagtc ctgcccagct
    90601 tgcttcgata tcattcaatg tgatatttgc ttctggatag cgatgattga tcacatccaa
    90661 tagataatct acatcttctt gtgtgacttt cggatccgta aaatctcctt ggtaatccgt
    90721 atctgtcgta ccaaagtaag tcttgttttc tcttggaata gcaaaaacca tccgcccatc
    90781 ttgctttcct gtatcgaagt atgtgggttg cggtacaggc agttttttcg catctacaac
    90841 taaatggatc cctttagttg gacgcatttt aggagagact ggacgcgtaa aattcaagtt
    90901 tcgtacttta tctacccaag gaccactcgt attgatcact aattttgctt tgatttcgat
    90961 cacttcatct gtcagcaggt cacgagcttt gacgccaacg atttgatcgc catcatataa
    91021 aaagccaacc gctttcattt tacttactag ataagcccca tcttcggcag cctttttgat
    91081 attatcaatc actaaacggg catcattgtt gcggaaatct agatagacac ccgcgccttt
    91141 tagcccttct tttttcaaaa acggttctct ttccaatact tcttctggtg tcagcgtata
    91201 attctcatat ttggttcctg tcacatttgc cagtttgtca taaaggtcca ttgctacttt
    91261 gaccgagaac atattgaagg ttgttgctcc ttcgccctca tagattggca aaagcattgg
    91321 atctggtttt gggatgtgtg gggcaatact ttgtacgact gcacgttcac caactgtgtc
    91381 agctactact tccacatcaa atgtcttcag ataacgaata ccgccatgaa caagtttggt
    91441 cgagcgagag gaagtccctt ctgcaaaatc ctgcatttcg atcaatcctg ttttgattcc
    91501 tgatgctgct gactggactg ccacaccggc accagtgatt ccgccaccga tgatcaacag
    91561 atccaattct tcttgctgca ttttttgaat gctatcttgt cttgtcttgt ttgaaaacat
    91621 atggatttcc tccttattca aatgcttggg tagcttttac tgcttttttc caaccgttgt
    91681 aaagtttttc tcggcgctct tcctccattt gaacttcaaa tagcttgcca gcttcataaa
    91741 attcgcggat ctcgtctgta tctttccaat aaccgacagc taatcctgct aaaaatgctg
    91801 cccctagcgc cgttgtttcc aagttttctg ctcgttggat cggtacattc aagatatctg
    91861 tttggaattg catcagatat tcattgtttg ctgcaccgcc atctactttc aatacaggaa
    91921 tcttgattcc agtgtcatct tgcatcgtat cgatgatatc tctcacttga taagcaatcg
    91981 actgtaaagt agctttaatg atatcttctt ttgtcgtacc acgtgtcaag ccaaacatag
    92041 cccctcgtgc tgcctgatcc caataaggag cacctagccc aacgaatgca ggaacaacat
    92101 aaacctcatc ttcgcttgta gagcgtttcg ctgcgtcttc tgaatcgcta gctttttgca
    92161 acatttgaag tccatctctc agccattgaa tcgaagaacc agccacaaaa atacttcctt
    92221 ctaaagcata gtaaaccttt ccatttatgc cgtaaccaat tgtcgtcaat aaattatttt
    92281 tggataattg cggtttttca ccggtattca tgacaataaa tgaacctgta ccataagtat
    92341 tcttgaccat gcctggttcg aatgccattt gtccgaataa tgcggcttgc tggtctcctg
    92401 ccatccctga aattggtgct tcgcttccat aaaaatgata accttgcgta taaccataaa
    92461 cttctgagtt agaagtgact tttggtaaca tcactcgagg aatatttagt aaatctaaaa
    92521 tctcctgatc ccaatctagc tgatggatat tgaacaacat cgtccgactg gcattcgagt
    92581 aatcagtaac atgtgcttgt ccatcggtca gtttccatac taaccaagaa tcgatcgttc
    92641 caaacatcaa ttcgcctttt tcagctcgtt cttgcgcgcc ttctacatga tcaagaatcc
    92701 agcgtatctt cgttgctgag aaataggcat cgatcactaa ccctgttttt tcgtggaaaa
    92761 attcttgata gccttcattt tttaagttat ctgcaattcc agctgactgt ctggattgcc
    92821 aaacaactgc atgatagatt ggacgtcctg tatctttttc ccatattact gttgtttcac
    92881 gctggttcgt tatgccaatc ccagcaatct gatttggttt gatccctgat tcgatgaacg
    92941 ctccggcaat aactgactgt acagaattcc agatttcatt tgcatcatgt tccacccaac
    93001 tttcttgcgg gaaatattgc gtgaactctt tttgagaact gccgatgtgt cttcctttct
    93061 tgtcaaagat aattgctcgt gagctagttg taccttggtc aatcgccatg atatacgttg
    93121 attctgtcat tgtgattccc tccattatat gcaaacgctt tctttaacta ctcttatcat
    93181 actactgttt taaaaaaaga aactgtcaaa attttattct ttttttcttt ttttgacagt
    93241 tttttattat gaagctattt tttaatcaat tcttttcttt tttcagcgtc tctattcttc
    93301 ttttcaatcg aataatgtcg taaggtgacg caaattctga cagataatat tcacactgtt
    93361 ttttgtttct ctggcaaaat gtgatcacca aatcatattc tttaccttct tcataacttc
    93421 caatctcaat accgccgatt cccctcagtt ctctgatcag atattgttga aaagcaatac
    93481 gataaatcgg cagactttct aaatcgattc caatcactac tggttttgca atataaaaat
    93541 cgatcatcaa aagaacattg gcatactgga tcatcaggta actaagctca ctatcttcag
    93601 ctcttttcct cggcaattgc tgcaccgctg tttcctgtaa tttcgccagt aactgtgtta
    93661 aggaatgccc gagcattttc tgctgctgtt ccaaaagccg atcacgctca tagacttcga
    93721 tctttccaac aaagaaaaac cattcattgt tgatctggga aatttggtag cctactgcct
    93781 tttcttcttt gattttcaaa cgacgaggac gataatgcca taacatcgtt tcccgaatgt
    93841 aagtatctaa aacagcggtt ggtaactttt tgctccgtgt caaatcatac tgataaaata
    93901 tttcttcgtc tactatcgaa aaagaaacaa aaaagctgta aaacatcatt gtttcgtata
    93961 cattcagttc tgctgctgtt cgactaagat gcatcacgat gattggatcg attgcttgat
    94021 aaagccggtc cgactgatag agtaatttct tttctttcaa agttgcgtac gtactttttt
    94081 cattcaatag tctttttttc gtaatcccga gccagcaagc aatctgtgct tctgctgatg
    94141 ccgtaaacgt tgtttctaat acacggtcca atcctagaat gaacggtctt ttttctggtg
    94201 tattttgcaa aaaaagcggt cgctgatctt ccgggatata ttggaatagt tcataataaa
    94261 aatatcgtat ctgtagctct tctccgtata attgaccgtt tttgatttgt aatccaaatt
    94321 cctctaagag ctggttcaat tctttgatct ttcgaaaaac agaagactca ctgatattaa
    94381 acgctgtcgc taatcgaacg atggatactt gctgatgttc taataaatag acgagcatct
    94441 taaacttcaa gctttcctgc aataaaaaca atagaatttt ttccaaactt acatcttcgt
    94501 ccaacacaag cagcgcctga tactcatttc gctgtacttc tacttttttt tccatcattc
    94561 ggccaatcaa ttcaatatct tccaaatatt gatcaaacga ggcttttgac agttggacat
    94621 gctctctcaa accattgata gaggctgttc ccccttgcag aacaaggttt cgcaaaatca
    94681 ggatctgtaa ctgctctttt ctttctaata atgcttcaat cttcataggc agtattcgcc
    94741 acctttgacc acaccatatc tggcacacgg tattctggct ggaaaaatag ctcatgttct
    94801 tctaactgtt caaacgtcca tccttctttt actgcaattg tcagttggtc aagaaggtgg
    94861 aacatctctt ttttgctttg gagctgtgct ccaagaatct ttttttcaga atcaaataga
    94921 aatttgagtt taactttgct ttgatttatt gctgtaagct tgtagtctac gtatcctgtt
    94981 tcaatttttt ggggataaaa aatgctctct tcttctgtca aacctacgct tcctaagaaa
    95041 tagccaaacc actgattgcc gactggacga taggttccct gatcctttgt ctgtgagcca
    95101 ctaattgtct tgctgacatt tcgtgctgta cggacagcgt tatttactag agaaacatac
    95161 attttttcat ttgttggacg aaaagttact tggatcgcat cgccaatcgc ataaacgtct
    95221 ttttgagacg tttgcaagta gtcatctacc cagatcgttc catcatcatt caatgttaat
    95281 tgttcttccc acatctgatt gtcggggcga gaatgattag ccagcaaaac aagatcatag
    95341 ttctcctttc ttttttccgt ctctacaata gcggtttcat tttcggtcaa agacacaact
    95401 tgttcttcta aaaaaagtga aagcccttga tttttcattt cctttactaa cggttctgtc
    95461 atttcaggat ctagataacg aaaaagaatt gactttcggc tttcgtaaag atggatttgt
    95521 ttttttcttg atgccaaccc ttcagctatt tcgattcctg cttgtcctgc accaataatt
    95581 gcaattttct ttgcattcat gatcttttgc tgaagagccg ttacgttttg tatcttttta
    95641 actgggtgaa taagcgttga ttctgcagaa atatttcgaa acttttgatt tgaaccagtc
    95701 gctagaatca aacgatcaaa atccaatttt tttcctcctg ctaaaacgac ttttttttct
    95761 ttcaatccta ttactgtctt ttctgtgtaa acatggattc gatagcggtc agtcagttct
    95821 tctttcgtga tccaagaaag ttgtttttca ctggtaacct ttccttttaa tatcaaattg
    95881 aacccgctgg gaatccatcc taacttcgat tgcttttcaa tcaaatatat ttcacttgtt
    95941 ggcatcaatt ggcgaagata aatagccgca tgaatccctg caaacgaccc gccgacaatt
    96001 acaatgttca tctgcattcc tctttcttat aaggtgttct actgctaact tctcaatcag
    96061 aaaacacagt attcataact cgctttcaac cttatgatac atagcgatgc agcagaatca
    96121 accctctcca tcataccgtg ttctaggtct gcttctcaat aatgtactag tggacctaat
    96181 tgaagagtat catttctgaa gagatgtttc aaaaaatgta ctcttataaa agaaaaaaac
    96241 tcgcctttta cgtacctctg tccaaatagg aaacagaaaa gaacgaaaag acgagtttta
    96301 gcgtgtgtaa tgtaatagtt agaatagaca catcatttat ttttaattct ttaatgcttc
    96361 aacaactgct tcgcctaatt gatgagcaga ttgaggattt tgccctgtaa gaagccgccc
    96421 atcaatttga accacttctg aaaaagctgc tccagactga tagtttgctc ctttttcttt
    96481 caaagcatct tctgctaaga atggtacttc attcgttgta ccatttgctt cctcttcttc
    96541 attactgaac ccagtcactg tacgtccagc taaaatagat tttccagact catctgtaac
    96601 tggcaacaat cctacaacac cgtgacaaac agctgagacc agcccttcat ttcgatagat
    96661 ttgtgaagcg actttcccaa gatctattgc ttctggaaaa tcccacattg ttccgtggcc
    96721 accagcataa taaaccgctg cataatcatt tgcatccaca tcatcaggac gtaaggtatt
    96781 tcccaaggcc cgatttctga aatcttcatc ttcataatag gcccaatcga tttcatccat
    96841 attcaaaaca ctttgcggtt ctaaaggtac atatccgcct ttaggactga caaaatctgc
    96901 atcgatccca ttttttacta atacatcata aaaatgagtc agttcactta accacaaacc
    96961 tgtaggacgc tcgatctttt cgtacttttc tacatttgtt aatacgatca atactttcat
    97021 tttcccatcc tctttctata aaaattgcgt tattgataac gtgctttcaa gaaattatat
    97081 aatgggcttg gcaaataaag ctctttatat gcttcttcaa aaggtttcgt tacaaattca
    97141 tcctcacggt tttccaataa tttctctgcc cagtcaggat cgacgatcat ttgctgtcca
    97201 attgctgcaa gttctgcata tttcaatacc tgctctacat cttcgcgatt gcggatccca
    97261 ccgacaccaa ctaaagggat ctttccttga atcgtgttat ggaccacttc aagaatcgat
    97321 ttatcgttgt atttatcaga acgagctatt cgatcataca tatttaatga aacatgcaga
    97381 taatctagtt ttgactcacg taatcgttca agaagccaga tcgtgtcttc aaaacggata
    97441 cctggtgttt catattcttc tggtgagaaa cgatacccta cgatgaatgg ttttttagca
    97501 tattgttcaa ccgctgagaa aaccgttgtt aataattctt caataaaacg ataacgattt
    97561 tccaagctac cgccccattg atcctctcgt ctattcgaat gcggagagaa aaattgttgg
    97621 atcaaatacg tatttgctcc atgcaactcg attccatcaa atcctgattc aatcgctcta
    97681 cgtgtggctt tgccaaatgc ttggattgtt tcaacgattt cttcttcact cattgctcgt
    97741 ggtgtttccg catcaggacg ttttgctgca actgcacttg cagatacagg ctgttctcca
    97801 gataaagttg ctcgacttgt cattcgtcca ccgtggaaaa tctgaataat cgcttttgcg
    97861 ccttctcctt ggattgcttt cgctagctca cttaatcgag gaatcatttc atcatgagcg
    97921 atgctgagtt cacctggcca gccttttccg atatcttgga catttgcagc accagtaata
    97981 acagcaccaa gacctttaga acgttgttta taataagtga tctcatcttc ggtgatcact
    98041 ccattgaaaa agctgagttg tgtcgtcata ggcgacagca tcaatcggtt cttcaattga
    98101 actcctgaag gtaaagtaat tgattgatca aattgtgaca ttgtcattcc tcccataatt
    98161 cgctctgatt aacctatcga gaatcatcta tcattaaacc actcgattag ttgtacatgc
    98221 aactaatttg cttaaaaaat tttatttttt ttgtaactta tctgttgcat cattcattgt
    98281 ctgggctaat tctttacttg cttcatttcc caaaactgct ttgtatgact gatgaagttc
    98341 ttcccagcta ccatcgactt ccttagcaaa ttggcgtcct tgttctgtaa gataaactaa
    98401 tgacaagcga ccttcgctaa ctgttttgac gtatccttta tattctaatt tttcaacaaa
    98461 acgagcaatc gttgatgggg cggaatagag catttgtgca atatcttttt gtggtattcc
    98521 atctttttct tttaatatca ataaaataaa accataagtt ggtgccagac ctgtccttct
    98581 aaacgcttca tcagctaatt tattcaacat gcgatctagc tttttcacgc taaagaaaag
    98641 acattcatct aacgcttttt caattggctt ttccatttca tcccctccat tggcgtacat
    98701 atcatagtat gatttttatt ttttgtcaaa aaacacggaa taatgtccgc ctcctctgtc
    98761 tagatttgaa aaaaagaagt agccatcttc aaagaatttc ggcttgtttt cgacaaaact
    98821 ccttctggaa caccgtgaat cagaggttgt gaaaaagtcg tttagttttg agtatgaaga
    98881 aaaattttgt gaaaatggct ttccacattt ttgcataaat ttggcttaat accgaaaaac
    98941 tggcttttga acaccgttta tatcagaggt tgtgaaaaag ccgtcctgca tcaagtaata
    99001 agaacagcca aacaaaaata gttcctcata ttttgtcgtt ttttgagcta atgccgatgg
    99061 tcagctgatt gtacaccgtt tattgagagg tcgtgagcct gccgttgaac tccgagtcac
    99121 aaggagcaat ttcaaaaaac agcttctcat gttttatgac tatggtgact tgtgatcgag
    99181 gagttggcag gagaatactg tttattcgta aagaaggggc tgtgacaaga cttttgtcac
    99241 agtcccttat ttccttttat tataggattt cgccatttga ttggatgact tgtctgtacc
    99301 aatcaaatga ttttttcttt aaccgtttct ttgtgccatt cccttcgtca tcttgatcaa
    99361 catagatata tccataacgt tttgacattt gtgaagtaga agcgctgacg atatcaatgc
    99421 agccccacga cgtataacca aataaatcta ctccatcttc gatagcttcc ttcatctgct
    99481 caatatgctg cttcaaatag tcaatgcggt aatcgtcttg aacggttcca tcttcttcta
    99541 ctttgtctat agctccgagt ccgttttcag ctatgaacag tggtttttga tacctatcat
    99601 ataattgatt caaagcaatt ctcaaaccct taggatcaat ctgccagccc cattcacttg
    99661 atggaagata cggattttta attcctccag ttattaagtt tccttggacc ccttccaaat
    99721 tttctggatg agcactgact gcactagaca tgtagtagct aaaagaaaca aaatcaacag
    99781 ggtaggctgc taagatttct tcatcaccta cttctatttt taagttgaca cctttttctt
    99841 caaacattcg ttgcgtatac gctggataat atcctcttgc ttgaacatca ctaaagaaca
    99901 aagaagttct ttgctgctca attgtttttt gaatatcatc cggatcacaa gaatacggaa
    99961 caagaagctg atagctgatc atacaaccga cttgtgaacc tttgataatt tcatgacaag
   100021 cttttgtagc taaagcactt gctataaact gatggtgtgc accttggtat ttcgcttgtt
   100081 ccaaatgggg atggttttct tcaattactc ctacgctaac aaaagggtga tgttttacac
   100141 agttgatctc attgaaagtc atccaatatt ttactttatt tttatagcgt ttgaatactg
   100201 tttcagcgaa acgaacgtaa aactgaataa gctttcgatt aggccatcca ccatattctg
   100261 taaccaaata taacggcatt tcataatggg aaagagaaac gactggctca atcccatatt
   100321 ttagacattc gtcaaacact tgatcataaa aaaataatcc cgcttcattg ggtgtttctt
   100381 catcaccatg aggaaaaatt cttgtccatg cgatagacat ccgatagcat ttaaaaccca
   100441 tttcagcaaa taaacggatg tcttctttaa agtgatgata gaaatcattt ccgtgtcttt
   100501 taggataata atacttgctg ttgggatcct gcgccgcttt tacttgctga tgcgtcatca
   100561 tatgccattg atctgtccat ttttctttag gtaaatcgct gtcgaatgta tacacatcag
   100621 acacagataa tcctttttca tctacatccc atgcaccttc acattgattg gccgctgtcg
   100681 ctccgcccca taaaaatcct tctggaaatt ttttcatatc gatcccccta aacttgctag
   100741 ttttcttgtt tgattatttt tcttatgact agtaatgata tttttgaatc tactactatt
   100801 tgtaacaata accattgtgg tcggatcata tccctctttg attaattctt gcaaatctac
   100861 ttccatcaat aaatcgcctt tacgtacttt ttttccatca gatactgcac tttgaaagta
   100921 tttgccattt aaattcactg tatcaatacc gatatggatc agtatctctg ctccttcttc
   100981 actgactacc ccaattgcat gtttcgttgg aaaaactgtt gaaacttccc cgtttacagg
   101041 actgtagatt tttccgtccg ttggaatgat cgcaaaccct tctcctaaag atccactagc
   101101 aaatgttgga tcgtttactt cagataaatc aattatttca cctgctgcag gagtacttaa
   101161 cactatatcc tttgaggatt cttcttcgat ttcatccttg tagccgaaaa gaaaagttag
   101221 catacaggaa ctgatcatcg ctaagaaata actagcaact agccaaacaa atccttcacc
   101281 aatataaatc gggaaagaca aaatacttct tgtagcaact gccaaagcac cggctcctgc
   101341 ggcaccagct actccaccaa atatagctcc acatatacaa gcaatgtaaa atggtcgttt
   101401 atatttaaga gtcacaccat aaacagcagg ttcagtgatt ccaaataatg ctgtgataaa
   101461 tgcagataaa gataaacttt ttactttctt atttttcgtt ttcaaaaata ccccaagtac
   101521 tgctcctgct tgcgcagcta cggcagtcat acatgctgga cctagcgtat cacgaccgta
   101581 gaaagaaaga ttgttggtca ttactggtac aagtccccaa tgtaacccaa aaatcactaa
   101641 cacttgccaa aatccgccga taacagcacc agataaaaca gggctaaagt tataaacagc
   101701 taaatatcca gctgcaatca gctgacttgc ataatctgca attggaccta caactaataa
   101761 agtaattggg accatcacga tgatacaaat gaatggtgtc aataaatttc gaatactttc
   101821 gtgcaagctt ttgcgaatct taggctcaat ataagaaaga acccatacag ctaaaattgc
   101881 tggaataacc gtacttgtat atcttgctag aatcacgggc atccctagaa atcgcaaggt
   101941 tatgctatca ctatatgcac tgacaatcgt aggataaacg agagctgctg caataaccat
   102001 agcgatgaaa cgatctgtat tgaacttttt tgcagcagta tatgccaaaa atataggcaa
   102061 gaaatagaaa aatgcatcag ctgctgcatt caaaatgata taagttcctg attcagtagt
   102121 taataaattc aaactcgtac ataaggcgag tactcctttg atcaaaccac ttcctgccaa
   102181 gacgcctaaa gtcggggcaa aaacagcggc gatcatgtct ataaaagagt ttaaaatgcc
   102241 ttttttctca gttcctctct ttccactaga tgcatcatct tctagtttca tttgtttgga
   102301 taatacgtca tacacttcat ttactgcatt tcctactacg acttgaaaca ttcctccagc
   102361 ttcgactaca gtgatcacac cttctagttg ctctaccttc tccttatctg ccttcttatt
   102421 atcttttagg gtaaagcgta accttgttgc acaatggtaa acattgctga cattttcttc
   102481 gcctccgaca aatcggacaa tatctttcgc taattgtgaa tagtccattt ttacttcccc
   102541 cttgttaatt aatgccgtag caatccttct tacaagataa gtatagttct tagaaaacgg
   102601 tttctccatt caattagtac cccttctaat agcgaacgaa actgtacaat agtgtgtatg
   102661 gtttacttag ccgagcaaat cactcactgc ttgaaagaaa acaagtatat cgtttctctt
   102721 atagtcaaag gagacaaaaa aaacacgctt gatcttcctt tgctgatgta taagtggtat
   102781 ctcaagctga tactctgtga tttttgtttc tacttggctt ttgataagac agcacaacaa
   102841 agtctcggca tttaacggaa gcataactag gtcagaacta ggagagatta gttgctgaat
   102901 ggaatctatc tttttatgga tttttatttg attttcttct ttgtagtaat gatcaagcag
   102961 ttttgttttc tttttttctt caactatggt cagcttttca cgcaaaatct gataaatctc
   103021 cgaagattca aactcatcta gaacactagg tagataaatc aaatcatccc actcaaaaat
   103081 aagctcttgc tcagtagtca aaattgcatc atattccgtt attttgtttg attgattttt
   103141 gaaaagatac actggttcta tccggcattc tttgatccac atgttcatac tttgttgaat
   103201 ctgttttttt agtgtattca aaatactaat tggctggtta ctaacaatca gtatctcccc
   103261 ttgttttcga aaaggattca acgcttcggc aagatacaaa accaaataag cgctttcagc
   103321 taaattggga cgtaattgaa aatgtattgg gaagaaacgc cgaattaaat aaatttctaa
   103381 aggataacgg gagatgatct tttgtacaaa atgattcatg gtattatgtc cggcatccat
   103441 cctcgttttc atttgtttga tatgggttag caaaaattct gtttcatgga acaataacga
   103501 aacaggaaga tctaaaaaac gaataatcgt ttgctcaaat gctcttagat tcttctctat
   103561 ttctttgttt ttttcatcat taatcatcaa ataatttaac tctaatagtc gattttcaat
   103621 tgcttgtttt tcttgattgg aaaaagaata gggtagttct gatgataact tttttgtgag
   103681 ggtctctacc atcggaataa ataatgtata cctgtttgtt ttttctaaaa gttcttctct
   103741 tcgaagaatg gtcaaaacga gataccgaga aaatcgtatg aagtcctctc ctgaaacaat
   103801 ataattatat gatataagaa cctcttttaa tgtcttttgg acagtcggca tgatattgga
   103861 aaaaattgta ctgatttgtt gaggcaacct tgcgtgttgg atcaccgttt ctgttccaac
   103921 aagagataag aaaattcttt ttgaattttc ttcagcaatg atttttagtc cttttgtcga
   103981 cgaaacttcc agttctaatt taggattgcg ctcgatccaa cgcaaaatcg tttttatttg
   104041 taatgatacg gctgtttttg aaagaaagaa aatgtctgct atcttttgca tactgacata
   104101 ccctttttga aacaataagt acgtcacaat agttgaagct cggaaatcca tgctggaata
   104161 gattttatgt ttcgtcacct cttgtatgat ttgctgttta gtttcagatt caattgattc
   104221 taaaaaataa cctgaacgtt tatttgactg gataatgatt ttcttctcgt agatagcaag
   104281 catatttttg atttcagttt ggatcgtttt cttgttggta cctaaagctt cagctaattc
   104341 ttcgcttgtt atccaatgat tcttatttct taatactaca agaatttgga gttgtcgttt
   104401 atttaagtcc atttgcttac acctcctctt tgttataaac atacaggaaa aacctctcaa
   104461 atgacaatag tcacttgcag aggtttaaaa atcatttgaa gaaagatcta tattcaaggt
   104521 ttttaccatt agactggata atttgtttat aatattcaaa actatctttt ttcaatctcc
   104581 taaagcttcc gctcccatca ttttgtctat ccacataaat aaagccatat cgcttcctca
   104641 tttcccctgt tcctgccgat acgatatcga ttggtcccca ccataagtaa ccaatgattt
   104701 ggcaaccatc ttttattgcc tcagcaattt cctgaagatg tatttttaga tactcacaac
   104761 gttttggatc gtggattcga ttcaattcat ctggtgcttc atctagtcca atgccatttt
   104821 caactatgaa taatggtaat tcataacggt ctgtcaattc attcatgaca taacgaaacc
   104881 ctagaggatc aattggccaa ctccaaggtt cgggagattt ttccttcaaa aagggattat
   104941 cgaaaccatt tgctccgcca gtatctacgc gcatttctgc ttctttttta tagacagcgc
   105001 tacgataata actaaatgca atataatcta ccgtgttagc ttgcaagtac tgttcgtctc
   105061 catctaacat tactggtgca cagtcttctt ccttccatat cctgtaaata taagctggat
   105121 aatgccctcg gcacatgaca tcggagaaaa accatgaatt gcgtttaaat tgcagtgaac
   105181 caaatacatt ctctggatca cagtcatatg cataagtcgc taatgcagaa aagctacaca
   105241 taatacccat cttagcattt ggatcgattt tctttaataa ttgagtagca cgggcgttcg
   105301 ctagaaacat atgatgacag gcttgataaa tctctttttt tgttagtgta gcaatgggtt
   105361 caagtttatc tctagcaggg aatgtaacca atccagcagc tgcataaggc atacgaaaag
   105421 cattattgat ctcattaaag gtcatccaat atttcacttt cccttggtag cgttcaaaga
   105481 cggtctgcgc ataaaattca aaaaagtcga ttaattttcg attttgccac cccccatact
   105541 ctcctaccaa tgctaagggg gtttcataat gactaagagt aattactggc tcgatatcat
   105601 atcgatttaa tgtattgatt agtctgtcat aaaatacgag accagcctca tttggcttct
   105661 gttcgtctcc tcttggaaat attcgtgccc atgagatgct tgttcgaaaa gcttttaaac
   105721 ctaactcctt cagtaaacga atatcctctt caaatcgatg ataaaaatca atcgcttcat
   105781 gagaaagata atggagtgat tcgtctaaag caatctccca aatctttttt tcttcattcc
   105841 actgaatact aggatgctgg ttcatgatcc cgataagcgt atctgtcaca ttaggtaatt
   105901 tgccgtcttc caaccatgca ccttcacatt gattagcagc tactgctccg ccccataaaa
   105961 aattttctgg aaatatttcc tgatccataa ctatctctcc tcgctatcaa caatttctta
   106021 cttgaagtat agctcgattc atcaaaacaa gatattctaa ctatttcggc agaagagaag
   106081 aaaaaaattg aatgctactc ttcattttta atatttatat ataacaaata cataagacga
   106141 tccccgaaag aaaacactcg ttaaccatct aagcaaacga tttattttac ttccaacaca
   106201 aatgcttcat aaggtcgtaa atcaactttg ccgtctggta actgtttcag aggataattt
   106261 gacacaataa cccttaaagc ttcacgtgga acagtgaacg tctgcttttc actggacata
   106321 ttacaaataa cgagccattg ctggtcttca tatatgcgag aataggcaaa gacatgctca
   106381 ggcgtctttt ccactaattc atagtctccc cagacgatga tgtcatgttt tctacgcaaa
   106441 tcgatcaatt tcttgtacat ataaaaaaca gaatcttgat ctgctaacgc ttcttctgca
   106501 ttgatttctt tataatttgg attgactcga agccatggaa ttccagtagt aaacccagca
   106561 tgttcacggg cgttccattg cataggcgtc ctagcattgt ctcttccttt cgcattgatt
   106621 gattccaaga tttcctcttt tgtaaatcca gaagaaatcc tttcgttata catattgatt
   106681 gtctcaatat cttttgcttc cgcgatatca tcgattgggc aattcgtcat gcctaactct
   106741 tctccttgat agatataagg ggtgcctttc atcatatgga gcaagatagc aaacatcttg
   106801 gcactttctt ttcgatacac atcgtcattt ccccaacgag aaacaattcg cggaagatcg
   106861 tgattattcc aaaataaact attccatcct tcatcaccta aagatgtttg ccatttggat
   106921 aatacttttt tcagttcaga gatactcaag ggtttcaaat cccatttgtc tttgccttct
   106981 tgctgatcta atcctatgtg ttcgaattgg aagaccatgg ataattcatt tcttttagga
   107041 ttggaataaa gtttagcgat ttcggtagtt gctccccatg tttcgccaac agtcatcaga
   107101 tttttgtcac caaaagttgc ttgattcatt tcctgaagat actcatgcag tttaggtcca
   107161 ttacttgtga tttctttatc cggttctttg ccaatcatat cgatcacgtc catacgaaag
   107221 ccaccaatac ctttatcgat ccagaaattc atcatttgat aaatctcttg gcgaacctgt
   107281 ttatttttcc aattcaaatc aggttgacgc ttgctataca agtgcagaaa atattgcccc
   107341 gttttttcat ccaactgcca agcagaacca ctgaatattg agcgcaatct attaggctct
   107401 tttccattga ccggatcacg ccaaatataa tagtcccgat aaggattttc tttattttta
   107461 cgggcctcaa tgaaccacgg atgttcatca gaagtatgat tcaccaccag atccatgatg
   107521 atacggatat ttcttttctt tgcttcttca atcagttctt ccatttcttc catcgtaccg
   107581 aattctgcca tgattgcttg ataattactg atatcatacc cattgtcatc attcggagac
   107641 tcgtatactg gagaaagcca aattgcatca atacctaaat acgccagata atccaacctg
   107701 gaaataatcc cccgcaaatc tccaatacca tcttgatttg aatcttgaaa acttcttgga
   107761 tagatttgat aaacaactga atggtgccac catttttgtt ccatgatttt cctcctataa
   107821 atggatgttt ctattttttg cttaatcatt tattttagtc tctctcacta aaaattgtaa
   107881 cgctttcaaa tagctattgc accttgttat cggtaacaga ataaaacaaa aaaacagctg
   107941 aggaaattcc ctcaactgtt ttttgaaagg attgatttat tcagggaaga atgctgattt
   108001 cacaacttct ttataaacgg tgttcactca gctgtccctc ggtattagct caaaaaacgg
   108061 caaaatataa gaaactattt ttttcgtttt tttctctaat actcaggcca gaacactgat
   108121 ttcacaacct ctttataaac ggtgttcact cagctgtccc ttggtattag ctcaaaaaac
   108181 ggcaaaatat gaggaactat tttttcgttt ttttctctaa tactcaggcc agaacactga
   108241 tttcacaacc tctttatttc acattcaata tccacatgaa tcccatgaat acaaagaaca
   108301 gaccatacat gatgggagat acttcttttc ctcttttagc tgctaacatg gtaattggat
   108361 agaagataaa acctaatgca atcccatctg aaatactata agtcaaaggc atgccgatca
   108421 agatcaagaa tgaagggatc gcaatctcta agtttcccca ttcgatttgt cgcaaagatt
   108481 gtgccatcaa tactcctacc ataatcaatg ctggtgcagt tacttgtgaa gtaacaactg
   108541 atagtaatgg agaaaagaac aagcctaaca agaagaaaat ccctgtagta atagctgtga
   108601 tacctgaacg tcctccaacg gcgataccag ctgatgattc tacaaatgca ccaacaggag
   108661 aagtacctaa taaggaaccc gcaagcatag ctgttgaatc agaagctaaa gctttcccta
   108721 cacgaggcat cttgttgtct ttcatgaaac ctgcttggtt tgctaatcca actaaagttc
   108781 ctgctgtatc aaagaaagtc acaagcaaga atgtcagcac tacgacccac atttgaagag
   108841 aattgatgtc ccctacatgt tttaatgcaa ctaaaaatgt tggtttcaaa cttggtgctg
   108901 cggcaacaat ttcagaaggc attggaatca aacctgtgac cagacctaaa atcgttgtag
   108961 ctgccatccc gatgaagatg ccacctggta cacgccgaac aagcaagata gcagttacga
   109021 ctaatccaaa aatcgtcaac caagtagaac caacgttgag tgatcctaat cctactaatg
   109081 tagattcatt cgaaacgatg atcccacctt cgctcagacc aaggaaagca ataaatagac
   109141 cgataccgcc agaaatcgca tatttcaaat ctgctgggat cgcatcaatg atcatttccc
   109201 gcagcttgaa gattgtgatc aaaataaaaa tcaaagaagc aacgaatacg ccggctaatg
   109261 ctgtttccca tggaatcccc attcctaaac aaacagaata agcaaaaaaa gcattgatcc
   109321 caagagcagg tgccgttcca attggataac gggctaatac ccccattaaa atacagccga
   109381 tcgcactggc taatgcagtc gcagtaaaca ctgctccttc atccattcca gaagcaccta
   109441 atacagttgg atttacaaat aagatataag ccattgagat aaatgttgta aatcctgcca
   109501 gtacctcacg ttttaccgtg gtgttcaatt tttctatttc gaagtaggaa agtatttttt
   109561 ccttcatctt ccatccccct aaatccgaac attataaata aagtccgtta aaatttcgat
   109621 ttattaataa aacaacgtgt tttatcatat actaaaacaa aacataagta aacaaaaaat
   109681 tcggatttta agcaaaatcc gaacgttcca tctgattaaa tccctttatc tcaaagttca
   109741 tgaacattca ctttggatta caagaatttc tttattgtgt taataaagtt tcttcattct
   109801 agtctcaaaa atcaatagtg tgatttgatt ttaccatttc gtttctgttc ttctttgatg
   109861 aattcttttg tatcgacagg attcagatta tttagtccgc caaaacctgt atcgaccatt
   109921 tttccccagc cttttgtctt cttttttcct gatttgagat tctttgctcg aagcttctca
   109981 ctatgttttg ctcgccgata cttcaaataa ccttctaatc ttcccattag atccactgtt
   110041 tctcctcctt tttattcaat cagacgactc agcttttcct ataacaaaat aattgccttc
   110101 agggtccgaa aaattgaaag tcaagacgcc attgttgtct gtgatttctc ctggttcttc
   110161 catgttctcg tagatagttt caaattcatc cgtaaaaaat actaaagaag gcggtggtcc
   110221 taatacctct ggtgaaaact tctgcacaaa tacttttggg aatacgccta attctaattc
   110281 ttttgagatg ctgagtacaa tactcttaaa ttcttctggc aattcgattg tttcagaaat
   110341 ttctgcacca attttttcta caaagaatcg gcaaatcatc tctacgtcat tgacataaag
   110401 catcacacgt gttttttgta tcatcgtttg acccttcttt ctatttgatt ttctttcctg
   110461 tctataaact gattccatta tatcacgaaa gcgcaaacac cttgtgtttg atactattca
   110521 agaaaaataa agcaatagtt tctaggattg ctttcctcca caaacttttt tta
//
LOCUS       DAPBCF010000004        99767 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.004, whole genome shotgun sequence.
ACCESSION   DAPBCF010000004 DAPBCF010000000
VERSION     DAPBCF010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 99767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 99767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..99767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.004"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(552..2165)
                     /locus_tag="RD508_000318"
     CDS             complement(552..2165)
                     /locus_tag="RD508_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7734951.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2306..3214)
                     /locus_tag="RD508_000319"
     CDS             complement(2306..3214)
                     /locus_tag="RD508_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7734952.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHRSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3397..4521
                     /locus_tag="RD508_000320"
     CDS             3397..4521
                     /locus_tag="RD508_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7734953.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4748..5665
                     /locus_tag="RD508_000321"
     CDS             4748..5665
                     /locus_tag="RD508_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7734954.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5658..6491
                     /locus_tag="RD508_000322"
     CDS             5658..6491
                     /locus_tag="RD508_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7734955.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6574..7692
                     /locus_tag="RD508_000323"
     CDS             6574..7692
                     /locus_tag="RD508_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDT7734956.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7686..9584
                     /locus_tag="RD508_000324"
     CDS             7686..9584
                     /locus_tag="RD508_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HDT7734957.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9578..10801
                     /locus_tag="RD508_000325"
     CDS             9578..10801
                     /locus_tag="RD508_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDT7734958.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10887..12821)
                     /locus_tag="RD508_000326"
     CDS             complement(10887..12821)
                     /locus_tag="RD508_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7734959.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13047..13703
                     /locus_tag="RD508_000327"
     CDS             13047..13703
                     /locus_tag="RD508_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDT7734960.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13777..14130)
                     /locus_tag="RD508_000328"
     CDS             complement(13777..14130)
                     /locus_tag="RD508_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDT7734961.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14322..15251
                     /locus_tag="RD508_000329"
     CDS             14322..15251
                     /locus_tag="RD508_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDT7734962.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15262..16098
                     /locus_tag="RD508_000330"
     CDS             15262..16098
                     /locus_tag="RD508_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HDT7734963.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16346..17122
                     /locus_tag="RD508_000331"
     CDS             16346..17122
                     /locus_tag="RD508_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7734964.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17298..18041
                     /locus_tag="RD508_000332"
     CDS             17298..18041
                     /locus_tag="RD508_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7734965.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18034..19614
                     /locus_tag="RD508_000333"
     CDS             18034..19614
                     /locus_tag="RD508_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HDT7734966.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19865..20344)
                     /locus_tag="RD508_000334"
     CDS             complement(19865..20344)
                     /locus_tag="RD508_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDT7734967.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20360..21112)
                     /locus_tag="RD508_000335"
     CDS             complement(20360..21112)
                     /locus_tag="RD508_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDT7734968.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21229..21299
                     /locus_tag="RD508_000336"
     tRNA            21229..21299
                     /locus_tag="RD508_000336"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21261..21263,aa:Gly,seq:ccc)
     gene            21660..22385
                     /locus_tag="RD508_000337"
     CDS             21660..22385
                     /locus_tag="RD508_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HDT7734969.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22640..22906
                     /locus_tag="RD508_000338"
     CDS             22640..22906
                     /locus_tag="RD508_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HDT7734970.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22903..23334
                     /gene="ruvX"
                     /locus_tag="RD508_000339"
     CDS             22903..23334
                     /gene="ruvX"
                     /locus_tag="RD508_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDT7734971.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23359..23664
                     /locus_tag="RD508_000340"
     CDS             23359..23664
                     /locus_tag="RD508_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HDT7734972.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23745..24890)
                     /locus_tag="RD508_000341"
     CDS             complement(23745..24890)
                     /locus_tag="RD508_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7734973.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24951..25598)
                     /locus_tag="RD508_000342"
     CDS             complement(24951..25598)
                     /locus_tag="RD508_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7734974.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25792..26085
                     /locus_tag="RD508_000343"
     CDS             25792..26085
                     /locus_tag="RD508_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734975.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26129..26440
                     /locus_tag="RD508_000344"
     CDS             26129..26440
                     /locus_tag="RD508_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734976.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26437..27061
                     /locus_tag="RD508_000345"
                     /pseudo
     CDS             26437..27061
                     /locus_tag="RD508_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27202..27360
                     /locus_tag="RD508_000346"
     CDS             27202..27360
                     /locus_tag="RD508_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734977.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27361..27723
                     /locus_tag="RD508_000347"
     CDS             27361..27723
                     /locus_tag="RD508_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734978.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27760..28608
                     /locus_tag="RD508_000348"
     CDS             27760..28608
                     /locus_tag="RD508_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HDT7734979.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28598..30073
                     /locus_tag="RD508_000349"
     CDS             28598..30073
                     /locus_tag="RD508_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HDT7734980.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30339..30746
                     /locus_tag="RD508_000350"
     CDS             30339..30746
                     /locus_tag="RD508_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HDT7734981.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30749..30964
                     /locus_tag="RD508_000351"
     CDS             30749..30964
                     /locus_tag="RD508_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734982.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30968..31348
                     /locus_tag="RD508_000352"
     CDS             30968..31348
                     /locus_tag="RD508_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDT7734983.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31482..31637
                     /locus_tag="RD508_000353"
     CDS             31482..31637
                     /locus_tag="RD508_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HDT7734984.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31706..32179
                     /locus_tag="RD508_000354"
     CDS             31706..32179
                     /locus_tag="RD508_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HDT7734985.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32176..33870
                     /locus_tag="RD508_000355"
     CDS             32176..33870
                     /locus_tag="RD508_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDT7734986.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33836..34021
                     /locus_tag="RD508_000356"
     CDS             33836..34021
                     /locus_tag="RD508_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734987.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34025..35200
                     /locus_tag="RD508_000357"
     CDS             34025..35200
                     /locus_tag="RD508_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDT7734988.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35193..36716
                     /locus_tag="RD508_000358"
     CDS             35193..36716
                     /locus_tag="RD508_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDT7734989.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36772..37056
                     /locus_tag="RD508_000359"
     CDS             36772..37056
                     /locus_tag="RD508_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HDT7734990.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37043..37378
                     /locus_tag="RD508_000360"
     CDS             37043..37378
                     /locus_tag="RD508_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDT7734991.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37673..38299
                     /locus_tag="RD508_000361"
     CDS             37673..38299
                     /locus_tag="RD508_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7734992.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39041..39877
                     /locus_tag="RD508_000362"
     CDS             39041..39877
                     /locus_tag="RD508_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDT7734993.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39942..40376
                     /locus_tag="RD508_000363"
     CDS             39942..40376
                     /locus_tag="RD508_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7734994.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(40444..41766)
                     /locus_tag="RD508_000364"
     CDS             complement(40444..41766)
                     /locus_tag="RD508_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HDT7734995.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41920..43560)
                     /locus_tag="RD508_000365"
     CDS             complement(41920..43560)
                     /locus_tag="RD508_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HDT7734996.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43890..44360
                     /locus_tag="RD508_000366"
     CDS             43890..44360
                     /locus_tag="RD508_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HDT7734997.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            44989..46092
                     /locus_tag="RD508_000367"
     CDS             44989..46092
                     /locus_tag="RD508_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDT7734998.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            46376..47056
                     /locus_tag="RD508_000368"
     CDS             46376..47056
                     /locus_tag="RD508_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HDT7734999.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            47146..48180
                     /locus_tag="RD508_000369"
     CDS             47146..48180
                     /locus_tag="RD508_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HDT7735000.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            48194..48529
                     /locus_tag="RD508_000370"
     CDS             48194..48529
                     /locus_tag="RD508_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735001.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48513..50993
                     /locus_tag="RD508_000371"
     CDS             48513..50993
                     /locus_tag="RD508_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735002.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            51049..52608
                     /locus_tag="RD508_000372"
     CDS             51049..52608
                     /locus_tag="RD508_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7735003.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52605..53969
                     /locus_tag="RD508_000373"
     CDS             52605..53969
                     /locus_tag="RD508_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7735004.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            54140..55210
                     /locus_tag="RD508_000374"
     CDS             54140..55210
                     /locus_tag="RD508_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7735005.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            55225..55893
                     /locus_tag="RD508_000375"
     CDS             55225..55893
                     /locus_tag="RD508_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7735006.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55913..56491
                     /locus_tag="RD508_000376"
     CDS             55913..56491
                     /locus_tag="RD508_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7735007.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56894..57805
                     /locus_tag="RD508_000377"
     CDS             56894..57805
                     /locus_tag="RD508_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7735008.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(58061..58978)
                     /locus_tag="RD508_000378"
     CDS             complement(58061..58978)
                     /locus_tag="RD508_000378"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HDT7735009.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            59180..59617
                     /gene="zapA"
                     /locus_tag="RD508_000379"
     CDS             59180..59617
                     /gene="zapA"
                     /locus_tag="RD508_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDT7735010.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59675..60223
                     /locus_tag="RD508_000380"
     CDS             59675..60223
                     /locus_tag="RD508_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HDT7735011.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            60338..62698
                     /locus_tag="RD508_000381"
     CDS             60338..62698
                     /locus_tag="RD508_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDT7735012.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62785..63099
                     /gene="trxA"
                     /locus_tag="RD508_000382"
     CDS             62785..63099
                     /gene="trxA"
                     /locus_tag="RD508_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDT7735013.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            63281..65059
                     /gene="uvrC"
                     /locus_tag="RD508_000383"
     CDS             63281..65059
                     /gene="uvrC"
                     /locus_tag="RD508_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDT7735014.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            65204..66103
                     /locus_tag="RD508_000384"
     CDS             65204..66103
                     /locus_tag="RD508_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7735015.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            66096..67358
                     /locus_tag="RD508_000385"
     CDS             66096..67358
                     /locus_tag="RD508_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7735016.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            67519..69417
                     /locus_tag="RD508_000386"
     CDS             67519..69417
                     /locus_tag="RD508_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HDT7735017.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(69716..70435)
                     /locus_tag="RD508_000387"
     CDS             complement(69716..70435)
                     /locus_tag="RD508_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDT7735018.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            70772..71104
                     /locus_tag="RD508_000388"
     CDS             70772..71104
                     /locus_tag="RD508_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735019.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            71091..73094
                     /locus_tag="RD508_000389"
     CDS             71091..73094
                     /locus_tag="RD508_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HDT7735020.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            73113..73583
                     /locus_tag="RD508_000390"
     CDS             73113..73583
                     /locus_tag="RD508_000390"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HDT7735021.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73604..74188
                     /locus_tag="RD508_000391"
     CDS             73604..74188
                     /locus_tag="RD508_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HDT7735022.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            74203..75189
                     /locus_tag="RD508_000392"
     CDS             74203..75189
                     /locus_tag="RD508_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HDT7735023.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            75179..75490
                     /locus_tag="RD508_000393"
     CDS             75179..75490
                     /locus_tag="RD508_000393"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HDT7735024.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            75512..77293
                     /locus_tag="RD508_000394"
     CDS             75512..77293
                     /locus_tag="RD508_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HDT7735025.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            77286..78662
                     /locus_tag="RD508_000395"
     CDS             77286..78662
                     /locus_tag="RD508_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HDT7735026.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78669..79304
                     /locus_tag="RD508_000396"
     CDS             78669..79304
                     /locus_tag="RD508_000396"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HDT7735027.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            79334..80689
                     /locus_tag="RD508_000397"
     CDS             79334..80689
                     /locus_tag="RD508_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HDT7735028.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKITIHSKIALTVTGTLLLGGFVVFFFTERNGETLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80881..82275)
                     /locus_tag="RD508_000398"
     CDS             complement(80881..82275)
                     /locus_tag="RD508_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDT7735029.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQKLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQNKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            82367..83338
                     /locus_tag="RD508_000399"
     CDS             82367..83338
                     /locus_tag="RD508_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HDT7735030.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKDKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSATLTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            83335..84116
                     /locus_tag="RD508_000400"
                     /pseudo
     CDS             83335..84116
                     /locus_tag="RD508_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
     gene            complement(84285..84656)
                     /locus_tag="RD508_000401"
     CDS             complement(84285..84656)
                     /locus_tag="RD508_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7735031.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TTPSYYFVIDPDGYKIEVIRG"
     gene            84790..85233
                     /locus_tag="RD508_000402"
     CDS             84790..85233
                     /locus_tag="RD508_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDT7735032.1"
                     /translation="MDKPIFGEKKQSANYQTRYAAYIVIERDKRIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(85276..86085)
                     /gene="yidA"
                     /locus_tag="RD508_000403"
     CDS             complement(85276..86085)
                     /gene="yidA"
                     /locus_tag="RD508_000403"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDT7735033.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(86104..87471)
                     /locus_tag="RD508_000404"
     CDS             complement(86104..87471)
                     /locus_tag="RD508_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7735034.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHKVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(87455..88285)
                     /locus_tag="RD508_000405"
     CDS             complement(87455..88285)
                     /locus_tag="RD508_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDT7735035.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            88448..88885
                     /locus_tag="RD508_000406"
     CDS             88448..88885
                     /locus_tag="RD508_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HDT7735036.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88961..89581
                     /locus_tag="RD508_000407"
     CDS             88961..89581
                     /locus_tag="RD508_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HDT7735037.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     EKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89770..90276
                     /locus_tag="RD508_000408"
     CDS             89770..90276
                     /locus_tag="RD508_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HDT7735038.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            90293..91192
                     /locus_tag="RD508_000409"
     CDS             90293..91192
                     /locus_tag="RD508_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDT7735039.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKARR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            91279..92164
                     /locus_tag="RD508_000410"
                     /pseudo
     CDS             91279..92164
                     /locus_tag="RD508_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
     gene            complement(92356..92427)
                     /locus_tag="RD508_000411"
     tRNA            complement(92356..92427)
                     /locus_tag="RD508_000411"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(92392..92394),aa:Arg,seq:ccg)
     gene            92487..93821
                     /gene="rpoN"
                     /locus_tag="RD508_000412"
     CDS             92487..93821
                     /gene="rpoN"
                     /locus_tag="RD508_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDT7735040.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            93970..95061
                     /locus_tag="RD508_000413"
     CDS             93970..95061
                     /locus_tag="RD508_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HDT7735041.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            95102..96103
                     /gene="gap"
                     /locus_tag="RD508_000414"
     CDS             95102..96103
                     /gene="gap"
                     /locus_tag="RD508_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDT7735042.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            96213..97403
                     /locus_tag="RD508_000415"
     CDS             96213..97403
                     /locus_tag="RD508_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDT7735043.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            97507..98262
                     /locus_tag="RD508_000416"
     CDS             97507..98262
                     /locus_tag="RD508_000416"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDT7735044.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            98378..99676
                     /gene="eno"
                     /locus_tag="RD508_000417"
     CDS             98378..99676
                     /gene="eno"
                     /locus_tag="RD508_000417"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDT7735045.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        33099 a        17048 c        20558 g        29062 t
ORIGIN      
        1 ttaaataaat aggaacaaaa aaattaaatt atttaataca cacattaggg atcattcatt
       61 gaaggattag aagacaacga ggatggcgaa aaatatgatt acaatagaaa agtcgttcta
      121 aaccaatcag ttcctagtat cacacaacgc aagccagtcg atttggtgag attagaggag
      181 tgaaagcaaa ctttattata taagaaaaaa tattcgaaag ggatgctagt ttaggtacta
      241 gtgctgatag attaatatga tgcctcgtaa tattaggcgt agttactcta gagacatcac
      301 tatggactat gatttgtctc agagtcacaa catgtttttt tatgaaaaga aacagctaaa
      361 ataattaaat tgcgcaatgt ttaaactttc ttaaactata acctaataaa tgtgaagaaa
      421 taatgcacaa tttcttcaca tttatcttct attctatata cataccaacc aacaacccta
      481 tatacttttt catttttact cctcaagtaa aaataactcc tagaccgcgg ctacccaccg
      541 cggtcgtttt tttattcttc aatcaaaatc gctttgatac ccaaacctgc caagattcgg
      601 gcagaagtat aagtattcaa tcctcttctg aaagtaatgt aaactttttt atcttttggg
      661 atttcattga ttcgatctcg taactcattc attggaatat tttttgttgc cgagatactg
      721 ccagaaggtg ctttattagg ttcacgtata tctaaaaaga acgcttcttt caaatcgttt
      781 tcgggtatat cacttgcttt gatcgtttct acgatattcg tcatttgatt gattgcgaca
      841 taaccagcta tattcaacgg gtcacgggta gtagaatacg gtggagagta aggcaactcc
      901 aaatcaggca aatcaaagac tgtcaagttt ccggtgattg ctacagaaag ttctcccatc
      961 cgtttatcga cacctttttc tccaaatgct tgtccaccta aaatacgacc gctatctgca
     1021 tcaaaaatca gctttagatt taatcttgta gcttctggat agaaataggc atggtcaaag
     1081 ggagtgataa aaacagtttt ataatttgtt atgcctgatg cttttaattc atgttctgtc
     1141 attcccgcat aacttgctgt atgatcaaag atttttgcga cacctgcacc aatatatccg
     1201 cgatagcgca taggcgtacc atttaaaata tctgccagca tatgtccttg acgattggcc
     1261 gcactggaaa gcatactttg gatcggctga ccagtcacta cactagtcgt ttcgataata
     1321 tcgccaatcg catagatgtc cggcagattg gtttgtaact ggtcatcaac aatgatctga
     1381 cctgtatctg ataattgtat gccggttgct ttcaccactt cattcttcgg agaaacacca
     1441 acagcaaaaa ttagcatatc agcagaaagg acggagccat ctgataatac tatttctcga
     1501 cctttatcac ggatctcagt aactcttgtt tctaaatgaa cggctaatcc ttctttcagc
     1561 aatttgtcat aaactaaatt agcaatttct ggatcataag ggaaagcgac ttgtggcaat
     1621 tgatcgatta aagtcacgtc taagccgcga tgcttgaaat tctcagctaa ttccagaccc
     1681 ataacacctg caccaagaat gacgacatgt tgtggatttt tttcttcaag gaacgatttg
     1741 attcgatccg catccgtcac actacggagg acaaagccgt tttctgcttc aaaaactccg
     1801 ggaatatccg gataatctgg tctagcacca gaagagatga tcaacttatc gtaatctgtt
     1861 tttatttctt catttgtgga taggtcttta actgttaatc gcttagtaga aggatcgatt
     1921 gctgttactt cgtgtttagt aaagacatcg atgttgtttt ttgttttcaa tatttctggt
     1981 gtacgttcga tcagcgagtc acggtcagtg atcacacctc ctaaataata aggcaaagca
     2041 caacttgcat aagaaatatt ttctccgcgt tcatagataa tgatttcgtg cgcttcattc
     2101 aatcgacgga aacgagtggc aaatgaagga ccgccagcta caccgccaat gacaacaact
     2161 ttcataaaaa catctccttt tctacgttga tcgtactatg ttatggtaaa aaacagcaaa
     2221 taattgtgcc ggaaaattat tgtttatttt gaatagacag aaaatataga gaaataattt
     2281 gtggataaaa cctaaaaatt tttttctatt ttaaggatag ataatacttt gaaggggata
     2341 accctgtata ttttttaaaa gctgaagaaa aatgatggat cgaatgaaat cctaatatat
     2401 ctgcaatttc tgtataggtt aattcatttt ctagcacgag acgttttgct ttttccattt
     2461 ttagttcttt aaaatagcta ataacacttt ttccattcac ttttctaaaa tgttttttta
     2521 agctggctgg actgataaaa aaaatttggg ctaattgttc aagcaaaaaa ttttctgaaa
     2581 gatgttcttc taaatatcgt atgattggat caactaattc atctgaataa agaatatgct
     2641 tttttttagg aatgactttc tcatttgaag gtattgtcaa taaagcaagt tcctgttgat
     2701 aatgccttgg taaggaagac aattgaattt tttgcagaca ataagtaact aataaggaaa
     2761 gcaaatgaat gctcatctgt tggcatagta tgaaaaaaga attgatttcc tgatcatagg
     2821 aaatagctgg cttactatgt tttagataat caattttgaa ctgttcattt ttcagaaaag
     2881 taatgataga tgttatttct tgatctatag aaaaagattg tcccgtaata tgtgctaata
     2941 attgctcatc aaaataaaac tggataatga taaaagtttg tgtttccttt tgagtagaaa
     3001 agatttggac ttcttgctgt ttatcaatga ataaaaggga aggattatct agttctatag
     3061 atctatgtgc aaattcagca tataaattag cgctttcatt tattagtagt cgaaaatagg
     3121 gagcagcaga taaatgaaga tgggtatcta tggaataggt tagtgttttt ttgacaagat
     3181 tggaggattg gttgtttgtt aacaaaagaa ccactttcct ttctcttttt atataaaaag
     3241 ctttctattt ataattaatg actattataa caaaaatgaa aagccaaaac gacaagtaaa
     3301 atattttttt atataaatat ttgtgttact aattccgtta atatacataa gtgaaagcgt
     3361 tttatataag aacttgaaaa gaaagaaggg atagacatga aaaaaagata caaattggtg
     3421 atagctttgc taaacattac cctattattc agcttaagtg catgtggaaa aactaacgaa
     3481 gaagtaacag caaacatcgc agatccaatg ataaaaaaag ccactacatt agaagtatat
     3541 gtcgcaaacg gcaaactgac aaactatgtt gaaaatgctg caaaaatcta taaccgcaaa
     3601 actggagcaa atattgactt aaaaattgtg aatgtagctt cgggaacagc aacagtacaa
     3661 atgatcaccc caaaattggt aacacacgaa gatatgccgg atattatctc catggcagac
     3721 acttcagcag caggtgtgct ggaaaaattt caagatgctt tttatagtgc tgatgaatat
     3781 ggattttatg acaaatatgg cgatcagttt tatgatcaaa aattgaatat tttgcgtcaa
     3841 caaacgagta atgaaacgat tattccttgg gctagtgatt ttaccccagc actttgttat
     3901 tatcaaccaa aaaaatttgc tgaaataggt gtagattttg aagaaatcag ttcttgggaa
     3961 gaatatatcc aggtggcaaa agcattaaaa gaaaaaactg gtagttttgg aattgccttg
     4021 ccagaatctg gggaccaaga attgtttatc aacatgctag cccagcagaa tcaatctttg
     4081 cttgatgaag aaggaaatat ccgtctgaat actaaagaag cgaaacatgc tgcaaagtta
     4141 atcaaagaaa tgatcgactc agatattgta catttctacg gtgcacaaga tgctgagaaa
     4201 gcatttcaag aatctgcaat gtttgttgct ggcggctggt atgctacgaa tatgtctttg
     4261 aattttcctg atgcatctga caaatggcgc atggctccac tgattccttt ttcaaaagaa
     4321 aatccaggaa aaggtgcagt atcaggagga tcaagttttt atgtccctaa agatgccaaa
     4381 aatccacaag tggcacaaca atttcttaca tttatgctga cagatgaaga atgcttagcc
     4441 aacgcactgg agctgggcgt ggctacatct aactcattgg cctatcaaac agaagcagct
     4501 gagaaaaagt ttgactacta aggaggacaa aaatactatg aactattgaa taaaatcaat
     4561 gaaaatacat caaatactgt tttaccagcc acttattcag atgctacgtc ttatttgact
     4621 accgctgcat ataactattg gcaaacaggt gattttgaaa attcatatct aaaagaagca
     4681 gaaaattttg ctcataagta cggcgtaaaa ttaactggtg attaaaaaat attaggagga
     4741 cttaacgatg atgcaatctt cgttaccaag caagacaata aagaacagca agaaaaaagc
     4801 aacagatacg tctcataaaa aaagtgctta tggattggtc acaccttttg ttattttctt
     4861 tattgtgacg attttgattc ccatcattat ctcgtttgct tttagtttta tgaaaattgg
     4921 ctactcattt gaatttgttg gatttgacaa ttatctagct atcttccgag atccattgtt
     4981 tattaaatct tacacgaatg ttttgattat catggcagga tcaattccaa taacgatgct
     5041 attagctatt tactttgctg ttttattgaa ttcagcacag ttaaaaggaa aaggattttt
     5101 tagaactgtc tattatattc caaccattac atcaacggtg gctgtagctt ccgtattcat
     5161 gacttttttc aatccgactg ggttattcaa tggatttttg aatgcgctag gaattaacgg
     5221 tgtacagtgg ttaacaaatc ctttttggat acgaatatca atgatcatca cgatgatttg
     5281 gcttagtgta ggatataaca ctattttatt tttagctggt cttcaaggga tttctaaaga
     5341 gatatacgaa agtgctgaaa tagatggagc atcgaaattt cggcaattct ttttattaac
     5401 gatccccatg ctaaagccaa tcattttaat ggccacagtt ttagccacta tcaatggctt
     5461 gggtaatttc aatatcccaa atatattctt tgggacttcc aatggaccag aaaattcagc
     5521 tttggtcgta ggagtcaatt tatataaaac aagttttgaa atggttgatt ttggaaaagc
     5581 ctctgctatt gcctggacga tggtgtttgt atctgttata ttatcggcta ttcaatttaa
     5641 attcggaggt gataaaaatg actaaacaaa agatacaaag cagaattttt acgtacgtca
     5701 ttattgtgtt tggtgcctta atatttttga tgccatattt atatatgatt gtagcttcaa
     5761 cgcaaagtaa tcaagaaatt ttaagtggcg gaatcaattt caagtttggg gatatgctat
     5821 taaaaaactg gcaagccatc atggcgagat ataattatcc cttgattatt tggaattcga
     5881 ttgttattgc tgtaatcagt acagttttag ctacagccag ttctacaatg gcgggttatg
     5941 cattagcaaa gtatcgtttt atggggaata aactgttgtt caatacagtt atgctatcta
     6001 ggatggtgcc tttttttacc acattgattc ctttatttta cattatgagt cgtttaggat
     6061 tatcgaatac ttatgcaggt gtgatcatcc cttcgattgc cagtacaact tcagtgttta
     6121 tgatgcgaca atatagcagt caatttccta cagcactgat ggaggctgcc agaatcgatg
     6181 gtgccaatga gtgggtgatt tttacgaaaa tcgctgtacc gattttatca cctacgatta
     6241 ttactagtgg tttacttatc tttatgggaa gttggaatca atatctattt ccattagtca
     6301 tgctttcaga taaagataaa tatacggttc ccttaattat caaaaatatg acggtttcta
     6361 gtacaggtga gccaattaat tatggcgcaa ttatgctaat tttagcaact tcagtgatcc
     6421 caatggtctt gatttatgtg tgggcgcagt ctaaatttaa ggagaatgac attggagctg
     6481 caaataagta aaaaaaataa cgaatgttaa ccatctagtt cgttctagga gcaactccac
     6541 attcataaaa attaaaagaa tggcgggata tccatgaatg aacagacgaa ggaatggtca
     6601 agaaaaattt tgaatgtagc ttctgaaaag atagatgcgg aattagacag aatggggaat
     6661 aaaattccat atatttctta caacggaaaa tatacagacg taataaagga cagaggaatc
     6721 gactggtgga ccaatggttt ttggagtggt attttatggc agctctttca caagacaaaa
     6781 cgagaaaagt tcaaagaggc agcaatacaa caagaacaat tattagaatc tgccctgtac
     6841 catttttcag acgttcatca tgatgtaggt tttttattct taccatcggc tattgcacat
     6901 tatcaacagt ctcaaaacaa acatagtcga caactagggt tacatgcagc tacggtactt
     6961 gctggacgct ataatatttc agggaactat ttagtagcat ggaatgacca taaacctggt
     7021 tggatgatta ttgatagtat gatgaattta ccattactgt attgggcttc gagggaaact
     7081 ggtgatccga ggttctctaa aattgctcgg cagcatgcag atacaacagc taagtatcta
     7141 gtgaggaaag atggatcaac cgggcatatc gcagaatttg atgcagaatc agggaaatat
     7201 attcggttac ttggcgggca aggatacaat gagaattctt gttggagcag aggaaatgca
     7261 tgggctttat atggattcgc gttaagttat cgttacacaa aaaatccgta ctatctagct
     7321 atagcagaaa agatagcagt aaattttatt cagaaaatcg aaaaaactgg ttatattcct
     7381 ctcattgatt ttgctgtaaa agattcgaat attgatacca gtgctggagt atgcgctgca
     7441 tgcggtcttc tggaattagc aggatatgtt tcctctgtac gatcaaaaat gtatcatgaa
     7501 gctgctatca atatactcca aaagacagaa aagcactatg caaattggaa tatggatgaa
     7561 gatgggatca ttggaggcgg agcagaagca taccatagag aactgactta taatgtgcca
     7621 ctgatctatt ctgattattt ttttattgaa ggcttacttc gattagaaca gtcggaatta
     7681 gctatttggt agtaaaaaga ggagaaaata caatgaaaca tccagtacca ctattaagga
     7741 ccagacagga ttactttgac ttatttaaaa agataaatca accactccag ccgttttatc
     7801 gagcaagtgg cgcacaaatt gattatatac atcaaggggt aggatatgga aataaaattg
     7861 caggaatgga aggattctct cgggttttat ggggagcggg gcccgcaatt gaccaattag
     7921 atgaacgatg gttgaaatta attctatcag gaataaaagc tggaacagat ccttcccatc
     7981 ccgattattg gggagaaata catgaaagag accagcgtat ggtagaaatg cccgcaatgt
     8041 tattagcgtt atatcatcat gaacaattat tatggaaaaa attagataca ggagaaaaaa
     8101 gccagattat tcattggttc tcgcaaattt ttgaatatga atgtgcagat ggtaattggc
     8161 aattttttaa gataattgtc ggaacaatta tccaaaaatt tggttatcca gttaaagaat
     8221 cagcactgaa agaagcattt gataatatag aaaattgtta tcttcaaaat ggctggtatc
     8281 gagacagttc aagaggtcgc caagattatt ataatccttt tgcatttcat tattatggtt
     8341 tgatttatag cgtactagaa ccagaaaagc ccattagcca gatatataag aaccgagcta
     8401 ttgatttttc tagagactat attcattttt ttgcggaaga tggtgcaaat gtgccttttg
     8461 gtcgaagcat gatttatcgt tttgcagttt caagcttttg gtcagctatg ttgtgggccg
     8521 atcttttgcc ttttaaatta ggtgaaatca aggggttagt caatcggaat ataagatggt
     8581 ggatgcaaaa agaaatattt gatgaaaaag gtatcctgaa tattggttat acctaccctc
     8641 aattgacatt gactgaaccc tataatagta cgttatctcc attatggctg aataagattt
     8701 ttttattgtt ggcgctacct gaagaccatg agtattggac ggctaaagaa atgcctatgc
     8761 ctattcgtga aggaactaaa cttctttcag aagccaattt gctcatacaa catgataatg
     8821 gacatacatt ttttttgaat gcgggacaat tagggccaaa tttccataca ttgaccaatg
     8881 aaaaatattt aaaatttgct tattctagtc aatttggttt ttcgataccg cgagcgaatc
     8941 aattgaaagc agaaatggca atggattcaa tgctagggat tcagcgagcg gacacatata
     9001 tcacgaccag ttttaagaat gagagcatca aaacctatgg acagttcatc gttcgaaata
     9061 atgtacgaga cattgtatgt aagaaagagg tacttgcctc tacatgggaa cctactttac
     9121 aggcaaaaat cagaacttgg cttattcctt ttgaaggctg gcagattcgc gtacacaaag
     9181 tagaattaga tacagaatat gttctatatg agacagggtt tgctattgaa tgttctcctg
     9241 agaaagaagg aataatcata gaagaagaca aggaaaacta tagggtgagt gaagctggct
     9301 tttcaggtat tatctgttta agtgacgata ctattaaacg aaaatccaca gctattatgg
     9361 gtttgcccaa tacaaacttg atgacatggg aaaacacttt tattcctgga ttagagggta
     9421 catttggaaa aggaacccat tggctcggaa caggagtggt tgctcatcaa gatcgggatt
     9481 atagtttaga agtatggaac aatcgtccca aaattgattt tgatgggaca accgggctaa
     9541 ctatccaaaa taaaaacaat aaaaaaagac taaaattatg ctaaaggctg gtggggaaat
     9601 gcttgataaa gtgatgtttg aagagataat acatccagaa aaatggataa atgaatgtta
     9661 taaagaatta atggaaaaag aatggaataa tgagatcgag cgttgtcgca gacacacgga
     9721 gaggttaatc aaacgtatca gtaacagtca gtatcaattc ccaagcgagt gtcctataaa
     9781 aggacgttat ccattaagag acaatattgg ttggacagaa ggattttgga caggaattaa
     9841 ttggttgtta tttgagaaga cgggtgatcc tttatttcaa caaacagctg aaaaagcaga
     9901 tatagatttt atccacagga ttgactgtca aattatcact aatcatcacg atcttggttt
     9961 tttgtattct ttatcaaccg tagcagatta taaaataacg ggaaatcgaa aaatgaagga
    10021 agcttcaatt gatgctgcag aaacattact tcagcgtttt tgggagaagg caggagttat
    10081 acaagcttgg ggagatccta gtgatccttc acaacaaggt agaatgatca tggattgttg
    10141 catgaatctt ccattattgt attgggcgag tgaagaaact ggaaatcaaa aatataaaaa
    10201 agctgctcag gctcatattc aaaatgcagc agattattta gtaagagaag atggttcaac
    10261 ttatcataca ttttatatgg atgtcaaaga tggaaaacca agatatggaa gtacgcatca
    10321 aggttatagt gataattcct gttgggctag aggccaagca tgggggattt acggttttgc
    10381 attaagttat cgttatttga aagaacaaaa atattttgat ttaagcaaaa tattagccaa
    10441 ttattttatg aatcggttgc cagaagatac catttgttat tgggatttga tctttgatga
    10501 ttctagcaga gaagaaaaag atacatctag tatggtgatc atggtttgtg gattattaga
    10561 attaatagaa tcaggtctat tagacaaaac agaaaagaac ttataccagt ctgctgtttg
    10621 gaaaattatg cgacaattga aagaaagata tgctacaacg gaagaagaag atggcttttt
    10681 aacacagtct gtttataata agcccaaaaa taatggggta aatacacctt gtatttgggg
    10741 tgattactat tatttagaag ctttagtgag aatgactagt aattggtctt cttattggtg
    10801 aaaaaggtaa atatggaatt tttgtttgat aaaataaaaa aagaaaaacc aaaacagcat
    10861 gaatggtttc tgttttggtt ttttcgttaa ttttcatatt cttctaattc caagcttagt
    10921 tcttcccatt ccgtcaattt tgtttcttga tcttgtctag cagcttctaa atcttggttc
    10981 agctcattga gttttacgtg atcttccagg ttttctggcg cgaccatttc ttgttccaac
    11041 tgatcgatcc attcatcgat ccgcgccatt tcttcttcaa cctgagtaat ttttcgttga
    11101 aggctacgga taagcttttg ctgttctttg ctttggtaat aatcagattt gttcgtggga
    11161 gcaggagcag attctggctc atcttgtgcc aacaattcgg cgatttcttc ttcttcctgc
    11221 tttttctcta aataataatc atagtctcct agatagactt tgctgccatt ttcagagagt
    11281 tcgacgactt ttgtcgcgat ccgattgatg aaatatcggt catgggaaac aaaaagcagt
    11341 gtgccgtcat aatcgatcaa tgcattttct aatacttctt tgttgtcaat atctaaatgg
    11401 tttgttggtt catccaaaat caaaaaattt tctttgttca tcgctaactt ggctaaagca
    11461 acccgtgctt tttcaccgcc acttagcaga gggattggtt tttctacatc ttcgccagaa
    11521 aataagaaag cacctaaagc acttcggatc tctttttctg gagtggtagg atgctcatcc
    11581 cacaattctg ctaggatcgt cttgtttgta tgcagatcag cttgaccttg atcgtaatag
    11641 ccgatggtga catttgtccc tagcgtttct tttccacgga taaaagggat ctggtgaatg
    11701 attgatttca gcaacgtcga tttcccgata ccattcggac ctactagagc aatcgcttct
    11761 tgacgacgga tatctagatt gattggttca gataaggtga cattatcata tccgatagcg
    11821 gcatcttcga tttgcaagac tacatttcca gaaggctttt ctatactgaa tagaaagttt
    11881 gcttgttttt catccccttg aggacgatcc agccggtcca ttttttctaa tgtctttctg
    11941 cggctttgcg ctcgttttgt ggtagaggcg cgaacaaggt tccgagcaac gaagtcttct
    12001 aatttatgga tttctgtttg ctgcttttca taagccttcc attcacttgc taactgttct
    12061 gctttcaaat ctagatattt cgaatagtta cctttgtaat ggcgcatttt tcttctgctt
    12121 aattcataga cttcattgac tactttatct aaaaaataac ggtcatggga aacaatcaat
    12181 aatgcaccag tatagctttg cagataattc tcaagccagg aaagtgtctc gatatctaaa
    12241 tggttcgttg gttcatctag aatcaaaatg tcagggtgtt gcaaaagcat gcgagctaaa
    12301 gctaaacgtg tgcgctgtcc gcctgataaa gtatcgattt tctgatcata aaatgaagaa
    12361 tcgaatttaa acccatgcaa tacggaacga atttcatttt cataaccata gccgtttcga
    12421 tctgaaaaat cgtgttgcag ccggtcgtat tcttttaaat aagaactata agcaggtgtg
    12481 tctggcgtac cttcgctaat gaaaatctct agctcgcgca tccgctcttc catttgtcta
    12541 acttgttcaa aagctttcag catctcgttc caaactgttt cattggaatc aagtcctgtg
    12601 tcctgagcga ggtatccgag agtcgctgtt ttatttttag cgatctttcc ttcatcaggt
    12661 gcttcaattc cagcaatgat ctttaataaa gtcgattttc cagcgccatt tctgccaact
    12721 aaagcgacac gagcgcctgt actgatttct aaatgtatgt tttcaaataa gacttctgca
    12781 ccaaaatggc gagcaatctg attggcttgt aataatatca tggaatcctc ttttctactt
    12841 tgtgaattct cctcaaataa aaaactattt ttcaattagt agtctaccat aaattccatt
    12901 atactgcgag atttgcagaa atgataaata aatgaataaa gaataaaatt tcacaatatc
    12961 tgagcaatgg aattgatttt ttcctataaa tactgctatg atggagaaat caaagatgta
    13021 attagacaat acgtggaggt catttcgtga aagatcatat tattccaaag gcgacagcta
    13081 aaagactgcc tttgtattat cgctatttaa ggattttaaa taatgctgga aagaaaaaag
    13141 tgtcttcaac tgaattaagt gaagccgttc aagtagatag tgcaacgatc cgtcgagatt
    13201 tttcttattt tggcgaatta ggaaaacgtg ggtatggtta tgatgtagaa gatcttatgc
    13261 acttttttgc aaagacatta aacgacgatc aattgacaaa tgttgcgctg atcggtgtag
    13321 ggaacttggg aagtgcttta ctaaaataca aattccatca aagtaatagc atacgtatca
    13381 gttgtgcttt tgatgtgaat gaggaaatcg ttgggcgcat cgtagacggt atccccgttt
    13441 atccaatgga agatatgtca gaacaaatca agatccaaca aatcgaagta gcaattttaa
    13501 cgatacccgc tgaaagagca caagaagtag tcaatcagtt aacggaagca ggaatcaaag
    13561 gaatcttgaa ctttaccgct gctcgattga atgctccgtc agatgtattg atccaaaatg
    13621 ttgatttgac gaatgaattg caaaccttga tctatttctt gcattctgac gcaaatgcgc
    13681 attccgaaaa tacagcagaa taaaaataaa aagcgattga acaaatgaag gcaaaacttt
    13741 cacttgttca atcgcttttt tctgtttgga caacgattat tttgttcgga agatttcttc
    13801 ataagaaagg gaatcatctt ctgctgtcag ttcatctagt agataacgga tttttttaaa
    13861 gtcgatgaac cgtgcttgcc gaaagacttc ttttccttga tgaaaaatca ggacaactgg
    13921 cgcagtcagc acttcaaatt tactagctac ttctggtgtt tcaaatgcat ccaaatgaag
    13981 tgccggaata tcataatgtg tgagaagttc ctctagtcgt ggacgaacag cgtgacaaac
    14041 actgcaatta ggcatcgaaa gataaatgac ggcaacggat gactgttgca gtatgtcttg
    14101 aacttcagtc aagttagtgg tttgtttcat ttttattctc ccttttatga tagaagtgat
    14161 atgtatgaga ccttaattta atgggaataa cagaaaaagt caattgaagt gctttggtaa
    14221 aaaataagag ttgtgtaaaa atttacagag caacttgttt tttttgaata aaagcgtata
    14281 tttgcaaagc gaatgaacta gaaataaaaa ggaggaaact catgttttct tttattccaa
    14341 attcggtttt gcagatgagt acgattttct tatcgatcgt tattgaagca ttacctttcg
    14401 tattattagg ctgtcttatc tcaggcgcct tacaagtatt tttgacccca gaacgtgtga
    14461 agagatggct tcctgaaaat cgtatcttct ctatttttac tggttcgatc ttaggatttt
    14521 tctttccttc atgtgaatgc ggcatcgtac cgatcgttca tcaatttgtt aaaaaaggcg
    14581 taccagttca cacagcgttt gcttttatgc tgactgctcc gatcatcaat ccaatcgtga
    14641 ttttttccac ttttatcgca tttggcaatt cttggcagat ggcaagctgg cgggtgatag
    14701 gcagcttttt tgttgccctt gtgattggtg tctggcttgc ctattttcaa aaagacgctg
    14761 tattgaaaga aaaaatcacg tctaaagtag cagaaaatca ccatcatcat gtccatgaag
    14821 aagaacaaag tgagaagaat gaaccaaaaa atcagctgat ccatcaaact gggcatgtgt
    14881 tgacacattc aatcgacgaa ttttttgata caggtcgtta tttgatcatt ggcggattaa
    14941 tcgcagctgc gatgcagact tatttaccaa ctagaattat gctaacgctc ggctcaacaa
    15001 agattttagc cattatcatc atgctgttat tggcctttac gatgtctctt tgctcagaag
    15061 cagatgcgtt tataggatct tctttgttaa gtctgttcgg cacagcacct gtagctgcct
    15121 ttttggtctt tggcccaatg gtcgatatca aaaatctact gatgatgaaa cgatatttta
    15181 caggacgctt tattttatcg ctgatcggac tgattgccct tagcgttatt ggattcacat
    15241 tatttattta ggagggaaaa tatgctgcgg tttttgattt tatctgggta tttcgaattg
    15301 atgatgtact tgcaagtttc tggcaaactc gatcaatata tcaatgtcca ttatcgctac
    15361 ttagctattc tttcaatgat tttatctgct cttttggctt tagttcagct gtatttgtgg
    15421 gtcaaaaacg gaaaagcaga agaaaaggca cacgagcacg atcatgacca tgggttgtca
    15481 aaaccttatc aacgtggaat cgcttatgta ctgctagctt tgccagtaat cgtggggacg
    15541 ttgtttccaa cagttagtct cgacactacg atcgtagaag ccaaaggatt taatttccca
    15601 gtaagtaaag aatcagtagg ggatccggag atgcagacac aatacttaaa gccggatacc
    15661 agtatttatt tcaacaaatc agactactta gaccaaatga atgagttgaa agaaaagtat
    15721 ggggataagc aaactatcaa gatcacagat gaaaactatt tagaagttat ggagctaatt
    15781 tataattacc ctagcgaatt cattggcaaa aaaatcagct atgaaggatt tgtttaccaa
    15841 acaccgaacg atagcaatac agatatcttc ttgttccgat tcggcattat ccattgtgtg
    15901 gcagattcag gagtctttgg tttgttgacg catatgccgg aaggagtaac ggttaaaaat
    15961 gatgaatggt ataaaataga aggaaccatc caatcagact attatcaacc attcaagcgt
    16021 gaaatcccat ctgtagttgt tacaaacgct gagaaagtct ctgctccgaa aaatcagtat
    16081 gtgtatcgtt ctttttaaaa gaacaaaata aataaacata gctcagacag ctgacacgca
    16141 aggacgtcgg ttgtctggct ttttttgcat gatgtattca tttgtttgat atttatttta
    16201 gaagcagcat cctgaaagta tttgatatcg gtttcaaagg tgttggaaaa gattgtgaag
    16261 agaattacaa tttattccta acatgtatgt tgaaaagttg tatgaaatga ttttgatagt
    16321 aaaatatcga gtggaggtac tttttatggt aacgcgtata tttattttgg atgatagttt
    16381 ggtttttgaa aaaatgctag tagaaatttt ggaagaatcc agaattttat taagtccttg
    16441 gaaatttgag atcgttcagg gattgaacgt tatacaattt gttgaattca ttaaaaataa
    16501 tgaaatctat tcctcagata tttttttcct agacatcgat ttgaacgcct attatagcgg
    16561 tatcgaacta ggcgaaatgc ttagagaaaa gaatgaaaag tgtaaaattg tttatctaac
    16621 gtctcatccg aataaagcaa taactgttat taatcgaaag attacgccta gtggttattt
    16681 gataaaagaa ttcacttatg aaaaaaataa aaaaagcatc caaagttact tattgaaaga
    16741 aaaagaaaac tatcctgttc aacatgctac gaaaaaaagg tggacaactg tccgttatgg
    16801 taatagcgat cactatatcc attacgatga aatcctttat ctaatgagca tgccaggtta
    16861 taaaaataaa ataggcctag tattgaaaga tgaagagatt ctcgtaaacg gcacaattaa
    16921 aaaatataaa aaatcactcg aatatgagta tttatgtaaa gatttaaaag cttatatcat
    16981 taatactgaa aacattacat ctattagcag agtaaacgaa atagtaacat ttgcaaatgg
    17041 agaacaacta gagatgggaa agagaagtat tgataaacta aagaatttta tgcaagaaaa
    17101 gatagaaaat gaatcatttt aaagaaaaca aagactcata tcttacctgt tagaagagtg
    17161 ttttcctgta gaagagaaca acccaagtag cagcctagtc gtttctatcc ttttttgtta
    17221 tgcactcttt ttgacattta ctccaccaat aacgaagggt acaataaaaa gtaataacaa
    17281 acaaaaggag tacagaaatg attgaattca tcaatgtaag taaaagttac gggaaaaaac
    17341 aagcattaaa agacttgtct ctctcgataa gacaagggga aatttttgga tttttaggac
    17401 ataatggtgc cggaaaatca actacgatta aaagtttagt tagtattatt gaaccatcat
    17461 cgggaacgat tttagtagat ggaatgaaat tgacggaaaa tcgattgagt atcaaacaaa
    17521 aaatcggtta tgtgcctgat tccccagata tttttttaca attgacggct ggagaatatt
    17581 gggacttgat ttcagctgcc tatgaattag acacacaaaa aaaagaaaag cgtttagcag
    17641 aattgacagc gctttttgat atgtatagtc atcaaaatga aacaatcgca agtttttcac
    17701 atggaatgcg tcaaaaaacg attttgatcg gcacgttgct gccagatcca gatatttggg
    17761 tattggatga acctttgcaa ggacttgatc ctcaagcagc atttgatttg aaagaaatga
    17821 tgaaggctca tgccgcaaaa ggaaaaacag tcattttttc tacacatgta ttggataccg
    17881 cacaacagtt atgcgataaa ctggctattt tgaagaaagg tgaattgatt tatcaggggg
    17941 cagttagtga attattgaat ggctcacctg atgaaacgct agaaaagatt tatttgaaaa
    18001 tggctggaag gcaagcgaca ggagatggac cgtatgtata agcgacaatt attagaatta
    18061 attcgagtta atcttttata tgttaatcca cagctcacga ataaagcaag agagaaagga
    18121 aaaaagggaa agcgattaac tatctatctt ttgtctcaaa atcttttttc agggctgatt
    18181 tttttactga tttacggatt tgctatgttt gctatgaact ttgttaaatt gccaggtttc
    18241 tttacttatt acgtggcact ttttggtatg ttaggtttaa ctcaaagtat atcagtcatt
    18301 tataatatct tttttgaagg aaatgacctg caagtatttt tgcctctgcc ttttggacaa
    18361 gaacaggttt tttcagcaaa gattttggta gttgctttga ccatcattcc ttttgttttt
    18421 ccgcttctag tcatgtttat tttaaccgga tggcgagctg atctagggat tttgcttact
    18481 atcattatct caatcctttt gttttctcta tttttgatta ttcttttttg tctggctagt
    18541 ttgattgttt ttggtttggc tcgaacagca gtgtttaaaa aacatagaaa aacagtttct
    18601 agtatcttgc ttggcagctc gatgctgatc gcatttgctg gaatcatgtg gatgaatcat
    18661 caaacgggga ctattgaaaa tgagttaaca gatcggcatc cgatttcgat attattgcca
    18721 ttctatgatg ctgccagtca gccactttct caacaaggtt tattgggttg gggaatacta
    18781 gctatcacgg ctctgggatt tttccttgct gtaaaacagc tgatagtacc aaagcttaca
    18841 gagcaactga ctgattcaaa cagtgagttc aaaataaaaa gaacccataa aaagaaccaa
    18901 aatgtgcatc agcttttatt tagttacaat gctcaattag taaaagaacc taatttgatt
    18961 atgcaagttc tttcttcttc cttgttaact ccaatcattt ttattcttgc ttttgcccta
    19021 ggaggcgaaa taaaattaac tgatttagat aataagttaa tcggtgttgt tttcctggta
    19081 gggatcgcat tggctttctt aacagttaat cagacttctt ttatcagcaa tcttatttct
    19141 ttggatcaag aaaattttct gtttatccgt tctttgccaa tctctatgaa ccaatattta
    19201 aaagaaaagt tcagattcgg atggatattg cagagttttt taactggtgg gatcgcatta
    19261 ttaagcggac tgtcttttca gctgcctttg ttttttatcc ctagcttgct atttggttct
    19321 ttattcggct gctacttatt gtcactacgt tatttcgcta gagattatcg gttgctgctg
    19381 ctgaactgga ccaatattaa ccaattattt aacagaggtt caggaagttt gggtttagtc
    19441 gcaactatga tgggttcatt gatcatcagt attattctta tcgtcttata cggaatgttg
    19501 gctttgtttt atccattttg gttagtgaat attcctgtga tcggtttagt tctaatactt
    19561 tccgctctat ggatcgttta ttatcaacga acgttttgga aaaaatttga ataaagaaga
    19621 ggggccgtga caaaaatcat gtcgcagccc cttttttaca gatagagggt gttcaaaagt
    19681 cagtttctca gtattaagtc aattttatgt aaaaatgtga gaagctattt ttacaaaact
    19741 ttttttaata ctcataatta cttcttattg ctcctgcggt tacttgtcgc aatgtttgtg
    19801 agatattttg tcatcgctca aggctgaacg tctctttcac aaccttttct ttgttacact
    19861 tcgtttattt aaaaagccgt ttttttcgtt tcatcatgat tgcgtcacgc tttactttga
    19921 aattacggat gttatggtta aagacttctg ataatacaag acctaaagcg attgctccag
    19981 caatcataat tgcttggacc gcataatgag ccgcttctcg ataggattca gtaacgagat
    20041 ttcgaaccgc ttgataagct aaaccaccag ggactagagg aaccatcccg ggaatattga
    20101 aaatcgttac gggcattttc aaacgtttag agaaaagatc gctgatgaat gctactccta
    20161 aagaaccaag caatgaacca aaagcagcag atccgcctat ttgaacacag atccagtaga
    20221 tcatccagcc aaaagcacca gaaagaccac aacaaatcaa tgaacgccta ggtacatttg
    20281 taataacggc aaatgccgca gtcgctaaaa aactaaaaga aaactgaata aatatcgtcc
    20341 ccatacttgt gttcctttcc taataaaaaa gctggaaaat aaaagcaatc gcaaaaccga
    20401 tcatcgtagc agtcatcatc gcttctgttc cgcgagaaac tcctgagaca taatgtccag
    20461 ctagcaaatc acggatagcg ttcgtaattt gaactccagg aactaaaggc atcacacatc
    20521 cgataatgat tagatcctga ttgcttccta agccaaaacg tacgctgtag atagcggcta
    20581 tgccaatcaa taaagaagat aaaaattccg ataaaaattt gattctaaaa aatttcaaac
    20641 tatatagata agctgcgtat cccaatcctc caatgactaa agtcacaggt aaatcggtca
    20701 tctttccgcc aaataacacc ataattgttc cactgatcac tgccgcgcta acgatttgca
    20761 accagacagg aaagaaagaa cggtctcggt cgattgcttg cagttcgcag taaagttctt
    20821 ctaatgttag ctctgaagca acatatttac gtgaaagatc atttactttt actacttttt
    20881 ctaaattaat cgaacggttg gtaatttgtt ccattcggat ggtcgaggta cgatcaagac
    20941 caataaagag accggtttga gtgacatagc tgaccaaacg gaaatttcca gaagctaaag
    21001 caattcgact catcgtatct tctacccgat acatctccgc attgctttcc atcatgattt
    21061 tcccagcgag taaacaagtg tccagcaaca gatctaattc ttttcccgtc atagcatctt
    21121 ctccaataat tgattgatta gttttatttt actacaaaac ataccagaag cgtaaagaat
    21181 aaaaaaactt gaggaaggaa taaaagaggc gtatactgtt tttgtattgc gggtgtagtt
    21241 tagtggtaaa atcccagctt cccaagctga tgtcgcgggt tcgattcccg tcacccgctt
    21301 aaaataggtt gtgaaaaagc tgctctgcaa caagtaataa gaacagccaa gcaaaaacaa
    21361 cttcttatgt ttttaacttg gatggactta ttaccgcaga tgcaagcttt tgcgcaccgt
    21421 ttaccaagcg gttgtgaaat cagtgtattg tcttgagtat gaagaaaatt tttgaataat
    21481 aataaatacc ttacagatag agtggtgact gattagagac gaggaatccg tctctttttt
    21541 gtatttttaa gccatcttaa aacaggtttt attttttgct gtttctattt ctttctagta
    21601 tttatttata ggggaacata tgttaagatt tagggagctg ttagtaaagg agtaaagaaa
    21661 tgagcaaaaa aacaaccaag gcgatcgtgg ggatcgtcgc tgctgtgatt gcaggggcat
    21721 tcggtgtttc caccacacaa aaagattcag atatctttca gcagattaca actatttttg
    21781 attccacacc acaagcttct caagtagcgg atgtgccaga atatgatgga aaacatcaag
    21841 aaatagaaat caatgggaat cagccggaat ttacaaaaga ggatcttagc ctttccaaag
    21901 gaacatggga aagctattca aatattgata aattgaacag agtaggacaa gccaatgcta
    21961 tgcttggaaa agatttgttc cctactgaaa agagagagcc tttgtatatt gacccgacag
    22021 gttggaaaca aaagaaatta agtgacgggc aatggttata taatcgcagc catttaattg
    22081 gtttccagct gactggtcaa aataacaaca ttaaaaactt gatgacaggg acacgttcgt
    22141 tgaatgctcc atacatgctt gctcacgaaa atgatattgc ggcatatatc aaagaaacaa
    22201 atcatcatgt acgctaccgt gtcactcctc attttgaggg gaatgaactg gtagccaggg
    22261 gagtgcaatt ggaagcagaa agcattgaag acaaaaaaat tgaattcaat gtctttatct
    22321 acaatgttca agatggctac acgatcaatt atgagacagg acaagcaaca aaaacaaaaa
    22381 attagtagca gctattcgaa ttttttatga atattatgaa aaaattgtgt aaaaacatac
    22441 attcaaagaa atatagcgta tactttatga aaagagtact tttgataaag ctacagaaaa
    22501 aaggaaaaaa acatacaaat agtgtttctt aatttattcg gaagtttgga atatttgttt
    22561 gtagttttcc ctttcttcga gtaaaataag gttgtagaag gtaagctgga attaccttgc
    22621 gggaaagagg tgtagaatca tgggttttac agatgaaacc gtacgttttg gttttgacga
    22681 tagtcgcaaa aaagaagtga gcgaaacatt agcgattgtt tatcgggctt tggaagaaaa
    22741 aggctacaat ccaatcaatc agattgtcgg ctacttgctt tctggagacc cggcctacat
    22801 tcctcgttat cgtgatgctc gaaatttgat tcgccgtcac gaacgcgatg agatcatgga
    22861 agtaattgtc aaggactacc tctcaaatca tggagtgaat ttatgagagt aatgggcttg
    22921 gatgtcggtt ctaagacagt aggtgttgct atcagtgacc cctttggctg gacagctcaa
    22981 ggagtagaga tcattcggat caatgaagca gaagaagagt ttggctttga tcggttgaag
    23041 gaattagtag cacaatatga agtagaccgg tttgtagttg gattacctaa aaatatgaac
    23101 aattccatcg gaccaagggc agaagcttcc atgtcatacg gagaaaagat caaagaacta
    23161 ttctccttgc cagttgatta tcaagatgaa cgattaacca ctgttcaggc agaacgtatg
    23221 ctagtagagc aggcaaatac ttcaagagcc aaacgaaaaa aagtcatcga taaattagca
    23281 gctgtgatga tcttacaaaa ttatttagac ggctcaggta agcaattatt ttaataataa
    23341 aagaaaagag gtaatcttat gacagaacat aaccattccc acgaccatga aggacacgaa
    23401 cacatcacat tggtggatga ccaaggaaat gaaacattat atgaaatcct actaacagtt
    23461 gacggacaag aagaatttgg acgtaactat gttcttttat atcctgctgg tgtttcagaa
    23521 gatgaagatg tagaattaca agcttatgca tacatcgaaa acgaagatgg aacagaaggc
    23581 gagttagaac aaatcgaaac agacgcagaa tgggacatga ttgaagaagt attcaataca
    23641 ttcatggcgg aagaagaaga atagactata aagctaggag aaaccttgat atgatagggt
    23701 ttctcctttt tttatttttt actgtatgcc atattgtatg ccatctagtc aatatttaag
    23761 tgttgtacta atttttcaac agtcttttct ttcgtttctt ttgccaagtg accgtaacaa
    23821 tcgatcgtct gactaatttt tgtatgccgt aatctagttt gaacttctac catagtagct
    23881 ccagcgtcca agagcattga agcatgagtg tgtcttgcta catgcacacc gagaaatgga
    23941 accatagctt tttcacaaat agtaatcaat cttgcataaa tagcgtggtg tgtgattagt
    24001 tctttataga taccacaaaa aatcatagtc ggatcagtta caccaagtgt cagcatatat
    24061 ttccgctgat taatctgcca tttttttaat atagaaattg ttctttcatc tagtggaaga
    24121 accccagcac tacaatcagt tttaggatca ctgattttat agccattttt ggattggctt
    24181 agtgttttat tgatggtgac cgtattttct tgaaaatcaa tgtctgacca attcaatgca
    24241 agggcttcac tgatcctaac cccgctataa aagagaaagc gtagtaacgt tttatcaaag
    24301 tcgtttcgat aagtttcagg tttgctgttt aggtaatcaa acaaggtgat cagttgttct
    24361 ttactgtaaa ctttgacctt ttctttatgc ttagtggtgg ttcttttagg cattaatacg
    24421 ttgtctagtg gattagtctc aataatccca agattgatag cgtagctaaa aatacgctta
    24481 gaagttgaat gaagtacctt gtattggtca gtagtttcag cccagctatt tacaatttgt
    24541 tgggcttttt ttaccgtgac ttcattcaca cgaagatttc catattttgg aagaatccac
    24601 tttctaaact tgatttcagt tttcatgaag gtggcttctc ggacagtggt tttatatgtt
    24661 tctagccaca agtcataaac ttctttaaac gtttcgttgt tcgctttttt aataccgttt
    24721 ttatcgtagt ccacttgcaa gcgtgacaag gcaagctggg cttctttttt tgttttgtaa
    24781 cctcgtctac gaaccttatc aggtttgcca gtcattttgt tcattccaag ataggcttca
    24841 tagagccaaa atttaccttt tttagtttca tattgcttga atgttgccat aatagttttc
    24901 cctccatagt gtagcaagcc gtgggggcgg ttggaggagg cagtttatta ttattttgaa
    24961 tagtgtttat ttagctcagt aacaagagct gtgaactctt ttagaagatc attttcataa
    25021 aattcttgat actctttttt ctcatctgta tttttttctg aatcattaat taatgagtca
    25081 tatcgtaaaa gcgtatttag aagagctgcg agataagcaa ttggggtact cccgtcagga
    25141 aattcaattc gagatcctgt tttaagatat tttattgcgt ttgttaaata aatcttctgt
    25201 gagacagtca ggttatcttc ttcgatgtta ttgatagcat tagaaagatt agaatcaatt
    25261 atagagttat ttttttcaat agtttttttc aattgctttt caagcacatt tcgcttaatt
    25321 tcgggcatca tatgcatatc tcttaatgta taagatccgt ttaatagata ggtagtggat
    25381 acatctaata cctttgaaag ttgtttaagc ctggtgttat tgggaagatt atagccattt
    25441 tcccaattac taacggcacc tttactggcc ggtggggata atttacctcc aagttgttcc
    25501 attgagagtc ccttttcaat tctagccagt ctaattcttt gtcctgtctc cactgcttcg
    25561 gggtattttt ttctagccac attttcacca ccattcatat attttctcta ctatatcacg
    25621 atttaaatat gtgtgaaaca taaaagttca aaaaagtatg ttaaaattct tgcaaatgaa
    25681 aaggtatgat ggtatattga gtttataaga ggtatagaaa tgtattcaag agcctcttgc
    25741 atttttttaa aatctttgta tagaaatgta tgctaacgag gggggataaa tatggaatta
    25801 aaaattgaca aactcacgct tgatgatcca gcttttaaaa ttattgacga tcgagttgtt
    25861 caacaagtag agcaaactca aggaacgtta ctttcattat tagaaaaaaa gtaccagttt
    25921 ccaaaatata tgaacaaggc acaagctgct aagtatatga acgtttcata caatactatg
    25981 atgcagaaat atgttcctaa cggtttaaag ttgattatag ttgatggagt cgtaagaatt
    26041 tcacaagatg aatgtgatcg ctttatggaa gaataccaaa aataaacgca agccgtgggg
    26101 gcaaagggat taataggagg aaataataat ggaatcgaca caaaataaag caatcgaaaa
    26161 agtattatca acaattctta cagaagacac agcggcagaa ttagcaaact tggaaggcaa
    26221 agcgctagaa gaaacgtttg aatgtttgta cgaacaaatg gactatcaaa aattgctacc
    26281 acaagaacca acggtaagcg gagtattgcg tggcttgaac gatttagtac aagcagagtt
    26341 taaagaacga ctttctattg aagagtatca agaaattttg tatcagcaag ttgagttgtt
    26401 agcgagcttg ctagggcttg aactggagga cgttgaatga aaactgaaat ttggaacgga
    26461 cacattataa gatttgtcga tattaatgat gaatggtggg cagtggcgaa agatgttgcg
    26521 gaagcgttag gtcttaaaca ggttactaga gccattcact ctttgcctaa agatggggtt
    26581 actactagta aggtcatcga ttcattgggc agaacacaag atgtaaacat catcaacgaa
    26641 aaaaaatatt taccgcatgg cattcaaaag ccgtaaaaaa gaagccgagg catttcaaga
    26701 ctggattttc gacatcatca aagaactacg ccagtccaca ggacttgaag gctttcaagt
    26761 attccgcatg ctagacaaag aacaccaaaa agaagcaatg actaaattaa gccacgctat
    26821 tactgaacca aaaccagtag actacattaa agcgaatgtg atagccaata aagctgtatc
    26881 aactatttat ggtcattcca aaatggtaaa aaagaaagat atgactcctg aaatgttggt
    26941 tgatcgtgaa cctattttag atgagacagt agaattaatg actgttaaag aaaaatatgg
    27001 gttgcagttt tcagtgagtg agaaaattta taatcgttct gctgaattgc agacaactta
    27061 ggagcattaa catgatcgag aacaaagaaa aagccttatc cataacagtc ttggcggaca
    27121 ggataaaggc aacttaattg ggataaaacc cgatattctt tgttccgatt ataccatatt
    27181 aaaaaatcgg agggaaccat tatgaaacga aacttaatta taggaagcat tttaatcggc
    27241 ggaattttcg gcttattacc attaattgca aaaatagcta tctttgcagg attagcgtta
    27301 tatctcttca ctgcttatga cgagtacgac tatcaattaa gaactggagg gcataagtag
    27361 atgtacaaaa caaaactatt aaaccaactc gatagccttg aattagagga aattaatcaa
    27421 gggatcgctg aactagaaaa taatatcggg aaaacctact ttggaaattc attcaatgaa
    27481 aaactaacag ttttgtatgt actcaaaaaa catgcagaac acaaaataat ttgtcgagaa
    27541 atcaacgagc taaaaaatca gattttaacc gcatggttaa acattactga tatgcaagaa
    27601 gcaagggtga aaacatttaa tacatgggta aagtatcaga atcaattaaa aggtgctgaa
    27661 tttgttcggg atgggttgaa atacgaactt gagcagttga agctcatgga ggtgtctgaa
    27721 tgatttatac cagtattttg aaaaaggagg agaggtttat tggcaaataa ttatcaagca
    27781 gcaacggaat tacaaaagtc gggatggtca atttatccct tatctcctgg aactaaaatt
    27841 ccaataaaag gctctagtgg ttggaatgat gcaactaacg attctaatca aattaatgaa
    27901 tggtggacgg aagatgcaac tagaaatatt gggttaatgc ttgaagatca tcaaatggtg
    27961 gtagttgacc tagatcaaca ttctgaaaca cgaaacggcg ttgagaatta taaaaaactt
    28021 gcttcaatgt atgatccatt tccttctact tatacggaaa tcacaccagg taaaggaatc
    28081 catttcttct ttaaaattcc tgatggtgta attatccaac aagaaacagg tgcatttgct
    28141 gatatcttcg ggcgtgatga taaaggtaaa agtttaagcg ggattgatat tatcactaaa
    28201 ggagttccaa tagcgccaac tatgattatt tcaagaagtg ttgggagagc atatgaacct
    28261 attgaaaacg tatctctaaa taatattgca ccagctcccg attggctagt gaacctactg
    28321 ctaaaaaaac cgcaagaaat aaagactcaa taccgacccg tagcaaaaac agggacagca
    28381 aaaaaattag atatgattgt tcaaggcgct ggcgaaggta gtagaaacga tcatttaact
    28441 aagttatgcg gttggttact atggcacggt gtagataatc aaactttagc agaattgatt
    28501 tatacagcaa atgcgtacaa tgaaccaccg ctaaaagata aagaagtgaa tcaaattatt
    28561 cgatcgatga ttaaaaaaga tttgaggggg aaagctcatg gctcataagc ataaattaga
    28621 tagtatttta gactttcccg aagccagcga gcgtgaagac aatatcattg aattgaaaac
    28681 ctggatgtca cgattaagat gcaataaaga cgatcagatt aaaagtaaca gtgttgtgaa
    28741 tgcagaattg attttaacca atgatagcaa tttagctgga acaattgctt ataacgaatt
    28801 tagcggatac attcacctat taaaagattc tccttggatc aatcgtaccg ctggagaatg
    28861 ggaagacagt tttgaggatg ccttaacggc atatattgaa gaaaactaca atgtagtttt
    28921 tgatgacaac aaaatacaca aagcagtagt aaatgtggct agaaagaatg ttttcaaccc
    28981 agtaaaagaa cgtatcgaaa aagttaaatg ggatcaacag cctagactgg aaacactgtt
    29041 tattgacctt ttaggggtag acgacaacct ttacacacga gaagtaacaa aacgttggat
    29101 agtcggatca gtcgcacgta tctataaacc aggaataaag tttgagatcg ttccagtttt
    29161 ggatggaccg caagggattg gtaagagtac cgttccagca ttactttaca cggatgattt
    29221 tttcaccgat tcattagatt cgctaggtga aaagaaagat gattatatgc agcttcaagg
    29281 caatgtaatt attgaacttg gagaattatc ttcaatgaac aaaactaaaa ttgaacagat
    29341 aaaaaacttc atcagtgcca agatcgataa aattagacct ccttatggtc ggaatgtcat
    29401 agcttgggca aggcaatgtg tatttattgg aacgtcgaat gatgggcagt atttgaaaga
    29461 tgatacagga aaccgccgtt tttatccttt gccttgtaag aataagccaa agatgaatcc
    29521 gtttaaaaca aaggatgaat attttcttca agtgttagct gaagcaaagg tgctttttga
    29581 taaaggacaa cgaatctatt ttagtcccga tgaagataaa gaagtcttag aaattgcaaa
    29641 agactatcaa gaggatgcca agatggagaa tccaattaaa gaagcaatca ctaaatattt
    29701 ggaaatggaa atcccgtata aatgggaaga agctccagcg tgggcgagac gttcttatta
    29761 tcagaactat cctgacagta aatgtaatga gaaaaattta cagcatttct ataatggagc
    29821 tactatgcaa caagagtttt atttagttga tagcgtactc accgctgata ttttggaagc
    29881 tgtttttgat aaacaagcaa aggatttatt gaatggtcga tcagatgcag aaactaaaaa
    29941 gattgccttg attattagca gtattcctgg ttgggaacgg aagcaactgc caaaaagaaa
    30001 taaacgacga ggattttaca ataagtcaaa tgcctatgaa aataaaaatc gagctggaaa
    30061 gtacaaaaag taacgggtag taacgggtca gtaacaccta gcccgttact agtttaccct
    30121 tactgcccca agggatacag caatttggta acggggtaac accttatttc cttaaaactt
    30181 ttgaaatagt tagctaatat gctggggaat aatgttactg gattttaccc gttacctgtt
    30241 accaaaacgc tagaaccctt gtccccgttg ggattgagtg gtaacgggta cctgttacgt
    30301 aggtgttacc acgtgttacg aatcaaggag gaaagtaaat gctcaatatt atttcaacaa
    30361 acaaagcacc gaactttcaa tatacagatg aaatggatcg gtttctaatg aacacgctgg
    30421 catttagtgt gggattggta acagaagatt attccacatt tgatccagaa gtattaaaga
    30481 taatggaaga agaacctgat tggctgcagg agtcagtagc gtggtgtcaa tcgctagtag
    30541 tgggatcatt ggtagatagt ggcaactatg atgatacagg tgagctaatg gatgaattta
    30601 attgtctgct taacctatat gatcgagcga gacaacgaga gcttacatcg aatgaggata
    30661 atttgttttt aaacatccat gataagttct tggctttgct actaacagat gatgaattga
    30721 taactaattt attggaggta gaataattat gcatatggaa agtattagat acttcgatgg
    30781 tgagaaacac attgagtatt caaacactca agaagatgta gactttatta gttttgagga
    30841 agataaaatc actaaagtta attttaaaga cggaacgtgc ttgaagatag tttcgcctta
    30901 tattgaatac aaatcaaaat gggaacaaga tgattctgac gaacgagatc gctttggttg
    30961 gtaatctatg gcagttaaaa aacaatgtaa tcatgctgga tgtaaaacat tgattgatta
    31021 taggcagaag tattgtggga agcataaagc aaagcaaacg gcaattaagc gtgaagaaag
    31081 aaagcaaagc gaaggtaaat attttcaatt ctatcaaagt agaacatggc gaaaggcttc
    31141 atacttgtat cggttaaatc atccagtatg tgaggattgc ctagaagaag gcttgataag
    31201 gaaagctgat gttgtagatc acaaaattga actaaaagat gattggaata gacggttaga
    31261 tgaaactaat tttcgttctt tatgccatgc acaccataat tccaagacag ccaatgaaag
    31321 acaaagacga gaaaagagta ccctttgagt taagggggca tagtgtgaaa cttactgaca
    31381 atcgatgcct actcattttg gtacaaataa ccgttgtgaa aaggcataag ggtaattaca
    31441 aataacgatt acacttgtaa tcacaagtga aaaagtatat aatgaaagta ggagatttat
    31501 tgaaaaatac aattgttatt actgataaaa cagggaaaca gcgcaccatt gagttacctc
    31561 attttggtca agtgaccatt caaatgcaga acggaaaaat catttatata gataaattag
    31621 ataaagaaaa attctgatcg aaaaacgaag gaatgtgagc ttaattgctt acgttccttt
    31681 ttcttttgtc tgaaaggagg acaacatggg acaccctaaa atattacacg atacaaaagg
    31741 caatatatca agtgaagaaa aagcaatccg tgtggacgct agagaagaat tgttcaagca
    31801 gcaaccatta ataaatatca cgccccctga ctggatggca gcgagcgcta gaagtgaatg
    31861 gaatcgtatc gtaccaacat taaaaaaaga ttatccattg agtgaagcag attatggttc
    31921 attggtagcc tattgtttag cctttgctcg aatgaaaaca gccgaagccg agataagaaa
    31981 atcaggtacg tttatcacat gcgaaaacgg agtaaagaaa gccaatccag cggttcgggt
    32041 tcaatcacaa gctatgagtg atttgaaaaa acaagccacc tcactaggta tgaccttaga
    32101 atcacgatca aaactagctt tgaacaaggt taaaaatgat gaacccgaag acccgttcaa
    32161 agagttgatg aattcatgaa tgattacatt gagaaagtcc tatcaggtaa gctgattgca
    32221 cccaagaaaa ttatccaagc gtgtgagcgt catataagcg atttggagcg ttctaagtca
    32281 gatagcttcc cttatgtgtt cgatgaagaa caagccacca aagcgattaa attcattgag
    32341 ttgctaccat ctacggacgg taaagcaatc aagatgttag gatttcaaaa attcattcta
    32401 ggcagtcttt atggctggcg tactaaagaa gggaattaca ggcgattcaa tcgagcgttt
    32461 accagtatga gccgtaagaa tgggaaaacg tatatcgcaa gtggcatggc tgccaatgcg
    32521 ttgattatgg aacaagaacc agcagaagca aggcaagtat tgtttgtaag taacgctttg
    32581 aaacaagcta aattgggcta tgatatgctg tctaattcac ttagaaacgt ggtcaagtct
    32641 agtaagtttt taagaccaca actgaaaatt atgaactcta agattcagca cttgccctct
    32701 aattcgttcg ctatggcact ggctagtgaa accagcacgc tagatgggtt tgcaccaaca
    32761 accgcaattc ttgacgagtg gcacgaagca aaaactcgta aaacgtacaa cgtcattaag
    32821 tcaggaatga cccaacaaaa gaacggctta ttgtgtgtta ttagtaccgc tgggcttgat
    32881 ttaaacgttc ctatgtacga ggaatactta ttgttagatc gtgtgctaaa aggcgaagaa
    32941 caagccgaca ggtactttat agcgatatgg gaattggacg atcccgaaga aattcacgat
    33001 caagagaaat ggatcaaagc caatccgatt tttgaaagtg aagaaatcaa aaaagtaatg
    33061 attccaacca ttcaagatga tgtgaacctt gctttgaaac aaaataacct taattctgta
    33121 ttggtgaaaa acttcaattt atggagacaa gcgagtgagg acagctatat gattgctgaa
    33181 gactggcagg caaccgaagt agaaccacaa gatattacag gcaagcccgt ttatatcgga
    33241 gtggatttat ctaaaacaga tgatttaact agcgtttcat ggatcgtacc gctagataac
    33301 ggcgaacttt attgtgattc acatagcttt gtagccacca aatatgggct tcaagacaaa
    33361 gaaaagcgcg acggtttgcc ttatcgagaa ctagaaaaag ctggtgagtg ttccattact
    33421 caattagaaa gtggaatcgt ggactatgac caagtatttc agtttattca agatttgatt
    33481 caagaaaatg atttggaatg tatggggatt tgttatgacc cgtataacgc taattcgctt
    33541 atcagtaaag ctgaaaaagc caactaccca atgttagaag taagacaagg aacgattact
    33601 ctaaacgttc cgacccgaac ttttagagaa caagtttatg aaggcaacgt tattcacaat
    33661 aaaaatacga ttctcaccca tgcagtgaac aacgctattt taaaaacgga taacaacggc
    33721 attcagatta ataaatcaaa gaacagtaac aaaattgatc caatagctgc attaatcaat
    33781 gcctatgtgt ttgcaatgga ttacttcacc acaacggaag gagcgaaagc agacaatgaa
    33841 ttttatacaa gtgaagaatt ttctttctaa ttacattcat accgttcttt tacttcttgg
    33901 attggtgtgt gtgttggttg ctatcacctt actaacaaat gtctactatg gcttgttagc
    33961 gctgggcata gtgcttattg gggtagcggt catgctaaat acagaacaga agggaggtta
    34021 aaagatggca ttttttaaag cgagacaaaa tacaacggga gatcctttcc tacaacatgt
    34081 ggtatcaatc caatcggatg attacaccac cagctttaca agcgttcgtg cattaagaaa
    34141 tagtgatgtg tttgcagccg ttcgaattat tgctagtgat attgcttcaa gtccgattca
    34201 attggtcaaa aacaatatgc cacaagctga taatgaactg gtgaagttac taaacgagaa
    34261 acctaattca gaaatggatg gttggcattt aaagtttgct ttggcggtca atatgttgct
    34321 aaacggtaat agctttgcag agattaaacg caacggtgaa aaggtagaag aaattcactt
    34381 attacctaac tcaagtgtaa cggttactca attagataat ggtacgttgt cttatcagat
    34441 tggtgataaa aaaagacgtg tgaagtctag cgatattttg cacttcaaat atttcaccca
    34501 agatggttta acaggattac caccacttta tgcgttacgt gatgaactga aaattcaaca
    34561 agctggcaac cgcacattgc acaatttctt tactcgtggt gtcagtgggt caggtatttt
    34621 gaaggttcat aagtcagatt tagacggatc agcaaagaac gcaattcgtg aaaagtttga
    34681 agaagccaac ggttcaagta gtggagataa tgctcttaga acgatcattc ttgatgaaac
    34741 aatggactac aaaacattag aaataaacac cgatgttttg aagcttatca attccaatga
    34801 ttggaacaca aaacaaattg ccaaggcgtt tggtgtaccg attgagcgtt taggcgttga
    34861 aaatgaacat tctagcaccg ttcaaagtaa tctccagtat atccaaagta cgctgattca
    34921 ttactttaat gtgtttgtga gtgaattaga tacgaaactt gaaaccaata tccgctttaa
    34981 ttccgatcag ttactagaga ctgatcctga aacaaaagta aaaaatgtat tggatcaggt
    35041 caaagggtca cttctcacga ttaatgaggg gcggtcgaaa atggggctac cccccatgga
    35101 tggtggcgat cgtttactag caagtttgaa ctttacgtat ttagatacgt tggagaaata
    35161 tcaattaaaa gaacaggaag gagttacacc agttgaataa tgaagaagaa aaggaaaaac
    35221 ggctgacaga agaagctgag ctaacagccg attctcccaa agtagagaaa gaaaatgaaa
    35281 aacaaccaac agacggcaaa actatttcag gctatgcgtt gaaattcggg caaccgtcaa
    35341 aagatttagg cggctttgta gaagtgatta cacccgaagc attaaaagag gtggatttat
    35401 caaatgtgtt cttattatat ggacacgatt attcaaagcc actagctagt gtcaaagcag
    35461 gtacgttgaa attgaatgtc gatgatacag gattacattt tgaagcagag ctaaccgaca
    35521 cgacctattc aaatgatgtg tatgagaata tctcaaaagg ggttgttgat tctatgtcct
    35581 ttgggttcgt gcttggatta gattcattcg acaaaaaaga agatggcaca attgaacgat
    35641 caatagataa aatcaaagca cttaatgaaa ttagtgtcgt gaccgttccc gcttatgatt
    35701 catcaaatgt ccaagtaaat aagcgttctt acgaatcgtt tatgagtaac aaccaagcaa
    35761 aacaaacaaa caatagctta gaatccactt ctaaagcaca aaaggagagt aataacatgg
    35821 aaaaaacttt aatcgataac gaaaaaacag aattgcgtgg gtatgaagaa tatatccgtt
    35881 cacaaggcga agtgcgtgat ggagtcacta ctgtaaatgc agcggcagtt gttcccgaag
    35941 aagtaatcgg tgaagtcttt gatttgaaac gttcaaatta taacttagct caatatgcaa
    36001 cagtaaaaac agtatcaaat ggacaaggta aatatccagt agcaactaac caacaagcag
    36061 tgttagcaac aaaagctgaa cttgctgaaa ttggtgatat tgacgctgaa atgtttactt
    36121 cagttgatta taaagtagaa actcgtgctg gtaagattgc cttatcaaat gaggttgtgg
    36181 aagattcagc agtgaatatt gtacaagagg tcaaagatca gttagcgaaa ttggtagaaa
    36241 acactgacaa taagcatatc atggatttat taaaaacatt cactaagaaa acggctgcta
    36301 cgttggacga tttgaaacaa ctatacaatg tggcattaga cccagcatta aataaaatgg
    36361 taattctaaa ccaaagcgga tattaccacc tagatacatt gaaagattca gatggacgtt
    36421 acattttaca acccgatgtg acagcaccta gtggtaaatc attattcggt atgccagtag
    36481 tattgattgc agatacattg tttgccaatc ctaaagctgg aacattccct atgattatgg
    36541 gggatattgc acaatctatc tttgttgctc gtagaaatca agtaacgact caatgggaaa
    36601 aattcgatta ctactcacaa ggacttgcag tgatcgttcg caacgattat aagaaaattg
    36661 atcaaaatgc ttcagtgtat attgagttta cgccagttgt aacaccaaaa gtatagaaaa
    36721 atattgggcg gcggtttatc ccactgcctt tttttcatta ggagagataa aatggtaatt
    36781 ttggatagca taaaaaaaag tatgcggatc gatcacacta ttgatgatga ctttattcaa
    36841 caattgattg atacagcagg cgaatatata aaaagtgcta ttgatagtag cgcaacggat
    36901 aaagatatgg ataattatca gcaatttgat ttggcggtgt cattacttac tcaacattgg
    36961 tatttgaacc gtcaagaagc cagcagcgaa cggataccag taacggtaca agcattagta
    37021 caacaaatga gaggtgctta ttatgccaat cattaagaat gtaaatgaat tgactgagag
    37081 agtcaagttt aaaaagacaa aacgggtaaa agatgaagat gggcagatgg tggatagtga
    37141 agaaactgta tttgaatgtt gggctaatgt gcgttcacaa atgctaaaag acgtgcttgc
    37201 tagtgtaggt accattcttg aaggaacgtt gacgtttatt attcgatacg atcaagatta
    37261 tgaactaaca aacgatatga aagtagcttg gaaaaacaag agttataaaa ttatttcaat
    37321 caatgaagga acggcgttta aagattatac aacgatcata gctaaacaga tttcttagaa
    37381 tgattacact tgtaaacgtt gtgggtattt agtataatta aggtagtaaa tgaagggtta
    37441 gctgcctgaa ttttgcaaga cttagctagt cgaaatctat tgttggactg aaaattgtag
    37501 gtgtggttgc aaacatgctg gactaagaaa gatgatagat gatgaacgtt caattttaat
    37561 acaggcatgc taggactgat tggatggttt tggcaagctg attgtgtaga aatcaaagaa
    37621 cacgtctgtt gtggacgtgt tttttttgtt ataattcaaa agaggtgatt taatggacaa
    37681 agcagagttt acaaattttt attggaagta ttatctacat ttagaaaatg agtttattaa
    37741 taccacagat tttgtgatgc tcgatgagaa taatttcaaa acattctcta ttgaatatca
    37801 aaaactacta ctagcgattg gttcggagtg tgagattatt ttcaaagaac tttgcggatt
    37861 tgatagcagt agcaataaaa gcataactga ttttaaagct gttattaaat ctagcgaatt
    37921 aatgtgtttg gataatggtg ttagggttat gaattcttta acattgactt cactaaaacc
    37981 ttttggagat gggtggcctg aagatacacc agattggtgg aaaatatata acagagtaaa
    38041 acatggtcgt tcttcaaatt ataaggaagc aaatttggaa aatgtgttgt atgctttagc
    38101 aagtctatat ttattagagg aatatttgca taagaaagta atactagaag gtgaagtaga
    38161 ctttataagt ccagagtcaa atctatttac gttatcttgg gaaagaaaac attcgtcgat
    38221 gcaaaaagtg acgtttgaaa aagtggattc aaattatgta gctccactca ttgattttaa
    38281 agaacaagaa gaaatttaaa aacccccacg gcttattgaa gtttttgtat gccatattgt
    38341 atgccatttg gtttaaatcg cttgaaaaat agtgatagat aactctaatt catttagtca
    38401 taaacgctgt tttgataacc tttatagttc tttgatatgg gtttctcatt catggcggaa
    38461 gaagaagaat agaacaaaag aatgaattaa taagatataa aaaaagggat tgtgacaaac
    38521 gtcttgtcac aatccctttt tccaaataaa cgatgttcaa tcagctgccc ctcggcattc
    38581 gctcgaaaaa cggcgaaata tgaagaacta ttttgccatt tgtttctcta ataatcaggt
    38641 caaaacgttg acttcacagt ctcttcctta aacggtgttc tcctgccaac tcctcggtca
    38701 caagtcacaa tattcaacaa acatgagaag ctgttttttg aaattgttcc ttgtgactcg
    38761 gagctgaacg gcaggctcac gacctctttc ttaaacggtg ttcaaaagct tgcatctgcg
    38821 gtaataagtt caaccaaacg aaaattatga ggagctattt ttgtttggct gttcttatta
    38881 cttgatgcag gacagctttt tcacaacctc ttttcgttta gcactaaatt tccttaaaaa
    38941 gtagaaaagc tttcgaagcc tcgtttgttt cttttactgt ataataaaag aaaagagtaa
    39001 caatcgctaa aagatataaa caagagaaag gaaatacaag atgattggtc tgatttattt
    39061 tgtggtgatc gttctggcga acacagttgg cgctatttcc gggatgggtg gaggcgtgtt
    39121 gatcaaaccg attcttgatc ttatcggcgc ccattctgtt gcagggattt ctttttactc
    39181 aacagttgcg gtattcacga tgtccattgt ttcgactgtg cgacaagtat caagcgggaa
    39241 atcactgaat tggcagattg tcggttgggt atctagtgga gctgttgttg gaggagtagt
    39301 cggcaacatt gtattcgaag tttttttaca gttatttgaa aacgagaagc atgtgcagct
    39361 gatccaaatt tttttgacgg tattgacctt ggtttttgcg ttcttctaca ccaagcatca
    39421 tcagccaaaa tttcatttga cgtcatggac ttggtacctt atatgtgggg gggttctggg
    39481 ctttttagct agttttttag gtattggtgg tggaccagtc aatgtttctt tgttgatgct
    39541 gatgtttgca ttgccaataa aagaagcaac actatattct ctatctacga ttttcttttc
    39601 tcaactggca aaattggtaa cgattgcttt aacaagtagc tttatgcgct ttgatttatc
    39661 tatgttgttt tatgttatcc ccgctgctgt tattggaggt ttgtggggag caagatttag
    39721 cagggttttg tctccaaaaa aagtgacctt tatttttcaa gtaattgtcc tcgtggttct
    39781 tttggtcaat tgttacaatg cctttgtcat cttacaaaca ttaggagaat ctagactaac
    39841 gcaagtcaaa atcactgaaa catattgttc taaatgaaaa aaagagtata ctatgataaa
    39901 aaaattcatt ttaaaaaatc agaaattggc tggtgatttg gatgttacgg gaaatgcgtt
    39961 tagaagatgc agaagcacta cgtgaaatca atgcggatca attagggtat gatataccat
    40021 taaccgttac ggtgagacaa atgaagaaac tgctgaagga gccagagaaa aattttttct
    40081 tggtttatga agatcctact tctaaaaaag cagctggcta tgtacaagcg gagtcctatg
    40141 aatcgatttt tagcgatcca atgttcaata ttatggcact tgctgtgtct aaatatgctg
    40201 aaaaaagagg catcggaaag gctttgatga ctggcgtaga agaagaagcg aaaaaacgag
    40261 gaataacgac aataaggctt aattctgcag aatacagagt agaagcacac caattttatg
    40321 aacacatcgg ttatcattcc gataaaatgc aaaaaagatt tttgaaaatc ctgtaaatct
    40381 ttatcaaaaa aatacccgat caccaagccg atacttgatg atcaggtatt tttgtttttt
    40441 tgactaagaa agtaattgca tcaagaaacc agagatgatc aaaacgatgg caccaccaag
    40501 tcgattgccc atttgagcaa aagcaataag ttccatccga ttagctgcag ataagacggc
    40561 tacatttcct gttccgccca tcgagttgtt gcataagcca gcagtaatag ttgattcaat
    40621 tggatataaa ccaaacaaac gaccgacaaa tcctgaaaca actgaaatcg cgataacact
    40681 tgtcagacat aagacaacaa attgccatgt caaagcagaa gctaatacat tcagattcag
    40741 caacgcaata ccgataccgg caagaacagc tgctgtcaag tttttgacaa tcaagttatt
    40801 gaacatgata gctgcatctt cataatactc tggtaatagg ttggcgattt tacagatgac
    40861 aacgataata atcataaatg cgtaagcatg gactttagga acaaaatagt taccaatttg
    40921 tcctaagatg aagaaagtca atgataccat caaaccaaca cctaactgtg gaatggaagg
    40981 tttcacagtt cgaggttttc catcgccaag atcgcctttt tccattaatt taccattgcc
    41041 gttgaatttt ggcattgatt gtccagcacg agcaactaat gctgcaccga tgatagctaa
    41101 gacatttgtc attgctgtcg caggaatcag gcgggaaatg atagaagaag catccgtacc
    41161 taaaacattt gcataaatcg ttgataaagg aacggctccg gctccaacac caccagccat
    41221 cgcaggtaat gagatgtata aaacggaatt tgcaaaacca tttccgataa gcatgcccac
    41281 gagtcctacg gcaaaaaagg agacgaccat tgaaataagt gcaacgggaa taaaacgaac
    41341 agaagctttc atcaatagat tacggttcat accaaggatg ctaccagtaa tcaaggcagc
    41401 aatataaaag tcccaaaagc ccatattgct gacaaagttt tctgtggatt tcactacata
    41461 ttcaggtaag atcccaaatg tagcaatcgc agcagaagcg aagatcgcaa aaacggaacc
    41521 accacccaaa taacttttga cgatagggat ttttgtcccg ataaaatgaa ataaattacc
    41581 gaaaataacc aaaactgcga ttggtccaat catattcgtc ggtaatttcc ctaaagccat
    41641 tgcaatgatc aggacaagga ccatgatcaa ataaagtggc aaacttacgc cggtgatttt
    41701 tgtggaccaa aaaccttctt ttttcttttc ctcaactgca gttgcagttg ttgttttttg
    41761 tgccattttt acagatcctt tcttattctg tatcatatga aaaaagccaa agaaaagcga
    41821 caaaagagca ggagttggct ggccgctgtt ttgccgcagt cgcttttttc tttttagacg
    41881 tcatacaaag tttctgtatg ttcttttact ataacgatct taatcttcta aagatttata
    41941 ttcaggaacc catttagcag attcaactgc ttctttgata tccgtgattt cttcacgatt
    42001 caagttttgt gcgacaactg attttgcgac agtttcagca atcgtttgag aaaattcagt
    42061 gatttttgct actggaggca agatagctgc tcctggtttt gttacatcaa cgattccgcc
    42121 taatgctcga ctagcttgag aaatgatttc agcatttact cgtgtagctg ttgaagcaat
    42181 caaaccaagt cctaaacctg ggtacatcaa agcattattt gcttgaccga tttggtaagt
    42241 tacaccatta tattcaacat cagcagcagg gatacctgtt ccaactaatg cttttccgtc
    42301 cgtccattct attaaatctt ttgcttttgc ttctgccaat tttgttggat tagacaaagg
    42361 catgatgatc ggacgtggtg tatgagcagc catttctttc acgatttctt cagtgaatgc
    42421 tccaggttgg gtagaagtac caatcatgat tgtcggatgg atcgctttta caactgcttc
    42481 taagtttgtc aattcatcag cattagtgaa atctgagcgt ttgcgagcga atgggatttg
    42541 accaggagtc aatccttctg tatcttcaaa caataaacct tgtttatcta cttgatagaa
    42601 atgttggcgt gcttcttctt caggtacacc ttgacggatc atctcatcta aaaggatgtt
    42661 tgcgataccc acaccagcag taccagcacc aaatgtcaaa attatttgat ctttcaattg
    42721 ttcaccggat atattcaatc cgcctaatac acctgctagg acaacaattc ctgtaccttg
    42781 gatatcgtcg ttgaaagtag tgatttgatc ttcgtatttt tctaagatcg ctgcagcatt
    42841 tcctcgtcca aaatcttccc aatgcaataa caattctggg aataattcgg tagctgattg
    42901 aacgaattga tcgatgaatt catagtaagt ttcgccttct acacgagcat gacgattgcc
    42961 taagtataag ggattattca ataattcttc attattagta ccagcgtcga tcgatacagg
    43021 caaaacttgt gctggattaa taccagcagc agcagtatag accatcaatt tgccgatagc
    43081 gatgtcaaca ccgttcacac cccagtcgcc catacctaag attccttctg catcagtcac
    43141 aacaatcaaa cgaatgtctc gtccatctgc cgcgttcttc aaacttgctt tgatgttttc
    43201 tggttcgtcg attgaaagaa atgcagcatc ttgcggtttc aagaaaattt cgttgtattg
    43261 ttcgattgaa tccgcaacga caggatcata aacgacaggc atgaattcaa ctaaatgttc
    43321 gcccatcaat ttataaaaca atgtccgatt cgtattgaat agattcatta agaagatacg
    43381 tttttccaaa tctgtttgtt tgcttaagta ttgaccataa gcttgaacag attgttgttc
    43441 cagtgtttgg acagtacttg gaagcatacc agtgattcca tattttgccc gttcttcttt
    43501 tgtaaaagct gttcctttat ttagaaaagg attatttaat aagtttaacc ctgtaagcat
    43561 gaatgattcc tcctaagttt taatacaaac gaagtataga agtcagatga tgatatagtc
    43621 aaaaagagca ggtatgataa attttattta tatgtaatat agccaaaaga aatcaaaata
    43681 gcagtatttg ttctttttat atcgacaatc cttgcttgaa tactatgcgt atctcttata
    43741 tgctagagaa agaaaagtag aagaataagg gatagatgga atggataaat aggatttctg
    43801 aggaaaaaag cacatgatag cgttgatagg agtcacctat gtcaggtgat aaaaatacat
    43861 aagtagaaaa ttaagaggag gaagagaaaa tgaaagaagt tcaattgatt agaaaaagcg
    43921 aactatcaga aggcggttgc aatgcatgtg gcgtagtaga agcgacaagc tatacattaa
    43981 aattagattc caatcaagca ataatctctg aactgacagt aggcggtctt gtggacagtc
    44041 tggcgcttgc tgaaggtttt actggagaag atatttatga gatgttttca gaagtccgtc
    44101 agttaaaaaa aggagaaaaa tgcatagagg ttcatcatga gagcccgaat gtgaggttca
    44161 aacgtggtga taatgagatg atcttcaaga atcatgtgtc tgatcacact gaactatatg
    44221 aaatcgtgaa tcaaatactg tctgggattt ttgaattagg accttatgag ttcaaggaag
    44281 aaaacggtaa tccaaaatta aatgaagaat ggcaagaaac gattgaaaca caaagaaaca
    44341 atccacactt atttcaatag tcttccacag tatttcgtaa aaatgttgat gaaaaagaaa
    44401 caccgtgaat cagaggtcgt gaaaaacctg ccctgcatca agtaataaga acagccaaac
    44461 aaaaatagct cctcctattt ttcgtttggt tgggcttatt accgcagatg caagtttttg
    44521 aacaccgttt aaggaagaga ctgtgaagtc aacgttctga cctgagtatt agagagacaa
    44581 atggcaaaat agttcctcat attttgccat tttttgagct aataccgagg gtcagctgat
    44641 tgaacaccgt tttatcgaga ggttgtgaaa aagtcgctta gtttcgagta gtaagaaaaa
    44701 ttttgtgaaa atggctttcc acatttttgc ataaatttga cttaataccg agaaaatggc
    44761 ttttgaacac cgtttattca aaaaaaggga ctttgacact acttttgtca aagtcccatc
    44821 ggttttttat ctatttttat tacaatcatt tcttccagag tagtgacatc tggaatggct
    44881 gaaatgtaaa cagattattt gcctgtatca atgtcgaaga gtaatataaa aagtgtaaac
    44941 gctatcatat tgttcatcat tcaaatttta tagagagaag gcattgagat ggaaaaaaca
    45001 tatcaagcag gtacaaatga aggaatagta gattttatca atatggaaga tttagaaatc
    45061 gcggcttcac aagtgattcc agctggtggt tatggttaca tcagcagtgg tgctggcgac
    45121 ttatttactt atcaagaaaa tgaacgggca ttcaatcatc gtttgattat tcctcatgta
    45181 ttaagagatg tagaattacc cgatacaact acacattttg acgaagaaat gctgactgca
    45241 ccaatcatca tggcaccagt tgctgctcat ggattagctc atgtgaaggc ggagaaagct
    45301 tctgcaaaag gtgtagcaga ttttgggacg atctatacag caagttctta cgcttcttgt
    45361 actttagaag agataagaga agcaggcggg gagaaagcac cgcaatggtt tcaattttat
    45421 atgagcaaag ataatggaat caatttggat attcttgaag tggccaagcg taatggagca
    45481 aaagcaatcg tattgacagc ggatgcaaca gttggcggaa accgtgaaac agaccgcaga
    45541 aacgggttta ccttcccgct gccaatgccg atcgttcagg cttatcaatc aggagtaggc
    45601 caaacgatgg atgctgtata taaatcttcc aaacaaaaac ttagtccaaa agatgtagaa
    45661 tttatcgctg ctcattctga tttgccagtc tacgtgaaag gtgttcaatc agaagaagat
    45721 gtctatcgat cattagaatc tggtgctggt ggaatttggg tatctaacca tggtggccgt
    45781 caattagatg gggggcctgc tgcgtttgat tcgttgcaat atgtggcaga agcagtagat
    45841 aaacgtgtac caatcgtgtt tgacagcggt gtacgacgtg gacaacatgt tttcaaagca
    45901 atcgcatcag gtgccgatct tgttgctatt ggcagacccg ttatttatgg attgtcttta
    45961 ggaggaagta caggagtcca tcaagtgttt gatttcttta aaacagaatt ggaaatggtc
    46021 atgcaattag ctggaacaca aacagtagaa gatatcaaaa aaataaaatt gcgtgagaat
    46081 cgttttattt aagaaataaa tgacgaaaaa aataggagtg cggcagatga tgccgtactc
    46141 ctatttttat agttcaagga tgtcactaat agaataattt gaaacgaaaa aataaaattg
    46201 aaatattgtt tcatacttaa taaaaaagga agaatattca tgtaaacgat tttattgttt
    46261 ttttctcttt tatacaaaaa gggtcataat ttcaagtaag cggatgaatt catgaggatt
    46321 ttttgcatac tgtctctact atacttaggt cactaagaaa aaggagtgat ttattatgaa
    46381 aaagaacatg attgggacat tattactttc aacacttctt ctaggcggct tggcaacacc
    46441 agcttttgct gagggtcaag cgacttcaaa aggagatatt acctttactg aaccaacaaa
    46501 taccgttgag cctcttaacc ctactgatcc ttcaaaacca gtagagccag cagatccgga
    46561 aaatccagca actggccaga caggttcttt aacattggat gtagttcctg aattgccatt
    46621 tggtacacac gagattgaaa gcggaacaaa aacgtatcaa gtagacgctt caaaaaacga
    46681 tacaccttat ctccaagtat cagatcgtcg aggtgtaggt gcagatggcc aagcacaagg
    46741 gtggaacgtg acagtttcgg tttcagattt tgtaaacggt tcacaagttt tgcaaggcgc
    46801 tgaattagat tttggaacat ccactgttaa aagtacgtca gataacgaat ccactggacc
    46861 aactagtcaa actgtaactg ggttgagtaa agcaagtgca gcgacaccaa tatttacagc
    46921 agcaaaagat caaggtctgg gaacatggct ttctgtttat gatccagcaa atatcacact
    46981 gaaagtgccg aaagcagcag ctggaacatt cacggctgat ttgacttgga acctcgtggc
    47041 tggcccagta gcatagagta tgaaataaat tcaacaaact gcggtgaaaa tactataggt
    47101 gaaggatttt ttaccgcagt tgttgttgaa aggatgtggt ggacaatgaa tcaaagtaaa
    47161 cgactgtttg tttcgttttt ttctatttta agtctatttt tcatttttcc gtcaatcagc
    47221 caagcaaagg attcagcagg agactttgga atcaaaccgg tatttccaga gaaccaaata
    47281 gataaagcaa tcggttattt tgatttatta gtggcaccgg aacaaaatca gacactagaa
    47341 gtaattatca gcaattcttc agatgaagaa cgaacatttg aggtctctgt caatccggcg
    47401 gtaacgagtg atggtggaac gatcgattat agtcaaaaaa acccaacgtt agatgagaca
    47461 ttgccgtttg atgtccgtga cgttttgctc attgcgaaaa aggaaatcaa tgtatcagca
    47521 catgcagaaa caactatacc tatagaagtg aaaatcccag caaaaagctt taagggacgt
    47581 gtattagcgg gtattcatgt ttcacctaaa gaagaagctg aaacagaaaa tgctacagaa
    47641 ggagcacaaa tcaaaaatcg tattgcttat aatctcgcag tcgttttaca agaaagtcaa
    47701 gagacgatag aaccggatct gaaactttta tcaggagatt tggacgaggt caacgcaaag
    47761 ccaactgttc agcttcgttt ccaaaatcct cagcctagga ttatcagcaa tttgatattt
    47821 acgagcaaga tcttttatga aaatcagctt tatattgaaa atacgtctaa tgaattttta
    47881 gttgcaccaa attcgaattt tcacttgaat cttgatttag ctggtgataa agcaaaagcc
    47941 ggcgattacc gcgcagaaat catagcaaaa tcaggcgaca gtaatgaatg gcgatttaca
    48001 caaaacttta cgatcaaaaa agaaaaagca caaaaagtaa atgaaaattc cgtttttgca
    48061 gtacaagaac aatctttccc atggctttat gcaggattgg ttgctgcagt tctagtgtta
    48121 tggttgattt tgctgttttt gtgggtccac aagaaaaaga aaaaaggaga aacaacatga
    48181 tgaggtgatt tcgttgaaaa catcgatctt attgggaggg attattgcaa gtttgctgtt
    48241 cttcagctgg caagagccag tccaagcaga taccaaaagt tcaggtacga ttacatttta
    48301 tgatctaagt ccagttccgc atccaagtgg ttcagtcaat ggcgcatcaa aacagcagac
    48361 acagctaccg atttataaag aatctaatca acatggcgta ttcccggaga cgaatgaaga
    48421 aaagatccgt tttctttatt tgatcattgg tatagaatta tggcttcttg cgtggttgtt
    48481 gttatggaga agaaaggaaa aggaggatga acatgttgct acaaaataaa ttttcatttt
    48541 ttcgctcctt cttttttact tcgctttttg ttttaagtat atttatcttt tcaccttcgg
    48601 cagaagctgt tggagcaacg cctcctgcca tttcttatga tccatacacg tatgaaaata
    48661 tcgtacctcc aaatggtgga cgtagtgcag tcaatggcgg gaagcttgtc caactaactg
    48721 gggctaacca attgcctaaa ttgactgcta cttatttgaa cgatggttca aatgatcctt
    48781 ggaaaggtgg cacggtccgt tttcattggg aaagccatgt gaaactaaca aatgtacttg
    48841 atttggtgaa tatcactgca caaggatttg catttgtggc gatcatcaat ttgccggaac
    48901 atgtatcaag cagtgatgta ttaaaagcaa ttgactggaa caacgcctac ttgtatattg
    48961 ccggtgcccc catcaaggtt actagcggta gtttattatc agcaggaagc cataccttgc
    49021 gttttgggat ggggtcgtgg gatacaaata ctctattggc agatattatt gctattatta
    49081 cgcgaggcga attcaacgtg gacgatatcc cgcttcaatt tgatgttaca gctaatgtcg
    49141 cgaagatgac agaaaacgga gataaatatg atacgagtcc aaacaaaatt ttgaccaagg
    49201 gtaaattaca accttctatg tctaaaaagg ccgttttttc tgttgatttt tatgattcga
    49261 ataatattat ccaagatcgt atgttcaatt cgattttagc tccagctgca ggtagatttt
    49321 atcctaaatt aactggcgga aacttgaatc caggagcata tgcattttct gcaagtgcag
    49381 agataaatac gtggaatagt tacatctcaa caagtgattc aacaggaaaa tataatacat
    49441 ttgctgatac cacagaatac gtggatggaa ataaccagaa ccttccaggc tctaccaata
    49501 gtcggacatt gacgatgggg ctgactgaag gacgttttga tcagttgcca tttagtcgct
    49561 ttgatcgcgt agtcaactat tttacaggaa aaaacgttac acaaggagca atactgactc
    49621 atactccagc aagcacaagt ggattgaatc agacagccaa tatcgtgtac agtgggaaag
    49681 atgcgcaagg cggattgctt tctcctgttg ctttaaaggt attggagcag tacaagctag
    49741 acggaacggt tttaccaaca aacttaacag ccgatagtca gtggggaaag ctcctttctt
    49801 ctgcatcgta ccaagtcacg gccaattggt cagcaactga actaaaaaag ggttcgatcc
    49861 attacaggct ttattcgaaa ggaacccaaa aattagcgac aggatggaca gatcaacttt
    49921 tccaaacgat ccaatcaaat aacgggggtg taaatacagc tacttctaca ctacctgcat
    49981 tggcttcagg gcaatattat tttgattatc gcttggtgga cgatgtactt actaacatgt
    50041 atccgtcttt tgcgtacaaa tggcagtctg aacaagctgg aatcaccact cttcctcaaa
    50101 taacagtggc taattttcca tctgtgagtg cagatagtca gctaaaaaac cttagcagac
    50161 aacctgagac aggagatccc ctgtctgctc tatcaggaga tacgattcaa gaaaatgtga
    50221 cattcacgtt aacaaaatct ggggatgcga taaccgacaa aaaaatcacg atctcacttc
    50281 ctgaaaatac tacttatatc aatggttcct taaaattaaa tggtacaact atcgcagata
    50341 ccggcattca acaaggagtt tctgtcccag cagatctatt gagcaaaata ggagatacca
    50401 ttcatcttac ttacaactat caattaaata ctgtagatac ttctgtacaa tccgtcagca
    50461 tactgacaaa ggcagctgta ctttccagca atattacatt agcagatggt gctaagcttc
    50521 ctaacccagt tgtccaaaca tctgctaaaa caattcttgt ccccaaacaa gaattaacat
    50581 tagttaatgt accagatgat tttacatttg gtaacgatct ccccaaaccg ttgaagacaa
    50641 gttattatga agcaaaaggc gatttttctt ttgatgtgcg ggatactcgg cttccaagca
    50701 cgtctccttg gcaactgaca gggacattga cttctttatt taagaatgat caaggtcaag
    50761 aattaagcgg aacaaaatta tacttcaatc attctggatc aaaacaattg attcagcaag
    50821 gtcaaaacac gttgatttat gagagtgatg gaacagctaa aggagaggtt ctcgttgact
    50881 ttcccgatac cgatggttta ctcttagagg taaatagcag tacgaatgct caacctggcg
    50941 caacgtatca aggcatggtc acatgggaac tgacagctgg gccaaccagc taagtgatta
    51001 gaatttgtat ggatctgtga taactgtcac agatcctctt tttcaaggat gagaaggaaa
    51061 cttctgctgt taaaatcaga aatgcttgga ggagtggact tggaactttt cagtttgctt
    51121 gaaaaaaatg aacaacggca aatcaaactt ttccaacttt tattagagga aaaaggagag
    51181 atttccgtta ataacgtact tacccgctta tcagttgatc gggctacctt gaaagaagat
    51241 ctgttttatt tacaagctaa cttggaaaat atcaaacaat tggaaattgt tatccaagaa
    51301 gggaatattt tattaatcag acatggaaat atagcagcag tcgatgttta ttatcattgc
    51361 tacttgcgct attctacaaa atatcagata cttctttatc tgttggaaaa tggctcattt
    51421 gatcggcaga aacttgtcat ggaacttaat atcagttcgg ctactttgtc tcgcagagtg
    51481 aaggaattaa atgattcttt aaatgagttt catctgaaaa taaaaagcgg gcggctgacc
    51541 ggtccagaaa gtcaaatttg ttatttttat ttccaattat tttggtttgg acgtccttat
    51601 cttgaaaaca aaaaagaata cagtgattta tcaggaaaca cttttttaga tctgctgcaa
    51661 aaagagttta gttttactat tacagaagaa ggacgattga aatttgaaat atggctttcc
    51721 attatgaaga agcgaatgcg ctgtacgaaa aaatccaaac cagattatag caatcttcct
    51781 gttggattgt ttcaaacgac acaattttta ttggacctcc atacattttt gacccgttac
    51841 ttctttcaat atgcctttcc ttggaatcaa aatgaaacgt tggtttttta tcttttcatg
    51901 atcagtaact ttacattaga tacacataac tcgcatgtcc aggagttttt gataagcgaa
    51961 aaatacaaag acgacgtagt agctcaattg aatcgaacgt ttaaacaatc gatagaagaa
    52021 tatttctctt tttatgtttt tccagaagag atttcgcaaa agattgcgtt gacagtgatg
    52081 caaaatcacg ctcattttgc ctattttaga ggatggatga atatttttgg ccaagaagga
    52141 ttaaaacagc ggttaactga agtagaagat aaacaattcc tggttttatg tgaaagattg
    52201 gtcagacaaa catttgctat tgttgatttt actgaagtag acgaggaaaa tgcccgcttt
    52261 gaattatttg ctcgctatgc atctattttg cggacgctga tcaagcagtt agaattacgt
    52321 ctgcaaattg cttatgatct tccttatgaa aggctaatgg cggatatcgt gaaagaaatc
    52381 atccaggaac aattgctgaa tacgatcaaa tatgatttag tcgaatacga gaaagaaaag
    52441 cagtatgata tcattttgac tagccaattg aaagagtacc cgtcacagaa gtccgctaaa
    52501 gtttttgtat tcactagcaa cgaatataat tatgatttcc cctatttgaa ccaattttta
    52561 aaagaatgtt atttagaaaa attgaattta aggatgaata aaacatgaaa atcgtgatca
    52621 ttggtgcttc ccatgcaggc atcacagctg ccctaaatct aagaaaactt caaccgaaag
    52681 cagaagtttt actgatcgat gaagatcata aagatggact aggctatgtt tcaaatggaa
    52741 tcaaccttta tttaaaagga aagatacgta gtttagctga agttgcccat aacatgcgga
    52801 ctcttcaaga aagtggggca aaactgatca ccgaatggag agtaactgaa cttgatccag
    52861 acaaacatca gctcatcctc gcatccaaag aaggaaaaaa cgagaccata acctatgata
    52921 aattaatcgt agcaacaggt tcctctcctg tcaccttgta taaacaaatt gaagctgaaa
    52981 atgtctacac ctataaaaat ctagtgcaat ctaagcaagt acttgccgct ttaaaagaag
    53041 caaaagaagt agtgatcttc ggtgctggtt atattggatt ggaattagca gatgctttga
    53101 gaaataaagg atacattatt catctagttg attatatgcc gaatgtttta tcaagatatt
    53161 tcgataagga tatgatcaac agttttcaaa atcagctgca aactaagcaa atcaattttt
    53221 atccaaatga attcttgatc gattggaaaa aatcagaaga gaaagtagta tccgtacaac
    53281 ttctatctca agcaataaag gcagatatgg tcattttttc tgcccaaact cgtcctaata
    53341 cgacattgtt aaaagaaaaa gtggctttgt atgaggatga gactgtgata gtcaatgaat
    53401 atctgcagac aagtgatccg gacatctatg cgattggaga tatcgtccca gtcagttttg
    53461 acaaaaataa acggcatctc tttttacctt tagttactcg agctgtacat atggcaagag
    53521 cagtagcgct aactttgagt ggtcagccaa ccgcttacga cctcagacaa aagataacag
    53581 cagcagtcat tatagactac tttttaggaa ctgtagggct gacagaagat gaagcgccat
    53641 tcttggaaca aaataccggt tcgtgttcag gagaatttga tctatttcca caatacgatg
    53701 aagaaaacaa aacagtaaat gcaaagctga tctaccatcc ggatacatta gaaataattg
    53761 gcggacagct gataagccaa gaattcttat tatcagattt gaacctgctt gcggatatcg
    53821 tgaaacacaa aactacgatt ccacagctag cagttgagga ttttggattt ctgtctgaac
    53881 acacctctcg ttttcactac ctcaatgagt tagcttttaa agtactagct aagagagcaa
    53941 atagcaatag agtagataaa agactgtgag aaatatcacg gtcttttatt gtgtggggat
    54001 ataataaata ttaatcaatc gagaataaaa aattcatata atgaaatagc ggaagaattt
    54061 tttgagcata atattcgcca aaaatttatc aagtgataaa attgttgtat aaaatgatta
    54121 tttcaggagg aggagttaaa tgtttttagc attaaatgaa attatgcatt caaagttacg
    54181 ttatgcgtta gttgcagggg tgatgttttt gatcgcctac ctggtatttt ttttgactgg
    54241 gttagcttat ggcttagctc aagataatcg aacagcagtc gacaagtggg aggcagattc
    54301 gattgtgctt tcgaaagatg caaattcaaa tctagggatg tccatgatta ctaagaagat
    54361 agcagaagaa gtcgaaggtg ggaaagtggc gtatcttgcc cagacacctg gagtcgtgac
    54421 tagtaaagac agtacagaag aaggaaaaat caatgttagc ttcttcggta tcgataaaaa
    54481 tcaattcatc atgcccaatc ttgttgaagg aaaagctttt gataacgatg atgaggcagt
    54541 aggcgatatt agtttgaaag aagaatatgg tctagccgta ggagatacag ttaagttatc
    54601 tggtagtgac aagacgttta aactaactgg ctttacggat catgccaaat tcaatgtctc
    54661 accagttctc tatacaacca tcaatgctta ccaagagatc cgcttcgaaa aagaagatac
    54721 aagtgaaaat gcacggatta acgcaatagt tgtcagaggt aaaatcagta atttacctga
    54781 agatttagaa cagatcaaaa tttctaaatt catcaatgaa ttacctggat ataatgcgca
    54841 agtattgact tttggattta tgatcggatt tttgatcgtt attgcggcta ttgtgatcgg
    54901 gattttcatt tatgtactga cgatgcaaaa gattaatatc tttggtgtaa tgaaagcaca
    54961 agggatcaca ggaggattta ttgcgcgttc tgtagtggca caaacattca ttttatcatt
    55021 tgttggtatt cttcttggtc tattaggaac agtgggaaca tcccttgttc tacctgatgc
    55081 ggttccattc caaagcaatt ggctgttttt tggcgtcatt agcttgttga tgctggtagt
    55141 agctgtgtta ggcgcactat tttctgttcg gacaatcgta aaaatcgatc cgttgaaggc
    55201 aattggataa gaaggaggaa gagcatgaaa gcaatagaat ttaaagaagt agaaaaaagt
    55261 ttccaagatg gcgaccaagt agttaaagca ttgaaagaaa caaccatgag tatcgataaa
    55321 ggggaatttg ttgcaatcat cggtccttct ggttcaggta aaagtacttt tttgactttg
    55381 gcaggcggat tgcagacgcc tagcagtggc tctgtattta tcaatgatca agaattcagt
    55441 aatcaaaaag aaagtgaacg cgttaaacta cgttttaaag aaattggctt tattttgcaa
    55501 gcttccaatc tggttccttt tctgacagta aaaaagcagt tattattagt agataagatc
    55561 aaacatgaac atcgtcaaaa agaagcaaaa gaattatttg agcagcttgg cgtggataag
    55621 ttgatcaaca agtatccaga agaactatct ggtggagaac ggcaaagggt cgcaatcgct
    55681 cgtgcattgt acaatgatcc gtccattatt ctagcagatg aaccaactgc tagtttggat
    55741 tcagaaaagg cacgagaagt agtcgatatc ttggcaaaag aatcaaaaga caaaaataaa
    55801 gcaacgatca tggttactca cgatacacgg ctgattgaca aatgcgatag aatatttatg
    55861 atggaagatg gtgtattgaa agaaaaagaa taaccaaaaa gcaggtggaa aaatggtcca
    55921 tcgatacaac aaagatacac agcaaaaaat tttgaaagaa gcgactgact tgtttatgtc
    55981 caagggatat ctcggcactt caacaagaga gatcgcacaa aaagttggga tcacccaacc
    56041 caatctctat cattatttcg gtgataaaga aaaactatat acggcagttt tagaaaacca
    56101 cttaaaagat gttggaaaag ctttgagaga aatcgttcaa acaagcgaaa cgggatttca
    56161 agtaaccttg acaaaaatgg cgcagttttt gattgagaca catctggtcg atttgtttct
    56221 gatgcttcac gatcttgaaa gcaatctttc aaaggaaaca agagatcatc ttttctttct
    56281 atggaagaaa aattatcgtg aaccttttga agaaatcttt tcagcaaacc aatctgtgct
    56341 aagaaatggg atttcaaaag aaatcgcagc aaggcatttt ttcttagtgt tagcacctta
    56401 catcactcgg tcgaaaagac ctgtggaaga accgctaaat gtggcgcaat tgatcgattt
    56461 atatttgaat ggtgtattag gagaagcgta aagctgttat atagggagaa aaatagttag
    56521 gtgaagaagc aagatatgac gaagatcgtt atatcttgtt ttttttatat aggtagtttt
    56581 tcataaatac aaatttgtta ttctctcatg attatcaggg tatattttta tttattatgt
    56641 cggtgttcca ggaagtgttt taatttaata acgaagaaat taattgtttg tagaatgaag
    56701 gaaactattt attgggtaga tgaatcacca cgaatagtca aaaggagatt tcaggatatg
    56761 ccaaaaatga aaaaaatcat tttagcagta atgttatttt ctacggttat atcttttaca
    56821 gccccttttt tgcgtactta agctgatttt aagttttgac ccttagtctg gatctacgag
    56881 gtgagagtca agaatgaaaa aaataattgg agcttttgta tttgcaatca ttatcattat
    56941 tatctgtttt caaatagatg tttttggtca aaaaaagata gttggacaaa cggtcagcag
    57001 tacgaacagt acggttacaa agacaaagga atcatttgat gatacagaac aagagacatt
    57061 aatcaaaatc ggaaaaaatg accgtacact atatacagat gactcgctaa ctaccccact
    57121 tgcaactata aacggcggag agctggcgga gtttctttct gaaacaaaaa atgcttatca
    57181 gatcaagaca aatgatggct atactggata tttagccctc gaagatggaa ccaaagtcac
    57241 aaagaatata caaacaaaac cggaagagct atctgatgca gtgattgtat tagatcctgg
    57301 gcatggcgga aatgatactg gggcattaag caatgatgaa caaacagaag aaaaagatat
    57361 aacattaagt acagccataa aagtaaaaaa ggcgctagag gatgctggag caacggttta
    57421 tttgacccat actacagatg aattagtaca gcttggagat atatgcgact acagtgaaga
    57481 aaaaaaggca gatgtcttta tcagtttaca cgcagactct acggaatatg cgaatgaagc
    57541 aactggaatc acgacatatt attactatgg acaagaggaa acattagcac agacaattgc
    57601 tgactccttc actgatctgc ctctggattc aagaggaatc tccactggga actatcaagt
    57661 tcttcgagaa aatcttcaac cttctatttt aatcgagatg ggttatatga ataatgatag
    57721 tgatttaaag gaattagtaa cagacagtta tcagcagcag attgctgcaa gtttgacaca
    57781 agcattgacc acttattttc agtaataaat aagcccagcc aaacaaaaat agctcctcat
    57841 atttttcgtt tggccgggct tattatcgca gatgcaagct tttgaacacc gtttaaggaa
    57901 gaggttgtga gcctgccgtt taactccgcg tcacaaggag caatttcaaa aaacagcttc
    57961 tcatgtttga tgactattgt gacttgtgac cgaggagttg gcatgagaac accgtttatt
    58021 cggaacaagg gactgtgaca tgacttttgt cacagttcca ttattttttt agcagcttca
    58081 aagctttttc tgtattggca aaatgaagtt tggcatattt ttcaagcata ggcatgccgc
    58141 ctttctccaa tagttttgcc gctacttggt cagatttcgt tccagctcct gatggaaggg
    58201 tgattccagc ttcagctgat gctttgtgta actcttccaa aaagctggca cgactgatga
    58261 tagaagcagc agcaacagct aaatgatatt gttctccttt agtaacgaag tacagttttt
    58321 cttgtaattg atttttttct aaacgcgcat attttttaaa atttgcttcc ggcgtaaact
    58381 gatcgatcaa aatcgcttct ggtttttctg gctcgatttt ttttagcagc aaatggatcg
    58441 cttgattgtg caaagcgact ttcatccgaa cggcattgta ttttggttgg atctcattgt
    58501 atttttctgg agataagaca agcagtttat aggggatggt tttttttaag atgtcagcaa
    58561 gctggatgat ttggctatct tttaactctt ttgaatctct aacaccaagt ttacgtaatt
    58621 ctgcaagctg atcacgtttc acataagcag cacatactgt tagcggacca aaatagctgc
    58681 catttccgac ctcatcacta cctaaaacgg ataattgact gatatttttt ggcaaagaag
    58741 aggctgtttt tgctggcttg gcttgtttat cctgtgcctc cccccattta tcagcttcta
    58801 ttgctgcatt cgtaccttga aacatcactt ttccggatgt ataagcggta atggtcgtcc
    58861 cgtctttttt tgcagcaaag ctagtataag gaatctgttt atttaacaaa taagagcgat
    58921 agtatgcttt catttgacta agttggtcgt ttgttgcttt gataatgacg ttgctcataa
    58981 aattctcctc gtttttatac ataaaactat accgcaactc acgacttttc gttttctaag
    59041 agattgcgag acatagcatt tttttaaagt ttatcatata atagttaagt atgtgaaaaa
    59101 tatttgtgga gaacggtgaa agaaccaact tcatggtaca ctaaataaaa ctttcatcaa
    59161 ataggaggaa atgattcgta tggcgcacga aaaaacacgc tacaaagcag tgattgccaa
    59221 ccaaacatat actattatcg gacgggaaac caagcatcat atggatatcg taacgaagct
    59281 gatcaatgaa cagttagcag aattgaaaca attatcacca caaatggata atgaacaagc
    59341 agcaatcttg atggctgtca atgcgctttc ggatcaattg aagaaacaag aaagaatctt
    59401 ggagctggaa gaagaaacag cagaattaaa gaaaaaaatg atcaaattta cagagcttga
    59461 aaatcgtgtg aaacgcattg aagcaatcga gaacgaagct cgggaagtat tgaaagaaaa
    59521 tggtcaagca gatcatacca ttaaaaatca tgtggaagca caacagattt taaacgagaa
    59581 acgaaaagga caaattaaac aaaaatcttc taattaagat ccttttatca aaataagaaa
    59641 aatttaaaaa agttagaaga gaaaggaacg tagcatgctg agtttgctga ttttattttt
    59701 attgctaatt gcgttttttt ctggagcacg tcgcgggttt gctttgcaaa tcatattcgc
    59761 gattggatat gtattgtcat ttattgctgc ccagcatttt tacaaaccat tagcaagtca
    59821 tttggaatta tacattccat acccagctgt caccccaaca tcaaagttag cattttttga
    59881 tcaggtattt gcttttcacc tagatgaagc tttttatgca ggaactgctt ttctgattat
    59941 tttgctaatt ggctggctgc ttacccgatt tgtgggggtt tttgtccatg gattgacgta
    60001 tgtgccgatc ttgagacagg tagactggat tgcaggaggc atcctgtcac taatcatggc
    60061 ttacgttact atatttttga ttttgcagtt acttgccttt gttccattag atgtggtcca
    60121 aaatcaattc ggcgagcata gtttcgctcg ttttatcgtt gagagaacgc catttcttac
    60181 caacaagatg tatgagcttt gggtaacgaa tattttgaat taaggaaaat agtgctggaa
    60241 aatatttcgt tttttgtaca gagtagttta tttaagaagg ctgcgtagcg tatgtccggc
    60301 acagctcttt tttcatagtg aaagataagg tgataaaatg aataaccgaa tccttgaaac
    60361 attggaattt gaaaaagtca aacagatggt cagacaattt gtagtgactg cacaaggaaa
    60421 agaagaactg gcagaattgg taccagtgag tgagaaacaa acgatcacaa actggcttca
    60481 agaaactgag gatggattga aagtgcaacg tctgcgaggc gggatcccta tacctaaact
    60541 tgaaaatatc cgtccccata tgaaacggat cgagatcgga gcagacttga atggagtgga
    60601 gcttgcacaa gtttccagag tattgtctac gacaagcgaa ttgaatcgtt tcattgatga
    60661 tctttctgac agtgaaatcg aatttgcacg tttgtatatg tgggcagatc agttagtcac
    60721 gatccctgtt ttgagccgcc gtttaaagga agcaatcgat gaagacggac gcgtgactga
    60781 tgacgcttct cctgagttaa agagcataag acagaacatt cggcgaagtg aacaagctgt
    60841 tcgtgaacag ttagatggga tcgtccgtgg gaaaaatgca aagtatttaa gtgatgcgat
    60901 catcaccatg cgaaatgacc gctacgttat cccagtcaaa caagaatacc gcggtgtatt
    60961 tggcggtgta gtccacgatc aaagtgcttc aggacagact ttatttattg aaccaaaaca
    61021 agtggtggat ttgaataatc gtttgcgtca ataccaaatc gctgaacgaa atgagattca
    61081 acgtatttta agtgaacttt ctgctgaact tgttccccat cgtcaagaaa tcatccacaa
    61141 tgcttatgtg attggtaaaa tggatctgat gaatgcaaaa gcacgatttg gtaaagaagt
    61201 aaaagccatc gtgccgggaa tcagtgaaga caatcatgtc gtcttgaaac aagcaagaca
    61261 tccactgatc gatcaggaaa aagtagtttc taatgacatc acaatcggaa aagactatca
    61321 agccatcgtc attacaggac ctaacacagg tgggaaaacg atcacgttga agactttagg
    61381 tctgttacaa ctgatggggc aagcaggatt accgattcct gcaggtgaag aaagtcaaat
    61441 cggtattttt gaggaagtat ttgcggatat aggagacgaa cagtcgattg agcaaagtct
    61501 atcgaccttt tcttctcata tgacgaacac tgtagatatt ttatcaaaag tcaatgaaaa
    61561 aagtctggta ttatttgacg agctcggtgc aggaacagat ccgcaagaag gtgctgctct
    61621 agcaatcgca atcttagatg atcttggtaa aaagtctgct tatgtgatgg caacaacgca
    61681 ttatcctgaa ttgaaagttt atggatacaa tcgggcaaat acgattaatg ccagcatgga
    61741 gttcgatgtg gatacactaa gtccaacgta tcgtttgctg attggcgttc ctggacgaag
    61801 caatgcgttt gaaatctcta gccgattagg tcttgataca gaagttattg atgaagcgaa
    61861 gcagttgatg aatgatgaga gccaagattt aaacgaaatg atcacagatt tagagaatcg
    61921 ccggaaaatg gcagagaccg aatatctgga aatgcgtcat tttgtttctg aggcacaaga
    61981 acttcacgat gatttgaaag aagcttacag ctatttcttt gaagaacgtg aaaaagaaat
    62041 ggaaaaagca aagaaaaaag caaacgaagt cgtgtcagag gcggaagaaa aagcagaaaa
    62101 aatcattgct gatattcgta aaatgcaaca gcagattggg caaggaaatg tgaaagagca
    62161 tcagttgatc gatgcaaaga cccaattagc aaatctacat caagaagaaa ctttgaagaa
    62221 aaataaagta ttgaagaagg cgaaagaaca aaaaacgttg aaaccgggag acgaagtgtt
    62281 ggttacgact tacggccaaa gagggacgct tttacgtaaa aacgggaatc agtggcaagt
    62341 agaaatcggt atattaaaaa tgaatgtgtc cgaagacgag ctgacgcctg ttgctcctca
    62401 aaaagagccg acacaacgag ttatccatgc tgtacgatct gaatctagta gtcacgtgcc
    62461 gaatcaattg gaccttcgag gaaaacgata cgaagaagcg ctaagtgagg tagatcaata
    62521 tttggattct gccattctag ctggttatcc tcaagtgact attgtccacg gaaaaggaac
    62581 aggcgcactt cgcaagggaa ttactgatta tcttaaaaac catcggagcg tcaaaagctt
    62641 tgagtttgca ccggcaaacc aaggcggaaa tggtgcgaca attgttaaat ttaagtaaag
    62701 cttactaaag gtaagcagat ggttcgctat ccaagtatag aaatgctata ctaatcatag
    62761 attttaaaaa tggaggtctt tgatatgtca caagtaatta cagataagac atttaatgaa
    62821 gaaacagata aaggacttgt attgattgat ttttgggcaa cttggtgtgg tccatgtcgt
    62881 atgcaagcac cgattttgga tcagttggaa caagaatatg atgaagaaga attcagaatt
    62941 gctaaaatgg atgtggatga aaatccagaa actcctcaac aattcggtat catgagcatt
    63001 ccaacattaa tgttgaaaaa agatggtcaa gtagtagaaa aagctgttgg tgttcattca
    63061 aaagaacaac tacgtcaaat gatcgatcaa tatttataaa aacttacagc aaaaataagc
    63121 tgagggtggg actgaatcca gttccgtcct cggttttttt gcggttgagt taaggttatt
    63181 caaattaata ttttttgagt ataattacgt tgtcaggctg gattgttttt ttgacagaca
    63241 tgctataata actttaattg aatatgaagg ggagtaccag atgaacgaac gaatcaaaaa
    63301 caaattagct ttacttcctg atcagcccgg ctgttacttg atgaaagata aaaatggaac
    63361 gatcatttat gtcggcaaag ccaaaatatt aaaaaatcgt gtccgctcat attttactgg
    63421 cagccataat acgaaaacgg aacggcttgt tagtgaaatc gaagactttg aatacatcgt
    63481 tacagaatcg aatatcgaag cattgctctt agagatcaat ctgataaaga aaaatgatcc
    63541 taaatacaac attatgttaa aggatgataa aacctatcct ttccttaaga taacgaatga
    63601 aaaatatccc cgtttggtga ttactcgtaa agtactaaaa gacaaagcac tgtattttgg
    63661 accatatccc gatgtcggtg cggcgaatga gacaaagaag atcctcgatc gattatttcc
    63721 tctgagaaaa tgcaaaccta gtcagacgaa ggagccttgt ctttactatc atttgggaca
    63781 atgtctgtgt ccttattatt tcgacgtaga tccgaaagtc tatacgaaaa tcgttgatga
    63841 agtgaaaaag tttttaaacg gaggacacga aaaaatcgag tcagagatcc atcagaaaat
    63901 ggaaaaagct gctgaaaaca tggagtttga aaaagctgca gaataccgag accagatccg
    63961 tgccattgag acaatcatga ctcgccaaaa aatgacaaat actgatttac tggatcgaga
    64021 tgtatttggt tatgcgattg acaaaggatg gatgtgtgtc caagtgtttt tcgtaagaca
    64081 aggaaagcta attgaacgag atgtttcaat gtttcctttc tataacgaag cagaagaaga
    64141 tttcttgact tacctcggtc agttttatca ggaaaatgag catttcattc ctaaagaagt
    64201 cttgattcct gatacgatcg acaagcccag tgtagaagct ttgttagcta cgaaagtgct
    64261 gcaaccaaaa cgaggagaaa agaaaaaatt agttgaattg gcgaataaga atgcctcagt
    64321 tgctttgaat gaacggtttg atctgattgc cagaaaacag gaacggacga tcggagcagt
    64381 tgaacgttta ggaaacgcga tgaatatccc gaccccaata cgtatcgagt cttttgataa
    64441 ctctaatatc atggggacga atcctgtggc tgcgatggtc gtattcattg atggaaaacc
    64501 ggcaagaaaa gaatatcgga aatataaaat aaaaacagtc aacggaccgg atgattatgc
    64561 atcaatgaga gaagtcatct atcgcagata ttcacgagtg attcgcgaag ggttgccttt
    64621 acctgatttg atcttgatcg atggaggaaa aggacaagta gatgtggcaa aagatgtctt
    64681 agaaaatcaa ttaggaatcg atattcctat tgctggcatg gcaaaaaacg ataaacataa
    64741 aacaaatgag ttgctattcg gtatagattt ggctgtagta ccgcttgagc gaaattcacc
    64801 agagtttttc ttactccagc gaatccaaga tgaagtccat cgattcgcaa tcactttcca
    64861 tcggcagcta cgcagtaaaa acagttttgc ttcccgatta gatgaaattg aagggttagg
    64921 accaaaacga aaaaaaatgc tgcttaaaga gttcaaatcg ttgaaaaata tcacagcagc
    64981 cacgacagaa gaattacaag aaatcggact gccgaaaaat gtcgcacaaa acgtatttga
    65041 taaattacat caggaatgag gaaagggcac tttacaaaga aagtaaagtg tcctatcatt
    65101 ttatgtacaa caaaaagagc gtttacgttt tgttggtaaa taataaatcg cttacgtctg
    65161 gtgtctaagg atatatgtga tttcttgaag aaggagtgaa gaaatgttag aagtcaagga
    65221 tcttgttaaa acttttggga actacacagc tgtcgatcat gtctctttcc aaatccccga
    65281 tggaaaaatc atggggctaa ttggccaaaa cggggctggg aagacaacga cttttcgttt
    65341 gatcttggat tttttgacac aagaccaagg agaagtgtta tggaatggcc atcatcttgg
    65401 ggagaaagat tatgatgtca tcggttatct tccggaggaa cggggacttt atccgaaagt
    65461 aacgattcaa gaccaactgc tttattttgc agaacttaga gggaaatcaa gaaaagagat
    65521 tgaaccaaaa atcgattttt ggatggaaaa atttcaggta aaagggaaaa agacggataa
    65581 agtaaaatct ttgtctaaag gaaatcagca aaaagtccag ctgatcgcca cgttaatcca
    65641 tgaacctaaa ttgatcattt tggatgagcc attcagcggg ttagatccgg taaatgctga
    65701 attgctaaaa gatggaatat tggaattgaa aaaacatggt tcatgtgtca ttttttctag
    65761 ccacaatatg gataatgtag aaaaaatctg cgatcatttg atcatgttgc gaaacggaaa
    65821 aatggttttg aatggaaaag tacatgagat tcgtgaatca tttggccgta cgaagttatt
    65881 cttggaatct ggtttaagcc aacaggaagt agaagaaatc gaaggcgtga aaaaagtgat
    65941 ccttcatgaa gacaatacgt tagagattac cttagaagat cctgaagctg ggaaagaaat
    66001 ctttactcgt gcgactcagt tcggctacat tcctatgttt aaccagcaac cgccaacttt
    66061 ggaagagatt ttcaaattga aagcaggtga aatcgatgcg taagttttgg attattacca
    66121 aagatgtcta tttaaaaaat gttaagtcga tttctttctt gatcatgata ttagtccctt
    66181 ttatcatgct gggtatcatt tatgtagcag gaaactttgc tcaacaaaat agtgatgtca
    66241 ataaaatcgg cgtattggct gataatgagc aaatcagtca gcaaatgagc caagtcaaaa
    66301 cagatgattt tgagttcaaa gcagttgatt ctgaagaaaa agcacaaaaa gagctttcgg
    66361 aagaaaaaat cgatgcgtat ttagtagtct caactgagaa tgataagata aatgggatgc
    66421 tttatagcga aaattcatta ggacaaagta cacaactact gatacaacaa caactgactg
    66481 gcttgcaatc gatgcttcga gcaagtcaat taggcatttc accagaagaa gtagctagct
    66541 tgagccaaca agcaagtttg actcgacaaa aagtcaattt tgattcaaaa ggaaaaatga
    66601 cagttggaga agataactcg acagtccaat atgtcgtaag ttatgtagca acgattgtct
    66661 tgttcattat tattttgacg tatgcgcaga tcattgcaca agagatcgct tctgaaaaag
    66721 gcacgcggat catggaagtg atcctgtcca gtacgactgc acaaaagcat ttttacggaa
    66781 aactaacagg tgttttactt gttgcattaa cgcaaatggc attatacggt attatttttg
    66841 gtataggata cagtcaattc aaagatatgg aaatggtcaa aaatatatta gacggtatct
    66901 cattggataa cttgattgga ccattcttgt ggtattctct tctattcatg atctttggca
    66961 ttttgatttt ttctgtttta gcagctttat gtggctcttt ggtcaacaaa gcagaagata
    67021 cagcaaaagc aattttgcca gtgacttatc tatctctagg cggatatatg cttggattga
    67081 tactaggagc ttcagatcca aacaatatcg ttattcggat cacttcgtat attccattct
    67141 tatcttcata tattatgccg gttcgcttag caaatgagac agtcggtatg ggtggagcat
    67201 tgatttcctt gttggtactt gtagccgtaa cattcttatt gatgatcttg tctgcaaaca
    67261 tgtacaaatc gaatgtactc gtgtatagcg aaggcggatt atggagttca ttgaaacaat
    67321 cgatttcaat tatgagaaat gaacgaaaaa aagcataaaa tatagaaaaa tatagaagga
    67381 agctggacat ttattgttcc cagcttcttt tttgtataga cctatttcta tttttttatt
    67441 atattggata tatattcatt gaaaatagag cataacaact ttataatgtt gagtatacca
    67501 atttttggag gcgttttaat ggaccgctat ttagatttac tttcagagaa gttccctaca
    67561 acggaagatg tcatcacgga aatcatcaat ctcgaagcaa ttttgcagct tccaaaagga
    67621 acagagttat ttttgagcga tatacatggc gaatttcctg cttttgatca tattctgcgt
    67681 atcggttcag gaaatcttaa agaaaagatc aaagaccttt tctctgaaca aatgacggaa
    67741 acggagatca gccaattcac tatttttacg gcttatccag aatatgtgtt gacgactgat
    67801 tggtacaaaa aacaagataa atcccagctg atccatcgtt tgatcgatct tttacggttt
    67861 acgacagtca aatacactcg atcaaaagtt cgaaaaggat tgccgaaaga atatagctat
    67921 atcattgagg aactcttgta tatcgatgat cgtatcaacg ggaaaaaaga ctatgtaaaa
    67981 aaaatcattg aacaacttgt cttgatgaag gaagaagaaa aatttttaac aaaacttgcg
    68041 cagacgatcc aaaaatctgt catcgatcat ttgcatatcg tgggtgatat ttttgatcga
    68101 ggaactcaag cagccaaagt aatggatcga atcatggatt tttcctctgt agatatccag
    68161 tgggggaatc atgatatttt gtggattggt gcgtattgcg gctctgaggc atgtttattg
    68221 acgcttttac ggattgccgc acgctacaac tatttatttg aattagagaa agaatatgga
    68281 ttaaatttac gtccattatt ttcttttgcc catcaaacct atcagaagaa tccagtattt
    68341 acccctaaaa acaggaaaga tctatctgaa agagagcaag aagaattaga aaagatccat
    68401 caagcacttt ctatcctcca attcaaatca gaacatcagt tgttgaatcg acgacctgaa
    68461 tttaaaatgg acgatcgtaa attgttggaa aaaatcaact atgaggaatc aacgatcgtt
    68521 ttagaaggtc agctctatga gttgaaaggg acttgttttc aaacgatcca gccagatgat
    68581 cctaaaaaat tcttggaaga ggaacaaaaa gtgatcgata gtttgatgta ttcattccag
    68641 cactcgttaa gaatgcaaaa acacatgacg tttttgatcg aaaaaggggg aatgtatctc
    68701 acgaacaatc agcatgtact gttccatggc tgtatacctg tagatgaaaa ggggcagctc
    68761 ttagcatttg aattagacca atcttatcgc ggaaaagaac tgctgggatt ttttgaaaaa
    68821 cagataactg aaagcgcaaa agatttgact gcaaatgaag atttggcgac cgatttgatt
    68881 tggtatgcgt ggagcgggcc attttcgcct ttattcggca agagtaaaat ggcaactttt
    68941 gagcgctatt ttctcacaga gcctcatacg cacgtcgaaa aaagcaatcc ctattatcac
    69001 ttgcgagatg aagagtggtt cagtgaaaaa attttggcag aattcgatgc aaaagaagaa
    69061 ggttcagcaa tcatcaatgg acacacgcca gtaaaagtaa aaaaaggaga gtcaccgatc
    69121 aaagcaaacg gaaaagcatt tgttattgac ggaggtctat ccaaagctta tcaaaaaaca
    69181 accgggattg ctggctactc attactatgc aattcttacg gtttccaaat cgtgacacat
    69241 tatccgttct tgcctattga acaacaattt gcaaaaaaat ctgatcaaac gaatgtaaaa
    69301 aaagtgatcg agcagcagct cccacgcaaa cttaatcgga atacgacaaa aggaatggaa
    69361 ttacagcaac agattactca actccaaagg ctgttggatt atcgaaagga cgattgagaa
    69421 aaatgctagc caacattgct caatagacta aaaagcgact gcaacaaaag gcgtgtcgca
    69481 gtctccttcg gaattagctc aaaaaacggt aaaatattag aagctatttt tctgtttatt
    69541 tctctaatac tcaggtcagg gcgctgattt cacgacctct tccttaaacg gtgttctcct
    69601 gccaactcct cggtcacaag tcacaatatc caacaaacat gagaagctgt tttttgaaat
    69661 tgctccttgt gactcagagt tgaacggcag gctcacgacc taatcagaaa aacgattaaa
    69721 attcattcac aaagaaatcg aataaacgct gttcagatga atctacacga tgagaaagtt
    69781 ccggatgcca ttggacacca aggattttgt gcatattatc tttactttgg actgcttcaa
    69841 tgagtccatc gttggaaaag gcgatggctt ttaacaaagg agaaagatct ttgactgcct
    69901 gatgatgata ggaattcaca aagtatgaat cagggagaag gtcacttaat aaactgtccg
    69961 aaacgatttt gacttcgtga gttgcaaact gcggggcagt gggctgttgt tcgtgtttta
    70021 cggaccattt tggatataat gaaagatctt gataaagtgt tccctccaac acgacattca
    70081 atagttgaag tcctcggcag actgcaaaaa tcggttttct ttgtttcaat gcttccaaga
    70141 tcaatgcctg ttcgaattgg tctcgttgaa tatttgtttc cgtcagtttt ggatgagggt
    70201 cttccatgta aagttgcgga ctaacatcct gaccgcctgc aagaatgagt ttgtcgattt
    70261 tctcaattag ttgaggcgct gaatctggag acatgactgg cagaataaga ggtaatcctt
    70321 gagcatctaa aactgcatcc acaaatccct gcggtgtata gcttacttga tttccttgga
    70381 aagtatctgt cgctcgaatc agttgattcc cggcaatgcc gatgattggt ttcattttta
    70441 ttccccctaa agtagactaa ttgtaacaag gatttaaaaa aatttaaact atgtaagact
    70501 tgcccctata cttatctgtt cttgctgtgt tactatctgt aaagagaatt ttcgtgtgaa
    70561 attcatgacg atagttgaaa atattgctta atttgttata ataaaaagta agcagaaata
    70621 aaaaggttgg gcgtaagctt caaggatcta gttcttcaag gggtgagaag gacattttat
    70681 tgaaggggcc tgcctatact aagttatctt tagaggtaca tactttcaat gaaaaaagaa
    70741 agcatgtacc tcttttttaa atcgaaagga agtgaagcaa gtgttagaag ctttggaaca
    70801 aatccgaaaa gcagaagaag aaaatgagaa gcgtgctcga accctacggc agcagttgaa
    70861 gacctatgca gaagaaaaag agcaagaatt ggagataatc caaacgaaca gtcggcaaca
    70921 gctgaaacag ttggtagaag aaaaagaaca attcgaaaag caagaattag aaaaagaaaa
    70981 aatgaaattg aaagcagaag cagacaaggt gcaagcaact ttgaaagacc aatatcaaaa
    71041 gcatcagagt caagcaatcg gtgcaatcat tgaaagggtg aaagaaactt atggccgtca
    71101 ctaagatgga aaaagtgacc ctcatttcag ataaaagaaa tcaggagagg attttacaag
    71161 cagtacaagg aatccaaaat gttgaaatcc gggatctgta tcaaaataga acaaacaacc
    71221 agtgggtaga aaaatatttt ccagatacca cgattattga taaagaagca aaattaagcg
    71281 ctttaggcaa tcggctgaaa gacatccaag aagctatcca attcatacaa caccacggcg
    71341 atagccgtca aaagaaactc catttgaaac gtcaagaact ttccttacaa gacttggaag
    71401 caaattattc cgaagaaaat ttcatgaata aattagaaga ggtccttgat ttaaaagaaa
    71461 agtgggaaca gctaactgaa aaacgtgatc gtttagaaga agaggaagaa tggcttcttc
    71521 attggcaaca gctggatatt gctccaagta tgtatgcaag taagacgacc atttttgaga
    71581 tggggactgt gagtgcagca aattttgaaa gtttcaagga agaactaagt aagcttgatg
    71641 acgtttatat ggaagaaata gattatacgc caaaacaagt ttatctttcg tatgttgctt
    71701 taaaaaaatc agttgctgct atagaagaaa ttgctgggaa atacgggttc aataaagaaa
    71761 cgtatcctta tgaacaaaat cctaaagaaa aattgcaaga aaccaaacag caattatcca
    71821 ttgttcacga gcagcaaaaa aagataacga cagcgttagg tcagtgcagc ggctatatcc
    71881 aagaatttga atgggtagaa gaagtcacac ttgccgttgc agaacgggaa aaagtaaaag
    71941 aacggtttat ccatgccact tatctgatcg ttttgcaagg ttgggtagat gcagaagaaa
    72001 aacagaattt gatgcatgtg ttaaacgaaa ctgtatcaga agaagatata tacgttagtt
    72061 tcgaaacacc aaactcagaa gagattcagc aggaagtccc tactaaattg aaaaaccatc
    72121 cgcttatcga accttttgaa ttgctgactg aaatgtacag tctgccaaaa tatgaagaag
    72181 tagatccaac gccttggatg acaccatttt atcttgtctt cttcgggatg atggtcgcag
    72241 atgttggtta cggattgctg atgctcattg ggacaatact agctcaaaaa ctatttgttt
    72301 taccccgcgg gatgaaacgt ttcgtaaaat tctttgagat tctctcggta ccatcgatca
    72361 tctggggatt gatctacagt tcatttttcg gacaggcatt accaaaagaa ctatttggta
    72421 tccgcttgcc tttcccaatc ctatctacga cggatgacgt caatacgatt ttgattttat
    72481 ccgtgatttt cggtctgata cagatcttgg ttggattatt cgtggcagca aaggaaaata
    72541 tcaggaggaa agattacttg agtgctgtca gtgatggttt tgcctggcaa gggatcctga
    72601 ttgggatcgt tattgcattg attggtgtca tgttgataaa aaatacagca tttgtttatc
    72661 ttggcgcggg gctatcgatc attgctgctt tatgtatctt aatcgtgccg attatccaat
    72721 cgccgtctaa agtcaagggt gctgccaaag gagcgtataa tctttacgga ttgactggtt
    72781 atatcggtga tttagtcagt tatacacgtt tgatggcact aggtatttca ggcggaagta
    72841 ttggcgcggc attcaatatg ctagttgctt tcatgccgcc agccgctcga ttcagtgtag
    72901 ggatcctttt gatcatcgct ttacacgcac tgaatatgtt tttgacactg ttaagtgcct
    72961 atgtccatgg tgcacgattg cagtatgtcg aattttttgg aaaattttat acaggaggcg
    73021 gacgtgcctt tgacccgctg aaaacggcgg aaaaatacgt caacatcaat cataagaaaa
    73081 aaaacaataa ataattggag gatttttata caatgatgga ttacttaatt agtcaaaatg
    73141 gtggaatggt atttgcagta ttagcgatgg caacagcgac gattttttca gggattggtt
    73201 cagctaaagg tgttggaatg acaggtgagg cagcagcagc gttaacaaca agtcaacccg
    73261 aaaaattcgg acaggctttg attctgcaat tgcttccagg tacgcaaggg ttgtatggat
    73321 tcgttatcgc ctttttgatt tttatcaact taggaaatga tatgtcagtt gtacaaggat
    73381 tgaactttct aggcgcttct ctgccgattg cttttacagg tttgttttca ggtatcgccc
    73441 aagggaaagt tgcagcagca ggtatccaaa ttttagcgaa aaaacctgaa catgctacaa
    73501 aaggaatcat ttttgctgcg atggttgaaa catatgcgat tttaggtttc gttatttcct
    73561 tcctattagt attgaatgcc taagcataaa ggaggaaaag cagatgaacg ccattgaaaa
    73621 aatcatctct cagatgaatg aagcagcaga gcaagaaaga gcggcgttag agcaagaaga
    73681 gcgaatgaag atcgatcaaa actttgaaca aaaacgtacg caaatcgaaa cagaacatca
    73741 aaaacaaaaa gaaaaacaaa tcgaattact tgaaaaaaaa taccgtcagc ttaggaatcg
    73801 ccaacaagta gaagtacgac aagaaaattt gaatgcgaag caggaatttt tacgacgatt
    73861 gtttgcagat gcaatagctg aaatggagaa ttgggatgaa tctgaacaaa tccagtttat
    73921 caaaaattca ttgtattcat tacctttgac aggcaaagta acattcattg ctggagaaaa
    73981 atcagcagct tatctttctc agacattgct ggatgaatgg aacaatgaac ttccctttat
    74041 gatggtttta agtgatgaaa ctgttgctga tcaagcgggt tttctgataa acgatcaagg
    74101 agttcagtat aattttcttt tcagcagcct tgtacaagat atccaaggaa cgatgagttt
    74161 tgagattgcc aatcaattat tcgaataagg agggatcagt gtatggaata ccacgaacta
    74221 aatcccttga ttcgcggaag agagcttgaa cttttgtcca atgagacatt tgaacggatg
    74281 attcaaacaa attctgtcga agcacttggt gaaatattga aatccacgat ttacagtcca
    74341 tatatttatg acggatatga atatgacttc gaacagaatc ttttaaagga gcagagccgt
    74401 ctatttcgct ggttaaagga atcagcaccg gagcctgaaa tcgtttggat ctatacgatg
    74461 cgctatactt tccataatct gaaggttttg acaaaagccg agatgacaaa tcaaaatctg
    74521 gaccatttgt atatcgacga tggattttat tcattagaaa ccttgaagga tgccattcat
    74581 acgcaagttt caaatgaact ccctgaaagc attatggaca gtatacgaga agtacgtgat
    74641 tattttgaag agtctaccat tcttcaggga attgacgtga tttatgatcg acagtttttg
    74701 acagagcagc gacggcttgc cgataagcta ggatatcaag aattgctgac agaagtcatt
    74761 gcttttattg acttgaccaa tatcacaacg atggctcgag gaatattgca gaaaagaaca
    74821 tatgggttca tgacgacggt actttccagc tcgggaagta tcgaaaaaga agtatttttg
    74881 aactttgtag ataaagatat ggaagattac acgaattttc tattagagac agattatgct
    74941 gattttctgc gccctgtcat ccgtgaggga aatcttgatc tcgtaaagct tgaacagttg
    75001 aaagatgatt atctaagttc attgtatcaa gaagcacaaa cccaggcttt cggaccactg
    75061 ccactactag cctttttgaa cgcaaaagag gtagaaagca aaaaccttcg tttactggtt
    75121 atcggcaaaa gaagccattt cgaaccagaa acaatcagaa agcgggtgag acaagtctat
    75181 gacgcataag atcggtgtag ttggcgacaa agattctgtt ttgccattca aattgtttgg
    75241 ctttgatgtt cgttatggta caaccaagca aaccgttcgt caggcaattg aagaaatggc
    75301 aaagaatgag tatggcgtga tttatgtcac agagcaatgt gcagcattga gcccagaaac
    75361 gatcgaacgt tacaaggaac aaatgatacc tgctatcgta ttgattccca atcatcaagg
    75421 atcattaggg atagggctgg aagaaattca aaaaaacgta gaaaaagcag taggtcaaaa
    75481 tatcttatag tatgaaaagg agatagaaat tttgcaaatt ggaaaaatca taaaagtctc
    75541 cggacctctt gtaatggctg agaacatgtc tgatgccagt atccaagaca tgtgtctagt
    75601 gggagatcta ggagttatcg gagaaattat cgagatgcgt ggcgatgtgg cgtctattca
    75661 agtatatgaa gagacttctg gaattggtcc aggcgaaccg gttcgctcta ctggtgaagc
    75721 tttatctgtt gaattaggac cagggatcat ttcacaaatg tttgacggaa tccaacggcc
    75781 attagatacc tttatggaaa tcacacaaag taatttctta gggcgcggag ttcaattgcc
    75841 cgcattggac catgagaaaa aatggtggtt cgaaccaaca gtagaagccg gagaaacggt
    75901 gagtgctgga gatgttatcg ggatcgtaga agaaacaaaa gttataaaac ataaaatcat
    75961 ggtgccaaat gggataaaag gtacgatcaa aacaatcgaa aaaggttcat tcactattga
    76021 tgaaacagta tgtgtcattg aaaccgaaaa tggtgacaaa aatttgacga tgcttcaaaa
    76081 atggccagta agacgtagtc ggccaatcaa agaaaaatta aacccggatg cacccatgat
    76141 cactggacag cgagtgattg atacattctt cccagtgaca aaaggaggag cagcagctgt
    76201 acctggtcct tttggtgcag ggaaaacagt cgttcagcat caaattgcaa aatgggccga
    76261 tgtggacatg gttgtctatg tgggatgtgg cgagcgtgga aatgagatga cggatgtttt
    76321 aaatgaattc cctgaattga ttgaccctaa tacaggagaa tcgttgatgg aacgtacggt
    76381 attgattgct aatacatcaa acatgccagt agcagctcga gaagcttcta tctatacggg
    76441 aatcacaatt gcggaatatt tccgtgacat gggttatgac gttgctatca tggcagactc
    76501 cacttcacga tgggcagaag cacttcgtga gatgagcgga cgtttggaag aaatgcctgg
    76561 tgatgaaggt tatccagctt atcttggttc acggcttgcg gaatactatg aacgatctgg
    76621 aagagtcatt gcattaggat cagaaggtcg cgaaggaagt ataaccgcaa tcagtgctgt
    76681 atcgccgtct ggaggggata tttcggaacc agtcacacaa aatacattgc gggtcgtaaa
    76741 agtattctgg ggtcttgatt ccagtttagc ccaaaaaaga cattttcctt cgatcgattg
    76801 gatacaaagc tattctcttt attcaacaga agtagggaag tatatggatc atatccttca
    76861 agctgactgg gcatccatgg tcaccgaggg catgcgtatt ttgcaggaag aacagcagct
    76921 gaatgaaatc gtgcgtttgg tagggattga ttccctttca gataatgacc gtctgacatt
    76981 agaagtggca aaatccattc gtgaagatta tttgcagcaa aatgcttttg atgatgtcga
    77041 tacattcact tcaagagaga aacaattcaa aatgttgaag atgatcttga cctttggtga
    77101 agaaggacgc cgtgcgttgt cgttaggtgc ttatttaagt gagatcatgg acggtaccgt
    77161 atcgattcgt gaaaggatcg gacgaagcaa atatatcccg gaaacagaat tagaaaaact
    77221 agatcaaatt attggtgaaa tcaagcaaac gatgcaaacg atcgtttcag aaggaggcat
    77281 gagcaatgat taaagaatat cgtacgatcg gtgaagtcgt cggtccattg atggcggttg
    77341 aaaaagttgc tggtgtcaaa tatgaagaat taatcgaagt ccgtatgcaa aatggcgaga
    77401 ttcgtcgtgg acaagtattg gaagtccaag aagataaagc aatggtccaa atattcgaag
    77461 gaacaagtgg tatcaattta cgtgactctt ctgtacgatt tttaggccat cctttagaac
    77521 taggtgtatc ggaagacatg atcggtcgag tattcgatgg tttgggacga ccgaaagata
    77581 acggaccaga gatcctgcct gaaaagcatt tggatattaa cggagaagta atcaatccag
    77641 tagctcggga ttatccagat gagtttatcc aaacaggtat ctctgcaatc gatcatttga
    77701 atacattagt tcgtgggcaa aaattaccag tattttctgg ctctggtctt cctcataaag
    77761 aattagctgc tcagatcgcg cgacaagcaa cggtactcga ttcatcagat gatttcgccg
    77821 tagtctttgc tgctattgga atcacttttg aagaagcaga atttttcatg gaagattttc
    77881 gtcaaacggg cgcaatcgac cgttctgtca tgtttatgaa tttagcaaac gaccctgcaa
    77941 tcgagcgtat cgctactcct cgtatggctt tgactgctgc agaatatctt gcttatgaaa
    78001 agggaatgca tgttttggtt atcatgacag acatgaccaa ctatgcagag gcattgcgag
    78061 agatttctgc agcacggcga gaagttccag gaagaagagg atatcctggg tatctttaca
    78121 cgaacttagc tactttattc gaacgagcag gaagaatccg cggactaaaa ggatcggtta
    78181 ctcaaattcc gattctaaca atgccagaag acgataaaac tcatccaatc cctgacttga
    78241 ctggttatat tacagaagga cagatcatct tgactagaga gctttacaag agtgggattc
    78301 agccaccaat tgatgtactc ccgtctcttt cgcggttaaa agataaggga actggacccg
    78361 gaaagacaag agaagaccat gcagctacga tgaatcagct ttttgcagcc tatgcacaag
    78421 gaaaacaggc aaaagaattg gccgtagttt taggtgaatc tgctttatct gatgtagaca
    78481 agatctatgc gaagtttgct gagcggtttg aaaaagaata tgtcaatcaa ggattctaca
    78541 cgaaccgttc gattactgaa acacttgatc tagggtggga actgctatcg atgttgccaa
    78601 gaaccgaatt aaaacgaatc aaagacgaca tgctggacaa atatctgcca gaagggaagt
    78661 gagttctgat ggcacgattg aatgtgaatc cgacccgcat ggaattgact cgattgaaaa
    78721 aacagttgac aactgccaca agagggcata aattattaaa agataagcaa gatgaactga
    78781 tgcgtcaatt catcctgttg attcgaaaga acaaccagct gcgtcaagaa atggaagagt
    78841 ctatgacaga agcaatgtct gattttgtat tggcaaatgc ttcgatcacg gagcctttca
    78901 tcgaagaatt atttgttttg ccggcggaaa acgttgattt gtctatcgta gacaaaaata
    78961 tcatgagtgt aaaagtacct gtgatgaatt ttgaatatga tgaacagctg acagacacac
    79021 ctttggaata cgggtatttg aattccagtg ccgaactgga tcggtcaatc gatcggttta
    79081 ctaccctgct tccaaaactt ttggaactga cagaaatcga aaaaacttgt caactgatgg
    79141 cgagtgaaat cgaaaagaca cgtcggcgag tcaatgcatt agaatatatg acgatccctc
    79201 aattagaaga aacgatctat tatattcgta tgaagctgga agaaaacgag cgcgcagaag
    79261 taacaaggtt gatcaaagta aaaaatatgg gtaccactga ctaagtggta tcctttttta
    79321 aaagaggaaa acgatgatta aacaaagcaa acaaataaag aaacgcttgc cggctgttca
    79381 gcttctcgca ttaggatttt ttctcctgat tttagttggc ggcggcctac ttaccctacc
    79441 attttttagt aatagtgggc atgggacaaa ttttatcgat gcgcttttca ctgcaacttc
    79501 tgctgtctgt gtgacgggat tgacaacatt gaatacagca gagcattgga acagtgctgg
    79561 tcaatttttg atcatgcttt tgattgagat cggcggtctt ggttttatga tggttccgat
    79621 tctatgcttt gcattgataa agaagaaagt cagtctcagc acacgtatta tattaaaaga
    79681 agcgctgaat ctagaagaag tatcaggtgt gatgaagctc atgctttaca tcctgaaatt
    79741 ggcctttgtg atccaactga ttggtacggt tgctttatct tttgtattcg tgcctgaatt
    79801 tggctggttg aaaggtatct ggtacagttt gttccatgca atctctagtt tttgtaatgc
    79861 agggtttgat ttgttaggag acagtttagc caatcaccag caaaatgttt atttgatcat
    79921 ggtggtatct gctttgatca tttctggtgg gttaggcttc atcgtatggc gtgatttact
    79981 ggaatatcat cagaaaaaga agataacgat tcattcaaaa atcgcattaa ccgttacagg
    80041 taccctttta ttaggcggat tcgttgtgtt ctttttcaca gagcgcaatg gggaaacgct
    80101 agtggaaggg aatatgtttc aacgattggc aaacaccttt tttatgagtg tgacacctag
    80161 aacggctgga tattattcag ttgattacct ccatatgagc catgcaggtc tgattttaac
    80221 gatgtttttg atgtacatcg gtggaacatc tgggtcgacg gccggcggat tgaaaacaac
    80281 tacgttaggt gtgttgctga tccagatgcg ttcgatgctt aaaggacgta cgagagcgga
    80341 agcatttggc cgtaccatcc gacaaggcgc agtgttgcgg gcacttactt tattttttgt
    80401 tacgttgacg ttgtgtgtag tcgccatcat gattttatcg gtgactgaaa cgatacctaa
    80461 aacttctggc atcgaatata ttgcttttga ggtcttctct gcgtttggta cagtaggtct
    80521 tacgatggga ttgacgccag acttgactgc aatagggaaa ttgatcatta tagcgcttat
    80581 gtacattgga cgagttggtg tattgactgt ggtcttctct ctgatgacaa aagcacaaag
    80641 aacacaatca aaatacaaat atccagaaga aagtgtcatg attggataat ttcatcttct
    80701 gacagaaacc tagtgattta gtaaaataag aaaataaaat aatttttctt gcttcttgga
    80761 tactttaagt gcaaaatgtt cgtttatttt ttgaggcact atccgttgtt gaacctcggg
    80821 tagtgcctct ttcttattga aaggaatcaa taagatttga ttcctttatt tatcaatagg
    80881 ttataattca tattttttta ttttttcttt tacgatactt agtccagaag ctaaaatttc
    80941 aaggttatta gaggataggg aaattcgaac gaatgcatct ggttgcgcac gtgtagtaaa
    81001 gcgtctggaa tgataaagtc ggataccgtt agcaagaaag tcattctcaa ttatcttagg
    81061 atcaatctca ggatcaactg gaagaattcg atagtaaggg acacgattcg ttggtttttc
    81121 tactttgaaa agagaatcaa aaagctgatt ggctcttttc gtaagactta atttagtttc
    81181 taagatccta tttgcttcat ttgaatggag gatttgagtg atgacttcca catctaatcc
    81241 agaagttttc acatttatat taaaaattgc ttgttctatc ttgttttgga catgtactgg
    81301 aactacaaga taagcaactc gcaatccaga acaaataaat tttgtcattc cagctaagta
    81361 gattgtttgg ttaggtaata atttttggaa aggaggaatg atcgtatgtt gatagtaagt
    81421 tgttaaaaat gaatggatat catcttcaat aacccataga ccttcttttt caatcacttc
    81481 ggctaattgc tctcgtcttt tgtgagagat ttgaaaccct ataggattat tacaagaagg
    81541 cataagaaag acaccatgaa tcttcttttt tctacattcc tgaatcaata tatcaggtcg
    81601 cattccttgc tcgtcaaaat caattggaac gatctctaaa tgatataact gagccaattc
    81661 aatgaaatta gcgtatgtat atcggtctgt tgctattcta tcacctggag agaaaagtgc
    81721 agaaagtgtg atagccaatc cattttgaac accggaaaca atagatagag attctaagga
    81781 cggaatgact ccttgagttt ttaaccaatt tgctgcagta gtcaattgaa aatttgtgcc
    81841 tttgggatct tggtaattaa gcaaaccaac aagatttggg ttattactag ttgattgaat
    81901 aaacgggaca acgaatttat tacattcttc aaaagaacta accagaccaa aatcaatgat
    81961 atgttcggtt acttcattgg tagagatggt gatggactca aagacattgg gagaaataaa
    82021 tgtgccactt ccaatattcg tatacagcaa acctttctca attccatatt tataagcctt
    82081 gccaacggta gtaaaattta aatctaaata atcagctagc tctctttggg agggtaactg
    82141 agtgtttttc tgtaatttat tctttaaaat atcttgttct aattgttgaa tcaacgatcg
    82201 ataataagga cgcttcaatt tttgtttgtc tggtcgccaa gttaacgggt aattgtcata
    82261 agaattaata ggcattttct acactcctta aaattgtata ccatacaatt ttaccattga
    82321 ttgtattgat tttagaagtt aatcttttgt gaggagggaa ttgtctatga aaattattaa
    82381 ttttgaggaa gtagtagctt cttttagttt tgaagaagcg attcaagtaa tgaaaaaatg
    82441 tttttttgat tatgaaagtg gtaaaatcag ccaaaatcct cgattggtgg aaattttacc
    82501 tgacggaaaa gacaaaaata tgtttgcgat gatgcctgct tatttggggg agaacagata
    82561 ttttggaaca aaagtcatta ccgcttttcc ggataatcat cagtatcatt taccttctca
    82621 tttaggagag attttcttgt ttgatgctca aaacggacta cccaaagcat tgataaacgc
    82681 aaatgcagtc acctggattc gaacagctgc tgtatctgcg ctggcaacag attacttagc
    82741 aaatccgcat gcagaaacac ttgctttaat tggagctggt caacaagcat tgtcgcattt
    82801 gactgcgatt tctaccattc gtcccatcac tacagtgttt gtttacgata ttttagaaga
    82861 aagacgaaat acttttatcg ctaaagctaa aaaacagtat cctaaaataa cgtttataaa
    82921 tgcaatatca gtagaagatg cagtacgtcc agcggaaatc atttgtacgt tgacctctag
    82981 taaagaggca tttcttcaaa aagagtgggt aagggaagac gcacatatca atgctgtggg
    83041 cacatttact cctgatacaa gagagataag tacatcgttg atggaaactt ctcaaatcta
    83101 tgtagatgat tactcagcta ccttaacaga aagcggggac ctgcttatag ccatggcaga
    83161 aggagattta gaggaatctt gtattgttgg tacattaggc gaattagttt ctgagaaaaa
    83221 aacattttat aaaggagaat cgaggccgac gattttcgac gcagttggtc tagctattga
    83281 agatctttgt tgtgcagaat atatttataa caaattagag aaaggggctt taaaatgaac
    83341 ttagattatt acgtagttga tgcatttgca gatgaggtgt tcaaaggaaa tccagcagcg
    83401 gtttatgtgc tagaagaatg gctgccagaa ggtacgatgc aaaaaattgc cattgaaaac
    83461 aatttatctg aaacagcatt tacagtgaag aaaaaccaag aatttgagct tagatggttt
    83521 acgccagatc gagaaatcga tctttgtggt cacgcgacat tagcaacagc atttgtttta
    83581 tttaactatt acaaaatacc tgatgaaacg attaaatttt ctactcaaag cggtaatcta
    83641 tttgtgacaa gaattaaaga ttattattac atggattttc ctagtattat gccgaaaaaa
    83701 gtgccgatat tgactgaata tgaagaagca attggggcta agattaaaga agcctactta
    83761 gcacgtgatt tatttttcgt attagaagat gaaaaaacgg tggctaaatt gcagccagat
    83821 tttacagcta tcaaaaattt tgaattagga atagagtcat cgtgacagca gaaagtgtgc
    83881 aaaaagactt tgtttctaga accttctttc caaaattaac aatcaatgaa gatccagtat
    83941 gtggatcagc acattctaat cttattcctt attgggcaga aagaatgaat aaaacaaaat
    84001 tgtcagctta tcaaatgtca tcaaggggcg gggatctaga atgtgaatta aaagaagatc
    84061 gtgtgataat aggaggaaaa gcagttttgt tttctaaagg tacctcgttt atttgatttc
    84121 tttcaaatga attaaaaata aattggtgga gagtggcagc cttatagcta caatggttgt
    84181 taaaaaaaga cgcaaacttt ttcaatttaa tgaaaagttt gcgtcttttt ttaattattg
    84241 gtgtttgttt tttattcaat caagagtaaa atgccccata ctaactatcc tcggatgact
    84301 tcgattttat aaccatcagg gtcaatgaca aagtagtaag aaggcgtagt gccaggtaat
    84361 ccttttaagt cagtaatctc aagacctgca gctttatgtt gctcgtgtaa tttttctaaa
    84421 tcatcagctg caatagcgat atgaccatag ccgtctccta gatcatacgc accatgatca
    84481 tagttgtaag tcaactctaa ttcatagtca tctccaggaa gtgtcaaata aacaagtgta
    84541 aatttgtttt ctggaaaatc acggcggcgg ctttcttcaa aaccaaatgc cttttgataa
    84601 aattcgattg atgcttcaag atctttcacc cgaacacatg tgtgagccat tttcataaat
    84661 tcatctctcc ttttcctttt actcaatcat aacaaaaaga agtaagaaaa tagttgattt
    84721 gtgcttgttc atgagaaatt tctcatgtaa aatggataga aaataatact gttaaggtgg
    84781 aaacaattca tggataaacc aatttttggt gaaaaaaagc aatctgctaa ttatcaaacc
    84841 cgttatgcag catatattgt catagaaaga gacaagcgga ttgcggtgat cgaggctcca
    84901 aatggtgctt ttttccttcc tggtggggaa atcgaaggag aagagacgaa agaagaagcg
    84961 attgtccgtg agctgataga agaaatggga attgtggcag aaatttcttc ttatctggga
    85021 gaagctgatg agtattttta ctcgaattat cgtgcaactt attattataa tccaggatat
    85081 ttctttgttg ctgattcttg gaagcgtata ggagaaccaa ctgaaaagac caataaaatt
    85141 tggtgggtga gccctcaaga agcgcttgtg aaattgaaac gtggtagcca ccgatgggca
    85201 gtcgagagat ggatcgaaaa aaataaaaac tgaaagaaag cgagtagatc agctttctct
    85261 cagttttttt atttattaca gtacatattt tttgattgct tcagctacac cgtgctcgtc
    85321 gtttgatgaa gtgatgacat ttgctgcttc tttgacaaga gaaacggcat ttcccattgc
    85381 tactcctaga ccagcatatt caatcatgga taagtcgttc tcgttatctc cgatagccat
    85441 gatttcatct tgatcaatac caaggtgctg tgcgagattc gcaactgccg cacctttact
    85501 tgcttcttta tttagtactt cgaagtaata gggcgcactt ttgaccgttg tgtatttatc
    85561 acggaaagtt tgcggtaaac gcgcaattgc tgcatctaaa atttctggtt cgtcgatcat
    85621 catcattttg acgatgttca tgtctggtgt catttcttca ggtgttcgat attttagcgg
    85681 catcttgact aaacttgctt cgtggatcgt ataagcgctg atatctcgat taggcgtgta
    85741 gatcgctttg tcatcgatcg aatggagatg actgccgaca cggcgtgcca tcacttcgat
    85801 ctctaggaaa tcttcatgag tcagtccgtg acgggcgatg attttacctg atttcgtttg
    85861 ttgtacgagt gccccgttat aagtaataac gtaatcatta tcttgaaaaa ggttcaactc
    85921 gtttaactgt tcctggacac ctggtaaggg acggccagtg cataaaacga tcgaaacacc
    85981 ttttgcaaca gcagcggcaa tcgcttcttt tacttctttt gttacttctc ttttctcatt
    86041 taataaagta ccatcgatgt cgatagcgac tagtttgata gacataattt cctccaatat
    86101 attttaattt atttcaatca atgcgccatt acggatatgg ctggcaaatt cttgataagt
    86161 ttcgtcaaat aaatcataat gatcacgcaa ggagggatca accatttctt ttggaaagaa
    86221 aaatcgctca tctccttgtt cttgtcccgc taatgcagca acaagctgac taacctgtga
    86281 taattctatc aaagttccgt catttcgcaa aatctcgatt tgtgtgcgat gtctgccttg
    86341 ttctgggcga taaaaatcat aaggcagatc gtagctagaa ttcacagcag tgtaataaac
    86401 agggttatag ccaacctttt ctactaacaa agtgagttct tggactaatt ttgaatcccg
    86461 gttgccagaa aaagtagcag atttcagtgg tttacgattc aaaaaacgtt tagctaaatc
    86521 atttaaaata ggatcagcag attcagacca ttgagtaaag taagtgccca agaccccatc
    86581 atcaagtttg aggtattctt ctaaagtaaa gcttccgtca agaaatggca gaagtaattg
    86641 agaatggagt tcaaaactgc tggcatcttc ttgatacaac tcgtgtgcgc gatgaagcag
    86701 atgctccaaa atcacttcca taccacggga aacaggatgg aagtacactt gcacatacat
    86761 ttgatatcgg ctaacgatat aatcttccac tgcatgcatg ccactcatgg aaaaagcgat
    86821 cccgccttca taaggacgaa tcacacgtaa tattcgggta agatcaaatg ttccatattc
    86881 tgttccagtg aaataagcat cccgaagcaa atagtccatt cgatctgcat cgatctgact
    86941 agaaatcatt tggacaactt gtgggttggg gtaagttttt tggatcacac tagctacctt
    87001 ttcaggaaaa ccttcttcta ctcggttaag aatctgatac acttctgttt ctggagaagt
    87061 gatgatctct acagtgatgg cttcatgatt cgtatggaag atatgttcaa atgtatgaga
    87121 gtaaggacca tgaccgacat catgcaacag tgccgcacat aaagtcacca gccgttcctg
    87181 atcatcccag cctccgttgc ctattttttc ttttgaaaaa tttcgagaaa agatatcgca
    87241 gattcgtctt gaaatctcat aaacgcctaa tgaatgggta aaacggctat gttctgctcc
    87301 gtgaaaagtg aaagaagaag tgcctaattg tttaatgcgt cgtaaacgtt ggacttcttt
    87361 cgaattgatc aaatctaaga ttactttatg ctggacatgg atatagttat ggactggatc
    87421 acgaaaaact ttttccatag gcagcatttg atatttataa ggggttgtca taatgtagct
    87481 cctttatgtt attacgttgt tccattctct ggatttggtt gttccattgc tccagctgga
    87541 tttctttttt tagccagtcg gtagaatcct gtaaatcact tgcagaatac agcttttcaa
    87601 aagcttttgc aaatgcttct ttgacttctt ttacaaaaag gggttggtca agcagttctt
    87661 caagtgttgc cattgtagca ggatccactg caggatagcc atttgtacca aagtcttctt
    87721 ttaaagcaga ttgataaaat cgcttcatga cttgcccgcg tttttcctga ttaccgttga
    87781 cacttaagta catcataaca gaaatcccat ttttgatccg acgctgagcg ataccggcaa
    87841 attttttgcc atggatgctt aaatcataag ttccaggaca ataagaatgg gtgatttcga
    87901 atgcttgtat cggtgccttt ggaaaagcgt atttagtcaa taggagcatt tgctcgtaag
    87961 cgtcatctat ggttattttt tttgtgtcac tttgagggaa aatcaaagaa atatttaaaa
    88021 ttccttcatc tgatacgatc cctaatccac ctgaatttct gatcactgga gcgtaacctg
    88081 catctttcag tgtttggatc ccgtcactta gaaaaggagt tcgaacatcc ttcataccta
    88141 agatgactgt gcagtcatat tgccagaaat gtaaaaagat ttgctggtgt tctttagaat
    88201 attccgttaa tatatctgtt aatgcaaaag gggaaaagtc gtttttttga taaatgtgct
    88261 gatctagtcg aatcgcaggg ttcattcaac cggctccttt gtataaattc atattttcta
    88321 caatattata ctctaaaatc aaagagttgt tttggaaaaa aggttttctg taaaaatgga
    88381 caagttggtt gacaaaacaa aagaaactag gaacaatgta gctatgagaa gtaaaggaga
    88441 atgaataatg gaattatcac aaggaacacc gatttcaatc aaattgcgta caaaagtaaa
    88501 acagcaaggg gaagtgcaag atttttattt tgatttgaaa gggcaaatgg tgacaattgg
    88561 cgatacgctg tacatacgtt ataaagagat tcaggaggag acgggcgatg agattcctgt
    88621 aacgatcaaa ttagttccag atggtcatgt acagctgatc cgtgcaggag aaatgcggat
    88681 gcgtttgaaa tttggctata aagaacggtt agaaacatcc tatcgaacac catacggtat
    88741 gatccagatt gctactttta cgaaagaact gcatgttagt ttgaaagacc gtcccacagc
    88801 agggaaggtt cgaatcgatt atgatctgtt catgggaccg gaaaaaatcg gcgaatatta
    88861 tttgaccttg gattttacag cgtaaatata aaagaaaagt ttgatttttt gtgtctgatt
    88921 ttgtatgata aggagtagac tgtgaaagga cgtgtcctga ttggaaatta gtgtatttga
    88981 aggtgcaaac aaaagcgaat tatcaatgat cgaagtagca cacgcgatct tagaacaacg
    89041 tggcgatgtc atggattttt ctgatttagc taaccagatc caaaactatc ttgagaaatc
    89101 agacagtgaa attcgtgatt cactcgcaca attttatact gacttgaata ttgacggcag
    89161 ctttatctca ttaggggata atcgttgggg cttgcgttca tggtatgcta tcgattcgat
    89221 cgatgaagaa gtaaaccatg gaatggacga agaggatgaa gatactccac gtcgccgtaa
    89281 acgcaagaaa gtcaacgcct ttatcaatga tgatgaagac gcgatcgatt acaatgacga
    89341 tgacccagaa gatacagatc tgacagaaga agatgacgat gatctgtttg atgacgatga
    89401 tgatgaagat gaagaaatcg ctgcttataa ttctgacttg caagaaatcg gagcagatga
    89461 cccgacagat gatgaagaag acttgccagg aaatatcgaa gaagatttaa gtatcataga
    89521 cgaagacgat gatgatgaag attatgaaga ggaagaattt tctgactctg aaaaagaata
    89581 aacattattt tcttacgaga ggttgtgaca gagacgatca gcctatcaga ataaggaggt
    89641 gtgacacgat ttttgtcaca ccttcttttt tgtatataaa aatcccaagt aaatacataa
    89701 aaaataaaaa aattgaaact tttagcgcac cttgtacgtc atattaagtg aggcagaaag
    89761 gagtggagaa tgatttttac tggatataag aaaaaacggc agatcgaaaa ataccgtcac
    89821 ctgctgaatg gactcatcga aactgattat caaaaaatgt tccgtatcac gatgaattac
    89881 gtacatgata aagaagaggc cttagatgtg atgcaagata gttttcataa agccttgaac
    89941 tattttgaaa aagaaaaaga gatcgagcat tttagtgcat ggttttatcg gatattgatc
    90001 cgcacggcat tagatagttg gcgcagacaa aaaaggacgc ctgtggactt atttgaaatt
    90061 caagatatcc cccaacagtt acctttagaa acttccgttg cagagctcca tatgatttta
    90121 gataaaatag acagtccgga aaaagagatt ctgatcctct acttttttga aggatttcgt
    90181 ttgaaagaaa ttgcaactat cttggatatg aatgaaaaca cagttaaaac gaaaatgtac
    90241 cgctcattga atgctttacg tcaaatccta gaatgaagga gagaagagtg ccatgtattc
    90301 ccaaaaagaa aatttaaaaa aactaaagaa aacttataaa gaacaagcaa ttcccaaagg
    90361 gcttaaagag gagatccgcc agcgttttat tatcgaagag caatcattta taaaagcaag
    90421 gcggagaaag agacgtctcc aagggttcgg agtatctttg gctatcgtaa tgattacaac
    90481 aagtagcctt ctttttaata gtcaagttcg aagctttgca gaagatttac ccatcttagg
    90541 atcagtcatt gaattgatct taggcgaacg ctttactgat cgatctgaaa aaatcgatat
    90601 tcaggtaccg aagatcaata cacaaaatga gaaagaaaat aaaacaattc atggattaaa
    90661 tcaaaaatac tttcgcgaag gacaagcaga ttttgaaaaa gctgaaaaag aatatggaaa
    90721 ttttgaaacg gatcattacc aagttttggg agattatcag aaaatcgtag acgataaccg
    90781 gtttctcgtg attgaaaggc agatcaccca aacagcagca gatagccatg ttgaaaaaag
    90841 atacgacaca atcgacaaga aaaacagtgt ccagctctca cttccacttt tattcaaaga
    90901 tgacacttat ctatctgttt tgacaaaaga agtcaaacgg cagatggccg aacaagtcaa
    90961 ggaagatcca tctaagtact attggactga gcaagatatt caagaaggga cgatagaaaa
    91021 accaacactt gttacgccta cacgaagttt ttatttgaac aaagagcatc aattagtttt
    91081 gactttttct caatacgaaa ttgctcctgg ttatatgggt acaccagaat ttgtcattcc
    91141 taagtccgtg acaaaaacga ttttggcatc ggaagattat ttggatcatt agacgagaag
    91201 tagttgcgac tagcagtttc aattttcaag taagtacaag taaataataa gaagagaaaa
    91261 agagaaagaa gagatatagt gaaaagaaat tatttagtca tcagtattat tgctttatcc
    91321 gtgcttttgt ttttcgaaat tacttcggtg gcctccttga tcaccgaagt aaaaggacaa
    91381 acacactctt cggagcattc gtcacaatct ttcaaacaat cagaacaatc aaccattaaa
    91441 agccaatcaa ctgaaacagc taacgtcaaa gaagccattc aagaatcagc ggaaaaggta
    91501 caaagtcaat catcacaatc aacacaagac agtacagaag caatccaaga cccgactgtc
    91561 aaaagcgtcg caatcagctt tgatgatgga ccaggagcga ccacaacgcc gcagcttctg
    91621 cgaatcttaa aagaaaaaaa cgtgcatgtc acttttttcg tcttaggaga aaatacggcg
    91681 cagcatcctg aaatcgtgaa gcagacagct gaagcagggc acgagattgg caatcacaca
    91741 tacgatcatc agaatctggc cactctttct gcccagtcga tgacggagga agtgacgaaa
    91801 gcagacactg agatcaaaaa aagtcactgg caaaaccccc gcttttgttc gtccgcccta
    91861 tggttctgtc acgaatgtag gagcaacgat catccagcga ccgatcatcg aatggtctgt
    91921 tgattcagaa gattggaaga caaggaatcc tgatttgatt ttgcagaaga tccaagcaac
    91981 agtatacgat gggtcaatta ttttattcca tgatatctat cctgaaacga ttcgtgccgt
    92041 tcctcaagtg atcgattatc tgaaagagca aggctatcgc atcacgacag ttagcgattt
    92101 attagggcat ccaacggctg tcgagaacta ttatggcaga aacgatcatc ggccagttca
    92161 gtaagtgaga caagtatctt taataaataa cacattttaa taagtagttg aacacataac
    92221 taccttactt gcaaaggctt aacaatatct atacagatac aacaaaaaac tgtccaccaa
    92281 ttctctttgg cggacagttt tcacttaaaa ataaagaagc aactattcgt aaattatgct
    92341 aaaatagcag tagaacgcgt cctgagggaa tcgaaccccc gtctcaagaa ccggaatctt
    92401 acgtgatatc cactacacta aggacgcaag cactgggata attgtaacta aacagataaa
    92461 aaattacaag gggattggac aaaaaaatga aatttgagca aaatttttca caaaaacagc
    92521 agcagacaca gaaactagcc atgacgcaac agttgcaaca gtccatccaa gttttacaat
    92581 ataacagtga ggagctgttg gcattcgttg agaatcaagc aatggaaaat ccattggtgg
    92641 aagttgttga gccggaatgg cagccagatt acataaaagc ttcttcatct tcttatgaag
    92701 gagaagagac aaattaccta aatcagattc ctgatacaaa agggtcttta tttgattcat
    92761 tgatcgaaca agtccatttg aattaccgag atactttttt gaggaaaatc gttctttatc
    92821 ttgtagaata catcgatttg aacggatttt tgacgattag tttagaagaa gccggaaaag
    92881 agattggagc tacgcctatc caaatgctcg atgcgttgac tctgattcag caattagaac
    92941 cagctggagt aggtgcacgt agtttgcaag aatgtctcat gcttcaaaca gaacgagatg
    93001 attatgcgcc ggaattagct tatatcgtgt tggaagaatg ttttgaggaa ctggtggagc
    93061 gaaaatggaa agaaatcgca caacgttttt ctgttgatct acatgctgtt cagcagatat
    93121 tcgactattt acaaacgttg agtccaagcc ctggccggat tttcgaccgt agcagcgaat
    93181 tgtacattat tcctgatgtc cgggtattag tggacgacga taaaaatgta caagttatct
    93241 caaaccgaaa aaatcagcca aatatacgct ttcaagagag ttacttcaaa caaatgtcac
    93301 aacaagcaga taaagaaact gaaaattatt taaaagaacg gaaacaggaa ttcgaatggt
    93361 tgaagaaaac gatcctccaa cgtggggata caattttgcg ggttgctcaa gtcattgttt
    93421 cccggcaaaa agctttcttt atcgacaagg aacgtccaat caagcctctt acgttaaagg
    93481 aagttgcaac tgagatagat gtgcatgaat ccacggtcag tcgtgcagtc aacgggaaat
    93541 atttggaaac agatttcggt gtatttgaat taaaaaaatt tttcactaca cgaattccta
    93601 cgaatagtac agaacagaca gaagaccttt cagcagatac agcgaagaaa aagctgcagg
    93661 aattagtcga tcaagaagac aaaaacaagc cgttgtcgga ccagaaattg gttgaattgc
    93721 tgaaaaaaga tgagatagcg atctcaagac gaacagtagc aaaatatcgt gatttattag
    93781 gaatcccgag ttcatcaaaa agaaaacgtt atgataacta atcagtcaaa agactagaaa
    93841 aagtatttca ctttttctag tctttttagt tgaaaaacga gagcaaaact gttagactta
    93901 cagtcgtgag gttgagattt ccctttattg atgtgaaatt cgaatagtta atttcttttt
    93961 ttatcgtata tgggtcgttt taagtctaca ttggacgtaa agtgtccaac taaggagatc
    94021 gctatgctgg atgaaataaa aatgattgaa tctgttgcac cagatattat cgaagtgttg
    94081 caagaacgct ataaaatttt acgaaatatc tattggatgc agccgattgg gcgtcgaagt
    94141 ttatcggaaa gtatggggat cacagaacga gtcttacgaa cagaaacaga ccttttgaaa
    94201 aatctgaatt tgatcgacac ctcaaaaagc ggtatgacgc tgacaactaa gggcgaagaa
    94261 gtttatcaaa gccttgaaaa cttcatggat cagcttttag gtacgcatca aaccgaacaa
    94321 cagttggcag aatattttgg taaccaacgc tgtatcgttg tttcaggaaa cagcgaagag
    94381 cagaccaaag tggctgatgc attcggcgaa gcgctgagcg aagccttaga ccgactactt
    94441 ccagaaggcg agaatatcat cgctgtgatg ggaggaacta ctatggctgt ggtagccgaa
    94501 caattgtcta atctggaaaa taagaaacgg cataacctgt ttgtccctgc aagaggcggg
    94561 attggtgaag cgataactgt acaggcaaat tctgtcagtg caagaatggc tgctaaagca
    94621 aacggtaacc accgcgcact ttatgttccg gaacaattaa gtctggcaac ttacaattct
    94681 ttactcaatg agccatctat ccaagaagtc ttaaacttga ttagtgaagc gaattgtgtt
    94741 attcatagta ttgggcgtgc attacacatg gcagcacgtc gtaagatgac tgaaaaagaa
    94801 ttagtcatgc tgaaacaagc aaatgctgtt gcggaatctt ttggctactt tttcaatgaa
    94861 aaaggtgaag tcgtttataa ggtccctaga atcggcatag aattgcaaga tttggaaaaa
    94921 gtcccgatca tcatggcaat cgcgggcgga aaatcaaaag ctaaagcaat tcgagcttat
    94981 atgaaaaatg caccaaaaca aacgtggctc atcactgatg aagctgctgc aaatgagatt
    95041 ttaaaagggg taacccttta aaataaatat ttttttgatt ttcataagga ggaaatctta
    95101 aatgacagtt aaagtaggta ttaatggttt tggacgtatt ggacgtctag cattccgtcg
    95161 tatccaagat gtagatggaa tcgaagtagt agcaatcaac gacttgacag atgctaaaat
    95221 gttggcacac ttgttaaaat acgacacaac tcaaggacgt ttcaacggaa cagttgaagt
    95281 tcatgaaggt tcattcaacg taaacggaaa agaagttaaa gtattagcta accgcaaccc
    95341 agaagaatta ccatggggcg aactaggcgt agatatcgtt ctagaatgta ctggtttctt
    95401 cacttctaaa tcagcagctg aaaaacattt aacagctggt gctaaacgcg ttgttatctc
    95461 tgctcctggc ggaaacgatg ttccaacaat cgtttataac acaaaccacg aaacattaac
    95521 tggtaaagaa acagttatct caggtgcttc atgtactact aactgtttag ctcctatggc
    95581 taaaacattg aacgacaaat ttggtgttgt tgaaggatta atgacaacta tccacgctta
    95641 cacaggtgac caaatgactc tagacggacc tcatcctaaa ggtgacttcc gccgtgcacg
    95701 cgctgctgct gcaaacatcg ttcctaactc aacaggtgct gctaaagcta tcggtttagt
    95761 aattcccgaa ttgaacggta aattagacgg agctgctcaa cgtgttcctg taccaacagg
    95821 ttcattaaca gaattagtaa cagttcttga aaaagaagta actgttgacg aaatcaatgc
    95881 agcaatgaaa gaagcttcaa acgaatctta cggatacaac acagacgaaa tcgtttcctc
    95941 agatatcgtt ggtatgactt acggttcatt atttgatgct acacaaacta aagtaatgac
    96001 agttggcgac aaacaattag ttaaaactgt tgcttggtac gacaacgaaa tgtcatacac
    96061 tgcacaatta gtacgtactt tagaatactt cgctaactta taagatagac aaacgtacaa
    96121 gtgtaaatta tagacatgta catttaaaag cggggaagca atcgcgcttc ttccgctttt
    96181 tttgataata agtttattca ggaggaaata aaatggctaa gaaaacagtg aaagatatcg
    96241 atttaaaaga caaaaaagtt cttgtccgtg ttgacttcaa cgttcctttg aaagacggcg
    96301 tgatcactga cgacactcgt atcaaagcag cattgccaac aatcaactac gttctagaac
    96361 aaggcggaaa agcaatcctt ttctctcacc ttggacgtgt aaaaacagaa gaagataaag
    96421 aaggaaaatc tttagctcca gttgcaaaac gtctaggcga attattaggt aaagaagtaa
    96481 cattcgtacc tgaaactcgc ggagaacaat tagaagaagc aatccgcaac atgaatgacg
    96541 gcgacgttgt cgtattcgaa aatacacgtt ttgaagatat tgacggtaaa aaagaaagca
    96601 aaaatgatac agaactaggt aaatactggg cttcattagg cgatgtattt gttaacgatg
    96661 ctttcggtac agctcaccgt gcacatgctt ctaacgtagg tatcgcttca actggtatcc
    96721 caacagttgc tggattcttg atggaaaaag aaatcaagtt catcggtgaa gcagtagaag
    96781 aaccaaaacg cccaatgatt gcaatccttg gtggcgcaaa agtttctgat aaaatcggcg
    96841 taatcgaaaa cttgattcct aaagcagata aaatcttaat cggtggcgga atgacttaca
    96901 cattctacga agcaaaagga atcaagatcg gtaactctct agtagaagct gataaagtag
    96961 aactagcaaa agaattaatc gaaaaagcag gcgacaaact tgtcttgcca atcgacaatg
    97021 tctgtgcacc agaattttca aatgatgttg aaacacaagt aatcgaagga gacattcctg
    97081 atggtttgat ggctttagac atcggcccag catcagtaaa attatttgct gatacattac
    97141 aaggtgcaaa aacagttgtt tggaacggac ctatgggtgt atttgaaatg agtaactttg
    97201 ctaaaggtac aatcggtgtt tgtgaagcaa tcgctaactt agaaggcgca acaacaatca
    97261 tcggtggcgg agactcagct gcagcagcag aacaattagg attcgctgac aaattcacac
    97321 acatctcaac aggtggtggc gcaagcttgg aattgcttga aggtaaagaa ttaccaggac
    97381 tagcagcaat caacgataaa taaacgacca agtttgctca attctgacga gtaatcgatc
    97441 aaaaggtgaa gggagttttc atgactccct agccattttt caataaatta aggagtgtgt
    97501 tcctcaatgc gtaaacctat tatcgcaggt aactggaaaa tgaacaaaac tgcatcagaa
    97561 gcaaaagaat ttgctgaagc agtaaaaaac aaaatccctt caaatgacaa agttgattca
    97621 gtcatcggat ctcctgcatt attcttacaa gaattaatga catcagctga aggtacagaa
    97681 ctaaaaatct cagcacaaaa ctgctactgg gaaaactcag gtgcgttcac tggtgaaact
    97741 tcaccagcag ctcttgctga tctaggtgtt cattatgtga tcatcggaca ttcagaacgt
    97801 cgtgaatatt tccatgaaac agacgaagac atcaataaaa aagcaaaagc tatctttgca
    97861 aatggtatga caccaatcct atgctgcggc gaatctttag aaacctatga agcaggcaaa
    97921 actgctgaat ggatcgaagg acaaattaca gctggtttag ctgatctttc agctgaacaa
    97981 gtgtcaaaca tggttattgc ttatgaacca atctgggcaa tcggtactgg taaatcagct
    98041 gacgcacaaa tcgctgacga aatttgtgga gttgtacgtc aaacagttga aaaactttat
    98101 ggaaaagaag tatcagaagc agttcgtatc caatacggcg gttctgtaaa accagaaaat
    98161 attgctgaat acatggcaaa agaaaatgtt gacggtgctt tagtcggtgg cgcaagcttg
    98221 caagcagatt cattcttgtc attgttagac gctgtaaaat aattgttgaa aatttgtgaa
    98281 aaatgcaaga aatgtttgca ctaatgagca aaattaacta aaatcgtata tgagggaaat
    98341 cccttaggaa aaaacaaact caaaggagag acaaaacatg tcaattatta ctgatgttta
    98401 cgctcgcgag atcttagact cacgtggtaa cccaacaatc gaagtagaag tatacacaga
    98461 aagcggagct tttggccgcg gaatggttcc ttcaggtgct tcaactggtg aatacgaagc
    98521 agttgaatta cgtgacggag acaaagctcg ttatggcggt aaaggtgtaa ctaaagctgt
    98581 cgacaacgta aacaacatca ttgctgaagc aatcattggc tacgatgttc gtgaccaaat
    98641 ggctatcgac aaagctatga tcgctttaga cggaactcct aacaaaggta aattaggtgc
    98701 gaacgctatt ttaggtgttt ctatcgctgt tgcacgtgca gctgctgact acctagaagt
    98761 acctttatac cactacctag gcggattcaa cacaaaagta ttgccaacac caatgatgaa
    98821 catcatcaac ggcggatcac atgctgataa ctcaatcgac ttccaagaat tcatgatcat
    98881 gcctgttggc gctccaacat tcaaagaagc tctacgtatg ggtgctgaag tattccacgc
    98941 attagcttca atcttgaaag ctcgcggatt agcaacttct gttggtgacg aaggtggatt
    99001 tgctccaaac cttggttcaa acgaagaagg ttttgaagta atcatcgaag caatcgaaaa
    99061 agctggctat gtacctggta aagacgttgt tcttgctatg gatgctgctt cttcagaatt
    99121 ctacgacaaa gaaaaaggtg tttacgtact agctgactca ggcgaaggcg aaaaaacaac
    99181 tgacgaaatg atcaaattct acgaagaatt agtttctaaa tatccaatca tctcaatcga
    99241 agatggatta gacgaaaacg actgggacgg attcaagaaa ttaactgacg tattaggcga
    99301 caaagttcaa ttagttggtg acgacttgtt cgtaacaaac actcaaaaat tatctgaagg
    99361 tatcgaaaaa ggaattgcta actcaatcct tatcaaagtg aaccaaatcg gtacattaac
    99421 agaaactttc gaagctatcg aaatggctaa agaagctggc tacacagcag ttgtatctca
    99481 ccgttctggt gaaacagaag attcaacaat ctctgatatc gctgttgcaa caaacgctgg
    99541 ccaaatcaaa actggttctc tatcacgtac tgaccgtatt gctaaataca accaattact
    99601 acgtatcgaa gaccaacttg gtgaagttgc agaatacaaa ggtttgaaat ctttctacaa
    99661 cttaaaaaac aaataattct tttctaatga agatacatga tcgactattg aaagatagtc
    99721 gagtatgatc acttagttaa gtaatcgaac tctctacttg ctgaaat
//
LOCUS       DAPBCF010000005        92246 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.005, whole genome shotgun sequence.
ACCESSION   DAPBCF010000005 DAPBCF010000000
VERSION     DAPBCF010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 92246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.005"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(542..976)
                     /locus_tag="RD508_000418"
     CDS             complement(542..976)
                     /locus_tag="RD508_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735046.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(993..2198)
                     /locus_tag="RD508_000419"
     CDS             complement(993..2198)
                     /locus_tag="RD508_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HDT7735047.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            2892..3278
                     /locus_tag="RD508_000420"
     CDS             2892..3278
                     /locus_tag="RD508_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7735048.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            3372..3563
                     /locus_tag="RD508_000421"
     CDS             3372..3563
                     /locus_tag="RD508_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7735049.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            4077..4409
                     /locus_tag="RD508_000422"
     CDS             4077..4409
                     /locus_tag="RD508_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7735050.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            4705..4860
                     /locus_tag="RD508_000423"
     CDS             4705..4860
                     /locus_tag="RD508_000423"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HDT7735051.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            5136..6476
                     /locus_tag="RD508_000424"
                     /pseudo
     CDS             5136..6476
                     /locus_tag="RD508_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(6717..8333)
                     /locus_tag="RD508_000425"
     CDS             complement(6717..8333)
                     /locus_tag="RD508_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDT7735052.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            8451..8669
                     /locus_tag="RD508_000426"
     CDS             8451..8669
                     /locus_tag="RD508_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7735053.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            8864..9325
                     /locus_tag="RD508_000427"
     CDS             8864..9325
                     /locus_tag="RD508_000427"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7735054.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(9518..9757)
                     /locus_tag="RD508_000428"
     CDS             complement(9518..9757)
                     /locus_tag="RD508_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7735055.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(9781..11304)
                     /locus_tag="RD508_000429"
     CDS             complement(9781..11304)
                     /locus_tag="RD508_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HDT7735056.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(11322..11444)
                     /locus_tag="RD508_000430"
     CDS             complement(11322..11444)
                     /locus_tag="RD508_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HDT7735057.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(11474..12457)
                     /locus_tag="RD508_000431"
     CDS             complement(11474..12457)
                     /locus_tag="RD508_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDT7735058.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(12481..12630)
                     /gene="rpmG"
                     /locus_tag="RD508_000432"
     CDS             complement(12481..12630)
                     /gene="rpmG"
                     /locus_tag="RD508_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDT7735059.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(12651..13028)
                     /locus_tag="RD508_000433"
     CDS             complement(12651..13028)
                     /locus_tag="RD508_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735060.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(13060..13239)
                     /gene="rpmF"
                     /locus_tag="RD508_000434"
     CDS             complement(13060..13239)
                     /gene="rpmF"
                     /locus_tag="RD508_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDT7735061.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(13254..13523)
                     /gene="rpsN"
                     /locus_tag="RD508_000435"
     CDS             complement(13254..13523)
                     /gene="rpsN"
                     /locus_tag="RD508_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDT7735062.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(14046..15812)
                     /locus_tag="RD508_000436"
     CDS             complement(14046..15812)
                     /locus_tag="RD508_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7735063.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(15772..17526)
                     /locus_tag="RD508_000437"
     CDS             complement(15772..17526)
                     /locus_tag="RD508_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7735064.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(17636..18205)
                     /locus_tag="RD508_000438"
     CDS             complement(17636..18205)
                     /locus_tag="RD508_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HDT7735065.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(18223..19638)
                     /locus_tag="RD508_000439"
     CDS             complement(18223..19638)
                     /locus_tag="RD508_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7735066.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(19649..20317)
                     /locus_tag="RD508_000440"
     CDS             complement(19649..20317)
                     /locus_tag="RD508_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDT7735067.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(20447..21031)
                     /locus_tag="RD508_000441"
     CDS             complement(20447..21031)
                     /locus_tag="RD508_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7735068.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(21362..21595)
                     /locus_tag="RD508_000442"
     CDS             complement(21362..21595)
                     /locus_tag="RD508_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HDT7735069.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(21610..22560)
                     /locus_tag="RD508_000443"
     CDS             complement(21610..22560)
                     /locus_tag="RD508_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HDT7735070.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(22557..23399)
                     /locus_tag="RD508_000444"
     CDS             complement(22557..23399)
                     /locus_tag="RD508_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDT7735071.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(23401..24120)
                     /locus_tag="RD508_000445"
     CDS             complement(23401..24120)
                     /locus_tag="RD508_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDT7735072.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            24812..24970
                     /locus_tag="RD508_000446"
     CDS             24812..24970
                     /locus_tag="RD508_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7735073.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            25042..26268
                     /locus_tag="RD508_000447"
     CDS             25042..26268
                     /locus_tag="RD508_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7735074.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(26857..28305)
                     /locus_tag="RD508_000448"
     CDS             complement(26857..28305)
                     /locus_tag="RD508_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013189598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HDT7735075.1"
                     /translation="MDYEIQKFISEKEDQYFDRKSARIKPRDIIKHIVAFANADGGKL
                     VIGIEDDGTISGFKFQGAIDPDEYVLAINSMTKPNPTFKKEMKSIKNARGEDDILFII
                     DVEPSISHVIFNSNGDCFLRIGDKSVHQTHDQISKLEYDKGQRMFEDIEILDSTLDDI
                     DESLMDSYKKLKKAEAISTETILTGRGLMRNGHLTNAGMLLFGKNTFLALPNSRIRFL
                     RYDGKRNETGRRLNIVKEFDYEGAIPKLIESITRDVKTQLREFQYLNDDGKFSIIPEY
                     PEFAWFEGIVNALTHRDYSYKGDYVRINMYDDRLEIFSPGALPNIVTLQNMRRTRYAR
                     NPRIARTLSEFGWVKELNEGVNRIYDEMQLLFLNEPKYSEPNNNSVLLVLENSITSRH
                     LRERDRLDDYLGEFEVDSLSTSEKMIVSHLFNNEKISVKEASEVLKKGVGYSRKVLKE
                     MLRKKIIQWHGTSTKDPTQYYSLNRVKQSKIE"
     gene            complement(28451..29947)
                     /locus_tag="RD508_000449"
     CDS             complement(28451..29947)
                     /locus_tag="RD508_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HDT7735076.1"
                     /translation="MNHQEAKQFFLKTSSFFSTSLPNYIDLSVGIEKAVDLLKNKSFT
                     ELVRHKRSLSEAVDVNHRILANKDGNYAWRPLQILHPLVYVDLVNGITQKNNWNHIKN
                     KFEEFQADKRIECISLPVESISSKSDTAETILNWWENLEQAQISYALEYDYCIHSDIT
                     DCYSSMYTHTIPWAVHSKEWAKTHRKDTQGVGNLIDSKIRYLQNGQTNGIPQGNVLMD
                     FVAEIVLGYADKMLLNKIEKTEIKEFKILRYRDDYRIFSVRKDQAEVIIRLLSEVLSD
                     LNLKLNSNKTFLSDNIILDAIKPDKIYWDLKHASFTEKSNNKWKFKLSLQKHLLQVKL
                     LGDKYPNCGSLSKALSEVYTHRVSTLNKRPDDIYQLISILVNIMQKNPRTLEACIVIL
                     GKLFEFIAVEEINLYLDKILRKFVNTPNTDIVEIWLQRLSLIHSREKSYSAKLCKKVS
                     NPKGFTLWNSDWLKKGFDESGIVNETFISNLSLTTPAKDLELFISQYE"
     gene            complement(30119..30364)
                     /locus_tag="RD508_000450"
     CDS             complement(30119..30364)
                     /locus_tag="RD508_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7735077.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRIRLEKGIGQTELIRDLQLHKIA
                     ITRETLVKIEGGRQHIKLDQLRAIRDILQVSYEDLLQ"
     gene            30469..31242
                     /locus_tag="RD508_000451"
     CDS             30469..31242
                     /locus_tag="RD508_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735078.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSETSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAKLYTEKVEQFFKSGANKDFSKISDYSENFFNETQDEIMNSTFMA
                     EDMYNMTLKKIKAYDHPLNLTLNNGLLSFVLAGYVDYEYSPDYLEKPLQHENNDINFR
                     FVYESKSKTWLVDQLSTINTSFHELPKPENEVEMVIKIF"
     gene            complement(31472..31720)
                     /locus_tag="RD508_000452"
     CDS             complement(31472..31720)
                     /locus_tag="RD508_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDT7735079.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDLMKNEKEDDFKVV"
     gene            complement(31819..32169)
                     /locus_tag="RD508_000453"
     CDS             complement(31819..32169)
                     /locus_tag="RD508_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735080.1"
                     /translation="MIFENESEEIGRMTEENKVDLLETLVINKKEFEQLFLDFFVQYD
                     RIYDFNSSLDLFELEAEIIENSREKNGKIIISVEKFNELFSETFEIDADYYQPQEVFR
                     EFRNKIIGFSQTTK"
     gene            complement(32210..32704)
                     /locus_tag="RD508_000454"
     CDS             complement(32210..32704)
                     /locus_tag="RD508_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735081.1"
                     /translation="MFKVYFPFQWLVKGIFFVLLGLILFGSYLTIKARYFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIELTEKRNEFAQHDRVLQVTYTMKNDTENPIRPQQW
                     SIENKDGEELYEYAMILDNPEYIESGKSETVNYYYELPIERQDYQIVVRRANGYFVGL
                     PFNL"
     gene            complement(32697..32999)
                     /locus_tag="RD508_000455"
     CDS             complement(32697..32999)
                     /locus_tag="RD508_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735082.1"
                     /translation="MSDPYIKVYCSKETKKLFDSFYEKNKGTLGTKANMFRVMVSNLP
                     MLASQSNKKFSDPESIKLEQTISELESSIMKKLDGIDQKLSCSLKTKYKTEEKKDV"
     gene            complement(33022..34359)
                     /locus_tag="RD508_000456"
     CDS             complement(33022..34359)
                     /locus_tag="RD508_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDT7735083.1"
                     /translation="MGSIIKIASKSRSIHNTISYMLNKQEDSELVTGIGVSNDLNAIE
                     EFKRTNEIFGDKGKIKLWHFTQSFDPLEDISAEKAHELGVKWAEKMFPNQSILVVTHT
                     DKGHVHNHFGISPNDQLTGKKMDIRKNDIRVLQAWNDNILIDNGINPLDMYKYNHLVA
                     DRENWKEREFRTENKISNREKIKLAVSEVAQYAKNYDDFHAELKKNHSIETYRFAKNQ
                     RIGYKLLDSEGELILKIGGKRLGQNYDMNYLDDLFTENKKAEQIQSKEVLTEIAIRHL
                     GKSLNGRADSRFNWQERAQRFELDNENIPFLRSSKDYEEFYDKYKFEIEDRIENLLDV
                     FGENKNQFFGFAVEEEPLKYKKKCVNLVYKKVVYDIAESLSTDYDQFNIQDTEPALKR
                     NFKKRYIQETKRVLYLFNRAIDDGTIEKARREYEETARGIDYQKQQNQYDMDF"
     gene            complement(34344..34841)
                     /locus_tag="RD508_000457"
     CDS             complement(34344..34841)
                     /locus_tag="RD508_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735084.1"
                     /translation="MAIDVSKLPLEERRKRYKRNEDSRRQNRPIKFRVDDYQYQELEK
                     TADIFGLSVPMYVKKIAVDNAGKSLKYTDRQYKEINFHLLAIGRNLNQLVKTANYLRV
                     QLNKKDTEIQKEEHQSVYLSFTTKQERLKRLYAEKNDLMIQIKSISDPLNRLEKELNK
                     LWARL"
     gene            complement(34990..35328)
                     /locus_tag="RD508_000458"
     CDS             complement(34990..35328)
                     /locus_tag="RD508_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735085.1"
                     /translation="MARKKQKSIADLKKELAELERKLYPELGKYVYEKTGISSVKEFE
                     ETFEINQKGTQEKWQKAVNFANSEFTLVHEFLASDQLMETKFQQFLRRKGETAYRIFY
                     REEAQEESVR"
     gene            complement(35332..35517)
                     /locus_tag="RD508_000459"
     CDS             complement(35332..35517)
                     /locus_tag="RD508_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735086.1"
                     /translation="MQLILQISTHDFLELDELCESVKKATNEKITVTNYIELMIQEEL
                     MMKNELMNELSHIQKGA"
     gene            complement(35531..38083)
                     /locus_tag="RD508_000460"
     CDS             complement(35531..38083)
                     /locus_tag="RD508_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735087.1"
                     /translation="MKIIKKKIDNRKINWLLISFLILIAMIIFTSNVAEGSIFNWFDD
                     TESQTEFLTNPLYQNYLKKYNGNFYSQFGMWIGWSVIKSMFAVVDGIQNMIPEVLDLF
                     SFVESAGLNKVYQSVLNTVVIGLMVLSLVIIGYKMVTGKGTVDLKSVGMNVVMSIVLI
                     LLMPTLIGSTEKLSGIMFAKTLYNDATSINNQDGGVAWSLIEQGVTDLAYINKTDQYS
                     MIDKTNDRNNLTKENFWKTDLTQVLTDNVIDKMEKENSTADNLRYELVENSDNEFVAT
                     KFSDNFLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRV
                     LGVLVFATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFINYLNTGEGISTNIF
                     IKTIAYICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRS
                     KGGKNSGGNDQTEGEERKPERNFGQSLSQKANKTGKTLGYARERGLSGLASDGATMAS
                     ERATKPFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPIVAKNKEDETGKYADSMPI
                     RLSDRKDGAKIENADRIMSSSERMREAMKNIAESNTNYASAIQQKVQQDIEERKNAMH
                     GQAKSAEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANMDEKEALTKERIQEAKN
                     SNTGLEKSVKENLQNSTSSQDRRSVDVRENLHNTTSSQSGNRTVDVRENVQSSSTGQT
                     RTVDVRLNLQDTTSSQSGNRTVDVRENVQSSAPNQPKTVEVRETRAEASQGDKTQKIN
                     IVEERKERPNEKVIVEQEVKEKKRQRFTYENNPLFQDISDKPNPLFDSLFKK"
     gene            complement(38070..38288)
                     /locus_tag="RD508_000461"
     CDS             complement(38070..38288)
                     /locus_tag="RD508_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735088.1"
                     /translation="MIENHLVDKIYCLDHNADTLELIESICSNTIVLDLRAVNDDYVT
                     HIIVNKKMAQKLSESLKKWAEGGNNENN"
     gene            complement(38281..39021)
                     /locus_tag="RD508_000462"
     CDS             complement(38281..39021)
                     /locus_tag="RD508_000462"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735089.1"
                     /translation="MREKLKKLGDKKRHTFQGTFEFNGYKKDKYKFGQEYENATFMLS
                     NLKIVQGDNLELVTDHIWMNLTKQFLKFGWLKKGDMVQFDGRIKSYSSKKGINYKIER
                     PSKVKVFRKGTEINESSALKISTRYEIVEDIKRQNREYYEARDFFFENYFSVPRYFKL
                     KEKWPEIQAVVAINENRYTSEQFKQVFKDRDSLVDLYKKIQETDKYNLQKEFYNGLVS
                     NKNRIDLNEVEGYLHKIENFDYGRGYFD"
     gene            complement(39154..40029)
                     /locus_tag="RD508_000463"
     CDS             complement(39154..40029)
                     /locus_tag="RD508_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
                     /protein_id="HDT7735090.1"
                     /translation="MAEKRMLAKSFLNNASFMKMSDSAKLLYVYLNTNADDDGIVEAY
                     PYTKMLGTPDDDVKILFTKGFVFFLNEDLLAFLPHWLQNQNIRIDRYKPSIYRFKLLN
                     LKPEFFSKLKPIKFDMILQSGQVEPLRVDLMEKWYPAGIPCDVKSDTQLSQDQNSQDQ
                     TNQDKDSIEEINQDQNSFFENIINQKGIQIITRLGDRYTEVQREKYLKLIASMKDSIE
                     REYKIEIRGQDYFDITNKMLTRLFNSINEKLNLGEEIDEMKFINTTARNHWEDIAKQE
                     KASRLDMLETLKKIG"
     gene            complement(40199..40480)
                     /locus_tag="RD508_000464"
     CDS             complement(40199..40480)
                     /locus_tag="RD508_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735091.1"
                     /translation="MEQIGVSVMLNTDQTNQLKTHVFEVTKEAIDQARIDSGLERPFL
                     KGKEMAKFLNVSYGTFLKFKRLGLPIIVVDTIELYSKEEVKKWMLQHQI"
     gene            complement(40535..40732)
                     /locus_tag="RD508_000465"
     CDS             complement(40535..40732)
                     /locus_tag="RD508_000465"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7735092.1"
                     /translation="MFQINEDFSIRIRERRGKLMITKTKAAELIGISRQTLKKIECFE
                     VQSVSKNVYQKIIGWLLKSDY"
     gene            40899..41273
                     /locus_tag="RD508_000466"
     CDS             40899..41273
                     /locus_tag="RD508_000466"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7735093.1"
                     /translation="MTQKNRIKETREEQNLTLKELSNLSDIPYQTLRNYEIGKRKPRN
                     DEVWWKLGTILNVRGPYLKGEDSFKTNDELHIYYLKKSHTNFELSKKEEIIDIIDKLN
                     EDGLDEALRQLALLSKIDDFKR"
     gene            41363..42529
                     /locus_tag="RD508_000467"
     CDS             41363..42529
                     /locus_tag="RD508_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7735094.1"
                     /translation="MSIQKYKTKSGTRYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDMGYHRPSNDLFRTVYEEWLPSYKNRVQETTYQRTKDLFRLHILPKFG
                     DKSISKITPIYCQNAINEWAVKYTNIKQLKSYSSQIFEYAIFAELLQRNPMTNTKLPK
                     QEKKESENYFSLEELKEFLEILNKEESLKHILIFQLLITTGVRKGELSALRWADINFE
                     EQLLHIGKSYATIRTEDPNATRKTIRIQKNTKNVSSERILPIDTQTIEMLKLWKKEQA
                     EVLLQFGINANTKKQLIFTYVNANGDVNQPLHADYSNNIMRRLEKKYKFKHVTIHGLR
                     HTHATLLLEGGASIKEAQDRLGHKNAETTLNTYSHVTEKAQRNAVDKFIAYTGL"
     gene            complement(42628..43020)
                     /gene="rpsI"
                     /locus_tag="RD508_000468"
     CDS             complement(42628..43020)
                     /gene="rpsI"
                     /locus_tag="RD508_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDT7735095.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(43036..43479)
                     /gene="rplM"
                     /locus_tag="RD508_000469"
     CDS             complement(43036..43479)
                     /gene="rplM"
                     /locus_tag="RD508_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDT7735096.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(43998..44465)
                     /locus_tag="RD508_000470"
     CDS             complement(43998..44465)
                     /locus_tag="RD508_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HDT7735097.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(44585..46123)
                     /locus_tag="RD508_000471"
     CDS             complement(44585..46123)
                     /locus_tag="RD508_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HDT7735098.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            46203..46889
                     /locus_tag="RD508_000472"
     CDS             46203..46889
                     /locus_tag="RD508_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDT7735099.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(47090..47617)
                     /gene="msrA"
                     /locus_tag="RD508_000473"
     CDS             complement(47090..47617)
                     /gene="msrA"
                     /locus_tag="RD508_000473"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDT7735100.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(47701..48378)
                     /gene="pgmB"
                     /locus_tag="RD508_000474"
     CDS             complement(47701..48378)
                     /gene="pgmB"
                     /locus_tag="RD508_000474"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDT7735101.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(48375..49505)
                     /locus_tag="RD508_000475"
     CDS             complement(48375..49505)
                     /locus_tag="RD508_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDT7735102.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(49505..51688)
                     /locus_tag="RD508_000476"
     CDS             complement(49505..51688)
                     /locus_tag="RD508_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDT7735103.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(51685..52710)
                     /locus_tag="RD508_000477"
     CDS             complement(51685..52710)
                     /locus_tag="RD508_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7735104.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(52755..53582)
                     /locus_tag="RD508_000478"
     CDS             complement(52755..53582)
                     /locus_tag="RD508_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDT7735105.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(53579..54646)
                     /locus_tag="RD508_000479"
     CDS             complement(53579..54646)
                     /locus_tag="RD508_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HDT7735106.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(54672..55508)
                     /locus_tag="RD508_000480"
     CDS             complement(54672..55508)
                     /locus_tag="RD508_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7735107.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(55505..56374)
                     /locus_tag="RD508_000481"
     CDS             complement(55505..56374)
                     /locus_tag="RD508_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7735108.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(56444..57727)
                     /locus_tag="RD508_000482"
     CDS             complement(56444..57727)
                     /locus_tag="RD508_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDT7735109.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(57741..59426)
                     /locus_tag="RD508_000483"
     CDS             complement(57741..59426)
                     /locus_tag="RD508_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HDT7735110.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            59701..60726
                     /locus_tag="RD508_000484"
     CDS             59701..60726
                     /locus_tag="RD508_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7735111.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(61321..64995)
                     /gene="rpoC"
                     /locus_tag="RD508_000485"
     CDS             complement(61321..64995)
                     /gene="rpoC"
                     /locus_tag="RD508_000485"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDT7735112.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(65053..68670)
                     /gene="rpoB"
                     /locus_tag="RD508_000486"
     CDS             complement(65053..68670)
                     /gene="rpoB"
                     /locus_tag="RD508_000486"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDT7735113.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            69398..70366
                     /locus_tag="RD508_000487"
     CDS             69398..70366
                     /locus_tag="RD508_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7735114.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            70384..71289
                     /locus_tag="RD508_000488"
     CDS             70384..71289
                     /locus_tag="RD508_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7735115.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            71286..72092
                     /locus_tag="RD508_000489"
     CDS             71286..72092
                     /locus_tag="RD508_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7735116.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            72228..73217
                     /locus_tag="RD508_000490"
     CDS             72228..73217
                     /locus_tag="RD508_000490"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HDT7735117.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(73534..74058)
                     /locus_tag="RD508_000491"
     CDS             complement(73534..74058)
                     /locus_tag="RD508_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HDT7735118.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            74345..76156
                     /gene="scm"
                     /locus_tag="RD508_000492"
     CDS             74345..76156
                     /gene="scm"
                     /locus_tag="RD508_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HDT7735119.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSS
                     TTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKR
                     ALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(76311..77297)
                     /locus_tag="RD508_000493"
     CDS             complement(76311..77297)
                     /locus_tag="RD508_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDT7735120.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(77320..77886)
                     /locus_tag="RD508_000494"
     CDS             complement(77320..77886)
                     /locus_tag="RD508_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HDT7735121.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(77900..78316)
                     /locus_tag="RD508_000495"
     CDS             complement(77900..78316)
                     /locus_tag="RD508_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDT7735122.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(78773..80707)
                     /locus_tag="RD508_000496"
     CDS             complement(78773..80707)
                     /locus_tag="RD508_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7735123.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            80988..81944
                     /locus_tag="RD508_000497"
     CDS             80988..81944
                     /locus_tag="RD508_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HDT7735124.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            82034..83137
                     /locus_tag="RD508_000498"
     CDS             82034..83137
                     /locus_tag="RD508_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HDT7735125.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            83150..84103
                     /gene="menA"
                     /locus_tag="RD508_000499"
     CDS             83150..84103
                     /gene="menA"
                     /locus_tag="RD508_000499"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HDT7735126.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(85038..86384)
                     /gene="gor"
                     /locus_tag="RD508_000500"
     CDS             complement(85038..86384)
                     /gene="gor"
                     /locus_tag="RD508_000500"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HDT7735127.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFCGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(86518..87771)
                     /locus_tag="RD508_000501"
     CDS             complement(86518..87771)
                     /locus_tag="RD508_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDT7735128.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(87777..88700)
                     /locus_tag="RD508_000502"
     CDS             complement(87777..88700)
                     /locus_tag="RD508_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDT7735129.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(88921..91413)
                     /locus_tag="RD508_000503"
     CDS             complement(88921..91413)
                     /locus_tag="RD508_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDT7735130.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(91420..91887)
                     /locus_tag="RD508_000504"
     CDS             complement(91420..91887)
                     /locus_tag="RD508_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HDT7735131.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(92023..92096)
                     /locus_tag="RD508_000505"
     tRNA            complement(92023..92096)
                     /locus_tag="RD508_000505"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(92060..92062),aa:Arg,seq:acg)
     gene            complement(92154..92227)
                     /locus_tag="RD508_000506"
     tRNA            complement(92154..92227)
                     /locus_tag="RD508_000506"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(92191..92193),aa:Pro,seq:tgg)
BASE COUNT        27963 a        18560 c        15078 g        30645 t
ORIGIN      
        1 ataggaatct tactaacctt atgttaacta atttacttag agaatttcat gaacattaca
       61 acaaaaaaag tacatttctt catgtttttt tcggatattt gtgcttttta accattcagc
      121 agctgaaaac atataaaaag atatgtatgt attctttctg aaattaagtt catttctatg
      181 cgatgaagca tgttttcaaa atattaccct ttcttagatt aaacttcaga gtattcaaat
      241 aacggaataa ggagccttat cccgcattac tgaatgagac tgtgacataa gtaaaaaggt
      301 gacttcaaat tccttcttcg gaatttgaaa tcaccttctt tataattata aagtatcggt
      361 ttcacagcat ttctgaatga ttcctagaat cttaaacgaa tgattggagt tatcaacatt
      421 ttttcactcg tttttagcga aacaaaaaat gacatttgtc acagcctcat taaattattg
      481 attctttttc tttataattg aattgtccat atttaaagtg tctagtactc tacatgaata
      541 attaattgct ttcactcaaa tacttataat ctattaactt gtagttgttt aacttttctg
      601 aaaaagttag acccacgtaa taatcttccc agctttctct ttcaattaac tgatccaatt
      661 tttgataatc cataaattca tcatgtatca aaaagaataa ataacttgat attttagcat
      721 ctagcttaat cagattaaat aatgtttgtt taaaattgct accattaata tgactgatag
      781 attctctagc ttcttcacat aaacttttta ctttattaat tactactttg tcatattcat
      841 ttaacacact attattacca ttacttagac gctcagattc tacgaaacaa ctcaaatcag
      901 aaatttccca aaaaaatttt ttgttaaaat ccaatttcct caactcctcc aaactacgta
      961 aatgatatag tctcataata aaataaaacc tctcagctaa tgttgttgaa attgtccact
     1021 aaacctaatt gatattgctt aggagataca cctgcgtact ttttgaatac tctcgaaaag
     1081 tgtgaagaat ctgaaaatcc taaacctaaa gaaacttcac tgatagtatg gtttgatttc
     1141 aacattattt tagccgtaga aatttttcgc ttagagatat aattataaat cgtaatatgc
     1201 atttcattct taaagctttc tcttaattta gtttcactta cagaaaaata attagctatt
     1261 tcctttacag taattctttt atagatattt aagccgatga attgaacgac agaagaaatt
     1321 aagggagaaa gatgctctat cttagttttt ccgatttcct tagtataata aacaatccca
     1381 gaatccctca cttttaagac ctcaggtaac gatacagcta attcgttttc ttgtatcaaa
     1441 gcatctctac tttgatacgc ttctattata tccattccta atgttataga cgtttgtgct
     1501 aacttttcaa aaacaatgat agaataattt ttttcagacc gaatcgtatc tccactaaca
     1561 cttggaatta ttccattact cagattaaaa accatgtttt ctaaatttcg aatatctcca
     1621 tttttaacat attccagtat tttattttca taaagaaaca gatatatttc tggatcgtaa
     1681 ttttgtgata acagattatc tattttgatt tgctcgatag ttttacttag attttctgta
     1741 tattcaatta acggttcatg gaatagatct tctatttttc cagtaaaaaa ataatgaact
     1801 aaaatcagaa tatctcgaat gtctcctaaa gaatacaaag tcaaattttg caatgaatta
     1861 tagagtcgtt ctctatcagc cattgcaaca ttcaaattgt tcatttttag tttaaaaaaa
     1921 actttatcaa tattatttgc tctaaatgga ccaaataagt aatatctggt tttaaacatg
     1981 tatagaagaa acatctcatt aaaatcacca gtaaagaaat ggaaatcttt agttttttta
     2041 atattatcag ttagtaactt tttataatca taaaaaaaat aagtagttct atctgagcga
     2101 tactctttta taatactgaa ttcggaatta aaaaccacga taggtaactt taaacaaaca
     2161 tgaagagact ttaataagac ttctttatct gaaaacactt ttgtttctct ctttcctttc
     2221 tacatcatta aatagtattt tatacgttat ctaaaatact attcctctgt caaaataagc
     2281 taacttactt cattataaaa tatccactta tcgctttcat gtatattcca ccgtaaaaag
     2341 tacattttat caccgagaac tcatcatttt tcatcatgat gaatactatt tacatatatc
     2401 tagttcaaag acaataatta ttatgatccg ttattatcta agcactatac agataatagg
     2461 aatttttcgt ttctaaatat tccaatttgg gaatccaata aaaattttcg ttcaaatacg
     2521 tgtctattcg aactcttttc tagttgttaa ttatgaaggg ggaagaaata aaaaatacaa
     2581 tctatacacg aataagaata ttatccaaaa ggaggtttta gaaaagattt attatacgta
     2641 aaaagctcaa gacattttct tagccataag gacatgtttg atatttaaga agatatatga
     2701 attttctttt ctaagtataa agataactat ccattatcaa ctaaaaaaac atttttgaaa
     2761 ataaacatca gcagtcctat caatgcatgt gagcttatag aagttattcg cagcgcagca
     2821 taattgcatt agcttctttt cgtgtttttt gcctcttttc cctttaaatc ttaatggagg
     2881 aggtgtgcaa tatgtcagat aacgacgaac gcgtaaatgc ccagttgatt cgattctttg
     2941 aaaaggtcat tttgaacacc gctaatactt attataaaaa acaagaagaa attcaaaaac
     3001 atgaacaact tgatcaactc ccaccatatt tgtttactaa agatactata aaatttaaac
     3061 aaccgattaa tgttttaaat gtgactctcc ttgttgaaga tataaaatta gcaaaaatcc
     3121 ttcctttgtt gaaagaacct gaacaaattt ttcttatcga aaaatttatc tttgataaaa
     3181 ctgataaaga aattggaaag gttctgggga ttacaagaca gggtgcgaca aatttaaaac
     3241 atcgacttta caaaaaaatt caaaaaatgc tggtttaata tctgcataat aactaatttt
     3301 gtatgcttct ttgctcgttc tcctccttcc caaagaaata gattataagt ccatgggaag
     3361 aaggtagatt tatgaattct ttaaaagaag atttcatttt agcaaaggct ggaaatgaag
     3421 aagctgttga ggcaattctc aaaagattta gctctttgat tcataagcaa tcctggagaa
     3481 ctggaaaata tgatcaagat tgttatcaag aatgtatgct tgcaatatat ctagctatct
     3541 cgaaattcga aattaaagaa taactcaact aagggagtct gtgacataag taaaaagata
     3601 gtttcaaatt tcgaacaata aatttgaaac tatcttcttt ataattataa agtatcgatt
     3661 ttacagcgtt ctataatgat tcatagaatc taaaacgaat gattttaatt atcaacgttt
     3721 tttaattcgt ttttagctta aaaataactt ttgtcacagt ctcactccta aaattacttt
     3781 atttacgtat gaagtgggca ggaggtcgaa tccagaactg ggctatggta cttcaacgag
     3841 gacttctcct ctagaattga aaagcatgcg atttaccttc cgtaacgacg gtagatttat
     3901 tcaactatgt gtccaatcaa aatttgtctg atttcaaaaa tagtcaagag aattttggtt
     3961 gttaaaaact cttatctatc aacttccaca gtttagttga caaaccctga tactaagttg
     4021 ggctatgata cacttttctt gactatcagt tacgttaccg gaaggaatga actctattga
     4081 gaaaaacata tgatcgtaaa tttaaactaa agatttcaca ggatatcctt gagaaaaaag
     4141 taactaccaa gaaaattgct gaagaataca atatctctcg tccaacaatt tcccgatggg
     4201 tttcagaata tcgtcgatac gggaaaaatg cttttgctgg acaaggaaaa agattacctg
     4261 ataaagcaga tttctacatt cttgaacagg aaaataaacg actaaaagag gaagacgagt
     4321 gttctacgaa cacaaagatc gatacggatc tccagggatc actcaaaaac tttacgatga
     4381 aggaatcgaa atcaataaac gtgttgtagc tgttcttatg cgtgaaatga atttatgcac
     4441 aagaggattt catcgacgca aatcttctca tggtagagaa aaaacaatca aagaaatggt
     4501 aaaaaaatgt tgaatcgata atttgaacag aaccaaattg atgctgtttg ggtgatggat
     4561 attacttaca ttccatgtaa tgacggtcgc ctctatttgt ccacctatat tgacttagca
     4621 actcgtattc tacgttacta tatggtagat tcacacatga aaaaagagat tgtcgtccgt
     4681 ccattacaaa tttattaagg agaattgcct acggtaattc attccgatag aggtagccag
     4741 catcggtctt ttatttatca agagctgttg aacgaccacc acatcacaca ttcagtgagc
     4801 caaactggga ctcctgttga caatgcagta attgaagcgt ttcatcgatc aatcaaatga
     4861 gaattaatcg actccaacaa atataaaagt aaaatagaga tgaaggtgtt aatccaagat
     4921 tatttagaag actactaccc aaacaaaaga atccatacaa aatttatgat gactccttga
     4981 caatttgaag cgaagaaaat aagggatcta taatatctag tgttggtgac gccttctgtt
     5041 gccaatactt tttctttttt ctaataaacg caaacagaca ccttaaaatc ctttagaata
     5101 aagtcgacga aaaccattca aaggagtgtt tcaagatgtc ctattcagag tttaccaaag
     5161 agttactaga tattctagac ctaaatctta tctttcatga agatgccttt cgcaaagagc
     5221 gaatcaatga cgaaacatgt tttgtttttg atggcacatt gacctatcaa ccggaggaat
     5281 gctttcatcg ccactatcaa aatgaacaaa cgatcattaa atagggctgg aaaaaagtat
     5341 ccatcttatt gaatgatgtc agtaactaca agaccattct gcggattaac aaacagcgct
     5401 tcaaatgtaa acactgtgga aagacttttt tagcagaaga ttcagttagt gatcgtcgct
     5461 gctccattgc tcgcagagtc aaacaagcca ttcttgagct attaagcgaa cctctttcta
     5521 tgtctttgat cgcacgtatg aagcacattt ctccgaccac tgtcattcga atacttcgca
     5581 gccttcggcc taaaaccatt tctttgagcc agctgttacc agaagtggtg tgtttcgatg
     5641 aattcaaatc agtgaaaaat gtctcgggag ccatgagctt tgtcatgatg gacggcaaga
     5701 cccatcaact gattgatatt gtggaaaatc ggcaactcaa tcctttacgc gactatttct
     5761 tgcgctaccc tataaaagtc cgtgaacaag tgcgtctagt ggtttcagat ttctatacac
     5821 cctatcgcac attggtgaaa gagtgttttc cgaatgcccg aatcgtcgcc gatcgctttc
     5881 atattagcca acacattggt cgggctttta ccaaccaccg aattcaagta atgaagacct
     5941 ttaaaaaagg ggatcgtcgg tcgaagcact taaagaaata ctggaaacta cttcaaaaga
     6001 atgcgtggga attgaaaggt cagcatcgct actggcgtcc gtcatttcga gatcatctga
     6061 cagaagcaga gatagtcgat cggctattat cttatgatga ttccttaaag cgaggctacg
     6121 aagtctacca ggattttctt tccgttatca gaagacaaga tgttcctgaa ttcgtcgcgc
     6181 tcctaaaaga agactacaag gagttgccag agcactacca accagtgttc acgaccttca
     6241 agaaatacca aacagaaatc aaacgagcgt tgcgcgttcc ctattccaac ggccctatag
     6301 aatgtttgaa taaccatatc aaagtactaa aacgaattgc ctatggctat agaaactttc
     6361 aaaactaccg agaacgaatc tttttatatc gaggaaaata ttttaagaaa actaagaata
     6421 ctacccaact gactaaagcc agaacaacaa cacggctaga caagatagct gtctagccgt
     6481 gtgagtatct cgattattct attgaatttc ttcaccaaca ctcattgacg aagagccaaa
     6541 ataagtaatc taaccgactg ttaactaaac cattgcaggt cccgttaaag atacttgtgc
     6601 ctgttgtcac cgcttctttt tcttgtccac aagcgcttaa cacacttaat aaagcccctg
     6661 ctattattaa taataatatc tttttcttat taaaaacctc ctcatctatt tccagattag
     6721 taaatgtagt aatctgtgct ttcttttttc tcaatactaa taactaactt atggggtaaa
     6781 caaatactcg tttgaccggg ttttgagatc catccagttc taaccgcgat ttgatcagga
     6841 ctattatctt ctttaactcg aattcttcca tctttaatct caacaatatt atattgtccc
     6901 ttcgcaggat gataattcac gagtttatga ttgatcttat ccaaatcgaa gcgatccatt
     6961 tccttgccat caattcgaac gatggcatat ttgatagcat cttcagttgt ttcattctcc
     7021 ttttctatag agaatacaaa taagggaata aaagaggtaa taatcaaaat gccaataatt
     7081 atgacatcgc ctatcttgac accagctttt cttaaaaatt tcattaacga tatctggcta
     7141 aacatattag actttttcca tggaaatggt gaaatttttc ggaaattatc tgcattaaga
     7201 gaatcagtta aacaaccctc aagttgttcc ttaatacatt gttgatccat cttcatacca
     7261 ataaaaacta gtttattaat gcgttcacca aacaacggat gccaggcttc cttcaattcg
     7321 ggattttttt gtataatcat ttgacactca attttaggta aactagctac ccaataattt
     7381 aatgattcaa tacttttata gctacccgat gtttcaaaga tcgtcgaaaa atcactatgt
     7441 tgggcaaacc aaagaaaccc ttttgctctt gtaatattgc caggaaaatt tttatccgta
     7501 agatgggcaa atttttgtgc gtcaaggagt aaccgatttc gatagataaa acttgagata
     7561 ccatattctt ctgtttcagg aatatgattt tgatagccaa gctctaactc tttgaaccag
     7621 cccactgaat aggaagtctc atctatatta aaaagatttg tatttagaat tttcgataag
     7681 tctacttcac ctttaattgt cctaattatt ttggcattgg actgtaactt agcaattaga
     7741 ccgttaattt tgtaaatcgt cttggttgac actaagtcac tattatttaa aagtaatatg
     7801 ttacaacact cgaattgatc aattaacaag ccacgaatat cctgttcttc ttcaactaca
     7861 ttaccttcag cttttctttc ctgaatcttt tcacccgttt cgaaattatc ccaaaaacgt
     7921 tttacatcca ctactataat aatggcacca atctctaatc gttgggtcaa atcaatgtct
     7981 aaagggtttt tagctaatat aattgcttga ataattggaa ttggtttgct gattcctgaa
     8041 gcttcaataa caatttgatt caagtcagaa aattgcacta attgatctag ttcaacaatc
     8101 aaatcttcgc gtaatgtaca acaaatgcat ccattcggca tcgaaacaag tttttctcca
     8161 gttcttttaa aacctttctt gtcgactaat accccatcaa catttacttc ccctatgtca
     8221 tttacaatga cagcaatttc ctttccgtga tcaccgtaca gaatatgatt tagaagtatc
     8281 gtttttcctg aaccaagata gccagttaag attgtaatag gtattttttt catagggaac
     8341 ctctttctat accttgaatt tacactttaa gtgcaacaca taaaaatgag tcataatcga
     8401 tatccaacta gtataagttt gtcgagaaca ctcctagaag gaaaataatt atgagccagt
     8461 atcgtcatct tactatactc gaacgagaaa gaatctttct gcttcacgaa gaaggatttt
     8521 ctattagtat aattggcaac gacattcagc atagcccgtt tactatttta catgaactga
     8581 gaagaaacaa gaaaaaaact attcaccttc caaagcggaa aaaaattatg cttatcgaag
     8641 aaaaaaatgc ggacgttatc acattctaaa tgatccgtga gtttggtcaa ttgttcgtca
     8701 tttatttgtc gattttcagt ggtcgccaga ggaaatctcg aatcgtttga agcatgaaca
     8761 tatggacttt tcaattagtt ttatcacgat ctaacgtgca atttgcaatg atcttttcga
     8821 tacagaaccc ctctcacacg gcaataaagg cctgatccgt tcattgcacc atcgaggaaa
     8881 aacaagacat acaaaaaatc atgtcgagtc tcgtggaaag atttgcctta ctcattcgat
     8941 ccatggccgt ccaaaatccg cagatgatag aagtgatttt ggtcattgga aagccgatat
     9001 tgtagctggc aaaactggtg gtacttgttt agtgactttg acagacagaa aatcatgctt
     9061 ccttttagca ggaaagaagg tccccagaaa gaaagccgct tatgtgagcg agaaaatgat
     9121 tgaactttta agcagtattc caaatgaggc ggtcaaaacg atcactccag atagaggaaa
     9181 agaattctcc aatcatttcg cagttacaga agcattgaat aatatgccct tttattttcc
     9241 agatcctcat gcccttggca acaatgaaca aattaaaata cgaatagact cattcgagaa
     9301 tacttgccaa aatcgaaaga gatagctacg gtagataact caacgataaa tcagatgatt
     9361 gaaaaactga ataacagacc tagaaagtgt ttagattgga gaacacctta tgaagtcttc
     9421 tttgataaag tgttgcgctt gatttgacaa ttcaagacat aataaaaagc agatcaaatc
     9481 caaataaggg aaaaatgatc tactctggta ttatcaatta attggccaag ctattatgcc
     9541 gttttgctaa acgtctactt cttccagtat tgaccttgat aaaacaacaa tcaggatccc
     9601 gttttaatac tctatgaact gtgtcaatac taacatgtaa agttgcagca atatcagcta
     9661 atgtactccc atttaatctc atttgctttg caaatcgata acgccgataa gcatcaatat
     9721 tcttggaatc catagacaat aatacttttc ttaccatgta tttcctccaa aaattgaatt
     9781 ttaatgagcc atcatttctt gagcaatttc atgtttagac aatgaagctg gatagaaagt
     9841 aggccaatta tgcaattcat tatagagttt ttcttgactt tctccaccaa agaaaatatg
     9901 gaaatgctct gccttacttg gtgcaattcc atgatcacta aattgaatat atttaaaacg
     9961 accagcacct gcatcatcag tttcaaaatt aaaacgaaca ccacggtttc ctttttcata
    10021 attcaaaatt ttgtatccaa catatttgta tgtgtattga tgatgttcac cgttgactac
    10081 aaaatcaatg gtgttgtctt taatgttgat agtatcaata tctgtcttat agccagtagt
    10141 ataataatct ttgtactcgg cagctgtcat gtctttattg atttttgctt tgtaatcgaa
    10201 aacttcatcc aaaattccat cttttaacaa cggataaaca gattgccatt cgcctgtata
    10261 atcactcaat tcgcgatcct tcacatcggc atctttaaag tacccattag caactgtctt
    10321 ttcatccttc gcttcttttt ctggaactac ctcttcacca gcaaccatag ttgttttttc
    10381 taacgctttt agattgtctt ccattactga aacataatct tcaccattat ccatttgttc
    10441 ttttgtaaga ctttcaagag gattcagtac ttccaatttt atcccagctt cgttggccaa
    10501 agtttttgca attttatcat tagcattctt ttcaaagtaa atataattga tcttattttt
    10561 tttaacatac tcttttaatt cagctaatcg accagaagat ggctcttctt caggacttag
    10621 tccagcaata ggaacttgtt tcaatccata atccaaagct aaatatccaa aggctgcgtg
    10681 ttgcgtcaca aaactttttt gtttcgcttc tttaagacta gtggtatagt cagcatccaa
    10741 ccgtttcagt ttagtcaaat acttttcagc atttgtctca aatacttttg cttttttcgg
    10801 atacaattta actaactgat ccttgatatt tgaaacttcc ttaattgcca ttttgggtga
    10861 aacccacgta tgaggatcta gttcatgatg gtgatcttct tctccgtgat catgatcttc
    10921 ttcttcacta cctggcaata aaatcatgtc ttttgttcct tctactacat taggcccagc
    10981 tttcttccaa ctttctttag cttttggtac ccatgattcc atgttttcgt tatgatatac
    11041 aaaaacatca gcatcatgag cttttgccat atccttagct gagggctcat agtcatgagg
    11101 ttctgatccc gctggaacca ttaaatccac gttcgcttca tcgccgacga tgtttttggt
    11161 gaaatcatac attggataga atgttgttac aatttctaat tttccatctt tatcattcga
    11221 tacttttgca tcattagtgc tggagcaagc tcccaataat cctagagctg ctatcccaat
    11281 aagtcctaca ctgattttct tcattctttt tccttcctta attatgctaa tttcttcatt
    11341 ttatttcgtt tatgttcttt gataattttt aatgcccttt ttctagtttt aatattcggg
    11401 cttttaagtc gtcgatatgc actagatata tccgttttct ccattagaaa ttacccccaa
    11461 tcactactta tcattatttg ctttccgcca gtaatttatc aaaactctgt ttgatccttt
    11521 cttcatccaa catttttccg attagaataa tagtggtttg gtctttttgt cgagtggtgt
    11581 attgaaaatt aacctgttcg tttacctctt gcatggcaac tataaaatcc tgctcttgta
    11641 aagcaatcaa tcctttaaaa cgatacaggc tcccttggtt ggttaaaatc agccagtcaa
    11701 tccattggag taaaaaatct ttttttatgt cttgatctga agttaagaga attgatttaa
    11761 actcatgtac ttgatggtgt tgatgatagt atttgccatt atagtgattt tctgatgaat
    11821 cactttcaaa aactaaggga tgattaaatt ttttcaaatt ataaaaatcc tttttttgaa
    11881 tcgtttcact atgtgtgaac attcgaatat cggataaagg gttaatactt ttgatttctc
    11941 tctgtaattt ttttagtgca gataaattca agttttgttt tctagacaca aaaatgcgat
    12001 ctgccatgac aagttgctta agggcttgtg gttctctttc aataagttca aaactgtcac
    12061 tatcaataac agtcaataaa ctatcgatat atactcttcc tcttagttga ggcgctgtta
    12121 aaagtgtttg aatgattggt tggggatctg ctatacctgt agtttcaatg atgatttgtg
    12181 aaattggttg ttgatgttct tctattgttt ccagtaaaga aatcaatatt gctaataaat
    12241 cactgcgaag actgcaacac atacatccat tatttagttg taacacccgt tcctcgctat
    12301 gaactaataa tttgtgatca atcccaactt caccaaactc attttcaatt ataataattt
    12361 cttccctggg gtagggtgag acttgcaagg cttgattgat tagcgttgtt tttccagccc
    12421 ctaaaaaccc agaaacgatt gtaactggta tgcccatttt gtcacctttt taccacttag
    12481 ctatttcact tctttaaaaa ttgcccgtct gcgcaatttt ggcgaatact tttttaattc
    12541 taaccgttca gggttattcc gtttattttt gctggtgaga tacagacgtt ctccagtttc
    12601 gacacattcc aaaataatat tttgacgcat aaatcttcct ccttcaatac ttatcgatct
    12661 tcaagatatg cttgaatttg ttgtgcatct tcaaaagtta actcgccaga ttccaattgt
    12721 gaaactaaat tttctttcat atcaacaggt atctcccaat aaccatcgat acattgaaat
    12781 aactcctcgt catactcttc aaaaattgga tagattctta aaaaatcatc aaatgataag
    12841 ccttggtcct catagtaatc tttgactaat ccattttcaa ttgcctgttg ggtcggtaaa
    12901 cccgtttcag taataattcc tctctctacc atcgaacgat aaaaagtgca tttatctagc
    12961 gattgctggg tcgtttcaag ataatacttt aatccttctt caactaaagg tgggtaaata
    13021 atttccattt tgattccctc ctaaaagtta tatattaaac tattttgaag ctcctttaat
    13081 tactttcttt ccattatagt acccttttaa agatacatga tggctacgtc tataatcacc
    13141 attcgcttcg tcaaatgaaa tttctggttt tactacagtt tgatgagttc ttcttaaccg
    13201 tttcttcgcc ttagatgttt ttcttgctgg tactgccatg atatttcctc cttttaccaa
    13261 cttgcttttt ttactccagg aatcaaccct tgatgggcaa gttctctaaa cttaatacgg
    13321 gacataccga actttcgcat ataccctctt ggacgaccat ccgtctgatc acgaagcctc
    13381 agacgattcg gatttgaatc tcttggcaat ttagcgagag cggtgcgatc tcctgcggct
    13441 tttaattcct gacgtttatc tgcatacttt tcaatcatcg ccatttgttt ctttgcttta
    13501 gcaattttcg acttttttgc catatacctt tatactcctt ttattttgat ttagacacct
    13561 caaatcgtaa tcgttacgtt ttgacactga tactttacca acaagagttg ctcttgtcaa
    13621 caataaataa catgaaataa aactcatatg aatagataac tatttgaaaa cgaatttatc
    13681 ggtacataga gataatcaaa tcatttaaaa gaatatgcag tttaggctct gaaaaataag
    13741 aattcacttt tattagtcca atcaaacaca aataccgttt taagtagctt ttcctctact
    13801 taaaacggca atatgaaaga aactataact ttttattcaa tcttttatgt ttaactggtt
    13861 tatcgccaat tttttaaaac tttgattatt ccttatatta taagaataga cattaagtga
    13921 actaattcaa tcatactgat tctttcgtgt attcaaaatt agatgctgtt taataaaatt
    13981 attctttttg aaaaagaatt ataactatat cccaaaaatt gtaggttaat ttaaagccta
    14041 tttcatcatc gtgattgagc ttctttttca tagacgaatt tctcagatag tttagttttc
    14101 tttatgagat ttttgtatat ttctgacctt cgatacaact cattatgagt accttgatca
    14161 actagttttc cttgatccat cactacaatt ttatttacct tttcaataga cttcaagcga
    14221 tgcgatataa ttagtactgt cttatcttgt attaaacgat ttaaactttc ctgaatacgt
    14281 ttttcatttt ccgcatctaa actggcagta atttcatcta aaattaaaat tggcgcattt
    14341 ttcaaaaaag cccgtgctat ggataggcgt tgtcgctctc ctccagaaag tgaacttccg
    14401 ttttctccga ccaatgtatg ataaccgtca ggtagttttt caataaagtc ttcgcagtta
    14461 gctaaacgag ctgctttttt cacttcctca tctgacgctt gactatttcc aatacgtata
    14521 ttttccaaaa tacttgtatt aaacaaagtt acctcttgaa aaacaatagc gattttgcta
    14581 aacaaagaag ctggagatac acgtttaata tcatacccat caattaaaat acagccttca
    14641 tcataatcat acagtctaga cactaatttc aagatactag ttttcccgga accactagca
    14701 cctactaacg cagtcacttc tccttgttta gccgtaaaag agatatgatc taaaattggg
    14761 gtattgttat catatgagaa agagacatct cgcaactcaa tgtcaaaaga tttcagagga
    14821 ctatctgatc cctcttggat actggtttcc ttcatagctc taattcgctg tattttagga
    14881 gctaaataaa atatttcaag cactgcttct ttcatagaat cgaaggaatc ctttattttt
    14941 attgcggcta gtaagtaacc aacgacgtag agtatagtca cttcacccgt taacagtaag
    15001 tgaacaccta ctagaatgac tactgctaaa ctaacatatg agaaaataga ggataaggcc
    15061 atgactgaaa aagtacttaa ttctaccttt aaatgaatcc tttcactctc ttccattttt
    15121 ttgaaaagtc tgtcttgaac ttttttagat agattaaagc tattaatctc ttgctgcaat
    15181 tctatagttt cttgaaattc ttccgagttt tctctcaaag tatcgtaata tttagtattg
    15241 gctttcgttt gggatttctt tgataacaag attaagacaa aactaaataa cgttggcaaa
    15301 ataacagcta atcccatttt gacattacca accaaaagca tcactgaaat aaaagggaaa
    15361 aacagagcca taccgccggc tttaggtatt gcatgactca tcgcatgctc aataccttca
    15421 acgtcagaca tgatagtttg agataaatct gataaattat gttttgaaaa ataggataat
    15481 ggtaaatttg acaaatcgtc tgcaatttgc actcttaaat gcgcactttc tttataagta
    15541 ctattatata agttttcata ctccctatct aacaaccaat acatgaaaag caaagtaaca
    15601 aacgatacgg caaaataaag ccaacggggc tttgtatttt ctaaaactaa ttcgtctatc
    15661 agcatcatta taatgaatgc tggtaccata ttaatgcagt atacaaaaaa actagaaata
    15721 gaagctttag ttaaagcttc tgcgccctga tcacttaaag caaatttgtt tttataaaaa
    15781 cttttcattg tcaagcctcc aatcatttgc attctcataa ttagtgacca attgtttata
    15841 cacttgatgt ttagccatta attcattatg atttccacgt tctactattt tcccttctga
    15901 caagacaaga atttcatcta cagatttaat gctggataat cgatgagcta tcataataac
    15961 tgttttttct tttatcagat gttgaaaagc cttttgtagt tcatactcat tatctggatc
    16021 aatagatgca ctggcttcat ccataataac aatctttgca tcttttaaaa ttgctctggc
    16081 aatagctata cgttgttttt ctcctcctga cagataaact cctttactac caattaaggt
    16141 atgctctctt tcgggaaatt tttctaaaat cgattcgcaa ccggctaatc ttagcgcgtc
    16201 aaatacttta cttgctggcg cttgaggatt tgctatagaa acgttatcgt aaatactctg
    16261 attgaatagt ttcgtatctt gaaagacaaa agcaattgtg ttaataattg tgtcttttga
    16321 atagtgattt aaaggcttac caccaatttt aatctgtccc ttatccacat tgtagaaacc
    16381 tgaaattagt ttagctatcg tactctttcc gcttcctgat tttcctacta atgcataaat
    16441 tcttttttgt tctaaaacta agttgaaatt ttctaaaaca cactcttctt tgtatgaaaa
    16501 gctgacattt tcaaatgcaa tgtcacaatt tttaatctgt gtctcgttcc catattttag
    16561 ttggtcttgc ttcatttcta aataaaggga gtctagtgtt tcgactgcat atcttgcttc
    16621 aaacaagtgc atacttacat acattattct catgaaagaa acaaaaataa ttccacttaa
    16681 aaaaaacaac atcaacaagt caacagctaa tatcttggga gtggtaagag aagttataaa
    16741 aaaggttata ggaactatca aaatgcaaac tatgccaaaa aatagccatt gaaaaagaac
    16801 aaaaggtgtt ttcccactca aagaatactt atatgcaaac ttagcataat cgttaattgc
    16861 tttattcaag gctttaaatg atgttacttt agcaccaaat atctttataa cttgaattcc
    16921 gcggatatat tctaccgttt cagagcttaa cacatctaac gattcttgat atttttgaat
    16981 aaaatttgta ttctctgtca ttttctttaa caagaataca ccaattacta acatggcgat
    17041 tagaaccaat ccaattttaa agttaatgaa aaagcctaag gcaactgata aaacaggtgt
    17101 tactatggct tgagcactat ctggaatcaa gtgagcaatt gccatatgtg ttttagccgc
    17161 gttgtcatca attgtctttc gaatatatcc cgaagaattt aaatcaaaaa aacgaaaact
    17221 tgcttctgtt aaaccgctaa ttcccttttt tctcaaatta gtctctaagc gaaacccaag
    17281 gatatgagaa aataagccag aaaaaatata aaataaagct cctaaagtta accaagcaac
    17341 agtttgaacc gcataactct tagctaaata ttcatctcct acaataatta gagactgaag
    17401 aaatttgtaa atactgtaat atccatagac tgttaatacg acagaaaaat cagaaaataa
    17461 agtggctaac catccgtagt atttcatttt agggacataa ctaaataatt ttttgtatac
    17521 tttcattttt tcctcccccg cattcaattt cttctcttat tcgtttacaa ctgttaatgc
    17581 tttccgtaat agcgtaaatt agagatgtac aaacagataa aaggtaaact acgttctatt
    17641 ttttgtattt ttttaagact tttcttccaa tcaatacacc aatcatagat aaacttgcta
    17701 caactaacac tgaaatgatt ccccatatac ctaccgcata gtggatcatt gcatccattg
    17761 ttgcagcaga ttgtccttta tctatccaat cttgacgaaa acgatctgta aagaaccata
    17821 taggaatcca ctgtccggca gcactgccta attgcattag agcccaagac gcaacttgag
    17881 gaattgctcg atcatatcca aatacagata gaataatatc agctaagatc gccatactaa
    17941 tcgaactgat aaaccaaggt aagtacgccc cgcccattaa cgtaaaaaat aacaataaaa
    18001 caattgtgta aatagtaaaa attccttttc tagggtagtt atagctaata taaacaaata
    18061 tgattccaga taataatcca aaaatcccgg gggatatgct gtgaccaaac gccccaccaa
    18121 tactactaac cattattgaa aaaaagtaaa ttactaggga aataactgta gctaaaccaa
    18181 taaaaatata atcttttgtt ttcatatata ttctcctcaa ttctatttcg ttatgtcatt
    18241 aaaaatctgt tctatcaaag ttgaatcttc tactctaagt tttatatctt tttttattcc
    18301 accatttttt aaataaataa ttctattgca tgttttataa agaaattccg gatcatgagt
    18361 agctataact actgcaccct tttcttttaa gtctttaata aggtcagcaa tcctttccat
    18421 attaatataa tccaacccac ttgtaggttc atcaaataga aataaattag tttttgacaa
    18481 tgaagctata gaaaccaata atctttgttt ttctccaccg gataaatcaa acggtaattg
    18541 atctttcatt ttataaagtt ccattttttt taaaattttt tcttgctgat ctttactaac
    18601 tatttcattc cccagggcta actcgctcct cactgattct gtgaaaaatt ggtaatccat
    18661 ttcttgcatt actaaaaacg gcgatgacaa atttttttta ttttcgatta tctttccttt
    18721 ggtagggcga ataatcttca tgagtattct tagtaaggtt gttttcccca caccgttttt
    18781 ccctaccaaa ccaataacat ctccaacttt gacatcaaaa tttatgtctt ttagaatatt
    18841 ttcataagta atttcttcaa cttttaatac atctgcactt accttttcga tatagggaac
    18901 ttcaatcgaa ctattaaaaa tgtcaaattt ccttaatgcg ttattgtttt cagtttttaa
    18961 caactgaata gttgtagttt ttacagttct atttttaaca aatagaactt gatcaattaa
    19021 ttctttcaaa tagtaaaaac gatgttcagc tataacaata gtaaatcctt tattttttaa
    19081 atcacaaagt aagtcagcaa gtttcttagt cgctttgaag tccaaatttg aagacggttc
    19141 atccaatata attaatttag agtttagcga taaactacat ccaatagaaa ttttctgccg
    19201 ttcaccactt gatagcgaaa aaatgttttt atctaatata tttgaaagat ctaataattc
    19261 agctaattca ttgattcttt tatccatatg ctcttttgta aatccaaagt tttccatcga
    19321 aaatactaac tcactcgttg tatttgttgt aaagaattgt cctctaggat cttgacttac
    19381 gtagccaata ttttttgata tactttcttg tgttaaggat tgtagcgagt tattttcaaa
    19441 taaaatttcc ccaaccaatt ttccgtcata aagtcttgga ataagtccat tcattaactt
    19501 taatagtgtg gatttcccac tcccagaaga accagtaatc aatgtaagac tgcctttttt
    19561 tattgaaaaa ttaaggtcaa caagcgcttg ttccttaaca tccttatatg aaaaagaaac
    19621 attgttaaat tcaaacaatt ctttcacctc aaatcaaaat acttaagaaa aaaatagtaa
    19681 cggaaaacag gatgatatag tctaataagc tcatgtttgt tttatagtaa gaacttcttt
    19741 tcacaggaga ttctatcccc tttgttattg cattagcggt catttcttca gcaatcatag
    19801 ttgcacgtat aagaacggga actaacagaa attccaaata ttgcagaggc tgaaaaaaag
    19861 acaagcgaat gtttctcatt tttaaagatt ctttaatcat tcttatttca gaacgataag
    19921 tcggaaagaa tctgatcact actgtaatac ttaacattat ttttttcggt aaatgtattt
    19981 tttctaaaga ggataataat tcattgctag tatagacact aaccaacaac catgagatca
    20041 ttacgaccgg caacattcga aatacaatat ataaggatgt cgcaaaaaat atagtaaaaa
    20101 actctatctt gatagcatca ataattttca ttactaaaaa cagaactgaa taaatcaaga
    20161 tgaaataaat acatgtcttt attttacgaa acatcaatac taaaactgta gcaataatga
    20221 aacaccccac ttgaaatata tttccctttc ctaaaaaaat aatgaccgga aaaaaaatat
    20281 ttaaagtaat caaggttaac ggattgattt ttgacactct ttcacctcca aaaaataaga
    20341 tcgcactgtt atcttaagct gataaaaatg caccgttatt cagataacag tgcgatctta
    20401 tcaaaaagca taactgagaa caattctcaa tgcaagcttt ttttaattaa ctcagtaatt
    20461 caatccaccc aggaacagaa aattgataca atcttctggt taatagcata gtcttttctt
    20521 ttgaatagct atgcttcaat atatcataga atgtagcgta gaatgagtaa atgtagaagt
    20581 ggatttcttc ttcattaaag actaaatttt gattgatcat tccgatagtc tttaacttat
    20641 ctagacaaca gactgtcttt ttcgtcacaa atgatgtaat tttttcaaca atatcttgat
    20701 atttggttcc agctgattgg aataaaatca aatcgaatat acgtttattc tcaaaaatat
    20761 aattaataaa tggatctaat tcattgaagt tctctctcca acttttctct atatctatat
    20821 tttctaagtt taagaggtat ttggtaaact cttcattata catattaata agcgcattaa
    20881 tatgcggctg aataatttct tcaaataacg cttccttaga agtaaaatgt ttataaaaag
    20941 cacccgtagt tacgcctgcg gtcaggcaca gttgccttat cttagtttgc tgaaatcctt
    21001 ctttttcaaa atggcttagt ccactttcta ttaacttttg gtgagttata atataatctc
    21061 tggtttctat gggtacttcc tcctaataag atgaattaac tttattatct tacacaggac
    21121 ttgaagtttc aatcgttaac gtttattact gaactcattc cttagagcta aactaatgag
    21181 aaagagcaga ataactgata caaaaagcaa tcctacaaga attaatagac tcatctaaat
    21241 cattcacctt ttctaaaata atccgagaaa gatttaaaaa aattatatcc agctattagg
    21301 ataagtccta tcataatcac tccaatagcc attttcttat cctccctaaa aataaagtct
    21361 tttacttaaa accttttttg taatcgtcaa taaatttttt ccctttatca gttaattgaa
    21421 atcctatatc taaatagtcc tcatatctaa gtttagccag catctcactt acagatgctg
    21481 gactaacact tagaactttt gctaaatcat tattttttaa tttctttttt ctttttgata
    21541 attcctgaat tgctagtaaa taaattagta tagtagtcgt tttaatttgt accataccta
    21601 ccctccaaat tatttcgaaa ggccttcagc aattttatcc aggttccatt tcatcatcgc
    21661 atagtaacta tcaccatctt gtcctttttc tgcaattgaa tcagtaaaaa tcgttgaata
    21721 gataggaata ttggtatctt ttgatactgt tttcattggt ctatcatcca cactgctttc
    21781 tacgaataag gagggaactt ttgttgtgcg taatttttca actaagtgtt ttatttgatc
    21841 tggtgttcct tcttcttcag tgttgatttc ccaaatgtaa gcagaaggca cattatacgc
    21901 tttcgagaaa tatttaaagc atccttcact tgtaacaatc atttttttat cattcggaat
    21961 tgaagcaaat ttagatttag cttctttgtc tagagaatcc aatttttcaa tatacttatc
    22021 tagattttct ttatagaatt ttttattatc aggatctttt tccgctaact gtttttcaat
    22081 atttttagcg taaataatac cgttttctaa atttaaccaa gcatgaggat cttccttccc
    22141 tttctcactc tgaccctcta agtaaataac atctatgcca tcacttgctg caaaatagtc
    22201 tttgttttcc tctttgttcg catttttaac taattttgta aaccaagcat ttcctccagt
    22261 ttccaagtta acaccgttat aaaaaatcaa atctgctttt gaagtttttt gaacatcttc
    22321 aggcaaaggt tcatattcgt ggggatcttt cccaataggt acgatactgt gtaaatcaat
    22381 tttatctttt gctatatttt cggtaatatc tgctaaaatc gaattagtaa ctactacttt
    22441 taatttttcg ttcgaagcca ctttatcttt gtctttacta tttattgaac atgccccgaa
    22501 tataaaaaga gcaatcaaaa tccccagact tcccagtact gctttccatt ttctcatcat
    22561 aacgatctct ccttctttct taaaaatttt tgttttggtg agattagaaa actaattaca
    22621 aataagaatg ccgctgttaa aacaatactt gatcctgctg ctatgttaaa actataacca
    22681 ataaacaatc caagcaatga tgaacttgct ccgactgttg cagaaataaa tatcatagtt
    22741 ttcaagctat ttgcatataa atatgctgta gctgctggtg taattaacat tgcaacaatt
    22801 aatatagttc ccacactttg catagctgtt actgctacta aagttaatag aaccatcaat
    22861 agataatgat aaaaactgac attcatccct attgcttttg ccattaatgg atcaaaagaa
    22921 gtgattaata attctttaaa aaatagaact actataacca acactaaaac cgaaacgcca
    22981 attgtaatcc acttatcaat atcttgtaca gctaaaatat ttccaaataa aatatgaaat
    23041 aaatccgttg agctatttgc aactcctata aggataactc ctagtgctaa aaaagaactg
    23101 aaagtaatac caattgctgt atctcctttt attacactat tgctttttat aaaagtaata
    23161 atgatagaag ctaatagacc aaatacaatc gcaccaataa aaaaattaat acctaaaata
    23221 taagaaattg ctactcctgg caaaacagca tgagaaatag catcacccat aagagacatt
    23281 cctcttaaaa taataaaaca acctactgtt ccagaaacaa tccctataac tacagatgta
    23341 attagagcat tctgtaaaaa gtgaaagtca tacagaccat taataaaatt ttgaagcata
    23401 ttattccccc tctccaataa atatagtatc tccataggct ttttttaaat tttcttcatt
    23461 aaatacagat tctacacttc cgtgagcaat tagatttcga ttcaaaagaa taatattatc
    23521 aaaatacttc tttaccttgc ttaaatcatg atgcacaatt agcactgttt ttccctgatg
    23581 tttcaatttt tttaacgtat ccataattat tcgttcacta actaagtcta tccctacaaa
    23641 tggttcatct aaaaatatga aatccgcatt ttgagcaaga catcttgcta aaagtacacg
    23701 ttgaaattgt cctccagata attctcctat ttgatgatta gaatattttc ccatatcgac
    23761 cttttccaaa gcctttgaaa ctctttgcca ttctgcattt ttaattcttt gaaaaacttt
    23821 cattccggca tatgttccca tagatacaca ttcttttact tttattggaa aagtaaaatc
    23881 aatatcagct ttttgctcta catatgcaat cttcaccagt tttttattga tatcttcatt
    23941 attaatggag acctctccct gatgagggat aatatttaac attgctttaa gcaatgtgga
    24001 ttttccagca ccatttggac caataatacc tgttaaagca ccttcttgta tttttaaaga
    24061 aatctcgttc aatgctaaaa aatcgttata acaaacatta agctttttca cttctaacat
    24121 aactttctcc ttctaaatga taatgattat cacgatcata tggtatacaa aaattatatt
    24181 ttagtcaacc ctaaatttta tagtttagat ttttttctgt tgctgaagat tagaatgaca
    24241 aaactatttg aaactacgcg tatagtaagt agctttcaaa atatataaaa aaggagcgtt
    24301 ctcaaatgag aacatgctcc taaaactact ttattggcgt atggaaaaat tatacttgaa
    24361 gtggatagcg ggttgaataa gttgataagc atcaaaacat ttataaaaat tattcaagac
    24421 tatgtctgtt ccatatacaa atatgaaaat cagtaaactc catttaactt ttttcgtagt
    24481 gtgtcttttt atacatgttt atcgttatta atagtgaata ggaaaaaaac tatttttgat
    24541 cattgacaat taaatacaat ttttgaataa cgatccctgc tattcgagct agaaactcaa
    24601 gtacgccatg acctgattag cgacaaatac ttagagattt ctttttgttc tgggaaaaca
    24661 aaatgccatg acaatagcag caaataatga tacttccgta aggctcgccg taaactgggg
    24721 agaggtgaaa ttcctatgtg cttacccaaa gcaattcaaa aatttcataa ctactatttt
    24781 aggagatgat tttatagaat ccagagtcta cctgaataaa aaacaaacct gtgcatttct
    24841 aggaatcgat aataatactc tagataagtg gattcgtata tataatttcc cagtaataag
    24901 agttggtggt gtagttcgct ttgacgtaga agatattaaa gactttatga atacatttaa
    24961 aataacttga aattttcttc tcgccgcata tactaaaatt agtgaaatat actgccttac
    25021 tttttttaag gagtgaggat tttgcctaca aagctttcaa atgggaaata taaaactaat
    25081 ctgagatatc caaaaaggtt taaagaaata acaggaattg catcagaaaa gtatcaaaaa
    25141 acatttccaa ataggcaatt ggcgattaaa gccgaaaatg atatgaagaa gaaaatagaa
    25201 aaagttttga gagaggagaa tgcaaactca ttagaattaa aaggaaaaat aacgtttaaa
    25261 aaattttacg aatctaaatg gcttcctaga tatgaattag gtcaaacaat tagatcaaac
    25321 aggcctccta gtgatataac cattagtaat acaaaagata tatttcggtt gcatatttta
    25381 cctatgtttg gtgaatacgc aatgaattat ctaaatatca atactgagat aatatcagat
    25441 gaattaacca aaaaatcgaa agaatatgca aatataaaaa tcataaaagg atatgttcgt
    25501 tccatgttcg atattgcaga aatactaaat tatatcgaat ttaatcgaac tactaaaatt
    25561 attcaaagta tcactgcacc taaaaaaaat gctttagaag aaaaaagaat acaagaaggt
    25621 aagcaagcac tatcatcaaa agaacttact aattggatag aagcagtaaa tgatgatttt
    25681 aataatcatt tacttacttt tcatgattac acacttttta tgattaccct gtatcttggt
    25741 gatagaaaaa gtgagactta cgctttgcaa tggaaatata ttgattttga aaaacaaacg
    25801 gtccgtctta aacatacttt agataaatat caaagaaaaa agtttacaaa aggtcgaaaa
    25861 gataccgtca ttcaagtacc agaagttgta atgacattgc taagtgaatg gaaatcggta
    25921 caagctgatc aattgttgaa attaaaaatt aagcaaacgt tagatcagta tctctttact
    25981 tatactaaac catctggaga agtaaattgt cctgttcatg ccgattacct aaactatcga
    26041 atcaattcaa ttaaaagaag gcatcctgac ttagttcatt tatctccaca caaactccgt
    26101 catacttatg caactatagc tagacaaggt ggagcagata tgaatcaaat ttcaaatgct
    26161 ttaacacact cagatatttc tacaacaaag atatatgtga acacaccaga tatagttgat
    26221 aaggctgttt ttgaagcttt tcagagagga ttgaataagt gtgattgata tgtgttctta
    26281 aatgtgttct taaaaacaaa agaagcactt tccaaataat tgaaaagtgc cagaaacgtt
    26341 gatatataaa ggatattaac gttttgagaa ttgtgaagct ttacgtgctt tcttaagacc
    26401 tggttaaaca aacttttcat ttataatgtt ttacagagat atatgtcgta tgaaattaat
    26461 gttctcttgt tcatgaagtt ttacagaatt gtatagggtt atctgttgtc attacctcaa
    26521 atcattacca caacttggcg agttggctga ttgaagaagt actctgtttt actctatctt
    26581 actctgcttt actctatctt actctgcttt actctagctt actctgcttt actctagctt
    26641 actctatctt actctatctt actctgcttt actctatctt actctgcttt actctagctt
    26701 actctgcttt actctatctt acctgcttta ctctatctta cctgctttac tctatcttac
    26761 tctgctttac tctatcttac tctgctttac tctatcttac tctgctttac tctatcttac
    26821 tctatcttac tctgtcttac tctatcttac tctgtcttac tctatcttac tctgttttac
    26881 tctatttaaa gaatagtatt gagtcggatc tttggtacta gtaccatgcc actgaattat
    26941 ttttttcctt aacatttcct ttaatacctt acggctatat ccgacccctt tttttaatac
    27001 ttctgaagct tcttttaccg aaattttttc gttattaaat aaatgtgaaa caatcatctt
    27061 ctcagaagta gacaaagagt ctacttcaaa ttctccaaga taatcatcta gtctgtctct
    27121 ctctcttaaa tgtctagagg ttatactatt ttctaagact aataaaaccg aattattatt
    27181 tggctcacta tatttaggtt catttaaaaa tagtaattgc atttcgtcat atattcgatt
    27241 cacaccttca ttaagttcct taacccatcc gaattcagat aatgtcctag cgattctggg
    27301 attcctagca tacctagttc ggcgcatatt ttgtaaagtg actatattag gtaaagctcc
    27361 cgggctaaaa atttctaacc tatcatcata catattaatt ctaacgtaat cccctttata
    27421 agaatagtct ctatgcgtta aagcattgac tataccttca aaccatgcaa attcaggata
    27481 ttcaggtatg atactaaact ttccatcatc atttaaatac tgaaattctc ttagttgcgt
    27541 ttttacatcc ctagttatag attcgattag ctttggaatt gcaccttcat agtcaaattc
    27601 tttaactata tttaatctcc gtccagtttc attacgctta ccatcatatc tcaaaaaacg
    27661 aattctagaa ttaggtaagg ctagaaatgt attcttacca aatagaagca tgccagcatt
    27721 tgtcaagtga ccatttctca ttaaccctct tccagtgagt atggtttctg tggatatcgc
    27781 ttcagctttt tttaattttt tatatgaatc catgagagat tcatcaatat catcaagagt
    27841 actgtctaaa atttctatat cttcaaacat tctctgtcct ttgtcgtatt ctagtttgga
    27901 tatttggtca tgagtttgat gaacactttt atccccaatt ctcaagaaac aatcaccgtt
    27961 cgaattaaaa atcacatggc ttatgctagg ttcaacgtct ataatgaata atatatcgtc
    28021 ttctcctcta gcattcttaa tactcttcat ttctttttta aaagttggat tgggttttgt
    28081 cattgaattt atagctagta catattcatc tggatcgatc gcaccttgaa atttaaaccc
    28141 agaaatagtc ccatcatctt ctataccgat taccagctta cctccatcgg catttgcaaa
    28201 cgctactatg tgttttataa tatctctagg cttaatccgt gcactttttc tatcaaaata
    28261 ctgatcttct ttttcactta taaacttttg aatctcataa tccatttaaa atttcccttc
    28321 ttaaattttt ttattataga gccgtatatt caatttccac aaaaaaataa tctaaaacaa
    28381 aacagacacc ttcattttga tatgttctcc cacatatgaa tcggtcgcta tacagcatta
    28441 catatagtaa ttattcatac tgcgaaataa atagctccaa atctttagct ggcgtagtta
    28501 agcttaaatt cgaaatgaaa gtttcattga ctattccact ttcatcaaat cccttcttca
    28561 accaatcaga gttccacaac gtaaatcctt taggattaga aactttctta cataattttg
    28621 cactatagga tttctctctt gaatgaatta aagaaagtct ttgtaaccaa atttcaacta
    28681 tatccgtatt aggagtatta acaaattttc ttaagatttt atccaagtat aagttgattt
    28741 cttctacagc aataaactca aaaagcttac ctaaaatcac aatacaagcc tccaaagttc
    28801 taggattctt ttgcattata ttaacaagaa tactaatcaa ttggtagata tcatctggtc
    28861 ttttgtttaa agtagaaact ctatgtgtat agacttcact tagcgcttta cttaaactcc
    28921 cgcaatttgg atatttgtct cctaaaagct ttacctgtag caaatgcttt tgaaggctaa
    28981 gcttaaactt ccacttatta ttacttttct ctgtaaaact tgcatgttta agatcccagt
    29041 aaattttatc aggcttaatt gcatctaaaa ttatattatc cgataagaat gttttatttg
    29101 aatttagctt caaatttaga tccgataata cttcagataa caatctgata atcacttcag
    29161 cttgatcttt tcgaaccgaa aaaattctat aatcatctct gtaacgaagt attttgaact
    29221 ctttaatctc tgttttttct atcttgttca gtaacatttt atcagcatac ccaagtacta
    29281 tttcagctac aaaatccatc aatacatttc cttgaggtat accgttcgtt tgtccatttt
    29341 gtaaatatcg tattttagaa tctattaagt ttccaacgcc ttgagtatct tttctatgtg
    29401 tcttagccca ttcttttgaa tgtactgccc acgggatagt atgtgtgtac attgagctat
    29461 aacaatcggt aatatctgaa tgaatgcagt agtcatactc caaagcataa ctaatctgtg
    29521 cttgttcaag gttctcccac caatttaaaa tagtttccgc agtatcgctc tttgaagaaa
    29581 tagattccac aggaagtgat atacattcaa ttcgcttgtc ggcttggaat tcttcaaact
    29641 tatttttgat gtgattccaa ttatttttct gtgtaatccc gtttactaag tctacatata
    29701 ctaatggatg taatatttga aggggtctcc aagcataatt accatcttta ttagctaata
    29761 ttcgatgatt aacatcaact gcctcagaga gcgatctctt atgtctaact agttcagtaa
    29821 atgatttgtt ttttaataaa tccactgctt tctcaatgcc tactgataaa tcaatataat
    29881 tgggcaacga tgtactaaaa aaacttgatg tttttaaaaa gaattgcttt gcttcttgat
    29941 gattcatctc taaaatactt tttctagtcc tagtcaaatt caaaatctcc tagatcaatt
    30001 aagttgtaat gtaagaggat accctaacgt tacatatctc attcattatt ataccagtat
    30061 ttcttcatga cacataaggg tgtaacataa taattttaaa cgaaatgact acaagtagtc
    30121 attgaagtaa gtcttcataa gatacctgta ggatatccct aattgctctc aattgatcta
    30181 acttaatgtg ttgccggcca ccttcaattt taaccaatgt ttccctagtt atagcaattt
    30241 tatgaagctg taggtctcta atcagctcgg tttgaccaat tcctttttct aatcggattc
    30301 gtctaatatt gctaccgatt acattttctt tatcaataat tttttcctct ttcaagaata
    30361 gcacaccttt tggactaaaa ttagtccttt ttcttattaa tcttaaagat tcggtatgct
    30421 acaatgggac tagtattagt ccacattcaa ttttaaggag gaattttttt gaagaaattt
    30481 gcaatcattc taacctgcgc tttactcatc ggaactataa gcgggtgtac cacttctgaa
    30541 acaagttcta caagtacgga aactagtaca acaacctcag aaaagaatta cccaatacat
    30601 ttttttccgg ttccagatgg atttgaagct tattatcatg ataaaaaact agatgtccct
    30661 ttatcagaaa ctgaatctac tgaaaagatt ttgccaattg aaattgaaag aaatcaagac
    30721 gatataaaac taaaagctga tcttccctta ctgaacagca cacaaattga tagacatgaa
    30781 aatattaaag ttaatattga aaaaggagcg ttagcaaaac tttatactga aaaagttgaa
    30841 caatttttta agtctggtgc caataaagac ttttcaaaaa taagcgatta ttcggagaac
    30901 ttttttaatg aaacccaaga tgaaatcatg aactcaactt ttatggctga agatatgtac
    30961 aatatgacat taaaaaaaat aaaagcttac gaccatccgt taaatctgac actaaataat
    31021 ggactgcttt cttttgtatt agcaggttac gttgactatg aatattcacc agattatttg
    31081 gagaaacctc ttcaacacga gaacaatgat attaatttta gatttgtcta cgagtcaaaa
    31141 agtaaaacat ggttagttga tcaattaagc acgataaaca caagcttcca tgaattacct
    31201 aaacctgaaa atgaagttga gatggtcatt aaaatcttct aaaaaagaag cgttgaagga
    31261 gaaatattcc tttcaacgct cttttttata tgcttagaaa cataaataaa ttgtatactt
    31321 tctttttagc ccctattact tttcacgaaa aatatctttt tttcgacgct agcgtttctc
    31381 tacttctaat actgtacaca gtttttgtat tattgaaaaa ttactcatta tttagcatta
    31441 atccacatcg ttttatcaat cgaccttcat actaaactac tttaaagtca tcttccttct
    31501 cgtttttcat taaatcagac acataagccc atgtacccgt tcgttgtaaa taaagttctt
    31561 cttgtaacaa ctcccatttt ctcttagaaa tcataatgac gccatcgttc aatccatttt
    31621 tagaatccct agtaatttct atttcagaat ttgaatgaac tacttcttgc aacactttac
    31681 ctatattttc tttgaagttt gttggagtaa tagtatccaa aatgaacacc tctcttctct
    31741 atacctctat tatgaagcgc ccatcaaata aagcaagcgt tgaggaataa ttctatcaac
    31801 acttgcttta ttaagctttc attttgtagt ttgactaaaa ccaataatct tatttctaaa
    31861 ctctcgaaaa acttcttgtg gctgataata gtctgcatct atttcaaatg tttctgagaa
    31921 taattcattg aatttttcta ctgaaataat gattttacca ttcttctctc gactgttttc
    31981 tattatttct gcttctaatt caaataaatc tagtgacgaa ttaaaatcat aaatcctgtc
    32041 atattgaaca aaaaaatcaa gaaaaagttg ctcaaactct ttcttattta tcactagtgt
    32101 ttcaagcaga tcaactttat tttcttcagt cattcttcca atttcctcac tttcgttttc
    32161 aaaaatcaca aaaatgatat taacttaaaa gccactaaca aaataagact tacaaattaa
    32221 agggtaatcc aacaaaataa ccattcgctc tacgtactac gatttggtag tcctgccttt
    32281 caatcggtaa ttcataatag taatttactg tttctgattt accactttca atatactcag
    32341 gattatccaa tatcatagca tactcataaa gctcttcacc atccttattt tcaatcgacc
    32401 attgttgcgg acgtatcgga ttttctgtat catttttcat tgtataggtc acttgtaata
    32461 cacgatcatg ctgtgcaaat tcatttcttt tttcggtcag ttcaatattt ttaaatgtta
    32521 gttcaacccc atctgcctga taagtttcac ctatttttaa atcttttgtt acaattttta
    32581 ttggcttttc ttctggaaaa tacctggctt taattgttag ataacttcca aaaagaatca
    32641 atcctagtag cacaaaaaaa attcctttaa cgagccactg aaacgggaag taaactttaa
    32701 acatcttttt tctcctccgt tttgtatttg gtttttagag aacacgataa cttttgatca
    32761 ataccatcca actttttcat tatacttgat tctagttctg aaattgtttg ttcaagttta
    32821 atgctttcag gatcactaaa ttttttattt gattgactag ccaacattgg taaatttgaa
    32881 accatcacac ggaacatatt tgctttcgtt ccaagagttc ctttattctt ctcataaaag
    32941 ctgtcaaaca atttttttgt ttcctttgaa caatatactt taatatacgg atcagacatt
    33001 cttttccctc tccctgttta cttaaaaatc catatcatat tgattttgtt gtttttgata
    33061 atcaattcct cttgctgttt cttcatactc tctccgagct ttttcaatcg taccatcatc
    33121 aattgcacga ttaaataaat aaagaacacg ttttgtttct tgaatataac gcttcttaaa
    33181 attacgtttt aaagcgggtt cagtatcttg aatgttaaat tggtcataat cagttgataa
    33241 actctctgcg atatcataaa caactttttt atacaccaaa tttacacatt tcttcttata
    33301 ttttaaaggt tcctcttcca ctgcaaatcc aaagaattgg tttttattct caccaaaaac
    33361 atccaataaa ttttctattc tgtcctctat ttcaaattta tatttatcat aaaattcttc
    33421 ataatctttt gatgatctaa gaaatggtat attctcatta tctaattcaa agcgttgcgc
    33481 tcgttcttgc caattaaatc tactatccgc tctaccattt aacgatttac caagatgtcg
    33541 aatagcaatt tcagtgagta cctctttaga ttgaatttgc tccgcttttt tattttctgt
    33601 gaacaaatca tcaagataat tcatatcata gttttgccct aaacgctttc cgccaatttt
    33661 taagattaac tcgccttcag aatctaagag tttgtaccca atacgctgat ttttggcaaa
    33721 ccggtaagtc tcaatagaat ggtttttctt caattccgca tgaaaatcat cataattttt
    33781 cgcatactga gcaacttcag aaacagctag ttttattttt tctcgatttg aaatcttatt
    33841 ttcagttcta aattcacgtt ctttccaatt ttcacgatct gcaactaaat gattatactt
    33901 atacatatca agtgggttaa ttccattatc aataagtata ttatcattcc aagcctgcaa
    33961 aactcgaata tcattctttc gaatatccat tttctttcct gttagctgat cgtttggcga
    34021 aataccaaag tgattgtgaa catgcccttt gtctgtgtgt gtgacaacca aaattgactg
    34081 gttaggaaac attttttctg cccacttaac acccaactca tgtgcttttt cagcggaaat
    34141 atcttctagt ggatcaaagc tttgtgtaaa atgccaaagc tttattttcc ctttatcacc
    34201 aaaaatttca ttggttcgtt taaattcctc aatagcattt aaatcattcg atacgccaat
    34261 tcctgtcacg agttcagaat cttcttgttt atttaacata tatgaaattg tattatgaat
    34321 actcctactt tttgaagcaa tttttataat cgagcccata acttattcaa ctctttttcc
    34381 aagcgattca atggatcgct tattgatttt atttgtatca ttaagtcatt tttttcagca
    34441 tatagccgct ttaatcgctc ttgcttagtt gtaaaagata agtaaacact ctgatgttct
    34501 tctttttgta tctcggtatc ttttttattt aactgaacac gcaaataatt tgctgttttc
    34561 actaattgat tcaaatttct tcctattgct agtaaatgaa aattaatttc tttatattgt
    34621 cgatcggtat attttagact tttccctgcg ttgtctactg cgattttctt cacgtacatt
    34681 ggaacagata aaccaaaaat gtctgctgtt ttttctagct cttggtactg ataatcgtct
    34741 actcgaaact ttatcggcct attttgtcgt cgactatctt cattacgttt atatcgcttt
    34801 cgcctttctt ctaatggtag tttactgaca tcaattgcca tgcgcacttc tccttttcaa
    34861 tattattttt aagttcaaaa gaagcaagcg aggggaaagg gaacccttcc ccgcttgtcg
    34921 agggagtaaa ctccctacga gcaccctcat gctccgcatt ttatcgagat tagatagccg
    34981 ataaatcagc tacctaacac tttcttcttg cgcctcttct cgatagaaaa ttcgatacgc
    35041 tgtctctcct tttcttctca aaaattgttg gaatttcgtt tccatcaatt gatcgcttgc
    35101 aagaaattcg tgtactaggg taaattcgct attcgcgaaa tttaccgcct tttgccattt
    35161 ttcttgagta cctttttgat taatttcaaa agtttcttca aactctttta ctgatgaaat
    35221 tcctgttttt tcatagacat actttcccag ttcgggataa agttttctct ccaactcggc
    35281 gagttctttt ttcaaatctg caattgactt ttgttttttc cttgccattt ttcatgctcc
    35341 tttttgtatg tgactaagtt cattcataag ctcatttttc atcattaatt cttcttgaat
    35401 catcagttca atataatttg tgaccgtgat tttttcattt gttgctttct ttactgattc
    35461 acataattcg tcaagttcta agaaatcatg tgtactaatc tgtagaatta attgcatgac
    35521 aatcacctct ttatttttta aatagactat caaacagcgg atttggttta tcagaaatat
    35581 cctgaaacag tggattattt tcataagtaa atcgttgacg tttcttctcc ttcacttctt
    35641 gttctacaat cactttttcg ttaggtcttt cttttcgttc ctcgacaata tttatttttt
    35701 gcgtcttatc tccctgactt gcttcagctc ttgtttcacg tacttctacc gtttttggtt
    35761 gatttggcgc actactttgt acattttctc gtacgtctac tgttcgattt ccactttgac
    35821 tacttgtagt atcctgtaag tttaatcgaa catctaccgt tcttgtttga cctgtactgc
    35881 tactttgcac attctctctg acatccactg ttcgatttcc actttgacta cttgtagtat
    35941 tatgcaagtt ttctcgaaca tctactgagc gcctatcttg actacttgta gaattttgta
    36001 gattttcttt aaccgatttt tctaatccgg tatttgaatt tttagcttct tggattcttt
    36061 ctttggtcaa cgcttctttt tcgtccatat tagctcctgt acgcccttct acacgtttcc
    36121 ttaacatttc ctcacgattc attgcttcag gcgtgtattt tgcttcctgt cgcttctgat
    36181 taattaattc ttcagcagac ttagcttgac cgtgcatagc atttttacgt tcttcaatat
    36241 cttgttgaac tttttgctga attgcacttg cataattagt atttgattca gcaatatttt
    36301 tcattgcttc acgcatacgt tcagaactag acataattct atcggcattc tcaatcttag
    36361 ccccatcttt tctatccgaa agacgtattg gcatagaatc agcatatttt ccagtttcat
    36421 cttctttgtt tttagctact ataggtttgc tatttttatt aatagcggac acggtaccat
    36481 catctaaacc ttctttgaat ttattcttgg tatcattagc catatcacgc atactcttaa
    36541 atggttttgt tgctctttca ctagccattg tagctccatc cgaagctaag cctgataatc
    36601 cacgttcacg agcataccca agcgttttcc ccgttttatt agctttttga gaaagtgatt
    36661 gaccaaagtt gcgttcaggt tttcgttctt ccccttccgt ttgatcgttt ccaccactat
    36721 ttttcccacc tttagatcgg ttcatgccac ctgttccttt acgaaacagc attgcaccca
    36781 ttccaaaagc agaagcaagt tgcccatagc cttctttgag tccaatatcc acaccaaagt
    36841 aacgcatgac tgttccactg cctttgatta aaacaaacac agcacagata taagcaattg
    36901 tttttataaa aatatttgtt gagatacctt cgccagtatt taagtaattt atgaacattg
    36961 caaacataga taatccaaac ccttgaaatc cgactgtcaa atagcactgt aaaatatctg
    37021 acaaaacttg ttttgatcgt tgtcctgttt ctaagtcagt agcaaatact aaaactccga
    37081 gtacacgttt gaatgctagc tcgagtattg ctgtaattat aatgaaagca ctaaaaacat
    37141 acgctaccgc taaagcaatc aatccaaatg aaattcccca caggttcgct tgatagcgat
    37201 aatatcctga tttgatacca tcaacaaagg ttgacaaaaa attatctgaa aatttagtag
    37261 caacaaattc attatcagaa ttttcaacta attcataacg caggttatca gctgttgagt
    37321 tctctttttc cattttatca attacattat ctgtcaatac ttgcgtaaga tccgttttcc
    37381 aaaaattttc ttttgttaga ttgttccgat cattcgtttt atcgatcatg gaatattgat
    37441 ccgttttatt gatataagct aaatcagtaa ccccttgttc aatcagcgac catgccacac
    37501 cgccatcttg attgttaata ctagttgcgt cattataaag agtctttgca aacattattc
    37561 ctgaaagttt ttctgttgat ccaatcaaag tcggcattaa aagaattaat actatcgaca
    37621 ttacaacatt cattccaaca gattttagat caactgttcc ttttccagtc accattttat
    37681 aaccaataat cactaatgag agtaccatta aaccaataac aactgtattt aaaactgact
    37741 gatagacttt gttcaatcca gcactttcca caaagctaaa caaatctaaa acctcgggaa
    37801 tcatattttg aatgccatcg acaacagcga acattgattt tataacagac caacctatcc
    37861 acataccgaa ctggctgtaa aaatttccgt tatatttttt aagataattc tgataaagtg
    37921 gattagttaa aaactcagtt tgactctcag tatcatcaaa ccagttgaaa atactgcctt
    37981 ctgcaacgtt actcgtaaaa ataatcatag ctatgagaat aagaaaacta atcaacaacc
    38041 aatttatttt tctattatca atcttttttt taattatttt cattgttacc tccctcagcc
    38101 cattttttta ggctctcaga aagcttctga gccatttttt tattaacgat gatgtgagtt
    38161 acgtaatcat cattaacagc tcttaaatct agaacaatag tatttgagca gatactctcg
    38221 attaactcaa gagtatctgc gttatgatca agacagtaaa tcttatctac tagatgattt
    38281 tcaatcaaaa taacccctcc cgtagtcaaa gttctcaatt ttatgaagat atccctctac
    38341 ttcatttaaa tcaattctat tcttattgct gactaacccg ttgtaaaatt ctttttgtag
    38401 attatattta tctgtttctt gaatcttttt atataaatca accagggagt ccctgtcttt
    38461 aaaaacttgc ttgaattgtt cgcttgtata tcggttttca ttaattgcaa caactgcttg
    38521 aatttcaggc catttttctt tcaacttaaa ataacgggga acgctgaaat agttctcaaa
    38581 aaagaagtct cgtgcttcat agtattctct attttgtctt tttatatcct cgacaatttc
    38641 gtatcgtgta gagatcttca aagctgaact ttcgttaatt tctgttcctt ttcgaaagac
    38701 tttcactttt gaagggcgtt caattttata atttatcccc tttttacttg aataactttt
    38761 gatacgacca tcaaattgaa ccatatctcc tttttttaac cacccaaatt ttagaaattg
    38821 tttagttaaa ttcatccaaa tgtggtctgt gaccaactct aagttatccc cttgaacaat
    38881 ttttaaattc gataacataa aagtagcatt ttcatactct tgaccaaact tgtatttatc
    38941 ctttttatat ccgttaaatt caaaggtacc ttgaaatgta tgccgtttct tatctcctaa
    39001 ttttttcaat ttttctctca aaataatcaa ctccatcatt taatatattt ttgtgatggt
    39061 agatactctc gattaacaca agagtatctg cgttgtaatc aagacaataa atttgatata
    39121 ttaaccgttt ttcaatcata ttattaatcc tttctaacct atttttttca gtgtctctag
    39181 catatccagt ctactagctt tttcttgctt agctatgtcc tcccagtggt tcctagctgt
    39241 ggtgttgata aacttcattt catcaatttc ttcaccgaga ttcagttttt catttataga
    39301 attaaaaagt cttgttagca ttttgtttgt tatatcaaaa tagtcttgac ctcgaatttc
    39361 tattttatat tctctttcaa ttgaatcttt catactagca atcaacttaa gatacttttc
    39421 tctttgaact tcagtatatc tatcacctag tctggtaatt atttgaattc ctttctgatt
    39481 tataatattt tcaaaaaagg aattctgatc ttgattaatc tcttctatac tatccttatc
    39541 ttgattagtt tgatcttgac tattctgatc ttgacttaac tgtgtatccg atttgacgtc
    39601 gcatggtata ccagctggat accatttttc catcagatca actcttaatg gttctacttg
    39661 accagactgc aaaatcatat caaattttat tggctttagc tttgagaaaa attctggttt
    39721 taagttcaat aacttgaatc gataaataga aggtttatac ctatcgattc gtatattttg
    39781 attttgtaac cagtggggta gaaacgctaa caaatcttca tttaaaaaaa atacaaaacc
    39841 ttttgtaaaa agtatcttta catcatcatc gggtgttccg agcattttcg tgtatggata
    39901 agcttcgaca attccgtcat catctgcgtt tgtgttcaga tatacgtata ataattttgc
    39961 tgaatctgac atcttcataa aacttgcatt atttaaaaat gatttagcca gcattcgttt
    40021 ttctgccata aaaatcacac ttcttcctat ttgaatgtta aaatgtagtc aaataaagtt
    40081 tagctagaac tttattattg agcgttccta gtggtctgca aactaacggg aacactcttt
    40141 tttattctta ttaaaaccag caatactagt tcaccttctt tcatcctttt acatccaatt
    40201 aaatttgatg ctgtagcatc cattttttta cctcttcttt tgaatatagt tcaattgtgt
    40261 caaccacgat aataggtaat cctaaccttt taaacttcag aaaagttcca tatgatacgt
    40321 ttagaaattt tgccatttct tttcccttaa gaaaaggtcg ttctaatccg ctgtctattc
    40381 ttgcttgatc aatagcttct tttgtcactt caaacacatg tgtcttcaac tgatttgttt
    40441 gatcagtatt caacattaca ctgactccga tttgctccat taaaaattcc cactttcata
    40501 ttttcatcaa taagccaact cgccaagttg tttgttaata atctgatttc aataaccaac
    40561 ctattatttt ttgataaaca tttttcgaca cactttgaac ttcgaagcat tcaatttttt
    40621 taagagtttg ccttgaaatt ccaattaatt ctgctgcttt agttttcgta atcatcaact
    40681 ttcctcgtct ctctcgaatt cttatactaa aatcctcatt aatttgaaac ataaacatcc
    40741 ctccattttt atttttgcat ttatccgttt atccgatgtc ggataaatag attttagtat
    40801 atattatttt gatagtcaat taaaaatata cattttggat aaaattgttc atttttttat
    40861 ccaaatcata tattatagat agtaagaggt gaacttcatt gactcaaaaa aacagaatta
    40921 aagaaactcg cgaagaacag aatttaacac ttaaagaact tagcaatctg tcggatattc
    40981 cgtatcaaac tttgagaaac tatgagattg gtaaaagaaa acccagaaat gatgaagttt
    41041 ggtggaagtt aggtacgatt ttaaacgtcc gtgggcccta cttaaaagga gaagatagtt
    41101 ttaaaacaaa tgatgaattg catatttatt atctaaaaaa aagtcataca aattttgaac
    41161 tgtctaagaa agaagaaatt atagatataa tagataaact aaacgaagac ggtttagatg
    41221 aagccttacg gcagttagca ctattatcaa aaatagatga tttcaagcgg taacttactt
    41281 atcatcatgt agactatcag gtatcataaa ctaattcctc aatcagccaa ctcgccaagt
    41341 tatcagattg gagagattag ttatgtcaat acaaaagtac aaaacaaaaa gcggtacacg
    41401 atatagtgtc cgcttatatg ttcgtaaaga tgaaaatggg aagcaagaat actatgtaaa
    41461 aaaaggcttc aaaactgaaa aagaagccaa gttacacgaa gcaagaaaaa aggtcgagat
    41521 tgaagatatg ggctatcaca gaccttctaa tgacttattt agaacagtct atgaagaatg
    41581 gttgccgtct tataaaaatc gtgtacaaga aacgacttat caacgaacaa aagacctttt
    41641 tcgcttgcat atcctgccaa agttcggaga caaatcgatt tctaagatta ctcctattta
    41701 ctgtcagaat gcaatcaatg aatgggctgt aaaatataca aatatcaagc aacttaaatc
    41761 ctacagctct caaatatttg agtatgcaat cttcgcagaa ttgttacagc gtaaccctat
    41821 gacaaatacc aaactgccaa aacaagaaaa gaaagaatcc gaaaattatt tctcactaga
    41881 agaattaaaa gagtttttgg aaattctcaa taaagaagag tctttaaaac atatcctgat
    41941 ctttcaactt ttaattacta ccggtgttcg caaaggtgaa ttatcagccc tacgctgggc
    42001 agatattaat tttgaagaac agttactaca catcggaaaa agttatgcaa caattcgcac
    42061 tgaagatccg aatgctacta gaaaaacaat caggattcag aagaatacaa aaaatgtctc
    42121 ttccgaacga attttaccga ttgatactca aaccatcgaa atgctgaaac tttggaaaaa
    42181 agagcaagca gaggtacttt tacaattcgg cattaatgca aataccaaaa agcaacttat
    42241 ctttacctat gtaaatgcaa atggcgatgt taaccaacct ttacacgcag attattccaa
    42301 taatattatg agacgtttag agaagaaata taaatttaag cacgttacta ttcatggatt
    42361 gcgacacact cacgccactt tacttttaga aggcggtgcg agcattaaag aagcacaaga
    42421 tcgattgggt cataaaaatg ctgaaactac gctcaatact tattcccatg taactgaaaa
    42481 agcgcaacga aatgcggtag acaagtttat tgcttacact ggattataga caaaaaagtt
    42541 gccgtcatta cctttttcat taccacaacg aaaaaaagca ccttccaact gaatggaaag
    42601 tgcttgaaat cgttggtata acaacgatta acgcttagag aattgtgaag ctttacgagc
    42661 tttcttaaga cctggttttt tacgttcgac catacgtgcg tcacgagtaa gtaagccagc
    42721 acgtttaaga gctaaacgga agtcaggatc aacttctagc aatgcacgag cgataccatg
    42781 acggatagct cctgattgtc cagcgtatcc tccgccgttt acgttaacaa atacgtcata
    42841 tgcgcctttt gtttcagtaa cagcgaaagg ttgattgatt acttcacgca agtcagcatg
    42901 tggaatgtat tcttcaacat cttttttatt tacagtaatt ttgccagttc ctggtactag
    42961 acgtacgcga gcaactgcgt ttttacgacg gcctgtgccg atatattgaa cttgtgccaa
    43021 tgaaattccc tcctattaga ttaagtttgt gatgtctaaa acttctggtt gttgtgctgc
    43081 atgtggatgt tctgctccac cgtatacgtt caattttgta aattgtttgc ggcctaaagt
    43141 gtttttagga agcatacctt ttacagaagt ttcgatcaaa cgacgagaat ttttagcacg
    43201 caattcgcca gcagtgattg atttcaatcc tcctgggtag ttgctgtgac ggtaataaat
    43261 tttgtcagtc gcttttttac ctgttaattt cactttgtct gcattgatga cgatgacgaa
    43321 atcgccagta tccaaatgag gtgtgaaagt tggtttattt ttaccacgta gtacagatgc
    43381 aacaactgtt gaaagacgtc ccaatggaac atcagttgcg tctactacat accatttacg
    43441 ttctacttcg cctggtttgg ccatatatgt tgtacgcacg ttattttcct ccaatttaag
    43501 ttctgatgtt tgacatacac ttcgagtttc cggggctctt tgtggggcaa acaataccat
    43561 ttaacatatt acccgctaat ctagtcaatg tcaacgtttt tctgcttgat tgaaaaattt
    43621 atatgaaact ttacttcttt tctttctttt atataaaagg gtcgtttcct gtcaaaatga
    43681 aaaacaaaaa gaggctgtga caaaagtctt gtcacaaccc cttattttga ataaacggtg
    43741 ttctcctgcc aactcctcgg tcacaagtca caatatccat aaaacataag aagctgtttt
    43801 ttaaaattgt ttcttgtgac tcggagctga acggcaggct tacaacctct tggtaaacgg
    43861 tgttcaatca gctgaccctc ggtattagct caaaaaacgg caaaatatga ggaactattt
    43921 tgacgtttgt ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttttcggtc
    43981 aagttcaaca acagttttta cgcgtcgatc tctggcgctt tgcccaaatg agcttggatc
    44041 atccagatac gtttttctgt ggctgttttg aattcgataa agatatcttg tgttggatcg
    44101 tcgccttctt ctccagaaac ttcgattcct ttttggtaaa gatctgctag ataacgatag
    44161 cctgcaacaa gtgtttccaa acgttctgga atagtacgat cccagcggcc aatttcatca
    44221 gggatttttg tgttatctgc aaattcacgc aatgtagaat aaggtgaacc gtctaatgtg
    44281 atcaagcgtt cggatacttc atctaactga gcgttcaaat catccatgaa ctcatccatc
    44341 attgggtgca atgtaaggaa acctggtcct ctcatgtacc aatgtgtttg gtgaacaaca
    44401 acagacattt ggcttagatc tgcaactaat tgatttaata cttctttggt ttgttggaat
    44461 ttcatctttc ttgcctccta acattttctt acacttaaaa taatagtaga ctttcaatga
    44521 aaagtacaac aaaatcattt acctgagaac gattttcagt tcgctttttt atccgtaaag
    44581 ccaatcattt ttcagaatca gctaattctt ctcgcagttg agcaaattgc tgataagtct
    44641 gtgctaaatg cttttgtgtc gaaacaaata atggatagat tttctgatat tttttatgat
    44701 cagtttcttg tactccaact tgctctttca attctatcaa ttcctgtgct tcactgatac
    44761 tttggatctt tccgatgctt ctccagccta aaatcacagc tcctaatgcg gatgcttctg
    44821 tgacagtagg gaaaacaagc gggtaaccca gtacatcagc catcatctga cgaaaaatcg
    44881 gagattgagc aaacccgcct gtagcacgga tctctgtgag ctgattttcc tggcaaactc
    44941 cttttaaaat ccgataaagg ttgagacaga tcccttctag aatcgccttc atcatttctt
    45001 tttctgtatg ttgccgctgt aaaccgataa aactgccaaa cgcatctgcg tcccaaagcg
    45061 gtgctcgctc accaagtaaa tagggatgaa aaatcagacc attggcaccc gctggcacaa
    45121 aagcgatagc cgaaagcagt gcatcatatg gattttctcc tttttcttta gcagattgaa
    45181 cgacttcctg taaaaatgta tgccctgccc aatcaaagat gccagcacca ttgctagtcg
    45241 ctcctcccac tacccaatgt ttctgatcca gaacataaca aaacgtctcc atttctggat
    45301 ggaactgagg ctgagtagta ataaaacgaa gtgctccgct cgttcctacg gtcaaagcgg
    45361 cgatcgtatc accaaaagca cctaacccta gattagaaag cggcccgtct gcccctccca
    45421 aaacaaatga tatatcattt ggcaaaccta gttctgctgc tgtttttgat ggtagacctg
    45481 ttacttgata ggtggaagga aagacttgcg gcaattgctc tattcgaatg ttcaagtagt
    45541 caagcacttc ttctgcccat tggaattcat ggatatcaaa atatccagtt cctgaagctg
    45601 ttccgtagtc gctgatcagt tcgccaaaca atctataaaa gatatagtct ttgataccga
    45661 caaaataagc agtttttttg aataattcag gttggctgtt ttgcagccac ttgattttgt
    45721 tcaatggtgt cattggatga atcggcgtcc cagtctgccg ataaaattct ttgccaagca
    45781 cggtatattt cagtttttct gcttcgtccg ctgctcggtt atctgcccaa gtgatcattc
    45841 gagataacgg tgttttctct tcatccaaca atatcaggcc atgcatcgca gaggagaagg
    45901 agacaaattg aatgattgtg tctgaaggca actgtttaat tacttctttt ataacggtgc
    45961 agacaccttg aaagatcaat tcctgatctt gttctgccat cccttgtgtt tcttggatca
    46021 aagggtagcg aaaataagcg gatgctgctt cttgggcttc atctgtgaaa gcaactgctt
    46081 tggtttgtgt ggttccgata tctaatccga ttgaaacgtt cattttttca cctcaaattt
    46141 tatgtatgta caaaaattta gtttaagctt gcgtatcttg gttttgaaaa gggggagatg
    46201 gcgtgttact ttattttatc attggttgct gtatcggatc atttttatgt ttaaccgccc
    46261 agcggattcc gttaggtcac tctattattt atcctagatc tcattgtgtc aaatgctgtc
    46321 gttcgctttc ttggtatgaa ttgattccga ttctctcgat catcgtccaa cgatttcgct
    46381 gccgctattg caggtgtcgg ttgcccttct actatttgtt ggcagaagcc ttatgtggtg
    46441 gtctttttgc ctggttcttt actttttctt ccgcaagaaa tttttcgacg ttcatatgga
    46501 tgctttcggc tttgctattt tcgttgatgg atttatttta cttcatggtc cattctcaca
    46561 cgctattctg ttcttgggca attttatgga ttttttggtt gcaggccggc gtcttccaat
    46621 ggcaaagtgt gctgttaacg tttatcgtag gcggtgtgtg ccttcgctat ggtcaatcct
    46681 atctcggagc tggcgatact ctgttgatgc tttcttggag tggtggcttg tctctagaag
    46741 agttgcttca gatcttgttt cttgctagtc tgtttggaat atccgttttt tctgtttact
    46801 ttatctgtca taaaaaaaag ttggaaaagc tgcctttcat tccttttttg agcagtgcgt
    46861 tgctgattgt ccttcatctt aggtattgaa aaaaggttgt gacaaacgac ttgtcacaac
    46921 ctctgatata tagtgttctc ttaccaaatc cttgtgactt ggagctaggc gacaggttca
    46981 caacctctcc actaaatggt gttcaatcag ctgaccctca gtattagctc aaaatgctgg
    47041 ttttacaacc tctgatatac ggtgttccat aagtagcttt ttcggcttct tatttcttga
    47101 cgccccaatg tcgacgaagg aaacctgcac gtccagaacc ttctcgataa agattgtaat
    47161 ggagcttgtt tttcttgtaa taatcctgat ggtaatcttc tgcaggataa aattcgcttc
    47221 ttggttcgat ttttgtcacg attggcttat cgaatcgccc gctgtcttgc aatgcttgtt
    47281 ttgaacgctc tgcaatattt cgttcttctt catcattata gtagatcact ggacgataag
    47341 aatcaccgcg atcagcgaac tgtcctaatg cgtcagtcgg atcggtttgc tgccaataga
    47401 tttccaccaa ctgatcataa gaaataactt ctggatcata ttcgatctct actgcttctg
    47461 tatgccctgt tgtgcctgtt gttacttgtt cataagttgg atttggtaca tgcccgccag
    47521 tataaccgga tgtcacagaa atgatccctg gctgctcttc aaatggtttg accatacacc
    47581 aaaagcatcc gcctgcgaaa actgcttttt ttgtcatata aaatccccct tttttctcat
    47641 cataccttga tttccaaaag gaggataacg ttttgcttgt gacagaaaaa acggaaacta
    47701 ttatatacgt gatacggctt ctgataaatg ccaaaacgaa cgtacttgat caaaaacggt
    47761 taaatcagga atcacatatt cagcagaagg aagatttatg ttttcaccta ttcccaatac
    47821 atgcatgtta ccagccaaag ctgcttgaca accagcttct gaatcttcaa tgaccaagca
    47881 tgcatttggc ggtacattca attgctgtgc tcctttgaga aaaacttctg gatcaggttt
    47941 tgcttttgat acttgcgtgc cgtcaataag gacatcaaaa taacttgtca aattcgtttt
    48001 ttctaaaatg aggcgtgcat ttttgcttgc tgatcccaat ccgatcttga tgtttgtttt
    48061 tttcaagtac tcaagaacag ctattgcacc aggcaaaacg gatgtttcat ccattttttg
    48121 aatcgcttga agatatagat tgtttttttg ctcagcaaag gctgatttct ctttttctga
    48181 gaatttctgt tccatttttc caaatgacag caatcgctct agtgactcgg ttctggatat
    48241 tcctttcagt tgctcgtttt ctttctcagt gaatggaatg gacagctggt tagctaaaac
    48301 cagccacgct tcgtaatgat aacgagctgt gtctacaaga acgccatcta aatcgaatag
    48361 tgctgctttg attttcatcg attacctcct tgaaaatgaa cgacttgaag taaagatgcg
    48421 atgtttttag ctgtgcgatg aagattatca gtggcttgct gtaaagcttc ttgtaaaggc
    48481 acagctgcag gaaggatcgg aaaaacggcc gaaatgccaa catctgctgc tttttcgctt
    48541 cctttaccaa cacttccgca aatagctatc acaggaacgc cctctggtac tcttctagca
    48601 atcccaactg gcgcttttcc ttttagactt tgtccatcta gacgtccttc gcctacgatt
    48661 acgaggtctg cttgctgtac ccgtttatcg aactccagta aatccaatac gtagtcgatg
    48721 ccagagacta ttttccctga agcaaatgct aacagtcctg cacccattcc accaccagca
    48781 ctactgcccg atgcctcgat tacttgaggg gcaaatctca tataaaaatc atgcatggct
    48841 tggtcagcca ctgctaattc attttctttc aagccttttt gtggtccgaa aacaaaagaa
    48901 gcgccttctt ttccgcataa aagattagta acatcagtaa tgacagtgat tttggcttta
    48961 atcagctcaa taggcacgtt cgttttatca actgtagcaa ttttacctag attttctccc
    49021 agtgcttcta ctttttgatt atcttgatcg taaaaagcat aacctagacc ttctgccatg
    49081 ccgatgccgc catcgttggt actacttccg ccaacgccga tgatgatgtg tcgaacacct
    49141 tgttgcaaca attgtcgtat cagttctcct actcctcgcg tggataacct aagtggctgt
    49201 tgttggttta gtgggacatc tttcaatccg acgatttctg ccatttcaaa aatcgcagtt
    49261 tgaccgtctg aagcgtactg gatttctttg tttttgccaa atgcattagt aacgactgct
    49321 gtttgccgct tcaaccttaa actgtctgct aatgatgaaa ccgttccttc tcctccatcg
    49381 cctataggta gcagatcata ttcagcctga acaaaaactt cttgaaaacc tgattgaatg
    49441 gcttgtgctg cctctaaggc tgtcagactt tctttgaaag aatctggcgc aatcagaata
    49501 cgcattattt tcccctccgt tccaagatca gttctttttc cagctggtat tggtctccat
    49561 tgacaaaaat aggtaatgtt tctttcgtct ctttttttat tactatttgt ttttttgtca
    49621 aaacaaatag caacctgtga tttttccaaa taaaaggaaa agaaattttt tcccatgctg
    49681 aaggaagtct tggagaaata gaaagagttc cattcgttac tgtaatacct gaaaaaccaa
    49741 atataactgc tagccatagt gctcctaatg aagcagcatg aattccgtca tctgatgaat
    49801 gcggatctgg tcctaaatca atcaggcacg cttcttggaa taaatgatac gcccattcca
    49861 tttcttggat acggcaagcc tctatggcgt gaatcgcttt actcaacgat gagtcgtgga
    49921 ttgttttgtt ttcatagtaa tgcaaattct tagaaacgat tggttgagaa aaatactcag
    49981 gtaataagta taacagcatg acaagatctg cttgcttgct gacttggagt tcatttactt
    50041 cgctacgggc ataatcaagt aaaatagact ggctgccagg acgttctttg taagtggtca
    50101 aatcaataac tggcttactg agatacgtgt catcttgcgg aatcagctgt tctttgttag
    50161 gcactggcaa atataactta tctaaaaaat tttgacattc tttcaaaaaa agcggatcgc
    50221 cagcttgata tttaacagct aaggccacat tataatgcgc cagatagttc gtatatgcat
    50281 tattgtcgat atattctgtg tattcatctg gaccaatgac tctgtgtatc tctaaatgat
    50341 catcgacttt tacagctctg ctcagccaaa aagctgctgt ttcatgaatg agcgtttttc
    50401 cctttgtttc taaaaacgat tgatcctctg ttgcttggac atactcttga acggcataag
    50461 caaggtctgc actgatatga tgttctgcgg cagctgaagc aacttcttgt cttgttccgg
    50521 ttttgatatt caatgcagca aatttgggtg tctcttcctg accagtgtgt gcgctttccc
    50581 atgggaaaag tgcaccttga tagtgataat ctcttgcttt ttgccgtgcg ccttctaatc
    50641 gatcataacg gtacagcagc aaattctttg ctacttcagg aaactgatat aaaaagaaag
    50701 gcaggataaa aatttccgta tcccagaaaa catgcccttt ataaccttcg ccagttagtc
    50761 ccttcgcccc tacactaaca cttggatcat tgcggggagt cataatctgt aaatggtaag
    50821 cagcgaagtc catcgctaac tgatcgaaag aagaatcgcc ttggatcgtt atccgatgct
    50881 gatgccaaaa atctgtccaa taagacatcg actgctctaa aatttctgta taactaacgc
    50941 ttttctgggc ttgggcaata cttttcttaa acgggtctgt ttgctgaaga gaggtagaga
    51001 gcacgatgat cttctccagc gtaaaggacg tattttttct gatcttttct gaaaaggaag
    51061 cggtgatccg gcgatttttt gcttggaata cacctgcttt attgaattta gctgcaatcc
    51121 caatatcaat tttactttct gttgtctggt aggatgcact gatcaaatcg tcaccaaata
    51181 ctcgcagttc tttttcaacc aactgctgtg taccaaaatt ggtttgctgt ccatcgatac
    51241 ccgttttcac atctacttgg cagtcttcgg tcaacggctt gatgaccact ttcagggctg
    51301 cctgatggag attattttga tcagcaacac gacaagtaat gacttccact ttttttcctt
    51361 gagcagtttc aatgagcgca tagcgtttaa gctctcccat ttctaaatct agtgcccgct
    51421 cgtatgcaag aactttcatc gtctcaagag aaaaatgttc accgtcgatt tttatttccc
    51481 atctgatgac atctgggaga ttcactaact cggctgattc tgctcctaaa ggtcggttat
    51541 atacaccagc tgcaaacatt ccccttactt gattccgata gtcttcctcc tggcttcctc
    51601 tgataccaaa aaatccattt ccaatggtca tctgactcgc atacttattg atatactcta
    51661 aatcaaactg tttttcttct actttcataa ggtaataact tctcctgttt ctgccgaacg
    51721 atataaattt tccaccagat tctggatgac atatccttgc cagccatctg caatcatctg
    51781 agtctggtca ccgagcgccc gattcacaaa atgagccata cttagttcat gtgggtcatt
    51841 aactggcgtg gtcttttgta aggaaaccag ctttccatct acatcttcga atagttcgcc
    51901 tggatacaga ttagcacctg cctgatcgcc acaaaaagcc acattcagtt tgtcttctct
    51961 gatattcaaa gcaaacgaag tattcagttg gatgatcttg ccgttttcta attccagtgt
    52021 gccaaaaatt gcatcttcta ctgtgaattt gcttggatcc catttcccga atttccctga
    52081 attttttttc gtaccaattt tttggaagct gtacgcccga acgcttttta ctttaggaaa
    52141 tccagtaata tacatcgctg tatcaagcat gtgaatgcca taatcgatca aaggcccgcc
    52201 tccttgaagt tctttgtcga taaacgttcc ccagcctgga acaccagacc gacgaagcgc
    52261 attcgcttct acgtaataaa tatccccgag aacatcaaga tgattcttga tcattgttgc
    52321 ttcgtcagaa aaacgatgct ggaatccata agccaaaatc tgcccgtttt tatcggctgt
    52381 ctctgccatc tttcttgctt gatcagctgt catagctggt ggtttctcgc acatcactga
    52441 agcattagct tcgagggcag ccaatacatg ttcgaagtga aagcgattgg gtgtacagac
    52501 actcacgata tcgggagaaa tctcattcag catttgtgta actgatgtat acgcatgaga
    52561 aaatcctgta cgtcggcaaa agtcttctgc tcgctggctg actggatcaa ccacagcggc
    52621 caattctaag acatctgatc ttttttgata ataagcagca tgtacttttt ctgctacttg
    52681 tccagcgcct atgattgcta ctttcttcat ttatttctcc ctcctttgct tatttactta
    52741 ttgttattct ttctctattc tttctctaaa tcatttaaat gacgcgctgt ttccagacag
    52801 tttttcaagt attgcaatga ttcctgataa attttcactt cattttctcc tcgcaaacga
    52861 cattcatata ccatataacc ttcatactca ttttgaagta gcgtttgaaa atggcgagta
    52921 aaatcaattg cgccagatcc tggttggtag cgatgattat ctgctaaatg gatatgaccc
    52981 acatactctt tttgcgtagt caatgctttt gaaatatcat cttcttcaat attcatatga
    53041 taaaaatcag cgatgatctg cacatgtttc aattgattag agtcaatgta atgacgcgca
    53101 tccgctaaca aattgatcat atggtcttgg tatcggttca aaggctccaa ataaataacc
    53161 gtacctgttt cttcggctac tttatctaaa taacgaagtg attcgctgac tgctttatag
    53221 tctccttctt tgcttcgggg tgaaaccatc ggcggtaatc gataagtgaa cattccccaa
    53281 gctgctggga taacgattcc tttgcctcca acctcgctta gtgcacgcaa aatctcagca
    53341 atttgacgta caccattaag acgccgttct tcgataaagt caccgatcca cccatcgtag
    53401 ccgttacaag ctgtcactac tgggatccct gtttctttga ttgcctgttt gactgtgtcg
    53461 atattttcta ttaacaactt accgtcgatt tcgtattctt caaatccaca gtctttgata
    53521 aatctaaatt tttctaaaat gtctcttggg aaaaatgctt gatcttgcgt accgaatttc
    53581 attgttctcc tcctcggact tgaacgccca ttttgatact ttcttctggg tgctggtcta
    53641 cataacgcat gtaagcttct gcgctttctg caaatggcac aactggatca atgatttctt
    53701 cacaatccaa gtaaccgttc atcaataatt cccaacatgt gtcctcgatt cgtttacggt
    53761 tccatcttgg gtaatctggg tttggttcac tagatgctcg agcaaagacg atttttgcat
    53821 tattgaaatg tgcttcgcga ccaagattaa acccagctgg aaaaggttta gcaaaggcaa
    53881 cataagaaat gatcccgcca tagccgatcc ctcttaaaga agcttgtaat gcggcagcac
    53941 tgccactcgt ttcaataact gaatctactc cacgtttatc tgtcaattcc tttagacgaa
    54001 aaccgacatc tgctttcata ggatctagcg tgtaatcggc accgtatttt tctgctaatt
    54061 ctctacgctg cgctatggga tcgatcccaa cgatggtagt agcacctgct tttttagcta
    54121 attgaatcgc aatttgcccg atagcgccta aaccgaagat tgctacagca tcacctgctc
    54181 gaacatgtgc ttcccggata ccacctaaag cgaattgagc aggatcgtaa catactgcat
    54241 ttttccattg atccaaccga tcaagtttac gtagtttata attatcaaca ccgtttgtaa
    54301 tcagcgtttc acgaatgggt ccataagtgc agactaactc tcctttttga tactctgtca
    54361 ccaaactgcc cgtttcttcg atcgtaccga caatcatatt tcctaattga aattcgccaa
    54421 ataccacacc gcgttggctt ccttcttctc ttggcaagaa taggcgccat tcttctgaaa
    54481 attcttcatc gataaatgga cttaatcctc taaagtcgac aatttctgtt cctggttttg
    54541 gagtagcgaa aattactcgg atacgtactt cgttcttttc gatctcacgg tcttcgtaat
    54601 ctttgaatcc ggctattctt ggttctaatg caactaattt tttcatcttt tctttcctct
    54661 ttcttttctt tttatccttt tacgccgcct tcgactaaat cacctttaat aaatcgttca
    54721 gataacgcat acataatgat gactggtaaa gcggtcacca atgaagcggc catcattcgt
    54781 ccccaaatgt agtctggtgt actgaataat gtgttcaaac cgattggtaa agtaaatttt
    54841 tcggaggtcg acaggaaaat cgaagcaaat aaataatcat tccacgaaac cataaagcaa
    54901 taaacgaaga cagaaatgat tccagaaata gccaatggta taatgatccg aataatgatc
    54961 tggatccggc taagaccatc gatcattgct gcttcttcaa tatcagtcgg aatcgtgtca
    55021 aaataacttt ttagcatgaa tatcgcagta ggaagtgttt gaacgaccat cgtgataatc
    55081 agtgctgtat tggtatcata caaacctaga ccggaaatga ttttaaataa tggaacaacg
    55141 atcaaaatac cggaaaacat ataaacggtg taaaagctag cattgatttt cgagcgagct
    55201 ttgaagcgta gttttgacaa agcgtatgcc ccgctgatcc caatcactac tgcagttacg
    55261 gaggctatca aggagatcac taaactattt ttgaaataca tgatgaatgg aaaaatctca
    55321 gcattgaaaa tatcctgata atgttcaaaa gtccattctt tcggaaaaat agtttgtgtc
    55381 gttgcaattg cttcttgtga atccttgaat gatgtcatca gcatgatcaa aaatggaaac
    55441 aaattgacag ctaatagcaa caaaatcgtc gcgtaaaata agattttcct gctcttttta
    55501 tttttcattt caagtccacc ttctttcgtg agagcaagac gaccgctgca ataatgatga
    55561 acaatagaat cgatatagct gctgcttttc caagatcatt gaacgcaaag gctgtctgat
    55621 acaaataaac gcctaagata ttgactttat tcgtcagtag atagacatct gtaaacatat
    55681 agaacatcca gatagatcgt aaaacaatca cagttgctag tactggtttg attgccggca
    55741 gtgtcacgat cttgaacttc tgccaagcat ttgcaccgtc catttcagct gcttcataaa
    55801 gcgttttgtc gactgtttgc aaaatagcca aaaatgaaat aaacgcatac ggatagtatc
    55861 tccagatagc aaacaaaacg accataaaga agctagcaac tggctggtcg aaccacagcg
    55921 gtgcttcgtt gaaaagctgc aacctatcta ctaacagatc attgacgatt ccataactat
    55981 tattgaacat atatttccaa gcaaaaatca aagaaataga tggcgtaaca taacttaata
    56041 aaatcagtga acgcaccgtt ttcctaaatc tgaacttgcg gttaagcaaa atagctacgg
    56101 ctaatcctaa agctgtactg cctgctacaa ctaagaatgt gtaagcaact gttaaaccta
    56161 aagaacgata aaattcacta tcacttaaaa tttcaagata attgcttaat ccgataaaaa
    56221 cggcgtctga gttaggattc agcggcatat cgaaaaaact gatctgaata ttggaaagca
    56281 ttggaatcag cactaaaaca gctaataaaa gcatgcttgg tgctaaaagt cccatggcta
    56341 attttaagtc agaatgtttc cttggacgat tcattgaaac ctccccctga taatctgcca
    56401 atagctatct acttttttcg aacaccattg gcagaacttc ttgttatttc gtattttttt
    56461 gtgcgtcagc taaagcttga tcgacatctt cgtttccgac agttacttgg ttcactgctt
    56521 ttccgatcac acctgagctt gtgatatctc ccattttcgt gaaattcttt tccccgacta
    56581 gtccaaagac ttgtacttca tcaaaagcac tagcaatctc agatggcagc tcgccaaaag
    56641 acttgatgac ttcattttct ttgtaaccat ccagttcgac tacttgttta ttcactggtt
    56701 gagcaccacc aggagacatc aagacccact tttccatgtt tttcggttga gataagaaag
    56761 ctgtgaatgc ttcagcagcc tctttttgtt tctcgtctag accagaagaa atcgtcaatc
    56821 cagatactgt gccatagaca gcttgatctt tttgtgttgg gatagcaaaa ccgatatttt
    56881 ctgagttccc cgcttcataa acagaaggca aaatgtaagt tgaatagatt gccattggtg
    56941 ctgttccatt catgaaagca tctttgattt ctgtcacatc attagagcct ggcatcgtgt
    57001 attgggataa gttttgataa aacgacaatg cttctctcat cttttccgta tcgatcgtta
    57061 cctcgccttc atcatccaaa acatttgctc catttgacaa agcaaattga gagaacgctt
    57121 gctcactcat tgttccttca gcagtaggca tagcaattcc atattgttta ttctctttat
    57181 ctgtgaaatg ttgagcaatt tttaaaatat catcccaatt ttctggttct gaaaaaccag
    57241 cttctgataa tttttctttg tcataccaaa taccttgaac ccagccgcta attggtgcag
    57301 caatatagct ttttccatct tctgaacgaa caaggttttt ggctccgtca taataattat
    57361 cttctccagc ttcctcgata acgttttgga ctgccgtctg atcaatcagt tcatctttat
    57421 ccatcacttt agcaaaatcc tgactgactt ccattacttc tggtaattta ccggaacgag
    57481 ctaacgtaac gatttttgta ttgaacgctg attcttctac cggcacttgc ttgattttga
    57541 tgtctggatt ttctttttca aaatcagcaa ccagttcatt gatcacactt aatcgttcct
    57601 gttcgacaga agagtgcatg aattgaatcg ttgtctgttg tgattcgtta gagctttgac
    57661 tttcaccaca agcagtaaga agaaatccag tagctagcag acaggtagta acaataattt
    57721 ttttcatttt tttccacctc ttattttatt attttcagcc acatatattc atacggctgg
    57781 aatatcaact ttcgttcttg actgcaatgg ataatttgtc cagaaaacag gtctaggtaa
    57841 tctccttttg gtaaaagata acctgctgat tgattggaaa aattatggat aactaagact
    57901 ttctcttcct tcgcttcgcg aataaaactg ataaaagaat ctgctgagtc cagtaagtaa
    57961 atcaaactat tcggatggaa ggctttttct ttttttcgaa tagatagcat ctgggtcaat
    58021 tcaccatata ctgctgttct taatggatct gtctgcaact ctttctcaat atctgctaac
    58081 aaaaattttt gccgattgat ttttcgattc tctcctgttt tttctacgcc tttgtaatca
    58141 tttcgacttc ccagcacact ttgaatataa attgccggca cgcctggtaa cgttaccaaa
    58201 aatgaatgag cagctaaaaa gcgtttgctt ctccattccg tcgtatctgt tggagaactt
    58261 aacgcatcta gatacgtagc gtttatctca tatggactgg tcgttccatc tgggtttttc
    58321 ttgtagttta ctcgggcacc ctctttcttc agctgttcca ctaattcaag gatcgttttt
    58381 tccggcagaa tacctcgtac cggattcaat ccgataccgt catgggaggc taaaaaatta
    58441 aaaaaagttg tttttttcga tgcgaaatcg atggttttta accattcttt caacttactt
    58501 gtattacccg aacgaatcgc ttgaagggtc aaaggtggta gcgaaaactg atagaccatc
    58561 tgtgcttcat tctcgccatt cccaaaataa ctgatattat ctttgtgtgg cacatttgtc
    58621 tcagtgatca ataccgttcc tggagctgct tcatcagcga ttgcacggaa taattggatg
    58681 attttatgcg tttctggcag gtgtatacaa gaagttccta gttctttcca taaaaatccc
    58741 acagcgtcca agcgaataaa tgaagcgcct ttttctaagt aaaacaaaag aatatcgatc
    58801 attttcaata aaacttctgg atttttaaaa ttcaagtcta cttgatcttc gctaaaagtc
    58861 gtccatacgt gtttttcttt cccgtttttg tcaatgaacg ttgtaagtaa cgggctggtc
    58921 cttggtctag tcacgctgct tgtatctgta tccagtggca aatcaataaa aaaatctttg
    58981 tacgtatcat tcaagtttaa atattcctga aaccaagtac tttcggcaga catatgattg
    59041 cagacaaagt cgaacattaa ccgtgtttcg cttctcattt cttctatatc ttcccatgtg
    59101 cccaaacggt cgttgattgc ctgataattt acaacggaga aaccatcatc agatgtatat
    59161 gggaaaaatg gcaagaaatg tacaactcta aatgtatctg ccaaatactt ttgataaaat
    59221 ttcttaaatg tacgcaaagt tggttgctgc tcttcaaaaa attgatcccc ataagtaatc
    59281 aagaaaatat cttcttcgtc ccaatgcagt ttgcctgcct ggcctttctt ctgctgataa
    59341 acactgactt tttgttcaat catagaggcg gttttctcag acaaatctga gtcgcgataa
    59401 atcgcttgta aaagttttgt atacatcgga ttcccctttc ttttttggga gcgttcccaa
    59461 cgatttgatc atattatgga aaacgcttac tgtcaatagc atttttttaa ataattttga
    59521 tatacacaaa aatacaaata agaaagctta tgtatcaata attaatagct tcttaaaaaa
    59581 atatggtctc tcatgatcat gcaagctatt cctaaatttt caaaatcata gacaaaaaag
    59641 aatgtctatt gtactatgga attattctaa aacgctccca aaaaggaggt gcatataaaa
    59701 ttgaaaccta ctatttatga cattgcgaaa aaagctaatg tctcaaaatc aactgtctcc
    59761 agagtattaa ataaccagcc aaatatctct gataaagcaa aagcaagtgt acttcaagca
    59821 atcaaagaat tgaattatga accgagcaaa attgcaagag gactgtcagg aaatggtttt
    59881 gacgcgattc tagcattatc tcatcgtact tctcatacga cctatggcaa tccttttttt
    59941 tcagatgtta ttcaatccat ttctgccgtt tctgaacaaa ataacttcga cttgattcta
    60001 caaacggcaa aaacaccaga agaagagcta gaaaaatgcg cgaaaaagat ccaagaaaaa
    60061 atgatccgag gaattattat tttaagctct acgatggatg aaacacttct ttttgaattg
    60121 gatcaataca atattcctat tgtggtaatc ggaaaagtcg gaaacgacta cacgaacatc
    60181 tactcagtgg acacggataa tttccaggat agttacgatt tggtggaaac actgatcaag
    60241 aatggacacc gtcatatcgg ctgtctccat gctccgacag aagtttatgt atccaatgat
    60301 cgtctcaatg gttaccgtca atgcttattt gatcaccacc tagatatccg taatgaatgg
    60361 attatagacg gcggctttcg cttagaagat agcatggcag caatgaatga tttaatgaag
    60421 ctacgagaaa gaccaactgc gattttttct accgatgcat taaaatcatt gagtatttac
    60481 aaagtggcag aacaatctgg aaagcagata cctgatgatc tttcgatcgc aggattcagt
    60541 gatcccttat tgtcctccct attttcgcca cagttgactc ggatagacat tccgacaaat
    60601 cagttaggaa tcaaagccac agaactttta ttccaactaa tccaccacca ataccctgaa
    60661 gaaaaaagaa tcattctttc aaccgagatt actctcacag attcgatcca acaacaagaa
    60721 atgtagaaca gaattataaa agaacagaaa cactgaggat aagtcagtta ctctgttctt
    60781 ttttcaatca ctcatccctc gttaccccct cccggtattt tagcgaattt ttcttatttt
    60841 ccatctgttt tagatagctg tggataacta taatgtttgt gttaaactat tttttccaca
    60901 gggaagaaaa aactattttt aaccacgttg tgtataagtt tttatagttc gtttttttaa
    60961 acacatttac ccttatttca atccatgtta tttggggata cttatctcta aaacataaat
    61021 agaataacag acatgtctac tggttttgtt ttattcgagg aattattcaa taatagctag
    61081 caaaatatta aaaataaccg ctctatcttc ccatcaattt attttgcatt caaaaaatga
    61141 tctatcttta cttttgttga ttgacttctc ttggaagatg atcgttccga taccttaatt
    61201 ggatacgaac cgatgttgtt aagatccttt cccacttttc ttctagttag acaaattatt
    61261 ttagacaaac caaaaaagag gttgtgacaa taatttgtca caacctcttt tttaaaatat
    61321 ctattttgtt tgattgttca ttgcgtcttc tgcagccatt tgcgcttcaa tatctgaaat
    61381 actgtagaca ttttcgcttg ctacaccgac ttcttttggt tccatgtcac gataacgttg
    61441 cataccagta ccagctggga tgatcttacc tataataaca ttttctttca aaccaagaag
    61501 aggatctttc ttaccgcgga tcgcagcatc cgtcaagaca cgagttgttt cttggaatga
    61561 tgcagcagat aagaaactat ttgtttctaa tgatgctttt gtgataccta gtaagacagg
    61621 tcgagaagtt gcaggaacgc ctcctgagac tagcgtattg tagttttgat ctttaaagtc
    61681 tgcgatgtct aataatgtac ctggtaagat atctgtatca cctggatcca ttacacgaac
    61741 tttacgcagc atttgacgaa ccattacttc gatatgcttg tcgccgattt ctaccccttg
    61801 catacggtaa acacgttgta cttcacgaag caagtagttt tcaacagata atacatcgcg
    61861 aacttgcaac aattgttttg gatcgattga tccttctgtc aatggtgcac cacggtggat
    61921 catatcgcct tctgctactt tcatacgtgc tgtataagga acagtatacg tacgtgtatc
    61981 tgtttttcct ttgattgtta cttctttggt acgtgttgca ggatcttctg agatatcgat
    62041 gacatcccct gttacttctg tgatcactgc ttgccctttc ggattacgtg cttcaaagat
    62101 ttcttggaca cgaggaagac cttgagtgat atcgtctccg gcaaccccac ctgtatggaa
    62161 tgtacgcatc gtcaactgag taccaggttc accgattgat tgagcggcga tcgtaccaac
    62221 tgcttctccg acttcaacgt cagagccagt tgcaaggttg cgtccgtaac aatgtttgca
    62281 gacaccatgt tttgtattac atgtgaagac agaacggatt gtcactgttt cgacacctgc
    62341 atcaacgatt tgttttgcga tgtcttcgga aatcaattgg tttcctgcaa tgatcaattc
    62401 atttgtttca ggatgacgta cttctttacg ggtgtaacgt cccactaaac gatcttctaa
    62461 tgattcgatg atttcatttc cctcgcggat ggcttggatt tcaagacctc ggtcagtacc
    62521 gcaatcttct tcacggatga ttacatcttg ggccacgtca accagacgac gagtcaagta
    62581 acctgaatcg gcagtcttca aggctgtatc ggtcatccct ttacgagccc cgtgagttga
    62641 gataaacatt tccaagacgg atagtccttc acggaagttc gaaatgattg gcaattccat
    62701 gattcgacca ttaggagcgg ccatcaaacc acgcattccg gcaagctgtg taaagttgga
    62761 aatgttacca cgagctccag aatcagacat catgaagatt ggatttttcg cttccaaacc
    62821 ttccatcagt ttttgttgga tgctgtcttt tgcagcattc caaacagcaa tgacacgttc
    62881 ataacgttcg tcatctgtga tcagaccacg acggaattgt tttgtaatag tttcaacttg
    62941 tttatgggca ttttcaatga tttcttgttt ttcattcagt acactgatgt cagcgatccc
    63001 tactgtgata ccggcatgtg tcgaatgttt gtaccctaag tctttcatac ggtcaagcat
    63061 cttagaagtt tcttttactt tgaatcgttt gaagacttct gcgatgatgt ttcctaagtt
    63121 tttcttcttg aacggtaata ctaattcttg ctctttgata tgtgcaggaa tatcagtacc
    63181 agcttcaaca aagtatttgt ccggtgtttg gacggtcaag ttgaagtctg ttggttcatt
    63241 cagataaggg aattcaggag gcatgatctc gttgaagatg atcttaccaa ctgttgtgat
    63301 catcgtacgt tctttttgcc attcagtaaa tggtttttca cctaatgagt tagggttcac
    63361 accgatacgt gaatgtaaat gaacatatcc gttgcgccat gcgataacgg cttcgttttg
    63421 atctctgaag accattcctt cgccttcgcg tccttcttct tccattgtca agtagtagtt
    63481 acctagaacc atatcttgag aaggagtaac aactggttta ccatctttag ggttcaagat
    63541 gttttgagca gctaacatca acatacgtgc ttctgcttgt gcttcttcat tcaatggaac
    63601 gtggacagcc atttggtctc catcgaaatc ggcattataa gcttcacata caagtggatg
    63661 caaacggatt gcgcgtcctt gtactaaaac tggttcgaat gcttggatac caagtcggtg
    63721 aagcgtaggt gcccggttca gcaatactgg gtgttccttg attacgtctt ctaaaacatc
    63781 ccatacttcg tcttcttgac gttcgatttt acgtttcgca tttttgatgt ttgaagctag
    63841 ttcgcgttga acaagctcac gcatcacgaa tggtttgaat aattcaatgg ccatttcttt
    63901 tggaagtcca cattggtaca tcttcaagaa aggtccaaca acgataacgg aacgacctga
    63961 gtagtcgaca cgtttaccta gcaagttttg acggaaacga ccttgtttcc ctttcaacat
    64021 atgagaaaga gatttcaatg ggcggttacc tggtccagta actggacgtc cgcgacgacc
    64081 gttatcgatc aatgcatcta ctgcttcttg cagcatacgt ttttcatttt gaacgatgat
    64141 tccaggtgca ttcaagtcta acaaacgttt caaacggtta ttacggttga ttacacgacg
    64201 gtaaagatca ttcaagtcac ttgttgcaaa acgtccacct tctaattgaa ccattgggcg
    64261 taaatctggt ggaataacag ggataacgtc cataaccatc cagcttggtt gatttcctga
    64321 agcgcggaat gcttctaaaa tatccaaacg gcggattgca cgtgtacgtt tttgtccttg
    64381 tgcagatttc aattcttctt tcaattcggc tgcttctgca tctagatcaa cattatcaag
    64441 taattgttta atcgcttctg cacccatagc agcttggaat tcttgtccat attgttcacg
    64501 tttttcgcga tattcgcgtt ctgtcaacaa ttgttttttc tctaaattcg tatttcctgg
    64561 ttcgatgact acatatgaag caaaataaat gatttcttcc aaagcgcgtg ggctcatgtc
    64621 taatacaaga cccatacgtg aaggaatccc tttaaagtac cagatatgtg aaacaggagc
    64681 tgctaattca atatgtccca tgcgttcacg gcgaactttc gaacgagtaa cttccactcc
    64741 gcatcgatca caaacgattc ctttataacg gatacgtttg tattttccgc aggcacattc
    64801 ccagtctttt gtaggaccaa aaatccgctc acagaacaac ccttcgcgtt caggttttaa
    64861 ggtacgatag ttaatcgtct caggtttttt tacttcaccg taagaccagc ttctgatttt
    64921 ttcgggagaa gccaaaccta tttgcatact ttcgaattta tttacatcga tcaaaagggg
    64981 ttccctccat ttcatttaat ggcaaaccgc aagacggctg atcttcgacc gccttgcagc
    65041 tcatagaccg gattagtcta aattatcttc tgcggtttca aagttttgga tgacatcgtc
    65101 tttttcatct tccacttgtt cagcagcttt cttttctaat tctttggcag tttgctgttc
    65161 ggcaaatttt gtcaaagcat caacagtgat caaatcgtcg tcttcatcgt ccatgtcgcg
    65221 aagttcgatc tctgtttctt cgatatccaa gacacgcatg tccagaccta gtgattgcaa
    65281 ttctttcacc aatacgcgga atgattccgg tacacctggt tttggaattg gttcaccctt
    65341 gacgattgct tcgtatgttt tcacacgtcc gactacgtca tctgatttgt atgtcaagat
    65401 ttcttgtaaa gtataagccg caccgtaagc ttccagtgcc catacttcca tttcaccaaa
    65461 acgttgtcca ccaaattgag ctttacctcc caatggttgt tgtgtaacca atgagtaagg
    65521 tccgattgaa cgtgcatgca atttgtcatc gaccatgtga gcaagtttga tcatgtacat
    65581 cacaccgaca gacacacgtc catcaaatgg ttcacctgta cgtccgtcgt acagaacagt
    65641 tttcgcatcg ctggccatac cggcttcacg aactgtttcc catacgtctt catcacttgc
    65701 accatcaaat actggcgttg ctacgtggat acctaactga cgtgcagcca tacccaagtg
    65761 taattccaat acttgcccga tgttcatacg tgaaggcacc cctaaaggat tcagcatgat
    65821 atcgattggt gttccatcag gtaggaatgg catatcttct tccggcataa tacgggatac
    65881 aaccccttta tttccgtgac gaccggccat tttatcccct tcatggattt tacgtttttg
    65941 aacgatataa acacgaacta acatgtttac gcctggtgac aattcatctc cagcttcacg
    66001 agtaaagatt ttcacatcgt gaacgatacc gccgccgcca tgtggtacac gtaatgatgt
    66061 atcgcggact tcacgagctt tttcgccaaa gatcgcatgc aatagacgtt cttctgcaga
    66121 taattctgtt accccttttg gcgtgacttt ccctacaagc aaatcgccat cttggacttc
    66181 tgcaccaata cggatgatac ccatttcgtc taaatctttt aatgcgtctt ccccgacatt
    66241 agggatttcg cgtgtgattt cttcaggtcc taattttgta tcgcgggctt ctgattcata
    66301 ttcttcaata tggatagaag tgtatacgtc atcttttacc aaacgacggc tcatgatgat
    66361 cgcatcttca tagttgtacc cttcccaagt catgaaacca actaaaacgt tttggcctag
    66421 agccatttcg ccttgttcca tagatggtcc gtctgccaga gtatcccctt tttcgacttt
    66481 ctcacccaaa tgaacgattg gacgttggtt gtagcttgtt ccggagtttg aacgacggaa
    66541 ttttgttaca tcgtatttat ctaatgcacc gttgtcgcgg cgtacgcgga tttcagaagc
    66601 atcaacgtat tcaacgacac catcatgttt acataacaaa gcagctcctg agtcatgcgc
    66661 tgatttgtat tccataccag taccaaccca tggtgcttga ggattgatca acggcactgc
    66721 ttgacgctgc atgttggcac ccatcaaggc acggttggag tcatcgtttt ccaagaaagg
    66781 aatacatgct gtcgcaacgg caactacttg tttaggtgat acgtccatgt agtctacttt
    66841 atcaatagat acttctaagt tttcactttg agcacgagcc ataacaacgt cttgagcaaa
    66901 tgttccatct tcattcaatg ggctgtttgc ttgggctacg atgtaatggt cttcgatatc
    66961 agctgtcaag tagtcgattt ggtcagtaac acgacctgtt tcacggtcta cacgacgata
    67021 aggtgtttcg ataaatccga atttatttac tttcgcataa ctggacaaac tattgatcaa
    67081 cccgatgttt gggccttcag gagtttcgat cggacacata cggccatagt gggagtagtg
    67141 aacgtcacga acttcataac cggcgcggtc acgagtcaat ccgccaggtc ctaaggcgaa
    67201 aagacgacgt ttgtgtgtca attcgccaag agggtttgtt tgatccatga actgtgacaa
    67261 ctgagaagaa ccaaagaatt ctttgatact tgccacaact ggacggatat tgatcaattg
    67321 ttgaggtgtc aatgtttcag tatcttggat cgacattctt tcacgaacca cacgttccat
    67381 acgtgctagc ccgatacgga attggttttg taaaagttca ccgactgaac ggatacgacg
    67441 atttcctaag tggtcgatat catcgacatt gccgatacct tccatcaagt tcaagaaata
    67501 gctcattgaa gcaatgatgt cggctggacg aaccgttttt acagctgctt ctggatagcc
    67561 gtttccgatc acgtttactt cacgttcagg gtctcttggt gaaaatactt tgatgacttg
    67621 gacagtcatt ggatctgtga ccacaccgtc ttctgatgga tagtaagtca ctgaatttag
    67681 gccattatca atgaaaggag ctagtgtttc catgacttgg tgagtcagaa ctgttccttt
    67741 ttcaacgatg atctcgcctg tttctggatc aactaatgtt tcagctaatg tcagattcaa
    67801 tagacgtgtt ttcaaatcta attttttgtt tactttgtaa cgaccaacgt ttgctaagtc
    67861 gtaacgtttt ggatcgaaga aacgagcatt cagcaagtta cgtgagctgt ctgctgtttt
    67921 tggttcgcct ggacgcaaac gttcgtaaac gtctttcaaa ccttcttctg ttcttgagtc
    67981 gcttgcgttt ttatgcaagt ctttttcgac tgtattgcgt aatgtttcgc tgtcgccgaa
    68041 gatttcaaag atcgtatcat cggaaccaaa tcctaacgca cgaactaata cggttaaagg
    68101 aatcttacgt gtacggtcga tacgtacata agagatgtct tttgcatcag tttccatttc
    68161 tagccaagct ccacggttag ggataacagt agaaccgaat ccttcttttc cgtttttgtc
    68221 gacttttcca tggaaataga cacctggtga acggactaac tgagaaacga ttactcgctc
    68281 tgccccgttg atgatgaatg ttccttgttc tgtcattaat gggaaatcac cgaagaatac
    68341 ttcttgtgct ttgatttcgc cagtctcgcg gtttgtcaaa cgcaatgtta catgtaatgg
    68401 tgcagagtag tttgcatcat gcgcacgagc ttctgctact gtatactttg gttctttcaa
    68461 ttcataatct acaaattcca aagatagatt gccattgaag tcatcgattg gcaaaatgtc
    68521 ttcaaacatt tctctaagtc cctcatctaa gaaccattgg taagagtctg tttgaatttc
    68581 gatcaaattt ggtaattcca acacttcact gattcttgcg aaacttctac gttcgcgatg
    68641 ttttccgtat tttactacgt gtccagccaa gctcttcacc cctctaaaat gtcattcaaa
    68701 aagactaccc gatcaattgt tacaataata tttcaaatat tatttttagg taacaacaga
    68761 cattttttgc ggcttttagg caaaaaaaaa ccaaaaatag aacattctct tgaaacctta
    68821 cttcgtgagc ttctactttt gtttccttat attaaagccg aaacggacaa tatttcgttt
    68881 ctgccttttc ttcatcagat agtttttgca acttcatata ctacacttat tttctataaa
    68941 agtcaacact tcctggcgtt tcttctgctt tttcgcaaca ttttcttaat gttttcaatt
    69001 ttatgttttc aattatctga caattcttaa ttgacagacc tttttatctc ggttatactt
    69061 tagaaaattc attttgtgga ggaacttcta tgcgaaccaa catcaaccaa atcgcaccaa
    69121 cacaactgaa taacttttac tttagctact ttagataggt ttgtattcat catgatggat
    69181 acaaacgtta aacgacagtt tgtatctatg atggctaaag aactttgtat tgcagcaaaa
    69241 agccacgtag acaaaatgct aagtggctga gcagtgaaaa tacaaagtaa aagtatcaag
    69301 cattctactt tttcaattta ttttccgact tttcaatcca tttggacatt ttgtctgaat
    69361 ggattttttg tttcccaaaa ttaaggagga aaaagaaatg aaaaaaaata taatcatcgg
    69421 attaggcgct gccctgctac tagctttagg aggttgcgca caaaaagaca attccgcaga
    69481 ggcatcagat ggacaaaaaa caattggcgt attgcaactt gtacaacata actcgttaga
    69541 tgctgcctat aaaggattca aagaaggatt agcagaagaa gggtataaag aaggcgataa
    69601 tctaacaatc gattatcaaa atgcccaaaa caatcaagac aacctgaaaa gtatgagtga
    69661 gaaactcgtc aaagaagatc ctgatttgct acttggaatc gccactccag cagcacaatc
    69721 tttattaaat gaaacaacca ctatcccgat gactgtcaca gcggtcacag acttggaaca
    69781 agcccattta gtcacatcca atgaaaaacc tggcggcaat gtgactggca cgacagatat
    69841 ggtgccaatc gaaaaacaaa tcggcttact gttaaatatc gtgccagacg ccaaaacaat
    69901 cggcatcatg tataacaacg gtgaagcaaa ctctaagatc caagctgatt tggcagaaaa
    69961 agaattgaaa aaagcgggcg tcaaagtcaa agtactgaca gcaaattcca caaatgatgt
    70021 ccaacaagtg acgaaaagtc tagctaaaga tgtagatgga atctatattc ctactgataa
    70081 cacgttcgca agtgcggcaa gtgttgtcgg tgaagtcgca aaagaaacaa aaacacctgt
    70141 cgttgctggc gcagttgatc aagtcaaaga cggcggtcta gcaacagtag gaatcgacta
    70201 cgaaagcttg ggcaaacaaa cagggatcat ggcagcaaaa atcttagacg gcaagaatcc
    70261 aagtgaactt cctgtcgaaa cagcgaatga tttggaactg tatgtcaata aagacatggc
    70321 caaagcatta ggcatcaatc cagacagcat caaagaagct gaataaaaca caggaggatt
    70381 ctcatgacaa atttgctctc tcttttctta tcatctgcat cgcaaggggt cttatgggcc
    70441 ctacttgcga ttggtgtata cgtcactttc cgtatcttgg acattgccga cttgactgct
    70501 gaaggaagct ttcctttagg tgcagggatc gcggcagtaa gtattacaaa tggctatcat
    70561 ccattgacag cttgtcttct aggcttttta gggagtgcgg cagcagggct tgtttccgga
    70621 ctgcttcaca caaaattgaa aattcccgcc cttcttgcag ggatcatcac catgactggt
    70681 ttatattctg tcacatcccg tgtgatgggt gcgccgaaca tctctttatt gggtcagcca
    70741 acgatctttc attgggtcga gtcattcggc ataacaaaag acaacgctgt actgatcgtc
    70801 ggtctgcttt ttgctttgat cgttgtatgt ttacttgttt tgttcttacg tacagaaaca
    70861 ggacttgcta ttcgtgcaac tggcgataat ctggcaatga gcgaagcaaa cgggatcaac
    70921 acagataata tgaagatcat cggttatatg atttctaatg gatgcattgc tctttctggc
    70981 tccttgcttg cgcaaaacaa cggctttgct gatttaaatt ctggtattgg aacgatcgta
    71041 attggacttg cttctattat catcgcagaa gttttgttac gtaaccagcc actatttctc
    71101 cgtctcttga ctgtcgtttt aggtgcggtc atttatcgtt ttattttagc gttagtcttc
    71161 gaactgaatg ttgaaccaag tgattcgaaa cttgcttctg ctttcgtgct agtgatctgt
    71221 ctttctttcc cgcagatcca gcaaaaattc catttacctc aaaaaaagaa aggcggtagt
    71281 gtcaaatgaa tgacgtctta acattggaaa atctccatca tacctttgaa aaaggaacga
    71341 tcaacgaaaa tcatgtcctg aaaggcatta atctttcctt agatcccggc gacttcgtga
    71401 cgatcatcgg tggaaatggg gctggtaaat ctactttgct gaacagcatc gccggtacat
    71461 tttctgtcga tcagggtcaa attttattga atggaaaaaa tatcacgaaa aaatctgttg
    71521 tcgaacgttc gaaatccatc agtcgcgtat tccaagatcc taaactaggg acagccgttc
    71581 gtttaacggt agaagaaaat cttgctcttg ctatgaaacg aggaaaaaaa cgcggcttct
    71641 tccgtggtgt caaaccacaa gaccgaacat ttttcaaaga ccagctggtt cggctaaatt
    71701 tggggttgga aaatcgttta tcctcagaaa tcggtttgct gtctggagga caacgtcaag
    71761 ctattacgtt attgatggcc acattacagc gtccagaact gatcttatta gatgaacaca
    71821 ctgcagcgct tgaccctgct acttccaaaa cggtgatgga attgacagaa aagctgatca
    71881 ctgagcagaa tctcactgct tttatggtca ctcatgacat ggaagacgcg atccgctatg
    71941 ggagtcgact gatcatgctg catcaaggaa ggatcgtcgt agatatccag caagaggaaa
    72001 aacagcagct cacagtgccc caattattag cgttgttcaa acaaaacagc ggcacggcat
    72061 taaaagacga tcaagtactt ttatcttcat aatcagaaag aggatgggac aaaaaatgaa
    72121 cgcccaccct cttctttttt ctctttcctt ctttcgtttt tgctttatgt atcaaccgtt
    72181 gtttcttcga aaactatttt gttctctcct tcttcctgat agaatggatg ggaaaggagc
    72241 ttgatgccat gacaacgaaa gacaaggtac ttcaattatt gaaaaagaca ccagattttc
    72301 tttccggaga aaagttggca cagcaactgg aagtttcccg gacaagtatt tggaaagcca
    72361 tcaaagaatt ggaaaaggca ggctatcgtt ttgagcacgg gcctacaggg tatcgttacc
    72421 tgccctctga cgtactagat gcaaaagaaa tccagcaaga gctacggtcg tttattcctg
    72481 atttgaaagt acaaacgatg ttgacttctg aatctacgat gaaagatgcc aaactggcag
    72541 cagctcaagg agattctgtt tcgaagttat ttgttgctga tacacaagaa caagctcgtg
    72601 gacgttttgg acggcctttt ttcgctgaac ctggacgagg aatctacatg agtctcttgc
    72661 tccatccaga caaacggttt gatgaattgc ctcaatatac gatcatcgca gccagtgcct
    72721 gtgtgaaagc cattgaatct gtaaccggtc gttctgcttc gatcaaatgg gtcaatgata
    72781 tctacatgga tggaaaaaaa gtctgtggga ttttatctga agcagtcagt gatatggaaa
    72841 gcggcaggat cagtcatatc atcattggga tcgggcttaa tttttctgtt cctcaaaatc
    72901 attttccagc tgatctccaa gaaaaagcca tctctgtctt tcccgacgga caagctagtg
    72961 tcacaaggaa tcagctaatc agcaaaatct ggcaagaatt gttcacttat ctttctcacc
    73021 cagaaaaagc gttggacttc tataaagaaa aatcattcgt attgggaaaa accgtgtcgt
    73081 tcaatcaaaa aggaacgact tatgtcggtc ttgcaaaaga aatcggtgat catggcgaac
    73141 tgatcgtcca aacaaatgaa cagaagatga gtttgtcttc tggcgaaatc agtctcacat
    73201 ctatccgtac gcaataatta tcagatttca caaaaggaca cctgatctca tacagtgtcc
    73261 ttttttctga attctcttca aaagactctc cttattctat cagctgacag tttctctatc
    73321 ctctagaaaa aggtattcta aaaatatcta taaagcatgg tacactttct ttaaatgaat
    73381 caatgcaaaa aacaagagag tcatcagttt acacgatcaa aagagatagc aggccgcttc
    73441 ctttttcaat cttatagata gaccatgggt aacgataaaa acaaaaaaga acttgcgact
    73501 tattttgccg taagttcttt tttagctagt gccttaatct cttaatccca acaaacgtct
    73561 cgcatagatc acctgaccag agtgcatagc agcatcatca ataatagaaa cgagacgcat
    73621 tcctcgtgtg actggtggtg tccagttctc gtcaattact tcatctagct cggaaggttc
    73681 cagccttctt aagtaagaaa tagcaaaatc agcagctcct cgcaagtatc ctagcagatc
    73741 ttctatttga ttagcttgga tctgctttgc ttgttccaga ctatgcttcc aatcttgttc
    73801 gttatctgct atcgtcatcg gaaaccggct ttcccagtct tgactatgcc aaattggaga
    73861 agttcctgct aaatcagcaa tctggaaatc taattctcga gcggtatgcc aagccagcca
    73921 agtcattgat ttgatctgcg gggctctatc ttccactgga aaacgattgg cctcctcaat
    73981 agagacgcct tcaaacaaac gttcaaaccg atcgtatgcc cgatccacac tctcgcatag
    74041 catatctaaa taatccattt attttcctcc tttttattta tcctacttac tttttcctaa
    74101 ttctaggata cctacttata tgttactaca cacccttatt ttttacactt taacagtcac
    74161 catcatcaat agtttggaga ttgaaagaaa aagatagtgt cgaactatca attgaacaag
    74221 aagcaacaat atgaacgttt cattaatatt ctttaaataa acaatgattt ttcaaacgaa
    74281 cagtttaaga ctaggagaaa aagagtataa taggaaaatg tttgaaagga aaggaagggg
    74341 aaaaatgaaa aaaagggcaa gtttactagt cctagttgct ttgttgttca atatcttttc
    74401 gtatggtgtg gccgtttcag cggaaacata cattcctaaa gaccctggga atatttataa
    74461 tgatctaact ggtaactatg gcttgttagg aattgctagt caattccacg tatttgctaa
    74521 aaataagaca actgtgaatg cacatacaga cggaaatata gcaacacatg aacttgatgc
    74581 aaaaaataat tttggtacag agcttcatga aggtttattg aaccaagaaa taaattatat
    74641 acaaaaaact gattctttcg ctaattcttc aggcatacct acaggtagca caagaatgaa
    74701 taaatttgtc gttggcagta acgtggatgt agcacttcaa gatggtcatc ctacagtcaa
    74761 tggatccagg cttgatcact taactccaga tgatttttat aaagatcgtg ctgggcatga
    74821 atatattgat ttcgagcagg aatttgctaa attgaatgta gcagcaaatg atcttgcaac
    74881 gatcactcca gctaaaacat atactgctgc agattttcca gacatgaaca atcggacaat
    74941 cgatttaact gatttatcag ataccgggtt tttattggta aatatcgatg cagaagtgtt
    75001 aacgatgaat acgccacttc aaatcattaa tccaaatgat caagtagttg tatttaatgt
    75061 catcaacagt tcttctgcat tgaacgtaca gtcaccaatc aaatacaatg atcgttcaaa
    75121 tcatgaaaca gaagattttt cggatgcgaa tatctcttgg aattttggaa atgagatgac
    75181 tgatttgaca atcagtgctc cttttcaagg aacaatcctt gcgcctaatg ctactatccg
    75241 cattactcaa aaccaagacg gaacgattat aggaacaaat gtgattttag atgcagctac
    75301 caatcgttgg gatcctaacg aaatatttat cagcgacaat ggtacagata ctacagacac
    75361 aagcgacagt acagatacat ctaccacaag tgatagctca gattcatcaa cttcaagcga
    75421 cagtacagat actacctcta ccacaagtga tagcacggat acatcagctt caagcgacag
    75481 tacagatact acctctacca caagtgatag cacggacaca tcagcttcaa gtgacagtac
    75541 agatactacc tctaccacaa gtgacagcac ggacacgtca gcttcaagcg acagtacaga
    75601 tactacctct accacaagtg atagcacgga cacatcagct tcaagtgaca gtacagatac
    75661 tacctctacc acaagtgata gcacggacac gtcagcttca agcgacagta cggatacatc
    75721 taccacaaca agtgatagca cggacacgtc agcttcaagt gacagtacag atactacctc
    75781 taccacaagt gatagctcag attcatctac cactacaagt gatagcacgg acacgtcagc
    75841 ttcaagtgac agtacagata catcctctac cacaagtgat agctcagatt catcaacttc
    75901 aagcgatagt acagacacgt cgtctaccac aagcgataca cgtcatgcaa gtgtctcctt
    75961 ctcaaaaaca agttcggata acaggacgaa ctttaactta actaataaaa caagcaatga
    76021 caatggaaac aaatcaaaaa gagcacttcc taaaactgga agtcaatcga ataattggat
    76081 aacactcgca ggcgttatat tacttgtaat cggtttaaga atcactttta tgagttataa
    76141 gaaatcgaaa aggtaaaaaa atattcaaga taaaaaagag caacgtcgct aacggacgtt
    76201 gctctttatt tttgcttttt atcataaata caagaactac aattcaattt gtcaaaaaac
    76261 acgtagattt ccttctgaga aatttattta cgtatcgaac ctttccctat tcagtctttg
    76321 cgatccaaaa tcagttgggt aagggaaaag agattctctt ttgttcgaag agaggtggca
    76381 ggtaatttct ttatttcctt caaagccttt tctgtgtaag aggccgctaa cttcctagct
    76441 tcttccacgc ctcctgtatg ttcaacgatt ttgcgtacgg cgtcgacatc ttcttctgtc
    76501 attgccgctt tcttctctaa ataaggtagt agctttggtt tgtttttttg caaagagtag
    76561 atcaacggta aagaatagac cccttgacgc atgtcttcta gtacaggttt gccgatttcc
    76621 tggctctctt ttgtataatc taaaatatca tcgataatct gaaaggccat cccgatagaa
    76681 agtccgatat ctcctgcttt ttttgcgaag cgctcgcttg ttccactttc aaaagcgcca
    76741 acagaacaac ttaattggaa cagttcagct gtcttacctg aaatattttc caaatattct
    76801 tttacagaaa gttcataatt atagcgatca tccatctgac ctaattcgcc attcaatact
    76861 ttttccatac tgcgagaatt caattggaga cttttcaagg aagtggagta atcagacaat
    76921 agtttaaaac agcagacaaa taaatagtct cctgcataga cagaaacgac attaccaaac
    76981 tgactacgga tattaggctg accacgtcgc agatccgctt catcaacgat atcatcatgg
    77041 atcagtgtgg ccgtatggag catttcgata gaagctgcca aagcgatggc tttgtctcga
    77101 tcttgctctg gtccaaattg tgagaacaat agctgatagg caggacgcaa cagctttccg
    77161 ccggcatgga tcgtttcttt gattgcttgt tcgacaggtt tgtttttcag gcggacagtt
    77221 tcttccatcc gttttagtgt ttctgtcaat tctttactta aagcaggata gttttcccac
    77281 attggatgta gcttcataaa aaaactcctt gtgtgacgat tattttttgg taaacattgg
    77341 gctccatttt tgtttggttc cctgctcata atctttttgg aatcgttgaa gtgtctgcac
    77401 atgtcgtaaa agataattcg ctgcgatccc gattgcaatc cctgataaaa tccctaaaac
    77461 tgaaaggact ggcaagtaca acatgactgt ccatgattgt gcaatgaaag aagccatcaa
    77521 aagctgtccg acattatgca tgaaaccgcc ggccgcacta attccgatga tactgacacg
    77581 ttttggtcct aattgcttga ccaataacat tccaaaataa ctaagcaaag caccactcat
    77641 actataaagg aatgtggaaa tcgttccgcc tagcaaagta gtcaggaata gtcgtagcca
    77701 aagtagtaag aagctgtctc gttttttcat ggtaaaaatg gcaacgatcg tgattagatt
    77761 ggctaagcct agttttgcac caggcgcaaa agaaaaagga taagggatca tattttccaa
    77821 taaaccaatg atcactcctt gtgcaacaag tagcgaaata taaatcattt tttgtaattt
    77881 actcatggtg tgtgaaggtc taataaatca gactgtcttc gtcacctcca tctgttgaac
    77941 ggacttcgat cactaattta tgtggcaaac agacgatggt ttcgccattt ttcgttgccc
    78001 agcctcgacg tacgcagatc tggtcatcgc aatctgcttc ttttatccgt actcgatcgc
    78061 catctatctc gatcaagtta taatctccgt gttcatcttt gtaagtatat gtgttgctct
    78121 cttctccagc catcaaaggg aatgttttga tttctgtgcc atccacacgc agtaccgctt
    78181 ctttttctgc tgttgcggtg ttttgctgaa gaccaaaaat catgactggt aaaaaagaaa
    78241 gaacagtcaa aagcaaaata ataaaaacat cccaaggttt gagcagactt ttttcagcaa
    78301 attctttaag gctcattttt gttctccttt ttccagatta actcacccaa ttttagcata
    78361 aaaacaagag gttgtgacac ctgtgtcttg ctttgagtaa taagaacgaa gaatagaaaa
    78421 cagctttcca tgttttctaa ttctttgggc ttattaccga gaagcagcag gtggaacacc
    78481 gtttataaca agaggttgtg acagaagtgg gcaacttcaa gaaataagaa ggaatttacg
    78541 aaaattactt ttcaagtttt tgtgaaattt cggcttattt ttcgaagaag ctacttctgg
    78601 aacaccgttt ataacaagag gttgtaacag aggttgtgac acctgtgtct tgctcatgga
    78661 ggcttatctc gggcatctta ttcctttaat tttacataaa aaggaggctg tgacggtttg
    78721 tctcagcccc tttctattga aatcttgcat tcaaataacg ttctttatct atttatttct
    78781 tgccgtactg ggaacttggt ctaccgtacc accaattacc tagtgtacgt tgtagccatg
    78841 gaattaccca gcgatccaac ccaatcgcac gtccggaacc gttcatcaat gcgaaagcaa
    78901 caaaaatgaa ccaaatgttt acccagtaaa acatgcctga taagcagaac gtgatcacca
    78961 atacaatcgt tgtcgcactg catagccatg tgaataatcc agcaatcaat gctaatgcca
    79021 aggcaatttc aaagaatacc atgaattttt ggaagaacat tgctacatca ttgtttggca
    79081 tgatcacttg catgatcttt gtgaaccagt ctggtgactt ctcaatcaca gccattggtt
    79141 cttcaccgta tgcataactc aaaccaaaat gtgcagcttg agtcgctgct tctccggcac
    79201 ttgcccctgc tccgctggca gctgtggttg catcaccagc agcagaagca ccactggcaa
    79261 catctgttac attgtattcc catgtccaag ggaacacact gtttccagtg aaccatgatc
    79321 cttcaccaaa ccaagtactt ggtttgaaca cttcaccatt cccaatgatt tttttggaag
    79381 cttcaacgaa ccaaactaaa ccatagaaaa tacgaagtgg cacactccat aagacattgc
    79441 cgtaacgaga agaatgtcct cgagtcacgt tgcgatcatc tttgatatgg aaaaactcat
    79501 gcattaaata ttggaacata taataaccag aacgaatatc aaagaagtat ttcaaattca
    79561 cgatatgttt cattacgata gctaaaaatc cgcttaaatg gatcttatca aataggttag
    79621 ctacccccca tttggcacca atagaaacca taaatccttg atagtttcct ttaaatttat
    79681 gcttttctcc gcctttgatc gaagccacga tattcgctgc ggctgtgtgt cctgtttgtt
    79741 cagcagcttg aacgatctgc ggtgtcggtg ttcctgggaa ttcttcataa aagactaaat
    79801 caccaatgat atagatgttt ttatcttcgt agccttttgc ctgcatatat tcattggcga
    79861 tcaaccgctg tccgcgtgct gattctaatc caaagtcagc agcgtcagaa gttcctttga
    79921 caccagctgt ccaaatcagt gtgtgagtcg gaatgttgcg tccgtctttc aatttgatat
    79981 gatcagcagc cacttctacg attggtgcat tcaataataa ttccacgttg tgcttacgca
    80041 aatagcgttc agcttttgca gcatcatttc gatccaacat attcaagatc gtcggcattg
    80101 cctctacgac catcagtgtg atttcgtttg gatctaattt ataatctttg gctaggcgat
    80161 ttttccagtc gatcagttcc ccaatcattt caataccggt aaatccagaa ccacagacaa
    80221 cgaaagtcag catggcttta cgcagttcat catctggttc caatgcagct tttgctactg
    80281 tcttctcaat atgttcccga atccttacag aatcttcaaa tgaccaaagg gtgaatccgt
    80341 gtgctttgac accaggtgta ccaaagtcat tcggctctcc gcccattcca aggatcagct
    80401 gatcaaaagg ataggaacct aatttggtct tgacgatttt tcgttcttta tcgataccga
    80461 ttacagtgtc tgtgacaagt tgtacattct tttgacgagc aaacaaatgc tgcagatcgt
    80521 attggattgc ttctggttct acacgtccgc cagctacttc atgcaactcg gtcatcatag
    80581 tatggtacga atgacgatcg atcagagtaa ttgctacatc ttcttttttc agtttctttg
    80641 ccaagtattt tgtagctgaa acaccggcat atcctgctcc tacaacgaca atattttgct
    80701 ttgccattga tcatccgctc cttatagact atctatataa tgaatatatg ataattcttt
    80761 tagtttgata cttattacac aatctccata tattatatag atgttctgtt cttttgtcta
    80821 actccttttg gatttttttc aaattttaaa ataaagcgtt ttttcacgaa atttgctgaa
    80881 agaaaacgtt tgaaatatta catgggttat ttatcaaaaa tagttgactt ataggctaaa
    80941 aagattagaa tgtataatga atcacaaaga aaaattgtgg actagaaatg gaatggtggg
    81001 gtattaaaat gaagaaaaaa cgttttgtaa ctggatttgc cgtattagca ttttcagctc
    81061 tagtgttagg cgcttgcggc gcagatgaca acggaagctc aaactcttct tctgaatcat
    81121 ctacagcaca atcttcgact gcaaaaagca caacagaatc atctgcaaaa gttgtagctg
    81181 gcggagattt gcaagacggc acatataaat tagaagaaaa aaattattca aatggttacc
    81241 gtgcagtctt tgaaatggtt gtaaaagacg gcaaaatcac tgaatcaaaa tatgataacg
    81301 tcaatgaaaa cggcgaatca aaaacaaaag atgcagaata caacaaaaac atggaagcaa
    81361 aatctggcac aaacccagaa aaatacattc ctgagttgaa tgaccaattc ttaaaagcac
    81421 aaagcgcaag cggtgtggaa gtcgtaactg gagctactca ctcatctgaa agcttccaaa
    81481 actacgcaca acaattgatc caagctgctc aagctggtaa cacagataca atcgaaatcg
    81541 acaatggtgc tgatttgaaa gacggcactt acaagcttga agaaaagaac tactctaacg
    81601 gctaccgtgt gcaattcgaa atgacagttg ctggcggcaa agtaactgaa tcaaactttg
    81661 attatatcga caaagacggt aaatcaaaac aagatgatac agaatataat gaaaatatga
    81721 aagcaaaaag cggtacagaa ccaaaaactt acatccctac tctgaacgac gaattcgtca
    81781 aagcaatggg cgaagaagat ggctcacctg ctaatgtaga agttgttaca ggtgctacac
    81841 acagctcaca ttcattcatc atgtacgcac aacaattagt gaatgcagct gaaaaaggcg
    81901 acactcaaac aatcgaagta gataatatcg taacagaaaa ataatcacat aatcatacta
    81961 ataaaagttg gagggtggga cgatagccag attaggcagt cgtctcacct ttcaaaatga
    82021 agagaggaaa aagatgcgga aaaaactact attttcctta atcacactgg gcatctcttt
    82081 tatggtgcta actggctgca gcaactcagc aaataaaaca accactgaaa gttcagcagc
    82141 taccaagata ttgaaagatc catattctga tgaacagttc ttgttaggga cttacgttcg
    82201 tatccgtgtg tatgatgaag gcaaagaatc agcattgaaa cctgccttcg atcgagtaaa
    82261 agaacttggt gataaaatca cgatcaatca aaaaggttct gagatcgatg aagtgaatga
    82321 gcaagctggg atcaaaccag taaaagtttc tgatgacgtc tacacgttag tcaagcgggc
    82381 ctacgaatat agccaagatt ctcaaggcgg attcgatatg gcgattggtg caatcacaca
    82441 attatggcga atcggttttg atgacgccag aaaaccttcc caagaagaaa tcgatcaggc
    82501 attgaaatta gtggattatc ataagatcga actaaatgac aaagaaaaaa ctgtttatct
    82561 aaaagaaaaa ggaatgatca tcgatttagg tgcaatcgcc aaaggttaca ttacggacga
    82621 agtagtgaaa gtcttgaaaa aacaaggagt gaccactgcc atcgttgact tgggcggtaa
    82681 tgtctatgtc ttaggccaca gcccaagagg cgaaaaccaa gactggacag tcggcatcca
    82741 agatccgaac atggctcgcg gatctgtttt aggttctatt aaagaacgga acaaaacatt
    82801 agttacctct ggaatttacg agcgttattt agaagtagat ggcaaaaaat accatcattt
    82861 gtttgatcca aaaacgggtt atccgttcga caatgatatc gcaagtgtca cgatcataac
    82921 agataaatca attgatggtg acgggttgtc tacagcagtc ttttcaatgg gtgtgaaaaa
    82981 aggactggaa tacgtcgaaa gcgaattgaa taacgggacg gaagcgatct tcgtgacaaa
    83041 agacgataaa gtatatgtga ccgatccaat caaagacacc ttcaaattat cggaggactc
    83101 ccattacacg atgggtgacc gttctgaact aaaataagga gtacgaacca tgacactaaa
    83161 aatcttttta gaagtagttg aaatacgaac aaaggtggct agtgtatttc cttttgcggt
    83221 aggggtatta ttctctatcg ctttttttca tgagatacat tggctaaaca cttttttatt
    83281 ttttattgga atgctagttt ttgatttagc gactaccgct atcaataatt acatggatta
    83341 tgaaaaggct cattctgaag tatataagta tgaagaaaat gtcattggcc gcagaaatct
    83401 atctcctgta ttgattcgaa acatgatttt agctatgatt gcatttgttt ttgttatcgg
    83461 cgttattcta acgatcaata cgggttggct tttacttttg atgggattta tctgttgttt
    83521 tattggagta ttctatacat tcggaccgat tcctttatct cgaatgcctt taggggaaat
    83581 tttcagtggg gtgactatgg gccttggaat ttttgccatg gtcgtttatg tcaatacatt
    83641 cggttcagat gtctatgatc tgacagtcaa cttttcatct ggacaatttg ctttggtagg
    83701 aaatctttgg gctatagcag caatcgtatt agcttcctta cccttggtgt ttacgattgc
    83761 caatatcatg ttggctaata atttgcggga tcttgaccgt gatattgaaa atcatcgcta
    83821 tacactagtt ttttatatcg gacgtcctgc gggaacagtc ttattccagc tattgatgta
    83881 tgcttgctat ttcgtgattt taatggggtt gttgagcggt atctatgaat ggccgatctt
    83941 ggtcaccttc ttgaccttgc caattgtgaa gaagcatttg gatcaattca agcaaacgtt
    84001 accccagcct atcagtttca gctattccat caaaaatatg gtcttattca atgccagtta
    84061 tgtattgggg ctattactaa caatcattat gcaagccatt taacagcatg aagaggttgt
    84121 gaaaaaactg ccctgcatca agtaataaga acagccaaat aaaaatagct ccttatattt
    84181 ttcgtttggt tgggcttatt accgcagatg caagcttttg aacaccgttt atcaggaggt
    84241 tgtgaaaaag tcgcttagtt tcgagtatta agaaaaattt tgtgaaaatg gctttccaca
    84301 tttttgcata aatttggctt aataccgaga aactggcttt tgaacaccgt ttatcagagg
    84361 ttgtgaaaaa gtcgcttagt ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac
    84421 atttttgcat aaatttggct taataccgag aaactggctt ttgaacaccg tttatcagag
    84481 gttgtaaaat cagtgttttg tcctgagtat tagagaaaca aatggaaaaa tagttcctca
    84541 tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacacta tttgttcgga
    84601 aaaagtgact aactatgaca caattttttt cacagtccct tttttcactt gatttgattc
    84661 gtaccagcga acttgacgag aactttcttg gtttggtaac tatatggtat tcttttaaca
    84721 tcctcgtttg cttcttctaa tttatttata caaagtcaca cttttttaaa catctgttct
    84781 tcgatacatt tctatttctt ttaaacatcg ataccaatat tttgaactta agagtgcata
    84841 ccaaatggat tcatttactc ttcgtcagtt acgaagataa tcaaaatctc caacttccct
    84901 acttatttcg ttttgagaat tatcgaagca atcttacata aataactaaa aaacaaaaaa
    84961 ccagaaaatc agtatactga ttttctggtt ttacatggtt tgttcaataa aaagctgttg
    85021 gaactgttaa tattaaatta tcgcatcgtt acgaattctt ccgctcctgt tggatggatg
    85081 gctactgtat tgtcaaagtc ttctttagtt gcacccatct tgatagccac ggcaaaacct
    85141 tgcagcatct catcgacacc aacaccaata gcatgtaagc cgacgattct ttcttctttt
    85201 ccgacacaga tcaatttcat ttcgcatttt tggcgataat catttaatgc aaagtacatt
    85261 ggggtaaagc gtgaacgata aactttcaat tcattttcgc catatttttc caatgcttct
    85321 tcttctgtca aaccaattgt tgcaattggt ggatgcgtaa agacgactgt cggaacaagt
    85381 ttatagtcaa gataagaatc tttctttcca ttaaataaac gttctgataa acgtctacca
    85441 gctgcgattg caacaggagt cagatctaat ttaccgatca catcaccaac agcaaaaata
    85501 tgttcatccg ttgtattttg gtatttatct actttgataa accctttttt gtccaattcc
    85561 acatttgtat tttccagacc taatttttcg gtattcggta cacgtccacc ggcaaaaagt
    85621 acacaatcac cagttaaggt ttcaccattt tcaaatagca ccgtatattc gtcattgttt
    85681 ttagtaattt ctttagcaat atgatgtgcg taagttttta ttccagcttc ttggtacatt
    85741 tggatcaaat tgtccgaaag cattttatca aacgttctaa gtggtcgttc ttttcgatat
    85801 gcccacatga cttcactacc taaaccacaa aatacacctg aaagttcagc cgcaatgtat
    85861 ccagcaccta aaacgattgc tctcttaggt aactctgtta attcaaaaaa tccatttgaa
    85921 tcaattgcgt attctccacc aggaatggtc attttacttg cacggcctcc agtagcgatc
    85981 aagattttag gagcacgata ggtttcaccg tttacttcga tcgtttgact atcgataaaa
    86041 gtagcgtaac cttttatagc ctcgacatga ttgctatcta atcctctttg ataagcaccg
    86101 tgtagaaaat caatatattt ttctcgtctt tctactagac cggcgaaatc aacatttttt
    86161 aaatctgctt ggataccgta acttgaggca tctcgttcaa ttgtttccaa aatcgtactt
    86221 gcttgccaca taactttttt aggtacacaa ccgacgttga cacatgttcc gcccaattca
    86281 ttcgcttcaa tcagcaaaac ttttgcgcca tgcatccctg ctctgtttgc tgaagcaata
    86341 ccgccagagc cgccaccaat tacgatgtaa tcatatattt gcattttgtt cctccttatt
    86401 gaagagatca atcaaaacct ttatttaacg atcctttttc tacagaaaac aagtgtaaca
    86461 cttttcttga attttgtatg cgaagatgct taaaacaggg atatatcagc tttttcctta
    86521 tttacgtttt cggatcatat ctccaggttt caccggctgt gcgactggca tagttaaaat
    86581 catcattgga tttggtgctc ggtcaatgga ttcgccttct tcattatgca taacttcaac
    86641 ggtttgactg aaatgactga atcctggacc ataaaattcg atttcatctc ctacagaaaa
    86701 caagtttctc tgacgtatcg tagcaatctg tgttgcctca tcataagata atacttcacc
    86761 gacaaattta tatactggga ttttacgacg ttcaccgaat aattgttcgt tttcagttgg
    86821 tgtattgtag taaaaacctg tagctaattc tcgttgtgct actttccata actcgtcgat
    86881 ccattcttgc ttgcagacat agttttcagg atcttccata taactgtcta cagccgcttt
    86941 atagacattt gacaccgtag atacataatg gatcgatttc attcttcctt cgatcttgaa
    87001 gctgtctacg ccgttttcaa tcaattctgg aatatgttcg atcattgaca tatccactgc
    87061 actcatcgag aattcttctt ccacttcgcc tgtatcagtt aaactgtttc gttcttgacc
    87121 aaaaggcata tcgaacaatc catacttcca gcgacaagat tgagaacatc cgccacggtt
    87181 tgcatcccgc atcgacatat ggttggacaa tgtgcatcga ccagaataag agatacacat
    87241 ggcaccatgg ataaatgctt cgatttcggt atccgtattt ttacgaatct ctgccacttc
    87301 ctccattgaa acttcacgag ctaaaacgac acgttccaac ccttcttctt tccagaattc
    87361 caatgtctca aaattagttg ctgaagcttg agtggataaa tggatcggca gacctggggc
    87421 ttctgtcgca caaatttcga tcaaagctgg atcagaaaca atcactgcag aaataccgac
    87481 atcacgcaaa ctgcggaaaa attcccctgc tccatcttca tttccttcat gggtgaccat
    87541 attagcagca acgtatacct tcgcatcatg ttcttttgca aaagcaactc cttcagccat
    87601 ttcttcataa gtaaaattac ctgcacggct tcttaaacca tatgcattcc cgccaatata
    87661 tactgcatct gctccataat ggatcgcggt ttttaacttt tccagtgttc ctgctggcgc
    87721 taggatttct ggtcgtttca attttctttt tactgtcatt tctttcatca tactccttat
    87781 ttgatagcag aaggatcaat ataaaagaat cctgtatcta attcacggtt ttcaggatgc
    87841 aatttactga tttcgctagt cattttttcc gctttttctt gatcccagct accttctaaa
    87901 atttgttttt ttgcttcggc gaatagtcga gtgatgttta cgaatttttc gcctggagta
    87961 aataatccgt ccaatttcca tgtacagtaa tgatgctgat aaagttcatt caattcattc
    88021 gagagattca gatcattgct ggcaaaaata tgtgtgccat gactatcttc ataaatagaa
    88081 taatgtgtct cttctttttt aggttccgag ataaaaagac ctctttcacg atctttttgt
    88141 tcgtcttgtt tcgtatagtt atagtaattc tgtagcagtg gacgtttgga ttgatggatg
    88201 catgtagcac catacacaag ggtttctaca ggaatatcga gtttttcttc catcgccttc
    88261 atctcttcaa aaggaacttc acgagcaagt actgctccaa ctgcgccttt tttcgcccag
    88321 aaattgattt gacgtgcgct cgttactaat gtttcagcat cataaatata cggtatacgc
    88381 aattcaggat tttttttcat cgtataaata atacctgtat caccaactgt gatcacatct
    88441 acgtttattt cttttaaaaa agccaaatat tcaggtacat ttttcatttt ttcaggatga
    88501 atgatcccat ttacagcaat attcgctttt ttaccatact tgtgtgctaa ttctaccaat
    88561 tgtcgctgtt cttctcgtgt aaatgaagca ggcagacgca atccaaattg ctcttcaccg
    88621 aaatatagtg tatctgcacc tgcagcaagc aactgttctg cttgttcaat agtttctact
    88681 gtggttatga gttcgatcat aattttctcc tcctacaact tcataatagt agcatagctc
    88741 taaaaacttt ccaatacttc ttctatttaa agtcggattt ttgaaaatta tttcacaaaa
    88801 aatcaaaata aagttcgata tattctgtcc aaatataaaa agagattgtg acaaaaatct
    88861 tgtcacaacc tcttaatcaa gtcttactat tataaaaatt cagctacaca ggccaagtaa
    88921 ctatagggaa cctactgttt cctttttagg tccgcgaaca ttcaatgtga tcttaccttt
    88981 tgaagcacct actgttacgt ggtcacctaa acgaatttct ccgccaagca aagcctcgct
    89041 caatcgatct tcaatttctt tttgaagtgc gcgacggatt ggacgtgcac catattcagg
    89101 atcaaatcca gctttcccga tcacatcgat tgcagatggt gtgattttca cttgaatatc
    89161 ttgttctttc aatcgtttga taatcgcttt gctcatgatt tggacgattg tatggatttc
    89221 atctttactc aatgaatgga agacgacagt ctcatcgatt cgattcaaga attcaggtcg
    89281 gaaagctttc tttaactctt ctaagatacg tttttgcatg gctttgtgat ctttagtaac
    89341 atcttggaca ttgaatccga catttttttc ttctcgaatt tgtgtcgctc cgatatttga
    89401 agtcataatc atgattgtat ttctaaagtc cacttttcta cctttagaat ctgttaaatg
    89461 accatcatcc aatacttgca gaagtaaatt gaaaacgtct ggatgtgctt tctccacttc
    89521 atctaagaga atcactgaat atggtttttg acgaattttt tctgtcaact gtccaccttc
    89581 atcataccct acgtatcctg gaggagaccc gattaatcgg cttgtactgt atttttccat
    89641 aaattctgac atatcaacac ggatcagggc atcttcactt ccaaacatga cttctgaaag
    89701 tgctttggcc aattctgttt ttccgacacc agttggtcca aggaacatga atgaaccaat
    89761 tggacgatca ggatctttca atccgcttcg tgcacggcgg atcgcacgtg aaactgcttt
    89821 gacagcctca tcttgaccaa cgacacgttc atgcagaagt ccttccagtt ctaacaagcg
    89881 ttcgctttct tttttctcca actgctgtag agggacacca gtccactccg atacaactgt
    89941 agcaacatct tcttctgtta cacgatcaga ataaccttgc tcctgttttg cttcaattgc
    90001 agaaactttt tgcagctttt tacgtagtgc tttttcttgt ctgcgtaatt gagcagcatt
    90061 ttcaaagtct tgtttttgga tcgctgcttc cttttcttgt actagttcat cgatttctag
    90121 tttgatcaca gttgattttg ttaagtgatc ggtttgatcc aaacggactt tcgctgctga
    90181 ttcatcgatc aaatcaattg ctttatcggg tagttgacga gaagtgatat aacgaacaga
    90241 aagattgact gctgctcgta cagcttcatc tgtgatctcc actccatggt gctcttcata
    90301 tcttgtacgt aatccttgaa gaatcacttc tgcttcttca ggagttggct catctacttg
    90361 aatgcgagca aaacgtcgct ctaatgcaga atctttttcg atatattttt gatattcatc
    90421 tagggtcgtt gctccgatcg tttgtaattc tcctcgagct aacgccggtt tcaagatatt
    90481 cgaagcatca attgctcctt ctgctccacc tgcaccaatt aaggtatgca attcatcaat
    90541 gaataagatt acttgaccat cattatagat ttcgtcgatg acctttttca ttcgatcttc
    90601 aaattcaccg cgatatttcg taccagcaac caaagatccc atatcaagca tcatcaggcg
    90661 cttttcttgc atgtcttctg gcacttcacc taaaatgatt ttttgagcta acccttcagc
    90721 aatggctgtt ttgcctacac caggttcacc caccagtaca gggttattct ttgtccgtcg
    90781 gctaagaatc tggataagcc gtttcacttc tctcgaacga ccaacaactg ggtccagctt
    90841 gttttctttt gctaatttcg tcaaatcacg tgctaatgaa tctagcgtag gtgttccttg
    90901 cggtgtttgc cgtttatctt gtacatttac atttctacga cgattcattc cttttccagc
    90961 agaatcacca gctagcccca ttttttgttt cagaacttga cgggcttttg aaaggctgat
    91021 acctaagttg atcatgattc gagtagccat gatactttca tcttttaata agctcatcaa
    91081 aatatgttct gttccaactt tttgagaacc agttttcttc acttcgctgc tagctaaagc
    91141 aaaaacttgt ttcattcttg gtgaatatgg aagaaagact cctttagggt aagaacggat
    91201 accaccataa ccaatcagat gttcaatttc ttcataaatt tccgtttcat tcaaatccat
    91261 ttcacgtaat acttttccag caattccatt ttgctcgacc actaaggcta gtaaaacatg
    91321 ttctgaacta actgattgat gtttcaaccg ttttgcttct tcttgtgcaa tttctaatac
    91381 tgcttgggct ctttcagtaa aaagttcttc catctaatct cacttcccat cttcataact
    91441 taaacgttcc agaaatgctc ggagaatccg agcacgtgta tgatcttcat attcattgaa
    91501 attcaatgtg ttttttgcaa ttgcactcaa catcaagttt ccttcttttt ttgtaattat
    91561 ttggtcttca taaagttttt gaataatagc aaaagcattt ttctcactga ttgtatcatc
    91621 aaataactga tttatctgct caagtaattg ttttttatct gaaatcctta cttttgcaat
    91681 tcgtatataa ccaccaccac cacgtttgct ttctactaga taaccacgtt ggatggtaaa
    91741 acgggtatta atcacatagt tgatttgtga aggaacacag ttaaagaggt ctgccatttc
    91801 aatccttcga atctcgatca tttcactatt ttccagaatt ttctttatat atgattcaat
    91861 taaatccgag gtattctgat gtgccatctt attcattccc tttgactaat attgacctta
    91921 attataacga atttgataat agaaagaaag aagaacgctt tttgttaaat aaatccttta
    91981 gaatcaacaa aaaaaaatac ggaatatact attccgtatc gacgcgccca agaggagtcg
    92041 aacccctaac cttttgatcc gtagtcaaac actctatcca gttgagctat gggcgcatat
    92101 tcaatttaaa aaaattataa atcatttgaa aacaaaaagc aagataaaaa aaatcgggaa
    92161 gacaggattc gaacctgcga ccccttggtc ccaaaccaag tgctctacca agctgagcta
    92221 cttcccgttt aaaaaataaa aaagac
//
LOCUS       DAPBCF010000006        91035 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.006, whole genome shotgun sequence.
ACCESSION   DAPBCF010000006 DAPBCF010000000
VERSION     DAPBCF010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 91035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.006"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            103..621
                     /locus_tag="RD508_000507"
     CDS             103..621
                     /locus_tag="RD508_000507"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDT7735132.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            749..1432
                     /locus_tag="RD508_000508"
     CDS             749..1432
                     /locus_tag="RD508_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HDT7735133.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1741..1814
                     /locus_tag="RD508_000509"
     tRNA            1741..1814
                     /locus_tag="RD508_000509"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1775..1777,aa:Arg,seq:tct)
     gene            1973..2332
                     /locus_tag="RD508_000510"
     CDS             1973..2332
                     /locus_tag="RD508_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HDT7735134.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2455..4086
                     /locus_tag="RD508_000511"
     CDS             2455..4086
                     /locus_tag="RD508_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HDT7735135.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4148..4789)
                     /locus_tag="RD508_000512"
     CDS             complement(4148..4789)
                     /locus_tag="RD508_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDT7735136.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    4975..5051
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5071..5379
                     /gene="rplU"
                     /locus_tag="RD508_000513"
     CDS             5071..5379
                     /gene="rplU"
                     /locus_tag="RD508_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDT7735137.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5406..5750
                     /locus_tag="RD508_000514"
     CDS             5406..5750
                     /locus_tag="RD508_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HDT7735138.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5763..6056
                     /gene="rpmA"
                     /locus_tag="RD508_000515"
     CDS             5763..6056
                     /gene="rpmA"
                     /locus_tag="RD508_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDT7735139.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6490..9297
                     /locus_tag="RD508_000516"
     CDS             6490..9297
                     /locus_tag="RD508_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7735140.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9488..9979
                     /locus_tag="RD508_000517"
     CDS             9488..9979
                     /locus_tag="RD508_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7735141.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10082..11071
                     /gene="manX"
                     /locus_tag="RD508_000518"
     CDS             10082..11071
                     /gene="manX"
                     /locus_tag="RD508_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HDT7735142.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11104..11907
                     /locus_tag="RD508_000519"
     CDS             11104..11907
                     /locus_tag="RD508_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HDT7735143.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11928..12842
                     /locus_tag="RD508_000520"
     CDS             11928..12842
                     /locus_tag="RD508_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HDT7735144.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12925..13299
                     /locus_tag="RD508_000521"
     CDS             12925..13299
                     /locus_tag="RD508_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HDT7735145.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13438..13683
                     /locus_tag="RD508_000522"
     CDS             13438..13683
                     /locus_tag="RD508_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7735146.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13855..14919
                     /locus_tag="RD508_000523"
     CDS             13855..14919
                     /locus_tag="RD508_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDT7735147.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15165..15590
                     /locus_tag="RD508_000524"
     CDS             15165..15590
                     /locus_tag="RD508_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7735148.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15583..16032
                     /gene="nusB"
                     /locus_tag="RD508_000525"
     CDS             15583..16032
                     /gene="nusB"
                     /locus_tag="RD508_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDT7735149.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16129..16983
                     /locus_tag="RD508_000526"
     CDS             16129..16983
                     /locus_tag="RD508_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HDT7735150.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            16984..18321
                     /locus_tag="RD508_000527"
     CDS             16984..18321
                     /locus_tag="RD508_000527"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDT7735151.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18326..18550
                     /locus_tag="RD508_000528"
     CDS             18326..18550
                     /locus_tag="RD508_000528"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDT7735152.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18552..19442
                     /locus_tag="RD508_000529"
     CDS             18552..19442
                     /locus_tag="RD508_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDT7735153.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19451..20269
                     /locus_tag="RD508_000530"
     CDS             19451..20269
                     /locus_tag="RD508_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HDT7735154.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20376..20825
                     /locus_tag="RD508_000531"
     CDS             20376..20825
                     /locus_tag="RD508_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HDT7735155.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20843..22525
                     /gene="recN"
                     /locus_tag="RD508_000532"
     CDS             20843..22525
                     /gene="recN"
                     /locus_tag="RD508_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDT7735156.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22580..22696)
                     /locus_tag="RD508_000533"
     CDS             complement(22580..22696)
                     /locus_tag="RD508_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HDT7735157.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22769..23725)
                     /locus_tag="RD508_000534"
     CDS             complement(22769..23725)
                     /locus_tag="RD508_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDT7735158.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23896..24264
                     /locus_tag="RD508_000535"
     CDS             23896..24264
                     /locus_tag="RD508_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HDT7735159.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24434..24865
                     /gene="mraZ"
                     /locus_tag="RD508_000536"
     CDS             24434..24865
                     /gene="mraZ"
                     /locus_tag="RD508_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HDT7735160.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24886..25845
                     /gene="rsmH"
                     /locus_tag="RD508_000537"
     CDS             24886..25845
                     /gene="rsmH"
                     /locus_tag="RD508_000537"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDT7735161.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25850..26251
                     /gene="ftsL"
                     /locus_tag="RD508_000538"
     CDS             25850..26251
                     /gene="ftsL"
                     /locus_tag="RD508_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HDT7735162.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26252..28444
                     /locus_tag="RD508_000539"
     CDS             26252..28444
                     /locus_tag="RD508_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDT7735163.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGIAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28470..29432
                     /locus_tag="RD508_000540"
     CDS             28470..29432
                     /locus_tag="RD508_000540"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDT7735164.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29446..30807
                     /locus_tag="RD508_000541"
     CDS             29446..30807
                     /locus_tag="RD508_000541"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDT7735165.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30833..31921
                     /gene="murG"
                     /locus_tag="RD508_000542"
     CDS             30833..31921
                     /gene="murG"
                     /locus_tag="RD508_000542"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDT7735166.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31936..33156
                     /locus_tag="RD508_000543"
     CDS             31936..33156
                     /locus_tag="RD508_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HDT7735167.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33312..34637
                     /gene="ftsA"
                     /locus_tag="RD508_000544"
     CDS             33312..34637
                     /gene="ftsA"
                     /locus_tag="RD508_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HDT7735168.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34660..35901
                     /gene="ftsZ"
                     /locus_tag="RD508_000545"
     CDS             34660..35901
                     /gene="ftsZ"
                     /locus_tag="RD508_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDT7735169.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35918..36595
                     /locus_tag="RD508_000546"
     CDS             35918..36595
                     /locus_tag="RD508_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HDT7735170.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36609..37208
                     /locus_tag="RD508_000547"
     CDS             36609..37208
                     /locus_tag="RD508_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HDT7735171.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37223..37510
                     /locus_tag="RD508_000548"
     CDS             37223..37510
                     /locus_tag="RD508_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HDT7735172.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37559..38341
                     /locus_tag="RD508_000549"
     CDS             37559..38341
                     /locus_tag="RD508_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HDT7735173.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38362..39069
                     /locus_tag="RD508_000550"
     CDS             38362..39069
                     /locus_tag="RD508_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDT7735174.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39331..42129
                     /gene="ileS"
                     /locus_tag="RD508_000551"
     CDS             39331..42129
                     /gene="ileS"
                     /locus_tag="RD508_000551"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDT7735175.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42178..43704)
                     /locus_tag="RD508_000552"
     CDS             complement(42178..43704)
                     /locus_tag="RD508_000552"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HDT7735176.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43719..44366)
                     /locus_tag="RD508_000553"
     CDS             complement(43719..44366)
                     /locus_tag="RD508_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HDT7735177.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44550..44879)
                     /locus_tag="RD508_000554"
     CDS             complement(44550..44879)
                     /locus_tag="RD508_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HDT7735178.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            45056..45784
                     /gene="sfsA"
                     /locus_tag="RD508_000555"
     CDS             45056..45784
                     /gene="sfsA"
                     /locus_tag="RD508_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HDT7735179.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45800..46813
                     /locus_tag="RD508_000556"
     CDS             45800..46813
                     /locus_tag="RD508_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7735180.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46813..48090
                     /locus_tag="RD508_000557"
     CDS             46813..48090
                     /locus_tag="RD508_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDT7735181.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48153..50855
                     /locus_tag="RD508_000558"
     CDS             48153..50855
                     /locus_tag="RD508_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7735182.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            51007..51324
                     /locus_tag="RD508_000559"
     CDS             51007..51324
                     /locus_tag="RD508_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7735183.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51354..51674
                     /locus_tag="RD508_000560"
     CDS             51354..51674
                     /locus_tag="RD508_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDT7735184.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51782..53242
                     /locus_tag="RD508_000561"
     CDS             51782..53242
                     /locus_tag="RD508_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7735185.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53310..53531
                     /locus_tag="RD508_000562"
     CDS             53310..53531
                     /locus_tag="RD508_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735186.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53562..53744
                     /locus_tag="RD508_000563"
     CDS             53562..53744
                     /locus_tag="RD508_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HDT7735187.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53744..54157
                     /locus_tag="RD508_000564"
     CDS             53744..54157
                     /locus_tag="RD508_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HDT7735188.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54280..55461
                     /locus_tag="RD508_000565"
     CDS             54280..55461
                     /locus_tag="RD508_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7735189.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55532..55696)
                     /locus_tag="RD508_000566"
     CDS             complement(55532..55696)
                     /locus_tag="RD508_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735190.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            55850..55923
                     /locus_tag="RD508_000567"
     tRNA            55850..55923
                     /locus_tag="RD508_000567"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55884..55886,aa:Arg,seq:cct)
     gene            complement(55992..57131)
                     /locus_tag="RD508_000568"
     CDS             complement(55992..57131)
                     /locus_tag="RD508_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7735191.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGLEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(57430..58065)
                     /locus_tag="RD508_000569"
     CDS             complement(57430..58065)
                     /locus_tag="RD508_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735192.1"
                     /translation="MDNRNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(58178..58813)
                     /locus_tag="RD508_000570"
     CDS             complement(58178..58813)
                     /locus_tag="RD508_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HDT7735193.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQIEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(58847..59308)
                     /locus_tag="RD508_000571"
     CDS             complement(58847..59308)
                     /locus_tag="RD508_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HDT7735194.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(59438..59869)
                     /locus_tag="RD508_000572"
     CDS             complement(59438..59869)
                     /locus_tag="RD508_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDT7735195.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(59887..60207)
                     /locus_tag="RD508_000573"
     CDS             complement(59887..60207)
                     /locus_tag="RD508_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7735196.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            60506..61282
                     /locus_tag="RD508_000574"
     CDS             60506..61282
                     /locus_tag="RD508_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HDT7735197.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            61297..61500
                     /locus_tag="RD508_000575"
     CDS             61297..61500
                     /locus_tag="RD508_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7735198.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            61516..61854
                     /locus_tag="RD508_000576"
     CDS             61516..61854
                     /locus_tag="RD508_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HDT7735199.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            61841..62020
                     /locus_tag="RD508_000577"
     CDS             61841..62020
                     /locus_tag="RD508_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735200.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(62063..62533)
                     /locus_tag="RD508_000578"
     CDS             complement(62063..62533)
                     /locus_tag="RD508_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735201.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            62620..63318
                     /locus_tag="RD508_000579"
     CDS             62620..63318
                     /locus_tag="RD508_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HDT7735202.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            63496..63837
                     /locus_tag="RD508_000580"
     CDS             63496..63837
                     /locus_tag="RD508_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735203.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            63830..64501
                     /locus_tag="RD508_000581"
     CDS             63830..64501
                     /locus_tag="RD508_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HDT7735204.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            64507..65193
                     /locus_tag="RD508_000582"
     CDS             64507..65193
                     /locus_tag="RD508_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735205.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            65196..65945
                     /locus_tag="RD508_000583"
     CDS             65196..65945
                     /locus_tag="RD508_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7735206.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            65957..66226
                     /locus_tag="RD508_000584"
     CDS             65957..66226
                     /locus_tag="RD508_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735207.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            66231..66395
                     /locus_tag="RD508_000585"
     CDS             66231..66395
                     /locus_tag="RD508_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735208.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            66388..66690
                     /locus_tag="RD508_000586"
     CDS             66388..66690
                     /locus_tag="RD508_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735209.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            66687..66848
                     /locus_tag="RD508_000587"
     CDS             66687..66848
                     /locus_tag="RD508_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HDT7735210.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            66845..67150
                     /locus_tag="RD508_000588"
     CDS             66845..67150
                     /locus_tag="RD508_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735211.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            67150..67506
                     /locus_tag="RD508_000589"
     CDS             67150..67506
                     /locus_tag="RD508_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HDT7735212.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            67493..67711
                     /locus_tag="RD508_000590"
     CDS             67493..67711
                     /locus_tag="RD508_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735213.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            67708..68127
                     /locus_tag="RD508_000591"
     CDS             67708..68127
                     /locus_tag="RD508_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HDT7735214.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            68124..68681
                     /locus_tag="RD508_000592"
     CDS             68124..68681
                     /locus_tag="RD508_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HDT7735215.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            68678..68974
                     /locus_tag="RD508_000593"
     CDS             68678..68974
                     /locus_tag="RD508_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735216.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            69051..69464
                     /locus_tag="RD508_000594"
     CDS             69051..69464
                     /locus_tag="RD508_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HDT7735217.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            69773..69925
                     /locus_tag="RD508_000595"
     CDS             69773..69925
                     /locus_tag="RD508_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735218.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(69922..70197)
                     /locus_tag="RD508_000596"
     CDS             complement(69922..70197)
                     /locus_tag="RD508_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735219.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            70651..70857
                     /locus_tag="RD508_000597"
     CDS             70651..70857
                     /locus_tag="RD508_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735220.1"
                     /translation="MLGQCFGNHARFDSLPATLNAYDGYDYRKKIVKKLYGATYGNVV
                     SVLSVHHQASVTVAEVEDAAVNGE"
     gene            71053..71220
                     /locus_tag="RD508_000598"
     CDS             71053..71220
                     /locus_tag="RD508_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDT7735221.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            71246..71590
                     /locus_tag="RD508_000599"
     CDS             71246..71590
                     /locus_tag="RD508_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDT7735222.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            71595..71876
                     /locus_tag="RD508_000600"
     CDS             71595..71876
                     /locus_tag="RD508_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735223.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            71979..72293
                     /locus_tag="RD508_000601"
     CDS             71979..72293
                     /locus_tag="RD508_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HDT7735224.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            72271..73965
                     /locus_tag="RD508_000602"
     CDS             72271..73965
                     /locus_tag="RD508_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDT7735225.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            73985..75163
                     /locus_tag="RD508_000603"
     CDS             73985..75163
                     /locus_tag="RD508_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDT7735226.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            75126..75812
                     /locus_tag="RD508_000604"
     CDS             75126..75812
                     /locus_tag="RD508_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HDT7735227.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            75812..76972
                     /locus_tag="RD508_000605"
     CDS             75812..76972
                     /locus_tag="RD508_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDT7735228.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            76982..77857
                     /locus_tag="RD508_000606"
     CDS             76982..77857
                     /locus_tag="RD508_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735229.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            77854..78165
                     /locus_tag="RD508_000607"
     CDS             77854..78165
                     /locus_tag="RD508_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735230.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            78155..78508
                     /locus_tag="RD508_000608"
     CDS             78155..78508
                     /locus_tag="RD508_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDT7735231.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            78498..78899
                     /locus_tag="RD508_000609"
     CDS             78498..78899
                     /locus_tag="RD508_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735232.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            78892..79296
                     /locus_tag="RD508_000610"
     CDS             78892..79296
                     /locus_tag="RD508_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735233.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            79308..79916
                     /locus_tag="RD508_000611"
     CDS             79308..79916
                     /locus_tag="RD508_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7735234.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            79936..80298
                     /locus_tag="RD508_000612"
     CDS             79936..80298
                     /locus_tag="RD508_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735235.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            80500..83931
                     /locus_tag="RD508_000613"
     CDS             80500..83931
                     /locus_tag="RD508_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDT7735236.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDFIVAIGGLTAAFGILLPAILAVSYLFGPMML
                     IIGGIIAVIAGVIVAIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            83982..84719
                     /locus_tag="RD508_000614"
     CDS             83982..84719
                     /locus_tag="RD508_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7735237.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            84729..87020
                     /locus_tag="RD508_000615"
     CDS             84729..87020
                     /locus_tag="RD508_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7735238.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVDGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            87044..89170
                     /locus_tag="RD508_000616"
     CDS             87044..89170
                     /locus_tag="RD508_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735239.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSENPNLMPYITEPWVG
                     PLLGNGHTVKDSVKRVITHTKTRTANSGDILSLGLGIPCTAEANNRYLITTLRPSTTY
                     TLSVTMSVGSDWTGETNTIGVRLRYLNEQGGIELPINALIPANVERDKMVTHTFTGIT
                     KDNVTSITNCYVEIFSLNSEYKGTVSVSYDVKLKAHYPNLLDGPYWLGKVPLGENIAD
                     PTVVFPHKTSEYMVYGRRNTENYIADQTYTISMKATKLTVQSFAVYIAAGRVKVGDMK
                     PTEGLANTWELTFTVTKQHIDSGVTNYLEIYQYPSATKGAVQIEWLKLEKGNTRTPNI
                     SEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINS
                     QLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKL
                     YREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSI
                     GADGAIKWRRNSSYGSDYTFAITYTI"
     gene            89187..89336
                     /locus_tag="RD508_000617"
     CDS             89187..89336
                     /locus_tag="RD508_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735240.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            89333..89779
                     /locus_tag="RD508_000618"
     CDS             89333..89779
                     /locus_tag="RD508_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735241.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            89781..89918
                     /locus_tag="RD508_000619"
     CDS             89781..89918
                     /locus_tag="RD508_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HDT7735242.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            89956..90249
                     /locus_tag="RD508_000620"
     CDS             89956..90249
                     /locus_tag="RD508_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735243.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            90246..90470
                     /locus_tag="RD508_000621"
     CDS             90246..90470
                     /locus_tag="RD508_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HDT7735244.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            90467..>91035
                     /locus_tag="RD508_000622"
     CDS             90467..>91035
                     /locus_tag="RD508_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7735245.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLA"
BASE COUNT        30792 a        14825 c        19154 g        26264 t
ORIGIN      
        1 atataattat taaagggaaa catttttaca gctataattt gaaaaaaatt tatcgttatt
       61 atatgattaa gaaggattga ataaagaaag aagttgaaaa cgatacctga ttacaaaaaa
      121 ataactttta taagttctat aacgttgatt atatttttaa ttcttattct tctcgtcgtc
      181 ttggttcccc gaatttttgg tttgactcct tatattattg aggacaaaga aatgagtcca
      241 tattatgcac aaggaaatct gatatatgta cgaccgaaaa atacaaatga gattttagtc
      301 ggagatatta ttacatatta tgaaaattca ggaaaaaaaa tctcgacgcg tcgcgtaata
      361 gccgttgaaa acaaccacga agatttttat acaaaagctg atacaaagac ttatattgag
      421 cctggagtag taaaaaagag aaatattatc ggtagtccca tctttcagat tccatatatt
      481 ggactagtcc tttcaaaaac ggcatttgca tggattcagg ggttattctt tacgattgct
      541 ttttgcctaa caggaatcac agcatggaat acctttgtag agttgaaaaa gaagcggaga
      601 cgaacacaga aatttttgta agaatgttaa aaacataaat gtattccaga gatccaacga
      661 ctcttctgaa catgaaacac gagaaaacac tcatgcagct tgtagattta gtcagttgtt
      721 cgtataatgt gtgaagagga ggagtagtat gcgcaatgaa atgatgcatc gtcctgtagt
      781 caaagaagaa ctattggatt ttatgcgtac ccagcaaaaa aaattaccgg gtgagctagg
      841 caaactggaa gaagaagctc atgtagcaga agtaccagtt attccccatg aaacagttgt
      901 atttttgaaa tttttacttg gacagcttca gcctgaacga atcttggaga tcggagcagc
      961 tatcggtttt tcatcaagtg tcatggccac gacaatcgga gaaaacgctc atgttacgac
     1021 aattgatcgt ttcgatgtca tgatcgagaa agctaaaaaa aactatgaac gtctaggact
     1081 gacagataaa gtgactttgc ttgaaggtca agcagcagat atcttgccgg agttgtctgg
     1141 tccgtatgac tttattttta tggatagtgc aaaatcaaaa tatattgaat ttttacctga
     1201 atgcttacgt ttgttaagaa aaggtggcgt tttgatggta gatgacatct tccaaggagg
     1261 aacgatcttg ctcccagatg aagagattcc ccgtggcaaa cgagctatcc atcgtaaatt
     1321 aaatgaattt cttcgtgttg tgatggatca tcccgatttg acatcgacaa tcttgccatt
     1381 aggtgatggt gtgatcttaa tgacaaagga atcagaaaca atcgagttgt gatacatgat
     1441 tatggcagcc tgtagataat cgattgaatc gagggctcaa ttcgaacttg atgtaaaagt
     1501 ttctatattt gtaagtcaat taaaggatac aggaaatcta aataaacagg agtagcatga
     1561 agtcaatgta gctcctgttt tcaattgata accttagaac agctgaagga gaatgtctcg
     1621 ttttaaaaga ttgatttagt agttgggcca aaataattca ttatttgcta attaaataac
     1681 tatttcgtat tgacagaagc aatttaatta tctataatta ttgatgttcc gctgattctt
     1741 gtcatagtag ctcagctgga tagagcatcc gccttctaag cggacggtcg ggggttcgaa
     1801 tccctcctgt gacgctaaaa aaccgttaga aactgaggtt tctaacggtt tttctttgtt
     1861 ttttgtgcca atattgtttg ttttcaaagg caaataaaat aaaaaaacat ccttatcgag
     1921 tacaattata aggagcaaaa aaataaaact catcagaaaa gaggaagaag atatgacgat
     1981 actatctaga attttagtga ctctagttgc aattgaattt ttttatatca tgtatatcga
     2041 aacggtgaga actgattctg acacgacaag tagggttttt aaaatgagta aagaagagtt
     2101 aagcagaaaa tctgttcaaa cattgtttaa gaaccaagga gtgtacaatg gactattagg
     2161 agtgggacta ctttatggag cttatctttc ttccgcatct aaagaaatca caagtatgct
     2221 attaatatct attttttttg ttgcattata tggcagtttg actagcgatc gttggatttt
     2281 actcaaacaa ggtgggctag ctctgttggc attgctttct attttcttat aaatatagaa
     2341 aaaataagaa tttatctaac aggaaacttt gtgaaaaata ttactttatc tcatgaaata
     2401 tgatattcta atgaatggta ttttagaaaa tttcatgaaa aaggagttag ataggtgttc
     2461 aaaaattatg tttcctcact aaaaaaagaa ttttcaggtt atgatctttc aagatttcag
     2521 aaagatcttt tggctgggat cacagtagct gctgtagcat tgcctttagc cttggctttt
     2581 ggggtatcaa gcggagctga tgcggccgca ggtttgatta cggctatcat tgccggtatc
     2641 gttattggcg gtttatcagg cggtttttat caaatatcag gtccgacagg tgcgatggca
     2701 gctatcttga tgtctattgc ggcaacaaag ggaatgcaag gtgtattgct tgctactttt
     2761 ttagcgggtc tatttttact tgcagcagga cttttccgat taggaacact gacttctttt
     2821 atcccagcac ccgtaattac ggggtttact tcaggtattg ctatcattat tgcattaggt
     2881 cagatcgata atttatttgg tgttcactcg gaaggtacaa acgttattga aaaactaagt
     2941 agttatcaaa cgataggatt tccgataaac acagcctctt tgatcatggg agggctagtc
     3001 attttaggga tgtttatcta tccaaaaaaa tgggcgaaac gaatgcctag ttcgctgctg
     3061 gctatcattt tggcaacagc agttatgcta ttgttccatt taccagtagc aactgtgggt
     3121 aagattccac aaacattgat cagtagtaat cgtttgaata tgggagattt tagcttttct
     3181 gccttgcaac aagtggcagt tccagctatt agcattgctt tattaggaat gattgaaagc
     3241 ttgctatgtg gtgcttcggc tggccgaatg gcaaataagc ccttagatag caatcaagaa
     3301 ttaatggcgc aaggaattgg aaatctgttg cttcctttct ttggcgggat tcctgctact
     3361 gcggccatcg cccgtacaag cgtggccatc aaatctggtg cacaaactag attagctggt
     3421 atgatacatg cagttgtctt actgctctcc atgcttgttt ttgcgccagt gatgtcacag
     3481 attccaatgc cagcacttgc aggtgttttg attgtgacgg cttggcgtat gaatgaatgg
     3541 gaaacgatca aggagctatt tactaataaa tattggtcag cagttctatt gtttatcctt
     3601 acgatgattt gtacagttat ctttgattta agtattgcta tcgtgatcgg ggtgatcggc
     3661 ggctgtgtat tttttgttgt caaaagcgct gctatcacga tttcattaga aacgatcgat
     3721 tggcaaagaa tggggctgcc agaaacggaa aagctgaata actggacagt agtgtatatt
     3781 agtggtccac tgttttttat gtcttcagaa aaactcaaaa ataaattgga agaactaaat
     3841 catcacgatg gtgtcatttt ctccatgcga ggcgtaccaa gtattgattt gacggcacgt
     3901 gcagtttttg atgaatttca agaaaaagca gagcaaagag gacaaacgat tatctatact
     3961 tccttgcagc cagaagtaga aaaacaactt tctcacttgt gggaacatac attcacgcat
     4021 caacatcaaa cagttgctca tgcgttgaca gctttacatg cgaaatatac tgcaattagc
     4081 cattaaaaca atgaaaaaga acagacaaga ctgtaaactg aagattttat ggtcttgtct
     4141 gttcttttta atattgctgt aaaagtgaag ctagtacttg ccagtcttga tggataacag
     4201 gtacaaggga gcgattgtag aaaatagctg ctggatgaaa aagtggaaga attcgatagt
     4261 ttttttctga ccattcgtag gcatcctttt gttctgttaa ttgtaagaca ggccctgtat
     4321 agagttgacc atgatttttg gtaaccgtat attctttgcc aagtaaacgt tgaagaccaa
     4381 tgtttccaag tgtcgcaatt aattttggct ggaccttcat cagttcgtaa tccaatattg
     4441 gtgcatgcgc aaatacttcg gaacgagtag gtgtccgatt tggataaaca gtttctgact
     4501 gttgtgtccg tttattgatc cgatgagtca cgcgatacgg gcggctcctt acagcactgg
     4561 tgatatacac ctcttctcgt gttaagccag ttgaagaaag tgcctgcatc aattcttttc
     4621 cagcttgacc gctaaaagga acatgcgtat caatctctgt tttccctggg gcttctccca
     4681 cgagcatcag tttaggatga agaggtcctt gcccagcgat aaatccttct acaggacggc
     4741 cgttcattct taaagaagct tcttgtatca gttcttttgg gtattccatt tatgctcctc
     4801 ctttttcttt tattataaga ataaaagaaa cacaatgcga ctattttatt tggtagaact
     4861 gtgaggatag aaaagcagaa gtattgcttg aatttttgtt ttactttttg attttaaatt
     4921 tagttgacta acggttgctg ttctggtaag ctagtactgt tgtaattgtg gactccacag
     4981 ctacaaccgc tcagaacaag taataagcac agcatatgct gtcacttcgg atggcgagtc
     5041 taagtatatc agaaggaggt gctttatagc atgtacgcaa ttattaaaac tggtggtaaa
     5101 caagtaaaag ttgaagtggg acaagcaatc tatgttgaaa aacttgacgt tgaagcagga
     5161 gaaaaagttg tttttgacga agttatctta gtaggcggag aatctacaaa agtaggcgct
     5221 ccaactgttg caggtgcaac tgttgaaggt actgttgaaa aacacggcaa acaaaagaaa
     5281 gtcgttactt tcaaatacaa acctaaaaaa cattcacacc gtaaacaagg tcatcgtcaa
     5341 ccatatacaa aagtggttat cgacgcgatc aacgcttaat agcgtttgag aaagaaggcc
     5401 tatatatgat caaaggaaca tttaagcgaa atgacgcagg tcagatcgtt tcattcactt
     5461 tgaccgggca tgctgatgct ggtccttatg gaagtgatat cgtttgtgcg ggtgtttctg
     5521 cgttagcgat cagcactgtc aacgggattg cctcattagc cggttttgag ccgattgttg
     5581 aaatgaatga agaagaaggc ggttatcttt ataccgaagt cacttcagga atgacacaag
     5641 aacaaaacaa tattgctgag attctattag aaaatctttt attaggatta caatcgatag
     5701 aagctgaaaa ctcagaatat atccaaatta aaacaattaa tgataaatag gaggtgcaga
     5761 ccatgttgtt atctatgaat ctacaattat ttgcccacaa aaaaggtggc ggttctacat
     5821 ctaacggccg tgactcagaa tcaaaacgtc taggtgctaa acgtgctgat ggacaaacag
     5881 ttacaggtgg atcaattctt taccgtcaac gcggtacaaa aatctatcca ggtgtaaacg
     5941 tgggtatcgg tggagacgac actttatttg caaaagttga tggcgtagta cgtttcgaac
     6001 gtaaaggccg taacaaaaaa caagtgtctg tttatccagt agctcaagaa gcttaattga
     6061 atcttatgat taaagaggtt gtgacaagac ttttgtcaca gccttttttg tttataaaaa
     6121 taaaagttgt agtggaggct acgaagttta ctttgtcttt ttacacttaa tatttttttg
     6181 ccaatttgga atcaggatgt tttgataact atcgttttca attgatggaa gctatattgt
     6241 ttgctatcag tgaaataatt atatggtaaa cagtgttctt tttcttgttt ccattataaa
     6301 aatcgtatcg ggatttttcg ttcttttaaa ttgaacattt ctatctatcc gcgtgttatc
     6361 aacaaaacaa aatcaggtaa atagttgacg aaacagaaat aaatacatag tattatgttt
     6421 tgaagcctaa gtacaatagt ctatagaaaa ggagcgatac cattggcaaa acgcattgac
     6481 cgaatttata tgtatgtcaa agaaaaaacc gctcatttaa caaaggcaga atatgatcaa
     6541 ggagtaacaa cacaggaaat tgctgaagtg ttagggattc agcgaacaaa tagcagtaaa
     6601 gatctgaatc agctagtgcg cgaaggaaaa ctgataaaga cagacggacg accagtacgt
     6661 tacatatatc aaacactcgt tacgcacgta aagccagtta caaaacatgt agtcagttac
     6721 aaagaaacgc cggtctctga agaaaaaaat acactccaaa tagatactaa ggatatcttt
     6781 gcaaaaatca ttggagctaa cggcagcatg aaaaattcag tggaacaggc aaaagctgcg
     6841 attttgtatc cgccaagagg attaaattgt ttgattacag gacctaccgg atcaggaaag
     6901 acttattttg cacacgcgat gtatcatttt gcaaaagcgc atcatgtaat agatgaggaa
     6961 acggaactga ttgttttcaa ttgtgctgat tatgccaata accctgagct tttgatgagt
     7021 catttatttg ggtacgcaaa aggtgctttt acaggcgcag atgaagaaaa aatggggatt
     7081 atcgatcaag cggatggcgg tatgctgttt ttggatgaga ttcaccggtt gccgcctgaa
     7141 ggtcaagaaa tgatctttta ctttatggat catggaactt acagtcgtct tggggaaaca
     7201 acgaaatccc atgaagcaaa tgtacggatc gtaggtgcga ccacagaaga cccaggttct
     7261 tctctattag aaacttttgt tcggcgtatc ccaatcaata tcaaacttcc ggcttttgaa
     7321 aaacgtcctg caaatgagaa agtcgattta gtaaaaatca tgattgccca cgaagcaaac
     7381 cgcacgcagc gaaagatttc tttgacagaa gatgtagcaa aagcattgat cggcagtgtg
     7441 acctatggaa atataggaca attgaagtca aatatccagt tagtatgtgc acgaggattt
     7501 ctaaatcata tgcaatcacc cgaaatctcg atcacaatcg atgatttgac agaagggatt
     7561 cgtagcggat tgattcaatt agcaagcaac cgcagtgcaa tggcagagct ttctaaaata
     7621 ttggagccaa agataactgt agcaccaaat gatacgatca tgaaaatcca atcggactcc
     7681 tatgagttac cttataatct atatgatatc atcggagata aagcagcttt actgaagtcg
     7741 gatggtttgg atcaagaagc aatcaatcat ttcatttcta cagatatcaa catccatctg
     7801 aagtctttct ataaagacca tggtttttct tttaatgcag acagcaaatt agcagaattt
     7861 gtagatccga aaatcataga agtgaccaat cagatttatg taatggtcaa aagatcttta
     7921 ccatatgagt ttcagcaaaa ctttatttat gctatgagct tgcatatcag ttcttttttg
     7981 aaaaaaatca acttaggaga agaacggcat acgaatgata acatccgtga gatggctttt
     8041 gattttccag atgaatatgc tgttgcgaaa gaagtgcgta gttatatcga aacgtatttt
     8101 caagtggaga ttccagaaag tgaagactat tacttgaccg ttctactcgt ctcgttacgg
     8161 gcaaatcaag caagcggcag aatcggtgta gtcgttgcag ctcacggaaa cagcacagca
     8221 agcagtatgg tccaagttgt ccaacagttg ttagatgcag agaacgtacg agcagtagac
     8281 atgcctttgg atatggatcc gaaaacagca ttggaccgaa ttgaacgcaa tgtacaagaa
     8341 gtagatgaag gaagcggggt catactctta gtagatatgg ggtcccttgc gtcgtttaat
     8401 tcgcaaattc aaagagacac tggaattcca gtacgtactg ttgatatggt aacaacttct
     8461 ctagttttgg aaactgtacg aaaggtctca gtattaggga cagatctaga tatgttgcat
     8521 gaatcattga aaaattttcg aggttacgca gaaatatctt ctgtagaatc tgttcaggaa
     8581 gcaaaaccta ttcataagaa aaaagctgtt ttggctatct gcgcatctgg cgaaggtaca
     8641 gcacaaagaa tcaaagaatt gatcgaacga gcggtaaaca agcgtcaaga aacagaatta
     8701 gaagttctag ctttgtcgat tgtggaagtg aaagaagaac tgccagttat ccaaaaagaa
     8761 tatcagatca tagctactac tgggattact gatttgaata tccaagcccc atttattcct
     8821 ttagaacgtt ttattgatca aaatatcgaa gtcattttgg atcagttgct gatggaatca
     8881 gaattggagg aaactgaatt catctcccta gatgaagagt cagctaaaaa tacgtgtgtt
     8941 gagtttatct ctgataactt catctttatt aatggtagta agttaatcga tccaatgtgg
     9001 caattttcta cacaaatctc tcagacgacg ggaatcggcg atgaagaata tggattcaaa
     9061 atcaacctag tgatgcacac agcaggaatg atcgaacgta ttattcggaa tgaaccattg
     9121 actgtggaag aaaacgaatt gacaaataca acgaatgatc ctctttatag ccaattggca
     9181 gcctcagttg ttctgttgga agatcagata aaagtaaaag tgccgataga agaaatgtat
     9241 tatctgctac gtctagtcca taatcagtta gataaaaaag aatacactgt gccatgaata
     9301 cacaaaaacg atacactttt atagtgtatc gtttttgtgt attggttaag aatcctttaa
     9361 attcaattag tgtatcgtaa aaaagttggc acgctttttg cttatagtag tgtgtgctag
     9421 gaggtggttg ttcacacaga aatgataggg gtttctgtga agtagtgagg aagaaggagt
     9481 tttgcagatg gatattcgat tggcacgtat agatgatcgt ttaatccacg ggcaagtcgc
     9541 aacagtttgg tcgaagcaaa caggtgttga acgtatcatt gtgatcagcg atgtagtcgc
     9601 tcaagataaa ttgagaaagt ttctactaaa agaagctgca ccgccgggga tcacagcaaa
     9661 tgtaataacc gtgcagaaaa tgattcaaat ctatcatagt ggattattat cacgagcaaa
     9721 agtgatgctt ttattcacca atccccaaga tgttgaagcg gttgtccgct gcggtgtaca
     9781 gttgaagtcg ttgaatatcg gcggtatgag ttttactgaa ggcaaatcaa tgattaccaa
     9841 ttttgtttca gtaaatcaac aagatattga ttcctttcgt tacttgaaca gtcaagaagt
     9901 ggagttagag attcgaaaag tacctgctga caggaaaatc cttttgatgg aactactagc
     9961 gaaaatcaaa aaggtgtagc aagaatggtt gttggaaaag gtcaaataat tctgttgtaa
    10021 tggttagcaa ttattaatat ttttgaattt gttacaacaa aagtaaatag gaggtataaa
    10081 tatggtaggg attatcctag caagtcatgg acaatttgct gaaggaatct tacaatccgg
    10141 ttcaatgatc tttggcgaac aagaaaacgt caaagccgtg attttgaaac caagtgaagg
    10201 tccagatgac ttgagagcca aattggaaga agcggttgct tcttttgata atcaagacga
    10261 agtgttattc ttagttgatt tatggggcgg aacaccgttc aatcaatcaa acacattatt
    10321 cgaagagcac aaagataaat gggcaatcgt cagcggtttg aatttaccaa tgttgattga
    10381 agcctacgca tcacgctttt caatggaatc tgctcatgaa attgcagcac acatcattga
    10441 aacagcaaaa gacggtgtaa aagtaaaacc ggaagaatta gaaccggcag aagcaccgaa
    10501 agcagcagtt gaagacgcac aacctaaagg agcacttcca gaaggaactg tggtcggaga
    10561 cggaaaaatc aaatatgtat tagcacgtgt tgactcacgt ctgttacatg gacaagttgc
    10621 gacagcttgg acaaaagcag tgcaaccaaa ccgtattatc gttgtttcag atgcagtatc
    10681 aaaggatgat ctgcgtaaga gactaatcga acaagctgct cctccaggtg taaaagcaaa
    10741 tgttattcct attagcaaaa tgatcgaagt agcaaaagac cctcgttttg gaaataccaa
    10801 agcattgctt ttatttgaaa atcctgaaga cgtattgaca gctgttgaag gtggcgtaga
    10861 catcaaagaa ttaaatgttg ggtcaatggc gcattcggtc ggtaaagtcg ttgtaagtaa
    10921 agtattgtct atgggacaag aagacgttga agcgtttgag aagcttgaac aaaaaggtgt
    10981 gaaattcgat gtacgtaaag tacctaatga ttcacgcgat aacatggatg atattttgaa
    11041 aaaagcaaaa gctgaattag caaaagcgta ataaataata ttaaaattta taggaggctt
    11101 atcatgtcta ttatttcaat aattttagtc gtattagttg cctttctagc tggtatggaa
    11161 ggtattcttg atgaatttca atttcatcaa ccactagtgg catgtacatt gatcggttta
    11221 gttaccggta acctcgaagc tggtatcgta cttggcggta cgcttcagat gatcgcttta
    11281 ggttgggcaa atatcggtgc cgctgtagca ccagatgctg cattagcatc agtagcatca
    11341 gcaattattt tagttttagg tggacaaggt gttaaaggtg ttccttctgc gatcgcgatt
    11401 gccgttcctt tggctgttgc agggttgttc ttaacaatga tcgtacgtac aatcgctgtt
    11461 ccaatcgttc atttgatgga tgcggctgct gaagaaggaa acatccgtaa ggttgaaatg
    11521 tggcacatca ttgctgtatg tttacaaggg gttcgtatcg cggtcccagc agcagcgttg
    11581 ctatttatcc cagcacaaac tgtgcaatca ttccttgaat caatgccagc atggttaaca
    11641 gatggtatgg ctatcggtgg gggaatggtc gtagctgtag gttacgcttt ggtaatcaac
    11701 atgatggcta caaaagaagt atggccattc ttcgttattg gtttcgttgt agctgcaatt
    11761 tctcaattaa cattgattgc tctaggtgct ttaggtgttg cattagctct tatttacttg
    11821 aacctttcta aaatgggtgg ttcatcaaat aatggaggcg gaagcaactc tggtgaccct
    11881 ttaggcgaca ttttgaatga ctattaatct tgaaggagga aaataaaatg gcagaagaaa
    11941 aaatcaaatt atcaaaaaaa gatcgtttag ctgttgcgtg gcgctctacc ttcattcaag
    12001 gttcatggaa ctacgaacgt atgcaaaacg gtggctgggc attttctatg attccagcaa
    12061 tcaaaaaatt atacaaaaca aaagaagaac gttctgcagc attaaaacgt cacttggaat
    12121 tctttaatac acacccatac attgcttctc caattttagg ggttacattg gctctggaag
    12181 aagaacgtgc gaatggcgcg cctgttgatg atgtagcgat tcaaggggtt aaagtaggta
    12241 tgatgggtcc tttagctggt gttggtgacc cagtgttctg gtttacagta cgtccaatgc
    12301 taggtgcact aggtgcttca ttagctatgg gaggaaatat ccttggacca atcatcttct
    12361 tcttaggttg gaacattatt cgttgggcat tcatgtggta tacacaagaa tttggctaca
    12421 aagctggttc taaaattact gatgaccttt ctggcggatt gttacaagac gtaacaaaag
    12481 gtgcttcaat tttagggatg ttcgtattag ctgcccttgt acaaagatgg gtatcaatca
    12541 aattcttacc agttgtatca actgtaaaat tagataaagg tgcttacatc gaatgggata
    12601 aattgccttc aggtggtgaa ggaatcaaga gtgcatttga acaagttaat aatggcttag
    12661 ccctttctcc tgaaaaggta acaacattac aagacaactt agaccaattg attcctggtt
    12721 tagctgcatt aggattaaca ttgttatgta tgtggttgct taagaaaaag gtttctccaa
    12781 tcgttatcat ccttggttta ttcgtagtcg gtgttgttgg acacgtcatc ggacttttat
    12841 aatccataaa aatatagctc gggcgttgtc ccgagctttt tttatatagt atactgttca
    12901 taaacaaata tctggaggga gaaaatggtt caatcaatca atacaaaagt agacttggta
    12961 attgatgcta cttcgtttac gggtctgaca gattacgggc aaatcatgat aggtgataat
    13021 ggttttgagt tttaccatgc gcgagataga cgcaaatata tccaaattcc atgggaagaa
    13081 gtggattatg tactagcatc agtcatgcta aagggaaaat ggattcctcg atatgccatt
    13141 caaacgaaaa aaaatggtac atacacattt tcttccaaag aacctaaaaa agtgcttcgt
    13201 gcgatcagag aatatgtaga tgaagataga atggtacaat cattgagttt ctttgatgta
    13261 gtgaaacgtg gtattcgtag tatgtttaaa cgcaagtaaa aaataaagaa aacttctaag
    13321 aggaggtttt ctttattttt ttactttgca gaagaaaata tgaaatagca aaaccaatta
    13381 tttgtcccct ttaaatccca tatgctaaaa ttgattagca aagaaggagg ttatattatg
    13441 agttggttat ggacattgat tgttggagcc gtgatcggag caattgcagg tgcgatcacc
    13501 agtaaaggaa attcgatggg ctgtgtaacg aatatcattg ctggactagt cggttcaagt
    13561 attggacaag cgattttcgg cgaatgggga ccaaaagctg caggtatggc acttattcca
    13621 tctattttag gcgcagtgat tttggtagca gttgtctcat ttttctttgg aaaacgatca
    13681 taagttttta caaaatagta aactaaaagg agttgcagcg agactgtgac tcctttttgg
    13741 ctttatttat ttaaaataaa aagaagtttt ccggaaattt ttatttaact gtcgtgtacg
    13801 aagaaaagtt tgctataatg gaaaaaagcg tgcaaagaaa gagggagttt cattatgatg
    13861 ctacgtgtag aaaaattgcg caaaaaaatg caagaagaaa atttggattc atttttggtt
    13921 accagtccgt acaatcttcg ttacttaacg aactttacag gtacgacagg attagctgtt
    13981 attactttgg aaaaagcatt ttttattact gattttcgtt ataccgagca ggcggcagcg
    14041 caggctcaag ggtttgaaat tattaaaaat gtcggaccta tttttgatga ggtagcaaac
    14101 ttagtacgca aagaagaact gcactcatta gcttttgagg aaacaacagt ctcattttta
    14161 gaatattcgg ttttagaaga aatcatcgat gcggaattag tacctgtttc acagatgatc
    14221 gaagaactca gagaagtgaa agatgaagaa gaaatcgcta ttatcgaaaa agcatgtcat
    14281 attgcggata tggcatatga tcacatcctg aaaatgatcc aaccgggcat gactgagatt
    14341 gaagtcgcaa atcaactaga cttttatatg cgttctcttg gcgcttcagg tgtttctttt
    14401 gatacgatcg ttgctagcgg attgcgttcg gctatgccgc atggtgtagc aagcaaaaaa
    14461 atcatcgaac aaggtgactt gatcacattg gactttggtt gctattacga agggtacgtt
    14521 tccgatatga cacgtacatt cgctattggt gatcctgggg aaaaattaaa agaaatttat
    14581 caaatagtct tagatgctca attagcagtt attgatgctg caaaaccagg aatgactggt
    14641 gtccaattag atgcagttgc tagagattat atttcaaaac atggttacgg ggaagcattt
    14701 ggacattcta caggacatgg gatcggttta gagatccacg aaggaccaaa cgtttcttct
    14761 cgtgcagaaa agcaatttgt accaggaaat gtgatcactg atgaaccagg gatctactta
    14821 ccaggaatcg gtggagtacg tattgaggat gacttgttga tcacagaaga tggaaatcgt
    14881 gtgttgactc gttcaccaaa agaattgatc atcttatagt ttcatcaata gaagaagtaa
    14941 gcgtaaaaat cagtgttcac agactttgtt atagaaaatc actcgattta atgatacact
    15001 atagaagaac ttttaagctg taagagataa taaagttggg tgttttctcc aattcatagc
    15061 agtttgcagc tgatcggcgg cagttttctt accacgtgat cactatgccg catcatagag
    15121 aattcggatg tatctcgtgc ttaggcaaag ggaggaataa ataaatggca gatgaaaaaa
    15181 atttgatttt aaacgcaaac caagatttag gagagatcgt gatcgctcct gaagtcatcg
    15241 aagtaattat cgggattgca gcttctaaag tagaaggcgt atacggaatg cgcggaactt
    15301 ttgccagcaa tgtcactgaa ttattaggac gtgcagctca cggaaaaggt gtttacttag
    15361 caaacgagga agatggcttg aaagtagatc tttactgtta tctagaatat ggtgtttcag
    15421 ttcctaaagt agcaatggaa atgcaggaac gggtcagcca gcaagtcctt ttcatgacgg
    15481 atatcgattt atctgaagtc aatatccatg tagtagctgt tgttcctgaa aaattagaac
    15541 aaccaacaat cgaagaactt tttgaagacg aagaggaaga gaatgaataa agaattatca
    15601 agacacgaga ttcgggaaat ggcattgcag gctttatttc cattagactt caatgcagac
    15661 ctaacaaaag aagatgcgat tttcaacgca atcgaattag accaccgcga catgatcaac
    15721 gaagatgaat cagagtttgt tcctgtttat cttgatacgc tagttggcgg tgtctgtgca
    15781 aaaaaagatg aattggataa agtgattgaa aaacatttaa aaaacaattg gcacatcaat
    15841 cggatctcaa aaatggattt ggtgatcttg cgtatcgcga tttttgaaat gacttatgtg
    15901 acagatgtac cagcggctgt tgctttaaat gaagcaatcg agttggcaaa aacatttagt
    15961 gatgaccgtt cacgtaaatt cgtcaacggt gttttatcca atgtattgaa agaattagaa
    16021 gctggggcgt aagtcctagc ttttttctat gaatcatcat aaacctgtta taaatcggga
    16081 aaattctatg gtagaatgaa aacacaaaaa atatctggga gtggttagat ggcagaattg
    16141 attaacggaa aagaattagc tgaaaaaatg caggcagaga ttgctgaaaa aatccaaaaa
    16201 ttgaaagata atggtatcca tcccggatta gtcgttttat tggtagggga aaatccagcc
    16261 agccaaatct atgtaagaaa taaagaacgt gtagcaaaag aaatcggaat ccattcattg
    16321 gtagagcgtt atcctgagac gatttctgaa gacgaactac ttgcagaaat tgaaaaatac
    16381 aatcaagatc ctagttttca tggtatattg gtccaattac cattgccaaa gcatatagat
    16441 gaagaaaaga tcctgttagc tatccgccct gaaaaagacg tagacggttt tcatccgatg
    16501 aatttaggca gactccttgc gggtaaaccg gacaagattc cttgtactcc atacggcatc
    16561 atgaaaatgt ttgaagctta ttctatcgat ccggcgggta aacgagcagt agttatcgga
    16621 cgaagcaata tcgtcggtaa accgatggct cagctactct tgatggcaga tgcaactgtt
    16681 actgttgctc attctaaaac cgaaaatctg gctgaactgg cacaagaagc agatatttta
    16741 gtcgtagcaa taggacgtgg acattttgtc acaaaagaat tcgtaaaacc aggtgctgta
    16801 gtgatagatg tagggatgaa tcgtgatgct aacggtaagc tgatcggtga tgtgaaattt
    16861 gatgaagtgg agcctattgc aggctggatc actcctgtgc caaagggtgt agggccaatg
    16921 actatcacga tgctgatgta tcaaaccgta aaatctgccg aagcttttgg agcaggtgaa
    16981 tagatggcac aagaatattt aactgtcact acattaacga agtatttgaa aagaaaattt
    17041 gatgccgatc cttatttaga acgcgtatat ttaacaggcg aaatatcgaa tttccgttta
    17101 cgtgccaatg cccatcaata tttcagctta aaagatgacc atgcaaaaat atctgctatt
    17161 atgttcaaag gagcattcca aaaattacga ttccagccaa aagaaggaat gaaagtcctt
    17221 gtcgttgggc gtatttcatt atatgaagcg ggaggttctt atcaaatcta tgtagagcac
    17281 atggagcctg atggaatagg tgctttatat caagaattgg aagaacgaaa agaaaagctg
    17341 atgaaggaag gcctttttca agggcctaaa aaaatgctgc cacgtttccc aaagcgaatc
    17401 gcggtcctta ccagtccaag cggagcggtt atccgcgata tcatcacgac ggtgaaaaga
    17461 agatatccaa ttgtccaatt ggttttgttc ccaacagttg tacaaggaaa ccaagcagcg
    17521 gacaatgttg tcaggaatat ccagagagta gaagagatgg gcaatttcga tacaatgatc
    17581 atcggtcgtg ggggtggttc gattgaggat ttatggccgt ttaatgaaga gcgggttgct
    17641 cgggcgattt atcaagctaa tacgccggtg atttcatctg taggacatga aacagatacc
    17701 acgatcgctg atttagtagc agatgttcgg gctgccactc caacagcagc tgcagaatta
    17761 gctgttcctg ttttgtcaga agagttgatg cgcattcaag aacggcaagc tagattgcag
    17821 caggcgtttg tacgccagat ccagcgcaaa caagaacggt tcgagcgtgc tcgacgttcc
    17881 tatgtatttc ggcagcctga aagattgtat gaaggtcaga ccatcaaatt agaccagttg
    17941 aaacagcgat tatatcaagc tacacagcaa atttatcatg cgaaagaaaa acaaacgatc
    18001 gcattaagcc accaattgga acaagtggct ccgctttatc gagttaaagc agctcgccaa
    18061 gaaactgctt atctagaaaa acgcttagaa gagaaaatcc aacaatatat gaaacaacag
    18121 cagcagcgtt ttgctcaagc tgttcaatct cttgatttgt tgagtccatt gaaaatcatg
    18181 ggaagaggct acagctatac gacgttaaat gatcaagtag taaaaagtgt caccgagatt
    18241 catcaagggg atttgctgac gatccattat caagatggaa tcgttaaagg acaagtacaa
    18301 gagatagaca aaggagaata aaaatatgga aaatccaact tttgaagagt cactgcaaga
    18361 attagaaaaa attgtcatgc agttagaaca aggagacgtt ccattagaat cagctctaga
    18421 ttcgtttaaa cgaggaatgg aattaagcaa acattgccaa gatacattag ctaaagcaga
    18481 agagaccttg acgaaaatga tgacagaatc aaatgaagaa gttgattttg acggaaacga
    18541 ggaaagctga gatgagatta actgactttt cagctattca tctacctgct gtagaaaaag
    18601 aaatcttgtc ttttttagat gagcatacaa cggatagagg actctatgat gcgatgagtt
    18661 attcagtgaa agcaggcggg aaaagaatac gtcccttatt acttttaacg gccgttgctt
    18721 cctttgatga gcctattgat gttcccgtct atcaagtagc agctgcttta gaaatggtgc
    18781 atacgtattc cttgatccac gatgatttgc ctgcgatgga caatgatgat cttcgtagag
    18841 gaaaacctac caatcataaa gtattcggcg aagcattagc tatattggcc ggagatggtt
    18901 tgcttacagg agcattccag ctaatcagta tggcacactt aggtaattct cctaagcttc
    18961 tgctgcttca gcaattagct gtttgtgcgg gatcacaagg tatggttgct gggcaagctg
    19021 cagatatcga gggcgaatcg aaaaagcttt ctttagaaga attagcattt attcatgaaa
    19081 gaaagacagg gcatttgatt cgttatgcct tgctggctgg tggcatatta gcgaagcaac
    19141 ctgaagaaat cttattgcta cttcaacgat tagccgaaca tttaggttta gcttttcaga
    19201 taagagatga tctactcgat gtgattggta caacgaaaac attagggaaa acagctggta
    19261 aagatgaacg tatggaaaaa aatacttacc cgcgtttatt aggcctagaa aagacacgtg
    19321 aggcgttgga gattgagctg ttatccgcca acaagatcat agacaaatta gaagaggacg
    19381 ttttttcttt tgatggcggg ctgatgcgcc agatgatcaa gcaatttgat gtggagaaat
    19441 gagggaaaga atggaaaaag aacgcgtaga tgtattagcg gtcaaacaag gattatttga
    19501 aacaagagaa caagccaaac gttcagtgat ggctggtttg atttacaacg aaaaaaacga
    19561 gcggtttgat aaaccgggag aaaaaattcc agtgagtagt gaattaagag tcaaaggtaa
    19621 aaaacttcct tatgtttctc gagggggatt aaaattagaa aaagcactca aagcatttga
    19681 tctatctgtt gaaggaaaaa cattgttaga tattggtgca tccactggcg gatttactga
    19741 tgcagctttg caaaatggcg caaaaatgag ttatgcttta gacgttggct acaatcagct
    19801 agcttggaaa ataagacaag atcctagagt cgtcgtaatg gaaagagtga attttcgtta
    19861 tgcaaaaccc gaagacttta ccttaggaat tccagaagtt gctgttatcg atgtttcttt
    19921 tatttcacta aaactgatgc tgcctccatt acatgctatt ttaaaagaag agggagaagt
    19981 gattgcttta atcaaacccc aattcgaagc aggcagagaa gctgtaggga aaaacggaat
    20041 tgttcgtgac cctcagaccc atcaaaaagt tttagaagac attttgtcat ttgcggcaca
    20101 aggtggatat gatgtgctgg aattaagtta ttctccgatc acggggggag aaggaaatat
    20161 cgagttcttg gctcacttga ggaaagtacc cgaaagcgga acaatcaatt cagctattaa
    20221 tatggcagaa gtggtttcaa atgcacacga acagtttgac cataaataaa ttgtaactgt
    20281 gaaaatcaag tgagaagtat gcggattctt ctttattata ccaaggaaat aagctatcat
    20341 tgattaagaa gaatatgcta aggagcgaag acgtaatgag aaaaaaagat cggcatcgtt
    20401 tgattactcg attgttgagt gagcaagata tccgaaagca ggaagaattt gttgaaatcc
    20461 tgaaaagcaa aggaatatct gttactcaag ctacgatttc cagagatata aaggaactga
    20521 aactgatcaa ggtaccggct tcagatggcg gctaccgtta tagcatacca gctgaaacaa
    20581 acgaagatgt aaatactaaa ttggaaaaac tattaaaaga cgctttcgtg gcagttgacc
    20641 aaatggaaaa atttgttatt ttgaaaacat tgccgggaaa tgcttcggca gcagcaaatt
    20701 tgattgataa acgttacaag aaagaattat tttcgattat caatgatgac gataatgttt
    20761 tgatgattac acgaactgaa gaccaggcag ttttattgaa gaaagacttc ctgcattacc
    20821 tttaagttga ggagcgaatg tgatgctaca agaaatcagt attactaact ttgcgattat
    20881 tccggaattg cggctttctt ttcacgaagg aatgaccgcg ctgaccggag agactggtgc
    20941 gggtaaatcc attattatcg atgctttagg tctgttagca ggaggaagag gttcaagcga
    21001 ttatatacgt caaggagcag aaaaatgtgt gcttgaaggg ttgtttgaac taccaaaaca
    21061 agaaggattc tctgaactga tggttgaatt agggatcgaa acagatgagg acaatctgat
    21121 tgttcgacgg gatatgtcct taactggaaa aaatgtttgt cgagtgaatg gtcatattat
    21181 cacattagct aatctgagaa gaatcggcag ttatttagta gatatccaag gacaaaacga
    21241 acatcaggaa ctgctccagc ctgaatcaca tcttgcttta ttggatcgtt ttggagatgt
    21301 agctttccaa cagaagaaaa agagttatca gcaagaatat atctcttatc gtgagctgga
    21361 aaaaagggta cgaaaagtgc agcaaaatga aaaatcctat gttcagagaa tagatatgct
    21421 ccatttccag caagaagaaa tagctgctgc tgatttgcaa gtcggagaag aagagaaatt
    21481 aaaagaagaa agagaaaaac ttagcaatta tcaaaaaatt gctgatggat tagctgcagg
    21541 ttacggagca ctgacgaata atgaacaaaa cagtgtagat ggtgttggct tggccgtttc
    21601 agaactgcaa gggatcgccc atctagatgt ggagtatgaa gcaatttatg aaaatatcca
    21661 aagtgcttac tatttgctgc aagatgcaat cggcgatatg agtcgtcaga ttgatttatt
    21721 ggagttagat gagagtcgtt tagaagaagt tacgcaacgt ttagaattaa tccgacagtt
    21781 gaaacgtaaa tacggcgaat ccattgagtc aatattggct tactatgacg aaatcaccga
    21841 agagctagct tcttctgatt tttcagaagg tcaattggac aaaatgaaag aggaactaga
    21901 gcaaaaagag cttctacttc agcaacaagc cgcagatctt catgaagcgc gtaaaaaaat
    21961 cgcaaaagaa ttggaaaaat ccattctgca tgaattgaaa agtctgtata tggaaaacac
    22021 tgagtttgag gtacgtttct taaaagaaga aaatagacaa ttgaatcatg atggatttga
    22081 ccaaatcgaa ttttacatta cgaccaatcc aggagagcca ctgaagcctt tggtgaaagt
    22141 cgcttctggt ggcgaactgt ctcggatgtt gcttgctttg aaaactattt tttcttctga
    22201 gcaaggtgtg acaagtatta tttttgatga agtggataca ggtgtgagcg gaagagttgc
    22261 acaggccatc gcagataaaa tttctcaaat atcgaaatac tctcaagttt tgtgcatcac
    22321 tcatctgcct caagttgctg cagtcgccga ctatcaatat tatattgtga aagcagtgat
    22381 tgatggacgt acgcaaactt ctgtttcaga gttgaaaaca aaagaaagag aagaagaaat
    22441 tgcacgtatg ctggctggaa gtgagattac aaaactcaca ctcgaacatg caaaagaact
    22501 attgaaactc gcaaaaagga cctgagccac ctcgcagtgg ttcaggtcct tttcagcagc
    22561 tgatagctat attttatttt tacatgacac tcattacagc agtcaataca acagatccaa
    22621 tcgttaaaat cagcattgtc caaatgacaa attttgttac tttagcaaaa gtacttgttt
    22681 gttttttttc acgcattgtt ttcaacctcg tcattaatta gttgattcaa gtgtacaatc
    22741 ttttttccat ttccacaaga gggctttttt ataaaaactt cccttttttt aaataatagg
    22801 tagttacgat acaaataaat aatgttaata gaactagcca tataaaggca tcatcccttt
    22861 cagcaatagg taacttaatg ttcattccat agatactgcc gacgattgtc ggtatagtta
    22921 aaataatcgt taaagaagtt aaaattttca taatattatt cagattattc gatacgattg
    22981 ctgaaaaagt ctgattcatt tgttctacta gttttaattg aatgcgagaa gtagtcattg
    23041 cctgctctgt ttccaccaat acatcacgta aatgattttt caaagcatga ttttcttgga
    23101 aaagtttatt ttgcgctagt tctttcaatg catctaaatt agcagaagtc gcttctctga
    23161 aataaacgag gcttttttgg atatccatga tttgataaag ttgtttgttt tcagtggata
    23221 cttgaagttt ggcttccaaa gtatcgcatt gagattgaag cgtagctaaa taactgttgt
    23281 aagagagtgt gacctgccaa atgaattgaa agaagatatt gagattaggc gaaatatcac
    23341 tttttggaaa ggtctggcta aagactttct ttaaaaacag tggttcatga ttcgtaattg
    23401 tgataagctt ctttttgggc gtcaaaataa tagagagcgg gtatgtatcc acttgaaaat
    23461 aaccgctagg acttgtttta gcaaaaggat attgtaacaa taataacgct ggctttgtca
    23521 actttgattg attgaattct tctgtacggg aattttctgc atcgtccaat atggaagtga
    23581 tgtaatctga cggaatttca aattgatgtg tcagctgatg aatctcttct tgattaggac
    23641 gttctacaca ataccagatc gtttggtcag tttcctttcc ggtattacgc agtttctcat
    23701 tatctaatgt aaaatatttg atcatgattt tcctcctgtt gcctgtttct tttattataa
    23761 cggataggga attggaatac atggaatgtg tttgtaagat atagaatata actgcataaa
    23821 tttaaataaa atgaaacagt tgtgtaaagt atatacagta tacttgaagc aacgataaaa
    23881 aaggagttta cgttcatggg cacattcaca ccacttatct tgttttggta tatttacccg
    23941 gtaatcgttt tgtttggttg ccaatttctt gtaaaattat tttcgttaaa tcgtcgtttt
    24001 aaaataaaag cccctgattt ggcgattcct tttttgtggg gcggtatgca tgcattgtct
    24061 agaaatacag ggacaatttc tatcttaccg tttttcttta tttctgtttt gctaatggga
    24121 atttgtattg ctgttttcca agcatattat tatgaagaaa ttatttatcc gcgttatttc
    24181 aagatgactt ggcgtttggt ttttctgttg acaatcgtct tgtacgctgt cttgatcatt
    24241 gtgaacatac tttcttacct atgaaaaaaa tagaaaagct gtaaaaagtc ttttaaaagg
    24301 ctttttgcag cttgattttt aaaaaaatgt ttatgaataa aaaaagttgt tcccggattt
    24361 cccagaaaag gtggtagaaa gtgggggatt gtggtagact aattttagtt agtggaggaa
    24421 tggggggctt tcaatgttga tgggtgaatt ccaacataat attgatgcaa aaggacgttt
    24481 aatcgtgccc tcaaaacttc gtgaagaact tggcgaaaag tttgttctga cacgcggatt
    24541 ggatggctgt cttttcggct atccgatgag cgaatgggaa aatctggaag ctaaactgaa
    24601 cgaaatgccg ttggctaaaa aagacgcacg tacttttgtg cgattcttct attcggctgc
    24661 cactgaatgc gaacttgata aacaaggacg aatcaatata cccagcacgt taagaaatta
    24721 tgcagctttg acaaaaggtt gcgtagtcat cggtgtatct aaccgaattg aaatttggga
    24781 tgagacacga tggcaagatt tttctgcagc agcagaagag aactttgacg aaattgctga
    24841 aagtatgatt gatttcggac tataagaata ggaagaggct gactaatgac tgaaacattt
    24901 caacactata cagtcatgtt gaaagaaacg gtagatggat tgaacatcaa accggatggc
    24961 gtttatgtag actgtacact cggcggtgcc ggacatagtg aatatttatt aagccaacta
    25021 agttctaaag ggcatctgta tgcgtttgac caagatcaaa aagcaatcga tcacgccaag
    25081 ctgcgtttag cttcttatgt cgaacaaggt atggtcacat ttatcaaagc gaacttcaga
    25141 gaattagaag aacgcttgag tgagcatgta gataaggtag acggcatttt gtatgatcta
    25201 ggggtttcct ctccccagct agatgaagca gaacgtggat ttagttatca tcaagatgca
    25261 ccgttggata tgcgcatgga tcagtcagct cctttatccg cttatcacgt aattaatgaa
    25321 tattcctacc atgaattagt aaagattttc ttccgctatg gcgaggagaa attttccaaa
    25381 caaattgctc gtgaaatcga acgagtacga aaaacaaaac caatccaaac aactggtgag
    25441 cttgtcgaaa tcattaaaca agtcatccca gctcccgcaa gaagaaaagg cgggcatcct
    25501 gcaaaaagaa tttttcaagc tgtgcggatt gcagtaaatg acgaactcgg tgccgaagag
    25561 gcctctttag aacaggcaat ccggttattg aaagtcaatg gaagaatcag cgtaatcaca
    25621 ttccattcat tggaagacag aattgtcaaa agtatgttta aagaatatag tacggtacaa
    25681 gatctaccac cgggacttcc tgtcatacct gacgaattcc aaccagaact gaaagtcatt
    25741 actcgtaaac caatccttcc ttcagaggaa gagctaacag aaaacaatcg atcacgcagt
    25801 gcaaagttac gtattgcaga aaaaataaga atgaaagagg agtagaatga tggcagaatt
    25861 aaagaaaatg caagattacg aatatgattt acctgaattg gtggatcagc cggaacaaca
    25921 aatgcctgat tcttcttcga atcaagaaat cattcttcca caatcaccgg caaaacgatt
    25981 aaagcagatt tctgctttgg aaaaaattgc tgtggcaagc gtggcgattg ctattgttgc
    26041 tttatgtgtt ttaacagtta tgctgcgcac aaatatcagc ggagctgaaa aagaaatcac
    26101 gtcaatacaa acagaaatca atgataaaaa gcaagaaaaa acgagtttag aacaagaaaa
    26161 aaacgaactt tctcgtactg aacggattaa acaaatcgca gaagaaaaag gattgtctat
    26221 taatgacgac aatttaagga aagtgaagta aatgagtctt aaaaataaaa ttcggcggtt
    26281 tatggaaaag aaaaatctaa atccgatgaa caatcgcaaa aaagtaggta tcattttatt
    26341 tgctacgagt attggattgt tctttttatt tgccgtccgt ttctcgtata tcgttattgg
    26401 aggtcatgtt gctggtacct cattagctga aaaaacaaaa cagttgtacc aaggaagtga
    26461 agtagtaaaa gcaaaaagag gaacgattta tgatcgtaac ggtgtggcgc tcgcagaaga
    26521 tgcctcctct tattcaatta aagcgatact ctcaaaaaca tatacctctg gggataaaaa
    26581 actgtatgtt gaagaaaaga attttgataa aatagcagaa atcctgcata agaatctttc
    26641 tatagacaaa aaagatgcac tgaatatttt agaggacggc gcaaaaaaag agctgtatca
    26701 agttgaattt ggtagctatg ggaaaaatat ctcccaagaa accaagcaaa acatcgaagc
    26761 ggacatgaaa aaagaaggtg tcgctggtct ttattttgtc gaccatcagg ctcggatgta
    26821 tccaaatggc gtcttttctt ctcattttat tggatacgca gttccagaca aagatgagaa
    26881 tggcttagtt ggtaaactag gtttggagtc tgcttacaat gatatcttga gcggtaaaga
    26941 tggtaagatt atttatcaaa aagataattt tcaaaatcct ctgccaggta cagtggcaga
    27001 agaagaaaaa gctgtcgacg gacaagatat ctacacgact ttagacagca gactacaaag
    27061 ttatttagaa acactgatgg atcaagtaaa tgaagaatat cagccagaag aattgacagc
    27121 agtcctgatg aaagcaaaaa ccggagaaat cttggcaatg ggacaacgac ctactttcaa
    27181 tcctgaaaca atggaaggat tgactggaaa agatgctatc tggcgtaatt tcttggtaca
    27241 agatagttat gaaccaggat caaccatgaa agttttcact actgcagctg ctatcgaaga
    27301 aggagaattc aacgagaatg aaaccttcca atctggaaaa atccaagtag aagatgctac
    27361 gatcaatgac catgactttg gtgaaaaagg tgtgctgacc atgcgtcaag ctctttcatg
    27421 gtcaagtaac gtcgggatgg tcatactgga acagcgatta ggcggacgat ggtataacta
    27481 tttacaaaaa ctgggatttg gacaaagtac tcattctgga ttagatgatg aagtaaacgg
    27541 tgctttacct acattaaata ttgtcgaccg agcaatgagt gcttatggac aagcggtagg
    27601 tgtgacgaat ttccaaatga tgaaagcttt cacttctatt gcgaataacg gtacaatgat
    27661 tcaacctcga tatatcagca aagtggtgga tccccaaact ggagaagagc gaacaactca
    27721 aacagaagtt ctagggcaac ctttttcaaa agaaacaaca gaaaaagtcc gtgaatatat
    27781 gagagatgtt gtcgaaagcg aaaactacgg tattgcttat ggtgtatata gtgtacctgg
    27841 atacaatgta tcggcaaaaa ccggaacagc ccaaatcgct tctgatacag ggggatatca
    27901 aacaggagat acagcctacc tgtattcgat tgtggagatg gttccttctg aagatccaga
    27961 ctatgtcttg tatctaacaa tgaaacaccc taagacatat gatcgaatgg cattggctaa
    28021 aatcgcaaat ccattgatga aacgggcaat ggattttaaa gaaactgaag aagattcaga
    28081 tacagaaaca aaaacagaaa aagtatccgt agccgattat cgtaatcttg aagcggacgt
    28141 tgcagcagct gatgctcaaa aaagtggact gcaacctgta gtgatcggta atggtaaaaa
    28201 agtacaaaaa caatctactg ccaacggtga tcagttgatc tctggagaaa aactgatcct
    28261 atatactggt ggtgataagc tgatgcctga cgtaacagga tggtcaaaag cagatatcat
    28321 gaagctgggg aaaatcctcg gtattgaagt tagttttgat ggagatggtt attgtgtcaa
    28381 acaagaactt gctccatatg aaaaaatcac tgaagacaaa cttagtttta ctttagaaga
    28441 ataagaagag aaataggaga gaaaagagca tggaatggac acaagcattg attcccattg
    28501 tcagcagttg tgcaatgaca attgccgcaa tgccgctatt tattggttat tttcaaatga
    28561 aaaagcaagg tcaggcgatt cgtgaggagg gaccaaagtg gcacaatagc aaagccggaa
    28621 ctcctacaat gggcggctta gtgtttctga tcggctctat tttgacagga atttgggttg
    28681 gagcttggca aaaacagcta actcctactc ttttcatctt gctttttgta ttagcgttat
    28741 acggagtaat cggctttctt gatgatttta taaaaatatt caagaaaaga aacatgggac
    28801 tgaactcgaa gcagaaattg attggacaga ttctaggggg aatcatcttt tatcttgttt
    28861 accgttctga aggttatcca ggtgtattga atttcttcgg actagatcta cctttaggaa
    28921 tcatttatgg tattttcgct ctcttctggc ttgttggatt ttcaaatgca gtaaatctga
    28981 cagatggcat cgatggatta gttgctggct taggaagtat ctcttttgca gcttacggtc
    29041 taattgcttg gcatcagcat cagtatgatg tattaatcat ttgcttaagt gttttaggag
    29101 gtttactggg tttcttcgtc tacaacagaa aacctgccaa gatttttatg ggagatgtcg
    29161 gttcattagc gttgggcgga cttttagcgg caatttctat aatgctaaac caagaatgga
    29221 cattgctttt gattggtttg atctatgtta tggaaacagc aagtgtgatg cttcaagtta
    29281 cttcctttaa gcttacagga aaacgaattt ttaaaatgtc tccaattcat catcactttg
    29341 aaatgtgcgg atggtcggag tggaagattg atacagtttt ttggttgatc agcattgtga
    29401 cttcgttgat cacattatgg atcgtttggt aggagatgac gggaaatgaa aaaaatatca
    29461 acatatgaaa ataagaaagt gcttgtctta ggactcgcaa aaagcggagt aagtgcggcc
    29521 aaattattac atgaattggg cgcacttgtc accgttaatg atggaaaacc ttttgacgaa
    29581 aatccggaag cacaagagct gctttcttta gggataaaag taataacagg tagtcatcca
    29641 atcgaattgt tggatgaaga attttcattg atggtcaaaa atccagggat tccctacagt
    29701 catcctttag tagcaaaagc ccaagaaatg ggtattccgg taattacgga agttgagcta
    29761 gcttacgaag tagcggaatg cccaattatt gggattacag gaacgaacgg aaaaacaacg
    29821 acaacaacga tgacaggact actactgaat gcaggagcag atcaaggaat tgcacgttta
    29881 gcgggtaata ttgggtatcc agcaagtggt gtagcgcaag aagcaaaatc agaagataaa
    29941 attgtgatgg aattgtctag cttccaactc atgggaatca cagatttccg ccctcatata
    30001 gcggtgatta ccaatatcta tgaagcacat attgattatc atggtacaag aaaagaatat
    30061 gtcaaagcta aatggaacct tcaaaaaaac atgacagaaa aagattatct gatccttaac
    30121 tggaatcagt cagaactaca agaattagcg caaagaacaa aagcacgcgt actgcctttc
    30181 tcgacaaaag aagtgttgga agacggtgtg tatgctgacg attactcaat atactataaa
    30241 aaagaaaaaa taatggaaat atctgaactt ggcgtaccag gtaagcataa tgtagaaaat
    30301 gcactagctg ctatttctgt agcaaaattg tatggtatat caaatgaagc tatacgagaa
    30361 acgttgcatt ttttccatgg cgtaccacat cgtacgcaat atgtaggaga aatccaaggc
    30421 agaaaatttt ataatgattc aaaagcaacc aatattttag cgactaaaat ggctctaagt
    30481 ggatttgaaa cgtctaaggt cgtgttattg gctggcggat tagacagagg aaatacattt
    30541 gatgaattaa ttccttcatt aaaaggaatc aaagcaatgg tcgtatttgg ccaaacaaaa
    30601 gaaaagttga tggatgctgg aaaaaaagca ggcatcgaga caatagtaac agccgattct
    30661 gtagaacaag cagttccttt agcattagaa aacagtacag atggtgatgt agttttatta
    30721 tcaccagcga atgccagctg ggatcaatac ccaaattttg aaactagagg aaacagattc
    30781 atggaagctg tgaaccgatt aaaatagaaa aagtagaagc gagcgataaa aaatgaaaat
    30841 tttggttaca ggcggaggaa cagggggaca tatttatcca gctcttgcct ttgtcaatta
    30901 tgtaaagact caagaaccga atgctgaatt catgtatgtg ggagcaaaac gaggtctaga
    30961 aaacaaaatc gtccctgata caggaatgcc tttccatacc ttggagattc aaggatttaa
    31021 acgaaaaatt tccatgcata acatcaagac ggtccgattg tttcttaaga gtatccgtca
    31081 agcaaaaaaa atcctcagtg attttcaacc agatatcgtt atcggtactg gaggatatgt
    31141 ttccggagcg gtagtgtacg ctgcagccaa aatgggtatt ccaacagtta tccatgaaca
    31201 aaacagtgta ccaggtgtta ccaataaatt tttaagccga tatgtggatc ggatcgctct
    31261 ttcatttaaa gatgcggctt ccttttttcc tgaaaacaaa gcagttcttg taggtaatcc
    31321 tcgagcacaa gaagtagcag atactaaaaa atcagatatt ttgaaaacat ttgatttgga
    31381 tccagaaaag aaaacagtct tgatttttgg cggtagtcaa ggagcactta aaatcaatca
    31441 agcagtatca gtttttttaa gtgaatatat tccttcttct taccaagttt tgtatgcttc
    31501 aggagataga tattatgaag agatcctaaa taaaataaat cctgaaatac aaaatattag
    31561 tgtccagcct tatatcaaaa atatggcaga ggtcatggct tccagtgatc tgctggtggg
    31621 gcgtgctggt gcaacttcga tcgcagaatt cacagctctg gggttaccgg cagtgttggt
    31681 tcccagccca tatgttacga atgatcatca gactaaaaat gcaatgagtc ttgttcacgc
    31741 aggagcagca aaaatgattg cagataatga actaacaggt gaatcactaa gtcagacagt
    31801 caacgaaatc atgggtgatg aagaattgca aaagcaaatg tgccgagctt ctaaagaaca
    31861 aggaatccct gatgcttcaa aacgtcttta tgacttagta aaacaaataa tcaaaaaata
    31921 aaggcggtgg tcttagtgag taagaaaaaa gaaccaaaaa aattgtctca tccgtcttct
    31981 gatgaaaaca atttgactcc ttggcaaaag gctaaccgaa aatatctggc agaacaagag
    32041 atgaaaaacc aagagccaaa aaaagaagac ataacattag atacacccct ttcagattct
    32101 gaagaagaaa aaacggttca agaggaacag caagaagaaa gccagtccga gaaaaaaatc
    32161 gaattttttg aagagatcaa gcaaaagaaa aacggtggac catataacgg ttcttttttg
    32221 aaccggctgc ccaatttaaa aagtcaacgg cacaaagtac tatttcgtcg gttagctttg
    32281 atcatcactg tattgggtat accgctgatt tttttgatct attatgtttc tccttatagc
    32341 aaattacaag cagttgcagt atcaggcaat aagacagtca acagccaaga aatcatctct
    32401 gatacaaaat tgtcattagg agaaaatgtt tggggacagt attttcatcg atctacttat
    32461 atcgatcgcc ttaaaaaagc acagccaaga atcgaaacag caaatataca tttcaaaggg
    32521 atgaatgaat tcgatttgga tgtaacagaa tataaagaga ttgctttgat cgcaaaaaac
    32581 aatcaatact acccagtgat tgaaaatgga acagtattag atgaaaaagt agcaaatcct
    32641 acaaaaaatc tccctatctt ggaagagttc aaagactctg caaaaatcaa agaattaaca
    32701 aagcaataca atcagttatc atcagaatta caaaaagcaa tttctgaaat caagtacacg
    32761 ccaagagcaa gcaataaaaa tctgatccaa ttgaatatga atgacggcaa tcaagttatt
    32821 gtaaatatca ataatcttgc gaaccaaatg aaatattatt cgcaagtagc caaagatatg
    32881 gatgaaaaag gtgtgatcga catggaagtt ggtatcttct cgcatcctta cggtagcact
    32941 caagaaacgg aagaatcggg ccaatcggaa gaaacaactg aaagtgaaga aaatgcggat
    33001 caaacaaacg aatcaagtga agaggcagaa acgcaaaaag cacaaacacc tggatcgtct
    33061 agcacaaacg gatcatctga ttcaaatgat tcaagtgaaa caagtcaaat agaagataat
    33121 ccaagtacaa ctccgtcaag tttaaatgaa aattgataaa acaactttaa aaagtaagaa
    33181 tgtactttct aaaaaccagt aatttatggt agaattggaa gcagtgaata tatctattaa
    33241 taagtatatt ttaaaacgga cgctagttgt tcgcttgtat atggaatagt aagtaggagg
    33301 gaatcccatt catggcaaaa acaggaatgt atgtaggcct tgatattgga acgacatctg
    33361 ttaaagttgt cgtggctgaa tatatcgaca gccaaatgaa tattattgga gtaggaaacg
    33421 caaaatcaga agggattaac cgaggcatta tcgttgatat cgataaaacg gtccaagcga
    33481 tacaacgagc agtacgacaa gcagaagaaa aagcaggtat ccagatcaaa ggcgtaagtg
    33541 tcggtttgcc agcaaacatg cttgaagtag aaaattgcca gggaatgatt gcagttaacg
    33601 gagattcaaa ggaaatcacc gatgaagatg tcagaaatgt ggcttcagct gcccttgttc
    33661 gttcaatacc tcctgaacgt caaatcgtgt caatattgcc acaagatttt actgtcgatg
    33721 ggttcgaggg aatcaaagat cctcgtggaa tgatcggcgt aagattagaa atgtacggtc
    33781 tgttgtttac aggacctaaa acgatcatcc ataacatacg taaatgcgtg gaaaatgccg
    33841 gattaatcgt caacgaaatg gtgattactc ctttagcgct gactgaatca attctttctg
    33901 acggagaaaa agattttggt acgatcgtca ttgatatggg tggcggccaa acaacaacgg
    33961 ctgttatgca tgataagcaa ttgaagttta ccaatcttga ccaagaaggt ggcgaatttg
    34021 tcactaaaga tatctctatt gtattaaata cgtcatttaa caatgcagaa gcgttgaaaa
    34081 taaactacgg ggatgcatac ccagaacgga catcaccaga tgaagaattt ccagtagatg
    34141 tgattggtca gtcagaacca gtgaaagtcg atgaacgcta cttgtcagaa attatttcag
    34201 ctcgaatgga acagattttc aacaaagcaa aagatgcatt ggaccaaatc gaagcattag
    34261 agttgccagg tggcgtcgta ttgacaggcg gagctgctag tcttcctggt gttgtggact
    34321 tggcacaaga aatcttcggc gtaaatgtaa aattgtatgt tccaaatcac atggggctga
    34381 gaaacccggt atttacaaat gtaataagta tcgtggatta ttcagcaaac ttgagtgaag
    34441 tgtatcaatt ggcaaaaatt gctgttacgg gtgaaacctc agcagctcgt caaatggtag
    34501 ttgaacaaga aacaacaaac acatatgaga gctatgaagc acctgaagaa acaatctacg
    34561 atgagccgga accaaaagag tccggagaaa atgtaaaaaa taaaatcaag ggtttcttta
    34621 caaatatttt tgattaattc atcctgggag gaataagata tggaattctc aattgataat
    34681 aatatcaatg acggcgcagt aatcaaagtc atcggagtcg gtggtggcgg tggaaatgct
    34741 gtaaaccgaa tgattgaaga aaacgttaaa ggtgttgaat tcattacagc caacacagac
    34801 gtgcaagcat taaaaaattc aaaagctgaa acagttatcc aattaggccc caaatatact
    34861 cgtggtttag gtgctggttc tcagccagaa gttggacaaa aagcggcaga agaaagtgaa
    34921 caatccttac gcgaagcttt agacggtgca gatatgattt tcatcactgc aggaatgggt
    34981 ggaggaaccg gtacaggtgc tgcaccaatc gttgcaggta tcgcgaaaga attgggcgca
    35041 ttgactgttg gtgtcgtgac acgtccattc acttttgaag gaccgaaacg tggccgtttt
    35101 gctgcagaag gtatcgctcg tttgaaagaa aatgtggata cattattaat tatctcaaat
    35161 aaccgtttat tagaagttgt agataaaaag acaccgatgc ttgaagcttt ccgtgaagca
    35221 gataatgttt tacgacaagg tgtacaaggt atctctgatt tgatcacagc gccaggttac
    35281 gttaaccttg actttgctga cgtgaaaaca gtgatggaaa accaaggtac agcattgatg
    35341 gggatcggtg tggctagtgg agaagatcgc gtagtagaag caacgaaaaa agcaatctcc
    35401 tctccattgc ttgaaacatc tattgatgga gctgaacaag tacttcttaa catcacaggc
    35461 ggtttggata tgacattgtt cgaagcacaa gatgcttcag atatcgtagc aaatgcagca
    35521 actggcgatg taaatatcat tctaggtaca tctatcaatg aagaaatggg cgatgaaatc
    35581 cgtgtgacgg tcatcgcaac aggtatcgat gaatcaaaaa aggaacgcaa gtctagccga
    35641 ccagctagac aagcacaaat gcaatcacct gctcaaaaga ctgtattaga tatggatcaa
    35701 gctaaaccaa cttcttcaga agaagaaaac agttttggcg attgggatat cagacgtgaa
    35761 caaaatgttc gtcctagagt tgatgattcc aattttgaca atatcgaaaa aaaagaattt
    35821 gatacattca accgcgaaga aacaaaatct catggcgatg atgaattaaa tacgccaccg
    35881 tttttccgtc gtaaaaaata aaggagagga agagcacatg attgctgaca acttgcagaa
    35941 aatcaagcaa gaaattcagg attcgtgtgc tcttgttcat cgtgatccga aagaagttac
    36001 attagtagct gtaacaaaat ctgttgaatc cgctcaagct gaagaattgg ttagagctgg
    36061 cgttatgaat tgtgcagaaa accgagtaga taaattatta gaaaagaaac aagatttatt
    36121 tgattttcct gaaataaagt ggcatttaat tggtaattta cagcgcagaa aggtaaaatt
    36181 gattgtaaat gaaattgatt actttcatgc gttggacagt ttaagattag cagaagaaat
    36241 ccagaagcgg ttagagaaag aattatcctg ttttattgaa gtaaatgttt ctggtgagga
    36301 atcaaaacat ggaatttcac cagatgagct tttaccgttt gtggaatctt tagctgcctg
    36361 cacaaaaatc aaggttgttg ggttgatgac tatggcgcct aaagaagctt ctgatgagca
    36421 aatccataaa gtgtttggta cgctgaaaga attgcgtgat cttgttcaag caaaaggtta
    36481 tgcccatgca ccatgtagtg aattaagtat ggggatgagt caagactttc aaattgcgat
    36541 tgaagaaggt gcaacattta tccgtgtagg aacagcgcta ttcaaagacg aataaaggag
    36601 gaacaaaaat gccgctttta aacagaggag caattgctaa ttttttcgga ttagctgatg
    36661 aggaagagta cgaataccaa gattatcctg aaacaacaaa aaaggctgta cagccaacta
    36721 aaaaaaatac aacacagaat caatcaactc attctgtatc tgctgcgaat actcatgaaa
    36781 aacaaaaaac ggcgacttca cgtcctgtaa cgcatgaaag tattcagccg gctgaaaaga
    36841 aaaaagtaat tgaactacat caatcaccta caaaaactgt agcgaaagaa agaacagctt
    36901 caagaacctc tacacaacct aaagcaaatc ttgctggaaa aatcactgta atggaaccaa
    36961 gagcttattc tgaagctatg gcgattgcta aacgaatcat tgctggagaa gcaaccttag
    37021 tgaattttca tttagtagaa gaaaaacaag cgagaagaat cgttgatttt ctaacaggaa
    37081 cagtttatgc actagatgga gatatcaaac gtgttggaga tgagattttt ctttgtacac
    37141 cgactgggat ggagattgac agttcaaccg ctcaatcttt tgcagatgcg aatttgtttg
    37201 atctgtaaga ggaggaacta cgatttatac tattgcacta ttacttcatt tacttcaacg
    37261 ggcagcctat ttctatagca ttatcttgat ggtatatgca ttgctctctt ggtttccagg
    37321 cgggtatcaa tcagggctag gacgattatt agctaagatc tgcgaaccgt atatcagttt
    37381 gttcgatcgt ctgcctttga ggattggacc cttggatttc acaattttag gggcaatcct
    37441 gatcttgaac ttagccgtac aaggtttagc acagatcgtt atatggataa ctgtccattt
    37501 agtttattga ttgaagcaac aaaatcttta ttctcagaat agataggagg ggaaaatttt
    37561 ggatgcaaat gtataccagc actttcgggc agatgaacgt acatttatcg attcggtagg
    37621 cgattggatt gaacaggttc aaggacaata tgcaccctat ctgaccgaat ttcttgaccc
    37681 aagacaatcc tatattttag aaacactgat tcgacaaagc agtgatttgc gtttcatgtt
    37741 ttatggcgga tatgaacagg cagaaagaaa aagatgtttg attttccccg attattacga
    37801 acctgtagag gaagattttg aaacagcatt gtatgaaatc cattatccta gcaaatttgc
    37861 cagcctaagt catgggaaaa tccttggaac tttagtggga acggggatca aacgctctta
    37921 ctttggcgat atcatctcgg acggtgatcg ctggcaagta tttattgcaa atgaggtgga
    37981 tcattttgtt gctgcacaag taacaaagat tggaaaggtt gctgtacgct tggaaccaat
    38041 caaatacaca gaaatgatta tgccgaaaga tagctggaca caagaaagag gaacagttag
    38101 ttccatgcga ctagacagtg tgatctctga gatttataat atttccagac agcggtccaa
    38161 gcagctgatc gaagctggta aagtaaaagt gaactggaca gaaaatacaa gacctgattt
    38221 tgtacttgaa ctattagata ttatttcagt cagaggttat ggcagagtcc agatccaaga
    38281 acttgagggg aagacgaaaa aagaaaagta cagggtactg ttcggtgtat tacgtaaata
    38341 aaataaaaag gtggtttact catggcttta actccattag atatccaaaa taagacattc
    38401 ccgacaaaaa tgcggggata taatcaagac gaagtagatg atttcttaga tttagttgtt
    38461 cgtgactatg aggaattgac tcaaagaaat cgagaattag aaaaagcagt caaacattct
    38521 gaagaaaaac ttgagtactt caatgaatta aaagatgctt tgaaccaatc aatcatcgta
    38581 gctcaagata cggctgataa agtaaaaaca agtgcaagca aggaatccga agtgatcgtt
    38641 acttctgcac aaaacaaagc agatgagtta gttgcgaacg ctgaaaaacg tgcacatcaa
    38701 ttaacaactg atgcagaaga aaaagcaaga aaaatcttga cagatgcaac agaaaaagca
    38761 agacagcttg cgacagaaac tgaagatctt aagaaaaaaa cacgagtatt ccatcaacgt
    38821 atcagcttga tgcttgagtc tcaattagaa caagtgaaaa gtccggaatg ggatgaaatt
    38881 ttacaaccat tctccagcta cgtgactgac agccatgaag tgatcaaaga agttttagca
    38941 aaacagcttg acaatgaaaa tgatactgat gtaaactcag acacaggagt catagaagca
    39001 cctatgacgg catttgatac acaggctatt gatatctcga tcgtgcctgg tgaaaatgaa
    39061 aacgagtaga acagaaaagc actttgttat tcttaaagcg agccgatgag agtggaagtt
    39121 cggtaagaca ctgcatggtg aaagatcctc tacttgagac ctgcttttcc gaaattagag
    39181 taagaagcag cggctgacct cgttattggt cacagagagt ttgcactaga tagatgcaac
    39241 taaatttggg tggtaccacg gcatgttcgt cccttgcggc tgaacatgct tttttgtgtc
    39301 cggaaaacaa ataaaggagt gtatggttga atgaaaatga aagaaacctt gcaattagga
    39361 aaaacaaaat tccctatgcg tggtaatttg ccaaaccgag aaggcgagtg gcaaaaagaa
    39421 tgggaagaaa atcgaatcta ccaaaaaaga caagagttga acgaaggaaa acctagcttt
    39481 gttcttcatg atggacctcc atatgccaat ggtaatatcc atttaggaca ttcattgaat
    39541 aaaatcagta aagacattat cattcgttca aaatcaatgt ctggctatcg tgcaccatat
    39601 gttccaggat gggatacaca tggattgccg attgaacaag tattggctaa taaaggcgtg
    39661 aaacgtaaag aaatgtccat ggcagaatac ttggaaaaat gtcgtgaata tgcactttcc
    39721 caagtagata agcaacgagc agatttcaaa cgcctaggag ttgcaggaga ttgggaacat
    39781 ccttatgtta cattagatcc ttcttatgaa gctgcacaag tacgcgtatt tggtaaaatg
    39841 gctgaaaaaa gctatattta caaaggattg aaaccaattt actggtctcc gtcaagtgag
    39901 tcttctttag cggaagctga aattgaatat aaagatgtaa aatctccatc tatttttgta
    39961 gctttcaatg tcaaagacgg caaagatatt cttgatgaag atacagcttt tgtcatttgg
    40021 acgacaacac catggacatt gccagcaaac caaggtattg ctgtaaatcc aaaatttacg
    40081 tatgtattgg tggaagccga tggccgtaag tttgtcgtag cgaaagattt gctagaaaca
    40141 gtccaatcag aaatcggttg ggaaaatgta acagttctaa aagaatttgc tggacaagaa
    40201 atggaatata tgactgcaag tcatccattc tatgaacgtg aatcacttgt gattttaggc
    40261 gatcatgtta ctttagacgc tggtactgga ttagtccata ctgctccagg acatggggaa
    40321 gatgactata tcgctggtag caaatataaa ctatctgtag tgtcacctgt agactcaaaa
    40381 ggattgttta cagaagaagc acctggattt gaaggtatct tttatgacaa agcaaatcct
    40441 atgatcactg atctattaaa agaaaaagga gctttgctga agctagattt ctttactcat
    40501 agttatcctc acgattggcg gacgaaaaag cctgtgatct atcgggcaac tccacaatgg
    40561 tttgcatcta tcgataaatt ccgtcagaat attttggatg aagtagaaaa agtagagtgg
    40621 gttatcccat ggggtaaaac acgtttgtat aatatgatcc gtgaccgcgg cgattgggta
    40681 atttcccgtc agcgtgcatg gggagtacca cttccgattt tctatgctga aaatggagaa
    40741 gcaatcatca caccagaaac aatcgaacat gtggcaaaat tatttgctga acatggatca
    40801 attatctggt ttgaaaaaga agcgaaagaa cttcttcctg aaggatttac ccacccaggt
    40861 tctcctaatg gcgaatttac aaaagaaaaa gatatcatgg atgtctggtt tgattctggt
    40921 tcttctcatg aagctgtttt acgtcagcga ccagaattat cattcccagc agatatgtat
    40981 ttagaaggat cagaccaata tcgtggctgg ttcaactcaa gtatcacgac tagtgtggct
    41041 atcaatggtg tagcaccata caaatcagtt atttctcaag gatttgcttt agatggtgaa
    41101 ggccgtaaga tgagtaaatc tttaggaaac atcattgcac cagaaaaagt gatcaaacaa
    41161 tttggtgcag atatccttcg cttatgggta tctagtgtag attatgaagc agatgttcgt
    41221 gtttctatgg atatcttaag tcaagtggca gaagtatatc gtaaaatcag aaatacgatg
    41281 cgtttcttat tagcgaatac agaagatttc gatcctaaaa aagatactgt ttcgtacaat
    41341 gatttacgtt ctgtagacaa atatatgacc gttcgattga accaagtaat caaagaaatc
    41401 cgagaagaag ggtacgacaa atataacttc atgcatattt accgtacagt tatgaacttc
    41461 ttgacggttg atctatcgtc attctacctg gattttgcta aagatgtagt ttatattgaa
    41521 gcagaagatg attatcaacg tcgttgcatg caaactgttt tctatcaaac agctgtagct
    41581 ttgacaaaat tattgactcc tatcattccg catacagcag aagaaatctg gtcattcctg
    41641 aaagaagaag aggagtacgt tcagttaagc gagtttcctg gttatgaaga gtttgcaaac
    41701 caagaagaat tgatggatac ctggactgct ttcatggact tccgtgataa tgtcttaaaa
    41761 gcattggaag aagcaagaaa cagcaaattg attggtaaat ctttggaagc aaaactaact
    41821 gtttatccaa aacaacaagt tcgtgaaatg ttaaaagctt tggatgcaga tattgcacaa
    41881 ttattgatcg tttcaccaga ctactttgaa gttatggcag cagatgaaca agtgccagat
    41941 aacgctatgg tatttgatga tgttgctatt acagtggaaa aagcagacgg ggaaacttgc
    42001 gatcgctgtc gccaagttcg taaagatgta ggagtagatg aaaaacttcc tcatctatgc
    42061 ggtcgttgtg caaaaatcgt tgaagacttc tatcctgaag ctgtagctga aggattcgaa
    42121 gaaaagtaaa agggaaaagg gggtgtgaca tgttctttgt cacaccccct tttgttatca
    42181 atcgtttaat tttccacgtt cacgatacca gttatctggt tgccagatcc attcgaatcc
    42241 gtctttttca agtagttcga aagctgcttt aggtcccatt gatccagctt tgtagttggg
    42301 aaaatccggt tgtgtttggt cccaagcttt tcgaatgaca tccacgatat gccaagattg
    42361 agcgacttct tcccaatgag agaagttcgt tccatcacca ttcaacgcat ctaatagtaa
    42421 tttttcgtaa gcttctgggc tattttcaac catttctgca ctatttctaa attccaattt
    42481 gattggttcc gtttcaaatc cttgccctac ttctttccca ttcaaggata aagaaaatcc
    42541 ttcagttggc tgaatataga tcgttagaac attaggtgga agtgtcgtat cgtcacatgg
    42601 ttcatcgaca gatgttttga atacattaac aggaacttgt ttgaatacga tgttgatccg
    42661 agtccctttt tcagtcaaac gtttgcctgt acgtacatag aaaggaacac ctgaccaacg
    42721 gaagttatcg atagtgaatt tgcctgcgac gaatgtttca gtctctgatt gagcatccac
    42781 tttgtcttct tcgcgatagc ccttgaattg tacaccatcc aattcacctt gagcatattg
    42841 cccgcgaacg aagttttcta acacttcttc ttcgttataa atgcggatag ctttcaatgc
    42901 tttgatcttt tctgtacgga tttctttttc ggaaaatgct actggcggtt ccattgcaag
    42961 taatgctaca acctgtaaaa tatgattttg caccatgtct ttaagtgcgc cactatgatc
    43021 gtagtagccc ccgcgatctt ctacaccgag gttttcgcca aaagtaattt ggatattgtc
    43081 gatatagcga ttgttccatt gagcctcaaa aatattattg gcaaaacgga tagctgagat
    43141 gttttggatc atttcttttc ctaaataatg atcaatcctg aaaatatctt gttctgggaa
    43201 tacttctctg atttgctggt tcaattcaaa agcagactgg taatcagaac cgaacggttt
    43261 ttctatgatc aaacgattga agccattttt tgtcataata ttttgtgatt tcaaatgaga
    43321 aacgatcgtt ccaaaaaatt gaggtgccat agccaaataa tagacacggt taccgtttaa
    43381 ttgatagtgt ccatctaatc ggtcagacaa ttcttttaat gtctgataat gcgttgaatc
    43441 atttacatca tgggattgat agtaaaaatg gcttgcaaag gtagttgctt cttcatctga
    43501 aggattcaat gcacggattg tttctttgac aacttcacgg tagtgctcat cgctccaggg
    43561 acggcgagcg gttccgatta cagcaaaatg ctcgcctaaa tttccttttc tgtaaaggcg
    43621 gaacaaagac gggtacaatt tacgctgggc taggtcacct gtaccgccga atatcgtaaa
    43681 caatacattt ttttcattag acatgtggat acactccttt atattttatc gacaaaaatc
    43741 gtgctggccg ccttaaagct gacggggatt ttctttctat cattttggat agtgatcggt
    43801 ccttcataag ctgcgatgtc aacgatctca tattcttcgt tgatattcag gtcaatagtg
    43861 actaagtaat ccaacaattc tttttcatca agcactcgtg cgatacgcac ttttgtaccg
    43921 acaggatagg actccaatgt ttgtcggcgt tcttcatgga caacttcctc ttttttagga
    43981 atcgatcctc catgaggaca atgttcagga tgattcaaat agttttctaa atgatctgca
    44041 agatgttccg aagtcacatg ttccaatact tcagcatcat catggacttc attccagcta
    44101 tagtctaaat gttcaactaa aaaaacttcc cataagcgat gtttgcgaat cagactgcta
    44161 gctttttgca gtccgcttgc agtcaattgt acaccttgat aaggggaatg ttctacaagc
    44221 tcttctttca caagtttaga aatcatttca ctgacagatg cagctgagac atctagacta
    44281 gatacgattt gtttattgtt gactttcgtt gtatctccac ctagttctaa aatgattttc
    44341 aaataatctt ctcgatttgg tgtcatattc gatcatcctt tcatggtaaa aaaccatcat
    44401 tagtaagtgt aacaaaaaaa acgttaattg actatttttc taaataaaaa acaaaggatt
    44461 tttagacgtt tttacaacaa aaaacgaaag atgatagaga agactcattc tttcgtttat
    44521 aaaggatata tatatacatt gggagggatc tatttttcag ataacaactt atatgaagtg
    44581 tctgcagatt cgtcataaag agtttgttcg ggataagaaa agataagata aaaaccatac
    44641 tgatcacgta cgactaaacg atattcatct atttctacca cagatgtgcc aagagactga
    44701 ccgttgatca aaaacgtgta atcagatgta atctgtaatt gttgtttttg ctggctatca
    44761 ctaaagaacc atgtaccttg atactttgag agtccttctg acttttccgc ttgttttttc
    44821 tttttcaagt aaataaaact tgagagaacg gtaatgagtg aaccaagaaa atagatcatt
    44881 ttttttatca ccaaatcact cctttatgag aaaataatcg catagacata ttctttcttc
    44941 tttatttcat tgtaccgaat aaaagctaaa atttctctaa gactttcgac tggttttttt
    45001 actgtttttc tacaaattat gataggatac atagtaggaa gaaaggtgac ataatttgaa
    45061 gtatcagcaa gtggaaatag ctttttttat tgaccgcccg aatcggttta tagcacattg
    45121 tatgaaaaaa gacggagaaa taattattgc gcatgtcaaa aatacaggta gaggaaaaga
    45181 ggtcctgata ccaggcgctg aagtggctat tgtatttgct cctggaccta aacggaaaac
    45241 cgcctatgat ctgattgctg taaaaaagaa gggtgactgg tttaatatcg atagtcaatt
    45301 gcctaatcgg ctggcaattg atggtatttt agacggcacg atccttttac caggattaac
    45361 tggtccattt acggtataca agcgtgaagt aacttatctt cactccaaat ttgatattta
    45421 tttagagacg gtggtcggac aaaaagcatt tgttgaagtc aaaggtatga cacttgaaaa
    45481 taaagcgatt ggtgcttttc ctgatgcgcc cacactcaga ggattgaaac atataggaga
    45541 attaacgtat gccgcacaag atggttatgc cgcttatgtc ttgtttattg ctcagttcga
    45601 acatcttcat ctggcaacga tccatgaaga aatgcaacca gcactagctg atatggttcg
    45661 acatgcgcag caaagcggag ttcaaatcct cgcctataat tgtcaagtat cggcagatga
    45721 ggtaactgtc aagcaggcca ttccatttga tgtagatatc ccttttgaag atcctataca
    45781 atagaaagaa ggtaaaataa tgatcaactt aggtattatc ggaacaaatt ggattactca
    45841 tcaatttgtc caagcagctt taagcacaaa aaaatatgaa ttgacagcgg tatattctag
    45901 acatttggaa aaagcacagg aatttggttc tcattatgaa ggggatatcg aattcgcaac
    45961 agatttgaag acttttttca atattactca tatggacacc atttatattg cttctccgaa
    46021 tagtcttcac tttagtcaag ctaagcaagc aattttggca ggaaaaaatg tgatagttga
    46081 aaagccagct ttttcgacgc caaaagaaat ggatgaaatc atccatttgg caaatgaaca
    46141 caatgtgtat ttttttgaag cagcaagaaa tatccatgaa tcaggtttta aaaagattgc
    46201 cgattactta ccattaaaag acgagataat cggtgcaaat ttcagctata tgaaatattc
    46261 ttcgcgctat gaccaagtat tagatggaga agaaccgaat atcttctcga ctcatttctc
    46321 aggtggtgca ttgatggatt taggtgttta ccttgtatat gcagctgttg cttggtttgg
    46381 aatgccaaaa gaagtccatt atttcccaag aaagatttct actggtgtag atggtcttgg
    46441 atgggggatc ttacgttatg agaattttga tgtatcgatc cagccaggta aaatcggtga
    46501 ttcttattta ccgtcagaga tttattttga ctcaggaacg ctagtgatga atggagtcaa
    46561 tgcaattgaa caagcacaat ttcatgatcg cgcgcataaa gaaatcattg atttggcggt
    46621 aacagctgca gaaaatccaa tggcagatga agcagaggat tttgccaatg tcatggctca
    46681 tccgaaagat ccagcttggg gattgttgta tgaagagtgg atcgagctag ctagaaatgt
    46741 gaaccaagtg atttatgatt taagaaaaaa tggcggcatc aaattcgatg cagataatga
    46801 ggaagatttt taatgaacga atttgtacaa gtatttcccg aaaattggca gaaaaaatat
    46861 gaggataaag ggtttatctc accttctctt attcaacgag cagtttttca gccactaagt
    46921 aataaacaaa gtatagtagc ggtttctcct acaggttcag gtaaaacact ggcttatctt
    46981 tggcctctac tactaaacgt ggaaccaggt gaagcaagtg cgttggtcat ttttgcttct
    47041 tctcaagaac tagctattca agtagcagat gttgcacgtg aatggggaaa agacaaagag
    47101 ttgaaagtcc aatctttggt gggcggagcc aacgtcaaac gtcagattga gggtttgaag
    47161 gaaaaaccag aaatcttgat tggtacacca ggaagaatat tggaattgat gaaagcaaaa
    47221 aaaataaaag cacatcaagt gaaaacaatg gtatttgatg aagcagacca gctatttgac
    47281 gctgggaaca gccaaatcat tgatcaaatt cttcatcaag ctccaacaga gtatcagcta
    47341 gctttttttt cagcgacagc agatcgttcc cttgaaagca ttgaaaaaat cactgggaaa
    47401 acgtttgaga caattgacgt gacagcagag gacgattctc gaaaaggact gagacattac
    47461 tttttacgtg taccgatacg aaagaaagat gactacttga gacgtctcac gcatatagaa
    47521 gattttcatg gtctgatttt ctttaatcaa ctgactgaat taggcgtaat ggaagaaaaa
    47581 ttgctgtata gaggtgtacc ggtaggaagt ctggcctctg atcagaacaa gctactccga
    47641 aaagcagcgc tagaacaatt caaaaagaaa atggtcagag cacttttgac cacagatgtg
    47701 gcggctagag gtttagatat tacaggtctt ccttatgtag tgaatgcaga agttccgtta
    47761 agtgaagaag cttatttgca tcgttcggga agaactggtc gaatgggtaa tgaaggaata
    47821 gtaattacac tcgtacaaga taataatcta agagatttaa aacggctttt acgtccatca
    47881 aatataacac ttgaagagat ttttttatac ggaggtaagc tgcaaactga gcagccaacc
    47941 aaagaagatg cagctcctgc agtaaataaa aagtatgcga aaactttttc tggaaaggag
    48001 cagaacccag aatataacaa agaaaaaata agaaaaaaag ttaaaaataa atcaaaaaaa
    48061 gagagaaata aaggagcaag gcgcaaataa gcgccttttt atgctatgat tatgaaaacg
    48121 ggaacaaaat tggttgccag aggaggggtt atgtgaaaga acgtcaagaa gagatcttgc
    48181 agctattgac agaaaaccaa caaggattga cagcaagtga tgtagctgag cgcttaacta
    48241 tcgatcgaag caatgcaagc cgatatttaa gtgaactata caaggcccat catattgtaa
    48301 aaaccgctgg ccgaccagtc gtttactctt tgccaacgga aaagtcaaaa tctgatgaag
    48361 tgcatgtcga ctcttctacg caagtgactt ttgaaacact cgttggagaa aatgattctt
    48421 taaaagtcag catacagcag gcaaaagctg cgattcttta tccaccgcgg gggttgcata
    48481 cgattatttt tggagaaact ggtacaggga agtcgatgtt tgctgaatgt atgtatcatt
    48541 ttgcaatcga ttcagagatg ctttctgcag atgcgccatt tgtttctttc aattgtgcgg
    48601 attatgctca aaatccgcaa ctgctctttg gacacatctt tgggatcaaa aaaggggctt
    48661 acacaggagc agctcaagat agtcccggtc taatagccaa agcagacggc ggtatattgt
    48721 ttttagatga gatccaccgt ttaccgccgg aagggcagga aatgctgttt actttcattg
    48781 ataaaggtat ttaccgtccg cttggagaaa gtgcacaagt acatgaagca tctgttcaga
    48841 tcattggggc gacgactgaa tcttcagaaa gtttcttatc tacgttcaat cgacggattc
    48901 ctatggcaat caccttgccg aatcttgctt cacgttcact ggatgagcgt tatgaaatca
    48961 tctctctttt tatcaaacaa gaagcgaatc gtttgaatca acgtatcgat atcgaaaaag
    49021 aagcgattct tgccttcatg ctttatgatg cggaaggaaa tatcggtcaa gtgaaacgag
    49081 acttgaaact agtctgtgca aaatcttttt tacattaccg tactcatcat gagaaaaagc
    49141 taatcattcg aaaagaagaa ctttcccttc aagtacaaaa aggattactg aaaatcaagg
    49201 aaataccgga acgtctcgac cgattcatgg acagcaaaag tcagtatttg acatttgaac
    49261 caggatttgc tgatgttgtc tggtcacaag atccagaacg aaacatgcag gtctataacg
    49321 atattgagga aaaagtcact tctctttccg aaaccggtgt ggagaacatt gatctagaga
    49381 ccctcatttc aaaagatgtg gatgcttatt tccagacata tgtcaaagaa ttgactaaaa
    49441 gttcgattcc caaagatctt ttgccagatg aaatctggcg gttaaccaat caattgtatg
    49501 atgtggctga aaaacggtta gaccgtattt ataatgaaaa agctcgtttt gcttttgctt
    49561 tgcatctgca aagtacattg gatcgtgtga gagaaggtca tatgatcgtc cacccagatt
    49621 tgaataacgt acggaaaaat tttaagaggg aattccaggt agcaatcgat ctttcaacga
    49681 tcattgaaga agaagaacaa gttgagattc cttttgatga aatcggcttt attagtatgt
    49741 ttctttctat caatctagga gaaagtgagc ctgttaaaga aaacaaagta gatgttctca
    49801 tattgatgca cggcagacag actgcttcaa gcatgttgga gatggcacaa gaactattag
    49861 gaacaaaagt agggaaagct tttaatatgc cactggttat ggaagttcaa acaatgtatg
    49921 aagaagtgtt acaatatgtc aaaaactatc aagagcattt gacgaatggc ctactcttgt
    49981 taacagatat gggatcatta aacaccttca gtgatttgat ttatgaagag actggcattc
    50041 ggacgaaagc tatcacgatg acaagtacca tgattgtgat agaagcgata cggatggcaa
    50101 gtgttggaag aagcttagaa gatatttatc aaaatatcca gctttccttt gaatcgatcg
    50161 tacgtgatca gttcaaagcg gaaaagtctg aaactttaca gcgtaaaaaa gccgtaatcg
    50221 tgacatgctt tactggtgaa ggagtagctg ccaaattata tcagcgtatt atgccagtga
    50281 ttaatcaaaa taaggtagaa ctgatccaga tgcagttttt agaacgtgaa tcattcaaaa
    50341 aacacatcga tgccttattg gaagaatatg agatcaaagc aattgcggga acagttgatg
    50401 ttgattatca aaatatccca tttttttcag cctatgacgt ttttgatgat gaaaaactaa
    50461 atattttaaa gcgtatagct gatgatgaga tcccgacagc taaaattgtc gattcacttg
    50521 ctggatcatt aagcgatgtc ttttctattg atgaactgat ccgttcattg caaaagacag
    50581 ttcagcagat ccagaccgat ttgtcgatta tcgtggaacc tggagtagat actggaatcg
    50641 ttatccattt agccttcatg ttagacggat tgatcaaaca agaaagccat cggcaatttg
    50701 agaaactgtc tattttctca aaaatttatc gtttggaaat ggatatcgtt cgggcaaact
    50761 tgatggcact agaacgaaaa tatcaggtaa aaattccaga agatgatatc gcatttctta
    50821 cacaaatgtt tcttgaaaat aaaataaaaa aatgaacaca ctaatcatac tgtttacaca
    50881 ctaaacatct gtgtgcgcac tataaaaaag agctaaaaag catgaaaacg ctatttcagc
    50941 tctttttttt attggcatgc ttcttgcgtt atataaaagt gtaaaaaaat aaaaggagtg
    51001 ttaaaaatgg caaaaaaaac aatcatgtta gtttgttcag cagggatgag tacgagttta
    51061 ttggtcacaa aaatgcaaaa agcagcagaa gaaaaaggga tggaagccga tatttttgcg
    51121 gtctctgcct cagatgcaga taataattta gaatctaaga atgtcgatgt attattatta
    51181 ggtcctcaag tacgtttcat gaaagctcaa tttgaacaaa aacttgcgcc taaaggtatt
    51241 ccattagatg tcatcaatat gcaagactat ggcatgatga acggagaaaa agttcttgca
    51301 caagcagaaa atctaatgaa ataaatcaag tatgcagttg ggggtataac aacgtggaag
    51361 atcaacaaaa tctagaagcc atcatggggt taatcatgtt tggcggtaat gcaaagagcg
    51421 atgcaatgga agcgattgcg gctgctaaaa tcggtgattt tgagttagcg gataggaaaa
    51481 tcgctgatgc agaagaatca cttatacaag cgcatcatgc acaaacagac atgttgacac
    51541 aagaagcaca aggaaatcat atgcaagtga cattattgac tgttcacagt caagatcact
    51601 taatgacatc tattgcgttt actgatttag caaaagaaat catcgaactt tatcgtcgcg
    51661 tatacagcga ataaatacaa cttctttttt gaacggaaga agaaaaattt ttgaacggat
    51721 tttttatttt gttataagga gaactctctt tatataaaaa acttatagga ggaagtaaaa
    51781 aatgaacgga ctatcaagtt ggatggagaa atacatcctg ccggttgccg caaaaatcgg
    51841 agcgcaaaaa catttagttg ctttgcgtga tgcttttatc ggcacactgc ccgcaacaat
    51901 ggcgggatca gtcgctgtaa tgatcaatgc aattattcgt gatttaccgc aacagtttaa
    51961 cagtacctat gctgacagtt tagcagcaga caaaggaatc tttgccgtat tgaatgtcat
    52021 catcggaatc aatggttttg tctggaacgg tacactagca atcgccggat tgatctttgc
    52081 cttttcttgg gggtataatc ttgcccgagc ttatggagta aatgatctag ctggggggat
    52141 cgttggttta gctaccttga ttcaaggtat ttcctttggt ccagcattat cagcagcatt
    52201 agatgtgaat gttccttcaa atgtcgcaga tgcaatcaat agttctgaga ttggtgcaac
    52261 gattgcagat ggcacactgt cagttggatt atggggttgg ctaaaactag atcatttgaa
    52321 tggaaacgct tattttacag ttatgatcat gggagctatt tcagtcatta ttttttgtaa
    52381 attgatgctt gccaacatta cgatcaaaat gcctgattca gtaccaccag cagtatctaa
    52441 agcatttgca gccattttac cagcgacgat cgctttatac gtcattgcta ttatcaatta
    52501 tatcgtaggt cgtgtagctg atgggcaact gatcattgat ttggtgcaaa aatatattgc
    52561 agaaccattc ctaggattat ctcaagggtt gggagcagta ttgatcgtca cagtatttgt
    52621 tcaagtattc tggttctttg gtattcatgg atcaaatgta ttggcaccag tgctagaggg
    52681 aatctgggga caagcacaac taatcaatat tgatattttc caaaaaggtt ataacggaaa
    52741 aactggtaca ccagccgtgt tagatgcaat cgaagatgga aaagcttata tgtgggtccg
    52801 cggatcgttc gatgcttttg catggtttgg cggatcaggc ggaacgatcg tcttactgat
    52861 agctatcttg attttctcta aacgtgcaga ttatctaaca gtagctaaat tatccattgg
    52921 gcctggtatc ttcaatatca acgaaccagt gatgtttggt ctgccaatcg tattgaatgc
    52981 aatcatgttt atcccattct tgattgctcc agtagtagca acagcaattg gatggacagc
    53041 tacttatctt ggcctagtcg ctccggtatc gcagcaagtc acatgggtag taccgccgtt
    53101 cttattgtca ttcttagcaa caggagcgga ttggcgggca ccgatcgtaa cattagtatg
    53161 tatggtcgtg actttcttga tttgggcacc atttgtcatc tctgcaaaca aaatggaccc
    53221 tgccgcaggc gaacaacaat aagatgaacg tgaggagcgg gatgctttaa gtttcgttcc
    53281 tcataatgaa ttttcgagga ggaactgaaa tgattacaat tgccagtgca atgcaacaag
    53341 atgaaatcaa agaattgtta gaaggataca atgaagaagg aatgactttt acatttaaag
    53401 aaaaacaagg aatcaagctg ttctttgaaa caagtgcaga agatccggaa gttgcggcta
    53461 aaaaagcaaa ggaactaatc aaagcacagc cttggggaac agtcctttat tttcaatcaa
    53521 cagctgttta gaaaatggtt taaaaagata ggatggttga gatgataaaa aacggtttat
    53581 ttttatgtag tattggttct ttgatcgtgt tgtatagttt gaatccacat tcgcaaaggt
    53641 atgatttgta tagtatggtc acaggtcttt ttctaacagg attaggaatc tatttcttca
    53701 tgaaggggaa aaaaagagaa gaagcaaagg agaaaaataa ctaatggaaa tcacgaaaaa
    53761 attaaatatt ccagcatcgt ttttttacga taaagttatg gactctgtcc ttttcgatgt
    53821 acgtaaagcg accggcaaat cagtaactag aaaacagctg aaaaatttgg agtacgtcaa
    53881 acaattctcg caaaataacc gggctcgcat aaaaatcgaa gaagtcattg aaaaccagtc
    53941 ttataagttt cgtacatcga caacgaagaa tgaattcgtc gttcattatc aaatcaaacc
    54001 attggacgat tcgacctgtg aggttcatta cacagaaaaa atggagtctt atggcatgct
    54061 tcaaaagttg aatgatatgc ttttaggaac aatcttgatg tattttaaac ggagacgttt
    54121 caaaaaaatg ctagatatga tcgaagcaac gtattaaatc aatgaaacat ggtactattt
    54181 agttattgaa aaatgaagta agctagaagg aatttttcat aggaagatag atctttcctg
    54241 cgaatcctca ctagcttttt tgtaggaagg ggcagcaaaa tgacaaacaa agtaagagag
    54301 ctaggtgtat cttcgattga ggaaatgttt gatttagcca cttatgcatt taatggggca
    54361 gatacacctg aaaggcgaga acgttttcgt acacttgcgg agaattcttg gaattacgga
    54421 ttttttgatg aggaggatcg gctaacaagt caagtcatgg cgaccccttt tccagtgaat
    54481 ttttacggac aagagtacct aatggccggc attggctatg ttgcttctta tccagaagca
    54541 aggggacaag gcgggatcaa tcagatcatg gaaaagatcc ttgaagattg ccgtgatcgt
    54601 aaagtaagct tatcttatct ggcgccattc tcctatccct tctatcggcg ctatggctat
    54661 gaacaatcat ttgataaaat cagttatcaa ctaaacagtc gtgatgtgcc gtttatcaaa
    54721 aaaaaatctg gaaaaataaa gcgtatggat tttgaagatg caaaagctgc aatcagaaga
    54781 atttatgaac agatgccgga aaaccaacga gctggtctga agcgcgaaga ctggtggtat
    54841 acgtataaat tcaagcaaaa aggcaattac cagtttgctt tgcattttga tgataatgag
    54901 gaagcaacgg gatatatcgt ttatcagctt gcaacgtctt cctttattat tgcggagtgg
    54961 ggatttttgg atcatgatgc tttttgcagc cttgttcgct tcgtaagttc tcacaatggt
    55021 gcttttgaaa catttgaata ttcatgcggc tacggcggta atgatcaaaa ttatctatta
    55081 gaaaatccat ttgcttctgt aatgatcaca ccttatatga tggcgaggat cgtagatatt
    55141 tctttgtttt tggaaaatta tccatttaaa aagagacaag ctgcatttgc cctacaaata
    55201 gaagaagatc attatgcgaa atggaatgaa ggaatcgtgg aagtaacaat cgaaaatgga
    55261 aaaaatcatc tctcaaaagt agaacaaaca aaactcccaa tcgttcgagg aagtatccaa
    55321 catatcacgc agctattatt agggtatcgt aaagtggaag agttggtatt ccaagaaaga
    55381 atacaggtga caaaagaata tgaagaaacg ttaagctcaa tcttgccaca gcaacagcca
    55441 attcttaatg actatttttg ataaaaaacg ggtgatgaca atatttttgt caccaccctt
    55501 ttgtttttca tttggcattt gaaggaaaat gttaaagtaa atcctctttt ttcgtaaatt
    55561 tgaatttttt gttttctttt gttttagggt tttctttttt gtggtcttgg attgcttctt
    55621 tcgtaatctt ttcccgattt tttttagatg aatctaagcg ttctgcgtat actttttctt
    55681 ttggcttatc attcattgga aaggacctcc ctacattatt tcattctacc tctagtttat
    55741 catctgttaa ggactagtgg aaacgttttg cctaacttat aagctgattt ttttagcaga
    55801 taagcttgca agtaaaaaac aaacaagcta caattgattt attgaaattg ttcctgtagc
    55861 tcagtaggat agagcaatcg cctcctaagc gataggtcgc tggttcaatt ccagtcagga
    55921 acgtataaat aacccctgta tcctttgcgg tacaggggtt tgttttgtat ttgtgccaaa
    55981 aatgtgccaa actagttatc atttttatat aaactatcga acacagtatt gattttttct
    56041 ttatcctgat cttcaagctc tcgaacaata tgaagataag tagacattgt agtttctaaa
    56101 ctgctatgtc ctaaacgttt cgatacgcta agtatattta ctccttgata aagtaaaata
    56161 gatgcatgtg tatgccttag tccatgcaaa gtaaattgct tttcaagccc taattctttt
    56221 aattttttgc gcaaatattt gctgacggcg tttgatgaaa ctaatccatt ttttaagttg
    56281 aaaaaaacaa aattatgagg gtttttgatt tcaaaattct cgaataattc tttttgattg
    56341 attttaaact tttttaagag atcaatcgta tgtttatcaa tggaaatttt cctatttgaa
    56401 gtttcgtttt ttgtttttcc ccattcattt aatttataat tccatgtttt attaatagtg
    56461 atgatttgat cttcgaaatc gatatcttcc catgttaatc ctagaagttc agcaaatcgc
    56521 attccagtgg caccagcaac taacacgagc ataggagaag agtactgcgc agaaaggttt
    56581 tcttctacga gtttcattaa agatttaaat tgatcataat ctaaatattt atcttctttt
    56641 ggcttcaatg aatcttttcc tttgattact gcttttctag ttggatcaaa cggaattaat
    56701 ccttcttcta cggcatcttt caacgacgct ctaatatggt tattaaactt aataacggta
    56761 gattttacat ggtctttagc atacttattt aaaaagcgtt gatatcccac tctatctaaa
    56821 tcagaaatca ataccgctgg catatatttc tttatgttca ttaacgtatc ttcgtatttt
    56881 ctataagtga taggagatac tgttccttct ttataaagtt gcatccaatc ctcaaagtaa
    56941 tctgataata atagattttt gcgatcccct ttaaggcctt tgttcaagtt atattctaat
    57001 tcgttggcgg catcttttgc ttctcctttt gtcttaaatc ctgattttct tatcttcgtg
    57061 tattttccgt catctttttt gtatgaaatt tcgtattgcc aactatttcc acgtttgact
    57121 aatcttgcca taattgaatc agctctcttt ctctgataca ataggaacta taaagaagcc
    57181 cattgtttgg gttttattat tttttgcaca tcctttttgc ttgccggcgc aaggatgtgc
    57241 tatttgtcgt tttaatggta taattggatg tgtattagat catccaatca gaggtgttta
    57301 ttatgattaa agtgattttt aaaagaataa ctgaacttcc agagtttaga ttatttgttg
    57361 attattggta tgtctggttt tttattgttg cattgctgat aggtctagat gtcatattag
    57421 aaagaaaact taagtaagag ttgagttaat aaattgaatt cctaaatgag atattttgta
    57481 gcccatattt tgtttgccga catcacctaa tactatggag ctaatcgttt tttctaacag
    57541 accaaaatca gataatctat ttaagctacc atctattagc tcttgtgaat agccagacat
    57601 gctgatattt ccagtgaaat tttcgtttcc acgactcatt aagcatgcta acaattgaat
    57661 ctcaatcgat gttaattgat tcagtacaag aagataatac tcctcgttat cccatgaagc
    57721 gttgttaatt cgaagtaaac aattcttata aagattttta tacatatcta ttttattttg
    57781 tgcctttgat ttttctacct cgtcatttat cccttcgaat attccaatga gttggtcctt
    57841 gttctctaag ttgaaaacat cttctggaat ttgatcgcga atgttttcta atgattcgtt
    57901 taaatttttg tagaatttct cgatgcgttt gaaacgcttc tcgtttttag acccaaaata
    57961 aagtgactgc acaacgccac caatataagg aattgctcca ataccgcctt caactattaa
    58021 ttcaagatat tcttttttgg ttagtttttc atttctatta tccatagtta cctcctattt
    58081 tgtcatttcc tttacaagca ttgtgactcc tgatggcact cttttgtata ggttttatta
    58141 ttgtgcacaa tctaactctt agtggggcgt ggttcattta ttttttactt actttactat
    58201 taatcatatc ccattgagca taggattttt ctatgttcga tcctcttgaa ctaatttctc
    58261 ctgtaaaagt tactttatcg ccctttgtaa aggtatcagc attgtttaag tccttcgcaa
    58321 aaattacata tgaaacttta ggtgttgcag aaatatcatt ccaactttta tcatcgtact
    58381 ctttgtctgc tataatggct attctagtag tcattgattc gataacagtt ccttcaaaag
    58441 tatatgtttt accactaata tatttagtaa aagctgtatt ttgctcagta gctggagtaa
    58501 tagaataata actatctaag aaagcacccc agtcatgatt atttgtctct aaaaattctt
    58561 caatttgagt taggctttta ttgctgctgt tagatgtagt agtttgagta tcagatgatg
    58621 agctttcctg tttgttattg tcatttgcct cgtttgatga ggaaagcgag aaacctacgg
    58681 tagtaaaaat aatcccgata ataaggagaa tcataggtgt tttcttattt gtttttttga
    58741 taaatcttac aattaacatg attaaaccta taataaataa aacaatacca gtaaaaccaa
    58801 atataccgtc cattaataga tcctctttct cttttgatat tgaatattat aaaccaagca
    58861 attctttttt cttaaaatcg aattcttctt gattaataat cccttcatct aacaactctt
    58921 tatacttttt aatttcatct gcacttgaaa tttgtgtttc tttggaatta ttatctaata
    58981 tagattgttg cttctctata tattttttta aattttccat ttcattccaa tatttttttg
    59041 taaacataac ggtgttttca tctttcgtgg ccgctaatat acctccgcga ctttcgtttc
    59101 cgcctagcaa ggtaaattgt atataaccat tactcatacc tggttttttt aattgtacgg
    59161 ctgatatatt tttaaagggg atagtttttt ctcctttaat accttgatta actaaattta
    59221 taaatccttt tctaataatt gaaatagaat catcagttac tttaatcaag gtttttcctg
    59281 gagattttat taaaatctct ttttccattt tttcttcctc atttctgtga tatgattttt
    59341 tttgtagaag ctcatatatg aggaaagagc ccgtgttgca gcacgggctt ttttaatgtt
    59401 ttgctgaaat cggttttttt aataattctt gatgtattca tacatattgc cttgcgtaag
    59461 aatatttttt cttaaaatag cattggcaga cagcataaca agtgtatctg agcttattct
    59521 gaatagaata atactccata aatttttcga gattaaactg agattcatca gtcagttcgt
    59581 tctcaatata gatatttaat aaaattagaa tagctatttt atctgcttct gtttcaaatt
    59641 ttgagtgaaa agttgtagaa gtatcgtaca aaactgaaaa ttcaaaatga gaggcgctga
    59701 aatgtgcaag ttcatgagat aaatgaaagg cttctgcagt ttcaccgtat agattttcat
    59761 tcaaaaaaat gattctgggt tttggatagt agaaaccagg ctctttcatc tccatataaa
    59821 ctactttcaa attgtattcg ctcaacattt ctttcaattt caaatacata caaaccatca
    59881 ctccaactat tcattttcct ctaaagcttt agcaattgca atcgctttac gcattgtctc
    59941 cttagatatt tcttttccat caaaagaaaa aacagtatcg tcttctgata aatccacatg
    60001 tttaggggtt tctctttctt ctctacctag aaggtagtct acagagacat cgaaatagtc
    60061 agcaatccga cttaattcat ctgaattagg agtattattt ttccactttg ctagataacc
    60121 gttagaatat ccaaaattaa tttctaactg ccgtatagat atctttttcc tcttcgccaa
    60181 gtcttttatt atttcatagg tattcatcga taaaacaacc tttctaaatg tttacaaaaa
    60241 aagtttagaa aaatacgcag aaataatttg actaattctg agtaatgagc tatactatat
    60301 cttgtaaaca gatttaacaa ctaaaaagac aacaaaaaac actattgata tgtaaatgca
    60361 gaccgccaag aaagctttaa aatcaatgtt tttatgtctt atttaattat gctcttagta
    60421 tagagtatta ctcagatact gtcaattgaa tttagaaaaa agttgttaaa tttgtttacg
    60481 aatataaaag aaaggaatga gaaatatgaa cacaccgcaa atttttaatt tcgaacaaaa
    60541 cgaagttcgg acaattttag taaatgatga accatatttt gtaggcaaag acgttgcgag
    60601 tgttttgggt tattcaaaca ctaaagatgc tttgtcgcgg catgtagatt tggaagataa
    60661 gatggggtcg cgaatcacga cctcaggtca atcaagagag atgacaatca tcaacgaatc
    60721 tggtttgtac agtttaatct taaaatcaaa acttccctct gccaaaaaat ttaaacgttg
    60781 ggtaacaagt gaagtgttgc cagcaattag aaaacatgga ggttatctaa ctccagaaaa
    60841 agtagaagaa gctttgctta atccagatac aatcattcaa ttagcaactc aactaaaaga
    60901 agaaagaact ggaagattaa tcgcagaaca aaagattgca gagtacgaac ctaaaatctc
    60961 ctatttagat agcatattat cttctacaga ttcagtaaca attagtcaga ttgcagcaga
    61021 ttatgggatg tctccacaac agatgaataa attacttcat aaactaggta ttcagaaaaa
    61081 agtcggtaac caatggttat tgtgcaaaaa acacatgaac caaggataca caaaatctca
    61141 tacaactgag atcccgaaag ccgatggtgg cactaaaatt gtaatgaata ccaaatggac
    61201 acagaaaggg cgtctattta tctacgaatt actaaaaaaa gaaggatatt accctcaaat
    61261 ggatttagag gaaattggtt agaaaggagt tttagtatga ctgacattgc agaaatcact
    61321 caacgagata gagaaaaaat caaagaatat gtcgaaagtt caaagttctt aacttacacc
    61381 atgcttgctg aaagatttgg aattagcaaa agctacttat ctttaatttt aaacggtaaa
    61441 aagacttctg cagaagcaaa cagaattata gattcgatta tcactatgta cgaattgtaa
    61501 agggaggaac agctaatgca atatctagaa gcaaaaatcc caattccaga aggctatgta
    61561 attatctccc aagtggatta tgaggagtta aaaaaagctg atgatactgg tagatggatg
    61621 acgttgccag aagtgctaga acggattaac agaaaatatg attggtttac ttctagagtt
    61681 ttaaagaacc caagatatag aaatattatc gatatcgaga aaaacaaaaa tggatttgtc
    61741 tattatccag ttgaaggaag agacacatat ctatttttaa gaagtaaaac acttgaattt
    61801 ttagaaacaa atttttcgga aatcttaagg aggcaagcgg atgggaaaat ttaatagagc
    61861 gctagtgttc agcgcaccgc taatcatcta cgctttagga ctttggggaa gcaggcaagc
    61921 gttgatagga acgattgttt acatggtttg gatttttatg gggcttgatg aagctgaagc
    61981 tgagtacaga gcgaaaaagc caaccgaggg ggctgactaa aaatgaatag aaaagagaaa
    62041 ctagaatgta tattactatt actcagttta attctttcac taatttctct attgggaagt
    62101 ttgtattttt gatatcaaca attttgtgga tttgggttct atttagagta aatatcattt
    62161 ttgtttggtg attaaggagt ttattaaaat taattttccc tacttcaaat gcaaggtaac
    62221 aagatatagc acttttagga ggaatattta gcggtacagc ttcagagtat attctattat
    62281 catcgactga tcctccttta gcaattaatt tcttaaatgg agtagctgac catctgcggt
    62341 ttaagttagc ggatgaaagt tctaaattaa ctaacatagc tggttctgtt gaatagttag
    62401 aaatgattac ttttgtataa atcatatctg cagcgaagta agaagcatta agttcaactt
    62461 ctagttgagg gcgcattcct tttattttta tccctgttaa aaacgtactc aatataaaac
    62521 ttattattga catccattga aaaattgtta agtgaaaaaa attcaaaata aacaccacca
    62581 gtttttaact aaattatacc aaaaaggaga gaagaaataa tgcaagaatt agtaattttg
    62641 aaaaataaag aagctgtgac tacgagctta caagtggcag aaagcttcga gaaaaaacat
    62701 caacatgttt taagagatat tgatgcacta aaaaaagatg tgtccaattt tggacagatg
    62761 tttgtagaag gtaatgaacc agattcatat ggcagaaatc gacgagtttt cttcattagt
    62821 agagatggat ttttcttgct ggctatgggg tttacaggaa agaaagctat ctacttcaaa
    62881 caaaaataca ttgaagcatt caacgaaatg gaagatgtta ttcgcaagaa tactgttcct
    62941 caaacaattg aagatatgat gatctatcaa ttagaagaaa tgaaagatgt taaaaaagat
    63001 gtttccatgc ttaaagatac tatgcgaatt agcggacaac aagagtttga aattaagcaa
    63061 aaaggaaata tgaaagttat gggagttcta gggggaaaag aaagccgagc ttatgaagaa
    63121 atcagcaaaa aagtattctc aaaattttgg tctgaattta aacgtacctt ttcaatccca
    63181 agatatggcg agttacctcg taagagattc gatgatgctg tttcatttat tgaaatgtgg
    63241 ttgccagaaa ctgcgatccg tatggaaatt gatcaactga acagacaaca gagacttttt
    63301 ggtgatgaca atgaatagag ctgaagcgct aagaataggg acggcaattg ctaattgctg
    63361 gtggaaatac tataaaccaa tcatcctaag ccaacaacat attgacaagc aaaaagcatg
    63421 gcaacaaata aaaaagtgac tccgccggca agcaaagagt cacaaagaaa acacatcata
    63481 aggagatttt agcatatgga aaaagaactt tccactctag atcaatattt gattgatcct
    63541 gattggggca agccgaaaat tgaggaaaca agtggtcgaa aaatcagacg aaatcttttg
    63601 acgaatgaag aactagcttg ggatcaagat gatttaggca accatgtaac tatttgggat
    63661 catgtttatc ttatccatct atcgaagcat tcgaataaac ctgaatatat ttacgtcatc
    63721 gaagatggct tgattgatgc gctagaagag tacgacagag ataacttgat tgatatctct
    63781 tattacggac caggtaagaa atacattgct gaaatggagg cagaatttga tgagtgaaat
    63841 caaagggaca acgaactttg aaaaactttt tagtcgtaag ttaaataaaa ttctcaagaa
    63901 aaaaggaaat tttgattatt tatcttgggc tcacgcgtgg gagattatga aaaagaatga
    63961 tccacaggca acggtaacta ttaatgagta caaacactac agggttgttt ctggaactca
    64021 tcaagacttt cttgttgagg aatataaacc ttttcttatg gatgaaactg ggacttatgt
    64081 atctgtctca gtaacggtta aaggacacac ggaaaccgaa ttatttcctg ttttagatta
    64141 tcgaaaccaa ccagttgtta aaccaaatgc aatgcaaatc aataactcat tgaagcgatg
    64201 ctttgtgaaa gcattggctc tacacggact gggattatat gtatttcaag gggaagatat
    64261 tccaacacca cctagaatcg atacaaagaa attaaacatg ctagagacga ttctagaagc
    64321 tttcaatgag cagatgggta aagatatgac caaaacctta atcgaatatg ttaatgagca
    64381 gacagataaa ttagggctct tagctgataa cgttgaaact attgaacagt taagctatga
    64441 gcaatgtgcc ttgatggagc gagcaatagc agctaagaga aaagaattag ataagaagtg
    64501 atatgagtgt ttaaaccatt aatcgattca tattcagcgg ttctgaaaaa gttcaaagga
    64561 aaagacataa gcgcaaccat caatgaggaa gtgaacattg atcgactaaa gacgatgtat
    64621 gacggctacg atggtgatcg agtcattgaa attcgtttta ttgatcctag acgtttcacc
    64681 gtacagcaac gaaacttcat ctatgcgctg ataggcgata tttttatcga tacaggcatg
    64741 ccaacggact tctggaagga attcttctac tttcgttttg aaggtgtcac agggcgcaaa
    64801 ataagcctga aagacgaatc gaatacaact gtgagtgatg ccaatgtctt agcaaatatc
    64861 atcttagatt tcatctttga acatcatatt cctttcaaag aaggctatga gattttacct
    64921 gcgaatcaag aatattactt ctacaaatgc atcacaaaaa gagtctgctg catctgtggc
    64981 aaaacaggag ctgacatcga tcactttgac aaagcgctag gaagacgaaa gcgcaaagaa
    65041 gttgatcatg cagagtacac atttgcagca ctctgcagaa tccatcacac agagaagcac
    65101 aaaataggtg tgattaattt caaaaataaa tatcaaatca aagggatcaa attaaaccag
    65161 aaaacaatca aaaagttaaa tattggaggg taaaaatgac agaacatcga agttattatg
    65221 cgattatacc agccaacgta aggtacgaca aaagacttaa accaaatact aagttgttat
    65281 acggagagat aacggccttg tgtaatgaaa gaggcttttg ttgggcaggc aatgagtact
    65341 ttgcagattt atatggtgtg aataaagaga ccatatcgcg atgggtaagt gatttgatta
    65401 agtttggata cttgaatcgg gaaatcattt acaaagaggg taccaatcaa ataatcaata
    65461 ggtacctacg aattaatcaa taccctattg acgaaaaacg caatacccct attgacgaaa
    65521 aagtcaaaga taataataca tctattaata atacatttaa taatacaaaa gaatatataa
    65581 gagagttacc gccttcgaaa aaatcgaagg ctaagcccgt ccgtcataaa tacggagagt
    65641 ataaaaatgt tcttttgtca gatgagcaga tggagaaact caaaacagaa ttccctaatg
    65701 attaccaaga gcgaatcgaa cgactgtcag agtattgtga atcatctggt aagacttata
    65761 aaaactattt ggcaactatt cgaagttggg caaggaaaga aaaaagtgaa cctaagaacg
    65821 caagcagtgg atacaagcgc acaggaagac gagagaagct tcctgaatgg gcaatcgacc
    65881 aagaagccta tctcaagaaa aaagcgctag aacgagctaa tagacaatca aaagcaccat
    65941 tctaagaggt ggaaaaatga agatcgatta tctagaacta attaatgaaa tagcgaatta
    66001 taaaaagggc gaggaattag acgtcctgag agacgtatat gatcaactcg aagaagctgg
    66061 aattgaagga attaagaatg atcgttcgag ttggagtaag ctcagatact atttcgcact
    66121 ttatatcgat acaacacaat taagaaattt agcatatacc aaattactat ttgttgattg
    66181 tgttaaaggc ttgcaaaaac atcttaatga acttgagcag gtgtaatcag atggacctaa
    66241 agacatttac agcacagatt gaactaatgc atcaagaagc tttaagacaa agtgtatcgt
    66301 acgaagacaa gtggctcaac acgttccatg gcggacgtga gagcgcactt gatcaagtac
    66361 tcaaattact gaaaggagaa tgtcgggatg gataagaaag cggcaatgca gcgaattatc
    66421 gaattgactt attcagaaga ttggcaaaat gacaaagaag ctgcttcaga agtgatgagg
    66481 cttggaagag cgatgtgggc agacaagagc aacaagccaa gaccacgaaa aatcgcaatt
    66541 tggcacggtg acaaacttct agtgataggg acagctgaac agttagcaag tctcacaggc
    66601 ttgcacgaga aaatcgtgag gaaaagagca aggtgtggct acacagacgc taagaagaga
    66661 acgtttagat acgtggagga atcatcatga caacagaaga agtgattcaa atgcgtattc
    66721 gaagccttca gcgtgagatt gacgatctgg aacgaacaaa ggcagtgatg gtcaatgaaa
    66781 cggcgagaaa ggcaatcgat ttgcacatag agaatttaag aagggaaatc catcgattgg
    66841 aggaatgagc gtggataaga aagcagcaat gaaaagaatt gctgaattaa ccaagtcaga
    66901 atcttggcaa gaagacaaag aaatagttgc agaagtccaa aagctcggta aatcaatgtg
    66961 gactgaaaag cccaaacgga gaacgccgag aaaaattgca atctggcatg atgaccgaat
    67021 tttagtaaca ggtactgctg aacagttatc tgaaattact ggattaagca aaaacattat
    67081 ctgggataga gctaggagct tatggattga ttcaaaagga cgacagttta ggtatgtgga
    67141 ggagagataa tggatctcat tacacaatac agtgacatca tcctcaagaa aatcatgatg
    67201 aagattcaga aagataaaaa atcaaaagaa cgagctgaat tagttaagtt agaaatggct
    67261 gaaacaggag caggagtgcg aagtagcagg cattggaaag cagcagcaaa cattgaattt
    67321 tattacaacg aaattcaaaa agggttcgat cagatgcgtg agctggatcg gcaaacaaat
    67381 tggagcaaga aacttcatca agatcgtttc aaatttgtag agaagtataa agaaatatta
    67441 gaagagtatt tgaggaggac agcaaatgat aaaaaaactc gttcaattca gcatggattt
    67501 atatgatatc gaatcaggag caacactatc tgtggaatcg gaccatctaa tcataaattt
    67561 tggtggaaag cgccagatta ttttgtgggt agttgatgat gtactgtttc cagaaattgt
    67621 tcatgatttc gaagaatcaa aagcggttga gtttgaaata gtgaaaaaag taatggaatt
    67681 gattgaaaaa tacgaggagg acagcgaatg ataccgaagt ttagagcgtg ggataaacga
    67741 aagaacgtaa tgagagatgt agccgtcttg cattttacta aaaacggcaa aacaaacttt
    67801 attgaatatt ggataaatcc taccgaattg aaatcatatc acgtgcgaaa catcgacctc
    67861 atgcaatcca caggaatgaa agataagaat ggtgtggata tatttgaagg ggatatagta
    67921 ttagtcagcg tgcgaaatgg cttcgattac ttagataata aagtctgtat tgtcaaaaat
    67981 tcaatagatt attccggatt agtttgtgcc actgttgatg aagacttaga gtatcaaatt
    68041 tttaacacag agctgtttga agaatacacg tacgaagtca ccggaaatat atacgagaat
    68101 agcgagttat tggaggaaca gcgatgaata aacaggaagc aatcaaaaag ttagaaagta
    68161 ttaaagcgat aggaaatgat gcaatagctg cttgctataa cgagagtata aattcaggta
    68221 ttacgttaat gaaaaaaata gacgaaccgc agaaaccagt tattccacaa ctcgtggccg
    68281 gttggcttga gaaatctacg gaccctttta caaaagctga aaaaatagcg tatttaatca
    68341 aatctaaaga tggtgattca tattatttct gtgattggtt tgtacgagat ggcatagtga
    68401 cgcaagagca aggagaagaa ttactcgctt gggcaacaag acaatcatat gaaacactat
    68461 tgagcctata caacggctac gaggttgaga aagagccgtt atgggcaata aagaatgccg
    68521 atggaaacta tcttactaaa tgtgctttat ggggaaaaga tggagtaaat tatagttttg
    68581 aatgcaatcc atctcatcga ttgcttttca ctgataaagc aacagcggat gctgcagcat
    68641 tgttggtgaa tggaacagtg gaagaggtgg tagaaagatg aaactaaaag acggatttta
    68701 cgctagcagt cacggtatcg gcggtttaat gctagatatg ccgacaaaga accctaaaac
    68761 acgcaagaaa tcaaaattca aagtcggtga catggtccgc tgtgaagcag aagagttcgt
    68821 ttatccgttc agaggatacg ttaaaaagat actgtcaaac tcagcaatca ttcgtattga
    68881 aaatacaatg aagtgtgatc gttcgactgc aaaacacaag cattatttag ctgtagcgag
    68941 attagttgac atggaagtaa tcaagagcaa ataaaaaaag ccggatcgct ccgactgatt
    69001 caataaatcc aacacattta ttatatcaca taaaggagcg gtttgacttg atgcaattgt
    69061 tacgagaggt agatttcaaa cagacaagat gtaatgcgag agatgtgctg aagaactttc
    69121 ggcgtttgga gcggatggca ggtcgctctt tgatagatat taagtcgccg attataacgg
    69181 atatgccgaa ggcaccgaag catggcaata aggcagaaga cgcgattatt cagatgatgg
    69241 atatagaaac ggagagagat gcgattctag cggctttgat ggctcttagt ctgattagtc
    69301 gtcagatact ctactacagc ttctgtgtgc cagatagctt ctcaaactac agaattagcc
    69361 gtgaagtggg ttattcagaa agaagtatac aacggatgaa gtcggaagct ctaatagagt
    69421 ttgcagaagc atataaacac ggaaaaataa ttgcttataa ataatttggc ggttttttgg
    69481 cggaatgatg gcggttttta gacatttacc agtgttatta tggtagtgtc gaaagattag
    69541 gaaacaggat cgacaaaata aacgaaggga ggcaatctcc ctcatcgttt taaacttctt
    69601 cttagataga cagcaactaa ttatgaagaa aaggatgtga attcaactcc tcctaaattc
    69661 ttcatcggtt gctgtttatt ttgattagac agcagcactc acaaaactaa acatgttctt
    69721 gtcgtctttc aactgctgct gtctattaat ttatgtattg gagggaagaa aaatgaaatt
    69781 atcagtagaa ggcactccag aagaaataca agaattgctc caagctattg gtagtagcaa
    69841 ggagcaaaag gtaagtgttt ctaattcaga tattgacggt atttgcaatt gtttaaacag
    69901 agaaaaaata tctaatcctt actaagagaa aatatgttcg ttaatgaatt tccaattttc
    69961 ctctgtagct ctaccttgat aatttttttg cagttcacag atgaataagg aatcgttatt
    70021 atcaagtact gtatttaatt tttcacacat ttgatttgga ttcaaattag ttttaactaa
    70081 ccaaaaagat ttttgtagct ttatatatgc cccaaattct tttattattt caaatacttt
    70141 atcatacttt tgccctgggt tattaagatc ataactaatc atgtagggtt tatacatgtt
    70201 gtcttgcaca tccttgtttt atatttcagc ggaccactcg ctgataaata aaattatacg
    70261 cttagtattt attttcacaa tattaattta tcgtaataac ttttgagtaa atagaacaaa
    70321 aaacctgcac tagtttccgc tagtacaggc agtgactata tcggttgata atctagcata
    70381 tattaaaaat aattgcaaga aaagaaattt atagtggttt ataccaaatt atcaaagcaa
    70441 tgttattttg ttgctgtcta ttgtttttta attattcaca cgataactaa aggtgggtga
    70501 agagaaatga ttccattaat aatttcaatt tttgcgctct gtcttaatgt ctatatgatt
    70561 ggatttaaaa atgggcaaaa taaaaaatag tagcagccaa gaataatttt atagtgtcac
    70621 tgtggcggaa agggtagacg ctaagcatgt gtgctaggtc aatgcttcgg caaccatgca
    70681 aggttcgatt ccttgccagc gacattaaat gcctatgacg gttacgacta ccgaaaaaag
    70741 atcgttaaga agctatacgg tgctacgtac ggcaatgtag taagtgtgct atctgtacac
    70801 caccaagctt cggtcactgt ggcggaagta gaagacgcag cggtaaatgg cgagtagcct
    70861 cgtgagagcc tggtaagttc tcgtgagtgg tgcaatccca ctccagcgac tttaagcaac
    70921 cgaggcatcg gcggtttaaa aatatagggg tgcgcaattt cgtacgcgtt ttgtgcatcg
    70981 tgcaagttac tattacatat tagatcactc tttgagtggt ctttttattt ttgcacaaag
    71041 gaggaaacaa caatgtatag accacaatac ttagaacaga agtatgaagt aatcactgtt
    71101 cataaaggta atggcgaaaa agtatatgag tatagaagac caataaagag cgatacatat
    71161 aaacgaaagg aaaacaatga agttattcca ttgtatggca aaagaatagc taagcattaa
    71221 ataagattgc gaaaggagac ggaacatgac cgaggaattc tatagatggc tattacagtt
    71281 gacaagagaa gatcgtttgg ttaagttcta tcagtctcct aaatggcgca ggcttagaga
    71341 gaaagcgatg aaacgagatc actatgaatg ccaagagtgt agaagactag gtaagtatca
    71401 tagagtagag aacgttcatc atataaagga agtcaaggat agacctgact tagctttaga
    71461 tttagataat cttatttgtt tatgtgttga acatcataat gaagttcatg gcagatatct
    71521 tacagcatta gataaacaag agaagaagat agaaagcttt gctaacttcg atgcaagtga
    71581 aaggtggtaa gtgcatgatc atcaatgata atggcagaga gtatgataca gaaaagattg
    71641 aagagtattc atcttatact cagggattaa ttaaacgttt gatatacgtt cgctatgtag
    71701 gtattaggga tctgttatca gataactgtt gtagtaaata caaagtgaat caagtaagag
    71761 aagcgttgaa taaagataat aacgtcgaaa gaataaaaaa tgtttttgga tatagtattg
    71821 aagagattaa ttattacatt gacttcgctg aagctttcat tccgatggtg agataacccc
    71881 cccttaaaat aaatcgcaaa ttttttgggg gtgatgaaac ggagggggct gtcaggaaaa
    71941 gagatttttt cgaactttat catgaaagga gggctaaaat gtttaaaaac gaattgtctc
    72001 aaaatcgcta cagagaaaaa ttacgccgct ctttaataag ccaattggaa agtcagaaaa
    72061 caaatattga gccattctta gataatgttg atcgttatat cagtttatgg gaaacggcga
    72121 tatcactgga agaagatata tccgagaacg gcattagact ggagaatggt aaaaagaatg
    72181 aatcagtagc gttgcttgtt tctgtcaaca aacaaatggg attgatgttg gataaacttg
    72241 ccattactcc tgaattggta ggtgaagcaa atgaatcaat tcctgagtta taagcatatt
    72301 gaaaattggt tcaaagctat agaagaaggc actatcaagg tatgcaaaga gcaattattg
    72361 ctaaaaaatt atctagaaga aagagtcttt actagagaag atatttactt cgataagcag
    72421 atggtagagg attcaatcaa tataccagca caatactttc cattcgaatt aattccgtgg
    72481 gaaaaatttc tacaatgttt tatttatggt gttcgatgga aaaaagataa aacactagtg
    72541 ttcaatagat atctttcatt aatgggacgt ggtaatggta aaactggttt tgcttcttgg
    72601 aacaacttct ttctactaac cgctaaacac ggtattaaaa attatgatat tgatatctat
    72661 gccaataatg aaagccaagc aaagactagt tttgatgatg tatttaaagt aattaaagat
    72721 catcctgatt tagataaaaa agtatttaaa gctacgaagg aagttattca aaatatcgct
    72781 acaaacagca aacttcgtta taacacggca aatgctagaa caaaagatgg gaagcgacca
    72841 ggtgcaaacc gctttgatga aattcacgaa aatgaagatt attcaatgat aaatgtggct
    72901 acttctggtg gtggtaaaat tcgagattat agagaatttt atgatacaac taatggtcat
    72961 gttcgtggtg gtccgcttga tgacattata gaagaatcaa aaatgattct ttctggagaa
    73021 cttggaattg acaaggatgg agcagaattt tctagtttgt ttccatttat ttgtcgcttg
    73081 gataacgata atgaagttga tgatcccgac atgtgggaaa aagcttgtcc aactattaat
    73141 tacaatgcag atttaaaacg gaaaatgttt caagaatact ctcaaatgca acgtaatgct
    73201 ggtttaagac ttacgttcat gaccaaacga atgaacagac ctatggaaga tacacgattt
    73261 gctgttgctt catatgatga tgttctgcat acgaaagaaa aagaatttcc tgaaaaaatg
    73321 gatgaagtga taggaacagt cgattttgct gatagacgag attttgccag cgttgggttg
    73381 ctaggaaaat acgataaaga tgtttatttt acacaacata cttttatcca cgaatcagcc
    73441 cttcgattac aaaacatcaa acgagaggtt atagatattt ctatagatca aggaaaatca
    73501 cagatcgttc atggaaaaaa tatagaagct gattatattg taggttggtt tcttgaaatg
    73561 agtaataaat attatattaa aaaaatcgct atggatatgt accgtgcaaa aatattgaag
    73621 cccgctttag aagaagcagg ttttactgtg gaaattgttc gaagcggatc tgttacacat
    73681 ggtatgttaa aagatctggt tgatgacctt tttattaatc aacgtttatt ttttggtgac
    73741 gatgcgatta tgcgttggta ttgcatgaat gtatatgaag agcatatttc taatggaaat
    73801 atacgctatg aaaaaataga acctgaaact agaaaaacgg atggcttttt ttcattcctt
    73861 catggtttga attttttaga tgatatttat gattctgctc ctgtaacagt cacaaatagc
    73921 tcagtagaaa atacaggaac tggatttact cctctagtat tctaacttga aaggaggtga
    73981 gaaagtgggg atttttcaaa aggcggtagg atacttcaca aaaaaagcaa cggttccttt
    74041 agaagaatac ttttgtaaat tgcaagttga ttttgtgtat cgaaaatttg cgattgaaac
    74101 ttgtattgat ttgattgcaa atgcgatgag taaagcggaa ttcaagtcat atgaagatgg
    74161 aaaaaataaa aagaatgatc tttactatag gctgaatgta gctcctaata agaaaaataa
    74221 tgcaacagaa tttagaaaaa aactgatcag gagattaata ttctacaatg aagtattgat
    74281 cgtttctccg tctaataatt ctagcgaaat atttattgcg gatagttggg atgtcacaga
    74341 atatgcattg aaagatgatg tgttttctca agtgcaaatt aacaacatag tccttgatag
    74401 agaatttcta gaaagtgatg ttatctatat aaaatacgca gatcaacaaa ttaggcaact
    74461 agtcgatgcg tattatcaag cgtatgggaa actcatttct agtgccatga atgtttacaa
    74521 gcgctctaac gctcgtagat acgtactgaa agggaattta ttccgaccgc aagacaatac
    74581 aacacaagat caaatcaata aaatgatgac atcacaattt aaggctttta tggaagctga
    74641 taatgcaggt gcggtatttc aattacaaaa tgagtacaca ttagaagatt tcagcggaaa
    74701 cttccaaagc aattcaagag atataaaaaa cttaatagac gacatctttg agatgacagc
    74761 agcagcgttt cacgttccga aaaacctact aaagggagac atgagtgggt tatcggatca
    74821 agtggacgct tttttaatgt tcgaaatcat accgattgct gaacttattc aggatgcgtt
    74881 taacgctagt ctctatgaag tagaagaata cttgtcaggg aattttgtac gtgtggatac
    74941 aactatgatc aagattacta gcttcaaaga tttggttgac gctattgatg taggcattag
    75001 aaatggagta tttacaatca acgaaggaag agaacgcgtt ggaaatgatc gctctgataa
    75061 ggcgatggca gatgaaatat ttataactaa aaacaatcaa caagtatcga aaggaggtga
    75121 ggcgaatgac gacaatgaaa acatttctag cagtaaagaa tgaaggcgca gtaccgcaaa
    75181 tttttattca gggatttatt ggttctagtt ggttctttga agggaatact gacaagggaa
    75241 tcaaaaatat tttggatagt ctaggtgatc aagaagaaat tgaagtagta attaattcaa
    75301 acggtggaga cgtatttcaa gggattgcta ttgggaactt acttaagtca aataaagcaa
    75361 aagttaacgt tgtgattaac ggcttagccg ctagtgctgc ttcaattatc gcaatggctg
    75421 gcgatactat aaaaatctac aacaatgcac aattgatgat tcaccgcgct tccacatacg
    75481 gagaaggaaa tgtcgatgac ttccgtacga ttgctgacca actggaatca attgataaat
    75541 cggtaaaggc ttcatataaa acacgattca atggcacaga tgaagcattg caagaacttc
    75601 ttgaaaaaga atcgtttatg gatgcagaaa cagctttgag ttatggattg gtcgatgaaa
    75661 ttatcgatgc agaaaatagc tcaggtactg aagctaaaaa agaacaaagc gttgaagaaa
    75721 ttttgaatga cgttaaagaa aaaagagcag aaaaaattgc tgcatttaca gcagcattaa
    75781 ataaaacatt tggacaagga gatgtaaaat aatgacagtt aaaaatttaa aaggtgtaac
    75841 agctgcaagc gaccaattga tgaaagcttt taaagatggt aacgaagaat cttttagcgc
    75901 agctatggta agcttatcta aggaaattca ggataaaatt ttagaagaag caacagcaaa
    75961 aaatcaagat caattagtat taatgaaccg tggtcagcgt gtattaacta cacaagaaac
    76021 aaaattctat aacgaagtag tgaaaaacga aggttttgca ggggtcgaag aattagtgcc
    76081 agctactgta tttgaacgtg tatttgaaga tttagaacaa tctcatccac tattgcaaaa
    76141 aattactttt gttaacacaa ctggtgtaac agaatggatt gtgtcacgtg gagtcaatcc
    76201 agcatggtgg ggtaaacttt gcgaagctgt taaaaaagtt ttagataatg gctttgatgt
    76261 aattaacatg aagcagttca agctatcagg ttatattcct gtatgtaagg caatgcttga
    76321 tttaggtcca gtatggttag atcgttatgt ccgtactgtt ttagtagaat cattgagaat
    76381 tgcattagaa caagcaattg ttgatggtac tggtaaagat atgccagtcg gaatgatgcg
    76441 tgacatgagc aaacaaacta gcggagaata tgctgaaaaa aaagcagaac ctattacagc
    76501 tttagatgct gtaactatgg gcggtttgat ggcgcgacta tcaaaattca atatcgaagg
    76561 tgtgaatgat ccgatttatc gtaatgtgaa tccttctgat gtggtcctaa ttgtgaatcc
    76621 aactgattac tggtctaaag tattcccagc taagactgta ctaactgcta atggagaata
    76681 cgtacaagta ttgccagtac cagtttcaga tttgcagtca acggctgtgc cagaaggaaa
    76741 agcagttatt ggggtagcct cagattactt catgggtgta ggatctacac taaaaattga
    76801 agcttcagat gaataccatt ttgttgaaga cgaacgcatt tatctagcta aacaatatgc
    76861 aaacggtcaa cctaaacgta acgatagttt cattgtatta gatattagcg ctttgggaac
    76921 tactactaca actacaaaac caacaaccac aacaactaca acacaagcgt aggtgatcag
    76981 aatgaagtat attctttgtc agccggcaat caatcggttt aaatgggagc ttgaagtttg
    77041 tttaactaat ctgaagaaac taggaatcaa agatatcgta ttgcttttca gcagacacga
    77101 tgatcagatt cctatttttt ttgagaagga atatggtgtt gaagttcatg tgtacgatga
    77161 tctgcgggac gacaaagagt atattccttc gattaaacca tatttatggt ggaaatattt
    77221 agaagaagat cattcgcgtg aggacgaccg atatttctat atcgattcgg atgtcatttt
    77281 caataaaaga attaatttgc gcaaattgcc ttctaaagat gatgtttggt attgtagcga
    77341 ctgctgtagt tatctaagtc ttgattatat tagaagctgt gaaaacggag aaaatattct
    77401 aaaagatatg gcaaacattg taaatgttac agtagaatct ttggaaacta taaacactaa
    77461 ttcaggaggc gcacagtggg ttattaaccg tcctaaagcg aattattgga aaaaggttta
    77521 tctggattct aatcggctat atcgctacct tagagggcaa aaaacaaata tacaaatctg
    77581 gacagccgag atgtgggcac agctttggaa catgatgtat ttcaatattg gtcctaaagt
    77641 tcacgaggaa ttagactttt gttttgctac tgatccaata gaaaaagtta aagaagtaaa
    77701 aatcttacac aatgctggag taacaacaaa cgatgaagat ttatttttca aagggagata
    77761 cgtgacttct acgccttttg atgaagattt atcatttgta aacaagaaaa aatgctctta
    77821 cgcatatgtt aaagcaatta aggcggtggt tagatgacgc ctgaacaagt gactgaagaa
    77881 ttgctaatag ctgtgaagga taatatttac gttacctgga acgaagaaga tgagtcaatt
    77941 aaaaagatga tagctaaaaa tgctgtttat cttcaaagta aagtgagtac aacactttct
    78001 ttttctcctg aaagcttaga atacggattg ctaatcgaaa gatgtagata cgactggaat
    78061 cgtgctttag atgagtttga acaaaatttc gctagtgagt tattaggttt cattcaacat
    78121 tatgcgctac aagaatatat tgcaggtgat gtgaatggcg aataatcgta gactcgaaga
    78181 aacattcaac gatggttggt taaagatttt gacgcaaact accaaaagaa atgaactagg
    78241 aaaaaagatt ggtgtagaag atacagaaat cacttcttta aaatttagaa atctttccat
    78301 gagagatagt gatataacag ctatggatgc gatgggatcg aaattaacta agaaagtaaa
    78361 gactccattt catccaatcg ccaagaaatt taataaagat caatatttta tcgtaatcga
    78421 tagtatgcgt tacaacgtta tctatgccga ttacgataat ttttatatct atttttatct
    78481 tgaaagtgtg ggtgaatatg gtgattgata attctaaaga aaaagaacgt ttaaataagc
    78541 aaatttctgc tatcaaaact tccttagaag agcattttgg cctcaaactc tttcaagact
    78601 ccgtaggcga ggatgagcta cctgatgatt ttaattactt cattctcgaa acaggagaaa
    78661 tagaaatgat cactgagcca aaatatagcg tgggtcaaaa tctatatcta actttctatt
    78721 cagaaaatag agaagattta acaggagact cactagatat tatttcattg attcaaaatc
    78781 gttcgattcg ttttcagaga atggatccca atcatttaaa actagagaac caagatcgct
    78841 atatcgatca attggtattt acgtttagac gattattgaa gagtgattgt catggctaaa
    78901 aatagttggg agctaaaaat aaatggacat gatgaacttc ttgtgcggat ggaacgctat
    78961 tcaagcgaga gcgaacgact gattaacgaa gcattgaaat caaaaggttc ggctattgca
    79021 gtggatagga ttacagaaaa aattcctgtt tctgaagcag atttaagaag agggcaccaa
    79081 cacgcaaaaa atagtcgtcc acttaagact caatacatta atttgggttt catcattaga
    79141 cctacaagaa aatttgagta tttaaaatat cctgatttgg ggataggtac ttctaaaaga
    79201 aatcagccgg acgaatttat gagaagagga ttaggtcttg cacttgatcc aattacagaa
    79261 cttctgattc gtcaattcga taaattaaat aaataggggg aacaacaatg gctaaaacaa
    79321 aaactgtagt aacaacgttc gataacgtaa gtatcaaacg aattgctttt aattttaaga
    79381 acgcaggaaa tgcaatcgca acgaattgta atggacaatt agatggcgaa acagaaatgc
    79441 aaacggtggt taaaaaatgt ggagcgacag aagtaaaatc aaaatctaaa ccaatcaata
    79501 tgacggtaac aattactgca catgtaccga tggaagttta tcgacgtttc aatgggttga
    79561 aacaagatgg acgtattaaa ccaggcattt actcttacgg tcctgattcc gtaggcgaag
    79621 atttctcact tgctgcagag atcgtggatg acttcgaaga aaatagaaag ttagttggta
    79681 tgttagcatg cacttcgaat acaggattaa cattctctat tgaaaatggt gcggatgaag
    79741 tagctgcgtt agaactagaa acaaaagtta tgcaagatga atttggtaaa ttttatcatg
    79801 aagcaattgt tgcagaactt gaagaagact taacagatca atggatgacg aatctatctg
    79861 ctgatgtgat taaaaaaact tcagttgtga caactacggc cactcaatca cagtaaaaaa
    79921 aacggaggta gcgaaatgaa cgaagattac tcaaaaattg aactaaacga tggaacaatt
    79981 ttgaatttag aacctaaact gaatatcaag aaattattga tgatcaatag agattttaac
    80041 acagacgagt ttgcaaaaat gactgtggga aaaggatcca tggatatttc tgttattcaa
    80101 ggtgcaaagg ctgtgtatat tgcttaccgc caagcgaaca tgactgatta tatttcattc
    80161 gatgaattta tcgataaatg ggattttgat atggctactg ccagctatat ttatcaattg
    80221 atgatgttca aacaagcacg cgatgcttat caaaaagaat ttgaaaaagc aaataaggaa
    80281 aaaaagcttc aaaagtaaaa attccaaagc tcttagttga aacgtgggtc gatgtctatt
    80341 cgatgttgac cgacgttttt tctatgcctt cagatttggt tttaagcgat atctgtttag
    80401 atgacatttt gcaaatggct tacaacaaga gtgcttatga aggatggaaa aactatgcaa
    80461 taaaccaatc ccagaaaaac taaagaaagg aggtaaaaaa tggctaaaaa gagaacagaa
    80521 gcagaagtaa ctttcatagc taacgatgac ggattgaaat ctacgttaaa agaaatcagt
    80581 gctgaattaa ctaaaaatag agcagaatta aaactagaac aagctcaatt acaacagact
    80641 ggttctgaat cagacaagtt aggaagtaaa ttatcttctt tagaaaagca gtatgaatta
    80701 caaagtcaaa aagttgaagt aactagccaa cgtttagcca atgcgaaaaa atattatgga
    80761 gaaaattcca ccgaagttca gaaacttgaa agagaactga ttaatcaaca aacagcgcaa
    80821 caacgtttgt caaacgaaat tgataaaacg agtaatgcac tagctcaagc aaaaggcgaa
    80881 atacagacgt acgagtctac aatgcaacag ttggatagcg aacaaaaaaa tgttcaagct
    80941 agtgcttctc tgattgaatc cgaatacaaa aaatggcaag caactgctgg tcaatcagct
    81001 tctgaagccg agaaattagc gaaagcccaa gaatatgttt ctcaacaatc tgaaaatgcg
    81061 gagaaaacga tagatatcct aagacgacag ttagaagcta cacagtctga atttggcgct
    81121 acatccacag aagcaatgca gatggaagcg aagcttaatg atgctgaacg tgaatttgaa
    81181 gagttaggac aagctgctaa aaatgtagat acaactaact tggacgatat cggaagcaaa
    81241 atagatatga ataatttaat ggaagcttct gacgttttaa gcgacattgg cgataagctt
    81301 acagaattag ggaaacaagc agtggactct gctaacagtg taggtagttc ccagagtaag
    81361 atacaagcta attttggttt gtctaaacaa gaggctgaag aattaacgaa tgtagccaga
    81421 gacatttatt ataaaggttt tggagaatcg ttagatcagt ccacagatgc attgattttg
    81481 gtaaagcgta atttaggaga tttaaataat caagatttac aaaatatcac ggaacaagct
    81541 atggtcctag aaaacaccat gggcgctgat atggatgaaa cgttacgtgg tgtaaatggc
    81601 ttaatggtca atttcggctt gagtgctcaa gatgcaatgg atttaatggt ttcgggtact
    81661 caaaacggtt tagataaaac gcacgaatta ggcgacaata tggcagaata tagccaatta
    81721 tggagtcaaa tgggatattc agctgatgaa acgttcggaa tgcttcaaaa tggtttagat
    81781 gcgggtgctt ataaccttga taaagtcaat gacttagtta aggaaatggg aatatcgtta
    81841 acagatggtc gatttgagca aaacatggat atgtttagtg aaagtactag aaaagctttt
    81901 gaagagtgga aaaatggcgg aggaacacaa aaagacgtta ttaattccat gattcaagat
    81961 tttagcaata tggatggtca atacgaccaa ttaaataaag cttcgacaat ttggtctgcg
    82021 cttggcgaag ataatgcgat gaaagttgtc caatctttaa ctgatgttaa ccatacattt
    82081 gatgatgtta gtggatctgc acaaaaaatg aatgaagatt ctactactcc gttgcaagag
    82141 ttgaacggga aaatagctga attaaaggat tcattagctc ctataggcaa cacaatcata
    82201 gatgcactcg aaccagtaat tgattttcta ggaaagatgg ctgatgcgtt taataatctt
    82261 ccacaaccag tacaggattt cattgttgct ataggtggtc ttacagcagc atttggcata
    82321 ctgttaccgg caatactagc cgtgtcatat ttatttggtc cgatgatgct tataattgga
    82381 ggaattatag ctgttatagc aggcgttatt gtggcaatta agaactgggg tgcaattact
    82441 gactggttta gtggtttatg gaaaaaattt actgattggt tgggtgatac ttgggaaagt
    82501 ataaaagacg gagcctcatc agtttgggat ggggttaaag aaacctggtc tggatttgta
    82561 gattgggttc aagatatttg gcaaggagtt tctgattggt ttggagagct atggagcgga
    82621 ttagttgaag gagcttccaa catctggcaa ggagtccaag aaacttggca aacattcgtt
    82681 gattgggttt caaatatttg gaacggagtc aaagaagtat ggtcgattat ttgggcagac
    82741 attgtaggaa ttgttcaaat accatggaca ttaataacgt cattgattca agctggtatt
    82801 aatattatcg tgggtatttt tgatgtagct ggacagttat tgggcgcagc ttggcaagct
    82861 gtttggacac ctatttctga tttccttaaa aatacttggg atactatgac acaatggata
    82921 agtatcgctt ggaatgggat tgtaactaca ttccatacta tatttgatcc agtagtggca
    82981 tggtggaatg gtatatggac agctattagt actacggctt caaatatttg gaattcaatt
    83041 agtgcaacag cttctagtat ttggaacagt atcaagaata caatcactag cttggtacaa
    83101 gcagctgcta cagtaattca aaatatttgg tcaactgtat ctagttggtt aggtggaatt
    83161 tggaattcaa tcagctctac agcatcaaat atctggaata gtgtgactag tagtataagc
    83221 aatgctataa acgcagctaa aagtgccatt caaagtgttt ggaatagtat atcttcgtgg
    83281 attagcggaa tttggaacgg tatcaaaaat actgctttga atctttggaa tggaattaca
    83341 agcactatta gctctaaagt aaacgatgga aaaaatgcaa tttcaagcgg ttggtccaat
    83401 ctaacaggta ttgtttccga catattcaat aatgttaaaa gtacaattgc taacatatgg
    83461 gaaggcatca aaaagactgt tagcgctcca attgattgga ttagagacaa aatcagtggc
    83521 atttttgata atttgaatat ttctatacca catattccgt taccggaatt tatcatggaa
    83581 ggcagcttta acccgctaaa aggtcaaatc ccccatttgc gtgtaaaatg gcatgctaaa
    83641 ggaggtatct ttactaaacc aactttacta ggtggaatga acggtgtcgg tgaagcagga
    83701 cctgaagcag ttttaccttt gaaaagatct gttttgcaag aaattggtga tcgtatcttg
    83761 agtagcacat cagtttcatc tagggcacaa acgattcaac ctgtgaataa ctacgaattc
    83821 aatttcacaa ttgatggtaa cgcagatgag gttactatga agcaaacaac tcaacaaatc
    83881 attgatagca ttacaaaaat tcaaaatgat aatgcttcgg catggcgtta aacaggagag
    83941 tatttctcct gtttttttag tattaaaaag gatgtgaaaa aatgactgat tgtatacatt
    84001 ctataatcga tggatttcct gattatttgc ataaattggc tttagctgaa agaccaacca
    84061 taccttctcc aaaaagacag agagttgaaa cttctgtttt aggtaggtta ggtggcttag
    84121 tacaagatta ctcgtttgaa gatatgtcgt ttacattgca ctataactat ttagaggatg
    84181 tggaagacca tcaagcgttc aagcaatcgt tttatatcat gcgtcattgg ttaaactatg
    84241 caaagaaatt agaattctct gacgatccca acgtctatta cgttatccag actatcgata
    84301 ttggggatgc agaaaacgat attgttgaat ggggagagtt cgatgtaaat attactgcga
    84361 aaccattcgc aagagttcaa gaagatgtac ctataaccgt agataaacca cagtcattta
    84421 acttgctgaa taatagttta gaagaaagtt ttccaaagat tatcatcact ccttcagcta
    84481 cttcatgcca gttcatctta aatgattatg tgtttagttt cgaaggctta gtagcaggaa
    84541 ctgatgtagt cattgatagt gatttgatgc tttgctacga agagcaatcg gacggagata
    84601 ttttagatcg gtccaacaaa atgaagacca tgcaatatcc gacattgcaa gtggatatca
    84661 atcattttaa ttgcactggt ttgagcaaaa tacaaattta tcgtaacggg ttaaggtagg
    84721 tgaaatagat gatcgataat ttaataacta tttacgataa aaatgacgcg aataatttag
    84781 ctgaacattt atatgatacg caaggtttag gcgctttgtc agactggtta acagctactg
    84841 ttagcaataa actaaacgga gccgagatat ttcagggtac ttattcaata aacggaacta
    84901 atgcagattt gattgtagac ggacgtatta ttcagtgtta tgtagatgaa aatcgagcaa
    84961 aacagcgtct acggatttat tatgcaaaaa cttctgtaat aggcaatacg atagaagtaa
    85021 aagctgaacc tattttcaat gatataagaa aatcggtgtt gaataaatat gacagcggaa
    85081 cagaaaagat cactgctact caggcatggc aaaacgcaaa agttttagcg aaaccagcta
    85141 tcccttcgca gttttctttc tcgtcattag tagatacgct tgctaatgtg aagatagaaa
    85201 aggcgaattt tttagaattc tttggtggaa aagagggatc tattctagat cgatttcatg
    85261 gtgagtttct aaaagataat aacacattac gtcatgaaaa aagtctaggt acggatcata
    85321 aaatcaaagc gatttatact aaaaacttaa ctggtcttga cttagagatt gatgctcaaa
    85381 gtgttttagt tggagtttat ccattcatta gcagctcttc agaaggagaa gacgagatca
    85441 ctctaccaga agaagttatt ttcacggatt acgtggatga ttatcctgct ggatatgttt
    85501 cttttgttga ttttaaagac aaagcgactg atgtagccac attaagggaa gctgctaaag
    85561 actggttgaa aacaaacata gataaacaaa aaccacaagt gagtggttcg attgaattag
    85621 taccattgag gcatcaaaga ggctatgaaa aatttgttga tctagaaaaa gtttcgatgg
    85681 gtgacggagt agatgtgtat catccacagt taaaagtgaa tatgtcagcg agaattgtgg
    85741 aatatacgtt taatgttcta accaattcat acgataaatt agttgtagga aacgtcaaaa
    85801 caaacttctt agaaaacaca gagaataatg tcagcaattt gattaatgat gccattgatc
    85861 aattgaaaaa cggtggcgaa atcagtgatt tactcaatga tattgtagat catcaaactg
    85921 atatgattac tggtcaaaat ggtggttatg ttttattaga tcctaaagaa gcgcctagtc
    85981 gtattttgat tatggacaca ccagataaga ataccgcaag gaatgtttta caaatcaaca
    86041 atgctggtat tggtttttct aaaactggca ttaatggaac atatgaaacg gcatggacgt
    86101 tagatggcgg attcaatgcc tcgtttatta cggctggtga aatagtagga attactatta
    86161 gaggtactac attaattagt gatggtgctg attatagaac aagtattgct aatggcaaaa
    86221 tgacttggta ctcaaaaaaa gttaacaaag atattatgga gctagaagca cgtgattatg
    86281 taagtgctga tgccggtatt gtatcataca ccatgaaaac tggtggtggt ttcatgatta
    86341 gaaatccaca gggtaacttg gtttttagta cgtgggataa tggtaataac agaccgtttc
    86401 tatcttttgg tgcgcccaat ttcaggtata gcaatgctag ttatgtaact tctggcgacg
    86461 gtagttcttt aagcattaat ggtagtgcgg gtaactcatg ggaatttaag gtagctggta
    86521 ggactatgaa atttactagt gatggtatgc taacgttacc aggttgtttt tttggttcat
    86581 gggaagatgg gaaacttgct aggtttgaac aatcaacggt acaagtatat aaagatttta
    86641 ctgttagagg tactaaaaac tcaactgtac caacagaaca ttatggacaa cgactattga
    86701 acgcttatga aactccagaa tattatttcg ctgattatgg ggaagccgtt acaggtgaca
    86761 atggtaaagt tcgtgttgat attgacccca tgtttgctga aacagtaaat ctaagtcggt
    86821 atatgacaca tgtgacacct acagaactag ttttgtgtgc tgttactcat gaagatattg
    86881 accatttcat cattgaaact agtaagccaa acgtattagt tagatggaat ttagtggcac
    86941 accgtctagg gtatgaagat attagattaa aagaggatac agcatatgat agcacagtgc
    87001 ttgaccaaaa acgtttttaa aacgaagaca aggaggtata taaatggcta gcagtttata
    87061 taatttggct ttagatttca gcaaagaatt aaactacacc aaagctatta tggctcgtca
    87121 aggtgataaa gggattacgg tgacggttaa accgtttcta aatggcttgc agatggatac
    87181 gagtggcgga acatttactt taaaaggaac aacaccatct aaccgttacg tagataatgt
    87241 tgcaactagt gtaactagtg aagaagtcac gttttctctt gatggcacat ttatgagtga
    87301 agcaggatat tataaacact gctacgtaga atatagaaaa gacaatcaaa ttttaacaac
    87361 gcaagatatc atttttttct cactaggagt gtctgacatt tcgcaaggcc aagccgatga
    87421 atatgtttcg caattagaag agttgattcg aaagtacaac gaaacttttg atgcttttat
    87481 ggctgaaatc aaaggtagag tggatagctt aaatcaacag attactgatt taactggtca
    87541 agctaaaacg ctacaagaca agttagatgc tctgaaagaa gaaatttcta agttaggtaa
    87601 cttacaagtg atgtacagta acagcatcga cttcggggac tatgattatt cggagaaccc
    87661 gaatttaatg ccatatatta cagaaccttg ggttggacct ttgttaggta atggacatac
    87721 agttaaagat agtgttaaaa gggttataac tcatactaaa actagaacag ctaattccgg
    87781 cgacatatta tcgcttggct taggtattcc gtgtacagcg gaagctaata ataggtatct
    87841 tataaccact ttacgaccat ctacgacata cacattaagc gttactatga gtgtcggttc
    87901 agattggact ggagagacca atactatagg ggttaggctt agatatttaa atgaacaagg
    87961 tggtatagaa ctgcccatta atgcattaat accagcaaat gtagaacgcg ataaaatggt
    88021 cactcataca tttactggta taacaaaaga taatgtaact agcataacaa actgttatgt
    88081 tgaaatattc tcacttaata gtgaatataa aggaacggtt agtgtcagct atgacgttaa
    88141 gttaaaagca cactacccta acttactaga tggcccttac tggttaggta aagttccttt
    88201 aggcgagaat attgctgacc ctacagttgt ctttccacac aaaactagtg aatatatggt
    88261 ttatggtaga cgcaatacag aaaactatat cgctgaccaa acatatacca tatcaatgaa
    88321 agcaactaaa ctaacagttc aatcgtttgc cgtgtatatt gctgctggcc gcgttaaagt
    88381 aggagacatg aagcctactg aggggttagc taatacatgg gagttaactt ttactgtaac
    88441 taagcaacat atagatagtg gggtaactaa ttatctggaa atataccaat acccgtcagc
    88501 tacaaaagga gctgttcaaa ttgagtggct caaactagaa aaaggcaata ctcgaacccc
    88561 gaatattagt gagtataaat atcgtggtac tggtatgcgt gattcaaaca atccaaaaga
    88621 ttatgtttgg gatctagcac cagaatatgt cgaagataat ttggccacag atattaaaat
    88681 ttctgaaatt actggtaaag caaacaatta taccgatggg aaagtatcgg agattaattc
    88741 gcagttgact gcttcaatta atgaagtaga caccacagct aaggatgctc aaacaaaagc
    88801 gaatgctaat gcgactgcta tagatgaatt agacaataag atcgatgaac gcattaatga
    88861 tacagctact accacattaa cagttacaaa cgggaatacc ggatcagcaa agctttatcg
    88921 tgaaggaaaa acagtttcta tatattttgt ggctttaaac ggaaaaagca gtggtggaaa
    88981 tgattcaacg atactaacaa ttccagaagg ctatcggcca ccaattagtt ttgagcaact
    89041 ggttggctcg atagaccgtt ctactttgaa cagtgctcag ttatctattg gtgcagatgg
    89101 agccattaaa tggcgaagaa actcaagtta tggatcggat tatacctttg caattactta
    89161 cacgatttag aaaagcgtga atcgatatga aggcagcata tagaccaatt gaaccttacg
    89221 gattcgagca aatcattgtg aatgatgaag aacatttacc ggaagaatgc acagaagtcg
    89281 aaccaccgat tccaaattgg aaaccgaaat tcaattactg ggagggaaat aaatgaaaaa
    89341 catttggaaa tatggacgta ctggcggaga gtacgcagga aaagtattgg acgacatgct
    89401 tgtatccgtt ccttacacag atcagccacc gcttgaagga attcgtgctg atggcgaacc
    89461 gttaacaatc gctgatcaaa tgtttgatcc taaattgaat caatggatta ttttagcgaa
    89521 cgcactagat cacaacgatt taaacaatct caaagcaatg tatgagtcgt tagaaaatga
    89581 gaacggcgat ttaaaacaga tcaatgccaa actcatgcta agcgatgtag caattaaaca
    89641 ggaaaatact gcattgaaag aaaaagcgga tagtttagca caaatcaatt caaaaatgat
    89701 gcttgcttcg ttacaaaata gcaaagacat ttcagaaatt aaagagcaac taaatccagc
    89761 ttcaaaggga ggtgagtagt atgtttagtt ttagcgatgt gaaaatgatg tatgattggg
    89821 gctgtttcac taacgaacaa gtaatggttt tcgttccgtt gtgcattact gaagaaaaag
    89881 cagataaaat cattagcaaa gaagagagcg catcttaatt gatgtgcttt ttattttgat
    89941 tcaaggagtt gtcacatgat taatttaggg gaatggggag cgatagcagg atcaataacc
    90001 gctatcgttt ctttgatttt attagtaata aaaccaatta ctgcatcttt ctcgaagatt
    90061 actgagactc tttcaaaagt aagtcacaat ttagatttgc tgactaaaga tttagaatcg
    90121 agcaaatcag atcgattgat gattcatgaa gaactaaaga aacacgatga aagattagat
    90181 acacatgcag aaaaattggt agaacacacg caacaaatta aaactttatt tagggagaga
    90241 agaaaatgaa taataaaacg ttcgaagtac taaaatggtt cgcactggta attattcccg
    90301 cactagctac tttcgtgggg ttagttggta aagcgctcaa ttggcagtac acagatatct
    90361 gtgttgtcat cattactggt tttggcgcgt ttttagggag tgtgttgggt gtatcaaatc
    90421 gaacctacaa aatgttctcg gctgaaagcg aagaaggagg aaacaaatga aaaagaaaat
    90481 tactattact gcgatgagcc tgttaacggc tcttttttta ttacccatta atacgtttgc
    90541 ttatactatt aatgacgagt ataatttagc gccgaatcaa ggagactcca gattagcaat
    90601 tcctaacaaa attattttgc acgaaactgg aatagatgca ccagcaagaa acgtagccgc
    90661 caacatgaaa aataattata acggaagcaa ttcttatact acagatgtta ttggtgacgg
    90721 tgggattgtt taccgtgtgg gtgagcaagg atatgtttcg tggggagctg gtaacgctaa
    90781 tccttatgcg cctgtacaga ttgaattaca gcgcacatat gataaagcat tgtttgaaaa
    90841 aaactatcga gcttatattg aatatacaag agatagtgca aaaaaatatg gaattccatt
    90901 gactcttgat caaggaactt ctttatttac aaaaggaatc atttctcatt tgtgggtgac
    90961 aaattatgtt tgggggaacc acacagatcc atatggttac ttatcgcaaa tgggagttag
    91021 caaagaaaag cttgc
//
LOCUS       DAPBCF010000007        76553 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.007, whole genome shotgun sequence.
ACCESSION   DAPBCF010000007 DAPBCF010000000
VERSION     DAPBCF010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 76553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76553
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.007"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..606
                     /locus_tag="RD508_000623"
     CDS             <1..606
                     /locus_tag="RD508_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735246.1"
                     /translation="IQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWDTFLHAFSGF
                     LAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSADKLLQFDMQ
                     KDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGYLDVGIMDTM
                     KDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(781..1350)
                     /locus_tag="RD508_000624"
     CDS             complement(781..1350)
                     /locus_tag="RD508_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7735247.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(1433..3493)
                     /locus_tag="RD508_000625"
     CDS             complement(1433..3493)
                     /locus_tag="RD508_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HDT7735248.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(3770..5248)
                     /locus_tag="RD508_000626"
     CDS             complement(3770..5248)
                     /locus_tag="RD508_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7735249.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(5546..6481)
                     /gene="murB"
                     /locus_tag="RD508_000627"
     CDS             complement(5546..6481)
                     /gene="murB"
                     /locus_tag="RD508_000627"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDT7735250.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(6554..7474)
                     /locus_tag="RD508_000628"
     CDS             complement(6554..7474)
                     /locus_tag="RD508_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7735251.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDKPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            7587..8339
                     /gene="xth"
                     /locus_tag="RD508_000629"
     CDS             7587..8339
                     /gene="xth"
                     /locus_tag="RD508_000629"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDT7735252.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            9203..9736
                     /locus_tag="RD508_000630"
     CDS             9203..9736
                     /locus_tag="RD508_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HDT7735253.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(10226..10750)
                     /locus_tag="RD508_000631"
     CDS             complement(10226..10750)
                     /locus_tag="RD508_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7735254.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(10743..11216)
                     /gene="tsaE"
                     /locus_tag="RD508_000632"
     CDS             complement(10743..11216)
                     /gene="tsaE"
                     /locus_tag="RD508_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDT7735255.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(11339..12319)
                     /gene="pta"
                     /locus_tag="RD508_000633"
     CDS             complement(11339..12319)
                     /gene="pta"
                     /locus_tag="RD508_000633"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDT7735256.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(12472..13152)
                     /locus_tag="RD508_000634"
     CDS             complement(12472..13152)
                     /locus_tag="RD508_000634"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDT7735257.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            13278..14147
                     /locus_tag="RD508_000635"
     CDS             13278..14147
                     /locus_tag="RD508_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7735258.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            14173..14688
                     /locus_tag="RD508_000636"
     CDS             14173..14688
                     /locus_tag="RD508_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735259.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(14735..15328)
                     /locus_tag="RD508_000637"
     CDS             complement(14735..15328)
                     /locus_tag="RD508_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7735260.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(15353..15532)
                     /locus_tag="RD508_000638"
     CDS             complement(15353..15532)
                     /locus_tag="RD508_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735261.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(15609..16118)
                     /locus_tag="RD508_000639"
     CDS             complement(15609..16118)
                     /locus_tag="RD508_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735262.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(16214..16594)
                     /locus_tag="RD508_000640"
     CDS             complement(16214..16594)
                     /locus_tag="RD508_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7735263.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            16924..17673
                     /locus_tag="RD508_000641"
     CDS             16924..17673
                     /locus_tag="RD508_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HDT7735264.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(17857..19134)
                     /locus_tag="RD508_000642"
     CDS             complement(17857..19134)
                     /locus_tag="RD508_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735265.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(19213..19857)
                     /gene="pcp"
                     /locus_tag="RD508_000643"
     CDS             complement(19213..19857)
                     /gene="pcp"
                     /locus_tag="RD508_000643"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HDT7735266.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(20056..21000)
                     /locus_tag="RD508_000644"
     CDS             complement(20056..21000)
                     /locus_tag="RD508_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HDT7735267.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(21002..21688)
                     /locus_tag="RD508_000645"
     CDS             complement(21002..21688)
                     /locus_tag="RD508_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HDT7735268.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            22162..22482
                     /locus_tag="RD508_000646"
     CDS             22162..22482
                     /locus_tag="RD508_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HDT7735269.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            22636..23541
                     /locus_tag="RD508_000647"
     CDS             22636..23541
                     /locus_tag="RD508_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7735270.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            23538..24311
                     /locus_tag="RD508_000648"
     CDS             23538..24311
                     /locus_tag="RD508_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDT7735271.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(24492..25916)
                     /locus_tag="RD508_000649"
     CDS             complement(24492..25916)
                     /locus_tag="RD508_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7735272.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            26127..26573
                     /gene="nrdI"
                     /locus_tag="RD508_000650"
     CDS             26127..26573
                     /gene="nrdI"
                     /locus_tag="RD508_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HDT7735273.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(26638..28620)
                     /locus_tag="RD508_000651"
     CDS             complement(26638..28620)
                     /locus_tag="RD508_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7735274.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSAATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(28634..29530)
                     /gene="murQ"
                     /locus_tag="RD508_000652"
     CDS             complement(28634..29530)
                     /gene="murQ"
                     /locus_tag="RD508_000652"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDT7735275.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(29533..30594)
                     /locus_tag="RD508_000653"
     CDS             complement(29533..30594)
                     /locus_tag="RD508_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDT7735276.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(30805..31332)
                     /locus_tag="RD508_000654"
     CDS             complement(30805..31332)
                     /locus_tag="RD508_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7735277.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(31399..32901)
                     /gene="eat(A)"
                     /locus_tag="RD508_000655"
     CDS             complement(31399..32901)
                     /gene="eat(A)"
                     /locus_tag="RD508_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HDT7735278.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKSQPKHLSISYVRQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(33159..34280)
                     /locus_tag="RD508_000656"
     CDS             complement(33159..34280)
                     /locus_tag="RD508_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDT7735279.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPHGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            34405..35346
                     /locus_tag="RD508_000657"
     CDS             34405..35346
                     /locus_tag="RD508_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDT7735280.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFRSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKTAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYNPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(35496..36392)
                     /locus_tag="RD508_000658"
     CDS             complement(35496..36392)
                     /locus_tag="RD508_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HDT7735281.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFNMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLAYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPIPSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            36661..38001
                     /locus_tag="RD508_000659"
     CDS             36661..38001
                     /locus_tag="RD508_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7735282.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVIVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            38219..38662
                     /locus_tag="RD508_000660"
     CDS             38219..38662
                     /locus_tag="RD508_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HDT7735283.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(38927..40345)
                     /gene="nhaC"
                     /locus_tag="RD508_000661"
     CDS             complement(38927..40345)
                     /gene="nhaC"
                     /locus_tag="RD508_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDT7735284.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPKLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(40748..41971)
                     /locus_tag="RD508_000662"
     CDS             complement(40748..41971)
                     /locus_tag="RD508_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDT7735285.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKEGFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVEQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(42002..42841)
                     /locus_tag="RD508_000663"
     CDS             complement(42002..42841)
                     /locus_tag="RD508_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDT7735286.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETTVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNAALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDEKNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(42858..43538)
                     /locus_tag="RD508_000664"
     CDS             complement(42858..43538)
                     /locus_tag="RD508_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7735287.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(43540..44613)
                     /locus_tag="RD508_000665"
     CDS             complement(43540..44613)
                     /locus_tag="RD508_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7735288.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IIEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRQKALDYLIKS
                     GVKINILQKNELDSRIKVIEGGR"
     misc_binding    complement(44669..44907)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(44949..45182)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(45259..45930)
                     /locus_tag="RD508_000666"
     CDS             complement(45259..45930)
                     /locus_tag="RD508_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7735289.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYFDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLD
                     KKTEK"
     gene            complement(46017..48695)
                     /gene="mgtA"
                     /locus_tag="RD508_000667"
     CDS             complement(46017..48695)
                     /gene="mgtA"
                     /locus_tag="RD508_000667"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HDT7735290.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLTFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASMFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGKFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQQVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNVTFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIHRFQELL"
     gene            49354..49791
                     /gene="ndk"
                     /locus_tag="RD508_000668"
     CDS             49354..49791
                     /gene="ndk"
                     /locus_tag="RD508_000668"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HDT7735291.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAVDAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(49813..50679)
                     /locus_tag="RD508_000669"
     CDS             complement(49813..50679)
                     /locus_tag="RD508_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7735292.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICSKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLSLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEKKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(50839..52233)
                     /locus_tag="RD508_000670"
                     /pseudo
     CDS             complement(50839..52233)
                     /locus_tag="RD508_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
     gene            52328..53287
                     /locus_tag="RD508_000671"
     CDS             52328..53287
                     /locus_tag="RD508_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7735293.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLSGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            complement(53296..53997)
                     /locus_tag="RD508_000672"
                     /pseudo
     CDS             complement(53296..53997)
                     /locus_tag="RD508_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
     gene            complement(54473..55096)
                     /locus_tag="RD508_000673"
     CDS             complement(54473..55096)
                     /locus_tag="RD508_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735294.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(55255..56652)
                     /locus_tag="RD508_000674"
     CDS             complement(55255..56652)
                     /locus_tag="RD508_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7735295.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHPEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(56684..57655)
                     /locus_tag="RD508_000675"
     CDS             complement(56684..57655)
                     /locus_tag="RD508_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7735296.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKELLEKGVTAIFVSNYNMSIGAIECFNQEGIRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGEQAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            58029..58454
                     /locus_tag="RD508_000676"
     CDS             58029..58454
                     /locus_tag="RD508_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735297.1"
                     /translation="MKKLIVLFILSAGLLTLTGCNLFGGSDQSSDETTDSSVLKAEKA
                     DITNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQETDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKEATITFTKIGNYRLKDEDGNIYSL"
     gene            58540..58713
                     /locus_tag="RD508_000677"
     CDS             58540..58713
                     /locus_tag="RD508_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735298.1"
                     /translation="MIDSPDYCTCNNNKNIHTEFNDQGSLSICDNCHKLVKDSFKTFE
                     SYPVQNYVKSRRR"
     gene            complement(58951..59652)
                     /locus_tag="RD508_000678"
     CDS             complement(58951..59652)
                     /locus_tag="RD508_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDT7735299.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(59668..60108)
                     /locus_tag="RD508_000679"
     CDS             complement(59668..60108)
                     /locus_tag="RD508_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HDT7735300.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(60108..60683)
                     /locus_tag="RD508_000680"
     CDS             complement(60108..60683)
                     /locus_tag="RD508_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HDT7735301.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(61531..62010)
                     /locus_tag="RD508_000681"
                     /pseudo
     CDS             complement(61531..62010)
                     /locus_tag="RD508_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(62169..62870)
                     /locus_tag="RD508_000682"
     CDS             complement(62169..62870)
                     /locus_tag="RD508_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7735302.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(62978..64420)
                     /locus_tag="RD508_000683"
     CDS             complement(62978..64420)
                     /locus_tag="RD508_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003243232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7735303.1"
                     /translation="MQSRFSEKFLWGGATAANQLEGAYDRDGKGLSVADAMPGGKQRF
                     AIIGSEEFDWTIDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPN
                     GDEGTPNEAGLEFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYE
                     RFAQTVLERYSSKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVA
                     SSKAVKIGHELRSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGE
                     YPAYTARTHKKYGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSE
                     GNLLGGVKNPFLEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDG
                     TIIDDYRIDYLRRHIEAMANAVADGVDLMGYTPWGCMDLVSASTGEMSKRYGFIYVDL
                     DDEGNGTLNRSKKKSFDWYKEVIASNGVNL"
     gene            complement(64434..66300)
                     /locus_tag="RD508_000684"
                     /pseudo
     CDS             complement(64434..66300)
                     /locus_tag="RD508_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
     gene            complement(66421..67273)
                     /locus_tag="RD508_000685"
                     /pseudo
     CDS             complement(66421..67273)
                     /locus_tag="RD508_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            complement(67583..68296)
                     /locus_tag="RD508_000686"
     CDS             complement(67583..68296)
                     /locus_tag="RD508_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HDT7735304.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            complement(68364..68690)
                     /locus_tag="RD508_000687"
     CDS             complement(68364..68690)
                     /locus_tag="RD508_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HDT7735305.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            complement(68812..69060)
                     /locus_tag="RD508_000688"
                     /pseudo
     CDS             complement(68812..69060)
                     /locus_tag="RD508_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(69361..70614)
                     /locus_tag="RD508_000689"
     CDS             complement(69361..70614)
                     /locus_tag="RD508_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDT7735306.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            70675..71415
                     /locus_tag="RD508_000690"
     CDS             70675..71415
                     /locus_tag="RD508_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7735307.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(71501..72259)
                     /locus_tag="RD508_000691"
                     /pseudo
     CDS             complement(71501..72259)
                     /locus_tag="RD508_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
     gene            complement(72256..73284)
                     /locus_tag="RD508_000692"
     CDS             complement(72256..73284)
                     /locus_tag="RD508_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HDT7735308.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKAYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            complement(73304..76474)
                     /locus_tag="RD508_000693"
     CDS             complement(73304..76474)
                     /locus_tag="RD508_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735309.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLYYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSIPE
                     NQLFAGDVLEIVLNDQAGEAAAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATK
                     IVVEGGLSFLAPSKLDCGQIKATGLTQEAFGQMDIQEKLWIYDQRETKSPWILTIKLS
                     QPFTTDAGFSMQDVLYFKKAEEYQLVNEEELEIVRGQNSTNVQTDYSEYLNNGRAFKL
                     VLTKENQIAGNYSAEMTWTLADAPTE"
BASE COUNT        22091 a        15836 c        13235 g        25391 t
ORIGIN      
        1 atacagattc caaatatgct agaaatcatt ttgttatctt ttatttttag ttcaacagtt
       61 ttaggagagt taagtgattt ttatggctat ttttcaatgt gggatacttt tctacatgca
      121 ttcagcggat ttttagctgg gggtgtcggc ttttcccttg tttatttgct caataaaaat
      181 acaaaaacca tgaacttgac tcctttatta ctagcagttg tttccttctg tttttcgatg
      241 acagttggtg ttatgtggga gtttgtggaa ttttcagcag ataaattact gcaattcgat
      301 atgcaaaaag atacgatcat ccagcaaatc aatagtgtgg agttaagtaa agacggaaac
      361 actgtctatc atgttccaga tatcactcgg acaatcattg aaagtcaaaa tgcagatggt
      421 aaaacagata aaacaatcat ccaaaatggt tacttagacg tgggaatcat ggatactatg
      481 aaggatttat ttgttaattt tattggagca gttgttttca gtgtatttgg ttacctctat
      541 agtcgaaacg attaccaaaa atttacgttc atcaagaatt ttattcctaa aaaaatcaaa
      601 cgataaaaca tgctaaaaaa caagagaagg ggcagtgaca atacttttgt cactgcccct
      661 tcttttttga atgtatggca tgccattagt tatccgatag tattaactca aaaaagtaag
      721 atatgaggaa tgactatttc gttttttatc ccaatactga ggacttattt caccatttcg
      781 ttatttatct aatttactta aaacctgcat aactttttca taatctggat taggtgtgcc
      841 gtctagattt tcagcaataa aagtaaaacc cattttttta taaagagcaa tcgcctgatg
      901 gctccatgtc tgtgtgtgaa gatagattgg tccgtccgta tggagggtag gaaattcttg
      961 caagactctg gcagtcaatg cttttgcgag cccttttcct tggtaatctg gtttcactgc
     1021 taaccaatga aaaaccggat acacttgctc tcttgatttt tttcgccaag cggtacaggt
     1081 tgctactttt tctccttttt ttgtctctac aaaaaacatc cttctttcaa gttcttcagg
     1141 ataaggagca aagttttgtt gaaaatactc aagtgcttca tctgtcgttt gaaattcccc
     1201 aacggaagtc tcaatctccg cccaagcaga ttcatcttct ttttgataaa atcgaaattc
     1261 aaaaccttcc gctaaaggcg tgattggaac attttgttga agtggtcttg tcatccagat
     1321 ttctgcgtaa ggtaacgttt tatctaacat ttttctatcc ctcctcgtct ccattatgcc
     1381 aaataacata tgactcagct acttatttga ctataacaga tagagatata aatcagaacc
     1441 agtcatctgc gtcaaattca tttcgattag cgtataccca tgttcctgcc atacctcgca
     1501 tgaaatctcc taaagcagaa gaaggaatac ctccaccagg tgcgggtgtt cccggactag
     1561 gaagtggtac ttgcggctgc agatgctcat cggtggaatc aatagttgac aagcgttttt
     1621 tcttcgtttc cttctggtca tctgattcct tctgatcttc cgactgttta gcaacaaatt
     1681 ctttttctga ttgttgtttt attttaggct ctaaaatttc attttccaat ccagaaactt
     1741 gtggggccaa atgagcttct tgccttatcg ttttattaga ttctgagatt tttctagata
     1801 ttcttgctaa ctctaggctt cttgtttgtt ttactttccc tgttggagaa actgcatgag
     1861 ccatttgttg ttttttttct gacaagcttt cttcttgtct tttttgttct ttttgatcta
     1921 tctgtttgtt taatggtaaa acatgtaata gtgactgagc atggagttct tggagtgaat
     1981 acgggtcatg ataactatac ataatcgtaa aatcacctgt ttgtttggtc aaataaccat
     2041 cctccaatgg tacttcattg attgtaaccg atacatcctt taacggtacg ggtttaccta
     2101 aggaatttgt tgctgattgg atcaactctt ctttgtttat tttttcgttt ggatgaacaa
     2161 taagatcatg accttctaat gaacgattgt ctggtatata aacataagta aaggtaattt
     2221 cccctcctga ttgcttccta ttattcatca gttctgagtg aagtacttca aggatctccg
     2281 accagtgact ttttctgtct aatccgtttg cttgcatcca atcagaaata gaagtgactt
     2341 tcccattttg ttcataagtc gataaatcta tatttggcac tcgatcagaa aattcagcag
     2401 gtaggcgcaa atcaggaata cgatttacac tactcatatg tgtttctgct tgaagttctt
     2461 tatttgtttg actatctata aaatgagtga tgacagtcga tgaagcagca gatgcttcta
     2521 cataaactac agctgttgtt tctgccacat ttgatgtttt cgagtctata taagttaata
     2581 caacgggata ttctcccgga gttgtagtat ctactgtccc gttcattttg atttcttctt
     2641 tatttcctga agttccatcg ctttttgtta catattcaac aagatcttta ggggcgtaac
     2701 tctctcctgt tcttaagtga agatcttttc ctttgatagc tgtttgatca gcacgaacat
     2761 ggatcacagc agatgcagtc attgttttta aagcaattgg atcaaaatag gacaaggaaa
     2821 tagtagatgt tcctgtatta gtcgtatcca cgatattccc attgtttgaa attactttgg
     2881 acatatctcc ttgtgttcca tctgcgttct tcagcctttc taccagatca gatatcgaaa
     2941 cttttgtccc tgccagaaca tcgattttct ttctttcaaa ctgtgaataa tctttttcat
     3001 atacataaga aacttgtgcg cttccaccgt cctttatatc tgtcaaagca tgattcaaaa
     3061 tatcagtgat ctgttttaac tgatcacctt ttgtaggatc agtcatatcg gaaaagatag
     3121 aaagcggcac actgcttccg gtttccgatg tccataatgt tttgttagga attaaccagt
     3181 agtggtttat cgttggagga taactgactt tattatagga agtcaatgca ggaagtagct
     3241 gttttccatt tgcatcagtg aaagtatgag taatagtgat aggggaatca gtggtctcag
     3301 aaacagaggt acgtacgacc ttgatggttt gtgtcgttgc ctgaacgggt acatgcatat
     3361 agacacctac agataaactg atcagcatcg tgcgcatcat aaacttaacg tagtgttttt
     3421 cagaacacga ccgttcctta tctaaacgac aagcgtgttt atttagttgt tttgaacgtc
     3481 tttttgaaca catttattct tagtcctccc tactcttgtc taaacatgaa gtagtaattt
     3541 tcataagatg atttcattat ataaataaaa tcaaaagaag atggactatt aggagagtat
     3601 tttttttgat tttttattgt ttcaagaaaa tcggaataat aacttatgta ctttttaatt
     3661 ttgttaagta atatatctag ttatatctag ttatatctag ttaccttttc tttgaaaaaa
     3721 acataaatca gctaataaat atgtgagaca aagctgccat ccataaatac tagctgattt
     3781 tttcagttaa atgtctattt ttttctctga tgatggtatt tccaaaatat tcccagtcat
     3841 ctggagtcgg tggatttttc caaattatct gttctttatt aaatttttca agtaaacaat
     3901 cagataaata aatattcgta cgagaagtga ttcgactctc aatcacaata ttgtaatttt
     3961 taaatccttt cacttgagaa ataatgtaat cggtataagc agatccttgc gaaaaatcaa
     4021 tacagacatg aatcggtgct tcaaaatatg ataccggaca aataccgacc aataaaaaga
     4081 gataatcata aaataagcga atcatgaaac gttcatcttt tcccaagaaa tagcgtttat
     4141 tctcttgtat gaccttttgg attgctgtac tgaatattgg atacgtctcg aagaaaaact
     4201 gtagctgctt tttagacgta aagctagtca tctcaaagtc gaatatccaa ttttttcgat
     4261 tgacatgcat catacccata cgaagttctt ttcgtatata tagtctttct tcttcagaga
     4321 tttcaatcga aaatggtaat tgatcaatca attccactga cattttttga ctaatcatgt
     4381 ggatatcatg aaaatgagct tccgcaagtc caaatgcgcc atctaattca aattcttctt
     4441 ccgtgatcaa aaacaacatg atataagaaa tctcatcaat gatctgctct ttagggatat
     4501 gaagaaaaga aatatgtgat aaatccttga tgatcttcat tccttctgag ctcttaaagt
     4561 attcatctga aaagaaacgt tttccgattg gttgattccc ataggccctc aacaaactaa
     4621 tagtggttag caaattgaat ttgattcgtt ttgttgcaga cagttttaaa ttgaacagat
     4681 attcaaaata ttgcacgata ctctttgctt cattcatgac gctttctcta aatggcatag
     4741 aaaaaccatt aaagaccccg aaatataccc caaataatac gttccgtatg tttatttctt
     4801 ccccaactaa tatgtttttc tttaacttta tttgatgctg ttcaagaaaa gagactaatt
     4861 ctcttctttt tacataggct cttgatatgc ttaaaaaatg attctctgca aatttttcga
     4921 tcgttacttt tgaatccacg atctccgtta acagtcgagc aatttttgat cgttgaaagt
     4981 agattcttct taaatttttg atatccgtca aattcagacg ttcgacatgg atctctgctt
     5041 cttctgaaat ttggatctct ggctttgttt tgaattcagt aaattcttta tttaattcta
     5101 tgatataatt tcttgtttta aatttagaca aacctaatgt ttcatataac ttaggcagca
     5161 ctacataatt ctttttctca aattctaaat atctagctag cagcagtttt tctctatctt
     5221 cctcttctat aaggtaatcc aacttcatat cctacacctc aaaaaatgcc tcataccaat
     5281 tacttgatat gcagatgaaa gttcatcttt tcacctatac tgattttatg atggattatg
     5341 cttgtttttt catcagttat tctcattttt tatctttttt ttgagaatat tgcaaaaaat
     5401 ggaaaaattt atgaggaaat attctatatt ttttgtttta ttgtgttaaa atgtacaaga
     5461 tttgcgccat ttgcgtaaac aaccacaaaa aagagcagga cggccaccgt cctgctcttt
     5521 tacttatttt aagttccatt acttattaat tggctaaact tctgcttgtt tctgatattg
     5581 cttgtttttc tccaatgatc cgcacttctg tttctaaaga cacatcaaat ttttctttga
     5641 ttacttcttg gatgtgcgca atcaattcaa tataatctgt cgctgtcgca tgatcgatat
     5701 tgacgatgaa tccagcatgt ttttcagaga cttgtgcacc gccccatttc aggccttgca
     5761 atcctgcttg ttggatcagc tgacctgtat agtgtcctac tgggcgctta aagacacttc
     5821 cgcatgaagg gtattctaat ggctgttttg attgacgcaa ttcggtcaac tcatccattc
     5881 ttgctttgat tgcttcataa tcccctgttt gcaaactgaa tcgagcttcc aatacgatag
     5941 cacgtaattc ttggacttta ctgtgacgat aagaaaatac catttcgtct tttgtcaaag
     6001 ttttcaatgt tccatcttca agcaaaagat ccacttcagc aaaaacatct ttgatctctc
     6061 cgccatacgc acctgcattc atataaaccg ctccaccgac acttcccggg atgccgcaag
     6121 caaattcaaa tccagtcaat gattctgcca aagctgcata agtcgtatca atcagtgagg
     6181 cacctgcttc cgcaatgacc atcgttcctt tgacatgaat ctgtttcatt tcagtcagca
     6241 tgatgactac accgcgaatc ccgccatctt gaacgatcag attgcttgca tttcctaata
     6301 ccatccaagg tatatcatgg attcggcaat aatcgatgat ttgctttact tcttcttgtt
     6361 ttttcgggaa tgcaaggaca tcagctggtc cacctgtttt cgtaaacgta tagttcatca
     6421 atggttcatc aaacaatata gtaatcgtgg ctaagctttc aactatttct tctttattca
     6481 ctgaggattt tcctttcttt tctcaaacgt cctcattatt ctatcacgct taatacaatc
     6541 ttgccagtct tgttcaaagt tgatgacggt agtgatcttt aagcacttcc tcacataatt
     6601 catgacttct tacaacttct ttttgtttaa gcaattctgt ttccgattta cctaaacgga
     6661 tctgagaaaa gaaggcctct accattggct caaacccgcg tttgactagc gtgtttgtcc
     6721 agtcgccaaa ttctttcact ttttttccat cagcatcttg aatgacaagc tgggtcagat
     6781 cgtttacttc ataagtacca tttttacttg ttacttgata tttttctata ttagcgccac
     6841 ttgctaaatc catcgttaaa atagccgttt gattttgtgt ttctaattgt aaaatggcat
     6901 attccaaaaa ttcctttgtt tctcttatct ggtattttgt tctcaaaatg ggtttatcta
     6961 ataaatacac agctgtatca ataagatgta aaaacaaatc ataaaggacg aactctgtcg
     7021 tttcttttgc cgctattcga tttttttgta ggtggatcaa ccgcttatct gggatacgtt
     7081 tcaattcttc taccatagga gcaaagcgcc ggttgaaacc gatcatcaaa attatttggt
     7141 tcttatcagc taattcttgc aattcacgaa cttcatttag atggacactc agtggtttgt
     7201 caatataaac atggatacca ttttctagac attttttggc taattcataa tgtacttttg
     7261 ttgctgcgtg gatcatacat gcttcgattt tttcttctaa aagctcatcg atcgtttcat
     7321 atagatgttg gaacccgtac tctttttgaa ttctttcttt tgtttcttta tttcttgttg
     7381 caaaataaaa atcaagtgtt ccttgttttt tcgcataagt tggtaaatat gctttttctg
     7441 cgatattccc tacaccgatt acaccaatct tcatctactt tcctcctgga tcatttagtt
     7501 actttcatct tacaccattt tttactaaaa tgaggtacaa tagtatcgca aaggtaagga
     7561 aattaattcg aaggagtgtg cttttattga aatttatctc ttggaacgta aacgggcttc
     7621 gtgccatcgt aaataaaaat tttttagaag tttttcatga gttagacgcc gattttttct
     7681 gtctgcagga aacgaaactc caagcaggac aaattgattt agatcttcca ggttattatc
     7741 aatattggaa ttacgcggaa cgaaaaggct attccggcac agcgattttt gctaaaaaac
     7801 cagcattgaa tgccacttac ggaatgggta tcgatatcca tgatacagaa ggccgtctga
     7861 ttactttgga atattccgat ttctttcttg taacctgtta cacgccaaat tctcaaagcg
     7921 aattaaaacg tttagattac cgattagaat gggaagaagc cttttataat tatttggaaa
     7981 atctaaaaaa acaaaaacca gtcatcgtgt gtggggatct aaatgtcgct catcaaaaga
     8041 ttgatttgaa aaactggaaa acgaatcaaa aaaatgctgg attcactcca gaagaaagag
     8101 cggctctttc tcgactgttg gataacgggt ttatcgatac attccgttat ttttatccaa
     8161 cccaggaagg tgtctactct tggtggaact accgattcaa ttcaaggaaa aacaatgctg
     8221 gttggcggat cgattacttt ttgacgagca aagatttaga gccaggacta gctgatgcaa
     8281 agatccatac ggacattatg ggcagtgatc attgtccagt agaattagat ttgaaataaa
     8341 gaggttgtga aaaagtcgtt tagtttcgag tattaagaaa aattttgtga aaatggcttt
     8401 ccacattttg cataaatttg gcataatacc gagaaactgg cttttgaaca ctgtttatcg
     8461 agagattgtg aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagttc
     8521 ctcatatttt tcgtttggtt gggcttatta ccgcagatac aagcttttga acaccgttta
     8581 ttaagaggtt gtgaaaaagc tgcactgcat caagtaataa gaacagccaa acaaaaatag
     8641 ttcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
     8701 ttattaagag gttgtgaaaa agctgcactg catcaagtaa taagaacagc caaacaaaaa
     8761 tagttcctca tatttttcgt ttggttggac ttattaccgc agatgcaagc ttttgaacac
     8821 cgtttattga gaagttgtga aatcagcgtc ctgacctgag tattagagaa acaaatggca
     8881 aaatagttcc tcatattttg ctattttttg agctaatacc gagggtcagc tgattgaaca
     8941 ccgtttagtg gagaagttgt gaaaaagtcg cctactttcg agtcgtaaga aatttttttg
     9001 aaaatggttc ctcacaactt tgcataaatt tgacttaata ccgagaagtc atgatcccca
     9061 tctaactcca aatcacaagg aatgagttca aaaactagct tttctcaaca aatattacat
     9121 aaaaaattct atgttttttg ttaaatttat ttgctttttt caaaagtatg ttacagtaat
     9181 ttcccaagga ggttttacag aaatgaattt tgttgccatg gattttgaaa ctgccaatca
     9241 tcagccttat agtgcttgtt ctcttgcgct agtcatggta aaaaatagcc agatcgttga
     9301 tgaattctat acattgatac agcctgagac tccttttttc tggcgaaatg tccaaattca
     9361 cggaatccat caagaagacg tacgcaatgc gccgaaattc ccagaagtct ggcaaactat
     9421 ccaaccatat tttcaaaaaa atcgtttagt cgttgcacat aatgctgctt ttgatacaaa
     9481 ggtcttagcg ggatgcttag attattatca tcttgaacag cctaattatc tttctttatg
     9541 tacagtgaaa agtagccgtc gcctgtttcc tgaatttcca aatcatcgat tgaacactgt
     9601 gtgcgaaaat ttgaacatcc aattagatca tcaccatgat gcattggaag atagtcgtgc
     9661 atgtgcggaa atcctgcttt atcaagaaaa aaaattcggg acagatccat tgaaaaaact
     9721 tgtgactata aagtaaaaga atacttatga aacacacaaa gaggtcgtga gcctgccgtt
     9781 tcactccgag tcacaaggag caatttcaaa aaatagcttc tcatgtttat taaatattgt
     9841 gactggtgac cgaggagctg gcaggagaac accgtttatt ggagaggttg tgaaaaagct
     9901 gttctgcatc aagtaataag aacagccaaa caaaaatagc ttctcatatt tttcatttgg
     9961 ttggacttat taccgcagat gcaagctttt ggacaccgtt taccaagagg ttgtgaaatc
    10021 agcgttttga cctgagtatt agagaaacaa acggcaaaat agttcctcat attttgccgt
    10081 tttttgagct aataccgaag gtcagctgat tgaacaccgt ttattcaaaa aaaatggact
    10141 gcgacacgac ttttgtcaca gtcccttcgt gtgtttttct gccttctcaa aaggatgaca
    10201 gtttctcact cttttcctat ttcttctatt caatcaaata actcatttta tatacatcta
    10261 aaaattcacc tagatctgtt cttgcccctc taggcatgac cgcttcgatt tggaagccca
    10321 tttttcggta aaggtgtacg gctctttcat tacgaacttg aacgtcaagc tccaatcgaa
    10381 aaagtacacc catttccttc gcccaactga tgatttcttc tagcataaga gtgcctagtc
    10441 ccattcccca atattcctgc agaatactga taccgacttc tcccacgtga gacaaacgaa
    10501 attgactgtc tgccttgaca gatgctgttc caataatcgt cccttcatag attgcaagca
    10561 gcaataaatt attattgctt tcgtatatat aatccaactc ttcttctaag gtttctggtg
    10621 gtaacaggag ttctgcttca tccaaaacta aaaattctgt ctccttatta acttgtccca
    10681 tcatcaaaag aatgtctttt gcatctcctg gcactgcttc ccgcaagatg atcccaactt
    10741 cttcactcat gattttcagc ccatttttct agaattcgct gtttgaaggt ttcactttgc
    10801 tccccgtatg agattagttt cacataccgc ttttctaaat ctgtatcact tttttctaaa
    10861 atcagttcca aataatcctc cggcagtgct tcttctaata gatttcccca ttcaacaacg
    10921 gaaagcccat caccttcaaa atattcatct aaccctaaat ctgctccgct agctgctacc
    10981 cgataaatat ccatatgata caacggaatc cgaccttgac tatattctct aataatcgtg
    11041 tatgtcggac ttttgatcat ttgcgttatc cctaatcctt gggcaattcc tttcgtcaac
    11101 gttgttttac ccgcacctag atcaccagtc aatatcagat tgtcacctgg cattgcggaa
    11161 tgaccaattg cctctgcgaa ttgttctgtc attgttaatc ctgatagttc gatcattttt
    11221 catcttctcc cgctcttctt tctttttgcc agtatatcgc gtaatgaagt ttttttaaag
    11281 aaaaaatgaa ctagtcaaga acagcagctg ctgtttttgg ctagttcgcg tgtatttgtt
    11341 aatcaatcaa tgtttgtgct gctgtgataa tcgataattt atatacatct tcttcatttg
    11401 ctccacgaga caaatcagaa accggtttgt tcaagccttg tagaattggt ccgattgctt
    11461 caaagttacc gaaacgctga gcaattttat agccgatatt tcctgactgc aattctggaa
    11521 atacaaagac tgttgcttga ccagctactt ctgaatctgg cgctttcagt tgtgcaactg
    11581 aaggaacata agaagcatca aattgcaatt cgccgtcgat catgtattgt ggcgctagtt
    11641 ttttagcgat tttagttgct tcaactactt tgtctacttc tggcgatttc gctgagcctt
    11701 ttgtcgagaa gctcatcatt gctacttttg gttcgatatc gaacaattct gctgtttttg
    11761 cagaatctac ggcgatttca gccaattctt gcgcagttgg attcacgttg atcgcacaat
    11821 ccgaaaagac atatttttct tgatctcttc cacgtaccat gatcatcgct ccgcttgtcc
    11881 gactgatgcc aggctttgtt ttgatgatct gaagtgctgg gcgaacagtg tcgccagtcg
    11941 aatggatcgc tccagagacc attccgtctg caatccccat atacgtaagc atcgtaccaa
    12001 agtaattcac atcttttaaa atcttttctg cttgttcttt ggatgccttt ccatttctac
    12061 gttcaacaaa agtatccacc atttcatccc acttatcgta attatcaggg ctgatgatcg
    12121 taaagctaga tgttttgatt cctctggcat gcgctgcatt tcttatttct tcttcgttcc
    12181 ctactaaaat gggttccaca agttcttctg ctttcaaccg ggcagctgcg cctaaaatac
    12241 gagcatcagt agcttccggg aaaacgattt tgatcccacg gcgaacaatt ttaaatctta
    12301 aactatcaaa caattccaca agatgacctc cagacgtttt tatatgtatt atcatacact
    12361 attccagaaa aaaagaacag tttattttat ctgtatcagt caaaaatgct ggaaaaatta
    12421 agtttttcac atacaaagcg aactgcacta taacaggaaa gcgctgtttt attacactgt
    12481 ttcaggcagt tgccaatcaa tcggttcttc tcctaacgca aggagcgcat cattcgtttt
    12541 cgagaagggt ttggaaccaa aaaagccacg acttgcagat aacggactgg gatgtggaga
    12601 tgttatgatg atatggcgac tcttatcgat cattttgatt ttttcttgtg ccggttttcc
    12661 ccacaagata aacacgattg gtttttcccg ttcatttaat ttttcaatga tcgtgtctgt
    12721 taatctttcc caacctttcc cgcgatgaga atacgcttgc ccttcccgaa cggtaagaac
    12781 ggtgttgagt aaaaggactc cctgtttagc ccatgacact agatttccat gttgaacagg
    12841 tgcgattcca agatcatcat aaagctcttt atagatattt cttaacgatg gcgggatctt
    12901 tacgccaggt tgcacagaaa aagataagcc atgagcttga ttttctccat gataaggatc
    12961 ttgtcctaaa atcaccactt taacttcttc ataaggagtc aattccaatg cttcatagat
    13021 atgatacata tctggatgga tcttttggga cgcatattct ttttttaaaa attctcttag
    13081 atgcagataa taatcttttg aaaattctga ggacaaaact tcttgccaac tgttatgaat
    13141 gatttctttc aaaaactcca cctcctaata aaaagaataa ctcacatttt cttcaatcac
    13201 aagggacaat cttcaccctc agcacttgat taatatggta aactaggaac aagaagcaga
    13261 aaggaacgat aatcattatg atcaaattaa ttgcatcaga tatggacggc acattattag
    13321 atgcccatat gagtgtttct cctgaaaatg ccgaggcgat acgttttgca aatgatgccg
    13381 gtgttgagtt catggtcgct actggtcgaa actatcaaga agctcgcgca gctttagatg
    13441 aggtaggaat cgattgtgcg atgatcactt tgaacggggc acaggtattt gataaagaag
    13501 gaaattcatt gtttaccgtg tcgattccaa ataatcaagc aatctctgtt ttagatattc
    13561 tagatgctaa cggtatttac tatgaagtag caaccaacga tggtctttat tctgaaaatc
    13621 aagcgaaacg aattgaaagt tttgcttcca tggtggctac ccatttacct caccttacgt
    13681 ataaaatggc gattgccatg gcctcagcta agctggagtt attgcacatc acatacgtgg
    13741 acagtattcg tgctattttg gaagaaaaga atctggaagt tttaaaaatt atttgttttc
    13801 atacagaagg gccagctgta ttaggtccag ttggaaagca gatttctctt ttaggcgatc
    13861 tagccgttac ttcctctggt caaaacaata tcgaagtgaa ccataaaaac gctcaaaaag
    13921 gaattgctgt tgcccatgtc gctcacgagc gtgggatttc tttagaagaa gtcatgacga
    13981 ttggcgataa cttcaatgat gtcagcatgc tgcaagtagc aggagtcagt ttcgcaatgg
    14041 gaaatgcaga aatcgaagta aaagattatg ccaaatatac aacggacaca aaccttgaat
    14101 ctggcgtagg aaaagccata ttgcgcgcga ttgcagaaga cttgtagttt tatctagaaa
    14161 agagggatat agatgtcaga atttttcatt caggaaaagc agcttggacg tgcaactcgg
    14221 acaattgtca aaaacgaaaa aggacattcc ctgtttttga tggttggtcg ctggggaaca
    14281 aagggcgatg cattgtctct ttatgccatg aatggcgatc tcgttgctca catcaagcag
    14341 ataagcctga cattcggtac gcgttttgag ctgtataaag agttcgaaaa ggtgggaacc
    14401 atgcagaaaa tattcaattg gcccggtgac ttttattata ttcgtagact tcactggaca
    14461 gtccaaggtg atatctataa tcatcaatat caaatccatc atttcaatca gcaaatcatg
    14521 aaaatggata aagcaacact tttttcagga gattactatg tattggatgt ctcaaatgat
    14581 gaagatgctc cagtttgtat ttgtattgct gcggttttag attactggct ctaccgtaaa
    14641 gacaaaagtc gcgataagcc tgtttcttac cgacttaact taagttaaaa agatgtacct
    14701 gaaatgcgga aatacgcatt tcaggtacat ctttttagat attcttttgc atatgatcat
    14761 aaagatgacc actgatcatc cgctgaccga caactttgaa gtcatggcgt tcgtataatt
    14821 ttttagcctt tggatttttt tcatccacac ttagaccgat gacggagcga ttagctttct
    14881 tcgccaattt aggtaatgct tctaataatc gcgaaccgat gccttgtcct ctaaaatctt
    14941 ctgatacact gatagagtcc aaataccatt cgttgggaaa cgtttcttta tcaatgaaca
    15001 aacgtgtaga cgcatctagc tgatatttct ctaagatagg taccagtggc tgatcgatga
    15061 ttgattcttc ttcatctgta taaccgtaag caactcctgc aactttaccg tctatttctt
    15121 ctacgatacc tcgtgaataa ctgtaacgat aatttggatc agtgattgct tcttctaaaa
    15181 tctctaaagt cttttgttcc cctgtctgct tcaaaaatgg cagttccata tcttttagaa
    15241 tcactaagat caatggggcg atttctggag catcttcttt tctcgcaaaa cgaatcatag
    15301 tttcctctcc ttttctccat tctaacatgc agaaaaagaa atcgcaaaat cgttatttta
    15361 aaaaatcttc aatcttttca gtaatgaaat aaccatgagt aacgattctt gccgcttcag
    15421 ttcggcagta agggcagacg actggcattt ctttatcatt atgttcgact acattattga
    15481 cttcttcgta tgcaaatttt tttccgcaat tagggcattt cattttttcc atgttatctc
    15541 aacttccttt catctttact ctcttagctt actcttatat tgtaaaaaag agaagcaata
    15601 tccttcttct atgcagatat ccatacctga cggtcctgtt ctccatctat taatcggact
    15661 ttataataag gacgttcatc tttgactaga agtgtccact ctttcacttt tgcttttttc
    15721 ccgtagtagc tgactgcttc cttcatcgct gcttgcggtt gtttgaactc ttccgttttt
    15781 tctatatcaa aaagatgttc tgcggccttt tccgtgtcat ttcgtacggt tgttttccca
    15841 gtggatggat tgactgctat gacttgtcct tcacaaaaaa actggtattc atatgttgca
    15901 ttcgtaggat tctccaaatc tttttcaact gcaaaatgaa tagcagatat gttatgttct
    15961 tttgtttcgt tttttacgat tgctgctgct tttttcaatg agatccgata ttcctggtca
    16021 ctaatatcat ccatgtgaaa agcggcattg agcagtcccg tcataccggt aatccctatt
    16081 acgatgaggg cagcaacacc aaacatcatt tttttcattc ttcattctcc tgtttctttt
    16141 ttttaaagaa tatcaagaaa tgaacgaatg aaaaatcgaa tgaaacgaaa aaaaagtgac
    16201 aattttgtta tctttattcg tgcagttcta atggcaatcc gtctggatca aagaaaaacg
    16261 tcattttttt tcctgtaaag gtatcttctc taatcggttc tgattcgatc cctaaggact
    16321 gcaattctgc aattgtttct tcaatatcgt ctactttgaa agcaagatga cgcaagccac
    16381 aagcttctgg atagtttggt cgttgtggcg cattagcaat tccaaaaatc tccaattcag
    16441 cacttcctag tttcagatct aatttatagt catctcgttc tttgcggtaa ttttctctga
    16501 ttacttcaaa tcctaattta ttaacataaa aatcacgtga tttctgataa tctgaaacaa
    16561 tgatggctat atgatggatc gttgtaaggt tcatatgagc actcctattc ttcgtttaag
    16621 ctcggatcta tattaatctc cagttccatt gtaaatgtgt cagattgaaa aaaatagctg
    16681 tttttccttt ttataagaaa aaaggcaaaa aaaacagaaa gtaggtcctc caagacactc
    16741 ttcctgttcc caatataata aatgaaagta agaaattata ttttcaagaa aacaaacaga
    16801 aaattatcat aacacaaatt atttataatt gaaagactag ttttttttca agaaaagcat
    16861 acaatagatt gtgttagtaa atacagaaca cactacattt agtgtcttaa ggagtcctca
    16921 tacatgaagt catattttca gtttttagct catcagctaa aaggctggcc gcaacaaaat
    16981 tattatcttt tctttttcag tcttggctgc caggtcatga ctcttgtcaa tagtcccatc
    17041 acttggctgt ccgttattac atttatcggt accacgcttg gtgtattgtg tattttatcc
    17101 atcaatgcgg caaaatcagt caacggtatt ttaggtattt tgtctgcgat ttgttttatt
    17161 atcgttgggt tttcagcaaa gaactattta agtatcggtg aacagattgc ttatatgatc
    17221 acattggata tccccgtatt gttaagtaaa gaatggaatc ataatatggc ttcaaaaatc
    17281 cgaaaattca ctggaaaaag ctggtttatc gcaatcatca gtactttcct tgtctatctt
    17341 gtttcaggat tcctgattgg tcgttataca gatgatcctc ggccgtgggt agatgccatt
    17401 gctttttcta ttagcttgac tgctggtatc atcagtttct tgcgttacaa caaccaatat
    17461 tactggtggt tagcttcagg gcttgctcaa atggtccttt ggtatatttc atttacgcat
    17521 ggatctgcaa gtttggcgat gttcgtgaac agctctgttt acttgctgaa tgatgtcctt
    17581 gcatttaccg tttcaccttg gtataaccaa aaagaacgtg aacgtatgca aaaaatggaa
    17641 gaagaatact acaacgcaca acaacacgca taaaaaaact gagcgtggga caaaagtaaa
    17701 gaacactttt gtctcacgct ctaaacacgt ataaacggcg gaatcagaag caactccttc
    17761 ggaaataagc tgaaattcac aaaaatttga aaagcaattt tcgtgaattt cttcttattt
    17821 cttggagtta aacgcttctg tcccagcctc tattttttat agtaattcct tcagatactt
    17881 tcttgcctca tcattgaaac gcagtgattc ttctaacttc tgataatatt ccaacgcttg
    17941 tttctgagct tcagtaaaac gataatgttt tcctttccat ttgtcgattg tctcttgcac
    18001 atttccagat tggatatctt tcactactag ttgccatttt tcttttgaga ctgtacggtc
    18061 tttcttatca gcagattgta tagcttctcg ttctttacgc aatactttta aaaaaccatt
    18121 tctgactatc cgaggaatgc tgtcgaagaa cccttctgta aaaccatagc gacaatattg
    18181 cttccaaata aatagataga tttttggttg gatgaatcgt tggtttttcg caaaatattc
    18241 catctgagca gtgacttctg gtgttcgttg acgttttgtc tttctcaaca cggaaataaa
    18301 tgtttcaaaa taagcattag gatgtactgg cacttcttca tatacgatgg attgccaatc
    18361 tttacgtaaa aatgcgcgat agttgatcaa gaattcttct acatccttta ctaattcttc
    18421 tgcaaagtcg tcaaatagtt ctttttttat ctgtcgcttt tttgactgcc cattgatgtg
    18481 ttcacttatt ttcttgattt cattttccaa tgcttgataa tccgctatgt aaatcggcat
    18541 ttctacttgg cgaaattctg cgagccgctg agctaatttt atatccggta aatatggctg
    18601 tttcatccga cgattttggt acaagacaaa acagtatttt tgccatagtc cttcaggaaa
    18661 atcgatattc ttctgcttaa gccataataa ttcgtctaag gccagatcaa cttttgtcat
    18721 tccctgatgg atcgaagctg ccactgtcgg agagacatgc aggtgatcgg caaagtggtt
    18781 gatgcctagt tttaggatct ttccggtttt tggcgattta acgatgtatt gcacttttaa
    18841 ttctctacca cactcacaat acaatttttg ctggcttcgt tttgttcgaa aaaacggatt
    18901 gatcttgaag tcagaaaaca cccaatctgt tgcagctaaa taatgttctt ccataaaacg
    18961 agagctgatt agatatcggc ggtgcttatc gactagttcc cgctgttttt tcgttaattt
    19021 tgcatagatc tcccaacgtt gactgcttgt gtattgttta gaaattttga tgggatagct
    19081 tttgctgatt tcttttggaa accattcttc aaagacggat tgccattctt ccacggctgt
    19141 ttctttcctt tctaattaca aaaagctggc tactaacata acgttagcaa ccagccagtg
    19201 tttcttgcta aattagtgag ttgttccggc atttccggaa atatcttctt tattttctac
    19261 tgctgcttca actgcataag tcaaagaaga agcaatgtct tctaaagaca tagaaggcgt
    19321 acccactgga cgatcgatca cttgatcggg tgagaatggc acgtggatga acccacctcg
    19381 aattgccggg aattgtgttt cgatcaaatg aagcaaacga tacatgatat cattgcagac
    19441 aaatgttcct gctgtataag agatgtacgc tggtagacca tgatcttgta cattttttgt
    19501 cattgctttg attggcaatg aggtaaagta agcggctgga ccgttttctt ctaaagccgt
    19561 atcgaatggc tgatttcctt cattatcagg gattcttgct tctgctagat tgattgcgac
    19621 acgttcgaac gagactgctg accgcccacc tgcttgtccg acacagatca cgacatctgg
    19681 ttggtgctgt tggatggctt ctttgactac ttgactgctt ttttcgaata cggtcggtac
    19741 ttccactttg atgatttcag caccgctgat ttcatctggc atttttttta ctgcttcata
    19801 ggctggattc actttgtccc caccaaatgg atcaaaacct gttactagta ctttcatctg
    19861 ttgttcctcc gtccgattga tttaacatat ggttatcttt tatcatacca ttttccttga
    19921 acagcgtaaa taaaggaaac aatagtttaa ataacataac aaatcaaact taatatattc
    19981 ttataaaaaa atagtgttcc actacaatgt tagaagaggt tgcgacaatt attctgtcac
    20041 aacccctctc ttctattatt taaatagaat catataagca atttggaaaa ctagcataaa
    20101 taacgcaata aacaactggt ttttgatcac tccgtatttg tctttcatct ccagcatcgc
    20161 tacaggcacg atattgaagt tagcagccat cggtgtcagc agggtcccac aaaaaccgca
    20221 agtcaatgca accattccta ttaacgctgg attcgctcca tgactaaata cgaatggtgc
    20281 accgatccca accgtcatca cggtgatggc cgcaaatgca ttccccatga ttaccgtaaa
    20341 tatcaccatg ccaagagcgt aaatgatgat gccgatgttc acatttcctt ctggaacgat
    20401 cgtacctact gcattggaaa tcactgtccc aactccagcg cttgtaaata ccgcacctag
    20461 agaagctaaa agcattggca acatgcttaa cggccctact gtgcccagca tatctgctgc
    20521 atcatctaaa aatgtacttg gtcgattatc tcgagaaaag aacatcaaga ttagcatggc
    20581 tgcaaaaaca ccgacgccca cgccgactaa agcacctaaa ttggtaaata gagcaaacaa
    20641 gatcgcaaag acaccgatac tcaaagctgg aataaaaatt ttcattccta gtttgtctga
    20701 cattttttcc atatattctt ttgatggaag ccggctttct cctttgctga ctttcttagc
    20761 aattgctggt atggtcatcg caaagatcaa gccaccgttc acgattgccg gaagccatct
    20821 tcctcctgca ataactaccc ctaagaccgt ccagaaaaag gctgacccat aacgatgagg
    20881 attggtttta tctgttaaat ttcttactcc agtgtaaatc aatacgagtc ccatcacgat
    20941 ataaaggatc tccagtaatt tatcgcctaa taaaatatca ggatttgtaa aaaagtccat
    21001 cttattgccc ctttcctgga taatatttct tcgctaattt cttttcttta agatagaagt
    21061 agacacttgc cacaactaaa gccgtgatag ccactggaac ttccactaaa gcaagctgtc
    21121 ccaatgttac gtcatatcct agatctttca gtgttgattg gactagcaac gcccctgctc
    21181 ctccgatgaa tagtacttgg ccaaagaacc agcagacatt ttccatagct gaagccatac
    21241 cttttagttc ttcttcatgc ttaggatgga cttctaaccc ttttgattcg atggtcccca
    21301 atgccatcgg taaaatgatt ggacgaacaa atccagcaac tccaccaaaa ctcacgttaa
    21361 aagccgcaaa gatcattcga aagatcccat aaatatctac aatcatacca gcagatactt
    21421 tcttgaatcg cttgatcaag gaagccgctg attctttcag accatttctt tcaagcgttc
    21481 ctgttgccaa cataatgatg ataaaaatcg ccatcccgcg attgtttaca aaacttgtac
    21541 ctaaaagttc taacattcct tgaatgccaa gaccgccagt caaagctgta acaactaaag
    21601 caaccattac gatcaatatc gagtctaatt taaatgcaaa cccgagaata acaatcaaga
    21661 cgcctaaaag gctaagataa ttttccatat attttcctcc ataaaatgac aatatttttt
    21721 taattataaa gcaaaacaca taaaaaatat agttgttttc tcacgaaata gacactattt
    21781 ttaaatattt ttcgttattt ttttatcaca aaaattatct tacttattgt aaggtaaagc
    21841 tttttttaat ttattgcccg ataatatata gaaataaggt ctagttactg ttttttttaa
    21901 atgattaata aataacaact tctttctatg aaattgcaaa gcattcatct tcttttccgc
    21961 taacgatata tccgtcagtg cttggtacac tttactaaaa agtatgagat tgccgatatc
    22021 tggataggtg tgctatacta cagaaaaaga tatacgatct gccaccgggt aggataaaga
    22081 ggatgatcat tccattaggt cttttaaggg atgattttcc tctttttgtg tattttttta
    22141 tagttaagga ggaatgtaag tatggcatgg atggaattaa tcatagcagg aattttggaa
    22201 gtattctggt caacgatgat gaaatggagt gatggttttt ctaaaatcaa ttattctttt
    22261 tacacagtga ttggcatgat tgctagtttt tactttttgt caaaggcaat caaaagtttg
    22321 ccgatgagtc tctcttatcc tatctggaca gggattggcg cagttggttc ggtcataatt
    22381 ggtgtggtct tgtttcatga taagctgaat ctttccactt ggttctttgt ggggatgcta
    22441 ctcatcagta tcattggcat caagattact agcggccact agacacttgg aataagtact
    22501 gatcagaaaa aataagcctt tttatttaat attcaatttt tttatgaaaa aataagaaat
    22561 aagtccaatg acctagcgac ttctccactc atcaggtgta tgcttgtact atctatagaa
    22621 aaggagtgaa tatttttgaa aagtctttcg gtccaagaat tatccaagaa ctttggtcac
    22681 aaacaagccc tcagcgatgt cagttttagc ttatcccctg gcaaaatcgt tggattagta
    22741 ggtcctaatg gcgctggaaa aacaacgatc atgaaagcta ttttaggact gatccattac
    22801 tcagatggaa caatctgtat tggtgaaaat gagatttctc cctctagtca taaagggttg
    22861 gaacaagtag gagcattgat cgaatacccg ggtatctatc cattcttaac aggctatgat
    22921 catctgaagt tattctctga aaccaacgat gtatctgcta tcgacactat cgtgaatcag
    22981 ctcaagatgg aaaagtacat tcacaaaaaa gcgaaatcct actcgttggg aatgaaacaa
    23041 aaattgggaa ttgctcttgc cttactgaac catccgtcta tcgttatttt agatgagccg
    23101 atgaacggtt tggatccaca agcaacaaga gatgtgcgaa aaatcattac cgacttggct
    23161 actcagggca cctctttctt gatctccagt cacttactca gcgagcttga aaaaatggtc
    23221 gatgagctga tcctgatcaa tcaaggaaag atcatcaaac aatgtacaat ggctgaattg
    23281 aaccaaacag cgcaagattt catcgttatc tctacaacaa atgatctagc tgctcgaacg
    23341 atcttgacag aagctggata tactttggaa gatcctgata aaatcaagct tttaaaagaa
    23401 aacgaagaat tattaggaac cgtgatccag ctattgtctg cacaaaatat ccatgtgaca
    23461 gacgtccagc atctgacgaa tgatttggaa tcttctctat tggaaattct ggattcagta
    23521 aagggggaag aagaaaaatg acattgcttg taaaacaaga attatttaaa ttgatcaaga
    23581 aaaagtcaac tgctgtttta tctgttctat tagttgtttt gctcatagga acagcacttc
    23641 tagccaaaaa atacacgacg atcattgatc cagttgaaat gactgctcag ctttttagtg
    23701 ccacatcttg gattgtcttt atcatgattg cagctgcaag cacgatcatt tcgatggaag
    23761 cacaatatgg tacattgaaa aatctccttt atcgaaagta ttctcgagga gaaatattag
    23821 taagcaaatg gatcacatta gttatttatt ctgtttattt atacctttta gctattattg
    23881 tcactgtgtt gatgaaactg attcttttcc cttcgatttc cttcacggag aaggtttcta
    23941 ctggtcaaac actgatccaa agcttgttca cttatacttt gggtagttat atcggtttat
    24001 ggctgatttt aagtttagtg ttgatgattg cttgctttat caatagttcc ggtgcatcca
    24061 tctcagcagg aatcgtcttt tattttgctt cgtcaatcat atctggtatc cttattgcac
    24121 tcatccaaaa atgggagtgg atcaaatgga atccgatcag tatgttgaat ctgcaaaacc
    24181 aaattggaaa cgaagagatc atgaagcaat tgactcatct ttctactaat caaatgctat
    24241 tcggtaattt agcttacatc gttttgttct tagcattagg atatctcgta tttaagcgaa
    24301 aaaatgtatg atgactcatc aaaaaagagg ctgtgaaaga gacgttcagc cttattgccg
    24361 attggctgtc tcttaaacac cgtttattct gaaaaaggag ctgtgacaac atttgtgtca
    24421 cagctccttt cctagtatgt ttttgaataa acgacaggct cacaacctct ctttatactt
    24481 cttttatact tctatacgtg aagcatccca gtggcaaata aaaccattgc aatcactccg
    24541 accatcgtca cacctataag taaaatctta tctaagtgga tatgttgtac aggctcgttt
    24601 tgctccttac gtgctttgag gtaaaaataa atgcctggca agaaaagaac aagaacaagc
    24661 attacttcat taaaggctac gactagcata gcccatactt gaaaggcact tgctaaaagc
    24721 cctactaaaa attggaccca ttctttccgc tgataagaaa gtttcatttg gtacaatcct
    24781 aagaaaagcc acgtgaagaa aatagctgct gtaccaagtg tgtaagcaaa gttataagca
    24841 ctatcagtga ataataatga aagtaaaaag acattcgtac ataacgtcgt caatacgata
    24901 gcataagttg gtgccccatt tttgttgagt tttccccatg ctttaggcaa aagtccgtct
    24961 tcagccatgt ttcccattgt ttcaatcggt aagatcgtcc atgagagcca aacaccaact
    25021 aaagaaatga tcaaaccgcc gttgatcacg actgctcccc atttaccaac catcatttca
    25081 aacacatagc ccatagcagg ctgcgccttg atcgtttgca gctgattcat cgtcattgtc
    25141 ccatatggaa gcatggaaac caagacgtaa ataataatca agccgaatat ccctagaatc
    25201 gttgctttcc caacatctga ttgttttttt gctcgtgaac ctacgacaga ggctccttca
    25261 ataccaacaa atacccaaag catcaccatg atgcaactca atacttgact ggaaaacggg
    25321 atcggctgtc cattcgcatt caatataatg tcgctagaaa agttatcaat gaattgttgg
    25381 atcgaaaacg tgctgatagc tactacaata aataaaaata atggcactaa tttacagaat
    25441 gtgacgatag cattgacgaa actagcattt tcgactcccc gattcactag ccatgcatat
    25501 ccccataaaa agactgtact catcacgatc gatgccagat tttgcccacc ttcaaatact
    25561 gggaagaaat atcctaatgc gctcatcaac aatgttgcaa aagctacgtt gcctaaccag
    25621 catgtgagcc agtaacccca accgctgata aaaccagcga aacggccaaa accttcttct
    25681 gcgtaactaa agatcccgcc ttttaaatct ggacgttttt tattgatatt attgatcgac
    25741 aaggagagca tcaacattgc tgttcctacg agtacccaac tgaaaatagc tgggccgcca
    25801 gccgatccgg agatgtccgt cataatacca aatacgccac ctccaatcgc tgaaccaatt
    25861 actaaggcag caagtggaat taaaccaatt ccttttttct gttgctctgt atccatgtaa
    25921 gcatcctcca aaataaaacc gcttttatca aaaagtataa caaacctttt ttatttttac
    25981 ttaattaata aaaactttaa tagaaatata attctaccgg cttttttctc attatacaag
    26041 caaagcgcct agtccctttc caaattacac caccaaaaaa cttaaaaaag atgctatact
    26101 aaaaggaaag aattggagga tgatccatga acattttata tatatcgatt tcaggaaata
    26161 cgcgtgcctt tgccaaacat ctagcagaat atgctgaaaa aatgcatgca gaagatcctg
    26221 tcaatcctga agttacttta aaagaaatcc atgaaaatag tgattttacg aaagaaacag
    26281 aaccattttt tactttcgtt cctacttatt tagacggcgg aaatggttta gataacggtg
    26341 atacagaaat cttgaccgaa acgatgcgtg aatatctgga acatgaagac aatcataaac
    26401 tttgtcttgg tgtagtcggt agcggaaata aaaacttcaa taatcagtat tgtctaacag
    26461 ccaaacaata tgcacaaaca tttggctttc ctttcttggc agattatgaa ttacggggaa
    26521 caccatctga tgtgacacga atttatcaga ttttagcaga aaacaataaa taataaaaaa
    26581 gaagaagctg aaaaatagat ttcagtttct tctttcgttt ctattgtttc tatcatatta
    26641 agctttgaca tccatcacag gtgcttttgc ttttgcttta cctgtttttt ccaagacaaa
    26701 gttttttaca cgatccatat tggttaccaa gacgatcatg gatgtttctt tgcctgctgc
    26761 tttgatcgct tctaagtcag cttctgctac aagcgtatca ggtgtcactt gctgcccttc
    26821 tgttactttc acatcaaatg gcgtaccgcc taagtcaact gtgttgattc ccatatgaag
    26881 caagatttct aaaccatttg gcgttgtgat cccaatagcg tgtttcgttg ggaagacaga
    26941 gctgactacc ccagtaactg gagaatagat atgtccgttt tctggttcta caaagtagcc
    27001 ttcacccatc atcttttgtg caaaaactgg atcacttgct ttatctaaag aaacaactgt
    27061 tccgtcagca actgatgaga ggatagtcac actttcagct gaagtttgag gtactacttt
    27121 ttcaggcact tcatttactg tggctgtttc agtcgctaat tcttcttttt ctaaacggtc
    27181 tttaggaata ccgaagaaga atgtagcaac gaagccacca gcataagctg ccaataatcc
    27241 aaggatgtag cctaaccatt taccgtcaga gatcaatggg atcaaagcgg ctcctgaagg
    27301 tccaatagcg atagccccga catttccgat cattccgatc actgccccgc cgatacctcc
    27361 accgatacaa gcagtaataa atgggcgtcc tagaggtaat gttactccgt aaatcaatgg
    27421 ttcgccgatt cctaggatcc cgactggtaa agctcctttg atcatttctg ttaattcttt
    27481 atcttttttg cagcgaatcc ataatgccaa tgctgcaccc acttgtcctg caccagccat
    27541 cgcaagaatt ggaagcaata gcgtacgacc agtttcatca atcatttgca catggattgg
    27601 agtcaaaatt tgatgcagtc cgaacataac catcggcaag aataatgtgc ctagaacgaa
    27661 gccggcaaat gctccaccaa cgccaagtac ccagttgatc ccaccgacca tgccatcaga
    27721 aatgaaacct gctaaaggca tgatgaagaa aatttcaatc agaccgatgg caatcaatga
    27781 aagagttggt gtaacgatga tatctaccgc atcaggtact actttatgca gttttttctc
    27841 aacgattgac aatagccaaa cagcgaagat gacacctagg atcccacctt gtccagctgc
    27901 aagagcttca ccagtaaata agtttttcag tggtgcttcc ggattcatcc ctgtcagcat
    27961 cacaacggcc ccgataactc caccaagagt tggtgttgca ccaaaaactt gtgcagcatt
    28021 gatacctgta tagataacta ggtagctaaa catcccgttt ttcaagatgt tcatcacatc
    28081 gatatattgt tgccatgttg ctgcatcaag tgttccggct gtgactaagt ttgctaaaac
    28141 tgcggcaatc cctgccacga tcccagtacc gacaaatgca ggaatcattg gcacaaagat
    28201 attagaaatg tcttttaata ccgatttgat tttagatggt ttttgtttcg atttttgtgc
    28261 cgctttcatt tcttgtgccc gttcgtttac acggtctttt ccagatgctg atgaatttgc
    28321 tgtagctgca cttacagaag aaagtttttc tcctaatttc acgcctgcca aatcaaccat
    28381 ttgctgtgct actttgttca ctttcccagg tccgatgatg acttgaagct gttcatcttc
    28441 tactacacca agcactcctg gaatcgcttt taattcagag acatttacaa gatcatcatt
    28501 gatgatcttc atacgcacac gagtcatgca gtggacaatg ctttctacat tgcccatgcc
    28561 gcctgcccct ttataaattt gttttgccag ttcttccaaa gtcagttcgt tttttgccat
    28621 ggtcttttcc ccctcataag gtccctttta caaatccgtt tgcttcagct aattttgctt
    28681 gagcttcctc tttatcacta tttgtcaaaa tcatgacgat agccagctta acattttgat
    28741 ctgcttcttc aaagtacttt tcagctgttt cgtaatcagc ttctgtcgct tgcatgatga
    28801 ttcgttttga gcgttcgatt agtttttcat ttgttggttt gacatcgacc atcaagttat
    28861 tgaatacttt acctatacca atcatactga tagtagaaat catattcaag ataagttttt
    28921 gtgctgttcc tgacttcaat cgagtagagc ctgtcaaaaa ttctggacct gcatcgactt
    28981 cgattgggaa atccgcgtgt ttactgattt cggcttgttt attgcaagaa atcgttcctg
    29041 tgacagcacc gatcgatttt gcgtaatcta atccaccgat cacatatggt gtacgaccgc
    29101 tagctgcgat accaataact atatcatttt ttgtcaaatt cagcttgatt agatcttctt
    29161 gccctagctc ataagaatct tcggcccctt cgacagctac agtcattgct tcttctccac
    29221 cagcaattag acctatgacc atttccggtt ctacaccgaa tgtcggtacg cattcagcag
    29281 catctaacac acctagtctt ccacttgttc cggctcccat ataaatcaga cgtccacctt
    29341 ttttaaagga ctcaatcgtg ttagcaatca ctggttcgat acttgtcagt tctttttcaa
    29401 ccgcagcggc cactttctga tcttctttgt tcattagttg aacggcttga gaaatactca
    29461 tctcatctaa tccaaaagtt tcttggtttc tgcgttccgt tgttaggttc tctaaattga
    29521 ttttgctcat ttttatcttc cttcttttct tataaattga tagttcatac cagctttgat
    29581 ttggttgatc aatggtagct cttctttgat aactttagct actacattca ctttttcatc
    29641 cgctggcaaa tcatatttgg ttaattggat ctcacccata tagcgcaaat acttttcgtt
    29701 atctaaagta atagaccctt tcatacgcgt agctgtattt cttgctggga taggcggaat
    29761 ctctcgaaaa cgtgcatctg cgcttcgtat gacatctctt gcatcgtctt gccgattcgt
    29821 atgcttccct aatatatatt cgtaaaattc ttcatctaca ggttccgtat ggagcaagac
    29881 tgtctgttct ttttggaaag aagcaaattg ctcctgaaca ttttctgaca gacctgcatc
    29941 tccgatgtaa acaatatccg tgttacttgc taatagatct agagcgcctg caagaggatg
    30001 gatccctcga tgttcttcca aagttggcaa tccttgatat agtgggcctc tcaactctgt
    30061 atctcctggt acaaaacctt ggacaaggag accttgaatt ttgagccatt gatttttttt
    30121 ctgataccat tctttgtcca gccctgtttc gggacgtgga taataattat gccaagcttc
    30181 aatctgtgag aaatcagctt ctgcttcttt caattcatcg atatctttag gcgtgatcgt
    30241 gctagcattc aaactgattt tcaattgatg tgaccagtcg gcaatctgct gattggaaat
    30301 atgataatcc attcttaaac ctgttacacc aattgctttc aaaggcgtta gatcttctaa
    30361 tgaaaaaccc gctcgttcca atgcctctcc tgaaatatcg accatcaatt ctagtttatt
    30421 ctttttcgct tcgcttccta gttcgatcaa tcgcttttga tatgccgaaa catcatcttc
    30481 tggtatatgc atggaagtga aaataccgac aaagccattg gatgccattt ggcggatata
    30541 ctgtttcttc tcttctgaca aagaatcgtt cataaatatt gaaaagccaa acatattatc
    30601 cctctttttc tgtatccgtc ttcatttcta tgactagagt atatatctaa agaaacaaaa
    30661 tttcaatact tttattaaaa taattaaatt tcatttctaa aggttgagtt tatattatca
    30721 aaagaattgt cataacctaa aaaaggcact gctaagcaaa agcagtgcct tgaaatattt
    30781 tatttaaata acacaaaaac ataattactc ataagaaacc aattctgtat tatctaccat
    30841 gaatgtaaag aacccctcat taggcatcgg atgaaaataa gcattgatca ctcttatcaa
    30901 ggcattatga caaactaaca gatagacatt ttcttcgtct tcgatgcatt ctttcaataa
    30961 aggaacgatc cgtgcataca catctaagac tgactcccca tttgggaatc gtacagcgaa
    31021 cgctaaacgt gctttttgaa agttctcatc tttgcttggc agtccatcat aatccccaaa
    31081 atccatttct accaatcgtt catcaacggt cagcggcaag ctgagacgat cagcaactgc
    31141 ttgtgctgta tctcttgctc gttgaagagg ggaatggatg attttcgtga ttggaacagg
    31201 caaatctact accttttctg ctagtttctg tgcctgcatc tgtccttttt cagtcagcgg
    31261 cacatctgcc cgtccgcaaa ctaatccttg tgcgttccaa gttgtttctc cgtgtctcgt
    31321 tacataaagc atgtgattct ctccttcgtt ggcaaatttc cccttaacca taccttgttg
    31381 ttcttgagat tacaagggtt agattctctc aagagaaata atctcagtag atactttatc
    31441 caggaaggtt tgatcatgtt ccactagtaa catggcaggt ttcacgttca agatcagttg
    31501 ttctaattgt tcttgattga agacatccaa ataattcaat ggttcatccc atgtatatag
    31561 ttcagctggc tgtgataaag atttagccaa ttccactttt ttccgttggc ccatactcat
    31621 ctgctcgatc ttgttatgaa aaacatctct ttccatccca agctttcgga ggttgttcaa
    31681 aaatgcttgg tagtctactt ggtttttctc tgcaaattcc gccaacgttc ctcgattgtc
    31741 ttcataattt tggcgtacat aactaatgct cagatgtttt ggctgggatt tttctcctat
    31801 aaccttgccg ttgaatgccc ccagaagata atggataatg gatgactttc ctgcaccgtt
    31861 aggacctgaa atcgccaccc gctgatgagg ctcgattgta aaatgaattg gctcgaataa
    31921 cagattttca taccctaatt gaagatcttc tacgcttaaa agtcgcttat ggtgagacgc
    31981 ttggctattc atcgtcaaag aatcgatata ttcgatatct tttaatagtt tttctttctc
    32041 gctgatctgg gtctccatcc gattcacgat tgctttggat cgtttcatcg tccgtgcagc
    32101 atcagcaccc actgctcctt tattcactcg tctagattca gtatcgatga atccgacttg
    32161 tttctttgtt ttatctcctt ctcgggaacg agaccattcg gctttttcag ctgctgtttt
    32221 ctttagccta ctgacttctt ttttcaattt ttcattttga gccatttcaa attcatcacg
    32281 aagttttttc tgttcttcat agatagagaa attcccttga taaagttcca gttgactttt
    32341 ttcgattgct aaaacatggt ccactacttc atcgataaat ccccggtcat ggctgaccac
    32401 gatgaagcct tgttttttct ttttcaaata agccgctact tgttttctac cagagatatc
    32461 caaatgattc gttggttcat cgattaacgg gaaatgagtg tcatccacaa ataaaagtgc
    32521 cagtaggact tttgtcttct ctccccccga tagtgtgctg aattctctcc ataagatttc
    32581 aggatctgtt tgcatcaatt ggagctctct ttcgatttcc catatctcaa aatccgtaat
    32641 atcatttaac acgtaatagg ttaaacgttc tttatctttt gtctgttgcg ggaaataggc
    32701 aaattcttgc tgatggatta cttgcccttg ataaggtagt ttgttttgta gaatattcag
    32761 taaagttgtc tttcctcgac cgtttcgtcc gataagtcct agtttccatt gtgtgtcaaa
    32821 atttagattt gcttgttcaa ataataatgt gccttggctg tcgtagccga atgtcagatt
    32881 ttttatttcg attttagaca ttttccatca cctcgtaaaa aaagaccagt cctattttca
    32941 gaactggcta aagaggatgc aagggttgga tacacacaaa aagacccata catcgaaaaa
    33001 accaagccaa tcccgaaaat ctgcacactg cttccttgtc tccacaaggt acagtctgaa
    33061 tgcagctttc atcaatcgac ttaatttttc aatgcacgga tccctcactt tgtcctatat
    33121 ttgaaattac gatagcataa agaaaatgat tttgtcaact acttcgggag gatggtgaaa
    33181 aatctgctaa gtgtctgtcc taagattttt gttttttcta atgtttgcct gtgttccatt
    33241 gcttcttcta aacctattgg acccaaatga atacttaaga caattgggag aaaatcagag
    33301 agtccttcta gctcttggtc tctacttccg caaatagcga ttattggttt tcgatatttt
    33361 tttgcaagca ctgctacacc gtgtggaact tttccgtgga tcgtttgctg atcgatccgc
    33421 ccttctcctg taatgatgac atctgcttgt tcgatctttt tttccaatcc agtgatttgg
    33481 ctgactaaat cgaaaccaga aaccatcttc gctcccaaca aaaaaagggc tccaccaata
    33541 ccgcctgctg ctccacttcc tggaatatca tctaaatcca cctcccagaa atcttttatt
    33601 tgctgagcaa tctttcctgc ttgtttatct aagaaagcta gcgtcgtatc tattcctcct
    33661 ttttgtcttc caaattgcca agcagctcct tgttgacctg tatatggatt ggtaacatct
    33721 gcagcgataa tcaattttac tttagaaaca agaacgtttc ttcgatcaaa atgaagtttt
    33781 ttagtagata ataaaggatt tccttctgtg tacccttcta aagaagcacc caaggattgg
    33841 agtaatccta gaccaccatc gctacacccg cttcctccta aagtgacaat aatttgttct
    33901 acttcttgaa gcagtgcatc tttgataagt tctcctaagg cataactgga agcaagtcgg
    33961 atagtttgat ccgttggttt atcaagtaga tctaacccca atgcttgtgc agattcgatg
    34021 actgcggtat tttttccttg ccaagttgtc aataaatagc tgatttttcg ctgacggaat
    34081 aaaagatcca tcccatcaat ggtacgccat gttcccccga gcgcgtaata gattgcttct
    34141 gcagtatttt ctccgccatc tgcaatcggc acattgattt ttcttccttt acgatcttcc
    34201 cagccattta gaactgcctg atttagttca aatgaagaag cacttccttt aaatgaatca
    34261 attgccgcca aaatatccat ctgtatccct cactttcttc ttaagtaaga cacttttttt
    34321 catttttttc aaacaaaaca atgctatttt cttccatttt tctatatact aaaagggaac
    34381 tcattgataa aggagagaaa aaacatgaaa atcgcaatag ctggagccgg agcaatgggc
    34441 agccgaatcg gattgatgct acatcaaagc ggaaatgagg tcctcttgat cgatcgttgg
    34501 cctgcacaca ttgaagccat tcgtacaaat gggttgattg ctgactttaa cggtaaagaa
    34561 gtggtcgcaa aactgccaat ctattcacca gaagaaatca tcgaaagcaa cgaacacgtg
    34621 gacttgatcg tagcattaac aaaagcgaat caattagatg atatgtttcg ttcgatccaa
    34681 tccattatta ctgacaatac ttatgttttg tgtttactaa atggattagg tcatgaagat
    34741 gtactggaaa aatatgtgcc aaagaaaaat atcttatttg ggatcacgat gtggacagct
    34801 ggtctagctg gtcccggaaa agtcacattg ttaggtgatg gagaaatcga actagagaac
    34861 ttggaaccag aaggcgaagc atttacaaaa aaagttgtgg aagtctttca agaagcaaaa
    34921 ttaaatccga tctatagcca taatgttcgt tattccattt ggcgaaaagc ttgtgtaaat
    34981 ggaacattga atggtttatg cacgattttg gattgtaata ttgctgaact aggcgcgcaa
    35041 aaaacggcag agagcatggt tcgaacaatc gtatctgaat ttgcttctat cgcagcaaaa
    35101 gaaggaatca tattagatca agaagaagtg taccaacata ttgcttctac ttataatcct
    35161 gacaacatcg ggttgcatta cccatctatg taccaagacc tgatcaaaaa ccatcgtttg
    35221 actgaaatcg actacatcaa tggtgccgtt tggcgaaaag gacaaaaata tgatattgct
    35281 acaccatatt gtgccttttt gacccaatta gtccatgcaa aagaaggaat ccttggcgca
    35341 gaataaaagg ctctctgatg agaatcagct gaatcagcag ctggttctct ttttttaagc
    35401 ccaatgaaag atcaaaaaga aaacacaact ctcatgatgc cataagaatt gtgcttgttt
    35461 gtttcggtac ataatctctt caaaatgtag gttttttatt tattttcaac agaggagagg
    35521 tcatattcgt attgctcata aatagtggaa tcgttagtga taaatcgttt tgcccaattt
    35581 tctgcatcat aaaattccaa tagctctgat gggattggct taaaaggtgt atgcagaaat
    35641 tccggtaatt catctaaatc acgttctcga agcaaaaaaa tattttcagg acgataaaaa
    35701 tgataatgag caatcgcttg attatccgtc actagtttct tttgaaaata catagattca
    35761 aatgtccgca aagtcactcc ttgctgaccc tcccgcaaca gttccagaat cccgcgcgat
    35821 tcccctgttt ttttcaggta ctcttcataa gcaagatatc caggttgttc attccctcga
    35881 tgtggaagaa tgaaatagtt ggtcgtaaca tctcttttta taaattcctg cttatagctt
    35941 tctgctcgtt cttttctccc attattcgtt gcaccaaaaa atagatccgt ctttggttcg
    36001 ctagaagaaa aatccatatg tttcgaataa aatgaactat tatgtttcag cccaagttct
    36061 tttgcttcca aaaaatcaaa atgataaatc tcatcgattg ccggttcatc ttgtgcctgc
    36121 ttcagcatcg cctcgtgttc tgctttgaag tgattccaaa aaaataacac aatttttgca
    36181 ttggtaaatg ggcgcacgcg tcgagccatc tccatattaa atccataatc taaaaaaacg
    36241 atcagctgat aatttgccaa ctgttgtcta gctgatttaa tgaattccga ctgtagtaaa
    36301 tcttttccgg accaaacatc taaagagcgg atggaaggca aaaaataaag tgatttattt
    36361 tttgcaacta gcagtacgtc atttttgttc atcttttccg cctcactttc tctgtcactt
    36421 tttcctatga tagcctgttt aaatagtaaa aagccagtaa aacgcttcct atatttgtat
    36481 gaaaatttaa catttgtatg aaaatatgat gaaataaatc attcttctat taaaattcgc
    36541 ctaaaagttt tctgaatagt tgtaattgtc tgaaaatttg ttatcattag tcattgttaa
    36601 atattgctat ttattcttaa tataaatttt gattgtgaat ttaaaagaaa gaggtcattt
    36661 atggaagata aaaaattgaa aaaacaactt agctccagac atatcaccat gttagcttta
    36721 ggtggagcaa tcggtgcagg tctatttaaa ggaagtggcg aagcgattgg gatcgccggc
    36781 ccttctgtat tgattgcttt tttgattggc gggctgattt tatatatcgt gatgaaaggt
    36841 ctgggaaaaa tcgttttaag cggtggcgac acgcatcacg gattatctgg tttgatacgc
    36901 ccttatctag gtgctcattc tgctgatttt actgattggg tctactggtc tatgtggatt
    36961 atcaatatca tcgctgaagc tgttgcagct gcttcctttt tgcagttgtg gttcccgcac
    37021 attccagcct gggtatttgt ttttatgttg gctgttttaa ctacgatcat caatctttat
    37081 tcggtacggt tattcgcaga aacagaatat tggctggctt ttgctaaaat cagtgtcatt
    37141 atcttactaa tcatttttgc tacttatctt gtcggtcagc aaatgttggg cacaggcgtt
    37201 ttccctaccc ttcagcaatt gactgaccat ggtgggttta ctcctcatgg tatgaaggga
    37261 atcatcagtt ctttgcttgt agttatctat tcttacggcg gttctgaact gattgctatc
    37321 acggtaagcg aagcagatga tcctaaacgt gcgattccta aagccatcaa aggtgtcatg
    37381 ggaagaatca tttcctttta catcattcct ttgtttttgc ttttgattct ttttccttgg
    37441 aatactttag caggcacgaa tgtcagtcct tttgtgattg tatttgaaaa aatgaatatc
    37501 ccatttgcag cggatatcgt caattttgtt attgtccttg ctttgttctc atctatcaat
    37561 tcgggtgtgt atgcatcttc aagaattttg ttcttccgtt tgaaggatcg aaaaggttcc
    37621 tctagaaaac tagctgtttt aaacaagcat caagtaccgc aacgtgctgt tttattttgt
    37681 accagtgttc tttatcttgg tgtagctctt tcttattttg tcggtgacaa attatttggc
    37741 tatctggcag gttccctttc gtatacagta ttattgatct ggatcattat cagtgcggca
    37801 tcctttgtac tggcactaag aaaaggaaca ttatgggata aaggaatcag cttttttgca
    37861 ttagctgtct taggattgat tttccttggt atcctgttca cgaactccat tggggtaact
    37921 gtattgactg gcctgcttta cctgttcatt tatttcagtt atcaaaaaaa gaatgatgcg
    37981 ttcgtattga cgaatgaatg aaatcgatag aaaattttat tttatttatg tggaatagat
    38041 ggaactattg aagaaaggag ttgtgacaaa agtcttgttg caactccttt ttccgaataa
    38101 acagtctcat gacctcttgg taaacggtgt tcaaaaaccc tctgtgcaaa ataattgatt
    38161 gttctccatg ctcatgacat gatagaagaa aggaatgaaa aaaaggagtt tgttttaaat
    38221 gaaaaagtat tggaagtttt tgttgatgat cggtgtttca acggtagtta tgtttggtat
    38281 gatgtacttg aatgtctatg cgctcgatca tatcttcttc agtcgtacac gagtattcat
    38341 ggcgttgatg atgggtgcag tcatggcagt catcatgctg ttgttcatgt ggaaaatgta
    38401 tgaaaacaaa aagataaatg ttatgatctt agccgctagt cttcttgttt ttgccggttc
    38461 cttgtttatg gtacgaagcc aaactactgt caacgacaca gcttggatga aggccatgat
    38521 tcctcatcat tctatcgcta tcctgacaag taaacgagct gatttaaaag atcctgaagt
    38581 aaaaaaatta gcggaagaaa tcatccaggc acaagaagaa gagatcgaca aaatgaaaaa
    38641 aatgatcaaa gaaatggaat gaccattatc cgtccaaata aaaaaagagg atgttccaga
    38701 agtgatcagc ttcaagaaat aagaagaagc tacttctgga acaccgtgaa taaggggttg
    38761 tgaaaaagct gccctgcatc aagtaataag aacagccaaa caaaaatagc ttctcctatt
    38821 tttcgtttgg ttaggcttat taccgcagat gcaagctttt gaacaccgtt tattcgtaaa
    38881 agggattgtg acaaaaaaag tcttgtcaca atcccttttt atgtttttat tgttctaatt
    38941 gcgctgtctt gcttactgct tcttgcggtt tcacaaattt ttttgagatt ccccaacctg
    39001 tgaaggcact gaccatcgaa aacacaggag aaagcaaact gaaaaatacg aatggcaagt
    39061 aagtgagtgt aggaatacca aatgtacttg ctacgaaact tccggcaatt ccccaaggca
    39121 ctaagtagtt gattactgtt ccaccatctt ctagcgttct acctaataca gttggatcaa
    39181 atcctgcttt ttcataagtt tctttaaatg cattaccagg cagaataaca gataggaatt
    39241 gttcaccaat aaaaatattt actccgatac ttgtcatcaa tgttgtaaaa atcaattttg
    39301 gtgtgttcgt catctttctt gatactcgtt ccatcacggt tgagatcaag ccaaattcga
    39361 tcaacaatcc acctaatgac aaagttagaa taatcaatga cacagtaggc atcatacttt
    39421 cgattcctcc gcgactaagc agtgaatcga tttgttggtt tccagtattt gaaacaaacc
    39481 ctgattcgat gaccccagcc aacttcgtta aggaagtttg tgggttttga ataaaaatca
    39541 ttcctactgc tacagcgata ttcaacaaaa tcgtcaaaat tgccggcacc tttttccatg
    39601 cacacagtaa cattaaaaat aaaggaatca gtgaccagat tgaaatagta aagtttgctt
    39661 ctagaacatc agtcacttca cgaatagatg aaagacttgc ggctttactt gtgtgtccta
    39721 aaatcatgaa taaaaagaaa gaaacaacaa atgccggaac agttgaccac atcatatgct
    39781 tgatgtgttt gaacaaatcg gcatcaacaa tagctgctgc tagatttgtt gattcggata
    39841 atggagacat cttatctcca aaaacggcac ctgaaacaat agctccaaca accagcgctg
    39901 gatttaggcc tagtgttgtc ccaataccga aaaatgcaat cccaatcgtt gacataacag
    39961 taaaggcact ccctacagcg ctacctacga ttgcacacac aacaaataca gaagggacaa
    40021 accactggac actgatcaat ttgaacccaa tgaccattag agttggaatg atccctgctt
    40081 gtatccatac agcaatcaat gaacctacta aaataaaaat aaagattggg atgattcctg
    40141 gtttgatgcc attgatgatt ccttcgtgca gccaatctgt cgggtatctt tttatcactg
    40201 catacaacat gaccattccg atcgctgcta agatcgtgat attaggtgag acctttaatc
    40261 cgacaacgcc aatcgcaatg cctaaaacaa taaccattaa tacaagtgtt gcttctaaaa
    40321 aacttggtgt tccttttttt cccatgataa tctctccttt tttagttgtt cttatgttct
    40381 aaaaaagtta agatatcgga ttactccgcc gcaattcatc cgctattcct cctttataaa
    40441 aataaaaaga cctgttttaa actaaggacg aatgactccg cggtaccacc ttaattaaaa
    40501 acagatctgt ttttcacttt caaactttta ttcaaatgta tggactttcc atgtaattcg
    40561 tcaattaggc ttgatcggtt cacagcgacc accgactttc tgaacaaaac acctaaccgc
    40621 tactgcgtga aaagttgact tgtatgaagt ttaccttcca taagatcatt tgtcaatgaa
    40681 aaagaaaata ttttttcatt tttctgaaaa ttatttttat aactttcaca cacaagttta
    40741 ttttttacta gaaagtagca ccctcttgtt tttttcttgc tactatttct tgatgttctt
    40801 gcttgattct ttctaatagc tttggctctt tcaacagatc aagagctgta ttggcgagta
    40861 gttctgctgc aatcgcaata gaagcaaggc ctttgtcact tttagcagca gctttgaatt
    40921 cttctgtgtg tccggcaata tatgtctcag agattgctac cgtaggctgg attgttggta
    40981 tgacttggct gacatttcct acatcagaag aaccgagact tgttctttgt tccgtttcta
    41041 tttcttcatc tggaacacct gcttcttttg catgctggaa gaataagtca tcaaaagaag
    41101 gagtaacgat gacatcatca actgcatttt ggaacaatcc aaactcaaaa gtcgtgcccg
    41161 tacttatcgc agcacctcgt acgatatttt ccactttttc atatacttta tctaatgttt
    41221 gccgatttcc tgcacgtaaa tagaaacgtc cagcagcgta atctggaatg acgttggcag
    41281 ctactcctcc gtctgtaatg atcccatgga tattgacatc ttttggcaat tgcaagcgta
    41341 gagcgttgat tccattaaac acttggatca atgcttccaa agcatttact cctttttcag
    41401 gtgctgctgc tgcatgggaa gcgacaccgt aaaatttgat gtcgactgga tcattcgcta
    41461 aagattctgt cgttttccca taacgaaaag ctggatggac gcataacgct acatcgacat
    41521 cctcaaaaaa accttctcga acaaagctgc ctttagctga tccgttctcg cccccttctt
    41581 cccctggggt gccatataca cggatttctc caccagtttc atcaataaat tgctccacta
    41641 tgctggcggc taatacggag taagtaccaa acaaattatg cccgcatgca tgaccaatac
    41701 ctggtaaagc atcgaattct gccaaaaagg caattgtggg tccgggttta ttggaaatat
    41761 aacgtgcatc aaaggctgtt cggtgtccag ctacttcttt ttctacccaa aacccttctt
    41821 tttctaattg tttaatcaac gctgctgagg aataaaactc atagttactt acttcaggat
    41881 gttcgtggat atctagagca agtgcttgat attctggtaa acgatattgg attagatcct
    41941 tcaattggtt tgttgagatt gttgttgtca taaaaaattc ctcctatgct agtcattttt
    42001 cttattttct cccgaatgtt tcccatgcag gcacgcttga tccttttgat gttttctcga
    42061 ttactttgac tgtgtcttct gtttgataag cgtctactat tttttgatac gttttatttt
    42121 tttcatcttc ttttcttgca acgatgatat tcacataagg acgtgcatgg tcatccactg
    42181 gttctaagaa gatggcatca gaagcaggat taaatccagc atctacagct acaccgctat
    42241 tgatcactga aatgtctaca tctgacaaag cacgtgctgt ttgggaagca tctaattcag
    42301 aaatgtctag attttttcta ttctcggtaa tatcagaaac agtgggcgct tgtccttttg
    42361 ccttatccac tttgatcaat ccagcagttt gcaataacag aagagctctg ccgccatttg
    42421 taacatcatt agggattgct acttttgctc cgtctttgat atcagctaca tccttcaaag
    42481 tgttagaata aattcccagc ggtgcattga cagtatttcc gatcgatact aaatcagttc
    42541 cgtgttcttt attgtaattg tctaaaaaga attgatgttg gaaagaattc aaatcaatcg
    42601 atccatctgc taaagccgca tttggttgat tgtaatctgt aaatttcacg tattccaaat
    42661 taatgttctc ctttttcaaa cggtctttca cgttgtccca tacatctgta tcttctccaa
    42721 taattcctag ttttacggta gtttcttttt tgtcagttgt atctgctttt ccttggctac
    42781 accctgccaa ccaaataatt gctacaaatg taatgactac aaaacgaata atttttttca
    42841 ttttttctcc tccactttca atgtgtaatt tttttaatca gttgattact gataaattga
    42901 cttaaaaaaa ctaagattag aatcaataat gtagccacaa tcgttacatc tgtttggaat
    42961 cgattatacc ctctcgatat agcaagattc cctaatccgc ctgcacctac tgctccagcc
    43021 atggtagtca gtccgatcac gttgatgata gtcaacgccg agacccgaat gataccaggc
    43081 aaaccttcta acaaatacac acgtaaaata ataccgattg gactggttcc catcgcttct
    43141 gccgcttcga tcaccccagg atcaacttct agcagtgcgt tctcgatttg acgagcaaaa
    43201 aacggaacaa ctccaaaaat caatggcact aaagctgctt tcgcaccaat cgtcgttcca
    43261 actaagaaac gagtagtcaa tgctaaaaga gaaagcaaga taatgaaagg gatggaacga
    43321 atgatattga tcagcttatc aagtatttca aatagcagac ggttagctag taatccatta
    43381 gggcgtgtca ctactaacgt cacacctaag atgattccga tcatcccgcc aatgaatgct
    43441 gtccaaaaag acatatatag tgtttgcttc gtcgcttcga caaattcatc cggaatcaaa
    43501 taaacattgg gcaaatatgt tttaaagaaa tcagtcattt tatcttcctc cttcgatcac
    43561 tttgatacga ctatctaatt cgtttttttg taaaatattt atttttacac cagatttgat
    43621 caaataatcc aatgcttttt gccgctgttt ggtttctcca gctaaagtaa cgatcaaact
    43681 ccctaacggc gtttcttgta ataactctac attgccatat aaaatattcg ctgttacttg
    43741 atatttgctg tacagatgag cgattagagg ttcgttcgtc tgatttccaa tataacttaa
    43801 ttccaccagc catttattgg cgatctgatc ggcaaaagca gaatgggcaa tgatcgtttc
    43861 taatgcttgg tcaagatgag tagctgttcg aataaaatct ttggtcaatt cttcttcagg
    43921 attgctgaag atctggatgc tactaccttt ttcaatgatt cttccatctt ccataaccgc
    43981 taccttgttg cagatttctt tgacaacttg catctcatga gtgatcagga cgattgttaa
    44041 acctaactgg cgattcaatt tttttaacaa tgcaaggatc tgaagggtcg ttttcggatc
    44101 aagtgcactg gttgcttcat cacataataa taccttaggt tcattcgcca aagctcgtgc
    44161 gattgctact cgttgttttt gtccccccga cagttgttta ggataagcag atgctttttc
    44221 ttccaaaccg acaagttcca gtagttcatt cactttttga cgacgttcct gtttcgattt
    44281 tccagaatac tttaaagaaa aatcaacgtt gtcaaaaata gttcggcttt ccattagatt
    44341 gaaatgctga aagatcatac cgatggcctt tctttctttt cgcaattctt tgggagagag
    44401 ctgactcaaa ttcgtctgat tgacaatgac ttctcctgct gttggtttct gcagcaaatt
    44461 catcacacga actaacgtac ttttccctgc acctgagtaa ccgacgattc cataaacatc
    44521 gcctttttca atcgttaaat ctacagaatc tactgcctgt atctcttttt ctttttgttt
    44581 gaaacataca gaaacatctc gcaattcaat cattaaaatt cctccttatc taaaaaaagc
    44641 gtcctcaaga aaatgaaaat gtcattttct tgaggacgct tttttgcgtg ttaccacctc
    44701 atgttcaagc tgtgttcaca cacaactcct cttcaagtac gatcatactc tagcaagata
    44761 tcggtcgcag ccgtcatcgc cttacatcta tgctcgggat gaattgctcg atggccattt
    44821 tccaatagtc gttccttgct tcttctcagc taccgaagct ctctgtcaaa ggttcttcta
    44881 tcgtacttac catttcaatg caaataatat tcaaaaaaaa atccttttac taacataaac
    44941 tatgtcagta aaaggacgac gtatcgcggt accacctttt ttcggaagtt tccttccctc
    45001 aagcccaaca tctcaaaaag agagattggc gttcgtttta acggtcgaac agttccgaat
    45061 ttgcctactt atcgacaaat tattctccaa ggccattttc agcttttctt acttgactct
    45121 tctcaccagc cagagcctct ctgcaaagtt tccaaactta ctttcctttt caacgaaatc
    45181 gatattttgt tgttgggatt aatctacatg aggaaaacta aaaagtcaag cacgaaattc
    45241 aaattatttt ttctatattt atttttctgt ttttttatct aacatttcaa taacagttcg
    45301 aagatctttt ccttcagcaa gaagtttcaa tttttccttt tcttcgacgg tataatttcg
    45361 gacaaaactg gaatcaggta tcaaaacaac gcctaatcct gctcgtgaag cagctgttgc
    45421 tcctactaaa gaatcttcca ctgcaaaggc tgaactagct tctaatcctg ttcgttccaa
    45481 agctgtcaga taaggaatcg gtgaaggctt gttctccgac acttcgtctc cgaatgtaaa
    45541 cgtgtcaaag taatcagcta atttaaagtg atccaagata tctgttgctc ttttcgtaac
    45601 agtggtcgta gcaatgccta gtttcatatg acgttctttt aagtctgcca atatttcttt
    45661 tgcatatggt tttaagtgga tggctccgct tgtcagctgt tgataaaaat attcttcacg
    45721 cttcgctcgg acttcctgta ctttttcagg gctacctgct gctttcacta aaatatcaaa
    45781 actttgtttc cagttttttc cgccccaagc gtcaacgatt tcttttggga tatggatatc
    45841 aaattgctga aatccccaaa gccagccatc acgatacgtt ttttctgtgt caactaacaa
    45901 accatctaaa tcaaatattg cacctttcat ctatacatta atcctttcca aaacaataca
    45961 catagtttag cacgactggt ccaaaaataa cagaagcaaa gaaccagcct tctcgtttat
    46021 aagagttctt ggaatcgatg gatatagatt ttcttcacag ctgtcacaag cgccagataa
    46081 gcgatgactg tagcaaataa ccataaccag taattgccag gaagtggcat caagcctaat
    46141 tcagcaccaa aacttgtaaa aggaaggaca gaaccgacaa taattcctaa tgtagtgata
    46201 acaaacatgg caaatgttac gttgctttgg ataaatggta ctttcggtgt acgcagtgca
    46261 tggagcacta aggtttgtgt ccatagtgat tcgacaaacc atcctgcatg gaataatgcg
    46321 atgaaaatca cttgctgtga actatccaat gtatggaaac ttccgccaac tacagcagga
    46381 caaataacaa aatacatcaa caagtaagta gtaatatcaa atatcgaact tgttgggcca
    46441 aagtaaacca tgaatttccc aatactagat gcattccatt tttttggctc gtccaaatat
    46501 tctttatcca tccgatccca tggcaaggaa atgcaggaaa catcatagat tagattcaaa
    46561 aacagaagtt gtaaaggcag cattggtaaa aatggcagga acatacttgc aatcagcacg
    46621 gaaaacatat tgccaaaatt agaacttgct gtagccttga tatatttcat gatattccca
    46681 aaagtttctc gtccagaaag aaggcctctt tccaaaatcg tcaaatcttt ttctaaaagg
    46741 atcacgtctg cagattcttt cgcaatatcc acagctgtat ctacagaaat accgatatca
    46801 gccactttca ttgcaggagc gtcattgata ccatctccta aaaatccgac agtatgacca
    46861 tttttacgta aagctgtcgt caaacgtgct ttttgctgag gattcaattt tacgaatact
    46921 tcatggtctt cagctacttg tgctaattca tgatcactca tttccgagat tttctcaccg
    46981 gtaaccaatt cattgatctc tagacctact tgacggcaca ctgaacgtgt aactaattcg
    47041 ttgtccccag tcagaacttt tacagctaca ccatgttctt tcagagcttt caacgcttgt
    47101 ttcgttgttt cttttggtgg atcaaggaaa gtaagataac caatcaaaac catgtctgac
    47161 tcatctttga ctgaaaattc tccaacgacg cttggattgg tcttttgtgc gacaccaatc
    47221 actcgtaagc catcttcatt aagtgactgt acttttgcaa gtacggcttc ttttcgttct
    47281 tttgttaatg gtgtaacagt accgccaaga tcaataaatt tagaaatgtt cagcatttct
    47341 tcaatcgcgc cttttgtgat catttgtgtt ttaccagctg gatcagcaac cacaacactc
    47401 atacgacgac gttcaaaatc aaaaggaatt tcatccactt tttgataatt gatcttatct
    47461 gtatctaaag tttctgttgc ttcatcaatg atagccacat ctaacaaatt tttcagccct
    47521 gtttgatagt agctatttag atacgcatgg cgcaaaacac gatcatcttc atttccttca
    47581 caatccatat gatattcaag aatgatttta tcttgtgtca atgtccccgt tttatccgtg
    47641 cataacacat cgattgcacc aaagttttgg atggcattca aatttttgat cactgttcct
    47701 tttttggcca tcacacttgc tcctttgacc aaattcgtcg taacgatcat tggaagcatt
    47761 tcaggtgtta gaccaactgc tacagatagt ccaaaaagaa aagcttctag ccaatcccct
    47821 tttgtaagcc cattgatgac gataactgct ggagccatca atgacataaa tttgatcagt
    47881 agcatggatg ttttatggat gcctaattca aagcttgatt gaattggttt ttcagatagc
    47941 gtttctgcta catgaccaaa tagtgtttca tttccaacag aaacaatgat tccttccgca
    48001 cttccactta tgacattact tcccataaag acaagatttt cgtaacttgt ttcgctttgc
    48061 tgatcgtctt cacatacttt cgcatgcttt tctactggat agctttcccc tgtcaatgct
    48121 gcttgggaaa tgaataaatc ctttgcggac aataaacgca tatccgctgg tatcatatcc
    48181 cctgctgaaa gccgaacaag atctccacag acgatttctt ccataggaat ctctgtgtac
    48241 tttccattac gttttacagc tgccgttact ttcacaagtg atttcagttt ttcagccgct
    48301 tgattggaac gtacggactg aatcaacgtc attgtcccgc tgacgatgac catagtgaag
    48361 ataatggcta caccgaaaag atctttatct ccaggagctg ctaatacata ttccgtgatg
    48421 aatgaaataa ttcctaatgc gatcaacact aatgtaaatg gcgtgatgta tgctttcaat
    48481 atttctacga tgaatggtgt ttttttgcca tatgaaatcg cattttcacc gtaattttct
    48541 cttgaacgtt cgatttgttc ttctgtcaat ccatttgctg atgcgtggaa tagttcaaat
    48601 aattcttgtt tcgtttttcc agcaaaagct gcatagattt tttgtgtatc tttctttttt
    48661 tccatctcaa tctctccttt gtgtccaaaa gacagctgtt ctcgctgctt ttggtcttta
    48721 gctattcatc ggatcgatag agaaaaaact gaaaggggct gagaacagat agataatagc
    48781 cttggccttt cctctagatc cttgtttttc gaatgactgt catccatttg ttctcatctc
    48841 ctttactaag taattttaat tcatgacttc caatcatttt tcgaatagtt attttcccaa
    48901 ttagaccacc tcctttttat ttttcaccga tggggatttg cggcaacaaa aaaacctctc
    48961 gccaaatact cagcgaaagg tttgaaaaag catattaaaa aaagcttctc agatctcatc
    49021 gttgagtttt gacactgtac aacgtaaaaa gcagatacct gcttttagct accttatgaa
    49081 aagccttatc tcgacaattc ctgttctacc cattggcgtc tctcgacgtt tttgggcagt
    49141 agcctatgtt tgtataggag cctcacctaa caaatcttat tcggttttcc ttcgttaata
    49201 taacaactaa aaaagaggat gtcaaatcaa ttttccatgt ttttcatact ttttttaaaa
    49261 tacacacgtt atattcctgt ctcacgcggt tttatttgtc tcattttcca cctcccgcta
    49321 taatagaaat atagtaggaa acgaggtgct gttatggaaa gaacacttgt tattatcaag
    49381 ccagacggcg tgagacgcca tttagtcgga agcatcattc aacgttttga agcaaaggga
    49441 ctggccattg ctgaaatgaa gtttgaaact atgactcctg aattagcaaa agaacattat
    49501 cagcacttga ctgagcgcag tttttttgat gaactgatcg attacatgac ttccggtcct
    49561 gtcgtttatc ttgtgctggt cggcgaggaa gtgatcgata tcgtccgtaa gatggttggg
    49621 gcaacaaaag ctgtcgatgc tgttccaggt acgatccgag gagactacgc gctgccgggg
    49681 actgaaaaca tcattcacgc ttctgattcc cgtgatgctg cggtaaaaga gatcgcccgc
    49741 tttttcccgc cattcgatat aaacaaaccg tctgaaaaag cggcgaagtg atacaaattc
    49801 taaactgctg gtctagttgc tgggttcagc aatggccagc agttttttct ctaaggacct
    49861 ccgttgattc tttcctaaca tatattcgag cactgtgaag aattcttggt agtctttcgt
    49921 ctttttttcc cctaaagcag cagaaatcaa tctttgataa taatctgcca tcaatgtttc
    49981 atagatcact gtacttcttt ctttatgtgc taagctccgt ttcatatctt cattcacact
    50041 acgtgccttt ttcaaccgac cattttctat ataaaacgaa gtcaggttca ttaaaaaagt
    50101 aaagagatac tgctcatgat tgttcaactg tgctaatcgt cgcattcttt ttttgatttt
    50161 caaataattg ttctcaatga accgatcact gaatatccaa ggaaaatcag ctagaataga
    50221 tagttcaaat tgaccatagt ctggtatctg catcaagtat tcttcaatga ttcggcattc
    50281 ataacgtaaa aattcaaatt ctgtctcaga tacttctgtt ttttcgacca tgtgaagact
    50341 caaaaccaaa taatacagat cttctgtttt cttaaaatgc ctacggttat tgctgatctc
    50401 tttataagga tcaaagctgt cttcttgtac ccgatctagc attcgtcttt ttttctttaa
    50461 ctttattggt tcatccagct ggtttcgcat ccattcatat tctgcaagtg tcatgttcat
    50521 tcgctctaaa aatgatctca atgttacaaa tgacattttt ttcactgaat ttgtctcaat
    50581 cccgactaga gaagtcttag aacagattcc ttccgctaat tgggactgtg tcaacttctt
    50641 gttgactcga agtttcttga tcaattcacc atcatacata atagttctcc tttttaattt
    50701 aaatttttcc acattcaata aatagatacg ttaaaaagga aaaatacacg aaaaaaataa
    50761 aaaaatgttt ttttcataaa aaataccaac cttcaagcat tagaatgttg tctaactact
    50821 gaaggttggt ttgattgttt attgattatc tttttgctgt tcaacgtctg ttcttgttac
    50881 tggatataag ttggttgttg ttttattgcc attttttgaa aagacacttg tcgaatgttc
    50941 gcctttttgc ttttcgatgg ctatgttacg ttctgcttca tttttatagt catatttttt
    51001 cggatcgatc gtttcaaatc cgtttggcac ataaaaacgc aagagatttt cttgattcag
    51061 cttatctgaa agacttaaag cagatttgac tttttcctga tctttggaaa tttcctcgtc
    51121 gattcctgct gctttcgtat cgatgatttc tcctgtttgg ttattgtaag cttttcctcc
    51181 taagatggtg tatttgggtg tcacgaagtt cccatttcga aaagccacta cttgatcatg
    51241 ctgaggagat aataaatccg taccaaaatg gagatagtct ttatcatcga ttcccaagag
    51301 atgaagtaat gtcggcaaaa catcgatttc tccaccgtat tcgtgattga ctgacccttt
    51361 agtataacca ggtatatgaa tcattaatgg cacacgctgc atttgtgcgt tgtcaaattc
    51421 attccatgta tctgggtctt ttccaagagc acttgctaag tctttattat ctgtatttga
    51481 gatgccaaaa tgatccccat aaatcacaaa gatcgaattt tggtaaatag cggatttttt
    51541 caggtacgta aaaaattgtt ccaatgactg atccaaataa tgtgccgttc gaacatagtt
    51601 atctactgtg ctatttccag tgttcaaaga tggaaaatcg aaattcttat catccgtata
    51661 ataaggcgtg tgattggtta cggaaaggaa tttcgtgtag aacggctgtt gtagatgttc
    51721 aagatattgg gcagattcac tgaataaatc tttatctaat attccataac ctagcgtttc
    51781 atctgattca tcaaaataag atcgatcaaa gaaattgtca taacctaagt ttttatatac
    51841 atgatctcta ttccaaaaac tagctacatt cccatggaaa acagcgcttg tatagccttg
    51901 cttttgtcca aggatcgctg gtgcggcttg aaagacatta tctgacccaa gttctgtgaa
    51961 taatgagcct tgaggtaaac caaatgtgcc agtttccaac atattttcag catcacttgt
    52021 ctttccctgt cctacttcat gaaaaaaatt atcaaagctg atcgttgctt gattctggaa
    52081 aatactattt aaaaacggtg tgacttcttg tccgtctacc ttcatattaa tcaaaaactg
    52141 ctggaaactt tctaaatgga gaacgatcac atttttccct ttagcgatcc caaatgtttc
    52201 gggatttggc tctgcataat gtttctttgt ataacgccga ttgtaaaatt aagctagaca
    52261 actaaaaaag tcatttgtgc tacactcaaa atagttccgt cgaaagaatt ataaggagtg
    52321 agtacaaatg acctataccc atcttacacc aactgaactc gtaatgatag aagcttattt
    52381 caatcaatca cactctgttt caaaagtagc ccatctggta caacgttctc gacaaaccat
    52441 ttataatgtc tatcgttttc ttaaatctgg tggaagcgca ataagctact atgaacaata
    52501 taagaaaaac aaacgtaact gcggaagacg tccgattgtg ttaccagatg ggcaacaaga
    52561 atacattcaa aaaaaggtgg ctcaagggtg gactccagat gtccttagtg gtcgagcaga
    52621 gtttcctatt gcttgttcgg tacgtacact atatcggatg tttaaagata aaacctttga
    52681 ccctcacgat ttaccaatga aagggaaaag aaaaccaaac ggacataaag aaaaaagagg
    52741 aaaacaagct tttcgccgtt cgattcagga tagaacaact gattatatac agttcaatca
    52801 tgagtttggt cacctagaag gtgacaccat tgtcggtgga aaacataaaa gtgcggtgat
    52861 cacgttagtt gagcgattat ctaaagtgat catcaccttg aaacccgctg gtaggcaagc
    52921 tatagatatt gagaatagac tgaatcaatg gtttcaatct gtaccgaaac acttgtttaa
    52981 atccatcaca tttgattgtg gaaaagagtt ctcgaattgg aaaaagatta gtaataccaa
    53041 tgatatttcg atttatttcg ctgatccagg aacaccttct caacgaggac taaatgaaca
    53101 ttcgaatggc ttattacgta aagatggctt atataaagct atggatttta ataaggtatc
    53161 cgaaaccttt atccaatcgg tggcatcaaa acgaaatcat attcctagaa aatcattaca
    53221 ctatcgcaca ccattggaag tatttttgag ttacgtaggt aaagatgatt tgtctagctt
    53281 aatttgacaa acgaaataat ctaaaacttc atcaatccca ttactgcttg catgcgcgcg
    53341 aacactgcta gtcattcctg ttttgattcc atcataaata gtatacgcat cgattcctag
    53401 atatttgaca atatatgaac ggtcaaatgt tcgctgcagc aattgtggac ggttggcttc
    53461 gctcagcgct agatttcctg aaaaaataag ccctgaaaga caggtcacag cgatagccat
    53521 cggtttgctg acaggttgac ttttgatagg tattttcttg atcgtcaacc aaaccagtat
    53581 cccaatgaac gtagcaatat ccagccagta gaggacatca tggggtttca tcaaagaaaa
    53641 ggagcttcct gataaccctt gcgacacttt cgaaaatccc aatacagatt tgactgtaat
    53701 gaaatctgtg aattcccgat aaaaaataat gttcaagtac aacaaaagcg tgtttaaaat
    53761 atcaatgatc aaaagaatgg ctaatgctgg ctttggcttt ttaatataca aagaaaggcc
    53821 aaaaaacaat aaggtagttg caatcgggtt gatccacaag ataaagtact ggatcgtacc
    53881 ttccacacct aacgaaaaat ctgcatagta agcaataatc gtcttcatcc agaaaaagaa
    53941 aacagctgtc aaaacgattg ctaaacgatt ttggcacaat tttttaagtt gtgtcacgta
    54001 tatcacttct ctctattcac atttttcctt attttgctcc tgaaaaatga aaattcccta
    54061 aaaaagttgt tatcttaaga tttttttatt ctttctaaag attattccgt gcacttttca
    54121 cagcataaaa ccgctgtgat ataagcgatt gaaacagtaa ggtgataaaa gtcttgtcgc
    54181 agctcctgtt tagttgatgc aggacagctt tttcacaact tcttctttaa acggtgttct
    54241 cctgccaact cctcggccac aagtcacaat atttataaaa catgagaagc tgttttttga
    54301 aattgttcct tgtggctcag agttaaacgg caagctcaag acctcttgat acacggtgtt
    54361 caatcagctg accttcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttgcc
    54421 gtttgtttct ctaatactca ggtcaaaacg ctgatttcac aacctctgtt tttcattgtc
    54481 cataggattg atattgtcct tgtgatgact cattcgtaat aattgaggct tgattttctt
    54541 cacttcccgt tatcgtttgt ccactgccag aatctgaagg acttgttcct gtcgactcgt
    54601 ttttttgaga agagacagtt gttttcttga cttgttcatt tgtctttttc cattccgcta
    54661 aacgatcggc gaccactttt ttgtctactt tttcagaata agcggtgatc acttttccat
    54721 ttttcaaacg ggctactttg tcgccatcat gagtcaaaag caaaacggtc aaatgcttgt
    54781 ctttaaattg atattgtctg agagaaatcg cactaagtac gtcatcgata ttaataaatt
    54841 gattttcttc ttttcctttt ggcaaataga tgtccaattc gcctttttcg taattggcag
    54901 ttattttata ctccgcccac caataagttg agaattcttt tttgaaatta tctactgatt
    54961 ctttgcttgc tacgattttt tctgtttctt tctgagcaag atctgctgtc atttttcctg
    55021 aaaatgctgc ggataaaata agcagtaaga aaaaaccgaa taaccaaaag agaagaaacg
    55081 gtcttttttt cctcatgctt tcctccactc ctatttaatt ttgactattc tattatatac
    55141 aaaaaatgaa atagaaagac aaaaaagttg aaaaagatcg taaataattg aacttctttt
    55201 tcacaaaatg gtaagaatgg agaatttcac gcatttgctc tcaactattc tttcttaagc
    55261 ctcaaatccg tttttatctg atacgtcttt gaaccagtga cccgattttt tgattgttct
    55321 ttttccatct tgtgctaagt ctactgaaat aaagccatat cgattcttat atgcattggt
    55381 ccatgaccag ttatccatac atgtccacat atgatagcct aaacaattgg caccttcttg
    55441 aattgcttga tggacatatt tcagatgaga ttggacaaat tcgatccgat aatcatcgtg
    55501 gatcatgcca tcttctttga taaatcgtgc ttcgttttct acacccatac cgttttcaga
    55561 aataaagcag tcgatatttc cataatgatc tcgtacattg atcaaaatat catagattcc
    55621 ttgttcatag atctcccatc cgcgataagg attcatttta cgaccaggca tttcataatt
    55681 gtcgaaataa tcctcaggca ttggaccgtt tttagtatcg attggtgttt cttttgcttt
    55741 tacccggcgt ggctggtaat aattgatacc taaaagatct actgtatttt ctttgatgac
    55801 cgtcaaatcc tctggatgga tcacaggcat gagatcaagt tcttttacta tctcaatcaa
    55861 ttcacttgga aactcgcctt ttacagctgg atcaaggaat gaacgattga agaacgcatc
    55921 tgctatttgc gctgctttaa catcttcagg gtttgattcg tctcttggat agcttggtgt
    55981 cagattcaag atgataccaa taacaccacc ttgctccatt tcatggtaag atttgatggc
    56041 taacgctgag gccaacgctt catgatagcc aacttggatc gcttttttca tatctgactc
    56101 ttctggataa tgccatcgat ataaataacc tgcttcgact ggaacgattg gttcattatg
    56161 agtaaaccat ttttttactt tcgaaccgaa caattcaaaa caacttttgg catatttttc
    56221 ataggcttca accgtttctc ggttcaacca tccgcctttt tcttgcagat acatcggcat
    56281 atcgaaatga tacagattca caaagggttc gataccgttt tcaatcaact catcaaaata
    56341 acgatgatag aaacgaacgg cttcttcgtt gattgttcca gattcatcag gtatcaagcg
    56401 gctccattgg atagatgttc gaaatgaatt atgcccagtc tgtttcatca actgtacatc
    56461 ctcttgatac ttcgtataaa cttgtgaagt tttttcaggt cctacttggt caaagaactt
    56521 ttgcggttct tttttgtacc aataatcaaa aatgttctct ccttttccat cacctgaaat
    56581 ccttccttct gtttgtgggc cacttgctgc agaaccccac caaaaatttg ctggaaattg
    56641 atattttttc atcaaagcac ctctttttct tttttagttc gttttagttg attccatgta
    56701 tgatattttc catcacaatt actttttcat tttcttcctc ttcttttttg attcgtttca
    56761 acagctgttc tgcggcttgt tccccgattt tatctgttgg tggtgtaatc gtgattttcg
    56821 gaaggatgct caaatcgttt ttatccaaat aatcataatg actaaacgca atatccttcc
    56881 cgattctgat accttcttga ttgaaacatt cgatagcacc gatcgacata ttataattgc
    56941 tgacaaaaat cgctgttact cctttttcta ataattcttt tgccccataa tagccacttt
    57001 ttctagaata gtctcctgta aagacctcta attggatcga tggatcattt tgtaccgctt
    57061 cttttgctcc tgctaaacgt tctcttgcta cgtagtctgt ttgagtggca gcaataaatc
    57121 cgattttttt atgtccttgt tcaccatgat gagcgatcac ttttgctaca ctttctcgat
    57181 cattcactaa tattgtatca atacctgctg gtccttctgg gcaattcaat gcgataactg
    57241 gaatactcat ttttgtgagc atttcaaatc cagaccactc ttcttcggat aagaagacaa
    57301 tcagcccatc gatcacatgc ttcatcaggt attcaatttt ttgttcaatt ttttctggct
    57361 gatcggcaaa cccgcttaat aataagctat acccattttc ttcagctact ctttcgatcc
    57421 ctgagacaac ttccgaccca aaacggctgg aaatcccgtt tatcaaaagt ccaatagaga
    57481 agcttcgatt attcttcaac cctttagcaa tgatgttttc tttatagtcc aacgctgaaa
    57541 tcgcttctgc tatttttttc atgttctttt ccttcagttg ctgaccattc aagtaacggg
    57601 aaactgttcc cactgaaaca ccagccatct tagccacgtc acggatcgat gccatacatt
    57661 ctcactcctg ccagttacat ttgatttctc tttcttgttg ttcgattatg atgaccgctt
    57721 tctttgcata gtgttgcttg tcatcaatat ccatataact aaagtcttca gtagagcaac
    57781 ttcctctcac tattaattat acttaaacaa gtatttgaac cggttcattt ttaatatagc
    57841 atttttttaa aagattgcaa cactttttta aaacgctttc ctaaaatggc gaattttttg
    57901 cctttttaaa attttattct aaaatttact ctatttgtgg gtgttttgtg cgtttttctc
    57961 ttccatccgt ttgaagtttt actttccaat ggtataattt ctttatccta tcaaatgggg
    58021 gaagtatttt gaagaaatta atcgtactat ttattttgtc tgcgggactt ttgacattga
    58081 ctggctgtaa tttgtttggc ggctctgacc aatcctcgga tgaaacaacc gattcttctg
    58141 tcttaaaagc ggaaaaagca gatatcacta acagtgtata tacgctaaaa gtacgtaaag
    58201 atatggattt atccgcggga cagttgacat ttacagataa aaaaatggaa tggacacgca
    58261 cgtatcagac acaagaaact gattcttctg aatcatctga agaaaaaaca gtgctgacag
    58321 acatcaagat tactaccaaa gatgacgaat atattatttc aggaaaagaa aataaaaaag
    58381 aagcaaccat cacatttacc aaaatcggta attaccgttt gaaggatgag gatggcaaca
    58441 tctacagtct atagtgccgt ctgttggatc ttcttttgtt tctccccttc ttttctgcta
    58501 tagtaaagaa gcaagatgat tgtaaaggag acgaaatgga tgatcgatag tcctgattat
    58561 tgtacatgta ataacaacaa aaatatccat acagaattta atgaccaagg aagcttgagc
    58621 atatgcgaca actgtcacaa actagtcaaa gattcattta aaacatttga atcttatcct
    58681 gttcaaaatt atgtaaaaag tagaagaaga taaacaaatc caagcaaaag tgactatggc
    58741 tggtttccag aaacttcgac tcagcttctt tctttgatca aatttcaaaa actagaagca
    58801 gtaaaacaag aagtggatca tttcagttca caaatcaaag agtaaagatt tatttatttc
    58861 aaatatttga atataaaata accaaacgat agaaaggctt attctacatc acgtagtaat
    58921 ttttctttcc cgtcgtttgg ttttttattt ttagcctaat tcttgacctt ttgcatgctg
    58981 attatccgta aaatattttc cagcaggctt tccttccaat tcagctaatt tttcttggat
    59041 ctgacggatc accttttttg catcttctgg attttctaca aaatcgaatt tatccccatc
    59101 cacttgtatt ttaggacata catcaaaatc ttcataccat tgattatagc gggtgttcaa
    59161 cgtttcgtaa taggtatata acgtttcatc gctttctagc tgttcatagt cacgcccacg
    59221 ttttttgata cgttctagca tcgtgtccaa agaaactttg atatggacca tcaaatcagg
    59281 ccgttttttt ggagcaacat catctaactc gtttagcatc gtatctaata agctatcgta
    59341 ctgctgtact tcgatatccg ttacccgacc taaatcagcg tttagatgga acaacaggct
    59401 atcttcatag atggatcggt ctagcacatt gtcatcgttc actaaagcat ttttcattgc
    59461 taaaaatcgc ttgttcaaaa agaagatttg caataaaaaa gcgtactgct caggatttga
    59521 ataaaagagc ggcaatactt cgttatcttc gacattttca taaaatggtt tagaatcaat
    59581 ctcttttgca agcatatccg tcaaactgct cttacctgca ccaatcgttc ctgaaatcaa
    59641 aatcactgac atacatccct tcctcttcta taagtactcg cctacgtaag tttcaacagg
    59701 caatgtttca aaatcatatt cacgtacagc ttggtctgat tttaaatacg tatggagact
    59761 ttgtgtaatc atcaagttcg taggtaccgt ctcttcttgt acaatgatca tcggtttttt
    59821 caacatagtt gccacaccta attcgtaagc cgttcctgga tcgattgttt gatgctcaaa
    59881 gtcaaggata gcaacaacaa attctgcatt tgtcagttct tccatatctt tttcgtatac
    59941 ttcctgcgcc catccagcgc tgaatagttc ataattgctt tcttggtgat gacgtggaga
    60001 gtagaaactt gtgactgttt tgttttcctc caacgctttt tcgatacgac ttactcgatc
    60061 gatttgctcc tctgaaaaaa atggtcctgc taaatatatt tgactcatta ttttgcctcc
    60121 ttcaataata actgattttt aatagatact gctcgtaatt cattgaccag ttccaatgga
    60181 ttgttggaaa agattacttg atccaaccat tttttatcca taaaatcctc ttttgcaaaa
    60241 gtttctaata attgttgcaa gccgctgtaa taaccgccaa tattcaatat tccgattggc
    60301 ttgtcaggcg tcagaccgat tgctatccaa gaaagaagtt gtgagaattc ctccaatgta
    60361 cctagacctc cagggaaaac gaggacagca tctccctttt caaataataa tacctttctt
    60421 tcatcgatcg tttctgtagg aataaatgta gtaacatctt ttccaggcaa ttcagtttca
    60481 aaaagcccat tcggatagat acctgtgact tttccgttat tttccagtac tgttttacta
    60541 atcactccca taatcccgga gtatgaacca ccgtaaacca gttcgatttc ttcttgtgcc
    60601 atgtattttc ctaacgtttg cgcaataaat ttgtaacttt ctttattacc aaaacgggaa
    60661 ccgcaaaaaa cagtaagttt cataaaaaaa cactccctaa ctcaaaagtc tatcttcatt
    60721 ctacacgtgt ttttttaaaa taaaagacta gattttgtag ttttttagtg gtatataaga
    60781 tagacaccac tatatatagt atttagaaaa aaatcatttt tcagctattt tatagataaa
    60841 acaaaaataa ataacgtgtt ttcatcgata tgaaatgact tacttataga agatactggg
    60901 atttcgtcct atatgccaat aacgtgtatt attttaaaca acaaatactt gtttctttta
    60961 ttaacgaaaa aatcattttg ttctcgtgtt atgtttcact gataaatgat gtttctctaa
    61021 ataaaaaagc cgacgaacta aacgatcaaa atttgatcat ttttgttcat cagcttctcc
    61081 taaaaatctt tttgttaacg ataaatagct ggatttgtaa aaatatcact tgaatcgtca
    61141 ctgctggaag aaaattcagt gataaccgca cctgttgcgc ctgcctggaa ctagtgtttg
    61201 atattgggct cgaacgtgta ctgatctcta gcatgaagaa taatttcttt ttttactgta
    61261 taataacttt ctttcctttt tggaatagta caggaaagtt tttttgtttc ctttccttcg
    61321 acataaggta tacgagacct tttcgacaac gaaaggttct catttttcct tcatcgtcat
    61381 ttcaaggagg gtgccgatgc tctggacagt ttcgatcgct cctaaaccaa aatctgtata
    61441 ttcgattctt tctaactctg attctttcat accattcctg cctcaaggta catctattgt
    61501 acttttttct tgtaatccat tctgcctctc ctaactaatt gtcaaatcat cccaagatat
    61561 gtcttcttcc tctttttctt cttggatgat ttctgcattc ggatctactg gttttttcaa
    61621 taataaaatg gttattcctg tgacaaaaga accagctaac aatgcaccaa tgaatgccca
    61681 tggtctggtc atcgtagcga ctgcaaacat tcccgatgcc ggaatacggc tatctgcgcc
    61741 ccaaaacatg cttaatccgc cacctactgc cccaccgact cccgttgcta tgacattgcg
    61801 tgccaagtcg ttcaatacga tagggaaaca tccctctgtg atctgacaga tccccatagg
    61861 aaaagcggtc ttcaatgtat cgatttcttg acgattgaat atatttttac gaatgatttt
    61921 ccctaagaaa taagcgatcg tcaagccgaa tggggttacc atcgaagcta aaatcaatac
    61981 agtgattggt tcatagattc cttctgaaaa tcgtgccaca cccccttatc cagaataaat
    62041 ggtaatccag aaacagccgt gtatctgcgg taataagcct aaccaaacga aaaatatgag
    62101 aagctatttt tgtttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct
    62161 ttttttattt atgtttcata atcaatatgg taaggatgca gctccgtatg gtagaccgcc
    62221 tccgaatatt caatcatttc cccaatttgc gtagacgatt tccgtatccg tttgatgccg
    62281 atctgtgcgt ctgttttcag aattccttgt tcttcttctg ttaaaaatac tgccgagaaa
    62341 tcatcagaaa atgagtcaat agtatatcct tttttcgtca gcaaacgata caaagattct
    62401 ttgccaaatt cttctctgct gaattgcatc atttcttgtg gaagataatg aacaaaataa
    62461 atataaggct gattgttcaa ataatataag cgcttaaaac aaacagcttg ctcaccgaaa
    62521 aaggaaaaca aaggatcttc cttctttata tggaccaatt gcaaatccag cgtttctttc
    62581 cggacttcat atcgggagtt ctccaagatt tgcgtaaagc ttgccgcttt ggataatcga
    62641 ttgtaaggac gattgcttag aaccgtcgtc ccacgaccac ttttctttgc gacatattca
    62701 tctgatgcca gcagttcgat tgcctttcgg acagtgattt tgctgacttg aaacagttct
    62761 tctaattcac tttctgtcgg taacatcgaa ccgactggat attttcctga gaaaatatct
    62821 tctttaattt tatctgcgac ttccaagtat agtacacgtg tccttttcat aacgtcaccc
    62881 tttgctttac tattactaaa agaatagcac ataaaaaata aaaaaagaac acaaatcaca
    62941 tgtgagaagt gtgttctttt tcattcagct gctttaatta caagtttacg ccatttgagg
    63001 caattacttc tttataccaa tcaaaagatt ttttctttga tcgattcagt gtcccatttc
    63061 cttcatcgtc tagatccaca tagataaagc cgtaacgttt actcatttct cctgttgatg
    63121 cactgacaag atccatacat ccccaaggcg tatagcccat caaatctaca ccgtctgcta
    63181 ctgcattagc catcgcttcg atatgacgac gtaaataatc gatccgataa tcatcaataa
    63241 tcgtgccatc ctcttccata tgatcaatgg ctccaagacc gttttcaaca atgaataatg
    63301 gtttctggta acgattgtat aattcattca atgcgattct cagcccttct ggatcgatct
    63361 gccagcccca ttcacttgcc tcaagaaacg gattttttac tcctcccagc aagttccctt
    63421 ctgaagttgc tgcttgtgga tcagtctcat tgattgccgt agacatataa taactaaatc
    63481 cgatgtagtc cactggatat tcttttagca actggaagtc tttttccgtt tgctctaatt
    63541 tttccggatc gactccatat tttttatggg tacgcgctgt gtatgcaggg tattctccac
    63601 gtacttggac atccgtgcag aaaaaattga attcttggtt ttggatcatt gttgctgcct
    63661 gattgactgg attggcatcg atgctgtaag ttgttgcata gataatcatg cagccgattt
    63721 ggatatccga acgcaattcg tggccgattt ttacagcttt gctacttgca acgaattgat
    63781 tatgccatgc ttggaaaata ttttggtact ctcctgctcc attgcttttt actaatcctt
    63841 gacttaaagc tggaaagtga aaggccgaat tgatttcatt gaaagtcatc caatatttga
    63901 ctttactgct gtatctctct aatactgtct gagcaaatcg ttcatagaag tcgatcagtt
    63961 ttcgattttt ccagccaccg tattcttttg ccaaatgaag aggcatttcg taatgagaaa
    64021 tcgtgatcac aggttcaata tcatatttta agcactcatc aatcagctga tcataaaatt
    64081 ctaatcccgc ttcgttagga gtaccttcgt ctccatttgg aaaaattcgt gtccaggcaa
    64141 tcgaaaaacg ataacatttg aatcccattt ccgcaaacaa ggcaagatct tctttgaaac
    64201 gatcgtaatg atcgattcct cgatgattcg ggtaaatata tttttcttga tcaatcgtcc
    64261 agtcaaattc ttcactgccg ataatcgcaa agcgctgctt acctccaggc atagcatctg
    64321 caacggatag cccttttccg tctcgatcat aagccccttc taattgattg gcagcagttg
    64381 ctccacccca taaaaatttt tctgaaaaac gtgattgcat cctgatttcc tccttatttt
    64441 acaattgcca gaacatcttc gtttgcaata atctcttttt ggtctaattc aagtatatcg
    64501 gcaaatgcat cagtattcgt aatgacaact ggagtgatta cgctatagcc agctgctcta
    64561 attgcttcga tgtcaaaacg aatcaataaa tctcctgctt ggacgagatc cccttgtttg
    64621 actaagatct caaagccatt cccatttaat tctactgtat ccatcccgat atgaatcaaa
    64681 atatccgctc cgtcagtcgt tgtgatccct acagcatgtc cagttggaaa aatagtcgtg
    64741 atctctccgt ctgcaggtgc aactagttct cctacttctg gatcaatagc gatacctttt
    64801 cccatcacgc cagaagaaaa aacttggtct ggtacttcac tcaatggcag tactttaccc
    64861 gttaaaggac tttttaaggt atgccgtgct gaagtaatcg gttctcctgc attcgcatgt
    64921 ttgttttcta attgattgtc ttgtgtttgt tcgtcaaatc ctaaaatcaa tgtacctacg
    64981 aatgcaagaa caaaagcaat tcctgtagct attactgcta ctgtcacatt tgactctaca
    65041 ccatccaccg tactaatgaa agtcggaatc gtcaataagc tgaccaaact gctggagaaa
    65101 gcttttactc cggaaaatcc gataatagct ccaccaatac ctccagaaat acaagcggca
    65161 atgaatggtt tcttcaaagg taatgtcaca ccatacacag ttggttcagt gattccaaat
    65221 aacgaagtca ctgtagaaga aatccctaat gctcgaagtt tcgtatcttt tgttcgcaat
    65281 gctacagcta aagcagcccc accttgtgcc aagatggctg gaagaagcat tggcatcaat
    65341 acatcaaacc catattgttc gatattcaaa aacatgatcg gtacgaatcc ccaatgcatg
    65401 ccgaacatca cgaatacttg ccataaactt cccatgatta gacctgctac gattggacta
    65461 aatccataaa tcgagttgaa gagaccgcct aaagcattac cggcaaccgt cccgattggt
    65521 cctaaagcaa gaaatgttaa tggaaccatc actactaaaa cgacaagcgg aactaaaatc
    65581 atttgcagaa attgcggaat cacttttttt tacgaatggc tctaatttac tttgaaccca
    65641 tacggctaga atgattggta tgacagaaga agtataacca gatggtgaaa gaatcactgg
    65701 gatcccaaag aaactgatag cttctcccgc accagcaact gctgtgatag ctggatacac
    65761 aagtgccata gcaattgcta ctgctaaaaa ctggttggct ttgaactttt tagctgctgt
    65821 aaaagcaagc atgacaggta agaaggtaaa gacaccatct gctgcagcaa acaatatttg
    65881 ataagtaccg ctatcagctg tcagccagcc catcaccgtt gccaatgata agaatccttt
    65941 caataccccg gcggctgcca tcgcccctag aaaaggtgta aatatactag agataatatc
    66001 gatcagacga ttcaaaatat ttttggactc ttcttttcca tcctccgaaa ctgcaagacc
    66061 ttcctcatcc acgatcgatt gataaacatc tgctacatta ctgccaatca ctacttgata
    66121 ctgaccgcca ctttgtacga cttggatcac gtccgggtct tcttttaact tttgcgtatc
    66181 tgctaaagat tcatctttta atctgaatcg caaccgcgta gcacaatgta ctaaactttt
    66241 gacattcttt tgtcctccta ccgcttccca tacacgacga ccaactgctt gattatccat
    66301 tgttttttcc ttctttcttt tttatttaaa aaataaaaac ccagattgaa aaaaacagtc
    66361 acaaacattc gtgaacctat tttttcaatc caggttttgc ctgccataca gtaacaatcc
    66421 ttatgattgg atgctttttt tctcacttac tactctttga atatgaatcg ttaaataaat
    66481 ctgctctgcg atccccattt cctgtttttg cgtttgtcga agatactcat tgatccgttc
    66541 gacacaatga aacgcttttg gatactttcc ttgaactaat gcgtagagaa attcatcttg
    66601 ctcgtcagat ccttcccctt tgagataacg ctgggcaaaa aactgcagat gagtaatgat
    66661 acgctgataa ttcaaagatt cttcatcgaa cacgatgccg aagaatttac tgatgatact
    66721 cagtatatct cttaccattg tggtagcggt catcgtcact tgcatgtctt cgtttccttg
    66781 ttggctattc acaaaatgaa aggcaataaa accggcttca tcctcagaaa gttccacacc
    66841 cgtcttttgt ttcacgaaca aaagagcctc tttcgctgct tgatattctt tcggataaaa
    66901 tttttttgtt tcaaataata atggattagg cagttggata ttttcttttg ctcgtgtgat
    66961 cgcataatga agatgatcgg tcaatgtcag ataaatatta ggcgaaaatt caacttttag
    67021 tttatcttca gccagttcga ctacttgttt gacccattcg atctcctctg ccggaatatc
    67081 agccatcagc tgctggaatt ggtttttagc aaaagaatct cttaaaacaa attctttttg
    67141 gaccgcttct agcgaaatct cgtccccaat cttttttttg aaaagctagt ccttttccca
    67201 tacaaacgac ttcttccccg aatccatttt tcgaaatgac gacattgtta ttcaaaattt
    67261 tatcaatttt cattttgctt cgccctctca agaaaaataa aaaaacctag aattcgccta
    67321 ctgtttctta gctgaattct ggttttgcct gccgtacagt aacaatccat ttcttattca
    67381 aaatcatcat accatcgaat ttttatttat gcaagccttt tcatataaaa aataaaaaaa
    67441 ctggaacaca agtctatcta gaaaacaacc aaatcagaga tgcacctctt tgcgttcctc
    67501 tttttttcag caaattggtt tttccttatc gattcatatc ctttggctgt ttttaatctg
    67561 taacgactta tgtcccagta tcctaaaatg tttttgtctc tagattgaaa gcagatctca
    67621 tatcatctgt cgcatctttt atcggtgtaa cactttccag ttctccttgt acaactagtc
    67681 gcgtgacggc gtccatgtcg ccacaagtaa ttagtgtgac aatttctttt tcctcgactt
    67741 cattcagtaa ttgggtatct gtaggagcaa ctttttcttt aaaaaatgtt ttgtatgtat
    67801 acacattttc taaatctgtc aaatagatct tggcacccat ctctaaattt tccagcggtg
    67861 taaacaacaa ttcagggttc gttgcacgat ggcttgctaa ggcataattt ccttttccca
    67921 tttcttgatc tggagataat gttcctgctc cgtaaagtag tgacgtatta tccaagcctt
    67981 tgaaaatcgg taaattgatt gaaactgaag ggactgcgat actagcaatc actggtagat
    68041 ctgttcctct catctgcgac ctcatgaccc cttctgtcgt cattggttct accgcatcaa
    68101 agtcaaaact gacatcttta tcgttattct ttttcagatc ttcttttgtt acattcgcta
    68161 tagcatattt atctcctgtc tctctgacaa gataatcctt gatctgttca ttgaaaatca
    68221 aagctagtcc tactaataac aagaggaaca agaggatatt gactagccat ctttttgctt
    68281 ttcctttttt tttcattttc tctccctcca gactcatttt actgtttttc ttttgctctt
    68341 tccaacagcc gaatgacaca tttctaaaac tctgtgtatt tttttcgtac acctgcgctt
    68401 ttttctacag gatatttcaa attatttttg atcaattttt cttcaatgat ctcatctaga
    68461 tccagctgaa ggttgtctgc catcatgtat gaatagatca atacatccgc cagttcttct
    68521 ttgattcgtt ctaattgtgt ttcttttact tcttccggcg ttttccattg aaaaagttct
    68581 aacaattcag atgcttccaa agaaatagaa atagccaaat ctttttcgtt atgaaattgt
    68641 cgccaattac gttcatctct aaactggtta actttttcca tgctattcat ttgcttgcct
    68701 tcttccaatc atttcttact tgattaatca taccattttt ttacataaaa aatagatgat
    68761 gcttttaaaa aaactcctgt tttcttttat ttaaaataaa tgtcatagaa atcagtaatt
    68821 taggtagcca ccatgtgtat gcagtaatgt gacttcttcc cctgaggctt tttgtttttc
    68881 gatacgttct tctccccaaa cagacatcgc tactagaatc tctcttaatg attttccttc
    68941 ttcggtgagc gagtactcta ctttaggcgg gacttggtta tagacttttc gatggacaat
    69001 gccatcttgt tctaactctc ttaactgctg ggtcagcatt ttttgtgtga tcgtagggat
    69061 tttcttgctt ctccacgcct aaaataagcg atattgctct tccctttatc tggtgtaagc
    69121 aaagcagtta gcattttgac gatcgtgggt tccgcttttc acttcttatc tacttagtat
    69181 catgaagtat actttcgtac taatactaag tagcggaagt gtcaactact ttgtttaact
    69241 acatagcaaa agaaacagaa gggtgacaac ggtcatcacg cttctgtttc ttttgaatat
    69301 gctgtgttgt tgtctctatc tccgtgtaga ctttcctcaa gcttatcctt tgacagtaag
    69361 tcagtaggct gatttgctct ttctagatgc cagatacatt tctacaaaaa aatagtgatt
    69421 ctgttttgaa aattcgattt ttagttctgc attttcgtaa acatccaaca tttttttcgc
    69481 actgtataga cctaacccgc catttttttt agaggttttt cctcttttga ccatctccga
    69541 tagcgtcaaa ttcgtcggat ttgccttgtt cgctatacta aaacgtaatc cctctttttc
    69601 ttccagcaga ttgatcgtaa tcggactctg atcggctaca cgatgatcga atgcgttaga
    69661 aataaaaata gataaacagc gaataaaaac aaccagatca atcgggattg ttttcacttc
    69721 gacaggaata actacttgga tcgggatttt ctccgattct gctttttcta gaaattttaa
    69781 aaagacaccc ctgacagctg gggatacaat atttgttagc tgttgtattt gcggtttttc
    69841 aaaaatagct gcagaatgat cttctaagat ttctaaaaat tccaacgttt cttttttatt
    69901 ttcctgaaga gtaattttta atgaaaacag tagactttta taatcatgtt tgaattcctc
    69961 tagatgatgg taatattctt catttatttg atacagttga agcgattcct gatgttgtct
    70021 ttcttttact tggaaactga tcaacataat ggaaaaaaac aaagaaaaaa aactgatgac
    70081 tatcgacaaa agagatagaa gcagataatt agatgagcgg aagtgaacac ttcccaatac
    70141 caagtaaatc acgccccagc ttaataaaat acaaatacct ccaaaatagt gttcagttgg
    70201 ataagtaaaa agcaagttga gaaatctcgt ctgtttgtct atacttttta ctaatagata
    70261 gaaaataaat gcgataagta gtgcaaaaaa acttgctgtt ccaagatgtc tctttcctaa
    70321 ataatccatc agatcaaaaa ccagaaaaaa gctgagtcca gtgatagcaa aaaaaagatt
    70381 actgatcaaa cagctgataa acaggttttt cgtagtaaaa taaaaaagaa acatcaataa
    70441 taagccaact aggtaaggaa agctcacttt agggatagga aataaaagtg tcaccaccat
    70501 caaagctata caaccaaagc tgttttttac tagcagttgt ttcgaaaaga ataaatagat
    70561 acctaaatct aaaatcaaag taaaggtcaa ataaagtgtc actgttgcga ccatcttatt
    70621 cctccattgt tttgtttcaa aatgtacaca tattttttta ataggagcct gcatatgaaa
    70681 aagtatttta tcatagaaga taaccagttt cacagcgaat ggatcatcaa agaattggtc
    70741 aatcatcata tcgagaatat cgtgcagctc acttctatct ctcaaatcaa tcagttgatc
    70801 cagttgggta ctattgataa tcacgatgtt ttctttatcg atatcgactt gaagcaatca
    70861 ctcacaggta ttgatgtcgc cgaacaaata cgtaaaaaaa atgcacatag taatattgtt
    70921 tttttcaccg cttatacgaa ttttgcagta gagatcatca atcggaaaat ccttccgatt
    70981 ggatatatca gaaaagacag gaatttatct gaacaaattc gtcaagtgct agaacagatc
    71041 aattggaaag aacagcaaat cgtaaatgtc gataaaatct ttattgatca aaaaggtgga
    71101 agtctcgtcc tgtatcctcg ggaaatttta tatattgaaa gtatcaaagg tttgaaaaac
    71161 caagttatgg tcaaaacaac tacagaagat aaattagtga atacttcttt aaaacaattg
    71221 aagacagagt tggaaaagta tgcttacttt ttactattaa aatcttactg tatcaactta
    71281 tcgcaattgc agaaaattga ttctgctcat tatgtgttag aatttttcaa tggtgactcc
    71341 ttactcgttg gtcgaaagat ctttgaaaag acaaaggaac gtttccatga cttccaaaaa
    71401 actgcttcga gttgatgaat aagagctgag acgtaagcat agcagatttc agggagttgg
    71461 ccttgaatcg gctccactcc ctgaagtcat tgatttgatt ttacgctttc ccttctgtag
    71521 gagcatctgt taacgaccat gtgaatgttg aaacgtagtt gtctacggca taattggata
    71581 caggaacaaa taattccact gattgtctcc cttgttccac attctctcct aatgaataaa
    71641 tccatgtgcc aatcccttca tttgctcctg cagttactag atctactgcc tgatctgctg
    71701 ggatctcaat tccttcagcg ccagtaccag aaatagtaga tggcgttcca ctgctattag
    71761 ttgcgctatt tcgaatcacg gcgtttttga atttcacctt tgaaccagtt agtttattcg
    71821 tatcagatgt tgtaccaata aattctgttc gtttgactga tagtttccaa ccggcataaa
    71881 ttccgctttt atccgttact tgtacgaaat tctgtacttg tgttgctgtc cctgtactgt
    71941 ccgttccgtt ttgtaatgca gcatatactg tttttgctgt acctaacttg attgttccaa
    72001 aatcaagatc tggagcttgg tcaatcgtca gtaatccgga tgttccctga tttggttcgt
    72061 taggtgtaaa cggcgtatcg ggatcatttg gatcaacagg aggaactgga acaacgtctt
    72121 caggatttgc ggcatctggt tttgttacag aaatcgttcc ttctgtagtg gctgagctct
    72181 tattctaagc aaaaacactt tgtgtacata ataatagact tccagctaga acggtactta
    72241 atgcaattgt ttttttcatt tctttttcct tctttctttt aaaataaata atccagcaaa
    72301 taagccaata agaatgactc caacaagtat cagccatcgc cagtcaaatg tttctggctg
    72361 attttttaaa tcaatatcct tttcattcaa ttggtccgct gcatcatcag ttatttcaaa
    72421 atcggtatgg agattccagc gtttttcttt ccaagcaccc ttcacaaccg cttgataatg
    72481 tcccggagct aatttttttc cttctaatgg gacaagtaaa tcaaaatttg tattgggtgc
    72541 tacatctatt ttttcttttt ttattgaaag ataaggctct tttgtttctt ttttgtagat
    72601 ttcaaccgat gtagtcaagc cgaacatata agaagcattt ggattttgaa gattcgcctt
    72661 aatcacattt cttccatcgc tttgatccgc ataagctttt tttaatttca aatttgggga
    72721 agactctttt tcgctatttc gaatcaagat tgctttcact tgagaaaact gattgacgac
    72781 accaactgta cttttgttag aaacgttctc ttttttttct tgaaacgtga ttcctcctgc
    72841 gaccacacca gccagctctt tttctggagc tttcagtgaa agtgtctcag tgaccgcact
    72901 ttgaggaggg acagttattt ctcccactgt ttttgctaag tttttcatat cataacttaa
    72961 tgtttcatca aatttacttt ttgattctcc atattcgatc acaccgtttg aattcgtcgt
    73021 agcggagtgg atcaatgtct caactgttac tgatttatct gttcggttaa agaccgtgta
    73081 ggggatttcc tgtgttttcc caggctccat ccttacattt atatatgttt tgttcttatc
    73141 aatctgatta gccggtaatt caaaatctac cgcaaaattg aattcggagg catggacagg
    73201 tgtctgccaa aggatgaatc caaggagaag gatcagaagt aaagagcagt tgtttcgatg
    73261 acttttattc catattcgat tcatcaatca ttctccttga tctttattct gtcggcgcat
    73321 ctgctaatgt ccatgtcatc tctgctgagt aattaccagc tatctgattt tctttggtta
    73381 agacaagttt aaacgcccga ccattattta aatattctga ataatctgtt tgcacattcg
    73441 ttgaattttg tcctctgaca atttccagtt cttcttcatt cactaattga tactcctcag
    73501 ctttcttgaa atataggaca tcctgcatag aaaatcctgc atcggttgtg aaaggctgag
    73561 ataattttat cgttaagatc catggacttt ttgtttctcg ctgatcataa atccataatt
    73621 tttcctgtat atccatttgg ccaaatgctt cttgcgtcaa cccagttgct ttgatctgac
    73681 cacaatcgag tttggaaggg gcaagaaatg agagaccacc ttctactaca atcttcgtag
    73741 caggtgcaaa aggcggggca tcatgataaa caactggcgt atcacttgga ttgtgattcc
    73801 caatttcatc gttggtactt ggcttgttct gcacaccctt agcagcagct tctcctgctt
    73861 ggtcgtttaa tacaatttct aatacatctc ctgcaaaaag ttgattttct gggatagaaa
    73921 gaacaaattt acctgtatca tcaatagttg tttcggacaa aacagcttga ttttttttca
    73981 atgaaaccaa agctcctgct tcgcctgtac ctgtgattga gcgagaagct gcattgatca
    74041 atgtggtact taatttagca ggctcaggag gaatcacatc gactgtcgtt ttggcagagt
    74101 ccagttctgt cacttcttgg ccgcctctta cttttttagc agcaactatt tgcacttgat
    74161 cccccgttgt tagtctttct tcgttgggta cttgaacctc aaacaaaccg ccttgttcgc
    74221 cttctcccca cggattatat cctgtccctt cattttcatc tgtttgtcct tgtgtgagag
    74281 cagtaatttc tacaggtgat ttcgtcgtat ctgcataagt aatacgtaaa gtcacttcta
    74341 cttcgcctgt ccaagcatct cttggctttg cctcgacacc ttcgggaaca acgacatgcc
    74401 catagatttt tttatctgca ttcgttggta ctcttaagga ttcaatcatc ggaagctggt
    74461 tattggcact gattcgatta taatttttca ttccggcacc tgtctgagca aattcatttg
    74521 ttaaacctgc actagggctt gatacaaaat tacctaagtc ggttccattg atcgataagt
    74581 ctgtcatatc agaaaaataa tccggatctt tttcaaagtt atcgaacgtt actcctgcct
    74641 ttcgccataa agcaatttct gaatgagcga tcttcaaaga agaatcgcca tttccttgaa
    74701 atacccagcc acctatgcca ttagtctcgc ttccgatccg tttgttttgg aaatcgaaat
    74761 aggtaggaga ttctaagtct acattcaaca catccccact gatgatgcca gtcttatctt
    74821 ccccagtttt cccgaccatg actaaataag ttttttcgcc agccataaag ttcaaatcaa
    74881 tatctccagt tgtatctacg gtagctccgg aatctgcgcg tatatcgata tttgattttt
    74941 ctccagtaac cgtaaaatca gctgaccctg gactttctag aaaaccagaa gcgtcataaa
    75001 attggatcgc ttggtttcct tgattgagtc tgttcacata agatttgcca tcccctgcat
    75061 ttcttacctt caatgagcct ccattagtta ctgttagttt ttgcgtaccg ttctcaaaac
    75121 gaactgcgct agaacgacca ctttgcttat caatatcgat gactgatccg gctccttcta
    75181 cgatcaaaga aagtcctttc cctacaaaac gcatcccatt gtttccaggt tggtcgccat
    75241 ctccagccat tttgaccgag atttgtccac cacttgatac atggatttga ctagaatctc
    75301 cttgcaggcg aaatccgcca gtagtcgctg tattgattgt gattttccca tcattcgaca
    75361 cagcgactct tgatcctgag cctctcattt ggataattcc gcgattgttg tcgttggtaa
    75421 tattgatctt tgtatttacc gaaaattcac ttcctgagcc actgacttta aatgtgacat
    75481 tcccgggtag cgtatcgaca gcctctcctt catcgctgac gccatctgcc cgatcatagt
    75541 aaagagagac ctttgaacca ctcaagatat ggagtcctgg tgctgttttt ccactgcccg
    75601 tctcatcacc tgaatctaga aaaccataga attttcctag atatggtcca taaagctgac
    75661 taccattgat tacatttagc tgatagcttc tacaaaaata agctttaccc ggagcggcat
    75721 tcatcccttc tttcactggt tggacatcca atacaccgga aacaccatct aatgtgacag
    75781 ttgcacgagg ggcgtaaatc aggcctaatt tagaaccatc atataagtca agtgtcccgg
    75841 taaattttat ttctcccgta aaatgatatc tgtttcccca aaaatcggac atataagcaa
    75901 tgataatggc atttccatcg atatttggta tcaacccacc tggatgagct gccgttcctt
    75961 taaaattctg aaactcgatc gactgaggtg tctcattgat atagatgtga tgtgtgccga
    76021 aattatgagc aagtccgcca aaatcgataa cgatatctcg cttgatctcc aattccctgt
    76081 ctaaagtcaa aggctgagtt aaacgaatct tagctactga ttcgtctgcg agaagctgcg
    76141 tcagttcttc tgttgtggca gcttcgctgt acccatccgc tgaaacaact ctaacctgta
    76201 cctcttcact gctatcagac gtttgttcag ctacttctga ggtctcactt gtcttatttt
    76261 cttcttgcct tgtattagaa gtaggcgcct cactttggga ttctgtagtt tcagaagtaa
    76321 ttgattcttc tgaaaaagta gtcttgtcaa aactttgatt ctctgattgc gttgattcgc
    76381 ttgttttctc tacatcggca aaaacggatg tcaccatcaa gagagggaag acaaacaaaa
    76441 tcgacgcaat cagctttttt acatattgat tcattctcca ccatcctctc tgacgttttg
    76501 acaattttat tttaacgttt taatttattt gtaattgtac tttcatattt aaa
//
LOCUS       DAPBCF010000008        63278 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.008, whole genome shotgun sequence.
ACCESSION   DAPBCF010000008 DAPBCF010000000
VERSION     DAPBCF010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 63278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63278
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.008"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(96..494)
                     /locus_tag="RD508_000694"
     CDS             complement(96..494)
                     /locus_tag="RD508_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HDT7735310.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(491..1264)
                     /locus_tag="RD508_000695"
     CDS             complement(491..1264)
                     /locus_tag="RD508_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HDT7735311.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1261..1944)
                     /locus_tag="RD508_000696"
     CDS             complement(1261..1944)
                     /locus_tag="RD508_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HDT7735312.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2111..2998)
                     /locus_tag="RD508_000697"
     CDS             complement(2111..2998)
                     /locus_tag="RD508_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7735313.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(2995..3864)
                     /locus_tag="RD508_000698"
     CDS             complement(2995..3864)
                     /locus_tag="RD508_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7735314.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4001..5287)
                     /locus_tag="RD508_000699"
     CDS             complement(4001..5287)
                     /locus_tag="RD508_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7735315.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5560..6138
                     /locus_tag="RD508_000700"
     CDS             5560..6138
                     /locus_tag="RD508_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDT7735316.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6138..7067
                     /locus_tag="RD508_000701"
     CDS             6138..7067
                     /locus_tag="RD508_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7735317.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7064..8800
                     /locus_tag="RD508_000702"
     CDS             7064..8800
                     /locus_tag="RD508_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDT7735318.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8863..9699)
                     /gene="pheA"
                     /locus_tag="RD508_000703"
     CDS             complement(8863..9699)
                     /gene="pheA"
                     /locus_tag="RD508_000703"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HDT7735319.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9696..10205)
                     /locus_tag="RD508_000704"
     CDS             complement(9696..10205)
                     /locus_tag="RD508_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HDT7735320.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10198..11493)
                     /gene="aroA"
                     /locus_tag="RD508_000705"
     CDS             complement(10198..11493)
                     /gene="aroA"
                     /locus_tag="RD508_000705"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDT7735321.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMSADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11506..12597)
                     /locus_tag="RD508_000706"
     CDS             complement(11506..12597)
                     /locus_tag="RD508_000706"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HDT7735322.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12614..13780)
                     /gene="aroC"
                     /locus_tag="RD508_000707"
     CDS             complement(12614..13780)
                     /gene="aroC"
                     /locus_tag="RD508_000707"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDT7735323.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13782..14846)
                     /gene="aroB"
                     /locus_tag="RD508_000708"
     CDS             complement(13782..14846)
                     /gene="aroB"
                     /locus_tag="RD508_000708"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDT7735324.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14879..15901)
                     /gene="aroF"
                     /locus_tag="RD508_000709"
     CDS             complement(14879..15901)
                     /gene="aroF"
                     /locus_tag="RD508_000709"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDT7735325.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16560..17534)
                     /locus_tag="RD508_000710"
     CDS             complement(16560..17534)
                     /locus_tag="RD508_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HDT7735326.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17515..19398)
                     /locus_tag="RD508_000711"
     CDS             complement(17515..19398)
                     /locus_tag="RD508_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HDT7735327.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDIK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19416..21641)
                     /locus_tag="RD508_000712"
     CDS             complement(19416..21641)
                     /locus_tag="RD508_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HDT7735328.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21756..22790
                     /locus_tag="RD508_000713"
     CDS             21756..22790
                     /locus_tag="RD508_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7735329.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(22857..23870)
                     /locus_tag="RD508_000714"
     CDS             complement(22857..23870)
                     /locus_tag="RD508_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7735330.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(23948..24136)
                     /locus_tag="RD508_000715"
     CDS             complement(23948..24136)
                     /locus_tag="RD508_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HDT7735331.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(24576..24704)
                     /locus_tag="RD508_000716"
     CDS             complement(24576..24704)
                     /locus_tag="RD508_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDT7735332.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(24707..26080)
                     /gene="rlmD"
                     /locus_tag="RD508_000717"
     CDS             complement(24707..26080)
                     /gene="rlmD"
                     /locus_tag="RD508_000717"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDT7735333.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(26191..27246)
                     /locus_tag="RD508_000718"
     CDS             complement(26191..27246)
                     /locus_tag="RD508_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDT7735334.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(27256..28686)
                     /gene="gatB"
                     /locus_tag="RD508_000719"
     CDS             complement(27256..28686)
                     /gene="gatB"
                     /locus_tag="RD508_000719"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HDT7735335.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(28683..30155)
                     /gene="gatA"
                     /locus_tag="RD508_000720"
     CDS             complement(28683..30155)
                     /gene="gatA"
                     /locus_tag="RD508_000720"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HDT7735336.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(30155..30460)
                     /gene="gatC"
                     /locus_tag="RD508_000721"
     CDS             complement(30155..30460)
                     /gene="gatC"
                     /locus_tag="RD508_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HDT7735337.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(30566..32602)
                     /gene="ligA"
                     /locus_tag="RD508_000722"
     CDS             complement(30566..32602)
                     /gene="ligA"
                     /locus_tag="RD508_000722"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDT7735338.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(32619..34853)
                     /gene="pcrA"
                     /locus_tag="RD508_000723"
     CDS             complement(32619..34853)
                     /gene="pcrA"
                     /locus_tag="RD508_000723"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HDT7735339.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            35008..36567
                     /locus_tag="RD508_000724"
     CDS             35008..36567
                     /locus_tag="RD508_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HDT7735340.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(36678..38609)
                     /locus_tag="RD508_000725"
     CDS             complement(36678..38609)
                     /locus_tag="RD508_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7735341.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(38627..39541)
                     /gene="pfkB"
                     /locus_tag="RD508_000726"
     CDS             complement(38627..39541)
                     /gene="pfkB"
                     /locus_tag="RD508_000726"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDT7735342.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(39538..40290)
                     /locus_tag="RD508_000727"
     CDS             complement(39538..40290)
                     /locus_tag="RD508_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7735343.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(40450..40659)
                     /locus_tag="RD508_000728"
     CDS             complement(40450..40659)
                     /locus_tag="RD508_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735344.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(40670..41998)
                     /locus_tag="RD508_000729"
     CDS             complement(40670..41998)
                     /locus_tag="RD508_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735345.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            42134..42289
                     /locus_tag="RD508_000730"
     CDS             42134..42289
                     /locus_tag="RD508_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735346.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(42363..42950)
                     /locus_tag="RD508_000731"
     CDS             complement(42363..42950)
                     /locus_tag="RD508_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDT7735347.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(43033..44283)
                     /gene="clpX"
                     /locus_tag="RD508_000732"
     CDS             complement(43033..44283)
                     /gene="clpX"
                     /locus_tag="RD508_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDT7735348.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(44530..45819)
                     /locus_tag="RD508_000733"
     CDS             complement(44530..45819)
                     /locus_tag="RD508_000733"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDT7735349.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(45973..46905)
                     /locus_tag="RD508_000734"
     CDS             complement(45973..46905)
                     /locus_tag="RD508_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735350.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(47062..47721)
                     /locus_tag="RD508_000735"
     CDS             complement(47062..47721)
                     /locus_tag="RD508_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HDT7735351.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(47724..48749)
                     /gene="sppA"
                     /locus_tag="RD508_000736"
     CDS             complement(47724..48749)
                     /gene="sppA"
                     /locus_tag="RD508_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HDT7735352.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEKGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(48762..49052)
                     /locus_tag="RD508_000737"
     CDS             complement(48762..49052)
                     /locus_tag="RD508_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735353.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            49461..51266
                     /gene="glmS"
                     /locus_tag="RD508_000738"
     CDS             49461..51266
                     /gene="glmS"
                     /locus_tag="RD508_000738"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDT7735354.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINCLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(51338..52693)
                     /locus_tag="RD508_000739"
     CDS             complement(51338..52693)
                     /locus_tag="RD508_000739"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDT7735355.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(52717..53886)
                     /locus_tag="RD508_000740"
     CDS             complement(52717..53886)
                     /locus_tag="RD508_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735356.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(53883..54770)
                     /locus_tag="RD508_000741"
     CDS             complement(53883..54770)
                     /locus_tag="RD508_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HDT7735357.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(54959..58651)
                     /gene="nifJ"
                     /locus_tag="RD508_000742"
     CDS             complement(54959..58651)
                     /gene="nifJ"
                     /locus_tag="RD508_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDT7735358.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            58850..59371
                     /locus_tag="RD508_000743"
     CDS             58850..59371
                     /locus_tag="RD508_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HDT7735359.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(60070..60627)
                     /locus_tag="RD508_000744"
     CDS             complement(60070..60627)
                     /locus_tag="RD508_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735360.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(60806..61417)
                     /locus_tag="RD508_000745"
     CDS             complement(60806..61417)
                     /locus_tag="RD508_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735361.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(61530..61787)
                     /locus_tag="RD508_000746"
     CDS             complement(61530..61787)
                     /locus_tag="RD508_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735362.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(62384..62662)
                     /locus_tag="RD508_000747"
     CDS             complement(62384..62662)
                     /locus_tag="RD508_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735363.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(62696..62947)
                     /locus_tag="RD508_000748"
     CDS             complement(62696..62947)
                     /locus_tag="RD508_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735364.1"
                     /translation="MKEKPVNKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT        17608 a        13704 c        11201 g        20765 t
ORIGIN      
        1 tttcataagt attcacgaga aaaatacaaa caaaaaagcg gaaataacgc tcatccgcct
       61 tcttgtttgt gtttatttcc tcttcaaacg cttgtctatg attcagactt ttctctatcg
      121 ttattttcat ctaaaagttc ttgcattccg ataatttctc gatattgatg aatcttagtg
      181 ataccaatga ctttgtctac atcaatacta aaacaaatac cattacctgg aatatcgatg
      241 ttgatgcctt gaccaatcgc atccattact ttattcgtca aactatcggg tactaatgtc
      301 aacacaatat ctttttctgg cgaaatgtcc aaacctaaaa atttccctga atcatgtaca
      361 ccagaacctc ttccatgtaa gatcgttccg cctgctgcac ctgcttcttt tgaaaagtcg
      421 ataacatctt cgcccattcc tccgtcaacg atcgtcacaa tcatgtgaag attcaatgct
      481 acaagatctt tcatttgctt tcccccaatt tttgcaatct ttctttttcg attctgtctt
      541 tttcatcttt tcgtttataa atatatccta gtactaaagt ggataatatt ggtgtcaatg
      601 caatcattgc aaccacacca aacccgtcaa tgatcggatc tcttccttca atttgtgcag
      661 cgattgccac gctcattgat aaaataaatg tcgaacacat cgggcccgtt gctactccac
      721 cgttatcaaa agccattgct aaaaagatct tgtccacttt tcgtcctaaa ataaatgcta
      781 gcccgtatcc tgggatcaag aaataataaa gagagaatcc gacgagcaaa cgccacatag
      841 acaatcctac tgctgcgccg atcccaattg aaattaccat cagcatgatt ttcgatcgga
      901 ttctcccctc gctcaattct tcaacctgtt tgatcattac atgaatcgcc ggctcagcaa
      961 accctactaa gaaccccatt aaaaagccaa ggggaaccag tatataattg taaggcaatc
     1021 ccgcaatagc actgcctaaa tgctgtccta ccggtacata agccatattg actccgtgca
     1081 ggaaaaggat caacccaata gtcgttatca agaaaccttt cataatgtca aagaaacgct
     1141 ttttgcgcat acgaaaacta atgatattca ttaaaacaaa taggattacg ataggtgcca
     1201 ctgccaaaat gacttccatg gtaacgattt cgattccatc tatcacttgc tgccagaaac
     1261 tcattggaag atcaccccca aaatcatcac ggcaagaatc ggccctaacg aagcaatacc
     1321 gaccattcca aaactgtcat tttcattttt cttttgtttg atcatactag tcatccctcc
     1381 ggcaagggcc aagataaatg gaacagttac tggaccagta gtcactcccc ccgaatcaaa
     1441 agcaatcggc ataaattcgg aactggtgaa aaatgaggcg atcaaaacgc ctatgtagcc
     1501 tatagccatc aattgataat aggatagctt gaatacgacc cgaagcagcg caaaggctag
     1561 aaatactcca gtgccgacgc tgacgatccc aatcagcaac actctgccaa tctctccgtc
     1621 agatatatca tatacttgtt gtcccaaaac ttgcacggaa ggttcagcaa tcgtgatcac
     1681 gatcccgata gcaaatccca aactgaccaa aacggtcaaa cttttctttt tgatcatata
     1741 tttccctact agatctccga cttccatcat agaataatct gctccaaaca aaaagagcgt
     1801 cattccgatc atcatgattg ccgcaccaac cagaaatgaa gcgaggtctt ctccttctaa
     1861 cggtgcaaaa acaaacgtta aaatgacaat caggacagtc atcggcaata tagcagcaat
     1921 cacttcttta aaatttttta gcatgtatcc tcctccttta ctctttaagt ttaccttaaa
     1981 atgaaagagt tttcgagcac aaacttaaaa cgttatcatt taatttttct caacataaaa
     2041 taacacacgt cccaaaagta tctttttact tggaaaaatg actttgaagg aacgcgctta
     2101 ttgtgttttt ttattttaca gagccgatca ttccttgaac gaattgcttt tgcaaaacaa
     2161 aaaatacgat ggcagttggt aaagtagcga tgactaatcc agccatgatc attccatagt
     2221 ctggtgtata ggaagcaccc atagcagata aaacaagcgg aaccgtccgt ttatcaggag
     2281 attgcaaagc tactaagggc cataaataat tgttccagct actcatgaat gtgatgattg
     2341 cagccgcggc ataggtattt ttagccgtcg gcatatacac tctaaaaaaa atacttagtt
     2401 cttttagacc gtctaatcga gcggcttcta ctagatcttt tggaaaagat ttaacatttt
     2461 gtcgaaagaa gaagatcaaa aaagcagtgc taacagatgg caggatgaca accaagaaac
     2521 tgttgattcc caaaaccgtt ccgttcaatt gtgaaaacat tcgatataaa gggatcatca
     2581 atgccgcaaa aggaaccatc atcgatagca gtagaatatt gaaaattagg tcttttcgtt
     2641 tactttgata aatctcaaat ccatatcctg ccattgacga aatcagcaat gcaaacacag
     2701 tggtcaccaa agcgatcatc gctgaattcc aaagggaacg agtaaaattc agctcattgg
     2761 aaaacaaatt ttgaaaattg atgatcaagt tactgccaat ctttattttt cccgatgtga
     2821 tatccacggg tgtattcgtc attcccaaaa ccatccagac aaaagggaaa atggaaataa
     2881 atgataggat gcttaatgct gtatacttta atactgaccc aattgtcgaa cgaagttcta
     2941 atgcttgttt tttgacgttg gggcgttcga ttgtttcttt ttctaccata tttttcatcg
     3001 actttctcct cctactttcg tttggattat cgacaatatc acaataaagg aaacaataac
     3061 aaaggaaact gctgccgcat atccaaaatt aggcgtgaat ttataactca aattatagat
     3121 gtattgagat agggtggtcg ttgcatttgc tggtcccccg ccagtaatat tttgtacttc
     3181 atcaaaaagc tgcaatgtcc cgatcgtcga agtaatggaa gtaaacaaaa tgattggttt
     3241 taaatttggg atcgtcactt tgataaactg ctgccattta gaagcaccgt caatagatgc
     3301 tgcttcataa atctccgaat caatattttg catgcctgaa aggaaaaaaa tcatattgta
     3361 tccagtccaa cgccaagtga tcgaaagaat gatcagaact ctcgcccaaa ttggatgagt
     3421 caaccagcca atcggtgtgt caatcatacc aatgcccaac aacaagttgt ttacaaggcc
     3481 agattgagaa aatagacttt tcatgatcag agaataactg accatcgaag tgatacatgg
     3541 aagaaagata gcggttcgaa acaacccttt atatttcaac tttttatcat ttaaaaggtt
     3601 ggaaataaaa agtgctagaa acaacatgat cggtacttgt acaagtaaat acaggaatgt
     3661 attaaaaaaa gcttttttaa aagttgcatc tgtcaacatc cgctgataat tacctaaccc
     3721 gttaaatgtc atattgacag ggggaccact ttgaaaagac gtgatcaaag ccaaaaccat
     3781 cggaataaaa accatgattg atatcaaaat gactggcaag attaaaaaag catgcccgtt
     3841 tttgaataaa tctttctgct tcattctttt ccctccaatt ctatcattga ttatctacat
     3901 gaaaagacaa gaaagacaat atctgtaagg cagacgtgat cttttttgtc ttttcgtttg
     3961 tctgatgaaa aagcgaagaa attcactttt ttaccaccga tcaattagcc aattgtgctt
     4021 ctacttgttt ttgtgtatct gctagtacct tgtctgtctc ttctccattg atgattcgat
     4081 gaagagcttc agctacgact gcttcaattg cataggtctc atgtccgtaa ttcacttctg
     4141 gtatttcaga tgtccatgtt gaaaaatcgt caaagatctt ttgaccactg taaaattcag
     4201 aagcttcttg ataagcttct tgttcattcg cgctaagcat cgtagatact agtccgattt
     4261 ctttcgcaag agtgcccatc agttcttcat tcgaagcaaa cgttgcttct aggaaatctt
     4321 tcgctgaatc ttctccagct actcctttga tcacatacca gccagcgccg ccaaggttag
     4381 aagcttgcgc tttttgcaga ttttctggaa gtgcaggtat tggtgcaatc ttccattttc
     4441 cagattggtt ttctgctcct tggatcgttg aagaatacca agcgccagtt gggctagaag
     4501 ctactgctcc tgattgtatc gcagttactc cagcattcca gtcagaggtt tgttcgacta
     4561 gatcttcttt caaaagagtg gcaaacaatt caagaccata ctttaaagat gcattgtctt
     4621 ggatcgtgac tgtctcccca tcttcagatg tataccattc tcctgcctgt tgcataatca
     4681 tccttactcg accaaggtca gaaggattga cttcagcgat tttctttccc gtcttttctt
     4741 tgacatctcg cgctacttga atatactcgt cccacttcag attctccata tcctcttctg
     4801 tataacctgc ttctgccatc agatccgtac gatagaagtt tgctgttacg cccgaatcga
     4861 aaggaacacc gtatatttta tctcctactt tgtttaccgc aaatttatac ggtgcaaaat
     4921 gatcttcctt tacaatagca gacaaattag cgaatgcatc tggataagaa gtcaaatagc
     4981 cttgtatcct ataatcttca atcaagacga tattgggcaa tccttctgta ttcccgctcg
     5041 ctaaagcggt gttcagtttc tgaacgatat catcctgaga catcgtaaca acttctatct
     5101 ctgtttcttc gttctcataa actttttttg cttcattcac tgctttgata ttgaatgtct
     5161 catcccacgc ccagacagtg actttttctt ctttgtctgc tgtactacta gcacttccgc
     5221 atcctgttaa gaaacctgat gctgccgcta aacaaacgac tccagcaatt aactttctga
     5281 tgttcatttt tatccgctcc ttttccatcc attagttgtt tacgtttgct acattcatca
     5341 taccaaaatt tgaaaacggt ttctttatta ttcagatact tcaaaaattt ctcctaaaat
     5401 aataaaaaaa tacaaatcaa ctatgacaaa aggaataatc ttagcatcta gaccaaagat
     5461 cgaaatggtg aggtttcttt aaaataaaaa tatccttgca ttttctccta gaaataagta
     5521 tttttaaatt acaagactat tcttaaggcg ggtaaaaaaa tgccaatacg cgtaattctt
     5581 atcgatgatg aacagacgat tttagatgga atgaaacagt tgatcaattg gtctgagcac
     5641 gggtttcaat taatagggac tttttccagt ccgctgaaag cgcttgattt ttctttggta
     5701 catgcaatcg atatcgtggt cacagatgta atgatgcctg aattaaatgg aatcgaatta
     5761 tcgcggctat taaaacagca acaacctgaa acacagatcc ttatcctctc tagctatgat
     5821 gaatttgata tggttaaaga ttcttttaaa gaaggcgtcg ctgattatct tttaaagcct
     5881 cgattgagtc ctgatttttt tctaaattcc ttaactgccg tttcacaaaa aatcaaaaaa
     5941 aagcccaaca aaagcccaat caccaatcgt tatgagcaga tctgcgagaa tctttcacag
     6001 cagattgctg gacaaactcg tccattgctt gaccctcttc tttttgaaca caccttgttt
     6061 ttctgttata taccgaaaaa cggccattca gttcaaaaca aggctctaaa caaaaacagt
     6121 cgatcaccca ttcattgatg gatagcgacg attcgtttac tatttatcct gtttctacct
     6181 tttcggaaga atccggctat gtaatcaata ctgattccaa agatacactt aggaagtttg
     6241 ttcaaaagtt tcgtcaagaa gtttttccag gtgatttttt tgttgtttct gattcttttg
     6301 caatccaaga tatcaatgaa atattccaag agatcagaaa ttgcaccaaa ggacaacgtt
     6361 tctatcataa gggaaagaac cttgcttatc agcatgaact tcttccgtta ttaaccaacc
     6421 acgagcagca agcaagtagt tatttaacaa aaatcgttca taaagactac gctttagctg
     6481 tcaaagaact tgagaatttc ttcacgacga tattggaaca gcctattgat ccagcttatt
     6541 tgaaacatga ggcaatcaat cgtttctatg cattactcaa cgctttggct gacgagcatg
     6601 ttgggaatga agaactttct ttgctcaaga tcgcccttcc ttctttatta gccgatgctg
     6661 agtatttcga agatttttct attcttgtca aagaaacact tgagaaactc acccactttt
     6721 ctgcaaatgc aaaaaaagac aatttcgata tcttgacttt gatctacgag ttcgtccagg
     6781 aaaattatga gaaagaaatc aatttacaac ttttatccga aaaatatcat ttttcatata
     6841 gctatctctc agccatcttt actgaaaaat ttggtatcaa cttttcaaaa tatctaaaaa
     6901 aagtccgtat cagtaaagcc aagctctttt tgacggaaac acggcttact ttgacggaaa
     6961 tctgtgagaa agtcggctat accgaactgg gttatttctc cagagttttt aaagaagaga
     7021 caggaatgac accttctcaa taccgtaaag gaacttttgt aaaatgagaa aaaaaatcaa
     7081 agagcatgaa ctctttgcca aacttctgtt cattttgttc atcggtcttt ttctgcaagc
     7141 catcgtcatt tctttgttta tttatcatcg atcaagggat gcctatatcc agctgttcaa
     7201 tcaatcgaat gatgtggtac taaaaaagat tcaatctgaa tttgaaagtt tgaatgatac
     7261 aatcgagaat acattagccg cttttgattc taatccagct gtcaaaagct atttttccaa
     7321 tgatccagcc caacatatgg aacagcttca gcaactaaga acaatccaaa aaatgaatga
     7381 ctctctttca aaaatccatc caatgatcga ttacgatgta ttgatctttg gagaaaatgg
     7441 aagaactttt gtcggaaacg acatgctcac tgccgtatct gccgattctt tttttcaatc
     7501 tgcgattgct cagagagtga atgaacgtgc tgctgataca caaatgcttt ttgcacacca
     7561 cggattgact cttcgcgata agaaagcacc cagcgtcttc tttgtcaaaa aactgaaaaa
     7621 tacattgaat cacgtttacg gatatgctgt tttatcgatc tcatccaagc aactagcgaa
     7681 tctttttcaa tctgtagtaa atcctgagat atcgaagatc tccttcatga acgaagaaca
     7741 gacgatcatc gcatcaaatg aagaaaatac aattgggagc cgatcaatga ttttcaaaaa
     7801 actaacagta ggtgaaacaa cgatttcaaa tggacagcag ttgacccgtc ttcctctgta
     7861 ccgccaggat tgtacattac tcagtcaagt cgatcttcat tctttatcta accaaatggg
     7921 cgtgattttt ccgattattt tgtataatat cgtgacactt gcttttgctg gctcattggt
     7981 atttatgtat ttggatcgac acacaaaatc gatctaccgc ttgattgatt cgctaaaacg
     8041 gctagaggaa gatggcttaa aagctactgt tcctgtacaa ggaagccatg aagtccaatt
     8101 gctagggaat acgatcaatc aattgctaag taatgctcag catcattatg aacagacgat
     8161 ccaagacgaa aagaagaaac gttcgcttga aatccaaact atgcaagcac agatacagcc
     8221 ccattttatt tataatacgc tgactagctt gaaatttttg atttggcaga aaaaaacaga
     8281 tgaagcagtt caaggaatcg acagtttcat tactttacta agaagtacga ttgggaaaaa
     8341 agaagaagtg attccagtca aggaagaaat caaaagcgta caaagttaca tcgatctttt
     8401 gagtatgcga tatggcgaaa gaatctcggc taaaataatg attcctgatg aactgcagtc
     8461 attatctatg ccgaatatga tccttcaacc aattatcgaa aacgcctatc ttcatgcttt
     8521 tcacaataaa acgcaaggat tcatcacggt gtacggcaaa acaaaaaatc agcttctttt
     8581 attcgaagtg attgataacg gcgatggctt cgatactgaa aataccaaac aaaaaaatga
     8641 tcatttttca ggaatcggca tcagccatgt agatgagcgg atacgcctaa tgtatggcga
     8701 tgcatatggc ttaacgatcc aatcagtgat tgggacagga acgactgtaa cgatttgtct
     8761 accgcttctt cctaaaaatc aatcagaata tcaaaaataa agaatagcca agcgctgatt
     8821 tttttatttt aagttaaata aatcaatcag tattcttgac tttcatctac gcgtctcttc
     8881 tactgtcagc actggataac agcccaatat ttgactttct cctccgagca tcttgatttc
     8941 ttggagcgca ttctctacta atgtcattgg acggtccaac aacaaatcga tcacgaaaaa
     9001 atattctccc aagctagttt tcaatggtcg ggattcaatc ttacttaagt tgatttcccg
     9061 ccagccaaaa gctgccagca ttttatgaag catccctggc cgattagcag gtagtgtcaa
     9121 gatgacactc atttttactg gagctgactg ctggctggtc atctttcggt caccgacgat
     9181 ccaaaaacgt gtctggttca actcattatc ttggatattc tcagctaaga tctccaatcc
     9241 aacatgctgt gctgtttcta atgaagcaat cgctgctgcg tcttctttcg gatgttctgc
     9301 tacatacatt gctgcagcag ttgttgattc tgttgctact aaaggaacat taggataatg
     9361 cgtttctaaa aactgttgtg attgtgctag tgcttgtgga tgtgaaagga tttttgtaat
     9421 ctttgttgct ggattgccta aaagctgctg cttgatagga agaacgattt cacttttaac
     9481 ttcgacttct ggatgtttgg aaagaagatc gattgtgtga tgaacagctc cttccaatga
     9541 attctctaca ggaacgacag ccagatcgac ttgtttgcga aacaaagcgc gcaaacaaac
     9601 agggatggaa gcatacgcag tcaattgttc tgtaggaaat agctgacaag ccgcctgata
     9661 agtgaatgaa ctttctggcc ctagatagct gacgttcata tgcttttgat cctttctata
     9721 atggtatcga tgatcttttc tggtgtttga ttggtcgtgt tgattcgatg tgtcgcactt
     9781 tcttcatacc aagaaagtcg ttgtgccaat aatgctttta tttcttctct tgtttttcca
     9841 agagctaaag gtcgaataga cgtttcatct tgttggatac gatcaactag acagtccgct
     9901 tctgcctcta agtaaagaac aatcggctgt gtttttaaaa aacgccgatt ttctgcactt
     9961 tggacaatcc ctccaccagt cgcgataatt ttgtcttcat ttgacagctt tcttaaaata
    10021 tctgactcca cttttcgaaa gcttttttca ccgtaatagt gaaaatattc ggcaatcgac
    10081 aattggatat gttcctcaat ctttgtatct aaatctacat actctttttg taaacattga
    10141 gctaaccctt taccgattgt tgtttttcca gcgcccatga aaccaatcag caaaatgcta
    10201 gccatgagct tctcctcctg acacaagttc tgctaaatcg tcaaaaaatg ccggataaga
    10261 gattgaaaca gcttcagctc cttctagttc gcaaggtcca tcagctatca aagcagctac
    10321 ttgcagcatc ataccgattc gatgatcgcc tctgctggac acttttgcgc catgcagagg
    10381 tgtcggccca tggatgatca gaccgtctgc tgtcgctttt atctttgctc ccattttctg
    10441 taattcttct gccaccgcat caattctgtt ggtttctttt acttttaatt cttctgcgtc
    10501 tttgatgatc gtgattcctt ctgcttgagt agccactaaa gctagaatgg gcaattcatc
    10561 aatcagacgc ggaatgattt ctccaccaat cgttgctttc ttcaaatgac tcgtcttgac
    10621 acttaaatca gccgattggt tctgttcatt gtgattcgtc tgggtaatcg ctgcgcccat
    10681 ctcctccaac acatctaaga taccagttct tgttggattg accccgacat tttttaacaa
    10741 cagttggctt tccggaacaa gaagtcctgc tgctagaaag aaagcagctg atgaaatatc
    10801 acctggaaca gttatctgtt gaccagttaa tttttgcggt ccggtcacta tgatcgtttt
    10861 atcttccact gtgatccttc cgccaaattg acgaatcatt tcttccgtat ggttacggga
    10921 acgttctttt tcaacgatta cggatgtgcc ttctgcttgt aatgccgcaa acagcaaagc
    10981 agatttgact tgcgcactgg ctacaggcat attgtatcgg ataggtgata aagagcgggt
    11041 tcctgtcaca gtgattggta gatactggtc attttcttct ccttgcaagt cagcgctcat
    11101 ctcgcgtaaa ggttccatca ctcgccccat tggacgttta gacaacgaag catccccgaa
    11161 cagagtagtc gtaaaaggct gtccagccaa aatacccatc aataaacgta tggtcgtacc
    11221 ggagtttccc atgtcaattg attcggttgg ttggacaaat gagtggctac cgcgaccatg
    11281 aatcttgatc acctcttcct cttcttcgat ctcgacacct aattgttgga aggcatgtaa
    11341 agtactcaga caatcttctg cgcgcaaaaa attttgtata gtcgtcgttc cttcagcaat
    11401 tgctccaaac atgatgctgc gatgggaaat tgatttatct gctggtatcc taacagtccc
    11461 tcttaatcca tgtatttgtt gtaataattg catttatcca gcctcctatt tgatccagca
    11521 atgataactg gtattagaca taatgattct ttttgcttgt aacaaatcct gttggttttt
    11581 aaaactgatt tgcagtattc ctaaaatatc ttccctggtc tcttggatct tcaaattaat
    11641 caaagaaact cccgcttttc cgatcagtcc agttacttct gcaataacgc caggttcatc
    11701 tggcacatcg ataaataaat caaaaaaggc aggaatcgcg ccttgcttat ggacaggcaa
    11761 ctggtctcga ctttcttttg cccgattgaa aaaagaaaag atttccgatt ggttctcagt
    11821 catgatccat tctgctattt gtgtcatttc ttgttgccaa tctgccaatc gttccaataa
    11881 tatctgctta ttgctcaaca aaatatctgt ccacatgaca ggatctgagg aagcgatcct
    11941 agtgatatct cgaaagcctc ctgctgccag ttgtttggct cgcggatact cttgattgaa
    12001 ttgttctgcc tgattgacta agccagctgc cagaatatgt ggaaaatgac ttagcattcc
    12061 tgttatacgg tcatgttctc ttgctgtaag agttacatat tttgctttgg ttccgcaaaa
    12121 tagttcttgc agtttttcaa catctttttt cgtcttttcc aaaggtgtaa agatgtaata
    12181 ggcattttca aatagtttag catctgctgc ctgtatacct gatttatgag aaccagccat
    12241 tggatgtcca ccgacaaacc gaagattttt ctgctcagcg gatgtcacga cttgctgctt
    12301 cgtactgctg acatccgtaa tgatgacgtg atcagacaag ttgattcttt caaggacatc
    12361 aagataagct aaggttgtac ggacgggaac ggctaataag ataacgtctg cttgttctgc
    12421 acctgtttca aaatcacttg caacgtaatc aacgatctgc tgttctactg cttgctcacg
    12481 ggtttttgac tgactatccc aaccaactac tatcagttct ggattggtct gacgaataca
    12541 aagtgccata gaagcaccaa tcagtccaag ccccacgata aaaacatgtt gtgccatctt
    12601 atttgccccc tttttagtaa tgtttcaagt agtcacggta ctccttcact gcagctttca
    12661 actcaacaag cgaatcactt gggaattttg acaatagctc tgtcgctacc acagtggcta
    12721 caacattttc cgcaacgacg ctagctgcag gaactgctgt actatccgaa cgttctacac
    12781 ttgctttgta aggttctttt gtatcgatat caacactttg aagtggcttg tacaatgtag
    12841 gaatgggttt catgaccccg cgaatgacaa gtggttcgcc attggtcatt ccgccttcga
    12901 agccgcctag attattggta cgtcggaaat agcctctttc ttcttcccat aggatctcat
    12961 ccatcacttc tgagcctggt aatgaaccag aagtgaatcc gaccccaaat tctacgcctt
    13021 taaaggcatt gatactaacc acagcttgtg cgattttggc atctagcttc gtgtcccatt
    13081 gtacgtagct tcctaatcca gctggaacgc ctccaacgag cacttctaca attcctccga
    13141 tcgtatctcc atttttcttt gtctgatcga tcaaatcttt tattctttgc tcaactgctg
    13201 gatcaacaac tcgtacttct gacgcttcag aaatttcttt gatttcttga atcgagatat
    13261 ttccaggtat ttctgcttgg attccaccaa gacaaatcac gtgtcctgct acgatgatgt
    13321 caagttcttc cagaattttc ttggcaattg cgccgattgc tacacgcatg gtcgtctctc
    13381 ttgcagagga ccgttcaagc acattccgaa gatctcgatg atggtatttc ataccgccta
    13441 ccaaatccgc gtgtcctgga cgcggacgtg caactcgccg cagtgattgg tctttttcag
    13501 gcacttctgc tacagacatg acagttgtcc aatttttcca atctttattt tctaccacta
    13561 aagtgacagg tgaaccaatt gttttgccgt gacggatgcc agacgtgatc cgaacacgat
    13621 ctttttcgat cttcatcctt cctcctctgc cgtaaccagc ttgtctgcga gcgagttcgt
    13681 gattgatttc ttcttctgac agaggtaatc ctgctggtag tccttcaata atggctgtta
    13741 attctggtcc atgggattct cccgcagtca tataacgcat cttacagtcc tcctaagtaa
    13801 tctttgaatg tctctgtggg aacaggaacg atttttgctt gcccaatctt ttctagcaag
    13861 atgatattca attggcttcc tcttgctttc ttatcatggg ttatcgcgtg gaataattca
    13921 tctggatgac ttagatcgta cgtaatcggc agatggaatt tttgaagtat cctttctaaa
    13981 gcagctgtcg atccagttgg agacaagccg attttttctg catgagaagt gatggctacc
    14041 attccaatag ctactccttc tccatgactg actaccccat atcctgctgt attttcaatt
    14101 gcatggccaa ttgtatgacc aaaatttaaa ataagtcgat ttccttggtc aaagacatct
    14161 tcttccacta cttttcgttt gatttccaac gtagcagtaa tgattggaac agcatgttcc
    14221 agaagatctt tttcgtcttt cagctcgttc agctgtttcc aaagcgttgc atctgctata
    14281 gctgctgatt tgatgatttc agcgattcct tctcgtaaac gacgtaccgg caaagttttt
    14341 agaacctcag gatcaatcaa tacaccagct ggctggctaa atgttccgac aaggtttttc
    14401 gctttgtttg tattgactgc tgtcttcccg ccaatactag aatctacttg tgcaagtagc
    14461 gtagtcggaa tttgaacgaa atggatccca cgcatgaacg tcgaggccac gaatgctgct
    14521 agatcaccca ccattcctcc accaagtgca agtatcccat cgctgcgggt aaaatcatta
    14581 tctgctaaaa aatcgtataa ctcagctgct tgttctaaag atttactggt ctcacccgcc
    14641 ggtacgattg aaaggactgg ttcaaaatta gcttgtctca attggaacat gattttttct
    14701 gcatatagtg gagcaacgtt tgtatcagtg atcacagcta ctttttgagg tctccaaatc
    14761 gtttgaagcc atgatccagc ctgttctagt gcgccttttt caatatgaat atcgtatttt
    14821 tggttatcaa catgtacagt aagcattcgt ttcacttctt tcttttaaaa agctggaatt
    14881 aatcgagtgt ctgaatcttt tccattgctt ctttcatgat cgcaacttct ttcatcatgc
    14941 gtgagtaagt cttttcattc aacgattggg gaccgtctga ccaagcattt gcaggatcag
    15001 gatggatctc tacgatcatg ccatctgctc cgcttgccac acccgcacga gccattggtg
    15061 gtacaagttc ccaaattcct gtaccatgac ttggatcaac aatcacaggg aaatgagtta
    15121 attttttcat caatgggaca gcacttaaat caaacgtatt acgtgtcgct gtttcgtaag
    15181 tccgaatccc acgttcgata aaaatgacag gagatttgtc ttcgactgca atgtattctg
    15241 cagcattaag ccattcattg atcgtaccgg aaattccacg tttcaatcca acaggtttac
    15301 ctgttttacc gacagcagat agcagtttaa aattttgcat attacgtgcg ccaatctgta
    15361 ggatatcgct gtactcagcc accatatcga tatgcccttc atccatcact tcagtaatca
    15421 ctttcattcc aaattcatca gccgcttgac ggatgtattt caatccttct tcttctaaac
    15481 cttggaaagc atatggagaa gtacgtggtt tgaaggcacc acctcgcaga atttttgcgc
    15541 ccccggcttt ggccattcgc gcacattctc tgatttggtc taatccttcg atagaacaag
    15601 gaccagccat cgtcacgaaa ctgccgtcac caatttttac tccgtctaca tccacgactg
    15661 tattgccagg atggaattct cgagaagtca atttgtatgt gtttaaaata cgcacagcat
    15721 tttctactcc ttcatagcgt gtaaatgctc cttcttgtaa acttcgcgta tcacctttta
    15781 gtccaatcac tactcgttct gttccttgat cgattgagac tttgaatcct tctttttcga
    15841 tatgatcgac gacttttttt atttgttctt ccgttgcttc ttttttcata attactatca
    15901 ttgtttttcc cgctttcttt tgtttactta tctatcttgg ctgattttct ctactttttc
    15961 aaggtggttt tacattaatt cctactaaat gaccgtgtcc tgttgttctc attttcgctc
    16021 cttctttcct acttatgacc cagataatca acaaaaaaag atgtccctgt aggaaattgc
    16081 ctctacagtg aacatcttca acgagcctta aaaagcgctg caaaaatata aaatagccac
    16141 tatagatgaa tttctctacg tggctgtaag tcgtgtttaa aaatctttag ccatcataga
    16201 tacaaacctg gtttgtttgt acccacgaag tcatgaatac aaacctatct aaaatagcta
    16261 aagtaatacg tattcagttt tgtaagtttt ctagatttca taaaaaatcg ctccaaactg
    16321 atgtaagaat tgtacctagt atagacataa aaaaatcgac tgtcaatcat ttttatgaaa
    16381 ctttttttaa ttttctgata gttaactttg tttttcagaa aaataacaat tggttttatt
    16441 gaagaaaata gtcatgaaca aaagtatctg agaacttttt tactctcttg ttcatgacat
    16501 atagaataaa gcagctttgt cttgtaaact ccgtttttca aataataatc taaagattgc
    16561 tactgaataa taaagccgat ttcatggtcc tcttcgctgc tgattcggta aggtgactca
    16621 acatccgctc cccagctatt gatacccccg actcctctta cttttgcaaa aatcgtaaga
    16681 accgttcgtc tttctggcgg tagttcttct atatgtgttg cctgttccag ttcttctgct
    16741 ttgaatggta aagcggaaaa agcaaatggc gtatcctgct gttcaaatcg caacgaaaaa
    16801 tcttcttgat ctttatccgt attatccaac gtttgatttc ttgttagttc tacccatttc
    16861 gtttccatat gcatgccgca ttcttgggga acaaggtatg gggaaacggg gagtcctgcc
    16921 actttataaa taccttcgac accaccagcc atccgatccg gatatgtttc ccctgatagg
    16981 ccttcatact caaaaaattt tgctttcgtt ggcataatga accttaaacc caatgcgggt
    17041 aattccggta atcctttttg tccataataa tgcatattga caagcatttt accctctcca
    17101 gcgatttggt aggaaattgt cacttgggtt tttggtactg tgttgatttc cagtgtaaaa
    17161 atgatttcaa ccgtttcagc gtattcatta cttgaatatt gattatttac tggagcaatc
    17221 ggcaaatcga tctttttatt gtccaccagt acttctattt ctttgacttt tggatacaat
    17281 ccggctccta accacatacc ggatttaaat ccaaatccgc tacctctgtc attatcggtc
    17341 gttgctcgcc aaaaaactgg aagtgtttcc cggtatagcc attcttttcc gtttttattg
    17401 agcgattcca gtccgcctct tgtataagaa aaaatataat gcgtattccc cgatttgaca
    17461 cctaatgtac agtcgccgaa gacgattgca actttttccg tatccatatg acttttattt
    17521 actgtatttt tcataataat atcttacctc ctgcatggcg ggtttttctt gtccatctgc
    17581 aaaaacgatc ccattccctg agaattcata gtcacttggt ttatcgtcaa agtcaccgcc
    17641 atagcgcatc acttctctgc ctgtgattgg atcagtcact tggatcgcct gatctttaaa
    17701 atcccatata tagcctcctt ggtacatttc ataacgatca agcaacgtca tgtaagaatc
    17761 cattccacct aacgaattcc ccatgtcatg catatattca cataagatga acggtttttc
    17821 cgctttattt tcaaggtagt caatgatctc ttctggtggc gcatacatgc agctttttat
    17881 atctgaaatc gaatcttcga atgctggatt tggaaaattc ccttcataat ggacaagtcg
    17941 atcggggtct acttttttga agtaatcgtt catttgtcga atgttttctt ccgcataaga
    18001 ttcatttcca agagaccaaa aaagaatact tggatggttt tttaatgttt cgaaattcgt
    18061 ttttgctcga tcaagaacag ccgcctgcca ctgaggtact gcacctggta cgttgtaaga
    18121 aggctcaaat gcgcccattt tttgccatga gccatgggat tcgaggttcg tttccgccat
    18181 cacatggatt cctgcttggt cgcataaata ataccaagtg atctggttgg ggtaatgaga
    18241 tgtccgtacg ccgttgatct ttgcattttt tatgatagcc aaatcttttt ccatatcttc
    18301 tatagtgatg gcgcgtcctt ttttcggatg ccactcatgt cgatttaccc cgttgataat
    18361 catccgtttt ccattgaagt agatgatttt atctttgatt tcgattttac gaaaaccgaa
    18421 ggaatagtca atatactccg ttactctttt ttcttcgtct atcgtctcca attcaagctt
    18481 atataaattg ggctgaaaat gcccccacag tgccacattt tcaaatccat cgatgcgaat
    18541 cgtcatttgc tcttttaacg gatattgctg ttgatagatt tccttcccat caggatctag
    18601 tatcgctaca ttcagctgac tgtttttggc tacttgctca aaagacaaat ctacttcaag
    18661 tttgccattt tgacatttgt catctaagcg aggtttgatc caaagatctt ctaaatggtt
    18721 ttgtcctcga gcaactaaga agacatctct gaagatccca aaaaatcgga aaaagtcctg
    18781 atcttccaag aatgcagctg tacttctttt gtaaacctcc acagctagaa tattttcttc
    18841 ttccaaataa ggtgttaaat caaattcaga cggagtgaac gaatcttcgg catacccgat
    18901 aaaatgacca ttcaaccaaa taaacattgc ttgttctaca ccagcaaaat gaatcgagat
    18961 ttgttttccc tttagacctt cttctaatcg aaaagtcgtc aaatacgaac caaccggatt
    19021 gtctttagca gctgaaaaga tcccttccgc ctctttctca gggcttgtcg tgaaaggggg
    19081 acggcgaaat acatgtccct cccacggata catcgtattg atgtaatgga tcttgtcata
    19141 atttgctaat tcaatatgac taggaacagt gatttcatca aaagaacagg catcaaaatc
    19201 ttttttataa aatgtttttg gtcgtaccga aggatttggc gaataacaaa aacgccatga
    19261 tccatttaaa gactgtttaa gggaggatgt ggtttctact tcttcccttg ttgcataaca
    19321 aacatgatcg ctatgtgcat ttgattggtt cactctaaaa acttgtggat catctaacca
    19381 ttttatattt gctttcatac ttttttcctt ctctctcata actttttgaa atgaagcagt
    19441 tctgtttgga aatcaccttg aaaatcgggg aagtaaagtc caactgtcat caattcggcc
    19501 cccgaaaata tccgcttcga ggtctgttcc tgataaagtg cctcatcatc taaccccatc
    19561 agatatactt catggaacgc tggttgagct gaagctagta tcctccctaa aaacacaata
    19621 gcttcatctt gtttaggaga cacaaacatc catgcggcaa tattttcttc aaaaggactc
    19681 gccaaacgat aataatggcc atactggatc accggacgaa tcgtttgata ggatataatt
    19741 tggtctttta cttgcttttt ttcttcagga gacagctttg tcaaatccag ttcataacca
    19801 aaaacagcgc tcatagctgt ttctcctctt gttttcaacg aagtagatct gtcggtctga
    19861 tgatttggta cagctgatac atgagctgtg atggacgaaa tcggataagc aaggcttgtt
    19921 ccatattgga ttttcatacg ctccactgca tccgtgttat cacttgtcca tgactgcggc
    19981 atataataaa taaacccggc atcaaaccgt ccacctccac cagaacagcc ttcccataag
    20041 atttccggat aatcagttgt caaatgttca agtagttcat aaagcccgag catataacga
    20101 tgcgctactt ctccttgtct ctgtgggtca agggtaatcg aatagacatc tgaaagcgaa
    20161 cggttcatat cccatttgat gtagtcaaga ggaatcgtat ctaaaatctt tctcatttgt
    20221 ttctcaatcg tctgccgaac atctaacctt gtaaaatcca gtacatgttg tgatctggaa
    20281 gcagaaggca ttctacctgg ctcctgcata agaaaatcag gatgtgttcg atacagttca
    20341 gaatcaaccg agatcatttc aggttcaaac cataaaccaa atttcaatcc tttgctatga
    20401 gcataatctg ctatttcacg taatccattt gtcaacttgc cttcatactc gaaccagtct
    20461 cctaatgaag aattgtccgc atctcttttt ccaaaccagc catcatctaa tacgaacatt
    20521 tcgatgccta gctcctttgc ttcatcaatg atcgccttga ttttttcact attgaagtca
    20581 aagtaagtgg cttcccagtt attgaccaga atcggccgtt cagcaaattg atgacgacct
    20641 cttgcgattc tttcacgtag caactcatgg tggatctgac tcattttgtt caatccctga
    20701 cttgagtaag aaaggatcat ttcaggtgtt tgaaaagact ggcctgcatt caattcccac
    20761 gaaaaacgat ggctgttgat cccaccgacg actctcaatt gattgatctg atctttttca
    20821 agttcgaaag aatggttgcc ggaataaaca aattgaagtc cgatcgcttc tccagtattt
    20881 tctgtcgtat gatgatgaac taaagcaata aagttattca tatggtgact gctcgttcct
    20941 cgacggcttt caaatacttt tgttccagat aaaacagatt gccgtgaaat ctgtctttca
    21001 ttgacatgtg ctcctggcaa agcaatgact tcatcaaatc gcctagtatg ggcaaagtct
    21061 agctggaaac tagccgcttt ttctagtttg attgtttctc cggtttcatt tcttatcttt
    21121 acagatcgtg tgatcactgc tctatcagta aatatggtat agaacaaatc gaaataaatc
    21181 gctgtttctc tatccttaag tgaaatcacc aacgtttgtg cctctgactt gtccatcaca
    21241 taagtttgag gcaagccttc gatctctggc ttcccatctg taatataatg gctgtcatat
    21301 ctcagatcca gtaagtctga tccattcttg cgctgaatga tcgatgcggg cgttcgaaag
    21361 tccatgctgc catgagaaga gtattcttgc ggtagtgtat ctttcgacag agaccggtca
    21421 ggatttaagg gaacatttcc tgaaaatcca cgatctcttc ggggataatt tttattgtct
    21481 ttgtactgct tgactggttt gccaaaataa atatgcgcca atacattgct ttcttctatc
    21541 tttatcagat aagaaagaaa tgtatttcgt aaatggaaga ctcggctctt ttcatcaaat
    21601 aagatgaaat ttttatctgt ttttctatgc gtaatatcca tcatttcact cccaacaaaa
    21661 cggaaaccgt ttactttttt ttataattcc tgtatactgt ttactaaaca attttgtcaa
    21721 taaaaatttt ttattttttt gaggagtgtg taaaaatggt tggaattaga gatgtcgcac
    21781 gaaaggcaaa tgtctctcct gctacagttt cccgtgtgtt gaataacgat cagacgatcc
    21841 atgtggctca gactactcgg caacggatag tagaggcagc tgctgcgttg gattatgaca
    21901 tcagtactcg taaatatatc aaaaagagaa tgccttcgat tggtgtgatc tctacgatcg
    21961 gcaaagcgag cgaagaacag gatatctatt acaaacattt gcgagtaggg atggaagaag
    22021 aagctcgacg tctgcattta gggatgaatc gaatctataa tctatctgat aatcctaaac
    22081 aatgggaaga tctagatcag ttaggtgcgg tgatcgttgt tgggactgtt acgaaagaat
    22141 cgattaccgc cttgttaaaa caaaacatgc aaatagtcgt cgtggataac cctgacatcc
    22201 agcaagaggt cgatatggtg tatgcagatc ttgaacggat gactaaaacc gtactggaat
    22261 tgttcttaga aaatggtcat aaaagaatag cctatatcgg gggatataaa gtcgatatgg
    22321 atgaattcgg tgggaagcag atttctataa atgaaaagag gatgcgtgcc tatcagcatt
    22381 ttatgatcga tcatcactta gaaaaatata tgtcttatca tctaggtggc tggacagaaa
    22441 aacaaggtga ggtacttgcg actaatctat tagaaaatga atcccctctt cctactgcca
    22501 ttcttgtcgg gagcgatcca atggcaattg gtgtctatcg ggcattgaaa caaaaaaata
    22561 tccaaattgg agaagagatt gttgtagcaa gctttgataa tatcgagaca atcgcaaacc
    22621 tctcccctgg cttgaccagt gttcaaatca atgcgaaatc aattgggcaa gcagctgttc
    22681 gaatggcatt ggagcgaatt gacggtatac gggacgaacc aatcattttg acttatcctg
    22741 cacgattgat tgttagggaa agttttatcc caagaacaaa aaggtattga aagagaggtt
    22801 gtgaaaagcc gcttcgtttc ttcatactca aaacgaaacg gctttttcac aacctcttac
    22861 ttatacttat tcacaaaatc caatgtctgc tggtaacaat tttgcgattc ttttagcgtg
    22921 taatcaaatt ggtattcatg ggtaatctct ttttttgtat ctgtataaaa caaggattgc
    22981 acgggtacct ttaattctgt caaccgattt tctaatgctt gaccttgctc ctggaatgag
    23041 tatgcatttc cgtcagttat atacgttggc ggaaattcct tagaaacatg gtcagccaca
    23101 ctagcttctt tcaattgctc actcgttttc caatcttttg ttccaatcaa cgaccacgca
    23161 acggttttga cgaaaaactt cataaatcga tcatccgaat gctgctgtgc tgttagcttc
    23221 aaatcaacag gtccgcaata agaaatggtt cctttcagac tatcttttgg aagtagctgt
    23281 ttgattttca tttgtttagc atacgcatca ttcgtttgta tagctgcata ttgcaatgcg
    23341 atttgtgaac ctgcactatc tccaccaaaa aataattgtt ccatgtctag caatttgtcg
    23401 tctttttctt cagctaataa atctttgatc agttcattca cttgaagaac ttgattaggg
    23461 tattctgaat caggcgctaa ttcataattc atcgcaacca ctgcgatgtt ggcgtctgaa
    23521 actaattttg tcgcaaattc tttgacaccc gatttatctc cgccgacgaa tcctccacca
    23581 tgtacccaaa atagaacagg aacaggcccc ttgctgtttt ttggatagta gatgtcataa
    23641 gtattctctt tatacttgga ctcatacgtc aaatctgttt ttttcgccac gtttttttct
    23701 gcttgatcga acgttttttt atcagtgatt tgaacagtat ttgaaaacat atggttgatc
    23761 aagaatgctc caggtctggg ggaaagctgg aaggcaagaa agattgcaaa cgcgatccca
    23821 agaatgattc cgaagaacca tccgataaat ttaagaattt tctttttcat aaggctccct
    23881 cagtagttag tattaagcat tctgattata ccatagtgtt atttcctatc aagctctcct
    23941 agatgattta atgattttcc ccaaacttct tctgcaatgc ttttgacaaa agaaattttt
    24001 tccattgttc ttcaaacaaa acattttctt cttctgttga agcaaatcca cattgaggac
    24061 ttaagcacaa acgatccaaa ggcagatatc gtgtcgcttc gtagatccgg tcaatcactt
    24121 gctggtgctc ttccatttcg ccatttttcg ttacagtcaa aatctaagac aactaattta
    24181 tcttcagaga ctttctctaa aagaacaaaa ctcccagcac gttcactatc gtattctaaa
    24241 taataggcac ggacattttc ttgagtaaaa taatgggtct gctacgtcgt catcccccct
    24301 gatgccgcca aaatcgaata ataatttccg cgtcaaacat gtatatttag tgttgaatca
    24361 tttgagaata tgaaaataaa aatctttttg atcaatcagt taatcaaatt gaaataacga
    24421 aaaatctgag acagaatgac gttcattctg acccagattt gattttgcac aactcaacag
    24481 tccttattgg caaatcgcca aaataatgta gactaactaa aaagactaag aaacaataac
    24541 aaaagttaac acttcttagt ctttctttag cacgtctatt tattaaagat tttagggcct
    24601 tttctcatgt ttttacgatc attcttaggt gtttccattt gtttggatcg gcctccacct
    24661 tgtttctttt tgatcaattc tttcattttt tctttttggt ccatttttat tctcctttaa
    24721 cgaatgaagc gactaattcg atatgatggg tttgcgggaa aagatctaca ggctgaactt
    24781 tcttcacggc ataacctgct tctgcaaata acttagcatc tcttgcaaaa gttgccggat
    24841 tacatgagat atagacgatt cgttctggtg acatttcgat tgctgattca ataaaatgat
    24901 gatctaatcc ttttcgtgga gggtcaacta cgatcacaga tggtttgatc cctttttctt
    24961 gccatttttt cataactttt tctgcttttc cgacttcata atgaacattt tcgattttat
    25021 tatttaaagc attgaactgt gcatcttcaa ttgcttctgg aataacttcc atcccataca
    25081 ccttatccac tctgtctgct aaagacaagc caatcgtacc tattcctgaa taagcgtcga
    25141 tcacaatgtc ttttttatct aactcggcaa actcgatggc tgtttggtac agatactctg
    25201 cttgttgagt atttacttga taaaatgact ttgctgagat tcgataggtt tttcctaata
    25261 gctgatcttc gatatagtct ctgccatata aaactttttc tttgtctcct aaaatcacat
    25321 ttgttttttc ttcattgata ttttggatga ccgaaaccac ttctggcaat tcttcatgaa
    25381 tagcttcagc aatttccttg gatttaaaga atttttcttt acgagtaact aaaacgacca
    25441 tcatttcatg ggaataatga ccacgacgga taatgatgtg acgaagctgt ccttcatttt
    25501 tttcttcatt atatcctcgt acttggaacc gttgcaagat atctctgact actttgattg
    25561 cttgatcgat gacaggatct tggatataaa aatcttcgat agggactaga tcatggctat
    25621 tctttttgta aaaaccggtg gctaactgtc catcgatacg gcgaacaggg atctgtgctt
    25681 tattacggta gccgaatggt tctgccattc cgaccgttgg aagtacagga acttctggca
    25741 tcttagcaat cttcgccatt acatgctcta cttgtttttg tttgaagaca agctgttgtt
    25801 catacttcaa atgggctaaa ggtgcgatac ctatgcgaag taatgcattg ttttctacag
    25861 gctgacgatc aggtgattgt gtaataaatg tttcgacttt tccatatcca aacttattgc
    25921 ctgcttttac tactagtatt tctacttctt ctccagggag tgcattttcg ataaataatg
    25981 gataaccatc gatttttgct acccccattc cttcataact caagtcgacg atttcgactg
    26041 tatatcgttc gtttttcttt actatttgct gttctgtcat attttgctcc tttaagccta
    26101 tttttcaatc ctactgaact ctactataaa tcagctaatt acacaactaa aaccggcact
    26161 gaccttacta cgttcagcac cggcttttga ttaattcttt tgattaggtg tttcgtctgc
    26221 tatttttccg tcaccgtcga tatcttcatc cgttaaacgt tcgacttctt ttacgaattc
    26281 tttgctgaca acctctaatt cttcttcatc tgtacctgtg attgcttcat caggaatctg
    26341 atcggtattg gcaaagaact caatgtgttg atgaagattt tggaaatgca tcggtgcttc
    26401 cccgccgtat tcaccatcta agttgatcat tactggtcga ttgatatcat cttctgtttc
    26461 aacgaacaaa ctgcttgttt tggtatagat tattcttgga tcatcgacat gtcgaccgcc
    26521 attcagcatg agtgctgcaa tatgcaagat ctcaaagata tttgctgtct tcacaatgat
    26581 taaagaaaac ttcccatcat ccaatttggc atctggcgcg atctgttcga atcctccaac
    26641 agagttcgtc agccctagga aaaacatcga agcatttccg atatattccc cttcatcata
    26701 cttcaagcgc attttgattg gctttactcg agggagcatc tctgctcctt tcgcaagata
    26761 agcaagataa ccaaaaatac tctttagttc tgatggaact tcataagtca attctgtcaa
    26821 atagccacct gcagcgatat tgatgaagta actgttatca gaaaggccga tgtccatttt
    26881 tacggtttgg tgttttttta tcacttctgc tgctgcttta atattatctc taggaatttt
    26941 taatgctcga gcatagtcgt tcgttgtacc agctgggatg atggccattt taggacggtg
    27001 ttcaagcgga gcgattccat taaccacttc gttgattgtg ccatcgccac cagctgccac
    27061 tactagatca aaacctagtt ctgcgactct acatgcttca ttcttggctg aatctggttc
    27121 tggtgtagtt gcataggcgc tggcttcaaa tcctgcttct tctaatgcct gtaggatatc
    27181 cgccaaattt tttttcaata attcttttcc cgaggtgggg ttataaatta cgcgtgcttt
    27241 tttcattttc agcctctatc gtttcgctaa ttcatcttta agtagcttat tcacgacacc
    27301 aggatttgct tgtcctttag ttgctttcat gatttgaccg actaggaagc caaccgcacg
    27361 atcttttcca tttttgaaat catcgacaga ttgttggttg ttatccaaaa tttcattaat
    27421 gattggcagt agtttgttcg gatcagataa ttgcacccaa ccattttttt caactacttc
    27481 ttgggcttct ccgccatttg tgatcaattc acggaagact tttttggcga tttttgagct
    27541 gatcgttcca tcggcgatca aacgaatcat tcctgctaag ttctcaggtg tcaattttgt
    27601 ctcagctaat tccagtttct cactgttcaa gtaagcagaa acttcaccca tcaaccagtt
    27661 agatgcttgc ttggcatctg caccattttc caaaacagct tcaaaaaaat cagacatttc
    27721 ttttgtaagt gtcaatacca ttgcgtcata ctctggaagt ccaaactcac ggatatagcg
    27781 ttcgcgacga gaagctggca tctcaggcaa actagctttt actttttgaa tccattcgtc
    27841 atcgatcacg aatttcggga tatcaggctc tgggaagtaa cgataatcac tagacccttc
    27901 tttgacacgc atcaaaactg ttttattcgt tgtttcgtca aaacggcgtg tttcttgttg
    27961 gatttctcct cctgaaagaa gaacttttgc ttgacgtttt tcttcaaaag ctaaaccttt
    28021 tttcacgaaa gataaagagt tcaagttttt caattctgct ttcgtaccga actcttcttg
    28081 tccataaggg cgaagagaaa tattggcatc acagcgcata gagccttctt ccattttcac
    28141 atcgctgact tctgtaaatt ggataattga tcgcaatgct tctagataag cgtatgcttc
    28201 ttctggtgaa cgcatatcag cttcagaaac gatttcgatc aaaggcgtgc cttgtcggtt
    28261 caaatcaacg taagaataac cgccaatacc atgcatgttt tttccagcat cttcttctaa
    28321 atggacacgt tcgatccgga tttttttctt tttaccttct acttcgattt cgatccatcc
    28381 gtcatgaccg attggttgat caaattggga aatttgatat gcttttggat tatctgggta
    28441 aaagtaattt ttccggtcaa aatgagtatc tttagagatt tcacagttta atgccaaagc
    28501 tgctttcatc ccgaattcca gcgcagcttt attcattact ggcagcacgc ctggataacc
    28561 ccagtcgatc acgtttgtat tgctgtttgg ttctgcacca aaatgagctg gcgctggaga
    28621 gaaaattttt gagttggttt ttaactcgac gtggacttct agtccaatga ctgtttcaaa
    28681 attcattcgt ctttccctcc taaaatagct ggttgttgtt tatggaattc tgttgcttgt
    28741 tcaaacgcat atgccgcttg atacatcgtt ttttcatcaa aataattacc gatgatctgc
    28801 aatccaactg gtaatccttc tgataaacct gccggtacag acatacctgg aagtccagcc
    28861 aagttgacag ggatcgttaa gatgtcactc atgtacattg tgattggatc gttaatgttc
    28921 tcaccgattc cgaatgcaac tgttggtgaa gatggcccga tgatcaagtc ataatctgca
    28981 aagacttttt caaaatctcg tttgatcaat gtacggactt gtcctgcttt tttgaagtaa
    29041 gcgtcataat aacccgcgct taaggagaat gtacctaaca tgatacggcg ttttacttct
    29101 tcaccgaatc cttctgaacg tgagttgaca tatacatcat ctaatgattt cacattttca
    29161 gagcgataac cgtagcggat accatcgaat cgttgcaaat tggaacttgc ttctgatgag
    29221 gcaatgatat aataaacagc cacaccgtat tttgaatgag gcaagctgac ttcttccaca
    29281 acagcaccta atgaacggaa tgtttctgct gctttcaata cagcttcttt tacgccaggg
    29341 gccacacctt cgcctaagta ttctttaggt aaagcaatct tcattccttt gatgtcgcct
    29401 gtcagtccct ctgcaaaatc aggaactgaa acgcctgaag aagtaccgtc tttttcgtca
    29461 taaccgctga tagctgtcaa tgctaatgca ttatctttca ccgtacgggt cattggtccg
    29521 atttggtcaa gagatgaagc aaaggcaatc aaaccaaaac gtgagacacg gccataagta
    29581 ggtttcatcc ctacgatgcc gttaaaagct gctggttggc ggatacttcc cccagtatca
    29641 ctacctaaag aaactggaat ttgtccagct gcaactgctg ctgcagaacc accagaagag
    29701 ccaccaggta cttttgttgg gtcccaagca ttttttgttt tcttgaaata agaagtttct
    29761 gtacttccac ccatagcaaa ttcatccatg tttagcttac caacagggat catatctgct
    29821 tgatagattt tatccatgac cgttgcatca taaattggtt caaaattgta aaggatctta
    29881 gatgcagcgg ttgtcaagat atcttttgtt acgatattat ccttgatacc aattggaata
    29941 ccagcaagga cgttgctttc atcaatccct ttttcatcta aagcttttgc ctgttccaat
    30001 gctttttctt cgttcaatgt aatgaatgcc tcgacctcag gctctgtttc tttgattcgt
    30061 tcaaatgttg tttttgtcaa atcttgtaca gtgatttctt tcgatacaag catatgatgc
    30121 agttcttcta gagaacgatt gtgtaattct gtcattatgc gccagcctcc ccattatcga
    30181 tgattgcggg tactttgata aagccgtctt ctgtttccgg cacatttttc aataattcat
    30241 cgcggttcca tccagcttgc gcccgatctt gtcgcatcac gtttactgtt tcaaccacat
    30301 tcgacgtaaa tggaacacct tccgtatcta cttcttccag catttcaacc atatcgatga
    30361 ttttacctaa ttggtcggta aaacttgcaa gttcttcatc tgcgaacgca agttttgcta
    30421 atttggcaac gtgtttcact tgttcttcac taatcgccat actacccctt ctttctaaac
    30481 gagttaaaaa ctttgctctc tattttaaca caagagtgcc gtgtctgaaa ttgtttattg
    30541 aaatttgtct gaaaaaactc atttttcatt cttctactga gcgactttta gccaatgcat
    30601 ctgccatttg atcttctgtc caaacttcga ttcctaattc ttgtgctttg gtcagcttgc
    30661 tgccagcatc ttctcctgct accacgatat ccgttttttt cgatacgcta ccagtcactt
    30721 tcccgccaag attttcgatc gtctcttttg cttcttcacg agtaaatcgt gttagtttac
    30781 cagtaaggac tactgttttt tctttaaaag gagactcgac ttcttgcaat tgggcatttc
    30841 gaagcccttt gtattcgaaa ttgacgcctg cttgttttaa ttcattcatc aattcatgga
    30901 cttcttcgtt actgaaataa gtgactacac tgtcggcaat gatatcaccg atcgtatcaa
    30961 gcgcaataat cgactcatag tcacttttac tcaatgtttc tagatcaccg aaatgttctg
    31021 ctaaaatttt tgctgctttc gctccgacat gtcggattcc taacccgaaa atcaaccgct
    31081 cgaccgaatt atctttgctg ttgtcgattg ctgtcaaaat attatttgct gatttttctt
    31141 ttattttgtc caacgtcaat aactcttctt ctgtcaattt gtaaagatca gcaacatctg
    31201 ctactagttt tttatcatac atctgttcta gtacgcgcgg ccccaaccca tcgatattca
    31261 tcgcatttct tgaaacaaag tggttcaaac cttctttcat ttgagcaggg catttaggat
    31321 tgatgcaccg taaggctact tcttcatcca aatggacaag ttcacttcca caaactggac
    31381 aatgtgtagg caattggtat tcttcgctgt ctttaggtcg tttatctaac acgacttgcg
    31441 aaacttctgg gatgatgtct cccgctttat aaatcagaac tgtatctttc aagcggatat
    31501 ccttcaactt aatataatca ccgttatgca ggctggcacg gcttactgtc gttcctgcta
    31561 ctcggactgg tgtcatgata gctgttggcg ttactacccc tgttcgaccg actgtccatt
    31621 cgatgttttc gattagcgtt tcaacttctt ctggcggaaa cttgtaagct gctgcccatc
    31681 tcggtgcttt gatagtaaaa ccaagttgat cttgtagcga gaattcattc actttgatga
    31741 cgattccatc gatttcatag ggcaaatcca cacgtttgtc atgatattct tcaatgtatg
    31801 accacacttc atcaatcgaa tgacatagac gtttttcccg attcgtgtgg aatccaattt
    31861 tttctagctc ttctagcgca tcatactggg tttttgcttg cataggaccg aaatcagcta
    31921 ctgtgtataa aaaagtgtcc agatttcttt tcgctgtgat tttagaatct aactgacgca
    31981 aagaaccagc tgcggcgttc cgaggattcg caaagatatc ttttccctct gcttctctgt
    32041 cttggttcaa ttggacaaat gaccgttttg gcatgaaaca ttcgcctctt acttcgatgt
    32101 tcattggttc ttttaatttg attgggaccg accggacagt ttttaggttt tcagtgatgt
    32161 tttctcctac agttccatcc ccgcgagtcg cacctctcac gaaatttcca tcttcataac
    32221 gcaaagaaac ggaaagtcca tctattttta gttcacagca atagtcaact acacgtccca
    32281 ctgctttttg tacacgttga tcaaaagcta tcagctcttc tttgctgaaa acgtcgttca
    32341 aactgtaaag cggaatatca tgagtgactt tttcaaaacc ttctaatact tttccgccta
    32401 ctcgttgagt gggagaatca gacgtgatca aatcaggata ttgttcctcg attgctacta
    32461 attctgcgta ttctttatca taaacatagt cttccactgt tggtttatct tctacgtagt
    32521 attcgcgaga ccattggttc agtcttgtac gaagttcttc tgctcgttta gcagcttcgt
    32581 caatcgtcat ttcatgttcc atcatttacc ctccactact aagctttttc aattggcgca
    32641 aaggcagcca aaagacgttt tactccttga cttgggaaag ccacatctag ttctagatcc
    32701 ttcgacgtcc cgcttactcg gacgactgtt cctagacccc attttttgtg tttgacttta
    32761 tctccaggtt tccagctgtt attttcccct ccagtagcac ttttagaggg aacaaccgct
    32821 gtctctggct gtttatagct atatgctgtt tttttagcga atacaggcgt ttttttaggc
    32881 gtaggacgca tgccttcgat ttccagtaac tcctgatcga tttcttctac aaaacgagaa
    32941 ggtcggttat attgcgtccg tccatataat gttctggaga aagcatttgt taaatacaac
    33001 gcttcttctg ctcgcgtgat ccccacatat gcgagacggc gttcttcctc cagttcgctt
    33061 tcttccatca atgctcgaga taaaggaaaa accccctctt ctagaccaat caggaataca
    33121 actggaaatt ctaatccttt ggctgcatgc aaagtcatca atgtcacttg ggaagcatct
    33181 tcttctaaat tgtcaatgtc ggaaacaagt gccagatcat ttaagaagac cgttagtttt
    33241 tcttctggtg catcagcgtc ttcttcattt tgctgttcga attgtttgtc gaattcttgt
    33301 gtgaccgtta aaaattcctc caagttttcg atgcgtgctt gtgcttctaa tgtattttgg
    33361 atttttaagt cttctagata tccgctacga tccaaaacct ctttcgtcaa ttctgtcact
    33421 gtcaagtatg ggatcatctg agtgacttct tggatcatct ctccaaatgc acctaattgc
    33481 tgtcctgctt ttccaccgat atttgccaga tccacatttt gcgctgcttc aagcagtggc
    33541 cattcatgaa gagaagcaaa actgcgtagt ttttcgatag atcctggtcc gatgcctcgt
    33601 ttgggcgaat taacgatacg ctcaaaactg attgaatctt gaggatttac cagcacattc
    33661 aaatacgcta aaatatcttt gatttcttta cgatcgtaga acttgtgccc tccaaccatt
    33721 ttataaggaa tatttgcttt caacagagtt tcttccatta cacgagattg tgcgttcgtc
    33781 cggtacaaga tggcaaagtc gccgtaattc cgatgattgc ttcgaatctc ttcttgcatc
    33841 cggtctacga taaaacgggt ttcgtctcgt tcattatctg cacggtagta agtgatcttg
    33901 tttccttctt tgttttctgt ccacaagttt tttggttttc gattgctatt gttttcaatg
    33961 acttggtttg ctgcgctaag gatgtttttc gtggagcgat agttttgttc tagcaaaatt
    34021 actgcagcat ctggataatc tttttcaaaa tccaagatgt tctgcatatc tgcaccgcgc
    34081 cagccgtaaa tactttgatc tgcatctccc acgacgcaca ggttcctaaa tctacctgcc
    34141 aataaattga ctagcgtata ctgtgcgtga tttgtatctt ggtactcatc tacatgaata
    34201 taatggaatt tgttttgata atacgtgagt gaatcaggat gttcttcaaa taatcgaatc
    34261 gtattcatga tcaggtcgtc aaagtccata cattgattat attgaagctc tttttggtaa
    34321 gcagcataac attttgccgc aatctcttcg taataactgc cttgcatttt tgcaaaatcc
    34381 tgaggggtct gcaggctgtt ttttgcttga gagattgttc ctaatatact tcgaggatca
    34441 tattttttcg gatcaatgtt cagttctttt agtatccgtt tcatcaaggt cagctgttca
    34501 gaagaatcga tgattgtaaa gttccggtta tacccgataa aatcaacatc tcttcttaaa
    34561 atacgcacac acatcgagtg aaaagtcgat acccagacat cttcgcctcc agatgcgaga
    34621 atcgcattga cacgttcttt catttctttt gcagccttat tggtaaaagt aatcgctagg
    34681 atgttccaag gattgacttc tttttcctca atcaaatagg caatgcggtg tgtcagcact
    34741 ctcgtctttc cacttcctgc acctgccatt agcagtaatg gtccgtcagt gtgaagaaca
    34801 gcttctttct gacgggggtt catcccgttt aataattcag ctttggatga cattaacaac
    34861 atcctttctt ttatcaatct tgttaattat agcattttct tggctttcat taaactagct
    34921 agttcaaaat catttgtttc tttttatgga tttttccttg tcaattcgtt gatttcgcgc
    34981 taaattaaaa gaaagcgagg cgtttgaatg gaaaaaaaag gaaaaatcaa gaaattagat
    35041 aagactcaga tatattttat tctaaaagga atatttgttg gactgctgac aggaatcgtc
    35101 gttagcctgt ttcgattatc tatcgaaaag ctaagcgatt tagttcgaag tatctatgaa
    35161 atgagtcggg aacagccgat ttacttaatt ggcctagcta tttgctgcat ccttgcagca
    35221 tttttcgtgg gttatctggt caaaaatgaa ccggatatca agggaagcgg gattccacaa
    35281 gtagagggac agcttcgcgg ggaattatca atgaactggt tctctgtttt atggaaaaag
    35341 ttcattggcg gtgtactttc agttggtgcg ggcctttttc taggtagaga aggaccttct
    35401 atacagcttg gcgcatccat tggacaagga gctggacaat tgtttcggag tccatcttca
    35461 gaagaaaaga ttttaatttc tagcggtgca agtagcggac ttgcagcagc attcaatgct
    35521 cctatcgcag gattactctt tgttttagaa gaaatccatc actccttttc tccacttgtt
    35581 tggctgacat catttgcttc agcaatcact gctaacttcg tctctcttta ctttttcggc
    35641 ttgagacctg ttttatatct aggtgacctt ccttctttgc cgttgaaata ttatggttcc
    35701 ttagtgatct taggagtact tctaggcatc ttaggtttta tttatcagaa tgtcttgctg
    35761 gctttgccaa aattttacaa ccgattgcct ttaccagctt attttcacgg gttcgttcct
    35821 ttcttgctga ttttgccaat tggttattta tggcctagta ctctaggcgg aggcaatcaa
    35881 atcgttttag cttttggaca tgcttccttg ccaatcatta tgattatcgg tttgtttgtt
    35941 cttcgattcg ttttttccat gatttcttac ggtgggggtc ttccaggggg gattttcctt
    36001 ccgatattga cattgggggc tttaatcggt agcttttatg gaaacattat ggttgatttc
    36061 gggatggatc caatctacat caaggatttt gtcgttattg ccatggctgg ttatttcaca
    36121 gcgattggaa aagcaccgct gacagcaatt attttagtga cagaaatggt tggctctctt
    36181 aatcatctga tgcctttagg attggctgct cttgttgctt atatcgtcaa tgaccttctc
    36241 ggcggtaatc caatttacga atcattattg gaacgtctac ttggaaatac tcagaccgcc
    36301 tcactaaaag gtgcaaggac aacttttgat tttccagtaa cggcagagag ttctttagac
    36361 ggattaatgg tacgagactt caattggcct aaaaatatgc tgctaatctc tatacgcaga
    36421 ggaaatcagg aaatcttgac tcacggtgat acgatcatga atgtaggaga tattttggtt
    36481 atcttgactg atgaagcaaa cttgccaaga atcaagcagg aaatcgaggc taaatcttct
    36541 atcacaaatt tgaagcaatc attttaacga acatggaaaa actattttac aacaactatt
    36601 catctacact acttgattct atatgattct ataaaaaaag aagaggctgg gaaaacccag
    36661 cctcttcttt tttatttcta tgcttctgct actgcaggag cttttctcaa taaaccataa
    36721 atcacaccag atacgactgc tccgatagca ataaacacca aatacatgac cgggtgactc
    36781 agtaagaata caacgaaaat cccgccgtga ggagccagta atttgattcc gaaagctccg
    36841 actaatccgc cagttaaagc agaaccaata ataaaacttg gaatggcacg aatcgggtca
    36901 gctgctgcaa atggaatcga tccttccgtg acaaacgata gtcccatcac gatgttcgtc
    36961 aaaccagcat cttgatctgt tttgctgaat ttattcttaa acaaacgtgt agcaacgaaa
    37021 attgccaatg gaggtaccat tcctccagcc ataacagaag ccatcacgac acttccgcca
    37081 gttgcaacag tcgtagctaa agttgctgta ccaaacacat aagcggcttt gttgattgga
    37141 ccgcctaaat ctgccgccat cattccagct aataatgcac caagtaaagc agcattcgaa
    37201 ccactcatac ttgtcaagaa accgttcaat gcatcattga ttgctttcat agggacattg
    37261 accagcaaca tcaagaaacc agtaatcagt aagccaaaca ctggataaaa gaggatcgtt
    37321 ttaattccat ccaatgattt tggtaagttc ttgaataatt tacgtaaaaa tacgatgaca
    37381 taaccagcta agaatccacc aatcagtgca cctaagaatc ctgcaccgcc tgtattagct
    37441 aatgcaccag cagcaaatcc aacgatcaaa ccagggcggt caccgatact tgaagcaata
    37501 aatcctgcta ataccggcag catgaaacca aatgcagctt gtccgatttg gttgaaccag
    37561 ctagcagctt gattgtaatt ccctagattt gataattgat catgtggcac gccaataaat
    37621 tggtcgatca tgaaagaaag cgcaatagcg attcctccac caataacgaa aggtaacatg
    37681 tgtgatacgc cgttcatcaa atctttgtaa attctttgtc cgatagtacc atccgcattt
    37741 ccttcttctg aactgctttc ttttccatca ccatggaata ctggtgcagt accactaagg
    37801 gctagattga tcaactcttc tggtttacgg ataccatcac tgacaggacg attgatcagt
    37861 tcttttccgt caaagcgatt catctctact tttttgtctg ctgcaacgat tacaccttct
    37921 gcacgggcga tgtcttcagc agtcaatcgg tttttgattc cttctgaacc gttcgtttcg
    37981 actttgatct ccacacccat ttctttcgct tttttcttca aagcatcttc tgccatgtaa
    38041 gtgtgagcga tccctgttgg acaagctgta acggcaacaa cgaattttct ttctggatga
    38101 gcagaagctt ctgcagcttg tgtttcttgt tctgcttttt cttctgcttc tttttgctct
    38161 tcagctgttt ggaacaagtc ttggacttct tctggtgtat ttgcttcttt taattttcct
    38221 acgaaatctg catcaatcag caatcgagat agtgctgcta atgcttgcaa atgtgtgtcg
    38281 tttgcgcctt ctggagctgc gatcatgaaa aacagataag ttggctgtcc gtctaaggct
    38341 tcataatcta ctcctttttg gctttttgcg aataaaactg ttgcttcttt aactgcactg
    38401 tttttcgcgt gaggcatggc gattccatca ccaagacctg tagaagtttg tgcttcgcgg
    38461 gctagaattc cttctttata tgtttcgata tcggaaatcc ggccggcatc aaacattttt
    38521 tggaccattt catcgattgc gcctttttta tcagtcgctt gcaaatccat gatcatcgct
    38581 tctttgacca ttaaatcctt gatattcatg attatcctcc ttgaaactaa tcaatttttg
    38641 tgatttcaac ttctggcagc aactcatcaa tcaattcgcg agctgccaag tcatcagaaa
    38701 aagctgttgc gcttccgcaa gcaactcccc atttaaaggc ttcgattgga tctttcgtac
    38761 ggctgtaagc cccaataaag ccagcaatca ttgaatcccc tgcacctact gaatttttca
    38821 atgggcgaac taatacattc gttttataag ttccttgttc cgtgaagagc aaagcaccgt
    38881 ctccagccat tgagatcagc acattctgtg ccccttcagc tagtaatttt ttcccatacg
    38941 gaatgatttc ttctacagat tggaaggttg tgttgtaaag ctcagctaat tcgtgattgt
    39001 ttggtttgat caacaacggt ttcttaacaa gtgcattttt taggtcatca cctgttgtat
    39061 caatcacgaa atctgcacct ttttctcgaa tgatatcaat cagttcttga taaaatcctt
    39121 ttcgcaggct agctggcgcg cttcctgaca atacgacgat atctccttgt cctactgttc
    39181 ctaatgcttg cttcaactca tcgatttctt catctgaaat agatgggcct aagccattga
    39241 tctcagtttc agtgtctgat tttagtttga tattgattct tgtatcttct tttacggttg
    39301 tgaacaaaga ctggatttgt tctttttcaa gccacttcga aataaattcg ccagtgaacc
    39361 ctcctaaaaa ccctagtgct gtagattgag aatcgatccg tttcaaaata cgggaaacat
    39421 tgatcccttt tcctccaggt aacttgaagt cttccttcat tcggttcaaa tcgcctagtt
    39481 ttaacccatc tacgcgtacg atataatcaa ttgatggatt aagtgttact gtgtaaatca
    39541 ttgtattgcc tccttaattg ttgtcttttc acggaattca ttaacgaatt ctaatggaca
    39601 acgctcggtt atgatcgtgg ctgcttccaa aggtgcaaca gaggtgaagg acaactggtt
    39661 gaatttggta tgatcaatca atacaaatgt ctcttcggaa tttttcatgg ctaaacgttt
    39721 aacagctgcc tcttctggat ccggagtcgt gaatccttgt tcaagatggg caccgttcat
    39781 tcccataaat gctttattaa aatgaaaatt ttttagttgt tctatcgcat tagatcctaa
    39841 aacagcatta gttgccagct ttatcgttcc acctaaaata atggtagcaa gctccaaatc
    39901 aactaaattt gccgcatgtt gaacggaatt tgtcactact gtgatctgtt ttccttgcag
    39961 aaaaggaatc atttctaacg tagtagagcc agcgtctaaa taaatgacat cttcgtcatt
    40021 aatggtttca gctgccgatt tggcgatttg ctgtttttcg tgaacgtttt tgagtgattt
    40081 ttcactcata ttctgctcaa aattcaataa ttgctctttc ttagctccgc catgaactct
    40141 ttctagaaac ccactattct ccagctcttg taaatcacgt cttatcgttg attcagaagc
    40201 attcaaaagg tttacaagat cttgtgattt cacgattttc tgctgttcaa gcaagtctag
    40261 gattttttgt ctgcgttcct ctgtaagcat tttcacgatc acctcaatac aaataatagc
    40321 atattttttt tctactagca atataaatca gtcaaaaacg ttcataaaag ttataaatca
    40381 gtcaaaaaaa aaataaaaaa ccagtcagaa agactggttt tttatttttt tgtctatcat
    40441 caagccgttt tatcgttttt tattttcgct tcttgttttt ttcatataaa cagaagcagg
    40501 ttttctttcc ttatgaagaa gataataata aagtcccatc ccgccaaaca tgaccaaaaa
    40561 accgatgact gatcgaatag gaaaattagg aacaaaaaag agacagacgg ataataatga
    40621 tgccggaacc attattcgat aatagagttg tttatccatt ttcttcacct catatttttt
    40681 gtaaagtaat caattgttct aattctcggt aatctaaaaa ttgcacacgc agatgctgct
    40741 cacctttctt gacatcgaat tggatacttc gccgcttttt ctttattcgt ttgaaggtaa
    40801 catcagagag tctatgtttg atttccttta acggtaattc tgacagggat tctgaaggaa
    40861 catagattct taaggataaa agatactctt gatatttttc atctgttacc tctacttcta
    40921 gatattccct aatataataa caataagctt cgattccatt atccaaagca acagtcggat
    40981 cgataacttt atagcacatc atgcgtgatc gattctcgtc aacccaagga aaatacgcct
    41041 gagcatttag tgttccgcga acacgccttt ctttataatc tccttgttgg atatcataac
    41101 tttttgttac aaaaaatgaa gcattctttt taggaacagg ttgcatttgt gcattctgat
    41161 actggacaga ttggatcgta tggtcagtgt aaatgtattc aacgaatggc ggtttcaata
    41221 aaccgacacc attgtcccaa gcaagatgat caaacccaag ctggtcccta aaataggatt
    41281 gaaacatttg attgtttggc ttttgccagt taaaggggtc tcgataaagc tggatacata
    41341 tgacttcgtt ttctaattcc ttcacttttt ctacttgttg gatgtcgaga aaaatcggtt
    41401 tagggatgat ttgatgataa tagcgactat aatacatttc ccaacacgaa gtgaaacata
    41461 aaccttggta aaaaagatcg tatcctggaa attggttgca atcgactact acttccccgt
    41521 tttgttgttt cattttaggt aaatgttcga tttcatcctt tttctcaaac aatagccgtt
    41581 gagagatctg ttttgtattg tgatagataa actcgctata agctcgcata taggcgaaca
    41641 ccccatgagc aatcattttt ttctgaatga agtctcgaat caaaaattgc ttttctttga
    41701 aaacagagat agacaataca ttttttatca ataattgatt atcttccaag cgaaaactac
    41761 attcgttctc gtcatttcct acaactaacc aactttcgtc tcttaccgat gctagcatta
    41821 ttttttcttg aagctttcga agatcatacg gatccgcttg ttgtgtgaaa gagcggataa
    41881 atgttggctg gatcaacaga cgtgtcaaaa tagcccaatc gcttatttcc tgtttttttt
    41941 cttcttcatt taagtctgtg agctggatag tcatcaataa tttatcttcg ccaatcattt
    42001 tctcacctct ttcaaatctt tttataattt aattataacc aatgataaag aaaaactaaa
    42061 actttatgtc ttagaaacca atttggacga ttacatgata gactaagtaa aaagaaacaa
    42121 agaggtgttt acaatggggt tgaaatttga acgtacagat aatttagata aacttttcga
    42181 atcatttgct gtcgatccgg aaaaaacagt tgcaccaaaa gaagagatcg atcgatttct
    42241 aaaaccacag ccacaaaatg aaaagaaaaa agacaagaaa caaaagtaag ttaagctcaa
    42301 aaaaagactt accagccaaa cttttatgaa agagtttgac tggtaagtct tttttattct
    42361 ttttatgatt caattgcttg ttcgattgct gcccacgctt cttcttttcc ctgttttgta
    42421 acggaagaaa agagaataaa cgtgtcattg cgatcaaaat ccaacgcttt tttgatttcg
    42481 ctctcatgct tgttccattt accacgaggg atcttatctg ccttagtggc aacaacaatt
    42541 acagggatat cataatactt caaaaattga tacatctgga tatcttcttg agaaggctta
    42601 tgacgcaaat ctactaaaga aacgacagca cgtagctggt ctctagtcgt taaatatgtc
    42661 tcgatcatct ttccccattt tgctcgctca gttttggata cttttgcata cccatatccc
    42721 ggaacatcga caaaatgtaa tgcgttctcg atcaaataaa aattcaatgt ctgggtcttt
    42781 cctggcttac cggaagtacg ggctaaattc tttcgatcaa tcaatgtgtt gataaaagaa
    42841 gatttcccta catttgatcg tcctgccaga gctatttctg gcaattgtgt atctggatat
    42901 tgttttggtg ccactgcact tatgataatt tcagcttgat ggactttcat ggtctctctc
    42961 cttaacaagg tgatgaataa agcaagcggc tgtcgcaaaa gccaaaatga cttttacggc
    43021 agcctctttt catcaacccg cttttttctc tgaatcttta tagattactg ttggctcacc
    43081 agacaattca gctgcttctt ttgtgataat cactttttcg atgttttcat ttgaagggat
    43141 atcaaacatc acatccatca tgatttcttc aatgatggaa cgaagtcctc gagcaccggt
    43201 attgcgttcg attgcttttt tcgcaatggc tctcaacgct tcaggttcga attcaagttc
    43261 ggtattatct agagaaagaa gtttttgata ttgtttgact agcgcatttt tcggctcagt
    43321 caagatccgt accagatcat ctgttgtcaa tttctctaaa gctgccataa caggtaatcg
    43381 tccgataaac tcagggatca atccgaattt tagtaaatct tcaggaatga tatgctgcat
    43441 gacactttcg tcttcagaaa gtttttggtt ttgtgtacca aatccaatcg tcttttcgcc
    43501 catacgattc ttcacaatcg tttcgatgcc atcaaatgca ccacctacga tgaacaatat
    43561 gttcgtcgta tcaatctgaa taaattcttg atgtggatgt ttacgtccgc cctgaggtgg
    43621 cacacttgca acagttcctt ctagaatttt cagcaaggct tgttggacac cttcgccgga
    43681 aacgtcacga gtaatagata cattttcgct tttacgcgca attttatcga tctcatcaat
    43741 atagatgatc cctttttctg caagttccac attgtaatca gcagattgaa gcaatttaag
    43801 caaaatgttt tctacatctt cccccacata accagcttct gtcaaacttg tcgcatctgc
    43861 gattgcaaaa ggtacattca atgtttttgc taatgtttgt gctaaaaatg ttttaccaga
    43921 ccctgtaggt ccgatcaagc agatattgct tttttgcagt tcaacatcat ctgtgttttc
    43981 ttgtgcttgc tgattgacac gtttatagtg attgtatacg gcaacagcta acgagcgttt
    44041 tgcgcgatct tgtccaatca cgtagttatt caatacttca agaatttcta gtggtttagg
    44101 gacttcagtg aattcgcgta cagcttcttc ataaaattct tcatcaatga tttctttaca
    44161 taggtcgata cattcattac agatgtagac ccctggacca gctacgatct ttttcacttc
    44221 ttcttgggtt ttcccgcaaa aagaacagcg tacggtctca ttgctacttg gattgtcata
    44281 catggtcttc accccttaac ttgcaaaaag tatgcaagaa actatcaaag actttacagt
    44341 cttttactat cataacatag tttagtaaaa agaaaaagtg tttaacaaag gatcaactga
    44401 cctatacctt tgcatttttt actcttaaca aaaaataagg aactgtgaca aaatcgtgtc
    44461 acagtccctt atttcgaata aacaattttc tagaagtagc ttcttcagaa atgatttatt
    44521 acttgatttc tattctttcg cttctgtcgc tgtacctgtg atcaattcga ttgctttttt
    44581 cattgtcaca tcatgttcca gcatatcttc tgtcaacacg cgtttgattt gttcgattgg
    44641 catgttgtat gtttctgata attcttggat ttctgcattg atttcttctt ctgttgcttg
    44701 aagattttca gcagctgcaa ttgcttcgat cacaagattt gttcttgtgc gcatttctgc
    44761 ttcaccttcg aattgtttat gcaagtcttc ttctgtagaa ccagttaatt gatagtacat
    44821 ttcaggagag ataccttgac gttgcatgtt gttcaagaat tcgtccattg aacgatgtac
    44881 ttcatcatga accatcacgt gtggcaattc aacgatttct gcgttttcaa cagccatacg
    44941 gatcgctgct tcatcttttg catcgtccgc tgctttttct tttgtttcta ctaattcttt
    45001 gcgatatttt tctttcaatt cgtctaatgt tgatacttcg tcatcaacat cttttgcgaa
    45061 ttcgtcatct aattcaggca cttcttttgc ttttacttca tggattgtca ctttgaagac
    45121 tgcttctttt ccagcaagat cttctgcttg ataatcttct gggaaagtta catttacatc
    45181 tagactttca cctgatttat gaccaactaa ttgatcttca aaacctggaa tgaatgagcc
    45241 tgaacctaat tcaagtgagt aattttcgcc ttttccgcca tcaaacgctt cgccatctac
    45301 aaagccttcg aagtcgatta ctactgtatc gccattttca gctgcagcat cttctttgat
    45361 aactaattca gcttgtgctt cttgttcacg tttgatacgt gcatccacgt cagcatctgt
    45421 tacttcacgg tcttgttttt caacaactag atctttatat tgtcctaatt ttacttctgg
    45481 tttcactgtt acttcagcag tgattaccca gtcttgacct ttttccatgc tttcaacatc
    45541 gatttttggt tgagaaacag gatcgatgcc agcttctttg acagcagctt cataagcttc
    45601 tggtaataca gcattcaatg catcttcata taaagcttct tcaccgtaca tacggttgaa
    45661 tacttgacga gaaactttcc ctttacggaa tccaggtacg ttcaagcttt ttttcacttt
    45721 attaaacgca gttgttaatc ctttttggat ttcgtcttgc gcaatcgtaa attttaaaac
    45781 accatcattc gtgccttttt tttcaaatgt tgcagtcatt taattccctc cgagtttaga
    45841 aattcatttt atacatcaaa aacgtttcat gcataccttt aaatagtaca ctaacccttt
    45901 caaattgtaa acatattgaa tggatagaat ccttgttttt cataacattt ttatcttttt
    45961 cactgataaa atctaatgga agaagatcat ttgctgcaaa attttttctc ttttttttaa
    46021 aaaatcttgt ttttcatctt ctgtaccttc atacatcgtt tttcctgtac acgcctctac
    46081 agtcagttga aaccagcgct tcgggtcttc gatgtatgta tcatagacag gataaacaat
    46141 tgcagattgc aacgtgaatt cttcttttaa cacggaacta agcagcgcat cttcattccc
    46201 gtaacgatct gaaaatacac ataattgctg gtaacttgcc tgctgctgcg gctttggcag
    46261 atcttttggt atgactttga ctaacttttc ttcaatcgtc aaatagaaaa caggatggca
    46321 ttcgttcaat tgcctaagtg tctccagtaa ttttgccctt gctaaaatat ggacctctgg
    46381 cgatacaata agtttactcg ctgtttggat aaactcatga taaggaagct gttcgatctc
    46441 atcaatagac gcaagctgac gtgcaggttc caacgaagga agttcctccg atttattgtg
    46501 gagtgccttg atcttctgcc tctccatttg tccggataat tcttctgcaa attggatttt
    46561 ttcaatgacc cgctgctcga aagcttcata aaaatctgta cttgctatca attttctagc
    46621 atataaaaaa tcttgtgtac tgattaacaa gtcaaaataa aattcagcaa actcctcatt
    46681 ttgaagatac tgtttttcat gcaagagtgc ttgcttcaat gcttcttttt tctcgtccaa
    46741 ctcgtaaaga caaaaaacaa gcaggctatt agcctcaaag ctttctttca actcgtaagc
    46801 tcgttgaaat aattcttttg cctgctgata ttgctggttt gctagtgctt gttgtgccac
    46861 tcgcattaaa ttctcatatt tttctggaaa atcaatcggc ttcacgcagt gtcctcctct
    46921 tgctcatatt cagctcatgt tcaatagtag caaaacaaaa aaagcatgac aattaaaaat
    46981 aactgaagca ccctctaaaa gctagatttt agatctgact tttagaaggt gctttcaact
    47041 gttactgctt tttattgctc atcagctgtt gacttcctgg ttgaacgctt tgatcagatt
    47101 gatcgtaaca acacttgtat tagtgaaaaa atcgcccaga tgttgctttt tctgattaaa
    47161 gactgctgga agatacccta acatcagcaa aggaaatttt agaatgaacc ggcaagcacc
    47221 ttctctaact aaaacggttg accagctaag ttcttcttca tcaaagctga tgactcgaat
    47281 accaaagatc attttcccaa tcgtttggcc atgattgaat ttcgtcaata aaataaaata
    47341 cgctagataa ataagtaagg ctgtgaatcc gtagagactc agataagaat ctgaaaaatt
    47401 aagccaacct agatttttgg caataccaag tgttaaacgc gtaatagctc cgatacacaa
    47461 aagatcgacc aagaaggcaa acattcggat aaaaaaacct gcatagaaat acttaggaaa
    47521 atcatttgct tttggcggtt catttcttgt gtccgtatac tttttccatt tacgttgttt
    47581 ctttttgatt tcttcgggcg tcaaaggctc tctttcaaaa gagctcagta ccttttggga
    47641 aaagttggag tcaggtccta cagcaggctg ctgttgctta tctttttctt gttccttatt
    47701 ttcatttgaa agctctgaca tgcttactca cctccgtaat aatacattgc ttttggtgat
    47761 tccgctgtcc ctagattctc aagaacggat aagatctgac tagtctcaga aggcttcaat
    47821 ccctggaatt ctgctagttt acttcctaac catgtactag caaacccaga tggcgtggaa
    47881 gaatattcta ctagttccgc atcttcaagc tgttgttcct ttcgtatagc ttttaaagca
    47941 tcttcaggaa atcccaattc atcgactaaa cctacttctt ttgcttggac accatcataa
    48001 atccttccat cagcaatttt tttgacttct tcttcagatt tattccgtcc ctcgctgacg
    48061 attgctacaa aacgactata tgcgctgtcg atatatgctt gaagcaccgc ttcttcttct
    48121 tttgtctctg gtcgcgttcc tgaacccata tctttcaacg ctccgctttt aactgttgta
    48181 tcttccacac ccagtttttc tagaagtcct gaataattca atcctgacat gatcacacca
    48241 attgagccgg tcactgtttc ttctgttgca aagattttat ctgcttgagc agaaatatag
    48301 tagccaccgc tagctgccat gtttttcatg ctgacataca ttgggatatc atgttcttta
    48361 cgaatcgtat ccaatttctt agcgatttcc gcactttcgt agacaccgcc accaggagaa
    48421 tttacttcta aaaagatacc tttgactgtt ggatcttctt caatcgcctt cagttgttcc
    48481 ataaaatttt tatgattgta accttcagaa gcaaataaac ctgaagaccc tcccgcagca
    48541 atcgttccat ctactgataa ttttacgatt ttttgcgtac tgtctccctt ttccaacaca
    48601 tttggagcta gttcttcatc cccatataac caactgttca atccctcaat ttgatcgttt
    48661 tcctgaggct tagtcaaact agctgaaact aacgaaacca caaataatcc tgcagcaatc
    48721 agaactgctg cccaacgtct tttattcatt ctttctcctt tctaatacaa gttttttatg
    48781 acgatcacag tttctgactg ctcagaagtg tcgaaccgct ctgctttttc ttcccgcgca
    48841 tacccggaaa acgactcttt tgttaattca tcttctaccg taaactcacg agcttgagca
    48901 acttccaagg catcaggtgc gatttcttgg atgctatccc agccagtatc taaaaatatt
    48961 ttcgtatcat ctgatacacc agctgatgct tcgaatttgg acaattgttt ttttaacatt
    49021 cccagtgtca tgatctcaat ttttgaatcc atttttactc ctcctctatc cgattacttt
    49081 ctattgtacc gaactcctga aaaagatgat agataaaaac ccattatttt ttgacataaa
    49141 aaggacattt gacaaagaat ttgatatata ccaatttatt ttttattctt tttttgttga
    49201 caagaacatt cgcaaaaggt tatgatttta aatgtttcca gataaaaaac aaaaaggagg
    49261 atagttatac cttttaggat agcgccaggt ctgtgtaaac agatgacgag gagagggttt
    49321 atcgaaagat tcggcggatg gccctaggga ctgcactcta cagaaaatcc acaaaaaatg
    49381 tctgcaaaga taaaacaaaa ggattttcct gcagctggaa gcattcatac gaattcatta
    49441 tagaaagtag gatgtttttt atgtgcggaa ttgttggaat gattggatta aaaaatgtaa
    49501 caccaggatt gattgacggt ctagaaaaat tagaataccg tggttatgat tcagctggta
    49561 tctttgtctc agatggcaca actgattatc tggtcaaagc acaaggcaga attcaaaatt
    49621 tgaaaaacaa aataaatatt gatactacag gaaatatagg tattggtcat acacgatggg
    49681 caactcacgg gcaaccttct gaagaaaacg cccatccaca tacttcccaa agtggacgct
    49741 tcgtgctcgt tcacaacggc gtaatcgaaa actttgaaga acttaaaatt gcttatttag
    49801 caaatgacca ctttattggt gagaccgata ctgagattat cgctcatcta attgaaactt
    49861 tcgcgaagga tactacaacg caagaggcgt ttttaaaagc tttgcgggtc atcaaaggtt
    49921 cttacgcttt cgctttgatt gatcggacag cacctgatgt tatttacgtc gctaaaaata
    49981 aaagtccact attaatcgga ctcggcgatg gattcaatgt gattgccagc gatgcaatgg
    50041 ctatgcttgc tcatacgaag gaattcgttg agattgaaga tgaagagatg gttaccgtca
    50101 catcagaaaa agttattatt caaaattttg caggtgacat cgtagaacgt tcttcattcg
    50161 aagcacaagt agatgcttca gatatcgaga aaggtaccta tcctttttat atgctgaaag
    50221 aaatcgacga acagcctatt atcatgcgtc gtatcgctca aaaatacgta acagaagaca
    50281 atcgtgtctc tcttgatcaa aagctggtcg atacattgtc tgatagcgat cgaatctata
    50341 tcgttgcttg cggaactagt taccatgcgg ggttagcagg taaacagact ttggaaaaat
    50401 tgacacagat tcctgttgag gttcatttag ccagtgaatt tggctataac acacctcttc
    50461 tttcaaaaaa accattcttt attttcttga gtcaaagtgg cgaaacagca gacagccgcc
    50521 aagtgctggt aaaaatcaac tgtctcggct acccttcact tacgattaca aatgttgctg
    50581 gttctactct ttcgcgggaa gcatccttta cactgctatt gcatgctgga cccgaaatcg
    50641 cagtagcatc aacgaaagct tatactgcac aaatagctgt actaacttta ttagccaaag
    50701 ctatcggtga taaaaaagaa tttgaaactt ctcttgtatt cgatatcact catgaattga
    50761 gtttagttgc taatgcgatg gaatcggtca tcgcccaaaa agattattta gaagagttgg
    50821 cagaagtata tctcagcgat acaagaaatg ccttttacat tggacgtggt gctgactaca
    50881 acgtttctct tgaagctgct ttgaaattga aagaaatcag ttatatccag gcagaaggtt
    50941 ttgccgctgg cgaattgaaa catggaacga ttgctttgat cgaagaagga acaccagtga
    51001 tcggaatcat cagtgaagaa gtgactggtg cgcatactcg aggaaacctg aaagaagtcg
    51061 aaagccgtgg cgctaaaaca ctagttattg tctcagaggg attagaaaag gaaagtgacc
    51121 agctggtgct accaactgtc cacccttatc taactactct aaccacagtc gtaccgactc
    51181 aattacttgc atattacgca acgctattac ggggattcga cgttgacaaa ccacgtaatt
    51241 tagcgaaatc agtgacagta gaataataaa agaacaagga ccagtgtcag acatctgaca
    51301 ctggtccttg ttcttttatt ttttatgaaa atatctctta atccagtccg atttcttctt
    51361 tgactactgc cgcgatttta tcgacatagt aattaacttt ctcatcagta ggcgcttctg
    51421 ccatcactcg aagtaatggt tctgtaccgg aaggacgaac taggattctt ccttctgatc
    51481 ccatttcagc ttctgcctct tcaatcactt ttttgattgc cggaacatcc atcgcaccgt
    51541 ttttatcact tacgcggata ttcactaatt tttgcggata gattgttacc tctgctgcaa
    51601 gctctgataa tttcttacct gtctgtttca tgatattcag taactgaatt cctgaaagca
    51661 tcccatctcc agttgtgtta aaatctaaga aaatcatgtg cccagactgc tcgccgccaa
    51721 agttataatc gtttttgcgc atttcttcta caacgtaacg atcaccaact tgtgtaacga
    51781 catctttcaa accgattcct tccaccgctt tgtggaatcc taagttactc atgacagtcg
    51841 taacgatcgt atcttttttc aatcgatttt tttctgccaa gtatttagca cagataaaca
    51901 tgattttatc accgtcgaca atgtttccaa gttcatccac cgcaataata cgatcgccat
    51961 cgccatcgaa agctagtcca gcatctgctc ctttttcaac gaccatctca gctaaacgtt
    52021 ctggatgggt agagcctacg ccgtcattga tatttaaccc gtctggattt gtgcccattg
    52081 tataaaaatc tgtttcaaga tcggcaaaca aacgattaac acttgttgaa gttgctccgt
    52141 ttgctgcatc gacacaaatg gtcaaaccgg aaaggtcacc gttgatcgtt tgtacaagga
    52201 attgagaata tttcaataag ccttctggaa attcttctac agttcccaat ccttcagctg
    52261 atggacgagg caattcatcc acttcagcat ctaataatgc ttcaatttct agctcttggt
    52321 catctactag tttaaaacca tctgcaccga aaaatttgat tccattatct tgtgctggat
    52381 tatgagaagc agaaatcatg acccctgcgc ttgctttttg caaacgtgtc agataagcaa
    52441 cacctggtgt agagatcaca cctagctgga acacttcgat acccaccgat aaaagtcctg
    52501 aaatcagcgc ttcttctaac atttgacctg agattcttgt atcccgccct actaacacgc
    52561 gtgggcgttt tccttcttct tcatgctggc ttaggacata acctccgcac cgtcccagct
    52621 taaatgcaag ttctggcgta agttccttgt tggcttcacc gcgtacgccg tctgttccaa
    52681 aatatttacc catagttgta aaattactcc tttaacttaa ttttctgagg aatttgttct
    52741 gctcatttgt gttgattcgc ttgtttctga tgtttcttct gtacttgtgg tcgagctgct
    52801 tgtcccagat tccgaactgg aagaaatggt tgttgtcgat ggttccgttc ctgaatcagc
    52861 agatgaaata cttctactcg tacttgtatt ttcttgtgtc cgactgctcg tcgaagcaga
    52921 gctactgctt gacgtttgca acacgggtgt aatctccaca ctaactgatt cgggcttgat
    52981 acttaacccc tcttctactg gtatttcaat tttacgagtt gttcgatgat tgatacctga
    53041 gacattgatc ggtacagcaa tactgtcacc gatcgatgca agcaaatcgc tagagccgct
    53101 tacttctgct tccagttttg aaaaactgaa atcatagctt tctaccccgg cagctggtgt
    53161 tccttgctgt atcccataaa gtcgtaccga cttgcttggc ttgatcgaat cagctctcac
    53221 tgttacttgc actggatcag agacgatact taatacttcc cctgctgcat tcagcgcctg
    53281 tattgggacc tcactattaa tcccatcatc tgtgaccatc gaagcgtcca catcagctac
    53341 tactcgtttg atttctgcca atgttttgtc acctgtagtg atagagactt ttttaggact
    53401 aacggaagta tcatcaagtt catatccaga tggtgtgaac gttgaaggaa tcaacgtttc
    53461 cacatcgaaa tcttttatta cctttttctc aaccgttact gtaatagtcg atggttcgat
    53521 ctttgctgtg acagcactgc tcaaattttg aatttttagc ggaacttcat gtgttccttc
    53581 gcccagctta gtgatatctg ctgtgacgcg gaacatccgt gtatcttcgt ttgcctctgc
    53641 attcaactga actcggtttg cactggaaag tttgacagtc actgcatttt catatccatg
    53701 gatatagtag cgctttgaat cataagaaat cttgatcggc acccccgtaa ctgtttgatt
    53761 atacgcttca tttccagaaa gcgtatttgg aacggactgg ccatttgcat tgaagtacag
    53821 cgcaatactg aacagcaatg caataaaact gtaaagaatg cttgtccgtt tctcttttga
    53881 gatcatttgc gatcccctcc cttagtcata ccgtctagga aagattgaat cacgtttttc
    53941 ttgttttttg ttttctcttc agcaattagt tctctacgca agattgccaa atattcttgc
    54001 tgggataagc cagccatcag ttcattatct aacgtgatgc tgacgtcccc ggtttcttca
    54061 gagacaacga tggtaatcgc gtcactgact tcgcttatac cgacagctgc ccggtgtcga
    54121 gtcccgaatt ctttagggat caacatactt tctgatagag gaagataggc gcttgctact
    54181 gcgatctttc cttcttttac aataactgca ccgtcatgca gcggtgtatt aggaataaag
    54241 atattgatca gcagctcccc agtgatatct gcatctaaag caatccctgt ctcaatatac
    54301 tcatctaatc cagtatgacg ttcgatagtg atcaacgcac cgatttttcg cttggacata
    54361 tattggatgg ctttgtcaaa agacaagatc atcttctcat cttcctgctg ttcgcttttt
    54421 gattgtttga aaagcgaact gcgtccaaga tgttccagtc ctctccggat ttccggctga
    54481 aaaatcacga tagcagctat caccccgtac gtaatgactt ggttcatcag ccaagacaag
    54541 gtgtgcagac caatgatttc cgctacgatt cggataacaa taaaaatagc tacacctttc
    54601 agaagctgaa tcgcttttgt gcctcgcagc agttggatca gtttgtatac aagataccag
    54661 acaaccagaa tatcaagtat gttcaccaaa aaattcagag agaacaagtc accggaaaac
    54721 atttgctgcc aatagtccaa attaaaaagt tccccgattt gaaatgacat aaaaagcctc
    54781 tcttctcttt tgagatttcc tctctagtat atcatatgtt ttaattttag aggctgatat
    54841 gctcgtattt ttcttgagaa aaacgcataa ttttcaagaa aattgcaagt atgcgtttta
    54901 tttttctctg caataaatat ttttaaactt cagagaatta ttcattatat tttttctgtt
    54961 atttttcctt tttttctttt gtagcttgtt ccattttttt acgtcgttct gctctggcag
    55021 ctcttctagc agctcttctt tcttctgctt caaggtccgt cgttttttct tttctagtct
    55081 taacgggtac atcgatagat tcctctggtt caagtcgttt cttgattttt tctaattctc
    55141 ccgtcagtgc agcatagttg taaaaacgtg ttttagcgtc gtggacagtc ttttcaaata
    55201 aagcttttgc aagatttgga tttgcgttat ctagcgagga aaagcgaact tgtttcctca
    55261 tgaaatcagg catagcagag aaatcaggtt ttttgtagtc caaagtcatt gggttcttgt
    55321 ttttttcgac cattgtaggg ttatatcgat ataatgacca ataaccagaa gaaacagctt
    55381 cttttgcttc tttaagcgat tctttcattc cgccaagcaa gccatgtgtg atacaaggcg
    55441 tataggcaat aatcagagaa ggaccaggat acttttctgc ttcttcaaat gccttgatcg
    55501 tttgcatttg attggcacct gaagcaattt gcgccacata aacatttcca tatgtcatcg
    55561 ccatcattcc tagatctttc tttgaagcat actttccact agccgaaaat ttagcgattg
    55621 ccgaagctgg tgttgctttt gaggtttgac cgccagtatt ggaatagact tcgttatcca
    55681 aaacaaggat attcacgtct gctccgctgg caagtacatg atcgatcccg ccaaaaccaa
    55741 tgtcgtaagc ccatccgtct ccaccaatca tccattggct gttttttacg aatagatcct
    55801 ttctcttgta tatatcctcc agttcaggga aaattgatcg ttcgctttcg atcgcagctt
    55861 gcagttttgc tgctctttgc tgcgttcctt cactctcaaa catgtgtact aaccagtctt
    55921 ccatcaattc tcgtagttct tctgatactt ttggcaatac ttctttgatt gaacttgcca
    55981 aagcctcgcg acgagtctgt gccgctagaa gcataccata accaaattca gcattatctt
    56041 ccaataaaga atttgaccat gcaggccctt gaccacattc attggtcgta taaggagaag
    56101 caggagaagc accgccccaa atagaagaac agcctgtcgc attcgcgatc atcattcgat
    56161 caccgaacat ttgtgtcaat aattttacat aaggtgtttc gccacagcct gagcaagcgc
    56221 ccgagaattc aagaagcggt tgattgaatt gtgtagacaa gacagtattc tttcctttga
    56281 ctggatttgc tttttgtctt aatgtcattg caaaagccca attcacagct tgttctttct
    56341 gttcttcata aggcttcatc actaaagctt tttcttttgc gggacaagcc tctacacaca
    56401 gaccacaacc tgtacagtct tccactgaaa cttggatacg gtattttacg ccgtctgcgc
    56461 ctcgcatttc tctcacgata aatccttctg gcgcttcttc catttcctct tcatctgcta
    56521 aaaatggacg gatggcagca tgaggacaaa caaaggcaca ttcattacac atcgtacagc
    56581 gatcactaat ccactcaggt acttctaaag cgacgccccg cttttccata gaagccgttc
    56641 ctaaaggcat ttcgccagtt gtcattccat ttgctacaag tgtaccaaca gagagttgat
    56701 ttccttcctg tgcattcact ggttcaagta tttcttgtat ataaccagtg ttccttttat
    56761 tgattttttc aggcatctcc aacgttctcc aatggtctgg gatcgcgact tgatgaagca
    56821 gttcggtcgt ccgatcgatt gcttgtatgt ttttttctac gatagccatt gatttatgtc
    56881 catagctttt cagggcttct tcttttagca gcggaagcac ctcatcaaaa ggaatgatgt
    56941 cagctaattt aaaaaaagcc gtttccattg ccgtattgat ccggcgtccc aaaccgactt
    57001 cttgggccaa tctcatggca ttgatcgtat agaatctaat gttattttca gccaagtaac
    57061 gttttaattt taagggcaga tgcgtttcta attgttcgtc gctccaaaga gtattcaata
    57121 aaaaaatgcc acctggcttc aatcctttga ccaagtcata gctatgcagg taagctggtg
    57181 tgtgacaggc aacaaggtcc gcatgctcga caagatacgc tgaacgtatc ggcgtatctc
    57241 caaaacgaag atgagagaca gtcagaccgc cagatttttt cgaatcataa taaaaatagc
    57301 cttgcgcata tttatcggtg tgatctccaa taatcttgat agctgattta tttgctccaa
    57361 ctgttccgtc agatccaaat ccccaaaact tggcctggaa tgtttgcggt tctgtcaaat
    57421 ccagactttc ctttggttcc aaagattgat aagtcacatc atccacgatc cctatggtaa
    57481 accgtttttt gcgtatgctt gggtcttttt tcaattcatc aaaaactgct gagatttggt
    57541 cgggagtcac atctttagac cccaatccgt agcgaccacc aataacagcc gggcgaagtt
    57601 cagaatcata taacgcactt tgaacgtcta ataagagagg ttctccacct gcccctggtt
    57661 ctttacttcg atcaagaaca gcaattgttt ttactgtatg aggcaacttt tgcacgaatg
    57721 tttccactgg aaaaggacga taaagatgga tattcaaaaa acctgttttc cgtccgtttg
    57781 cattcaagta atcaatcgtt tgttcaatcg tctgtgcaac tgatcccata gaaacaatga
    57841 cttcttccgc atcgtctgct ccgtaataag tcaccaagtc ataagaagtt cctcgtaatc
    57901 ggttgatctc tttcatatat ttttgaacga tttcaggtaa tttatcataa taggggttga
    57961 tcgtttcccg ttgttgaaaa tggatgtctg gattctggtt cgtaccacta acagtcggat
    58021 gattgggatt catccctcgt ttacgaaatg aagctaattt ctcctgattg atcagaggag
    58081 ctaattcttc atattccaaa acttcgattt tttgaatctc gtgactcgta cggaatccat
    58141 caaagaaatt caaaaaaggg acttctcctt caatagaagc aagatgggca acaggtgcta
    58201 aatccatcac ttcttgtaca ctgctttcag ctaacatagc aaatcctgtt tgtcttgcag
    58261 ccatcacgtc tccgtgatct ccgaaaatat tcaacgcatt tgtcgtcact gcccgactag
    58321 caacgtggaa aacacttggc agtagttccc cagcaatctt gtacatattc ggtatcatca
    58381 aaagcagccc ttgtgaagcg gtatatgtag ttgtcagtgc accagttttc aatgatccat
    58441 ggaccacacc agctgctcct gcttcggatt gcatttctac tacttttact ggttgaccga
    58501 atacgttttc ttttcctgct gctgaccatt gatctactaa ttcagccatg gtcgaactgg
    58561 gtgttattgg atatattgca gcaatctcgg taaatgcata agaaatatat gcggctgccg
    58621 tattgccatc cattgttttc atttttcgca tgattcatca tccttgttca tattctctct
    58681 tattatctgt tccattataa cgtaaaacat gccatttttt tcttttattt ataaaaatat
    58741 tttacatgta tctatttgaa ttggtcatct aatttttaga caaacagtct aaatcgttgc
    58801 ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca tggatatatc
    58861 agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt catcgaatgc
    58921 tcctaaaaaa atggtcgaat tcatcaactt agcttgtccg tattgccgac aatggtttga
    58981 agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc gagtgatcaa
    59041 attgttcgat aaagaaaaag aaagcttaca gcgagggaac gtgatgcacc ggtatctcac
    59101 aatcagcgat ggccaaaaag cgatcaaaga gatcaaacaa atattcgata ctcaagacga
    59161 gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac taaagctgac
    59221 agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc aagcacatat
    59281 tcgatttgtt ccaactgtca tcttgggtaa agaaatcttt gatgaatcta tttcaataga
    59341 ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtggga caaaagtaaa
    59401 gaacactttt gtctcacgct ctaaacacgt ataaacggcg gaagcagaag caactccttc
    59461 ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa atggtgtcca
    59521 aaagcttgca tctgccagat tatctcattt cttatgacaa gctaagcaaa ttatctccac
    59581 caaataattt attcatattt ttgacttgcg catactaact aattcttaaa ttttcataca
    59641 aaatttctca atttccctta acgagtaata tttatgtacg gtgattctca ctagtatccc
    59701 aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc ttttatgtat
    59761 gctgttagtt gattagatgg tcatttgttg agctaggtcg tttattttaa acaagttgtt
    59821 tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa atgcatacgc
    59881 atctgtattt gccactttga ttcgtataaa gctaacaact attaactcct ctcagctaat
    59941 agttgctctc ttttttattc agattcattt ttgctgatca cagcctagta tttcaatggt
    60001 tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa atggattagt
    60061 agatttcgat tattcaaagc gattttctat tggtggatcg tgttcccaac taataagacg
    60121 gattccaaac ctatcgtaca gatcttctaa accacttata aattttgcac ctatttcagg
    60181 tgttttattg cgtggatatt ctattgttac gccattaaat ggataccaat taggattagg
    60241 ctctcttttt ttctgtacat ctcccataga atagttagca ctttctggga cataatatat
    60301 tcttcgacca tcctctaatt catctaataa gatatttcgt gatcgtctat cacttgctaa
    60361 atgtagacgc cacgtgcgat accatgccat gctacctgca tctgcagaaa atccatcaaa
    60421 taatgcaaca attgtatctt ctatcacaat cctttcccca tctacttcat attctaatct
    60481 aaaatcaaac tcccctcggg taatttctgg tcttggtggc ttaggaccca atattattct
    60541 acttaaaacc gcattcgttc ccagatgaaa cacagctata acaacaataa tgattaatat
    60601 tttgtttcta tttgataaat ttctcattat tcgcacatca cctctacatt ctcacatatt
    60661 agttcgtaat actcctttaa tatcaaaata tctactggtc gtaataatat tcgctatgaa
    60721 ttcctactac tcgtataaga aaggccaaat catcagcttt tacttgctga tgatttggct
    60781 tgtttctatt tatcgtaatt gttttctaat caccaaaatt gttaacaatc ggttcagata
    60841 tttcccagtt gattaaggta attccgtatt gtgtcaaaac ttcttgcgct tctccgaaat
    60901 taagtacagt tcttatgtat ccactttctc ctaatataaa gtctacctct cttttaaaac
    60961 cttcctcgag atttctaagg gctatatgtg gttttaatga cattgattgt acattttccc
    61021 ccatataata ttgcgcactt cctcgactaa aatagattcc tagatcgtcc ccaaaaggta
    61081 gatcttctct accactagct aatctacttc tccatcttcg ttctcttttc atagaacctg
    61141 cgctgaactc acacccgtta aactcagcta tgacagtatc ttcaattatg ttaatctgtc
    61201 catctagttc gtattcaatc ctaaatggaa attctccata ggtgatttcc ggttcgggta
    61261 ttttaggtga gattaatgca aagaaaggaa atattaagct tggcaacatc aaaaaaactc
    61321 ctcctatgat cacaattccc gatgtaatcc aaaatataat ttgtacaatt ctcattgatc
    61381 cattgtattc cattttattc cccctattac tattcatatc cgcctatcta tatcgatctt
    61441 ccaatgcaga gataattgct tccatacctt gattttttac tgagttacct atgcgagata
    61501 tcattctcca ctaaggtgca tcatattgtc tatctaacat gattaattct ccaataggtg
    61561 tatactcctc caaaaacaac atttaatgca tctccctcga caacataagc taccatgttt
    61621 gctgtatatg tgtttgagtc taattcataa gcagataaat ttactgtcgc tggattaaat
    61681 ataatcgcat tcgtatttat agctactgaa tttgctgctt cagcaccacc ttttgaatgt
    61741 ccgatcattg tgatttcaat agtaggattt acgtggacag ccctcaccgt ttaccctgac
    61801 cattatagaa atcgcttact tttttgaact acgcaacaaa ggatacaatg ctcctaactt
    61861 cactgtctcc atttttgtcc actaaggaat ataaaaaata ggcattaatt catttaattc
    61921 ggtcacaaca cgttaccttt taaatcatta tactgtatct catacattat tatcaataaa
    61981 ctattataaa aatgcaaaaa atgctttatc aatctatttt gtaattggtc ataatatcat
    62041 tgaaatcata ccctgtatcg atttttccta tgaatctcgt ctatttgtga ttgacgaaaa
    62101 agaggcaaga cagacactgg aatggtaatt ttacccacta ttttgctcca actatttgta
    62161 atcgtaccca cttttgaaat accgagatga tcattttaat tgatatgctg attcccaagc
    62221 aaaaccccaa gaaattaaat gctctatcgc atctagcttc ttgggttttg cttatataaa
    62281 ttccaacatt taaatttttt atgctgttcg gtctcagaaa tgctgttttt gcttatatca
    62341 caatatcaag atgtcaaatt attcgtgttg ccgatgactt tgattaattt ttttcaaatt
    62401 gtttattaag actaatgctg tctttttgca gataccaatg ttcgaacttt ttaacattat
    62461 catatgatcc tgcaagtttt aacttcttac cattagatgt tatcaaagtt ataattaacc
    62521 ttgccttttt cccattagga tcttttattt tatgaatttt ctgcaggtaa tctctcctaa
    62581 tggcagctat ttttacctca tcagtgctga taaaccattg atcatccaca tacatactgc
    62641 ctgttatgtt gtgtttttcc atttcttccg agaacgaaaa gtttaaggct cgttcttact
    62701 tccaaagttg aatgagtcca tggattggac ttagtgtgag aattgagaac aacaataaga
    62761 atccatatcc tcccgcaaac atccctaagg ctatactgtc tctccatcca taagtaggat
    62821 tagaagagaa aagagtcacc gtttgtaata atatgaaaag gaataatcca gcacaaacac
    62881 caaagataac aactccaaac attgaatttt tatacaatga ccatttattt acaggctttt
    62941 ctttcatttt acttccccct actgttctgt tcacacggaa tgaattcaaa gttcataagc
    63001 cctcctcttt gaacatatga atacgacttg ctaactatac tttaaaaaag cttgttttaa
    63061 gcggttatag gcgagttgta atctctattc atctcattag caaataactt gccgaaaagt
    63121 ctactgaaat taaagcagat agtggaagaa ttatttagcc aggatagaca ctatttgtga
    63181 aacacatgtc tttacttttg aaattctatg atgaaaagcc ttggaataca gtagctctta
    63241 attggtaata ctttttccat tataaataac ctcttttc
//
LOCUS       DAPBCF010000009        62270 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.009, whole genome shotgun sequence.
ACCESSION   DAPBCF010000009 DAPBCF010000000
VERSION     DAPBCF010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 62270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.009"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(148..2301)
                     /locus_tag="RD508_000749"
     CDS             complement(148..2301)
                     /locus_tag="RD508_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HDT7735365.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2696..3544)
                     /locus_tag="RD508_000750"
     CDS             complement(2696..3544)
                     /locus_tag="RD508_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7735366.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3768..5708)
                     /gene="thrS"
                     /locus_tag="RD508_000751"
     CDS             complement(3768..5708)
                     /gene="thrS"
                     /locus_tag="RD508_000751"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDT7735367.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(6045..6224)
                     /locus_tag="RD508_000752"
     CDS             complement(6045..6224)
                     /locus_tag="RD508_000752"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HDT7735368.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6271..8094)
                     /gene="cadA"
                     /locus_tag="RD508_000753"
     CDS             complement(6271..8094)
                     /gene="cadA"
                     /locus_tag="RD508_000753"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDT7735369.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGVKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8372..10651
                     /locus_tag="RD508_000754"
     CDS             8372..10651
                     /locus_tag="RD508_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7735370.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETEIDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10744..11391)
                     /locus_tag="RD508_000755"
     CDS             complement(10744..11391)
                     /locus_tag="RD508_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735371.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNNVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11570..12289)
                     /locus_tag="RD508_000756"
     CDS             complement(11570..12289)
                     /locus_tag="RD508_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7735372.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12420..13571)
                     /locus_tag="RD508_000757"
     CDS             complement(12420..13571)
                     /locus_tag="RD508_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDT7735373.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKTTGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTYSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDVGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13788..14528)
                     /locus_tag="RD508_000758"
     CDS             complement(13788..14528)
                     /locus_tag="RD508_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7735374.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEIFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14532..14888)
                     /gene="rsfS"
                     /locus_tag="RD508_000759"
     CDS             complement(14532..14888)
                     /gene="rsfS"
                     /locus_tag="RD508_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDT7735375.1"
                     /translation="MIDSKEQLKIAVEAADSKRAEDIIALDIRNVSLLADYFMICSAN
                     SERQINAITEEIIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERSFYNLE
                     KLWSDAPLVDLSEWLD"
     gene            complement(14912..15505)
                     /gene="yqeK"
                     /locus_tag="RD508_000760"
     CDS             complement(14912..15505)
                     /gene="yqeK"
                     /locus_tag="RD508_000760"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HDT7735376.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15489..16139)
                     /locus_tag="RD508_000761"
     CDS             complement(15489..16139)
                     /locus_tag="RD508_000761"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDT7735377.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16149..16460)
                     /gene="yhbY"
                     /locus_tag="RD508_000762"
     CDS             complement(16149..16460)
                     /gene="yhbY"
                     /locus_tag="RD508_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HDT7735378.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16476..17585)
                     /gene="yqeH"
                     /locus_tag="RD508_000763"
     CDS             complement(16476..17585)
                     /gene="yqeH"
                     /locus_tag="RD508_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HDT7735379.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNEIQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17582..18109)
                     /locus_tag="RD508_000764"
     CDS             complement(17582..18109)
                     /locus_tag="RD508_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HDT7735380.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18336..19121)
                     /locus_tag="RD508_000765"
     CDS             complement(18336..19121)
                     /locus_tag="RD508_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HDT7735381.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRFDQHELLEKRYKRFRQY"
     gene            complement(19114..19983)
                     /locus_tag="RD508_000766"
     CDS             complement(19114..19983)
                     /locus_tag="RD508_000766"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HDT7735382.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHML
                     LELHTQKGWIDRG"
     gene            complement(19984..21363)
                     /locus_tag="RD508_000767"
     CDS             complement(19984..21363)
                     /locus_tag="RD508_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDT7735383.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPTRHIEVQILGDHF
                     GNVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21371..21790)
                     /gene="fabZ"
                     /locus_tag="RD508_000768"
     CDS             complement(21371..21790)
                     /gene="fabZ"
                     /locus_tag="RD508_000768"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDT7735384.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21815..22291)
                     /gene="accB"
                     /locus_tag="RD508_000769"
     CDS             complement(21815..22291)
                     /gene="accB"
                     /locus_tag="RD508_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDT7735385.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPETMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22294..23529)
                     /gene="fabF"
                     /locus_tag="RD508_000770"
     CDS             complement(22294..23529)
                     /gene="fabF"
                     /locus_tag="RD508_000770"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDT7735386.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIIGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23548..24285)
                     /gene="fabG"
                     /locus_tag="RD508_000771"
     CDS             complement(23548..24285)
                     /gene="fabG"
                     /locus_tag="RD508_000771"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HDT7735387.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24297..25214)
                     /gene="fabD"
                     /locus_tag="RD508_000772"
     CDS             complement(24297..25214)
                     /gene="fabD"
                     /locus_tag="RD508_000772"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDT7735388.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25321..25545)
                     /locus_tag="RD508_000773"
     CDS             complement(25321..25545)
                     /locus_tag="RD508_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDT7735389.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25598..26560)
                     /locus_tag="RD508_000774"
     CDS             complement(25598..26560)
                     /locus_tag="RD508_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDT7735390.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26570..27010)
                     /locus_tag="RD508_000775"
     CDS             complement(26570..27010)
                     /locus_tag="RD508_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7735391.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27316..28281
                     /locus_tag="RD508_000776"
     CDS             27316..28281
                     /locus_tag="RD508_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDT7735392.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRAQLPDLQ
                     EMTFEQKKKELQGLFQGQNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKHFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMIASADVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQSEIELLNKKEAEKQLN"
     gene            complement(28338..28568)
                     /locus_tag="RD508_000777"
     CDS             complement(28338..28568)
                     /locus_tag="RD508_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HDT7735393.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28654..29541)
                     /locus_tag="RD508_000778"
     CDS             complement(28654..29541)
                     /locus_tag="RD508_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDT7735394.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(29630..30853)
                     /locus_tag="RD508_000779"
     CDS             complement(29630..30853)
                     /locus_tag="RD508_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDT7735395.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30870..31916)
                     /locus_tag="RD508_000780"
     CDS             complement(30870..31916)
                     /locus_tag="RD508_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDT7735396.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYSIRVPIQAISNGIDLEKYRPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(32080..33807)
                     /gene="ptsP"
                     /locus_tag="RD508_000781"
     CDS             complement(32080..33807)
                     /gene="ptsP"
                     /locus_tag="RD508_000781"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDT7735397.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(33807..34073)
                     /locus_tag="RD508_000782"
     CDS             complement(33807..34073)
                     /locus_tag="RD508_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HDT7735398.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34552..36786
                     /locus_tag="RD508_000783"
     CDS             34552..36786
                     /locus_tag="RD508_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7735399.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36934..37254
                     /locus_tag="RD508_000784"
     CDS             36934..37254
                     /locus_tag="RD508_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HDT7735400.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37459..37683)
                     /locus_tag="RD508_000785"
     CDS             complement(37459..37683)
                     /locus_tag="RD508_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HDT7735401.1"
                     /translation="METEWQIRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37881..39461)
                     /locus_tag="RD508_000786"
     CDS             complement(37881..39461)
                     /locus_tag="RD508_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HDT7735402.1"
                     /translation="MNNPELKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(39862..41238)
                     /locus_tag="RD508_000787"
     CDS             complement(39862..41238)
                     /locus_tag="RD508_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDT7735403.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(41366..42484)
                     /locus_tag="RD508_000788"
     CDS             complement(41366..42484)
                     /locus_tag="RD508_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7735404.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            42626..42906
                     /locus_tag="RD508_000789"
                     /pseudo
     CDS             42626..42906
                     /locus_tag="RD508_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(42984..43517)
                     /locus_tag="RD508_000790"
     CDS             complement(42984..43517)
                     /locus_tag="RD508_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HDT7735405.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(43611..44789)
                     /gene="mutY"
                     /locus_tag="RD508_000791"
     CDS             complement(43611..44789)
                     /gene="mutY"
                     /locus_tag="RD508_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HDT7735406.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(44782..45579)
                     /gene="recX"
                     /locus_tag="RD508_000792"
     CDS             complement(44782..45579)
                     /gene="recX"
                     /locus_tag="RD508_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDT7735407.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNRGKSQKELLRKIQQTLMTKGFSQEVIQQAMADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            45686..47068
                     /gene="rlmD"
                     /locus_tag="RD508_000793"
     CDS             45686..47068
                     /gene="rlmD"
                     /locus_tag="RD508_000793"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDT7735408.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMICEINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(47242..47820)
                     /locus_tag="RD508_000794"
     CDS             complement(47242..47820)
                     /locus_tag="RD508_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HDT7735409.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            48142..48612
                     /locus_tag="RD508_000795"
     CDS             48142..48612
                     /locus_tag="RD508_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HDT7735410.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGEYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(48720..49946)
                     /locus_tag="RD508_000796"
     CDS             complement(48720..49946)
                     /locus_tag="RD508_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7735411.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(50700..50900)
                     /locus_tag="RD508_000797"
     CDS             complement(50700..50900)
                     /locus_tag="RD508_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7735412.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(51034..51642)
                     /locus_tag="RD508_000798"
     CDS             complement(51034..51642)
                     /locus_tag="RD508_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDT7735413.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNAAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(51727..52197)
                     /locus_tag="RD508_000799"
     CDS             complement(51727..52197)
                     /locus_tag="RD508_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HDT7735414.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(52245..53159)
                     /locus_tag="RD508_000800"
     CDS             complement(52245..53159)
                     /locus_tag="RD508_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDT7735415.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKNVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            53305..54108
                     /locus_tag="RD508_000801"
     CDS             53305..54108
                     /locus_tag="RD508_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HDT7735416.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            54286..55233
                     /locus_tag="RD508_000802"
     CDS             54286..55233
                     /locus_tag="RD508_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDT7735417.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(55301..55594)
                     /locus_tag="RD508_000803"
     CDS             complement(55301..55594)
                     /locus_tag="RD508_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HDT7735418.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(55622..56287)
                     /locus_tag="RD508_000804"
     CDS             complement(55622..56287)
                     /locus_tag="RD508_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HDT7735419.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(56427..57059)
                     /locus_tag="RD508_000805"
     CDS             complement(56427..57059)
                     /locus_tag="RD508_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7735420.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(57066..58133)
                     /locus_tag="RD508_000806"
     CDS             complement(57066..58133)
                     /locus_tag="RD508_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7735421.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVETKVPLMKEA"
     gene            complement(58130..58861)
                     /locus_tag="RD508_000807"
     CDS             complement(58130..58861)
                     /locus_tag="RD508_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HDT7735422.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            complement(59029..59508)
                     /gene="greA"
                     /locus_tag="RD508_000808"
     CDS             complement(59029..59508)
                     /gene="greA"
                     /locus_tag="RD508_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDT7735423.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(59644..60819)
                     /gene="mltG"
                     /locus_tag="RD508_000809"
     CDS             complement(59644..60819)
                     /gene="mltG"
                     /locus_tag="RD508_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HDT7735424.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            60984..62144
                     /locus_tag="RD508_000810"
     CDS             60984..62144
                     /locus_tag="RD508_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HDT7735425.1"
                     /translation="MSKGKHRKKQKISISFLVILLLSVSFFSTGIIIGGQLTKIPHSQ
                     TYKAEPTQLTSNLTPDEQRLASKIDQLLQKSDYIGSIYVRKNNRVLLEKGYGYANLRV
                     KESNSPSIYYQIGSIQKAMTALLILKQIQAGKLTFDTKLAEFYPQIPGSQQITIKNML
                     YMRSGLHRTASPDKPMSDSEIIQFALHHLKLTDYDTYHYEPLNYTLLTGILIKLTNQP
                     YETLLKKEIIRPLHLEHTDFYDNVKNSPQHAVSYQMSATDDYSKALIEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGGIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVVAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVHLSN"
BASE COUNT        17964 a        13142 c        10496 g        20668 t
ORIGIN      
        1 ttttgtcaca accttttttg ccgagtaaac ggtgttcaaa agccagtttc tcggtatgaa
       61 gtcaaattta agcaaaaatg tgagaagcta ttttcacaaa atttttcttc atactcgaaa
      121 ctaagcggct ttttcacgac ctctttttta ttttgccatg aacatatcat aatacgcgtc
      181 cattatttct ttagcaatcg tcaagtttat gtggtcttgt tcgtctaata agttcggcaa
      241 gacaacactg atggcaattt ccggattgtc tgttggtccg tatgccacga tattactatt
      301 gactgtcgca atatctggat gaccttccgc aaccgtttct gcagtccctg tttttgcgga
      361 aaggtccatt ttcgcactgg ctaatggttt ggctgttgtg taaggatcgg taccatggac
      421 aacttggtgg aatccttcac ggaggatcgc catattttct gcagaaatat tgaccgtatt
      481 ttctactgtt gtgccaattt ctttcttcac ttcacccaag tttccatttt cgtcattgcc
      541 atagatcgct ttgactaggt gcggctgtac tcgtttcccg ccattagcga ctgttgaagc
      601 atattgagct aattggattg gtgtatatgt gtcaaactgt ccaaatgcca aatcggtaaa
      661 gttacctgga gcataccatt ctttgccatt atccgcattg aacttcttca tataatcaac
      721 agaacgtgag atcccaggag attcattcgg caaatcgatc ccagtcgttg taccaagacc
      781 aaactctttg aaagagtctc tcaattgctg ataagcttta gcttcttcat ctaaactagg
      841 tagtcccatt ccaggtgtat agtctagtcc taacatcttt aacgccactt tgatcatata
      901 cgtattagaa gacaattccg atgctttgac tgcatcaaga gcaacttgtc cgcttcgatt
      961 aaagacagag cttttttctg aagcaccttg cagacgaatc ggctcatcaa tcaaaacttg
     1021 atttccgctg atcgcgttac ttgcccagcc tgctgtcaaa gtaccagcct tgactacaga
     1081 ccctggatca aaggcgctag taatcgtgcc taaagcattc tcggtgattt ctttggaacc
     1141 ttgttcatga ctgaaaccag tcattgctag cacttctcct gtctgaggat tcatagccac
     1201 tgcataagca ccaggcgaat actgtgcttt gccgttgttg atcaatgttt gataattcct
     1261 tttcaaaatt tcttctactt ttgattggaa ttctgcattc atagataaca ttaaattaga
     1321 acctttttcc ccagagaaga tttctttttg attcgaaaca tttccttcat tatcaaggga
     1381 aacttcatat tgggttttgg ttccttgcag gacatcttca tattgttttt ccaaataact
     1441 ttgtcctaca cggtcattcc gagaataacc ttttgctagg tatttctctg cttcatctgc
     1501 tggaagtcct tgcttttcag tcgtcacact gccaagaata cttttcagtg aacttgctgc
     1561 attatattct cgtgtccagt ctgtgccagt cgaaactcct ggaagttcag aagcgcgttc
     1621 tgccacaaca gctaactctt gatcagtaac accagagttt ttgatataga cagtgtttaa
     1681 ttcatatgca ctattcatcc gtttaaagat ggtagcaatt tttaattgct cctcgtttaa
     1741 attaatctca tcagctgtga ctttattgac catcgcacta tattgttcgc tgttccctaa
     1801 ttgcttttct tttgccgaaa gtctttttgt ggcttctttc aaatgtttgg gatcagccag
     1861 ccaaaaatct tttttatctc tatctgtcag attttcatct accggaacat cgatcagcga
     1921 gttcagcttc gttgcgattt caagcaaatc tttagccgta acttgtgttc ctctcgtata
     1981 tgtgatggcc tgattcgctt tattcgtaac taaagctttt cctgtggagt cgtagatcat
     2041 tccgcgagga gtactttctt ggaccgtaat cgtagaagta gacttcactc gcgcctccat
     2101 ctcttcgccg ttcacgatct gcaaataacc caatctagca atcaacgcaa caaataacgt
     2161 aaatataatg aaaaaaagaa aatttaagcg aaaaggaaca tgggaccggc gaaacgtttt
     2221 gttcttaggt tcttgtgcac cttttcttat tttttctaac caagaagtat ttaatatttt
     2281 tttcataaaa tctttcatca tttcctatcc ttccgcctat ttacattcat gcttcattgt
     2341 acccaaaaac ttcttaataa acaagaagta tttaatattt ttttcataaa atctttcatc
     2401 atttcctatc cttccgccta tttacattca tgcttcattg tacccaaaaa cttcttaata
     2461 aaaaagaaaa aatgggcgga gcaagaaatt ctttacctaa tttcaagata aaatcaactt
     2521 tttgtttcac agcaatcact taaagttaca tatccaacta tttttttcat taaaaaataa
     2581 acttattttt gaaaattatg ttttcttaag tcgtgaaaca ctttgatgga tcatttattt
     2641 gtggaaaact acgttttgtt attctaaaaa acttatataa aaaatagtaa ggtttttatt
     2701 tcgaatccat aaaatattct tggattgctt ctcgtgtttt tttcactttt tcgctaagct
     2761 tttcgttttt agccatatag aaataaaaaa tgatatcgat cgtagcaaat tgggccaaaa
     2821 gtgaattagt tgccgcactt cgattcgtga tttcttttgg tctagatgtt tgtacgagta
     2881 catcggctat cttgctaagc gggttatttc caaattgcgt caacgcaatg atttcgatat
     2941 tcatgctttt cgccagctcg gctaatgcga ctacatctgc acttctacct gagtttgaaa
     3001 caagccaaag cactttcttt ttctcattgc tgacaagttg cgggagcaag acgtggatat
     3061 ctttttcaaa aatgattggc ttaccgacac gagaccattt ttgcagaata tcttctacta
     3121 ctaaagaaga ggcgccaacc ccatataaaa aaacagtctc tgccgattcc aaacactcta
     3181 cgactttttg gatcgtttct tcttctagaa tatctactgt ttcttttatc gctacttgtg
     3241 cattgttacc aagtttgttt ttgatagagt aaaaggactc atttgcttct atatcactaa
     3301 aaccttcatc gattccagtc tgtagttctg ttgaaatcgt gattttgaag tccgtcagac
     3361 tttgaaaacc gatttttttg gaaaaacgta caactgtcgg cgcactcaac ccggaagctt
     3421 ctgctaattc attagctgtc attgtaggga ccttctcaat attaccgata atgtagttgg
     3481 ccaacttttt ttctgctgaa gaataatctt ccatcatact ttcaatacga ctaattacgc
     3541 tcataagttc ctccaccctt ttaatgatag tctatgtaag tataccatat cagaccctta
     3601 ttcacggtcg tatactggat aaaaaacaaa aaaacaatcc gcccaacaga atatcttatc
     3661 ccatcaatcc cacagattct attgagcatc tgtgtctttg aggaatacct gttatctatt
     3721 gttcggattg ctttctatct actacttttt tacaggaaat ttacctatta gttttctctg
     3781 ctgtaatttt tgacttctgc ttccatagca tcaataaaga tattcaaatc ttctacagct
     3841 gtttctttac ttccataacg acgtacgttc actgttgcat cttccaattc cttgtctcca
     3901 acaactaatt ggtaagggat cttttgtgtt tgagaggcac gtatcttata gcccattttt
     3961 tcattacgat catcaacttc tacacgcaac cccttcattt gcaaacgttc tttgatttca
     4021 taagcataat cgccatgtgc atcaacagaa acagggatga ttgttgcttg tataggtgcc
     4081 aaccatgttg gaaaagcgcc tttgtatact tctgttaaat aagcgacaaa acgttccatt
     4141 gtagaaacaa ttccgcggtg gataactact ggacgatgcg tattttcccc gtcttctcca
     4201 acatatgtca aatcaaagcg ctctggcaat aagaagtcta attgtatagt tgataatgtt
     4261 tcttctgtac caagagctgt tttgacttga acatctagtt ttggtccgta aaaggctgcc
     4321 tcgccttctg cttcaaagta atctagttct aattcatcca tagcggcttt cagcattgct
     4381 tgggcttttt cccacattgc gtcatcatca aaatatttat ctgtattgtt tggatcgcga
     4441 tagctcaagc ggaaacgata atctgtaata ttgaagtcag catatactgc caccatcaat
     4501 tcaagcgtac gtttaaattc atctttgatt tgatcaggac gaacaaatgt atgaccatca
     4561 ttcaacgtca tttctcgtac acgttgtaaa cctgacaaag cacctgattt ttcatagcga
     4621 tgcatcattc ctaattcagc gatacgaatt ggtaattcac gataagaatg gatcgtgttt
     4681 ttgtagacca tcatgtgatg agggcagttc attggacgaa gaacaagcat ttcgccatct
     4741 cccatatcca ttggcgggaa catgtcttct tgataatgat cccagtgtcc agatgttttg
     4801 tacaactcaa catctcccat tattggtgta tatacatgtt ggtaacctag actaacttct
     4861 ttgtctacga tataacgttc gatcgtgcgt cggattgttg ccccttttgg aagccagaat
     4921 ggcaaaccag aacctacttc tggggaaacc atgaacaagt caagttcttt tcctagttta
     4981 cgatggtctc tttcttttgc ttcttcacgg agacggatat attctttcaa agctttcttg
     5041 tcaaaaaagg ctgtcccgta tacacgttgc atcatttgat tgtttgagtt tccacgccaa
     5101 taagcacctg ccactgataa taatttaaat acttgtatac ggccagtgga tggaacatgt
     5161 ggtccacgac acaaatcgat gaattcgcct tgttgataag cagtaatcac ttcttcttct
     5221 ggcaattcac taatcagttc tactttgtac ggatcacttg caaaaatttc taatgcttcc
     5281 tgttttgaaa gaacacggcg ttcgattggc agattttctt tgacgatttt catcatttct
     5341 gcttcgattg ccggcaaatc ttctgcagtt acttggtttt gtccattatc tgtatcgtag
     5401 taaaaccctg aatcgatagc tggtccaacg ccaaagtgga tatttggata gaggcgacgc
     5461 atggcttggg ccatcaaatg agctgctgaa tgacggacta agccaagtgc atcttcatgg
     5521 tctggtgtga tgatctcaat acttgcatct tcctcgattg gacgagtcaa atcaacgagt
     5581 tttccgttca ctttaccagc taaagctttt tttgctaagc tttttgaaat gctttcagca
     5641 attgccaatg ttgttgttcc agactcaaat tctttgactg caccatctgg aaaagtaatt
     5701 tttatcataa tagtttcctc cttgaaatgt tttgattgat cagatcatca agctgaaaaa
     5761 caaaaaaatc ctagcatctc ttgaaaagag atactaggac gaaaagttcg tggttccacc
     5821 taatgttcaa acgcaaatgc gttcctcaag cgttgtaacg gtccgaccgc ccttgcttca
     5881 acaagggttt cgaaagtggt catcctttgg ttttctcctg gaaaagtttc agcctagctt
     5941 ttcctctctt atcgaagact ctcaaattca gttggctttc tcatcaatca attatgtgtt
     6001 tatttaacca ctaataaata gaaaaatcaa gtgggaaact aaacttattt tttccattcc
     6061 ccatttacac cgtatgttcc ttttttcatc tcattgatga tgacatggat gtgttctttt
     6121 ggtgcctgcg tgtttttatg aacagcttcc gtgatatctt tcatcatatt ttctaattgt
     6181 tccggactgc gaccttctac taattcgaca tgtacgaatg gcataatgct ctctcctctt
     6241 tctgatcgtt cttttttcaa ctcgattcta tcatactatg tttgtcttgg gtactgaatc
     6301 aggaaaaatg gctggatctt tttttgctct caaggcactc aaaatagaga ccgtatccac
     6361 gacttcttgc aaaacagctc cgaataatgc ggggattagt cccgtacttg caattaacat
     6421 caaaaaaata caaataaaga tgccaatcag tacagactgt ttagctattc tcatcgtatc
     6481 tcttgaaatc actactgctt ttgctacacg caagagatca tctttcaaga tgaccgcatc
     6541 tgcactttca ctagcagctg tagaaccatg agcccccatt gcaataccga tatctgcagc
     6601 agcaagtgct ggagcgtcat tcacgccgtc tcctaccatc gcaacaggtc tttgatcttt
     6661 agggatactt tctaaaatgg tcagtttatc ttgaggcaag ctacgggcat gtacagaatc
     6721 taattggact ttttctgcaa tcgtttgagc aatggcagat ccatccccgg tgatcatcat
     6781 caaatttttc acatcaagtt ttcttagctc cttgattgtc tttgctgctt ctgggcgaat
     6841 ctgatccgaa aataggatcg ttcctgcaaa agatcgatca attgttacat agattgctgt
     6901 attggacgtt tctatttctt cagctgaaac aaaagaggca cgtccaatct ttacttcatg
     6961 attattgact actgcttgga ttccttgacc ggtcacttct ttcagttgac taacaggata
     7021 cagttggctg tttttcacgt tgttcactaa cgaacgagct aagatatggc tagattcctg
     7081 ttctgcacta gctgcataca gaagtagctc ttcttttttt actccattga ctggctgaat
     7141 cgcctctact tccaatatcc ctttggtaag cgttcctgtt ttatcaaaag caatcgtttt
     7201 tgtacgtgcg agcttttcaa tcgttgttcc agtttttaca acgatcccgt ttttacttga
     7261 acggctcatt cctgcaacta aagcaatggg cgcagctaga atcagtggac aaggtgatgc
     7321 cactaccagt acctcagcaa atcgtaaagg gtcttttgag aaccaccaag aaataccacc
     7381 gatcaaataa gcaatcaacg tgaaagggac tgcataacga tcagctaaac ggacaaatcg
     7441 ggcaggcttt tcttttgatt cttcgactag tttaataatc atttgatact ggctgtctgc
     7501 ggcacgtttt tcagcgatca tttggatcga tccgtctcca tttaaagacc ctgacataat
     7561 ctgatctcca ggtttcttgg tttccgggcg ggactcacct gtcaaagaag attcatcgac
     7621 cgaagattct cctttggtca ctcgaccatc tgcgggtaca agttcgccag gcttgactag
     7681 taactgatca tcaatattta tttcatcgat tactatatcc tgcaattttc cttctttgaa
     7741 tcgatgggca attcttgggg tgttatctaa caaagactgc agttctttac ccgctcgttt
     7801 attcgcgtaa tcctctagac tatctccgcc cgtaagcatg atcaatatca tcaaactagc
     7861 ccagtattct ttgacggcta atgttgcaag gattgcggta atcgctaata catctacgcc
     7921 atatcttcct gaacgtaacg tcttgatcat ttccaaaaac atcaagaagg cgagaatccc
     7981 tccagtaaat gcgacaatcg caaatgcaag ggccggctgg tgaaaaacaa attcacttaa
     8041 taaagctatc ccaccaataa gcaaagtaag taaaaatttt ttgaaatgtg tcattgtttt
     8101 ttctcctctt ttatgtaact tagagaggtt agtaataaat ttccagctgc ctctttcatc
     8161 ttaagcatag tccttgacta gcacttttta aaacaatagg ccttaattga aaacaactat
     8221 cactatcagc gtttccaaaa ttcatcagtt ctacaaacaa aaatattcag caaggattac
     8281 tttttcgatt catcagttaa aaagtacctt ttttcgaaaa actatgctat acttttaatt
     8341 cgttatttac ggcggaagga gcaaacatgc gatgaatgag aaacaactag aacaaacgca
     8401 cgtggatgaa acgatcgaac taatccagat cgaacaaaat atgctggata caaaacaaca
     8461 agaattgact caggaaatga atcattcgac aaaagacaca gctaatcaca agattcgagc
     8521 tggttccaat gaagcttttt atgaatctgc tgttgaatat cgccaacatg agcaggaatt
     8581 gcttttgaaa taccatactc ttgaagcaca gcaaaaacgc ctgcaaacgt tgtctgtcat
     8641 gaaagatagt ccttattttg cccgtatcga ctttaaagaa gaccgtgaaa cagaaacatt
     8701 atatctaggt atcgcttctt taagagatct ggcagaagaa acaatcgtta ttgactggcg
     8761 tgcaccaatt gccaatcttt attatgaagg tgagattggt cccgcatttt atgaaactga
     8821 aatagataga atagatgtcg atctgcagtt gaaacgacaa tttaaaatcc aagaaggtcg
     8881 tattttatct atggtagata cgtcggaagt aatcaatgat gactttttgc tagagatatt
     8941 ggatgaatca tcaagcaacc atatgaaaaa catcgtctct acgatacaaa aagcacaaaa
     9001 tgcaatcatt cgggacacaa caagtaaagt aatgctgatt gaaggaatcg ccggaagtgg
     9061 aaagacatcc gctttgcttc aacgtattgc ttttctgttg tatcataatc gcaagtggct
     9121 cgaggctgaa aacgttcttc tattttcacc caaccatttg ttttctgatt acatctcgac
     9181 tgtattgcct tcattaggtg aaagcggcgt gcctacacag acattcaaaa attatttggt
     9241 gcagctgctg ccagagtttt ctttactaga tgaacagcaa caagaaagtg gttttttgct
     9301 aggggaaaaa gatccgatac aagtgatgaa aagcggattg accttagtcg atcagattga
     9361 tcgctatatc caaggcatca caaactacgg tcccttgttc cgtgatatga aaataaatgg
     9421 ccgtacgatc ctatcaaagg aatcgattcg ccaatggtat aaagaaacaa atgaacaatt
     9481 gcctttacat catagactct ctctattaca aacgaagctc ctgaaaaaat taggcggtct
     9541 gcaaaaagac gaaacacgtc agcaatgggt caaagatctg gcggaagaac agctccaaga
     9601 actatacgca acagatccaa atcttgaata tacagaacaa aaggagcgtt cattacgtaa
     9661 aaaactggcc aaccaaatcg tacgtaaaag attccgtcga atccatcgag ggatcatgaa
     9721 ttatcaattt gtcaatataa cgaaacaata tctccacttt ctacaaactg tgccactttc
     9781 tcttctaaca cgacataaaa tcagcgagac cagatggcag gaacatttga caactgttcg
     9841 tacacacttg cgtcaaagag aattgcgtca agaggatgct gtactattct ttttactgat
     9901 gcgccgaaca tatccagtga cggttacaca caaagctcgc tatatcttta ttgatgaaat
     9961 gcaggatttc gcaccatcac aagtggcatt gctgcaagcc ttgttcccaa aagcaaattt
    10021 gactttctgt ggagatctaa atcaaaatgt ctttggaaat gaaacgatcg ttggatcatt
    10081 ggaagacctt ttcgtggacc gtgaagtcac tcgtttccaa ttaacgacaa gctatcgctc
    10141 cacaaaagaa atcactgatt ttgctaatca ttttattgtg aaagaacatc aagtagaaac
    10201 aacagcaaga aaaggagacc ttcctttgct catccaagga acaacagatg atatcaaatt
    10261 gaattggtta gcagatacca ttcgaacgac tcagggaaaa gcccggtatt ggcgtacagc
    10321 aatcatagct aaaacacaag aagaatgcga agctctttat gctcaactgc cagacgagtt
    10381 gaaacaacaa gtccagctga ttttaaatga gagtgacttt atgaaacgtt ccattatttt
    10441 acttccagcc tttttagcaa aaggtctgga gtttgaccga gttttcttgt gggatgtaga
    10501 tgcagaacat ttttcttctc agcaagacaa attgatcctt tacaccatgt gtacacgtgc
    10561 gatgcatgaa ttgacccttt ttacctccaa taatgaaagt cctttgttaa acaatatgga
    10621 tatttcatct tatgagaaaa aagtactgta agtaaaaaga caactgctat cattaatgtt
    10681 agcagttgtc tttttattta caataataat tgcagaaaaa gtaattcaat catttaaggt
    10741 catttattct atatataaat ccaaatctgt ttcaggatat tttaatttga caagcgaaat
    10801 aatcattttc agttcttcca tgttttctgg atattctggg tcaaatacct tgctatgacg
    10861 gccaatcccg ccattgtcga tcaatcggta aattcgattc cattcaatga attggtcaat
    10921 tgattggaaa ttgctgattg gatagccgcc acaatccaaa atctctgata cacgaaatgc
    10981 taggtatgca ctatcgatca cattattttt tttcgtgtct atcttctcat ttctttcgat
    11041 aagaattttt tcaggacgat gcttcaagct ccactctaat agtagaaaga aagcctccat
    11101 ccgatactct tcttcaaata accgaaaggc tgaatcagaa cgacgaaaaa gcagcggaat
    11161 cagataattt tgtctataaa tcagcattgg tgcgcggtcc accatacact ctaaataacg
    11221 gttcagatac cctgtaccga catagtttcc taatcgatag ccttcaacgc cgaatcttgc
    11281 gtatttttgc gctaattttg aacaatcagt tacgttcaca gctaactctt ctactttgcg
    11341 gtaaccgctt aagatacgtt caaaaggttc taaagtgatt tttgcttcca tattcttccc
    11401 cgtccatctt ccacatactt catatcattt cacatgatac ttatgctctc atcataccac
    11461 aggttgaatt agaaaagaaa ataaatcaca caaaaaagca agacaatctg ttagtgagat
    11521 tgtcttgctt ttcgaaaaag actgaatact tttcgttaaa actggttgct tagtcttcta
    11581 atgccacatt atggaacaca tgctgtacat cttctagatc ttccagtgca tcaatcattt
    11641 tttcaaatgt ttcttgatct tctggagata gtgttacctc gttttgaggg atcatttgga
    11701 tctcagcgat tgaaaaatca gtgattcctt tttcttttaa tgcttcttgt atactatgga
    11761 aatccgctac ttcaccgtaa acgatgattt gtccttcttc ttccattaca tcgcgaacat
    11821 cgatgtcttt ttccattagg tattcaagga tctcgtcagc gtcttctcct gcaaaagcaa
    11881 agattgctgt attgtcaaac atgtaagaaa ccgctccgga aacacccatg ttcccgccat
    11941 ttttcccaaa tgctgcccgt acgtctgctg ctgttcgatt cacattgttc gtcaatgtat
    12001 caacaatcac cattgagccg cttggtccaa atccttcata gcgcaattca gagtatgttt
    12061 catctcctgc accttttgct ttttcgattg ctcggtcaat aatatgtttt ggtacattat
    12121 aagttttagc gcgatcaatg acgaaacgta gtttttggtt tgcatgcgga tcaggatcac
    12181 ctgattttgc tgccgcgtag atttcaatcc caaattttgc ataaatccgg ctattattag
    12241 catctttagc agttttcttt gctacgatat ttgcccattt acgtcccata ttttcacttc
    12301 gctttctgat ttgatagttt cataacgcaa aaacgtcctg ttccattata cttgtgaatc
    12361 acgattctgt gaagcttttt ttctttcttc cttcattctt ctcattttta gtcaattatc
    12421 tatactcgga ttgggatttg cccgaaattc tgttccggaa tattgcctcc caattgatag
    12481 atttgatcac ttctaactaa cagttccgct tcttgtgcct ctttttttcc gattcgggaa
    12541 taaatagaaa tctctttttt ttcttttaag aatcttcttc caacatcggt aaatccaagt
    12601 agtcgaagat aatttttatt ttgttggaca ggaatctctt gctttttgat attcagcaag
    12661 acataacaag ataatcgttg gatccgtgtc catgtatatc tttttgtttt tacctttgac
    12721 acaaaatcct caaaactatc agcagttgca gctgctgttt tcatgcgcga ttctattcct
    12781 tcggtcatct gatagatatc tgtcagttcc agcaaagtag aagataacaa ccgataacgc
    12841 aaatacggcc aataagattc ccaagtctgc agcgaataag ttgaaagatc ttcttctgtc
    12901 tgaggcggca caagtccagc tattcttttt ccttcttcta acgcatggcg aatggctgtt
    12961 gcactggcta tcctctgatc tgtgatgatt ttttcatgat agcctgcact tttacgtcgg
    13021 atcggatgta attccatagg gtggacatac ttggcatttt cctttgcata acttaatccc
    13081 aagatatgat ttggcgaaga aaaatcaagc gtaatatcgg gatacagact gcgaaaaacc
    13141 tcagtcattt tttgcggata actatacgtt tgatcagaca gttcttgaaa tgcctcttct
    13201 atcctatctt gattctcttg gacaaagcgt ccgaaactgc tgtaatcaaa cgaagtctct
    13261 tcttctgttc caaaacacaa actgtcacag tccagtgttt gcaagatttt tactgcacct
    13321 ttagcaaaat agtcagctga ctgaaccgcc cattcgacgg gaagctccac tactaaatcc
    13381 acaccatttt gtaaagcttc attcgcgcga tgccatttat cgatgatagc cggttcgcct
    13441 cgttgcaaaa aattcccgct cattacagca atgacgacct ctgctcctgt tgtttttcgt
    13501 gccatttcca catgatagcg atgtccattg tgaaaaggat tgtactctac gataatcccg
    13561 cagcttttca tgcgcatcct ccttcatagt tatcgataaa aaagaaatag agacaagtaa
    13621 aaaaaggcaa aaatcggaaa aaatacccga actatataaa ctattctcgc aaacacaata
    13681 cttctgcgac gaaaagctgc actgcaagag caatgcctat atcgttcgga tatataattt
    13741 atgttgaaga tttattcttt tcttgttaac tcgagcaggc aaaaccgcta gtctttgtat
    13801 gctacaaaga accagcgctt tgatttctct gatgctgctt cgtctgtaaa atcagaaaat
    13861 gcttcgactt tcgaaaagcc gctgttttcc agcattctta aataactttc caatggatag
    13921 gtacgctctt gatgtagttc atcttcacga ataaatcgac cagacccttc ttgttcttca
    13981 acgaaaaagg taagaaaatg ttcgatgctg tgtttctcgc ttcctggata actatcccac
    14041 aaaaaagcaa aattatcccc ttgataatga tagctatatt ctggaaaaat ttcatctact
    14101 tgataggtgg agtgtacgtc aaataaaaat cggccatttt cttctaacgc ttgatagact
    14161 tcatcaaaca cttgctgtac ctcttgtcta tttttcatat agcacagcga atcagaaaaa
    14221 caggtaattg cctgatattg tccgatttct gataaatcga gcatattgcc ttccacaaat
    14281 tggatcgatg cgtcttcttc atatgctcgc tggctggcaa tcatcaacat ctcttctgaa
    14341 aggtctaacc ctgtcacttt atatccatct tttgcaaagg caactgctaa tgctccagta
    14401 ccgcatgcca gttccaaaat attttttgtg tcttcttgta aatgacgttt cgaaaaagct
    14461 agccattgct gataaagtgt ttcgtccatc acttcatcgt aaatgaaagc aaatgtttca
    14521 taagccatat gttaatccaa ccattcacta agatcgacta gcggagcatc tgaccatagt
    14581 ttttccagat tatagaaact tcgttctggt gcatggaaaa catgtacgat cacatctcca
    14641 agatcgatca atacccattt tccgccttct tttccttcaa tacgttttac ttcatatttg
    14701 ttttcttctt ctttatcaat gatttcttct gtaattgcgt tgatttgacg ttcgctattt
    14761 gctgaacaga tcatgaaata atctgccaac aaggaaacat ttcgaatgtc taaagcgata
    14821 atgtcttctg cccgttttga atctgctgct tcaaccgcaa tttttaattg ttctttacta
    14881 tctatgatga tttcctccta atatgagcag cttatttttt tgctacccag taattatatg
    14941 tttcgattgt ttttggataa atctgttgtt cttgcgcaag caaatgggcc aatgtatgtt
    15001 ttgtttcaaa tgctacagct tcgtctagat cagcccatgc aatggctcgt gcatcttgta
    15061 ccccaggaaa atctcgacct ggttcaatat agtctgctac ataaatgatt ttgtcaagga
    15121 gactcatctt agcagcccca gtcgtatgca cccggattgc atgaagaatt tctgcatcgg
    15181 tgattcctaa ttcccgctct acaaacgaag cgccaacaag accatgccag attgcattat
    15241 tataattcaa taactctgga tcaaaaccgt ctcttacgat taccattttg aactcctcat
    15301 ctggtcgttc ttttgcataa tcatgtgtca atgcagcaat actagctttt tcaggagaag
    15361 caccgtattt tttggcaaga gccacggctg tttcttctac tccaagcaca tgcttgaagc
    15421 gttgttcgct cattctcatc tgtatttttt gcatcaggtt ttctctagaa taagcagtat
    15481 attcattact atagtccata ttcatacaac ccttcatttt gaatataatc aattacttta
    15541 tctggaacaa ggtagcggat agaacagcct tctttgatct tttgacgtat tttcgtggaa
    15601 ctgatgtcga tctcaggtac atctacccaa attacaggat atggagtatc cgttgtgtat
    15661 cctggtcgac gtatacccac aaagttgacc atagaagtca gctcatcgat tttataccat
    15721 tttggcaaat attctaccat atccccaccg ataataaagt aataatctgt atccggattg
    15781 ttttgcgtca attccttcat agtatcatag gtgtaacttt tcccaccacg agctaattca
    15841 atcgtttcaa tctgcaaaaa aggattgtct tccacagcta attccaacat gttgagtcga
    15901 tgttttgcat caatcgtctg tttctcatca acatgaggtg gctgataaga aggcatcaaa
    15961 aatacgcggt caagacctaa attccggcca gcttgttcag ccatcactaa atgtgcaagg
    16021 tgaacgggat tgaatgttcc gcccaagatc cctacttgct ttttcttctc taagaattga
    16081 ggcatttctt caggaaataa ttgtgaacga acaaatgtct tagcttgcgt attcatcatg
    16141 gtcactcctt atattgcttt tacttctttt gatagccttt gatacttttc ttttgtggaa
    16201 ggtttgtata atacaataac acgtccaatg atttggacga tttcgcaatc tatttctttt
    16261 tctaatactt gagctgcttc ttctgcaatc tcatctgtat tttgaagtaa cgatactttg
    16321 atcagttctc ttttttctaa agcttcttca atttgaacga tcattgctga attgatccca
    16381 ccttttccga tttgaaaaat cggctgaaga tgatgcgctt tgctacgtaa aaaacgcttt
    16441 tgttttcctc ttaaactcat aattttcctt cttccttaaa tcaatgcttt gcgtttcaat
    16501 acatctacac cctttggcgc ccagcccgca attactactg gcgctgttac agtgatccag
    16561 cctagaccgg caaaaacgat gtctgttttt tctttcacag aaaactcaaa acgaacaagc
    16621 tccggaaatg cctcgacttc atcaggacga ggaggctgta ataatccacc tacatgtttt
    16681 tgataaaatt cgtctgcttt ttccagtttc gttcgatgaa tatttacatc atttgacaca
    16741 taagcaataa atgaagcacg attgccgctg ataaaatcaa atcttgcaag tccgcccaag
    16801 aaaagtgttt gcccttcatt cagctgataa actttaggtt tgatttcttt taacggtgca
    16861 atgatccgca aatctttttt acctaagtag tgcgccattt gatggcgatg gataattccc
    16921 ggtgtatcaa tcaaaaaatg cccgtcatct aaaggaatct cgattttatc caaggtcgtt
    16981 cctggaaact gcgaagttgt gattacatct tgtactcccg ctgtattttt gatgatttga
    17041 ttgataagcg tcgattttcc gacatttgtt actccgacga tatagacatc ccgtccatcg
    17101 cggtattctt cgattttttc taatagttcc gtcatctcat gagatttctt agcactagtt
    17161 aataatacat ctactggacg aattcctgct tcgtaagcac gttccttcat ccattgtgtt
    17221 aatttagttt ttttcaatga tttaggtaat atatccactt tgttcccaac taaaagtact
    17281 ggattgtcac cgacaaaacg gtgtagtcct gggattagtg aaccattgaa gtcaaaaata
    17341 tccaccacat tgacgatcaa tgcatctttc tgccctaatt cattcagtaa gcgcaaaaag
    17401 tcgtcatccg ttaatgagac atcttggatc tcattataat ggcgtaatct gaaacaacgc
    17461 tgacaataga cttccccgga agctaaacct ttttccaaag ccgtttgcgg cgtgtatcct
    17521 aattcaccgg gtttgtttgt ttgtataacg gcaccacagc cgatacattg taattcttct
    17581 gtcattcgat tccacctcgc cagcccatat cagggtgttt tgctaataga taggccataa
    17641 ttcttttttc ccaaaaacga ttaaattgtg tcttccaact atctgttgcg ataatgggtt
    17701 ttacaaggat gctacgtatc cctgcacgat tggctccacg tatatcagtc ataatctgat
    17761 cgcctaccat tactatctca tcatctgcta aatccaattg tttctttgct atgttgatcc
    17821 ctcttgctaa aggtttcatt gctcgtgcaa catacaaaag atcaaatttt tcaatcgctc
    17881 gcgcgacacg ttttgaatta ttgtttgaaa caacaacaac agggattcct gcatttttca
    17941 tttctaaaat ccaagtaagc aactcttctg ttccatctgg attattccat gcaatcaacg
    18001 tattgtctaa atcggtcaat actgctttga tgcctagatt ctttaattgg gcaggtgtaa
    18061 tctgatagat ggcttctacc atccatgttg gtttgtaatt tgaaaacatg ctgtctcctc
    18121 atctgcaaaa aatgaaggag cacataaagt actcctcaac cccgtattat actgcatatc
    18181 agcaaaaaaa actacctcta tactcgttcg tctttcagaa aaagcatttc tttacaaaat
    18241 gaccaaaaat aaagattgat cacagaaaaa tttagaaaca aaaaacaact aagcgagcaa
    18301 gaccattctt tactctttgc ttagttgtta aacacctaat attggcggaa cctcttgtat
    18361 cgtttttcca gtaattcatg ctggtcgaat cgaacaagtt ccgtcaatct ttcaatcaac
    18421 gcttttttca taatgtgtgc gactttatat cgtggcaact gctcgccgtt gaacgtttca
    18481 ggaataactc gatcaacgat tcctaactcg cgtagttctg gcgcagtaat tttcatcaac
    18541 tcagctgctt ctgcggcgcg actaccgtct ttccacaaaa tcgacgcaaa tccttctgga
    18601 gaaagcacag cataaatcgt ttcttccagc atccagactt catccgctaa acctagagca
    18661 agggcaccgc cacttccacc ttcaccaatg atgatggcga tgatcggtac ctttaaatca
    18721 gacatttcga gcagatttct ggcaatagcc tctccttcgc cgcgctcttc tgctcctaca
    18781 ccgcaatatg cacctgctgt attgatcaat gtaatcaccg gtctattgaa cttttccgct
    18841 tgtttcatca gtcgtaaagc ttttcgatag ccttcaggat ggggagaacc aaaatttctg
    18901 cggatatttt cctgcagatc ccgtcctttt tgaataccga tcactgttac cggtttgcca
    18961 tctaatcgag cgattccacc aacaatcgct tcgtcatctg caaacaaacg atcaccatgg
    19021 cattcctcga aagaatcgaa gatctcttca aaaaaatcca agcttgtcca tcgttcttta
    19081 gctcttgcta actgaacgac atcatgtgct gtcttatcca cgatctatcc atcctttctg
    19141 tgtatgcaat tcaagaagca tatggatttt ctgcttcaat tccatgcggg gaacaatctg
    19201 atcgacaaaa ccatgagata ataagaattc agccttttgg aaatcttctg gaagttcctg
    19261 cttgatcgtc tgttcgatga cgcgtcttcc agcaaaaccg atcaagcttt ggggttctgc
    19321 tagaatgata tcgccttcca ttgcaaaact ggcagttact cctccggtcg tcgggtccgt
    19381 taaaacagtt agataaaaaa gaccttcatt gctatgccgt ttgacagcag cagagatttt
    19441 tgccatctgc attagagaaa agattccttc ttgcatccgt gcgccacctg aagctgtgaa
    19501 caagacgact ggaagacttt cctttgttgc tcgttcgaat aatctggtga tcttttctcc
    19561 gacaatcgtt cccatacttc ccatgataaa attaggatcc atcactccaa taatgaaggg
    19621 aatcccttga atggttgctt taccagtgag gactgcttca tgaagtcctg ttttatcttg
    19681 cattttttta attttttccg tatattcggg aaatgctagc ggatctttgg ttacaagatc
    19741 cgtatcccat tcttcaaaac ttttttcatc aataatcaaa gctagacgct gccatgcacc
    19801 gattcgaaaa gcgtatccgc aatgagggca tactttttct tcaccgatgt ctttcgtata
    19861 aaggatatgt ttgcaatttg gacactttgc ccacatgtta tcaggaacag atggcgagtt
    19921 agcaggtttg ctctctctat taggattgat ccgaatatat ttctttttct taaacagagc
    19981 catctatgcg cctcctatct ccgtttctgg tgtccaattc ggtaaaaatt cttcttgtaa
    20041 aaatgctgtg ctgtaatcac ctgctatgac tgcagggtga ctaatcaaat ccatctgaaa
    20101 ttctgcgttc gtgatgattc cttctgtgat aaattcactt aaggctcgct gcatcttcat
    20161 taatgcttca aaacgcgtat ttccatggac gattattttt gcaatcattg aatcataata
    20221 tggcgggatc gtatatcccg ggtaaactgc actgtctacc cgcagtccca tcccacctgc
    20281 tggaagcagt aagttttgga tcttccctgg agaaggagca aaatggaaag caggattttc
    20341 tgcattaatc cggcattcga ttgcgtgtcc ttggaatact acttcttctt gacacacatt
    20401 caaaggctca ccggctgcta tctccacctg tttttttact aaatcgattc ctgtgaccat
    20461 ttctgttact ggatgttcca cttggattcg agtattcatt tccatgaaat aaaaatcgcc
    20521 ttcttcatcc atcagaaact cgatcgttcc ggcattttca taattgactg ctttagctgc
    20581 tcgaacagca gcgtctccta gtgcttctct ttttgtttgt gagatcacta cagaaggaga
    20641 ttcttccagt actttttgat tattacgttg caaagaacaa tctcgttctc ctaaatgaat
    20701 gacattgcca aaatgatcac ctaaaatctg aacttctata tggcgagtag gataaatgat
    20761 tttttccaaa tacatatcat catttccaaa tgccgctgct gcttcttgct gagctgaaga
    20821 aaaatgctgt gggagctctt cttttgattg aactttccga atgcctttcc cgccaccacc
    20881 tgcagctgct ttcagcatca ctggataacc aattctgtct gctatttcca atgcttcttc
    20941 tactgtagat aatacaccag tacttcctgg aatgactggg acatttgctt cttgcatcaa
    21001 ttgacgcgca ttgatcttat ttcccattgc atcgatcgtt gcacttttag gaccaataaa
    21061 tgtgatattg cactcttcac acatggaggc aaatcggcta ttttcagata aaaaaccaaa
    21121 tcctggatga attgcttcgg cttttgtcac gattgcagcg ctcagtactt cctgaacatt
    21181 cagatatgaa tcaacggctt ttgccgggcc aatgcagatt gcttcatctg ctaactgtgt
    21241 atgaagtgct tcggcatctg cttctgaata tatcgctacg gtttggatcc ctagttcgcg
    21301 gcatgcacga atgatacgta cagcgatttc accgcggtta gctatcaata ctttagaaaa
    21361 catatttcac ctatccaatc ataaaggtta attccgcttc ggctactttt ttaccgtcta
    21421 ctttagcgat tcctttgcct attccggctg aagctttcac tttcaatatc tcaacttcaa
    21481 ggtataaggt atctcccggt gtaactttct tacggaattt tgctttgtcc aatccgccga
    21541 aataagccgt ctttcccttg aattgttcaa gagaaagtaa tgcaactgct cctgcttgag
    21601 ccatcgcttc aacaattaat acccctggca taacaggttc ttctggaaaa tgtccttgaa
    21661 aaaagggctc attgatcgtt acatttttct tagcaacgat ccgttctcct tcaaccattt
    21721 cttccactcg atcaatcaaa agcattggat aacgatgtgg aatgatttct tttatttctt
    21781 gtatgttcat tgatttccct ctttcctgct ttgcttattt ttgctgaatc ctaaagagtg
    21841 gctgtccata ttcgacaact gactcgtttt ctacaaggat ttctgtgatc actccgtcgg
    21901 cctcactagt tatctcattc atcagtttca tcgcttcaat aatgcagata acttctcctt
    21961 tggcaacttg atcacctact tttttgaaag ctggtttgtc gggcgccggt tgcagataaa
    22021 cgattcccac gattggcgaa acaacctcga ttccatcaaa tactgccgat tctttttctt
    22081 tcattgtttc tggagcagtt gttgcttgtt caggtatgac attgactggc tccgaaactg
    22141 gcaacgtttc gtttgtttga accatattca tgcctcgact tgttttattt ttattcatat
    22201 acaattcaaa ttgaccttca cgcaaatcga attccgttag cgaggattga tcaaattgac
    22261 tgactaattc tctgatttca ttgatatcca aaattattcc tcccagcgtt tcatgcacag
    22321 aaccgcatta tgtccgccaa accctaatga attactcatt gcataagtaa aacttgcagg
    22381 tttgctttcg tttttgacaa ctgtcaagtc aatctcagga tcttgttttt ctacattgat
    22441 cgtaggtggg ataaattgat gttctaatgc cagcaaagtt gccaaggctt cgatcccgcc
    22501 ggctgctccc aataaatgtc cagtcatcga tttcgtgctg ctgacgtaag tatctctgaa
    22561 attttcacct aatgcgattt ggattgcttt tgcttctgcc tggtcattgg ctggtgtact
    22621 tgttccgtga gcattgatat atccgacttg ttccggctgt acaccagctt cttccatcgc
    22681 aagcttcatt gctttagacg caccagaacc atctggagta ggagctgtca tatggtaagc
    22741 gtcacagttt gcaccgtatc caatgatttc tccatagatt ttggcaccgc gagcttgtgc
    22801 atgttctaaa gattcaagaa ctagaacacc tgctccttca cccatcacaa aaccatttcg
    22861 attttcgtca aacggaatcg aaccacgatt aggatcagtt gattctgaga gtgctgttaa
    22921 agctgcaaat ccagcaatcc ccatctcaca aatcgttgct tctgttcctc cagcaagaat
    22981 gacatcagaa tagccatgtt tgatgttacg gaatgcttcc ccaattgaat tcgttccgct
    23041 agcacaagct gttacgatag ctgtacaaat accttttgca cctacgcgca aagcaatatt
    23101 tccagctgcc atgttggcaa tcgccattgg tacgaacatt ggagaaactc gttttgcacc
    23161 tttttcatgt agacgaataa cttggttttc gattgttgga agaccaccga tcccagatcc
    23221 gatgatgacg ccaaaccggt cttgattcat tttttcttta tctaaaccgc tcatctccat
    23281 tgcttctaaa gcagcgtaga ttccatagat cgaaaacata tccattcgtt tgctatcttt
    23341 tttaataaaa tatttatcgt aagggaaatc tttgacttca cccgctaagg taatccctgt
    23401 ttctgaagca tcaaatttag tgatcggtgc gatgccattc gtcccctctt ttaagctatt
    23461 caaaaagctg tctgcgtcat ttccaatagg tgaagtgact ccatagccag taattaccac
    23521 tcgattcatt tgtttgctct ccttttctta tccgtgcatg accaatccgc catcgacatt
    23581 gatgacttgt ccggtgatat atggattttg tgctaagaaa actgctgttt gtgcaatatc
    23641 ttctacttgt ccgaaacgct gcatcggaat ttgcttttcc gcttgttcct tgactttgtc
    23701 tgctaaaact tccgtcatat cagttgtgat gaatcctggc gcaatggcat tacatgtaat
    23761 gcctctagtt gcagcttctc gtgccacaga ttttgttaat cctactacgc cagctttact
    23821 agctgcataa tttgcctgac caatatttcc aatcaaccca gatacactag agagattaat
    23881 gatggcccct tctcgctgct tcatcatttt tttcaatacg tgctgcgtca tattgaaggt
    23941 tccaatcaaa ttgatatcaa gacatttttt gaaatcttct gcatccattc gcatcacaag
    24001 tttgtcattt gtgattccgg cattgtttac taacacatgg atcgatccaa gcttttcttc
    24061 tgcttctttg atcatttgtc ccgctttctc ataatcagag atgtcaccgg aaactcctac
    24121 gcattttaca ccgaatgctt cgatttcttc tatcttttct tttggaatct ctccgcgacc
    24181 attcaaaatg atatttgctc cagcttttgc aaaagctaag gccatcgctt tgccgattcc
    24241 tcttgtacta cctgtgataa atacattttt tccttttaca tccataacgt tcctccttat
    24301 agtattgcta ttgtttcatc aaatgtctgc ttattctcaa cacgcagaac tggtattgtt
    24361 ttatcgattt ttttcataaa tccgcttaat acttttccgg ggccgacttc gatgacttgt
    24421 tcgatgccga ttgtttttaa cttatggata ctctcataga aacgaacagg ttgcatgact
    24481 tgctgttcaa gtagtcccgc gattgtttct ttcttcatta tttccgttgt tgtgttgctt
    24541 atgataggaa aagaaggttc agagaattga atctgactta ggtccttcgc cagttttttt
    24601 gctgccggtt ctaaaatagc tgtatgaaaa ggcccgctga catttagagg gatcattctt
    24661 ttgaaccctt tttcttttaa tagtaaaaca gcttcgtcta ctgctttttc ttcgccacca
    24721 atcacgatct gctgaggtgt attataattt gcaggagata cgatgccgta cttgctagct
    24781 tcatgacagc tttcctcgat cgtttcaatc ggcgcattca tcactgcaac cattttcccg
    24841 cttccagctg gggcagcttc tgtcatataa gcgcctcttt ttgctactaa cgcaactgct
    24901 tcagtgaagg atagcgcatt actagctact aatgccgaat attctcctaa actcagtcct
    24961 aaagctgcat ctgggatgat tccatgctcc ttcaataagc gataatacgc gatgctgact
    25021 gttagaatag ctggctgtgt atattgcgtc tgatccaaac gttcattttc tgtaaagcaa
    25081 agttcagcca tatcgtagcc gagaatctca cttgcttcat caaatgtctg ctttacaacg
    25141 gcttcttcat ataaatcttt tcccatacct tgatattgtg caccttggcc actaaataag
    25201 aatgctgttt tcatgttttt ctccaatata tccagaatat atgtttgatt cttcctattc
    25261 aaaaaggccg agacattcct atttcaggaa atgtcccagc ccccaaccta attttaatga
    25321 ttatgcagtt tgtttttcta cgtaagtcac taaatcttga accgttttga ttccgtcttc
    25381 tgtttcgatt ttcacgtcaa attcatcttc aatttcattg atgatttgga ataaatccaa
    25441 gctgtcagct tctaagtctt cttggatgtc agtagtcaat ttgatttctt cagtttcttt
    25501 tcctaattct tctgcgatga tttcttgaat tttttcgaat accataataa tatattcctc
    25561 cgatattgtt tgctttttat ttttataatt taacagtcta caactccatg agaatacttc
    25621 cccatgttaa acctccgcca tagcctgtaa atattacttt ctgctgtttt cccaaggtga
    25681 tctttccact agaaactgct tcatccaata agatagggat gcttgcagca gatgtattcc
    25741 catatttatc catattggtc aggaactttt cttgcggcat ctttactttt cgggcaattt
    25801 tctcaataat tctgaggttt gcctgatgca aaagcagata atcaactggt ttgtctttca
    25861 tgacttcttg gatattgttt gcaacgtctc gtacggcaaa atcaaaaata tctctgccag
    25921 tcatttgcaa ataatacgaa ccttctgaat cttctgaata gaacggattt ttattttgct
    25981 ggtagccagc ggtcaatgag ctacttctgg taccgtcagc tgctaatttt tctttcagca
    26041 attttttctg tggattcgct tctaagagaa tcccacctgc tccatcgcca aacaacacag
    26101 cagtcgtacg atcagaccaa tcgattagct tagatagtgt ttcaccacca atcactagtc
    26161 ccttagttga gccgcagcgg atcatttttt cagccatgct taacgcataa acaaatcctg
    26221 agcacgcagc actgatatca aaagcgatag catgagttgc tcccaatttc ccttgtactt
    26281 gtgctgctac agatggcgtc gtgtaatcgg gcgacattgt tgctactaaa ataaaatcca
    26341 aatctttagg gtttagattt ttctgtttta tcaatttttc cgccactaaa atgcataaat
    26401 cagaagtctc ctgatttgtt acacatcttc gttcacgaat acccgtcctt gacgaaatcc
    26461 attcatcaga ggtatccatc atcttggaaa gatcattatt agtaataatc ttttcaggaa
    26521 ggacgctggc tgttgcagta atcattccaa attgttccat taaatatcct cacttatagt
    26581 cttgcaagaa gtcgtgcaag tttttcagtg catccagcaa ggcatgctgt tcctccgtag
    26641 ccattccgtc taagatgttc ttgaccattt cacgatgaaa atgctgatgg acccgaaata
    26701 gtaactttcc ttttttcgtt agtcccaact ttacaacgcg gcggtcatct tcactgcgga
    26761 tacgttcgac atagcctttt tttactaact tgttaatagc agtggtcaag gtcccaacag
    26821 taattgatag ttctttggct acttctgaag ttgttttttt cttgtacatc ccgattgcct
    26881 cgatcgtgtg catctctgtg attgacagat ctttgaattg agattttttc agctcagact
    26941 cttcgattgt caaaatatca ttgaagacac taacaagata atcatttact gtttttaaat
    27001 ctggttccat gttccaccgt ccactaatta gtttgattat caaatctttt gatgttcaaa
    27061 ctatatctta acttttttca aaatgcaacc ttaaaagatc atttttttac tatatgagct
    27121 ttttttaaga ttttactcat ttaaaacaac tgataaatca gcatttataa tttcttttat
    27181 tagaaaaatc atctatctca catattttga ttatcaaagt attttctgtg aacagaacta
    27241 tagaattcct taaaacttgt ccattatttc aaaatttgtt atagtctttt tattcaaagc
    27301 gtaaaaggag atcctatgtt aaaagaaaaa atgaaaactc tccccatgct gccgggtgtc
    27361 tatcttatga aagaccgtga tggtaaggtc atctatgttg gtaaagcaaa acggctcaaa
    27421 aatagagtaa gcagctattt tcatcagaat aaacagcatt caaaaaaagt attacgtatg
    27481 attcatcata taacagattt tgatttcgtc gtagtagaca cggaattaga tgctttattg
    27541 ctcgagtgtc aattgatcca acattaccgt cctttttata accgacaaat gaattatttc
    27601 agtaattata attatgtaca tattaccaat aagggatttg tattaacaga tactcctacg
    27661 gctcgaacat acgggccttt tcgtctctat aaaaaaatgc cgtctatttt gcgtataatg
    27721 gaagaaactt atcaaatgcc ttggttgtct gaaattagtt tgttagcttt gcgagcccag
    27781 cttcctgacc tacaggaaat gacttttgaa cagaaaaaaa aggaactcca agggctgttt
    27841 caaggccaaa ataaaaagct actaacttac ttgaaaaaaa gacaacaaca tttcatctat
    27901 cagttgaatt tcgaaaaagc cggtatgctt caaaaagata tcgaattagt tacttatttt
    27961 attagacgga tccaggaaca aaagcatttt ttaagaacac catcgctcac cttcagcatg
    28021 ccattagcag cagatgagag tcagaaaaag cactacctcg tttgttatgg tcaacttgca
    28081 gaaacaatga ttgcctctgc tgacgtttct cctgacttct attatgaaaa gaaagaagct
    28141 catttatctt tgaaacgtca attgtcaaaa gaagaaatcg atcctgtaca aatcttgatc
    28201 agttaccgca aaaaattaga aaaagaacag tctgaaattg aactgttaaa caaaaaagaa
    28261 gctgaaaagc aactaaatta gttgcttctc ggcttctttt aggcatcttc aacttcaaat
    28321 gtcaattatc ctaaaattta ttggattaag tcatagattt ccatcgctac gatatcgata
    28381 ttatcaaatt cgtattgctg atgagtatct gtttcagtta attcaaatgt atcggtcgct
    28441 ttatcataag ttactgtaca cttctctacg ccttcttttt caaaacggcg aacttgcagt
    28501 tcattatctg ctgactcgac catagcctcc agtcgtttta tgattgcgac taattgtgaa
    28561 tgtgtcatcg gaggtcctcc ttttcttatt tctgttatat tgtatcaaaa gcatagccta
    28621 cttgcattga ttttctctaa aaaaactcgt tttttatgat tttttttctg gtatttttcc
    28681 ttcaggccac caaagtttga tcaaagcttg ggttccgtca ttctcaaaac ctttatctgc
    28741 caactcttca tatagtttca atgcttgggt agttgctggc aatacaaggt ccattttttc
    28801 tgcttcttct aatgcaatct ttaaatcttt gataaaatgt ttgacaaaaa aaccaggtgt
    28861 gtaatcttct tttaaaatac gaggagaata attgcttaaa gaccagttag ctgcacttcc
    28921 acctgaaagc gtctcaatca ctttctttaa atcaagtccg tttttttgtg catagacaag
    28981 catttccgtc attcctgtca tcgtacctgc aatcatgatc tgattagcca tttttgtatg
    29041 ctgacctttc ccagcagaac catgcaatgt aaatgtcgta ccaaattctt tgaataaagg
    29101 cagtacttga tcataaacgg cttcttctcc accgaccatg atcgtcagtg taccattctt
    29161 tgctcctaag tcaccaccgg ataccggtgc atctaacgca tctgcgcctt tttcttttgc
    29221 tgtttttgca attttttctg ccaggcttgg tgtacttgta gtcaagtcaa ctaaaatatg
    29281 tcctgagata tctgcagaaa aaatccccga ctgtccatag tagatttctt ctacatcttt
    29341 ggggtaacct accattgtaa agagaatatt actttgttct gctaccgctt ttggtgtatc
    29401 tgcccagata gctccttctg ttactaaagg atcagctttt gcttttgtcc gattatagac
    29461 agctacttcg tgtcctgctt ctagtagatg gcgtgcgaca gcacttccca tgacgcctgt
    29521 tccgataaaa ccaagtttca ttttttcgac ctcctaaaaa tcaaaaatcc ttgcttctat
    29581 gctagtatac gctagaaaca aggatttttt cataaaaaat gtttgaattt tatcttttaa
    29641 atgaatttaa ttttattttg attcgttcaa tcgagtcttc ttcttctttt cttcgcatct
    29701 cttcttcatg ataaacaacc atgtcttgat aaaattcgat catagcttcg ccgaaatgtg
    29761 tagatgaaat atcataaagt ttagcttcta aaacttttgg atctttagga acttcactgg
    29821 aaatataatc aataagtgct ggtgcaaagt cttcgtcggt ttcaaaagtt ttccctaatg
    29881 aaggatgatc aaacaatcgg ttcaaataag catttccttc cacgacacaa ggtgttccgg
    29941 ctgccatcgc ttctgtataa gtaagccctt gtgtttctga agtagaagca ctgacaaaat
    30001 aatctgccgc tttataataa agtgctacat cattgttgtc cacttctcct gtgaactgca
    30061 caaattcttc taactgcagt tctgagatca attcctctaa ctcttctaca taaggtcctt
    30121 ttcctacgat aactaatctg gcgttaggat aagcggagat gacctgagga aacccattaa
    30181 tcaaggcttg gatatttttt tcataagaaa tcctgcttaa agaaagaatc atcaaatggt
    30241 tttcctgaag acctagtgac tcccttaatt tgctgatatc ctgctgagtg atatcagaac
    30301 gtttgaattt ttcaatgtcg ataccagtag gaatcacgcg aagcggtgct attacaccat
    30361 agctacgtaa tgtatcaata acacgttcac ttggacaaac tacacctgtc gtatgatttg
    30421 caaataatct agacaagtat tttacatggg attgcctgat cacttttcct ttaccgatat
    30481 aatgaaggta gtcttcatac atcgtatggt aagtatggat cagaggtatt ttcaacttct
    30541 tagctaccat cttcccaagt atccctgctc cgaattctgt atgggtatga ataagatcta
    30601 gttctagttc tttggcaacc aaataagcat accacatgcc tctaacaaca actcttcgat
    30661 ccttgaaaga aataaatggt acacttggca ttcgaatcac atctttttcc aacttatccg
    30721 cattaggatc ggtcgttgta aaaatataga cttcatgccc atgtctttct aattcttgtt
    30781 ttaatgtttt gatcgatgta gcaactccgc tgacttgcgg aaagtaggta tcggtaaaaa
    30841 agccgatttt catgtttttc gcctccaaac tagtccttga cctgatttac tttttttaat
    30901 ttgctagaga ctttttcatt cagtacactt tcgtatacat ttttaagttc ttcaccgatt
    30961 ttattgatac ttcgctcttt tgctgtttga taaccggctt gtgtcgtact cggtagttct
    31021 tgattggtaa tctgttggat cagtcggata aattcttcgt ttgtcttccc catatagcag
    31081 ttcttgctat cttctaacca gccattatac actggaatat ctcgaacaag tacgttttgt
    31141 ttgcttgcta aagcttctaa aacaacgatc ccttctgtct cttcataaga agggaaaaag
    31201 aatagatctg cacctgaata cgcaccttct atgatctctc cacgaatgta accaggaaac
    31261 aggacatttt caggatgatc ttcttttaca attttccgga tgttccgagg aatcgagtac
    31321 atgggaacat gaccaaacca aataaatgtg tattcgggca tcttcttagc aatttctacg
    31381 aaatcaatga ttcctttacg ttcgaaaaac aaaccgacac aaatgattac tttttgatcc
    31441 ggagacagtt tgaaatattc tctgaacttt tgttctttca ttggatcagg gcgatatttc
    31501 tctaagtcga tcccattgga aatagcttga atcggcacac ggatactata gctttccaac
    31561 aactgttttg aataaggtgt tggcgtgatc agatagtccg ctttttggta caatcctacc
    31621 agatattttt ttacgatagg agaaagctgg ttcgatccga taaaggaatt tcggaaatct
    31681 tcctctgtag aatgcgcatg atagacaact ttttttcctt ctcttctggc tttattgacc
    31741 atattatgac tattgattcc gtatgtattg atgtgcagga tgtcataatc ttctttttca
    31801 tctagtgtat aagagatacc gacttccgtc agagcacgtt tttgatgatc aagcgcacgc
    31861 ccgattccag attttgcaag catcttttca ctttcaaaat ataataatac cttcacctta
    31921 cgtccccctt cacttatata gtataacata gcctacaaac tgtcactcaa acttaagccc
    31981 tatttttatc tattcttact gacaaaaacg ttttcttaaa aaagaacaaa aaaactggcg
    32041 tagctctttt acaagccaca ccagcttttg atacgttgtt tattttacat attcatgaac
    32101 aagttcaacg acttcttcca tcgtatcgca ttctttcaat gcacgatcag caagttcagc
    32161 cattttcgct gtgtccaagc gtttcattaa actacgcgtt ttaagaatag atgtcgcact
    32221 cattgagaac tcatctagac ccatacctac tagcaatgga acagctgttt gatctccagc
    32281 catttctcca cacatacctg cccattttcc ttcagcgtgt gctgcatcaa ttacattttt
    32341 gatcaaacgt aaaattgatg ggttatatgg ttggtacaag taagaaacgc gttcgttcat
    32401 acggtctgct gccattgtgt attgaatcaa atcgttcgta cctacagaga agaaatctac
    32461 ttcttttgca aacttgtctg ctaagactgc tgctgctgga atctcgatca tgatgccgac
    32521 ttggatcgta tcagatactt ccttgccttc actgatcaat ttttgttttt cttcttcaaa
    32581 gatcgctttt gctgcgcgga attctttgag tgtagctacc atagggaaca tgatacgtaa
    32641 gttaccatga acagatgcac gaagcaatgc acgcatttgt gtacggaaca tttcgtcgcc
    32701 ttgttcagat aaactgatac gcaatgcacg atatcctaag aatggattca tttcatgagg
    32761 taattgcaga tatggtagtt ctttatctcc accgatgtcc attgtacgaa caactacagg
    32821 ttttccttcc ataccttcta atacagcttt gtaagcttca tattggtcat cttctgttgg
    32881 gaagtctgga gaatccatat acaggaattc agtacggtac agaccaactg cttctccacc
    32941 attattatgg acaccaacta gatcttttgg tgttccgatg tttgcagcta attcaaaatg
    33001 cttgccgtca gctgtgacag tttctgcatt ttttaatttt tcccattctg ctttttgtgc
    33061 tgcgtaatct gcacctgctt tttcaaattc agctttttgt tcatctgtag gatcgatgat
    33121 tacatcgcct tcgatcccgt tgacagccaa aatatcgcct tctttgactt tagcagtaat
    33181 ttcttttgta ccaacgattg ctggaatttc taaagaacgt gccatgatag cagaatgtga
    33241 agtacgtcca ccaatgtctg ttacaaacgc ttttacaaaa ttgcgatcta attgtgctgt
    33301 atcacttgga gtcaagtcat gtgcaacaac gaccacttct tcgttgatca ttgatggatt
    33361 tggtaaagta acgcctaata agtgcgctaa aatacgttta gcaacatcac gaatatctgc
    33421 agcacgctct tgcatataag cattatcttc cattgcttcg aacataccga tatacatatc
    33481 cgttacttct tttagcgctg attcagcatt tacgctgttg tctttaatat tttgcttgat
    33541 ttgacctacc atttctggat ctgaaagaac catcaaatgg gcatcaaata cttgcgcttc
    33601 tgcttcacct aagctttgcg ctgctttttc acgaatttgc tgcaattctt cagtagattt
    33661 agctaatgca gcatccaaac gagcttcttc agccgcagta tcttctactg ttgccttact
    33721 gaatgttaaa tccggttgaa ctagcaggta agcttttgca acggctacac cgtcactagc
    33781 ggcaatccct tttagcattt caaccattat tcagataagc cttctttctt cattgtttca
    33841 acgattgctg ccattgcatc agcttcgtca gcaccttctg cagtaatagt aacatcagaa
    33901 ccttgaccta cacctaaaga cataacgccc atgattgatt tcaagtttac tgatttacct
    33961 ttatactcta agtttacatc agagttaaat ttgcttgctg tttgtactaa tagtgtagct
    34021 ggacgagcgt ggatcccagt ttctgctact acgtgaaatt ctttcttttc catattaatc
    34081 ggtctccttt aagtgagtgt tgtttttatg tgagggtttt cttttttagt aattcagaga
    34141 atcctaacaa atgccaccct ttcatctgta aagattaaca ttttttttcg ttagatacaa
    34201 cagttttcat tcaatttcag ataaaagtat tcaaattatt ccggattctt tttcatcctt
    34261 ttcttcacat tttataacaa aagtgtttat tttctttttc ttgtcgcttt ctcttctcct
    34321 gacgtttatc attctttcct ttgaccctct ttgttttcat atgaaacgaa ttacttgctt
    34381 ccctttttat ttttagtata ataagagtca aaggtcagga atggtcaata gagatttcac
    34441 cttttctacc tcataaatct cttaaaaaac taggggttat tcttttacct catgaaaaac
    34501 gagatgtaaa atatggatgt acccattttt gtgaaaggac gtgaatgatt catgctttgt
    34561 caaaactgcg gcaagaatga ggcaacgatt cacttgtatg ccactgtcaa tggtcagcgg
    34621 acacaactcg attactgtca gagctgttat caaaaaatca aaaatcaaca aaatggaggt
    34681 ctgactaata tggcccaaaa tgatccattt ggatttggca gtttggacga tcttttccgt
    34741 tccatgtctc gccaaatgca acagcaagga aattatgagc aaacaccacc aacacaattt
    34801 ggcggaaaca acaacttcaa tggtggtcag ccacctcaag gcaatacaga aggtttattg
    34861 ggagaatacg gaatcaatat cacagaacaa gcacgacaag gtgatatcga tcctgtgatc
    34921 ggacgcgatg acgaaatcaa acgagtcatt gaaattttaa atcgccgaac caagaacaat
    34981 cctgtcttga ttggagaacc aggtgttggt aaaacagcag ttgttgaagg tttagcacaa
    35041 aaaatcgtag atggtgatgt accgcaaaaa ttaatggaca aagaagtcat tcgtttagat
    35101 gtcgtatctt tagtccaagg tactggtata cgaggacaat ttgaagaacg tatgcaaaaa
    35161 ttgattgaag agatccgtca agcagaaaat gtgatcctat tcatagatga agttcacgaa
    35221 atcgtcggtg ctggttctgc tggtgatgga aatatggatg ctggtaatat tttaaaacca
    35281 gctttagctc gaggagaatt gcaaatggtt ggtgctacta ccttaaatga gtaccgcatc
    35341 atcgaaaaag acgctgcttt agaacgtcgt atgcaacctg tacgggtaga tgaaccaact
    35401 gtcgaagaaa cgatcagtat tttgaaaggt ttgcaaaaac gttatgaaga ctatcatcat
    35461 gtaaaatata ctgatgaggc catcgaagca gccgcaactt tatccaatcg ttacgtccaa
    35521 gatcgcttct tgccggataa agccatcgat ttgctagatg aaacaggttc taagaaaaac
    35581 ttgacgatcc aaatcgttga tcctaaaaca atcgagaaaa aactgcaaga agcagaagaa
    35641 caaaaagttt tagcttctcg agaagaagat ttcgaaaaag cagcttatta tcgcgatcag
    35701 atcaataaac ttcaaaaaat gaaagaacgt cagctcactg aagaggaaac acctgtgatt
    35761 accgaaaaag atatggaaaa aatcgttgaa caacggacag gtattccagt gggtgaatta
    35821 aaagaaaaag aacagacaca actgaaaaac ttagcagatg acttgaaagc tcatgtcatc
    35881 ggacaagata acgctgtaga tcgagtagcg aaagcgattc gtcgaaaccg tgttggatta
    35941 aacaaacaga atcgtccaat cggctccttc ttatttgttg gaccaactgg tgtaggtaaa
    36001 acagagcttg cgaaacaact tgcctacgaa ctattcggtt cacaagattc aatgattcgt
    36061 ttcgatatgt ctgaatatat ggaaaaacat agtgtctcta aattgattgg ttctcctcca
    36121 ggttatgtcg gatacgaaga agctggtcaa ttaacagaaa aagtacggag aaatccttac
    36181 agtcttgtct tgttagatga agtagaaaaa gctcatccag atgttttgca tatgttcttg
    36241 caaatcttag atgatggtcg attgacagat gcacaaggaa gaacggtcag ctttaaagat
    36301 acgatcatca ttatgacaag taatgccgga actggtaaag tagaagcaaa cgttggtttt
    36361 ggtgcggcac gcgaaggtgt tactcgttct gtattgaacc aattaaacaa ctactttaca
    36421 ccagaatttc tgaaccgttt tgacgggatc atcgaattca gtgcattatc aaaagaaaac
    36481 ttgatgacaa tcgtcacact aatgctagac gatgtcaacc aaatgctggc agcacagcaa
    36541 cttcacatcg aagttcctac gaatgtcaaa gaaaaattag ttgacttagg ctatgatcca
    36601 tctatgggtg ctcgtcctct tcgacgcacg atccaagaac aaatcgaaga tggtatcgct
    36661 gaattttatc ttgatcaccc ttctatccat gagttgaaag caaaactgga taaagatgga
    36721 aaaatcatcg ttacttctaa accagaacgt ttggctaaag aatcagccga agaaacggct
    36781 gaataaatcc agttttatag cgtgagacgg tatttctttg agaaatgccg tctcattctt
    36841 ttttcagaaa agtcaaaata ctgttcattt tataaaaaag aaattataat aagagaaaca
    36901 agcaattaaa aatacataaa agaggtgagc gccatgaaat tggtaaatgt aacaaacagc
    36961 cattcccgtc ttgtattaaa ccagcttgaa aacactgatg cccatctagt caaggtctac
    37021 acagccggaa ataccactat tgtctacact gaagcccctg aacataatga aattctgctg
    37081 atcaatgaca aacgtaaaat ccagccgaaa gaaatcgaag atgctaaaaa ttatttctta
    37141 gataaaatca aagacgccgt ttaccacgag gatgaaatca aagtaatcga attggcaggc
    37201 cttgttgaaa tctcgattcc aaaacatgaa ttaggcgcta cattagccgt gtaaacaaat
    37261 tttgaacata ataattaaag agcgtgggac aaaagtaaag aacacttttg tctcacgctc
    37321 taaacacgta taaacggcgg aagcagaagc aactccttcg gaaataagct aaaattcacg
    37381 aaaattgctt ttcaaatttt tgtgaattcc agcttatttc ttggagttaa acgcttctgt
    37441 ctcagcctct ttttctttct agctttttga tttttctctt ttcttttgta cttttctctt
    37501 ttcattttca gttctacgcg tgtctttatt tttaactttt tcctctttat ggatgattga
    37561 tcgtactttt tgtgcaattt gctcgttttt gtcccagtct tttacatcta ataatcgaca
    37621 taatcgtaac atctcttctt ttttctgttt ttttctttca cgtatttgcc attctgtttc
    37681 catgtgtcac actctccttt ctttaatcat atgtacgcaa aataattttt atattttttt
    37741 gattagacat ttctatgatt ttaatatagt aaaaagagcc gtcacggaaa atccgtcacg
    37801 gctctaaaca aaatatgaga ggctgttttt gtttggctat tcttattact tgatgcaggg
    37861 cagcttgtgt caagacttct ttacatcaaa ctttttaatt ttacattagg atatttatcc
    37921 gcaaaccagc gttctgcaaa ttggttctcg aataagaaca atggttggtc gaaacggtca
    37981 cgagccaaga tattgcgact tgaactcatc ttctcatcca aatcttctgg atcgatccag
    38041 cgagcgattt tgtgtcccat tggagacatg attacttcgg cgttatactc atttaacata
    38101 cgatattgga atacttcgaa ttgtagctga ccaacagctc caatgatata ttcttccgtt
    38161 agatatgttt tataaagctg aatcgctcct tcttgaacta attgatagat tcctttgtgg
    38221 aaggattttt gtttcatgac attttttgca gtcactttca taaacagctc tggagtaaat
    38281 gaagggagtt cttcataagc aacttttagt tttccttcga acaatgtatc cccaatctga
    38341 taattgcctg tatcatatac accgatgata tcgcctgcta ctgctttttc gacgttttct
    38401 ctcgaatctg ccataaattg tgtgacattg cttaatttca gttttttatt tgtacgttcc
    38461 aaccagacat ccattcctcg ttcgaatgtt ccagaacaga ttcggacaaa agcgattcgg
    38521 tcacgatggg ctggattcat atttgcttgg atcttgaata cgaaacctga aaattcttcc
    38581 tcataaggac ttaccatctg atcatcttgt gttttgtgtc cataaggagc tggtgccaat
    38641 tcaacgaaag tctctaaaaa agtctgtaca ccgaagttag tcaatgcaga accaaaaaat
    38701 actggtgtct gatcgccacg agcaattttt tcttgattaa atgcatctcc agcctctttg
    38761 attagttcta cttcttctaa gacttgttca tataaggaat tttcagttag aggatgattt
    38821 tcgggaagca gtccatcttc atccaattct actaatcgtt catcctgata attttccgga
    38881 cgataaaact ctacacgatt atggtagata tcataaagac cttctagccc tttacccata
    38941 ccgattggcc aattcatcgg ataagattcg atatctaata gctcttctaa ttcttctaac
    39001 aattccaatg gttcacgacc atcacgatct agtttgttga taaaagtaaa tatcgggatg
    39061 ccacgttttt ttacaacttg gaataatttc tttgtctgtg cttcgatccc ttttgcacta
    39121 tcgattacca tgaccgcact atccacggcc atcaaagtac gataagtatc ttcagaaaaa
    39181 tcttcatgtc ctggtgtatc caagatattt actcgtttcc cttgataatc aaactgcata
    39241 acagaactag taacagaaat cccacgttgt ttctcgattt ccatccagtc tgatttggca
    39301 aaattacctg tttttttgcc ttttacggtc ccggcttgac ggatagcccc accaaacaat
    39361 agtaattgtt ctgtaatcgt tgttttccca gcatccggat gggaaatgat cgcaaaagtt
    39421 ctgcgattgt ccacttgttg ctttaattct ggattattca taacctaact ccatttcttc
    39481 cattcaatta tttatatttt ctctaggcac agattgtccg atctcttaaa gaaagacaat
    39541 ttcatatagg gctgtgacaa aagccgtgta gcagtctctt tttccgagta aacggcgttc
    39601 tagagacagc ctatcagcaa taagcccacc caagccaaaa atacgaaaag ctgtttttgc
    39661 ttggctgctc ttattactta atgcaggata gctttttcac aacctttgtc aactactaca
    39721 actgaatcag tatagcatgg attcatcgaa tgaaaaagcc accaaaccat aagagtcaaa
    39781 tatttttttg tcagctgact aaaagaaaag acgtgttgct tgtttattca agcaacacgt
    39841 ctttcataac caagtttcca attatcttct tggctcgtca tcttcgaatt cttttctgaa
    39901 gtatcttcgt tcttcttcag gttccgcttc tgtttcttcc ggatcatgaa aaatgacacg
    39961 gattttaagg attcgagaac cttccatttc ttcagaaacc agcgtaatat tatcgacatc
    40021 aaacgataac ttttcgcctt catccggaat catgcctaat gctgtaatca aataaccagc
    40081 catcgtatct acatcactca tatgcagatc actgtcaaaa gcttcattga actcatcaat
    40141 cagcatacgt ccttggatga tatattcgtg ttcatcgatt ttttcataaa gattctcaac
    40201 ttcatctgat tcatcatcga tttctccgac gatttcttct aaaaggtctt ctagtgttgc
    40261 taacccaacg acgccgccat attcatctaa taaaatagcc atctgattct gcgtcttttt
    40321 catttcatat aacagatcat caataaagac cgtttcagga acgaataaag gctcctgcat
    40381 gattttcttg atatctaaat tatcaaaacc gaatttatgg gcagctttta gtaaattctt
    40441 tgtatgaagg attccgacta ctttatcttt gtcttcgtta taaacaggga ttcttgaata
    40501 gttttcggat aaaacttcat tcacattttc ttccacagtg tcgttgatat caatcataaa
    40561 tgcatccgtt cgtgggacca tgacttctcg ggcaactttc gtatcaagag aaaaaacccc
    40621 ttggagcatt tctaattctt cattattcaa tacgccttcg ttttcaagca tataacgcat
    40681 ttcatctctg gtcatttttg aatcttcatc atcaaaagtc atcggcgtga tacgcgccaa
    40741 taaacttgtg gaagcagaaa gcagccagac gaagggctta gctactacac caatcaagcg
    40801 tatcagccct gaagtgaact ttgcgacttc ttctgattta tttaaagcaa tacgtttagg
    40861 gtacaattct ccaaaaacaa tcgatacata ggtcaaaata gccagcacaa tgatatttgc
    40921 aatatttttt gccgctgtgc cgccacctaa taccggagct aaccgttccg ataaagtatt
    40981 agctagtgaa gcaccagaca aaatgttgac caaagtgatt cctacttgga ttgtcgatag
    41041 gaaattattt ggattctgca atatttttaa aagcttttga gatttcacat ctccttcatc
    41101 agctttttgc tcgattcgat tcttattgat cgaaacaaca gcaatttcgg aagctgctaa
    41161 aaaagcattg atcaatgtca aaacgatcaa taataaaatc tgcgctaaca gcgactgact
    41221 ctcagggtca gcattcataa tcgcattctc tccttataaa attaattttt agtttacgat
    41281 agaaaaaaac gtggcactat agccacgtta aaatggtatc acaaagcaat tttctttgca
    41341 ataaaaacaa gtgtactaaa actacctacg aggtcgtagc aattttcttc ttgttttcat
    41401 tttgcttgtc ttctttgacg attttgatta tataggaaat gatcgtcttg cagattgcgt
    41461 aaaaaggaac acctaagaag ataccaagca atccggcaat atttccagct actagaagaa
    41521 cgataatgat cgttaatgga tggattttca gtgatttccc aattacatta ggataaatga
    41581 tattcccatc caactgttgg acgattagca caaccacaca acaaagtaat gcttttaccg
    41641 gatcattgaa gactgttact agaaatgcag gtgctagtcc tagataaggt cctaaatatg
    41701 gaattaggtt tgtcaatccc gcaatgaccc caaataagaa agcataatcc acaccaatta
    41761 ccatatatcc taaaaatgtg aaggtaccaa cgaataaaca ttcgattgct tgtccgctaa
    41821 tgtaattagc caatgtttta ttcagttgcc ccaataactc cacaatttgg tttcttcttt
    41881 tttctgggaa aaactgttgg atgtttggca ctagtttttc tccgtctttc aacatataga
    41941 acaagatgaa tggtgctgta atgattacta cggttgccga agcgatcgtt ccaacgatcg
    42001 aacctaaact attggatact ccactaagga attgctgaat gattgtcccg taagaaatgt
    42061 ctaattgctc aaaatattta ttgatatcta cttccttgaa caaaggcaat tcggctacct
    42121 cttttaacca gctttctacc tgtttgatga aatcaggcat attagatgcc aatgaggaaa
    42181 tttgctgtac tagacttggg atgacactaa gtaaaatcca aataattgct gcaactaaaa
    42241 ggagcagcac aattgcgaca gcccatattc ttttgatttt tgctttcatc aacagcttga
    42301 caataggatt caataaatag taaagaaagc ctgcaatcag tacaggtgca aataacgtgg
    42361 aaaaaaatgt cccgatcggt tcgaaaataa agtttatttc tgatgaaatc atgatcaatg
    42421 cagctatgat caataattca agcgaccaaa acattagttt agactgtcta agtttttcaa
    42481 acaatagatt tcctcctttc tttcttacta gtatatatta tattcgttaa aaattctttt
    42541 attctttttt tatttttgaa aacttgccat actttttatt tgttttattt tccagtatac
    42601 tatacgaaag gaaggtggct agaccatgaa agttgtacaa acaaaagata caatgagcaa
    42661 tatttactta gatgctgtac ggatcaggca tcaagttttt gtagtcgaac agggtatgcc
    42721 tttgtctcga gaaatagaca aagatgaagc ccattgtatc cacttcgtcc tgtactcaga
    42781 taaaaaagaa ccgcaaggaa ctgtacgtct tttgccttta gaaaacggaa aaatgaaatt
    42841 acagcggatg gcgatccttt tgaagatgct ggcatgcctc atatttatat gaaaaagact
    42901 ttataaaaat ttatttcgaa aaaagcaaaa aacagcaagc ttttgagaaa aatctctcac
    42961 tggcttactg ttcttttttg tgtttactta cgcgacaatt gcttgtaacg gttataccaa
    43021 atatcaatat agccttccga gaacgggcca tctccattat tgatccagtc aaccagaatc
    43081 ttcacatttt cttttaggat gaagtcaata tcgttcggat aattcatcat tttgctgtgc
    43141 atctcatatt catcgacatc caatagtcgt ttctcgccgt caggaaatac cttgatatcc
    43201 aagtcatagt cgatatattt caaggcctca tcgtccagca aaaaaggtga agctagatta
    43261 caataatagg aaaccccctt ttctctgatc attgctatta cattgaacca gtatttttta
    43321 tgaaaataaa caatcgctgg ttcgcgcgtt acccatcggc gtccatcaga ttcagtgact
    43381 aatgtgtgat cattcacgcc gatcatagag tgttcgcttg tttttaatac catggtatct
    43441 cgccacgttc gatgcaattt gccgtcgtgc ttgtaacttt ggatcgtcac aaactctcct
    43501 tcttttggaa ctcccatagc aacccttcct taagcagcat tttgtgcttt gtgtttgggt
    43561 gttcattaca ccgacatcat aattattata tcaataaaaa tgagctttgc ctagaaagga
    43621 ttcctattgt ttcgattttt ctctaactga tctaccagtt tcatttggac cttaggaaaa
    43681 acgaccgaat caaatgcatc aggcttcaac cacttcgaag ttttgttctc ggtaaattct
    43741 tgttctgctc cctcggttgc ccgtccgtaa aaaaggagaa catgccattt cagatgacta
    43801 aaaatatgag taacttctcc taaatgtcgt gtctgccaaa caaagagttc ctgcttttca
    43861 aatgggagat tttgctcttc ttctgctact aggtcatcaa acagatcgat ttctggcttt
    43921 gtttcccatt cttttttcaa tcgctcatac tcctcttgtg tcacttccat cattggaaat
    43981 gtccacatat tcgccagcaa tttttggcta tctctttctt caaaataata cgctccagaa
    44041 tgattttgaa gagccgcact gatataataa acgtcttttg gctttgcttt ttttgttttt
    44101 acaggaaaac tcgtttggat tcctcgtttg ttagctaaac aaaaggcttg gatcggacaa
    44161 gtctcacact ttggagaagt tggtgtacag atagctgaac ctagatccat cattgcttgg
    44221 ttgaattcac ctggatgctt ttcatcaatg attttccgca tcgcttcatc aaagattttc
    44281 ctgctagaag cttttgcgat gtctgcttca atgcaaaaca atctgctgac tactcgcatc
    44341 acgttgccgt caaccgcggg ttctggaagt ccaaatgcga tacttgcaat cgcgcctgtc
    44401 gtatatggtc ctattccctt caatgagcta atttcttcag gcgtttgcgg catttcccca
    44461 tcaaattctg acatgatctg tttagcagca gcttggatgt tccgggctct tgagtaataa
    44521 ccaaggccct cccatgcttt taaaagcttt tcttctggag catttgctag ctcttcaatt
    44581 gtaggaaacc attccatgaa acgataaaaa taatcgatca ctgtgtctac tctggtttgc
    44641 tgaagcatga tctcagagat ccagatacga taaggatcac gattatagcg ccaaggcagg
    44701 tttctttttt cttgttcata ccattgaatg aactgatctt gaaattcttt tgtttcttta
    44761 tctgtccatt tttcccattc tttattcact ttcctcttcc ttttccgtaa tgaatcgctg
    44821 gatcatatcc aaatcaaatc ctttttgata taagctttgc tttactttta gatttctttt
    44881 tttaggttca aaccttaaat ttcttcgcca tagtttatct ccttgtttga ctaaataatc
    44941 atattctatt tcttgatctg cttcttgcgg aagatcagcc atcgcttgtt ggatcacttc
    45001 ttgagaaaaa cctttcgtca tcaatgtttg ttggattttt ctcaataatt ctttttggct
    45061 ttttccgcga ttttttccaa acgctttttc ggctgtctga tgtgcatttt gaacttggtc
    45121 ttcaaatgta tattggctga gcgcttgttc aatgatttca ggtttcaaac ctttttgctg
    45181 catctgctgc gctaatttct ttggtccttt gtcacttaag cgcatattcg tgcgcacata
    45241 actttcccca tagaccaaat catcgacaag gtccaattct tttaagcggg ctacgatttt
    45301 atttcgatct tcttgaagga tttccttttc ttttaagtat gttcggattt ctttttccga
    45361 tcgcaactga taacttaagt aattcattgc taggtgaaaa ccgaaatcag ctccgctact
    45421 cttcttgatc tcttggatag tttcttcgtc taattcccgt ccttttaata atcgatagcg
    45481 tactaataca tcttcagata cttgtaaagc ttctccttca gataaatcta cgcgatagaa
    45541 agggcctttg cctttactga ttctcgtaac ggttaacata aacatcctcc tcgaacatat
    45601 attctctatc ataccacaga aaatccccgt aatcaggtat tatatgttag aataaaccac
    45661 agaaaaaaga aaaagggaga tacttatggc agaaacaatt gtcaaaactg gacaaacggt
    45721 tcctttgaaa atcaagcgtt taggcataaa tggtgaagga atcggttatt tcaaacggtt
    45781 gatcatattt gttccatatg cactaccaaa agaagaagta ctagtgaaaa tcacgaaagc
    45841 aactcctcgc tatgcagaag gagaattaat aaaagtcaaa aaaacaagca aagatcgcgt
    45901 agtggcacca tgtcctgttt actatgaatg cggtggctgt caattacaac acttagctta
    45961 tcaagctcaa ttggatttta aaaaggatct gcttttgcaa gcattggaaa aattcaaacc
    46021 agcaggcttt cgatcttatc aacttttgcc gacgatcggg atggatgagc cttggcatta
    46081 tagaaacaaa gcacaatttc agttacgaaa aaataagcag actcaaaaaa ttgaagctgg
    46141 tttatacgaa gcaaactctc atcagttagt ccctataaca gactgcttgg ttcaagaacc
    46201 tcgaacacaa aaagtaatga atactgttgt tcaactattg aataaatttg atgcacccat
    46261 ctatgatgaa cggacaaaca gtggaatctt ccgcacaatc atggttagaa tcggtgttaa
    46321 aactggggag ttacaagttg tttttattac tcgcagtaaa aaattcccgc aaaaaaacgc
    46381 aatgatctgt gagatcaatg aacgactgcc cgaagttgtt tcaatcatgc aaaatgtcca
    46441 ggcacaaaaa acgtctctcg tgatggggga tgaaacgatc cacttatggg gaaaagaagc
    46501 cattgaagaa caaatcaatg aagtgacttt cgatctttct cctcgtgcct tctttcaact
    46561 caatcctcag cagaccgaat tgctttatgg cgaaggaatc aaagcattag atgtccagcc
    46621 taatgaaacg atcgtggatg cttattgcgg agttgggacg atcggcttaa gtgtagcaaa
    46681 acaagccaaa gaagtacggg gaatggatac cgttcctcaa gcaatcgctg atgcaaaaaa
    46741 aaatgcggaa agattaggat atcacaacac tcgatatgaa gtcgggacag cagagcaagt
    46801 tctgcctaaa tggttgaatg aaggttttca gcctgatggt atcatcgtag atccaccacg
    46861 tacgggtttg gataacgcat tgatccaatc attattgaaa taccctccaa aaaaacttgt
    46921 ttatatctcc tgtaatgttt ctacacttgc cagagatctg gttaatttaa gtaaaaagtt
    46981 caagattgaa tatttacagt ctgtcgacat gtttcctcag actgcacgtt gtgaagttgt
    47041 cgtgaagatg acgagactcg ctgactaaat gaaagaggtt gtgaaaaagt ctgccctgta
    47101 tcaagtaata agaacagcca aacaaaaata gctcttcatg ttttatgaat accgtacttg
    47161 tgaccgaaga gttaacagga ggacactatt tatttaaaaa aagggttgtg acatagtttt
    47221 tgtcacagcc ctttttgatt attattggat attcacgtct atcacttgat aaaatgcatt
    47281 tgtcgtatcg ctgatattcc atactgctaa aatcacatta tatccttttc gatcctgcgg
    47341 aagtgtgatc gtttggttga ctgtttttgg tggaacagtt gctttgtcgt ctatttttgt
    47401 gatcaattca aaatcactaa atttcaaagg ttgattagga ttccaagttg gtttggtaat
    47461 gtagtaatcc caagtacttg tccgatgttg tgctgttaaa ttccaagtaa tatttaatgt
    47521 tcctggatta accatgtttt tatgccatct gttagatgtc tgttcatcta aaggctcaaa
    47581 gccgctgact cctgcactag caatttttcc atcaatgaat gtatttttgg tagcttcgat
    47641 actttgcggt tcccattgtg ctcttccgac attttgattt aagtttcctg ctgctgatgt
    47701 tcctaggtat gcacggcttc ctggagaagt aatataacca tgcgcaaaac ctggaatgct
    47761 aaaaccgaac aaccctaaac taactaaccc aataaacaat aacgtactaa tctttttcat
    47821 gtagaaacct ccttcatttg ataaccacat tgtaaacgct ttattgtatt aacacaaaca
    47881 ttatgctttt ataattttat gttgaagtaa aaaaggtgaa aaaagtaaga tgcagattat
    47941 aacagaagta gacgagaaaa gtacaaatag aaaacatgag aaccaaatca tatgatcttt
    48001 ttcaaaaaca tcattcatat aaacaaatgt tcaacttttt aataacaaca atcatcaatt
    48061 tttttcttac ttcacaaact aaatacaggt cttgctgtga gccttcatgg taaactacta
    48121 ttatagaaag gagttagtaa aatgaagatg ataaaagata ttcgtttttg ggtttgtgtt
    48181 ataggaattg tcatattagg ctttttatca gggttgctta gcggaaatcc cggagaatat
    48241 tactattctt tgcaacttcc accatttgca ccacctagct ggatatttgg gccgatgtgg
    48301 accttactgt atatattgat gggtatttct ctttatttgt tacttaatca caacaacaaa
    48361 aaacagcgaa acaatcttgt cggtcttttt gtgattcagt tcatttttaa ttttatatgg
    48421 tctgctctat tttttaattt aagaaatatt ttcattgcag caatcgatat tacactttta
    48481 gttattttct tgtcagtgct tatgtatcag ttgtggctac atcatcgcct ggcaatgtgg
    48541 ctcatgattc cttattattt atgggtacta ttcgcaactc tattgaatta ttcaatttat
    48601 tttttaaact aagcgctaaa aagagacgtc ctgtaattta acacatagaa aaagtgccac
    48661 ctaagttaga ttttttgtct aatttaggtg gcactcttta ttaaccaaac tatttttttc
    48721 tagtacccac ttgttgttcc atactcatta ttctggtcat aaccataacc attttgttcc
    48781 tgtccagcgt aaggatcata actttgagta tcttgacttg gtgtatagta ctgacttgta
    48841 tcttctgttt gctgataata ggtattcgga tcttggtact gatcatatgt gttttctgaa
    48901 taggaagaat aatcggtgta cccttcacta ttcgatccat caccgtttgt cgaatcgcca
    48961 tcttccgaat catcaaagaa catcattgaa gcattctcat ttttcaaatt aggtaatgta
    49021 tcgcttgttt ttatatttaa ttgtttcttc agttcatttt ggatcgaaag aagatcattt
    49081 tttcctaaaa tttgatagta gatatcattg atcatttgtc cttcgccttg caactggtct
    49141 tgtttgattg tttcaaacgc aggggtgtag ttcgtcgcta catcaagcat gtcatcccaa
    49201 tctaagtccg tcgtcacatt gttctcaact gcttttaaaa tttttctata attgcttacg
    49261 ccatctaaac ttaaaacttt attgacgatt ttcgtcacta cttcccgctg acgacgttgt
    49321 cgaccgatat cgccttctgg atcttcgtgt cgcattcgag aataggctaa acctttttct
    49381 ccattcaatg tttgttcacc tactggtaca tggacaccat ccaaagtaaa gtcaatttta
    49441 ttattcactt tgatgccacc gaccgcattg atcaaatctt ccatgccatc caaattgatc
    49501 gttacataat gatcaatagg aatatcgagc agttgctcaa ttgaatccat ggccatttcg
    49561 acaccaccaa atgcataggc atgatttaat ttatctaccg ttccataacc tacgatattc
    49621 gtataaatat ctcggtccaa actgatgatc gttgattttt tttgtttcgg attaactgtt
    49681 actaccatca tcgtatcaga acgtccttgt tccgttcttc ctaatccacc ggtatctaaa
    49741 cctaatagca aaaccgaaaa aggttctttg tcatcaatgc ttactctctc agaacgtttg
    49801 gaggatattc gattagagtt tttagaaatt ttgtttactg tttggctcgc ttctcccata
    49861 aatctgattc cgtatgctga taatccggca atcagcaaaa caaatacccc taacaaggtt
    49921 aatagaactt tttgccatcg cttcataata cacctctgtt tcacattttc taaaatattg
    49981 tctcatataa ctgttcaatc agcaaattca ctttttaatc ataagaaaac tttaaaaaac
    50041 atttttgtgt aacgattact attttttaaa atttctcaaa attcttaact atcataccat
    50101 accgtgaaaa agatcgaaag accgaataca cgcagttcgc aatcgtttta tcttttttta
    50161 cgtatttttt ccagaaaaag cgaacaacaa ggtattttcc aaataatcgt gcagtaaaat
    50221 gatcgcacat acctttccca tctttttaac agtctttgcc taccgttcag attatcattc
    50281 gatttcacga aaatttcttc ctatgactgg tccttttgtt aaacccatct tctattcgtt
    50341 ttatttccag ctcactgcat ggctcttaaa atgactcgaa ctagtgattt cattaccatc
    50401 atcttttaat ggatagatat gctcctcttc aaagtaaaac gattttcttt taaagtaata
    50461 gaattgacat ggtaatgagt atgtatacta gtggtttcac aaatggtctt ttattcaaca
    50521 tccaaaaact gaaatttctt taaaatccat tactaacgaa gaaaatgttc cttgcttgat
    50581 aattagttag gacatgtcaa gtgaacaaat gcatttactt agccaaaaaa tctaaaaact
    50641 tcataaatag acaaaaagac acgactctct aagaagtcgt gtctttattc aacaaattat
    50701 tataatttag tcacttcagc agcttgaggt ccgcgtgcac cttcaacaat cgtgaattct
    50761 acttcttgac cttcttctag gctcttgaag ccgtctcctt gaattgctga gaaatgaaca
    50821 aatacgtcat ctccgccgtc tactgtaata aacccaaatc ctttttcatt gttgaaccat
    50881 ttaaccgttc cgtgttccat aaatgtatag cctccaaaaa agttcttgca agtaaccttg
    50941 caagaacatt atacccaatt tagaaaacgc tagcaagctt tcgctctttt attttccaaa
    51001 ttatttttaa gactgatatg acggaggaaa tggttatttt gctgcttcga aacgtttgtt
    51061 tacttcatcc caattaataa cattccagaa tgctgcaata taatctggtc ggacattttt
    51121 atatttcaaa taataagcat gttcccaaac gtccaaacct agaattggtg tctttccttc
    51181 catcaatgga gaatcttgat ttgcagtaga ggtaatagct aattttccat tttccattac
    51241 aagccaagcc catccagaac caaatcgtcc agcggctgct tttttgaatt cttctttaaa
    51301 agaagaaaaa tcaccaaaag cttcattaat cgcttctttt atttctcctg taggttcgcc
    51361 accagcattt ggtgccatga tttcccagaa aaatgaatgg ttagcatgtc cgccaccatt
    51421 gttacgtaca gctgtcttga tatctgttgg aatagcgtcc atatcagata ataattcttc
    51481 tattgttttt tcgcctaatt ctgggtattt ctcaattgct gcatttaaat tcgtcacata
    51541 agtattgtga tgcttatcat gatgcagatg catcgtttct tcgtcaatat aaggttccaa
    51601 tgcgtcatat gcataaggta gatctggtaa tgtgtaagtc ataaaaaaat tcctcctcaa
    51661 tgttttcttt ataatgtcta cattacaaag agtaacaaag agaaggaaat tcttcaattg
    51721 ttatgcctag tcgtcttttt cactttgacc tacttcttct tcaaaaacct cagtttcttt
    51781 aaaaataaac aacttgctga aaatatagtt cgctaggata acaataattt gagtgatgat
    51841 tttcgccaca tactcattgc tgttcataac attgatcaac aataccattg cccccatgtc
    51901 caatccgtaa gaaaggatac ggtagaagaa gaacttaccg cattcaataa gtgcatgtgt
    51961 aaaattcggt gattttgaat ggaataccca aagtttgttc gttacaaaag caaacaatac
    52021 agaacaaaac cacgaaatag aattggataa ggccatactt aaatcaaaat attggcgtgc
    52081 gagagcaaaa ctaacaaaat ttacaatcgt agccaaacca ccaaaaaaga gatagactag
    52141 tatctcccaa tatccttttg cttctaaata tccttttaac tgtcgatact gcttcatgag
    52201 ccaacctacc ttattaaaaa ttcttattta tcatactcta tatttcaata actttcatct
    52261 ttatttaaaa aaattaattt tttttgatcc tttgcctttg tctctgcttg gatcgtcaca
    52321 tgtgtaatac catattttaa ttttaataaa gaaattatac gaggatatat cttttcaatc
    52381 tcgcttagta gctgatcttc aaaatcaata tgtccgtcga aaataattat cttttcgcta
    52441 tactgccaaa tatggacatg atgaacattc tttaccccat cgattgcttc aatttcttgt
    52501 tccatttttt catagtcaat agcaggtgca ctttgtatca aaatagcggc agcttttttg
    52561 atcaccatta tcgcttctat caatatatat atcgaaatga tcagtgtaat aactggatcg
    52621 atccagtaga tatcgaaaaa acggatcaaa attgctccga taatcacact taccgaagac
    52681 agtgtatcac ttaacaaatg caaataacta gattttatat tcaaactttc atctgcttct
    52741 tgtcgtaata ataatactga gaacaaattc gcgagcaatc caataactgc tactgttagc
    52801 atcaaatgac tatttatctt ttctggtgaa gtgaaccgct tgaatgcttc aacggttaaa
    52861 aacaaggata atatgatcaa tatgaatgag ttgatgaaag cactcaatat ttctaaacgc
    52921 tggtagccat acgtacgttt tttatttgct tcttttcggg ccattttttg tgccccgtaa
    52981 gaaaaaataa ttgccaatgt atcactaagg ttatggaaag catctgaaac aagagacaaa
    53041 ctccctgaca taatccctcc aataaattct gataaagtga tcaccgcatt caaaaccact
    53101 actccaaata gtttttttga tgatctctgt ggctgtgtag gcactattcc ttcctccatt
    53161 ttatttatat tggatagtct ttagacaaga ataacatttt tttgatattt caccaatcat
    53221 tcagatgttt ccctaaagca cttgtatttc acttgatact tcgctagaat tgcaagtgat
    53281 gacactacta gatgaggagt acttatgaca acaaaacaat taattatcag ttcctttata
    53341 cgattcaaag acctaaagga ggcgagaaat gtcccatttt ggaaagccat tgtctatctt
    53401 ttagttttga gtataattat ggctttgcca atctcttttc aagtttttca agtcttaaat
    53461 aacattcaat tggatgggca aaagattgct actcgcattc ctgattttac aatccaaaac
    53521 gggcagcttc aaaccgaaga aaaagaagga ttcatttacc aaacaaactc cattatcttc
    53581 acatttgatc cagagggaaa acgaacagaa caggacatct ctactgattt gatggggaat
    53641 tttgttagtg tcgggatgtt aaaaaacaaa cttatcatag ctcttcctaa tacaggcacg
    53701 acttctgctt tgttgaacaa taaccaatta gaacttccct acaccaatga atctttaaaa
    53761 aacttaacag gtaagcagct ccgttctttt ttaagtgaag catctatacc actttggata
    53821 aaagtcctga catttatatt ttctatttat cctagttttc tgaatctgct gatcactttg
    53881 ctatttacca acattgctgc ttttctctat gcacgctttc gactaacaaa agctactttt
    53941 cttgattgtt taaaaacatt gatctattca atttcattgc ctactataat tgcaacaatc
    54001 ttgatggtct ttcttccttc ttttgacact agcgccttca ttgcttttgc aggaatcttt
    54061 atttttgctc aagctgtcaa aggatgggca aaaatatcga tcaattaaga aataaagaca
    54121 actcgttatt tctacttaaa tagacccttt tagaggttgt gacatttttt tgtcacagcc
    54181 ccttttttat ttgaaaaata tttctttctc aaaaaacaag caaggcgctt caaagttctt
    54241 cttgtatgcg ctacacttag agtaaagaaa ggcgggaaat taactatgtc agaaagaatc
    54301 atttatgcag atcgtccatt tcgtgatgaa tttatcgaag aaatccatac tatagcgcct
    54361 ggttatatct ttaaaacaga attacaacca gaggatctac aaaatgtaga gatcagtttg
    54421 ggctggaact cagactacca agaaaaacta ttagcctctt ctaccttgaa atgggtccaa
    54481 tctatctcag ctggtgttga tcagctaccc cttgagactt tttcaaagaa acatatttta
    54541 ctttcaaatg gtagtggcat ccacagtgaa tcgattacgg agcatgtctt aggaatcatc
    54601 cttgggtatt ctcgtggtct ttttcaagca caaaaggcac agagtgacat gaaatggtta
    54661 ggttcatcgg tccattacca atctatccaa gggaaaaaaa tactaatcat tggaactggc
    54721 catattggaa aaatgattgc aaaaaaatgc aaagcattag acatgaactg ctatggaatc
    54781 aatacatccg gtcatccagc agaaggaatg gaaaagactt tttctttaaa tcaactaaag
    54841 gaagttcttc ctgaagtaga tttcgtagtc aatatcttac ctctaacgga ggaaacaact
    54901 gggctctttg atcagcatat gtttgaacac tttgatccaa aatctgtatt catcaatgtt
    54961 ggccgtggtg cttctgttaa gacacaagat ctggtgcagg ctttaaataa ccagcaactt
    55021 tcctttgcag cattagacgt ttttgaggaa gagcctcttc cacaagatca tcctctttgg
    55081 aaaatggaca atgtactgat tacttcccac attgcaggtt tgacacctga ttttcaaaag
    55141 aaattaatgg ctattttttt aaccaatctg aaaagctact ttgccaccca tgagcttcaa
    55201 accaatcaag taaaattgtc tgcaggatat taatagctga aaacaatatt ttcaaaagaa
    55261 aaaagagaag gtgacaaaaa ttgtgtcacc ctctcttttt ttattgtttt ttaaagtgat
    55321 aggttggctc ctccaggttg ggatcataat caacaagtaa atcatatcct ttaaagaacc
    55381 attcatctgc ttcctcgata aaaaaaagtg tcccatccat ttccactttc tttacaggat
    55441 gttctggctg ttcaactgac attccaatcg aaaaaccatc atgaacctct gttttgccgt
    55501 agacttttcc aaaaaaacgt attccgtaag tttctggcag atcaatttct gagtcaaacc
    55561 atttttgtgc ttttggcgtt accgttaatt tcatcccaac aacctacttt ctcttttctt
    55621 tctattgatt catcttatcg tctagaatat ccacatcgcc tgtctctcca ataaccagta
    55681 gattatcatt ttcacgaaca tattcatctg ctgcaggaga agcgataacc gtttgatcta
    55741 ctcttcgtat ggcgactact gttaagtcaa aacgttgcct gaaatttaat tcagctaatg
    55801 ttttgttgaa aaatttagga ttggagactc ggatttctgc taaagaatat ttatctgaca
    55861 gctctaagta gtctagaata ttctttgata ctaagttatg tgcaatccgt atccccatgt
    55921 ctcgctcagg gtgtacgaca cgatctgctc cgatcttctc tagtacacgg gcatggtact
    55981 cattttgggc ttttgctaaa atattcggta cgcccatttc ctttaccatc agagtaacta
    56041 agatgctggc ttggatatct tctccaatag cgacaattac atgatcgaaa tttcttatac
    56101 ctaatgaacg aagtgtcatc tcatcctgtg catttgccac aacagcatgg gtggctatat
    56161 tcatatattc attgactcga tcttcattac tgtcaatagc cagtacttct tgtccagctt
    56221 cgatcagtgt acggcagatg cttccgccaa atcgtccaag gcctacaatt gcaaaatttt
    56281 gtttcaccat tttcctcctt tagtatcttc ttttctcagt ataacaaagc ctttccaaaa
    56341 acaaaagcaa gcatcattat tgtaaaaaag ccaagaaaaa taatagttat tttctcagct
    56401 tttgattatc ctctttatca tcgtttttat ttcaccaaac catgtttaaa cgcatagata
    56461 gctgcttgag ttcggtcttc tacctctaac ttagctaata tattcgacac atgcgttttg
    56521 actgttttca gtgtgataaa caattcatcc gcgatttcct gattactttt cccttcagaa
    56581 atcagcatca aaatttcatt ttctcgattc gttaattctt catgcaatac tggatcattt
    56641 cgccgactca ttttttccat catttttgtt gtcacttcag gttctagtac tcgctcgccg
    56701 cgttgcgtag cccttatagc atcagctatt tcatgtgctg tagacgtctt caacaaatat
    56761 cctgctgctc ctgcttcaat tgcaggataa actttttcat catcaataaa acttgtgacg
    56821 ataatgattt tggcttttgg ccaatctttt aagattgctt ttgttgattc gatgccatcc
    56881 atttcttcca tgactagatc cattaaaatg acatccggtc gaagtgccat cgccttttca
    56941 tagccttgac gtccattttc agcttctcca atcacttcaa tgtcttcttg gatagataaa
    57001 taagaagaga cgcctaagcg taccatttca tggtcatcta ctaataaaac ttttatcatc
    57061 tttatctatg cctccttcat caaagggacc ttggtctcca cgctcgtacc ttgcccttta
    57121 aaactaatga tttttactgt tccaccaata ccagctactc gttctttgat attgttcaat
    57181 ccataacttc ccgttttggt ttcattcata ttaaatcctg tcccgtcgtc aatgatacgt
    57241 aataaaagat tgttatctat tttatgcaaa tagacttcta attcattagc cttagcatgt
    57301 cttaatgtgt ttgataacaa ttcttgaacg attcggaaca agtgatcctc aatggaacta
    57361 gttaatttta catcttctac ctcccatttt agcgaaatct ggattttatt ctgcaattcc
    57421 ttcaataact gctcaatgcc ttgttttaaa cttttttctt ctaaattgac tggacgcaga
    57481 tgaagaagca gcgcacgcat ctcagactgg gaagcgttga tgatctctgc caccattttc
    57541 aactgcttac ggaacatttc tggtgtctca cttttttctg cttgctccgt caatgccgac
    57601 atcatcatca tcgctgcaaa taattgctgt gaaactgaat catgaagctc acgagctaat
    57661 cgatgccttt ctaattttaa aatctcttct ttggtttgtc catctacata ttgaggacgg
    57721 ctagtcataa tctgtaattc actggatact tcgatcattt tttcttttat tttagtaatt
    57781 tccatatcaa tatctttgat gtacagatca tccgacgcgc ttgggatcgg ctgatgcaaa
    57841 agtttggatt cataattgcc agaagaaagt gcacgaagct tttcttcgat tttcccgtat
    57901 tttgcctttt gaataagtga taacaataga aatacgatca atcctacacc taatgaaatt
    57961 gccatcaaat ggaagataag cggaacgtat aataaacgcg cacgcagcaa ttctccccac
    58021 caatgacttt ggttactggc ataaaaataa gtgaaaagtg aaaatagaat aataaggaaa
    58081 gccgcaatcc ccgaataaac agctagcatt gctttggata ttcttcccat catattcgta
    58141 tcacctcgac atctccaacc aaagtattgg taatgatctt caatctgcga ggattttcat
    58201 cataatcact gctgcagatt ttgatctgtt cgttttttaa ggaaaactgc tcttcttcaa
    58261 acaagacatt tcctactaat gtcgcatgct ctaaacgaat agccactccc aggggtacta
    58321 agatccgtgt tctgcctatc ccttttctta caatcacaat attatcatct tttggcaaaa
    58381 gtgtattgcc caaatcgatg atagtatcac cagaaatgat ggcaatgttg atatcatccc
    58441 attcatagac gtcgtttcca atacgttggt taccaaataa ttgctgtctt ttacgctcat
    58501 tattatgtgt ttttaattgc tctgtttgga ccatcatgat ctgttttttt cgccaaaaag
    58561 cattttttgt caaatctatt cctgaaatct ctacaccttt cagcccgata aataaaacgg
    58621 ccaatacaac catcatccat aaagcaggac tgttgactaa gctaaaaaaa atgaccaagc
    58681 tccctaagat caattgaaaa ttttgaaatt tagtacgagg atatttgcgc atagctagat
    58741 atatattgaa aataccgaat attactaaaa gcaaaagtcc agtattgttt acgatttgcc
    58801 aaacagcaaa taacagcagc agtgcttcga ctaccacaaa aaaacgccaa gaactattca
    58861 tcgctttttc tccctcctga cacattctca tttcatcata cctatttttt tgactgttgg
    58921 ctataggact ttagatgtaa gatcgttcag tgaaacctgc aatactcaaa gagaaaagat
    58981 ctagagtgcg tcatcagtaa gatgaactct ctagatcttt cagtcagact acgcttgttc
    59041 tactttgacg attttaacta acatatcgcc acctggtgta gcaatggtta cttcatcatt
    59101 tttacgtttg ccaatcaatg cttgcgcgat aggagaatca ttggaaatct ttccagaaaa
    59161 cgggtctgct tcagcacttc cgacaatcgt gtactcttct tcatctccat caggcaactc
    59221 gatgaacgta actgttttac cgatcgatac ctcatctgca tctacgccgt cattatcgat
    59281 gatttgtgca aaacggatca tattttcaat tgttgtgatt cttccttcaa caaatgcttg
    59341 ttcatcttta gctgattcgt attcggagtt ttcggaaaga tctccgaaac cgcgagcgat
    59401 tttgattcgt tcaatgattt ctccgcgttt aactgttttt agttcttcta attctttttc
    59461 taatttttct ttaccttcta gagtcattgg ataaactttc tctaccatgt gtaacgtctc
    59521 cttttttcga taaaataccg caaaaggtaa tcttttgagg aatatagtcc aaaaaagatt
    59581 accacgcttt tcttaaaatg taaatgtttt tctaaaaatg atcaatgact agcccctgtt
    59641 tttctaagaa ttatttacat atttttgcac tagttccata tgttcttcat acgttttagc
    59701 gaaataaaca tttccagtgc tcgtatctgc tacgaaataa taatagtcat tttctgctgg
    59761 ttctaatact gccttgattg cctcttcgct tggattgtca aaaggaccag gcccatagcc
    59821 ggtattggta tacaaattgt atggtgaatc tacagctgta tcttcatacg tcaccaattc
    59881 tttatgttct cctaatgcat ataaaacaga gatatctgac tgaagtggca tatttgcctt
    59941 gattcggtta aagaagactt gtgcaatatt tttacgatca ttttctttta cgccttcttt
    60001 ttcaactaga gaagccaaag ttaaaacttc ttgtacagtc aaatttttct gtttgatagc
    60061 tgaataatag ttttgcatga ccgtatttgt tttgttcacc atctcaatca caagatcctt
    60121 aagcgaagta ctcgtgtagt aatcataagt agctgggaat aagtagcctt ccaaacggta
    60181 ttttgtgttc tcagctttag aggcactttc caacaattct gggaattttt gatacaactc
    60241 gttaaagaaa gtctcatcat ttactaaatc taaaaattct ttcttgtctt taccagttac
    60301 cttcgctacc cgctcagcaa tctgatcgat gtcgtagcct tctggaatgg caattttccc
    60361 atctgcaact tttgttggct cagaagtgcc gccttcttgc agctgtttgc caatctcgtc
    60421 aagagtcata ttaggcgcta actgataata gccagcttga aagccagtta aatttttaaa
    60481 ttttgtataa taattgaaaa caatcccgct tttaataata ttgtccttct ccaaaatctc
    60541 accaatctgc ttgttagaag agccactcgg gatctccact tggactaatt ggtcatctga
    60601 tttatctaaa ggcttcaacc cgctatctac ataacgatac acggtaaatc caagaaatcc
    60661 gccaataatt aataatgtaa gagcaatcac taaaatgatc ttcctcacaa tcttatcttc
    60721 ttttttacgc agatttctcc gcttgtcgat tatatctgct gtagctgcct tactggcttc
    60781 ttttttatct ttacttgggt gttgtttgtt tcctgacaaa acaactcctc cttactatca
    60841 tcttcgtaac tctgtttatt atacatgaaa tttctactgc cgtgaattat tttaccaaat
    60901 attatgtcaa aattgtaagt ggcaaatact ctttttgagg attacaatga aaaatagtta
    60961 aaaatggata gaaaggaatt aacatgtcaa aaggaaaaca tcgaaaaaaa caaaaaattt
    61021 ctatttcttt tcttgtaatt ttattattgt ctgtcagctt cttttcaaca ggcatcatta
    61081 taggaggtca attaacaaaa atacctcatt cccaaactta taaagcggag ccaacacaac
    61141 ttacttccaa tttaacgccc gatgagcaga ggcttgctag caaaattgat caattactac
    61201 aaaaatcaga ttatatcggt tcgatttatg ttcgcaaaaa taatcgcgta ctattagaaa
    61261 aaggatatgg atatgcaaat ctgcgcgtaa aagaatcgaa ttcaccttct atttactatc
    61321 aaatcggttc gattcaaaaa gcaatgactg ctttactgat actaaaacaa atccaagctg
    61381 gtaagttaac ttttgacaca aagttagcag aattttatcc tcagattcct ggaagtcagc
    61441 aaatcacaat caaaaatatg ctttatatgc gctctggtct tcatcgaact gcttctcccg
    61501 acaaacctat gtcggatagt gaaatcattc agttcgccct tcatcatttg aaacttactg
    61561 attatgatac gtatcattat gaaccattga attatacatt gcttacaggg atattgatca
    61621 aactaacgaa tcagccttat gaaactcttc taaaaaaaga aatcattcgt ccactccatc
    61681 tagaacatac agatttttat gacaatgtaa aaaattcgcc tcaacatgct gtatcttacc
    61741 agatgtctgc aactgacgat tattcaaaag cattgatcga gcctgaaacc gacatccgaa
    61801 atgaattagg tacaggaaac ataagtatgt ctgtttatga cttgaacaaa ttctttacca
    61861 gtgttctttc tggcggtatc ataccaaaag aactactttt ctcattgtgg caaaataatg
    61921 gtgataaaca tccttacagc ggcggtgttt acagtggaaa cgattatatc cttgctcagg
    61981 ggaatatcaa tcgattccat gcagtagtgg cgatgaaaaa agacactaaa gatgcaatcg
    62041 tcatggaaag taatatccaa tcggataaga acatcaaatt gccggccact gatttaagaa
    62101 atcagattta tgaactgatg gaaggtgttc acttatcaaa ttaaattttg acataatatt
    62161 agttgtcatc tctgtatagt caatttagtt agtactctat ctgaaaagta gaaataaatt
    62221 aacaaatatt atctgtcctt attatttgtt aatttatttc ttattttact
//
LOCUS       DAPBCF010000010        59945 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.010, whole genome shotgun sequence.
ACCESSION   DAPBCF010000010 DAPBCF010000000
VERSION     DAPBCF010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 59945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.010"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(135..512)
                     /locus_tag="RD508_000811"
     CDS             complement(135..512)
                     /locus_tag="RD508_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735426.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            768..1496
                     /locus_tag="RD508_000812"
     CDS             768..1496
                     /locus_tag="RD508_000812"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDT7735427.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1496..1750
                     /gene="purS"
                     /locus_tag="RD508_000813"
     CDS             1496..1750
                     /gene="purS"
                     /locus_tag="RD508_000813"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HDT7735428.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1752..2423
                     /gene="purQ"
                     /locus_tag="RD508_000814"
     CDS             1752..2423
                     /gene="purQ"
                     /locus_tag="RD508_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HDT7735429.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2424..4646
                     /gene="purL"
                     /locus_tag="RD508_000815"
     CDS             2424..4646
                     /gene="purL"
                     /locus_tag="RD508_000815"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HDT7735430.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYELMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4631..6070
                     /locus_tag="RD508_000816"
     CDS             4631..6070
                     /locus_tag="RD508_000816"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDT7735431.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6093..7145
                     /locus_tag="RD508_000817"
     CDS             6093..7145
                     /locus_tag="RD508_000817"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDT7735432.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7142..7720
                     /gene="purN"
                     /locus_tag="RD508_000818"
     CDS             7142..7720
                     /gene="purN"
                     /locus_tag="RD508_000818"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDT7735433.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7717..9252
                     /gene="purH"
                     /locus_tag="RD508_000819"
     CDS             7717..9252
                     /gene="purH"
                     /locus_tag="RD508_000819"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDT7735434.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9268..10542
                     /gene="purD"
                     /locus_tag="RD508_000820"
     CDS             9268..10542
                     /gene="purD"
                     /locus_tag="RD508_000820"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDT7735435.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10664..11578
                     /locus_tag="RD508_000821"
     CDS             10664..11578
                     /locus_tag="RD508_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7735436.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11711..13276)
                     /locus_tag="RD508_000822"
     CDS             complement(11711..13276)
                     /locus_tag="RD508_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDT7735437.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13269..14720)
                     /locus_tag="RD508_000823"
     CDS             complement(13269..14720)
                     /locus_tag="RD508_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7735438.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14734..15750)
                     /locus_tag="RD508_000824"
     CDS             complement(14734..15750)
                     /locus_tag="RD508_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7735439.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15970..17058
                     /locus_tag="RD508_000825"
     CDS             15970..17058
                     /locus_tag="RD508_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HDT7735440.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17112..18638
                     /locus_tag="RD508_000826"
     CDS             17112..18638
                     /locus_tag="RD508_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDT7735441.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18640..19845
                     /locus_tag="RD508_000827"
     CDS             18640..19845
                     /locus_tag="RD508_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7735442.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20102..21079
                     /gene="guaC"
                     /locus_tag="RD508_000828"
     CDS             20102..21079
                     /gene="guaC"
                     /locus_tag="RD508_000828"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HDT7735443.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21343..22767
                     /locus_tag="RD508_000829"
     CDS             21343..22767
                     /locus_tag="RD508_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDT7735444.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23228..24337
                     /gene="pdhA"
                     /locus_tag="RD508_000830"
     CDS             23228..24337
                     /gene="pdhA"
                     /locus_tag="RD508_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HDT7735445.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24340..25317
                     /locus_tag="RD508_000831"
     CDS             24340..25317
                     /locus_tag="RD508_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDT7735446.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25342..26985
                     /locus_tag="RD508_000832"
     CDS             25342..26985
                     /locus_tag="RD508_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HDT7735447.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26993..28399
                     /gene="lpdA"
                     /locus_tag="RD508_000833"
     CDS             26993..28399
                     /gene="lpdA"
                     /locus_tag="RD508_000833"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDT7735448.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            28561..28836
                     /locus_tag="RD508_000834"
     CDS             28561..28836
                     /locus_tag="RD508_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HDT7735449.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            28842..29609
                     /locus_tag="RD508_000835"
     CDS             28842..29609
                     /locus_tag="RD508_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HDT7735450.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29777..31606
                     /gene="typA"
                     /locus_tag="RD508_000836"
     CDS             29777..31606
                     /gene="typA"
                     /locus_tag="RD508_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HDT7735451.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31867..33639
                     /gene="recQ"
                     /locus_tag="RD508_000837"
     CDS             31867..33639
                     /gene="recQ"
                     /locus_tag="RD508_000837"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HDT7735452.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            33753..34055
                     /locus_tag="RD508_000838"
     CDS             33753..34055
                     /locus_tag="RD508_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HDT7735453.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            34058..35221
                     /locus_tag="RD508_000839"
     CDS             34058..35221
                     /locus_tag="RD508_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDT7735454.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            35247..38675
                     /locus_tag="RD508_000840"
     CDS             35247..38675
                     /locus_tag="RD508_000840"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HDT7735455.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38696..39820
                     /locus_tag="RD508_000841"
     CDS             38696..39820
                     /locus_tag="RD508_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735456.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39810..40247
                     /locus_tag="RD508_000842"
     CDS             39810..40247
                     /locus_tag="RD508_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDT7735457.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            40231..40569
                     /locus_tag="RD508_000843"
     CDS             40231..40569
                     /locus_tag="RD508_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HDT7735458.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40688..41248
                     /gene="rsmD"
                     /locus_tag="RD508_000844"
     CDS             40688..41248
                     /gene="rsmD"
                     /locus_tag="RD508_000844"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HDT7735459.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            41245..41736
                     /gene="coaD"
                     /locus_tag="RD508_000845"
     CDS             41245..41736
                     /gene="coaD"
                     /locus_tag="RD508_000845"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDT7735460.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41726..42769
                     /locus_tag="RD508_000846"
     CDS             41726..42769
                     /locus_tag="RD508_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HDT7735461.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            42928..43656
                     /locus_tag="RD508_000847"
     CDS             42928..43656
                     /locus_tag="RD508_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HDT7735462.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            43772..44017
                     /locus_tag="RD508_000848"
     CDS             43772..44017
                     /locus_tag="RD508_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDT7735463.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            44014..44232
                     /locus_tag="RD508_000849"
     CDS             44014..44232
                     /locus_tag="RD508_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDT7735464.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            44368..44907
                     /locus_tag="RD508_000850"
     CDS             44368..44907
                     /locus_tag="RD508_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HDT7735465.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            44900..47173
                     /locus_tag="RD508_000851"
     CDS             44900..47173
                     /locus_tag="RD508_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HDT7735466.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            47211..48257
                     /gene="holA"
                     /locus_tag="RD508_000852"
     CDS             47211..48257
                     /gene="holA"
                     /locus_tag="RD508_000852"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDT7735467.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(48346..48600)
                     /locus_tag="RD508_000853"
     CDS             complement(48346..48600)
                     /locus_tag="RD508_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDT7735468.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(49000..49269)
                     /locus_tag="RD508_000854"
     CDS             complement(49000..49269)
                     /locus_tag="RD508_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735469.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(49739..50194)
                     /locus_tag="RD508_000855"
     CDS             complement(49739..50194)
                     /locus_tag="RD508_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HDT7735470.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(50332..52260)
                     /locus_tag="RD508_000856"
     CDS             complement(50332..52260)
                     /locus_tag="RD508_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDT7735471.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(52457..53290)
                     /locus_tag="RD508_000857"
     CDS             complement(52457..53290)
                     /locus_tag="RD508_000857"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDT7735472.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(53482..54186)
                     /locus_tag="RD508_000858"
     CDS             complement(53482..54186)
                     /locus_tag="RD508_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7735473.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(54209..54835)
                     /locus_tag="RD508_000859"
     CDS             complement(54209..54835)
                     /locus_tag="RD508_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDT7735474.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            55161..57536
                     /locus_tag="RD508_000860"
     CDS             55161..57536
                     /locus_tag="RD508_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HDT7735475.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(57560..58051)
                     /locus_tag="RD508_000861"
     CDS             complement(57560..58051)
                     /locus_tag="RD508_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HDT7735476.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            58238..59158
                     /locus_tag="RD508_000862"
     CDS             58238..59158
                     /locus_tag="RD508_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7735477.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            59312..59656
                     /locus_tag="RD508_000863"
     CDS             59312..59656
                     /locus_tag="RD508_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HDT7735478.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(59846..>59945)
                     /locus_tag="RD508_000864"
     CDS             complement(59846..>59945)
                     /locus_tag="RD508_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7735479.1"
                     /translation="KKNLGSLKAQQKNGAAIYREDEKEYYTKIKLM"
BASE COUNT        19670 a        10365 c        12872 g        17038 t
ORIGIN      
        1 aaccaaaaaa gaagcagatc cgttagcggt tctgcttctt ttagtttatt atattttctt
       61 atcaataata ggaacctgat tttaaaagcg gctacctctt taccgtgcct ctttacatac
      121 aaaaaataga ggaattaagc gtaaatggct tggctattat aactaaaatg ctggttatgg
      181 agatgttgca gcaagttttc gagaaaagcg tattccatct cttgtccatt gaataagatc
      241 tggatacgat aatgattttt gaaacgcttc tgttcatgaa tctgactgat tgaaagttcg
      301 cctttgtgtt ctgtctgata aagaaaagtc cttttacggc attcagcaca gcgcttggtt
      361 gctcggcgga tttttcggaa tgtataaaaa ctagtatctt tattgcataa ataaacgtct
      421 ttgatcgaca gcaaatcatt atatagacag gaacgttctt cagctgttaa ttctgataaa
      481 aaaagctgac cttgttttat tgcatcttcc atcggcaagt gcctcctcga acccattatc
      541 caaattttta gttaattcta atataccatc attaagtata aatgtaaacg cttgttgatg
      601 gtataagatt ttcgtttctg ataaaacacg aacattaaaa gaatctaatg ccttaaatgt
      661 acatattttt gttgatttat aaaaagatga ttgctaaaat ttaaagtgaa aaaacgaaca
      721 aaaaacgatg tatttgcttt taatgtaaat aaaaaggaga gacgtacatg gagaagaaag
      781 aacttttgta tgaaggaaaa gccaaaaaaa tatatcttac ttctgatgag aacttgattt
      841 ggatagaata tttagatcaa gcaactgcgt tgaatggcgc gaggaaagac cagataagtg
      901 gaaaaggaga attgaataat caaatcacaa gtgcaatttt ccgttatctg actcaaagag
      961 gaataaaaaa tcattttatt gaacaattgt ctaaaaccga acaattagca aaaaaagtac
     1021 aaattatccc tctggaagtg gttatccgaa atattgcagc aggaagtttc tcaaaacgtc
     1081 taggtgttcc cgaaggtaaa gaattcatca aaccaatcat tgaattctac tataaggatg
     1141 accagttgga tgatccattt atcaatgaag agcatatcta tttcttacaa cttgcaaagc
     1201 cggaagaaat cagtgagctg aaagcccaag cgttggctat taatgaaatt ttgaccgaat
     1261 tatttgctaa ggtcggtttg gttttagtag atttcaagct agaatttggc cggtcgaatg
     1321 gacaaatttt gcttgcggat gaagtaacac cggatacttg ccgattatgg gatgaacgta
     1381 cgaatgaaca tatggacaaa gacgtttacc gcagagatct aggtgatttg atcccagtct
     1441 atcaagaagt atataaccgt ctatcggaac taactgaaga aaaggagcga gtatgatgta
     1501 tttcgtaaaa gtatatgtaa cctataaaga ttcagtgtta gatcctcaag gggaggcagt
     1561 aaaaaaagca gtccatcgta tgggatatga aacaatcgaa gatatccgaa taggaaaata
     1621 ctttgagata caacttgctg atgcagaaga accaatcgat acagtgattg aaacgatttg
     1681 tgacaagctg cttgcaaatg taaatatgga aacataccga tatgaaatca aaaaaatgga
     1741 ggaagtataa catgaaattt gcggtcatcg tttttccagg ttcaaattgt gacgcagata
     1801 tgttatgggc agttcgcgag atcatgggcg ctgatgccga atttgtacgg catgatgagt
     1861 cctctttaga aggatttgat ggggttttac tgccgggagg attctcctat ggtgactatt
     1921 tgagatgcgg tgcgattgct cggttttcta caatcatgga agaagtgatt cgttttgctg
     1981 aagaagggaa accagtattc ggtacatgca atggattcca gatattgaca gaagcaggac
     2041 ttttgccagg tgtactgaga cgaaatgagt ctttgcattt tatttgcaaa actgtaccat
     2101 tgaaagtcaa ccccaagacg gcctttactt cagagtatga agccgacgaa ataatctatc
     2161 ttccagttgc tcatggggaa ggaaattatt tctgtgacga agaaacactt caagaactaa
     2221 aaaaaaataa tcagattgcc tttacttata atgacaacat caacggcagc gtggaaaaca
     2281 ttgcagggat tacgaacaaa gcagggaatg tgttaggaat gatgcctcat ccagaacgtg
     2341 cagtagaaga cttgctagga tcagaagatg ggaaacggtt ctttgcttcc attttaaaaa
     2401 acttcggaaa ggtgaccgta tagatgaaaa cattgaaaga accgacagct gaagagatca
     2461 agaaaaaaag aatctatgcc gaatggggat tgactgatga agaatatcga atgatcgaag
     2521 aagatatctt aggaagaatg cctaattata cggaaactgg actgttttct gttatgtgga
     2581 gcgaacattg ttcctataaa aattctaaac cggttctacg caaatttcct actagtggac
     2641 ctcatgtgtt gcaaggccct ggagaaggcg caggcatcgt cgacatcggt gatggactag
     2701 cagttgtctt caaagcagaa agtcacaatc atccttcagc cgtggagcct tatgaaggag
     2761 ctgcgacagg agttggcgga atcatcagag atattttcag catgggggct cgtccaattg
     2821 cgttgctaga ttcattgagg ttcggcgaat tagataatcc aagaacgaaa tatttactag
     2881 aagaagtagt tgcaggtatc ggcggatacg gcaattgtat cggcataccg actgtaggcg
     2941 gcgaaattgc atttgatcct tgttatgaag gaaacccatt agtcaatgca atgtgcgtag
     3001 gtttgattga acacaaacat atccagaaag ggcaagccgc tggcgtcggt aattcgatca
     3061 tgtatgtagg tgcaaaaaca ggtcgcgacg gtatccacgg agcaactttt gcctcagaag
     3121 aatttaatca agaagaagaa cagcaacgtt ctgctgtaca agtaggcgat ccttttatgg
     3181 aaaagctgct gcttgaagcg tgtttggaat taatcttgca tcattcggat tctctaatag
     3241 gtatacagga tatgggagca gcaggacttg tttcatctag tgcggaaatg gcttcaaaag
     3301 ctggctcagg acttatattg acattagatg aagtcccaca aagagaaact gggatgacac
     3361 cttatgaact gatgttatcg gaatcacaag aacggatgtt gatttgtgtt aaatcaggag
     3421 aggaagaaaa aatccaagaa ctatttcaga agtatgatct agatgcagtc actatcggta
     3481 aagtaacaga cgacgggcaa tatcggctat atcatcaagg agaagaagta gcaaatctgc
     3541 cagtcgatgc attagctgaa gatgcaccag tttatcataa agaaatgaaa gaaccagctc
     3601 gaatcgtaga atttcagcag ttagctcctt atcagccagt tatcgaagaa cctggacaag
     3661 tattgcttga tctgctgcag caaccgacga ttgcttcaaa acgttcaatc tacgaaactt
     3721 atgattcaca agtacaaacc aatacagttg tccgtccagg aagcgatgct gctgtgatga
     3781 gggttagagg gacgaataaa gcgttagcta tgaccacaga ctgcaacgcg cgctatctgt
     3841 atttggatcc aaaaatcgga ggacaaatag cagtggcaga agctgctaga aatattattg
     3901 ctagcggtgg taagcccttg gcgatcaccg actgcctgaa ctatggttct cctgataaac
     3961 cagaagtttt ttgggaatta tcgacttcag ctgacggaat tgctgctgcg tgtgaaacgt
     4021 taggaactcc tgttatttca ggaaatgtct ctttatataa tgaaacggat ggtcaagcaa
     4081 tctatccaac accaatgatt ggtatggtcg gattgattga ggatcataaa catatcacta
     4141 ctcaggaatt caaaaaatca ggggatctaa tctatatatt aggtaagacg tttgcagatt
     4201 ttgatggcag tgaattacaa aagatgcagc ttggaagaat cgaaggtgtg atccgaaact
     4261 ttgatctatc cattgaaaag agaaaccaag agttagtatt gacagccatc caaaacggat
     4321 tgattgaaag tgctcatgac tgttcagaag gtggcttggc aattgcactg gcagaatcag
     4381 ctttcaaaca tcagctaggg atatctgtac agtttgaatt gtcctctgct caattatttg
     4441 cagaaactca atcaagattt gtgttgacag tcgcaccgga aaataagaca cgattcgaag
     4501 aaatgatggg agatgctgct gttttagcag gtaaggtgac ggatgaagcg ataatcgaaa
     4561 tttcagcaac tgacggtcag atcaaaatag aaactgcagt agcaagaaag tgctgggagg
     4621 atgcaatcgt atgtcttatg aagtgaagag tttaaatgaa gaatgcggga tcttcggtgt
     4681 ttggggtcat ccagacgccg ctagtgtggc atacttcggg ctccatagtc ttcagcatcg
     4741 aggacaagaa ggtgcaggta tcgtgtccaa tgatcgagga aagcttaagg ggcatcgaga
     4801 tttggggctg ctttctgagg tattcaaaga tcaaagaaaa ttgcagcagt taacaggaga
     4861 agctgcaatc ggacatgtac gttatgcaac agcaggcaat ggaagtgtgg acaatattca
     4921 gccttttcta ttcaaatttc atgatcagtc gatcggctta gcgcataatg gtaacttgat
     4981 caatgctcgt tcccttagaa aagagttaga ggaaaatggg gcgatcttcc attctaactc
     5041 cgatacggag atattgatgc atttgatccg acgaagtgaa gaaacagatt ttttaaataa
     5101 attaaaaagt gctttgaatg aagtcaaagg tggctttgcc tatttattaa tgacagaaac
     5161 ggcaatgatt gccgctttgg acccaaatgg ttttcgtcca ttagcaatcg gacaaatgaa
     5221 aaacggagca tacgtgattg cctcggaaac ttgtgcatta gaagttattg gggcacgttt
     5281 tataagagat gtccagcctg gtgagatagt gatcatcaat gacgaaggaa tccagattga
     5341 ttgctttacg aaggacacgc agctttctat ttgttcgatg gaatatatct attttgccag
     5401 accagattca aacatcgcag ggatcaatgt gcatactgca cggaaaaata tgggacggaa
     5461 tttagcgaaa gaatcgccag taaaagcaga tatggtcgtt ggcgtaccta attcttcttt
     5521 gtcagccgca agcggttatg cggaagctag tggaatccct tatgaaatcg gattagtaaa
     5581 aaatcaatac attgcccgaa catttatcca gccaacgcct gagctaagag agcaaggtgt
     5641 tcgaatgaaa ttatctgctg tacgaggagt agtggaaggt aaaaaggtga ttatggtcga
     5701 tgattcaatt gttcggggta cgacaagcag acggatcgtc catcttttga aagaagcagg
     5761 ggcaaaagaa gtccatgtga ggattgcttc tcctcctttg aaatatccat gtttttacgg
     5821 gattgatatt caaacgcgta aagaactcat tgcggcaaat cacacgattg atgaaatcaa
     5881 agaatgtatc ggtgcagatt ctttaggttt tttaagtgaa gagggtctga tcgaatcgat
     5941 cggtctggaa aaagatgctc cgtattcagg attgtgtatg gcttatttca acggagatta
     6001 tccgacgccg ttatatgact atgaagaaaa atatcaggaa tcactaaaag aaaaagtatc
     6061 gttcttttaa aagcagacca agaagggagt atatgaattc aatggcaaat gcatacgcaa
     6121 aagctggcgt agatgtcgaa gctggatatg aagtagtaga acggatcaag aagcatgtca
     6181 aaaaaacgga acgtttaggt atgatgggcg ctataggagg attcggcggt tgttttgatt
     6241 tatcggtctt tcaattaaaa gagccagtcc ttgtctcggg gaccgatggc gtggggacga
     6301 aattagcagt ggcaatcgaa gcagacaaac acgatacaat cgggatcgac tgcgtagcga
     6361 tgtgtgtcaa tgatatctta gcacaaggcg cagagccgtt atatttctta gactacttag
     6421 caacggggaa aaatgatccg ttacgtttgg aaaatgtagt aaaaggtgta gcagatggat
     6481 gtgttcaagg aaatatggcg ctgattggcg gagaaacagc tgaaatgcct ggtatgtact
     6541 caggtaatga ttatgatcta gccggatttg ctgtagggat agctgaaaaa tctcaattat
     6601 tgacaggaga aacgatcaac ccaggagatg tgttgcttgg aatagcatct agcgggattc
     6661 attcaaatgg gtactctctt gttcgcaaaa ttttctttga gcagcagcag ttttctttat
     6721 catcaaaact gccagaattg aaaaaaacac ttggcgaaga attgcttgag ccaacgaaaa
     6781 tctatgtttc ttccttgctt ccgctgatca aagaaaagaa aataaaagga gctgcacata
     6841 tcactggtgg agggtttgta gaaaatatcc cgcgaatgtt accagaatct atggctgcac
     6901 aaatcaaact tggctcatgg ccgattcttc caatattcgg ctgtttacaa aaatatggtg
     6961 aaattcctga gatggagatg tatgaaatct tcaatatggg catcggtatg gtcctggcag
     7021 tcgaagaatc gaaagtaaaa gaaatagtac acgaaattga gcaagctggc gaaaaagttt
     7081 atgaaatcgg gaaagtgatc gccaaagaaa aacatcgtgt ggtgtttata ggagaagaac
     7141 gatgagaatc gctgtttttg cttctggaaa cggaagcaac tttcaagcgc tagccgatta
     7201 tctatcgaaa aaaggattgg aatcttcgat tgactggttg ttttgtgatc agcctgaagc
     7261 atatgttttg aaacgtgcaa ctgcgttgag tgtaccggca gattgttttt cacctaaaga
     7321 atttgattca aaaaaagagt atgaagaagc aattttgcat aaattgaaag aaaaaaagat
     7381 cgatttgatc gtattagctg gatatatgcg aatcattgga ccggtattgc tgaaaaatta
     7441 tgataaaaga atcatcaata tccatccgtc tcttttacct gccttccctg gtttgcatgg
     7501 catacgtgat gcctttgaag ctggagtaaa agaaacgggt gtcacaattc attatatcga
     7561 ccaaggtgta gatactggac caatcatccg gcaggaaaaa gtgagaattg aacaggagga
     7621 cacgttcgat tctttagaag aaaaaatcca tagagtagag catcgaatct atccagaagt
     7681 gattagtgaa attattgaaa atggaggcta tctgaaatga caagagcatt gatcagtgta
     7741 tcagataaaa ctgggattgt agcattcgcc caaggtttga ttgaacaagg agtagaaatc
     7801 atttcaacag gaggaacaaa gcatgcgttg gataaagctg ggatcaaaac gctttcgatc
     7861 gaagaagtga cagggtttcc tgaaatgatg gatggccgtg tcaaaacact tcatcctaaa
     7921 atccatggtg gtcttttagg aagacgcgat ctccctagcc atatggaggc aatggaaacg
     7981 gaaaatatcc aaccaatcga ctttgtttgt gtcaatttat atcctttcaa agaaacgatt
     8041 atgaaaccag atgtcgaaat agcagaagct attgaaaaca ttgatatcgg tggtcctagt
     8101 atgctccgta gtgcagcaaa aaaccatgaa tttgtcacct ctgttgttga tccatctgac
     8161 tatgaagaag tactttcaga attacgtcag tatgggcata cttcactttc tttcagacaa
     8221 aaactagcgg caaaagtctt tcgtcatact gcggcatatg atgcactgat cgctcaatac
     8281 ttaacggatt gggtggaaga aaaagaaccg gaaaaattga cacttacgta tgaacgaaaa
     8341 caaacgcttc gttacggtga aaatagccat caagccgctg ccttttatca gtccgctctt
     8401 ctggaaaaat attcgatcgc agcagcaaaa caactccatg ggaaagaact ttcttataat
     8461 aatatccgag atgcagatgc tgcgctacgg atcatgaagg aatatgacga gccaacggta
     8521 gtcgccttga aacacatgaa tccttgtggt attgggacag catctacgat tttagaagcg
     8581 tgggaagcag cgtatgaagc agatcctgtt tcaatctttg gtgggatcat cgttttgaat
     8641 cgagaagtag atctgccaac agcagaacag atgcataaac tgtttctaga aatcatcatt
     8701 gccccttctt atacacaaga agctttggaa ttactgcaaa aaaagaaaaa catccgatta
     8761 ctgacagtag actttgcgca ggaagaaaat caaaatcgag aagaaacggt ctcagtctta
     8821 ggtggacttc ttgtacaaga tcaagatctg gcaatagaaa atgaagaaga gtggaaagtc
     8881 gtgacaaaac gtaagccgac tccagcagaa gcaaaagcat tagcgtttgc ttggagagct
     8941 gtcaaacatg tgaaatctaa tgcgatcgta ctggcaaacg aacgtcagac agtaggaatc
     9001 ggagccgggc agatgaatcg agtcggttca gtaaaaattg cgattgaaca agcgcaagag
     9061 aaaatggaag gtgcagtttt agctagcgat gcttattttc caatggatga ttcggttgaa
     9121 tatgcagcca aacatggtat aaaagcaatc attcagccag gaggaagcat caaagaccaa
     9181 gattctattg atatggcgaa taaatacgat ctagcaatgg tctttactga tgttcggcat
     9241 tttagacatt agagaggagt cggataaatg aacattttgg tgatcggtgc aggtggtcgt
     9301 gaacatgcaa taagtaaaaa acttttagcc agtccgaagg tggatacggt gtattgtgcg
     9361 ccaggaaatc cggggatgac aaaagatggt atcaattgtg tcgctatcag tgagcgagat
     9421 cattcagcgt taatccattt tgttaagaaa gaggctattg attggagtat cgttggtcct
     9481 gaagttcctt tgttaaatgg gatcgtcgat gattttatgg cggaaggatt gaaaatcttc
     9541 ggtccgacaa aagcagcagc tctgatcgaa ggttcgaaaa gttttgctaa acaattaatg
     9601 gatacttatc aaatcccgac agctaaatcc agaagttttg aatgttacga aaaagcagca
     9661 gcgtatatca aagaaaatgg tgcgccaatc gtagtgaaag cggacggctt agcagctggg
     9721 aaaggtgtag tcgtggctac cacagtgaag gaagcgctgg atgcggcaga acaaatgttg
     9781 aaccagcatc gatttgggga tagtagcaaa aaaatcgtcg tagaagagtt tttggcagga
     9841 gaagaattct cccttttggc gtttgtccgt aataccaagg tgtatccgat ggtcatttcg
     9901 caagatcata agcgggcatt tgataacgat aaagggccaa atacaggcgg aatgggtgct
     9961 tattcaccag taccgcaaat ttcaaaaaag atgattgaaa aagctgtgga agaagtttta
    10021 aaaccagcgg ctttgggaat gaaagaacta ggacgctctt tcacgggtgt tttatatgcg
    10081 ggtttgattg ctacgaagga aggaccaaaa gtgatcgaat tcaatgcgcg tttcggtgat
    10141 cctgaaacgc aagtcgttct ttctcggttg aagagtgact ttgcgcaagt aatcgatgat
    10201 ttattagaga atcgtacagt agagttaaag tggcagcaag aaggatacaa tgtaggcgtt
    10261 gtggttgcag ctgccggtta ccccgaagaa tatgagacag gaatggttct accagatttt
    10321 ctggaagaag agctttctgt ttactatgct ggagtttcct caaataacgg caaactagtt
    10381 ggagcaggag gacgtcttta tttagtagaa gcatacggtg agacgatcaa agaagcacag
    10441 aaaaaaattt acaccgcgtt aatggataaa acgacagatg gaacatttta tcgtacagat
    10501 attggagaaa aagctgccaa tagcgaactg atcgtgaagt aaatcagctg cttccattta
    10561 taaaaaatac aacaaacata atcggaagcg ccgattttag tgaagccttt tcataaagag
    10621 tgtggtacac ttttgttgtg tatataaata aggaggagtt cagatgaaaa aaattcaatt
    10681 aggtacttct gatcagaaag cagctgcagt gatcttaggc tgtatgcgta tcaacaatgc
    10741 ggaagatcca gtaaaagtga ttgagacagc ttatgaaaac ggcattgatt tttttgacca
    10801 tgcagatatt tatggaaacg gtgaatgtga agaaatcttt gcagatgctc tagcaaaaac
    10861 atcaatcaaa cgagaagatc tttttattca aacaaaatgt ggaatcgttc caggtgtgat
    10921 gtttgatttt tctaaaaaac atatcattga atctgtagaa aaaagtttga cccgtctgaa
    10981 aatggattat gtggatgctt tacttcttca tcgtccagat acattggtag aaccagagga
    11041 agtagctgaa gcgtttgatg aattggaacg gtcaggaaaa gttcgttatt ttggcgtcag
    11101 caatcaaaaa ccaatgcaaa tcgaattgct gaaaaaatat gttcgtcaac cattagtagc
    11161 taatcagctg caatttggct tgaaacatac tggaatgatc gatcaaggga ttcatgtcaa
    11221 tatgacagat gaagcaagta tcgatcatga cggtagtgta cttgattatt cccgattgca
    11281 tgatatgacg atccaagcat ggtcaccata ccagtatgga ttttttgaag gtgtatttat
    11341 cgggaacgaa aaattccctg aattaaacca aacattagaa gaactagcag ctaaatatca
    11401 aacgacacca actggcttgg cttctgcttg gattttacgc catccagcca atatgcaagt
    11461 gatcgccggt acgatgaacg tagggcgaat caaggaaatc gctcaagctt cagaaattaa
    11521 tatgtctcgg gaagattggt acgaattgta ccgtgctgct ggaaacattt taccttaaag
    11581 attgtcataa gcaggtcaaa agggctataa attaaaaaga cagaataact tgaaagctgt
    11641 tttcagcttc gagatattct gtcttttttt attgcaaatg gaaagagtat cattgtacgg
    11701 atttcgttta ttagttattt ttgtttttaa ggaaaagctg tgtccgatat tcttttggag
    11761 aaatcccttg ttttttctta aataaataac tgaaatagtt agggtcatta taaccaattt
    11821 caaaagcaat atctgaaata cgatagtctg attgctgcaa taattttttt gctaattcga
    11881 ttctttgttc tgtcagataa tcgatgaatg tttggttaaa cgattgagaa aaaatcgtac
    11941 tgaaatgaga gggacttaat gcaacttgtt gagcgaccca agttaaggac atatctggat
    12001 cggtaaaatt ttctttgata aaatccaatg catggttcaa aattggctga tatttgttcc
    12061 ttgaaggctg tgagggcaga gcagttaaga aagaaatgaa catataaact gtcgaacggt
    12121 aaagcgagtc gtcggcgctg attgctaagc gttgactggt ggatgtgcaa tgaaccattt
    12181 cttgcgggat tttcttttct ttcaggcaga catgctggag tagcttagtc aagacaaata
    12241 aacgatataa tcgtgttcga gttggtgtgc cttgtggttt cgtcaagtgt tcgatgtact
    12301 tagatacttc gtttttcgat aatgaagaca aatcaagtga gaggtcaaag taaaagacag
    12361 aatcaactgg aagtttcgct tcttgaatca aatcctcata gctgataatt tgttctttaa
    12421 gggaactggc ggtttcaagt atcatctgcg tgatctcaaa agatgcaggt aattcgctga
    12481 ttctttctgc gacaggacca atggcgacag aaaaattatt tttttgtccc ttttctaatt
    12541 catggaccaa cgtttgggct acctgataac tggtctcgat cacattttct tcaagagaat
    12601 caactattaa aaatttgatg aatcgagagg aaacagcaga gaagatcact tgttgattct
    12661 ccctaaataa aaacttcaaa taatcactga gatgagcgta atcttcaaag tctgtactga
    12721 cttggtttgc tgctaataat acggtcattt ttttccctgc taaagagcga ttgaaagatt
    12781 cagcaagttt caatgtttca ctgatcgtaa gtgagccttt gaacaaaccg ttcaagaaat
    12841 gatttttttt caattcgaaa acaagatcag aagaagtgtg cgtttctttt tgctgcaaat
    12901 ctaaagcagt tactgctttt tctattgctt gtttcaattc gctactttta atcggtttaa
    12961 gcagataatc atctgcctgt acctggattg ctcctttcat ataatcgaaa tcgtcgaatc
    13021 cactaataaa tatgagacga gtccaaggaa gtagtttcct tgcttctttt gaaaaagtca
    13081 acccgtccat gaaaggcatt tggatatcag tcagaatgat gtcgggctgt aagtcgataa
    13141 ttgaagacag tgccatctca ccatctccag cttcgccgac ataagtgatt ggataataag
    13201 aaccaaggac agttatttgt tcccgcaagt tattgcgaat gaggtattcg tcttcgatga
    13261 taaaaacttt atacatgttt gtttcctcca attgttttgg gagatagagg gatcatcagt
    13321 gtgacagttg ttccttctcg gtatttgctg tcaatcgtga taggtttttg atcatttccg
    13381 taataaagaa ggagacgctt gtttacgttg taaagtccgt agccgatact gaaatctgaa
    13441 tcgatccctt tggctaactc tttacgtatt tctgccagtt tttctgcagg gatgccaatc
    13501 ccgttgtcta taactttgaa ttggatcatc tcatcaattt tgcatgtggt aatacgaata
    13561 aatcctttgt gacggacgta cttcgttcca tggtatacag cattttcaat caatggctgc
    13621 aagatcattt ttaaaataga aacaggaaaa agtgtttctg gtatatcgat cttatagtca
    13681 agcatatggc cgtatcttat ttttaagatg actagataat cattgatatg gctaatttct
    13741 ttttcaagag gaatccagtc ttgtcctttg cttaaagacg tacgaaaaaa gccggaaagt
    13801 gcatgggtca tagtcagagc ttcttcaaag cagtcttgtt cgatcaaaga aataatggca
    13861 tccaaactgt tataaataaa atggggagta atctgagctt gcaatacacg aacttcactt
    13921 tgtgctaaat ggtattgttt caaagcgttc tcccgtaaag actggtttag atcttccgcc
    13981 attttattca tgctagcggt aagtgtttgt aattccagtg tttccggcag ggttaaacga
    14041 aagccaaggt tccctgaaga aagttgttct gacatctcga tcagctgatt gatcggttct
    14101 tggacctttc tctctaaaaa gcgacgattc tttttcgcat agaaaaaaat ggtactaaga
    14161 actccaagtt ccactattgt taatagaatg agcgagcgga caagtgtcgt attttttttg
    14221 cttgctaagt cgatctccac acgaacaaaa tcttgtaaga tatctgacag cagttgagtg
    14281 acagaatcta cctgattgat gatctcttca ttggtatcca taaaatcttt tgccaagata
    14341 ttattgatca gctcgttttg ataatcttcc agtgtatcga tcgtacgtag cgatacatct
    14401 aacgtactaa tttctttaag tgtatttgta ttatttttga tctctcgaat atcattccta
    14461 agttcttcta ggatattttc ctcattgaac tcatctacgg ttacttggcc agaaatcaag
    14521 tcccacatac tttccaaaac tttttgatca accttcaaag caattgcatc tgctttttgg
    14581 atatttgcga tcgtctgttg ataaatcaaa agctgttgcg aatataacag tatgctcagt
    14641 agcaaaggga taacagcaaa tagaagcatg gctttgtttg cttgggcaaa aatctgtttt
    14701 atgcttaaat tttttgtcat gatacttctc cagtcaataa tttctggttg ggatgttagc
    14761 tatattctgc tgggaaaaga cagtctcgga aataaaaata tctttaggta atgtttttcc
    14821 tgtttgaata tttccaaaat aacgagtaac ggtattggct acataccagc cgacatcagg
    14881 tttacactcg actacacaat tgacgattcc tgagcgtagc ttctcgatca tatcttcttg
    14941 tccatcaata gttacaatga tcaaatcttc tccaggtttg attgatgttt cttttatcgc
    15001 agctaaagca ccgtgagtca tttcatcact atggctgtat aatacatcga tttcggataa
    15061 atcatttgtt tctaaatatc gtttcatctg gtcttttcct ttcatccgaa taaaatcacc
    15121 gacaattcgg tgaacaatag tcatcggagg tttatggtcg atggttccat ctttttttag
    15181 ggttggttta cgattgattg attccaaaaa tccttcggag cgtagcttgg tcggtgtgga
    15241 gttctctgaa ccagcaagtt ctaggattct gatttcctgt ttctttgaat ttgtgaagtg
    15301 attgctgaca aataaacccg cccgatttcc ttctgctttg aaactggggc caatgtgggt
    15361 gacgaaaagc tcgggatcat tcgtttgaat atgtctgtcg acaagtatga cagggatccc
    15421 tgctcgcttt gcttctttta atacagagtc ccacccggat tcttgcaaag gagtaaaaat
    15481 gatcatatcc actttatagg caatgaacgt ccgtatatct tggatttgcc gttcctgatt
    15541 catgtagcca tttcggtaga gaacttggta atcttctttt tcaagcgcag tgataattga
    15601 ttcagtatgc tttttccgcc agctactctc cgttcctgat tgcgaaaaac caacgactag
    15661 tgggtcaggt gcttcctttg tattaggtgt acaccccatc atttggtaag cgattacaac
    15721 aagggctaaa aaaaataaaa cacgtttcac tttaaatcac tccatctgga tttgttagta
    15781 ctatcttatc agataaaagg gaaaatcaaa gtcaaaagga atcaatcgaa aaaaatccaa
    15841 gaaacttaaa aaaatccaag acaaaaaaag tacacctaaa aaatttaaag taaatcccat
    15901 aaaaaaatca atgttaacgc tttctttatt agctatactc ggtgtatcaa ttgaaatggg
    15961 ggataaaaaa tgaaaaacaa atttagaaag attgttggga ctatcgctat tttgaccgca
    16021 agcattctat taagtgcgtg tggcaattca ggatctgcag atgatagtac ggggtatgta
    16081 ggaatcgcta tgccgaccaa atcagcagaa agatggatcg ctgatgggaa caacatggtc
    16141 tcggaattag aaaaactggg ttataaaaca gatcttcaat atggagaaga taaagtagaa
    16201 aatcaagtag cacaaataga aaatatgatt acaaaagggg tagatacact tgtgattgct
    16261 tctatcgatg gttcggcttt aactgatgtg ttagctaaag caaaagaagc agatatcaag
    16321 gtgatcgcct atgatcgttt actgatgaat tcagaaaatg tcgattatta cgcgactttt
    16381 gataattttg gagtaggtgt atcgcaagca gcttatattg aagagcactt aggattgaaa
    16441 gaaggaaaag gaccattcac gattgaatta tttggtggct cgcctgacga caacaacgca
    16501 ctaatcaatt acaacggagt gatgtctgtt ttacaaccat atatggacaa cggtcagttg
    16561 gtcgtgccat ctggacagac gagtttcagt caaatcgcta cgcttcgctg ggatggttct
    16621 acggcgcaag caaggatgga taatctgtta agcgcaaatt atactgacca aacattggat
    16681 gctgttttgt cgccatatga tccaataagt ttaggaatca tttcgtcatt aaaaggcgtg
    16741 gggtatggga gtgaaagtaa acctttacct gtgattactg gacaagatgc gacagttgct
    16801 ggcgttaaat cgatcattgc cggggaacaa acacaaacga tctttaaaga cacacgtatc
    16861 ttagcaaaaa atacgattga aatgatcaaa gcaatcagtg atggagaaga ggttccggtc
    16921 aatgatactg aaacttatga taatggggtg aaaactgtcc ctacgtattt agcaaataca
    16981 gtatctgtcg ataaagataa ttatcaagca gagctgatcg acaccgatta ttataaagaa
    17041 tccgatctga aaaattaaga ggaaccaaac aaggaactaa agagatctaa gtcagagaga
    17101 ggataagaat tatggcggat tgtattttaa aaatggcaga tatcaccaaa aaattttctg
    17161 gaatccgagc gttagattgc gtgaatctga tgattgaacg tggggaaatc catgcattgt
    17221 gcggagaaaa cggagcggga aaatcaacat tgatgaatgt cttgagcggc ttgtatccat
    17281 atggctccta tgacggggaa atcttttatg atggaaagct gtgtcaattt aaagatttga
    17341 aagatagtga agaaaaaggc atcgtcatca ttcatcaaga attagcacta agtccttatc
    17401 tttcaataaa agagaatatt tttctcggaa atgaacaagc agaaagaggc gtgattgatt
    17461 gggaactgac agaaaagaaa acatatgaac tgctgaataa agtcggtttg tctatcgacc
    17521 cgaatcttct agtatcccag attggcgtag ggcaacagca actagttgaa atagctaaag
    17581 cattatcaaa atccgtccgt ctgttgattt tggatgagcc taccgctgca ttgaatgaag
    17641 aagaaagcgc gaatttgctg agattgatcc gagagttgaa agagcaaggt gtaacctcca
    17701 tcattatttc acataagctg aatgaaatcg tggatatcgc agatcgaatc accattttac
    17761 gggatggaca gacgattgag acactagaaa atgaaatgat cagcgaagag catattattc
    17821 gcggaatggt gggcagagat ttagttgatc gttatcctga aagaaaaccg gatattggag
    17881 aagtttattt taaagtagaa gactggacgg tctatcaccc tcttgatcac gagcgaatca
    17941 taaacgacca catcaacttg catttgaaaa aaggagagat tgtaggaata gctggactga
    18001 tgggagcggg cagaactgaa ttcgctatga gtctatttgg acattcttat ggaagcaaga
    18061 tatccggacg tatattaaag gaaggggcag agatatcagt taagaccgtt ccttcagcca
    18121 ttgcaaacgg actcgcttat gtctcggagg accgaaaatc tttaggactg aatctgctga
    18181 tggatattcg ggaaaacgtg acgctgagca gtttggataa aataagtcaa aaaggagtat
    18241 tagataaaga aaaagaagta actgaggcag aaaatttccg gaaaaagatg cgtataaaaa
    18301 caaactccat ccatcaaatt gtcagtagtc ttagtggtgg gaatcaacaa aaagtcgttt
    18361 tatccaagtg gctgatgaca caacccgata ttcttttttt ggatgagcca acccgtggga
    18421 tagatgttgg ggcaaaatat gagatctaca cgattatcga agaaatggca gcaaatggca
    18481 aagctgtctg tcttatctct tctgaacttc ctgaaatatt agggatgtgt gatcgaatct
    18541 atacgatgaa cgaaggacgt attacaggag aagtctcgcg agaagatgca gatcaggaag
    18601 tcttgatgaa attaatgacg aaagaagagg tgggttaagt tggaacaggc aaaaaatctt
    18661 acggataaaa aagagaaaaa actaaatttg aaaagtagag cagctgatct ttttggtcgc
    18721 tacagcatgg tgatcatttt agcgggacta cttattgcgt ttcaattgat gacggatggt
    18781 attttctggc gtccattgaa tataactaac cttgttctgc aaaatagcca tatattagta
    18841 ctagctgcag ggatgttatt agttgtgctc ttaggtcatg tggatttgtc ggtagggtca
    18901 gtgatggcgt ttgttggtgc aattgcgggc atgatgatgg tcaatcgcca aatgaacccg
    18961 tggatgacag ttatcgcatg tcttgcagta ggcgggctga tcggcgcatg gcaaggtttt
    19021 tgggtagctt atgcagggat accggcgttt atcgtgactt tagcaggatt gctgatgttt
    19081 cgtggactga cacaagttgt tctaggaggc caatctctag caccttttcc agctgttttc
    19141 caaaaaatgt ctacgggtta tttaccagac ttaagcgaag gaagcagcct tcacttcttg
    19201 acattgattt taggaatgat catcacgatc gtgttagttg ttggtcaatg gcgaacaaga
    19261 aatcgtcgga aaaatcattt atttgaagtg gaatctccaa cagctttctt ggtaaaggcg
    19321 gtatttacag cagtcgttgt actaggaata acttatatct ttgcctctta tcaagggtat
    19381 ccgattattt tgatcattct tggtttgatc gttgcagcat atgggttttt gacaaataaa
    19441 acagtagcag gtcgacagat ttatgcgacg ggcggaaatc gaaaagcggc tgaactatca
    19501 gggatcaaaa caaagcgaat cacgttctgg gtattcgtca acatgggagt catggcagct
    19561 ttagctggat tagttttagc tgctcgattg aatgcggcaa cacctcaagc aggtacatcg
    19621 atggaactgg atgcaatggc ggcagtatat tttggtggtg cttcgacttc cggcggcatt
    19681 ggaacaatca tgggtgcgat tgtcggtggc ttggtcatgg gtgtattgaa caatggcatg
    19741 tcgattttag gcgtcggggt agactggcag caggcaatca aaggattgat cttgctttta
    19801 gccgttgtgc tagacttgta taataagaaa aaacgaacaa cgtaggagaa cgccggttat
    19861 tcagaaaaaa gactgtgaca agacatttgt cacagtcttt ttttcgctaa aagcgaacat
    19921 tcattgtttc gtttgtatag actaaaaata atatatgttt ttttaccatt cgtataaatt
    19981 ctctttttgc tcttgatttt tttgcttaat tgagttaaat tacatagggc gctaaaaaaa
    20041 gccttgatta aattaataat gttcgtgttt tgctggatgt gaacatcagg aggataatgt
    20101 aatgaaagta tttgattacg aagatattca attaattcct aataaatgta tcgtaaatag
    20161 ccgttctgaa tgtgatacaa cggtcacatt aggtaaacat acattcaaaa tgccagtagt
    20221 gcctgccaac atgcagacga ttattgatga aacaatcgca gaattcttag cggaaaatgg
    20281 ttatttctat atcatgcatc ggtttgatga agcagctcga attccgttta tcaaaaaaat
    20341 gaaaaagcgt ggattgatta cctcgatcag tgttggcgtc aagaaagagg aatattcctt
    20401 tatagagaag ttggcagaag aatcgctaaa tcctgattat atcactatcg acatcgcgca
    20461 tggacatgct aactcagtta ttgatatgat tcagcatatt aaaaaatatt tgcctgaaac
    20521 ttttgtgatt gccggtaatg ttggtacacc ggaagccgtc cgtgaattgg aaaatgcggg
    20581 cgcagatgca acaaaagtcg ggattggtcc aggaaaagta tgtattacaa aaatcaagac
    20641 aggctttggg actggaggct ggcaactggc agctcttaga tggtgtgcga aagcagctcg
    20701 caagccgatc atcgctgacg gtgggatcag aacacatggc gatattgcaa aatctgtccg
    20761 ttttggtgcg acaatggtca tgattggttc attgtttgcc ggtcacgagg aatctcctgg
    20821 cgaaacaaaa gtcgaaaatg gaatcgtgta taaagaatac tttggttctg cttcagaatt
    20881 ccaaaaaggc gaaaaacgaa atgttgaagg aaagaaaatc tggatccaac acaaaggatc
    20941 tttgaaagat acactagtgg aaatgcaaca agaccttcaa tcatctattt cttatgctgg
    21001 aggaagagat ctggaagcca ttcgaaaagt tgactatgtc atcgtgaaaa attcgatttt
    21061 taatggagac acaatctaaa aaataaataa aatattagga tgttgtgaaa aagttgtcct
    21121 gcattaagta ataagaacag ccaaacaaaa atagttcttt atatgttttg tttggctgga
    21181 attattatcg cagatacaag cttttgaaca tcattattca gaataaggga ctgtgataag
    21241 atttttgtca cagtccctta tgttttgcaa aaaaagtttt tcttttttct cgtaaattcg
    21301 gtaaaatcaa aagaaaaaat agacaataga aaagagaagc ttatgtggga aaaagtagag
    21361 aaaaaacaag gaccgattta tcgtcaaatt atggaacaga ttatgagaga aatcgaaaac
    21421 ggaaggatca atcctggaag tcaacttgaa tcagaacgaa aactagggca actttttggt
    21481 gtgaatcgtt ccaccgttgt ccatgcattg gaagagctta gggagcttgg ggtactaacg
    21541 agcaaacgtg gcagcggatg gtttgttaat cagactgaat gggggaaatt cgctgttcca
    21601 agaatcgatt ggcggcaaat gatctctcct cgttatgagc agacggactg gtatgagcaa
    21661 aaaataagag aagcaaagca gatccaaaaa acatcgtttc ttgatttata cgctagcgag
    21721 atgccagatg agcttttgcc gaattttgag tttccttctt attctcttga agaaatctta
    21781 gcggaagaaa aagaaatgga tcttttaggc tatactccgt tacgtaacaa aatcaaacgg
    21841 tatttggaaa gtaaatttga attggcattt tcccccaacc agcttcttgt gactggtggc
    21901 ggtcagcaag caatcttttt gattttacaa acgattcttt cagctggaga ggggatagct
    21961 gtagagtcac cttctttttt ttaccgatta cctcttttca aagcttcagg aacgcgttta
    22021 tttgggatac cgatggatga agaagggatc gacttagaaa aactgaaaga atcgatccat
    22081 aaaaataaat tgaaagcagt gcttatcaac ccgaattttc aaaaccctac aggaaaagtg
    22141 atgagtcaaa aacgacgaga aaagctagta gaattgtgtc gacagtatcg gcttccaatt
    22201 attgaagacg atgtatttac ggatctttca tttctaaacc aagaagaagt ccttcctata
    22261 cgaacgattg atccggataa tgtgttatac gtcggttcgt tatctagggt tttaggaaaa
    22321 acaacgaaaa tcggttgggt gataggacct gagactttta tctcgcaact agctcaagcg
    22381 caagaaatga tggagttttc gatgaatatc cttacacaaa tcacagtggc taatgtattt
    22441 aatgaagcaa ttgatttgaa aatgcaagat gtaagaaaaa agttgaaaga aaaaagccga
    22501 ctgataagcg cttggggaga ttcacaatcg tttttcaagc ttcattcaat tttaggtggt
    22561 tactatgcct ggattacttg ggatgggaaa aaactagacc ccgaactagc agaaaaagta
    22621 gtagatatgg gtcttggaat tgcaccaagt ctactttttg ggcaagatat aaatggaatc
    22681 agaatcaatt acagtaggct ggatgaaaac caaataccgt tgttttattc aaagatgaaa
    22741 attctagaaa agtggttaac agaataattt cacaaagtaa atagattaaa gaatataaca
    22801 gcttggattt aaatttcaag ctgtttcttt tttttcggaa aaagaatacg atataaagaa
    22861 actaagaaaa aaccattatt tgtacgtccg ttcacgatgt gtaaataaaa taaatgtttg
    22921 caacaaaact gtataacacc aacgttttta aatagaaaca gatggttgta agtttgatta
    22981 gaaaatagaa aaaatgcaga tgaaatataa aacgctttcc ttattgtgat tttattcact
    23041 aatgctgtta atatgcggat tggcataatt tcctttcatc gtgaaaattt gtgcttttag
    23101 cttgtatttc tcataaatcc atgataattt attaatgaag acggttaaat agtgatacag
    23161 ttttattcac tgtttcaatc gcagaatgaa gagattttct tatagatgag agaggaatgt
    23221 gtgacaaatg gcaaacaaaa aagcaccgat cgacttccaa gcactgctag atgaagtcaa
    23281 tgcagatttc ccagtatatc aagcacttga tcaagatgga aacgtagtta acaaagattt
    23341 agtacctgat ttatccgatg atgaactcgt tgaattaatg actcatatgg tatggtctcg
    23401 tgtattagac caacgttcaa cagcgctgaa ccgccaagga cgcctaggct tttttgcacc
    23461 aactgctgga caagaggcaa gtcagctggc tagtgcttac gcatttgata aagaagatgt
    23521 tcttcttcca ggttatcggg atgtacctca actagtaaaa catggtttac ctttatctca
    23581 agctttttta tggtctcgag gacatgctgc aggtaattct tatccggaag aattgaaagc
    23641 tctaccacca caaattatca tcggtgcaca atatgtacaa gcagccggtg ttgcattagg
    23701 tttgaagaaa cgaaacaaga aaaatgtcgt cttcacttat actggtgatg gcggttcatc
    23761 acaaggtgat ttttacgaag caatcaattt cgctggcgct taccatgcaa atgccgtatt
    23821 ttatatccaa aacaacgggt atgcgatctc tacacctcgt gaaaaacaaa ctgcagcaaa
    23881 aacacttgca caaaaagctg tcgcagctgg gattcctggt attcaagtcg atggaatgga
    23941 tccgcttgca gtatatactg tatctaaaat ggcacgggaa tgggcgatca gtggaaatgg
    24001 accagtccta atcgaaacac tgacttatcg ttatggacca catacactat ctggtgacga
    24061 tccaacccgc taccgtacaa aagacacaga tgacgattgg cagaaaaaag atccattgat
    24121 ccgcttccgt aaatatttga cggaaaaagg actttggtct gaagaaaaag aagaacaagt
    24181 catcgaagca actaaagaag aaatcaaagc agctattgct gaagccgaca aagtaccaaa
    24241 acaaaaggtt tcagatttct tgaaaaacat gttcgaagta tctccacaat caatcaaaga
    24301 acaaattgca atttatgaag cgaaggagtc gaaataatca tggcacaaaa aacaatgatc
    24361 caagcaatca cagatgcctt agcacttgaa ctagaaaatg acgagaatgt cgttgttttt
    24421 ggtgaagatg ttgggaaaaa cggaggagtt ttccgggcaa ctgaaggatt gcaggaaaag
    24481 ttcggagaag accgagtatt cgatactcct ttagctgaat ctggaatcgc aggattgagt
    24541 ttcggtcttg cgttagaagg atttcgtcca gttcctgaaa tccaattctt tggttttatt
    24601 ttcgaagcaa tggacgaagt agtagctcaa atggctcgta caagatatcg aatgagcggc
    24661 actagaaatc tacccatcac aattcgttcg ccatttggtg gcggtgttca tacaccagaa
    24721 ttgcattcgg ataatttaga aggtttgatc gctcagtctc ctggtattcg agtagtgatt
    24781 ccttccaacc cttatgatgc aaaaggacta ttgatttctt ctattagaag taacgatccg
    24841 gttgttttcc tagaacacat gaaactatat cgctcattcc gagaagaagt gccggatgaa
    24901 gcttacgaag ttcctttgga taaagcagca gttactcgtg agggaacaga tgtatctatt
    24961 atcacatacg gagcaatggt gcgtgaagca atcaaagcag cagacaatct tgcaaaagaa
    25021 aatatatctg ttgaaatcat tgatcttcgt acagttgcgc cattagatgt agaaacgatc
    25081 attcaatccg tggaaaaaac tggtcgcgta gttgttgtcc aagaagcaca acgacaagcg
    25141 ggcgttgccg cgcaagtagt ttctgagatc tcagaacgcg ctatcctttc attagaagcc
    25201 ccaatcggac gagtttctgc acctgataca gtcttcccat ttggacaagc agaaaatgtc
    25261 tggttgccaa atgcaaaaga tatcgaagac aaagtaaaag aaatcgcgga attttaagaa
    25321 aagaagggac gaaacaaagt catggcttat caatttaaat tgccggatat cggtgaagga
    25381 atcgcagaag gtgaaatcgt caaatggttc gtcaaaccag gagatacgat caatgaagat
    25441 gatacattac tagaagttca aaatgacaaa tcagtagaag aaatcccgtc acctgttaca
    25501 ggaacggtta aaaatgtgat tgttccagaa ggtaccgtag caaatgttgg ggatgtatta
    25561 gtagaaatcg atgcaccagg acacgaagac aatgaagggg acagtggtgt agccgcagaa
    25621 tcccaaactc cagctaaacc ggctgctgaa cccactgttg atacagaatc agctggatcg
    25681 tcaagcgaag gagtcttcca atttaagtta ccggatatcg gtgaaggaat cgcagaaggt
    25741 gaaatcgtca aatggttcgt caaaccagga gatacgatca atgaagatga tacattacta
    25801 gaagttcaaa atgacaaatc agtagaagaa attccgtcac ctgtcacagg gacagttaaa
    25861 aacgtgattg ttccagaagg cactgtagca aatgttgggg atgtattagt agaaatcgat
    25921 gctcctggac acaatagtgc accgtcaact agtgcgccat cagctgaagc accaaaagaa
    25981 aaagtggaaa catcaggttc agcaagtgtc gttgaagctg ccgatccaaa taaacgtgta
    26041 ttggctatgc catctgttcg tcaatttgcc cgtgaaaaag atgtagatat ctcacaagta
    26101 actgcaactg gaaaaggtgg cagagtaaca aaagaggaca tcgaaaactt cttggcaggt
    26161 ggtccaagca gtgcaccagc gaaatcagaa gcgccagaag cggcagcacc gaaagaagca
    26221 gctcctgcag cagaaagcaa accagctgca ccagcaaaac cattcaagtc caacttagga
    26281 gacttggaag aacgtgtagc aatgacgcca acacgtaaag ctatcgctaa agcaatggtc
    26341 aacagtaagc atacagctcc acacgtgaca ttgcatgatg aagtagaagt gtctaaacta
    26401 tgggataatc ggaaacgatt taaagaagtt gctgctgcaa atggtacgaa acttactttc
    26461 ttgccatatg tcgtgaaagc tttaacagcg actgttaaga aatacccagt attgaatgca
    26521 tctatcgacg atgcaaacca agaaatcgtt tataaacatt actacaatat cggtattgca
    26581 actgatacgg atcacggact atatgtacca aatgtgaaag atgcagaccg caaaggaatg
    26641 tttgctattg cagacgaaat caatgagaaa gcaaaattag ctcatgacgg caaactatct
    26701 gcagaagata tgcgcaatgg aacaattacg atcagcaata tcggatctgt aggtggcggt
    26761 tggtttacac cagtcatcaa ctatccagaa gtagctattt taggtgtagg aacgattgca
    26821 caacaaccaa tcgtaaatgc tgaaggcgaa atcgttgtcg gtcgtgtgat gaaactgtca
    26881 ttaagtttcg atcaccgtat cgtagatgga gcaactgcgc aacaagcaat gaataatatc
    26941 aaacgtcttt tagctgatcc agagctatta atgatggaag gatgataaac aaatggtagt
    27001 tggagatttt gctgtagaat tagatacagt tgtaattggt gcgggacctg gtggctatgt
    27061 agctgccatc cgcgctgctg aaatgggaca aaaagtagca atcattgaaa gagagtatat
    27121 tggcggtgtt tgtttgaatg tcggctgtat tccttcaaaa gcactgatag ctgcaggaca
    27181 ccattatcaa gagtcactag attctgaaat gtttggagta actagtgaaa acgtcaaact
    27241 agattttgca aaaacacaag aatggaaaga aaacaaagtt gtccatacgt tgacttctgg
    27301 tgttggtttc ctattaaaaa aacataaggt tgaaacaatc gaaggagaag cgttcttcgt
    27361 agatgatcac acactacgcg tcattcatcc agattcagct caaacttatt cgttcaataa
    27421 cgcaatcatc gcaacaggtt cccgtccaat cgagattcca ggatttaaat tcggaggacg
    27481 tgtgttagat tctactggcg gattagcatt gaaagaagta cctaagaaat ttgtgatcat
    27541 cggtggcggt gtgattggtg ccgaattggg cggagcgtac gcaaacttag gagcagaagt
    27601 aacgattctt gaaggctcac cacaaatttt accaacttac gaaaaagatc tagtaaaatt
    27661 agtagaagat gatttcaaga aaaaaggcgt aacagtcgta acgaatgcaa tggcgaaaga
    27721 agcagtcgat aacggtgaca gcgtgacagt gaaatatgca gtggacggga aagaagaatc
    27781 cgttactgct gattatgtga tggtcactgt aggtcgtcgt ccgaatacag atgatatggg
    27841 cttagaacaa gcgggtgtcg aagtaggaga acgaggattg atcacggtgg ataaacaagg
    27901 acgtacgaac gtacctaaca tctatgccat cggtgatatc gttccagggg cggcattagc
    27961 acacaaagcc agttatgaag caaaaatcgc tgctgaagca atctctggca aaaaagtagc
    28021 tgtagattat aaagcaatgc cggcagtagc cttcactgat cctgaattgg cttctgtagg
    28081 tatgacgatc aaagaagcaa aagatgctgg tatcgaagca aaagcatata aattcccatt
    28141 ttcagggaac ggtcgggcat tatcgcttgg taaaacagaa ggattcatcc gtctagttac
    28201 gacgatcgaa gataacgtgc ttattggcgc gcaaatcggt ggagtcggcg caagtgatat
    28261 ggtctctgaa ttagctttag caatcgaatc aggaatgaat gctgaagata tcgccttgac
    28321 gattcatcct catccatctc ttggcgaaat cgtcatggat gcttcggaat tagcattagg
    28381 tttaccaatc catatttgat ttgaataata caggcgaaac gcaactgaaa aatcagttgc
    28441 gttttgtttt ttagaattat caataatatt attatgtaaa cttaaaaata tgacaacttc
    28501 ttggtttatt accacttcct atgctacact gaagaggaat atgaaatagg agagttgaag
    28561 atgcaagaat atcagtatcc acttgattta gattggacaa cagacgaaat ggtcattgta
    28621 atgaagatgt gggaagatct ggaacgtgcg aatgaaaaag ggataaacaa tgaagctttt
    28681 ttgaagactt atcagcagtt taaaactgtt gtcaaatcca ttggtgagga aaaacgattg
    28741 ggacgggaat ttgaaaaagc ttccggttat tctttatatc gtacagtgca gcaagcaaaa
    28801 aaaaatccaa acaaaacttt gagaatgaac gggtgagata aatggaacag atgattgatc
    28861 atatcaagtc ctggcttgaa gaagctggtg agaaaatcaa atcttctcaa caaacattaa
    28921 caatctcgca aaaatcaaat cgaacggatc tagtaacaaa tgtcgatcga aacatccaga
    28981 attttctaat cgaaaaaatc cattcctttg atccagaggc gaaaatattg gcagaagaag
    29041 aagggtgtaa tcaattatcg gatctcgatg gaagagtctt tatcatcgat cctattgatg
    29101 gcaccttgaa ttttgtgatt gaaggggaaa atttttgtat tatgctcgct gtttatgaat
    29161 ccggcgttgg aaagcttggt ttcatttatg acgtgatgag aaatgaactt ttttggggtg
    29221 gaaaaggaat aggcgtgtat aaaaatgatg agccattgcc tagaccagca aataaatcct
    29281 tatcggaagg cttacttggt gtgaatagtt atcttttcgg tcataataaa tatggaatcc
    29341 gagaaattgc ggaaagcagc atggggacac gtatgtacgg atgcgctggt cttgaactag
    29401 tggcaatctt gaaaggaaac cacattgctt atatttcaaa ccttagccct tgggattatg
    29461 cagcgggaaa tgtcttattg gaagagtttg gtatggtaac aagcggtctt tttggtactc
    29521 ctttgacatt tgaaaaaagg gaatactatt tagcagggac ttcttgtgca tatgcagaaa
    29581 tcgcagacct tttgaaaaaa gaaggctgaa aaaaaggtag aaatcattca caaaaatgat
    29641 aaaaacgagc aaaagattaa ttttctcgaa aaaatgaaaa cattttacta tatttcatga
    29701 aaaaagtctg ctataattag cagtcgagta aaatttgccc tgtcataaag aaccaataaa
    29761 aaaggagtta gttacattga attatagaaa cgatatccgt aacgtcgcaa ttattgccca
    29821 cgttgaccac ggaaaaacaa cattagttga tgaactatta aaacaatcag atacattaga
    29881 cgcacatacg caattgcaag aacgtgcgat ggactcaaat gcgctagaaa aagaacgtgg
    29941 tatcacgatt ttagccaaaa acacagctgt agactataaa ggtattcgcg taaacatcat
    30001 ggatactcca ggacacgcgg acttcggtgg cgaagtagaa cggatcatga aaatggttga
    30061 cggcgttgtg ttggtcgtag atgcgtatga aggaacaatg cctcaaacac gttttgtatt
    30121 gaaaaaagca ctggaacaac atatcacacc aatcgttgtc gtaaacaaga ttgacaaacc
    30181 ttctgctcgt cctgagcatg tcgtagatga agttcttgaa ctattcatcg aattaggagc
    30241 agatgatgat cagttagact ttcctgtgat ttatgcatct gcactaaatg gtacgtcaag
    30301 cttgtcagat gatccagcag atcaagaacc aaccatggca cctatttttg atacaattat
    30361 tgaaaaaatc cctgctcctg tcgataacag cgacgaacca ttacaattcc aagtttcatt
    30421 acttgactac aacgattatg taggtcgtat cggaatcgga cgtgtattta gaggaacaat
    30481 caaagtagga gaccaagtag cattaattaa attagacgga acagttaaga aattccgtgt
    30541 aacgaaatta tttggtttct ttggactaaa acgtctagag attcaagaag caaaagctgg
    30601 agacttgatt gctgtctcag gtatggaaga tatctttgtc ggtgaaacag ttactcctgt
    30661 ggatcatcaa gatgcgttac ctatccttca cattgacgaa ccaacattgc aaatgacttt
    30721 cttagttaat aattcaccat ttgccggtcg agaaggtaaa ttcgtaaccg ctcgtaagat
    30781 tgaagaacgt ttgatggcag aacttcaaac agatgtatcc ttacgagttg aaccaacaaa
    30841 ctctccagat gcatggacag tttctggtcg tggagaattg catttgtcta tcttgattga
    30901 aaacatgcgc cgtgagggat acgaattgca agtatctcgt ccagaagtta ttgaaaaaga
    30961 aatcgacggt gtaaaatgcg aaccgtttga acgcgtgcaa atcgatacac cagaagaata
    31021 tatgggtagt gttatcgagt ccttgagctt acgtaaaggt gaaatgcaag atatggtcca
    31081 tacaggaaac ggacaaatcc gtttgacatt cttaacacct gcccgcggtt tgattggtta
    31141 ttcaactgaa ttcctttcaa tgacacgtgg ttacggaatc atgaaccata cttttgacca
    31201 atatctgcca atgcttcctg gtcaaattgg cggacgtcac caaggggcgc ttgtttcgat
    31261 cgatacagga aaagcaacga cttattctat catgagtatc gaagaacgcg gtacagtctt
    31321 cgtagaacca ggtacagaag tatatgaagg aatgattatc ggggaaaaca gccgtgataa
    31381 tgatttgact gtcaacatca cgaaagcaaa acaaatgaca aacgtacggt ctgctactaa
    31441 agaccaaaca tctgtcatca aaaaaccaaa acaattgacg ttggaagaat ctttggaatt
    31501 cttgaatgat gatgaatatt gcgaagtaac accagaaagc attcgcttga gaaaacaaat
    31561 tttagagaaa aatgctcgtg aaaaagcatc taaaaagaaa aaataatctg taaaaggatg
    31621 aagagagaaa ccagcttgtt ataaaaaata gctggtttct ttttttgtcc aactcttttc
    31681 tgtggagaag tcatctttgt caatggacat aaattcagaa aatacgccga aagacgttta
    31741 aaagactttt aaaaaactta tttctagaga gtttttgttt cataataaga taatgtttca
    31801 cgaaaggaga tcaacttgtc cttcgaagaa aatcgaagta aaatggcaag agaaaggagc
    31861 gggaagatga acgacttatt aaaacaatac tttggctatg atgagtttag acctggtcaa
    31921 aaagaaatta tccagaaagt cattgatcag gaaaatgtat taggaatcat gcctaccgga
    31981 agtgggaaat caatctgtta ccagcttcca gctttactat tagatgggct tactgtggtt
    32041 gtgtcccctt taatctcttt gatgaaggat caggtggacg cggcgaatca attaggtata
    32101 cccgccactt ttatcaatag ctcgttagat ggttacgaaa cagctagacg cttccaagaa
    32161 atcgatagac agcagtaccg tttactttat atcgctcctg aacgttttat catgccggat
    32221 tttatccaag caatgaagcg atggaacgtc cgtatgatcg ctattgacga ggcacattgt
    32281 atctctcagt gggggcatga tttccgccca agttatttac agatggcgaa ccagctagat
    32341 caactgccaa atcgtcctgt aattgttgct ttgacagcta cagcgactgt gcaagtagct
    32401 gctgacataa aaagactttt aaaaattcca gaaaacaacc atattcagac tggttttgaa
    32461 cgagaaaatc tacgatttca agtaattaaa gatcaaaaaa aagaacaata tctaatcgaa
    32521 tatttaaaga tcaacaaaaa tcaatctggt atcatttatg cagcaacgag aaaagaagta
    32581 gaccgtctct atcatttgct taaaaaattc gatttttccg tgggtagata tcatggtggt
    32641 ctaaatgaga atgagcgaac agaaatgcaa gaagcctttt tatacgatcg cttgcagctg
    32701 attgtagcga caaatgcatt tggtatgggt ataaataaaa gcaatgtccg ttttgttatc
    32761 cattatcaaa ttcctggctc tctagaagca tactatcagg aagctggtcg ggcgggaaga
    32821 gatggtcttt ccagtgaagc catcctgctt ttctctcctc aagatatcca agtccaaaag
    32881 ttttttatcc agcagtccca aagagaagaa gggcaaaagc aaaaagaata tgaaaaatta
    32941 aaagcgatga cagaatacgt gtatattgag tcctgtcttc agcaatacat cctaaactat
    33001 tttggcgaga caagcagtcc gtgcaaccgt tgtggtaact gtttagatga cagagaaata
    33061 gtagaagtaa cgacagaagc acagatggtt ctttcttgct taaaacgtat gggtgagaac
    33121 tatggtaaac aaatgctgat gaaagtctta gcaggatcga aagaacaaaa gctgcaagct
    33181 ttaggttttg gacatttatc tacctatgga ctgatgaaaa accaatcgca aaaagaaacg
    33241 atgcagttaa ttgaatattt gatatcgaat ggctatcttc tgaccatcaa tggtgagtat
    33301 cctgttttga aagtaacaga aagagggata caagtattga aaggacaaga atctgtttat
    33361 cgaaaggaac ccaagaaagt ccagcagcta tcggatgaag aaaccgatac actatttgaa
    33421 gtgctgcggg aactgcgaac ggatctagca tcagaagcag gcgttccccc gtatgtcgta
    33481 ttttcagatt ccacattgaa agaaatgagc cgaatacgtc catcaagcag attggagatg
    33541 cttcagataa aaggagttgg ccaaagcaag cttgataaat atggcgaagc ctttttatct
    33601 cggataaaaa atgcggactc taacgttctg gataagtaga aagaacgaat acgtaaaaat
    33661 gaataaaaac aactggttaa atctgttttt tttgctcctt atgaaaatca aatatgttat
    33721 aattaaggaa ttagaatggg aggtaagcac agatggattc tttgtcgaaa aaacttgcga
    33781 tccaagtatt aaatgatgaa gcagaacgga tcaaacgatt aatccgaaat caaaacaaca
    33841 gtctctgtat ctcacaatgc aaagccttcg aagaagtggt agatacacag atgtacggct
    33901 tttcccggca agtcggtttt gctgtccgta taggagtaat cggaaagaac gagggccagc
    33961 tgatgttaag tgagctagaa cgagaattga atcagttata tagtgaggtt taccaagaaa
    34021 tttatgataa aaaagaagtt ggcaaggagg aatagacttg cctaagaaag tgaaaaaaag
    34081 gcatctatta gactatagca tcttgattcc ctatttaatt ttatgtgtat tgggattgat
    34141 catggtatat agttctacgt cgtatctatt attagaaaac ggacaaaatc cgtccgcatc
    34201 agtcattaac cagagtattt tttgggtgct tagcttgatt gctatcgcac tactttataa
    34261 aatgaaaaca gatgttttga aaaaccagcg tttgatcatg gcagccatcg cagttttgac
    34321 gattttgctg ctgattgttg tgttttttgg taaggagatc aatggggcga aaggttggct
    34381 gcaaattgca ggattctcga tccaacctgc cgaataccta aaaatcattt ctatctggta
    34441 cctgtctctg actttatcta aaagacaaaa cagtgtacaa aaagattttc ttgggactgt
    34501 gaaacgtcca cttgcaatgg ttatcggact tactgcatta gtcgctattc ttcccgattt
    34561 tggtaatgcg gcagttatct ttttgattat tttggttctg cttttagcca gcggagtcaa
    34621 ttatgtgtat actttgattg taggagtagg aggcttttgt ctaagtactt ttacgatctg
    34681 gctgatcaat atcacaaacg gaaagatctt acccggacgt ttacagtata tctataatcg
    34741 atttgctatt taccaaaatc ctttctcaga cgaattaaat aaagggcatc aactagtcaa
    34801 cggctactat gccatgttca acggaggact atttggcagg ggattaggta acagtatcca
    34861 gaaaaaagga tttttacaag aagcacaaac cgattttatt tatgcaatcg tagtggaaga
    34921 actgggagtg attatgggga ttttgatatt agcgttgcta ttctttatga ttgtgcgcat
    34981 tgtccttgta ggtatccgtt caaaagatcc gttcaattcg cttttgtgca ttgggatcgg
    35041 cgcaatgttt ttgatccaag tatttgtcaa tcttggagga attactggcg ttattccttt
    35101 gacagggatc acgttcccat ttttaagtca aggaggctcc agtttgctga tgctttcgat
    35161 ttgtgtcggc tttgtcctca acatcagtgc ggatgaaaaa cgcaagagct taggtttata
    35221 ataaaaaaag atgtaggagt ggttcgatga aaaaagtttt agttgctaac aggggtgaaa
    35281 tcgctgtacg tgtatttcgt gcttgtacag aattaggaat taaaactgtt ggaatctatg
    35341 cagaagaaga tgaatattcc gtacaccgtt tcaaagcgga tgaagcatat ttagtaggac
    35401 aaggaaaaaa accgattgat gcgtatctag atattgaagg gatcatttct atcgcgaaag
    35461 aatgcggagc tgacgctatt catccgggtt acggtctttt gtcggaaaac ttgaattttg
    35521 cgcaacggtg cgaagaagaa ggcatcattt ttgttggacc caaactgcat catttagata
    35581 tttttggaga taaaatcaaa gcaaaagctg cagctatcga agcggggatt gcttcgattc
    35641 caggcacaga tggaccaatc gcttctatag acgatgcctt ggagtttgcg aaacaatacg
    35701 gttatccgat tatgatcaag gcagctctag gcggcggcgg acgcggcatg cgtgtagctc
    35761 acgatgaaaa gagtgcaaga gagggctacg aacgtgcgaa aagcgaagca aaagcagcct
    35821 ttggtagtga tgaagtgtat gttgaaaaat acatcgctaa tcctaagcat atcgaagtac
    35881 agattctcgg ggatacgcat ggaaacgtca tccatctttt tgaaagagat tgttctgttc
    35941 agcgccgtca ccaaaaagta gtagaagtag cgccttgtgt ctctatgaat gaacagcaac
    36001 gtcaaaaaat ctgccaggca gctgtccaat tgatgaaata tgtcgggtat gtcaacgcag
    36061 gtacagtaga atttcttgtt gaaggagatg atttttactt tatcgaagtc aaccctcgcg
    36121 tccaagtgga acatacgatc acagaaatga ttacagatat tgatatcgta acaacgcaac
    36181 tgttgattgc tcaaggtttg gatctgcata aagaaatcgg attgcctcag caagaaggaa
    36241 ttaaattaaa tggttcagcc attcaatgcc gaatcactac agaagacccg ttgaataact
    36301 ttttaccaga cacagggaaa atcgatacgt atcgttcacc tggtggtttt ggcgtacgtc
    36361 tggatgtcgg aaatgcttac gcgggctatg tagtgacacc gtattttgat tcattgctag
    36421 taaaagtatg tacgcatggt gctacctttg aaacagccat tcagaaaatg gaacgttgct
    36481 tgaaagaatt tagaatccgt ggagtgaaaa caaacattcc atttatgctc aatgtcatca
    36541 cacatcctga attccaatca ggaaatgcaa aaacaacctt cattgatagt acagcaacat
    36601 tatttgaatt tcctcgacta cgagaccgcg gaaacaaaac gatgaaatat atcggtgaaa
    36661 ttactgtgaa tggttttcca ggtatcgaaa gtggcgaaaa accattttat gaagaaccac
    36721 gtatgcctaa agatctaatc acaagaactg attacgtaac ggctaagaat gtattagatg
    36781 cgaagggtgc cgatgctttg gtcgaatgga tcaaaggaca ggaaaatttg ttgttgacgg
    36841 atacgacatt tagagacgcc catcaaagtc tgctagcaac tcgtgttcgg acaaaggatt
    36901 tcaagcagat tgcacgtttg actggagaag gtcttcctga actcttttca agtgagatgt
    36961 gggggggagc aacatttgat gtggcttacc gctttttgaa tgaagatcct tggcaacggt
    37021 tgagaaaaat tcgttcttta atgcctaata cgttgctgca aatgcttttc agaggttcaa
    37081 atgccgttgg gtattctaat tatcctgaca atgtattggt ggaatttgtc aaagaagcag
    37141 cagcgcaagg aatcgatgta tttcgaatct ttgatagttt gaactggact ccacaaatgg
    37201 aaaaaagtat ccaagctgta cgggatactg gtaaaatcgc agaggcagct atttgctata
    37261 ctggcgatat caacgatcca agtcgggcaa aatacaatgt tcagtattat aaagacatgg
    37321 caaaggaact agaacaactg ggtgcgcata tcattgcaat caaagatatg gctgggctgc
    37381 ttaaaccgca ggcagcttat cgtttgatta gtgaattgaa agaaacgaca gatctgccaa
    37441 tccatctgca tactcatgat accagcggga atggaatcat cacttattct gctgcttcaa
    37501 aagcaggagt agacatcgtt gacgtggcaa tgagtgcaat gagtgggaat actagtcagc
    37561 ctagcatgag cagcttgtat tatgcactgg tcaatggtcc acggctgcca gaaatcacga
    37621 ttgaaaatgc acagaaatta aaccattatt gggaagatgt gcgcatgtat tacaaaccgt
    37681 ttgaaaacgg cttgaatgct cctgaaacag aagtatatat gcatgaaatg ccaggaggac
    37741 agtattcgaa tctacagcaa caggcaaaag ctgtcggatt aggtcatcgc tgggatgaaa
    37801 tcaaacaaat gtatcatact gtcaacttga tgtttggcga tatcgttaaa gtaactccat
    37861 catctaaagt agttggagat atggcactat ttatggtcca aaatgatctt acagaagaag
    37921 atatttatga aaaaggcgaa acactaagtt tccctgaatc tgttgtgact ttcttccaag
    37981 gagaactagg gcaacccgtt ggcggatttc ctaaaaaatt gcaaaagatt attcttaaag
    38041 gcagacctgc attgaatgaa cgtccaggtc ttttggctga atcagtcgac ttcaacgaag
    38101 taaaaaaaga attggcagaa aaaattggct atgaaccaaa acaagacgaa gtattaagct
    38161 atttgatgta tccgcaagtc tttttggact atcaaaaagc atataatcaa tttggcgatg
    38221 ttacattact ggacacacca acatttttcc aaggtatacg tttgggtgaa acaatcaatg
    38281 tacaaatcga acgcggaaaa acgcttatca ttcgtttaga tgaaatcgga gaacccgata
    38341 tcgaagggaa tcgcgtactg ttcttcaatt tgaatggaca aagacgtgaa atcactatca
    38401 aagataattc gatcatcagt acggtccaaa cccgattgaa agctgaaccg acaaaccgag
    38461 aacaaattgg agcaacgatg tctggttctg ttttggatgt attagtgaaa aaaggcgata
    38521 acgttaaaaa aggtgatacg ttgatgatta ctgaagcgat gaaaatggaa acggccatcg
    38581 aagcacgttt tgacggagaa gtcgcacatg tatatgtgtc ttcaggagac actatttcgt
    38641 ctggtgacct tttgattgaa gtgactgaga aataataagc gaaaggtggg gaaacatgaa
    38701 aagactgggt ttgttttggc tgattctgct attagttatt gtggcattct acatggaacc
    38761 agtcttgttt ccgccaaaac ttgaagtgaa ggaaaactct gatcaacaaa tatcaaacca
    38821 aatgacaacg tggaaatacc aggagcttaa agcaactggt ttttctactt atatcggaaa
    38881 accgatcgat cagctggaaa aggattttgg ccaagcctat gatcgattaa ctagcggatt
    38941 tggttttgaa acaagatatt atgaaaataa agctagtcat ctcacatttg aagcgaacat
    39001 ccaagacagc agagtcacaa ctgttaaagt actgcaaaca gggcctgctg atatcgcgcc
    39061 gttttattta gggatgacga tgcaagatct tacgaaaatc actactatct atactaattt
    39121 cacttttgag taccatgata cagaagttgg aatcgaacta atggaagagg atatgaatta
    39181 tcgtccgcta attgcttttg ataacgacac ttttgctatt ttattttttg atcaaacaac
    39241 aaacggccta ttttcagttg tgtatttaga taaagatagt cttttgaaac tattgccata
    39301 tcaagtgttt ggtgaaggcc ttccacatta tcaagcagat aaatcggctg attgggaatc
    39361 aatcaatcgc gttaaagaac gaaaaagtac gactttatta aatatgctta gaagagaaga
    39421 cgaacttccc atatacaatc aaacacttgc ctttcaaaac cacagtcagc tgctactaca
    39481 tgattttttg acaaggcctg aggaaatatt gtcagaggaa cgtatggctg attggcaaaa
    39541 atcgctaggc agtgctcaaa cgacagtgaa attctcactg acgaatgatg aattggagaa
    39601 gttaatcagt aaacaaaaat tagaaaatac tagtgggcta tttattcatc cggcgattga
    39661 cgctactttt tcgtttttat attggtacag cgatccttac aaccatgacc gtttcatgga
    39721 cccgggaacg gattctgtag gcattgcttt ttctaaagaa aatatgttag tcttattgca
    39781 agaagaaaac ggagaaagta gtgatagcag tgatcgttaa cgaagagctg tttcaactgg
    39841 aggatcaatg cctccaagtc gctgaaatga taaaaaagag taaaacgatg gcttcttatc
    39901 ttgaacataa acagtcaatg gaagaatctg caaaagtttg ccagttgaaa gaagcgttct
    39961 tgtctaagaa agaagcattt gaaaatgtag cggcatatgg tgagtatgca cctgattatc
    40021 gtgaaaaaaa acgagctgtt cgaaaagcaa aaagacagct tgatatggat gagcatgttg
    40081 cagctttccg atatagtgaa acacagctgc aaagtctgtt ggatcaaatt gtccaagtac
    40141 ttgccgaaga agtttctaat gaaatcaaag tagatgcagg tagcccgttt tttgaaacga
    40201 aaaaacactt tggatgcgga ggtaattgtc atgcaattag acaatagtga atttgaaata
    40261 acaaaacgac gcgggctgat cgtatgggtc tacagcttaa aacaattaaa gaatctgaaa
    40321 aagttcggct tgttgcatta tgtctcaaga agaatgaaat atgtcgtgct ttacttaaat
    40381 gaagagacat tggaagaaac agaagaacga atccgtaaat tacattttgt tcgaaacgta
    40441 gaacgttctt accgaccgga tatcgaaatg aattttgccg aaaaaatagg aaacaaaaca
    40501 gtattaaaag acgaaggttt cgaaattgaa gagctaaata cagaaatccg attagctgaa
    40561 catctttaaa aatctcttat gagcagtttt taaataaaaa ataacttgga taacgatcga
    40621 tttttgatca ttgtccaagt atttttttgg tatactagta ccagtaccat ttctaaggag
    40681 tgagtagatg cggataatat caggaaatta tggcgggcgc cgtttaaaaa gtttagcagg
    40741 ggcgaacacc agaccaacta cagataaagt aaaagaatcc atattcaata tgattggacc
    40801 atattttgat ggagagacag tattggatct gtttgcagga agcggtggtt tagctatcga
    40861 agcagtatct agaggctgca gtcatgcggt atgcgtagac aaaaattacc aagcgctaaa
    40921 aatcatcaaa gaaaacatcg aaattacgaa agaaccagag aaatttacca caataaaact
    40981 tgatgcggac aaagcaatcg aacggctagc agcggagaaa caacaattcg actacttgtt
    41041 tcttgatccg ccatatgcaa aacaaaaaat aatcgatcaa atccataaaa tggaagaact
    41101 gggacttttt tctaaaaccg cagttatcgt atgcgaaacg gataaaacag tcgaattgcc
    41161 agaaactgtg gctggattcc atcaaataag aaaacagatt tatggcataa cggccgtaac
    41221 tatctataga aaagagggaa atcaatgaaa cgtgcattat tcccaggaag ttttgatcct
    41281 tttacaaaag gtcacttaga tacggtggaa cgtgcggcta aattattcga tgaggtagta
    41341 attggtgttt ttatcaatac ttcaaagaaa agtttgtttc ccccagaaga aagaatgaca
    41401 ttgatcacaa aagctgtttc tcatcttcct aatgtaaaag tcatgcatca agaaaatcaa
    41461 ttgacggtag aaacagcaaa agagattggt gcagatgcgt tgatcagagg catacgaagt
    41521 atcaaagact ttgaatatga acgagagatt gctcagatga atcatcatct atatgatgaa
    41581 ttggaaactg tcttcttatt agcaaaacca gaatatagtc acgtgagttc cagtatttta
    41641 aaagaagtac tgcactttgg cggagatgtg agcagctact taccgccagt gatcaacgaa
    41701 gctttagctg gaaagcgtga atcaaatgaa agctaaacaa tggttgaaaa cagtactgat
    41761 tatcatattt ggaatgttga tcattggatt tgtagtagtt cccttgccgt attatgtaga
    41821 atcaccggga gccacgatcg atctgaaaga actaattacg gtcaatgata aggaagataa
    41881 aggttctggg tctttctctc ttacctctgt tggtatcagg caagctacag gtttcttagc
    41941 tttaaaagct aaaatgaccc cttttgaaga attgatcagt gaagaagaat tgactggtgg
    42001 ggcgacaaat gaagaatata atcaaatgca acagtattat atggattctt cccaaaatgc
    42061 agcaatcgaa caagcgttaa aacttgcaga caagccttat aaaatggaat tcaaaggcgt
    42121 atatgtcatg agtgtagaga aaacatcgaa tttctttggc aagctttcag ttggagatac
    42181 agtaacaaaa gtagacggga aaagctttca aagtacagaa gcatttatgg attatgtaaa
    42241 aagccaaaaa gttggacaaa caatcgaaat cagttatttg cataatggtg aagaaaaaac
    42301 agcttctggt gatctgatcg agttaccaac agataaaaag gcaggaatag gtatcacgct
    42361 tactgaccat accgagatcg aatcagatac agatgttcgt attaattctg gctctatcgg
    42421 tgggccatca gcgggattga tgttcacttt agaaatctat gaacaagtca ctggtaaaaa
    42481 cttgcgacat ggtaagcaaa ttgcaggaac tggaacgatc aacagtgaag gagaagttgg
    42541 ccgaatcgga ggaatcgata aaaaagtggc aagtgcggat aaagctggcg tagagatttt
    42601 ctttgcacca gatgatacga tttcagacga tgttaagaaa gaatatcctg aaataaaaac
    42661 caactacgaa gaagcaaaag ctgccgctaa aaaattgaat tcctcaatga aaatcgtacc
    42721 agtaaaaaca gtacaagaag cgcttgacta tctagagaaa atgaaatgaa actaaataat
    42781 taaagagggg ttgtgacacg agttctgtca caacccctct ttttcgtcaa aaatcttcac
    42841 gataaaaata aaaacaaaag aaaaaattga cgtaattaga tgttgaaggg acgattttgc
    42901 cagagctcac tgtttcttca attttaaatg aaaggagtaa tgaatgattt ttactggtca
    42961 ttctttgaaa aaagaacaat gatagaaaaa atcagcaaga aaatactagc ttcacccaaa
    43021 ttgatcattt ggatgtctat gatagttctt atcttttgta tcgcaagtgg ttttttatta
    43081 tcaaatttgc tattttatag agaaacagaa gagactgctg caaaagaaat actttcttcg
    43141 tttagttcca gtggagaaga tccatcagct gaaggaaacg atgtagaaga ggatgctcgt
    43201 ccaaaggtca tgtacaccga tatcaaagga agtgtgaagg agcctggtat ctattccttt
    43261 tcttcagaag aacgggtcta tgatgtacta aagcgtgcag gtggattatt agaagaagcg
    43321 gatagcgatc gaatcaactt ttctgcgaag atagaagatc agcaagtcct atatatccct
    43381 gctgtaggtg aagagctgcc agaacatctt gatcagttgg catcctcgga aggaaaacag
    43441 cctacagcag attccgagcc tcccaaaata aatatcaata cagccactcc atcagaactt
    43501 cagcagattc ctgggatcgg atcagtcaaa gcgcaagaaa tcattcgatt tagagaagaa
    43561 aacggatcct tccagaaagt ggaagacctg caggagattt ctggtatcgg tgaaaagaca
    43621 gttgaaaaac taaaaaactt cgttacaatt aaatagaatg attcaaaatc gactggcacg
    43681 agcaataaat ggacgctaat ggatactaag aataatccaa ttctaagagc ttggcaggac
    43741 gaggaggtag tatttttgga taggaaatag cttgattgtt cgcaaagaaa cattaaaaaa
    43801 accaatgctg aatgtctatc tccaaaataa aatatctggg attcatatta tgaatacggc
    43861 tgtcagcggc aataacagtc aagctctacg agaacgcttt gccaaagatg tacttagcta
    43921 tacagcagat aaagtattta ttctcattgg gacgaatgat ctagcagagc ataaacaact
    43981 ttctaaagaa acgtaccaaa aaatctgcag tggatgatag ttcagctgaa aaaagactat
    44041 agttctgatc atgctttctt tatcacgcca ccagcagtcg atgagacaaa acaaaaatat
    44101 cggaataaca agttgatcaa agaatatatc tctgttctca cagaagtagc aaaacgccat
    44161 gattgtgaag tatcgatttt tatacggaat ttcttgaaca aatggattcg aagaattttt
    44221 ataatgggct aatggatgac ggacttcatt tcggcagtga agggtaggat cttttgtcag
    44281 acaggatgat tcgttatatt taaagaatat tttgtttaag caatgagtac tttttaatca
    44341 acttgaaaaa acggaggaat ataaaacatg ttagaaaaat cttcaaaagc atgcgatacg
    44401 aataaagaaa aagttactga taagtcacat aatgaacgca ttccttggga ccagtacttt
    44461 atggctcagg cagtactgtt atctttacgt agtacgtgta cacgtttaga agtaggagcg
    44521 acactcgttc gagaaaaaag gatcattgct ggcggctata atggagcagt cagtggagat
    44581 gtccactgca tagatgaagg gtgttacgtc gtggatggac actgcttgcg aacgatccat
    44641 gcagagatga atgcactcct acagtgtgca aaacttggta tcccgacgga aggttcagaa
    44701 atctatgtca cacattttcc atgtttggcc tgtacaaagg ctttgttgca agctggtgtg
    44761 aaagggatca attatctcca tgactatcga aatgatcctt atgcccaagc gttgatcgaa
    44821 caattaggtg tatctgtaca ccaagttgct ttagactcac agcatttttc aaaacttcaa
    44881 aatgaattaa caggaaaaca tgtctagcgt tttagaaagg catgttcgaa atcggttgat
    44941 ttttccggca attacgtcga tgattatctg tttgttgtat tacactgaca attggggtta
    45001 tcgtttgctt cttgccggaa tttttttatg gttttcgcta aaagaaggac gttttatcgc
    45061 gtacttgtgt attttgtgta gcataacggt atccatttct tataggctac aagagtattc
    45121 atttttagag gaaaaaacaa catctgcgca aattactgta tttacagata cgattcgtgc
    45181 aaatggtaat tttttgacaa tggaaggaag gttatcagag aataaacaaa agctccagct
    45241 ttcttatcaa gtaaacacag aagcagaatt gaaaacatgg cttaacttcc gaggaaaggg
    45301 aatagaattg actgctgaag gcgagttcat ctctccagca aaaaagcgga atctttataa
    45361 ttttgaccaa gaagcttact tcaggaacca tagaatttct ggacggttcc aaattcaaaa
    45421 gattgaacag atcaccatgc aaaatcactg gcgaaactgg cttcagagaa aaagaggatc
    45481 ttttatctcc tttgtccaat ctgaatttcc gcaaaaaaca agtgtatata ttaattcttt
    45541 attatggggc tataaagatg caggattcag agaaccagaa gaaattttta gggagagtgg
    45601 tttgctgcat ctgttcagtc tatcgggtct acacatccaa ttttatttag ggtggctgta
    45661 ttatttattt cgacgtatcg gatggccact acacgtcagt attattccgt tgagtctact
    45721 aactatctgt tatgtttcta ttgcaggaag ttctatttct gttttgcgtg ctagtttgct
    45781 gtttttattg cgattgctag tcaaattgct gaataagcat tattccacca tggacttatt
    45841 tgcagttgtc ttttggcttc ttttactatt tgatcctcga tttctttttc atgcgggtgg
    45901 acagcttagt tttttcatga gttttttgtt tatcctgatt tcttttgatg gagattggtt
    45961 gaaaaaaacg gcctctcacg tcctgtttac tatgatcacg atgccgttga ttgtatggca
    46021 tttttatgag tggcctattt taggtagtct ttttacatta ctgattgcac cggtattcaa
    46081 gtttcttttt cttcctggtg tgttatttct cacactcttc aatcgctggc tgccggaaac
    46141 tttacttttg ctgatagaag agggattaat cttatttgag cgaataatcg atttttcttc
    46201 agggtcgtct ctcattatag gacgtttgcc ccttgtgcta tctgggatgt atattttcgg
    46261 attactgatt tgtatggata ggttgaaaga acaacctgtg aaacacttgt tttatgttgg
    46321 tcttttttct tttatttttt tgactttgcc atttttacgc ttttcttcaa cgatcgcttt
    46381 tatcgatgtc ggtcaaggag acagtatctt tttgcaaagt ccttttcgaa aagaaacgat
    46441 tttgatcgat actggaggtc agttacactt tgaaagagaa aagtgggcgc aaggtatgat
    46501 acgtcctcct gctgaaagaa atatcgttcc atatctaaaa ggtcagggga taagtgtaat
    46561 cgataaactc atcttgacac acgacgatac ggatcatgtg ggagaattac ccacgttatc
    46621 tcagcatttt actatcaaaa aaatttatat cggttggggc gctggacgaa atgagccatt
    46681 acaaaggcat ttatctgaag ctcaaaaaaa tggtactgag atcattgaaa tcaaacatgg
    46741 ggacaggatc agcggttatt atgatcttta tgtattgact ccttttgaaa agggagaggg
    46801 aagaaatgaa gattcgattg gtctatggat ggaatataac aataggcgct ttttattttt
    46861 aggagatttg aatcaagcaa tggaaaaaca attgcttttg atttatccta atctgaaagc
    46921 cgatgtagtc aaattaggtc atcacggtag ccgtacgtca agtaacacag attttctttc
    46981 ccatattgaa gcaaaacatg ggattatatc ctgcggcgta aataatcgtt atggtcaccc
    47041 gcacagcgaa gtattggaga cactagaaga aaatcagata aaaacatggc gaacggatca
    47101 acaaggaatg atcacctatc gctggcatcc agtttttcat cctcatgggc tagtggaaac
    47161 aatgatagac tagtaattct catctgctca tggtaggata atttttgaaa gtggtgagta
    47221 atttgagtat acaagcagag ttacaaaaaa tacgtaaaga aaaacttgca tcttgttact
    47281 tgattttagg aacagaaaag tttctccaag atcaagttcg gacagaaatt gtcaaaaaaa
    47341 tccaattaga gggcgaagat gacttaaatt ttttaagttt tgacatggaa aatgcaagtt
    47401 tagatgaggt agtagctgaa gcagagacgt tgccgttttt cggagatcaa cggttagtat
    47461 tcgtagagaa tccttatttt ttaacaggtg aaaaagtaaa caatggaatc gaacaaaata
    47521 ctgatttatt gacggcttat ttgaaagaac cattagaatc gactgtatta gtattctttg
    47581 cgccatatga aaagttggat gaacggaaaa aagtaacgaa acaattgaaa aaaacagcaa
    47641 ttatcatcaa tgtccaacag ttgaatgaaa aagaagtacg tcaatatctg atgaatacct
    47701 tagagaattc ctcaatcaaa atggaacgaa gtgcaattga tttattcttg aggttgaccg
    47761 acttagattt atccaaaatg atgagagagt tacagaaatt ggtcctttat ggacaaaatc
    47821 aacagcaaat cacggtaaga gaagtagaag aattagttcc taaaacgtta gaacataata
    47881 tttttgacat gacccaatat attttaaaag ggaagacgga acaagctttg cgtttatacg
    47941 aagatttagt tatgcaaggg gaagaaacaa tcaaaattaa tgcgattttg ctttctcaat
    48001 tacgtttatt tttacagaca aaatttcttg taaagattgg ttatcagcag gcaaatattg
    48061 ctgaaacatt gaaaatccat ccatatcgtg taaaacttgc catgcaggaa gtaaaaaaat
    48121 tcgatgaaca tttgctggta cagttgtttg atcaattagt tgagatggat tatcaaatca
    48181 aaacgggaca aatcgaaaaa gaattaagtt ttcaactatt cgttttgcgc acagggcagt
    48241 tgttaagaaa tcgataagaa gaaagacgag ggcaaagcat gcgggaaggt cgtttgtttt
    48301 tgtccttttt ttgacaaata aaaaaatcgg ccgaagccga ttcttttatt tagcgatttt
    48361 tttgcttaaa cgagatttgt cgcggttagc tttgtttttg tggattagac cttttgattc
    48421 agccatatca atagctttaa cagcttcttt atataacgca tctacgttgt cagcacctga
    48481 agctacagca tcttcaaatt ttttgattgc agtacgcata gcgcttgttt gagatgaatt
    48541 tttcacatta gcgttttcgc ttgtacgaac acgtttgatt gcagattcaa tgtttggcat
    48601 tagtttcacc tccgataact taagttctta cgcgtgttac cgcataattc aacattcatt
    48661 attataccta aaggcagcgt gctttgcaat atgaacatga caagtttttt tccttaacag
    48721 tcttttatta ggattttttt tcagtaaaaa cggatagtac aagctgaaaa aaatcaaaaa
    48781 gacgctattg tgggaggcaa tagcgtcaaa ccaaactaga tttttattta tctatttaaa
    48841 caaagtttga atgggaatgt ttggtactaa gttattatat aacaaagaga accgtttgca
    48901 aagttttttt tgaaaaggga tacgattccc tgttgttctt tgtttttcta ttaagaaact
    48961 gcagttattt tataaccagt atcctttgat cagtaaaggc tattctggtg taccgattat
    49021 tttaatgtat tcatcgatat tttttatcaa catttttttt atgaccaact ggttccgacg
    49081 gttccatttg ccacttactt ccagcacata tttatttagg ggcaaacgta agatatattt
    49141 tgccaaatag cgatctttaa gcaggccatt gatcacacgg tcctcaagct gcaagttgat
    49201 cccagtcagc atcattggct gttcttgtaa aacgtacgta tcaattaaaa gaccttcaaa
    49261 agtttccaca agcgtcttcc tttcttttca aagtaacctg aaaacaggca ctaattcttc
    49321 cattttgata ttcgttgaag tggatgcgat cattctttct tttgtccact gtaatctagt
    49381 ataacaaaaa agagcagaag agccaaaaag aaaaaagagc atcgaattct ataggaagtc
    49441 tcattggcac ggcctaaatt attacaaaac attgattaaa aaaagcccct gcatcgcagg
    49501 agcatcccct atatcgtttt aataggtcaa tcaaaaagca gtatcaaaca cattttgtat
    49561 caaatcagga aataatagat aagctaagcc cagaatcaaa agtaccgcta gaagaaacca
    49621 gccgattgtt cctatgaaat actttaattt ttcgaacatt gtatcacctc gttgtcagta
    49681 tatcacggat cagtaaattg ggggtgttaa gaatctccta aaatagacaa aatttgttct
    49741 attttcctaa agcaaatact tgtaagatac agtaagtgat accagaagca atgaccggtc
    49801 cggcggcgat tcctcttaag aagacaacac ctaaaatcgt gccgaaaaca agtgcaacag
    49861 tgatttgtgg atcagaagca atcaatccta cacccttgga agataagaca gccactagcc
    49921 caccgcaaaa aacagctacc cagccaatag gggatttaaa ggcttctaat agatcacgta
    49981 gaccgatttc tcctgttgcg atagggatta gaatagccgc tgtgatgatc gtcaccccaa
    50041 tattgattcc tttgccttga agccaaggga aaaaggaacg ggaggctggt atgagcttca
    50101 taatcaaaac aaaagctgcc gctatcatca gactttgatt tttagctaaa attgctacaa
    50161 gtaaaataat tcctaaaaaa agccaacttt ccatgaaata tattcctcac tttcttcgaa
    50221 acaatcataa catgttttta gaaagttaca aaagtaggaa ttcatccttc aagacctatt
    50281 cataagctgt ttttttcata aaataaacaa aatcataaaa aaacactttg cttatttgac
    50341 agaagacagc cgcgctttgt atagtggaca agacttacat ttttttgaag aatcagaaag
    50401 atcaggtaaa ggtcttagta aacgcaagcc attcagaata accaatattg tgcttccttc
    50461 gtgtcctaca actccaagag gtagatttaa aaattgcagg aagttagaag caatcaacaa
    50521 gagaataaca agaatcgaaa aaataatatt ttgtttgatg atccgccgca tttttaaaga
    50581 tagccgatga ctgtagacaa atttatttaa gtcgcttttc attaagacga tgtctgcgat
    50641 atccatagcg gcatctgtcc cttgccccat agcgacacct aaagaagcgg ctgctaaagc
    50701 aggcgcatca ttgactccat caccaaccat cgcatttact tggtaaagtt cattctcttt
    50761 tttgactagt tgtgtttttt cttccggagt acagcttgca tagtaatgtt caatccctac
    50821 ttgttcagca atggcctttg ctgtgccaga atggtcgccg gttatcatac ttgtatggat
    50881 gttttgggat ttaaagtagg aaattacttg ttgggtattt gcttttggaa tatctagcag
    50941 acctaaaaca gcaattaact gctgatcttt agaaagataa atcacggttt tgccttgatt
    51001 ttccaaacgt tcgatcattt ccgcaatctc tttgctgatt atcatcgtct caggatcata
    51061 tgcgtgcttg ccaactttcc attgcgcacc taaataggta gtttgtaatc caaaaccagt
    51121 aatttcttct attggtaagt attggatttc ttcaggtatt gtgcaatcga aatattgcaa
    51181 aatcgcatga gcaagtggat gcgtcgtttt ttgttccata gcaacaagaa gttgttgtgc
    51241 caaatccttt tcatcaaaga aaaagctgtc agttacaact ggttttcctt tagtgagcgt
    51301 tcctgtttta tcaaaggcaa tcgcttttaa ttcagaaagc ttttctaaat ggataccgcc
    51361 tttgattaaa atcccatttt ttgcagaatt tgaaagagca gctagagaag ctggtgtagc
    51421 agatgcgaca agcgcacaag gagaagccac aactaataat accattcctc gataaaagct
    51481 ttcatcccaa ctccaaccta ggaaaaagtg ggggagaagg atcattagag gaacagcaag
    51541 caaaatcaat tttacataat tattttcgat tcgttcgata aatgaagctg tttgagttgg
    51601 cgtattctgc gcttcttcta ctaattggat aatcttagca aagacagttt cggaactcgt
    51661 ttttgttact cgaatcgtga tgggatttcc ttgattcagc gttcctgcat acatctcatc
    51721 gcctaaatat ttttctacag gcacagattc accgcttaat gcagactcat cgatcgttgc
    51781 ctgtgtgctt tctaaaaagc catctatcgg aacagctgct cctttagcga caaataccaa
    51841 gttatccacc tttagttgag aaacatctac ttcttgcatt tgtccatttt cttttaataa
    51901 ttgggctttt tgtggttgaa gattcatcaa agcagtaatt tctttttgac ttttattagt
    51961 tgtgtattcc tctaatgcac cgcttaaaca aaagatgaat gtcaacattg ctccttcaaa
    52021 gtaattaccg atcaaacagg caccaatagc agctaaagcc atcaataaat ccacattcag
    52081 tgtccgatca ttccacaatt ctttcaagcc ttccgatgtt tgtttatatc caccgatgat
    52141 aatggcactg atataaaaaa gtggggtgat ggtaagagag aatcggtcga agataaaacc
    52201 gaagatcata aataaaaggc agccgattgt tgctgcaaaa gcttttttct gattagtcat
    52261 cgttattaga cctccttgtc aaaacaagga tagcataata aaaatgtaat tgataataat
    52321 aacagctaaa tgagaacgat aatggttatc atttggtgat taagcttgat gttgttttta
    52381 ttatttataa tgattattat taaagaaaat aaaaaaccag aacatttctc aaataagaga
    52441 agtgttctgg ttttttctac attgcaataa accaataacc aatcaaaatg ataccaagga
    52501 taatacgata ccagccaaaa gcggtaaagt cgtttttctt caaatagctt agtaagaatt
    52561 tgatagctaa gacggaaacc acaaaagata cgaatgttcc tacaagaaga acaacagttt
    52621 cttccatttt gaatgaattc ccttcagcta aatatttgac gatcttcaag ccgcttgcgc
    52681 caaacatgac aggaatccct aagaaaaatg aaaactctgt agcgacaaaa cgcgaagcac
    52741 caatcaagat agatcctagg atcgttgcgc cagaacggga tgttccggga acaagtgcca
    52801 agacttggaa taacccaaca agaagagctg cttggtacgt aaagtcattc agagaagtcc
    52861 aacgaggtgt tttgtttttg ttgcgttttt cgacaataat aaaggcaata ccgtaaacga
    52921 tcaaaacaat ggcaactggt aagaacttgt ggaaatttgc ttctaaccaa tcatccaaag
    52981 gcaaaccaat gatgatggct ggtatgcaag caacgatcac tttaaaccaa agtgtccacg
    53041 tatctttttt ttctaccgtt gatttacttg gagaaaatgg gtttaacttg tgaaaataaa
    53101 gaacgacgac agccaagatc gcccctaatt ggataacgac attgaacatc gacataaatt
    53161 gtgaactggc atccagtttg atgaattcat ctgctaggat caaatgacca gtactactga
    53221 tgggcagcca ttccgttatt ccttcaataa taccgagaat cactgctttg ataatatttg
    53281 caaaaaacat aaattccttc cttcccaatt aagatacatc ttatagtata ccgttatttt
    53341 ttgagaaacc caatctgttt tttaatatta agaaaaactt gagaaataaa gcagataagt
    53401 acacgaagag aaaaaagaag acaaagccct cgttcagact ttgcctttta tgattctctg
    53461 gtaaaaatta aaatatcccc attatagaaa cgagtcgcga ctatgtgttt tcccgttatc
    53521 gatataagac gtatcattga tgccgtggat agaaaatcga ccgtttgcat aagtgacctt
    53581 tgttacgctg ccatttaaaa gcccagcacg aacaggctgt ttaggatcga tcagattaag
    53641 caaaaaggcg atcgtcaaac catgagatac gactaaaaca tttccaccac catttttttc
    53701 gcagtgatgg gcgatatctt caaatcctgt ccatacacgg tctcgcaatg tttcataagt
    53761 ttccgcccac ccagcggtat ctaagttgta tacagcatta gcaatttgtt caaaagaaac
    53821 ttctgtggta aacatttcat catatgtttt aaaattcaat acacgaggga tcacacccca
    53881 catttccatg tcatatccac cttcaagaga cccgaaacac cattctctaa tccttttttc
    53941 aataaaataa ggaatttctt ttcccttaga atgttctcct agaataatac gggcagtttc
    54001 gattgcacga ccactgtcac tagaataagc aaatgaaaag tcgacatttt ttaacccgcg
    54061 acctaaataa tgaatgcctt cttgtccttg ctttgtgagg ggtgtatcac accagccttg
    54121 tactcgttca attgtattga acatcgtttt tccgtgtcgt acgatataaa gtgtagtttc
    54181 tgtcatttta ttctcctcct aagtcgtttt aacgattgaa aaaaggattt gtcctttttt
    54241 cctgttcaat cgtcgttgca tcgccatgtc ctggatagac tgcaaattca tcaggtaata
    54301 caaacagctg ggtccgaata ctatgaagta attgttctaa attccctgta tacagatcgg
    54361 ttctaccgat acttcctcta aacagggcgt cgccagaaac gacaaaatca tcaaaaataa
    54421 agctgacgct tcctatagaa tgccctgggg tagggacgac gcgaaaagac atgtttccta
    54481 aagtataagt tttcatttca aattcatatt ctgcaggcga gacaataaca tcagcaatat
    54541 catcatgtct accgagtcca gaaagattca aaatcggatc acctagccat ttttgctcta
    54601 gtgggctgac ataaactggg atttgataat acgcgcgtaa aggttccact gcaccgatat
    54661 gatcgtagtg agtatgggta agcaaaatcg ctaccggctg ttggtttgtt tttttgattt
    54721 cttgtttgat tcgttccgca tcttctccag ggtcaatgat caaaagtgct tcttcgttgt
    54781 agaccaaata acagttttct tcaatcattc ctgtttttaa tctttcgata tgcatgtgca
    54841 ttcctccttg atagccaaaa cttctttcat ccattagtat aacgcattca ttgctaggaa
    54901 acaaaaacag gtacttattt ctctttactt atctgaatta tcagactata tgaaaagtat
    54961 ttggatattc taaagagaag gaaagtaagt tttcatagca ttttaatatg tccttgttac
    55021 attagattca tccaaaaatc caaattctat atcctatatc cctgcctaat cagcagggtg
    55081 tttttttatg tttggaaaga gagctctttt tgctaaacta ggttttttca ggtaatctta
    55141 gagagaaaga ggtggtggaa atgatcaaac agtcaaaaat atctgtgcgg cacttagtag
    55201 aatttatttt gcgacgtgga agtatcgaca atcgtaaaaa aagtaaccat actgcattag
    55261 aaggagcgag aatccaccgc aagctccaaa aagatgcggg agaaaactat gaaaaagaag
    55321 tctttttaaa aacaacagtt caattagatg aatattacct gatcgttgaa ggccgtgcag
    55381 acggtatttt caaaagagac ggtatttatt atatagatga aatcaaaacc tccgaaccac
    55441 gatttgaaga tttagaacca gaacaagtgg aacttttctt tcatcaagca agggtgtatg
    55501 cctatatcta tagtcaagaa catgatttac aagaaataaa tctgcaattg acttacttcc
    55561 agacggcaga agaagtgatc acgagaaagg ttgaacatca gacaagagag cagttagaaa
    55621 ctttttttaa aaagctgact gaagattata aagaatggct tgtttttcaa gaaaactggc
    55681 gcactgtacg caatgcctct ttgatggctt tgaaattccc ccatgatgag tataggaaag
    55741 gtcagcgtga actagcggta gctgcttata aaacgatccg tacgaaacag aaattgtttg
    55801 tagaagcacc taccggaaca ggaaaaacaa tctctacgtt attccccgct ttgaaagctg
    55861 taggggaaga agagggagaa aagatctttt atctaacggc taaaacaata actagacaag
    55921 tagctgaaga tgctatgaca gcattaaaag atacaggagc tgaagtaaaa agtgtcactt
    55981 tgacggcgaa agacaagatc tgctttttag atgagacgac ctgtaatcca gatcagtgcc
    56041 catatgccaa tggttattac aatcggatta atgaaggttt atgggatctt ttgaatcatg
    56101 agaatcagat cactcgtgaa gtcatcgaaa cttatgcaag aaagcataca ctttgtcctt
    56161 tcgaactatc attagatgtc agtatctggt gtgacgtaat cattggggat tacaattatt
    56221 tatttgatcc aactgtttat ttaagacgtt tttttgaaga tgaaaaaaac gaggactatc
    56281 tgtttttgat tgacgaagca cataatttgg tgaatcgttc ccgagagatg tattcggcag
    56341 aactatctta tgaaaaaacg aaacgaagta aggaagctat accaaaggaa ttcaaaaaac
    56401 ttcatcgccg tttcaacaaa ctattaaaag aatttgattc gatccgagaa atagcaaaag
    56461 aagatcattg ggattatcat catcaaaaag caccggctga atctttagta aaggcaggtt
    56521 atcaattaag cgaaaaaatt aaagaatggc tggcagaatt tcctgagcac ccatcacaag
    56581 aacaattgct tccttattat tttgatttgc ttcatttttt gaaggtcagt gaattttatg
    56641 atgatcacta cgaaacaaca gtcgaaaaaa cgtatcgcga tctgatagta aaagagtttt
    56701 gtattgatcc aagcttgttt cttgagcagt cgttggataa aggaaaaagc agtattcttt
    56761 tttctgctag tttttcacca ctctcttatt atcaggaaac actgggggga caaaaaagtc
    56821 tggcttacaa actgccgagt cctttcccag aaggaaacca gcaagttttc atcgcaaatt
    56881 acctagagac gacttatcga aaaagggaac acagtctggc aaaattagta gagacgattc
    56941 atgcttttgc tgatggaaag gtcgggaatt atttcgtttt ctttccttct tatcaatatt
    57001 tagatcttgc ggtggaagca ttcagacagc aatatcccga cagcaatgtg ctaatccaag
    57061 aaacggacat gaatgaggaa gaacgcgaac gatttttaac aaaatttcaa acaaatcccg
    57121 ctgaaacatt gattggattt tgcgtacttg gcgggatttt ttcagaagga atcgatttga
    57181 gaggggaccg attgatcggc agtatgatcg taggtgtagg tttgccgcag atgaatcatg
    57241 agcaggaact gatcaaatca tattatgatg agaaggaaca ccttggattt gcttacgctt
    57301 atcagcttcc tggaatgaac aaagtcttgc aagctggtgg tcgagtgatt cgtggcatgg
    57361 cggatcaagg aatcgttgta ttggcagatc aacgattttc tagtttttct tatcgacgtt
    57421 tattcccaca acattggcaa acagcaagag aagtacgaag tgttggggaa ttggaagaag
    57481 gaatacagcg tttttggtta tcaaaagaag cagtaaatca aaaaaacgag gaatgacaga
    57541 cgtcagcctc gttttttgat taacgatagt tagtgaattg caactcgatt ggtaagtcaa
    57601 gtttacgtaa taaagcaatc acagcttgta gatcatcacg gttcttacct gtcactctaa
    57661 tctgatcttc ttggatttgt gcttttactt tcagtttttc atttttgata gctgtagtga
    57721 ttttcttcgc gttttcacga tcgattccgt tgaccaaatc ggcagtttgt cgagctttgc
    57781 cacctagagc gtgttctgat tcggaaaaat ggatattttt gattggcaca tttcttttga
    57841 tcagcttacc aaataataca tctttgatct gttcgatttt gaaatcatca tcgctcaata
    57901 caactagatt gctgttctct aatttgattt ctactgtaga atccttgaag tcaaagcgat
    57961 tggacaattc ttttgttgtt tgctgaatcg cattttttac ttcttctgta ttgacttctg
    58021 atacaatgtc gaagctagca tcttttgcca taggaaccct cctgatatac atataaatat
    58081 ttaccataca tctatcttat cataggatta gggcagattc ttacctgttt gctaaaattc
    58141 ttctcatttg agttcgaagt attttatttt aatagataaa ctgttattct tacatttgga
    58201 ataccaaagt aggggagagg tgcttgtgag taaaattatg actgcgtatc ataaaaatga
    58261 aagattaaag aaaatagtgg ttattttgat aaccggattg accgctgcgg tcgctttaaa
    58321 ttattttttg attccagcca atgtcttttc tgcagggatg aatgggatcg ctcaaatcat
    58381 ttcctcgctt ttatatgaat ggtttcatat caagatagac acaggaacat ttatttttct
    58441 tttgaatatc cctgtgtttg tattagggtt tctcaaagta ggaaaacgag caacgatcct
    58501 tagttttgtg aatgttgtat gtgtatcggt gatgacgatg ctgcttccag tcggacagat
    58561 cactgataat attttgatga atgccctagt aggcggtgtt ttattaggtc ttggcgtagg
    58621 attatcttta aaaatgggct ttacaactgg tgggatggat atcatctctc ttgtactttc
    58681 acaaacaact ggaaaaacag tcggaaacta catgctgatt ctaaatggta tcattgtagt
    58741 catcgcaggc ttcttcttta actgggaaag tgccttgtat acgattattt ccatttatgc
    58801 aatgactcaa gtaattgatg ccatccacac gagtcatcaa aaagtaacag caatgatcgt
    58861 taccgtcaag ccagaagagg taacagaaga actagcaaaa cggatggtac gtggaatgac
    58921 attactgccg tctgtcggtg gctattcaaa aaaacaaggg aacatgatca tgatggtcat
    58981 cacccgctac gaaatgtatg atcttgatca gatcgttcat gaaatcgacg acgatgcatt
    59041 tatcaatatt ttaccaactc attcagtatt tggccggttt gcaaatgaaa acgaacaaaa
    59101 aatgtatcga acaactggcg tattgccaga aataaaaaat cgttcacaaa aaaaatgagg
    59161 aatcaggttt attttagaat aaatttaatc tattacatct aataagaaca tttttataaa
    59221 tttaaacgag aatcttactt ctaaattctc atttacaagc agctaaaaaa agagtatgat
    59281 aaataaaaat cgtgttaagg agtgtcgtac gatgagcgaa gcaaaccaag aacggtctgg
    59341 acaagaaata gaactaatca aagaacgtat tcttgctgcc ttggaaatgg tgattgatcc
    59401 tgaattagga atcgacatcg tcaatttagg cttgatttat gatatagaat tcaatcctga
    59461 aaatggagaa acagtcatta agatgactct aacaactatg ggctgtccat tagcagatat
    59521 tttaacagaa tctatccatg acgcattaaa agaagtgcca gaagtaacga aagcagaagt
    59581 caaactagtc tggtatccag catggacgac agataagatg agccgttatg cacggattgc
    59641 gttggggata cgatagaaat cttggctgac tagctatgag aagcaaatag gaaaaacaaa
    59701 aaagcctttt atcctttcta gaagaaaaga gataaaaggt ttctttgttt ataaaatttt
    59761 gtctgctata ttataagtta attaaataaa tgtgttctat tgataaagga cattcaaatc
    59821 cctttccttt tggaatcctt cttttttaca tcagtttgat tttcgtatag tattctttct
    59881 catcttcacg ataaatcgca gccccatttt tttgttgtgc tttaagactg ccaagatttt
    59941 tttta
//
LOCUS       DAPBCF010000011        59488 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.011, whole genome shotgun sequence.
ACCESSION   DAPBCF010000011 DAPBCF010000000
VERSION     DAPBCF010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 59488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.011"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            271..837
                     /gene="amaP"
                     /locus_tag="RD508_000865"
     CDS             271..837
                     /gene="amaP"
                     /locus_tag="RD508_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HDT7735480.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            850..1038
                     /locus_tag="RD508_000866"
     CDS             850..1038
                     /locus_tag="RD508_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HDT7735481.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1051..1608
                     /locus_tag="RD508_000867"
     CDS             1051..1608
                     /locus_tag="RD508_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7735482.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1640..1882
                     /locus_tag="RD508_000868"
     CDS             1640..1882
                     /locus_tag="RD508_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7735483.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            2223..3437
                     /locus_tag="RD508_000869"
     CDS             2223..3437
                     /locus_tag="RD508_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HDT7735484.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            3468..4895
                     /locus_tag="RD508_000870"
     CDS             3468..4895
                     /locus_tag="RD508_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7735485.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            4918..5844
                     /gene="glsA"
                     /locus_tag="RD508_000871"
     CDS             4918..5844
                     /gene="glsA"
                     /locus_tag="RD508_000871"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDT7735486.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            6052..7512
                     /locus_tag="RD508_000872"
     CDS             6052..7512
                     /locus_tag="RD508_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735487.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            7733..9496
                     /locus_tag="RD508_000873"
     CDS             7733..9496
                     /locus_tag="RD508_000873"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDT7735488.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            9580..10038
                     /locus_tag="RD508_000874"
     CDS             9580..10038
                     /locus_tag="RD508_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HDT7735489.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            10147..10830
                     /locus_tag="RD508_000875"
     CDS             10147..10830
                     /locus_tag="RD508_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDT7735490.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            10977..11591
                     /locus_tag="RD508_000876"
     CDS             10977..11591
                     /locus_tag="RD508_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDT7735491.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            11607..11813
                     /locus_tag="RD508_000877"
     CDS             11607..11813
                     /locus_tag="RD508_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735492.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            12354..13484
                     /locus_tag="RD508_000878"
     CDS             12354..13484
                     /locus_tag="RD508_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDT7735493.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            13576..14331
                     /locus_tag="RD508_000879"
     CDS             13576..14331
                     /locus_tag="RD508_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7735494.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            14389..16428
                     /locus_tag="RD508_000880"
     CDS             14389..16428
                     /locus_tag="RD508_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HDT7735495.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(16537..17688)
                     /locus_tag="RD508_000881"
     CDS             complement(16537..17688)
                     /locus_tag="RD508_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDT7735496.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(17842..18372)
                     /locus_tag="RD508_000882"
     CDS             complement(17842..18372)
                     /locus_tag="RD508_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDT7735497.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(18471..18821)
                     /locus_tag="RD508_000883"
     CDS             complement(18471..18821)
                     /locus_tag="RD508_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HDT7735498.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(18978..20507)
                     /gene="ahpF"
                     /locus_tag="RD508_000884"
     CDS             complement(18978..20507)
                     /gene="ahpF"
                     /locus_tag="RD508_000884"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HDT7735499.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(20517..21080)
                     /gene="ahpC"
                     /locus_tag="RD508_000885"
     CDS             complement(20517..21080)
                     /gene="ahpC"
                     /locus_tag="RD508_000885"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HDT7735500.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(21224..21886)
                     /locus_tag="RD508_000886"
     CDS             complement(21224..21886)
                     /locus_tag="RD508_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7735501.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            22070..23716
                     /locus_tag="RD508_000887"
     CDS             22070..23716
                     /locus_tag="RD508_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDT7735502.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            23707..24789
                     /gene="uxuA"
                     /locus_tag="RD508_000888"
     CDS             23707..24789
                     /gene="uxuA"
                     /locus_tag="RD508_000888"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDT7735503.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(24897..26450)
                     /locus_tag="RD508_000889"
     CDS             complement(24897..26450)
                     /locus_tag="RD508_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7735504.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            26598..27887
                     /locus_tag="RD508_000890"
     CDS             26598..27887
                     /locus_tag="RD508_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7735505.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEVAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKLEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFASPETKNKQ
                     LPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            complement(28013..29092)
                     /locus_tag="RD508_000891"
     CDS             complement(28013..29092)
                     /locus_tag="RD508_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7735506.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVIALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(29201..29641)
                     /locus_tag="RD508_000892"
     CDS             complement(29201..29641)
                     /locus_tag="RD508_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7735507.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(29698..30108)
                     /locus_tag="RD508_000893"
     CDS             complement(29698..30108)
                     /locus_tag="RD508_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HDT7735508.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(30289..30723)
                     /locus_tag="RD508_000894"
     CDS             complement(30289..30723)
                     /locus_tag="RD508_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7735509.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(30823..31671)
                     /locus_tag="RD508_000895"
     CDS             complement(30823..31671)
                     /locus_tag="RD508_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7735510.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            32060..33826
                     /locus_tag="RD508_000896"
     CDS             32060..33826
                     /locus_tag="RD508_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HDT7735511.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            33928..35187
                     /locus_tag="RD508_000897"
     CDS             33928..35187
                     /locus_tag="RD508_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7735512.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            35334..36635
                     /locus_tag="RD508_000898"
     CDS             35334..36635
                     /locus_tag="RD508_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7735513.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            36638..37489
                     /locus_tag="RD508_000899"
     CDS             36638..37489
                     /locus_tag="RD508_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7735514.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            37502..38317
                     /locus_tag="RD508_000900"
     CDS             37502..38317
                     /locus_tag="RD508_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HDT7735515.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            38468..39634
                     /locus_tag="RD508_000901"
     CDS             38468..39634
                     /locus_tag="RD508_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7735516.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            39864..40511
                     /locus_tag="RD508_000902"
     CDS             39864..40511
                     /locus_tag="RD508_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDT7735517.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            40595..41538
                     /locus_tag="RD508_000903"
                     /pseudo
     CDS             40595..41538
                     /locus_tag="RD508_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
     gene            41673..43124
                     /locus_tag="RD508_000904"
     CDS             41673..43124
                     /locus_tag="RD508_000904"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HDT7735518.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     FFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            43145..43981
                     /locus_tag="RD508_000905"
     CDS             43145..43981
                     /locus_tag="RD508_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDT7735519.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            43981..44640
                     /locus_tag="RD508_000906"
     CDS             43981..44640
                     /locus_tag="RD508_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7735520.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            44766..45455
                     /locus_tag="RD508_000907"
     CDS             44766..45455
                     /locus_tag="RD508_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735521.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            45461..46417
                     /locus_tag="RD508_000908"
     CDS             45461..46417
                     /locus_tag="RD508_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HDT7735522.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            46461..46973
                     /locus_tag="RD508_000909"
     CDS             46461..46973
                     /locus_tag="RD508_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7735523.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(47229..47777)
                     /locus_tag="RD508_000910"
     CDS             complement(47229..47777)
                     /locus_tag="RD508_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7735524.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(47866..49047)
                     /locus_tag="RD508_000911"
     CDS             complement(47866..49047)
                     /locus_tag="RD508_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDT7735525.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(49283..50791)
                     /locus_tag="RD508_000912"
     CDS             complement(49283..50791)
                     /locus_tag="RD508_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HDT7735526.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            50950..51141
                     /locus_tag="RD508_000913"
     CDS             50950..51141
                     /locus_tag="RD508_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735527.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            51344..52261
                     /locus_tag="RD508_000914"
     CDS             51344..52261
                     /locus_tag="RD508_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HDT7735528.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            52254..53327
                     /locus_tag="RD508_000915"
     CDS             52254..53327
                     /locus_tag="RD508_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735529.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            53475..53993
                     /locus_tag="RD508_000916"
     CDS             53475..53993
                     /locus_tag="RD508_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735530.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            53974..54366
                     /locus_tag="RD508_000917"
     CDS             53974..54366
                     /locus_tag="RD508_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HDT7735531.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            54442..55377
                     /locus_tag="RD508_000918"
     CDS             54442..55377
                     /locus_tag="RD508_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HDT7735532.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            55510..56289
                     /locus_tag="RD508_000919"
     CDS             55510..56289
                     /locus_tag="RD508_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDT7735533.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFAMTAWTGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            56282..56599
                     /locus_tag="RD508_000920"
     CDS             56282..56599
                     /locus_tag="RD508_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDT7735534.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            56843..58453
                     /locus_tag="RD508_000921"
     CDS             56843..58453
                     /locus_tag="RD508_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7735535.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            58610..59458
                     /locus_tag="RD508_000922"
     CDS             58610..59458
                     /locus_tag="RD508_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7735536.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        19737 a        10498 c        11636 g        17617 t
ORIGIN      
        1 taaatagaat cttgtaataa taactgagca taatctttgc aatttttaat cttgaataat
       61 atcctttaag tatagccagc aatcaaaagt aaatagagaa taagtaagca attgttattt
      121 cagtatcaga ctggcaataa aacgccgtta tgatccagca atgtttggta gcgctttatt
      181 tactgatgct atgctaactg ttcgctatct atactgtgat tgtcggtaga gttatttaca
      241 gggtaaaaat aagtttatag gaggtggaaa atgaataagg ggttaaaaat aatcggtgtt
      301 atcatgagtt tactgctact ttcagtattt ctagcgattg cgttgatcaa tgcgccgtat
      361 attatgcctg aacaattgga acgatttcgc ttctttactt taacgaatta ctacatgcaa
      421 caatatattt tctgggcagc tgtagtattt gccgttcttg ctattatcat cttgctagtc
      481 gttcttttct atccaaagtc aagaggaact ttcgttatga aacgggaaga tggcaaacta
      541 acaatcgaca aaaaagcgat cgaagggttg gtacgttccc atttacacga agaagagttc
      601 attcattcac ctaaagtacg gatacgttca acgaaaaatc gaatccatat ccatgtcaac
      661 ggagacttga aacgaacttc ttcattagta gggaaaacag gtgtattgat gcaagatatc
      721 gaagaagaag taactaaagt actcggaaca aaagaaacgg tcaaagtggc agtcacatac
      781 agcggttatg aagaacaaga agatacaaga gactacaagc actctcgagt ggaataggag
      841 ggccaaataa tgaaagaact attttcagca tacaagctcc ctattatctt tgggggtctt
      901 ggactactgc tagctgtttt atggttaacg attggatttt tcaagacatt gttgatcata
      961 atcatgacag caattggcgc aggaatcggt ttttatttga aacagtcagg aatagttgat
     1021 caatttttta aatcatagga ggaaacaaag atggaaaaca aaaacatgaa tacaacaaat
     1081 ggatcagttt tggcaaatga aaaaggagaa aaccgcatga tgaatggtga attgacttat
     1141 gaagacaaag tcatccaaaa aatcatcggt tatgcattga aagatgtaga tggtctattg
     1201 acattagatg gcggattttt ctcaaatatg gctgaaaaat tagtcaacac agataacgta
     1261 acagcaggta tcaatacaga agtaggtaag aaacaagtag ctgtggatct agatgtgatc
     1321 gtagaatacg gtaaagacat cgaagatatt tacaaccaaa tcaaagaatt gatcagtact
     1381 gaagtaaaca atatgacaca tttagatgtt atcgaagtga atgtgaatgt tgcagacatc
     1441 aaaacacaag aagaatacca aaaagatcaa gaaacagtac aagacaaagt aacagaagca
     1501 gcaaaatcca caggacaatt tgcttcacgc caaacagata aagcaaaatc tgctgtaggc
     1561 aaaggtgcac aaaaagtcaa agaaaataac gaaccacgtg tacaataaga agtaagaagt
     1621 cagttaggag gaatttaaaa tgggatttat ttgggcatta atcgtcggcg gtatcattgg
     1681 agcaattgca ggagcaatca cgaataaagg atcatcaatg gggatcatcg caaacatcat
     1741 tgctggttta gtaggttcag caattggaca agctttacta ggaacttggg gaccaacaat
     1801 tgcaggaatg gctatcattc catcattgat cggtgcaatc attttagtat tagtcgtttc
     1861 attctttgca cgtaaattat aagcaaattg aagaaaaact tatgttgaaa tgaagaacaa
     1921 atttgagaac cgtagcgaca ctcgctgcgg ttctttttta tatattttat atgaagtatt
     1981 ctttattcct tatgaaaaaa tatctttaaa aataaaaaaa gacgaaaata aacggttttc
     2041 tataaaaaga agaccgttta ttttttgtct ttatttgtgt gaaaaacgaa aaagagcaca
     2101 acacatcaag cttttattaa ttgtctgtct tttataaatg caagtattaa ttcaaaaaaa
     2161 cagaagaaaa aaacaactac accttctttt atactcgtaa tcgtagaaag gaggcgaaaa
     2221 aaatgaatac attacctatc aatacaggag atacagcatt catgatttta tgtacagcaa
     2281 tggtttgcct gatgactcct ggtctagctt ttttttacgg cggattagca cggaagaata
     2341 atatactaac gatcatgtct caatcttttc tctccgttgg gataacaacg attatgtggg
     2401 tatttggtgg attcggattg gcctttggac gggatatcgg cggtgttatt ggaaacccgg
     2461 cagatttctt tttgatgaga catgttacaa gcttccccaa catgtttcat ggtgcaacga
     2521 ttccattttt aatgttcttt ctttaccaac tgatgtttat cgtgattacc gttcctttga
     2581 tgacaggagc ttttgcaggg agattgaatt taaaaggcta tattatactt gttatttttt
     2641 ggaatctgct gatttatttc cctgtttgcc actggatatg gggtggcgga tttttggatc
     2701 agatgggatt tagagatttc gctggtggag cagtcatcca cacgacagct ggattcggct
     2761 ctttagcatg tatcctcaca cttggtcaaa gaaagattcc tttaggagaa agaagtcagc
     2821 atagcagtct tatggcagct gctatcggta caggactgct ttggtttggc tggttcggtt
     2881 ttaattccgg tggtgcactt cgagcagatg aacaagcagt caatgcattt ggttcaacat
     2941 tcatcgctct tgcatttgcg atgattactt ggctgatcat tgcaaaagta aaaggaaatg
     3001 gctttgattt tgtcgacgta ctaacaggat ccgttgctgg attggcagcc attacgcctt
     3061 gtgccggtta tgtagaagca aaaagtgcca tgctgattgg gatcattgcg ggtatcgtct
     3121 gtcatgctgc tgttgatttt cgtaaaaaga aacaatggga tgatgcactt gatgtgtggg
     3181 gtgttcatgg catgggcgga ttcacaggta cgattctgat agggatcttt gcatctaaca
     3241 gccatttact aacgaatcca agcagctggt acttcttagg gattcaagtg attggtgtca
     3301 tcattactgc cgtgtatgcc tatgtgctga caacagtgat tttaaaatcg gcgatgcact
     3361 ttacaacgat cactactaca aaagaagaac aagaagaagg attggacttt ttcttctttg
     3421 gcaacaaact caattgaaac aaattcaaat agaaaagagg aagattcatg caacaaagca
     3481 aaacgaaaat tcctgcaaaa aaattaacgt tctttggctt tttggctatg accatctcaa
     3541 tggtcgtttc attatatgaa tatcccacat tcgcgacctc aggcttcagc ttagtatttt
     3601 tcttgttatt aggcggtttg ctatggttta tccctgtggc attgtgcgca gcagagatgg
     3661 caacggtgaa aggatgggaa aaaggcggtg tctatacttg ggtcagtcgc acattgggaa
     3721 aacgattcgg ttttgccgca atctttttcc aatggtttga gataacagtt ggctacttga
     3781 ccatgctgta tttcttaact ggtgcattat cctatgcaac gggtattggt gctatacaaa
     3841 acaataaata tctgaaattg gcaatcctat tgattatttt ctgggctatt ttactctcac
     3901 agttaaaagg aaccaaatac acttcattga ttgctcggat cggttttgta gctggtatct
     3961 tgttgccagc attagtcttg tttggcttag ggatccatta tgtcgcttca ggcgctccac
     4021 tacaaacgat actgtctatg aaaacattga ttcctgattt ttcgaaattg cctacgctgg
     4081 ttgtttttgt ttcctttatt ttagcatata tgggcgtaga aacatctgcc agtcatgcaa
     4141 atgaaatgga aaaccctaaa aaggattatc cattagcaat gtttgtattg gttattctgg
     4201 caatcatttt agatactttt ggcggattga ccgtcgctac tacagtacct caacatggtt
     4261 tgtctcttaa tacaggggtg attcaatcgt tagaattcct attaagacac attgatccaa
     4321 atcttgcatg gattgcgaaa attcttgcga ttcttgtttg tttaggtgtc atcggagaaa
     4381 ttgcttcttg ggtaacctct ccttcaaaag cacttcacgt agcagcagaa gaaggattac
     4441 ttcctgaata ttttgcaaaa gaaaacacac acggtgttcc tgctcatttg atgatcgcaa
     4501 atgggatcgt tgcaacaatc tgggcagccg tctttacatt aagcggcggg gggaataatc
     4561 tttcatttct tgcagcgatg tcattgactg ttgtaatcta cctgatgttg tactttatgt
     4621 ttttcgcggg ctatttgaag ctggttttta aagatgacag tcttgaaaga gcctatcagg
     4681 ttccaggcgg aaaagttgta aaagtaatcg ttgcttgttt aggtcttttg acttcacttt
     4741 ttgctttttg tatctcattt gttccacctg ctagtatcgc agctggacag catgggattt
     4801 atgaaacgat tctgattgtt tcttatctta tcgtcttagt tattccattt acgatctacg
     4861 catgccgtca taaattccag catgcagaaa aataaaaaat gaaagctggt tattcaaatg
     4921 gaagtaaaag aattagaaca attgattgga aaaaatttcc actattatca aacaggacaa
     4981 gtggcggatt acattccagc attagctgaa gtggatccca aacaattagg tatggcgatt
     5041 tatgatttgg atacaaaaca actgattgag ggaggagacg ccgatgtgcg ctttgccatc
     5101 gaaagcatgt caaaagttcc cgtattgtta ttagcaatca aagacaacgg aatagaaaaa
     5161 gtctttcaaa caatcaacac ggaaccaacc ggttttgcct tcaattctat catgaatatg
     5221 gaaatcaatc atcgcaaaca tccaatgaat ccttttgtta atgcaggagc gattgcaaca
     5281 acctcgttga ttgccggtaa agatgcagat gaaaaatttg agcgaatctt gtcatttatg
     5341 aaagagatct gtgatgatcc taatatcaca ttgaatgaag aaatctatca ttctgaatca
     5401 agaacaggtg atatcaatcg ctctcttgct tactatatga aaggtaatca aatgatcgaa
     5461 ggagacgtac cggagatact cgatgcttat ttcagacaat gctccctcaa tgtcaccgct
     5521 acaggcatag caaaattagc tgctgtgctg gcaaataaag gaattgctcc ttggaatggc
     5581 aaacaaatca ttactgaaga aagtgctaca atcgtcaaat caattatgac aactgctggt
     5641 ttgtatgatg aatcaggaga gttttccgtc catgttggtg tacctgcaaa aagcggtgta
     5701 ggcggcgggt tgatggcagc tgtgccaaat cgttacggca taggtgtctt cagcccggca
     5761 ctagatccat ttggtaacag cgcagctggt atccaattgt tgaaagatgt agtcaaagaa
     5821 ctagacgctg acatctttga ataaccattc ttgaaagagg ctggggtaaa agtccaaacg
     5881 gctcaaagct acctacaatg aggctgaaat tgtgagcttg tttgactttt gtcccagttt
     5941 ctttttttat tggtttttga aagggctttt ctaaataaaa aggaaacaaa aatacgattt
     6001 acagatatga ttaaataaaa tcataagaaa aactggaggc gtgtatcagg aatgctggaa
     6061 aattacatcg agcgaaatat atttagaaaa gtgtatctgt gtgaacaatt atttgaattc
     6121 caagaaatag acatcgaaca aacagctatt tctctaaggg tgactacacc aacgatcctt
     6181 cacgatctag aaagtctagc cgagtgtcta gaatattgta taaaagaaca agtaagagag
     6241 aagcataagt ataaactcgt attcaaacat ggtattgctc tttctgagct cacacagttt
     6301 ctgtacggtc aatcttattt tttaaagttt ttaagttatt attttaatgg tatattcacg
     6361 agtacagaac tggctgatct tgaatttatt tctttgagca aagtatatac aatcaaaaaa
     6421 atcgtattgg atttttttaa agaaaatgat tatttgaaaa ataaagaaat cattatccca
     6481 gaatttgact cgcggaacat cttgctagct ttagtacgtt atgtcaattg ggaaggctat
     6541 gaaaataaaa atccgtatgt agaagaagct tgtaacgagt tgattgatta tgtagagact
     6601 cattttttta aaagaagata ttcggaagat gaaaagtcct ttatcatacg aggaatagag
     6661 atcgcaatcg gaagaaaggc atttcccctt ggactgaaag aagaagataa gaaaagcgca
     6721 gaaacgaagc cgttatttca attagtctgt caaggattgg aagagcaaaa aggaattcta
     6781 gacttacaag aagaagatgt ctattatatt ttttctttgt tcaacagtag aaattatacc
     6841 aatgagaaca tggagctgtt aagaaaagat ttcgaagttg tttataaaaa ttttgttctc
     6901 aatgacctat cactgaatga attgatttta cagattatta gtatcgctga aatcgacgat
     6961 gcagaaaatt ttattttcaa gcaatccttt ttacaatttg tccgtacgtt gtgggcagat
     7021 ggacaagtat ttttaccgga aaggatctat cttctatcag aaaaagaaca acttctgtac
     7081 ggaaaaattg tagaaatatt ggaagagtgg aaaaagaaaa atcaaatcca actaagatgg
     7141 aatgaaaatt tcattcgaaa attcgtcaaa agtctttctt tgatcaacag tgaacaagcg
     7201 gggagacagg aaatagaaat ttttgttgtt tcagaaagtt cagtcaaaca atttttttat
     7261 cgaacccaat ttcatttgta tgcggaagaa ggcatcgctg aaataaatcc tattttattt
     7321 cgttcattag aagaattgcc tgatgaatgt ctatgtgcga aaaaaagagt ggttttgtgc
     7381 gatgctgcta gctatcaaaa tggattagaa actgaaaaga caaagatcta tccaatctca
     7441 ttaaaaggtg caaacatcca tttgtatcat attgctcagg aacttcacct attaaaaaaa
     7501 catatttctt gatgagacct taattaggag accttctaca aagcttttta attgtctgta
     7561 gaaggttttt atttgagtcc tgattcgtgc gaagatctac ttatataaca agctttctct
     7621 gaaatttttt taaaatgcta ttgacttaga gtcaactcta agtagtagaa tagataaagt
     7681 gtaacaaatc tattttcatt aaaagaagat agtacggagg agagaatgta ttatgagtac
     7741 agtattacat gtattggatg caatcaatag ccccgcagat gtcaaaaaat tatctgttga
     7801 ggaaatgaaa cagttggcag aagagatgcg ccaaaaaatc ttgcaaaagg acagcgatgt
     7861 aggtgggcac gttggtccga atctaggtgt agtagaatta acgattgcgt ttcattatgt
     7921 atttgattca ccaaaggata aaatcgtttg ggatgtttcc catcagtctt atggtcataa
     7981 gcttttaact ggtcgaaaaa atggttttga aaaaggacat taccgtgaag tgagcggata
     8041 ttccaaccaa catgaaagta aacatgacta ttttacagtg gggcacacat ctacatctat
     8101 cagcttagca acaggtttag ctaaagcgag agatctgaag aaagaatcag gaaatgtggt
     8161 agcatttatc ggtgacggct ccctaagtgg tggcttagct tttgaaggat tgaacaatgg
     8221 tggtgtttta caatccaatc taatcgtatt agtaaacgat aatgagatgt ctattgatga
     8281 gaatcatggc agtttatata aaaacttagc tgagcttcgt caaaccaacg gtaaaagcag
     8341 caataaccta tttaaagcaa tgggatttga ttatcgttac gtggataatg gaaacgatct
     8401 ggaaacggtg atccgtttat ttgaagaagt aaaagatatt gatcatccga ttgtacttca
     8461 cgtccatacg gaaaaaggtc gcggttatca gccggcaatc gataataaaa tgaaatatca
     8521 ttggcatgta ccatttgatc tgtccaccgg ggaggcaaag caagtaactt ctggagaaac
     8581 atttaatatg atcatcatgg attatttgga taagaaaatg caaacaagta cagctcctat
     8641 tgccgcagtc aatgcagcga taccaggcgc ctttggactg aaaacattcc aagaaaaaca
     8701 tccagatcat tattttgacg tggggatcgc tgaacagcac tctatcactt tcgcttctgc
     8761 tttggcttct cagggagtac gtccagtcgt cttccaatca agtactttct tgcaacgggc
     8821 atatgatcaa ttatcacatg atttagcgat caacgagaat ccagtgatta ttttagtcgg
     8881 tggcggaacg atctcagcta gtgaccgaac acaccaagga acatttgaca ttccttactt
     8941 atcaagtatc ccgaacatca aatatcttgc tccagcaaca aaagaggata tgatctctat
     9001 gctagattgg gcgttcgaac aaacagcgca gcctgtagca atccgaattc ctacacatgg
     9061 tgtagaacat ggtacagcta tcgcaaatga ttatagtatt ccagcctatc aaacagtaaa
     9121 taatggagga aaagtagcaa ttttagcttt aggcggtttt cttgaattag gaaaagaaac
     9181 agtaaaagct tttagaaaaa aaggaatcga agcaacgttg atcaatccag gaacgatcac
     9241 agaaaatgac gtagaaacat tagataaatt aaaagaaaca cacgaattag tcatcacatt
     9301 agaagatggt agtttgtcag gaggatttgg cgaaaatatc agtcgttatt atggtgattc
     9361 ttcaatgaac gtattaaatt ttggtgcaga gaaagaattc acggatagcg ttcctgtagg
     9421 gcagctttat gaacgttatc atttaacacc aaaacaaatc gttgaagata gtctgcgtgt
     9481 cttgaatatt caataattca ttatgctcac catccagata attgtttata ctagtatctg
     9541 gatggttttt tcattataaa aagcaaaggg gtggatgtta tgtatcagca agtagaagaa
     9601 tatgtcaaaa agttccaaga aaaatatcct agttatcaat cagaaaaatt aggtttcttt
     9661 tcatttgggg atacagaaaa aatggcagac gagttgagcg aactagttgt aaaaaagata
     9721 aagactggta catcaagtgg ttacgatctg tataaacaag agaatgagcc tttaccaaaa
     9781 gttggtcaat tagacgtggt cctgaatgga aaaaatgaac cagtttgtat catcaaaaat
     9841 ataaatgtga ccatcttgcc ttttagtgaa gtcacgaaag agcatgcttg gaaagaagga
     9901 gaaggggatc ggacattagc ttattggcgg aaagtccatg ctgagttttt taaacatgct
     9961 tataaagaag cgttgaacat agaatttaca gaagagaagc tggtcgtata cgaagaattt
    10021 gaagtaattt tcttttagta agaaaggtct gctgaaagaa atagctcatt attgtctcct
    10081 gaatagaaaa gggttacatt tttatatgaa gctgtatttt tatataacat tactggagga
    10141 gatattgtgg atacactgga acaaatcaaa ggcggagtcg tcgtttcttg tcaagctttg
    10201 gaaaacgagc cgctacacag ttcttttatt atggggagaa tggctttggc tgcaaaagaa
    10261 ggcggagcag ttggtattcg agcaaatacg acagaagata tcaatgaaat caagcgaatc
    10321 gttgatttac cggtaatagg gattatcaaa agagattacg atgggtcaga agtgtttatt
    10381 actgcgacag aaaaagaagt ggaagaactt ttggagacgc aagcagaaat cattgcactg
    10441 gatgcaactt ctcgtaaacg tccgacagaa aaaacaactg ctgaacttgt ccaaatgatt
    10501 cacgaacacg gtcggttagc tatggcagat atttcgactt ttgaggaagc gcttcaagcg
    10561 caagaagatg gttttgatct tttgtctacg actttagcag gctatacaga atattcacga
    10621 aagacgcaga cacctgattt tgatttattg aatcaaatca tagaacaagt cgatatccca
    10681 gtaattatgg aaggacatac tgactctcct gaacaagtag agaaagcata tgaattaggt
    10741 gctttttcag tcgtagttgg atctattatc acccgtccgc aattgatcac taaaagatat
    10801 gtcgaagccg caagtaaagc aaataactaa aaaacacgca cggcacagat tcttgacaaa
    10861 aaagaaaaat tgatagatag tttaaagcag attctaagaa gatgaaaaaa gcattacttt
    10921 tcattttgtc ttcaagatct gctttttaac gaattttata gaaagaaggc gaaaccatgt
    10981 ttgaacggag tccttcagaa ttgacagaac gtgaaaatta caagttgctg attggttcag
    11041 tcatccctag accagtagca gtagtaacga ctaaatcagc aaaagatata gtgaatatcg
    11101 cacccttcag ttacttcaat atcgtcagtt cgaatcgacc catcttatcc ttggcgatcc
    11161 agagaaaaca agatgcagta aaagacacag caaagaatat tcttgagaca agagaagctg
    11221 ttatccatat ccttgatgag gacaacgtag aagaagtaaa taaaacagca gccaatctgc
    11281 ctaatgagga aagcgaactg tacctgactg acttgacttt aactgattca gtaatcattt
    11341 cagtaccagc attgacagaa gcaaaagttc gttttgaaac atccttatat gaacatgtcg
    11401 agatacggaa taaaaataaa gtaacagctg atttattttt gctagaagta cagaaatatc
    11461 atttaaatga aacagtctat gatgataaga caggaaggat cgatccaaga aaattgaatg
    11521 ctgtaagccg tttggcagga aatgattatg cagcaatagg agaaattttc acgattgcac
    11581 gtcccgaata aaaaggagca ctagttatgt taaaaataag ctataaacca tcgacagatt
    11641 caaaagaaat gaaaaaagaa tatgaaacag tgaatgattt tctgcaaggg cagtacttag
    11701 aagttccgcc attgcaagac cattttgtcg ttactactgt tactttagat ggtaaggaaa
    11761 tagaaatgcc agatcaaacg attagcggat tgtttaatta ctttaacaaa taaatattta
    11821 ttccgaaaag tgaaaaaaca tataaaaaaa cacataaaac taaaaaatta tcaaagaatc
    11881 ctggtgcaac tgaaagaatt tgcaacggga ttctttcaac ttatttgtta tttttttcta
    11941 aaaaatatta aagattgtta aatttcacta tttcatttca aattccattg cctaatcatt
    12001 aggaaaagtc tatcatgaac tcgtaaatag aatatagtaa taaccttgtt aggtgaggct
    12061 cctatacaaa cataggctgt tgcccagaaa cgtcgaaagt cgccaatggg taaaacagaa
    12121 actgttggat taaggctttt tccaatagct aagaatgttt tctttacgtt gtatagtgct
    12181 aaaactcgga cgatgagatg atgctaggtc agaattcttg ttcgaaaagg tttctgacct
    12241 tttctttata tttttgtgac tgacttattt gatgagacaa actcgctcct cacctgacaa
    12301 gtggattgct gtgtgaggag gagatgcggt gaaaaaagat cgattggtgg attttgggtc
    12361 cttatttgac tttgtccatg atcggtcttt tagaagtata cagtgccagt tcttatcgtt
    12421 tattgcaagc cgatgaaaat acaaaaagtc tattattgcg tcaactaatt ttcatatttt
    12481 tgagttggag cgtgatcttc ttagctcgtt cagtcaaact acactattta cttcacccta
    12541 aaatagcagg atacggttta gccttatcga ttttcttttt agtattagta agaataggga
    12601 tattcggtgt cactgtcaac ggcgcacaac gttggatctc tctgtttggc attcaattcc
    12661 agccttctga actggcaaat ctttttttga ttttttattt aagctggttt tttcgtgacg
    12721 gaaatagtag cccaaaagat ctaaaaaaac cattcctgat tacagtaggt ataacttttc
    12781 tgattttatt tcagccaaag attgctggag cattgatgat cctttcgatt gcgtgggtca
    12841 tattttgggc agcggcggtt ccatttaaaa aagggatcta tctaatcgtt actttttctg
    12901 cattgctgat tggagcagca ggcggggtat tatatttagg aaataaaggt tggcttccac
    12961 agatgtttaa tcatgcttat gaaaggatcg cgactttaag agattctttt atcgatagtc
    13021 atggtgcggg ctatcaaatg acccattcgt tttatgcact atataatggt ggcatatttg
    13081 ggcggggatt aggaaatagt atcacaaaaa aagggtatct tccagagaca gaaacagatt
    13141 ttattttttc gattattaca gaagagcttg ggctaatcgg tgcattgtgt gtgcttttct
    13201 tattgttctc attatgcatg agaatctttt gtttaagcag tcgctgtaaa aatcagcaag
    13261 ctggattgtt tcttttagga ttcggaactt tgctattcgt tcagacgata atgaacgtgg
    13321 gaagtatcgc ggggctgatg ccaatgactg gtgtgccatt gccatttgtt agctacggag
    13381 gaacaagtta tctgatcctt tctttaggaa tcggaatcac gttgaatatt tcttcaaaga
    13441 tacaggccga agagttggcg ctctatcgac ctgaaaaaca ataaagagaa actgagaaac
    13501 tctcagtttg aattatcata aagtacaatc ttttattttt caagcgagag gttcttttag
    13561 aaagaggaat tcgcaatgaa agtatctcaa aaaatcatat tatctatttt gttactgctt
    13621 acattagtag ttggctattt ttcgattgag tttatccatg gattttcgtc tgcaaaacag
    13681 agttcaactg tgaaaaaggt agagccgaaa agtatcccta ccacactaaa tgtggctttg
    13741 attggttcag atgctcgttc gaaagacgaa aacggtcgct cggattcact tctggttgca
    13801 caatacaacc agaaaacaca acaagcaaaa ctgatctcta tcatgagaga ttcatatgtc
    13861 gatattccag gttacggaat gaataagata aatgcagctt actcttatgg gggagttgat
    13921 ttattaaatc aaacattaaa ggaaaatttc aaatttgaag ctccctatta tgcaagtatc
    13981 acatttcaag attttatcga ttgcgttaat gaactgtttc ctggtggagt caagatcgat
    14041 gcagaaaaat ctctagattt agatggcgta tatataaaca aaggagagca agtgatggat
    14101 ggtaatactt tactccagta tgctcgattt cgggaagaca aagaaggaga cttcgggagg
    14161 atcagaaggc agcagcaagt gatcaaagct atctctcagc agctgaaaga cgtaacttca
    14221 atattcaagc tacccaaagc ggttgggaaa ttacttggta gtatccaaac gaaccttcca
    14281 gaaagtgtgc ttctggattg tggtatggat ttcctcaaag acatatgtta gaataaacag
    14341 gtataaatag tgaaataaag gaatgacaag caagagaagg aggaaaaaat gaaaagaagt
    14401 gacaagcacg gcaaaaatcg aacaggcgct tatattgccg gcgcagtgat cttaatagca
    14461 gctgcgggtg gcggttattt ttactaccag cactatcaag aaacccaagc agtagaagct
    14521 ggagaaaaga cagttgagca atttgtccaa gctttgaaca agggagatta taacaaagct
    14581 gcagaaatga catcaaaaaa ggcggcaaat aaaagtgcat tatctgaaaa agagatctta
    14641 gataaatacc agaatatata cggtgctgct gatgtcaaag gacttcagat atcgaatcta
    14701 aaagtagata aaaaagacga ttctacttac agtttttcat ataaagcaaa gatgaatacc
    14761 tcattaggtg aattgaaaga tctttcttat aaaggaacat tagacagaaa tgatggtcaa
    14821 accacgatca actggcaacc caacttggtt tttccagaaa tggaaggaaa tgacaaagta
    14881 agcctgacca cacaagaagc agcaagaggg aatattatag atcgaaatgg tgaaccatta
    14941 gcaacaacag gcaaactaaa acaattagga gtcgttccaa gtaaacttgg agatggaggc
    15001 gaaaaaacag ccaatatcaa agcgattgct tcctccttcg acttaacaga agatgctatc
    15061 aatcaggcga tttcacaaag ctgggtacaa cccgattact ttgtcccatt gaaaatcatt
    15121 gatggagcaa cgccagaact tccagctgga gctaccattc aagaagtaga cggcagatat
    15181 tatcctttgg gtgaagcagc tgctcagctg attggttacg tgggagatat cacagcagaa
    15241 gatattgata agaatccaga attaagcagt aatggaaaaa tcggtcgctc aggtttggag
    15301 atggcttttg ataaggatct tcgtgggaca acaggtggga aattaagcat tacagatgca
    15361 gacggtgtag agaaaaaagt tctgatcgaa catgaagttc aaaatggcaa agatatcaaa
    15421 ttgacaatcg atgcgaaggc acaaaaaaca gcttttgaca gtctaggagg aaaagctgga
    15481 tcaactgttg cgacaacgcc aaaaaccggt gatcttcttg cgcttgctag ctctccaagc
    15541 tatgatccaa acaaaatgac aaacgggatc tcacaagaag attacaaagc ttatgaagaa
    15601 aatcctgaac atccattcat cagccgattt gcgacaggtt atgctcctgg atctacgttt
    15661 aaaatgatta cagcagcaat cggtctcgac aacggcacta tcgatccaaa tgaagtgttg
    15721 acgatcaacg ggcttaaatg gcaaaaagac agttcttggg gatcttatca agcaacgcgt
    15781 gtcagtagtg atgtatcaca agtagactta aaaactgctt tgatctattc cgataatata
    15841 tatgcggcac aagaaacgtt gaaaatgggt gagaaaaaat ttcgtacagg cttagataaa
    15901 ttcatttttg gtgaagacct tgatttgcca attagtatga atccagcaca aatttctaat
    15961 gaagatagct ttaactcaga tatcttgcta gctgatactg gatatggaca gggcgaactt
    16021 ctaattactc ctatccagca agcagcaatg tattctgttt ttaccaacaa tggcacactt
    16081 gtctatccta aattgattgc agataaagag acaaaagata agaagaatgt catcagcgaa
    16141 acagcagtac aaacgatcgt gccagatctg agagaagttg tgcaagatgt aaatggtaca
    16201 gcacattctc tttctgcttt agggattccg ttggcagcga aaactggtac agcggaaatc
    16261 aaagaaaaac aggatgtaaa ggggcaagag aacagtttct tgtttgcttt caatcttgat
    16321 aaccaaggtt atatgatggt cagcatgttg gaaaataaag aagatgatga ttcagcaacc
    16381 aaacgagcat cggaactatt gcaatacctc aaccaaaatt atcaataaaa aattgctttt
    16441 taagtacagt aaaaggactg tggcgttatc gtcacagtcc ttttttcaaa taaacggttt
    16501 tcacgatgtc tctttcacaa cttctttttg atttactcac acttcataaa ctttttttgt
    16561 aaaatatttg agaacaagtg gagaaataag tgtacttaat aaaatcacga taactaaagg
    16621 tgaatagtac tgtggttcga tcaattgact ttgctgtcca atttgtaaaa tgatcaaagc
    16681 catttctcca cgcgaaatca taccagcacc gaccatcaat gaactatgtt gagaaaaacc
    16741 ggcaatctga gcaccaaaat aacctccaag caatttggtc aaaatcgcta caagcgtcaa
    16801 tatagaaata aagagtagtt gttcactaaa gtcagaaaaa tcaacttcta atcctacact
    16861 gacaaaaaat actggtataa atactgcata tcctaaagcc tctacattgt ggtatacttc
    16921 ttctttaacc tttgtctgac tgacagctat cccagcaaaa aaagcaccaa tgacagagct
    16981 aagcccaaca agatccgcta cgtaagacat tcctaaacaa ataactagcg atacgatgat
    17041 aatagaagaa tttgcgtaca ctttttctgc aaatgaaagt aggaaaggcg caatccattt
    17101 gactaataag aaaataaaaa caaaataaat tagctgttca atcaaaacaa gcggtaaaga
    17161 agcattgcta gaagcttccc ccgttagaaa agataggctg aaacttagaa ctaaaacgac
    17221 taaaatgtca tctaccacag aagcacccaa aattgttgat ccttcttttg tattcactac
    17281 gtttagttct tttaatactt ctactgaaat actgacagaa gttgccgcaa gaataatccc
    17341 aaagaaaatc gcttcatttc ccgaaacttg gaatgctttg cctgtcaacc agccaaaaac
    17401 aaccgggaag atgatcccaa gcaaagcaac gaacatacca ggtcggaaat attttttcaa
    17461 aagagataaa tcactttcca gaccagctaa aaacattaat aagatcacac caatctccga
    17521 aaagtcatgg actagaatat caggtttgac ccaattcaat ccagcttggc ctagcaaaac
    17581 accaacaagt aattgtccaa tcactgctgg gatacctaat ctccgcgaga tatgtgagcc
    17641 aatcgttgtt gaaatcaata tcaggcataa aataccaata aattccattc tcatcattcc
    17701 tttgtataaa atatagcccg aacttagcat aacatacatt attgaaaaaa taggaaaata
    17761 tactcacaaa aaaaccaaca atccaaaaga tttttttgga ttgttggttt ttatacggtc
    17821 tattttaata actaaaaatg attaacgtat agtcattttt cttattctga tgaaattgat
    17881 aatctcctgg atgcccatga aaatcaaaat aaagccgaat atttggaata gaagcatcaa
    17941 acttttgaat ggattgaaca ataagacgaa tccgccaatc aacaacagaa tactactata
    18001 aacactccaa cttttagctt ttgtattcat gctgaagaac aactggaaca agctgttgat
    18061 gataacagct aatccaagaa gaatcggcag gatagaaacg attgcaggtg caaaagcata
    18121 gacgatcaga gctaagatca ggaaaaaaag accactgaac agaccgatac tccaagaacc
    18181 tgttttcctt ttaaaacggt aagcctcaaa aagattcaac aacccaagca aaacaagata
    18241 ggcggtgatc agataaccga taaaatgaaa aacagcagaa gggtttagca caatcgcaat
    18301 cccagaaata atataaacag cagctcttaa taaggcgtat ttttgaatat tttgtttaat
    18361 cgtctcaaac atataagaaa acctcctttg acttatttta acgtgaacta gtcattttac
    18421 caaattaaat gttacaaaat gagcgaagga gaagaatatc tctggaaaaa tcaacttctg
    18481 aggatctttt ccattttttt gccttttgct agctcatcga tcattttatc taaataacga
    18541 atttctttca tcaagttatc ctcgatgtct tctactcgta caccacaaac aacacctgta
    18601 atcaaggaac gtgaaggatt ggggacaggg gcttccgcaa aaaattgttc gaaagtcact
    18661 tgtttttgta gttgatattc tagttctgtt tgggaataac ccgtcagcca acaaatgatt
    18721 tcatctactt cctcttttat acgatctttt ctctccgctt ttgctacata cataggataa
    18781 acgcttgcaa aacttgtcgt aaaaatacga ttttgcgcca taatcagtca cctttctttt
    18841 tttcaaatta tttactactt atagtatata agaaaaagag aagaaaaagc gattattcaa
    18901 aaaaacaaaa aggattgtga caaaattctt gtcaccatcc ttttttccgc tctctgactt
    18961 tttacaatct tcatagctca agtgcgcatc agataatcga atgctcctaa agctgcagta
    19021 gctcctgaac ccattgaaac aatgatttgt ttgtatggac tatctgtaca atcaccagct
    19081 gcgaaaacgc cggggatatt cgttgcgcca tttttctcgg tcactatttc atttcttgga
    19141 ttcatttcga tcgttccatc tagccaatcc gtattaggga gtaagccgac tagaatgaat
    19201 actcctgaaa cagctagtgt atgcatctcc atcgtacggc gatcgatata ggagagagat
    19261 tctacctgat tcgtaccgct gatttctttc gtcgctgcat gtttgataac agtgacattc
    19321 gcaagagaga ctagtttatc ctgtaagatt tgatctgctt ttaattctgg taagaattct
    19381 agaacatata catgttttgc taacccagcc aaatcgattg ctgcttcaac accagaatta
    19441 ccaccaccga taacagcaat ctcttttcct ttaaataaag ggccgtcaca gtgtgggcaa
    19501 taagcaattc ctttattttt aaactctttt tcgcctggta cattgataga acgccagtgc
    19561 gcacctgtcg cgatgatggc ggtttttgct ttaagtgata taccgttagc taagccaata
    19621 ttaataaaat gttgctcttt atttaaggaa acggcctgtt gattcatcat aatgtcgata
    19681 gggtaactac gcacatgact ttctacttgc tgcatcaatt ttggaccttc tgtgtaagag
    19741 gtaccaatca tattttcaat ccctagtgtt tcaacgactt gtccgccgaa agaatcagcg
    19801 acaagtcctg tacggattcc tttacgtgct gcatagatag ctgcactact agctgctggt
    19861 ccaccgccaa tcactaatac atcataaggt tctttttcaa acaactcttc ttcaatcaaa
    19921 gggccagtga ttttttcaac aatttgttcg atcgtcatgc gtccgctact aaattcttct
    19981 ccatttaaaa acacagttgg cactgccatg atttttttat catcgatttc tttttggaac
    20041 atcccacctt caatcatcgt atgagtaata tttggattta atacagctaa tatattcaat
    20101 gcctgtacaa cgtcggggca attatgacaa gtcaagctaa cataactgtc aaaatgcaat
    20161 gtttgtgtta tttttttgat tttaagactc aaagattcac tgattttcgg tgcccgtcca
    20221 ctaatttgta acatagccag taaaaaagag gaaaattcat gaccgagggg gataccagca
    20281 aaaacgattc cactttcttt gccaactgga ttgatagaaa aactaggtgt gcgcatcgaa
    20341 tctctttttt cccaagagat tttaggagac atttctgcta tttccttcgt aaattcagct
    20401 agtttttgac tattttcact attatccaaa ctaacagaaa aaacaatagg agattcaatc
    20461 agtgctaaat attgttcgag attttgttta gtttctttgt ctaacatatc caccacctaa
    20521 atctttccaa caagatcaaa acttggtttc aatgtttcgc cactttcttt ccattttgcc
    20581 ggacaaactt cacctgggtg ggtacgtaca tattgagcag cgcgaatctt atcaatcagt
    20641 gcactagcgt cacgaccgat tccatctgca ttgatttcca tagcttgaac gattccgtct
    20701 ggatcaataa taaatgttcc tcgctgagct aatccttgct cttcatccaa aacatcaaaa
    20761 atacgagaaa tctgatgaga cggatcaccg atcatcacgt attcgatttt accgatagca
    20821 tctgatgtat catgccatgc tttgtgagta aagtgggtat cggtagagca agaaaagact
    20881 tcaacaccta aagatttcaa tgtactgtat tgttcttgta agtcttctaa ttcagtagga
    20941 caaacaaaag taaaatcagc tggatagaag caaagaatac tccagttccc cataagatct
    21001 ttttcactga cttctaaaaa ttctccttga tgataagcat gtgcattaaa ttcttcgatt
    21061 tttttcccaa tcaatgacat agtaaaacct ccaataataa ttatttattt ataattattg
    21121 taatttagtt ggagttgcaa agtcaatgga tattttgtta tttaataaag attactcaaa
    21181 aacgaaggtt aattataaaa atagaagagg tcgcaagaaa atgctactgc tggaaatact
    21241 cgggataacg ttgagtaaca gtttcctgtt ctttcagcat catgtgtaag tgcaatcccg
    21301 tttgaaatcg agcttcttct ggttttttat caactaaagc cttgagtaaa tcataatgtt
    21361 gttccatgat cgtttcccat ggaagcccct gaatggtcac tcgtaaccag cggaaacgtt
    21421 ctaaatgggt attatggtca tctaaccagt tccaaacttc ttttcttcct gcaatttcga
    21481 aacaagcttc atgaaataaa ttatctgcac ggaaaaaagc gcgttcgtca tttattttga
    21541 ctgctttttc ttgttcttct aaaatcgttt ctagcactat tcgtgtttgt gtgtccaatt
    21601 tggaacaaca ttcaatcatg atttgctctt ccaactgttc tcggacaaag cgagcatttt
    21661 ctgcagaaac aagattaatt tttgaaacat acgtaccact ttgaggtatc gtatacacga
    21721 gttcttgctg acgtagttga atcaatgctt cgcgaatggg agtccggccg atagcaagat
    21781 gttcctccag tgccttttca gatattttcc ttccaggttc taagtcagca tagataattt
    21841 gtttacgaat cgcttgataa gcttgagatt gcaagctgct tttcatcttt attcctccaa
    21901 aatcatttct atgaacgtag tataacagaa gaggtctgaa aaacaatctg gtatgtcaca
    21961 ttaactagta aatttgtata aatagtaaaa ttttggttga catagcgatt tttattgcat
    22021 aaaattcact tgaatacaaa aactaatatg ttagtttagg aggggaaaaa tgattgattt
    22081 aaacaactgg aggaacttta tccctgaatt atctcaaaaa gaagtagaaa tacctcattt
    22141 tgaccgtgca tcattaagag aaaatggaca aaaaaatcct gtctggatcc atttcggtgg
    22201 cggaaatctt tatcgaggat ttcatgcaga aatcgctcaa cgtttagcgg atctaggcga
    22261 attgtccact ggtgtcattg tttgtgaaac attcgatgaa gaaataattg aaagggctta
    22321 ccaagatttt gatgatttga ttcttgaagt ggtcatgcca agcagtggag agttcgtcaa
    22381 acgtatatta gctgcgacag ctgacagtct gtattgtcat ccagattgtt ctgaacactt
    22441 tgataagatg attcgacact ttgaaaatcc tagtttacaa ttagttactt ttgctattac
    22501 tgaaaaaggt tatcgattga aagatacaaa taataaatat ataggaccga ttgcagtcga
    22561 tataaaaaat ggtccaaaga agccatcaca tacaatgagt attcttgctg cgctacttta
    22621 taaacgtttt ttatctggag cttggccgat tgcacttgtc tctacagata atttttcaca
    22681 aaacggtagt caattacgta cttctttgct aacgatcgca aaagaatggc aaaaggaagg
    22741 ttatgtacaa aatacattta tccaatactt atcgaatgaa gaaattgttg cgtttccatg
    22801 gacgatgatt gatcgtatca ccccgaatcc ttccttgtca gttagcaaaa tgttggcaaa
    22861 agagggcttt tcaaatatgt cgattttcca aaccgcaaaa ggaaataata ttgctccatt
    22921 tgtcaataca gaggacatcc attatttaat catggaagat cattttccca atggacgtcc
    22981 gaaattcgaa aaagctggag tattcttgac tgatcgtgca acggtagata aagcagatac
    23041 gatgaaggtg acgacttgcc ttaatccttt gcatacgtct ttagctatta tgggttgttt
    23101 actggggtat aggagcatag ctgaggagat gaaagatcca gatttatcgc tgctagtttc
    23161 tgaaatcggg tacaatgaag gcctcccagt tgtggagtct ccaggtatca ttgatccaaa
    23221 gatctttctg gaagaagtaa ttactgtgcg cttttctaat ccaaatattc ctgatatgcc
    23281 tcagcgaatc gccacggata cctctcaaaa ggtggcgatt cgttatggtg agacgattaa
    23341 aaaatatatg gaaatagaag ttaaagaccc gcagacactt gtattcatac cattgactct
    23401 cgctgcttgg cttcgatacc ttattggcat tgatgatcaa ggaaaaccat tcatcccgag
    23461 tccagaccca ctattgacag actttcagca taagctttcc gatattcaac tgggtacgca
    23521 agatacatca catattcatg agaaaatggc tcctattttg tcaaataaag aaatttttgg
    23581 tgtagatctt taccaagcag agcttggcag aaaaatagaa gaaatgttca tcaagatggt
    23641 agcaggaccg aatgccgtac gaaaaacatt acaggattac ttacaagaac atggaggaaa
    23701 tttatcatgg aaatgacttt tagatggtac ggatcacagg aagaaaagat taccttagat
    23761 gaaatcagac agattcctgc ggtcaaaggg attgtaggca cattgatgga tataccagta
    23821 ggagaggtat ggcctaggga gaggatcaaa gaactaaaag aagaaattga gtctcgtggg
    23881 ttaacactaa aagtaattga aagcgtcaat gtgcatgatg ccattaaaat tggattacct
    23941 tcccgtgagc agtatatcga aaactataag cagacaatcc gaaacttggc agaatatgga
    24001 atagaagtca tctgctataa ttttatgcct gtatttgact gggtgaaatc tgaccttgac
    24061 taccgcttag aagacggctc atccacgtta gcttttatat ctgatgatat tccagatgat
    24121 ccaagagaaa tcgtcgcgcg catcgaacat tccagcaatg aatttgaatt gccgggatgg
    24181 gaacctgagc gcttagctca tatcaaatcc ttgcttgaag cctatgcatc agtagacgaa
    24241 gaaaaacttc gagaaaattt tgcctatttt ctccaatcaa tcatcccaac atgtgaagag
    24301 gtaggggtca aaatggctgt acatccagat gatccgccat actcgatttt tggattacct
    24361 cgaatcgtaa agaatcgaga agatttagat tggttgtgcc gcatagtaga cagcccttat
    24421 aacggaatca ctctttgtac agggagtatt gcagaagatc cagaaaatga tgtatatggg
    24481 attttagcag aattttgtca aagagatcga atcccatttg cacatgttcg aaatattaaa
    24541 tttttagcta atcgagattt ctatgaggca ccgcataaat ccgaatacgg ttcattagac
    24601 atgtaccgca tactaaaaac aatgtatgac aacggattta acggatacat ccgtcctgat
    24661 catggaagaa tgatctggaa tgagacagga agaccaggat acggcttata tgatcgagca
    24721 ttaggtgctg tttatctaaa tggattatgg gaagcaatcg aaaaaggaaa caaaagtaaa
    24781 gataattagt gaaaaaaact gtaattttat tatgtaaata agaaggatgt tcaaattctt
    24841 gatacataaa tccggaggtt gttaataagc attcggattt atgtatctta tttggtctag
    24901 gaagtaactt gattttcttt tttcgattga tccatgagtg cttcttcttt taattcaaag
    24961 atatattctg agatcctcat aatcactttt ttccagtctt ctggtgtgat gattcctttt
    25021 aaaatataga tttttttgat atgagaaggc aattgtttca aagggcagtc gctgataacg
    25081 atgttgcagt tctccataaa atcattttgt attttgatcg attcatttga aaaaatttgt
    25141 tctatcttaa cgatcagatc tttactgata taaaaatcac gcgtatagtt cacaccaatc
    25201 acaattcgcg gctgtttttt gtagcgatca tacaaatgta ctaggtcttc aaccatccat
    25261 tgcacatttt ccttttctaa aataactggt aacaagtgtt gattttgttc tctgaaatcc
    25321 atataaaatt gttcaatggc ggtttggact tctttcaaca cgctatgttc ttgataaagc
    25381 atgaaagtag gaaggggcgt atttggttga ttgaagttaa gaaatccatt ataaagttta
    25441 tttcgtgcga atgccaatga gtaaagaatc ttttcttttt caggtataaa caaatcaaat
    25501 acagtacaaa aggactccac catttctctt gaataaagaa catgaggaac gtttgctttt
    25561 tttaaaagtt tgtattgctc caagcttgtt tcttccgatt cgattttcgt gatagaaagt
    25621 cgagctaaaa tattcactaa gatgcgttgt tcgcgacaaa ttggcagatt aggtcgcaaa
    25681 atatctacag agggatcaat aaaaaagtca atatattcat actctgtgaa ttctttttgt
    25741 acgtctttca cagaagttgc aggaaaattc tctttacata tttttaatag aaaatataat
    25801 ttatctatca taccgctatt tagtcggtca agtacttctt ttttaaaaaa agtattcatc
    25861 ataaaagcca ctacttgcgg atcttcatca taaaattctg tagcagtact tgaaaagatg
    25921 ttccaataaa tatctaatgc tgcatattga atttgtacct cttttccaga aaaagacttt
    25981 ctgccattat tagaaaagga gatagacaaa ccgtacaatg ctaaaaatgc attaatcttt
    26041 ttcattttcg tatacaaata agaggcacta tagtttgttt gctgacttaa actgataatc
    26101 gaatttgtct gacagctgaa caaagaagtc aagatctgat aactgactga ttcgttgcag
    26161 tatcttccaa atagacgata atagcagtaa gccggatcaa ttccttcaaa attcaacttt
    26221 aaaaaaggtt tttgcttatc aatatgcagt tctgttagat tgagacgctc aaagtcttgt
    26281 tctaattctt tgatgtatag taaaaaattt gattcagaca tatggaaatg atctgctaaa
    26341 tattgtgtag taataaagaa acgatgttca gataggaaaa gaaaaatatc taattttgta
    26401 ttgctttttt tcttcaagag aaacgtttta atcgcttctt gagtttgcat gaaagaggct
    26461 cctttttact taaattgtta aaacttgaaa atattactgt ttttttcata aatttagaca
    26521 aaaaaacagt aaacatatag gtagaatctc tactatctta tttcttgcat acaaaaaaat
    26581 caaggagtga gagagttatg agatattcaa ccatcttaat atcaacattt gcagccttaa
    26641 gcttatcgct tactataaat cagacagtcc acacagagga gatagaaaca gccaaatgga
    26701 cagaaaccaa gtgggccaac gtcaatcgaa ttacctttca ggatgaattt tcatccttca
    26761 attcaggagt cgcaaaatta agaaaaggac aaacagcgac catcaaagca aaaattgact
    26821 attcaggaga cttagcacct atactacaat cagctgttac atttgagaat gttgatcccg
    26881 ctttgtcgat tggctatgac gagaacactt tgactatcca acacaagcaa gcgatattta
    26941 ccttcaccgt tacattaaat caggacttgt taaaaccagc gctttttact gtcaaggtat
    27001 cagatggact accgaacgat catcatcatt taacgccgta tagtcagcgg cagacaattg
    27061 agcaagattc agctatcgac tcaggaggag atcttgttga agaaccaaca gataaaccag
    27121 aaaatgaaaa taagccagaa gtaccgccta cagaaaatcc agacggagaa cagaaaccgg
    27181 aaatagaacc tggagaagaa cccgatacag aaactcaacc agagccagac aatgaatcaa
    27241 aacctgaaat aacccctgga gaaaaaccag atgtagaccc agaagaaaaa ccggatgtga
    27301 ctccagaacc agatacggat tctggaaacc aaacagtacc ggaaacaaat ccagacacag
    27361 ataatgaaac tgaaaatcca gaaaaaccag aggtagcccc agaagaaaaa ccagatgtaa
    27421 ctccagaacc agatacggat tctggaaacc aaacagtacc ggaaacaaat ccagacacag
    27481 ataatgaaac tgaaaatcca gaaaaactag aggtagatcc agaagaaaaa ccagatgtga
    27541 ctccagaacc agatacggac gcaagagacc aaggaatacc agaaaaaata aacaaaaaaa
    27601 caattcaaga ggatggaaaa aaagagagta aaaaatcaaa tctagcaatt ctaaaaataa
    27661 atgaagagca gctgaataaa aaatcacgaa tatttgatag cgcccaatca gctgaaacct
    27721 taaaaagtag caaggataca acctttgcta gtcctgaaac gaaaaataaa cagctaccaa
    27781 aatccggaga gtcacaaaac aaagttatac tgtggagcgg aatcattcta ttaagtatag
    27841 caacaatgct ttctgcaaaa agatttaaac aaaacagatc tctctaacat ttgaataatg
    27901 tctgtgaacg catttttcaa ataaaaagaa atatccagaa aacgacccca aaataccaga
    27961 ttgaaatctg atatttgggg tcgttcatac tttatctttc ttcatattta ttttaaggga
    28021 tatctgtttc ttttggaaga tggttcggga tctttttcac tttcaataca tctaaaaaga
    28081 aggtaaagat cggaatgccg acaatcaagc cccaaacgcc aaagaaccgt tcgctaacaa
    28141 gtaagaccac aaatgtataa aaaatcggca gttctgtttt gctggacatc aacttcggat
    28201 tcagcacata agactcaatt agatggacaa tcaaaatcgt aatcaggata taaacaacat
    28261 ctcggatgcc tccttgggaa taagctatga aagatagagg aatacaagaa atgataacac
    28321 ctgctactgg gatcagactt aaaatgaaaa tcatgatcgc taaactcagc agctgatgaa
    28381 agccaaatac agccaaggcg attgtagtga gcaacgtgtt taaaagagcg ataacaaatt
    28441 gagcttctaa taccaaacca aatgtattga caaacttatc ggcaaaatag taaatatctt
    28501 gaaagaacca agaaaattca ctttttaaaa acaatcttga gaatacaatt gtttttttct
    28561 tttcaatcat aaaaaagaaa cttaagatga atgacatagc aaacgccact gccatttttc
    28621 ctatatcctg taaatagcca agcgcaatcg aagcgccatt ttgaagctgt tcaaaaaaat
    28681 cgtttcgctc aatataagta tggatatatt gtaaaacagg atctgcatct tttggctgat
    28741 gctcgtaaaa atcaataacg gactggatca tatcaaatgt ttgatgaata agcatcggga
    28801 tatactttgt gaatgccaga tagataaggt aaacgatcag tgtataaatc atgatagcta
    28861 aaacacctgt agggattcgg acaaatcgct gaatgatttg aacaagatga atcatcaaat
    28921 aagtaaagat aaatgtgagc aaaatggttg taatcatact tctaactaag aaaagaacaa
    28981 aaacgacaaa taataaaaca gtgagacggc gtattttttc attcgccaaa aaacgctgat
    29041 aaacggtcaa atcgacaacc tccaaataac aaaaaataaa cacgttattc attatatgat
    29101 ggaatatgaa aataagaaag agaaagagca aaaagaaaaa ccgctaaatg acgttatctt
    29161 atgagttggt tttcctcata aaatcgttca tctagcagtt tcagcccttt ttctggtctt
    29221 gatgaaaatt atctagcatt tttcgggtca gatgttgcag tgtatccaat tcttcctgtt
    29281 caagtggaag ataagacttg atcttttgtg gaataccttc tgcttgtttt tgcaacgcag
    29341 caccttgagg agtcagcgta acatttacga ttctttcatc acccgtttca cgctgacgat
    29401 taatataatt tttttctgct aactttttta gtaagggagt cagcgtacca gaatccagac
    29461 acaaatcatt tcctagctct ttcactgaag tctttttctt ttcccataaa actaacatca
    29521 caagatactg ggtataggta agattcagcg gcttgaggag ggaagtgtag tgtctaatga
    29581 tttccttaga ggcggcatat aaaggaaaac atacttgatt aactaaatat agatcttcca
    29641 tttttccacc tccgctgttt tactatagtg tatcatagcg gatttacaca aaaaagtcta
    29701 ttcactaact gctttcagag taacttctat atttccagct gtagcttttg aatacggaca
    29761 cactttatgc gctgcctcta ataattcttg cgtttcttcc agagaaagac cttcgataga
    29821 tccttcaatc tctacaccta agacaaagct cgtttcactt tctgaataaa gggaaacttg
    29881 tgcactgaca gtagaagccc cagagatatt tttttgctgt ttgatcaatt ctaatgcact
    29941 gttaaaacat gcactgaaac cagctgcaaa caattgttca gggttggttg cattttcgac
    30001 gcgtttacca ggagctgcaa tattcaattc gaatgtacga tcgggattat gaacttctcc
    30061 agagcgtccg cctgtgttga tcattttcgt agaatacatt tttttcataa aattaccacc
    30121 tttaattata ttttatacaa ttgaatttta cacaatataa ttgtggaaag caaagaaatg
    30181 gattggcata agataaataa gagaaagcac atgaaacaga cgcgctttct cgaatagcaa
    30241 acatatacaa aaaaatatca gagacaaaaa ctaatctcat cataaacatt acatatattt
    30301 ctcaaaaagt tgttttcttt cttcaaaact tacttcacga tggacctgat gaagcatcca
    30361 taaataacca aaaggatctc tgaacattga gttagtcaca ccaaagtcca tcatttctgt
    30421 catttcttga atctctacac agccatttcg taatgcttta ttatgtgtgt cctcgatatc
    30481 agagacgatg atattgaacc agatcgtatt tggatgttca gcagtaggag cagtcaaacc
    30541 aagagacgtg ttttcatcca gcatatggaa tctcgtgcca tacaaggtaa aaatgacttc
    30601 attattgcct ctagggtaat ctgttgcctc aatcagttgt atttcatcaa agattgtttg
    30661 atacagttct agtgctttca aactatcatt taatacaaaa tctatttccg ttcctttatg
    30721 cataaagatc tcctctcctt ttcagtcgaa cagttactag attcttttat tataccagtt
    30781 aaagaaaacg cattcaaaaa aatagcggat ttacttacca actcattcga ttggatgata
    30841 agtaaatccg cgtcccatta cttctgctac gctgctgaca atgacaaagg cacttggatc
    30901 gatttcttct atcaatggtt tcattcggga aaattcatga tcagtcacaa cgatcaataa
    30961 aacctctttt gactttcgat tatacccgcc ttttgcctct agcagggtaa ggccacgtcc
    31021 aatctcagca cttaagcgaa ggcggatgtc ttccaaataa tgttcactca tgaccataac
    31081 agatttcttt cgattgatac ctgtttcgat ataagtcatg acaattgaag tgattgcaat
    31141 agataaaata gcataaagaa actcttctat tccaaaaaca aacagattaa gagaaacaac
    31201 gaatgcgtct gtaaaaaata agccaatcga agtattcaag tggaaatatt ttttaaaaat
    31261 gaggggaggg atcgtcgtac cgccgctaga agagttgttt ttatataaaa tcgcaactcc
    31321 taaagcaaaa atcgcacttc caaaaatgac agacaacaac cgatctgaag taatcattgt
    31381 ttctggaact attgcaatga ttaaaggaaa aaacaagctt ccgaaaagta ctttaaaaaa
    31441 gggtttttta cctaaaaata gaagagctag taccaacata acgatattca acactaaaat
    31501 aactatagct cggtcaaatc ctaaaacagc ttccagtaat attcctagac cgctgacacc
    31561 tccagcagca atatgatgag gccctaaaaa catattgata gcgactccta atatgaagag
    31621 ggcaaaaata atcttaatgt atgtccatat aaattgtctc gtttctttca tttatccact
    31681 tccttaattc attaataata ctcttatctt attataactt acttttcacc ttaagttaac
    31741 tttaattaat aaaaaaatta ggctagtcta aattattatg tttcattctt ctagaatata
    31801 cttctacgtt aaaaactgtt aaaaaacttt tactttagaa aattggagaa attgatcgct
    31861 taagataaat tcaggacact aaatagtaca ggaagtagat taaaactttt aaaagtttta
    31921 agtctatcta tttggcaagt ttaaaaaata aaaattcggt atcaaaaaac tgttaccgat
    31981 aacatttttg aaagcgttgt cttttgtttc tctatcactt atagtgatga cgtcatatta
    32041 aaacacaagg aggaaatcaa tggatacagc tgcaatttat catcgaccgg aaagtgaata
    32101 tgcatttcta tatacgaata caagatttcg tattcggctt cgtactagga aaaatgatat
    32161 caaaaaagta tatgtgcttt gtggagatcc atataccata acaactgaaa aatggtatca
    32221 aaaacaacga ccaatgaaaa aatgtctaag taccaatgtt catgattatt gggaaattga
    32281 agtgacgagc gaaacaaggc gcttacagta tgcgttccat gttgttgggg aagataacac
    32341 ggactgtttt tacggtgatc aaggaatttt tccttatcga gaaaatgtga ttactgaacc
    32401 aaatttttat tttcgaatac cttattttca tcaaatcgat cgattcacta ttccagaatg
    32461 ggtaaaagaa acagtatggt atcaaatttt tcccgaaaga tttgcaaacg gggacaaagc
    32521 aaatgacccc gaacacactt taccttgggg aagtaaagat ccagaccgag aagacttctt
    32581 cgggggagat ttgcaaggtg tgagggatca tttggattac ttgacggacc ttggcgtcaa
    32641 tggcatctat ttttgtccca tatttaaagc cacatccaat cataaatacg atacgattga
    32701 ttattatgag gtggatcccg cttttggcga taaaaaactt ttaaaaaact tgattgatga
    32761 agcacataaa agagggatac gtatcatgtt cgatgctgta ttcaatcata tgggtgtcca
    32821 ttcaccacag tggcaagacg ttctcaaaaa cggagaaaaa tcgatctata aagactggtt
    32881 ccacatccgt tttttcccag tagattctta tcagatgact gacttaccag aaactgctga
    32941 aaatatccca tatgatactt ttgcttttac tccattcatg ccgaaactaa atacagcaaa
    33001 tccagaagtg caaaaatatt tgctggatat cgcaacttat tggataaaag aattcgatat
    33061 tgatggatgg cgtcttgatg ttgctaatga agtcgatcat catttttgga aaaaattcag
    33121 agaagcagtt acagaaatca aaccagacat ctatatcctt ggagagattt ggcattcctc
    33181 tcaagcttgg ctgcaagggg atgaattcca tgcagtgatg aattatgcat tcacagattc
    33241 gattaaagat tattttgcaa aaaagaaaat cacagcttca caaatggtca gtggaatgaa
    33301 tcatcagcaa atgctttaca gagatcaggt gaacgaagga acattcaact tattagattc
    33361 tcatgatact gccaggatct tgaccctttg ccaaggtaac aaagaattga tgaagtctgt
    33421 gatggccttt atgtttcttc aaaaagggtc tccttgtatc tattacggga cagaaatagg
    33481 gatgactggt gaagatgacc cggattgccg caaatgtatg atatgggaga aggaggaaca
    33541 agatctagag ctattcggtt ttataaaaga acttgtttct ctaaggaaac agttgtctaa
    33601 gattatttct gaaggttcta ctcagtggct aatagtatat gatcgtgaag ataagctcta
    33661 tttcacacgg gaactagagg gacagatcat ctatgtttac tttaatcagt caaaagaacc
    33721 ttgggtagta gaacaggaaa atgaggtgat tcttagtcaa aattgtcagt tgttagaaga
    33781 cgggaaagca gagatacgac aatacggatt tttgatcatg tgttgaaaac tgttaccggt
    33841 aacaacaaga aagcgtttgc aaatgaagat ttgtgcccat tataataagg gtgtaacagc
    33901 acgttgaata cacaggagga aatgaagatg aaaaaaagaa gtgtgaaaca gttgggttta
    33961 gggttaatct ctttaggaat cttaggcgga ttagcggctt gtggcaatgg taactcttca
    34021 gcagaagggg aagccgatga aggaaaaacg ttaacagttt ccgttgattc tggatataaa
    34081 gattatataa acgaaataaa aaacactttc gaaaaagaaa acgatgtgaa aatcaagcta
    34141 gtagaaaagg acatgttcga tcagttggaa tcattagcgt tagatgggcc tgctggaaag
    34201 ggacctgacg ttatgatggc agcatatgac cggatcggtg cgttaggaca gcaaggacat
    34261 ctggcggaag taaaactggg aaatgaagca gcttacgatg aaacagacaa agcccaagtg
    34321 acttatgatg gaaaaatcta cggagaacct gcagtaatcg agacccttgt tttgtactat
    34381 aacaaagatt tagtcgatac agcaccatca acgtttaaag atttggagaa tctatccaaa
    34441 gacagtcgtt ttgcttttga gtcagaagca ggaaaaaata caggattttt agctaaatgg
    34501 actgactttt attattccta tggtttaatt gcaggttacg gtggctatgt atttggtgat
    34561 gatggcacaa atccttcaga tatcggtttg aataatgcag gtgctgtaga aggaatctct
    34621 tatgcaacag attggttcaa aaatgtttgg ccaaagggaa tgcaagacat aaaaagtgca
    34681 ggagacttcg ccagccagca attcatgtcc aataaaactg cagcaatcat tgacggtcca
    34741 tggcaagcgc aaacatacaa agaaaacaat atcaattatg gtgtagccaa aattcctact
    34801 ctaaataatg gacagcctta tcaaccgttt ggcggaggaa aaggatgggt agtcagcaat
    34861 tatgctaaaa acaaagacct ctctcaaaaa tggcttgatt atgtaacgaa tcaggaaaat
    34921 caagaaaaat tctttgaaat ggtaaatgaa atccctgcaa accaacaagc tagggaaaca
    34981 gcaaaggcta aaaacgatga attaacaaca gctgtgattg aacaatatga aacagctcaa
    35041 gcgatgccaa acatcccaga aatgggcgaa gtttggacag gtgcagaaaa cttgatgttc
    35101 gatgcagcat caggttcaaa aacaccaaaa gaatccgcag atgaagcagt aaaaacaatc
    35161 agtgaagcca tagaacaaaa atactgatta aaatgataac cgtccatttt tataaaaaat
    35221 ggaacaggtg cttcagataa aagtggcaag agcgagatgg aaaattatct tgctcttgtt
    35281 gccattatct taaaagcagt ttgcggttta gcaagtttag agggggcatt cagatgcagc
    35341 aagataaaac aagcaatatc aacgaaaaaa aaatcacgct ttgttcactt attccaggga
    35401 tggggcagtt tgtaaatggc caagctttta aaggtatcgt ttttttcgcc atattcgtcc
    35461 tattcattgg tcagatgctt ctgggcggat ttcatgcatt ggtaggattg gttactttgg
    35521 gaagtatacc aatggaagat cattcattat ttattttgat tgaaggcact ttgcaattca
    35581 tcattacaat cattttcttg attttttacg gtttgaatct tttagacgct tatcgagtag
    35641 cgaagatgcg tcaagagggc aaaaaaatca atcggacgat gaaggaagtc atacataata
    35701 taggtgatga aggttttcct tatctattga cacttcccgc ttatcttctc atgattttta
    35761 cgatcatttt cccagtccta gttacattgt tcactgcatt tactaattat gacttcaatc
    35821 atattccacc agccagttta attgattggg taggggctaa aaactttttt agtatcttct
    35881 ttttaagctc atatcgtaat actttttttg cagtcttttc gtggaccgtg atttggactt
    35941 tatgtgcaac aactttgcaa atcacccttg gtattctcac agcggttgtt gctcaccaga
    36001 aatttattaa attcaaacgt attttcggta tcattttctt attaccatgg gcggtcccag
    36061 cttttattac tatcatgagt ttttcgaata tattcaacga tagcgtaggt gccatcaata
    36121 ctcaagtgat tcctttcata aaccagcttc cttttgtaga tatcagtgca atctcttgga
    36181 aaacggaccc gaactggacg aaagtagcaa ttatcttagt gcagggctgg ttaggatttc
    36241 cctatatcta tgtgatggtt acaggaatct tacaatcgat ttcagaagac ttatatgaag
    36301 cagcaaaaat cgacggagca aatgcatggc agcgcttttc aaacatcacg cttcctgctg
    36361 tcttcctagt ggcagcgcca acatttatta cacagtatac ggggaatttc aataatttct
    36421 ccatgatcta tctgtttaac aatggtggtc ccggaagcgt aggcggagga gctggttcta
    36481 ctgatattct tatttcctgg atctataaac ttacgactgg aacttctccg cagtattcta
    36541 tggcttcagc aatcacgttg attatctccg tcatcgttat ctgtgtgtca ttgctggtat
    36601 ttaaaaagac aaatgcgttc aatatggggg attaacaatg aaaaaatttc attcgagtgc
    36661 tcgattccaa aaacgacttt ctcacttttt tacttacttt tttcttttaa tactgtcagt
    36721 cattatcatc tatccgcttt tgatcacagc aagtactgcc ttcaagtcag gaaatattgc
    36781 agcttttagt ttagatcttt caagtgactg gactttagga aactttactc ggctattcag
    36841 tgaaacactt tacgggactt ggtataaaaa tacattgatc atttctgtcc taacaatgat
    36901 cgtacaagtg actgtagtaa ctttggcggg ctatacttat agtcgctatc gttttatcgg
    36961 ccgcaaatca agtttgatgt tctttttagt gattcagatg gtaccgacta tggcagcatt
    37021 gactgccttt tatgtcatgg ctttcttatt agaagcgctc gataagtact ggttcttgac
    37081 aatgatctat ataggcggtg gaattccaat gaatacttgg ctgatgaaag gatactttga
    37141 cactgtacca atagatttag atgaatctgc taaacttgat ggggcagggc atttcaggat
    37201 ttttttccag attgtattac cgcttgtcaa accgatgctc gccgttcaag cattatgggc
    37261 ttttatggga ccttttgggg atttcatgtt agctaagttc ctgcttcgaa cacctgaaaa
    37321 tcagactgtt gctgtcggct tacaaacatt tatttctgat gtgacaaacc aaagagtctc
    37381 tctttttgct gctggggcaa ttttgattgc actaccgatt tgtctattat tcttcttttt
    37441 acaaaagaac tttgttaccg gcctgacatc tggcggaaca aaaggatagg agcagagtat
    37501 catgcaaaca tttccgttaa actatttttc cgcattacgt acgccaactc aagtgtttgc
    37561 gggacgcaaa ctattatcat ggcctaaatt tttcttgata tttgtatttt tagtttcctt
    37621 gatggtcatg cctgtgactc ttttttatgc caatcagatc caagcgattc cattagaaca
    37681 atttctatcc gttcattcgc tgatcgatga acaaggaacc caaaaatttt ctgaacttga
    37741 attatctgaa actgggttac aagcatcgca acaaacgata gctgtgaccc ctgaaatttt
    37801 ggtaggtgtg tctttatctg agaaacaaca atccgatcat ggaactttta ttgattttga
    37861 gaaggaacaa tgggtgatcc aacaaaagga taaatctggt atacgccgct atacgatgaa
    37921 ttatagccca tctttccaac cagattctgt acgtacgccc gaagatttcc aacgattttt
    37981 agaaagagaa ttttatgcca gtaatcgtcc aacaatcatt ttatcttata gtttaagtct
    38041 tggtcttgtc ctatttgtca tgacgagtct cattttattc ggggcttcct ttttcttgtg
    38101 gatgacaaga aaaagccaac tttcatccat tcatacattc aaagagagtg caaatttgat
    38161 gctgaatgtt atgggaatag gttccatggc agcagcagtt gtagggttta tccactttga
    38221 ctttatcttg atgctaagtg tccaaacaac gataactgtc ttgctgcttt tatgggtttt
    38281 tgtcaaaaca agattcaaag ataagcgtgt cgaatgacaa gtttaagcga tttatgcgac
    38341 aatgaatgtg aaaaaaatga aaaataaagt agtttttgaa aaatttctga aaaaattaaa
    38401 cttcttagtt gattcttttc ttttttagta ttaacgtaat agggtagttt ttttaaggag
    38461 gaaaatcatg ttagagaaaa ctttatacaa tcaattattt tcacgttctt tctcgctccc
    38521 tgtcgaagta aattattggg acggtacaac gaaacaatac ggagatacgg acactcctcc
    38581 ccaaatcaaa atcaatatcc atgaagaaat cccaatgaaa gagattacaa gtaacgcttc
    38641 tttggcacta ggagaagcct atatggatca tcgaatcgag atcgagggaa gtatccaagc
    38701 attgatcaac gatgcttatc agcaagcaaa cagcttttta cgaggaaaag attatctaaa
    38761 atggctgcca aagaaagaaa aacatacgaa acaaaaaaac aaagaagata tccatgcgca
    38821 ttatgactta ggtaacgact tttataaact ttggctagat ccaactttga cttattcttg
    38881 tgcttatttc aatacacctg aagatacgtt ggaacaagca caaatcaata aagtccatca
    38941 tatcttagac aaactcttta tcaaagaagg cgaaacgttg cttgatatcg gttgtggctg
    39001 gggaacattg atgttcactg ctaccaaaga gtataatgtc aaggcaactg ggatcacact
    39061 aagtgaagaa caatacgatt tgattaccaa aagaataaaa gaagaacatt tagaagataa
    39121 atgccgtgta ttattaatgg attaccgcga actaaaaggc gaaacgtttg atcatatcac
    39181 aagtgtaggt atgttcgaac atgtaggttc tgaaaatctt gaaggttatt tcaaagtggt
    39241 aaaagattta ttgaaaccaa aaggaacagc tttgatccat ggaatcagcc gacaacaagg
    39301 cggtgcgaca aatgcttgga tcaataaata tattttccct ggcggttatg tccctggtgt
    39361 tactgaatta gttgataata ttacaaaaaa cgatttgcaa ctgattgatt tggaaagctt
    39421 acgtcgtgac taccaattga cattagaaca ttggacaaag aattttcatc aagtccaaga
    39481 tcaagtcacg aaagaaatgg gtgattcctt ctatcgaatg tgggatctat atttacaagc
    39541 ttgtgcagct tcatttgaat caagtaatat cgatgtgatt caatatttgc ttgttcaacc
    39601 tggaaacaat gacatcccaa tgcatcgtgc ataattgagg caaaagtact gtttaaagac
    39661 tatttaaaaa gaagctaagt tttatgatgc tccagaagtg aacttttttg tctaacttct
    39721 aggattgtct ctaaagctta gtttcttttt ctttatattt tcataataaa agtttggttc
    39781 tttaattttt aaacatgaca gaaaattttt tcttcgttat acttgtaata gaatactatt
    39841 ttataacaaa ggggatcgaa tcaatgaaaa aaactgttat ttatactagt ttatttgcag
    39901 ctttgttttt agctgcttgt caatcaaata ccaatcaagg cacatctggg aatacgtctt
    39961 ccagtagcga acagcgctct tcacaggtat cggactcctc aacaaaagca agcacatctt
    40021 cgtctagcca gacaaaaagt tctagtgaag caagtactca gtcagatatc aaagtgtctg
    40081 cagctcgtgc gatcgaattg ttccaagata aatacccaga tactgcaatt actagtttgg
    40141 aattagatag tgattgggga tcttacttct acaagataga aggtgtcgat gatcaaaaag
    40201 aatacgaagc aagaattgat gctcaaaatg aaaaaatgga gacagagaat ccagaaactc
    40261 tagatcgaga tgaacaaaat ggtcaaaaga aaaaagaaga tggtctggat gttgataaat
    40321 tgatcacgat tgaggaagca gcaaaaatcg ccgtcgacaa agtaggaagc ggtacggcaa
    40381 cagattggga tttggataaa gatttaggta ctacttattg ggaagtcaaa gtaaaagacg
    40441 gcaatcaaag tacatcagtc aagatcaata gccaaacagg cgaagtactg tcaactgaac
    40501 aagatgatta agaatttctt cggaaaacaa gagttgattt ttcttttagt catgatacac
    40561 tagacaaaat aacttgtttg aaggagcgat ttacttgagt ttagaaacga cctttgccaa
    40621 tcatatcttt gccaatcctt tgatgaatgc atctggtgtc cactgcatga ctacccagga
    40681 attagatgaa ctggctcatt cagaagcagg agcatttatc actaagagct gtacgatcaa
    40741 tgaacgaaaa ggaaatcccg aaccacgcta ttttgatgtt cctttaggga gtatcaattc
    40801 tatgggactt ccaaacttag gtttttctta ttatctagag tatgctcttg cgtatgaaaa
    40861 agtgcaggaa aaccaaaatc aaccgttatt ttttccattg ccgggatgag tgtccaggaa
    40921 aacttggaaa tgcttgagaa aatagaaaaa agtgggttta atgggatcac tgaattaaat
    40981 ttatcttgtc ccaatgtgcc tggaaaacca caactagctt acgattttga ggccacttat
    41041 gaaacactga aagaagtatt cagcatcttt tctaagccgc taggaatcaa attgcctcct
    41101 tattttgatt ttgctcattt tgatcagatg gctgatatct tgaatcagtt tccattgacc
    41161 tatgtcaatg ctatcaacag tgtgggcaat ggtttgtata tcgatacaga acaagaagca
    41221 gtagtcatca aaccaaaaga agggttcggc ggcattggcg gagagtatat caagccgact
    41281 gctttggcga atgttcgcgc tttttataca cgtttgaaac cagaaatcca aatcattggt
    41341 acaggtggga ttcggacagg acaagatgca tttgaacatc tgctatgtgg cgcaagcatg
    41401 ttacagattg gtacagagct tcataaagaa gggccggaaa ttttttctag aatcataaaa
    41461 gaattaacgc agattatgtc agaaaaagga tatacgtcaa ttgacgaatt taaaggcaaa
    41521 ttacgcacca tttcatagca aagagacgaa ggtcatgatt gatcttcgtc tttttttata
    41581 aaaaacactc gtctgttcat tcctgtgcaa gcgtactcat tgtatgttag acgaacttgt
    41641 gggaaaataa cagaggcaaa aaggaggata atatgaatga tgcaacagaa ttagcaaaag
    41701 agcttaaaga aaaagaattt agttttcaag aactagttac ggatatacag aaaaaaataa
    41761 agaagcaaaa tcatgaattg aatgcgtttg tcgcgcttga accattcgag agtaattccc
    41821 acgagctatt gattccccag tcagaaaaag ggccattggc tggtatccca tttcctttaa
    41881 aaatgctcgg tcaagaaaaa aagggatggc tagctacttc aggatctcgt ttatttgaaa
    41941 cacaccgagc ttctcataca tctaattatg tgcggcaagc agaagcgata ggtctagttc
    42001 cttttggaca aaccaatgcg ccagagtttg gtttcaaaaa tattacagac ccagtcatct
    42061 atggcccagc aagaaaccct tggaaccttg aatgtacacc gggcggatca agtggaggag
    42121 ctgctgctgc agtttcatca ggaatcgttc ctttagctgg tgctagtgat ggcggtggtt
    42181 ctattagaat acccgcttcg ttttgcggat tgattgggct gaaaccttcg cgagggacga
    42241 tgccagttgg tccatatgct tggagaggat ggcaaggagc tgctattgat ttcggcttga
    42301 cagtttctat gagagacacg gaggcttttt tttatgggat gagaagtatc cattccggtg
    42361 cgccatatca agtatcgcca gttgagtggc aaacacatcc aagaaaaaaa cggttgaaga
    42421 tagctttttg tgttgattca ccgatccact cacagattag tgaagaggca gtacttgctg
    42481 taaaaaaagc tgtagatttc cttggaaaag aagggcatga tttgacagag attccttacc
    42541 cactagatgg tcgtaaactg atcacgtctt attatcagat gaatggcgca gaaacagcag
    42601 caatgatccg ctcgattgaa acaggcatcc agcgagctgt cagaaaagaa gaacttgaac
    42661 ccatttcttg gactttgttc caatatggtc agaagctctc tgccgctact tacatcgatt
    42721 ctctgcatgt atgggatgaa gcagcaattg tcatggaaaa cctacatcaa gaatacgatc
    42781 tattcctttc accaacgact gcatttaccg cccctaaaat cagcgaagat ttgcaaagtg
    42841 atgcgataag agcacagatg gaacacatca gtgattgttc tgaagtagaa ggtttagacg
    42901 ttgtttcttc catgtttgag gagagcttga agatcacacc ttatacacag ttggctaatc
    42961 tgactggaca accagcaatc agcttgccta ctcatttgac aaaagaaaac atgcctctag
    43021 gaatccaatt tatggctgcc agaggaagag aagatttgct atttcaaatc ggctatctat
    43081 ttgaagcaaa tcatcagttc catttaccaa atccatggaa atagcagaaa caaggagaag
    43141 aagaatgaag aaaaaaagat tgtttgctct aataactagt gcctttttta ttttaagcgc
    43201 ttgcggtaca gctgccgcta atcaggaaga taacagctgg agtaatgtag aaaaaaagaa
    43261 agaattagta gtagcgactt ctggcacact gtttcccgca tcttattata atgatcaaaa
    43321 tgaattagtt ggttatgatg tagatttggc aaaagaggtg gctaaacggt taaatgtcaa
    43381 aatctccttt aaagaataca acgtggatgg acaaatcact tctgtttcaa aaagagaatc
    43441 agattttgct gcgaacgatt ttggtatcac aaaagaaaga gaaaaaaaat tctccctttc
    43501 agagactttc aaatattcat ttgacagtat gatcgtacga aaaaaagatg attcaggaat
    43561 ccactcactt gaagatctta aagggaaaaa agcagctggc gaacccaata ctagctatat
    43621 gcgtttagcg gaaaaacacg gagctaaatt agtcacatat gacaatgcca cgaatgatca
    43681 gtatttaagc gatgtagcaa atggtcgaac agatgttatt ctaaatgatt attatctgca
    43741 gaaaatggcc gtatctgctt taccagatat ccctgtaaaa atactggaga acgtttattt
    43801 caatgaaaac gaaagtggtt ttttattgaa agaaggaaat gatgctctga aaaagaaaat
    43861 cgatggcgta ttaaaagaga tgaaagaaga tgggacgaca aagaaaatat ctgaaaaata
    43921 ttttcaaact gatgtttcag tcaaaccgaa agaaacgatg gctgagtcgg tgagtgagtg
    43981 atgtactttc ctctaattga tttttccctc atgtggactt cacttccttt cgtactgcaa
    44041 ggcttggtat acacattagg gattggcttc gtgtcgtttc ttttaggaaa tttggtaggg
    44101 ttgcttttga cagttttagg tcttttggat tggctgcctc tgaatgtatt tattcgtttt
    44161 tatttatcgt tctttagagg cattcccgca ctagtcctgc tgtttctgtt atatttcggg
    44221 ttaccttatc aattaagtgc cttaacggct tcagtcatct gctttacgat taccagcagt
    44281 gcatttattg gtgaaatcta tcgaggatca ctagcaggcg tttcttcagg tcagtgggac
    44341 gctggtttag cttctggttt ttctttcttt ggggtattga aatatatcgt tttgccgcaa
    44401 gcttttcgaa tctcagtacc ggcactcagt aacgtagcta tggatctagt gaaaggtact
    44461 tcgttagcag caacaatcac agtgccagaa atatttcaaa aagcaaagat cataggcggt
    44521 cggacattcg attatttttc tctctatatt ttagttgcac tgatttattg ggtcatttgt
    44581 atcgggatcg aaaaagtgca acagtattta gaaaaacgtt ctatccatca gtcaatctga
    44641 aaaatagaaa tggtgctagc gtggctggca ccatttctat tttttgtttc ttgtatattc
    44701 tgcctagtat tttaaaacca tttcatgtaa aatgtaaatc gaaaatatgt tcggaggtag
    44761 aaaacatgaa gaccccgcta accatcgaaa tagaatcctc gttataccaa tattgcatcg
    44821 agcaaggcgg cttggttgta gaagaagtca cgatgcctga tgaccaagga attgtagata
    44881 cgcttagctg cttgacaaaa tttgatggaa gccgagaatg gcgatgctat gagctgaaag
    44941 tgacaaaagc agattttcgc tctacagcca aactgtcatt tgttggacat tataattatt
    45001 ttgttttacc aagtaaacta tatgaagaag taaaaactga aatccctaca ggaataggtg
    45061 ttttagtgta tcgtccgtac acggttgaag aggagatgcc tgcctctggt acatttctga
    45121 ttgcgaaaaa agcagcaaag aaagagcttg ctgtaccgga agaagctttg acaaaccgct
    45181 tcatggcttc tttattcagg gaagtaagaa aagcaaagca aatggagcga ggcgtaaaat
    45241 attttccaaa agatcaattg tacaaagaat tgaaaagacg ttcagaaaat caagatccat
    45301 tttctaacga acgatattat gaacggtttt tagaggaaat agctagtcag gcaatcaatg
    45361 agttgcaaga agaagttatc gcgcttcagc atgattatga atatttgagg caacaacagc
    45421 agatccgtcg gttgcctaca gagccattgg agtgaaaaat atgtactatc cttatttaag
    45481 aggaaaacaa tttgacctat tagcattaaa agaagcactg tcgcgaggat tgctctccaa
    45541 taaaatccaa ccagtgatcg aaccagtacg tgattccgct acgcttaaaa atgtgatcga
    45601 attatttcaa aaaaagcacc atccaatcgc tgtgatccaa aatccccaag taggacaatt
    45661 caaattattc gatcagcatg tgcacagttg gacagtcaaa gaaaatagct ctgtcgtccc
    45721 tgcacagatc ttaacgccag aaaatctcag tgaagtactg gattcacctc cagcgtttct
    45781 tgttttcgat ggacagcact acccaaaaga tacagaggtg tggaaacagt tggcaggagt
    45841 tgattcgaaa tttttgatac cagatactag tcgctttcgc atctggctgc ccgaaaacaa
    45901 aattgtgatc cgtgactctt ttcaaacgag aaagcatgtt gaaagttatg cagataaaac
    45961 agatgacttt tttagtgatg actatctttt tttccacgca gacggatata ttggattttc
    46021 tgatttcacg atcgaaggta gccgttattt cgataaaggg ttccctagcc gagcgcttgc
    46081 tatccatcta acgtatattg atgcttacgg caatatacgc gtgaaacatt ttgtctctga
    46141 cagtaacgac tctgctaaag accaagcatt gaagtttctt gaagcaggag ataaaatgaa
    46201 aaaatggatc atgcgtcacc atcatcaact cttgattact tcaggaatga ttgaattatt
    46261 ggctctttac cagcaacaaa aattccctgg actgggagtg ttgaaaaagt ggtcacttat
    46321 gcatcatttg gaacttatta gtcacctgct agatcatcca aaagattggc ttaaatatta
    46381 ttcaaaagtt caggaactat atgaagtgat ccaatgatta gataatgtaa atgaaaaagg
    46441 aatagaaaag aggaaactgg atgtatattc ggcaaacaag gaaagaagaa gtagaagaag
    46501 tggtagaaat cattaatgcc gcagcggatt tcattgcttc gcaaggctct cctcaatggc
    46561 aaaacgggca gaaaccaaca aaagaaacga ttttgaacga tattgaaaga aaagaaagct
    46621 atgtattaat agtggaagat caaattgctg gaacagctgc attagtctca ggcgtggatc
    46681 ccgtttacac aaaaatagat ggtagttgga aagaatcaac tggtccttat ttatcgattc
    46741 atcgtgtcgc tttagcagaa agtactcgag gaaaaaaact agcaaaaccg ttcttagaac
    46801 atttgttgac gattgcagcc agcaaaaata tccaagatat ccgtatcgat acttatccag
    46861 ctaatgaacc gatggaaaag accatctatt ctgctggatt cacttatcaa gggatgattg
    46921 aatttccttt tgaacacggc gaaagaaaag catatcaaat aatcatcaat tgactataaa
    46981 atcatctgag caaagataaa gacattaaca ctactgaaaa aaacaatcat atgatagcca
    47041 agaggttgta acagaagtgg ccagcttcaa aaaacaagaa agaatttccg aaaatgcttc
    47101 tcaaattttt gtggaatttt agcgtatttt acgaaatagc tgctttctga aactcccttc
    47161 atcgagaggt cgtgacatag cttttgtcac gatctctcgg cttatcctac gagtattatt
    47221 cgatacattt atatcaataa tccttttttt attttatctg cagcttcttg gaacgctcca
    47281 tcgtttgaca cgactaaaag tgaggggata gctttcaaac gtttcaactg tgctaaatct
    47341 tctacataaa ccgccagtct ggctgaaatc tgttcagatg aatctccacg ttttttcagg
    47401 cgcgattgca atgtttcttt agagatcgta ataaagatag gacggactac cgtcccgaaa
    47461 tactcatata aatgccaaaa accatttgct gtcaaaacgg cgtaacaatt tcctactgtc
    47521 agtttctttt taatttctgc tttactggaa ccatatttat gttgagcata ttggtcccac
    47581 tctgcaaact catttccctt gatcatctga ttgaatgtat tgtcagaaac aaaataataa
    47641 tcctcttgat ctttttcccc aggtcttggt gatcgattcg tgtaagtaat gatcttttgt
    47701 tccggctgaa aaatagcttc tgcgagtgaa gtttttccag aaccagaagg accgataaat
    47761 acatagcaat aattcattgt catttctcct ttgatgattg aacaagtgaa aaagctttgg
    47821 aaaatatttc caaagctttt aaaagtaact ttgctttttt gtattttata ccagcaagcc
    47881 agtcacaata gcacttaaaa agctgactaa agtcgctgtt agcaaaattt tcaatccgtg
    47941 ttttgcgaca agatttcctt tttcttcatt taatcccttc atcgcaccag aaatgatccc
    48001 gatagaagag aagttggcaa atgaaacgag gaagacagat ataattgctg ttgtacgctc
    48061 agtaaaatgg aaattaccat ttgctaattc tgtcatagca acaaattcat ttgtaaccag
    48121 tttagtcgcc atgatactac cggcatccac tgcttctttc catgggattc cgctgatgaa
    48181 ggcaagaggg gcaaagatgt aacctaggat ctcttggaaa gtgatgccga atatcccgtg
    48241 gaagatagca ttgatcatgg caatcaaagc aacaaaaccg ataagcatag cagcaaccgt
    48301 gatcgccaca tggaaaccat caagaatgta ttctcccaac atttggaaaa atgtctgttc
    48361 tttgttttct tcaatgatca gctcatcttc tttttcttct aatacatagg gatttacaat
    48421 tgaagccaga atataaccgc caaataagtt caaaacaagg gcagtgatca catatttaga
    48481 atcgatcagt gccatataag atccgacgat cgacatagaa actgtagaca tagccgatac
    48541 actcatggtg aacaaacgtt tctcagatag gaagggtaat tcctttttta tggaaataaa
    48601 aacttccgat tgtcctaaaa tagcagaagc tactccatta taagattcca atttgcccat
    48661 cccgttgatt ttacttaatc ctagaccaac agctttcata aataatggaa gaatcttgat
    48721 atagcgtaga ataccgataa tagcagaaat aaatacaatt ggcatcaata cggaaagaaa
    48781 gaaaggtgca cttcctttat ttgctacacc ggcaaaaaca aagtcaacac cttgcccagc
    48841 aaaagcaaga agatgatcaa acatttttgc caatacagaa acaaccgctg taccaaaagt
    48901 tgtacgtaat aatacgaaac caagaacaag ctgtaaaacg aacatcacaa ttagtggttt
    48961 caatttgatt gcttttttgt tactgctgat caaaaaagca agccctaatg tgacaaataa
    49021 accaataata cctaataaat aactcaaata atcactccta ttccaaattc cgttttattt
    49081 tacctgtttt gcaaataaaa tactaatctt tagtgaaatt ttcattactt ttttagagtg
    49141 aaacgcattc attttccatt agaaaataaa gcgaacaaaa taaaaggttt aaaaagtgta
    49201 acgtcttagt aaagtctata aaaaaacgaa actatcgatt aagctaatag tttcgttttc
    49261 aacatttata agtaaacttt ttctattggt aatatagatt ttcggaaggg tagacaggtg
    49321 cgcaggtaat atcgattcct agttttttca atgtttgttc atcattttta ttgaccatca
    49381 cagtagagtg ggcttgtgct ccctcaagtt cagctagttt atcataagca acttgagcga
    49441 ttggattcgt tactgcactg attgataaag cgatcaagac ttcattgatg cttagtgcat
    49501 ccaaagagga atgaagtgtc tttgatttca atccttgtat tgtttcaaga actaatggtg
    49561 acaataaagg aatgtcatct gcgatatggg ctaaatgttt tactgcattt aagataactg
    49621 ccgctgacgc atccatcaat gaacttgtac gcccggtaat gatgacttca tctggtaatt
    49681 cgattgcaat cacagcagaa ggatcttttg taggactttg cgcttgaatc ttatctgcat
    49741 agtcatgggc agggactacc acgtttcggt cttcaggacg taaaccgact tcttccataa
    49801 tcagtttgat tcgattaact gcttcttcgt cgatcaatcc ttttttgaag tcgcattctg
    49861 tttggaaata acgacggatg atttcttgtt tagaggcttc ttggacaacg gtatcatcca
    49921 cgatcccaaa tcctacacga ttcacaccca tgtcagtagg agattgataa acagattctt
    49981 taccagtaat tttttcaata atacgtttga ttacaggaaa tgtctcaaca tcccgattat
    50041 agttcacagc tactttattg taggcatcaa agtggaagga atcgatcata ttgacatctt
    50101 ttagatcgac tgtggctgct tcataagcaa tgttcagcgg atgtttcaac ggaacattcc
    50161 atactgggaa agtttcgaac ttggagtaac cagctgcatg tcctttttgg ctttcatgat
    50221 acagttggtt caagcaagta gcgagctttc cacttcctgg gccaggagct gtcactacaa
    50281 cgattggttt agttgtttca atatactcat tttttccaaa accatcttct gagacgattt
    50341 tttctacgtt gactggatag tcttcgattt ctgagtgttt atagaccttg atgtttcgtc
    50401 tttctagttt attgataaag actttcgtgg caggctgtcc actatagcga gtgataacga
    50461 cactgttgat taataagcca taaccacgta attcatcgat taaccgcaag atatccatat
    50521 cataagtaat cccataatca ccacggatct tattacgttc aatatctcca gcatagacgc
    50581 aaatcagtat ttcagcttga tctttcaatt tttgcagcaa tttgattttc gcatcttctt
    50641 caaatcctgg aagtacacgt ttcgcatgct tgtcgtcaac taacttccca ccaaattcta
    50701 aatataattt gtcatagtgg ttcactcgtt ccaaaatata cgctgactgc tcttcaatat
    50761 atttttctga atcaaaacca atttttttca ctaggttccc tccttaagta ctaaagcatt
    50821 ttttcatttt tttgaggatt cgtcaactgg aagagcgaaa ttcctcaaaa aaacaaagaa
    50881 aatggtttaa accaacttgt ctagatagtt attcattggt atgatagttt ttgataagga
    50941 aggtgctaca tgaaaaaaag acagaaaaag aaaaacgcat ataaacacta tatccgttcg
    51001 atttttaccg gttatgaaag aatgcttgaa gatcccgaat tggaacaatt gacgtttact
    51061 tatctaaacg aagaaacgca gctaactcgt gatgagcatc agcgcattca tttcacaaca
    51121 agagatctgc ctagtaaata aaaaataaga taaaggtcat cggattcgat tctgtcctat
    51181 cagatggaaa gactagttga tcgaaaaaaa ggctgtacca aattttggtg cagcctgttt
    51241 tatggagcat tgcccgctct tttttataac aattttttac agaaaatggt actattgaag
    51301 tattaataag tgaaaaacag atgagtaaga ggaggcaagt agtatgaaag agccagatac
    51361 aaatgcaaat tatgagccag acgaactaga ggagacgaac gcggatcagg atacaggaca
    51421 agaatcgtct tctttttacg atatcaaaga aaaagcaagc atgaatcttt cccaattatt
    51481 agaagactta caggcttttg aaaaagctgt ccgcgaagaa gatatccctg agatctaccg
    51541 tttatacaat ggccgattga atgaagaatt aaaaagaagc tcaaatgaaa atcacgagat
    51601 cgatcaattg ctgatgcgta agatccatga tcgtttttta caggaatttc cttttatgga
    51661 acaagtagaa aacatctcgc caacgatgag ctattacaaa atcggcactt attaccatga
    51721 tcggcccacg gtcggtattg atgcaagtct gccagaaatt tttgttttgc ctaagatcga
    51781 tgaagagtgg gagaaatatt cccaaccgga gtcaacggac tatgacaaaa aaatcaatga
    51841 gctagacgca aaggtgatca ctgctcagac agaaattgaa cgtttagatg aacaaataaa
    51901 agaaatcaat cgacaaatga ctgatttgaa cgacaataaa ggattcttga atcgtaaaaa
    51961 aatcgaggaa gaaattcaag aattagagaa gaagaagcaa gtactatcta atgaaaaatt
    52021 aggctggctt ccttatattg agacgcctga aacaatccag cagcaaaaag aagcattgaa
    52081 gcaagaagca agagcagacc agcttcgtgc agccatcgta gaaaaagaac aaaggcaaat
    52141 cagacgctat ttcggtagca aagagggatt cggtcaagca atccatgaat tcttgatgaa
    52201 ttatcttggc aatgagaatc ctaataatca atctaatgaa ggaggttccg agtatgaatg
    52261 aacacgatga agcagaatgg acaaaaaatg aagaacaaac agaagatcat gaagaaacga
    52321 acacttcatt ggaagaacaa acaagtaatc ctctggatga cacagaagaa atccctatgc
    52381 tagaggaaac aaaaatacat gaaaaagaaa aagtaactcc gacgaatacg aatactgcag
    52441 aaaacaccca tgcttacgaa ataactgaaa atcccgggta tttagaagga aaagagcaag
    52501 atcatcaaga tatcgtcagt ttgattgaaa cagcggaagc agaattagcg gatttacgta
    52561 tgagaaaaga tttgatcgaa tcagattttc cacaattatt agaatcatat gatcgtttta
    52621 tattgaatga agaaccaatc tccacgatcg gaaagacaag cctgatcgaa tacttcacgt
    52681 atgaattact gaaaccgttg aatgatattg gtctggaacg gtcaaattca gcttatgaca
    52741 catggaaaac aagacatttt tcgatcaatt atacgttgaa tggacaaaac gaattagtct
    52801 tttcctttgt attaccgacc atcgatcaac gataccaagt ggaatcgatg agtctcctaa
    52861 acgtatcacc agagacaatg gaaatcaatg tccaagatga ccgggtgctt tctttgatcc
    52921 gacactggtc agtggatcga gtattctctg cagggcagat cacgatattc aatcacaaat
    52981 tgaatcaatt attagcccat gcaagaacac ttggttttac cgttaatcag acattactag
    53041 acaatacgaa gccacttcgt ttgaatcttc agagcgaatt tgaattgacg aatgaagtat
    53101 tggatgatat ttttatcgtg gcaatgaaaa atccatccta cgatatggaa aagatcaacg
    53161 aaactactta tcaagtacga ttagataaag gacagtcttt aacgataaca acaaacgaaa
    53221 aagatcaaac agtcttgtcg atctcatctg gagactaccc acgatctgtc attgatttct
    53281 ttatcaatta cgaattcttg gtcccattaa tggtgagaaa gtcctgattg gataagttgg
    53341 attaccagat gtcattcaga taattctgtt ccaaaggact tgcggcagtt atccagaata
    53401 attgtcacaa gtcttttctg tatgtactaa atggacgtga ataacttgct gatgaaggag
    53461 ggatttcatt aggaatgtcc acaaataaaa tagcacagct tagcttattg tctgctgctt
    53521 gtgtagcagg taggatcgct tttcaattta ttccgaattt ccagccaatg actgctattt
    53581 ttttatttat agtactttac ttaagcttaa aagatgcgtt aattgtcatg agtctttcta
    53641 ttgcgatcag cagtttttat tttggtgttg gaccatgggt catcggccaa tggatcagct
    53701 atactgttgt tctgagtttg ttttcaatcg tctgcttgag aaaaacagtg caaaggaatc
    53761 tatggttaaa gggagtctgt ttttttctgg cgggcatggt ttacggaata ggtatgaccg
    53821 tttttgatac gctgttatat cgtttgcctc aaccttggat ctattacctt caaggggtgt
    53881 cgtttgattt gatgcacagt ataggcaatg ttgtgttctt tcttgttttt ctgccagtcg
    53941 tcaaacgttt ttacaatcat tcaggaggaa aaaatgaaaa aaataattta tagtttgctt
    54001 gcaatgagtg tcagtatact cattttgaca agttgcagta caacctatac acaatcggct
    54061 tccaaccaaa aggaggaagt aaaaacatcg caaaaagcaa caatcacgtt acaagaaaat
    54121 ggtcaaaact tttcggaaaa agaagtggtc ttcaaaaaag gcgatgattt actgagtatt
    54181 ttgaaacgaa attttgaagt caaagaagat aacggcttca tcacttcgct tgaagggcac
    54241 tcacaggatg agaaaaatca actctattgg atgtttactg tggacgggaa aagtgctact
    54301 actggtgcca aagagatcaa attgaatgat ggacaatcgg tcattttcaa tttgtctaaa
    54361 ctataagttt cataaaaaac tgttaaaggg cgaatattgc cataattcag tgagttcagt
    54421 tgatgaaaga aggaaaataa catggaaaat tttaaaaaaa gcggaatgtt ttccgtaatt
    54481 gctgctctag gggctaatat tctagttgct atcagcaaat ttgtcggcta tgcaatcagt
    54541 ggcagtgccg ccatgctaaa cgaaagcatc cacagtatcg ttgattgcag caatcagatt
    54601 ttgctgttat tcggtgataa acaagccaat aaaggacaga gcgagttgca tcaatttggt
    54661 gaaggacgag caaaatactt tttcagtaca atcgtcgcaa tgatgctttt cttcggcggt
    54721 ggggcacttg gggtgatgga agcttttgaa aagttgacgc atccatccca tgaagtgggt
    54781 aatccgatca ttgttatagc aatactgtta tttggtttgg taatcgaagg aagttcgtta
    54841 cgcgtggcaa tgaaagaaat caaagaattg aatactgaaa aactttccac gatgcgcttt
    54901 ttgcgcgaaa gtcgacacag tgaaatactg attattttta cggaagactt gtgtgctgta
    54961 atcggtttgg tcttggcttt agcaggaaca atattgactt atgcaaccgg gattgctgca
    55021 tttgatgcga tcagcggatt gctgatcggt ttcttgctga tgggagccgc cattttccta
    55081 gcaaaagaat tttatagtct gatcatcggt gaaagcgtga cagcaagcga tttatcaaaa
    55141 atcaagttag cttttgaacg tcctgagatc agtcggctga tcgatataaa aacagttcat
    55201 ttaagtccaa cggagatttt agttgcagca aaagcagata tcgttggtaa caaagagaat
    55261 gaagcttact cggtcatcaa tgatattgaa aaaaatatgc gtcagtctct tcctgacaag
    55321 aagatgtata tatacattga aacagataaa tatgacccaa attattctcg taaataaaac
    55381 gtttattcat gaattgaagc aaaaatgaga aaaatataat cttgttttta aataaaacgg
    55441 ctacaattta gcgaatttat gttacaatga gtccgctgtt tatttgttgt aattaaagga
    55501 gatattttaa tgaacaaaaa gaaaagtgcg ccatggcttc aagctttgca tgcagtgatg
    55561 ccactttgta taagctatat accagtagga ttagcttgcg gagtattgtt gcaaaaagtt
    55621 ggatttgatc ctctcttatc aggactgtta tcgattctgg tcttttccgg tggcgcgcag
    55681 tttttagttg catctatgct tacgacgcaa gcatcatttg caacgacatt attgatggtt
    55741 ttctttttag aattacgcta tacattatta ggagcaagtc ttgccggttt tatgaaaaaa
    55801 gaaaagcgga cgtttttggc tgtcttttct caatcactga atgatgaaaa ctatgcggtg
    55861 aactacttaa agttttcaac tgacccttcc tggaataaaa gaaaggcttt atatgtcaat
    55921 tggttcgcaa tgactgcatg gaccggtagc aatatgatcg gtaatttttt cggctcggtg
    55981 attcgagtag atgctgacct tgtccatttt gctttgacgg ccatgttcat tttcatgttt
    56041 atcatgcaga tgaaaagcgc actactgatc tttacaggtt tattctcagg cgtattaggg
    56101 gtcgtattca tggtattatt ccaaaatact ttcggattga ttgcagcaac agtcattgct
    56161 tcatttgccg gatttatgct ggagaaggca ttcaaaaaag aaaaagctaa gaaactaaga
    56221 gaccgcggta aagatgtcaa tgagccgctc ttcaacttcc cggaacagga ggccaatcac
    56281 catgactaaa ctatatttgc tacttttagt tgcttgtctg ttcatcgtgg catatatccc
    56341 gcgcttgttc ccgatgcttt attttactca tcgaaaagtg ccatcctggt tcagtgactg
    56401 gatgaaatat gtaccggtgg cattatttgc ggcgttagct tttaaagatg ttttcattac
    56461 tcatgaacat ctggatattg cttggaatat caaaatagct gcaatgattc tagtagcagg
    56521 cgtggcttac aaaacacgtt cgatggcgtt gtcagttttg acaggacttg cgtctgtctt
    56581 tttgctgtct atgctttaaa ctgttttatt ttattaaaaa cagagattgc gacataagtt
    56641 gttcaaactg atctatccga actgcatttg caacagtcaa ttctggatgc aagtttattc
    56701 gtagggataa aaaagattag tgttggctta tgatgcaagc tcttttttat tttaggaatt
    56761 agagagggat ttgtccttct atgatttttt gctataatag ggaagatgtt tattttatga
    56821 aagaatagtt gagggaattt aaatgaataa aaaattgatg caaggaacat tttggctaac
    56881 ctttgctaat cttctatgta aagttttagg ggtagtctat ttgattccct ggctaagtat
    56941 gatggggaac aatcaagatg gtatgcttgc tacgacattg tataatgttg gctatcttcc
    57001 ttatggattg ttcctgatgc ttggtacagt cggatttcca aatgcgattg caaaaaaagt
    57061 agctgtagcc acaaaagaag gagataacgc tgcttgtcgg ctgattttta gaagtacgat
    57121 caatatcatg tttgtcatcg gtatcgcctc tgctgcactg atgtatttat ttgctccttt
    57181 actagccgga atcagtccga ttgctaacgt taataatggg atactagcta tcagaagttt
    57241 atgcccatct ttgattgcta tcccaattct tagtgcaatg agaggatatt tccaaggaaa
    57301 aaatgatctg cggccttatg gaacttcttt gattatcgaa caggctgtgc gagtgatcgt
    57361 tatcttggct ggtacttatt acttgcgcgt attgactgac ggaaccatat tagaagctgt
    57421 attgatcagt acagtcgctt ctttcttcgg tgggttagct gcgattatcc atatgtatat
    57481 cgtcggacgc agaaaagact tcttcgaact taaagatttt ttgatttcca gccgttattt
    57541 cgaaagagaa aaccgatctg cctctgtctc tatcattcgg gaaacactac cgtttatttt
    57601 tgtcggctca gtcattacta tcgttcaaat gatcgaccaa gtaacgatga aaccactgct
    57661 tcactttttc cgtccagaga tcgcagatca gcaactggaa ttcttattca gccgtgcttc
    57721 tgtcaatcca aataaattga cattgatcct gatctccatg gtaggaacag tagctataag
    57781 cagcttgcca atattaagca cgatgaagaa aaaagatcgg atacaaatcg aaaaaacagt
    57841 aggagatagt ttttcgattg cgttattgat tcttcttcct tcattgactg gaatgtcttt
    57901 attagctgga ccactataca cattgttttt tggctatgat cctgaaagtg tcggatattt
    57961 ccaaatggct ttgctagctt ctttgttttt ctctttattc acgatcctat ctacgatgct
    58021 tcaatctttg aatcaccatc gttttgcgat ccgattaact gtagaagcaa ttatcctgaa
    58081 agtcatcttc caagtaatcg gattaggatt agttggcgga tacgggatga gcttatcaaa
    58141 tggcttagca ttcggtattg tctttgttcg cggctatcac tttatgtgca aagaataccg
    58201 aatagcacct ttagcaaaga tcagcaattt tttcttaaaa actttccgct ccaccctgat
    58261 tatgcttgca gtatgttttg ccgttttctt tttgctgaat cagcgattgt caatggaatc
    58321 aaaaagctat gcaatgattt attgtgtggc tgtaggaagt attggcggct tagtattttt
    58381 attttctcaa ttcggaaaaa atgggtttcg aatgttgaaa aatgttaaac atcatagcag
    58441 aagcaaagaa taggttaact aatcgttttt tgctgtcact tgaaaaacgg caactcgtat
    58501 gattacgctt gtcgtttttc tattttccaa ttttagtttc atatctaatc ttacttatga
    58561 tatagttata aggtctggaa aaattctttg aaacgaggaa attaaacaca tgaaacttgc
    58621 agtagttaca gatagttcgg catatctgcc ggaacgtatc aagaaccatc ccgacttatt
    58681 cgttattcca atccctttga ttatggatgg gaaaatttat aacgaaggaa tcgatatcga
    58741 agcggatgaa tattatggac ttttaaaaaa cagtaaagat tttcctacta cttcacaacc
    58801 tgtcgtaggg gaagttttgg gtttatatga ggaattgaaa gagaaagggt atgacacgat
    58861 tttaagtatc catctttctt cagggatttc tggctttgtc aacacattat ttgcgatgaa
    58921 agatgacatc agcggagtaa cggtcattcc ttatgactct aagatcacta gtatgccgat
    58981 gggacacatg gtagaagctg ccttagactt aaatgatgaa ggtcagtccc ttgatgaaat
    59041 acttgcacat atcgatcgaa tccgagataa tacctatgct tatctgattg tagatgattt
    59101 gaacaattta gtacgaggag gacgtttgac aaatggtgca gcgctgattg gcagcttatt
    59161 aaaaatcaaa ccgatcctga cattttctga agggaaaatt gttttattcg aaaaaatccg
    59221 ttcaagtaaa aaagcatttg ctcgagctga agaaattatt ggtagaagaa ataacgaaat
    59281 acaaccgcca gtcaaacttt acgtgataca tgcaaataat ttagaagtag cgattgcgga
    59341 gaaagagaaa ttgcagaaaa aatatccaaa tgcagaaatc gaaattggtc atttcggacc
    59401 agtcattggt acacatttag gtgaaaaagc catcggcatt gccatttcag cgcaataatt
    59461 ccttttattc aaaaaacata ccaaaaat
//
LOCUS       DAPBCF010000012        58162 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.012, whole genome shotgun sequence.
ACCESSION   DAPBCF010000012 DAPBCF010000000
VERSION     DAPBCF010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 58162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58162
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.012"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..237)
                     /locus_tag="RD508_000923"
     rRNA            complement(<1..237)
                     /locus_tag="RD508_000923"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            978..1667
                     /locus_tag="RD508_000924"
     CDS             978..1667
                     /locus_tag="RD508_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7735537.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1654..2862
                     /locus_tag="RD508_000925"
     CDS             1654..2862
                     /locus_tag="RD508_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7735538.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            3156..4427
                     /gene="serS"
                     /locus_tag="RD508_000926"
     CDS             3156..4427
                     /gene="serS"
                     /locus_tag="RD508_000926"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDT7735539.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4976..6460)
                     /gene="guaB"
                     /locus_tag="RD508_000927"
     CDS             complement(4976..6460)
                     /gene="guaB"
                     /locus_tag="RD508_000927"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDT7735540.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6965..7660)
                     /locus_tag="RD508_000928"
     CDS             complement(6965..7660)
                     /locus_tag="RD508_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HDT7735541.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7750..8850)
                     /gene="ychF"
                     /locus_tag="RD508_000929"
     CDS             complement(7750..8850)
                     /gene="ychF"
                     /locus_tag="RD508_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDT7735542.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8859..9050)
                     /locus_tag="RD508_000930"
     CDS             complement(8859..9050)
                     /locus_tag="RD508_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HDT7735543.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(9071..9961)
                     /locus_tag="RD508_000931"
     CDS             complement(9071..9961)
                     /locus_tag="RD508_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDT7735544.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9948..10715)
                     /locus_tag="RD508_000932"
     CDS             complement(9948..10715)
                     /locus_tag="RD508_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDT7735545.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10727..11440)
                     /gene="rsmG"
                     /locus_tag="RD508_000933"
     CDS             complement(10727..11440)
                     /gene="rsmG"
                     /locus_tag="RD508_000933"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDT7735546.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11672..13573)
                     /gene="mnmG"
                     /locus_tag="RD508_000934"
     CDS             complement(11672..13573)
                     /gene="mnmG"
                     /locus_tag="RD508_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDT7735547.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13590..14987)
                     /gene="mnmE"
                     /locus_tag="RD508_000935"
     CDS             complement(13590..14987)
                     /gene="mnmE"
                     /locus_tag="RD508_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDT7735548.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            15286..15669
                     /locus_tag="RD508_000936"
     CDS             15286..15669
                     /locus_tag="RD508_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735549.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15837..16595)
                     /locus_tag="RD508_000937"
     CDS             complement(15837..16595)
                     /locus_tag="RD508_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HDT7735550.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16613..17431)
                     /locus_tag="RD508_000938"
     CDS             complement(16613..17431)
                     /locus_tag="RD508_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDT7735551.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17428..17784)
                     /gene="rnpA"
                     /locus_tag="RD508_000939"
     CDS             complement(17428..17784)
                     /gene="rnpA"
                     /locus_tag="RD508_000939"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDT7735552.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17902..18036)
                     /gene="rpmH"
                     /locus_tag="RD508_000940"
     CDS             complement(17902..18036)
                     /gene="rpmH"
                     /locus_tag="RD508_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDT7735553.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18559..19893
                     /gene="dnaA"
                     /locus_tag="RD508_000941"
     CDS             18559..19893
                     /gene="dnaA"
                     /locus_tag="RD508_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDT7735554.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            20091..21221
                     /gene="dnaN"
                     /locus_tag="RD508_000942"
     CDS             20091..21221
                     /gene="dnaN"
                     /locus_tag="RD508_000942"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDT7735555.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21450..21692
                     /gene="yaaA"
                     /locus_tag="RD508_000943"
     CDS             21450..21692
                     /gene="yaaA"
                     /locus_tag="RD508_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HDT7735556.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21679..22803
                     /gene="recF"
                     /locus_tag="RD508_000944"
     CDS             21679..22803
                     /gene="recF"
                     /locus_tag="RD508_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDT7735557.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22800..24746
                     /gene="gyrB"
                     /locus_tag="RD508_000945"
     CDS             22800..24746
                     /gene="gyrB"
                     /locus_tag="RD508_000945"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDT7735558.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24766..27237
                     /gene="gyrA"
                     /locus_tag="RD508_000946"
     CDS             24766..27237
                     /gene="gyrA"
                     /locus_tag="RD508_000946"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HDT7735559.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27473..27772
                     /locus_tag="RD508_000947"
     CDS             27473..27772
                     /locus_tag="RD508_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDT7735560.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27822..28334
                     /gene="ssb"
                     /locus_tag="RD508_000948"
     CDS             27822..28334
                     /gene="ssb"
                     /locus_tag="RD508_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDT7735561.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            28360..28596
                     /locus_tag="RD508_000949"
     CDS             28360..28596
                     /locus_tag="RD508_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDT7735562.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28739..30712
                     /locus_tag="RD508_000950"
     CDS             28739..30712
                     /locus_tag="RD508_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HDT7735563.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30718..31170
                     /gene="rplI"
                     /locus_tag="RD508_000951"
     CDS             30718..31170
                     /gene="rplI"
                     /locus_tag="RD508_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDT7735564.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31444..32811
                     /gene="dnaB"
                     /locus_tag="RD508_000952"
     CDS             31444..32811
                     /gene="dnaB"
                     /locus_tag="RD508_000952"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDT7735565.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33591..34883
                     /locus_tag="RD508_000953"
     CDS             33591..34883
                     /locus_tag="RD508_000953"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDT7735566.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35670..36533
                     /locus_tag="RD508_000954"
     CDS             35670..36533
                     /locus_tag="RD508_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7735567.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36662..38284)
                     /locus_tag="RD508_000955"
     CDS             complement(36662..38284)
                     /locus_tag="RD508_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7735568.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38533..39054
                     /locus_tag="RD508_000956"
     CDS             38533..39054
                     /locus_tag="RD508_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDT7735569.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(39240..40970)
                     /gene="spxB"
                     /locus_tag="RD508_000957"
     CDS             complement(39240..40970)
                     /gene="spxB"
                     /locus_tag="RD508_000957"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HDT7735570.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            41135..41953
                     /locus_tag="RD508_000958"
     CDS             41135..41953
                     /locus_tag="RD508_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HDT7735571.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(42056..42253)
                     /locus_tag="RD508_000959"
     CDS             complement(42056..42253)
                     /locus_tag="RD508_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735572.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            42422..43000
                     /locus_tag="RD508_000960"
     CDS             42422..43000
                     /locus_tag="RD508_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HDT7735573.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            43095..43232
                     /locus_tag="RD508_000961"
     CDS             43095..43232
                     /locus_tag="RD508_000961"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735574.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(44045..44548)
                     /locus_tag="RD508_000962"
     CDS             complement(44045..44548)
                     /locus_tag="RD508_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDT7735575.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44907..45932
                     /locus_tag="RD508_000963"
     CDS             44907..45932
                     /locus_tag="RD508_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7735576.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            46279..47157
                     /locus_tag="RD508_000964"
     CDS             46279..47157
                     /locus_tag="RD508_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HDT7735577.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47633..47749
                     /locus_tag="RD508_000965"
     CDS             47633..47749
                     /locus_tag="RD508_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HDT7735578.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48677..49015
                     /locus_tag="RD508_000966"
     CDS             48677..49015
                     /locus_tag="RD508_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735579.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            49109..49339
                     /locus_tag="RD508_000967"
     CDS             49109..49339
                     /locus_tag="RD508_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735580.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     regulatory      49813..49927
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            50063..51163
                     /gene="ribD"
                     /locus_tag="RD508_000968"
     CDS             50063..51163
                     /gene="ribD"
                     /locus_tag="RD508_000968"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HDT7735581.1"
                     /translation="MSDIEYMKIAIELAKKGAGYVNPNPMVGAVIVKNNRLIGQGYHE
                     VFGGLHAERNALKNCRESPVGATLYVTLEPCCHYGKTPPCTETIIKSGITRVVVGTLD
                     CNPIVSGKGVKQLEENNIQVDVGILEIECQQLIKVFRKYITKRIPYVFMKYAMTMDGK
                     IATYTNQSKWISGEKARKQVHQFRHKVTAIMVGVNTVIQDNPLLTCRLENGKNPIRIV
                     CDTDLRTPITSKIIQTANDIKTYIATSSIDESKIALYRKCGCEIIYTKKKGNHIDLMN
                     LMQCLGNMQIDSLLLEGGSALNWSALEQQIVDEVQTYIAPKIFGGSGKSPVSGQGVVF
                     PKDAIMLKPYAFSQVGNDYLIESEVIYPCLQE"
     gene            51148..51783
                     /gene="ribE"
                     /locus_tag="RD508_000969"
     CDS             51148..51783
                     /gene="ribE"
                     /locus_tag="RD508_000969"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HDT7735582.1"
                     /translation="MFTGIIEEIGKVERIQKDTYNCKLSIKSSKILEDIHLGDSIAVN
                     GICLTVTCFTRQSFIVDVMNETWNRTALNLLKHGSLVNLERAMHMNGRLGGHIVTGHI
                     DGTGRISSVRRDKNAVWYQINTQREILNLIVEKGSVTIDGISLTVAKVSKADFSVSVI
                     PHTLEQTILKNKQVGDMVNLENDILGKYVKKLIGNSNETELSKELLCRYGF"
     gene            51803..53008
                     /locus_tag="RD508_000970"
     CDS             51803..53008
                     /locus_tag="RD508_000970"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HDT7735583.1"
                     /translation="MKYKKIKEALQALQEGKLVLVMDDKERENEGDLICSAQFATTEN
                     VNFMATYAKGLICMPMSESLANRLMLSPMVENNTDNHETAFTVSIDYKDTTTGISAEE
                     RGLTARMCVVEDINPFDFRRPGHMFPLIAKNGGVLERNGHTEATIDLLRLAGLKECGL
                     CCEIMNENGKMMRTSDLIQFSQIHHIPTLTIKELQEYRKVYDMLVECVSVVEMPTKYG
                     DFKAHCYINKLNGEHHVALVMGELNSGNDVLCRVHSECLTGDVFGSLRCDCGQQLDRA
                     MKMIAENGSGVLLYMRQEGRGIGLVNKLKAYHLQDKGMDTLDANLALGFQGDLREYYI
                     GAQILRDLGIKSLHLLTNNPDKVYQLEDYGMQISSRVPIEIKANPYDSFYLKTKKDRM
                     GHILNMEEK"
     gene            53009..53476
                     /locus_tag="RD508_000971"
     CDS             53009..53476
                     /locus_tag="RD508_000971"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HDT7735584.1"
                     /translation="MNTFEGNLVAENIKIGIVVARFNEFITSKLLAGALDNLKRENVD
                     EKDIEVAWVPGAFEIPMIASKMVKSKKYDAIICLGAVIRGSTSHYDYVCSEVSKGIAQ
                     ISLNTETPVMFGVLTTDTIEQAIERAGSKAGNKGSECAQGAIEMVNLIRALEV"
     gene            54095..55309
                     /locus_tag="RD508_000972"
     CDS             54095..55309
                     /locus_tag="RD508_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDT7735585.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRIAVACGISREYYNRIEKGKQP
                     LNNELKEIIEKQIERFNPREPLFLLIDYFRVRFPTTDALKIIRDVLQLKADYMLYEDF
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGRGCRQMESYLLAQERSWYDFMLGCMT
                     AGGKLKRLDLAINDKAGILDIPKLIEKYKAGECISYFRKQKDYGGTEKNGYDTPQNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEVEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWKMNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDKENHTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTVVPQENDGIF"
     gene            56028..56238
                     /locus_tag="RD508_000973"
                     /pseudo
     CDS             56028..56238
                     /locus_tag="RD508_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
     gene            56350..57963
                     /locus_tag="RD508_000974"
     CDS             56350..57963
                     /locus_tag="RD508_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7735586.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFERPSFQRMIEDIEVGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAYYGA
                     YAPLGYKKHPDIKGKLLVDEETKWIVEKIFSLAYQGYGSAKITKILREEKVPTSSWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAQIKGILKSEVYIGNSVHNRQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIEKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     ATNKANKTPYSYYACSFYGQFGKGYCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LHKIQKVGNAERIREKKKKASALKKAENRQNEIDCLFAKMYEDRACEKITERNFIMLS
                     GKYQKEQIELEQQITDLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEENERIQEIEIYYRFIGKVD"
     gene            58061..>58162
                     /locus_tag="RD508_000975"
     CDS             58061..>58162
                     /locus_tag="RD508_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HDT7735587.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAII"
BASE COUNT        18359 a        10517 c        11569 g        17717 t
ORIGIN      
        1 gacacccgaa agcgcctttc aaatcaaaac catgcggttt cgattgttat acggtattag
       61 cacctgtttc caagtgttat ccccttctga tgggcaggtt acccacgtgt tactcacccg
      121 ttcgccactc ctctttttcc ggtggagcaa gctccggtgg aaaaagaagc gttcgacttg
      181 catgtattag gcacgccgcc agcgttcgtc ctgagccagg atcaaactct cataaaaagt
      241 tcgaacaatc ttgcgattgt taagctcaat ttgtttgcta gcatattgct tgcttgttaa
      301 aaatgtttgt tgtcttgaat tgaatcaaga cgccctacac atttggtttg tcttactttg
      361 ttcagttttc aaaggtctac ttcatcagga gtgtttcccg attcgttttt ggctgccgta
      421 gcaactttta tatcatatca gagagacaag taattgtcaa ctctttttta aaagtttttt
      481 cgatttcgtt tttcgaaatc ttccagcaac tcatttatca taacttatcg tttgttattt
      541 gtcaagaact tttttgaagt ttttttcgat agaatcaagc ttcgcaagtg gttctttttt
      601 aacgactcag ttatcttatc atgtcatttc caacatgtca acaacttatt ttttattatt
      661 taataagtta ttggtgttct tttgaacaaa taataatata tcaacatcac atgtgaaagt
      721 caataagaaa atgcttattt atcaacattt ctagcttaca tgatcattgg ttagttctgg
      781 tcctttttcg ttcgtcttta taactccgag agacgtaaaa tccttttgtt ttcagtttaa
      841 tgttcatgtt cttgtcttat tcacaccaac tagatgtctc accttctaaa attttcctta
      901 acaaagtgct gcttttatct atttctgctt ttttttgcta gaataatagt aacaatatga
      961 ctctggagga tttatttatg aaaattttga ttgctgacga tgataaagaa atcgttgaat
     1021 tattaagtat ctatgttcac aatgaggggt atgaagcagt aaaggcttat gatgggaaag
     1081 aagcattatc taaaatcaga acaatccctg atattgaatt acttatttta gatatcatga
     1141 tgcctgagat ggatgggatg caagtagtga aagagctacg aaaagaatcc caaataccaa
     1201 tcattatgct gacagcaaaa actactgata tggataagat caaaggactg gtcgctggtg
     1261 cagatgatta tgtgaccaag ccatttaatc cgttagaagt aatggctaga gtaaagtctt
     1321 tattacggcg tacaaaaatg cagattgccc cagatcagcc tgatgtatta gaagtaaatg
     1381 cattaatcat caataaagac tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt
     1441 taacagcttt ggaattcggt atcctctact tgcttgctag tcatcctaat cgagtattta
     1501 gcgcggatga aatttttgag cgtgtttgga aacaagaaag tattgtctct gctaaaactg
     1561 tcatggttca cgttagtcat ttaagagata agattgaaga agcaactggt ggtgaaaaag
     1621 tcattcaaac cgtttgggga gtgggctata aaattgacgc aagatagtaa acgagcaact
     1681 gaaaaacgcc gtcggatcaa tttgacttca aaagaaatca gcgaattgtt agcggaagga
     1741 atcatcacga ttatcctttt gcttctatta aatgtttcta ttctggttgt tatcagttcg
     1801 gtgatcaaca gttcaccttc tttgacgaat gcgatttggg attcaaagaa tatttttgca
     1861 gaacgattga acactgattt gttctggaac ggccggaatt ttattattcc ctttttcttt
     1921 ctattagata ttggtgtttt gtattggcgc ttgattcgaa gatatcgcca aatgcaattg
     1981 cggcatatca tcagcgaact tcactacatc gcaaacggaa attatgatca tcgtatccct
     2041 tttgaactga gtggtgactt aagccgagtg gtaacaagta tcaatggatt ggtggatagt
     2101 accgtagcag cgattgaaga cgaacgtaaa atcgaaaaat caaaagatga attgatcacg
     2161 aatgtcagtc atgatatccg taccccactc acgtccatca ttggatacct aggactgata
     2221 gaagatggcc agtatcactc agaagaagat cttttaaagt atacgcatac tgcttatatc
     2281 aaagcaaagc agatgaaatc tttagtggac gacttatttg aatacactaa ggtacgccag
     2341 cctgctgtcc cggtgaattt ttctgccttt gacatgatcc agttgatcga acagttagca
     2401 gctgattttg agttggaagc ttctaaaaaa aatatccaaa tacttgttca atcaaaagta
     2461 gactccctta tcatggatgg cgataccgaa aaacttgtac gtgtcttcaa taatcttttg
     2521 acgaatgcgt tgaaatacgg aaaaggagca acgaagatcg taatcgaagt agaacgtatc
     2581 ggttcagaag ttgttgcaac agtcaaaaat aacggagcaa tgatcccaca acaggcaatc
     2641 gataatctat tcgaccgttt ttatcgtgta gaagaatctc gttcacaagc aactggagga
     2701 actggacttg gtttagcaat cgctcaaagc attgtggctt tgcacggcgg atacatttat
     2761 gcaaaatcag ataagcaatg gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa
     2821 aaattaccta ttgatacaca ggaagttatt gacgaaagct gaaatattcg ctattcttat
     2881 tacaattatt agaataaatg aaaaacacag aacccagtac actttattct ttttcagaga
     2941 gctgatggca ggtgtaaatc agcaaaggat aatttggaag ttccagttcg tttacgtgcc
     3001 ctttcgaaat aagaaaggtc ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg
     3061 ctgaacttgg gtggtaccgc gaatttcaga ctgattcgtc ccaagaataa tgggatggat
     3121 cagtcttttt ttattttcaa aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac
     3181 aaaatattga agaagtacaa gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag
     3241 ctgaattcat ggaactagat gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa
     3301 aaaaatatcg aaatgatgtt tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg
     3361 cttctgctaa aatcgctgaa atgaaagaag tcggtggcaa catcaaagca ttggatactg
     3421 aaattgctga agtggatgaa aaattgaaac aaattgcaac tactttgcca aaccttcccc
     3481 atgattctgt gccagttgga acagatgaag aggacaatgt agaaatccgt cgttggagcg
     3541 aaccacgtac atttgctttt gaaccaaaac cacactggga aattgcagaa aatcttgata
     3601 ttttagattt tgaacgtggc gcaaaagtag ccggtagccg ttttgtctat tacaaaggat
     3661 taggtgctcg attagaacgt gctgtctaca acttcatgct tgatcagcat atttacgaac
     3721 acggctatac tgaaatgatc actccttata tcgtcaacag taaagcgatg tttggtacgg
     3781 gacaatttcc aaaattcaaa gaagatgttt tccaattgga gaatactgat ctaacattaa
     3841 tcccaacagc tgaagtacca ttaactaact attataatga tgaaatttta gatggtgcag
     3901 atttacctat ttatttcact gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg
     3961 gtcgggatac acgaggactg attcgtcttc accaattcaa taaagtagaa atggtcaaat
     4021 tttcggatgt agagcattct tacgaagaat tggaaaaaat gacagctgat gcagaagata
     4081 tcttgaaaaa attgcatttg ccttatcgtg tgatggcctt atcaactgga gacatgggct
     4141 tttctgcagc taaaacttat gacttagaag tatggatacc tgcacaagat acttatcgtg
     4201 aaatcagttc ttgttctaac tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc
     4261 gcgataatga tggaaaaatc cactatactc atactctgaa tggttcagga cttgcagttg
     4321 gccgtacagt agctgccatt ttggaaaact accaaaatga agatggttct gtcacagttc
     4381 cagaagcgct cgttccttat atggggaatc tgaaagttat taaataaaga ggctgtgaaa
     4441 aagccgctta gtttcgagta ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc
     4501 ataaattgga cttaataccg agaaactggc ttttgaacac catttatcga gaggttgtga
     4561 aatcagcgaa ttaacctgag tattagagaa aaaaatggaa aaatagtccc tcatatttta
     4621 ccgtttgttg aactaatacc gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt
     4681 aagcctaccc cccagctcct agttacaagg acaaattcaa aaaacagctc ttcatatttt
     4741 atgaatgttg tacttgtgat tcggaggtgg caagggaaca ctgtttattc aaaaagaggc
     4801 tgggacagaa gcgtttaact ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa
     4861 tttttgtgaa tttcttctta tttccgaagg agttgcttct acttccgccg tttatacgtg
     4921 tttagagcgt gagacaaaag tgttctttac ttttgtccca cgctctttaa tgtttttaag
     4981 attcaactga atagtttggt gcttcttttg tgatttgtac atcatgaggg tgtgattctt
     5041 ttaatccact gccgctcatt tggataaatt gcgcttcatc acgtaattgc tgtagattgg
     5101 ctgccccaac ataacccatt cctgaacgca aaccgccgat catttggaaa ataatatctg
     5161 caacacttcc tttataagca acccgacctt cgattccttc tggtactaat ttatttgctt
     5221 cattgacact accttggaag taacggtctt ttgaaccttt ttccatcgcg cctaatgagc
     5281 ccatacctcg gtatgttttg aatcgacgtc cttggaagat ttcgaattca cctggtgatt
     5341 catctgtccc tgccaacata cttcctagca tcactgcatg tccgccggca gctaatgctt
     5401 tgacgatgtc accagaatat ttgatccctc cgtctgcaat aatcgctttg ccatattgac
     5461 gagcaactga tgctgcatca taaatagctg tgagctgagg tacacctaca ccggctacca
     5521 cacgtgtcgt acaaatcgat cctggtccga taccaacttt tacgacatct acacctgcat
     5581 catataaagc ttttgtcgct tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg
     5641 caaaagttga acggatttct tgaatttttc ggatcacacc tgcactatgt ccatgagctg
     5701 tatcgatgat gattgcatct gcccctgctt ctaataaagc attcgcacgc tcaaatgtat
     5761 cgcttgttac accaacggct gctgctacaa gcaatcgacc atgttcatct tttgctgcat
     5821 ttggaaattc gatcactttc tcgatgtctt tgatcgtgat caatccgctt aaacgacctt
     5881 cgttatctac gattggtaat ttttcgattt tatgtttttg caaaatcttt tctgcatctt
     5941 ttagagaggt acctactggg gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg
     6001 gcatgtgata atctgttaca aaacgcatgt cgcggtttgt aattatccct accaattttc
     6061 tgttttcaag tgtttcaacg attggcacac cactgatacg atatttgctc atcaattctt
     6121 ctgcgtctgc tacaagatgc tgtggcgtta agaagaacgg atcaatgatt acgccacttt
     6181 cagaacgttt gacttttctt acttcatccg cttgctggct gatcgtcatg tttttatgga
     6241 tcacacctag tccgccttgt cttgccatag caatggccat cttgctgtcg gtaacagtat
     6301 ccatacttgc actgatgatt ggaatattca acttaatatt tttagctaat tgtacgctca
     6361 tatccacttc gtttggtaac acgtgacttt ctgctggtat caataagaca tcatcaaaag
     6421 taaatccttt tttcgtgaac tttgtttccc agttggacat ttttagtacc actcctctaa
     6481 tttagtttat ctattaaaat aattgatttt ttcatttaag tcaatgatct acttggaatc
     6541 aagttagctt tctcatagaa taccaatata aagcgtttac atctgtgtgt attaaaagag
     6601 attgtaaaaa agctgtcctg catcaagtaa taagaacagc caatcaaaaa cagcttctca
     6661 tgtttttgaa ttggttgggt ttattaccgc agatgcaaac ttttgaacac cgtttagtgg
     6721 agaggctgtg aaaaagctgc ttagtttcga gtagtaagaa aaattttgtg aaaatggctt
     6781 tccacatttt tgcataaatt ggacttaata ccgagaaact ggcttttgaa caccgtttat
     6841 cgtaaaaagg gactgtgaca agacttttgt cacagtccct tactattatt taactatgga
     6901 taaacaaaat gaggttcttt actaccccta gatatctagc aaaatagctg atctttttgc
     6961 tagtttatct tcttgggacg gataaacttc caataatccc gtattttttc ttcaagtagt
     7021 aacggattgc taaagcagtt gccccgataa tgataactac tactggatct aatactggat
     7081 tgataactgg tggcaatagt gttgtcgcag aaaacagtac gacccaaaga agtgtcgttc
     7141 cacctaggat aagcaatgtc ttacccattc ctggtttctt gcttcgatct gctccgggat
     7201 attcatattg atagatgtat ttgtacatca tataaaagac ccagccaccg attgcagaac
     7261 ctagaacgag tgtagaaaag ccataagctg gcgttgttcc acgtgaaaac aatccggtaa
     7321 tcgcaatcat gatacttaat agaccaagca acagcaacgt attatctaac cacatcaata
     7381 aaggggtgga tgaatttttt acttctgctg gcttattgat gattgcttcc gttctttcag
     7441 agactgtccc aaacaattga cgggctgttc ttccgccttt ttgttctgca actaaagtag
     7501 gcagaatgtc atgaagggct tttacttttt cttcttcaga caaattcgct gcttctaaag
     7561 attttttcaa atcaaaaatg tactgttgat ttcttttggt taattttgtt tctaaactat
     7621 tgttttcttt tacgattgct cgtaattgtt ctggttccat tatctaatag tcctccttag
     7681 ccgttccttt tctcaacggt cgtcacaaaa gacattctac catattctac agctagtttg
     7741 atagcccttt tacacattaa agcggaataa cattacgtcg ccgtcttgta cgacataatc
     7801 ttttccttct aatcgaacac gtccagcttc ttttgctgca tgcatgtttc cgtaatgatc
     7861 caagtcttca aaagagacag tttctgcacg gataaatccg cgttcgaaat ctgaatggat
     7921 gattcctgct gcttgtggtg ctttgattcc ttttttgaat gtccaagcac gtacttcttg
     7981 ttccccagca gtaaagtaag tagctaagcc taacaaatca taagcagcac ggatcaactg
     8041 atccaaacct gattcttcga ttcctaaagc ttctaaaaat tccgctttgt cttcttcatc
     8101 taattctgcg atttcttctt ctgcacgagc actgaccacg atcacttctg cattttcttc
     8161 tgcagcaaag ttgcgcactt cttgtacata atgattcgcg tctgcatctg ctacgtcatc
     8221 ttctgagaca ttggctacat aaagaattgg ttttgtcgtc aataaaaata gtgatttaac
     8281 gattttttgt tcttcttcag taaattcgat cgttcgggca gattttcctt cttccagtac
     8341 aggtttgatt ttatccagta cagctagttc tgccactgca tctttatctt tggttttagc
     8401 aacttttgct acacgagtat agcgtttgtt gatagattct aagtctgcta acactagttc
     8461 caagttgatc gtatcaatat cttctagtgg atcaacacgt ccttctacgt gagtaatatt
     8521 atcatcatca aaacagcgaa caacgtgaca aatagcgtct acttggcgga tatggcttaa
     8581 gaattgattt cccaaacctt ctcctttact tgcgcctttt acgattccag caatatctgt
     8641 aaattcaaaa gtcgtcggaa cagttttttt cggatgtaca agttctgtta agcgttgcaa
     8701 acgccagtca ggtacttcta ccatccctac gttggggtcg atcgtcgcaa agggatagtt
     8761 tgctgcttct gctcctgctt ttgtgatcgc attaaacaaa gttgattttc ctacgttggg
     8821 caacccaaca attccagcag tcaatgccat aaatttattc actctttctc tgcatttttt
     8881 tcaattactt tttttaattt cttttcaaaa tctcgacggg tcatcatgac gatatgtccg
     8941 caattcatac atctgatttt gatatctgcg cccattcgaa tgacttccca gcgattcgtc
     9001 tggcaagcgt gaggtttttt catttcaacg atatcgtgca agtcgtacat aaaaatagcc
     9061 tcctttttgt ttattcttca tcaaattgaa tattcaagat atcaagaatt cgagtcaaat
     9121 ctttttgaga aagatattca atctcgatct tacctttccc atttttttct tggatagcta
     9181 cacttgtacc aaatttatcc atcaaacgat cttcgctttc tcggatataa tatggttttt
     9241 cctttgctag ccttgggatt tttttctttt cttttccatc attttgattt aactcagaaa
     9301 caagctgttc cagttggcgg acagttaaat tttcagttac tgcacgattg gctaatttca
     9361 agatcaatgt tttatttttt aaacctaaca gcgtacgggc ttgtcccata gataaacgct
     9421 gatcttgtac catttccttg acaagatccg gtaaagaaag caagcgcaaa taattggcga
     9481 tataaggtct gctctttcct aaacgactag ctacttctgc ttgtgttagt ttcaggtttt
     9541 tcatcagcat ctcatatgct tctgcttctt ctaacggatt cagatcttct cgctgcaagt
     9601 tttccagcac tgctacttgc atcatcgctt cttcgtcaaa gtctctaacg atagcaggga
     9661 tcgtttcttt ttcagctagt ttggacgctc gaaaacgtcg ctcccctgca ataatctcat
     9721 atccttttac tgcggaacgg cgtacgatga tgggttgaaa gacacctgat tgttcaatag
     9781 aattagctag ttcctgcaaa gatacttctt caaatgtttt acggggctga tacggatttg
     9841 gtcgcagctc attcaatggt agctggacaa cggtatcatc ttttacatcc accgtctcta
     9901 agttttctaa atcttgaaac agtgcatcga ttcctcggcc taatccttta cttttcttca
     9961 cgacttacca cttcctttgc caatgcttgg tagacttcag ctcctcgaga acgtggatcg
    10021 tagtcgatga tcggttttcc atgactaggt gcttctgata aacgaatatt tcttggaatg
    10081 atcgtttcgt aaactttttc gcggaagtat ttacgtactt cttctacgac ttcatttccc
    10141 agatttgttc gtgcatcata cattgtcagt aagactccct cgatctctaa ttctggatta
    10201 aagtgttttt ggactaaacg aaccgtattc agtaattggc ttaatccttc caatgcgtaa
    10261 tactcacact gaacaggtat caaaatcgaa tcacttgctg taaatgaatt gattgtcaga
    10321 tggccaagag aaggcgggca atcgatcaaa atataatcat actgactgct tacttctgct
    10381 aaagatcctt ttaatcttga ttctcttgcc atcattgacg tcaattcgat ctctgctcct
    10441 gctaattgga gagtcgcagg cacaatactc aaattttcgt gttcagtgat caaagttgcc
    10501 tcatcaattg gcaattcatt gactagaaca tcatagatgt ctcttgtcac atcaggtttt
    10561 ctgatcccga caccactggt agcatttcct tgtgcatcca tatccactag caatactttt
    10621 ttgccaaggc tagcaagaca agcacctaga ttcaccgtcg tcgttgtttt gccgacgcca
    10681 cctttttggt tcgcaacaga tattatttgt gccatctctt ctcctcctat ttgattggct
    10741 gcttattagg cagtccgggc tttcttgggt atttctttgg ggttggtttc tttttttgaa
    10801 taacgatgat atgccgttga tcagagacat tcggcaaggt aaccgcctct tctttgagga
    10861 atttaccacc taataaagca atcgcttgtt ttgcttctgt caattcctct tcactttttg
    10921 ctgctttcaa tgcataaaaa tagccttctt gtttagccaa gggcaaacac aattccgcta
    10981 acacattcaa acgagcaacc gcacgagcag tgacaaggtc aaatgatgca cgaaagtgag
    11041 gattttgccc aaatgtttct gcccggtcat gatataagga agcatcgatt cctaataatc
    11101 gggttaactc agataagaag gttattcgtt tattcagaga atcaacgatc gttatctgca
    11161 gttctggaaa ggcaattttt aaaggtatgc taggaaaccc tgcccccgaa ccaacatcgc
    11221 ataaagataa aggttgcgta aagtctactt caaatgctaa tgtaagtgaa tcgtaaaaat
    11281 gcttcagata tacgtctttt tcatccgtaa tagctgtaag gttcatcttt tcgttccatt
    11341 cgactaatgt ccgataataa atagcgaatt gattcatttg atgatcggta agctctatcc
    11401 ctttttctgc caaggattgg cgaaattctt ctggtatcat aaatattcct ttcattgtga
    11461 aacagcaatt gtttcacaga ttctctccct actttaacgc aaaatctcta gacatgcaat
    11521 ccttccatat ggattcttaa aaatttgaaa agtaagaaaa gccgatagac tttttctttc
    11581 tagtatgact cataaaatat acacagaaga gagaactagc tttgagcaat ttctgcaaaa
    11641 actagttctc tcttctattt attattacgt attacgctgg ttcactgact ttcgcaatct
    11701 tcccttgttc gatatagacc attaggatac ttaggtctgc agggtttacg ccactgattc
    11761 ggctagcttg ggcaattgtt tctggttgga ttttctgcaa tttttgtttt gcttctgttg
    11821 ctaatccgtt gattgctgcg tagtcgatgt tttctggaat ctttttcgct tccatgcgtt
    11881 ttaatttttc tactttttcc atggcttttt tgatgtagcc ttcatatttg atttggattt
    11941 ctacttgttc gatttctttt cgtgtcaatt cttcattttc tggaataaac cgtagaagtt
    12001 ctgcataagt aatctcagga cgtcttaaaa agtcgcttgc tagtacacca tcttttaatg
    12061 gtgccgcatt aatcgttgct aaaaagtctt ggacttcttc tgttggtttg attcgtacat
    12121 tcatcaaacg tttgatttct tgttcaactg cttctttttt cttcaaataa ttcttgtatt
    12181 gatcttcttt tactaagcct acacggtgac ccatttctgt taatcgcaaa tctgcattat
    12241 catgacgtaa aagcagacgg tattcagcac gtgaagtcag caaacgataa ggttcgttcg
    12301 ttccttttgt taccaaatca tcgatcatga caccgatgta accgtcactt cgtttgatca
    12361 ctaaaggttc ttttccctga actttcaaag ctgcattgat accggcaatc agcccttgtc
    12421 cagccgcttc ttcataaccg cttgtaccat ttgtttgtcc agctgtataa agattttcaa
    12481 cgactttagt ttctaatgtc ggacggagct ggtgtggctc tactacgtca tattcgatag
    12541 catatcctgt acgcatcatt tctacttttt ctaatccagc aatagaatga agcatgttga
    12601 cttgaacatc ctctggtaaa gaagtagata aaccttgaac atagacttct tccgtattta
    12661 agccttctgg ttccaaaaat aattgatgac gtggtttgtc tgcaaaacgc acgatcttat
    12721 cttcgatgga tggacaatag cgagcgccta ccccttcaac gatccctgta aacattgggg
    12781 cacgatgtaa gttgtctcga ataatttggt gagtcgtctc acctgtatag gtcagccagc
    12841 aagattcctg atctagttta taggcactat ctggtgtgct gaagctaaaa tgattcggct
    12901 ctttgtcacc aggctgctct tctgtaacag aatagtcgat cgtacttgat tttactcgag
    12961 gcggtgttcc tgttttgaac cgttcgatag caaagccaag ttcttttaga tgattcgcta
    13021 gtccaataga aggttgagag ttattcggac ctgatgaata tttcaattca ccgataatga
    13081 tttctccgcg aagtgctgtt ccggctgtaa taacaactgc tttggcccgg tagctcgctc
    13141 ctgtggacgt cactactcca tgacaaacac catcttcgac gatcagttct tcgacgattc
    13201 cttgtcttag cgtcaaattt ggttcttttt cgatcgtatg tttcatttct gttgaataag
    13261 catgtttgtc tgcttgtgct cgcaatgctc ggacagctgg gccttttcct gtgttcaaca
    13321 tacgcatttg gatataggtt ttatcgatat tcttacccat ttctccgcct aacgcatcga
    13381 tttctcgaac gacaacgcct ttagctggtc cgcctacaga aggattacat ggcatgaatg
    13441 ctaccatgtc caaatttatt gtcagtaata atgtttttga tcccatacgt gcagcagcaa
    13501 gtgcagcttc tgaaccggcg tgtcctgcgc caacaacgat cacgtcatac gcatctgctt
    13561 cataatgttc caatcgtttg ttcctccttt tattttccta aacaaaattg actgaataat
    13621 tgagtgatta gctcatcttg tacactgtcg ccgacaactt ctcctagata gtcccagcaa
    13681 cgcgtcatat ctatttgaac gagatccaca ggcattcctg aatcaatacc tgcaatgact
    13741 tcttcaagtg agagggaagc tttttctaac aacgcgatat ggcgggtatt agaaacataa
    13801 gtagcgtctc tttctcctgt ttctccgctg aagaataaat cagaaatagc tgattccaaa
    13861 cgatctagtc cgtcgttttt agctacggaa attgaaaaaa ctggttcatt ttcgatcaat
    13921 ttcttcaatt tttcttgttc cagctgtgct ggcaaatctg ttttatttag aagaatgatc
    13981 cgtttcaatc cacttgtcgc ttccaataat tgttcatctt ctgctgtcag tggttcgctt
    14041 tggtttagaa caagtaagat caagtctgct tctgctaatg cttttcggct tctttcgacc
    14101 ccgatccgtt ccaccacatc ttctgtttcc cgaattccag ctgtatcgat tagcttgagc
    14161 ggtacccccc gaacattgac atactcttcg attacatctc gagtcgttcc tgcaatatcc
    14221 gtaacgattg ctttttcttc tcttaacaaa tggtttaaca aacttgattt gccgacattt
    14281 ggccggccga tgattgccgt acttaaccct tcccgcagaa ccttcccttg cttggatgta
    14341 gcaagtagcg cttggattct ttgttggatc atctgcgctt tttcaagcaa taacttcgta
    14401 gtcaattctt cgacatcatc atattctgga taatcaatat ttacttctac ttgtgctaat
    14461 gtctctaaaa tctcttgtct caatgagcgg atcaaagcag acagattgcc gtctaactga
    14521 ttaagagcta gtcccattgc tttgtctgtt tttgcccgaa tcaaatccat cacagcttct
    14581 gcctgtgaaa ggtcaacacg accattcaag aatgctcgtt ttgtgaattc gcctggctca
    14641 gctaatcttg caccttctct taacaatagc tgcaaaattt gattgactac aacgatccca
    14701 ccgtgacaat tgatttctac tacatcttcc cgcgtaaatg tctttggtgc tctcatcacg
    14761 gagaccatga cttcatcgac aagctgattg ctcttgggat caacgatatg tccataatgg
    14821 atcgtatgac ttggtacttc tgataatcgt ttgtttccag attgataaac tttatctgct
    14881 agttgcacag cttgatcgcc acttaaacga acgatactga ttgcaccttc tccaggtggg
    14941 gtagaaattg ccgcaatcgt atcaaattct aaagtaattt cagccatttt ttcacttcct
    15001 ttttcatttt gcgcacaaaa aaagtgccca ctccaccctt tatgcacaat aaacggtgaa
    15061 cttcgcactt tgactgcttg ttcttgatta aattctggtc atagattatc acacttgcta
    15121 taaggaatca agtgtttaaa acaattagat gaagttgagc ctgttctgct tccattacct
    15181 tatatttaat tgtccttgga tgtctctttg cgttctttgg tttattcgaa gagaagatac
    15241 tgtataaaca aggctttatc tttcttaaaa aaaacggtac actaaatggt agcgctatct
    15301 aaactataca cttttgaaag gagaaaatat gtgagcccgt tcagatctgc tgcattggaa
    15361 gaagaaagtg accctcggat caacgatgtc gttttatcta cagggaatat caaccagaaa
    15421 tatatcgtcc gcgatatcgt ttttgttgtg gaatgcttag aagctgattt gtttgaccca
    15481 tcttttccca aagatgacct tttcttaaca acgaagagga aattaaagac gaaggtactt
    15541 gaatatggtg cgaatgcagt aatcaactgt cattttgagt atcagcaaaa aaaacgcgac
    15601 ggaaagtatt ttctggaact ttttgcttat ggaacagtga tccaatttat ccaaacaacg
    15661 attggttaaa tgaaacagac aaaaaaagcg gatcaaaact gaagacagtt tcgatccgct
    15721 tttttctatc aaagttagtg actacttcat cgtatactct gataagaatg atttctagta
    15781 aaatatactt ggtttgaaaa actttgtcaa cgtgatttat tcaaaaagta atggaatcaa
    15841 taatattttt tagcaggttc tactactaaa taacgataag gttcctcacc ttccgaatgt
    15901 gtttttacat gttcatcttt gcttaatgca gcatggattt gtttacgttc aaatgcaggc
    15961 attggttcta agaaaacagg ctgccctgtc cgttttactt tttcagccgt gcgatcagct
    16021 aaacgctgaa tgatctcttg gcgcttttca cggtaattgc ctacattgac tactacagac
    16081 agcttatttc ttgctaaacg atggatgaag acttgtgcca gatattgcaa tgcattcagt
    16141 gtttttccat gtttcccaat cagtatgcct tgcttttgtg tttctaaatg gaaaacaacc
    16201 atattatttg attctctttc cattttgaca agagctggag catcaagctg ttttgaaatt
    16261 tcagtaagat aaactgccaa ttccgttaaa gctgcttcat cacctagctc acttacttct
    16321 tctgtttttt cttcaagaat cgtttcgttg actacctcga tctcagctgt tggttcttct
    16381 tccaaaattt cttctacagt ctgttctact gtttcagaaa ctttttcgct gatacttggc
    16441 tggatcgaaa gccgtgcatt ctttcgaccc attcctagga aacctttttt tccttcttcc
    16501 agtatttcga tttcgacttg gtctttggcc aaacccaaat cagccagacc tagttggaca
    16561 gcttcgtcta ttgttgcagc ttcataaatc ggcattagca ttacctcccc tattatttcc
    16621 gttttttctt aggattcatt gctttcttaa gagcacgttc tctttcgcgg attctccgtg
    16681 cttcttcttc acgctctttt cgaattttga aagggttgtt gatcagcagc gtttgtacaa
    16741 cttggaaggc attggaaact acccagtata atgaaagacc gctggctaaa ttgacaccca
    16801 tcactaaaat cattacaggc atcacgaaat tcatgatctt cattgatgca ttcgattcaa
    16861 tttgactcat gctagataaa tacgtacttg caaaagtaaa gattgctgct aaaatcggca
    16921 aaataaatgt tggatccgcg ttccctaagt tcaaccataa gaaatgccct tgtttcaact
    16981 ctggtacacg tgaaatagat tgccataacg ccatcaagat tggcatttgt actaataaag
    17041 gaagacaacc agcatatgga ttgacgccat tttctgcata taaacgctgc tgctcttctc
    17101 ttaacttact ttgtgtttcc ggatctcttg aactatattg ttgctgcagt gcttttaatt
    17161 tcggttgtaa ttcttgcgtt ttacgcatgc tctttgtttg gaaatgcatc aacggcaata
    17221 ggatcacgcg gatgatcagt gtaaataaaa tgatccctat ccctgcatta ccaaatgaca
    17281 acgccttgat cgcctcagca aagtaataaa caatataacg atcccaaatt cctgtactct
    17341 gtgcgctgac ttccccagtt ccgcaaccgg ataagacgat gaccaaacta acgataccgg
    17401 ccatcaaaag taaacgtttg tatttcttca cttactcttt tcctctctgt cgattatttt
    17461 tgcaagtttt aagacgtgga ctaaattgga gcgaacctca tcataagtca accccttcac
    17521 acttggtcta gcaatcacaa taaaatccaa ctccggatca atttcttctt ttatagaata
    17581 aactgctgct cggatttttc gtttgacttc attgcggttt accgcgttgc cgaccttttt
    17641 tcctacagat aaaccaactc gaaaatgagg ctgtcccggt ttttccaaac ggtaaacgac
    17701 gaatttgcgg ttagcaaaag aatctcccgt atggaacacg gcttgaaact ctcgttcttt
    17761 ttttactcga tacgcttttc tcattagttt tctttccttt tctatctctc acttacgctc
    17821 ataatcatac cataattacg attgtccttt catcatttcc ctaaaaaaga gtataaaaaa
    17881 aaccactgaa accccagtgg cctaagctga aagaactttt cttcctttgc gacgacggct
    17941 agctaacaca cgacgtccat ttttagtact catacgttta cggaatccgt gaactttttg
    18001 acgtttacgt ttatttggtt ggtatgttct tttcatatat tccacctcca aaatgttctt
    18061 atctatttta taaacacaga catactttga tagtataacg acaaagtagt gattttgtca
    18121 atataaaata gaagatcgat tgttaaaact tatccacaag attatttttt tctatgggaa
    18181 tcctatgtgg aaaaagttat gcacagggat tatccacaga taataaaagg ctggttttac
    18241 acagaaaaca cacgtgtaaa aaaagtaatc cacaatcagg cgatttcctg tgtattccgt
    18301 ctcctaacta ttggtatatc tgtatttttt atccacagac gcaagaggaa atctattggt
    18361 ttttacgagt tttccacctg tgcattagtg gtgtggaaaa ctttttttga caactgtgtt
    18421 tttctctttt ttctttttgt cgattgtgtg gataattgta attaaaaaat ttttttcttc
    18481 ggtttctgtg gaaaactatt gaaaaaaatg ctaaattagt actagttatt cactttttaa
    18541 tgaaggagga ggccttatat ggtatccctc gatgctttat ggaatgaatt aaaagcaaca
    18601 taccaaaagg atttatcgcc tgctagctat aatacatgga tcgaaacagc gaaccctcga
    18661 acccttgatc aaaaccagct cgttgttgag gttcctagca agattcataa agaatattgg
    18721 gaaaaaaacc tggcgacaaa aatcgttgaa gtcggttata tgttatcagg aaatgagatt
    18781 atccctcgct ttattactgg cgaagaagca gagcaagaag aagttataga agaaaaaaat
    18841 ccaaaagttg tggcacctag tccgctaaaa aaagccatgc tgaaccctaa atataccttt
    18901 gatacgtttg tcattggtaa aggaaaccag atggctcatg cagcagcgct cgttgtagca
    18961 gaagatccag gttctattta taacccgctc ttcttttatg gaggcgtggg acttggtaag
    19021 actcacttga tgcatgcaat tggtcatcaa atgctgcaaa gtcagcctaa tgccaaagta
    19081 aaatatgtaa gcagtgaaac ttttgctaat gatttcatca attcgatcca aaacaaaaca
    19141 gcagaagagt tccgtcaaga atatcgaaat gttgatttac tgctagtgga tgacattcaa
    19201 ttttttgcag aaaaagaagc tacgcaagaa gagtttttcc atactttcaa tgccttgtac
    19261 aatgaaggga aacaaatcgt actaaccagt gatcggttgc caaacgagat tccgaaactg
    19321 caagaacgcc ttgtttctcg ctttgcatgg gggctgtctg ttgatattac accgccggat
    19381 cttgaaacaa gaacagcgat tttacgtaaa aaagcggcgg ctgaacgtct agagatccca
    19441 gatgacacac taagctacat cgcaggacaa attgattcta acattcgtga attagaaggt
    19501 gcgcttgttc gagtgcaagc ttttgctgcg atgaatagtg aagatatttc gactagtcta
    19561 gctgcagacg cactgaaaac gttaaaatca ggaaaaggac atcctcaatt gtcaatcctg
    19621 cagatccaag aagaagtggc aaagtattat cacatccaat tgaaagatct caaaggaaag
    19681 aaacgcgtca aatctattgt tgttcctaga caaatcgcta tgtatttggc acgtgagctc
    19741 acagataatt ctttaccgaa aatcggagct gaattcggtg gcaaggatca tacaacggtt
    19801 atccatgctc atgaaaaaat ccagcagctg atggattcta gtgtcagtat gcaaaatgaa
    19861 gtatcagaaa tcaaaaactt tttactaaat taatttgtcg attctatcaa ctgaaaatag
    19921 catgtggata aaagaaaaaa acgttcaaaa gttatacaca ctttttccac agctgttttt
    19981 tcgtttctct cttacgtttt ttgagttttc cacagaatca acatgcccta ttacttttat
    20041 tattcttttt aactaataat aaataaacaa acattcaaag gagatacatc atgaaagtta
    20101 ctttaaaccg agctagcttt atgcaggaat tgcaaactgt tcaacgagct atttcaagca
    20161 aaaccacgat ccctattttg acaggtgtaa aaatcacact gacacaagaa ggtttgactt
    20221 tgacggggag caacgctgat atatcaattg aaactttttt gtctgttgaa aacgaaaaag
    20281 caaatatgca aatcgaatct actggttcca ttgttttaca agcacgtttc tttagcgaaa
    20341 tcattcggag acttcctgaa gaaacattta ctttagaagt tttagaaaat aaacaagtag
    20401 cgatcacttc tggaaaagcg aattttatcg taaatggatt agatgcagat aactatcctc
    20461 atcttcctgt tgtcgaaagc cataaccaga tgaaattacc tgtacacgta ttgactaaac
    20521 taatcaacga aacagttttt gctgtctcac aacatgagag tcgtccaatc ttgacaggtg
    20581 tgcatttcat tttatctgat aattctttat tagctgtagc tactgattct caccgtctaa
    20641 gtcaacgcgt gattccagta gaacaagcgg ctgatcattt tgatattgtt attcctggaa
    20701 aaagtttgat cgaattatct cgctcattaa caaatgaaga agaaatcgtc gaaatcagca
    20761 ttatggaaaa ccaagtgttg ttcaaaacag aaacgatgta tttctattcc cgtttgctag
    20821 aaggaaacta tccagatacc aatcgtttga ttccttcaag ttttaataca gaggttgaat
    20881 tttctgttcc tagcttttta gcggcgatcg aacgggcttc tttactttct catgaaggcc
    20941 gtaacaacat cgttcgttta tctattcgtc cagatgcggt tgttttatac ggaaattcgc
    21001 cagaaatcgg gaaagtagaa gaaagcttga gttatacagc aagcagtggc gatccattag
    21061 atatttcttt caatccggat tatatgaaag cagcgttgcg tgcatttgga gatatgagca
    21121 tcaaagtgaa atttatctct gctattcgtc catttacatt ggaaccaacg gaagatggcg
    21181 ttcaatttat tcagctgatt actcctgtac gtacaaatta acaatgattt tcaatgttct
    21241 tgaaaattta attgaaaaga aatagaaaaa ataaaatttt aaacagaagg ccctaaaatc
    21301 tcttttaagg ctttctgttt atttttgttt aaatcacctt ttttagatta aatcgtctta
    21361 tatggaaaaa tatatggata aatttgtttt attgcgaaaa aaaaggtata atagagtata
    21421 cttttaataa tgaaaatgag ggatgggcat tgaaacaaca agtcattcta aatacggaat
    21481 tcatgacgtt gggccaaatg ttgaaagaag tcacagttat cggtagtggc ggacaagcaa
    21541 aatggtattt ggcagaaaac actgtgttag tcgatggcga accagaaaat cgtcgtggac
    21601 gcaaacttta tcccggcatg atggttgaag ttccagaagt aggaactttt tttatggtaa
    21661 aaaaaggaaa cgacgataat gaggctgaat aagctgtatt taaaaaatta tcgaaattac
    21721 gaagagctga acatcgaatt ttccaagaac ctcgtcatct ttttaggaga aaatgcgcaa
    21781 ggaaaaacga atcttttgga aagtatctac gtattagcta tgacgcgaag tcatcggaca
    21841 agtagtgagc aggaattgat tggctggact gacgatcagg cgatgattca aggagagatc
    21901 acaaaaggtt catccactct tccattagaa atcttattat ctaaaaaagg ccgaaaaacc
    21961 aagatcaacc atatcgaaca gaaaaagtta agtacttacg tgggacaaat gaatgtcatt
    22021 ttatttgcac cagaagatct ttctttagta aaaggcagcc cgcagatcag gcggaagttt
    22081 ttagatatgg aattaggcca gatcaatcca atctatcttt atgatcttgt ccaataccaa
    22141 gcaattttga aacaaagaaa ccagtacttg aagcaattga atgaaaaaaa acaaactgat
    22201 ttgctttatt tggatatttt gtccgaacaa ctagcagcgt ttggcagcaa agtattgaaa
    22261 gcaagagcac agttcgtcaa gcgattggag ttttgggcta attctttgca tcagcaaatc
    22321 acccatcaaa aagagcagct ggaaatcgag tatctcaccg cagtcgattc tttagaaaca
    22381 catacgcaag agcaaatcca agaacaattt ctcgcacttt tgaaccaaaa taaaaagaaa
    22441 gacctttttc ggggaacaac gacagttggt cctcatcgtg acgatctttc cttttttatt
    22501 aatcagaaaa atgtgcagac ttatggatcg caaggacagc aaagaacaac tgcactaagt
    22561 gtcaaattag cagaaatcga tttgattaaa gaagagacag gggaatatcc aatccttttg
    22621 ttagatgatg tgatgagcga gctggatgat aatcgtcaac tccatctgct agaaacaatc
    22681 gaaggaaaag ttcaaacgtt cttaacaaca acgacacttg accatgtaaa aaataaaatg
    22741 actgttgaac ctgagatttt ttatgttcaa caagggaaac taaaaggaga agaaactgaa
    22801 tgacagaaga aagaagttta gtagaacgcg ctaaagagta tgatgccagt cagattcaag
    22861 tacttgaagg acttgaagcc gttcgtaaac gacctggcat gtatatcggt tcgactagtt
    22921 ctgagggtct gcatcacctt gtttgggaaa ttgtcgataa ttcgatcgat gaagtattag
    22981 caggttttgc aacgaaaatc catgtgatta ttgaaaaaga caacagtatc accgttattg
    23041 acgacggtcg ggggatacct gtagatatcc aggcaaaaac tggacgtcct gcagttgaaa
    23101 cggtctttac tgttttacat gctggaggaa aattcggcgg tggtgggtac aaagtttctg
    23161 gtggacttca cggagtagga tcttctgttg taaacgcgct ttctacacag cttgatgtca
    23221 aagtatacaa agaaggaaat gtgtactatc aagaatatcg tcgtggagct gtagtggacg
    23281 acttaaagat tatcgaacaa acggatcgcc atggaacaac ggttcacttt acgccagacc
    23341 ctgaaatttt tacagagaca actgagtttg atttttcaaa attggctacc cggatccgtg
    23401 aacttgcttt cttgaaccgc gggatgcgta tatcgattga agacaaacga gaagaagaac
    23461 cagtcatcaa tgaataccat tatgacggcg ggatcaaaag ttatgtcgaa tacttgaatg
    23521 caaacaaaac cgtgattttt ccagaacctg tatatttgga aggtgaacag caagatatcg
    23581 cagttgaagt ctctatgcaa tatacagacg gctaccattc caatatcatg agttttgcca
    23641 acaatatcca tacgtatgaa ggtggaacac atgaatcagg attcaagact gctttaactc
    23701 gtgtgataaa tgattatgcc cgaaaacaaa agctgatgaa agaaaatgac gacaacttga
    23761 ccggtgaaga cgtgcgagaa ggattgacag ctgttatttc tatcaagcat cctgaccctc
    23821 aattcgaagg acaaacaaaa acaaaattgg gcaattccga agtacggaca gtcactgatc
    23881 ggttatttag cgaacatttc atgaaattct tgctggaaaa cccaagtgtg ggccggcaaa
    23941 ttgttgaaaa aggattacta gcttccagag ctcgtctagc agcgaaacgt gcgcgtgaag
    24001 taacgagacg taaaggtgct ttagagatta gtaatctgcc aggaaaatta gcggactgct
    24061 ctagcaacga tcctgaaaaa tgcgaattgt tcatcgtcga aggagattcg gccggcggat
    24121 cagctaagca aggtcgtaat cgagagtttc aagccatctt gcctattcgt gggaaaatct
    24181 tgaatgttga aaaagcaagc atggacaaga tcttggcaaa tgaagagatc cggtctttat
    24241 ttactgctat gggtacaggg tttggagaag attttgatgt atcgaaagct cgctaccaca
    24301 aattagttat catgactgat gccgatgtcg acggcgcgca tatccgtaca ttgctgctga
    24361 ctctttttta tcgttacatg cgtcctattg ttgaagctgg atacgtctat attgctcagc
    24421 cacctttata cggggtaaaa caagggaaga atattacgta tgtacaacca ggaaaaaatg
    24481 cagaagaaga gttgaaacaa gtcgttgctt cacttcctgc ctcaccaaaa ccaagcgttc
    24541 agcgttataa aggacttgga gaaatggatg atcatcaact atgggaaaca actatggacc
    24601 caagcaatcg gatgatggcc cgcgtcagtg tggacgatgc tattgcagca gatcagatat
    24661 ttgaaatgtt gatgggggat cgagtagaac cccgtcgtgc attcatcgag gaaaatgcac
    24721 actatgtgaa gaacttagat atttaatcat gaaggaggaa aaagaatgag tgaagaaatc
    24781 agagaaaaca tccatgatgt caatctaacc agcgaaatga aagactcctt catcgattat
    24841 gcgatgagtg ttattgtcgc acgtgcactt cctgatgtca gagatggtct gaaacccgtt
    24901 catcgccgta ttttatacgg catgaacgaa ttaggtgtaa caccggataa agcccataaa
    24961 aaatctgcca gaatcgtcgg agatgtcatg ggtaaatacc atcctcatgg agacattgcg
    25021 atctatgagt caatggtacg gatggcacag ccattcagct accgttatat gctagtggat
    25081 ggtcatggaa actttggttc tgttgacggt gacggtgccg ccgctatgcg ttataccgaa
    25141 gcacggatga gcaaaatcgc tacagaaatg ctgcgtgata tcaataagaa cactgttgat
    25201 ttccaaagca actatgatga tacagaaaaa gaaccagttg tactacctgc tcgcttcccg
    25261 aatcttttag tgaacggaac aacggggatc gccgtaggta tggccacgaa tatcccacct
    25321 cataacttgt ctgaggtagt agcggctatc gatttgctga tggataatcc tgatgtgacg
    25381 accaatgaat tgatggaagt attacctgga ccagattttc caacaggtgg tttggttatg
    25441 gggaaatcag gaatccgaag agcgtatgaa acaggtaagg gttctattac cgtacgtgca
    25501 aaagttgaga ttactgagat gccaaatggt aaagaacgga tcatcgtgac agaattgcct
    25561 tatatggtca ataaagcaaa attgatcgaa cggatttctg aactgcacag agacaagcgt
    25621 atcgaaggga tcacagattt gcgggacgaa tcttcccgtg aaggtatgcg gatcgtcatt
    25681 gacatccgtc gtgacgccag cgcatccgtt atcttgaata acttatataa attgacatcc
    25741 ttgcaaaatt catttggatt caatatgttg gcgatcgaaa aaggtgtgcc gaaagttttg
    25801 agcttgaaac aaatccttga aaactatatc gaacatcaac gcgaagtcat cacacgacgg
    25861 acggtctttg aaaaagaaaa agcagaagca agagcacaca tcttagaagg tttgcgtatt
    25921 gctttggatc atatcgatga aatcattgcg attatccgcg ggtctaaatc agatgacgag
    25981 gcaaaagcaa caatgatcga acggttcgat ttatccgatc gccagtctca agctatttta
    26041 gatatgcgtt tacgccgatt gaccggtttg gaacgggaaa aaatcgaaaa tgaataccaa
    26101 gaactcttaa aactgattga agatttaact gacattctgg caagaccaga acgtgttaca
    26161 gaaatcatca agaatgaatt agcagacttg aatcaacgat ttggtgataa acgacgcaca
    26221 gaattactag tcggtgaggt cttaagtctg gaagatgaag atttaatcga agaagaagaa
    26281 atcgttatta cattgacaaa caatggttac atcaaacgtt tggcaaataa tgaattcaga
    26341 gctcaacgaa ggggtggacg tggtgtccaa ggaatgggta tccacaatga cgacttcgtc
    26401 aaaaatctgg tttcttgttc tacccatgat acattgttat tctttacgaa taacggaaaa
    26461 gtgtatcggg caaaaggata cgaaattcca gaatacgggc gtacagccaa aggaatccca
    26521 atcatcaatt tactaggtat cgattcgagt gaaagcatcc aggcaatcat tgcggtgacg
    26581 ggagaagcag aagaaggcca ctatctcttc tttacgacgc gtcaaggtac agtaaaacgt
    26641 acttctgtca ctgcttttgc taacatccga agtaatggtc tgatcgcaat tggtttgaaa
    26701 gaagacgatg agctcgtcaa tgtgctactg acagatggtc aatctaatat cattattgga
    26761 acacataacg gctactctgt cactttcaaa gaagaagcag tccgcgatat gggacgtaca
    26821 gcttccgggg tcagagggat acgcctgcgt gaggaagatt atgtcgttgg ggcagcctta
    26881 atgaaggaaa atcaagaagt attagtgatc acagaaaaag gttacggaaa acggacaaaa
    26941 gtatcggaat atccagtgaa aggccgcgga ggtaaaggga tcaaaacggc gaacatcact
    27001 gaaaaaaatg gtccactagc tggattgacc actgtttctg gagatgaaga catcatgctg
    27061 attacagata aaggtgtcat tatccgtttc aacgtatcga ctgtttctca aactggacgt
    27121 tcaacattag gcgtacgttt gatgaagatg gaagctgata cgaaagttgt cacgatggca
    27181 gcagtcgaac cagaagctgc agaacaaaca gttgaagaac aaggatcaga agaataacca
    27241 tcaagactaa gtgtgtaagc tagcaagaat aaccgattaa aaaatctggt tattcctgct
    27301 ggcttttttg attagttgaa tttctcttaa aatattcgaa actgttcatt ctgtattgct
    27361 tttgaccaaa atagagtgta taattagagc ttgtgagtag tctaattaat tagataactc
    27421 tccttgctct taggaaccta agagccgaaa gtccacaggg aggtgaatat caatggaaaa
    27481 cacgaaatat gaaatcatgt acattattcg tccaaacatt gatgaagaag caaaaactgc
    27541 tttaatcgaa cgtttcgatg caatcttgaa agataacgga gcagaagtta tcgaatcaaa
    27601 agattgggaa aaacgccgtt tcgcttatga aatgaacggt taccgtgaag gtatctatca
    27661 catcgttaaa gtatcttctc catcatcagc aaatgctgtc aatgaatttg accgtcttgc
    27721 taaaatcaac gacgatatca ttcgtcacat gattgttaaa gaagaagctt aattgttgtt
    27781 tcatgtgaaa caatagaaaa cgatgagagg agatgactat tttgattaat aatgttgtat
    27841 tagttggacg tctgacgaaa gatccagatt tgcgttacac agcaagtggt acggcagtcg
    27901 caacatttac tttggctgtg aatcgtaatt ttacaaacca aagcggcaat cgcgaggctg
    27961 attttatcaa ctgtgtgatt tggcgcaaat cagcagaaac tttagcaaac tatgctcgta
    28021 aaggaacact tttaggtgtt actggacgta tccaaactcg ttcttatgat aatcagcaag
    28081 gacaacgtgt atacgtgaca gaagtagtag ctgacaactt ccaattgctg gaaagtcgtt
    28141 ctgcatctga aaatcgccaa caaagcggcg gattccaaag ttctggtcaa tcagctggcg
    28201 gatttggcgg aaacaataac tctaatcaaa catctcaatc atccaacggt atgcctgatt
    28261 tcgaccgtga tacttctgac ccattcggct caagttcaac gatcgacatt tcagacgatg
    28321 atttaccatt ctaaacgaat ttgataggag ggaaatagaa tggcacaaca aagaagaggc
    28381 ggacgtaaac gtcgtaaagt agactacatt gctgctaacc atattgaata tatcgattat
    28441 aaagatatcg aattactaaa aagatttatt tcagaacgcg gtaaaatctt gccacgtcgt
    28501 gtaactggta caggcgctaa aaaccaacgt aaaattactg ttgcaatcaa acgcgctcgt
    28561 atcatgggct tgctaccttt cgttagcgaa gactaataaa tcctaggaat tgaatgactg
    28621 atccttttga tcagctattc aattcctttt tttctgtaaa aataacctct attcgtttag
    28681 tcgctcgaat gacgaaagtt atggtaaaat caaattagtc atatatggga ggaaaattat
    28741 ggaaaataaa aacaatcatt tatccccgaa acctctcttc cttatcctgt ttatattaat
    28801 cgaagtattg gtagtcttaa ttttaccatt tcgttttgtt agcgcttcgg tcattctatt
    28861 gatgaattta tggggtgttc gctattggtt gaaaatgaaa cgttggctta ttttaaataa
    28921 acgtgaaaaa atccagcagg cttcgactgt agctgaaacc aatctagctt atgtctcaga
    28981 agtcatgcct gtaggagtga ttgcttatca gccatcaagc caaaaaatcg aatggctcaa
    29041 tccattagca ttgaaaatca aagatcaaag tggattaaca gaggaagaat tgctagatac
    29101 tttttttact gcaaaagaaa aaaagaaaaa ccaagtctat ctagcagata aaacatttca
    29161 gtttgatatg gatacagtaa agggtgttgt ttattttaat gatattaccc aaaaccagtt
    29221 gttaaaactc catcagacga acagtcagcc ggtgattggt attttatcta ttgataacta
    29281 tgcagatgcc attgataaat tagatgacaa agagatttct tatttgaact ctttcgtcac
    29341 tacactagtt tctgactgga tgaatgaata ccatgtcttt ttcaaaagaa tcaacgcaga
    29401 acggtttttc ttcgtagcac agatgatcga tctgaaaaag atgatggata aaaaatttga
    29461 tttgctggat cgctttcgag cagaagctga aaaacagagc tcgcctatca cccttagtat
    29521 ggggattgct tatggctcaa gaaccctcga tgaaatcggt ggagaagctc agaataattt
    29581 agatgttgct ttagtccgtg gaggcgacca agttgtcgtg aaagaggtaa aagaaggagc
    29641 aaaacctgtt tattatgggg ggaaatctgc taagaatgtc aaacgcacgc gtgttcgttc
    29701 tcgagcgatg agtaccgctt tgcgtcggat ttttgatgaa acaggcgatg tgtttatcat
    29761 ggggcacaag tttccggata tggatgcttt aggctctgct tttggtgtca gttgtctggc
    29821 acgcttcaac cagaaaaaag cttacatcgt tatcaatgag aacgagatca ttccagatgt
    29881 agaacggtgt cttgaagaaa tccataagca tcctgaatta gaaatgcaac taatctctcc
    29941 agaacgtgcc atagagctga aaaaagaaga ggacctcctc gtgatggtgg attaccataa
    30001 accttctcta tcgatctctc agggcctata tgagcaattt gataagattg tgatcattga
    30061 tcaccatcgt cgtggggaag agtttccaag taaacctctg ctgacttata ttgaatcttc
    30121 agcttcttca gcttcagagc tagtttctga gctgatccaa taccaaagca gcaaaacaaa
    30181 tcgcttagat cgttttgagg ccacattatt gcttgcaggg atggttgtag atacaaatag
    30241 tttcaatgtc cgtacaactg cacgaacttt tgacgttgcc agctatttaa ggtcttgtgg
    30301 agcagacgca tccttagtac aatatttatt gagctcggat ttagcgacat acttggagat
    30361 cagcaatttg attgctggaa gcgactatgt gacttctgat attgttgtgg cggcagggac
    30421 agacgaaaaa gagtataata gtgttatagc agcaaaaaca gcagatacat tgctttcgat
    30481 gatcaatatc aatgcagctt tcgtcattac aaagcggaca gacggcttga ttgggatcag
    30541 tgccagaagt accggcacga tcaacgtcca aatcatcatg gaatccttag gtggcggagg
    30601 acacttcaca aacgcagcta ctcaactgga aaatacgaca gttgaggaaa caaaacagaa
    30661 gctatttgct gcaatcaaag aaaatatgaa tcaaatatat gataaggagt aatccaaatg
    30721 aaagtaattt ttttacaaga tgtaaaagga aaaggtaaaa aaggggacat caaagaagtt
    30781 ccagcaggtt atgcacaaaa ttatctaatc aaaaataact tggcaaaaga agcaacgaaa
    30841 agcagtatca gtcagttagc aggacaaaag aaagcacaag aaaaacacga agctgaaatc
    30901 ttggaagaag ctaaaaagtt aaaagaattc ttggaaaaag aagatactgt agtcgaattg
    30961 aaggcgaaag caggggaaga cagccgtttg tttggttcga tcccttcaaa acaaattgct
    31021 gaagggttaa acaaacaata caaaatcaaa ttagataaac gaaaaatcga attagaaaat
    31081 ccgatccgtt cactaggcta cacaaacgta cctgttaagc ttcatcatga ggtgacggct
    31141 acgatcaaag ttcatgtcgt acaagaataa caaatcttga tagcgatgtt cagctggtaa
    31201 gtataaccag aaggaaaaaa gacaaaccga aatttatctg agaaaacagc tgcagcaatg
    31261 aaagcaaaag ctgcaaatcg atttcagatt gatttcggtt tcttttttgg gaacagcaaa
    31321 atagcataaa gaaaacgagt ataataaaag agaactattt ttttattaca ctttcggtac
    31381 gaatgatgac ttttctctca ttttcttgta aaatgaagca attgaagaca aggagcgata
    31441 cgtatgaatg aagtgtggca ggatcgaatc ccaccgcaaa atattgaagc tgaacaagcg
    31501 gttttaggct ctgtttttct tgacgcagaa acgatcattg atgccatgga gtacatagag
    31561 ccaaaagact tttatcgtcg tggccatcaa attatttttg agacaatgat cgagttaaat
    31621 gatcgtaatg aagcgattga cgtggttact gtcaaagacc ggctggaaca agccaatttg
    31681 ttagaagatg ccggtggttt aagttatctc tcagacttgg cattagcagt tccgacagca
    31741 gcaaatatcg tctactatgc gaaaatcgtt gaagaaaaat cattgctgcg tacattgatc
    31801 cagacagcaa caggaatcgt tacgaaagga ttcgagcaag gagaagaagt tcaaacaatt
    31861 ttagatgatg ccgaacgcag tatcttggag gtttcggaaa aaagaaatcg aagcggcttt
    31921 ttatctattg ctgaagtact gaactccacg attgaaaata tcgatcgact agctcaaaac
    31981 aatgaagaaa tcacaggtct accaactggc tatcaaggtc tggataaaat gacagcaggt
    32041 ttccagcccg aagaactaat cattcttgct gcacgtccag cggtaggtaa aacagcgttt
    32101 gcattgaata ttgctcaaaa tgtaggaaca aaaacagatc gttctgttgc gatatttagt
    32161 ttggaaatgg gggcagaatc tcttgtaaat cggatgcttt gtgcagaagg ttcgattgag
    32221 gccagccatt tacgtacagg tcagctttcg gaagaagaat ggtcgaatct gatcgttgcg
    32281 atggggagtc tttctcgagc aaatattttt atcgatgata caccagggat caaaatctct
    32341 gaaatccgtg cgaaatgtcg gaaactagcg caagaaaaag gcaatctagg cttgatattg
    32401 atcgattatt tgcagttgat tgaaggtaac ggtaaagaga accgtcaaca agaagtatca
    32461 gatatctctc gccaactgaa aaaactggcg aaagagctga aagtacctgt cattgctctt
    32521 tcacagttat ctcgtggagt agaacagcga caagacaaac gaccagtgct aagtgatatt
    32581 cgtgaatccg gatcaattga acaagatgcg gacatcgtag ccttcttgta tcgagatgat
    32641 tattatgaaa gagaaggcgg agatgacgat gatggaaacg agccaaaaaa tgacaacgtc
    32701 atcgaagtca tcatcgagaa gaaccgaagc ggtgcacgag gaacagttga actactgttt
    32761 atcaaagaat acaataagtt ttcgtcgctt tcgccaagag aagaatttta aagaagaggt
    32821 tgtgagcctt gagcaatccc gagagctctc gtaagaagat gcaaggagta accgcaggaa
    32881 cgactagagt acttaattta aacagatctc caaagggatt gtgacaaaag tcttgtcaca
    32941 gtcccttttt ccgaataaac ggtgttcaat cagctgaccc ttggtattag ctcagcaaac
    33001 gtcaaaatat gaggaactat tttgacgttt gtttctctaa tactcaggtc aaaacgctga
    33061 tcttacgacc tcttttcctt aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca
    33121 atatcatcaa acatgagaag cagttttttg aaattgctcc ttgtgactca gagttaaacg
    33181 gcaggctcac aacctctttc ttaaacggtg ttcaaaagct tgcatctgcg gtaatacgcc
    33241 caatcaaacg aaaaatatga gaagctattt ttgtttggct gttcttatta cttgatgcag
    33301 gacagctttt tcacaacctc tgattcacgg tgttccaaaa gtagcttctt cgaaaaataa
    33361 gtcgaaattt cacaaaaatt tgagaagcaa ttttcgtaca ttccttctta tttcttgaag
    33421 ctgaccactt ctgttacaac ctctttttta ataaccattc taaaaagata aagttcgttt
    33481 tttaagcgtt tttataaaat aaaaataaaa atcattcgat tttatttgaa atatgtatct
    33541 attattgata caatggttca ggattaaata atatagaacg aggtgttcac atgtcatctg
    33601 tagtagtagt aggtacgcaa tggggcgatg aagggaaagg aaaaatcaca gactttctca
    33661 gtgaaaatgc tgaagtgatt gcacggtacc aaggtggcga caatgcaggg cacacaatta
    33721 agtttaacgg tgtgacttat aaactgcatt tgattccttc tgggattttt tataaagaca
    33781 agatcagtgt gatcggaaac ggcgttgtag tcaatcctaa atcattggtt aaagaattag
    33841 cttatttaca tgaaaaaggt gtagaaacaa gtaatttgcg tatttctgac cgcgcgcacg
    33901 taatcttgcc ttatcatatc aaattggacc aattacaaga agatgctaag ggcgaaaata
    33961 agattggtac aacgattaaa ggaatcggac ctgcctatat ggataaagca gctcgtgtag
    34021 gtatccgtat tgcagactta ttagataaag aaatttttga agaacgtctt cgtttgaatc
    34081 tagatgacaa aaaccgtcaa tttgtaaaaa tgtttgattc agaaccactt gattttgacg
    34141 atatttttga agaatattat gaatacggac aacaaatcaa acaatacgtc acagatactt
    34201 ccgttatctt gaatgatgct ttggatgcag gcaaacgcgt gttgtttgaa ggcgcacaag
    34261 gtgtaatgct ggatatcgac cagggaactt atccttttgt tacttcttct aacccagtag
    34321 ccggtggggt aacaatcgga agcggtgtag ggccttcaaa aatcaataaa gttgtcggcg
    34381 tctgcaaagc ctatacgtca cgtgtcggtg atggaccatt tccaactgaa ttatttgatg
    34441 aaacaggaga acaaatccgc gaagtaggac gagaatacgg tacgacaact ggtcgtccgc
    34501 gtcgtgtagg ctggtttgat tctgtagtta tgcgccattc taaacgagtt tcaggtatta
    34561 ccaacctatc tttaaactcg atcgatgtat taagtggatt ggaaacagta aaaatttgta
    34621 cggcttatga attagatggc gaactaatct accactatcc agcaagcttg aaagagttga
    34681 accgctgcaa accaatctat gaagaattgc caggctggtc agaagacatt acaggatgca
    34741 aaacacttgc agaactgcca gaaaacgcac gtaactatgt acgtcgtatc tcagagcttg
    34801 ttggtgtacg tatctcaaca ttttctgtcg gacctgatag aacacaaaca aacatcttag
    34861 aaagcgtctg ggcgcaaatc taaggataaa aacgacgact gaatcaggac gttcttacca
    34921 gagcgagtcg aagtgtttat ctatacgata ataataactt gaagaggtag tgaaagagac
    34981 gtttagcctt attgccgata ggctgtctct tgaacactgt ttattcagaa taagggactg
    35041 tgacaaaaac cgtgtcacag tccctttttc cgaacaaacg gtgttcaaaa gcttgcatct
    35101 acggcactaa gcccaatcag atgaaaaata tggagtgcta tttttatctg attgttctta
    35161 ctgcttgatg cagagcagct ttttcacaac ctctccacta aacggtgttc tcctgccaac
    35221 tcctcggtca caagtcacaa tattcaacaa acatgagaag ctgttttttg aaattgttcc
    35281 ttgtgactcg gagctaaacg gcaggctcac aacctcttgg taaacggtgt tcaatcagct
    35341 gaccctcggt attagctcaa aaaacggcaa aatatgagga actatttttt ccgttttttt
    35401 ctctaatact caggtcaaaa cgctgatttc acaacctctg attcacggtg ttccagaagt
    35461 agcttctacg gaaataagcc gaaatttcac aaaaatttga gaagcaattt tcgtaaattc
    35521 cttcttattt cttgaagctg accacttctg tcacaacctc ttattttgat tagaacttgc
    35581 gaaaataaac cggttaaagt gtgtctagcg caagagattt gctataatag acgataaggg
    35641 taaaatgtaa cgagaagggg ttgaaaaatg tgtatcaaat tgtaacagat tcttgttgtg
    35701 atctgccata ccatgtatta gcaaaagaaa aagttgattt tttatcaatg aatctccaat
    35761 tgaatgatca agagttagta gatgacctcg gaaagacatt caattatgac cgctacatga
    35821 atcagctgaa aaatggtgcg atgcctacga catcacaaat caatgttggc cgatatttag
    35881 aatttttccg ttcttatgcg gaaaaacaga ttcctgtttt atatgtggct ttttccagtg
    35941 gattaagcgg ctcttacagt agtgcgcttc aagcggttga attgctgaag gaagaatatg
    36001 aagaccctga gatctatgtt tttgatacaa aagctgcaag tattggggaa gggcttttag
    36061 tattggaagc tgtaagattg aaaaaagaag gtaaaagcat cgaagaaacc ctagagtggc
    36121 tggaaagtaa ttatttgaaa gtccattcat gggtaacagt agacgatctg aaatatctag
    36181 aacgaggcgg taggatttcc aaagcaagtg ctactcttgg cagtctattg agtgtaaagc
    36241 ctattattac ggtggataaa gaaggaaggc tgacgaatgt tgacaaagtt cgaggaagaa
    36301 acaagtcgat ccagacaatc gtcaatgaga cggtaaaaac aatcgttgca ccacttgatc
    36361 aaatcgttta tgtggcttac gctggggatc tagagagcgc ggagaaggca aaacggcttt
    36421 tggaagagca gataaagatg aaagatgtga agctttatcc cttaggacca acgatcgcca
    36481 gtcacacagg ctatggctgt atcgcgattt tttcgatggg aatcagtcga taaaagcagt
    36541 aactcattct gtaaaaaagc ccagaaattg attgtaacaa aaacagcgac tcttaaaaga
    36601 tagatgagca tcctatctct tagaggtcgc tgttttttta ttttttaagc taaataggcc
    36661 attatgccca taactcgttc aattgttttt gaatatctgc attttccaaa aattcatcat
    36721 atgtcgtatc agctcgatcg atcacacctt tatccgaaac ggcaatgatg cggtttgcca
    36781 atgtttggat aaattgatgg tcatgtgacg caaataagat tgagccagta aatgccatca
    36841 agccgtcatt caatgctgtg attgattcta agtctaaatg gttcgttgga tcatctaata
    36901 caagtacgtt agctttcgaa agcatcattt ttgaaagcat gcaacggact ttctctccac
    36961 cagataaaac attcactggt ttcaatactt cttcaccaga aaacaacatt cttcctaaga
    37021 agcttcttaa gaaggtgtta tcatcttctt ctttacttgc atattgacgc aaccagtcta
    37081 aaatcgttag atcagtatcg aattctttcg ttgtatcctt tggtaaataa gaattacttg
    37141 ttgtcacacc ccaacgtact gttccagtat ctggcgtaat ttcacccatg ataactttga
    37201 atagcgttgt tgttgttata tcattttctg cgacgaaagc gaccttgtct tctttgctca
    37261 aattaaaaga tatatcatct aaaattttct ttccatcaat cgttacactt acattttcta
    37321 cctgcaataa gtcgtttcca atctcacgtt caggtttgaa tccaacgaat ggataacgtc
    37381 tagaagaagg ttggatatcg tctaaagtaa ttttttcaag cattttttta cgtgaagttg
    37441 cttgttttga ttttgatgca ttcgcactaa agcgggcaat aaattcttgg agttctttga
    37501 tttgttcttc ttttttggca tttgcgtttg cttgaagttt agccgctagt tgactagatt
    37561 ccaaccaaaa atcataattt cctacataaa gtttgatttt accaaaatct agatccgcca
    37621 tatgtgtaca tactttgttc aaaaagtgac ggtcatggga tacaacgatc acagtatttt
    37681 caaaattgat caaaaattct tccagccaat tgatcgattg gatatccaga ccgtttgttg
    37741 gttcgtctag caaaagaaca tcaggtttac caaatagtgt ttgtgctaat aacactttta
    37801 ccttttgtcc accagttaat tcactcattt gctgatggtg caattcttca gggatgttca
    37861 gaccttgcag taaaacagct gcttctggtt cagcttccca tccattaagc tcagcaaatt
    37921 ctccttctaa ttcagctgct cgaataccat cttcgtcagt gaaatcctct ttcatgtaaa
    37981 tcgcatcttt ttctttcagc acttcataca gacgcttgtg tcccatgatg actgtttcaa
    38041 gtacagtata gtcttcatag tcgtaatggt tctgtttcaa tacggccatc cgttcatctg
    38101 gtcccatagt aacggaacct gtggaaggct gcagatcccc tgataacact ttaaggaacg
    38161 ttgatttacc tgcaccattt gcaccaatca agccatagca gtttccgggg gtaaatttaa
    38221 tattcacatc atcaaatagt ttgcggtctg aaaagtgcaa actcacatca tttacagtaa
    38281 tcaatttttt tcctcacttt tatcattatt agttttgaca agtcttatag aattatatag
    38341 gggaaaggta aaagattcaa ggcaatcgaa cattctttgt gtttcacgtg aaacagaatg
    38401 aaaaaaataa aaataaaagc ggagcgaaaa tagctactat aggatttatt agtttgcaac
    38461 agcataattt ttgacgttat ttataagagg gagtactata aaactgtaaa agaaatgaaa
    38521 gaaggattga aaatggatga aaaaagaacc atcgactggg gctcattgat tttgggaatt
    38581 ttatttgtac ttgtctcatt gttatcattt caagaccctg tcggaaattt agttgcaatt
    38641 gtagtagtct ttgcgatttt tgcctttatt aaagggatat ttgaactgtt tgtacggaac
    38701 agattaaaag agctaacagg atataaagga aagatgccct taataatcgg gatcatcgat
    38761 attctagttg gcgtcttttt cttattcaat attggtgcag gagtcgcagc attgcctttt
    38821 gtttttgcag tatggtttat tgctgattca gttttagcgt tatttactgc tgacttggca
    38881 agaggagtaa gtgaaggata ttattggttt acgatcatcg tcaatatttt aggaatttta
    38941 ttaggaattt tcttattgtt taatccaatt tcttctgcgt tgacattaag ctttttagtt
    39001 ggattctatt ttatgttatt tggtatcaca catatcgtct atgcatttag ataagtaaaa
    39061 tcaaacaaat aaaaaagccg gcttccgatt acagttttac tgttgtaatt ggaagccggc
    39121 ttttttatca tggacaaata tgcacgaggt gatttttagg tgtcgagaca aatttatgca
    39181 aaaatgtgag aagctatata cacaaatttt atcttaatac tcgaagcata gcgcagttgt
    39241 cacaacctct tttcatataa ttcattcaat actggcaaat catggacttc atatttttct
    39301 ttgaatgctt ggatttcttc ttcagaatat tttcttggat ctaaatgcag atcttctact
    39361 ggcaatgggc gcttgttatt gatcttcaca tcgattacta caggacgatc tgattttgca
    39421 gctgcatcaa aggcaaatcg aagttgcgag tattctgtga ctgtaaagct atttgccccg
    39481 agcgcttctc caactttacc gaaatctgca tcttctaaaa atacaccaaa tttcttttgt
    39541 tccgtatctt cttgttctgc ttcgatgaaa ccaaaagaat cattcgaaaa gacaacatta
    39601 ataattggaa gctgatattt gacttgtgta atgatatctt gcatgaccat agcaaacccg
    39661 ccatcaccac ttaaggtaaa tacttgtttt tctgggtagc ttagttgtgc ggcaattcct
    39721 cctggcacac cattacccat agttgcgaac catccagatg tcgtatgttt ttgtttaccg
    39781 ttcatattca ataaacgaat agaatggata gtcgtgttac cgacatctgt gacgaaaatc
    39841 gcatcgtctt cagcaatacg attgatttct ttatagacag cctctggacg aatcggttct
    39901 tcctctcgat cttcaaaaga tttcaaccaa tttacccatt tttctttatt ttcttgattt
    39961 gctaggtacc agctatcagc agggcgagca tcccctaact cgacaagtct ttgcaaagct
    40021 gtgtttgcat caccgaggat cgacaaagat gtttcatggc gtcgtccaaa ttttgacgca
    40081 tcgatatcga tttggataaa ttcagcagtt ggattaaaaa atgcacgtcc aaatgggaag
    40141 tcgctaccga caaataagat cagatcggct tctgccaatg cttcatttcc gggtttagta
    40201 gcgacacgtc cagcaaaacc aagaaagttt tcataatcat caggaataat tccttttgct
    40261 agaacggaag cgacaacagg aactgaaaaa tgttctgaga attctttgat ttgcggaaat
    40321 ccgtttcgcg ttccttgacc aacataaaga actggttttt ttgctttttc aagataaggc
    40381 aaagcagcta gcaaatcttt ttcttctggt aatatcacac ttgttttgtg agtgtgagcg
    40441 gtggagaaag gttgttcgtc aatttcttca aaaccaagat caacagggat agtcacgata
    40501 gccacgcctt tatgctcata ggcggcttta atggcttcat ctactacatg cggaagactt
    40561 tgtggtgtca tgactgtacg attgtatacg ctaacatctg cgaaaatagg attttcattt
    40621 agttcctgga aagagttata gttcatggat gtagaagcaa cttgtcctaa gaacgctact
    40681 agaggcacat ggtccatctg tgcatcatac aaaccattga tcaaatgtgt cgcaccaggt
    40741 cctgcagagc cgaagacagc gccgactttc cccgttaatt ttgcatctgc agcggctgcg
    40801 agtgcgccga cttcttcatg acgaacttga atgtagttga tttcggtttt ttcttgatat
    40861 agcgcatcca taattgaatt gaaagatcct ccgggaatgc cgtaaatatg gtcgataccc
    40921 cagctttcaa gaacttttac cattgcgatt cctgcattga tttttgacat ggtgtttcac
    40981 tcctttagca atgatgatac ataaattttt tgtatctaga gtatagaact ttttatcgaa
    41041 aatcccaact aattcgtctt ttcacaaaaa tgtagtcatg tttttgggaa tatgctagag
    41101 tagtacatag atagattcaa gagaggggaa tggcatggtt gaatggctat tgagacttga
    41161 accttggcag caagcacttg ctgggacagc ttttacttat tttatgacag ctcttggtgc
    41221 cgggttggtt tttttcttta aagaaatcaa aaaagaagtg ctaaacttga tgttaggatt
    41281 tgcttctggt gtcatgattg ctgcaagttt ttggtctttg ttagatccgg ctattacaaa
    41341 agcagaagaa aatggagata ttgcttggct agttgtaagt attgggtttg gtttaggcgg
    41401 tgtgttttta tatatggcag ataaaacact gccccatatg cattttggac cacaacatga
    41461 agcagaagga ttgcctaccc atttaaaacg gacgatcttg cttgtttttt ctattacatt
    41521 gcataacatt cctgaaggtt tagccgtggg ggtagcattc ggtgcagcag caactgcgga
    41581 taatccgaca gccgctatat tagccgctgt ttcggtggcg ctaggtattg gtatccaaaa
    41641 cttcccagaa ggagcagctg tatcaatccc gttgcgacaa gaaggtctga gtcgtaaaaa
    41701 ggcctttgtt tacggacaag cttctggaat cgttgaacca attgctggag tgattggagc
    41761 gctactagta acgaaagtgg agctgctgct tccttatgca cttgcttttg ccgcaggagc
    41821 aatgatttat gtcgtggtgg aagaattgat ccctgaagca cagcagacat tgtccagcaa
    41881 acgtcatttt gcagtttttg gcgtcatgag tggatttatc attatgatga ttttggatgt
    41941 ggcattagga taaataaaaa aaatatatat gatatatcaa atagggccgc gaacttatat
    42001 cgcgacccta tttttttagt aagttatatc ataatgaagt gaatggtatc atacattaat
    42061 aatagttttt tctatgtgta tttcctttga tccagcgaac aagccagatg ataagtgcga
    42121 ttgggattag aactttgacc gcaaaccata aaagcccgct taggacactg acaaaaagac
    42181 tgatgacgaa gctagctgca attagcacta aaagaaccat gaagatattt aagaacatat
    42241 ttttttgacg catacaaaac cctcctcttg ttcattcttt actatagaaa aagtataaca
    42301 gggattgttt aaaaacacct ccaactgaag actgattttt acttcatcta cttaaatgat
    42361 caaacaattg ctttttctct ggtttatcat ctaaaataga gcggaaaagg aggagaatat
    42421 catgcctaaa aatcgtcttg aagcatttac agatgctgta atcgcgatta tcatgactat
    42481 tttagtttta gaacttcatg aacctaacgg agacacgtgg gaggcgctcg ctgcattagg
    42541 ttaccgattt tttatctata ttgtcagttt tatcatttta gcgatttatt ggaacaatca
    42601 tcatcattta tttcaagttg tacataagat aaatggacgg gtcttatggg cgaacagttt
    42661 ctttgttttt gcgctttcgc tttttccgtt tgcaacttca tggatcagtg agtacatcaa
    42721 tagcctggct ccagaaatga cttatggttt tgttaccttg accgctaata ttgcgtatta
    42781 tatcttggca aaagaacttg tcaaagcaaa taaaggccac gagaaagcat tgaaggcgat
    42841 gttgaataat tacaagaaat cgtatctatc gattggtttg aatgtgttag gaattgtctt
    42901 agggtattta gtagcgccag tagccgtgct gatcgcaaac atcgtgattc tagctgcttg
    42961 gatcatccca agtcgtacca tcgaatcaca atatcggtaa aatgatccgt gtttaaaatt
    43021 taagagaaaa atatagaaaa aataaataaa cgatcaaata tccgagtgat actagtattc
    43081 aaagagggat gcagatggat caaaaaagaa ttcatgtagg actgattact agttttgtca
    43141 cgatgcttat ttatttggat caaggtcatt tgacttggac agtagttggt gtcgtaggat
    43201 ttttgacatt attcacagca ataaaaaaat aaacatcttt atgtaatctg atgttctatc
    43261 tatttaagaa aagcatgttt acagcagtat gattctgttg taaacgtgtt tttatttgtg
    43321 gaaaatttaa tttttagaaa agtgtatcga aaaatagata gttagttttt ccacagtgga
    43381 taacttcgta agagataaaa ataaaaaatt agtcaaagaa gggcgtatag atttcttttg
    43441 ataggagata tacaacagaa atgaataaat attaacgtgt tttcaaacag tataaaacgg
    43501 tgtggttttt ggaataaaaa aataacatat ctcattttac gcttttgtta ttttatactt
    43561 aaaaaataac gacacagaaa ataccgtgtc tcagatttct ctactacttc taaaaactac
    43621 tgtttttttc ctttgaaatg ccttcaaaaa gtaggatcag gcagaatata ctggcagaat
    43681 caaggagaag ggagcctaaa taaggagaaa aaccatagaa aatataaagt aattacttat
    43741 aaaacaagct ttttatagaa aaataatata cctgagtagg gtataaatta agacggaatt
    43801 cctttctaga ttgagatatt gactaggaag aatgttaaga ttttaagcct ttaagctaaa
    43861 aaaaaaccct ttttgttaaa taaggggaat atagcctgtc agtttcaaac tgcaagtcgt
    43921 cctgctgcaa taatatagta gattagagat gaaaatagat ttttttaaac caatgactga
    43981 ataaaaagac cgtcatagat acacattgga atgtgtctat tacggtcttt ttttacgaac
    44041 gattttattg aagacggaca gttcgggtca aaaataaaaa agctacgatc agaaataaga
    44101 ataaaatgta tcccaaaata atggctagac ggtctaactt atttgtcgat agatgtttgt
    44161 ttagaagttg ataggcccat aaacctatca gtcctcctgt tgtattagtt atcaaatcag
    44221 tgatgtccgc tacgccaata ccgaatagga attgaatcaa ttctgccaag aagcttacaa
    44281 ggaaaataat ccctaatttt ttagaaaaag aaagtctctt gaaattgaca ttcaaaagca
    44341 ccccaaaagg aaaaaagaca atcaagttat aagtggtctc acgtaatacc gtcgtatttt
    44401 caaaagaaaa agtagaaaaa gggacgagat tgacattgct gtaagaataa gtgagaaatt
    44461 gtggaagatt aaatgatagc ttgaataaaa tcaaccataa tagaaagaat aaataaatcc
    44521 ctaataaaaa ttttgataca taccgcatag acatctcctc catttaaaaa gtataccatc
    44581 gaaaaccgct gaaaaatcat aaaaaagtat gaagtttaag gaccaacgta gttatcgtac
    44641 gaaaattaga agcttttttt tgttgggaat ccggtttctt taacaaagct aagatagcga
    44701 gttgcttgga aaagttgcta tcttttttct gtcaaaacga ctcggaatgt tcgttttttg
    44761 ttctaatttc tccaagttgt ttactttttg atactaagtt tatgaaaaat caagaaatag
    44821 ttgttatact aggtaatgct gacaaacggg attggcattt catcttggtt cagctttttt
    44881 tccaattact aggaaggagg gatagattgt tcaagactta ttttcgtttc aataaaatac
    44941 aagataatcc ttttcgtatc atgaatctga tgctacttat ctttattgta ttatggttag
    45001 gttacataaa tcatgatttt ttgatttcaa gtttttcatc attagggatc tttacttttt
    45061 tctattatca aaacataccg atgaaatatt tgctgaaacg tatgtttctg atcggttgcg
    45121 gactgttggt tgctttcgtt ttggggatct tatcgactta tgttttatgg cttgaaccat
    45181 ttgccgtagc tttggttgct ttttccagca gattcgtgtt gcgattattc catatttcta
    45241 aaccaggtgg cttgtttttt gcgatgcttt ctgccatggg aacgagcatg cagctgccaa
    45301 tcgctcaatt accgatcgtc tcactttatt tttttatggg tgtcgttttt gccctgattg
    45361 cggcagtgat tacaaaatta ctggattcac ggcctgagca gacaattgaa aaagcaactt
    45421 taaaagaaag atttcacgaa gagcctttag tgatcattga ttctgttttc tacagcgctg
    45481 ccttatttct ttccgtttat gtcagtcacg gcttgaatct gcataatcct tattggttga
    45541 ccttgtcatg tgcatcgatt ttgctagcag aaaacttgga tgcgatgaag catcgacaag
    45601 tccaatatct gattggatcg atgggtgggt tatgtgtgtc ggcattcttg tcatttgtgc
    45661 cgtttacgca gttgcagacc atttttctga tcacttttct atatggaatc gcacaatttc
    45721 tagttgctag aaattatgca gttgctaata tttttcttaa tccgatggcg ttgatgctat
    45781 ctacacttat tcgtggagca tacttgattt ctttgatcga atatcgtttt ttagggatcg
    45841 tcataggaag tttcatcggt ttaggtgttg cgtgggtaat gacggttggt ttgcaacatt
    45901 atttaacggt tgttcgtcaa aaattagaat agaaggacaa atatatgtgc caaaagaggt
    45961 tatgacaaga tttttgtcac aacctctaat tcaaggtgtt caaaagccag attctcagca
    46021 ttaagtcaaa ttcacacaaa aatgtggaaa ggaactttca aaaaaatttt atatttattc
    46081 tatcaaaaaa ttttatattt attctatcaa aaaattttgt ttatgatggt aactgaataa
    46141 actttcctga gatggtcaat gctttccttg aaagtcttac agatattctt tcttcataga
    46201 aagtttaagt tttatagtta gtgtacaata aaagtatgtt tataccatat ggtgtccgga
    46261 taatcagtca tttaaacaat gaggttcaaa gatatgaaaa ggggaaattt gatgaagaaa
    46321 ataagcaatg aaatccaaat tctggcagaa actttaactc ttcccaaagt cgttatagag
    46381 caaatgattg tacaagcaaa aaacatcctt gatgaggtgt ttgagcaata tagtcatgaa
    46441 ctaatggatc ctaataaagc aaaggcgact gcaaagaaaa tagacaaagt ctatgaagag
    46501 gaaccttttg cagcattagc tatttatcta tatgcagctt ctcaaagttg gaaaaaaatt
    46561 tatcaaccat tgaagattcc aagaactatc tatttggcaa caatgaatgc ttttactaga
    46621 tttattcatg aacatttcca agtaacagga agctatcgct ttgaccgtgg tttttggatt
    46681 tggcattaca ctagtggctt gatctttcgg attggtgaat tggagtacga aatgacatat
    46741 tttccgaaag ggtacacgga tctaagatta gaaggaaagc agtgcctttc tcttcatatt
    46801 ccttccgatg cagatttatc tcagaataag ataagagata gttacgaaag tgccattcgt
    46861 ttttttgaac tttattttcc tgattaccat taccaagtga tgtacacaga tacttggtta
    46921 ctatcaccca atcttactaa atggttgaaa aaagagtcaa aaatctgtct ttttgcagcc
    46981 gattatcgat tattatcagt tgatgaacag gacgatagtg gagtcccttg gatctttgga
    47041 cgagtagatg cccaaataca tgattatcca gaaagtacga gtttacagcg acaagcaaaa
    47101 gagcaattgc ttgcaggcga gcacattggc tctggcttag gtattcttac ttcataagtt
    47161 tagtacttcg aaatagttta aaagagcgtg agacaaaagt aaagaacact tttgtctcac
    47221 gctctaaaca cgtataaacg gcggaagcag aagcaactcc ttcggaaata agctgaaatt
    47281 cacaaaaatt tgaaaagcaa ttttcgtgaa tttcttctta tttcttggag ttaaacgctt
    47341 ctgtcccagc ctctttttta gtgttctatc gaacacacag tacgttcaat aggtaaacta
    47401 gctataacaa tagatattaa agttaacgga caagagggcc ttttttaggt agctaaaacg
    47461 taataatgaa aatttatttc cagagatagg agtcaatcag ctagtctgat cgactgtttt
    47521 aacaagttga ctttcatttt aacttttgat accatttaaa acacaaatcg taattgtttc
    47581 gatttgtgtt ttttagcatg actacaatca aagaagaaag tgggtcgtcc atatggaaaa
    47641 aacagatatc tcaagtgcat accgccgctt gaaaagccca aatatcaaaa cacgaaaacg
    47701 tgcgctgaag atcatcaaag atgtgaaacg gaatagtggg aaaaggtaag aagaaggaaa
    47761 cttaattaaa aaaatagccg aaaaacgttt ttcggctatt ttcaataatc ggtttttgtg
    47821 taaggtttcc gaaagaactg ctgttgattt tccattttta acatatgata aattggtaga
    47881 atctttcttt tcaaattgat accattccct aattccagtt atatagttaa ctacagaacc
    47941 acaaagcacg tacgtttata aaagtattat ctgtagttat ttttcaattc cctttcaacc
    48001 tcttattttg accagtagta ttgatcactt taccttttaa cacctttgtt cgtttttgaa
    48061 acatttttag tcaagaatgg aaacgtaact acataatcaa aggttttgcg aaatatttca
    48121 tgaaatattt catgtagaag cgagcaatac ggttgcaaat aaccattatc gtttaataag
    48181 cagttacgaa agctcccaat atctctaacg ttcagctcac tccatttctt ttcttcaaaa
    48241 aaatcagtga ttcgtatctc tttctatttg tcgaaaaagt taactttaaa aagtaacgcc
    48301 gaaaaaatat gcaaaaaaat aaaaaagcag ttactattgc tagaataaca tcaaggaata
    48361 ataagttttg gttttcagat aatagtcgat aagttgtgta ttggaatttt agatacagta
    48421 ataaagtatt tttcatgaaa ttttgtgaga atcactatta caagtatctt taataaaatt
    48481 aatggttaag gaggaactta aagtagaatg taaatgaata gttgtagtca gtcgattgtg
    48541 atactagact caaagttgca ggaataagtt tttcaatttg tgattggaag ataaaaaatg
    48601 aaaaagaagg gctttttttt atactttgtt gattgtagtg tttattttcc ctctgtttag
    48661 ccaagtaaca ttttctatga ctcaaccagt ttcaagtgag gaacatgata acctttttcg
    48721 tgctacagaa gagtttaaga aatatcagga aaatattgtt ccggagactc cattagctag
    48781 tgagccaatt actgatattg atggaaacca aataggatgg tatatacagt acgaagttat
    48841 ggtggtaaat aatgactcaa tagtaaaaaa tacagtaggc ttagagctaa caccgattga
    48901 aaaggtgagt tcattgttaa cgtatattta tactgatgaa agtgacgaga ctgagatcat
    48961 tttaacggat tactcaaaaa ttgctactga taaaaagtat atattgtgga tgtagacact
    49021 agtgaaatac tttatgatat agaaattgat gaaaatttac tagatgtagc acaagaaatc
    49081 gatcatcaaa agcaggaagc tattcgatat gctggtagaa aagggaaaag aaaatattta
    49141 ttacgtgaat gtagcaaaag ttagagaaga tgaaaatgag tggaaagaat tcaagagtcg
    49201 ctactcaatt aactcgactc cgacatttac agtttacaga gaaggatcga tagaaaaaac
    49261 tgttttttgg actaaagaaa gtggaatgtc tttagctgaa gtagaagagt ttttggatta
    49321 tgttagtatg caacagtaag ggagttctta ttatgaaaaa ttttgacaca tattatgtta
    49381 ttgttttttc gatatctttg ctgttaatat tactaacttt aatgcagtat aaagagtatc
    49441 cagagtattt tattttaact tttgtatatt tagtaagtag ctacacactt ctatataaat
    49501 tcagaagttc ttctagagtt tctaaagttt gtttcttaat tagcttattg attctataat
    49561 atttttgatt tatataggaa attaaaaata ttatagaatc aacactcaga gaacgggttg
    49621 gtttttaata gatttaataa gtactgataa tgaaatttct cctggttggg aaaacgaagt
    49681 ttcccaaaca aaaggatatt aagaaataac ctgtgtttac ctgcttgcaa attattgtat
    49741 tttggataag caagagaaaa actttttatt gacagaaata atatcaaata ttataattgt
    49801 ccgtaattga ataactatct tcagggcagg gtgtaattcc ctaccggtgg tacagcccac
    49861 gagccgaaag gcatgatttg gtgtaattcc aaagccgaca gtatagtctg gatgaaagaa
    49921 gataaaagta agtttatgct tttttgcgtg ctctggaatg attttatatt gtttcagagc
    49981 attttcttta atcgcataaa tcctcttttg catgtcttgg atagatttta ttcaaggcat
    50041 gtattttttt ggaggtgtaa aaatgagcga tatagaatac atgaaaatag caatagaact
    50101 ggcaaaaaag ggtgctggct atgtcaatcc taatcctatg gttggagcag taattgtaaa
    50161 aaataatcgg cttataggac agggatacca tgaagttttt ggtggattac atgcagagag
    50221 aaatgcacta aaaaattgca gagagtcacc tgtaggagca acgctttatg taacacttga
    50281 accatgctgt cactatggta agacaccacc ttgcacagaa acaattatta aaagtggtat
    50341 tacaagggta gtcgtcggaa ctttagactg taatccgatt gtgtctggaa aaggtgtaaa
    50401 gcaacttgag gaaaataaca ttcaagttga tgtaggcatt ttagaaatag aatgtcaaca
    50461 gttaatcaaa gtatttagga agtatattac aaagcgtatt ccgtatgttt ttatgaaata
    50521 tgcaatgaca atggacggga aaatagcaac ttatacaaat caatcaaaat ggataagtgg
    50581 cgaaaaagcg agaaaacaag tgcaccaatt cagacataag gttactgcaa tcatggtagg
    50641 agtaaatacc gttattcaag ataacccttt actgacatgc cgattagaaa acgggaaaaa
    50701 tcctattcgt atcgtatgtg atacagattt aagaacaccc attacatcaa aaattatcca
    50761 aacagcgaat gacattaaaa catatatcgc tacttcttct attgatgaaa gtaaaattgc
    50821 tctttacaga aaatgtggtt gtgaaattat ttatacgaag aaaaaaggta atcatattga
    50881 cttaatgaat ttaatgcaat gtttaggaaa tatgcagata gacagtctgc ttttagaggg
    50941 tggaagtgcg ttgaattgga gtgctcttga gcaacagatt gttgatgagg tacaaactta
    51001 tatagcacct aaaatatttg ggggtagtgg aaaaagccct gtaagtggtc aaggtgttgt
    51061 ttttcctaaa gacgccatta tgctcaaacc atatgctttt tctcaagtgg gaaacgatta
    51121 tctcatagaa agtgaagtga tttatccatg tttacaggaa taatagaaga aatcggtaaa
    51181 gtagaaagaa tacagaaaga tacttataac tgtaaactat ccattaaatc ttcaaaaata
    51241 ttagaggata tacatttagg cgacagcata gcagtcaatg gtatctgcct tacagttact
    51301 tgtttcacac gacaatcttt tatagttgat gtgatgaatg aaacatggaa cagaacggct
    51361 cttaacctgt taaaacatgg aagccttgtg aatttagaaa gagccatgca tatgaatggc
    51421 agattgggcg gtcacattgt tacggggcat attgacggga caggcagaat atcgtctgtg
    51481 cgtagagaca aaaatgcggt gtggtatcaa atcaatacgc aaagagaaat cttaaatcta
    51541 attgttgaaa aaggttcggt tactattgat ggtattagtc ttactgttgc aaaagtatcg
    51601 aaagcagatt tttcagtatc cgttatccct catactttgg aacaaacaat tctcaagaat
    51661 aaacaagtcg gggatatggt aaaccttgaa aatgatatat tagggaaata tgtgaagaaa
    51721 ctcataggaa acagcaatga aacagagttg tcgaaagagt tgttatgccg atacggattt
    51781 tagcagaaag gataaaggaa ttatgaaata taaaaaaata aaagaggctt tgcaggcgtt
    51841 acaagaggga aaacttgttt tagttatgga cgataaagag agagaaaatg agggggattt
    51901 aatttgctcg gcacaatttg ctacaacaga aaatgtaaat tttatggcga cttatgcaaa
    51961 aggtttaatc tgtatgccta tgagtgaaag tctggctaac aggcttatgc tttcccctat
    52021 ggttgaaaat aatacagata accatgaaac tgcttttaca gtttctattg attataagga
    52081 taccacaaca ggtatttctg ccgaggaaag aggattgaca gctcgtatgt gtgtggttga
    52141 ggatataaat ccctttgatt tccgtagacc ggggcacatg tttcctctga ttgcaaagaa
    52201 cggaggtgtt ttagaaagaa acggacatac ggaagcaacg attgacttat tgaggttggc
    52261 aggattaaaa gaatgtggct tatgttgcga aattatgaat gaaaacggga aaatgatgag
    52321 aacatctgat ttaattcaat tttcccaaat acaccatata ccaaccctca caattaaaga
    52381 attacaggaa tacagaaaag tatatgacat gcttgtagaa tgtgtttcag ttgtagaaat
    52441 gcctacaaaa tacggggatt tcaaagcaca ttgttatatc aataaattga atggcgaaca
    52501 tcatgttgca ttggttatgg gagagttaaa tagtggaaat gatgtgctat gtcgtgtcca
    52561 ctcagagtgt ttaacaggag atgtctttgg ctctttacgc tgtgattgtg gacagcagtt
    52621 agatagagca atgaaaatga ttgcagaaaa tggttctggc gtattgcttt atatgcgaca
    52681 agagggacga ggtatcgggc ttgtcaataa actaaaagcc tatcatttac aggataaggg
    52741 tatggacaca cttgacgcca accttgcact aggatttcaa ggcgatttaa gagaatatta
    52801 tattggagca cagattttaa gagatttggg aataaaatca ttgcatttac ttacaaataa
    52861 tcctgataaa gtttatcagt tagaagatta tggaatgcaa atttcaagca gagtaccgat
    52921 tgaaataaaa gcaaatcctt atgatagttt ttatttaaag acaaagaaag accgaatggg
    52981 acacattttg aatatggagg aaaaatagat gaacactttt gaaggaaatt tagtagcaga
    53041 aaatataaaa attggtattg ttgtagcaag gtttaatgaa tttataactt ctaagctatt
    53101 agcaggtgca ttagataatt tgaaaagaga aaatgttgat gaaaaggaca tagaggtagc
    53161 ttgggttccg ggagcatttg aaatacctat gatagcgtct aaaatggtaa aaagtaaaaa
    53221 atatgatgca attatctgct tgggagcagt tattcgaggt agtacaagcc attatgatta
    53281 tgtgtgtagt gaggtatcaa aaggaattgc tcaaatcagt ttaaatactg aaacaccagt
    53341 tatgtttggt gttcttacga cagatacgat tgaacaggcg atagaacgag ctggcagtaa
    53401 ggcaggaaat aaaggctctg aatgtgcaca gggagctatt gaaatggtaa atctaattcg
    53461 tgcattagag gtataatgtt gatcagcaca ttataatatg ccattttcag agaaataaat
    53521 agtgcagaaa taatacgggg atcttccatc cccgaacccc tggaatcctt gttataacag
    53581 taatagaaaa aattattacc gttataacaa ggctaaaaat gggatgtttt aattttccga
    53641 attctgcaaa ttatggcatc aaataaaatg cgttgtaaca gtataatatg cttggggtta
    53701 aaagctaaag cgaaaaaaca taacaggcgg agtgatccag acacgacggt gggaaaatct
    53761 cttagatttt tccgccgttt ttagtggctg gttcacttcg gcagttgagc gagcttgcga
    53821 gcgaacagta agcccccgtt atctaacaag gggggcacaa aaaacaagag acaatagaca
    53881 ctactaagcg gaaaacgctg tatttacaag gcaaaaccgc ttttaacagg gtgttaacta
    53941 aaagacactc atttaacaca taaaattgaa taagacatag gaaagacagt tgatttcaaa
    54001 tgaaaaattg attgtctttt tcttttgaag aaatttaagt atagacaatt atcagtaaat
    54061 ggtagttgtc ttttttgatt ggaggaattg aagaatgaat gataagaact ttatagaaga
    54121 attaagacaa aagcgtgaag aatacggagt aacacaaaca agaattgctg ttgcctgtgg
    54181 tatcagtcgt gagtattata accgcattga aaaaggcaaa cagccattga ataacgaatt
    54241 aaaggaaatc atagaaaaac agattgagcg tttcaatcca cgagagccgt tatttttact
    54301 aattgattac tttcgtgtcc gctttcctac tacggacgca ttaaagatta ttcgtgatgt
    54361 attacaacta aaagccgatt atatgcttta tgaagatttt ggaaagtacg gatatgaaag
    54421 taaatatgtt ttaggcgaca ttaacatcat gtgttccatg caagagcatt taggtgtttt
    54481 gttggaactg aaaggcagag ggtgtcggca aatggaaagt tatctcttgg cacaggaacg
    54541 ctcatggtat gactttatgc ttggttgtat gacggcaggc ggtaagctga aacggcttga
    54601 cttggcaatc aatgataagg caggtatctt ggatattcca aaactaatag aaaaatataa
    54661 ggctggagaa tgtatctcct attttcgcaa acagaaagat tacggtggta cagagaaaaa
    54721 tgggtatgat acaccacaaa atacaggcga aaccttatat ctcggttcaa caagtagcga
    54781 attatatatg tgtgcttatc agaagaatta tgagcagtat gtcaagaatg gcacagaagt
    54841 tgaagataca gaaatcaaga accgttttga aatacgcatg aagaatgaac gagcctatta
    54901 tgcggttgta gatttactga cttatcggga cgctgaacgt actgcttttt ctatcatcaa
    54961 tcattatgtc cgttttgtag atagagagga cgataaaccg aaaagtcaat ggaaaatgaa
    55021 tgatgattgg gcgtggtttg taggagaaaa cagagagccg atacgcttaa ccacaaagcc
    55081 agagccttat actttacaaa aagcattgca ttggctacaa agacaggttg caccaaccat
    55141 aaaaatggta caggcattag acaaagaaaa tcatacaacg atactaaaag atatgattga
    55201 acaggcagaa ctcaaagaca agcataaaca tttattacag ttagaaaaat caaccataga
    55261 agaacgcata gataccgttg ttccacaaga gaatgacggt attttttaat ttctttaaaa
    55321 aatctgcaac aaaacatcaa ctagcgtaca gatatggtac gagaaaagga aatctaaact
    55381 tttttgaaaa taggtcatta aatcgaggtt tccattccct atatgaagtg aaagaagaaa
    55441 agttttgaaa aatgtcggaa aatcgagtta agcggacagt gttatgtgaa aagaagaaat
    55501 ttttttcatt ctcaacttaa caatcagcag tttccattcc ctatatggag caaagaaaat
    55561 ctttcattcc atagttggca gtaacggtgt tgcatgggta gttagggtgt gaaaagaaat
    55621 cttttcatca tcaacttagc agaatgacat tttctttccc tatatggtac agaaaaagaa
    55681 aaaagttttg agtattggtt acgcttttgc tcttttccaa cgcggtatat aggaaagacg
    55741 attttcttct ttcgtgttct ttgacaattg aataaagcaa ttcaatacat tagacagaca
    55801 gtaagccatt gaaacagata cgccatgacc tttcccctgc aaaagcgagc gacaacctat
    55861 ctgtgttctt gtaaaagact tgtcctcttt tatcgccatg acctgtcctg tctgataatg
    55921 atactcccgt acagccacag cttgagcgtt aaaagcgtcg cacgcaatgg gtacggctac
    55981 attggataat gcagaggtgg aactcctgtg ggctatgaca aaagctgttg aattgcttag
    56041 aaagatttta cagaaagggg ggtatgtgtt attgataatg ctgtaaaaac aattcaaaag
    56101 aaaaataaca agtgtggcat tggaaacaga ggaaagacaa agattgttgt aaaagagcat
    56161 ttttccgaaa agggaaagac aatggaagaa cttttaactg atgttatgct tgagaaagca
    56221 aagcagacaa tcgcataaat tcggtgcagt tgtaagaaat agattgaatg gcaaaaagta
    56281 cccgtgttat actttacttg caagcaggta ttgtaaacac gggttagtta taaaggagga
    56341 taactgacaa tgaaacaaca gatttacaat actgcacttt atcttaggtt gagccgagat
    56401 gatgaattac aaggcgaaag ttccagcatt accacacaaa gaagtatgtt gcgtctatat
    56461 gcaaaagaac atcatttgaa tgtcattgat gaatatattg atgacggctg gtcgggaaca
    56521 aattttgaaa gaccgagttt tcagagaatg attgaggata tagaggtagg aaaaatcaac
    56581 tgtgttgtaa caaaagacct ttcccgactt ggcagaaact atattatgac aggacaatat
    56641 acagaattgt attttcccag ccataatgtc cgttacatag cgattgacga cggtgtagac
    56701 agcgaaaaag gcgaaagtga gattgcacca tttaagaata ttatcaatga atgggtggca
    56761 agagatacaa gccgtaaagt gaaatcagcc tttaagacaa aatttgcaga gggtgcgtat
    56821 tatggggctt atgctccgtt aggatataag aaacaccccg acatcaaagg gaaactgttg
    56881 gttgatgagg aaacaaaatg gattgttgaa aaaatcttct ctctcgccta tcaaggttac
    56941 ggtagtgcaa aaatcacaaa aatactgcga gaagaaaaag tcccgacatc gtcttggttg
    57001 aattttacaa ggtatggtac ttttgcacat atttttgagg gcaaacccga aagtaagcgt
    57061 tatgagtgga cgattgcaca aatcaaagga attttgaaaa gtgaagttta tatcggcaac
    57121 agcgttcata atcgacagtc aacagtatca ttcaaaagca agaagaaagt gcgaaagccc
    57181 gaaagcgaat ggtttcgagt agaaaatacc cacgagccaa ttattgaaaa agaagtgttc
    57241 tatcgtgttc aggaacagat aaaatcaagg cgtagacaga caaaggaaaa ggcaacgccg
    57301 atatttgcag ggcttgttaa gtgtgcggat tgtggctggt ctatgagatt tgcaacaaat
    57361 aaggcaaata agacgcctta cagttattat gcttgcagtt tctatggaca atttggcaaa
    57421 ggctattgtt ctatgcacta tatccgctat gatgtgctgt atcaagctgt attggagcga
    57481 ttgcagtatt gggctaaggc agtacagcag gacgaagaaa aggtattgca taagatacag
    57541 aaagtcggta atgccgagcg aatacgggaa aagaagaaaa aggcaagtgc cttgaagaaa
    57601 gccgagaacc gacaaaatga gattgactgt ttatttgcga aaatgtatga agatagagcc
    57661 tgtgagaaga taacagaacg aaacttcatt atgctgtcgg gaaaatatca aaaggaacag
    57721 atagaactgg aacagcagat aaccgactta agagaagaat taagtaaaat ggaacaggat
    57781 atgataggtg ctgaaaaatg gattgagtta atcaaggagt attccgtacc aaaggaactg
    57841 acagcaccgt tattaaatgc aatgatagaa aaaatactca ttcacgaagc aacaacgaat
    57901 gaggagaacg aaagaataca ggaaatagag atatactacc gatttattgg aaaagtagac
    57961 tgataaatag ggttcatatc tttaactaag ggagacggaa gttggttacc ctgtagaaga
    58021 attttttcaa gattactttg cggagtatgc cgataggata atgagagatt acgtaacaga
    58081 taaaactcaa gaagtcatca atcaatccca gtcattaaat gaattatctg ataaggcgaa
    58141 agaagaagca gttgccatta tt
//
LOCUS       DAPBCF010000013        56349 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.013, whole genome shotgun sequence.
ACCESSION   DAPBCF010000013 DAPBCF010000000
VERSION     DAPBCF010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 56349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.013"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            290..1135
                     /locus_tag="RD508_000976"
     CDS             290..1135
                     /locus_tag="RD508_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7735588.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="RD508_000977"
     CDS             1416..2636
                     /locus_tag="RD508_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HDT7735589.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="RD508_000978"
     CDS             2633..5353
                     /locus_tag="RD508_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7735590.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="RD508_000979"
     CDS             5337..6281
                     /locus_tag="RD508_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7735591.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6350..7360)
                     /locus_tag="RD508_000980"
     CDS             complement(6350..7360)
                     /locus_tag="RD508_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7735592.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7540..7884)
                     /locus_tag="RD508_000981"
     CDS             complement(7540..7884)
                     /locus_tag="RD508_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDT7735593.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7877..8311)
                     /locus_tag="RD508_000982"
     CDS             complement(7877..8311)
                     /locus_tag="RD508_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HDT7735594.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8449..9186
                     /locus_tag="RD508_000983"
     CDS             8449..9186
                     /locus_tag="RD508_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7735595.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9179..10390
                     /locus_tag="RD508_000984"
     CDS             9179..10390
                     /locus_tag="RD508_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7735596.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10594..11376
                     /locus_tag="RD508_000985"
     CDS             10594..11376
                     /locus_tag="RD508_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HDT7735597.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11446..12108
                     /gene="trmB"
                     /locus_tag="RD508_000986"
     CDS             11446..12108
                     /gene="trmB"
                     /locus_tag="RD508_000986"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDT7735598.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12206..13960)
                     /gene="ade"
                     /locus_tag="RD508_000987"
     CDS             complement(12206..13960)
                     /gene="ade"
                     /locus_tag="RD508_000987"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDT7735599.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14092..15021
                     /gene="tadA"
                     /locus_tag="RD508_000988"
     CDS             14092..15021
                     /gene="tadA"
                     /locus_tag="RD508_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HDT7735600.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14978..16027
                     /locus_tag="RD508_000989"
     CDS             14978..16027
                     /locus_tag="RD508_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HDT7735601.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16024..16302
                     /locus_tag="RD508_000990"
     CDS             16024..16302
                     /locus_tag="RD508_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDT7735602.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16277..16747
                     /locus_tag="RD508_000991"
     CDS             16277..16747
                     /locus_tag="RD508_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDT7735603.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16764..17066
                     /locus_tag="RD508_000992"
     CDS             16764..17066
                     /locus_tag="RD508_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735604.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17083..17454
                     /locus_tag="RD508_000993"
     CDS             17083..17454
                     /locus_tag="RD508_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HDT7735605.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17426..17785
                     /locus_tag="RD508_000994"
     CDS             17426..17785
                     /locus_tag="RD508_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735606.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17957..18964
                     /locus_tag="RD508_000995"
     CDS             17957..18964
                     /locus_tag="RD508_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7735607.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            18989..20173
                     /locus_tag="RD508_000996"
     CDS             18989..20173
                     /locus_tag="RD508_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDT7735608.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20610..22193)
                     /locus_tag="RD508_000997"
     CDS             complement(20610..22193)
                     /locus_tag="RD508_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7735609.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22771..22914)
                     /locus_tag="RD508_000998"
     CDS             complement(22771..22914)
                     /locus_tag="RD508_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HDT7735610.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23137..23616)
                     /locus_tag="RD508_000999"
     CDS             complement(23137..23616)
                     /locus_tag="RD508_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7735611.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23689..23973)
                     /locus_tag="RD508_001000"
     CDS             complement(23689..23973)
                     /locus_tag="RD508_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735612.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24051..24245)
                     /gene="ssrS"
                     /locus_tag="RD508_001001"
     ncRNA           complement(24051..24245)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="RD508_001001"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24317..25603)
                     /locus_tag="RD508_001002"
     CDS             complement(24317..25603)
                     /locus_tag="RD508_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HDT7735613.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25741..26412
                     /locus_tag="RD508_001003"
     CDS             25741..26412
                     /locus_tag="RD508_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HDT7735614.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26378..26866
                     /locus_tag="RD508_001004"
     CDS             26378..26866
                     /locus_tag="RD508_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HDT7735615.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26879..27826
                     /gene="prmA"
                     /locus_tag="RD508_001005"
     CDS             26879..27826
                     /gene="prmA"
                     /locus_tag="RD508_001005"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDT7735616.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27827..28591
                     /locus_tag="RD508_001006"
     CDS             27827..28591
                     /locus_tag="RD508_001006"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDT7735617.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28824..31037
                     /locus_tag="RD508_001007"
     CDS             28824..31037
                     /locus_tag="RD508_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HDT7735618.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31048..31494
                     /locus_tag="RD508_001008"
     CDS             31048..31494
                     /locus_tag="RD508_001008"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDT7735619.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31665..32924
                     /locus_tag="RD508_001009"
     CDS             31665..32924
                     /locus_tag="RD508_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HDT7735620.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33013..33960)
                     /locus_tag="RD508_001010"
     CDS             complement(33013..33960)
                     /locus_tag="RD508_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7735621.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34354..35646
                     /locus_tag="RD508_001011"
     CDS             34354..35646
                     /locus_tag="RD508_001011"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDT7735622.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35661..37430
                     /gene="aspS"
                     /locus_tag="RD508_001012"
     CDS             35661..37430
                     /gene="aspS"
                     /locus_tag="RD508_001012"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDT7735623.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTRAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37539..38414
                     /locus_tag="RD508_001013"
     CDS             37539..38414
                     /locus_tag="RD508_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7735624.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38680..40563
                     /locus_tag="RD508_001014"
     CDS             38680..40563
                     /locus_tag="RD508_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDT7735625.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40638..40922)
                     /locus_tag="RD508_001015"
     CDS             complement(40638..40922)
                     /locus_tag="RD508_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDT7735626.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40912..41646)
                     /locus_tag="RD508_001016"
     CDS             complement(40912..41646)
                     /locus_tag="RD508_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HDT7735627.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41775..42398
                     /locus_tag="RD508_001017"
     CDS             41775..42398
                     /locus_tag="RD508_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDT7735628.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42590..43711
                     /locus_tag="RD508_001018"
     CDS             42590..43711
                     /locus_tag="RD508_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDT7735629.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43718..46846
                     /locus_tag="RD508_001019"
     CDS             43718..46846
                     /locus_tag="RD508_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HDT7735630.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46865..50059
                     /locus_tag="RD508_001020"
     CDS             46865..50059
                     /locus_tag="RD508_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HDT7735631.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50205..50912)
                     /locus_tag="RD508_001021"
     CDS             complement(50205..50912)
                     /locus_tag="RD508_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDT7735632.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51677..52075
                     /gene="spxA"
                     /locus_tag="RD508_001022"
     CDS             51677..52075
                     /gene="spxA"
                     /locus_tag="RD508_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HDT7735633.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52407..53060
                     /locus_tag="RD508_001023"
     CDS             52407..53060
                     /locus_tag="RD508_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HDT7735634.1"
                     /translation="MEMEHINENTIRVLIGHKDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53286..54284
                     /locus_tag="RD508_001024"
     CDS             53286..54284
                     /locus_tag="RD508_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HDT7735635.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54460..56268
                     /gene="pepF"
                     /locus_tag="RD508_001025"
     CDS             54460..56268
                     /gene="pepF"
                     /locus_tag="RD508_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDT7735636.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18539 a         9724 c        11679 g        16407 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 tcgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aaaaagcgag acataagtct tcgctttttt tgttttcttt tattttgatg
     6361 aatcagttgt ttcttcagtt gaagattctt ttgttgaatc agttgatttt gtgtcagaac
     6421 tctttgttga agctgtagtt tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg
     6481 cactcaacac attttcaaag gcatcatctt tgatttttac atttgcatct tttaattctt
     6541 caccgattac tttagttgtg aatgcattgt cacttagttt agtttcagta gcgatatctt
     6601 ttagttgatc tttgtattta tccatgtcat tgcctttatt ttggtttttc accattttga
     6661 caacgtagta ttctgtcgca taagaagtag gatttgttgt agtaataaca tcggagatct
     6721 caccgtcttt caatttgaaa gctgcttctt ttacttctgc aggaatagtt gttgtcgttg
     6781 agtcgaattt aactttaccg ccatcttctt ttgtctctgt atcagttgat ttgtctttgg
     6841 ctaatttaga gaaatcatct ccatcatccg ctgatttttt cacatctttt gcttcatctt
     6901 cacttgataa tttgatgatt tgtgcttcta cttctggatg gaaagatttc caagcagttt
     6961 tcaaatcgtc atctgtaata tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt
     7021 tacgaatata ttctttataa gtatctttcg tatatccagc agcttctaat tgtgattcaa
     7081 aagtatcacc taatgatttc gcttgtttgt cgtattctgc atccacttgc ttatcggtta
     7141 ctttatcgcc atatttgtta ttgaatactt tataaatgat catccgttgt actaaggatt
     7201 ggttcgatga ttcaagtttt gcttcatcat agaaatcaga tacagtgatc gttccgcctt
     7261 tcatcgttgc gatatcttta ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca
     7321 acgcactagt agctgccaaa ataattgatt tttttttcat taaaatttgc actcctgtaa
     7381 ttagttatta tttttatata ttaactatac catatcccat ttcctttaaa aacgttgtcg
     7441 tggtagtttc aaacaaaatt caaaatttca tcacattcct aggaaatacg caaacttttc
     7501 tcacttatat agttaaatct gttgagaaaa taatcattat tatatttgtt caggatactc
     7561 tggcagatca gcttttagtt tttctacttg ttcattgatt tgtgtgatac gtggttcggc
     7621 ttggaattta aaatcttcga tatctttttt gattgcttct tggaaagcag gaatcacaga
     7681 ttcagctgtt tcttttgttt cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa
     7741 atcatttgtc agagttgttg cttcttccaa ttcttcgatc agtttctttc ttgtttcatt
     7801 cccgctcctg ggcgccaata acagacctcc gacagtgcca gcagcagctc caaataacag
     7861 tcctttgaaa aagtttttaa tcatcgcagg acacctgctt tacgattgtt tcttgaatag
     7921 cttttagttc ttccgatcca taactatctt gatgattgac aaagtgaata gaaaaatcat
     7981 cctctttgct gtagcgaggg actaaatgga tatgtgaatg aaaaacagat tgataggcta
     8041 gttcacggtt gttattcaag atattaagac ctttcatttc tggaaaagct ttttccaatg
     8101 cttgagcaat cttaggcaca cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa
     8161 aaatatctgc tacatgacgt ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga
     8221 tgtctaaaaa agcatagacc ttgtcgtctt catatatttt atagcttggg atttcttgat
     8281 tgatgatttt gcaaaaaata cagttttcca tataaaacat cctttctata aagaataaat
     8341 acttcagctt aactttacca taagttaaag ctattgtaag gaaaaaaaca aaataccgtc
     8401 attttcttcg tggtataata aataaaaata aatggcggag gaaaaagaat gagtttaatt
     8461 atcgatcatg tcacaggggg gtacggacat ctccctgtgt taaaagatat cagtttcgat
     8521 gtacagcctg gagagatagt agggttgatt ggactgaacg gagcagggaa aagtacgacc
     8581 atcaagcaca ttatcggtct gctggaagct tcaaaaggaa cgatagaaat caatcatcta
     8641 tccttaaaga aaaatacgga agaatatcgc aaacaaattg ggtatattcc agagactcct
     8701 tctttatatg aagaattgac attgagagaa catatcgaag tcactgcgat ggcctacgat
     8761 atacctatgg atatagcaat gaaaagagca gaaaagttgt tggagacttt tcggttatct
     8821 aatcgtcttg actggttccc agctaatttt tcaaagggaa tgaaacagaa agtgatgatc
     8881 ttatgcgcct ttttgatcga gccttcttta tatatcatcg acgaaccatt tttaggcttg
     8941 gatccactag ctatcaatgc attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc
     9001 ggtattttga tgtctacgca tattttagct actgcagaaa aatattgtga tcgttttgtg
     9061 gtcttacata acggagagat acgagcagac ggttctcttg agatgttgag aaaagaattt
     9121 cagctgccgg attcttcttt ggacgaaatc tatattgctt taacaaagga gcaggcacat
     9181 gagtagtttt tttcaaaaac gtttagcaag acatcaaaag aaaatgatga aatatatgcg
     9241 ttatgtattg aacgatcatt ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt
     9301 atattattct aattggttga aaaccctgca gccaccgttt gcaattggag ggctcataat
     9361 ctctgtattt tggatgctct gtttattcgt gggtaagatg gctacttttg cagaggcagc
     9421 agatattgtt tttttacttc ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt
     9481 tcgctattct tgcatttttc cgttgatctt tttgatattg gcatgcggat tggccatgcc
     9541 attagtggtg gttagtacgg agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt
     9601 atggagtttg aaattcagtc atctgcaaat caagagagca gaattgtttc gactagatca
     9661 acaagttatt cgttattgga aattaggctg gtttttttct tctctgatct ttttgtttct
     9721 atcattttat tggctaatat gggcaggaat agcaggtgca ttagtacagg caagtctata
     9781 ttactggttt ttgtggaagc aacaagaaaa aggattggat tgggagaaaa tggtgcatgt
     9841 agaagaacat aggttgcatc agatctatca atttatcaat ttattcacag atgttcctga
     9901 aattacggca aagatcaaaa gaagacgcta tttggatcct atattgactc atattaaaag
     9961 agaatcaaaa aacacttatc tttacttgtt tgcaagaaga ttggcaagag gttctgattt
    10021 tagtggtctt tatttccgat tagtaattat aggtgggtta ttgattgccg gagtagtcga
    10081 cttttatttt agtctgatta tcggtttctt atttttatat ttgatcggtt tccaactgtt
    10141 acctttagcg aaccagttcc gctatatggt tctcgttcag ctttatccaa tccataagaa
    10201 tcagaagaag caggcgattc agtatctact cacatgggta ttaattatcg cgtcggttat
    10261 ttttggtttg attgctgcag tcgtattaga tgggcagcag cgatgggttc cgctagcggc
    10321 ttatttgatt gttactatgc tctttgttaa actatatgta ccaactcgtt tgaagaagat
    10381 gtcagactga aaacaaagct gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca
    10441 gtaagaatgc tgttcgttct attttttttg agaaaagctg gttttttgaa tggcaattaa
    10501 atgaaaaaga acgtatatgt gcttgacgtg tagtgttcag gcgactagaa taataagtac
    10561 tgcaaaacaa agagtaagag gacgggagaa tgcatgatgg agtttcagtt agaccaagag
    10621 tggcggttac gtcccatcaa aggcgacaca ggaaaaacat acataggcat gcgtgatgag
    10681 gacaaagtct ttattaaacg aaacacgact ccgatgttgg ctgctctttc aagggaagga
    10741 attacaccaa aacttgtttg gacaaaacga acggggaatg gcgatacttt gacagcacaa
    10801 gagtggctgg aaggtcgctt gctgactcct aatgagattg gtcaaagaaa cgacgtgatt
    10861 gatgttttgt accatttaca tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt
    10921 ggtcgtgtca tgacgccgga gaagatgctg caaaaatatg aaaaagaatt accggaagaa
    10981 ctccagaaaa atcaatttct gcaaattgtc catcgttttc ttcgtgagca gatcccgtca
    11041 atagataagg aaaacttatc agtagtacac ggagatgtaa accatcgtaa ttggttagta
    11101 tgtaaaaatt atttatatct agtcgattgg gattcaatca tgtttgcaga ccctgcggtg
    11161 gatattgcaa cgattttagg aaattatgtg ccactgtcta gctggaatca gtggctgatc
    11221 agttatggca tacgcccgac tgacgaaatg cttgaaaaat ttcattggta tgcggccatg
    11281 aatttgctcc aagaaatcac cagatattgc aaacgtgaag atcatcgacg gatgaacgaa
    11341 gaaattttac aattaaaacg aattttcagt ggctgaggtt tggcccaaac tctgcggaga
    11401 tttggccaga cctttttaat tagaggaaag gaatggagat aaataatgcg tgtccgaaat
    11461 cgtccgggag cagcggaaat gttagcggct cacccgaatt ttgtaattag tgatccaaca
    11521 ttgtggaagg gaaaatggaa tgaattgttt gaaaacgatc atccaatcca cattgagatt
    11581 ggtatgggga aaggccagtt catcactgga atggcaaaag cccatcctga aatcaattat
    11641 attggagtag aaatgcaggt cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa
    11701 ccgcttccta acctgaaact tctacatgtg gatggatcag cgttgacaga gtatttcgct
    11761 gacagcgaag tagatcaaat ctatctgaat ttttccgatc catggccaaa aaaacgtcat
    11821 gaaaaacggc gattgacata taagactttt cttgctgtag atgaacagat tcttcgtcca
    11881 aatggagaaa tccatttcaa aacagataat caaggattgt ttgagtattc tctggcaagt
    11941 ttttctcaat atggcatgat cctcaaacag gtatggttag atttacatca aagtcaattt
    12001 gaaggcaata ttatgacgga gtatgaagaa aaattttctt caaaaggtca acgtatttat
    12061 cgagtagaag ctcaatttca agataagacc aaaaagaaaa gtctgtgaaa ctaactttct
    12121 gctttcataa aaacattaat atccataaat aaatcccaga aaatgaacat tacagatgta
    12181 atgtattttc tgggatttat ttgatttaaa atgtatttat ttcatcggtt tttccacaag
    12241 gtggaatcaa ttggaagcga gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg
    12301 gtatgacaga taatgttaag aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc
    12361 ctagttgatg tgctttagtt attaattcat tcaactgttc atagacgatc gaaaaaggtt
    12421 cctgtgtcat gattccgcct ataggaagag aaacacaagc tatttcctgc tgtttgttga
    12481 caacggtcat cccgccacct ttttgaatca aaagattagc agcatacagc atatcctcgt
    12541 cgtttgtccc aacgacaact agattatgcg agtcatgggc aatcgttgtc gctatcgctc
    12601 cttgtttcag ctgaaatcct ttcactatgc ctaatccaat gtttcccgtt tgatggtgac
    12661 gctcgatcac cgcaatcttt aattggtctt tttcgattga aggaatgaat cgttcgcctt
    12721 gtcggtccac tttttctacc aaatctttag tcactagact attcgggata atttcgatca
    12781 catgggcttg tgaagaagaa agaagcagct ctaacgaatg tggatttaat ggttgagcgt
    12841 ttagttttgg cagacaacac gtatatgaat ttgaatgatc agcaaataaa tggtcttgga
    12901 gttgcccaga ttgaacaact aatgttccct tatagaaaac ttcatgaatt ggcagcttgg
    12961 taagatcgtc tgttaagaag aaatcagctt gatacccagg ggcaatcgca cctagtgttt
    13021 tcaaatcaaa acattctgct gcattcaatg ttgccatctg aatggcttgt aatggatcga
    13081 ttccaagtgc aatagcttga cggacgatat gatcgattga tccttctttt actaaatcat
    13141 tgatcagttt atcatcggtg acaaagaagc atcttcttga attttcaggt gtgatcgccg
    13201 gtagtagcga tgccagatct tttgcaacgg tcccttctcg aaccattaaa tacataccaa
    13261 gatccaaacg ttctttagct tcttttgcag ttgtagcttc atgatccgtc cgaatacctg
    13321 ctgcaggata aacatttaac tcttccatgc cgataccagc tgcatgcccg tcaatttttt
    13381 tcttatgctg gtgcatcaat tggatctttt ctaggatgtc tgtttcatta tttgctactg
    13441 cttgatagtt catgacttca gctaagccta aaacttcggg tttttgtaaa aaaggggcta
    13501 atttttttgc atttaaattt gcaccattgg tctcaaaagg ggttacaggt acacaagaag
    13561 gtagcataaa aaagatattc atgagtgttt gtcttgcatc ttctatcata aactcaagac
    13621 ctgtactccc agcaatgttt cctatttcat ggggatctgt cactacagta gtaactccat
    13681 gaagcaagga tacttttgaa aattcgcttg gtgataaaag tgagctttcg atatgcacat
    13741 ggccatcgat gaatcctggc actagatatt gcccattagc attatgtacg ctttttcctt
    13801 cgtattcacc gattcctacg atcattcctt cgcagattgc tacatctttt tccatgattt
    13861 ctttcgtaaa gacgttgacg atcttagcat gcttgatcac taggtcagca ggcttttttt
    13921 tacttgctac ttcgatatat ttccttaatg ttgtttccaa tggagtgcct cccaagataa
    13981 atttttataa gtataacata aattcggttt ttgccaatat ttttttgtaa attcatttta
    14041 tttgaaacaa aaagatcaaa aagacgtatg ttttttgtgg aggggagaat aatggaaata
    14101 aaacgattat cggatcaaat gataagtgaa agttttgcca aacatgccca agacgtatat
    14161 atattgccag cttcagaagt attttacatc tattttcgct atggaaaaaa acgaacattc
    14221 tggaagaaag tctcttcggc agatggacag caactgatct caagatttaa gtatttggga
    14281 cagatggata tcggagaaaa aagaaaagct cagttaggtg catttactta ttctttagaa
    14341 aaacaggaag ttcgtctgcg gttgtcttct gtaggagatt accttcaacg agagagttta
    14401 gtgattcggc tattatacgg tacttttgaa acaccccatc gttgctttag ttctcgagat
    14461 tttgcaacta ttttacagaa aaccgtcaga cgtggattat accttttcag cggaccagtc
    14521 ggatcaggca agacttctct aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt
    14581 actatcgaag atcctgtaga gatagaagaa ccgttttttc tgcagctaca gatcaatccg
    14641 aaaatagcac agacttatga tacacttttg agactcgcat tacggcatcg tccagacttg
    14701 ctaatcattg gcgagataag agatgaatca actgcacatg ctgcggtaag agcagcacta
    14761 acagggcacc gggtttttgc aaccgtacat gcacgcaatc ttgaaggtac attggtcaga
    14821 atccatgaac tgacaaagaa aaaagaagag ctatctgaat gtttagctgg tgtcatttat
    14881 caagaacttt tggaagatgc caatcaccat ccttctgttt tatggagtta tcaatttatg
    14941 gaggaagaat cagtaaaaaa atcatgggag gaaagttatg aagaagctca ggaaaatatt
    15001 tggcagtcag aactattcta aaggattaac aagaagccag caaaaccagt ttgcacaaac
    15061 catgggagaa ctgcttttat ctggttttag tctgcaagaa tccctttatt tattactcac
    15121 gatccgttcg tttccacctg ttattttggc aaatatccaa catcagctaa aggaagggca
    15181 agcgtttagt gaggtacttt cgcaaatagg atatggagca gagcaactgg tacagatcga
    15241 gttagctgaa cgtcatggga atctgccgac aactttgttg gaaattgcca aacagtttcg
    15301 gcttgttgaa ggatttcgca atgatttgaa aaagctgctt gcatatccga tgctattgct
    15361 cacctttttg ctaggtatct tgtttagtat gcggttgttc gttttgcctc agcttattgg
    15421 ttcaggaatg gtcatgcaag agcattgggg tattcagctg atacaagtct ttcattggta
    15481 tgttctacta ttcatcctag cggttactct attggcttta ctagtaaggt atcgtctgat
    15541 gaagttgtct cctgttgatc agagtgaatg gataagcaga caattattga ttggaccgat
    15601 atattccttg tatcaatcgg cttatttgtc actagagatt ggaaagcttt ttcatgaagg
    15661 tttcgaatta aggcaaatca tagtctgctt aaaggaaacg aaacaagaaa gtctgattca
    15721 gcatcttgcc tctaagttga ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt
    15781 ccagaattat cgttttctat cagaagaatt cagtaaaatt gttttacagg gagaggcaaa
    15841 gggaagttta ggtaaagaac tgatttttta cagcgaatgg acaagaaaac agcttttcaa
    15901 acgtcttcat cactggatgc attttattca gccaatcatt tttttgggcg tagcggcttt
    15961 gattttatta gtttatgccg ctgttttatt acctgtttac ggaagcatag aggaggtttt
    16021 gccatgaaaa agagaaaaat atcttattat agcggtttta cattgatcga aatgctaatc
    16081 gtcttactga tcatcagtgt attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg
    16141 aatcatgtag accaagaaag tcgtgaagcg atcatccagt tggtagacac acaaaaagag
    16201 ctctatgcgc ttcaaaataa tggaagagtt cctactgtgg aggaattgtt gaatgaaggc
    16261 tatatcaaac gagaacatgc agaaatctat cagcggcctt gaaggtaagg ttttagcatc
    16321 aggatatacg ttgtttgaat cactcttact gattttatta cttacaacga tcctttcttt
    16381 tccagttctc gcattttctg catggaagaa tgaattggca gtctatcaat ttttcggcca
    16441 atttgaaaaa cgaatctatt ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg
    16501 cttttattgg aatagtgaag agaatcaaat catttttcat gttccgaatc cagataaaat
    16561 aaattgggaa gtattagata ttcctgatga gattaccttg aaacgccatg cttctattac
    16621 ttttgctgct agaaccggga atgaaagttc actaaaagct tatcaatttt attgggaaga
    16681 aaaagagcgg acgattacgt atcaattcca gatagggagt ggtcgctata caaaaagaat
    16741 tgaataaaac aggatttgtt ttgttggagt cccttacagc gcttatgatc gcttctgtct
    16801 gtgtctactt agtgagcttt ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg
    16861 aggaactgct atttattcga atgatttatg aagatatcaa gacgcagcgg atgtatcaca
    16921 aaagaccaga gcgaagggaa gaaatgatcc catacgatat ccaaattgtc gataataatg
    16981 gagtaatcga aaaagtgttt gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa
    17041 gtaattccag catttacgct gattgaatgt ctaattggac tgatgatatt gagcagtcta
    17101 ttgctcacat tcaatctttt gattcagcaa accatccaag taagtgaatt tttgcagcgt
    17161 aaagatcaaa aagagtggct aatattttta gcacaattag aagaagaact caagagcagt
    17221 cacaatgtct ctgtgaaaaa tcagcaactg cactacacga tcgaggataa acagtatatc
    17281 atcgaaagat atcaggcaat gatacgtaaa agaagaactt ccggcggaca tcaacctatg
    17341 ttaacaagta tcactgagct tcaattattg gaaaaagaac acacaatttc tttttatgta
    17401 cactttgaaa atggagaaga tggatatgcc atatggacaa aaaacgatca gtagaaaatg
    17461 ttataagggc tctattttat tttctgtctt gcttttattt cttttatgta cgtttttatt
    17521 gatggcagca ttagaaagct accgtttgtc aatggatctt aatatacgaa tcaaaaatta
    17581 ttatatagca aaaataatga agcagatggc tttatcggaa cagtctacgc ttgccgaaag
    17641 ttcggaagga gttttttact acacaactgg atctgtaaca tatcagtggg tacaacagtc
    17701 cctattctta gaggtggaag tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa
    17761 tgatacagat actagtacag aatgatggaa tgttcgtgaa aacgccctct tttctgttat
    17821 aacactgttt ttaataaaaa aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat
    17881 tgaaattttg tcaattgttc gatagaatta aacaggtgaa aaaattgtta taatatatct
    17941 agaaatgagg tgcaccatgt taccagaaaa aatggaacaa gggtttaatc aaaacctgga
    18001 agctattcag cttttacaga atgcattggg aacttccttt ttagaagcct atgtcgaaaa
    18061 tgcagaaaat ttaatagatg attatcaagt acgtgtggtg gatggagtgc cgacaaaaga
    18121 gacaacgcaa cggatcacag ctctttatga agagttgaag aaactttctt tcgagccaga
    18181 agaatggcgc agactgtctc aattactttt attgaagggc agccagacag aacatttgca
    18241 ggcgaaccat caactcactc ctgatagtat cggtttttta tttgtttttc ttattgaaca
    18301 actatacaca aataaaaaag caccggttaa gattctggat attgcggcag gaatgggcaa
    18361 cttgttatta acagttcttt taaacctatc gaatgcgggg taccaaacag aaggaattgg
    18421 tgtggatatt gatgatacat tgttggctgt cgcagcttct acaagtgatt tgacacaagc
    18481 aaatgttcaa tactttcatc aagacgggtt gcaggaatta ttaatagatc ctgtcgattt
    18541 tgcaatcagc gatttgccaa tcggttatta tccgaatgac gaaaaagcaa aagagttttt
    18601 aacaagtacc gaagaaggcc atagttatgc acatcattta ttgctagagc aatcaatgaa
    18661 atatgtgaag ccggatggtt ttggtttgtt tttgatgccg agtggatttt tagaaacgga
    18721 tcaaagtgaa gaaatcaaaa aatggtttaa agaagaaggt tatcttcaag gaatgattca
    18781 attgccagat gaattgttcc gtaataaaca atcgcaaaaa agtattttga tcttacagaa
    18841 aaaaggacca caagcacaac aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa
    18901 agaaccagag aaggtgacgg aatttttcaa cgagtttaaa aactggaaat catctgctct
    18961 gtaatcattc aacgagaagg agagtcatat gtctaaaaca attgcaatca atgctgggag
    19021 ttcaagtttg aaatggcaat tatatcaaat gccagaagaa accgtagttg cgaaagggat
    19081 cgtcgaacgt atcggtttac aagattctat ttttaccatc aagtacggcg ataatcaaaa
    19141 attcgaacaa atcatggata tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca
    19201 gttgattgaa ctgcaaattt taagctctta tgatgaaatc accggagtag ggcaccgtgt
    19261 tgttcacgga ggagaaactt atggggattc agtagtgatc gatgagaaag taatggaccg
    19321 cattgctgaa ttagcagaat ttgctccttt gcataatcct gcaaacttaa tggggatcaa
    19381 agcgtttaaa aagattttac ctgacatttt gagtgtggct gtattcgata catctttcca
    19441 ctcaacaatg ccaaagcaaa attatttata tagcttaccg gtgtcttatt atgaagattt
    19501 caaagtaaga aaatatggct tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc
    19561 aaaattattg aacaaaccga tcgaagaact aaaaatcatc acttgccact taggaaatgg
    19621 tgtatcgatc acagcagtcg atggaggtaa atccatggat acttctatgg gattcacacc
    19681 attagctggg gtgacaatgg gtacacgttc aggtgatatc gatccagctg ttctcccata
    19741 tttaatggaa aaattagaga ttgatattga tgaaatgatc aatgttttga acaagaaatc
    19801 tggtctgcta ggcctaacag gattgtctag tgatatgcgt gatcttgaaa agaactatga
    19861 aaaagaacat attcgtttag cttatgacat tttcgtggac cgcatccgaa aatacatcgg
    19921 cggttatgtg acaacgatga atggtgttga tgcaattgtc tttactgctg gtatcggcga
    19981 gaatgacgga catgtacgta gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat
    20041 cgatccagcg ttgaatgaat tgcgtggtga agaagtagat atctctacaa aagaatcaaa
    20101 agtaagagta ttagtgatcc caacagatga ggaactaatg attgcccgtg atgtggagcg
    20161 tctgcgcggc taagccaaag cattcgttag gataaaagat gaaacgcatg caagagggaa
    20221 ttcttgcatg tgtttttttt gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc
    20281 cttctttttt acaggatctt cttagggaat tttgcttgga aaagtggtca aaagggaaaa
    20341 gactggcatt ttatttattg attttcagga aaatcccaat attttatttt cattcatctt
    20401 tataagggac attacatatg taaaaagaaa aaacattttt agatcagcct cgtgggctgt
    20461 cgactttatt cttcgcttta tgtttagcta gaaaaccgat ccgaaacatt cattgatcga
    20521 ataataaaaa cttgattttc cacctgtact ttgcctgaat cgtgaaagca caggtatgaa
    20581 aatcaagttt tttgttgcga aaaaacgtcc tagtcaatca gttggccgag cggctggcgg
    20641 ctgatctgct cctgatcaat aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg
    20701 tcatggctga ctgctaggag cgttccttga tagtcttgca gcatttcttc aatttcttct
    20761 cgagcatagc tgtcgaggtg attggttggt tcatccaaaa tcaggacgtt gattttttct
    20821 aaaaagagtt tcagcaacgc caaacggatt ttttcaccac cggataaatc tttgatccgt
    20881 ttacccacat cgctttgata aaagccactt ttggctaatt gccgtcgagc gacttcttcg
    20941 tttccagtca atgtgatggc gtaagccagc aaacggctat cgggatcggc aaactgcagc
    21001 tgctgcggca aataaccgat ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc
    21061 ttttcctcac cgagtaataa tttgagtaag gttgattttc ctgcaccatt gtcgccgatg
    21121 atggctaaat gatctccacg atagactgca aaactgctgt ctttgaatag tacttgatca
    21181 gcgtactgct ggtgcaagtt ttgaatgatg aaaacttctt tgccagattt tccaccatta
    21241 gacaagcttt gcagccgatt tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc
    21301 aggcggcgtt ccagttcttt ggcttttttg aagaaggact cattgtctcc ttcatgtgcc
    21361 cactgacgaa aacgacgaat catgactttc aaccgctgga cttctttttg ctgcagttcg
    21421 taattttttg tcagctcagc caagcgagct tctttcaaga ctcgaaaacg gctgtagttt
    21481 ccgggatact caatcaatgc accttcttcc agttcccatg tttttgtggt gacttgatcg
    21541 agaaattgcc gatcatgaga aacgaccaga accgattttt ttgtattctg taaatagttt
    21601 tccaaccagc gaatactgtt aagatctaaa tgattggtcg gttcatcgag taaaagtaaa
    21661 tcggcatcgg ctgctaaaat tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt
    21721 tctgttaacc gtgcttcctg acggtgtgga atccctaagc cttgcaagat cgctgcaatc
    21781 cggtcttcta atacgtaacc gcctagttct tcaaagcgat gctgcagctc accgtaacgg
    21841 gccagacact tctctaagtt tgtatctggt tctgtcatca atgcttcgta gcgactcatt
    21901 tgctgtttga ggtcctgtat ctcagcggca gaatggagca agtagtggtt gacggtcgct
    21961 tcggaaactg taagttcttg ttcgaccgtc ccgatcttta agcctttttt gcgactgata
    22021 acaccgctgt cgacaccttc tctgccggtc aagatttgta aaaaggttga tttgccagtt
    22081 ccgttgatac cgactaaggc aattttttca ccagcttcaa tttgacagga taaatcctca
    22141 aataatggat tcccgccgat tgttttttta atagaaattg cttgtatgat catgatctct
    22201 ctccttgaga ccactcaaaa aggccatggt tatccatggc ctgtgttatt taaactcaga
    22261 ttatcatgag aaaaatacct tgagatggcc attgatttta cgtgaattca actgttttgg
    22321 acaaacttgt cccgtcaaca gcaactgtaa aaccaattgc atggctaaat gcgatatggt
    22381 atcgttggta attttcatta cttgttattt tagtcatgcg catcatagta ttttccctcc
    22441 ttcgtgtagt tgtcttttcc agtgtacctg aaagtgtcag aaagttcaac tagcgctgac
    22501 atttacttaa tatttatcga tgtgtaattc tgtcagagag ctttttttat ctgactgagg
    22561 gtaatgtctc gtggaccaca tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca
    22621 tatggtgttt gataaaaaac tttgtctaca tgacttcctt ttgccatttg cttaataccg
    22681 ttgcattaaa cagctcttct ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt
    22741 gtggttgcaa tggcaagcgg tagcctttca tcaattcttg aatgatttac cgaatgtagc
    22801 acttgccttc tcgcggtacc cgaacccgaa ataaaatttt agtttggcga taaaatcggt
    22861 atccgccatc gatacttcat attttttcgt atcagattca tcggaaactt ccacattgac
    22921 gaaccaataa gctttggcat gcttaggtcg ttttaaacca caccagggcg actaatcgcc
    22981 ctggtgttca ctttttttta ttttacttga actcattgac tgttttccct ttattttaaa
    23041 cattataaag accgatgagt gcttgccgcg tcttttgttt ttatcacggt tttttgtgca
    23101 aaaaaacctg ccgatagttg gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc
    23161 tggcaattgg ttttctaaat cagttcggac aacaagcaca tcgcaagctg cgtttctaat
    23221 aacatattca gaaacagaac caataaataa acgttctaca gcattcaatc ctgtggctcc
    23281 taacataatc aaatctactt gattatcttc tgggatttct ctggcaataa tttgttttgg
    23341 tgagccatat tctacgacag aggttacatt attcaagcca gctttcttcg cattgctttc
    23401 ataatctgcc aatgtttgct ttgccatttc agtagcttgt tctgcaagca ttccatcaaa
    23461 ggatgaaacg gtttggaaag aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt
    23521 atttcggata gctacattga ccgccttttt aaaagctaat tcagcttcat cagaaccatc
    23581 tacggcaacc atgatttttt tgtattgttg taacataagc attcactcct caagtcaatc
    23641 gtattgtact cttttattgt agaacacttt agggaaaaag agaattattt actgctttgg
    23701 ttcagcaatt ttttttgcaa atcggatact gaaggtggca gaaacaataa ttacgatcag
    23761 taaaaagacc aaggcaataa agcgttgatt gaaaaaagct gttaaaatac ccattacgcc
    23821 taaaacagca tatgcagctc cgtaaaattg taggaatcct tgatttttat catttttgtt
    23881 gatcaataca aaaaagatat cctgtttatt aaataaataa tagctaacga ataataatac
    23941 taaagtggcg ataatcatta aaatcctaat catgaacaaa tcctccaaaa taagcaacaa
    24001 atagaaaaag caatttgcca agagcaaatt gctttattct ttaaaagatg gtaatctccg
    24061 ttaatgccgt tgtttgtcct gtagtattga tcccgcgaat tcaagcaggt gggtcccatg
    24121 gtcgtagctt cgaactacca aatgataagg catgttacca gcagtgacac aagacgggtc
    24181 ccaagatatc aataaaaatg ttcggtcaac acacaaagag gacaattcga acatcacaga
    24241 tttcccacct ctatagtagc atatgaattt aaaaagagca atgagagagc tcgcagaaac
    24301 agaaccgttt tcttgtctag ttttttggag gatgcttttt ccactctttt atacggtaat
    24361 actgttgacc cagagcctgt tcatatttcc ctgtatcttt tggctgataa tactgagcat
    24421 tcttcagttt atctggtaaa tattgctgat tgacccaagc ctgatcaaaa tgatgaggat
    24481 actgataacc cacgccacgg ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat
    24541 gatcaggaac atctccagct ttgccctctc gaatatcagc aagtgctgca tctaatgcca
    24601 tgtaggcaga attggatttt ggcgacaagc aaagatcgac gacgacgtct gctagtggga
    24661 tacgtgcctc aggcaatccc aatttttcag cagctaatac agcgttcact gtacgagccg
    24721 cagcagcagg attacctaaa cctatatctt cataaccgat aaccatcaga cgccggcaaa
    24781 tacttgccag atcacctgcc tcaactaaac gggcgagata atgaagtgca gcatccacat
    24841 cacttccacg aatcgatttt tgaaaagccg aaataacgtc ataatgagca tctccatttt
    24901 tgtcatgggt aagagctttt ctttggacac attcttcaat gatcgacagt gtaagatgaa
    24961 tccttccttc tttatctgaa ggagtcgata gtgtagccag ttccagccca ttcaatgcac
    25021 tccgcaaatc gccgttcgtt gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga
    25081 ttgcttgttg tccaaggccg cgttctttat cccttaaagc atgttcgact gccaactgga
    25141 tgtcttgttc tgttaatggt ttgacttcaa agatctgtgt acggctgcgg atcgctggat
    25201 tgatggtaat ataaggattc tcagtagtcg ctccgatcaa gatgattcgg ccactttcta
    25261 aatgaggaag cagaaaatcc tgttttgttt tatctaatcg gtgtacttca tccaataaga
    25321 ggatcactgt accactcatt tttgcttctt ccgctacaac ttgtagatcc ttttttgaat
    25381 ctgtagcggc gtttagcatg cgaaatgcat aattagtaga gccggcgatc gcacttgcga
    25441 tactcgtttt tccagtacca ggaggtccat atagaatcat ggaagagagc atgcgagcat
    25501 cgaccatgcg gcgtatgatt tttccttccc cgactagatg ctgctgacca acgacttcat
    25561 cgatcgttcg aggtctcatg cgataagcca atggctgttg cataggattt tcctccttct
    25621 tgtttttacg tcccttaatt atatcatatt tagcaagatg cctagaaaga acagccttct
    25681 gttgttttgt tttcatagct tatccaacta atattgtgta tgataaagta ggtgagaaaa
    25741 atgacggata aacaaaagat agatgaattt ttttggaata aaacgacgcc agaagtggca
    25801 cgggatttat tggggatgta tttggagcat gacacaccag aaggaagatt agctggatat
    25861 attgtagacg cggaagcata cctaggtcca gaagacgagg ccgcccatag ctatggttta
    25921 agaagaacac cgcgtgtgcg ggcaatgtat gaaaaaccag gtacgatcta cctttacacg
    25981 atgcatactc atcggatttt gaacatcatt actcagccag aagggattcc tcaaggagta
    26041 atgatacgtg caatcgaacc cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga
    26101 aaaactggtc cagatatcag caacggtccg ggaaaattag tggaagcatt agcaattcct
    26161 caagaacttt atggtcagtc tatagcagat agttcgttac gcttagtttt tgagaaaaaa
    26221 aagacaccaa aaaagatcaa tgctttgcct agaatcggta tcccaaacaa aggtgtatgg
    26281 acagaaaagc cgttgcgttt tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa
    26341 aaccaaatcg agaaagattg gggttggagg aaagaaaatg aaaaagaagg atctattaac
    26401 atatttagat gaaataattg aaaaacaagt gacagactat gatgtagctt tagattggga
    26461 tacaaaaaat catacgatcg agatcgttgt tcgcttgttt gcagaaaata aagcacaatt
    26521 tgagattgat gatgcagaag ggatcgtttc gcaagaacca attatcgaat ttgaagacgg
    26581 cgtacttctt tttaatcctc agaaatctgt ttttgatgaa cgcaattatc tagcagtaat
    26641 cccttatgaa ggaaaaaaag ggttggcaaa atcagtagct gattctttag tggaatatct
    26701 aaatgaagta ttagctcaag ggcaaagcga tttgcttgat tttttggatg aagacgatga
    26761 cgaagctgta ttcgagcttc actgggataa tcagcaacta gcagaattag tagaagtaaa
    26821 acagcaaaat gaagcagata cttatttacc gtacccaagt tattaaggag tgacagatat
    26881 gaaatggaat gaagtaaaag tagaaactga aagtgaagca gtcgaagcag ttgctaatat
    26941 tttgatggag gcaggggcga gtggtgtcgc gattgaagat tctttagatg ttgaacattt
    27001 tcagtcggat caatatggtg agattttaga taaaaatgat tttacatcgc tgaaagaagg
    27061 cgcactagtc atggcttatt ttccggaaac gactttctta ccggaaatct tgccttttat
    27121 caaagatcgt atcacacaat tacctgagtt tggtctagct attggaaaaa ataaagtaac
    27181 agttagtgaa gtagaggaaa gcaactgggc aacagcctgg aagaaatact atcatccggt
    27241 gcgtattacg cgaatgctga cggttgcgcc aagctgggaa aactaccaga cagaagatcc
    27301 tctagaaaaa attatcacac tagatcctgg tatggcattt ggcacaggca ctcatcccac
    27361 gacttccttg acattgacag cactagaaac agtcttgcgt ggtggtgaaa cattgctaga
    27421 tgtgggaact gggtcgggcg tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt
    27481 ctatgccttt gatttagacg aagtagccgt tcgttcggcg aaagaaaata tggatatgaa
    27541 tgaaatagcc aaagatgtcc atgtatcagc taacgatctt ttgacaggaa tcgagattga
    27601 aagtgatgta atcgttgcga acattttagc agatatcatc ttattgatga tcccagatgc
    27661 ttggcgttta ctgaagcaaa caggcacgct gatcgtttca ggaatcattg aagagaagaa
    27721 gcaaatggtt ctggatgcca tgttagaaca agggtttatc gtggatcaaa ttttccagca
    27781 aaaagactgg tatgcaatta ttttgaaaaa accagaggtg gaatagatgc agcggtattt
    27841 tttaaaagaa tcatatgaat caaaagacta ttttgtttta gaaggggaaa actatcacca
    27901 cattgtacgg gttatgagga tggaacccga ggatgaagtt tttttggcat tcaatgatca
    27961 aatagccatt gttgcagaaa tcacggagat tactgaagag gctgtttatc tgaaagaaat
    28021 taaaaaagaa gaaaatcaaa aggaactgcc aagttcgatt accatagcga gtggctatcc
    28081 taaaggggaa aagctggatt ggatcgttca gaaatccact gaattaggag cgcaagcttt
    28141 tcttggtttc ccggcatcag cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg
    28201 acaacaacgg cttgaaaaga ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt
    28261 gccatcagta gagttattgg aaacgaaaca agatttattt gagcggctag atgattatga
    28321 cgtggtcttg gttgcttatg aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa
    28381 aattcttagt gaaacaaaac cagatagtcg aatcttagct gtctttggac cagaaggtgg
    28441 attatcccgc gatgaagtcg attattttgt agaacacaaa gggatacttt gtggattagg
    28501 accaagaatc cttcgtacag aaacagcacc tctttattta ttaagtgctg ctagctatca
    28561 atgggaatta atgaatcctt ctttcagcta acgttcttca ttaataaaag agtatcgaca
    28621 gaaagaattg aaaaaatagt caacaatttg tataatagaa acaattattt atacaatgga
    28681 tacgaaaaat cgtttgaaaa agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa
    28741 ctgcacggat tttgggacaa ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa
    28801 aaaagaaagg gggatcgatt cctgtgacaa aagaagaaat tttaacggga cccggtgtca
    28861 taaagctcgt tagtcaatac atgggtcccg aacatgtagc atttgttgag aaagcatgcg
    28921 aatacgcgac tgctgcacat gacggacagt ttagaaaatc aggcgaaccc tacattattc
    28981 atcctatcca agtcgcaggt atattagcag atttaaaaat ggatccccat acagtggcta
    29041 caggcttctt acatgatgtt gttgaagata cagaaatcac tttagaagat ctgagagaag
    29101 aatttggcga tgacgttgct atgttagtgg acggcgtaac caaattaggg aaaataaaat
    29161 ataaatccca cgaagagcag ctagcagaaa accaccgaaa gatgctgcta gcaatggctc
    29221 aagatttacg agttatcatg gtcaaattag ctgatagact acataacatg cgtacgttga
    29281 agcacctgcg agaagataag caaagaagga tcgctcagga aactttagaa atctatgcgc
    29341 ctcttgcaca tcgtctaggg atcagccgga tcaaatggga attagaagat acagcacttc
    29401 gttatctaaa tccaaaacag tattaccgta tcgtccactt gatgcagacg aagagagaag
    29461 aacgtgaaaa atacgtaagt ggtactgttg aagatattcg aatagcgaca gaagagctgg
    29521 ggatttttgc agaaatctat ggacggccaa aacacattta ttcaatctat cgtaaaatga
    29581 aagatcagaa aaagcagttc aacgaaattt atgacttgct agctattcga gtgatcgtag
    29641 attcaatcaa ggattgttat gctgtattag gagcaatcca cacaaaatgg aaaccaatgc
    29701 ccggcagatt taaggattat attgccatgc caaaagctaa tatgtaccaa tctttgcata
    29761 ctaccgtgat cggtccggca ggaaatccgg tagaaattca aatccgaaca caggaaatgc
    29821 atgaaatcgc tgaattcggg gttgctgcac actgggccta taaagaagga aaaaatgaaa
    29881 aagtagaacc agatggtatg acgaaacaat taagctggtt ccatgagata ctcgaacttc
    29941 aagacgaaag ctatgatgct tctgaattta tggaaggcgt aaaaggagat atctttagtg
    30001 ataaagtcta cgtcttcaca ccaaaaggag acgttactga gttaccaaaa ggatccggac
    30061 cattggactt tgcatacagt atccatacag atatcggtaa caaaaccact ggtgcaaaag
    30121 taaatggcaa aatggtgcag cttgattaca aattgaaaaa cggagatatc attgagatca
    30181 tgacttctcc aaattcattt ggcccaagtc gcgactggtt gaaattagtt gctactagca
    30241 aagcaagaaa taagatcaaa cgtttcttca aagcccaaga tcgagaagaa aatgtgatca
    30301 aaggccacga atccgtggtc aaatgtatta cagatctagg atttacgcct aaagatattt
    30361 tgacgaagaa caaactgcaa gaagcactcg atcgttttaa ttatcaaaca gaagatgatc
    30421 tctatgcagc tgtagggtat ggagaagtta gccccttgac gatggccaat cgtctgactg
    30481 aaaaagaacg taaagaacaa aaaatcgagc agcaaaagca agaagcagaa gaaatcatga
    30541 atcagccgaa aaaagaacct gacaaaatga aagtacgtca tgaaggtggc gttgtcattc
    30601 aaggggtaga aaacttacta attcgtatca gtcgctgctg taatccgatt cctggtgatg
    30661 atatcgttgg ttatatcact aaaggcagag ggatatccat tcatcgtcga gattgtccga
    30721 atgttcagcc tgacaaacca aatgtagcag aacgtttgat tgaagtcgaa tgggaagata
    30781 catcgaatac acgaaaagag tatgatgcag atttggaaat ttacggctat aatcgttcag
    30841 gcttattgaa tgatgtactt caaacagtca atgcgctaac gaaaaatctc aacagcgttg
    30901 aagcacggac gaataaagat aaaatggcga cgatccattt gacggttggt atccagaatt
    30961 tatcccacct aaagagtatc gtggataaaa tcaaagcagt acctgatgtc tacagtgtac
    31021 gccggacgaa tggataggag gacagatatg agagcagttg ttcaacgggt aagtaaagct
    31081 gctgtgtcag tcgatcagca agaaattgga aaaattggct acggcctact tgttttatta
    31141 ggcattcatg aaaccgatac gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa
    31201 atgcgtattt ttgaagatga acaaggaaaa atgaatatta gtgtagaaga tgtgggagga
    31261 caaattttaa gtatctctca attcacactg tttgcggata cgaaaaaagg aaatcgacca
    31321 agctttgtgg aagccgcacg accagaaaca gctattcctt tatacgaatc attcaatgaa
    31381 ggaatcagaa gtcgcggcat cacagtcgct accggacaat tcggagcaga tatgtcggtt
    31441 tctctcgtca atgatggacc tgtaacgatc attattgatt ctaaaaacaa ataaagtaat
    31501 ctggttttca ctagtaaaaa ctatgaaaca cgtcgcttaa gttagactga taaactctaa
    31561 cttaagtggc ttttttgtct gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt
    31621 aagcttaaat tatacaagtt attttttata ggaggttgct gaagatgaaa gaagtaccag
    31681 tagtagatat caaaatcaca gatttaaaaa aattgtatca aaaaggatac aacatgttgg
    31741 aggagttacg ccatgaagcg gacgctcccg tcgtcaaagc aaagattttc aataaagaag
    31801 ctatcacgat ctacggatca tcagcagcaa aagtatttta tgatccaagg aatttcaaac
    31861 gaaaaggtgc tatgccaaaa ttagtattga agacactttt tggtcaaggt ggagtacaga
    31921 ctttggatgg agctgctcat caccatcgga aaaatatttt tatggatcta atgacaccgg
    31981 aaagaatgga agattatcat cgtatcttag ataagaatct gacacaagca cttgaagcac
    32041 agcatggtca atttgaacta tttgatttaa gtaagatggt tttctttaca tctatttgcg
    32101 agtgggcagg tatcaattta tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat
    32161 atcaaatctc tatgatcagc ggaacgttta cttctccgat tgatcacata aaaggtgtcg
    32221 aaaatcgcaa aaaatcagaa aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc
    32281 ctgtggctgg aaaagaaaat gtggcattat atgcttttgc caatgccaca gatttagatg
    32341 gtcagctttt acctctggaa gtggcagctg ttgaattatt gaacatcatc cgtccaacgg
    32401 ttgctctaac tgtgtgggcg gcattgatgg gacatgcact tttcagtaga ccagatttgt
    32461 atcagcaatt aaaaaatgac ttttcgacgt tacaagatcc gtttattcaa gaaatgagac
    32521 gctattatcc tttcttccca atgctacctg cgatttcgct gaaagaagta gaagtagatg
    32581 gttatcgtat accagaaggc agttgggtta ttttagattt atatggaaca gaccatgatg
    32641 aacgaacagt tgaagcgcca gattccttta tgatcaaacg gtatgtaggg aaagcaaaag
    32701 atatttccta taaagaagaa tatgagatga ttgcacaagg cgggggaaat tttcgacaaa
    32761 tgcatcgctg tgcaggagaa tggatcactc ttcatagtct acgtgtgttt tccgatcagc
    32821 tagtaaataa gtttgagttc tctgtacctg aacaagattg gacgattcca ttcaatcagt
    32881 ttccgactta tccgaatagc cgagcgctac tttacaagaa ttagattagc ataaacttat
    32941 cgaaaaaaag gaagatcaaa cagtgctgat cttccttttt tcatattact ataaattgat
    33001 aaggtcaatt gatcaaaatc cacgaaatgc ttcatcaatg gtttgataat cttcattgga
    33061 taaatgcaaa tctaaagctt ggacattgtc agatacttgc tctggacgct tagctccagg
    33121 tataactaca gacactcgtg gattcttcat gtaccaagct aaaacaagtt gcgcaggagt
    33181 ggcttggtat cttttagcaa tggggcgaag tacatcgaca gcggttaaaa tttctctgaa
    33241 acgttctcct tggaaatctg gatttctttt tcgaggatct ccttcaccaa attgtttttc
    33301 ctcaccaagt tcatattttc ctgtcagcaa accggaagca agaggaaaat agggaacaaa
    33361 actgattttg tttttttcaa gataagggaa taattctttt tcagcctgcc gatggatcaa
    33421 actgtattta tcttctacta catcgacata tccatctgca ttcgcttctt tcaattgttc
    33481 taacgtgaag tttgacacac cgactgctcg gatttttcct gcttctttta attcgtgcaa
    33541 tgtagcaact gattcatttt ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc
    33601 gatgtaatca gtttgcagac gttttagtgc atcttccacc gattgtttga gaaactcagg
    33661 agaattatca aatgttcgcc ctttatttgg tacatgagca gcttttgtag cgatgacgac
    33721 acgtgagcga tcatattctt tttccttcag tacctcgcca atcagttctt cggaacggcc
    33781 gtttccgtaa gcataagcgg tatcgatcaa attgatcccg ctattcaaag ctgtacgaac
    33841 tacttgtttt cctgtctcat cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt
    33901 tgctcctaat ccaagctgtt ctgcgtagac ttgtgaatgt ccgattctta tttctgccat
    33961 agctgattcc tcctttttgt ctagtctaaa acaaaatacc aaaaagctga actaaaacgt
    34021 ttttgtgagg ggaaatagtc agatatctct tgactttgag actggttttt agtaggttat
    34081 aagtaatatc gaatgtcaat gaaagagcga gtaagttttt gaaactttac aagagaggat
    34141 catcgaggct gaaaatgatc taaagtttca ttagcctaaa gacactctgg agatggacga
    34201 gtgaaaagcc gtcccgcgta cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat
    34261 taggtggtac cgtgtatgaa tttcattcac ccttgttcat gatgaacaag ggtgattttt
    34321 ttatttacat agctaagaaa gggagagaaa actatgagtt tccaaagacc aaaaggaaca
    34381 aatgatattt tgccaggcga atcagaaaaa tggcagtttg tcgaagaaac agcacgttta
    34441 ttattcagag attatcagta taatgaaatg cgtacaccga tttttgaaca ctatgaagtg
    34501 atatcccgaa gtgtagggga tacaacggat atcgtttcaa aagagatgta tgatttttat
    34561 gacaaagggg aacgccatgt gacgcttcga ccagaaggta cagcaccaat cgttcgttct
    34621 tttgttgagc ataaattgtt cggcccagag tatgcgaaac cgttcaaaac tttttatatg
    34681 ggaccaatgt ttcgctacga acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc
    34741 ggagtagaag catttggatc agaaaaccct gcaactgatg tggagagcat ggtgatggca
    34801 cttgatttct tcaaacagtt ggggatcacg caaatccggc tagtcatcaa ttcattaggt
    34861 gataaagaaa cgcgtcaagc ctatcgtcaa gcattgatcg actatctttt accttttgaa
    34921 tcagagctga gtgaagactc taaacgccgc cttcatgaaa atccattacg cgtattggac
    34981 agtaaagaca aacgagatca aaaatttgtg gcagaagctc catctatctt agattatcta
    35041 agcgagcctg ctcaaaaaca ttttgatacc gttgtttcca tgctggatgc attggctgtt
    35101 ccttatgaaa tcgacagtaa tatggttcgc ggactagatt attacacaca tacgattttt
    35161 gaaatcatga gtgacgcacc aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt
    35221 tatgacaatc tagtggaaga actaggtggt ccttcaacac ctggcttcgg atttgcaatg
    35281 ggtatcgagc gattactctt gactatggag gcagaggaag tagttatccc tgcatttaat
    35341 gagttggatg cttacgtggt cgcactcgga gacgaaacaa atatcgaagc attgaaagtg
    35401 gtccaagcga ttcgaaactt tggtttttca gctgaccgcg acttcatgaa ccgtaaagca
    35461 aaagcgcaat ttaagacagc agataaagcg aatgccaaat tagtattggt gatcggtgaa
    35521 gatgagcttg ctagtcaaac gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt
    35581 tttccattag aagagatata tgaacatttt gatgaagtct atgatgaaat gactttattc
    35641 gagtaggagg aaaaaaataa atggcacaaa gaacgatcta ttgcggatta gtttccgaac
    35701 aacaattaga acaaacagtt acattaaaag gatgggtaca aaaaagacga gaccttgggg
    35761 gagtaatctt tatcgaccta cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg
    35821 aaatcaacaa agaagcatgg gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag
    35881 tgactgggga agttagaaga cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg
    35941 aattcgaagt gattgcaagt gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc
    36001 aaattgaaga tgatcaagca atcagtgacg aaatacgttt gaaatatcgt tatttggatc
    36061 tgcgtcgtcc aaaaatgact aaaaacatca aattaagaaa tgcgacaaca agagcgattc
    36121 gtcattattt agatgataat gactttctcg atatcgaaac accttaccta gggaaatcta
    36181 caccagaagg cgcaagagac tacctagttc cttcacgtgt ccatgctgga catttctatg
    36241 cgttgccgca atctcctcaa ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt
    36301 attatcaaat cgttcgttgt ttccgcgatg aagatttacg tggagaccgt cagcctgaat
    36361 ttacgcaagt agatattgaa acaacgttct taacagcaga agaaatccaa acttacacag
    36421 agggattgat tgcgaaggta atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc
    36481 ctcgtatgac ctatgatgaa gcaatggctc gctacggcag cgacaaaccg gatacacgtt
    36541 ttgatatgga attgatcgat ctaagcgata cagtcaaaga agtagaattc aaagtcttcc
    36601 aaatggctct tgaaaacggc ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc
    36661 gctactcacg aaaagacatg gatcagttag gtcaatatgt aggacaattc ggagctaagg
    36721 ggcttgcatg gctgaaagta gaagaagacg gattgaaagg tccaattgct aaattcatgg
    36781 gagaagcaac agaagcaatc attaaagcaa cagatgcaaa accaggtgac ttgctgatgt
    36841 ttggcgcaga taaaagtgaa atcgtcgctg ctgcattagg tgctatccgg acacgtttag
    36901 gaaaagaatt aggactaatt gatgaatcga aattcaattt cttatgggta actgattggc
    36961 cacaatttga attttcagaa gaagaaggtc gatatgtctc tgctcaccat ccattcacga
    37021 tgccaaaaga agaagatatc ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag
    37081 cttatgatat cgtcttgaac ggttatgaac taggcggagg ttctatccgt attcatactc
    37141 gtgagcttca agaaaaagta ctagaaactc taggctttac aaaagaacaa atggaagaac
    37201 aatttggttt cttgttaaca gctttagatt acggattccc tccacatggc ggtattgcat
    37261 taggattgga ccgttttgca atgttattag ccggagaaga taatattcgt gaagtcattg
    37321 cctttcctaa aaacggaaaa gcagcagatg tgatgagtga tgcaccaagt atggtttcgc
    37381 ctttacaatt gttcgaattg aatattgatg taacgaatat agaagaatag ccgataaaaa
    37441 ggtaaaaagg atttgtcgaa tacgcttctt ttgacaacct tgatttaatt gaaaaacact
    37501 ttataatgaa gccataacat ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt
    37561 gggcttatca tgattacacg accaagcttt cggtatctat cgtttatgcg ttgatcgcat
    37621 cagtcgcatt gaatttcttt tatcagccag gacatattta ttcaagtggt attactggtc
    37681 tagctcagat tttgacgact ttgtcaaaat cactgatagg attcgaagta ccggtatcaa
    37741 caactttgta tttactgaat atacctttgt ttgtattggc gtggttaaaa atcgggaaga
    37801 agtttacaat tttcactttt atcacagtca ctttgacctc cctttgtatc catattttac
    37861 cggaaacagt cctatctacc gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg
    37921 gactaggtat tgggctagcg ttgagaaacg gcctatcatc gggcggtcta gatatcgtga
    37981 gtatcacgat tcgtaaaaaa acaggaaagt cgattggttc tatttcgatc tacttcaatg
    38041 cattgatcgt ttttgttgcc ggaattctat ttggctggca atatatgttt tacagtacgt
    38101 tgtctatttt cgtcagtgga aaagtaactg atgtcgttta tactaaacaa aagaagatgc
    38161 aggtaatgat cgtaacgaaa catccagaaa aagtagtaaa tgaaatccaa aactgtatgc
    38221 gtagagggat cacgatcatc aatgaagcag aaggtgctta taagcatgat aagcagacag
    38281 tattgatgac gatcgttaca cgatacgaac tgcctctact tagagaagca atgaaagctt
    38341 ctgatccaca agcttttgta agtattgcag aaaacgtcca gatacttggt cgtttctatg
    38401 aggatggcat ttagatcgag tttgacaaaa attcatgaaa tactgctgta gacagacgtt
    38461 cgtttgtctg cagttttttt ctaccatagt agaatcagca aagaaaaact gcttttttat
    38521 ttgaaatttt cttaaagttg aaaaaaagca tgtttatttt tttaaattta tgggatgata
    38581 gaaaaaaata gtagagaaag gacacgattc tacttgctat tttcacttaa tacccgtata
    38641 ttacgaatga aaaaagttta tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta
    38701 aaaaacagcc gctacatcac tgggtttgat gggctccgtt cattagctgt ggtgggtgtt
    38761 atcttctatc accttctgcc aactagtatg aaaggcggct atttgggcgt tccgattttt
    38821 ttcgtcgtat ctggttattt gatcacggat ctgctgcggc aggaatggga acaaaatgga
    38881 aaaatcaata tttggcaatt ttatgtcaga agaatgaaga gactctatcc ggcacttgtt
    38941 tttatgcttg tgacagcttc ggcttatatc actttgtttc agcgagggct gttaaacaat
    39001 cttcgaggag ttgtggtcag cagcttactg tatgtcaaca actggtggca aatcaataac
    39061 ggtttatctt atttcgatcg atttgctaat gagtcaccgt ttacgcatat ctggtcttta
    39121 gcagtagaag gtcaaaacta tttggtttgg ccgatcttgt ttgtattgtt gatggtattt
    39181 gttcgtaaaa gaaaatggat cttttatact gtgttaggta catccttcct ctccgccatc
    39241 ttgatgatga tcttgtatac accaggaggc gatccaaccc gtgtttatta cggtaccgac
    39301 actcgtctgt tttctatatg gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt
    39361 ttaaagaaaa acatcccgaa acaagcgaaa aatattctga atatcgctgg aggaatctcg
    39421 cttttggcac tgattctttg cttcttcttt ttagatgatc attacaattt catctattac
    39481 ggaggaatgc tcctagtgag tctgttatgc gtagtgctag ttgcagtgac agcacacccc
    39541 ggagcaagtt tgaatcgatg gctgacaaat ccagtattta cttggattgg caaacgaagc
    39601 tatggcattt atctgtatca gtttccagtt atgatttttt atgaagcaaa ggtgactgat
    39661 attgccgatc atgttttgtt gcatacttta gtggaaatca cattgattct aatcatcagt
    39721 gaactttctt atcgatatgt ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc
    39781 caagtgatga aaggatggtt cagcaaaccg atcatcagta agagcaaacc atgggttgtt
    39841 ccaggcacat tacttgtagc aattgcactc gttggtttcg ttacggcacc gaaaaacgct
    39901 gtaacagccg atcaaaaaca actgcaggca aaaatcgctg aaagtaaaaa attagcagaa
    39961 gaaaccagaa acaattcaga aaacaccact agttcggttg accaagcgat ccttgataag
    40021 tacgagttgt ccaaggcaca agggaataag gcacaaaaat tagaactaac ggcatttggt
    40081 gattcagtta tgttggatgc tgcaacggat ctacaagaac tttatccaaa agtagtggta
    40141 gatggagatg tcggacgaca attatatgcc agtgtaccgt acattgaaaa attaaaggaa
    40201 caagatttgt tgaaagacac tgttctgatc ggactaggaa cgaatggctc attctcggaa
    40261 gctcagtttg atagtgtgat ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc
    40321 cgagtaccga cgaagcgctg gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa
    40381 aaatacgaca atatgacgct gattgattgg tacagctaca gtaatgacca tagtgactgg
    40441 ttttatgatg atcaagtcca tccaaatcct gaagggatga cacattacat tcacttagtc
    40501 agcgaagcct tgctaggagg aagttcaagt acgaacagca gtgagacaaa cgtgacagaa
    40561 tgatagctac aaaaaacttc aggcaaaaac atttgttttt gcctgaagtt tttttatatt
    40621 taccgtgttt ttaacattca tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa
    40681 taacgttctt tttgttttcg ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg
    40741 cttcttgaag aaaatacttc tgcatggatc atcttaacag gtcttctttt ttgaagacga
    40801 gtatatttag caccagtacc attgttatgt tcctctaatc gtctagaaag atcggttgta
    40861 tatccaccat aaaatgtctg atctttacag aataatacgt aaaaataatg ttcatttgcc
    40921 atagagcatc tcacgaatct ctgcagtgta ttctccatcc atattgtaag tgatcaatgg
    40981 tggagcgact ttgaatccgt ctaatttgcc ttctttgatt ccttcaacta acaaaatatt
    41041 tgcctctttt ccaggttttg ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc
    41101 ttccatgacc tgaatgattt ctaagaaccg atcaggacga tggaccatag taaagcgtcc
    41161 atttgttttt agtagcttac ttgaaatatc gatcacttct tctaacgtcg tatgaatctc
    41221 atgacgggcg attgccaggt gtttattagg gttcgtttta tttgttggca gccctttgaa
    41281 ataaggtgga ttacagacga ctaagtcaca agaattatgt cgaacgacag ataagctgtc
    41341 tttcagatcg atggtgtgga cagtcatttg ttcatttaaa tggttaagcg cgatactacg
    41401 tcttgccatg tctgctagac gaggttgaag ttcgatagcg tcgatagccg cctgggttcg
    41461 tttacttaaa aaaagtccaa ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt
    41521 tttaggtaca cgggaaaagt gagcaagcag cacagcatct aaagaaaaag aaaacacttt
    41581 ggaactttgg ataatcttga tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg
    41641 aagcatggat tccctccaaa atgaaaaaaa tagtcgtctg tattatacta tttttattaa
    41701 aaagaaccaa ggtggcttgt caaacctcta ttttttatgc atactatgac cataagaagg
    41761 gaaaggaaga gactatgttt tatcgattta tgcgcggggt agttcgagta ctattagcct
    41821 tagttaatgg aaatgcccgc tatgagaata aagaagtttt accgcaagat gagaattaca
    41881 tactagttgc tccccatcgt acttggtggg acccattata tctggcggta gctgcagcac
    41941 ccaaggaatt cagctttatg gcaaaagaag aactgttcaa aaatccagtt ctgcgattta
    42001 tattaactcg atccaatgct tttccagtta aaagagaaaa tccaggacca agcgtcatta
    42061 aaacacctgt aaagattttg aaatcgacaa atttgagttt gatcatgttt cccagtggga
    42121 caagacatgc tacagaactt aaaggcggaa tggcattgat ttccagaatg tctaaagcga
    42181 aaatcgtgcc agctgtatat caaggtccgt tgacacttgg ggatctgttc aagcgtcaga
    42241 gagtgacagt gcgtttcggc gaaccaatcg acttatcaga tatcaagaaa acggataaag
    42301 aaggtatggc ggagatcgaa cgacgaacac aagcagcttt tgacaaattg gacaaagaag
    42361 tgaaccctga tttcaaatat gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc
    42421 ggtcttttga atctactgtc ctgttcagtt cagacttttt caatgaaaac gagggagaga
    42481 cgtcaagtct gccctctttt tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa
    42541 tggatcaaag tgttataata attagaagga cattttttga ggtgattgaa tgcgtttttt
    42601 acatacagcc gattggcata tcggaaaaaa actacaaggt tatgacttga ttgaagacca
    42661 gcgtcatgta ctatcttcta tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt
    42721 gattgccgga gacttatatg ataggagtgt cccagctgtt gatgccgtag aattatacaa
    42781 tgaattgatg gtcgattgga atttaaagga aaagatcccg atttttgcta tatcaggaaa
    42841 tcacgatagc agtacgagac tttcagcggg tacgccatgg ttcagttatt cgaactattt
    42901 tttgcgaaca cagctagcag aagcatttga accagtcgag tttaaaaacg tacaattttt
    42961 ctttcttcct tactttgaac caattgcagc gagattatat tttgaagatg acaatatccg
    43021 aacgatcaag caagcggtag ccaaggtgat agataaaatg caggagctat ttgattcaga
    43081 aaaaaaacaa gtattgatta gccatttttt tgtaatggga agtgtaaaat ctgattcgga
    43141 aacgaaaatc gaagtaggcg ggttggattc gatccctggt gaactactta caccgtttga
    43201 ttatgtagca ctaggacatt tgcataatca agctgctttg agacaggata atgctcgcta
    43261 tagcggttcc ccattgaaat tctctttatc tgagatcaac caaaaaaaag gcgtatggat
    43321 cgttgacctg acaacaggcc tggagttgaa ttttagggag atcgaacccc tgcatgatat
    43381 tgaagaaata acagcgagtt tcaaagaatt gctggatcct gccttttatc agtccgtcaa
    43441 tcgggagaat tacatctata tctatctcac tgatagaacg atcatcccga atatgatgaa
    43501 ccagcttcgg caaatatatc ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga
    43561 acaaacaaag cgcaaacgaa aagtactaga aatgaaagat cctcaaaaat tagcagaagc
    43621 attttttagt gaaatgacgg aagagcagct aactgcaaac caagaaaaat ggctcggaga
    43681 aacgttgcaa gaaatcatgg aaatggaatg atcaagaatg aaaccgaaaa aattacaact
    43741 taaaaatttt ggtcctttta tcaatgagac cgtagatttt tcacgtttga cagaagcacc
    43801 gctttttttg atcagcggga agacaggagc tggcaaaacg acgatttttg atgggatcac
    43861 cttcgcactt tttggtgaaa cttccggaag acttcgctct ggaaaagaga tgcgttcttt
    43921 gtttgctaca ccagacgaag aaacaagcgt gactttttct tttgaacatc agcagatgag
    43981 ctatgaaatc gaacgaaaac cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa
    44041 aaaacaggca gccaaagtaa cgttgaccat ttttgatggg aaaggaaaag aaataaaaca
    44101 aatcacaaaa cgtacagaag cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa
    44161 acagttttct caaatcgttt tactacccca aggagaattc cgtaattttt tggtttcatc
    44221 aagcagtgat aaagagactg ttttacgtca tttattcggt actcaatttt tccaacagtt
    44281 caatgagcga ttaaaagaaa aagcaaaaca acagcaacaa aaattggatc atttagagca
    44341 agagctgcat cttctgcaaa aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg
    44401 gtttgaagcc gttttagccc aatggacaaa ccatcaggca atactcgaaa aacaaatcac
    44461 ggaagaaaaa gaagctctaa cggaacttca ggaaaaacaa aagcaactag aaaattccta
    44521 ctatcgtttt gaaagcttga aaaaaagtta tgaagaaaaa acgatattaa taaacaagca
    44581 aaaggaatta gctgctcaaa aagacgaaat agaggaaaag aaacgatgga ttgggtatta
    44641 tgaatttacg caacgattag tcgaaccaat ccagcgccta caagaaataa aagttgaaaa
    44701 aatagaactg tcacaaaaaa gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa
    44761 ttatgaagag tggcaaaaaa atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga
    44821 agctgctcaa aaactgcaaa acaaacagat gatggtgcca attgtcgaat ccttacgtag
    44881 taaaaaacaa gacgcagaac aattaacaat ttcattggat aaagaagaat tgaatgccga
    44941 gaagctgtat caaaatctcg ctatctatca ggaaagaact cgaattcttc aagaaaattt
    45001 actggatcag gaaaaactgc aagaagatcg tcttgctttt ggacagttaa aatatctaga
    45061 tgaaaagcag caagaaatag aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat
    45121 aagagaagaa ctcaaaaaag caactgaaga aataacaaaa aatagtcagc tattgaaaga
    45181 acagacagaa caagcagaac agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct
    45241 tcagcttttt ttgcgtccag gggagccatg tcttgtttgt ggatcaacgg aacaccccat
    45301 acaacaatta aaacacgaac agccaaataa ggaagatatc ttaaaagtag aacaacaact
    45361 ggcagaagct gagtctgctg tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca
    45421 tgaaaataat cttcaacaac aattatcaga tttagaacaa aaaatcatgg caacgaatat
    45481 acaattggct gaacaagaag aacacttgca acaggctttg aaaaaggcat ttcctgagat
    45541 aacagaacaa aaaacaaaaa caactcttgt agtaatcgaa caatctttag atagacgaaa
    45601 aagcaagatg gccaatgcaa gaatagagct ggaagaaata agacaacaag cagaaaagct
    45661 cgaacaacaa ttagctgtct acaaacagca gcagacagaa aaaaataatc agctccagca
    45721 actgcaagga gaaatcaaaa gtttagaaca acaattgcaa gatacggata gtaactgttt
    45781 agaagaggag atacgacgac ttgaaaaaca gttagaagaa gactcgaatc aactagctgt
    45841 tgagcagaaa gcaggagtgc aattgttgca agatcttcat acgcttcgga cacagcttga
    45901 tcttcaacat gaacaaatag aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat
    45961 agctaaaaag ttagaaagcc agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc
    46021 acaacagcaa gcacaatata aagaaaacca acgtacagtt acttcttatc atgaagagca
    46081 attagtgaca gctgaccggc tgcgtcaatt agaaaatatc cagctaactg agacattccc
    46141 agatacagaa gagatcagcc aacagttaga agaaataaga cgtatgatcg aaataaagca
    46201 agaaaagata tacggtttac aagaacaaaa aattagtaat caaaaaatct acgatgaatg
    46261 tctttcgatt tatcacacaa gccagacgaa attagatgag cttacgcaat tacagcagct
    46321 ttcgcaaaca ttcaacggag aaaatcctaa gaagactagt ttggaacggt atgtgcttca
    46381 ggtttatctt caagaagtgt tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa
    46441 tcgttatcaa tttgagctag cggataccat tggcagttat cgagggaaaa ccggattaga
    46501 aatcaatatc tatgatgatc aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg
    46561 tgagagtttt attgcagcac tttctttagc attagctctt gccgatgtga tccagacaca
    46621 agctggtggt gtagcaatcg atgcattgtt tattgatgaa ggatttgggt cattagatga
    46681 agaagctttg gaaatggcaa tggaagcttt agaaacgatc gaaagtgaag gaagaatgat
    46741 cggcatcatt agtcatgtaa gagaattgaa agaacgagta ttacaacaaa taagaattga
    46801 tacagaaggt agcggacaaa gcaaaatacg ctatcaactt ggataaaaag ggagattggt
    46861 aactatgaaa tggagtattc cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga
    46921 aggccgagtg ttatcggttg tccctgacca agaagaaaac gtgtggcatg cagaagtctt
    46981 gggcagtgaa ttgtatatgg ttgatttgga tggtacagca aaagagatag attactgcca
    47041 atgtccctat tgggaggaac ataaatattg taagcataca gttgctgtgg aactttattt
    47101 acggtcgaaa aatctatctc gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa
    47161 agcaacaagt gagggagaaa tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa
    47221 tcctcaagcg gtgcaacctt tgattattga ataccaagta gaaacgattg agactaatca
    47281 gtatcaccca gagctttcta ttttggcact ttacttgcgt atcggttcat tggcatcacc
    47341 gaaaaaaaca tatatcgtaa aaaacatcta tgatttttta caagcttaca cagaaaaaga
    47401 aacttacact gttaataaac agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga
    47461 agatcaaaaa atactcacgc atcttgcagg aagtgctcag acgcatcaat tattaggtac
    47521 gaacggctta caagtcaaag gaaaactaga taaaagatat ctgcttctcc cagtagaaca
    47581 agcccgcttc ctgttagagc agatgaatca gactacacgt ttgcatctgc agataaatga
    47641 acaaaacgat caaggaatac aattttccga tcaaaacaaa cctttatcat tcaaagtgga
    47701 aaaatttgga gaagattatt tgctgcaagc attgaatgat tttgattttt tctttatgca
    47761 ttatcagtgg ggagttatcc aagggacatt ttattctctg acgaaatatc aacaaacggt
    47821 ttatcaaact tggaaacaat tgattcgccg attggagaaa ccagaagtag tgttcaagaa
    47881 aaaagaatta ccgtctttgt ttaaagagat tatccctctg ctgtcagaga tcggcgacgt
    47941 agctattgcc cctgcagtag aagaggaagt agcagatatc cccgtcgaat ttattttctt
    48001 tttccgaaaa gcaaaaggaa aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat
    48061 ctattcgact gacccgaagc atgaggtctc gacagaacag gcttttcagg tgttacgtga
    48121 cacagtagaa gagaaacgag tacttgatct attcagaatg tatcgctacc agaaaaatga
    48181 aactggttat gaacgtccat tgccaagcgg ggaagaacta tatgcctttt tccgcacaga
    48241 actatctgtc ttccgtcagt ttggtgaagt cagacttgga agaaaattgc gagagttgta
    48301 tttagatgcg cataaacatc aaccgaaaat cgaagtaacc gagaccggtt catggctcga
    48361 tattcgattc gatgtgacag ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt
    48421 gctgagaaat gatgcttttt atacattaga aaatggtcag gttctttctt ttgattcaga
    48481 agaatttcaa caaacaagcc aagtgttgca acaattacgg gaatcgatac gtacagaaga
    48541 aggaacgatc catgtaccta aaaatcaagg attgatcatt caaaatcaat tggaaaaaag
    48601 caatgctact tttagtgaat cgttccaaac gatggtacaa gatctcattc atccagaaag
    48661 ataccaggca cagcttccca aaggattgaa tgcaacgatg agagattatc aaaagcaagg
    48721 ttttcgatgg ttgaagatgt taggtcatta tcagtttggc ggtattttag ccgatgaaat
    48781 gggacttggg aaaacactac agacaattgc ctttttactt tcggaaaaag aagaacggaa
    48841 aagcttctct gctttgatcg tagcgcctgc gagcttaatt tacaactggc aggcagaggt
    48901 gagaaaattc gccccttctt taagtatcca agtaatcaat gggaataaaa aagaacgtga
    48961 agaattactg gctaaagaca cagatatccg agtgacttct tatgccagct taagacagga
    49021 tctagctaat tatcagtcgc aaaaaattga ttatttgatt cttgatgagg cacaaatggt
    49081 caaaaatagc agtacgaaaa ctgcacaagc attgagagaa ttagctgtac ctcagcggtt
    49141 tgcactgagt gggacaccaa tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac
    49201 gattatgcca ggatttttcc cgactaaaac aaaattcagg gaacttgccg cagaagaaat
    49261 tgcgcaaatg attcgaccgt ttattttacg gcgagataaa caaactgtgt tgaaagactt
    49321 gccggaaaaa acagagatga atctatattc tgcacttaca gaagaacaaa aaactgttta
    49381 tttagcttac ttgcgtcaaa tgcgtgaaga aatcacatca atggattctg aagcattcaa
    49441 gaaaaaccgg atcgggatac ttgctggtct gacaagactg cgacaaattt gctgcgatcc
    49501 tcgtctgttt attgaagatt accaaggcgg ttccggcaag ctcgaacaag taaaagatct
    49561 actggtagct gccaaagaga acaaacgaag agttttgctg ttttctcaat ttacagggat
    49621 gctgactatc ttgcaagaag agttagccga gctagggatc tcgacatttt atttaagagg
    49681 cagtacgaaa ccacaagatc ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga
    49741 tgtttttctg atttccttaa aggctggggg aactggattg aatctcacgg gagcagatac
    49801 ggtcatcttg tatgaccttt ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc
    49861 acatcggatc ggacaaaaaa atgtggtaga agtgtggcgt atgatctctg aaggaacgat
    49921 tgaggaacgc atggattcac tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca
    49981 aggtaatgaa gaacagttga cgaaactgac tgaagaagac atccgcatga ttttaagtgt
    50041 aggagaaatc gaggagtaag agactcgaaa aagcgttcag taatgggtaa gaaagccttt
    50101 ctaaagaagc gattgtttat ttgatttaaa aaatagcaag gaggctggga ttccatttta
    50161 tcccagcttc cttgctatca tttttttatt tctattttta aaggttatac aaagattgtc
    50221 ttcattgtct ctaacagctg atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt
    50281 tcaattttgc gttctcgatg gttgaaccaa agcgcttgcc agttagcact ttttgcacct
    50341 agaacatcat tgtcgtaatt atcgccaacg tataaggtct cttctggaag catatgaaat
    50401 tctttctcag ctagctgaaa aatctctttt tctggttttt ggaaacctgt tgcttgagaa
    50461 atgagcatat tgcgggaagg aatccaattg ttcaattgaa gttgcttcag tttttttgtc
    50521 tgatggtcag tcggcccatt tgtgataatt cctaatggga cattcttttc cttcaagaaa
    50581 tcgagggttt ttttgacctc ctcatgcaag cagatattat caagttcttc ctcgtaaatt
    50641 ttttgaaata agaggccatc ttcttccgta atatgagggt agtctaaatc ttttagtgat
    50701 tggctgatcc gatgtgctcg catatattct agtgtccaat ctcctgccat tacttttggg
    50761 aagttttcat cactatgatg gcggaaccgg atatatagtg gatgcatatc tgcatctgaa
    50821 acaagcggaa cgactctttt gaccgcgttt cgaaatggct gctgctgatc atacatcgta
    50881 tcatcaacat caaacacaac tgatttaatc aaaattttac acgcctttcg gttttcattg
    50941 attttttcac aaatccttga ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat
    51001 aaaggttttt cttactatat ttctatttcc ttgacagaat aaggttttta tatttcagtt
    51061 tttttcacta aaaatcgtga aacacgtcaa taagtttgat gaacaaatta atcattatgg
    51121 tagaagtcga ttgatttatt ttaatgcaat ctctgtggaa ttttcgaaag atttattttt
    51181 ttaatacagt ctcaatataa ctattcaaac ataaaataac gttatttgat ttatttgttt
    51241 atagtaaatt ttatttagta atcattgctt taaaatacta cgcttatata acagagaaaa
    51301 taagcgttat aataaagaac agtattattt aaaatgacag aaaacattac tattaaagaa
    51361 ataaaaaaca taaaaaatct taagaaatcg gtttcattta gcttttgaga taaaataata
    51421 gtacagtttt atacgctgtt tcatatgttt agaaaatttg aattagattt gaaaactcta
    51481 atttttaaat gataaaaaaa gcgagaatgc tggttttact gtatattaac cttagataac
    51541 tttcattttt ttaaaaaaat tatgaaaaaa aggtagctat ttaaaagttg attatgtata
    51601 atagaaacag atgggagatt attatgatct tctgttacaa aaaagtgatt cttatcacga
    51661 aaaggagtgg tgcacgttgt taacattata tacttcccca agttgtactt cctgcagaaa
    51721 ggctcgtgcg tggttgcaag aacatcagat tccatttgtt gaacgtaata ttttttcaga
    51781 accattgaac agttctgaat taaaagcgat tttacaaatg acagaagacg gaacagaaga
    51841 aatcatctcg acacgttcca aagtattcca aaaactgaac atggatttag atgatctgcc
    51901 gttacaagaa ttattggaac ttgtgcaaaa caatcctgga ttgcttcgcc gtccaatcat
    51961 gattgatgat aaacgtctgc aagttggttt taatgaagat gaaattcgtc ggttcctacc
    52021 gcgcgatgta cgacaattag aattacgtca agcacaattg atggctggat tatagaagga
    52081 taatacgaaa cttggaaaag actattacaa agatagtttt tccaagtttt tttgttttta
    52141 caaaaagtat tcttgattag atgtataaaa aggtagtaga agatgatgat tgcacgaaaa
    52201 atagagaggg aaaattagct gaaaagtcgg ctatatagta ttcgtctgcc aaaaatgtta
    52261 tagttaaata agatagcttg aaaggttgaa aaatccgctg gttttattaa attcgcttaa
    52321 cagcgagatt ttttttcttt acatttaagc tgatttcgct acaatgaatc tatattaaac
    52381 attgtggcaa agtgaggtgt agcaaaatgg aaatggaaca tattaatgaa aatacgatcc
    52441 gtgtactaat tggtcataaa gatttagagg aacggggcgt ttcatttttg gatttacttg
    52501 gcaatcacaa agaaatcgaa aatttctttt atagtatttt ggaagaagtt gatatcgaag
    52561 aggagttccg aggaagcgaa gctgtcactt tccaagtttt gccaaaagga gacggattag
    52621 aactgtttat cagtaaaaat cttccggatg aagaaatttc tcaatcagaa gattctactg
    52681 ttgattcaga agatgtgagt gactttcttc gtcagcagat tattggcagc gatccggagg
    52741 aagaattatc tggaagcgcc ctagaagaac aggaaagaca agcaactttt gcttttgaag
    52801 attttgaaca agtgatccaa cttgcaacag atgtcgaact agagtctgct tggactgatt
    52861 tgtatttatt cgaagagcgc tattacctag tcgttcactt ctggatggaa aatctcaacc
    52921 aagcggatgt agagaatcag attgctcgaa ttttggagtt tgctgaaaag agcgatcgta
    52981 caccagaaac attgaatgaa tatggacaat gtctgatggc gcgtaatgct atcgagcgaa
    53041 cgaaatttta ttttgtataa atcagcatta tagtaagaga ctgtgacaaa aattgtgtcg
    53101 cagtcttttt ttcgtataaa tgtgttcaaa agcttgcatc tgcggtaaca agcccaacca
    53161 aacgaaaaat attgggaact atttttgttt agctgttctt attacttgat gcagaatagc
    53221 tttttcacgc cctctttttt cgtgtaaata aattcttaga cgtaaataag ttcagaggga
    53281 gaaaaatgct gcttgcaatg aatgaatata ataagtgctg ttttgctaaa catgcagaaa
    53341 aaggaaagaa atattattgt cgtggctgtc gaaaaagagt gattttgaaa aagggaaaga
    53401 aaaaatgtgc tcattttgcc catcaaaaat cagataactg ttcggtcttt agtgaaagag
    53461 aatcaaaaga gcacttacag ttaaaggaat gcttcatgga ttggctggga cagtcagtag
    53521 aaccagtatt tttggaagcc tatttgccga ggttgcggca aaggccggat attttgttgg
    53581 cgaatctagc aatagaaatc caatgttcta gactgtctca ccagagattt attgaaagaa
    53641 cccaaaatta tttgaataac agttaccaag tatggtggat acttggtaat tcttttcttg
    53701 gacaatcgca attctcattg atagaaaaaa gttgctgcta ctataataga aaaagaggag
    53761 tgcattgctg gaaagctgat ctcaagaaac aaaagcttta tttgtatcat catattacag
    53821 agactgtatc agggcatatt tccttttgca gtagctgctg gactttttct agtagggacc
    53881 ttaaagaaat attcactagt aacgaaatta aaatgaacca aatgaaaaaa atagaaaaag
    53941 tgagtgaaga tgggaagaaa tggctgacac gccaacttat tcacaagcaa aagaatacag
    54001 tatccataca agaacaatgc tacttgcgtc ataaacatct tttgcatcta tcatcgtgga
    54061 tctatcaaaa aagtcggttt ttcttttatt tacaagaaca ggtttttctt tatcgaatgt
    54121 tgtacgaaga agccttggaa aaccagaaag ttcctgattt caactcatgg ctttgccaaa
    54181 taaaagaaca taaaagggaa tggctttttc ctatgattga tgaagagatg gtctatcagc
    54241 agttttttaa cgaatgcata cacttgtctt ctttgaaaaa atagtaagta taaaaatagg
    54301 ctaggaatcg gttttctatg taaaacaaga tttagttatg ctaaaattga tggaagcaga
    54361 cacatgaatg agtagaaaag ttagatgctg tgacatgtgg atgttagact atgatctatt
    54421 ttgatagata gagctaaggg aagaaaagga gtggatttca tggaagtaaa gcagttgcca
    54481 aaacgagaag aattgcctga aaatttaact tgggacttga ccaagatctt ttcaagcgac
    54541 caagagtttg atgagaaata tttggaatta tcagaagagt taaaacaatc tgaaaaacac
    54601 aaaggaacac ttgatcaagg cgcttctcaa tttttaaatg cgattgaatt cgtattgagg
    54661 gtttatcgcc aaactgaagt catttatgta tatgcgcacc ttaaaaacga tcaagacact
    54721 ggaaatacag attaccaagc gctttatgca agagcaagca gtctgttttc gaaagttagt
    54781 gaagccgttt cctggtttga accagaaata ttgcaattgt cagatgacca gatttggcaa
    54841 tatttcaaag aagaaccaaa attggaagtc tatcgccatt atatccagca aatagtagat
    54901 aatcgagccc atgtcttatc tgctgagcag gaatctcttc ttgctggagc aggtgaaatc
    54961 tttgatgctt caagtgatac atttgctgtt ttgaataatg cagatctagt ttttccaacg
    55021 attgaaggag aaaatggtga aatagtccaa ttatctcatg gcgtgtatgg tcagttgcta
    55081 gaaagcacgg atcgaagggt gcgcgaagca gcatttaagg ggttgtacag tgtttacgaa
    55141 caatttagaa atacatttgc ttctacttta ggcacacata taaaaggaca taattttaaa
    55201 gcgaaagtcc gtaattacag ctctgccaga gaagcgtctt tgagcaataa tcatattcct
    55261 gaaagtgtat acgatacttt ggtagacgtg gtaaacaagc atttgccttt gttacatcga
    55321 tacatggaat tacggaaacg tttattagaa gtggaaaaac tgcacatgta tgatctttat
    55381 acaccggtct taggggaagc tccaattacc tttacgtacg aagaagcaaa agaaaaagct
    55441 ttagaagcac tgaaaccaat gggtgaagaa tacatggcca tcgtagaaaa agcattctct
    55501 gaacgttgga tcgatgttgt cgaaaataaa gggaaacgaa gcggtgctta ttcttcggga
    55561 agctatgaca caaatccata tattttattg aattggcatg atacgctgga tcagctattt
    55621 acgcttgtcc acgaaatggg acatagtgtt catagttatt tcactcgttc gaaccagcct
    55681 tatgtgtacg gcgactactc catcttttta gcagaaattg cttcgacaac gaatgaaaat
    55741 atcctaacgg agtatttatt ggaaacagaa aaagaccctc gtgtacgggc ttatgtactc
    55801 aaccattact tggatgggtt taaaggaaca gttttccgcc agacacaatt cgctgaattc
    55861 gagcatttca tgcatacgga agatgaaaaa ggtgtgccat tgactagtga atacctaagt
    55921 gatagttatg gtaaattgaa tgcaaaatat tatggtccag cagtcgaaga agacccagaa
    55981 attaaattcg aatggtcacg gataccgcat ttttattata attactatgt tttccaatac
    56041 tcgactggct tttctgctgc ttcagcactg gcgaagaaaa tactaaacca ggaaccagag
    56101 gcactagaga actacttggc ttacctaaaa gcaggtaaca gcgattatcc tgtggaagta
    56161 atgaaaaaag caggagttga tatgacacag gctgcatata ttgaagatgc aatgtcgatg
    56221 tttgaacaac gtctaaatga attagaagaa ttgatcgatc gtttataagg ctttctattt
    56281 ttgattttct cgaatagaaa cgaaaaaaat acgtcggctc tcttgtaagg gagtcgacgt
    56341 attttttta
//
LOCUS       DAPBCF010000014        55372 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.014, whole genome shotgun sequence.
ACCESSION   DAPBCF010000014 DAPBCF010000000
VERSION     DAPBCF010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 55372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.014"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..1058)
                     /locus_tag="RD508_001026"
     CDS             complement(<1..1058)
                     /locus_tag="RD508_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDT7735637.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTIS"
     gene            1331..3802
                     /locus_tag="RD508_001027"
     CDS             1331..3802
                     /locus_tag="RD508_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7735638.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3905..5641)
                     /locus_tag="RD508_001028"
     CDS             complement(3905..5641)
                     /locus_tag="RD508_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDT7735639.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(5638..6342)
                     /locus_tag="RD508_001029"
     CDS             complement(5638..6342)
                     /locus_tag="RD508_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7735640.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            6473..6976
                     /locus_tag="RD508_001030"
     CDS             6473..6976
                     /locus_tag="RD508_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDT7735641.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6936..7274
                     /locus_tag="RD508_001031"
     CDS             6936..7274
                     /locus_tag="RD508_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HDT7735642.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            7295..8713
                     /gene="ffh"
                     /locus_tag="RD508_001032"
     CDS             7295..8713
                     /gene="ffh"
                     /locus_tag="RD508_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDT7735643.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8825..9403
                     /locus_tag="RD508_001033"
     CDS             8825..9403
                     /locus_tag="RD508_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HDT7735644.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            9407..9928
                     /locus_tag="RD508_001034"
     CDS             9407..9928
                     /locus_tag="RD508_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDT7735645.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(10007..10561)
                     /locus_tag="RD508_001035"
     CDS             complement(10007..10561)
                     /locus_tag="RD508_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDT7735646.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10814..11089
                     /gene="rpsP"
                     /locus_tag="RD508_001036"
     CDS             10814..11089
                     /gene="rpsP"
                     /locus_tag="RD508_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDT7735647.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            11101..11352
                     /locus_tag="RD508_001037"
     CDS             11101..11352
                     /locus_tag="RD508_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HDT7735648.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            11477..12268
                     /locus_tag="RD508_001038"
     CDS             11477..12268
                     /locus_tag="RD508_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735649.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            12438..12959
                     /gene="rimM"
                     /locus_tag="RD508_001039"
     CDS             12438..12959
                     /gene="rimM"
                     /locus_tag="RD508_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HDT7735650.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12949..13710
                     /gene="trmD"
                     /locus_tag="RD508_001040"
     CDS             12949..13710
                     /gene="trmD"
                     /locus_tag="RD508_001040"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDT7735651.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13846..14193
                     /gene="rplS"
                     /locus_tag="RD508_001041"
     CDS             13846..14193
                     /gene="rplS"
                     /locus_tag="RD508_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDT7735652.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(14325..15461)
                     /locus_tag="RD508_001042"
     CDS             complement(14325..15461)
                     /locus_tag="RD508_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7735653.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLQKPNLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKMPETYIVSGINTVDLNNIFEDMIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKN
                     PINEVVIDYKRESKTIKIKDKFLEDDEYKRLVDFTTSHNKRYSLLFQWLYLTGMRPGE
                     AIALSKDDVHITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAI
                     YNELLELNPKGQFLFQTTKGTPFQLTAINTYLRNHKADMKIDKKLSSHIFRHTHISKL
                     AELGTPLYAIQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
     gene            complement(15578..16270)
                     /locus_tag="RD508_001043"
     CDS             complement(15578..16270)
                     /locus_tag="RD508_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735654.1"
                     /translation="MKKVILGLVFGAFFLTGCSQSNVVDNTGKTNEKDSSVTLSESTT
                     QSSKNSQEVDGPLLKVGQWTKEKRDTSGKIELIGTASPQSDIPLGDIGIYISNIKLLK
                     YSNYADPSAAGYYDANNHKDSEGNFYGLQIAFKVKNNSEVDYGYNGLAHAILDNGQQI
                     DFSSDDLMHTMTTNSFFKKTESKEFYSLAYLDPSKVNDITKVTIKTGVLYNPSDYSTV
                     AESAESTFNINR"
     gene            complement(16408..17061)
                     /locus_tag="RD508_001044"
     CDS             complement(16408..17061)
                     /locus_tag="RD508_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735655.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDATSNQETKVSKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQATAEPSPTVISSSQDTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     GQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFSKYGIQ"
     gene            complement(17111..17539)
                     /locus_tag="RD508_001045"
     CDS             complement(17111..17539)
                     /locus_tag="RD508_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDT7735656.1"
                     /translation="MEMDTINLVEELKRKYRSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRGRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKKIDELKNLYGLPESAYRFLI"
     gene            complement(17544..17918)
                     /locus_tag="RD508_001046"
     CDS             complement(17544..17918)
                     /locus_tag="RD508_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7735657.1"
                     /translation="MNLLDRIKELAHKRGISITQLEEELNIPKNTIYQWKNRTPSTKR
                     LQLVADYFNVTTDYLLGRNQVPDWATKDEVVELDKLLDSNVNMSYGGETLTPEQVQRV
                     KDILIGTFWDIVKEDKEKGKKM"
     gene            18203..18388
                     /locus_tag="RD508_001047"
     CDS             18203..18388
                     /locus_tag="RD508_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7735658.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALVGISGAYLSDILNGNRDG
                     KKAQQHIETVKKILDIR"
     gene            18401..18649
                     /locus_tag="RD508_001048"
     CDS             18401..18649
                     /locus_tag="RD508_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735659.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKITPKEFIEKHLVDL"
     gene            18680..18850
                     /locus_tag="RD508_001049"
     CDS             18680..18850
                     /locus_tag="RD508_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735660.1"
                     /translation="MGKFNRALVFSTPFIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYKTKKPVGRD"
     gene            complement(18948..19613)
                     /locus_tag="RD508_001050"
     CDS             complement(18948..19613)
                     /locus_tag="RD508_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735661.1"
                     /translation="MSLIDFIKQFDWNNIVKTIKDFILPITSLVFSTFAFYISYTDRK
                     NKKFNLKLDFFAECEEWLIDRESDSKPDVYHQNKFRIIDSVLLTNNSSLPVTIIEFSI
                     SGIPDHLNAFTMIGDNYSVTVKSMYDELPHGIRAYSGKSLKKGADLSKFPPLSLPITI
                     PPYESKITTLVFRYDESLVEKNITINVLTSRGTAKFNRFVSSSQISQLDTGYAPPQLD
                     EFD"
     gene            19668..20366
                     /locus_tag="RD508_001051"
     CDS             19668..20366
                     /locus_tag="RD508_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HDT7735662.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFSEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLKEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNIKVMEVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDENE"
     gene            20544..20885
                     /locus_tag="RD508_001052"
     CDS             20544..20885
                     /locus_tag="RD508_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735663.1"
                     /translation="MEKELSTLDQYLTDPSWGKSNIKETNNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKPEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            20878..21549
                     /locus_tag="RD508_001053"
     CDS             20878..21549
                     /locus_tag="RD508_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HDT7735664.1"
                     /translation="MSENKGTTTFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            21555..22241
                     /locus_tag="RD508_001054"
     CDS             21555..22241
                     /locus_tag="RD508_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735665.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYVLIGDIFIDTGMPTDFWKEFFYFRFEGVTGREISLK
                     DESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVTNFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            22244..22471
                     /locus_tag="RD508_001055"
     CDS             22244..22471
                     /locus_tag="RD508_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735666.1"
                     /translation="MINLNAVAFEQTWRTKYKKMSPRDKLFLEIMTFAFIGTQAEQSD
                     ISVEKIKTNRLVNGITETCYQYTIIVVDEEE"
     gene            22474..23301
                     /locus_tag="RD508_001056"
     CDS             22474..23301
                     /locus_tag="RD508_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replisome organizer"
                     /protein_id="HDT7735667.1"
                     /translation="MAERRMFAKTIIDSDAFLDMPLSTQALYFHLSMRADDDGFINNP
                     KKIQRMVGCGDDDLKLLMAKRFILVFESGVIVIKHWKIHNYIRNDRYKPTLYQDEKAL
                     LADKDNKAYTFAEELSKHDEKLGIPDDNQAVYQMDTQVRLGKDRLGKDSKEIKDLTPS
                     KKSKAKPIRHKYGEYKNVLLSDEQMEKLKTEFPNDYQERIERLSEYCESSGKTYKNYL
                     ATIRSWARKEKSESKNASSGYKRTGRREKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            23313..23582
                     /locus_tag="RD508_001057"
     CDS             23313..23582
                     /locus_tag="RD508_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735668.1"
                     /translation="MKIDYLELINEIANYKTGEEIDILRDVYDQLEEAGIEGINNDRS
                     SWSKLRYYFALYIDATQLRNLAYTKLLFVDCIKGLQKHLSELEQV"
     gene            23587..23751
                     /locus_tag="RD508_001058"
     CDS             23587..23751
                     /locus_tag="RD508_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735669.1"
                     /translation="MDLKTFTAQIELMHQEALRQSASYEDKWLNTFHGGRESALDQVL
                     KLLKGERRDG"
     gene            23744..24046
                     /locus_tag="RD508_001059"
     CDS             23744..24046
                     /locus_tag="RD508_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735670.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVTEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEKK"
     gene            24043..24354
                     /locus_tag="RD508_001060"
     CDS             24043..24354
                     /locus_tag="RD508_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDT7735671.1"
                     /translation="MNELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            24351..24569
                     /locus_tag="RD508_001061"
     CDS             24351..24569
                     /locus_tag="RD508_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HDT7735672.1"
                     /translation="MIGLTIFWCAIGGLLAFLGYYLICESRKGRKYTVTGIVLLIIGI
                     LVAVGAELNLYVNGTQEDLVRFMFWMKN"
     gene            24580..25395
                     /locus_tag="RD508_001062"
     CDS             24580..25395
                     /locus_tag="RD508_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HDT7735673.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            25534..25890
                     /locus_tag="RD508_001063"
     CDS             25534..25890
                     /locus_tag="RD508_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HDT7735674.1"
                     /translation="MDLITQYSDIILKKIMAKIQKDKKAKERAELVKLEMAETGVGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKAHSIQHGFI"
     gene            25877..26095
                     /locus_tag="RD508_001064"
     CDS             25877..26095
                     /locus_tag="RD508_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735675.1"
                     /translation="MDLYDIESGATVSVESDHLIISFADERQIIIWVVDDMLYPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSK"
     gene            26092..26490
                     /locus_tag="RD508_001065"
     CDS             26092..26490
                     /locus_tag="RD508_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HDT7735676.1"
                     /translation="MIPKFRAWDKRENTMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVEIFEGDVVITSKGAIGYVAYLQQEAGFVVVLKKSDYRLG
                     HRNTGESYDVATAHEVIGNIYENSELLEVE"
     gene            26487..26825
                     /locus_tag="RD508_001066"
     CDS             26487..26825
                     /locus_tag="RD508_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735677.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            26822..27052
                     /locus_tag="RD508_001067"
     CDS             26822..27052
                     /locus_tag="RD508_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735678.1"
                     /translation="MKYEIPLSEAGIQAIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSINDTFRLGS"
     gene            27059..27262
                     /locus_tag="RD508_001068"
     CDS             27059..27262
                     /locus_tag="RD508_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HDT7735679.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASETIRKFGISILNDDRKWEAER"
     gene            27259..27552
                     /locus_tag="RD508_001069"
     CDS             27259..27552
                     /locus_tag="RD508_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735680.1"
                     /translation="MKLKDGFYTDAYGIGGLMMDLPTKNPIKQEESEIKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKRLAKSKENLAVVRLVDMEVIKS"
     gene            27582..28022
                     /locus_tag="RD508_001070"
     CDS             27582..28022
                     /locus_tag="RD508_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7735681.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            28097..28564
                     /locus_tag="RD508_001071"
     CDS             28097..28564
                     /locus_tag="RD508_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HDT7735682.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQPR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            28841..29077
                     /locus_tag="RD508_001072"
     CDS             28841..29077
                     /locus_tag="RD508_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735683.1"
                     /translation="MYWRVYKMNNASEKIDQLTILVNQRIEDIIKEFEGEKIKSIKLT
                     LMDHKFELNSTKRKIVELIEKEIAVQINEQQLTN"
     gene            29101..29313
                     /locus_tag="RD508_001073"
     CDS             29101..29313
                     /locus_tag="RD508_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735684.1"
                     /translation="MDKESARELYLSKFKRNNKPEEVFGSNVKEVGEKLTQLLKEEDL
                     TYDEAYASLQYCYNLLKYESNFLKLQ"
     gene            complement(29291..29764)
                     /locus_tag="RD508_001074"
     CDS             complement(29291..29764)
                     /locus_tag="RD508_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735685.1"
                     /translation="MNLSEVQAAYFILNCLDPDNYTVKLYVKNGCKIFSADFLKLSET
                     GWSVIQESLDEDFDFSNPKISIASGAEKGFLWAKAAKTWNDSFSYPRQSVKLLDHPQL
                     LLEKIKAFIGNLQIEDYREFSTLAYNTEYIDGKKFNFCLLPESNYELFTIEVSEN"
     gene            29897..30112
                     /locus_tag="RD508_001075"
     CDS             29897..30112
                     /locus_tag="RD508_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735686.1"
                     /translation="MKTRETRAKRNHARFDSLPATLNAYDGYDYRKKIVKKLYGATYG
                     NVVSVLSVHHQASVTVAEVEDAAVNGE"
     gene            30304..30516
                     /locus_tag="RD508_001076"
     CDS             30304..30516
                     /locus_tag="RD508_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735687.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQSKYFYDQL
                     ILQGFNEGQAMEFMMRTFSASNQQKE"
     gene            30523..30750
                     /locus_tag="RD508_001077"
     CDS             30523..30750
                     /locus_tag="RD508_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735688.1"
                     /translation="MRNYWYISLTNEYPRTIDDCSVRVVRSVQIKKKYSIIEMTREAT
                     PNEIDKYNLRYCGHGYWKDEYIQQNIERYIK"
     gene            30747..31031
                     /locus_tag="RD508_001078"
     CDS             30747..31031
                     /locus_tag="RD508_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735689.1"
                     /translation="MNDNYDYIKLIEKIRAEKDMDELANLFMNIISLVGLKMDEVAAL
                     NYFIAEQTIRAEHNAKFLKDRLDLDVKGLGVEGIFKVQEALVNVYVEKMQ"
     gene            31072..31644
                     /locus_tag="RD508_001079"
     CDS             31072..31644
                     /locus_tag="RD508_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735690.1"
                     /translation="MKLKDYIREGYNIVTTPNLAYKIQEDYPNVLVFTDRALDAIPIG
                     KLLVDRYYSNNPAVLSAKPLQNAYAIERFTCEFTGYETVVPMTGETGRKVIQQIKKRI
                     AELTLDDGSNTNLLEIKLRDTDSVPEVYYKGQRMDEMPIGLVDITYHWHTEEYECQVP
                     KGANDITIEYYDSHNNKYLDRKIIGHKRDM"
     gene            31645..31956
                     /locus_tag="RD508_001080"
     CDS             31645..31956
                     /locus_tag="RD508_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDT7735691.1"
                     /translation="MIDVSTKQARARFYGSTEWRKLRSQCLERDHYECQWCKAEGRLT
                     TQHDSILEVDHIKELEYHPDLALDINNLRTLCKDCHNKRHNRMKYRGQQKKRKWDDEW
                     W"
     gene            31947..32207
                     /locus_tag="RD508_001081"
     CDS             31947..32207
                     /locus_tag="RD508_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735692.1"
                     /translation="MVVRKTANRDDVKRAEAIAMVDKAIDKLVLFKSQLIEETTTVED
                     ISINNRLIGNANEVTGTFNINVDIDYTLSPFAHIVESNEQDG"
     gene            32375..32929
                     /locus_tag="RD508_001082"
     CDS             32375..32929
                     /locus_tag="RD508_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016630802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7735693.1"
                     /translation="MIGLNSKLVGTRMKQKRIEKGLTQADVATKSGISSRYYGSIENG
                     KNSPSIETLNSISIVIGCSLHFLLNDRMDDMEKRVELEKKRLQKIFDKIPHDKLNLVE
                     GLIIQAARLRVLLDDNWKDIIENGEYEKFKQSENQIAYDRKRPIVENYDNRDKTYQAI
                     VKQLTDLLPQGTRADKKSKLLGRK"
     gene            32932..34623
                     /locus_tag="RD508_001083"
     CDS             32932..34623
                     /locus_tag="RD508_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDT7735694.1"
                     /translation="MLFNQHVDQYIRKWKSGELILNEKRIQLLKLIEKEILPRDDIYY
                     FDEEQINNYIEFSQAWYFELDEWEKFISAFIFLFYKEDDEVVFDEFVINMGRGGGKNG
                     FISTLANYFVSSLHGIDYYDVSIVANSEKQAKRSFQECYRVINKKGNEDLKEEFEAYK
                     SSLTGLETQSVFEYKTSNASSQDGGREGAVIYDEYHEMENTDIVDVFSGGLGKVDHGR
                     QFFIGTKGFVREGYFDIKYRECEDILNGLSEFKGVFPYICELDAIEEMDDPKNWPKAN
                     PALQPPLNKRGKRLFNEVMKKYKKLAKEPSGRSAFVTKRMNFLEDNMENSVASREEIM
                     ATNRPFFELDTVPIGSLDFGSVRDFATCGLLFKNRKKSEYAFKSFTFAMKNFCDVHYG
                     YSLKEQLVGSEKRAPIKTWEKMGLMKVIDEPSLNPKYIVDWFIQAREEYGVRVIVVDN
                     YKADILGPMLEKEGFEVVRLKRPSSLHPLLAPRIEDGFANHKFIFGDNPLMRWFTNNV
                     YVKETQAGKQFLKKEEVKRKTDGFQAFVHALYKATELDEQIDYDDAFDMLDEIEF"
     gene            34655..35602
                     /locus_tag="RD508_001084"
     CDS             34655..35602
                     /locus_tag="RD508_001084"
                     /inference="COORDINATES: protein motif:HMM:NF028182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735695.1"
                     /translation="MRIKGKNISWVFYMLGILAFTFVAIKLSEIIIPNDSVVSKNLVL
                     ERAKLIISILGPALTLIVFVRTIQTQLESSKNLIKDNVSKDFYNLLNLFKSIQDKMNS
                     ELFSTIEKRIKVPINNINTNLDVRENKETTKEVQEDLKEYSASLNKVLSESVKKINEI
                     FEDNYKDIGSYLKVFHRILKILNNRYESKDISHEEYKMYVGILRSQIEDYEFYIILIN
                     SLFTLRGTGMGIELIETSFFGDELDIDLKQHFEHPEFLTEIIKDNFVEKKSYRESVKT
                     RKKNRKLFENRKINDNLLSLLRIRYTLQDGNKIIISNGV"
     gene            35651..36823
                     /locus_tag="RD508_001085"
     CDS             35651..36823
                     /locus_tag="RD508_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDT7735696.1"
                     /translation="MSLFDIFKQSIKNEDPSDWIPDFVFGDEESARAYLKIMAKSTVL
                     DFVARTMSTLEVKFKNKDGTSDWDYILNVRPNSDMSAATFWQKFFYRLLDDNEVLVIF
                     TDDNQLLIADDFSRTEYAVYDDVFTNVMVKNFVFERSWAMSDVIYMEYNNEELERFTR
                     GLFEDYAELFGRILEVAMRNNQIRGSVSIDSTGTANDEKGKDGKTRSQRLQEYIDKIW
                     NSFKTNSVAIVPKVKGFEYEEYTNKQGVSNQSLDELNKMKSSLIADVANAIGVPTALI
                     YGEKAELDSNIKAFRKLCIAPLVKKLQDELVAKIISRQEYKNGERIEVKKVLQKDLLE
                     YATQIDKITSGGAFYIDEVRDEVDYDELPNNEGKIRIRTKNYEETVKGGENDNAES"
     gene            36810..37514
                     /locus_tag="RD508_001086"
     CDS             36810..37514
                     /locus_tag="RD508_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HDT7735697.1"
                     /translation="MPKAKKVPFQFTNEIQNGKHILTLSGNVQKKYWRDDDVINAKDI
                     RDSLDTVTDDIVIKLNSPGGDVFEGIEIYNYLKDHPSNITVEVTGLAASAATFIVAGA
                     NDVIMNVGTSLMIHEASTFAWGNKQDIQKTLNALETIDDSILAIYSDKTGQSVDKLRE
                     WMNEEKWFTADEAVKYGFANSVKREEPQNEPQNIAAMIQDAVAVAIANLKEPVTNKIE
                     QESKQKSLIARLRKGE"
     gene            37519..38679
                     /locus_tag="RD508_001087"
     CDS             37519..38679
                     /locus_tag="RD508_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDT7735698.1"
                     /translation="MLKITDKTADAKKAFNAISSKEDATPEQINAALEEYVTAIAEDA
                     GKQVRAEYEELKNVTDNRVLEARGIPTLTVEETKFYNEAVKSGGFDSDVVWPETILER
                     VFENLQNDHPILGLINFTPTVGRVKVIRARRKGVAVFGPLHKDLEGQLDAEFGATEFV
                     QLALTAFFLISNDTLDLGPRWIDRFINLSLSEAVRDVWAKKIITGSGKDEPIGLLKDL
                     DGAVTSGVYPDKASAGTLTFAKEKIVLELAGVMKKLSKYTYKVDGDDEGEVEYRSVAG
                     RVYLIVNPVDYWDIVARVTFANLNNVYGTTMPFIAVDHIIESVDVPESKCIAYVDKEY
                     EATQSRAEKVYVYKETFAMKRATLYAVDMLGNGYPTNNDAAQVYDLDFTAGE"
     gene            38755..39033
                     /locus_tag="RD508_001088"
     CDS             38755..39033
                     /locus_tag="RD508_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HDT7735699.1"
                     /translation="MNTEEFIKEYKARFRIFHTSEDEDIGKQLESGFADIKSLIGSFD
                     PSTYEKGKELVYERTRYLRNESLEYFYDNFQTMIMDASIDLAGAGYAN"
     gene            39014..39385
                     /locus_tag="RD508_001089"
     CDS             39014..39385
                     /locus_tag="RD508_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HDT7735700.1"
                     /translation="MLDMPIKSNYKKPKIVAGDLNTPVTFFEFQPNKGPEPGDEEKKE
                     LYFCTALVYNPSMKDRDILGTKEGVTIKIRDPHQSYIPTNKHKVRILDYRYGDKVWEI
                     IDVSPDLEENSIVKIVLELIT"
     gene            39401..39805
                     /locus_tag="RD508_001090"
     CDS             39401..39805
                     /locus_tag="RD508_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735701.1"
                     /translation="MSNVKFEGVQETIQALEKKFGEKKTKTLTKKAINVGAEKVEKQL
                     QTDMTVFKDKGYTIDEVVRKNATYRNYKAEAEIGWNGPHQRYRIIHLNEWGYTRKGKQ
                     IRPRGFGVITKSLKNSEPLYFDAVGEEVKKRL"
     gene            39802..40212
                     /locus_tag="RD508_001091"
     CDS             39802..40212
                     /locus_tag="RD508_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735702.1"
                     /translation="MKDMLNIIYEALCLNEYIRSMTYNENTEQYRIKFYEQPETADKT
                     GPMITLRPVDTPNEAYHGSNKELSVEHMVQIDVESKYRATCKQIQYEIKKEMKKLGFG
                     QISGQGLDEYFSETKRFVDARRYEGNTKIYDTEY"
     gene            40273..40860
                     /locus_tag="RD508_001092"
     CDS             40273..40860
                     /locus_tag="RD508_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7735703.1"
                     /translation="MTLVGFKKMTIGIFDSTGKIPAANLYVIEGEQDKGATVSAEISG
                     LSKEPSKVYGSNIAYYVSQKGTGDVSATFGLLDLPTEVNDKILGYKTDTNKISFLGED
                     TEPPYCAILMESEDLNGDTAMLAMFKGKFSRESINLNTTTNEAFEPEAEEYVFSAIAN
                     DVEGDAKGQTVAKYVGDEEASITALKEMVFPAAGE"
     gene            40933..41400
                     /locus_tag="RD508_001093"
     CDS             40933..41400
                     /locus_tag="RD508_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig domain-containing protein"
                     /protein_id="HDT7735704.1"
                     /translation="MPDTFKIYKKNGTEFTKVAEGESPLSITGIAANTQVAKGDYQAT
                     RVVGGQESVKVDIPAFTTLPISVTGVTLDKTTAEVEQGGTLKLTPTVTPANATDKTGS
                     WSSSNTAVATVTGGNVTVKTDAEVGGTTEVSFTTTDGGKVAKCTITVIEKAAG"
     gene            41446..41754
                     /locus_tag="RD508_001094"
     CDS             41446..41754
                     /locus_tag="RD508_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735705.1"
                     /translation="MAKVRIELKEESGKKVYENIDTTGKDYRKALETIKKLNEDGVMI
                     WNRLDIYLDFAVGIFRDSKLTAEQILDGLPSEKVMSTLDDILGEVMGIESNPDPDAKK
                     "
     gene            41949..48713
                     /locus_tag="RD508_001095"
     CDS             41949..48713
                     /locus_tag="RD508_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDT7735706.1"
                     /translation="MANGKPLGNMIIKLDLDSSAFSKGLAGAKNAVNHQMKAMKSQMQ
                     VMNSSGNSLGALQAKYNGLGGVLQANEKQVELLTKAYKDSFDSNGNATASTAKYANQL
                     NQATARSASYESQMKTTVGQIARMKVETEGITGKLKANSDVLINSGKKIEAFGKGVSG
                     IGSALTVGVTAPIVAGATAVTSAAISWESAFAGVKKTNDEVVDSNGNVVYSYSDLEKG
                     LRDLATKLPASHQEIANVAEAAGQLGIKTENVVSFTKTMIDMGESTNMSAETAATSLA
                     RFANITQMSQKDFDKLGSVIVDLGNNFATTESEITEMGLRLAGAGKQIGMSQGEILGF
                     ATALSSVGVEAEAGGSAFSKVMIQMQLAVEKGFGAFDQLKQMAEEQGVPWVNLVNAVR
                     DGGKSLKAVSEQMGFTSSDLKKMYKEADNSKSSLENFANVAGVTSEQFQKLFKSDPSE
                     AIIKFIQGLKDSEKHGTSAIKVLDDMDIKEVRLRDSLLRAANASDIFKGAIEKGNGAW
                     KQNTALTNEANKRYETTESKLKMLKNEVIDTAIDLGGPFVDALRDGLNVSKPLIKNLG
                     NMAKAFSAMSDDQQRNIIKWVGLAAAAGPALKLLGTGTSVIGKVTSTTGRLTKSLVDL
                     AAKAAEKKALDAFASSVTTAGAAAAKTAGAGGIGGLVPMMGKTASAASTAAGASGIGA
                     MTTSLGLLGPALLGIVGVGGALAVGYGAWKLFGEEAWNSSQRVKQWGTDVGEEIDNTL
                     DGVQKNIEGANGQFGLLKEGFTVDDANNMAANFATAGTSLETSLTGRIKALDDALKGL
                     PQSVQDAMKEVAESEEETLGQSLSKIKDNNEEIKKIRERAANQNRDLTVSELQQIQDL
                     MKGTSQAYVDTLDVSAKDRKKILSAMNGDVAQATEEEAKTWLQSLAKQKAATTENYRQ
                     MLEEKKAALKEKGVSKEFIDALEDEMNDYIKTTNQGFDSQIAAITNKYPQLINEVSLS
                     NGQLFSKTAAAMDNTGQYTKVFLESNEKILAQAKKTSDEIADNAEKNAEQLGMVADEA
                     THAGSTWNGLVLDEKTGKVKTNVQEVVNEATKDFTKWNELKPVVHDAKLTTNAKDVIS
                     IAAVQNGYWDDMEWKEKEALLEDECSKNVYKALENAGKWNELDIPSKEAILTSNTPEV
                     MGETLMNLGLWDTYKLQVKDLDLNAYKVYDAIDGSEEKLNSWAQLDNPTKELLLDNSD
                     FSTKLFNSEEMFKRWNQLSSNAKFLSANNTKFTEVLLSSDRMWNQWVNLPDNEKRLLA
                     DNEDLATTVLSSEEIYGRWTQLPDNQKYMLADNTDLANKIFASEESWNAWKAIPDIVK
                     NLLGNNIDLLAKVKDGTVSVEEYNKVMPLLKTLYGDNVNLKEAISGAKSSIENYNKNI
                     FPNDKTAVGHDEASQAAKDAFEAFNIFQTKIPDKITKTVSADFIGPMPNAKGTNFHPG
                     GAAMVNDQKGPTYEELITLPSGEAFIPKGRNVVLDLPRGSKVLNATKTKRLVPKYADG
                     IGNITTVSSTLNLDALILAINELTTVLRTQLMAETTNAKDTKLSDETKVADPIIPGSL
                     SEKSDQYLGIGAQWLTNLMNGWNSAVPQYMNSEMVFITNYLNALKLQNNPNYTQGVAW
                     NKNLLNGWNSLTGTFISTINSFCNQAMVTLRNYNTPMYNNGRTWQQNNLNGWNSLYGS
                     FIARVNQLGNDSINNLRSKSGGFYNAGTFLLQSLINGMNSLGNSLSTTMNNVANTMVG
                     GMGKGVNGVISGVNYVLKEVESSKNIGNWPIPQYAKGTDGHPGGLAMINDQKGLVHEE
                     YVQMPDGRGFIAKGRDLLVNLPKGAQVLNASLTKKLKERLNIPHYEKGIGNLDIVDLL
                     DDEKRMLEFLTSKVDFSGINEPWLDMTKSGTSLMSKAANTMLQSKLSEFFTHGNFDGA
                     VNANGVYQYLVDVAQKVMGKFPGLTVTSGYRAGDAYYHGKRQAIDLAYPGISGDPRYT
                     AAANYAFEKFPSKIAYVITNGRVRDRMGLSGTGSSGQWTNWPDGDHFDHIHLNGSMGS
                     GDIFNGGVGGSGVARWRSYVSKALKMNGLPATAAYINAWMSQIQTESGGNEKAIGGND
                     GLAEGNATGLLQTKPGTFAANAFPGHGNIMNGFDNMLAAINYAKKRYGVAGMLQVIGK
                     GHGYANGGLITKDGLYRAGEGNKPEMVIPLTRKTRAIELMGQALAFLSGDDKKRSNTT
                     NTADNSAELVTLIKQQQKQHNELMMILRAILGKDLSLKSSDIGQAANHYMGSDLNKLR
                     YTNGGV"
     gene            48717..49538
                     /locus_tag="RD508_001096"
     CDS             48717..49538
                     /locus_tag="RD508_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HDT7735707.1"
                     /translation="MFYKLQFNQNGKLFDPQRKEKIVCKEIKRQAPVYEVNYEDFEGT
                     NGSREANASFRPFELVLTFDIFYKNKHDKELLLTEFYELIFVGYQYYISYDLSPGKRF
                     KVNPTNFEITEEENDYSTIEITFSIPSGSAESSATTLTDFNLEEEWQFSQGLVAEDYK
                     YTHQTSHFIIYNAGSFEIDPREHYLRIALEGESEGNVTIFNKTTGDRFIYYPSLSTNL
                     GQTLVLDGVIPKLNGVSCGINTNHGLINLVEGVNEIEIQNITRVKSSWDFRFLYK"
     gene            49547..50590
                     /locus_tag="RD508_001097"
     CDS             49547..50590
                     /locus_tag="RD508_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7735708.1"
                     /translation="MTELIIRNYEQTKEEILVGYDKGSFYENWQQNETWEIGFTVTSN
                     SLNQEVFDLVEYESSVFYNGQEFVIKEMTRKALGQLLTKQVVATHIYYTVQDGYQYNT
                     VTGAKSISQLLTHVFSAGSRGFTWEVIDPNKKFLTVEQENFGNANYLKLINEILSDYN
                     AVVIPNNKHLTFYPASEYGQQTEEQIRYKYNTDEVSFDIDTYSLKTQIKGYGKLKDGA
                     NTENPKDSDYIFTPITYTSPESQKWGIRIQDPVKDERYTVSGNMLERLKTDLQDYPNI
                     SGSVTLKWKISPNKGDHVPFIYEPLNINTYIQVVGIKTYPAIPNKPPEITLSNTKKTM
                     TSILAEMAKKGVI"
     gene            50590..51621
                     /locus_tag="RD508_001098"
     CDS             50590..51621
                     /locus_tag="RD508_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735709.1"
                     /translation="MGLLKLISNRISTEWKEKFNKNIDYLNDLEKKLSDQDKSMNSRI
                     DNLVLHSGGESPNEVVDARVNNKGETFPTLHGRLVEHETLTDEQISELNTNMDSQKEQ
                     VQQLNKSVQQIIGGYNEPINIYVSKDGSDILGDGSEEKPFLTIQTAVNNVPLITTSQI
                     TIWVGSGAYLEDIMIRNLNFTSFLIRPIDNFDTIDPLKSDLPVKIRSICFTACKGYCQ
                     VAGMQIVDTANGADYGIRNEQSGYMAINRCKFAENTKTLARYNAVYVGGTSKINMYGD
                     TTLINQKVAIYAVLMGEIFVSAFGSGNDVGILCENGTVRGTVSTSFATTPTKTTGYGL
                     IITKGTVLQ"
     gene            51621..53723
                     /locus_tag="RD508_001099"
     CDS             51621..53723
                     /locus_tag="RD508_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HDT7735710.1"
                     /translation="MVYKTNESIIMIQAEATSPNRTNVVFWSHDRGTAKLRMKLVRKN
                     GIPQSLPEGTTVPIRLMLKSATAEGGYGKHDYLATIEDRVNGIVSIVLEDNILGYVGI
                     VEGSVYIDFPNDRSLDTAGRFTFDIKRSPIDDSTPELEDYYFNGFSQTIDKIEKILAD
                     GKQEIEQKITESETQIDGKLKETSNKITKANQDVATINTNIDKANDRIDQTNQQISDL
                     GKLKKMYSNSIDFGNYDYSGNPNLMANINADSFSQGSGALSVVDDGDEVVITLDPNHK
                     LEIFKAKSQPALVVGKTYTMSVEIMLEDDFTGDPSNISLRYIKMPSWLTVLYTPYTLT
                     NTKGVWQKLTVTAKMTTAIDNAESWFIMLQNKDANNSLSGKLRLRHAKLEEGSTATPF
                     QPNLLAEPYNMCREYPNENIADPKVKFPIESGDHQIYQGYTEEELMIGQTYTITLKGT
                     KPASQTFVAYNHWTARLGELKPVDGLTDVWSLTFTPTNVVAMPKLFRVYQYPRSTVGA
                     CQIDWLKIEKGNTRTPNISQFKYFGEGLKDSNNPNDYSWDVTPEYTEKGLNNAVNVYD
                     PQRVEGLKNFADGIQIAGDKVISENDCTVYTLTKDNSQSFIDGYATFIKHGKEVVVNG
                     TVKFKKAYAFGVPLDDEVPDEFIARIVHGMLTGQSGTNSVSKAMYVQKDLGKIMTNSE
                     FAANEWFTFHGNYWVGVK"
     gene            53724..54170
                     /locus_tag="RD508_001100"
     CDS             53724..54170
                     /locus_tag="RD508_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735711.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGLRADGEPL
                     TIADQMFDPKLNQWIVLANTLDHNDLNNLKAMYEALEHENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPTLKGGE"
     gene            54172..54309
                     /locus_tag="RD508_001101"
     CDS             54172..54309
                     /locus_tag="RD508_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HDT7735712.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADKIISKEESA
                     S"
     gene            54344..54586
                     /locus_tag="RD508_001102"
     CDS             54344..54586
                     /locus_tag="RD508_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HDT7735713.1"
                     /translation="MKEEALQDVVERLVRIETKLDNYESLREKADSAKDLADKAYSVA
                     LNNAEDIKEMKNNNKWAWGYMIGLGITIIGYFLTKL"
     gene            54602..54799
                     /locus_tag="RD508_001103"
     CDS             54602..54799
                     /locus_tag="RD508_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HDT7735714.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASALVAMLGKAYGWNGTDMIVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            54810..>55372
                     /locus_tag="RD508_001104"
     CDS             54810..>55372
                     /locus_tag="RD508_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HDT7735715.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQIA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLA"
BASE COUNT        19197 a         9051 c        11467 g        15657 t
ORIGIN      
        1 gaaattgttt taagggtttc ttgaaagcct tccgtacctc gtttaacgaa ataatagcgt
       61 aataattgac aaaaatgata cgcagttcgc aattcttcgt tgtagcttaa cagctcatca
      121 acgatttctg tttgactaat tggtcgttta aacagtcgat gataatgccg tttgagtggc
      181 tcccatgtcg tggaatcttt gagtaagagt ttccaatatc gcttgagccg acggtacttc
      241 ttctgatttt cagagtgtga ggttcgaaaa cgattcatga tctggacacg taattgattg
      301 aagctgcgat tgatgtgttg gacaatatga aagcggtcag ttacgatctc cgcatttgga
      361 aagactgttt taagcaactg acaatagctg gcattcatgt ccatcactag gtacttgacc
      421 tttaaacggg cctttctagg aaagcgcagg aagtattgag ttagtttgta aagtctgcga
      481 tcttcaagga tcgtaaatag ctgattggtt gtcccatcaa cacaaataaa actcatggaa
      541 ccagaaacag aattcattga tttgaactca tccatacaca acaccgtcgg aaggaagttc
      601 atacgtggct ggtaatgctt cgttgcttca cgcaagatcc gtgtcaccgt cccatccgag
      661 acgaagtact tcttagcgat tagtttacgt gattgatttt cgtacagttc catgagaatc
      721 gcctgcttca gttcctttgt tagttgatga tgttcatcaa ctaagtccgt tttcgcagaa
      781 aaggtccttc cacaatcatg gcagagaaaa cgggtacgtt ttaattctaa aatagttaac
      841 ttttctttga ctttcaacat ctgagtgcgt gtcgtatagg aaccgttgcg gataatacga
      901 accgatcgac agtgttcaca ataggaagaa gagtcatcca attttccttt aataaactgc
      961 gcttgaacgc ctttatattc tttttcaatc agccattctt catcaaaaaa taaatgttta
     1021 tctgttaatc cgagtaattt tctagtatga ttatccattg agagactcct ttggtaggat
     1081 gacgttttgg tcgactaaat tttaccaaaa gtgagtctct ttttgagttg aaacgaagaa
     1141 aaagtgttag tagaaaatcg ccttcgattt tccaccaaca caaaatatta tagaaccctt
     1201 tttttttgct atatgacagg aatgaaaggt gtttgcaagc ttaatgtgag gaacactttc
     1261 catatctgtt ctatactgga taggagaagt ttggaaatat ccagaaaacg aaatcaatcg
     1321 aggtagccac atgaagaata aatggataaa tcgaagtaaa aaaaagaaag taacacaaag
     1381 atcatcagat aaagtcatcc gtctttttcc atcgtataaa gaaggattaa cggcagatca
     1441 agtcaaggaa cgaatagaaa aaggtgcagc aaataattca gtcgatccca cattcaaaac
     1501 aaatcagcaa atcgtattgg aaaacatatt tacgtatttc aatttgatct ttcttatctt
     1561 agccattttg ctttgtttag tagaatccta taagaacttg acttttttac cagttatcat
     1621 agccaataca ggaatcgcca tttttcagga aattcgatcc aaaaagatct tggacgaact
     1681 aaatgtttta aatacagcaa aagtcaatgt catacgagac gggatagaac aaacaataga
     1741 tatagaagac cttgtaatag atgacattgt tattttagag actggatatc aaattccagc
     1801 agatgcagag gtcgtggaag ggaaactgca agttaatgag gctttattga caggcgaagc
     1861 agatgaaata accaaagaaa taggtgatcc attaatgtcc ggcagtttca ttgtttccgg
     1921 aaaagcttac gcccgattag acaaagttgg agcagattcg tatatttccc agctgacagt
     1981 caaagccaag acaatgggag aaggagaaca gtcggagatg attgcttctc ttaatcaatt
     2041 gatcaaatgg attgggatca tcattattcc tatcggtatc ctgctttttt ctcaaagtta
     2101 cttttttaat ggaaacacga tcaaagaaag tgtcgttgca atggaagcag cattgatcgg
     2161 tatgatacct gaaggactgt acttgctgac gacgattgca ttagcattaa gtgcgactaa
     2221 actagcaaag caaagagttc ttttacacaa tatgaaaagc attgagacat tggcaagggt
     2281 aaatgtcctt tgtgtagata aaacaggaac gatcacagaa aataaaatgt ctgttcaaaa
     2341 aatgatcgtc tctaaaaaac aagaaataat cagtcagtca gatcaattgg aagcatgcat
     2401 tgctgactat gcaaaagcga tggcaggaga caatgcaaca atggaagctg ttaaagcata
     2461 ttttacaaaa accactgatc aatcctatca ccatgttatt cctttttctt ctgtccaaaa
     2521 attcagcagt gtagcgttgg cagacaaggt gtatgtttta ggagcgcccg aaatggtttt
     2581 gcgcgatcaa ttgccggaat atgcggaaga gtttgtttct ttcgctgaaa aaggctatcg
     2641 cgtgttggtc tttggtgtgt acgatgggat tcttgaagaa ccagtattga cagaagcagt
     2701 cacaccatta ggctatattc tgattgctaa tcctatcaga aaagaagcaa gagccacatt
     2761 tgattacttc aaaaaacagc aagtagccat caaagtgatt tctggagata atccgctcac
     2821 cgtatccaat gtagctgtcc aagcagggat ttcacatgct gatcagtacg ttgatgcatc
     2881 taaattatca gaagaagaat atgaagcagc tgtcgaaaaa tatacagttt ttggacgcgt
     2941 caagccagaa caaaagaaaa tcttcgttca attgataaag cgtaacaata cagtagctat
     3001 gacaggtgat ggcgtgaatg atattctagc catgaaagaa gcagactgca gtatagcgat
     3061 ggcttccgga aatgaagccg ccatgcaggc ctcacaagtg gtcttacttg attctgactt
     3121 ttcacgcatg ccagaagttg ttgcagaagg acggcgcgtt gtgaacaata ttgagcgatc
     3181 agccagcttg tttttagtga agaatatttt ctcctttttg ctctcactgt tttcagtgat
     3241 ctttgctctg acctatcctt tagaaccatc acaaatcaca ttgattagtt tgtttactat
     3301 cggacttcca tctttcttgc ttgctctaga agaaaacaaa aagcgaatca gagggaaatt
     3361 catcatgaat gtgatggaaa aagctgtgcc aggtggacta acagatatga tcgtagtcgg
     3421 tgcgttggtg atctgcgggg tgactttgaa tctaaataaa acagatgttt ctacagcatc
     3481 taccatgctt ttgattgcag tagggttcct cgttctctat aaaatctgtt caccgctgaa
     3541 taaattcaga agtcagatca ttcttttctg tgctagcggt aacttttttt cggtcatctt
     3601 tttgcataag ctgttttcaa tcaccggtat ctcagctgta tcacttttgc tgttgagcat
     3661 tctatttttc tcggcagatt cgatttttag gcatttgacc acattggtag aatatttgtt
     3721 tgaacgtaaa aatgaaaaag agcaaaagcc gtttagtcgc gtagctaaaa aatttctatc
     3781 gatatttaaa cgagaaaatt gacgaaaagt atctcaaaaa agagtaaaaa agaacaacca
     3841 ctcgtgtatc tttcgaagca ggatgagtca tccaacttta aaacgcacga gcagttgctc
     3901 ttttttacat tttcggaatg gtaacggtga aagtcgaacc tgttccaaga tgactgtcta
     3961 cagtaatcgt accattaagg agttgcacgt agtcttttac aatcgctaac cctaatccgg
     4021 tcccgcctga atgtcggctt cgcgccttgt ctacgcggta aaaacgctca aagatccgtt
     4081 cctgatcctc aatgtcgata cctataccaa agtcttggac agaaaacgat agatcatctg
     4141 ttgcctgata gcggataata atctcgctgt cgctttttga atattggaca gcattttcaa
     4201 tcagattttt gataattgga taaaggatat ctgttttagt agtaaatggt tcgttctttc
     4261 caatcaatcg aatcgtcaac cgtttctttt cgatgattgg ctgataattt tgaacgattt
     4321 gctggaaata aggttctgta taaattgtct ggatctcgta agaattctcg ccatcttttg
     4381 acagctggat gatttcccga atcagtttat ctaaccggat cgcatctttt tgcatgatct
     4441 caagaaaaga agtcagagtt tgcgggtcat cttttgcacc atccagtaaa gtctcggtaa
     4501 aaccaatcag tgaagtcaca ggagttttta attcgtgaga gacgttgcca acgaaatcct
     4561 tttgtagctt ttctaaacgt cgcactttcg ttaagtcata cgccacccct agaatctgtc
     4621 cggtaccttc tgaattagta aagtagcgca aactcaagtc taatgtctgc cgaccttctg
     4681 taagggtgat ctcctgatgg atcagcggat gctcaggagt cacttgatga atcagctgaa
     4741 tgagttttgg ctcttgaatg acttctgtgt accgctgttc aggttgatag cttaccacgt
     4801 ttaaatgtag ctgcatcttt ggattaagca gtagtaaacg agaatcagca tcatcaatca
     4861 ggaatacgcc aatcatcagt tcgttcagta acgtatataa ttgctcttct gtggtagtac
     4921 acgcccgata catcttactc atttgttcgc tcaacgcatt aatcgtctga tacaattctt
     4981 cccattgatc gggtgtttgc atgattactt ccgcctgatt aggattttgc accatttttt
     5041 ttagtacggg cagcacggtt ttcaatggct ggtttttttg atagatcaga taatagatca
     5101 ttcctgcaag aacaaggaag aaagacagaa agaagaaaaa gacccaacgg cgaaaactct
     5161 cagttctcgg taaaaaaacg cttgtcggtt ctgcgatacg taaaatggct tctaactggc
     5221 cacttttttt gactggtaat gcgacatata aaagatcctc attcaaagta gtacttttgc
     5281 gcaaagcgct acctaggttc ccaccattca atacggcttt gatttcggga cgggagtttc
     5341 gctgttcatt caatgtttca ttgtttgtgt caaataagat ctttccagta gcatccatta
     5401 aagtaatccg ttcgttcgac tgatggacga attcttccaa agcagttttg ttttgcgctg
     5461 cttggaggtt ttcgacatct aattgccgga tcagcagttg tgcttttttt gtcaggtagc
     5521 tttcttgctg ttccacgatc tgctgttgaa aataatggga aatcaattgc cagccaccaa
     5581 aaaacaaact aactaaaaga ataagaaaga agagacgttc ataaattttt ttccatttca
     5641 tcgtttgggt tcctgaaact tatagccaaa tcctctaata gtcaccaagt actttgggtg
     5701 ttttggatct cgctcgattt tttctcgcaa atgactaacg tgtacatcta cgattcggct
     5761 ttgtcctgcg aagtcaaaat tccaaatgcg gtctagcaat gtgtctcggt cgatcacacg
     5821 gtcttttcgt ttcatgaaat aaacaagtaa ttcaaattct ttcggtgtta gttcaatcag
     5881 atggtcgtct acggtcactt gataattggt caaatcagca gtgatttgtc caatcgatag
     5941 atattcaggc tcagcttcat cttttgattg cttacgaggt tcaattcgtc tgaatattgc
     6001 tttcatacgg gctaatactt cgcgaggact aaatggtttg gtcaaatagt cgtcagcacc
     6061 tatttctagg ccaatgatcc gatccacttg gtcatcttta gccgtcagca tcaaaatcgg
     6121 tgtttcattt ttttcttgac gcagccgctg agtgatctcc atgccatcca tcgttggaag
     6181 catcacatct aaaatgatga aatcaaatga ttgttctaat gctaattcta atccttcgcc
     6241 tccatctgtg gcactggtta ccttgtagcc ttctttttcc aaattgaacg tcaagagcgt
     6301 tacaatagaa ggttcatcat caacaactag tatttttttc attcaaatct cctttaaata
     6361 ggtttcattc tgtttatatt ttagcataga atcagtacaa agggctattt tacaaaagaa
     6421 ataaatggta taataggaag gcactttgct gaatagaaag gaagagcagt caatgattgg
     6481 aatcagtgca tgtttaggcg gtctggcctg tcgctatgat ggacagaaaa aagaagtacc
     6541 agaattgatg gaactagttg aaactggaga agctgtcatg gtctgtccag aagtgatcgg
     6601 cggattacca attcctagag atcccgctga aatcattggt ggaaatggat tcgatgtgtg
     6661 gaaagatcaa gcaaaagtat ggacgacaag cggcgaagat gtaacggaag cgtacaaaaa
     6721 tggcgcgatc aaagcctatc aaaaattgca ggaaaaacac attgatctag tcatcatgaa
     6781 ggaaaaaagc ccttcatgcg gaacccattc gatttatgac ggaagttttt ccggaataaa
     6841 aaaaaatggt gccggagtgg ctactgctta ttttattcag caaaaaatga ctgtgctctc
     6901 tgatgaagaa tggctgaaaa ctagaggtga gcagaatgga aatcgaaaag accaatcgaa
     6961 tgaacgcgct ctttgaattt tattcgacct tattgacaga aaaacaaatg aactacatgg
     7021 aattatatta tgcagatgat ttttcattag gtgagatcgc ggaagaatac gaagtaagcc
     7081 gacaagcagt atatgacaat atcaagcgga caagcaagat cttggaggat tatgaaaaaa
     7141 aactccatct tttttctaat tatattgttc gagaacaggt attggaaaat atgactgcat
     7201 atattacaga taagtacccg gaagataaaa aactacttga atatgtacag caaattcaag
     7261 caatcgaaga ataaataaaa ggaatgaaga aaatatggca tttgaaagct taactgaacg
     7321 tctccagcag gcgatgggaa aaataagaaa aaaaggaaaa gtatcagaag ctgacgtaaa
     7381 agaaatgatg cgggaaatcc gccttgcctt actagaagcc gatgttaact tgcaagtagt
     7441 caaagatttt actaagcgcg tacgcgaacg tgcggtaggg gcagaagtgc tggaaagttt
     7501 atcacctgca caacaaatcg taaaaatcgt tgatgaagaa ttgacgatca cacttggttc
     7561 tgaaacagca gagttaaata aatcaccaaa aataccaact gttatcatga tggctggtct
     7621 tcaaggggca ggtaaaacga cctttactgg taaattagcc aattatttaa agaaaaatga
     7681 aaatgctcgt ccgctcctaa tcgcagggga cgtatatcga ccagctgcga tcgaccaatt
     7741 gaaagtatta ggtcaacagc tagacgttcc tgtatttgat atgggaactg aagtcagccc
     7801 ggtagagatc gtccgtcaag ggatggagtt agcaaaagaa aagaaaaacg actatgtatt
     7861 gatcgatacg gcaggacgtc tgcatatcga tgaaacattg atggatgagt tgaaacaaat
     7921 caaagaattg acgcaaccaa atgagatttt gcttgttgtc gatgccatga ctggtcaaga
     7981 tgccgtcaac gtagctgata gcttcaacca gcaattaggt attacagggg tcgtcatcac
     8041 taaacttgat ggggatactc gaggcggggc agcactatcg atccgctcag tgacaggcgc
     8101 accaatcaaa ttcatcggtt ctggtgaaaa attgactgac ttagaagtat tccacccaga
     8161 tcgtatggct agccgtatcc ttggtatggg ggatatgctg acattgattg aaaaagcgca
     8221 gcaagactac gacgagaaaa aagcggaaga acttgcacag aaaatgcggg aaaattcatt
     8281 cgatttcaat gactttattg aacagcttga tcaagtgatg ggtatgggcc cactggaaga
     8341 tctaatcaaa atgatcccag gaatgaatca agtccctgga atcgaaaacg tcaaggtaga
     8401 tccaaaagat gttgaacgca aaaaagcgat ggtttattct atgacgccag cagaaagagc
     8461 aaatcctgat ctgttgaacc caagccgtcg tcgccgaatt gctgccggtt ctggaaacag
     8521 tgttgttgaa gtgaatcgaa tgatcaaaca attcaaggaa tcaagaaaaa tgatgcagca
     8581 aatgtccaaa ggggatatga acatcccagg tatggaccaa atgtttggtt caggcgtcaa
     8641 aggaaaacta ggcaaaatgg cgatgaatcg aatgatcaag aaaaataaga agaaaaagaa
     8701 aaaacggaaa taagatgaaa aaaacagctt cggtacagac tgaaaatgtc tactgccgga
     8761 gcttttctat cagcaatttt tattctttac taatacaatt actctaaacg aagaggtggc
     8821 acagatgaga tgtccgtgga gtgaacaaac agaaagtatg cggcaatatc atgatactgt
     8881 ctggggtgtt cctgaatatg atgaccaaaa gctgttccga aaattgatgc ttgatattaa
     8941 tcaagccgga ttgagctggc agacgatttt aaataaaagt gaagcattcg atgaagcata
     9001 tgatcgattc gatatcaaaa aagtcgcaaa ttatggagaa acaaaaatca gtgaactaat
     9061 ggaaaacaaa ggaattattc gtaaccgaag aaaaatcgaa gcagccgtcc aaaacgccaa
     9121 agcagtcttg aaaattcaag aagaaatcgg cagtttttca gagtatcttt ggtcgttttc
     9181 taatggaaaa atcgttgatt cttcttatca ttcacaagaa gaagtcccaa caacaagtcc
     9241 tctttcagat gaattagcaa aagatctaaa gaaaagagga tttaaattta tcggaagcac
     9301 aacaatctat gcttttttag aagctgtcgg gatcatcaat gatcaccttg acagttgttt
     9361 ccgcaaagaa gaggtcgtac gtatcggcag aaagggcgaa taaagcatgc gaaaaatcat
     9421 attttatggt gctataagtt tagatggcta tttggcaacg aaaacggatg atcttcaatg
     9481 gctttttgac actccaacag gtaagcaaac tacttatgaa gctttttatg aaacaatcga
     9541 tacgaccatc atgggcagaa aaacttatca ggaagcaaaa aaatatttgg agaccgaagc
     9601 aatttatcca gagaaaaaga atttcgtttt ttccacccac gcacaattac aattgccaga
     9661 tgctgaggtc gtaaacgaag atcctgttgc ttttctaaaa aatctacaaa tgacagaagg
     9721 aaaagatatc tgggttgtgg gtggcggtcg attgatcaaa ccgctattgg aacatcaaat
     9781 gattgatgaa tggtatatcc agattacccc tgtattatta ggggacggga ttcctttatt
     9841 ccaaaaagga acatatgaag cgcgttttga aatgctagac acgacacgat tcggtgaatt
     9901 tatcgaattg cattatgtac gaaagtagaa gtaaataaaa taaaaaaggc aactatatgc
     9961 agaaatgtcc tgtacatagt tgcctttttt attaccgtta tgctttttac tctgttaatt
    10021 tgttagaaaa atctagatac gcatctaaaa tcgtttggaa gaaacttaat gttccttcaa
    10081 cgatattacc attttcatca attagattcg caacgtttcc gatatatgct tccggttgct
    10141 gcaaggttgg cacattcaaa aagacaagtg attggcgtag atggtggttt gcgccaaagc
    10201 cgccgatccc acctggtgat gcagtaacga ctaaacctgg tttatgatcc caaacactgt
    10261 gtccataagg tcttgagcct acatctaaag catttttcaa tactgctggc acagaacggt
    10321 tgtattcagg agtaacgaaa acgacaccgt ctagtcccct cacttcctca cgaaaacgag
    10381 tccattcagc aggagcctgt tctggagttt cgagatcctc attgtaaaat ggcagatcat
    10441 cgatttttac aaatacactt tcgtaccctt caggaagcaa tttcgcaaaa gcttctgcta
    10501 cttttttgtt gtaagaatct tttcttaaac taccaataaa aaatccaatt ttttttgtca
    10561 tacgattttt cctccttcaa actatctata ataatcttac aaaagataag taactggagc
    10621 aaataaaaac acttactgac aaaagctaca tagaagatag attacttatt tttaacaaaa
    10681 aagaagtcta aaatcttcta ttttctaaaa aaaatcgaat ttaatcaagc tgtaaagaaa
    10741 aaaagcttta cagggtaaaa aaaaactgtt acactacatc ttgtgaataa aacaatggag
    10801 gtggaaataa ataatggcag ttaaaatccg tttaaaacgt atgggttcta aaaagagtcc
    10861 gttttaccgt atcgtcgtag ctgattcacg ttctcctcgt gatggacgtt tcatcgaaac
    10921 tgtaggtact tacaatcctt tgaaagaccc tgcagaagta gttttaaaag aagacttagt
    10981 tcttgactgg ttatcaaaag gtgcacaacc ttctgacact gtacgtaaca tcctttcaaa
    11041 agaaggcgtt atgcaaaaac accacgaagc taaattctca aagaaataag gtgaccggat
    11101 atgaaagatt taagcgactt agtcttaaca atcgttcgtc cgctagtcac ttatcctgat
    11161 caagtcaagt tagacgtcgt agagtcgaaa gacttttacg agtacaatct aacagtggct
    11221 cctgaagata ttggccgtat cattggaaaa caagggcgtg ttgctaaagc aatccgcaca
    11281 atcgtttacg gtgttcggat caatgcaccg aaaaaagtgc gtttgaatat catcgatgat
    11341 aaggaaaagt aaataaacgt gctgtactcg aattttcgag tgcagctttt ttgttttttt
    11401 tattaattga agaaatgatt atttggcaaa acaagcaaga aagcgtatcc ttataggagg
    11461 agggagtgaa cagccaatga gaaagaaaat gttatttatt ccatttgctc tattgttaag
    11521 cgcttgtagt tcggttactc aagaatcaga caatacacat ctatcaagca gtatatctga
    11581 aactgttacc agtccagaaa aaagtagtac caaaacggct tccaccactg aacaaacaat
    11641 ggctacctca aataatgaga aaaagactgc tttagaccag ttgaaagaac aacagccaaa
    11701 tgttcccatg cctctagatg taccagtctc ttcaggctat ctcaatatcg cagcgacaca
    11761 tacaaagcaa ggttattcta ttttatatta cagaacagat cgtcccctcg ggttgaatgc
    11821 tgacgaattg aatcaagaaa cgcctattgc aacctatcta tatcaatatg ggtttgcttc
    11881 tagtcaagaa acaatccaag ttttgcagcc atttgagatc gacacaaatg gtcagcaagt
    11941 ggacttaggt tctcgaatca cagggtatca gcaaggtgca gcaggttcaa gttttcttga
    12001 atggcaagaa ggaaactggc gtattcgaat ccgtgggaat aatatagaag gccaagatcc
    12061 cttactatta gctaaagaaa tcgtagctta tttggaagaa aacagtctac cagcacctga
    12121 acaatttggt aaaattactg ttgatatggg tgatacgacg aatcgagccg tagaagtaag
    12181 ctggcaagaa ccgaaaaatg cctatacgat cactcatcaa gatcctatgt ctgcgttgaa
    12241 gatggcagtt tctatgaaga ggttgtgaaa tcagcgcgct gatctgagcc catcatttaa
    12301 ctccaagtca caggaagtaa tcaaaaatag cacgccgcat ttttgcataa ttttggctta
    12361 ataccttaaa agaaaactag aattgcctct tcacacatgc taaaataaaa cagacaaaaa
    12421 agaaatgggg atataagttg actgaatact tgaatgtagg aaaaatcgta aacacacaag
    12481 gtatcaaagg cgaagtccgt gttatctcaa caacggattt cccagaagaa cgttacaaaa
    12541 aaggaacggt gctaacacta ttccaagacg gaaaagcacc tgtggaatta acagtcaaaa
    12601 gtcatcgcaa acataaaaat tttgacttat tgagttttga aggacatcct tctatcaatg
    12661 atgtggaaaa atatcgggat ggcatattaa aagtgtcaaa agacaactct gtagatctag
    12721 ctgaaaatga attctattac catgagatca tcggtctgca tgtattagaa gatggaactg
    12781 agttaggtaa agtaaaagaa atcttgtcac caggtgccaa tgatgtttgg gtcgttcaac
    12841 gtccgaaaaa agctgatata ttgcttccat atatcgcttc tgtcgtcaaa gaagtcgatt
    12901 tagaagctgg agtggtccgt gtagaaattc cagaaggact gattgacgat gaagattgat
    12961 gtattgactt tatttccaag aatgtttgaa ggtcctatgg gggaatccat catcggtaag
    13021 gctgtagata aaggattatt agatatcaat atctctaact tccgcgatta ttcagataac
    13081 aaacatcaga cagtagatga ttatccatac ggcggtggag caggtatgct gctcaaagtc
    13141 cagcccatct atgataacat ccaagccatt gaaaaagctg caccggatgt caaaaaaaga
    13201 gtaattcttc ttgacccagc tggtaaacga ttcgatcaga aaatggcaga agaattttca
    13261 caagaagaac acttagtatt catttgtggt cattatgagg gatatgatga acgtatccgc
    13321 acattagtga cagatgaagt ttccttagga gattatgtcc ttactggggg agaattaggt
    13381 gcgatggtca tgatcgatgc aacagttcgg cttttgccag atgtgttagg gaatcagact
    13441 tcagctcaaa cggattctta ttcaaccggt ttattggaac atccccaata tactcgcccg
    13501 gcagaatata aagggatgaa agtaccagaa gtattgacaa atggaaatca taaattgatt
    13561 gaagaatggc aattaaaaga atcactaaga aggacctatc aacgtcggcc tgatcttttg
    13621 gaaacacttg aatggacacc tcaaatgacg aaatttttag aagaaatcaa gaaagaagaa
    13681 caagaaaaaa cagcagatga agccaagtga ctttttctaa aatcttcttt acagtaggtt
    13741 gataatatgt tagtatttta tggtgagtgc aaaagcactt aactattacg atattccgct
    13801 gtgagaaaag ctcataagaa tatttggaat aaggagaaga aaaccatgaa tccattaatc
    13861 gaagaattaa caaaagaaca attacgttct gacatcccag cgttccgccc tggtgacact
    13921 gtgcgtgttc acgcaaaagt tgttgaaggt actcgtgaac gtatccagtt atttgaaggt
    13981 gttgttatca aacgccgcgg tgctggaatc agcgaaactt atacagtacg taaagtttct
    14041 aacggagtgg gcgttgaacg tacattccca ttgcatacac cacgtgttgc aaaaatcgaa
    14101 gtagttcgct acggtaaagt acgtcgtgca aaattgtact acctacgtgc attacacgga
    14161 aaagctgctc gtatcaaaga aatccgtcgt taatcattgt tatcagactg agaaagaacc
    14221 cttggtattc aagggttctt tttttattat ctgttttttt atattaacga tttctatttg
    14281 gtacattttt gattaataaa aaggggcaaa aaaggggcaa caagttacag tttttctata
    14341 tcttctttca atttttcttt tactcctttt gtcacatgca aataaatctt ttcagtgata
    14401 tcactatttt cgtgcccaac gcgatcctga atagcataca gaggagttcc tagttccgct
    14461 aattttgaaa tatgggtatg tctaaaaata tgtgaactaa gttttttatc aatcttcatg
    14521 tcagctttat gatttctcaa ataggtgtta attgctgtta gttggaaagg agttcctttc
    14581 gttgtttgaa atagaaattg acccttcgga tttaattcta gaagctcatt gtaaatagct
    14641 atcgcttttt ttggtaaatc aatttctcgc attccagcag cagtttttgt agaatcagat
    14701 tttttcatat cagctattga acgttctcta tacatcatcg tcccatttat aactactgat
    14761 gcattattat tggtaatgtg tacatcgtct ttacttaatg cgattgcttc tccaggtctc
    14821 attccagtca aatatagcca ctggaaaagg agagaatatc ttttattgtg tgaagttgtg
    14881 aaatctacta gtcttttata ttcatcatct tctaaaaact tatctttaat ttttatcgtt
    14941 tttgactctc gtttataatc aataactact tcgttgatag gatttttttc tacatagcct
    15001 tttttcatag cgtatgaaaa aagaagattc aatttggatt taattacact gacgtactta
    15061 tttgacaagt catctttata tatcatatct tcaaaaatat tatttaaatc tactgtatta
    15121 ataccagaaa cgatgtaagt ctcaggcatc ttcttcttta tagtgtttaa gatattattc
    15181 gtaggataat atgtagactc cttaacttgc cttttgtaaa taactaacca ttcttcgaca
    15241 agctcatgaa atgttagatt aggcttctgg agtgtttttt catttagttt tatatcaatt
    15301 tttttattta actccagtaa tgccactttc tgagtttctc gagacttatt tttataagta
    15361 atgctcactt tttttctttt tctagttttt ggatcaatat atcgttcatt atatttatat
    15421 actttttttc cgtttttatc agttttggtt tcaatccaca ttgttttcat ctcctatttg
    15481 ttgctataat aggaatggat aagtaagccg attatagcag gtttattttt catcacgtcc
    15541 acaaactttg gcgagggagg gggcgtgttt ttgtatttta acgatttata ttgaatgttg
    15601 attcagcact ttcagcaact gtactataat cagacggatt atataacact ccggttttta
    15661 tcgttacttt tgtaatatcg ttaactttag atggatctaa gtaagctaaa ctataaaatt
    15721 ctttactttc agtttttttg aaaaacgagt ttgttgtcat tgtatgcata agatcgtctg
    15781 aactgaaatc aatttgttgg ccgttatcaa gtatggcgtg tgcaagccca ttataaccat
    15841 aatctacttc agaattgttt ttaactttga atgcaatttg taaaccataa aaatttcctt
    15901 cactatcttt gtgattattt gcatcgtagt aaccagcagc gctagggtca gcataattgg
    15961 aatacttgag tagtttgata ttagatatat aaatgccgat atcaccaaga ggaatatctg
    16021 attgtgggct tgccgttcca attaattcaa ttttgccact tgtatctctt ttttctttgg
    16081 tccattgacc aactttgagg agggggccat caacctcctg tgaattttta gaagactgtg
    16141 ttgtactttc tgataacgta actgaagagt ctttttcgtt tgttttgcca gtattatcta
    16201 caacattaga ttggctacat ccggtaagaa aaaaagcacc aaatactaac cctaaaatca
    16261 cttttttcat tctttattct ccgtttctat gatattattt ttatgtagga tcttagaaac
    16321 gagatcttag tccgtgttgc agcacgggct tttttcttta taactttttt agagattata
    16381 ggcaaaatag taggacacaa aaatatatta ttgtattccg tatttagaaa atcctaattg
    16441 aacttcacca gaagtttttt gctgtgttgt acgcaatgct tcttcttcag acattccatt
    16501 ctgtactttc catgcaacag gcgacatccc gtatttgtta acaaaatcag taagtgataa
    16561 agtgtcagcg tcttgctgac cgcttgtttg ttggtcttct ggattttgtt gagatgctgc
    16621 ttgttgttct ttctgatctt gactgataat attgccagca tcatctgtag tcaatccatt
    16681 ttcataaagg gccacgccga aagcttccca ctctttgttg gaccaatttg cacgatcagc
    16741 tggagttgac tgtaaagtgc gttgtttcat ctgttcatat gtttcttctt gaggtgcggt
    16801 ttggattgta tcctgactgg agcttataac tgttgggcta ggttccgccg tagcttggtt
    16861 agagcttgta actgttgaac tagaatctgt cttagatgta gatttgctag tagaggaact
    16921 ggtttcagtt gtttcttttg ttttacttac ttttgtttct tggttagaag tggcatctgt
    16981 tgattcagct tttttattat ttgaacaagc tgaaagtagc agagcagtac ttaacaacaa
    17041 cataacgcta acttttttca ttttataatt cctctttctc gttgtaatat gtgtgctaac
    17101 acgggctttt ttatataaga aaacgataag cgctttctgg aagtccgtaa agattcttta
    17161 attcatcgat ttttttggga tattgatcat tatcttcttt ataaagagaa acaatgagat
    17221 tagcagcaaa gcaattagct tcgctttcag atttgcttct agatgttctt gttgatacat
    17281 agtaactgga taagccgcga tgaaaaatag cgtgacctaa ttcgtgagcg caaatgtaga
    17341 atctttcctc agagtctcgc agttcatcat ttaagaagat tattgcacga cctctaattt
    17401 cttgaaactg tcctttggga ttttcgataa aaggaacgta ttgaatttta atgcccatct
    17461 tttcacaaat ataaaaagga ttagcagacc ggtatttccg cttcaactcc tcgactaaat
    17521 taatcgtatc catctccata agctcacatc tttttgcctt tttctttgtc ttctttcaca
    17581 atatcccaga aggttccaat aaggatatct tttacgcgtt ggacctgttc aggcgtcagt
    17641 gtttctccgc cataagacat attgacattt gaatctagta atttatcaag ttcaactact
    17701 tcatcttttg ttgcccagtc aggaacttgg tttctaccga gtaaataatc agtagttaca
    17761 ttaaaataat ctgctacaag ttgtagtctt ttagtactag gagttctatt tttccattga
    17821 taaatcgtgt ttttaggtat atttaattct tcttccaatt gagttatact tatgcctctt
    17881 ttatgagcta attcctttat tctatctagt aaattcattt tcgcacctca caagctacga
    17941 aaacactaat aaaaaaatta gttaaaggtg ttgacaacta ataaaattgt tagtatactg
    18001 ttttcgtaag ctaaaatatt agctaaaaag acttgataac taataaacac ttcacggtcg
    18061 gcaaactctg aaatgtaaat tactaggcat ttctgtgtct tatttagcta tatctatata
    18121 ctaataaaaa tattagttat tgtcaacgaa tattagctaa ttttttagct tacagactat
    18181 tttttagaaa ggagctattt ttatgtctga gaatttagac ttaaaaattc gagcggagat
    18241 gagaaaaaga agaatgactt tcaaagaact agctgcgctt gttggtattt caggagctta
    18301 tttatcagat attctaaacg gcaatcgtga tggaaagaaa gcacaacagc atatcgaaac
    18361 agtgaaaaaa atattggaca tccgataggg ggggtaggcg atgacaaaac taaaaaaaca
    18421 agattttgta aaaaaataca attattctcc atctacttat caacgtcgaa tgtcggaact
    18481 aaaaaataca gcaattttct cagcggcgta tgaacgggtc acaggacaag aagtttggat
    18541 caatacagaa ttatacgata aatttttgtc tttcaaatcc tataacaggt tacgcacaag
    18601 aaagataaca cctaaagaat ttatcgagaa gcatttagtt gatttataaa aaacagaaca
    18661 ttttgagagg tgaaggttaa tgggcaaatt caacagagca ctagtattca gcacaccatt
    18721 catcatctac gctttaggcc tctggggaag cagacaagcg ttgataggaa cgattgttta
    18781 catggtttgg atttttatgg ggctggatga agctgagtac aaaacaaaaa agccagtcgg
    18841 gagggactga ctaatgaaaa aaagtttaat gactataaac gaaaaacaat tgaaagaaaa
    18901 ttttaatgat ctcatcaaag aatttgtaaa agaaactgga gaatttccta atcaaattca
    18961 tctagttgcg gaggggcata gccagtatca agctgtgaaa tttgagatga agaaacaaat
    19021 ctattgaatt tagcagtacc tctacttgta agaacattta ttgtaatgtt tttttcgact
    19081 aaagattcat cgtatctaaa aaccaacgta gtaatttttg actcatacgg tggaatggta
    19141 ataggtaatg acaacggagg aaattttgat agatcagcac ctttttttaa agatttacca
    19201 gaatacgcac gtataccatg tggaagttcg tcatacattg attttaccgt tacagaataa
    19261 ttatcaccaa tcattgtaaa agcatttaaa tgatcaggaa ttccagaaat cgaaaactca
    19321 ataattgtaa caggtaaaga actgttattt gttaacaata cagaatctat aatcctgaat
    19381 ttattttgat ggtaaacatc tggtttggaa tcactttctc tatctatcaa ccattcttcg
    19441 cattcagcga agaaatccaa ttttaaatta aattttttgt tttttctatc tgtataggag
    19501 atataaaaag caaatgttga aaatactaga gacgtaatag gcaaaataaa atctttaatg
    19561 gttttaacaa tgttattcca gtcaaattgt ttaataaagt caataagact caatttatac
    19621 caccaccatt ttttatctac attatatcaa agaggagaga agaaataatg caagaattag
    19681 taattttgaa aaataaagaa gctgtgacta cgagtttgca agttgcagaa agttttgaga
    19741 aaaagcatca acatgtttta agagatattg atgcactgaa aaaagatgtg tccaattttg
    19801 gacagatgtt ttctgaaggt aatgaaccag attcatacgg cagaaatcga cgagttttct
    19861 tcattagtag agatggtttt ttcttgttgg ctatgggttt tacaggaaag aaagctattt
    19921 acttcaaaca aaaatacatt gaagcattca acgaaatgga agatgttatt cgcaagaata
    19981 ctgttcctca aacaattgaa gatatgatga tctaccaact aaaagaaatg aaagatgtta
    20041 aaaaagatgt ttccatgctt aaagatacta tgcgaattag tgggcaacaa gagtttgaaa
    20101 ttaaacaaaa aggaaatata aaagttatgg aagttctagg gggtaaagaa agccgagctt
    20161 atgaagaaat cagcaaaaaa gtattctcaa aattttggtc tgaatttaaa cgtacctttt
    20221 caatcccaag atatggcgag ttacctcgta agagattcga tgatgctgtt tcatttattg
    20281 aaatgtggtt accagaaact gcgatccgca tggaaatcga tcaactgaac agacaacaaa
    20341 gacttttcgg tgatgaaaat gaatagagct gaagcgctaa gaatcgggac ggtaattgct
    20401 aatcgctggt ggagacacaa taaaccaatc atcctaagcc aacaacatat tgacaagcaa
    20461 aaagcatggc aacaaataaa aaagtgactc cgccggcaag caaagagtca caaagaaaac
    20521 acatcataag gagattttag catatggaaa aagaactttc cactctagat caatatttga
    20581 ctgatcctag ttggggcaaa tcgaatatca aggaaacaaa taatcgaaaa atcagacgaa
    20641 atcttttgac ggatgaagaa ctagcatgtg atcaagacga tttgggaaat tttgtgagta
    20701 tttgggatca tgtctatctt atccatttat cgaggaagtc caaaaaacct gaatatatct
    20761 atgtcatcga agatggcttg attgatgcgc tagaagagta tgacagagat aacttgattg
    20821 atatctctta ttacggatca ggtaagaaat acattgctga aatggaggca gaatttgatg
    20881 agtgaaaaca aagggacaac gacttttgaa aaacttttta gtcgcaagtt aaataaaata
    20941 ctcaagaaaa aaggaaattt tgattattta tcttgggctc acgcgtggga gattatgaaa
    21001 aagaatgatc cacaggcaac ggtaactatt aatgagtata aacactacag ggttgtttct
    21061 ggaactcatc aagactttct tgttgaggaa tataaacctt ttcttatgga tgaaacaggg
    21121 acttatgtat ctgtctcagt aacggttaaa ggacacacgg aaaccgagtt atttcctgtt
    21181 ttagattatc gaaaccaacc agttgttaaa ccaaatgcaa tgcaaatcaa taactcattg
    21241 aagcgatgct ttgtgaaagc attggctcta cacggactgg gattatatgt atttcaaggg
    21301 gaagatattc caacaccacc tagaatcgat acgaagaaat taaacatgct agagacgatt
    21361 ctagaagctt tcaatgagca gatgggtaaa gatatgacca aaaccttaat cgaatatgtt
    21421 aatgagcaga cagataaatt agggctctta gctgataacg ttgaaactat tgaacagtta
    21481 agctatgagc aatgtgcctt gatggagcga gcaatagcag ctaagagaaa agaattagat
    21541 aagaagtgat atgagtgttt aaaccattaa tcgattcata ttcagcggtt ctgaaaaagt
    21601 tcaaaggaaa agacataggt gcaaccatca atgaggaagt gaacattgat cgactaaaga
    21661 cgatgtatga cggctacgat ggtgatcgag ttattgaaat tcgttttatt gatcctagac
    21721 gtttcacagt acagcaacga aacttcatct atgtactcat aggcgatatt ttcatcgata
    21781 caggcatgcc aacggacttc tggaaggaat tcttttactt ccgtttcgaa ggtgtcacag
    21841 ggcgcgaaat aagcctcaaa gatgaatcga atacgactgt gagtgatgcc aatatcttag
    21901 caaatatcat cttagatttt atctttgaac atcatattcc tttcaaagaa ggctatgaga
    21961 ttttaccagc gaatcaagaa tattacttct acaaatgcat cacaaaaaga gtctgctgta
    22021 tctgtggcaa aacaggagct gatatcgatc actttgacaa agcgctagga agacgaaagc
    22081 gcaaagaagt tgatcattca gagtacacat ttgcagcact ctgtagaatt catcacacgg
    22141 agaaacacaa aataggtgtg accaatttca aaaataagta tcaaatcaaa gggattaagt
    22201 taaaccagga gacaatcaag aaattaagaa tcgggggcta atgatgatta atttaaacgc
    22261 agtagcgttt gaacaaacat ggcgcactaa gtataaaaaa atgagtccaa gagacaaatt
    22321 gttcttagaa atcatgacat ttgctttcat tggtacacaa gctgaacaaa gcgatattag
    22381 tgttgaaaaa attaagacga atagattagt taatggaatt acagagactt gttaccagta
    22441 cacgattatc gtcgtggatg aggaggaata attttggcag aaagaagaat gttcgcaaag
    22501 acaattattg attctgatgc attcctagat atgcctttat cgacacaggc attatatttc
    22561 catctatcaa tgcgcgcaga tgatgatgga tttattaata atcccaaaaa aatacaacgt
    22621 atggttggtt gtggtgatga tgatttaaaa ctgcttatgg caaaaagatt catcttagtt
    22681 ttcgagagcg gtgtgatcgt cattaagcat tggaaaatac acaactatat tcgtaatgat
    22741 cgttacaaac ccacgttata tcaggatgaa aaagctttac tagcagacaa agataacaaa
    22801 gcttatacat ttgcagaaga gctttctaaa catgatgaaa aacttggtat accagatgac
    22861 aaccaagcgg tataccaaat ggatacacag gttaggttag gtaaggatag gttaggtaag
    22921 gatagtaaag agataaaaga tttaacgcct tcgaaaaaat cgaaggctaa gcccatccgt
    22981 cataaatacg gagagtataa aaatgttctt ttgtcagatg agcagatgga gaaactcaaa
    23041 acagaattcc ctaatgatta ccaagagcga atagaacggc tatctgagta ttgtgaatca
    23101 tctggtaaga cttataaaaa ctatttggca actattcgaa gctgggcaag aaaagaaaaa
    23161 agtgaatcta agaacgcaag cagtggatac aagcgcacag gaagacgaga gaagcttcct
    23221 gaatgggcaa tcgaccaaga agcctatctt aagaaaaaag cgctagaacg agctaataga
    23281 caatcaaaag caccatttta agaggtggaa aattgaaaat cgattatcta gaactaatta
    23341 atgaaatagc gaattataaa actggcgagg aaatagacat cctgagagac gtatatgatc
    23401 aactcgaaga agctggaatc gaaggaatta ataatgatcg ttcgagttgg agtaaactca
    23461 gatactattt cgcactttat atcgatgcaa cacaattaag aaatttagct tatacaaaat
    23521 tactatttgt tgattgcatt aaaggattgc aaaaacatct tagtgaactt gagcaggtgt
    23581 aatcagatgg atctaaaaac atttacagca cagatcgaac taatgcatca agaagcttta
    23641 agacaaagcg cctcgtacga agacaagtgg ctcaacacgt tccatggtgg acgtgagagc
    23701 gcacttgatc aagtactcaa attattgaaa ggggaacgtc gggatggata agaaagcggc
    23761 aatgaaacga atcatcgaac tgacacattc tgagaattgg caagaagaca aagaaatagt
    23821 tacagaagtc caaaagctcg gtaaatcaat gtggactgaa aagcccaaac ggagaacgcc
    23881 gagaaagatt gcaatttggc atggtgatcg aattctagta acaggtactg ctgaacagtt
    23941 atctgaaatt actggtctga gcaaaaacat catctgggat agagcaagga gcttatggat
    24001 tgattcaaaa ggacgacaat ttaggtatgt ggaggagaaa aaatgaacga actaatcaca
    24061 aaagtagagc agtgggctaa agacaaggga ctggatcaag cagatccaaa agcacagttt
    24121 ttgaaagtag ctgaggaatt cggggaaatc gcttcagcaa tggcaagaag taatgatgag
    24181 ctatttaaag atagcgtagg agacgtaatc gtcacgttga ttatcctttc catgcaaaaa
    24241 gggacaaacg tacaagagtg tttagaaatg gcatacaacg aaatcaaagg gcgcacagga
    24301 aaaatggtag atggtgtatt cgtgaagtcg agtgatttgg aggacagcaa atgataggtt
    24361 taacaatatt ttggtgtgcg attggtggtt tactagcatt tctaggatac tacctcatct
    24421 gtgaaagtag aaaaggaaga aaatatacag tgacaggtat tgtcctgtta attatcggaa
    24481 ttctagttgc agttggagca gaactgaatc tttatgtaaa tggtacacaa gaagatttgg
    24541 tgcgatttat gttttggatg aagaattagg aggaaaaaaa tgaacgaaaa caaattaatc
    24601 aaattaggtg tagcaggagc agtaatcgta ggtattggag ttatcggagg atttaagttc
    24661 ttcgaaaaaa tcgataatgg atatgtgggt gtgcgctatt caatgaacgg cggtatcaaa
    24721 gatgaagcac tgacgcaagg tgtgaaattt gtagggattg acaaagtgat ccaatatcca
    24781 attcgcttgc aaactatcca atcaaaaaat atttcagtat ctacaagcga cggcaaaaag
    24841 acaacgattg atatcaaata tgactacaaa gttgattcaa ctaaagcagc aaaaatgtac
    24901 aaggaatttg ggaatatcac ttcggaagat atcgaaagtg gatggttaaa atctaagctt
    24961 caaaaggtcg ctcgtgaagt ttatgcgaaa tatagtctgc ttgatgtcct ttcaggagat
    25021 tcctctaaag ttgaagctga ggtattaacg aactttgcta aatcagttga atctaaaggg
    25081 tttgaagtcg aagacgtaac acttggtgtt ccagatgtcg ataaagaaac acaaaaatca
    25141 atcgatgcga tcattcgagc tggtcaagaa aatgaaaaag cgaagctaga tgcagaaact
    25201 gcaaaaactc aagctgatag tgaagcttac aagaaaacaa aagctgcaga agcagaggca
    25261 gaatctaatc gcaaagtcgc cgaatcagta acagacaatt tgattcgtta tgaagaagct
    25321 caagctcgca aaaagcatgg atgggtaaca gtaaatggag cagatactgt agttacggat
    25381 gaagcaggca aataatatgg gattctttat ggctaaaatt ctcttgttct taggtttagt
    25441 aggagcagca tatctcgtgt atgcgctcct ttcccaaact gatgacaaag aagatgacaa
    25501 caacgatgaa atgaaatttt aggaggagaa ataatggatc tcattacaca atacagtgat
    25561 atcatcctca agaaaatcat ggcaaagatt cagaaagata aaaaagcaaa agaacgagcg
    25621 gaattagtta agttggaaat ggctgaaaca ggagtaggag tgcgaagtag caggcattgg
    25681 aaagcagcag caaacattga attttattac aacgaaattc aaaaagggtt cgatcagatg
    25741 cgtgagctgg atcggcaaac aaattggagc aagaaacttc atcaagatcg tttcaaattt
    25801 gtagagaagt ataaagaaat attagaagag tatttgagga ggacagcgaa tgataaaaaa
    25861 gctcattcaa ttcagcatgg atttatatga tatcgaatca ggagcaacag tatctgtgga
    25921 gtctgatcat ttaatcataa gttttgctga cgaacgtcaa attatcatat gggtagttga
    25981 cgatatgcta tatccagaaa ttgtacatga ttttgaagaa tcaaaagcgg ttgagtttga
    26041 aatagtgaaa aaagtaatgg aattgattga aaaatacgag gaggacagca aatgataccg
    26101 aagtttagag cgtgggataa gcgagaaaac acaatgagag atgtagctgt cttacatttt
    26161 actaaaaacg gcaaaacaaa ctttattgaa tattggataa atcctaccga attgaaatca
    26221 tatcacgtgc gaaacatcga cctcatgcaa tccacaggaa tgaaagataa gaatggtgtg
    26281 gagatatttg aaggggatgt agtaattaca tcaaaaggag cgattggata tgttgcgtat
    26341 cttcaacaag aagccggctt tgtagttgta ctaaagaaaa gtgattatag attaggccat
    26401 aggaatactg gcgaaagtta tgatgtagca actgctcatg aagtcatcgg aaatatatac
    26461 gagaatagcg agttattgga ggtagagtga ttatcttagc tactgactac atcgattctt
    26521 taaaagatga aaatgggaat gtcccagcat tgctaaattg tggaattaaa agcaagaata
    26581 gaatcatttt gttacggata tcggctgatt tagcaaaata tctttatctg agcaagacag
    26641 cagtatatta cactgcggct acacgttatc agtacaaggg aaaaacaatc agtcaggatt
    26701 attatgatcg tttaatcagt cctgacatgc atggaaaatc aaaatcagcg atcaagttat
    26761 ttggcgcaat agagatatat gccgatgatt ttccaaattt atggttgaag gaggaagcgg
    26821 aatgaaatac gaaataccac taagtgaagc gggcattcaa gcaattatca atggtcggga
    26881 ggttaataaa aaacttcctg atggtactga attagtcatc agacaaagtt atttgaaaga
    26941 tatggcagct ccagtattaa ttgatcgttt taacgtgact gattctgtgg tagagaacca
    27001 cttgaaagaa tttcgatcaa gtataaacga cactttcaga ttagggagtt gattgacaat
    27061 gaacaccaga caccgcagag tagcaaaact aagaaaacag gaactgaatg tactaaagac
    27121 aaagtttgaa aaagaatatg gaatttcagc agaagaaaca tataaagtgg caagtcagtt
    27181 tgttgctgat gcgagtgaga ctattcgtaa gtttgggatt tcgatattaa atgatgatcg
    27241 taaatgggag gcagaaagat gaaactaaaa gacggatttt acactgatgc ttatggaatt
    27301 ggtggtttga tgatggatct accaactaag aatcctataa agcaagagga atcagaaatt
    27361 aaagtcggtg acatggttcg ctgcgaagca gaagggttca tctatccatt tcgtggatat
    27421 gtagagcatc tctataatca ctcagcgatc attcgcattg aaaacacgat ggaatgtgac
    27481 aagcggttag cgaaaagcaa agagaattta gcagtggtga gattggtgga tatggaagtt
    27541 ataaaatctt aattttgctt ttttacaact atcctacaac aatgagcgtt attccacaac
    27601 tggaaggaga agaggcaatt gtgaacattt tagagaatat agatattaag caaacaagga
    27661 aaaatgctag acgattacta aaaagataca gaaatttaga acgtttggtc ggaccagtga
    27721 aaatagactt ttccgtgatg actgttacca aaaatttgaa attcacaatt gacagtcaaa
    27781 acgaagaaat cattgaagcg ataagtactc gagattcggt tatcgaagca ttaacacggc
    27841 taagtagaat ccatttccag gtactttatt atagttattg ttttcctaat aagatgtcaa
    27901 tgtatcaaat aggagaaaaa ttaggatatt ccgatagaac tatcgagaga atgaaggcag
    27961 tagctttggt tgaatttgct gaggcgtata aatcaggaga actcatttca cgtacaaaat
    28021 aaaaaaagtc ggattcctcc gactatgaat aatatttccg acataagtat tatatcataa
    28081 ttgggggaat cagaggatgg tacttttcga tgtaaagaaa tatgagacac caagcgcgaa
    28141 agatgttgat atggaacgca caaaacataa tgtcgctgtg tttctttcag catatctatc
    28201 agctagatgt agagtagggc aacctcgaga accaaaagtg acagcatctt attccttggt
    28261 tccaccttct acagctgatc atatatttga agcagaaaga atgctgatcg ataaagaaga
    28321 agcacaggaa gaatttgagt atctgcataa attgtttgtt cgaggctatt cagcgataca
    28381 gcatccgcat aagcctgatg tgactgaaag gcgcaagaag atattctatg atcgttatat
    28441 caatggtctg cccatttatg taactgctca aaggaataat actagcgaag aatcggttaa
    28501 agtagaatca aacagaatta tcatccaatt tgcttcatcg ttagaactgg ttgctttcaa
    28561 gtagccagtt tttacacttt ttataccctt ttattaccaa tttggtttcc attttatacc
    28621 ttttttatac caatcactta cctattcaac gttgtattat gatagtgtcg aaagattagt
    28681 gataggtctt agacaaaata aaatgtaagg gaggaaatct ccctcatcgt tttaaattaa
    28741 gcctcgatag acagcagcgg aaatattaag aataaggatg tgaactcaac tccttctaaa
    28801 ttgttcttat tatctatcat ccgttgctgt ctattaattt atgtattgga gggtatataa
    28861 aatgaataac gcttccgaaa aaattgatca actaactatt ttagtaaacc aaagaatcga
    28921 agatattatc aaggaattcg aaggtgaaaa gattaagagc ataaagctta ctttaatgga
    28981 tcataagttc gaactaaatt cgacaaaaag gaagatcgtt gagcttatag aaaaagaaat
    29041 tgctgtccag atcaatgagc aacaattaac taattaattt atgcatcgga ggaaaaacga
    29101 atggataaag aaagtgcacg agaactttat ttgagtaaat tcaaacgtaa caacaaacca
    29161 gaagaagttt ttggatcaaa cgttaaagag gttggagaaa aactaactca attattaaaa
    29221 gaagaagact taacatatga cgaagcatac gcaagtcttc agtactgtta caatctattg
    29281 aagtatgagt ctaattttct gaaacttcaa tagtaaataa ttcgtaattg gattctggca
    29341 acaaacaaaa attgaatttt tttccatcaa tatattccgt attgtaagcc aatgtagaaa
    29401 attctctata gtcttctatc tgcagattgc ctataaaagc tttaattttt tctaataata
    29461 gttggggatg atccaaaagt tttactgatt gtctaggata tgaaaaacta tcattccatg
    29521 tcttagcagc ttttgcccaa aggaatcctt tttccgcacc acttgctatg gatatctttg
    29581 ggtttgaaaa gtcaaaatct tcatccaaac tttcttgaat cacagaccaa cctgtttcag
    29641 agagttttaa aaagtctgca ctgaaaattt tgcaaccatt cttaacatac agtttaacag
    29701 tataattatc agggtctaaa caatttaaaa taaaatacgc agcttgaacc tcgcttaagt
    29761 tcatattttt caccacctat aatttatttc agcggaccac tcgctgataa ctaaaattat
    29821 acgcttagta tttattttca caatattaat ttgtcactgt ggcggaaagg gtagacgcta
    29881 tatctggtag gtatgcttga agaccagaga gacaagagct aagcgcaacc atgcaaggtt
    29941 cgattccttg ccagcgacat taaatgccta tgacggttac gactaccgaa aaaagatcgt
    30001 taagaagcta tacggtgcta cgtacggcaa tgtagtaagt gtgctatctg tacaccacca
    30061 agcttcggtc actgtggcgg aagtagaaga cgcagcggta aatggcgagt agcctcgtga
    30121 gagcctggta agttctcgtg agtggtgcaa tcccactcca gcgactttaa gcaaccgagg
    30181 catcggcggt ttaaaaatat aggggtgcgc aatttcgtac gcgttttgtg catcgtgtag
    30241 gttgctatta catattagat cactcatcga gtgatctttt tattttgaaa ggggagtaaa
    30301 caaatgaacg aaaaccaatt aagagagttg tttaaaacga atgaagcaaa caaaacaatg
    30361 gaggcgacat tctacgaaac tcaaaaaagc ttagcgttaa tcgcaaaaca atcaaagtat
    30421 ttctacgatc agcttattct gcaaggattt aatgaaggac aggctatgga atttatgatg
    30481 cgaacctttt ctgccagtaa ccaacagaaa gagtgataca taatgagaaa ctactggtat
    30541 atatcgctaa ctaatgaata tcctcgaacc attgatgatt gttcagtgcg tgttgtgcgt
    30601 tctgtacaaa tcaaaaagaa gtactccatc attgaaatga ccagagaagc tacaccaaat
    30661 gagatcgata agtacaatct tcgttactgt ggccatggat attggaaaga cgaatatatt
    30721 caacaaaaca ttgagaggta catcaaatga atgataacta tgattacatc aagttgattg
    30781 aaaagataag agcagaaaaa gatatggacg aactagctaa cttattcatg aacatcatta
    30841 gtttggtggg gttaaagatg gatgaagtag cggcactaaa ttatttcatc gctgagcaaa
    30901 caattagagc agagcacaat gctaagttct tgaaagatag gttagatcta gatgtaaaag
    30961 gattaggcgt tgaagggata ttcaaagtgc aagaagcctt agtgaatgtt tatgtcgaaa
    31021 agatgcaata gcattaacaa gtaattattg gatgttttca ggagggaaac tatgaaatta
    31081 aaagattata tcagggaagg gtataacatt gtaactacac caaatctagc ttacaaaatt
    31141 caagaagatt atcccaatgt tttagtgttt actgatagag ctttagatgc cattcctata
    31201 gggaagttat tagtagatcg ttattatagc aacaatccag ctgttcttag tgctaagcca
    31261 cttcaaaacg cttatgctat tgaacgcttt acttgcgagt ttactggata tgagacggta
    31321 gtaccaatga caggcgagac aggaagaaaa gtaattcaac agatcaaaaa gaggattgct
    31381 gaattgacgt tagatgatgg aagtaatacg aaccttctag aaatcaaact aagagatact
    31441 gactcagtac cagaagttta ttataaaggt caacgaatgg atgagatgcc gataggtctt
    31501 gtcgatatta cttatcattg gcatacggaa gaatatgaat gccaagtacc aaaaggagct
    31561 aacgacatca ctattgaata ttatgattca cataataaca agtacttaga tagaaaaatc
    31621 attgggcaca agagagatat gtaaatgatt gatgtttcaa ctaaacaagc aagagctagg
    31681 ttctatggat caactgagtg gaggaaactt agaagtcaat gcttagagcg agatcattat
    31741 gagtgccaat ggtgtaaagc agagggtaga ctaacaactc aacatgattc aattcttgaa
    31801 gtggatcata taaaggagct ggagtatcat ccggatttag ctctagatat aaacaaccta
    31861 agaaccttat gcaaagattg ccataacaaa aggcacaacc gtatgaaata tcgtggccaa
    31921 caaaagaaaa gaaagtggga tgatgaatgg tggtaagaaa aacagcaaac agagatgatg
    31981 tcaaacgagc agaagcaatc gctatggttg ataaggctat tgataagttg gttctattta
    32041 agagtcagct cattgaagaa acaacaactg tagaggatat atctatcaac aatagactaa
    32101 taggtaacgc taatgaagta acagggacat ttaatattaa tgtagacatt gattatacct
    32161 tgagtccatt tgcacatatt gtagaaagca acgagcaaga cggctgataa atcagtataa
    32221 agcgaagata tatagagtga aatacccccg gtcaaaagat tttgagaaga aataaaattt
    32281 ttgggaaccg gtggatgggg ttaattctgc aaatgcaacg tatttatttt acccctcccc
    32341 cctccgccgc ccctttagta aatatagaag gaaggtgatt ggtttgaatt ctaagttggt
    32401 tggcacgaga atgaaacaaa aaagaattga aaaaggattg acacaggctg atgtagcaac
    32461 gaaaagtggt atttctagta ggtattatgg aagtattgaa aatgggaaaa attcccctag
    32521 tatcgaaacg ttaaactcaa tttccatcgt cattggatgc agtttacatt tcttactcaa
    32581 tgatcgcatg gacgacatgg aaaaacgcgt agagctagaa aagaaacgtc tgcagaagat
    32641 attcgataaa attcctcatg acaaacttaa tttagttgaa gggctgatca ttcaggcagc
    32701 aaggttacgt gtcttgttgg atgataactg gaaggacatc attgaaaacg gggagtacga
    32761 gaaatttaaa caaagcgaga accaaattgc ttatgataga aagcgtccta tagttgaaaa
    32821 ttatgataat cgagataaaa cttatcaagc catcgtcaaa caactcaccg atttattacc
    32881 gcaaggcaca agagcggaca agaaaagtaa gttactcggt aggaaataaa aatgcttttt
    32941 aaccagcacg ttgatcaata tattcgtaaa tggaaatctg gtgagttaat ccttaacgaa
    33001 aaaaggatac aacttttaaa actaatagaa aaagaaatat tacctcgcga cgacatttat
    33061 tacttcgacg aggagcaaat aaataattat atcgagttta gtcaagcatg gtattttgag
    33121 ttagatgaat gggagaaatt tatttctgca ttcatttttt tgttttataa agaagatgac
    33181 gaagttgttt ttgatgaatt tgttattaat atggggcgtg gcgggggtaa aaatggcttt
    33241 atttcaacat tggcaaatta ttttgtcagt tcgcttcacg ggattgatta ctatgatgtt
    33301 tcaattgtag ctaatagtga gaaacaagca aaaagaagtt ttcaagaatg ctatcgagta
    33361 atcaataaaa aaggaaatga agatttaaaa gaagagtttg aagcgtataa aagcagtcta
    33421 accggtttag agacacagtc tgtttttgag tacaaaacta gtaatgcaag ctctcaagat
    33481 ggcggtcgag aaggtgcagt aatatacgac gaataccacg aaatggaaaa cacagatatt
    33541 gtagatgtgt tttctggtgg actggggaaa gttgatcacg gacggcaatt tttcattggt
    33601 actaaggggt ttgttcgtga aggttacttt gatattaaat atagagagtg tgaagatatt
    33661 ttaaatggtt tgtcagagtt caagggtgta tttccgtaca tatgcgaact ggatgccatt
    33721 gaagaaatgg atgaccccaa aaattggccg aaagcaaacc cggcactgca accaccgttg
    33781 aataaacgtg ggaaacgtct gtttaacgaa gtcatgaaaa agtacaaaaa gttagctaaa
    33841 gaaccttctg gacgctcggc atttgttact aaacgaatga attttcttga agacaatatg
    33901 gaaaactctg ttgcttcaag agaagaaata atggcaacaa atcgtccatt ttttgaacta
    33961 gatacggtac cgattggatc tctcgatttc ggtagtgttc gagattttgc tacttgcggt
    34021 ttgctattta aaaatcgaaa gaaatcggaa tacgcgttta aatcatttac gtttgcaatg
    34081 aaaaattttt gcgacgttca ttatggatac tcgttgaaag agcaattggt tggcagtgaa
    34141 aaacgggcac caataaaaac ttgggaaaaa atggggctga tgaaagttat tgacgagcca
    34201 tctttaaatc ctaagtatat tgttgattgg tttattcaag ctagagaaga atatggagtg
    34261 agagtaattg tcgtggataa ctataaggca gatattttag ggcctatgct tgaaaaagaa
    34321 ggatttgaag tagttcgact aaaaagacca tctagtttac atccattatt agctcctcgt
    34381 atagaagatg gatttgcaaa tcacaaattt atttttggag ataatccgtt aatgcgttgg
    34441 tttactaata atgtgtacgt aaaggaaacg caagcaggca aacaattctt aaaaaaagag
    34501 gaagtcaagc gtaaaactga tgggttccaa gcatttgtac acgcattgta caaagctaca
    34561 gaattagatg aacagattga ttacgatgat gcttttgata tgttggatga gattgaattt
    34621 taaggtatac ttttctttac aaaggggtgc tttcatgagg ataaaaggaa aaaacatatc
    34681 ttgggtattt tacatgttgg ggattttagc ttttacattt gtggcaataa aactatcaga
    34741 aattattatt ccaaatgaca gtgtagtttc aaagaatttg gttttagaaa gagctaaact
    34801 aattatttca attttaggac cagcattaac actaattgtt tttgttcgaa caattcaaac
    34861 tcaattagaa tcttcaaaaa acttaattaa agataacgtc agtaaagatt tttataattt
    34921 gctaaattta ttcaaaagta tacaggataa aatgaattct gaattattta gtacaattga
    34981 aaaaagaatt aaagtaccta taaataatat aaatacaaat ttagatgtta gagaaaataa
    35041 agaaactact aaagaagtac aggaggattt aaaagaatat agtgcatcat tgaataaagt
    35101 tttaagcgaa agcgttaaaa aaattaatga aatatttgag gataactaca aagacatagg
    35161 tagttatcta aaagtattcc ataggattct taaaatacta aataacaggt atgaatcaaa
    35221 agatatttcg catgaagaat acaaaatgta tgttggcata ttacgtagtc agattgaaga
    35281 ttacgaattt tatataattc ttataaattc tttgtttact cttcgcggaa cgggtatggg
    35341 gattgagtta attgaaacat cattctttgg tgatgaacta gatattgatt taaaacagca
    35401 tttcgaacat ccagagtttt taactgaaat cattaaggat aattttgttg aaaagaaatc
    35461 gtatcgtgaa tcagtaaaaa caagaaaaaa aaatagaaaa ctatttgaaa atagaaagat
    35521 aaatgataac ttattatctc ttttgagaat aagatacacg ttacaagatg gaaataaaat
    35581 tattataagt aatggagtat agtcctagaa atagggcttt ttattttacc ttgaaaggtg
    35641 gtgaaaatat gtgagtttat ttgatatctt taagcaatca ataaagaacg aagatccatc
    35701 ggattggatt cctgactttg tgtttggtga tgaagaatct gctagagcat atttgaaaat
    35761 catggctaaa agtacagttc ttgattttgt tgcaagaact atgtcaacgt tagaagttaa
    35821 gtttaaaaat aaagatggga catcagattg ggattacatt ctaaatgtcc gacctaattc
    35881 tgatatgtca gcagctacat tttggcaaaa atttttttat cggctcttag atgacaacga
    35941 agtgttagtg atatttacag atgataatca attgctgatt gctgatgatt ttagtcgaac
    36001 agagtatgcc gtgtatgatg atgtttttac aaatgtgatg gtgaaaaatt ttgtctttga
    36061 acgttcatgg gccatgtctg acgtcattta tatggaatat aataacgaag aattagaaag
    36121 gtttacacga ggtttatttg aagattacgc cgagttgttc ggacggattc tagaagttgc
    36181 aatgcgcaat aaccaaattc gtgggtctgt ctccattgat tcaacaggaa cggcaaatga
    36241 tgaaaaagga aaagatggta agactagatc tcaaagatta caagaatata ttgataagat
    36301 ttggaactct tttaaaacta actcagttgc aattgttccc aaagtgaaag gctttgagta
    36361 tgaggaatac accaataaac aaggcgtatc gaatcaatca ctagatgaac tgaataagat
    36421 gaagtcgtct ttaattgccg atgttgccaa cgccatagga gtacctacgg cgcttattta
    36481 tggcgaaaaa gctgaactag attcaaatat taaagctttt cgtaaattgt gtattgctcc
    36541 actagttaaa aaacttcagg acgaattggt ggcaaaaata attagtcgac aagagtacaa
    36601 aaacggggaa cgtatagaag ttaaaaaagt tctccaaaaa gatctattag agtatgctac
    36661 tcaaattgac aaaataacat ctggtggtgc gttttatatt gacgaagttc gtgatgaagt
    36721 tgattatgat gagttgccaa ataatgaagg aaaaattcgt attcgtacga aaaactatga
    36781 agaaactgtg aagggaggtg agaacgacaa tgccgaaagc taaaaaagta ccatttcagt
    36841 ttactaacga aattcagaat ggtaagcaca ttctcacctt gagtggaaat gtacagaaaa
    36901 aatattggcg tgatgatgat gtcataaacg ctaaagatat tcgtgactct ctagatactg
    36961 taaccgatga tattgtaatc aagttgaaca gcccaggcgg tgatgtgttt gaagggattg
    37021 agatttacaa ttatttaaaa gatcacccat caaatattac tgtagaagtt acagggcttg
    37081 ccgcaagcgc agcaacgttt attgtcgctg gtgccaatga tgtgattatg aatgttggga
    37141 cttctttgat gattcatgaa gcttctacat ttgcttgggg gaataaacag gacatccaaa
    37201 aaacgttaaa cgcattggaa acgatcgatg attctatctt agctatttat tcagataaga
    37261 ctggccaatc tgttgataag ttgcgtgaat ggatgaatga agaaaaatgg tttacagcag
    37321 atgaagctgt caaatatgga tttgccaatt ctgtgaagcg tgaagaacca caaaacgaac
    37381 ctcaaaatat tgcagcgatg attcaagatg ctgttgccgt tgcaatagcg aatttaaagg
    37441 aacctgttac taataaaatc gaacaagaat caaaacaaaa atcattaatc gcacgattgc
    37501 gaaaaggaga ataaagatat gttaaaaatt acagataaaa ctgcagatgc aaaaaaggca
    37561 tttaatgcta tttcttcgaa agaagatgca acacccgaac aaattaatgc tgctctagaa
    37621 gaatatgtaa ctgccattgc agaagatgcc ggcaaacagg tgcgtgctga atatgaagaa
    37681 ttgaaaaatg tgacggacaa ccgtgtatta gaggctcgtg gaattcctac actaacagta
    37741 gaagaaacaa agttttataa tgaagccgta aaatctggag gtttcgattc tgacgtagtt
    37801 tggccagaaa cgattttgga acgtgttttt gaaaatcttc aaaacgatca tcctatttta
    37861 ggcctcatta actttacacc aactgtaggt cgtgtcaaag taattagagc acgtcgtaaa
    37921 ggtgttgctg tttttggacc attgcataaa gaccttgaag gccaactaga tgctgaattt
    37981 ggtgcaactg aatttgttca acttgcgttg accgcatttt tcttaatttc taatgatacc
    38041 ttagatttag gaccacgatg gattgaccgt tttatcaatc tttctttaag tgaagcagta
    38101 cgtgatgttt gggctaaaaa aattattaca ggttctggta aagatgagcc aattggattg
    38161 cttaaagatc tagatggtgc ggtcacaagt ggtgtatatc cagataaagc tagcgcaggg
    38221 acattaactt ttgcgaaaga gaagattgtt cttgaacttg caggggtgat gaaaaaatta
    38281 tctaaataca catacaaagt agatggtgac gatgaaggtg aagtggaata ccgttctgtt
    38341 gctggacgag tgtatctaat tgttaatcct gttgattact gggatatcgt agctagagtt
    38401 acatttgcaa atttaaacaa tgtgtatggg actacgatgc catttatcgc tgttgatcat
    38461 atcatcgaat ctgtagacgt accagaaagt aaatgcattg catacgttga taaagagtat
    38521 gaagctactc aatcaagagc tgaaaaagtc tatgtatata aagaaacttt tgcaatgaaa
    38581 cgcgcaactt tgtatgctgt cgacatgctt ggtaatggct atccaacaaa taatgatgca
    38641 gcacaagtat atgacttgga ctttacagcg ggggagtaac gtcccctgca attggtgaga
    38701 taacaccgac gactgatggg gcagtcatta atctttcgta aatggggtta gagtatgaac
    38761 actgaagaat ttataaaaga atataaggcc cgatttcgta ttttccatac ttccgaagat
    38821 gaggatatcg ggaaacagtt agagagcggg tttgccgata taaaatctct aatcggcagt
    38881 tttgatcctt ccacttatga gaaaggaaaa gaattagttt atgaacgtac tcggtatcta
    38941 cggaacgaat cactagagta cttttacgac aattttcaaa caatgattat ggatgcatca
    39001 attgatctgg caggtgctgg atatgccaat taaatcaaat tataagaagc ctaaaattgt
    39061 agctggtgat ctaaatacgc cagttacttt ttttgagttt caacctaata agggtccaga
    39121 acctggtgat gaagaaaaaa aggaactgta tttttgtaca gcactagttt acaacccatc
    39181 aatgaaagat cgtgacattc ttggcacaaa agaaggcgtt acgataaaaa tacgggatcc
    39241 ccatcaatct tatattccta ctaacaaaca taaagtaagg atattagatt atcgatatgg
    39301 agataaagtt tgggaaataa tcgatgtctc accggatttg gaagaaaatt caattgtaaa
    39361 gatagtatta gaattaatta cttaaatttg gtgataaacg atgagtaacg taaagtttga
    39421 aggcgttcaa gaaacaatcc aagctttaga aaaaaagttt ggagaaaaga aaactaagac
    39481 attaacaaaa aaagcaatca atgttggcgc tgaaaaagta gaaaaacagt tgcaaacgga
    39541 catgaccgtt tttaaagaca aaggttatac gattgatgag gttgtacgta agaacgctac
    39601 gtatagaaat tacaaggcag aagctgaaat cggttggaat ggtcctcatc agcgttatag
    39661 aatcattcac ttaaatgaat ggggatatac acgaaaaggt aagcaaatta ggccaagagg
    39721 ttttggcgta atcactaaat cgcttaaaaa ttccgagcca ctatattttg atgctgttgg
    39781 ggaggaggtt aaaaagagat tatgaaagat atgctcaata tcatttatga ggctctttgt
    39841 ttgaatgagt atattcgttc aatgacatat aacgagaata ccgagcaata tcgtattaaa
    39901 ttttatgagc aacctgaaac cgccgataaa acagggccaa tgatcacact tcgtcctgta
    39961 gatacaccta acgaagcata tcacggaagt aacaaagagc tttctgtaga gcatatggta
    40021 cagattgatg ttgaatcgaa atatagagca acatgcaagc agattcaata tgagataaaa
    40081 aaagagatga aaaaactagg ctttggccaa atttctggtc aagggttaga tgaatacttt
    40141 tctgaaacaa aacgctttgt agacgcgcgt cgttacgaag gaaatacaaa aatttacgat
    40201 accgaatatt agaaattaag acacgaaaat aacgtgtctt tttttattac ccaaaattag
    40261 gaggaaaatt ttatgacttt agtaggattc aaaaaaatga caatcgggat ctttgacagc
    40321 acagggaaga ttccagcagc aaatttatat gtaattgaag gtgaacaaga caaaggggcg
    40381 actgtatctg ctgaaatcag tgggctatca aaagaaccat caaaagttta cggatcgaac
    40441 atcgcttact atgtctctca aaaaggaaca ggcgatgttt cagctacttt tggattgtta
    40501 gatttaccaa cagaagtaaa tgacaaaatt cttggttaca aaaccgatac aaacaaaatc
    40561 agcttcttgg gagaagatac tgagccacca tattgtgcaa ttttgatgga atcggaggat
    40621 ttgaacggcg atacagcaat gcttgcgatg ttcaaaggaa aattcagtcg tgaatctatt
    40681 aatcttaaca ctacgacaaa tgaagctttc gaaccagaag cagaagaata tgtattttca
    40741 gcgattgcca atgatgttga aggtgatgct aaaggccaaa cagtcgcaaa atatgttgga
    40801 gacgaagaag cttctattac tgctttgaaa gagatggtat ttcctgcagc gggggagtaa
    40861 ctagctccgt tgttggagca atcactccca ctattaatgg ggtaacagtt gaattaagtt
    40921 aggaggataa ctatgccaga tacatttaaa atctataaaa aaaatggtac tgaatttaca
    40981 aaagtcgcag agggtgaaag tccactttct attactggaa ttgcagcaaa tactcaagtt
    41041 gctaaaggag actaccaagc tacgcgtgtg gttggaggtc aagaatcagt aaaagtagat
    41101 attcctgcat ttaccactct tccaatttca gttactggtg tgacgttgga taaaacgaca
    41161 gctgaagtcg aacaaggcgg aaccttaaaa ttaactccta ctgtaacacc agcaaatgca
    41221 acagacaaaa caggaagctg gagcagttcg aatacagctg tagctactgt tactggaggc
    41281 aacgttacag taaaaacaga cgctgaagtt ggcggaacta cagaagtttc atttactact
    41341 acggatggcg gtaaagtagc aaaatgtact attacagtta ttgaaaaagc agcgggctag
    41401 tcttcggact agctttttta tttggaaaat aatggaggaa tctaaatggc aaaagtaaga
    41461 attgaattga aagaagaatc aggaaagaaa gtctatgaaa acatagacac aacaggtaaa
    41521 gattatcgaa aagctttaga aacaatcaaa aagctaaatg aagatggagt aatgatttgg
    41581 aatcgtttag acatttattt ggattttgct gtaggtatct tcagggatag caaattgaca
    41641 gctgaacaaa ttcttgatgg cttaccatct gagaaggtaa tgagcacatt ggacgacatc
    41701 ctaggagaag taatggggat tgaaagtaat ccagacccag acgcaaaaaa gtaacacccg
    41761 aagaagcaga agaaatgtac ttaaacctat gcagagagtt agtgaaagcg ggatggtcac
    41821 tatctgacat agaagataat tcctttgaaa tgatgatgaa aattgcgtgc acttcgccta
    41881 agaaagagaa acaaaaagaa gttgatctta aagacttctt gaaatccatg tagagaggag
    41941 gtaaacatat ggcaaatgga aaacctttag gcaatatgat tataaaacta gacttagaca
    42001 gttcagcttt ttcaaaaggt ctagccggag ctaaaaacgc tgttaaccat caaatgaaag
    42061 caatgaaatc acagatgcaa gtaatgaact cttcagggaa ttctctcggt gctttacaag
    42121 caaaatataa tggtttaggc ggagttctac aagcaaatga aaagcaagta gaattgctca
    42181 ctaaggctta taaggatagt tttgactcta atggaaacgc tactgcttcg actgctaaat
    42241 acgctaatca attgaatcaa gcaacagcta gatcagcaag ttacgaatct cagatgaaaa
    42301 caaccgttgg acagattgct cggatgaaag tggaaacgga agggattacg gggaaactaa
    42361 aagctaattc tgatgtattg attaattctg ggaaaaaaat tgaagccttt ggtaaaggag
    42421 tttctgggat aggatctgcc ctaactgttg gagtaacagc tccaatagtg gcaggtgcaa
    42481 ctgctgttac tagtgcagct atttcttggg aaagtgcttt tgcaggagta aaaaagacaa
    42541 atgatgaagt tgtagattcg aatgggaacg tagtttactc ctacagtgat ttagaaaaag
    42601 gccttcgtga tttagcgact aaattgccag caagccacca agaaatagcg aacgttgctg
    42661 aagcagcagg tcaattaggg attaagacag aaaatgtagt tagtttcacc aagacaatga
    42721 ttgatatggg cgaatctact aatatgtcag cagaaacagc tgcaacttct ttagcacgat
    42781 ttgctaatat aacccaaatg tctcaaaaag actttgataa attaggatca gtcattgttg
    42841 atctaggtaa caattttgct acaaccgaat cggaaatcac tgaaatggga ctgcggttag
    42901 cgggtgctgg taaacagatt ggaatgagcc aaggcgaaat tctaggattt gctactgctc
    42961 tatcctctgt tggtgtcgaa gctgaagcag gtgggtctgc cttttcgaag gtcatgatcc
    43021 agatgcaact agctgtagaa aaaggatttg gcgcttttga tcagctgaaa cagatggcag
    43081 aagaacaagg tgttccgtgg gttaatttag taaatgctgt gagagacggt ggaaaatcgt
    43141 taaaagcagt atcagagcaa atgggattca cttcatctga tttaaagaaa atgtataaag
    43201 aagcggacaa ttcgaaaagt tcgcttgaaa attttgcgaa tgtggcaggt gttacaagtg
    43261 aacaattcca gaagttgttc aagagtgatc cttcagaagc aatcatcaag ttcattcaag
    43321 gactgaaaga ttcagaaaaa catgggactt cagcaatcaa agttctggat gacatggata
    43381 taaaagaagt tcgactacgc gacagtttat tgagagctgc aaatgctagt gacatattca
    43441 aaggagcaat tgaaaaagga aacggcgcgt ggaaacaaaa tacagcttta acaaatgaag
    43501 ctaataaaag atacgaaaca actgaatcaa agctaaagat gttgaaaaac gaagtgattg
    43561 atacagcaat cgatcttgga ggtccatttg tagacgcgtt gcgtgatggt ctaaatgtat
    43621 caaaaccgtt gataaaaaac ttagggaata tggcgaaagc tttctcagcc atgagtgatg
    43681 atcaacaaag aaacattatc aaatgggttg gattagcagc agcagctggt ccagcgctga
    43741 agcttttagg aactggtact tcagtaatag gtaaagttac ttcaactact ggaagattga
    43801 cgaaaagcct tgttgattta gcagcgaaag cagcagaaaa gaaggctctg gatgcctttg
    43861 catcgtcggt aacaacagct ggtgctgcag ctgcaaagac agcaggagct ggaggtattg
    43921 gcgggttagt ccctatgatg ggaaaaacag ctagtgctgc aagtactgct gcgggcgcta
    43981 gcggaatagg cgcaatgaca acatcactag gtttgttagg tcctgctcta cttggtattg
    44041 ttggcgttgg tggcgcacta gcagttggct atggagcatg gaaattattt ggtgaagaag
    44101 cttggaattc ctcgcaaaga gtaaagcaat ggggaacaga tgtcggtgag gaaatagata
    44161 atactcttga cggagtacag aagaatattg aaggtgcaaa tggtcaattc ggtcttctca
    44221 aagagggttt tactgttgat gatgcgaata atatggcggc taatttcgca accgctggaa
    44281 catctttgga aacatcttta acaggtagaa taaaggcatt agacgatgca ctaaaagggc
    44341 tacctcaatc agttcaggat gccatgaaag aagtagctga atcagaagaa gaaaccttag
    44401 ggcaatctct ttctaaaata aaagacaaca atgaagaaat aaaaaaaatc agagaaagag
    44461 ccgcaaatca gaacagagac ttgactgttt cagaactaca acagatacag gatctgatga
    44521 aaggaacttc tcaagcgtat gtggatacgc tcgatgtttc tgctaaagac agaaaaaaga
    44581 tactatcagc catgaatggt gatgttgcac aggctacaga agaagaagcg aagacgtggt
    44641 tacaatcttt agcgaaacaa aaagctgcaa ctaccgaaaa ttatagacaa atgcttgaag
    44701 aaaaaaaggc ggctttaaag gaaaagggag taagcaaaga attcattgat gcattagaag
    44761 atgaaatgaa tgattacatc aaaactacaa atcaaggatt cgatagccaa atagctgcta
    44821 taacaaataa atatccacaa ttgattaacg aagtgagttt atcaaatggt caattattta
    44881 gcaaaacggc agctgctatg gacaatactg gtcagtatac aaaagttttt ctcgaaagta
    44941 atgaaaagat tttagcccaa gcgaagaaaa catcggatga aatagcagat aatgccgaaa
    45001 aaaatgcaga acaacttggt atggtagctg atgaggctac gcatgctgga tcaacttgga
    45061 atggattagt tttagacgaa aaaacaggaa aagtaaaaac taacgtacaa gaagtagtga
    45121 atgaagcaac gaaggatttc actaaatgga atgaacttaa acctgttgtt catgatgcga
    45181 aactaacaac gaacgcaaaa gatgtcattt ccatagcggc agtacaaaat ggttattggg
    45241 atgatatgga atggaaagaa aaagaagcat tattagaaga tgagtgttct aaaaatgtat
    45301 acaaggcttt agaaaatgct ggtaaatgga atgagttaga tattccttct aaagaagcaa
    45361 tcctaacttc aaatactcct gaagttatgg gtgaaactct catgaatttg ggactatggg
    45421 atacttacaa acttcaagtg aaagatttag atttgaatgc gtataaagta tacgatgcta
    45481 tcgatggatc agaagaaaaa ttaaatagtt gggctcaatt agataacccc acaaaagaat
    45541 tgttattaga taactcagat ttttctacaa aactttttaa ttccgaagaa atgtttaaac
    45601 gttggaatca gttatcatct aatgcaaagt ttctttcagc taataatact aaatttacag
    45661 aggttctttt atcatctgac agaatgtgga atcaatgggt aaaccttcct gataatgaga
    45721 aaagattact tgcagataac gaagatttag ctaccactgt tttatcttca gaagaaatat
    45781 acggaagatg gactcaatta ccagataatc aaaaatatat gttagctgac aatactgact
    45841 tagcaaacaa aatatttgct tcagaagaat catggaatgc atggaaagca attccagaca
    45901 tagttaaaaa cttgcttggt aataatattg atttactggc taaagtgaaa gatgggactg
    45961 taagtgtaga agaatataac aaagttatgc cacttcttaa aactctatat ggagataacg
    46021 ttaatttaaa agaggcaatc agtggggcta aaagctctat agagaattac aacaaaaata
    46081 tttttcctaa tgataaaact gcagtaggac acgatgaggc ttcacaagct gctaaagatg
    46141 catttgaagc gttcaacatc ttccaaacaa aaataccaga taaaattact aaaactgtat
    46201 cagctgactt tataggtcct atgcctaatg ctaaaggaac gaacttccat cctggcggag
    46261 cagctatggt aaacgatcaa aaaggaccta cttatgaaga gcttataacc ttgccaagcg
    46321 gagaagcttt tatacctaaa ggacgtaatg tcgttttaga cttaccaaga ggttcgaaag
    46381 tactgaacgc cactaaaact aaacgtctag tacctaaata tgctgatggt ataggaaaca
    46441 taacgacggt ttcatctacg ctaaacttag atgctttaat tttagctatt aacgagctaa
    46501 cgacggtatt gagaactcaa ctgatggcag aaacgactaa tgctaaagat actaaactat
    46561 cagatgaaac aaaagttgcc gatccgatta ttccgggcag tctttcagaa aaatcagatc
    46621 agtatctagg aattggagct caatggttaa ccaatctaat gaatggttgg aactcagcgg
    46681 ttcctcaata tatgaatagt gaaatggttt ttattacaaa ctatctcaat gcgctaaaac
    46741 ttcaaaacaa tcctaattat acgcaaggag tagcatggaa taagaactta ctgaatggat
    46801 ggaatagttt aactgggaca tttatttcta cgatcaattc attttgtaat caagcaatgg
    46861 tcacgcttag aaactacaac actcctatgt acaacaatgg ccgaacgtgg cagcaaaata
    46921 atcttaatgg ttggaattca ttgtatggat cattcatagc ccgtgtaaat cagcttggta
    46981 acgattcgat taacaacctt cgttctaaaa gtggtggttt ttacaatgca gggacattct
    47041 tgttgcaatc tttaataaac ggaatgaatt cgttaggtaa ttctctttct acaacaatga
    47101 acaatgtcgc taatacaatg gttggtggta tgggcaaagg ggttaatggc gtcatatcgg
    47161 gagttaacta tgtgcttaag gaagtcgagt caagtaagaa tatcggaaac tggccaattc
    47221 cacaatacgc taagggaact gatggacatc ctggtggact tgctatgatt aatgatcaaa
    47281 aaggcctagt tcacgaagaa tatgtacaga tgccagatgg acgtggtttt attgccaaag
    47341 gtagagacct tcttgttaat ttgcctaaag gtgctcaggt cttaaatgct tctttaacaa
    47401 agaaattaaa ggaacgttta aatattccac actacgaaaa aggtattggc aatttagata
    47461 ttgttgattt gttagatgat gaaaaaagaa tgttagaatt cttgactagc aaagttgact
    47521 tttcaggcat taatgaacca tggcttgata tgactaaatc aggaacgtca ttaatgtcta
    47581 aagctgcaaa tacaatgctt caatcaaaat taagtgaatt cttcactcat ggcaattttg
    47641 atggtgcagt aaatgccaat ggtgtttatc aatatttagt tgatgttgca cagaaagtaa
    47701 tgggtaagtt ccccggactt acagtaactt ctggatatcg agcaggagat gcttactatc
    47761 acggaaaacg gcaagctata gacttggctt atccaggtat atctggagat ccgagatata
    47821 cagcagcagc taattacgct tttgaaaaat tcccttcaaa aattgcgtat gtcattacga
    47881 atggacgtgt acgtgaccgc atgggattat ctggaacagg gtcaagcgga caatggacga
    47941 attggccaga tggcgatcac ttcgatcata ttcatttaaa cggttcgatg gggtctggcg
    48001 atatattcaa tggaggagtt ggaggaagtg gtgttgcacg ctggcgttct tatgtgtcta
    48061 aagcattgaa aatgaatgga ttaccagcta cagcagctta tataaatgcc tggatgtccc
    48121 aaatccaaac ggaatctggt ggtaatgaga aagcaatcgg cggcaatgat gggctcgctg
    48181 aaggcaatgc aacaggatta cttcaaacga aacccggaac ttttgcagct aacgcttttc
    48241 ctggtcacgg aaatattatg aacggatttg ataacatgtt agcagcaatc aattatgcta
    48301 agaaacgtta cggagttgca ggtatgttgc aagttatcgg gaaaggacat ggatatgcca
    48361 atggtggatt gattaccaaa gacggactat atcgagcggg agaaggaaat aaaccagaaa
    48421 tggttattcc attgacaaga aaaacaagag ctattgaatt gatgggtcaa gcattagctt
    48481 ttctttctgg cgatgacaag aaacgctcca acactacaaa tacagctgat aattcagcag
    48541 agcttgtaac tttgattaaa cagcaacaaa aacagcataa tgagttaatg atgattctta
    48601 gagcgattct tggaaaagat ttaagtctca agtcttctga cattgggcaa gctgctaatc
    48661 attatatggg ctctgatttg aataaacttc gatatacgaa tggaggtgtt tgataattgt
    48721 tttacaaatt acagttcaat caaaatggga agttgtttga tccgcaaaga aaagaaaaaa
    48781 ttgtatgtaa agaaatcaaa cgtcaagcac cagtgtatga agtgaattac gaagattttg
    48841 aagggacgaa cggtagcaga gaagctaatg ctagttttcg tccttttgaa ttagtgctga
    48901 cttttgatat cttttacaaa aataagcatg ataaagaact gctattaaca gagttctatg
    48961 agctaatttt tgtcggttat caatattaca tttcctatga tttaagccca ggaaaaagat
    49021 ttaaagtaaa tccaacaaat ttcgaaatta ctgaggaaga gaacgattat tctacgatag
    49081 aaataacctt tagtattcca tcagggagtg ctgaatccag cgcaaccact ttaacggatt
    49141 tcaatctaga ggaagaatgg caattctcgc aaggtctagt ggcggaagat tacaagtata
    49201 cgcatcagac tagtcacttc attatttaca atgctggaag ctttgaaatt gatccacgtg
    49261 aacattatct acggatcgca ttagaaggag aatcagaagg aaatgtgacg attttcaata
    49321 aaacaactgg cgatcgattt atttactatc catcactttc tacgaatctc ggacagacat
    49381 tagtcttgga tggcgtgatt ccaaaattga acggtgtaag ttgtggaatc aatacgaatc
    49441 acggtctgat caatttggtt gagggagtca atgaaatcga gatccaaaat attactcgcg
    49501 tgaaatcttc atgggatttc cgtttcttat ataagtaggt gattgagtga ctgagttaat
    49561 tattcgaaat tatgaacaaa ccaaagaaga aatccttgtc ggttatgaca agggttcttt
    49621 ttatgaaaac tggcaacaaa atgaaacgtg ggagattggc tttaccgtta ccagcaattc
    49681 gttgaatcaa gaagtatttg atttagtcga atacgagtct tctgttttct acaacggaca
    49741 ggaatttgtg atcaaagaaa tgactcgcaa agcacttgga caattgctga cgaaacaagt
    49801 agttgcgaca catatctatt acaccgttca agatggttat cagtacaaca cagtgacagg
    49861 tgcgaaatct attagccagt tactcacgca tgtatttagt gcagggagtc gcggctttac
    49921 atgggaagtc attgatccaa acaaaaaatt ccttaccgtt gaacaagaaa atttcggtaa
    49981 cgcgaattac ttgaagctga tcaatgagat tctatctgac tataatgcag tcgtgattcc
    50041 gaataataaa catctaactt tctatcctgc cagtgagtac ggccagcaga cggaagaaca
    50101 gattcgctat aaatacaata cagatgaagt gtcgtttgat attgatacgt attccttgaa
    50161 gacgcagatc aaaggctatg gaaaattgaa ggatggtgca aatactgaga atcctaaaga
    50221 tagtgactat atatttactc ccatcactta tacaagccct gaatcacaga agtggggaat
    50281 caggatacaa gatcctgtta aagacgaacg gtataccgta tcagggaaca tgctcgagcg
    50341 gttaaagaca gacttgcaag actatccaaa tatttcggga tccgtaacct tgaaatggaa
    50401 aatcagtccc aacaaaggcg atcacgtccc attcatttat gaacctttga atattaatac
    50461 gtacattcaa gtggtaggaa tcaagacgta tccagcgata ccaaataagc caccagaaat
    50521 cacattgagc aacacaaaga aaacaatgac gtcgatactc gctgaaatgg cgaagaaagg
    50581 agtgatttga tggggttatt aaaattaatc agtaaccgta tctctacgga atggaaagag
    50641 aaatttaata aaaacattga ctaccttaat gatcttgaaa agaaactgtc tgatcaagac
    50701 aaatcaatga acagtcgtat tgataatctc gtgcttcatt caggtggcga atcgccgaat
    50761 gaagtggttg atgctcgtgt aaataataag ggagaaacct ttcctacttt acacggcaga
    50821 ttggtagaac acgaaaccct gacagatgaa caaattagcg aactgaatac aaacatggat
    50881 agtcaaaaag agcaagttca acaattgaac aagtctgttc aacaaattat tggtggatac
    50941 aatgagccaa ttaacatcta tgtttctaaa gatggtagtg atattttggg tgatggatca
    51001 gaagaaaagc ccttcttaac cattcaaaca gccgtaaata atgttcctct aattacaacg
    51061 tctcaaatta ctatttgggt aggtagtggg gcttacttag aagatattat gattagaaat
    51121 ttaaatttta catcattttt aattcgacct atcgataatt ttgacactat tgatccatta
    51181 aaatcagatt tacctgttaa aatacgatcc atttgtttca ctgcttgcaa aggttattgt
    51241 caagttgctg gaatgcaaat tgtggataca gcaaacggag cagactatgg aatcagaaat
    51301 gagcaaagtg gctatatggc aatcaataga tgtaaattcg cagagaacac aaaaacactt
    51361 gcaagatata atgcagttta tgtcggcgga acatcaaaga ttaatatgta cggagacacg
    51421 acgttgatta accagaaagt ggcaatttac gctgtattga tgggtgaaat ttttgtcagt
    51481 gcgtttggtt caggaaacga cgtaggaatt ttgtgcgaga atggcactgt acgaggaact
    51541 gtatcaactt cttttgccac aaccccaaca aaaactactg ggtacggtct catcatcacg
    51601 aaaggcacgg tgttgcaata atggtataca aaacaaatga atcgatcatc atgattcaag
    51661 cagaagccac tagtccaaac aggacgaatg ttgttttttg gtcgcatgat cgaggaacag
    51721 ctaagcttcg aatgaaatta gttcggaaaa acggcattcc tcaaagctta cccgaaggca
    51781 caactgttcc gattcgcttg atgctcaaat ctgcaacggc agaaggtggt tatggaaaac
    51841 atgactatct cgccaccatt gaagatcgtg taaatggtat tgtgtccatt gtgctggaag
    51901 ataatatttt aggctatgtt ggaattgtcg aaggtagtgt ttatattgat ttcccaaacg
    51961 accgctcgtt agatacagct ggccgtttta cttttgacat caaacgcagt ccaatcgatg
    52021 atagtacacc agaattggaa gattattatt tcaatggttt cagtcagact attgataaaa
    52081 tcgaaaaaat tctagctgat ggaaagcaag agattgaaca gaaaattacg gaatctgaaa
    52141 cgcagattga tgggaaactg aaagaaacaa gcaacaaaat cacgaaagcc aatcaagatg
    52201 tcgcaactat caatacgaat attgataaag caaatgatcg tattgatcaa acgaaccagc
    52261 aaataagtga tctcggaaag ctgaaaaaga tgtactccaa cagcatcgat ttcgggaact
    52321 atgattatag tggaaatccg aatttgatgg ctaatataaa cgctgatagc ttctcgcaag
    52381 gtagtggtgc cttatctgtt gtagatgatg gtgacgaggt agtgattacg cttgatccaa
    52441 accataaatt agaaatattc aaagcgaaaa gtcaaccagc tctggtagtg gggaaaacat
    52501 ataccatgag tgtagaaatt atgttagaag atgatttcac tggagaccct agtaatatat
    52561 ctctaagata tattaaaatg cccagctggt taacagtact atatacgcct tatacattaa
    52621 ctaatactaa gggtgtatgg caaaaactaa ctgttaccgc taaaatgact actgcgattg
    52681 ataacgctga aagctggttt ataatgctac aaaataaaga cgctaataac agcctatccg
    52741 gcaaactacg tttgagacac gctaaactcg aagaaggctc aacagctaca ccattccaac
    52801 ctaacttatt agcagaacct tacaacatgt gtcgcgaata tcctaacgaa aatattgccg
    52861 atcctaaagt taagttccca atcgaatctg gcgaccacca aatatatcaa ggctacacag
    52921 aagaagagct tatgataggt caaacgtata ctatcacgct taaaggaaca aaacccgcaa
    52981 gtcaaacctt tgtagcgtat aatcattgga ctgctcgttt aggagaacta aagccggttg
    53041 atgggttgac agacgtatgg tctctaacat tcacaccaac gaatgttgtg gcgatgccta
    53101 aacttttccg tgtttatcag tatccacgat caacagtagg cgcatgccaa attgactggc
    53161 tcaagattga aaaaggcaac acccgaacgc ccaatattag tcagtttaaa tacttcggtg
    53221 aaggattgaa agacagcaac aatccgaatg attacagttg ggatgtcaca cctgaatata
    53281 ctgaaaaagg cttgaataat gctgttaatg tgtatgatcc tcagagagtt gaaggtttga
    53341 aaaactttgc cgatggtatt caaatagcag gagataaagt gatcagtgaa aatgattgca
    53401 ctgtttatac attaactaaa gacaacagtc aatcgtttat cgatgggtat gcaacattta
    53461 ttaaacacgg aaaagaagtt gttgtaaatg gtacagtaaa gttcaaaaaa gcttatgctt
    53521 ttggtgtacc acttgatgat gaagtcccag atgaatttat tgcaagaatt gttcatggca
    53581 tgcttacagg tcagtcagga acaaatagtg tatcaaaagc gatgtacgtg caaaaagact
    53641 taggaaaaat tatgacgaat agcgaatttg ccgcaaatga atggtttaca ttccacggta
    53701 attattgggt aggagtgaaa taaatgaaaa acatttggaa atacggacgt actggtggag
    53761 agtacgcagg aaaagtattg gacgacatgc ttgtatccgt tccttacacg gatcagccac
    53821 cgctcgaagg attacgtgct gatggcgaac cgctaacgat tgctgatcag atgtttgatc
    53881 ctaaactgaa ccaatggatt gttttagcga acacactgga tcacaacgat ttaaacaatc
    53941 tcaaagcgat gtacgaggca ctggaacacg agaacggcga tttaaaacag ctcaacgcca
    54001 aactcatgct aagcgatgta gcaattaaac aggaaaatac tgcattgaaa gaaaaagcgg
    54061 atagtttagc acaaatcaat tcaaaaatga tgcttgcttc gttacaaaat agcaaagaca
    54121 tttcagaaat taaagagcaa ctaaatccaa ctttaaaggg aggtgagtag tatgtttagt
    54181 tttagcgatg tgaaaatgat gtatgattgg ggctgtttta ctgacgatca agttcgacta
    54241 ttcgttccac tatgcattac agacgaagaa gcagataaaa tcattagcaa agaagagagc
    54301 gcatcttaag tgatgcgttt ttttgttgga aagttggtgg aacatgaaag aagaagcgct
    54361 ccaagacgtt gtggagagat tagtaagaat tgaaacaaaa ttagacaact acgaatcact
    54421 tagagaaaag gctgatagtg caaaagattt agcagataaa gcctattcag tagcactaaa
    54481 caatgcagaa gacatcaagg aaatgaagaa caataataaa tgggcttggg gctatatgat
    54541 tggcttaggc attacgatca ttggctattt cttgactaaa ttgtaaagga ggtgagaaga
    54601 aatgatttta ccagataagt attatcaagt cattaaatgg acagttttaa cagtattgcc
    54661 agctgcatct gctttagtag ccatgttagg gaaagcgtat ggatggaatg gaacagatat
    54721 gatagtgttg actatcaatg cagtagcaac atttttaggc gttatcactg gtgtgtcggc
    54781 ttataatttg aaaaaatagg aggaaacaaa tgaaaaagaa aattactatt actgcgatga
    54841 gcctattaac ggctcttttt ttattgccaa ttaatgggtt tgcctatact atcaacaatg
    54901 aatttaattt gggcgcaaat gaaggtagct cacaaatagc aaataatcag tacattttac
    54961 tgcatgaaac ggctaatgaa acagcaacag gacgcaatga agcgcagtat atgcaacgtt
    55021 catggactag cgcttatact gcttatattg tgggagacgg cggaattgtt tatcaagtcg
    55081 gtcaacctgg ttatgtacag tacggtgctg gttcgtatgc taatgccaac agtcctgtgc
    55141 agattgagtt acaacacaca catgataaag caacgtttga gaaaaactac aaggcatacg
    55201 ttgaattggc tagagattca gcaatgaaat atggtattcc attaacatta gacacgcctt
    55261 ataaccaacc aggaatcaaa tcacatttat gggtaacaca aaatatctgg ggagatcata
    55321 ctgatccata cggttatctt tctgaaatgg gcgtaagtaa agaaaaatta gc
//
LOCUS       DAPBCF010000015        54691 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.015, whole genome shotgun sequence.
ACCESSION   DAPBCF010000015 DAPBCF010000000
VERSION     DAPBCF010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 54691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.015"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            319..627
                     /gene="rpsJ"
                     /locus_tag="RD508_001105"
     CDS             319..627
                     /gene="rpsJ"
                     /locus_tag="RD508_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDT7735716.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            658..1287
                     /gene="rplC"
                     /locus_tag="RD508_001106"
     CDS             658..1287
                     /gene="rplC"
                     /locus_tag="RD508_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDT7735717.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            1315..1938
                     /gene="rplD"
                     /locus_tag="RD508_001107"
     CDS             1315..1938
                     /gene="rplD"
                     /locus_tag="RD508_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDT7735718.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            1938..2228
                     /gene="rplW"
                     /locus_tag="RD508_001108"
     CDS             1938..2228
                     /gene="rplW"
                     /locus_tag="RD508_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDT7735719.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            2267..3100
                     /gene="rplB"
                     /locus_tag="RD508_001109"
     CDS             2267..3100
                     /gene="rplB"
                     /locus_tag="RD508_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDT7735720.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            3143..3421
                     /gene="rpsS"
                     /locus_tag="RD508_001110"
     CDS             3143..3421
                     /gene="rpsS"
                     /locus_tag="RD508_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDT7735721.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            3444..3791
                     /gene="rplV"
                     /locus_tag="RD508_001111"
     CDS             3444..3791
                     /gene="rplV"
                     /locus_tag="RD508_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDT7735722.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            3805..4461
                     /gene="rpsC"
                     /locus_tag="RD508_001112"
     CDS             3805..4461
                     /gene="rpsC"
                     /locus_tag="RD508_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDT7735723.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            4464..4898
                     /gene="rplP"
                     /locus_tag="RD508_001113"
     CDS             4464..4898
                     /gene="rplP"
                     /locus_tag="RD508_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDT7735724.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            4888..5076
                     /gene="rpmC"
                     /locus_tag="RD508_001114"
     CDS             4888..5076
                     /gene="rpmC"
                     /locus_tag="RD508_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDT7735725.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            5101..5367
                     /gene="rpsQ"
                     /locus_tag="RD508_001115"
     CDS             5101..5367
                     /gene="rpsQ"
                     /locus_tag="RD508_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDT7735726.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            5425..5793
                     /gene="rplN"
                     /locus_tag="RD508_001116"
     CDS             5425..5793
                     /gene="rplN"
                     /locus_tag="RD508_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDT7735727.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            5830..6138
                     /gene="rplX"
                     /locus_tag="RD508_001117"
     CDS             5830..6138
                     /gene="rplX"
                     /locus_tag="RD508_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDT7735728.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            6166..6705
                     /gene="rplE"
                     /locus_tag="RD508_001118"
     CDS             6166..6705
                     /gene="rplE"
                     /locus_tag="RD508_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDT7735729.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            6724..6909
                     /locus_tag="RD508_001119"
     CDS             6724..6909
                     /locus_tag="RD508_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HDT7735730.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            6945..7343
                     /gene="rpsH"
                     /locus_tag="RD508_001120"
     CDS             6945..7343
                     /gene="rpsH"
                     /locus_tag="RD508_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDT7735731.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            7375..7911
                     /gene="rplF"
                     /locus_tag="RD508_001121"
     CDS             7375..7911
                     /gene="rplF"
                     /locus_tag="RD508_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDT7735732.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            8072..8428
                     /gene="rplR"
                     /locus_tag="RD508_001122"
     CDS             8072..8428
                     /gene="rplR"
                     /locus_tag="RD508_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDT7735733.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            8449..8949
                     /gene="rpsE"
                     /locus_tag="RD508_001123"
     CDS             8449..8949
                     /gene="rpsE"
                     /locus_tag="RD508_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDT7735734.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            8964..9143
                     /gene="rpmD"
                     /locus_tag="RD508_001124"
     CDS             8964..9143
                     /gene="rpmD"
                     /locus_tag="RD508_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDT7735735.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            9187..9627
                     /gene="rplO"
                     /locus_tag="RD508_001125"
     CDS             9187..9627
                     /gene="rplO"
                     /locus_tag="RD508_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDT7735736.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            9627..10922
                     /gene="secY"
                     /locus_tag="RD508_001126"
     CDS             9627..10922
                     /gene="secY"
                     /locus_tag="RD508_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDT7735737.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            10984..11631
                     /locus_tag="RD508_001127"
     CDS             10984..11631
                     /locus_tag="RD508_001127"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDT7735738.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            11822..12040
                     /gene="infA"
                     /locus_tag="RD508_001128"
     CDS             11822..12040
                     /gene="infA"
                     /locus_tag="RD508_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDT7735739.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            12073..12189
                     /gene="rpmJ"
                     /locus_tag="RD508_001129"
     CDS             12073..12189
                     /gene="rpmJ"
                     /locus_tag="RD508_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDT7735740.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            12207..12572
                     /gene="rpsM"
                     /locus_tag="RD508_001130"
     CDS             12207..12572
                     /gene="rpsM"
                     /locus_tag="RD508_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDT7735741.1"
                     /translation="MARIAGVDIPRDKHVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            12600..12989
                     /gene="rpsK"
                     /locus_tag="RD508_001131"
     CDS             12600..12989
                     /gene="rpsK"
                     /locus_tag="RD508_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDT7735742.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            13069..14007
                     /locus_tag="RD508_001132"
     CDS             13069..14007
                     /locus_tag="RD508_001132"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDT7735743.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            14035..14415
                     /gene="rplQ"
                     /locus_tag="RD508_001133"
     CDS             14035..14415
                     /gene="rplQ"
                     /locus_tag="RD508_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDT7735744.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            14687..15526
                     /locus_tag="RD508_001134"
     CDS             14687..15526
                     /locus_tag="RD508_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7735745.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            15502..16371
                     /locus_tag="RD508_001135"
     CDS             15502..16371
                     /locus_tag="RD508_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7735746.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            16361..17158
                     /locus_tag="RD508_001136"
     CDS             16361..17158
                     /locus_tag="RD508_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDT7735747.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            17361..18107
                     /gene="truA"
                     /locus_tag="RD508_001137"
     CDS             17361..18107
                     /gene="truA"
                     /locus_tag="RD508_001137"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDT7735748.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(18562..21231)
                     /locus_tag="RD508_001138"
     CDS             complement(18562..21231)
                     /locus_tag="RD508_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HDT7735749.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(21469..21657)
                     /locus_tag="RD508_001139"
     CDS             complement(21469..21657)
                     /locus_tag="RD508_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDT7735750.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            21927..22289
                     /locus_tag="RD508_001140"
     CDS             21927..22289
                     /locus_tag="RD508_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7735751.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            22341..24023
                     /locus_tag="RD508_001141"
     CDS             22341..24023
                     /locus_tag="RD508_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HDT7735752.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            24140..26176
                     /gene="recG"
                     /locus_tag="RD508_001142"
     CDS             24140..26176
                     /gene="recG"
                     /locus_tag="RD508_001142"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDT7735753.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            26225..27226
                     /gene="plsX"
                     /locus_tag="RD508_001143"
     CDS             26225..27226
                     /gene="plsX"
                     /locus_tag="RD508_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDT7735754.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            27348..27590
                     /gene="acpP"
                     /locus_tag="RD508_001144"
     CDS             27348..27590
                     /gene="acpP"
                     /locus_tag="RD508_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDT7735755.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            27858..28862
                     /locus_tag="RD508_001145"
     CDS             27858..28862
                     /locus_tag="RD508_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7735756.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            28863..29807
                     /locus_tag="RD508_001146"
     CDS             28863..29807
                     /locus_tag="RD508_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7735757.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            29807..30769
                     /locus_tag="RD508_001147"
     CDS             29807..30769
                     /locus_tag="RD508_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7735758.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            30796..31710
                     /locus_tag="RD508_001148"
     CDS             30796..31710
                     /locus_tag="RD508_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7735759.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            31736..33517
                     /locus_tag="RD508_001149"
     CDS             31736..33517
                     /locus_tag="RD508_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7735760.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            33865..34551
                     /locus_tag="RD508_001150"
     CDS             33865..34551
                     /locus_tag="RD508_001150"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDT7735761.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            34571..38152
                     /gene="smc"
                     /locus_tag="RD508_001151"
     CDS             34571..38152
                     /gene="smc"
                     /locus_tag="RD508_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HDT7735762.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            38161..38970
                     /locus_tag="RD508_001152"
     CDS             38161..38970
                     /locus_tag="RD508_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7735763.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            38981..39979
                     /gene="ftsY"
                     /locus_tag="RD508_001153"
     CDS             38981..39979
                     /gene="ftsY"
                     /locus_tag="RD508_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDT7735764.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            40166..42433
                     /gene="gshAB"
                     /locus_tag="RD508_001154"
     CDS             40166..42433
                     /gene="gshAB"
                     /locus_tag="RD508_001154"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HDT7735765.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(42522..42974)
                     /locus_tag="RD508_001155"
     CDS             complement(42522..42974)
                     /locus_tag="RD508_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HDT7735766.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            43124..44074
                     /locus_tag="RD508_001156"
     CDS             43124..44074
                     /locus_tag="RD508_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDT7735767.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            44067..45026
                     /locus_tag="RD508_001157"
     CDS             44067..45026
                     /locus_tag="RD508_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDT7735768.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            45023..45778
                     /locus_tag="RD508_001158"
     CDS             45023..45778
                     /locus_tag="RD508_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7735769.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            45801..46754
                     /locus_tag="RD508_001159"
     CDS             45801..46754
                     /locus_tag="RD508_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7735770.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(47398..47694)
                     /locus_tag="RD508_001160"
     CDS             complement(47398..47694)
                     /locus_tag="RD508_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HDT7735771.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            48049..48405
                     /locus_tag="RD508_001161"
     CDS             48049..48405
                     /locus_tag="RD508_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDT7735772.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            48415..49314
                     /locus_tag="RD508_001162"
     CDS             48415..49314
                     /locus_tag="RD508_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HDT7735773.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            49830..50561
                     /locus_tag="RD508_001163"
     CDS             49830..50561
                     /locus_tag="RD508_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HDT7735774.1"
                     /translation="MMKKEIVLTAAIMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            50706..52733
                     /locus_tag="RD508_001164"
     CDS             50706..52733
                     /locus_tag="RD508_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HDT7735775.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            52841..53938
                     /locus_tag="RD508_001165"
     CDS             52841..53938
                     /locus_tag="RD508_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HDT7735776.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            54245..>54691
                     /locus_tag="RD508_001166"
     CDS             54245..>54691
                     /locus_tag="RD508_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7735777.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        18278 a         9663 c        11734 g        15016 t
ORIGIN      
        1 tttattgcag gatcaggaaa aaagacagga gtattataaa tagaagaaac acgaaataaa
       61 agagtcagta ttttctaaat gaaactttat gaaaacaaaa tgttttttac aagaaaaagc
      121 cttgctttgt gagtttatat atattataat gacaaaggtg cgtttacttt agtgaattgc
      181 acagacgtaa tcagaatgat ttcgtcggct aagaaacgag aggttgcgac acgcccggac
      241 gctttgccac gaacgagcgt gacggaaatt ttcgtggagc tatgtctact tttcaaaata
      301 ggcgaaggag ggaacaagat ggcaaaacaa aaaattcgta tccgtttaaa agcgtatgaa
      361 caccgtattt tagatcaatc agcggataaa atcgtggaaa ctgcaaaaag aactggagct
      421 agcgtgtctg gtccaattcc attaccaact gaacgcagtc tttacacaat catccgtgcg
      481 actcataaat acaaagattc acgcgaacaa ttcgaaatgc gtacacacaa acgtcttatc
      541 gacattgtga acccaacacc aaaaactgtt gatgctttga tgaagctaga cttaccatct
      601 ggtgtaaaca tcgaaatcaa attataaaac taaaacaaaa ataatggagg tgtactcatg
      661 accaaaggaa tcttagggaa aaaagtggga atgacacaaa tcttcactga atctggtgaa
      721 ttaattccag taactgttgt agaagctact ccaaacgtag tactacaagt gaaaacaatg
      781 gaaacggatg gctacgaagc tattcaagtt ggttaccaag atatgcgtga agttttatca
      841 aacaaacctg cgaaaggtca tgttgcaaaa gcaaacacgg ctcctaagcg cttcattcgt
      901 gaattcaaaa atgttgagct aggagaatat gaagtaggaa aagaaattac agtagatgtt
      961 ttccaagcag gagacattat tgatgtaaca ggtactacga aaggtaaagg attccaaggg
     1021 gttatcaaac gccacggaca aagccgcgga ccaatggctc acggttctcg ttaccatcgt
     1081 cgtcctgggt caatgggtcc agttgcacct aaccgtgtat ttaaaaacaa acgtcttgct
     1141 ggccgtatgg gtggcaaccg cgtaactatc caaaacttgg aagttgtacg tgtcgatgca
     1201 gaaagaaatg ttatcttgat caaaggtaat gttcctggag ctaaaaaatc tttaattact
     1261 atcaaatcag ctgtgaaagc taaataattg taggaagaaa ggaggaacta aggaatgccg
     1321 aatgtagcat tattcaaaca agatggaagc caaaacggtg aaatcacact taacgaagaa
     1381 atcttcggaa ttgaacctaa tgaaagtgtt gtttacgatg caatcgtaat gcaacgtgcg
     1441 tcattaagac aaggaacaca cgcggttaaa aaccgtagcg ctgttcgcgg cggcggacgt
     1501 aaaccatggc gtcaaaaagg aacaggtcgt gcacgtcaag gatctatccg ctcaccacaa
     1561 tggcgtggag gtggcgtagt ctttggacca acaccacgtt cttacagcta caaacttcct
     1621 aaaaaagttc gtcgtttagc aatgaaatct gtattgtcag aaaaagttgc tgaaaacaac
     1681 ttggtagcaa tcgaaggctt gaacttcgac gcaccaaaaa caaaagaatt caaacaagtt
     1741 cttgctaact tatctatcga ctctaaagta ttggttgttc tagaaaaagg taacgacttt
     1801 gctgctttat cagcacgtaa cttaccaaac gtttctgtag taacttctga taatgtgagt
     1861 gtgctagacg ttgtatcaaa tacaaaagtg ttagcaacac aaactgctct tactcaaatt
     1921 gaggaggtgc ttgcataatg aacttactag acgtaatcaa acgcccagtg atcactgaaa
     1981 aatcaatgct tgccatggat gacaagaaat acacttttga agtggacact cgcgcaaaca
     2041 aaactttagt aaaacaagcg gtagaagctg cttttgacgt taaagtcaaa aacgtgaaca
     2101 tcgtgaacgt acgtgcgaaa ttcaaacgta tgggcaaata tgcaggatat acaaaaaaac
     2161 gtcgcaaagc gatcgttaca ttgactgaag attcaaaaga aatccaatta ttcgaagctg
     2221 ctgaataagc actaatagat aactcattaa attaggaggg aaaaacgtgg cgattaaaaa
     2281 gtacaaacct acctcaaatg gtcgtcgtaa catgacaggt tctgattttg ctgaaatcac
     2341 aacatcaaca cctgaaaaat cattgttaca accattgaaa aaccatgctg gacgtaacaa
     2401 caacggccgc atcactgtac gtcatcaagg tggcggacac aaacgccaat atcgcgtgat
     2461 cgacttcaaa cgtaacaaag ataacgttgt tgcaactgtt caaacgatcg aatatgatcc
     2521 aaaccgttca gctaacatcg cgttagtaca ctatgaagat ggagtgaaag cttacatctt
     2581 agcacctaaa ggactagaag tgggtatgaa acttgtttca ggtccagaag cagatatcaa
     2641 agtcggaaat gctcttccat tagaaaacat tccagttggt actgttatcc acaacattga
     2701 aatgaaacct ggtaaaggtg gacaattgat ccgttctgct ggtacaagtg ctcaagtact
     2761 tggtaaagaa ggcaaatacg tattgatccg cttgaactct ggtgaagttc gtatgatctt
     2821 agctgcatgc cgtgctacaa tcggttctgt aggtaacgaa caacacgaat taatcaacat
     2881 cggtaaagct ggacgctctc gttggatgcg taaacgccca actgtacgtg gtagcgtaat
     2941 gaaccctaat gatcacccac acggtggtgg tgaaggtaaa gctcctatcg gacgtaaagc
     3001 accagtttct ccttggggtc aaccagctct tggttacaaa actcgtaaca aaaaagctaa
     3061 atcagacaaa cttattgttc gtcgtcgcaa aaataaataa ttactttgac catgtgtcgc
     3121 acattttgag aggaggttca ccatgggtcg tagtttaaag aaaggacctt ttgtcgatga
     3181 gcatttaatg aaaaaagttg aagctcaagc aggggttgaa aagaaaaaag ttatcaaaac
     3241 ttggtcacgc cgttcaacag ttttcccaag ttttgttgga tataccatcg cagtttatga
     3301 tggacgtaaa catgtaccag tttacatcca agaagacatg gtaggacaca aattaggtga
     3361 atttgcacct acaagaactt atcgtggaca tgctgctgac gataagaaaa cgaaacgcta
     3421 atttgagggg aggataaatc caaatggcag aacaaatcac atcagctaaa gcaactgcaa
     3481 aaacagttcg cacttcacct cgaaaagccc gtttagtaat tgaccttatc agaggtaaaa
     3541 gtgtcgcaga tgcaatttca atcttgaaat tcacaccaaa caaatctgct ggaatcattg
     3601 aaaaagtatt gatgtcagca gttgcgaatg cagaaaataa ctttgactta gatgttgaaa
     3661 acttggtagt aagcgaagct tttgttaacg aaggacctac aatgaaacgt ttccgtcctc
     3721 gtgcaaaagg atcagcttct ccaatcaaca aacgtacaag tcatatcacg gtagtcgtat
     3781 cagaaaaata aggagggata atcagtgggt caaaaagtac atccaattgg aatgcgtgta
     3841 ggcatcatcc gcgactggga tgctaaatgg tatgctgaaa aagagtatgc tgagttctta
     3901 cacgaagatt taagaatccg taaatttatt tcaactaaac ttgctgatgc tgctgtatca
     3961 acagttgaaa tcgaacgcgc aacaggtcgc gtaaacattt caattcacac agctaaacca
     4021 ggtatggtta ttggtaaagg cggttctgaa gtcgaaagcc taagaaaaga attaaacaaa
     4081 ttaactggta aaagaatcca tatcaatatc gtggaaatca aaaaaccaga tctagatgca
     4141 aaattagtag gtgaaggaat cgcacgtcaa ttagaaaacc gtgttgcttt ccgtcgcgct
     4201 caaaaacaag ccatccaacg ctcaatgcgt gctggcgctc aagggatcaa aactcaagta
     4261 tctggtcgtc taaacggagc agatatcgct cgttcagaag gatactcaga aggaactgtt
     4321 cctcttcata ctttacgtgc ggacattgat tacgcatggg aagaagcaga tacaacatac
     4381 ggaaaactag gagttaaagt gtggatctat cgtggagaaa ttcttccaac taaaaaaaac
     4441 actgagaaag gagggaaata atcatgttag tacctaaacg tgtaaaacac cgtcgtgaat
     4501 tccgcggaaa aatgcgcggg gaagctaaag gcggaaaaga agtagcattc ggtgaatacg
     4561 gtttgcaagc tgttgattca cattggatca caaaccgcca aatcgaagct gctcgtatcg
     4621 caatgactcg ttacatgaaa cgtggtggga aagtatggat taaaattttc cctcacaaat
     4681 cttatactgc caaagcaatt ggggtacgta tgggttctgg taaaggggca cctgaaggat
     4741 gggttgcacc agtaaaacgt ggtaaaatca tgtttgaaat cgcaggcgtt cctgaagaag
     4801 tagctcgtga agcgttacgt ctagcttctc acaaattacc aatgaaaact aagatcgtaa
     4861 aacgtgagga aatgggtggt gaatcgaatg aaggttaaag aaatcagaga attaaccact
     4921 gccgaaatgc ttgatcaaga aaaacaatta aaagaagaat tgtttaatct tagattccaa
     4981 ttagcaacag gtcaattaga aaacactgca cgtattaaag aagtacgtaa atcgattgca
     5041 cgcatcaaaa ctgtgttgcg tgaacaagct aagtaattat ggaaggaggc cattaagcgt
     5101 atgactgaag gaagaaatca acgcaaagtt tatcaaggtc gcgtggtttc agacaaaatg
     5161 gataaaacaa ttaccgttgc tgtcgaaaca aagaaaaacc accctatcta tggcaaacgc
     5221 atgaactatt ctaagaaata caaagtgcat gatgaaaaca acacagcaaa agttggcgac
     5281 atcgtgagaa ttatggaaac tcgtccatta tcagctacaa aacgtttccg tttgttggaa
     5341 gtagtcgaag aagcagttat tatctaataa cacgagattt tcctatatag attgaatgca
     5401 aaatctgaaa ggaggataca caacgtgatc caagcagaaa gtcgtttaaa agtcgctgat
     5461 aactcaggcg cacgtgaaat tttgacgatc aaagtccttg gtggatctgg tcgtaaaact
     5521 gctaacatcg gtgatgtgat cgttgctacg gttaaacaag caacgccagg tggggttgtc
     5581 aaaaaaggtg acgtcgttaa agccgttatc gttcgaacaa aatcaggagc tcgtcgtaca
     5641 gacggttcat atattaaatt tgatgaaaat gctgcagtga ttattcgtga tgataaaagc
     5701 cctcgtggaa cacgtatctt tgggccagtt gcacgtgaac tacgtgaaaa caacttcatg
     5761 aagatcgttt cactagcacc agaagtttta taatcttgag acacttatca aaggaggtgc
     5821 gaaacagtta tgtttgttaa aaaaggcgat aaagttaaag ttatcactgg aaaagacaaa
     5881 aacaaagaag gcgttgtact agcagcgttc ccgaaaaaag ataaagttat tgtcgaaggt
     5941 gtaaatgtcg ttaaaaaaca ccaaaaacct tctcaagctg ctcctcaagg tggaattgtt
     6001 gagatggaag cgccaattca tgtttctaac gtgatggtgg ttgactctac tggtgtagct
     6061 ggccgagttg gctacaaaga agtagacggc aaaaaagtcc gtgtttctaa aaaaaccggt
     6121 gaagttttag ataaataaaa gtttaaggaa ggagggtctt actgaatgaa ccgcctaaaa
     6181 gaaaaatatc ttaaagaagt aactccatca ttgatggaaa aatttaacta tagctctgtt
     6241 atgcaaacac ctaaagttga aaaaatcgtc atcaacatgg gtgttggtga tgcggtatca
     6301 aacgctaaaa acttagataa agcagttgaa gaattaactt tgatcactgg tcaaaaacca
     6361 atgattacaa aagctaaaaa atcaatcgct ggattccgtt tacgtgaagg aatgccaatt
     6421 ggtgcaaaag ttacattgcg cggagaaaga atgtacgaat tcttagacaa attggtttct
     6481 gtttcactac cacgtgtacg tgacttccat ggtgtaagta aaaaagcctt tgacggtcgt
     6541 ggaaactata ctttaggtat taaagaacaa ttgatcttcc cagaagtaga ttatgattta
     6601 gtagataaag tacgtggtat ggacatcgtt attgtaacaa cagcaaactc tgatgaagaa
     6661 tctcgtgagt tgttgacaca attaggcatg ccattccaaa aataattaaa ggaggcgaac
     6721 tacgtggcta aaaaatcaat gattgctaaa aacaaacgtc ctgcaaaatt ttcaacacaa
     6781 gcttatactc gttgcgaacg ttgcggacgt ccacattcag tttatcgtaa gttccatctt
     6841 tgccgtattt gcttccgcga acttgcctat aaaggtcaaa ttcccggcgt gaagaaagct
     6901 agctggtaaa aagtaaattc gcataagaag gaggtaaaag atcaatggtc atgacagatc
     6961 caattgcaga ttttctaact cgtatccgta acgcaaacat ggttaaacat gagtctttag
     7021 aagtacctgc atcaaaaatt aaacgtgaca tcgctgaaat cttgaaacgt gaaggtttcg
     7081 ttcgtgatgt tgaatacatc gaagatgaca aacaaggcgt gatccgtgtt ttcctaaaat
     7141 ttggtaaaaa cggcgaacgt gttatcacaa acttaaaacg tatctctaaa ccaggtttgc
     7201 gtgcttatgt caaagctgac gaagtaccaa aagtattgaa cggtttaggt atcgcaatca
     7261 tttcgacttc tgaaggtgtt gtcactgata aagaagctcg tgaaaaaaat atcggcggcg
     7321 aagttatcgc ttacgtatgg taatcaagta gaatctacaa ggaggtgtct ttaagtgagc
     7381 cgtatcggaa ataaagtcgt tgttatccct gaaggagtaa cagttactca agacggaaac
     7441 aacgttacag ttaaaggacc aaaaggtgaa ttgactcgta ctttttcagc agatatcaaa
     7501 atgaatatcg aaggaaacga agtaactttc actcgtccaa acgacagtaa agaaatgaaa
     7561 acaattcatg gaacaactcg tgcgaacttc aacaacatgg ttgtaggtgt cagcgaaggt
     7621 ttccaaaaag cgttagaact aatcggggtt gggtaccgtg cacaattaca aggatcaaaa
     7681 cttgtattga acgttggtta ctcacatcca gtagaaatca caccaccagc tggagtaact
     7741 gttgaagtac cagctaacac acaagtaatt gttaaaggtg cgaacaaaga agaagttggc
     7801 gaattagctg caaacattcg tggaactcgt cctccagaac cttataaagg taaaggtatt
     7861 cgttatgttg gcgaatatgt acgccgtaaa gaaggtaaaa ctggtaaata atcgtttaga
     7921 aaaattgcat agaagccagc agcaggaaaa aggcatttgg ctgaagttta ccttcaaaaa
     7981 aatacatttt tacttgtgcc gcagcttcta tttttcgaaa cgtatttact gcttgaaata
     8041 gtagtacaat aaaaataaag aggtgacaat tgtgattaca aaaccagata agaacaaaac
     8101 acgtcaaaag agacatcgtc gtgtacgtaa caatatctct ggtactgctg agcgcccacg
     8161 cttgaacgtt tttcgttcta acaaaaacat ctacgctcaa attattgatg acgtagcggg
     8221 tgtaacgcta gcaagtgcct ctaccttgga taaagaaatt tcaggtggaa caaaaacaga
     8281 agcagcacaa gctgtcggta aactagttgc tgaacgtgca gctgaaaaag gcattaaagt
     8341 agtagtcttt gaccgtggtg gataccttta ccatggccgt gtgcaagctt tagctgaagc
     8401 tgctcgcgaa aatggactag aattttagaa gaaggaggaa taccattcat ggtttatatc
     8461 gatccaaaac atttggaatt agaagaccgc gttgttgcaa ttaaccgtgt aacaaaagtt
     8521 gttaaaggtg gacgtcgtct acgttttgct gctttagttg ttgtcggtga caaaaacgga
     8581 cacgtagggt ttggtacagg taaagctcaa gaagttcctg aagcaatccg taaagcaatt
     8641 gaagatgcga agaaaaactt agttgaagta cctatggttg gttcaacaat cccacacgaa
     8701 gtaatcggtg cttttagtgg tggtagaatc ctaatgaaac ctgctgtaga aggttctggg
     8761 gttgctgctg gtggaccagt tcgtgccgta ttagaattag ctggggtagc agatatcact
     8821 tctaaatctt taggctcaaa tacaccaatc aacgttgttc gcgcaacagt tgaaggtttg
     8881 aaacaattga aacgtgcaga agaagttgca gaacttcgcg gcaaatcagt tgaagaatta
     8941 atcggataag gaggacaaca ataatggctg aattaaaagt tactttaaaa cgcagtatta
     9001 tcggacgtcc tcaaaaccaa cgcgatacag ttaaagcgtt aggtcttaca aagattaaca
     9061 gttcagtggt taagccttct aatgaagcaa ttaaaggcat gatcaatact gtttctcacc
     9121 tagtggacgt tgaagaaatt taatttagaa aaatcataac tagaacatta aggaggtgcc
     9181 aaacctatga aacttcatga attaaaacct gctgaaggtt cacgccaagt acgtaaccgt
     9241 gttggtcgtg gtacttcatc tggtaacgga aaaactgccg gacgcggaca aaaaggacaa
     9301 aaagctcgtt caggcggcgg tgtgcgttta ggatttgaag ggggacaaac accattgttc
     9361 cgtcgtttac caaaacgagg attcacaaac gtgaaccgta aagactatgc agtcattaat
     9421 cttgatgtat tgaaccgctt tgaagacgga gctgaagtaa ctcctgttgc tttagttgaa
     9481 gctggaatcg tgaaaaacga aaaagctgga atcaaagtat tagctaatgg ggaactaaac
     9541 aagaaattaa ctgtgaaagc agcaaaattc tctaaagcag ctcaagaagc aattgaagcg
     9601 gctggtggat caatcgaggt gatctaatgt ttagactatt aaaagatgct tttaaagtaa
     9661 aagacattag atcgaaaatc ctatttactg tatttgtgtt gtttgtattt cgcctaggtg
     9721 cacatattac tgtaccaggc gtaaatgctg cttcattgca aaacctttct tctttgccat
     9781 ttttcaacat gttgaacttg gtaagtggta gtgcgatgca aaacttttcc attttctcaa
     9841 tgggggtttc accatacatt actgcttcta tcgtcattca gcttcttcaa atggacatcg
     9901 tgcctcgatt tgttgaatgg tcgaaacaag gggaagttgg tcgtaaaaaa ctgaatcaag
     9961 cgactcgata tctgacatta gtattggcat ttatccaatc tgtcggtatc actgctggat
    10021 tcaatcaata cgctcaatta ggtttcgtga ataatcctaa cgtagcaact tacgtaacga
    10081 tcggtttgat tctaacagcc ggtacgatgt ttgttacttg gctaggagaa cagatcacag
    10141 aaaaaggtat cggaaatggc gtatcaatga tcatttttgc aggtatcatt tctagattgc
    10201 ctgaaagtat cagagaaatt tatgaagatt actttataaa tattgatcct tcagacatat
    10261 ggaaatctgc tatttttgtg gccattttac tagtagcggt cttgttgatc gtgacattcg
    10321 taacattttt ccaacaagct gaacgcaaga tcccgatcca atatacgaaa cgcgtagctg
    10381 gcgcgcctac aagcagctat ctgccgttga aagtaaatgc agctggagtt attccagtta
    10441 tctttgctag ttcgtttatt gctacgccaa atgctgtttt acaagcattg agcggtagat
    10501 tcggttctga aaactggtac aaagtgatga tggagatctt taactataat acagcacctg
    10561 gtgctacgat ttatacgatt ctgatcgttg ccttcacttt cttctacgcc tttgttcaag
    10621 taaaccctga gaaattagcg gaaaacttgc aaaagcaagg aagttatata ccaagcgtac
    10681 gccctggtaa ggggactgaa gagtatgtct caagattact gatgcgttta agtacagttg
    10741 gtgcagtctt ccttggttta gtggcattgc ttccaatcat tgctcaaatg gtttgggatc
    10801 ttccacaatc aatcggatta ggcggtacaa gcttactgat cgttatcggt gtagctttag
    10861 aaactgcgaa acagttagaa ggcttaatgc tgaaacgtaa atatgttgga ttcattgagt
    10921 aagaaagcgt gttgaggttt cccctcaaca cacgttctca cacatttatt aggagggaaa
    10981 acaatgaacc tcattttaat ggggctgcca ggcgcaggta aaggaacaca agctgaaaaa
    11041 atcattgatg cttatggtat tccgcacatc tcaacaggag atatgttccg cgcagcgatg
    11101 caaaacgaaa cagctcttgg cctggaagca aagtcttata tggataaagg tgcattagtt
    11161 cctgatgaag taacaaatgg aatcgtgaaa gagcgactag ctgaaccaga tacagagaaa
    11221 ggcttcttat tagatggctt tccacgtacg ctagatcaag caaaagctct ggacgcaatg
    11281 ctaaaagatt tgaataaaaa aattgatgct gtcatcgata tccatgttgg tgaagaaatc
    11341 ttggtcgaac gtctagccgg ccgatttatc tgcagcaatt gtggagcaac ttaccataaa
    11401 attttcaacc ctacaaaagt tgaagacaca tgtgatcgtt gcggtgggca tgaattctat
    11461 caaagagaag atgataaacc tgagacggtt aaaaatcgtc tggctatcaa catcaaaaat
    11521 agtgaaccaa tcttggctta ttataaagaa caaggtttgc taaacactat tgatggtgct
    11581 cgtgaaatcg atgctgtatt tgcagatgta caaaaaatca ttgaaaaata gcacgattgc
    11641 ccgtagccga cttgcattat gcagttactc ttgtcaagtt caataaatta tgatagaata
    11701 tgtcagtccg acttctagag aatcctctag atgatccatt ttgagaattt tgaggtggga
    11761 actgcagttt ccgccatttt atcgtgtgaa aatgcgaaac aagtacaagg aggtactgtg
    11821 cgtggcaaaa gaagatatga ttgaagtcga aggtacagtc gtcgaaactt tgccgaatgc
    11881 aatgtttaaa gttgaactag aaaacggaca ccaagttctt gctactgttt caggtaaaat
    11941 tcgtatgcat tacatccgta tcttacctgg tgacaaagta acggttgaat tgtctccata
    12001 cgatcttaac cgtggccgta ttacttatcg ctttaaataa ttgtactccg taaaactaca
    12061 ggaggtatta tcatgaaagt aagaccatca gtaaaaccaa tgtgcgaaca ttgtaaagta
    12121 attcgtcgta aaggacgcgt tatggtgatt tgcccagcaa atccaaaaca taaacaacgt
    12181 caaggataat tggaggtgct ataaatatgg ctcgtattgc aggagtagat attcctcgtg
    12241 ataaacatgt agtagtttca cttacttata tctatggtat tggtaacact actgctaaaa
    12301 agatcttagc tgatgctggt gtatctgaag atgttcgcgt tcgtgaatta acgaatgaac
    12361 aaacagatgc tatccgtgca gaagtagata aattaaaagt tgaaggggat cttcgtcgtg
    12421 aagtgaactt gaacatcaaa cgtttgatgg aaatcggttc ttaccgtgga atccgtcatc
    12481 gccgtggatt gcctgttcgt ggacaaaaca cgaaaaacaa tgcacgtact cgtaaaggcc
    12541 cagctcgcgc tatcgctggc aagaaaaaat aattcttaag tgaaggaggt taaaacttca
    12601 tggcagcaaa aaaagtgaat cgtaaacgcc gtgtgaagaa gaatatagaa gcaggtattg
    12661 cacatatcca ttctacattc aataacacta tcatcatgat cactgatact cacggaaatg
    12721 cattagcgtg gtcatcagct ggttcattag gtttcaaagg aagcaaaaaa tcaactcctt
    12781 ttgccgctca aatggcagca gaaactgcta caaaagcagc aatggaacac ggattaaaga
    12841 ctgttgaagt aacagttaaa ggacctggtt ctggacgtga agcagcaatt cgttcattac
    12901 aagctacagg tttagaagtg actgcaattc gtgacgtgac tccagttcct cataatggtg
    12961 cccgccctcc aaaacgccgt cgtgtttaat gagtgccgct cattttgagt tttatcagta
    13021 acgtcattga acaagacact tttcgttttg aaaggggtaa agataagaat gattgagttc
    13081 gaaaaaccaa gaatcgcaaa aattgatgaa gaaaaagatt atggcaagtt catcgttgaa
    13141 cctcttgaaa gagggtatgg gactacttta gggaattccc tacgtcgtat tttattatct
    13201 tctttgccag gtgctgccat cactaatatt caaatcgatg gtgtactgca tgaattctct
    13261 accatcaaag gtgttagaga agacgtcact caaatcatct tgaacattaa aggcttagcg
    13321 ctgaaaatgt atggccaaga agaaaaaacc cttgaaatcg atattaccgg acctgctaca
    13381 gtaactgctg gcgatattat cgttgatagt gatgtagaaa ttcttaacaa agatatgtac
    13441 atctgtagtg tctctgaagg agctacgttc catgctcgct taacagtgaa acctggacgt
    13501 ggttatgttc aagcagatga aaataaaaaa gaagatatgc caattggcgt tcttccagtc
    13561 gattcaatct acacacctgt tcgtcgtgtg aactatcaag ttgagaacac acgtgttgga
    13621 caccgtgaag attttgataa attgacgatg gagatttgga cagatggttc aattgaaccg
    13681 ttggaagcaa tgagtttgtc tgcgaaaatc atgactgaac atttggatat ttttgtgaac
    13741 ttaactgatg aagcaaaaaa tgctgaaatc atggtcgaaa aagaagaaac acaaaaagaa
    13801 aaaatgttgg aaatgacgat cgaagagtta gacttgtctg ttcgctctta caattgtttg
    13861 aaacgtgcag gaatcaatac tgtacaagaa cttacaaata aatctgagcc tgaaatgatc
    13921 aaagtccgta acttaggacg taaatcatta gaagaagtta aagcaaaatt gcacgactta
    13981 ggtttaggtt tacgtaaaga agattaaaac cttttacgaa ggagggaaac caacgtgagt
    14041 tatcgtaaac taggacgcac atctagccaa cgtaaagcga tgttgcgtga tttaacaact
    14101 gatttattaa tcaacgaacg tattgtgact actgaagctc gtgcgaaaga agttcgctca
    14161 actgcagaaa aaatgatcac tttaggtaaa cgcggagatt tgcatgcacg tcgtcaagct
    14221 gcggctttcg tacgtaatga agttgccagc gtgcgtgaag aaaatgagga catcgtcatt
    14281 gaatcagctt tacaaaaact gttcaacgat attgcacctc gttacgcaga acgtcaaggc
    14341 ggatacacac gcattttgaa gacagaacca agacgcggtg atggtgcacc aatggttgtc
    14401 ttagaacttg tctaaaatca cactaataac atcactttat agatgattct tttagagtgt
    14461 tatgatgttg gaagatattt ttccgagtct agctcagcgc tgctcctcaa gcgaatatcg
    14521 cttggggagt aagcactcat cataaagtgt ttttttatac cttcaattac ctgtcatgac
    14581 agatatgttt gaaggcataa aaaaacattt taagcgagaa ataattgaaa attttgtctt
    14641 tttttgatag tgttagtagg aactttagga tgaagaagga gtaatcatgg agccaattat
    14701 tgaattagaa aagataaatt ataaatacca gccagatgat cttcgccccg cattgaaaga
    14761 tgtctccttt acaattgata aaggtgagtg gatcgctatt attggacaca atggttcagg
    14821 aaaatcgaca cttgccaaaa cgatcaatgg attgcttctg ccagaatcag ggatcgtgaa
    14881 agtgggaaat caaatattgg atgaagaaaa tatttggacg atccgacaga tggttggaat
    14941 gatttttcaa aatccagaca atcagtttgt tggttcgaca gtagaagatg acgttgcttt
    15001 tggtcttgaa aatcaaggga ttcccagaga agaaatgcta gtgcgtgtga aagatgcact
    15061 tgagaaagtt agaatggctg agtttgcttc acgcgagcct gctcgtttat caggagggca
    15121 aaaacaacgt gttgccattg ccggcgtggt tgccttacga cctgatatca ttattttaga
    15181 tgaagcaacc agtatgctag atccagaagg tcgtgaagaa gtgatctcta cgatcaagaa
    15241 gatcaaagaa gaaagtcaat tgaccgttat atctatcact catgatattg atgaagcagc
    15301 taatgccaat cggatactag tgatgagaca aggcgaactt gtccgtgaag gtacaccaaa
    15361 agaaattttt tctgctggtc ctgaactgat cgacttaggt ctagatctac catttcctga
    15421 aaaactgaag agcgcactga aagaacgtgg ggttgatgtg cccagtgaat atatgacaga
    15481 agaaaggatg gtggattggt tatggacatc cgttttgaac aagtagactt cacttatcag
    15541 ccgaatacac catttgaaca aagagcctta tttgacatca atatgacgat caaagaaaac
    15601 agttatactg cattagtagg gcataccgga agcgggaaat caaccttact tcagcatttg
    15661 aatgcgcttg ttaagccaac aagcggtaca gtccatattg gagaacgaga tattcagccg
    15721 gatacggata ataagaattt aaagcccatc cgaaaaaaag ttggcatcgt ctttcagttt
    15781 ccagaagcac agctattcga agaaacggta gcaaaagaca ttgctttcgg tcctaaaaac
    15841 tttggtgtca gcgaagaaga agcactagtc ctagcaaaag aaacattaga acaagttggg
    15901 ctggatgaaa gctatttgga acgttcgcca tttgaacttt caggagggca aatgcgtaga
    15961 gtagcaatcg ctggtgtgct tgccatgagg ccggaagtac ttgtattgga tgaaccaacg
    16021 gcaggacttg atccccaggg cagaaaagaa atgatggaga tgttttggcg tcttcataag
    16081 gaacagcaga tcactattgt attagttacg catttaatgg atgatgtagc caattttgca
    16141 gattatgtct atgtgttgga aaagggacga atcgttaata gcggggagcc gcaagaggtc
    16201 tttcaaaaca ttgaatggct aaaagaaaaa caactaggcg tacctactgc caccgagttt
    16261 gcagaagaat taatggctaa agggatgaac tttgctacct tgcctttgac agctgaagaa
    16321 ttagcagacg ctatcgtcca ttatgctgga ggaaatgccc atgatgaata aattgatatt
    16381 tggtcgttat atgcctggag attccttgat ccatcgattg gatccccgag ctaaattatt
    16441 agccagtttt tattttatcg gaatcatttt tttagcaaat aattgggaaa cgtacctttt
    16501 gttggcattt ttcacattac tttctgtctt cttgtcaaaa gtagatttga aattttttat
    16561 ccgaggcatt cgcccattga tctggctaat cctcttcact gtagctttgc aggtcttgtt
    16621 tacaagtggc ggagaaactt attggagttg gggtgttttc catatcactg aatttggtgt
    16681 gatgaacggc ctctttattt tctgtcgatt cgtgttgatc atttttatgt cgactctact
    16741 cacgcttact acaccgcctt tggaattatc ggatgcgatt gagtacttgc ttcgtccatt
    16801 gaaagccgta cggttcccag tccacgaaat ttcattgatg ctgtcgattg ctcttcgttt
    16861 tgtgcctaca ttgatggacg aaacagaaaa gatcatgaac gctcagcgcg ctcgcggtgt
    16921 tgattttggt gaaggaaacc tagttcagaa aatgaaagca gtcattcctt tgctgattcc
    16981 tttatttgtc agcagcttca accgtgcgga agatcttgcg actgctatgg aagcaagagg
    17041 ctacaaaggt ggggaaggaa gaacgaaata tcgtgtattg cattggcata atagagacac
    17101 gatggttatc attgcttttg tattattaac tgtgctactg atctttttaa gaggataaac
    17161 gttcagtggg ccgctatcta ttcttttctt gctgatctgt ttgcaagaaa ggatgcaagc
    17221 agtgtatgac aagaaatatt agggtctgtg gcagactaag gtcacaggcc tctttctttt
    17281 atctgaaaag aaagaacgaa aaaattttat agaaaaatca ttattccaga taacctttta
    17341 ggaacaaagg agagaaaaac atggtacgtt acaaagcaat cattgcgtac gacggaacaa
    17401 attttaatgg attccaaaaa cagccaaatg ggcgtactgt tcaagaagaa gtagaaaaaa
    17461 cattacaaaa aatggcaaat ggaaaagaaa tcacggtctt tggttcggga aggacagatg
    17521 ccggagtaca tgcgatcggg caagtaatcc attttgatta tccagaggag cgtccgttag
    17581 aacgaatgcg tttcgcgcta gatacccagt caccagagga tattgctgta agacaagtag
    17641 aaattgtttc agaagacttc cacgcaagat atttggtcaa agaaaagacg tatcaatttc
    17701 gagtggatat agggaaacca cgcagtcctt ttcgacgcca ttatgcaagt tattttcctt
    17761 acccacttga tttggaaaaa attcagcggg cgcttcctga tttattaggg actcacgatt
    17821 tcacctcttt ttgtgcatca ggaagctcga tagaggataa aatacgtacg atctacgagg
    17881 ctaagatgga ggtaaatgaa acaaaagacg aattgttgtt tacatttagg ggaaatggct
    17941 tcttgtataa gatgatacgg atcttagtag gaacgctttt gaaaattggc aatggccgat
    18001 tgcctgaaga tagtatccca gatattattg cgaaaaaaga tcgtaatgca gcaggaccta
    18061 cagcacaccc tgaaggactt tatttgtatg aagtgaaata tgaataagag gttatgatag
    18121 aagtggtcag cttcaagaaa taagaaggta tttacgaaaa ttacttctca aaattttgca
    18181 aaatttcggc ttattttcga agaagctact tctggaacac cgtttaagga agaggtcgtg
    18241 aaatcagcgt tttgacctga gtattagaga aacaaacggg aaaatagctc ctcatatttt
    18301 gccgtttgtt gagctaatac cgaaggtcag ctgattgaac accgtttaag aaagaggtcg
    18361 tgagcctgtc atttaactct gagtcacaaa gagcaatttc aaaaaacagc ttctcatctt
    18421 tgatgaatat cgtgacttgt ggacgaggcg ttgataagtg aatcatcttt ttgttaccta
    18481 ttttttctgt aaccaaaaaa cgatggaacg ttgttttgat tgcccttggt gcggacagtc
    18541 tgaacaggtt ccatcgtttc tttattttct acgtcttctt ctgtgtgtgt ttcgtggttg
    18601 ttcttctatt gctggatcaa tcgtgccata aaaggggcga ttgcggtcaa ggtaccagac
    18661 ataaagaata aacaatgcaa tacataggac aaaaaggatt gcacctatcg taaatccttc
    18721 aggcaagtaa ctgaaagtga cagtatgttt acctgctgga acttttatca tcaagaatgc
    18781 gtctttgaaa ttgctgacct tgactggttt cccatcaatt ttagctttcc atcctttgtc
    18841 ataaggaata gttgtcacca acatggaatc ttcagcggta tttacagtcc cagaagcttt
    18901 tctgccagtg gcttccattt cgacaccttt ttctttgatc tgattcattg cggcttgata
    18961 ggctacaaca tctagaccaa cgactttagg ctccatgaaa cttatttctt tcgtcccata
    19021 aaaacttgca gtaaatgtca ctgttgtctc ttgaggataa tagccaagat catagtattg
    19081 accagaaatg ttgatttgcg tttttcgcga tgtaccattg acagtgatcg tcgcactaga
    19141 actttctaat tgcgcaaaat tggttgggaa caaacttaag taagcttgtg tatttgcagg
    19201 cacatggact tcccaagtga gctcttttgg ctggttatct gctgtttctg agtaagtgac
    19261 gccagtcgtt gtctttgtga tcgtcgtatt caactgattc ttcaaagtag gtgtatagaa
    19321 tgtaaaatac tgttcattta gaccagacaa tgtattgatc aagtttgtct gactggtcaa
    19381 attatctgtc actggctgct caacatcatt aacggacaac ggtgcagtaa atgctagtgg
    19441 caatgcattg acattctgat acagtgtata gtcgccgctt tgaccagctt ggcggaagcc
    19501 atatttactg aacgtgcttt cgtttttaga aatgttatat ttgattcctg taaacccatc
    19561 catcagcaaa gtattattgt tataacggat attcaaattt gtccctcttg aacggaaacc
    19621 taatttatcc aggtaagagg aagaattacg atttcttata gaagaaaaca aactgatacc
    19681 actgtaacca tagttgatcg aatcgtttgc agatactgga tccagatttt ccaagcggta
    19741 aaacgagtcg gaatcttttt ttgtttcatt tacaagagct ttcaagtcag gataaggatc
    19801 agtatataaa ctgcgggaag cataattcca atcatcaaga atgccatgga tcatactgtt
    19861 cgtattgacc agtgcttcag cagacatgat caataataac aatatactca gatgattgaa
    19921 tgaaagtttt ttatgctgat aaaatcccac agcaaaagca taaatcccta agaaaaccac
    19981 tgtcaataca aaggaagtca tcgtcacata ggtgtagctt ccttcaggtt tgatgcccca
    20041 tgccaccgca aagagagcag ctacgaccaa aatgattcct aacaacagcc cacgatcgtc
    20101 ttgttctatc ttttcccatc cttttcctgc aagcaggagc actaagaaag agaacagata
    20161 ggcataacgg aataaaaaca tattcggtgc atgcatacca tgccagaaca aattcaatgg
    20221 aacaagataa aaacttgcga taagtatggc gaaaagactg ccgtacaaaa atttattttt
    20281 caacggtact ttccgactgg caaaataaaa cagacagagg actaatggta gcagacctgc
    20341 gtaaacgaac ggaatcgatc cgtattttgt cgtgtcataa acaccaatca tatttttcat
    20401 gattagatcc agataagaag tcgcttctgt tttcaacgta gtgatctgac tcagtgcctc
    20461 gccatttgac cgaagatcca gcactgctgg caatacaatg atcattgaag cgccgcctgc
    20521 cagtaaagaa gtgataccat aaggaacaat cgttttttta tattctgacc agtttgtcaa
    20581 tagacgggcg ataaaatata agaaagaaaa tacgccaatc ataaaaccca tataaaaact
    20641 ggataaaaac aagagtaaat aactgataaa taaaagtttc ggccgtttaa gatccataac
    20701 acgatgaatc cccaaaatca ctaatggaag ataaacaaat gcatccagcc acatgatgat
    20761 ctccgaatgt gcagtgataa atgagatcaa tgcgtaactg acgctaagtg caacatgccc
    20821 ccagcgagga atcttgaacg tacgtgcaag aaaccaaaaa gccaatccgg cacagccgac
    20881 cttaagcaaa gtcagaacat acagtgcatc tggcatcatc tggtttggaa aaaagaacac
    20941 cagtggcgtg aagatcccgc ctagatagta agaaattaaa gataaataat tcaatcctag
    21001 agaagcattc catgtataaa aaatactttg ctttccaaga agaacatttc ggaagctggc
    21061 atgaaaatta gaaaactgtg aaaaggcatc acttgccaaa atacttctgc tgcttccagg
    21121 atagattccg atacttagat aaacaagtgc taaaatcaaa aacggaatca ggaaactagc
    21181 tgctgcgtag cgtccgtttt ctctaaagaa tgactttaaa ttttttttca tatttatttt
    21241 ccaccaaatt tctatgaagt tgtattcagt ttatcatatc cttgtttttc tctgcttaaa
    21301 aagagtctag ttttcacaaa aaaataaaat ttagaataaa taacttcata atttgttcgt
    21361 ataacaaaaa taaacgcaaa aaaagggtag gaatcaaaag tcccaccctt aaaaattttt
    21421 attaaataaa aaaccgttca ctatctgaac ggtccaagta tcattcaatt aaacgcgttc
    21481 aacttttcct gatttcaaag cacgagttga cacccaaact tttttaggtt ttccgtcgac
    21541 cataacgcga actttttgta agttaggttt aacagtacgt tttgttgagt tcatagcgtg
    21601 tgaacggttg tttccacttt ttgtcttgcg acctgtaaag taacaaactt ttgccatggt
    21661 aatttcctcc tttgccttga tttggagcaa tagaataatt cagctcatac cagactaaca
    21721 tatcatatag aatgggaatt tgcaagtaca ttttcataga tacaattgac aattgagaag
    21781 aataattgta aattaaacaa ggttatacct gaaattttgc aaggtttttg agtactttgg
    21841 gtaactgcct tttatttcaa gttgcgctat gataaaatat gatagaagaa aaatgggagt
    21901 tttttacccg ttaaggaggc tcattcatgg ctgtaaaaat tcaaacgtca gctggaacca
    21961 ttgaaattac caatgatgta attgcaacag ttgttggtgg cgccgcgaca gatgtgttcg
    22021 gtgttgtagg aatggccagc aaaaatcaaa ttaaagataa tattactgag attttgcgta
    22081 aagaaaatta ctcaagagga gtagttgtcc gccaagaaga taatggtatt gctgtagatg
    22141 tttatacgat tatcagctat ggtacgaaaa tctctgaagt ttcccgcaac gtccaagaaa
    22201 aagtgaaata caatctagag gcattattag gcgtaactgc caattcagtt aatgtctttg
    22261 tacaaggtgt tcgtgtactg ccagactagg caggagactg gctggtaact cagcagtcga
    22321 tctgaaggag gattatctag gtgagtgtaa cagaaataag tgcaagccag ttccaggaaa
    22381 tggtccaggc aggtgcgaat cgtctgcaag taaatgcaga atacgtcaat tcattaaatg
    22441 tattccctgt gccagatggc gatacgggaa caaatatgaa tctatctatg actagtggag
    22501 ctaaggcagt agtagattca acctcagaaa aagtaggaga attagcagca atgctttcaa
    22561 aaggattgct gatgggtgcg cgcggaaatt ccggcgttat tttgtctcaa ttgtttcgtg
    22621 gattttctaa gcaaattcca gatgttgtct cattaaatgc ttctgatctt gctgcagcct
    22681 tcactcatgg agttgaaact gcgtataaag cagtaatgaa accagtagaa ggaacgattt
    22741 tgacagtagc tagagaagca gcgaaagctg gagaaaagaa agcaaaaagt actgatgatg
    22801 tcgttgaagt aatgacagct gttgtaaaag gagcaaagcg tgctttagct aaaactccag
    22861 acttgcttcc agtcctaaaa gaagtcggtg tcgtagacag tggagggcaa ggactgctgt
    22921 ttgtttatga gggcttttta agtgcattga atggagaatt ccaagcggat gaaacatatg
    22981 aaccttctcc agcagaaatg gatgatatgg tcaatgcaga acatcatcgc agtgtccaag
    23041 gtcaaatggc gacagaagat atccattttg gttactgtac agaaatcatg gtaaaaatcg
    23101 gagaaggacc tacagtcgat agtacattcg attacgaaga attccgtaac tatttagatg
    23161 gtataggaga ttctttactt gtggtcaatg atgacgagat catcaaagtc cacgtgcata
    23221 cagaaaaccc aggagaagtc ttgaattatg gacaaaaatt cggttcatta gtcaaaatca
    23281 aagtcgacaa catgcgcttg cagcatgaga cgattttgga acacgatgaa gaagtgaacg
    23341 agtttgcgaa aaaagaaata ccacgtatcc cgtatggtat cgtagcgatc gctgctggta
    23401 aaggcgtcca agagctgttt gaaagtttag gcgctaatta tgttatcagt ggtggacaaa
    23461 caatgaatcc aagtacggaa gacattgtta aagcgattca agaagtaaac gcagataaag
    23521 tgattgtctt gccaaacaat aagaacatct tcatggcagc tgatcaagca gcagaagtag
    23581 cagatatccc agtagcagtt gttccttcaa gaacgatttc ccaaggattg acagctatgc
    23641 tttcattcaa tgatcaagct tctttagaag aaaacaaaga aacgatgaca gaaatgttgt
    23701 ctagcgttgt gagcggtcaa gtcactcacg cgatcagaga tacctcaatt gacggtgtag
    23761 agatcaaaga aggagacttt ttgggcatga tcgatggaaa aatcctgatc tctaacccag
    23821 atatcacagc aacagcgtta agtacactag aacaaatgat caatgaggac acagagatcg
    23881 taacgatctt ggcaggtgat gaaggaacag ttgaacaagc aaatgaattt gctgagaaac
    23941 taacagaaaa acatcctgat ttggaaatcg agatccacca aggagatcag cctgtctatc
    24001 cttatctatt ttctgctgaa taatttctgt gtcagaatat ctttctaaca cagtattcat
    24061 tcataaaagg ccttcggtta gtgatcaggt atgatcgctg accaagtcct ttttttgtta
    24121 aaggagggag gaaaaattta tgcgttcttt agatgatcca atcactatgc tggcaggagt
    24181 cggagaaaaa agagcagcta gtcttgccag cttgggcatc caaacgattg aagacttact
    24241 gacttattat ccttttcgct acgaagatat tcaggaaaga aatctaaacg agatccagga
    24301 tcaagaaaag gttactttga aaggaatcgt agtctcgcct cctgtgatga atcgatttgg
    24361 ttataaaaaa agccgattgc aatttcgtat gatgcaagaa catgatgtgt tcaacgtttc
    24421 tttttttaat caaccttatc taaaagaaaa agtcatttta tcggaggaaa tcgccgtata
    24481 cggtaaatgg gatgcaaagc gtaaagcctt gaacgggatg aagattttag gttctcaaac
    24541 aatggatgac ttttcgccga tatatcacgt caacaaatca attcgtcaaa cgacattagt
    24601 tgatctaatc aaaaaagggt ttcaagaata cggcacattg attgaagaaa atctgccaaa
    24661 caaccttgtg gagaaatatc gactgcttga ccgagcttct gctgtaagaa gtatgcattt
    24721 tccaaaagac cacgaagaaa accatcaagc caaacgacgt gtcgtttttg aagagttctt
    24781 tttatttcaa atgcgtcttc aaggattgaa aaaagcagaa aaagcagaaa cgaatggttt
    24841 ggagatcctt tatgatgtcc aaaaattgaa acaatttact caaaagctac cttttgaact
    24901 gacaaatgca caaaaacgtg taacgaatga aatctgtcgg gatcttcgca gtccgcagca
    24961 tatgcagcga cttttgcagg gagatgtagg tagcggaaaa acagtggttg ccgcgattgc
    25021 gttatacgct accgttacag caggtttcca aggtgcgttg atggtgccta cagaaatctt
    25081 ggcacaacaa catatggaaa gcttgcaaca gctgtttgat cccaatgaag taaccatcgc
    25141 attgattacg gggtcaacga aagcaaaaga acgacgtgag ctccttgaaa aactagagca
    25201 aggggaaatt aacgtcgtga tcggcacaca tgcattgatc caagatggag tcgaatttca
    25261 gaatttaggt ctagttatta cggatgagca gcaccgtttt ggcgtgaacc agcggaaagt
    25321 acttcgtgaa aaaggctggc gaccagatgt cttatttatg acagcgactc cgattcctag
    25381 aacattagct attacagcat atggtgagat ggatgtatct atcattgatg aacttccagc
    25441 tggacgtatc ccgatcgaaa cacgctgggt aagaacacct caattggaca gtgtactgga
    25501 ttggacgaaa aaagaactgg caagaggaca tcaaatgtat gtcatctgtc cgctgattga
    25561 agaatcagaa gcattagatg taaaaaatgc agtggaaatc tatgaaaaac ttcgtgaact
    25621 atttgcacca aaatatgaag ttggcttgtt acatggtaaa atgaagaatc aggaaaaaga
    25681 agtaatcatg gaagccttca aagacaacca gatgcagata ttagtttcga ctactgtaat
    25741 tgaagtaggg gtaaacgtgc cgaacgcgac cgtcatgctg atcatggatg cggatcgatt
    25801 tggattggca cagctgcacc aacttcgtgg acgtgttgga cgcggaagtg atgcttccta
    25861 ctgtatctta gttgctaatc ctaaaaatga actaggtgtg gaacggatga aaatcatgac
    25921 agagaccacc aatggttttg tactaagcga aaaagatctg gaattacgtg gtcctggtga
    25981 agtatttggc ttccgtcaat ctggtctgcc tcaatttgcg attgctgact tggtgacgga
    26041 tggaaatgtt ttggaggtag ccagagaaga ggctgcagcc ctttggcaaa taaaggattg
    26101 gcagatgctt cctgagtatc agcctttagc gcaaagcctc caaatagaaa atcaggataa
    26161 tcgttatttc gattagcaga ctgtgctata ctttatactg atgacggaaa aaggagtgga
    26221 aacaatgaaa attgccgtag atgcaatggg cggagatcac gcacctcaag caattgtaga
    26281 aggcgtggct ttagcgcagc aagattttcc agaagtagaa ttcttacttt acggaaaaga
    26341 agcagaaatc aagaaatact taacaaatga aaaaaacatc acgattatcc atacagacga
    26401 aaaaatcaat agtgatgatg agccagtaaa agcaattcga cgaaaaaaga ctgcatcaat
    26461 ggtccttgct gcacaagcag tgaaaaacgg tgaagcagat gctgtatttt cagcagggaa
    26521 tacaggcgcg ctactagcag cagggttgtt catcgtagga cgtatcaaaa atatcgaacg
    26581 ccctggcttg atgtctacct tgccagtagt agggaaagaa ggtgccggtt tcgatatgct
    26641 ggatcttggc gctaacgcag aaaacaaacc agaacatttg ttgcaatacg gtattttagg
    26701 ttctttttat gcacgtaaag tccgaggtat cggacgtcct cgtgtcgcac tcttaaacaa
    26761 cggaacagaa gcaacaaaag gtagtgaagt gacgaaaaaa gcctatgaac tccttcagaa
    26821 tgaaacaagc ttgaatttta ttggaaacgt agaagctcgt gagctactca atggtgtggc
    26881 tgatgtagtg gtcacagatg gatttacagg caacgctgtt ttgaaatcta ttgaaggaac
    26941 agcaatgaat atgatgaatc tattaaaatc tgctattcta aatgaaggga tcaaaggaaa
    27001 aatgggcgct atgcttttaa aagacggctt acgttctttg aaagcagaaa tggattattc
    27061 caaacatggc ggtgccgttt tgtttggctt gaaagcacca gtcattaaaa ctcatggagc
    27121 aacaggcccc gatgctgttc gctatacgat ccgccaaatc cacacaatgc ttgagacaga
    27181 tgtagttgga caattagtcg aacaatttga aaaaagcgaa gaatagtatt tggatatctg
    27241 aagcgatccg ttccattgaa aaaaaggtgg acattcctga aaaatgccag taaaattagc
    27301 catggtgtag gtaattgaca agtgtatgat tcttggaggt gaaaaagttg actcgcgaag
    27361 aagtatttaa caaagtagcg aaaattattt caaatcattt tgagatagat accgataaag
    27421 tgacggatga attgaacatc aaagatgatt taaaagctga ttcaattagt attatggaat
    27481 tcgttttaga gcttgaagat gaattcggta cggaaatttc agatgaagac gctgaacaaa
    27541 ttgaaacagt cggtggcgca gtagattata tcagcagcca tcttaaataa tttcaaataa
    27601 aagcaaagaa ggataaaaag ctgcatgcag ctttttatcc ttcttttttt aatctttttg
    27661 acacgtaaaa gtcatttttc tgataattct ggcgataaac agaaattatg ttgcaaagta
    27721 aagcggtttt ctatataatt attaataatt cattacacaa agataagaat aacctttgtt
    27781 ataaaacgat ttattctgtg taatgtcctt ttttattaag aaaaacttcc atttaggaag
    27841 cagagagggg tattcgattg tccgataacc aattattaga agttcagaac ctacatacag
    27901 gattccgact caaagatgac tattacgatg cagtagatga cgtttcattt actttagaca
    27961 aaaacgagat tttagcaatc gttggggaat ctgggtgcgg gaaaagtacc ttggctacta
    28021 cgattatggg attacttgat cctaataaca caaaaattac aggtgagatt ttatataacg
    28081 atctgaattt aatcgacctg aacgaaacgc tctataataa aatccgcgga aatgatatcg
    28141 gaatgatttt ccaagatccg ttgtctgcat taaatcctct catgagaatc gaagaccaga
    28201 tcaaagaagg actttcctat cacacaaaga tgaatgcaga acagcgtcaa gctcgtgcac
    28261 tagaattgct agaacaagta gggattccta atcctgcgag agttggacgc caatatcccc
    28321 atgaactatc aggcggtatg agacaacgtg tcatcatcgc aatcgcaatc gcctgcaaac
    28381 ctccaatcgt cattgcagat gaaccgacga cagccctaga tgtaaccatc caagcacaga
    28441 ttcttgattt actgaaagac cttcaggaag aaacaaaaac agggatcatc ttgatcactc
    28501 atgacttagg agtcgtagca gaaatggctg atcgagtggc agtgatgtat ggcggacagt
    28561 tcgttgaagt agcaggtgta aaagaactgt ttgatcatcc taagcatcct tatacacgct
    28621 ctttactgaa ctctatacca caagaaggaa atcatgatgc agaactccat gtgatcgaag
    28681 gtgtcgttcc ttctctgaaa aacatgcctc gtaaaggttg tcggtttgca ccacgtattc
    28741 catggatacc agcaagcgat catgaagaag agcctatcct tcatgaagtc gcaccgaacc
    28801 acttggtacg ttgctcctgc tataagcatt tccactttag agacgaaaaa ggagaggtgt
    28861 agatgacaga attaatcaca atcaaagacc tgaaagttca ttaccctatt cgcagtggat
    28921 tcttcaatcg agtaacggat catgtatatg ctgtagatgg tgtggatttt attatcgaaa
    28981 aaggaaagac atatggttta gtgggagagt ctggctctgg aaaatctact acgggaaaag
    29041 ccgttgtggg attagaaaag gtaacagccg gacaaatcat gtatgaagga aaagatgtaa
    29101 cgaagcgaag caaccgcaaa aaaatgggtt ataacaagga tgtgcagatg atcttccaag
    29161 attcaatgtc cagtttgaat cctaaaaagc gagtgttgga tatcattgct gaacccatcc
    29221 gaaattttga acggttaagc gatcaagaag aaaagaaaaa ggtaaaagga ctgctagata
    29281 tcgttgggat gccggaagat gcgctatata aatatcctca tgaattttca ggcggacaac
    29341 gtcaacgtct aggagtagcc cgtgctgttg ctaccaatcc aaaactgatc gtagccgatg
    29401 aacctgtatc tgctctggat ctatctgttc aagcgcaagt attgaatttc atgaaacgaa
    29461 tccagcaaga atacggcctc agctatttat tcatttcaca tgatttaggt gtagtaaaac
    29521 acatgtgcga caatatcgca attatgtaca aaggtcgatt tgtagaaatc ggtacaagag
    29581 aagacattta taatgacccg cgacatatct atacgaaacg tctgctttca gctattccgc
    29641 aaatcgatgt agaaaatagg gaaagccaca aagaaaatcg acgaagagta gaacaagagt
    29701 atatccaaaa ccaaaaagaa tactatgatg cgactggtcg agtctacgat ttgcgtacga
    29761 tcacaactac acacaaagtg gcgttgaaag atggaggtgc aagctaatgt ggaaaacgat
    29821 tctgcgacgt gttttattga tgatcccgca agttattatt ttaagtgttc tgatcttctt
    29881 attagcccaa gcgatgccgg gggatccatt taccggtttg atcaatccaa atcaggatcc
    29941 ggcagtgatc gaacagatgc gacaagcagc tggcttgaat gacccatggt atgtccagta
    30001 cttccgttgg atcggaaatg ctttgcaagg cgattttggt caaagtttct tatacaaacg
    30061 ctctgttgct gacttgatcg gcgaacggat catcaacact ttatatctat cgatcttgac
    30121 agttgtcctt acttatttga ttgctgtgcc tctggggatg cttgctggcc ggtatcaaaa
    30181 ttcaatcttg gataagattg tcgtaatcta caacttcttt agttttgctg ttcctttatt
    30241 tatcttcggc ttgatcatgc tatttgtttt tggttatcgt ttaggctggt tcccaacaag
    30301 tggatcacaa acactaggtt tgcaaggtgg atttatcact caatggatag accgtttgaa
    30361 atatattctg ttaccatcaa ttacccaagc atttttggcg actgccgtca caatccaata
    30421 tctgcgaagt gaagtaatcg attcgaaatc gctcgatttt gtcagaacag cccgttccaa
    30481 aggggtaccg acgaataaag tattcagtcg acatattttc cgaaatgcag cgttgccgat
    30541 ggcttctcaa atggggtatg aaatcacttc gttgattgct ggttctgtag ttatcgaaaa
    30601 gatttttggt tatccgggag tcggaaaact atttattgat tccatcggcc aacgggacta
    30661 taccgtgatc acatccttag tattgatttt aggaatcgcg acgctagtgg ggacattact
    30721 ttcagatatc atcatgagta tcgttgaccc gcgtattcgg attcaataaa accaatcaga
    30781 aaggagaatg gatcgatgag tgaaaaaaac aatacagcag ttcaagaaag tattcctcct
    30841 atggggatac gaatgattgc tcgagaattt aaaaaagata aaattgctat tttttcatta
    30901 ggtttgctag tggttttatt attagtgatc tttatcggtg cgatgctgac cgatcaagac
    30961 aaagtgatgt atgttagtat cttcgacaaa tacgctgcac caggaacagt ttcgacacaa
    31021 ggacaaaagt tcattctggg agcagatgaa ggcggacgtg atgtattagg acaattgatc
    31081 ataggtgcta gaaactctgt tacgatcgga tttgcgatca cgatccttac ttcgatcatc
    31141 ggggttggat tagggatcat ctctggctac tacggaggga tcattgacaa catcttgatg
    31201 cggatcgttg attttatcat gattctaccg atcatgctga tcattatcgt cttcgtatcg
    31261 attatttcca gatacaatgt ctggtccttt atattcatca tgagtgcatt ttattgggta
    31321 gctaaagccc gattattccg aagcaagaca ttatctgaag caagaagaga ttatgtcagt
    31381 gcctcaaaaa caatgggaac caatgatttt aaaatcatgt tccgcgaaat catgccgaat
    31441 ctaagttcat taatcattac taatttgacg atgaactttg cggcaaacat cggtatcgag
    31501 acaactttga ctttcttagg tttcggcttg ccggcaaatg tacctagttt aggtacattg
    31561 atcggttatg caagtaacgg agaagtctta gtgaatcggc aatggatctg gttacccgca
    31621 tcaatcctta ttttagtttt gatgttgagt atcaattatg ttggacaagc attcaagcgt
    31681 tctgcagatg cgcgccaacg gttaggctag tatagaagcg aagggggaaa taggaatgaa
    31741 gaaaacgatt tttggatttg cagcgctgat gtctgctgtc gttcttgcag catgcggggg
    31801 cggaggtaca gatacctctg gaaacaactc tggaggcaac ggcaataaca aagaggaatt
    31861 aacttttcca attgcaacaa aaaataatga tgatgcaatc gaagacggcg aattagaagc
    31921 tgcggtcgca acggacagtc agtttaaagg attgttccag tgggagtttt accaagattc
    31981 atatgatgca gcttttatgg ctccttctca tgaaccgcta tttgcaaacg atgacgattt
    32041 cagaatcaca gacgacggag ctgcaacgct tgatctagat gaagatacga aaaaagcgac
    32101 aatcaaagta aaagacaacg tcaaatggtc agatggtgaa gatgtaacgg cggacgatgt
    32161 gattttccct tacgaaatca ttgggaataa agattacact ggtatccgtt atgacgacac
    32221 tttccgtaac atcgtaggta tggaagaata tcatgatgga agtgccgaca caatctccgg
    32281 aatcaaaaaa atagacgaca aaacagttga aatcgaatat aaagaagtaa acccaagcat
    32341 gcttcaatcg ggtggtggta tctggtcata tgcagcacca aaacatacgt tagaaggtgt
    32401 agcaatcaaa gatatggaat caagcgatca agtacgtaaa aatccagtga cttttggccc
    32461 ttattacatg agtaatatcg ttgcaggaga atcagtagaa tacttgccaa acgagcacta
    32521 ctggaatggt acgcctaaat tgaaaaagat cacgatgaaa tctgtaccga tggcaagtgc
    32581 aactgaagca ttgaactcta aattatatga tatgattttc caaatgccaa cagatactta
    32641 cgatacctat aaagaaattg ctggctatac aaacttaggc cgtgaacaaa cttcttatac
    32701 ttatctagga ttcaagttag gtaaatggaa tgcagataca aagagtgtgg aatacaatcc
    32761 agattcaaaa atggctgata aatcattacg tcaagcaatg ggctatgcat tagataataa
    32821 tgcagtaggt gaacgtttct atgcaggttt gagaagcaat gcgacttcat tgattcctcc
    32881 agtattccag tcataccatg atgatgagat gaaaggattc acacaagatc tagacaaagc
    32941 gaaaaaacta ttagatgatg ctggctacaa agatgtggat gacgatggtt taagagaaga
    33001 caaagatgga aataaactaa caatcaactt tgcttcgatg tccggtgggg aaacagcgca
    33061 accattggca gattactata tccaacaatg gaaagaaatt ggtttggatg tccaatacac
    33121 aacaggtcgt ctgatcgaat tcaattcttt ctatgataaa ttagaaaacg atgatcctga
    33181 aattgatgtt taccaagctg cttggaatac aggaactgat ccaaatccaa gtggactatg
    33241 gggaccaaat gctgcgttca actacactcg ttatgaatca gaagaaaata caaaattgat
    33301 caacgatatc agttcaagca aagcatttga tgaagagtac caaaaagaag catatcaaaa
    33361 atggcaacaa tatgcatttg aagaagcatt tgcgattcca acgttgttcc gtaatgaagt
    33421 attgccagtc aacgaccgtg tcaaagactg ggattggtct tatgatgtac caaacccatg
    33481 ggcaaatgtt tctgttacag cagattcacg ttcataatca ctaaaaatga ccgaaaaagg
    33541 gcgatgtcct ttttcggttt tttgatattt ttctgtttat ttctctaata ttcaggtcaa
    33601 ggcgctgatt tcatgacttc tccaataaac ggtgttcaaa gtccagtttc tcggtattaa
    33661 gtcaaattta tgcaaaaata tggaaagcca ttttcacaaa attttttctt catactcgaa
    33721 actaaacgaa tttttcacaa cttctcgtca atcactagga ttattaaagc tttacttacc
    33781 ttttgaccga accatttcaa atttgacaaa aaaccagtat aataaggaag tatcgaaaaa
    33841 atatccataa aaggaatgtg gaaaatggac aaccagctga caaaagaact aaaagaaaac
    33901 tataacatcg tttttcacga tctaaatttg cttgaacaag cttttaccca ttcatcctat
    33961 gtgaatgagc atcgcaatct gcaattatcg gataatgagc gacttgaatt tttaggagat
    34021 gccgttttag aactgatggt ttctcagtat ttattccgtt tatatcctca tttgccagaa
    34081 ggaaaattga caaaaacacg agctgcgatc gttcgcgaag acagcttgtc gaaatttgcc
    34141 aaagaatgtc actttgatca atatgttttg ttgggcaagg gagaagagaa ttcaggagga
    34201 cgtacgcgac cagcattgct ttgcgaccta ttcgaagctt ttttaggcgc gttatatctt
    34261 gaccagggat tcgacacgac ccatgcattc atcgaaaaag tgatttttcc taaagtcaaa
    34321 gcaggtgctt tttcacatga gatggatcat aaaacaaaac tacaagaagt cttgcaaaaa
    34381 tcaggtgatg tatcaatcga ataccgattg atcaatgaag aaggtccagc tcatgaacga
    34441 gtattttgga tcgaagttta tgtagatgat caattgattg gcactggaca agggaaatcg
    34501 aaaaaattag cagaacaagc tgcggcggaa aatgcattgg cagcactgta aaagtaagtg
    34561 agggaaagct ttgtatttga aacgaattga aatagccggt tttaaatcat ttgcagacaa
    34621 gacagtcatt gattttgaaa atagcgtcac agcagtggtt ggaccaaatg gcagcggaaa
    34681 aagcaatatt acagaggcta tccgctgggt attaggagaa caatctgcta aaagtctgcg
    34741 aggcggaaaa atgccggata tcatctttgc cggttccgat acccgtaagc agctgaatat
    34801 tgcagaagtc acagtgattt tagacaatag tgatcattat ctgccattgg agtacaatga
    34861 gatcagtgta acccgccgtt atcgacggac tggggaaagc gagtttttca tcaataaaca
    34921 aagctgcaga ttaaaagata tccaagaatt gttcttagat tctggattag gaaaagaatc
    34981 gttctcaatc atttctcaag gaaaagtaga agcgattttc agtagtaaac cggaagaccg
    35041 tcgtgggatc tttgaagaag cagctggtgt cttgaaatac aagcagcgga aaaagaaagc
    35101 agaacagaag ctttttgaaa cagaagacaa cctcagccgc gtccaagaca tcatccacga
    35161 attggaagaa cagttaactc ctttggccgc ccagagtgag gcagcaaagg agtttttacg
    35221 gctaaaagaa acactgactc aaaccgatgt ctctttgatg gttgctgaaa tcaagacagc
    35281 aaaaaaagat tgggacaaca aacaagcaca gcttgcgaaa ttcaatctag aattaggcaa
    35341 actatctgag tcgatccaag aacaagaatc cattttggcg aagcagcgta aagaaaatgc
    35401 gcaagccgat cgtctgatcg aaaaaaatca gcaagtatta ttagatcttt cggaaaaact
    35461 gaagcagaca gaaggacaaa aagatgtttt gcaggagcgg acaaagcata cacaaaaaag
    35521 ctcgcaagaa tatcaaactt cattagcaga agcacaaaaa aaggttaaac attttgaaaa
    35581 gcttcaagaa agcttgatga aagcagcagc agaaaaagaa acagagatcc aaaaagctga
    35641 agcaaatctc ataaaaacac agcaagaatt agaaaaatac caaaaatcaa cgaaagaatt
    35701 attggcagaa ttaagagatc aatatgttga tttgatgcaa gaacaagcag ctgtaggaaa
    35761 cgaactgaag tatctagaac gtcaatatat acaagaaaca gcaaaaagca agcagacgtt
    35821 agccaagcaa tcggaagtag aagcatcagt agaccgattg atcttacaaa aagaagaatt
    35881 gacacaaaag caggcgcagc taaaatcatc tttaactgaa acaaaagaga agttagaaat
    35941 gatccaacaa aacgggaaaa agttccaaga agcattagca aaagaacagc ctaaaatgta
    36001 tcaattaatg aatcaagtcc agcagctacg tgctcgtaag aaaagccttc aagaaatcca
    36061 agaaaactat tttggttttt accaaggggt tcgattggtc ttgcagcata aacagcagct
    36121 ttcgggtatt gtcggagcag tggctgaact gatcgatgtt cctgcagatt tcacgttagc
    36181 tatcgaaaca gctttaggtg gggcagccca gcatgtcatc gttgaaaatg aaaaagatgc
    36241 tcggcaagcc atcacgtatt tgaaacagca aagaggagga agagcaacat tccttccact
    36301 gacgacaatc aaaccaagac aattaccggc tcatatattg acacaagcag cagctgtaga
    36361 agggtttata gggattgcca gtgaacaagt cagttatccc gatcaaatcc aaactgtggt
    36421 tcaaaacctg ctaggaacga tccttttagc caaagactta actagtgcca atgcaatcgc
    36481 gcaaacgatc cgctatcaat atcgagtggt ttccttagaa ggtgatgtga tgaatgccgg
    36541 aggatccatg acaggtggag cgaataaacg aggaaaccaa ggcagtttgt ttgtacaaaa
    36601 tcaagaattg aaacagttga ctagtgaatt tgaagaagca gataaacaac tccaagcaca
    36661 agaaaaaaaa gttcaggagc tgcaacaaga aacagctcgt ttagccgaag aacaagaagt
    36721 tttgcgtaca cgaggcgaac aattacgttt tgaagaacaa gaagcgacaa atcagctaca
    36781 aaacatcata aatgaacttg aacgttttga aaaagaaaag caaatctcaa cttttgagac
    36841 acgtgaactg cagcagttta tcgaagatta cgaaaagcaa acgaacgaat tgaaagacaa
    36901 acaaacagat cttgaatcgc aacgacaaaa aatcgacgaa gaaatcaaat cgttaagtca
    36961 agaaagcgac cagatggaag ccagaagagc acaagtacaa agtcaaaaag cacaagaaca
    37021 agcagatctt gctgtcttga aagagcagtt taatcatctg cagatccagc tccgcggtgc
    37081 ccgagtccaa aaagcagagg caaccgaacg tcaagaagcg atagaaaagc agttggcgac
    37141 attgacagca gacttttctg atcatgaagt cacagaagaa agtttggaaa aacaaattaa
    37201 cgaattatct gctcagcgag aaacattaaa agccgagttg gcaaaagcca aagagcagcg
    37261 agatagaagg caaaaggaga tcgataagct tgaagcagtc ttggcagagc gtaatcgtga
    37321 gcaaaaagca cgactgtcgg aacaatccaa attagaagtc caaaaagacc gagctgaaat
    37381 gattttagat aatcatttga cctatctgca gtcagaatat cagctgacat ttgagaaagc
    37441 ttcccaagac tatcaagaaa caaccgatat cgaagacagt agaacaaagg tttcatcctt
    37501 aaaagaacag attgaaaaac tgggaccagt aaacttaaat tcaatcgaac aatacgaaca
    37561 agtcagtgaa agacatacat tcttagcaac acagcgagat gatctgttag cagcgaaaaa
    37621 ccaattgttt gaaacgatgg atgagatgga tgatgaagtg cggacaagat tcaaagaagt
    37681 atttgaagct atccgtcaag aattcaaaat tgtctttcca aatatgtttg gcggcggtaa
    37741 agctgaatta gtactgacgg aaccaactga tttgctgaaa acaggtattg agattgaagt
    37801 acaacctcct ggcaaaaaac tgcaaagtct aagtttgctt tctggaggag aacgagcact
    37861 tacagccatc gcgttgctct tttccattat ccgtgtctgt cctgttccgt tttgtatctt
    37921 agatgaggta gaagcagcgt tagatgaagc caacgtgaaa cgttttggtc gttacttgag
    37981 cgatttccaa gatgacacac aatttatcgt agtcacacac cgcaaaggaa cgatggtcgc
    38041 agcagatgta ctgtacggag tgacgatgca ggaatccggt gtatcaaaaa tcgtttctgt
    38101 acggatggaa gatatcaatg aagaggcgaa aatcaacgaa acgaaagtgt aggaacgaaa
    38161 atgatcaaat tagtagcaat cgatttggac ggtacattat taaatgaaca aaagctgatt
    38221 tcagatgaga ataaacaagc attagcacaa gcaaaacagc aaggggtcaa gatcgttcta
    38281 tgtacaggac gccccttagc tgcgatggcg cattatctgc aagaattagg actggtagat
    38341 gaaggtgact acagcatcac tttcaacggc ggtttggtac aaaaaaatga tactggtgaa
    38401 atcatggaaa agaaagtgat ggaagtatca gatatccaac gcttatacaa actggctcag
    38461 caattggatc tgccactaga tgttttgtct gacaatgtgg ttttacagct gcctagtgcc
    38521 ccaaggaagc aatccttgta caatgtgttg aataagctgc tgcaattcca accagcggat
    38581 ataagcgata ttacagatga atttgtgctt aataaggcag taatcgctta tgaccaagaa
    38641 gaattagatc ctaaaatcaa agaaatacca gcagaattcc atgaaatgta tgagatcatc
    38701 aaaacaagaa gtatgctttt ggaatttatg ccaaaaggtg ttacaaaagc ttatggtatt
    38761 tctttattgg caaaagatct tggtttgaaa caagaagaaa tcatggcgat cggtgatgag
    38821 gaaaatgatt taccgatgat ccaatatgct ggactaggcg tagcgatgga gaatgctgtg
    38881 cctttcgtca aagaagcagc agatttcgtg acagccagca atgaagaaaa tggcgtagcc
    38941 aaagtgatcc aaaaatttgt attagagtag ggggagtcaa atgggatttt ttgataaaat
    39001 caagcgtgct tttactggcg aagagaaaac agaagaagtt gaagtacagg agaagtacga
    39061 caagggttta gaaaagacgc gtaaaacatt tggtgaacgg atgaatgagt tgtttgccaa
    39121 ttttcgaaca gtcgatgaag acttttttga agaattagaa gaaacactta tcggtgcaga
    39181 tgtaggtttt gaaacagcga tacgaatcac cgaagcatta cgtcaagaag tgaaactcag
    39241 aaatgcgaaa aaatcggcag aagtccaaaa tgcgatcatc gagaaacttg tggatctcta
    39301 tgaagcggaa ggaatcaatg aagtaaatga actaaatatc caagaagacg gactaacagt
    39361 tattttgttt gtcggtgtta atggtgtagg gaaaacaaca agtattggta aacttgccca
    39421 tcagttcaaa aacgaaggta aaaaagtatt gatggcagca gcagatacct tccgcgctgg
    39481 agcaatcgac cagttagttg tctggggcga acgcgctggt gttgaagttg ttcgtggcaa
    39541 tgcaggaggc gatccagcag ctgtcgtatt cgatgctttg gaaagagcaa agacagagca
    39601 ggcagatgtt ttactagttg atactgcagg ccgactgcaa aataaagtga acttgatgaa
    39661 cgaattagaa aaaataaaac gagtaatcca gcgggaatta ccagaagcac cccaagaaac
    39721 acttcttgta ttagatgcaa ccactggtca aaacgcgatg gttcaagcaa aacaattcaa
    39781 agaaacaaca gatgtgaccg gtcttgtttt gacaaaatta gatggtacag caaagggcgg
    39841 tatcgtactt gctatccgta atgaattgca tttaccagtg aaattggtcg gtcttggtga
    39901 aggaatcgat gacttggagc cgtttgatcc aaatgatttt gtcgttggat tgttcaaagg
    39961 attactaaaa gaagaataac ccatgtctaa aaagcaggag ctgtgacaaa agttgcagct
    40021 ccttgtttga atgattgttt ttaacatagc tgtgtttttg atgccttcat ttttatactt
    40081 atttgtaagc ggttctcaaa caatttcgtt ctttttctta gactttttga ttataattag
    40141 attcatatga attggaggtc acttaatgat gaattttaag caattattat tgcatgtcaa
    40201 tgcgcgccct tttatcgacc aagctcgatt tggtatagaa cgggaaggac agcgggttga
    40261 tcttgcagga aatctagcaa aaaccgatca tccagcaatc tttggcgatc gatcctatca
    40321 cccctatatc caaacagatt ttagcgaaac acaaacagag atgatcaccc ctgttaccga
    40381 ttctattccc gaattatttc agtatctcgc tgctgtttat gatgtgactg ctcgttctat
    40441 accgaaagaa gagatgatct ggccattaag tatgccacct gccttaccgg aaaaagacga
    40501 agagatcatt attgcaaaat taaaaaattt cgaagatgtc ttgtatcgac gttatttagc
    40561 aaaagaatac gggaagcgaa aacagatggt aagcggtatt catttcaatt ttgaatttgg
    40621 cgatgagttg ctaagaacat tgttcagcca tcaggaagaa tttcaagatt tttccgaatt
    40681 caaaacagaa ctttatttga aaacagcgag aaactttatg cgctatcgct ggatgatcac
    40741 ttatttattc ggtgcttcac caatgagtga gaagaactac tttttagatg aatcacatcc
    40801 gcaagaacct gttcgcagta ttcgcaacag tgcgctgggc tatacgaatc atccaaatgt
    40861 gaaagtttcc tatgcttcta tgaaacagta tttagcagat atcgagcgaa tgatcgaaga
    40921 agggaaactt tcggaggaga aagaatttta tacaccgctt cgtttccgag gcggaaagaa
    40981 agtcgcagat ttagcaacaa caggtgttcg ttatattgaa ttgcggaata tcgatttgaa
    41041 tccttatgca agattgggta tcaatccaga gcaagttcgg ttcttacaat tattcctgat
    41101 gtacatgtta tggacagaag aaaaagaaga ctgtgaccaa tgggtagcag aaggtacgac
    41161 tcgaaataac aaagtagcac tagaacaacc atcagatcaa acagaatttc atcaagaagg
    41221 tagagaaatt cttgaaggaa tgaagcaaat gctggttgaa ttggattggt tggattctct
    41281 ttatttagta gaggaagcat tgactcaaat ggatcatcct gaacaaacgt tagcagcgaa
    41341 actctatcaa gaagcacagc tatcgagtca gcaagaagtt gctgtggcat tgggacatca
    41401 atattataaa gaaagccatg aacgtcccta tcagttggcc ggttttcgcg aaatggaact
    41461 ttctactcag atatttatgt tcgatgccat ccaaaaaggt gtccaagtca aagtattaga
    41521 tgagtcggat caatttttgc gtctgcaatt ccaagaccat gtagaatatg tgaaaaatgc
    41581 aaacatgaca agtaaggaca gctatatcgt cccacttatc atggaaaaca aaacagtaac
    41641 gaaaaaagtc ttaaaagaag ctgggttccg ggtaccagga ggcgcagaat tttcatccat
    41701 ggaagaagcg gtaaaagctt atccgagatt tgccgagcag gcatttgtga tcaaacctaa
    41761 atcaaccaat tacgggttag gtatcacgat tttcaaggaa ggagctagtc tggaagatta
    41821 tcaagcaggt ttagccattg cttttcgtga agacagttcg gttttagtag aagaatttat
    41881 gccgggaacg gaatatcgtt tctttgtgat cgacggagaa gtccaagcca tcatgttgcg
    41941 agtccctgct aatgttattg gtgacagtat ccgaacagtg aaagaacttg ttgaagaaaa
    42001 aaatagtgac cctttgcgtg gaacgaatca tcgtgcacct ttagaattga tccaattagg
    42061 tgaattagaa caattgatgt tgaaagaaca agggttgacg atcgaatcag ttccccaagc
    42121 caatcaaatt gtttatctaa gggagaactc aaatatcagt acaggtggtg attcgatcga
    42181 tatgactgat gaattttctg aagcttacaa aaaaatcgcc gtttctgcgg tagaagcact
    42241 aggagctaag attagtggta tcgatttgat tataccagat aaagaaatcg atcctacaac
    42301 tgataaaaaa gcatatggga tcatcgaagc aaatttcaat ccagccatgc atatgcatgt
    42361 ttatcctttt gcaggaaaag gcagaagatt gacgatgaat gtattgaaat tgttatatcc
    42421 tgaagtattt taaaagaaaa agcttttgac agattgtcct atttgatgtc aatctgatca
    42481 aaagcttttt ttgcatgtaa aaatttatgt gttttttcgt tttaaaataa acgatcccag
    42541 aagctttttt tcttttttgg tttttctttt tcagctggcg aagagttttc ttctgggtat
    42601 tttttttcga tatcaatcac aggttcattt actgcttctt ttgctgttaa gagcaatccg
    42661 aattcctcag gatttgcagt gacgtaatcg ttgactacag tgaaacggct attgtttttc
    42721 gttgctagct ggatatattg gttttggaca gaaaggggta gagccccatt caagagtatg
    42781 gaagcatctg gatgtttttt gagttctttt aaaaagtttt ctttgttttt tggttggatc
    42841 atttcagcaa cagtcatact aagatagcag cgttccctga atgtccctaa atatttatgc
    42901 tgttcttcag ggttcactaa aggtgtacca taaagtccct tatccaaatg gctttttaca
    42961 tcatcttgtg ccataaaaaa taccctcctt cttctctttg tctttcttac gattatagca
    43021 tattcccaat aatacctaaa acatatgaaa aagcggttgc ttttgttcaa cgattcactt
    43081 aaaataagaa tgaaaatcat tctcaattag aaaggtggat tggatgcgct acggacgact
    43141 agtagcatta ttagttattt taagtagtat ttcattgttc atcggagtat cgaatgtaca
    43201 attgtcagaa ctgctccagt tagatgggca aagcttacaa atcttgctag tgactcgttt
    43261 gccacgaacg atttgtttga tccttgtggg agcgaccagt agtatttgtg ggttgatcat
    43321 gcaacatttg acccaaaata aatttgtttc accaacgact gcgggcacga tggatagtgc
    43381 gcgtttaggt attttagtgg ctatgatttt cctacctggt gcatccttga ttgtccgatc
    43441 cttgacagca ttttgctttg cttttgcagg aacattgctt tttttatccc ttacgcgatt
    43501 gttcctccag aaaaatcaat tgatgcttcc gttgattgga gtcatgttag ggaatatcat
    43561 tggttcagtt gctacttttt ttgcttatca attccagttg gtacaaaata tgacttcatg
    43621 gcttcaaggg aattttgcga ctgtgatacg aggaaattat gagttattgt atgctgttgt
    43681 tccattgttg ctcttggttt ggctatttgc ttaccgattt acgatcattg gtctgggcga
    43741 atcgtttgca gtaaatctgg gaatagatta ccagaagatg cagtttttag gcattggctt
    43801 agtatcattg gctagtgcag tcatgttgat catggtagga agcattcctt ttatcggagt
    43861 gatcattccg aatcttgtct ctagaatata tggagatcaa gtgcacaaaa caattggcgt
    43921 aactgcttta gcaggtagtt tgttcttagt attttgcgat cttgtcgctc gcgtgttgat
    43981 ttttccttat gaaataccag tcagtgtgat cgttggaatc atcggtgggg ctatcttcct
    44041 ttatcttctg ataaggggac gacgatatgc ttaaaaaaaa gccatctatt tttattggta
    44101 tgcttgttct tgttttattt gttacaggaa tgtacttgac gatccataca tatggaaact
    44161 ggcattttgc atgtgcattg aggagtaaga aaatttttgc atttatcctt gtctcgctag
    44221 ctgtcagcag tgccacaatc agctttcaga caattacgca taaccagttt ttgactcctt
    44281 cagtattggg acttgagtcg ttatatgtcc ttgtccaaac ggtccttttc ttctttatcg
    44341 gaggagtgac gatgcttcag cagacaggta cagttttttt cttattgaac gttgggctga
    44401 tggtcgggct gagtctattg ttatttttct ttcttttgaa aaaaatgaga gcgaatcttt
    44461 ttttattact gatgtcaggg atgattttag gtacgctttt tggtagtgtc agtacctttt
    44521 tacaagtcat catggatccg aatgaatatg atttgcttca aggcagatta tttgcaagct
    44581 ttggcaatat ccagagtcag tatcttttgc ctgcttcttt gatcattatc ggctgctggt
    44641 acctgttatt tcgatatcga catgtgctag acgttttcca tctcggaaat gaacaagcag
    44701 taaacctcgg gatagacaca gatcgttttg aatttttgat tttatgttgt gtcagtcttt
    44761 tgacagggac atcaacggct cttgtgggtc cagttacttt tttagggttt attgtcgcaa
    44821 atatcagtta tcgtgtcttt tctacttatc gtcatggtca gctatttatc ggaagctttc
    44881 tggtagctat gctgtttctg acaggaggac agctcgcagt agagcagatt ttcggctgga
    44941 atacaacagt gagtgtcgtc gttgaatttg tcggaggaat ttattttgtc acaaaattga
    45001 ttcgcgaaag gaagagtatc ctatgattga tttacaaaag gtcaataaac tgtaccatgg
    45061 aaaatcagtg gttaaagatg tacagttaac gattcctgaa aagaagttga ctgcttttat
    45121 cggtccaaat ggtgctggaa agtcaacggt gttgtcgatg atcagtcgtt tgataccaaa
    45181 agatacaggt gaaatctatt tagaccataa cgaagtaaag gcttggaaat ccaatgaatt
    45241 agccaaaaaa ttatcgatcc tacgacaatc gaatgaaata aatgtccaaa tcaccgtgaa
    45301 agaattagta gaatttggac gatttcctta tacgaaagga aaattgacga caaaagacga
    45361 ggaaatcgtt caggaatcac tggaacacct tgggttagaa gaaatagcgg atcaatcgat
    45421 tgacactctt tcaggcggtc aactccaacg tgcgtatatt gcaatggtgc tagcgcaaga
    45481 cacggattat attttactgg atgaaccttt gaacaatcta gatatgaatt ttgcggttca
    45541 aatcatgcag attttaaaaa atttagtaca agaaatcggg aaaacaattg ttattgttct
    45601 tcatgatatc aactttgctg caagttatgc agacgaaatt gttgcaatga aagatggaca
    45661 gttatttacg caaggaacga cccaagaaat gataaaaaaa gatgtattgg atgaattata
    45721 cgaaatggac atacggattt gtgagattga aggccgcaga ttctgtcttt atttctaaaa
    45781 ctaacattag gagagaagag atgaaaaaat tagtagtagg tatcttgatt ctagcatcat
    45841 ttggtttagc agcatgtgga aatagcaaca acaccagtca ggcagacaca aaaaaaagca
    45901 gcacacaaac tgaaactaca ttgacgataa cagatagtaa tggagaccaa atcgaggtgc
    45961 caaataatcc agaaaaagtc gtcgtattcg acaatggttc tttagatacg atggatgctc
    46021 ttggtgttgg agataaggta gttggagcag ctacaagcag ccttcctgag tatctttcat
    46081 cctataaaaa agtagaatca gcaggtggaa taaaagaacc agacttagaa aaaattaatc
    46141 agcttcagcc agatctaatc atcatttctg gccgacaaag agattttcaa aaagatctaa
    46201 gtcaaattgc tccgaccatt ttcctttctt tagatgcgaa aaatccatgg gaatctttcc
    46261 agcaaaatgt cactgcttta ggggagatct ttggtaagca agaagaagct aaaactcaat
    46321 tagaggaatt atctagtgca atcgatcaga cgaaaaagaa agcagaagct actgacaaaa
    46381 aagcactagt cacacttgtg aatgaagggc aattatcagc ctacggatct ggttctagat
    46441 tcggtttcat ccatgattta tttggctttg aacaagcaga tgatcaaatc gaagcatcca
    46501 ctcacggtca aagtgtttct tatgaatatg tgctggaaaa aaatccggat atcttatttg
    46561 tagtagacag aacaaaagct attggtggag acgacagcaa agatgatatt tctgccaatg
    46621 aactggtagc acaaacgaat gctggtaaaa atcagcagat catctccctt gaaccagatg
    46681 tctggtattt aagcgggggc ggtttagaat caatgaaact gatgatcgaa gatgtgaatc
    46741 aagcatttaa atagcataaa taacagagga ttaaactctc atactatgta acaataatgt
    46801 ttcttacatt cttaaatagc aagagcctat cctcaaagaa gttatcaaaa accatccgta
    46861 aaatcgtatt gatgatttta cggatggttt ttatttattt gagaaatctt ttttcaacgt
    46921 gaattcatta tctacatcat acgggttgat tctagaatgg ggagtggcaa aaaatagtgt
    46981 gatccatttt ttcagcatca agatcgcctc ctttgatttg aatcaaaggt acaaagcgaa
    47041 acttagataa aacttaaatt tagatatttt tattttgtac cgatctcttc tttaaacgat
    47101 gttccatctg ctgcttctcg gcaataagtc cactagacta gaaaatatga gaagctattt
    47161 tctgtccagc gttcttatta ctcaaagcaa atcgcagttg tcacaatctc ttctaaacga
    47221 tgttccatct gctgcttctc ggcaataagc ccactagact agaaaatatg agaagctatt
    47281 ttctgtccag cgttcttatt actcaaagca aatcgcagtt gtcacaatct cttctaaaca
    47341 atgttcaatc agctgacctt cggtattagc tcaaagcact gatttcacaa cctctattta
    47401 ggcatgtgtc tcagcaagcg gttgatagtt gatgatctgc atttttcgat aaaaatcggc
    47461 gggaagctta ctccaccgtt ttaataattg atagaaataa ctctcttctg ctttgatttt
    47521 atactcgctt aatatcaatc caaaactatt cgtttttttt gaagctaatt ttttataaat
    47581 atccaatgct ttggttttat cttcattgac aaagagtgtt tttacttcaa tataagaacc
    47641 ctcgatattt tgtgtttctt cgataaaata gatgtttttt atatattcct tcatagtgat
    47701 tcctccaaag aagtctttta tttgataagt ttactctacc gaagagttgt taataatccg
    47761 tgaacaaaaa gtaattcttt ttccaatagt tgttaaaggt tttttatttt ttatagtatt
    47821 ttttgttatt taagaaagga ataaggttaa acaaataaca ggttgctttt tgggtctttt
    47881 tccgttcaag aaactgaacg aagaaaaggg aaagttgtct cttttgtgat aagagaaatc
    47941 ataataaacg aatgacttac tttccaataa attgagaaca gtcagaacca gacaaattag
    48001 ttgcatctga tgaataaagt gattattcta tgacatgagg tgatacagat gaaattagaa
    48061 gtgacaaaag aagcacaaga agtattgaag aataaattag aagcagacga tcaactttta
    48121 ttagatatcg aaaacggtga cggtccattt gcagaaagcc aagtcagttg ccaattggat
    48181 acggcatttc gattgatcat tgtcaaaaaa gatacacaaa cagatctaag tctttattct
    48241 gtagtggctg atacaccagt tggaccaatc aaaatcaaag acagtgcaat actttacatg
    48301 gatgatccat ccacacttgc tttagaacca acttataata gtttacaatt aaaaggacca
    48361 agcggcttga gaaaaggcaa cttgcaagtt gttcgaaaag actagaggga taaaatggga
    48421 aaattggcga tcatcagcga cctacatgtg gacatcaata aattcggcga atcagagctg
    48481 atgcagcttt ggcaagtttt gcaaaagcac aagatcactc ggcttcatct agccggagat
    48541 acggctaata aagtagaccg ttgcctagct gttgtcgaat ttttcgtcaa taaaggatta
    48601 tctacgacat ttcatttcgg caatcacgag ttggcagatg tgcccaatga acagatgatg
    48661 gaccattttc cagacccaca ttttttaaat gaacggtata ttgctttaaa tgagcagacc
    48721 gttcttttag ggatgaatgg ctggtacgac tatcagtttt ccgaattgaa agattacgag
    48781 gcaatcgtac gaatgaagcg tttgtattgg tatgatcggt tcatccagcg tgggaaaaca
    48841 gatctcgagg tcaatgcaga aatgcttgca gctgcaaaaa atttgctaga ccagctggaa
    48901 gcaaaaaaac ttgaggtgat tttatccact catttcgttc ctaaacgggc atttatcatg
    48961 tatcaatctg ctccttatga gcgttggaac aaattaaatg catttttagg atcagaatca
    49021 ttcggagaat tacttgaccg ttattcaaat atcaaacaag tagtttttgg ccatacgcat
    49081 cgtcgctttg aagataaatc catcggtcac acgatttaca gctgcagacc ttttggttat
    49141 tattatgaat ggcagctgac ccgagatttt gtcttgaaag aacagttgct agacagctat
    49201 gatcctatga aattacgtgt cctcttgcgt gcccatcacc cagcttttca ggcctatcaa
    49261 acacaacatt tgcaagagga atttgaacaa gcgatgacaa tcgttccgta ttgagacagc
    49321 attagtaatg tgtaaaagaa aataccttgt aaaacataag gataagtaag agcagtagat
    49381 ccatttatcg tggatatgct gctttttttg cggaaaataa tcagcgaatg tttatttgat
    49441 cggatgattt gtaactcgca gagtactaga tgcaagcgtg tattcttttt ttgaacgata
    49501 atcacaaaaa aaatataata tacatttttt atttaattat aattaatatt gattgaagtc
    49561 taggcagtca agtcacattt tgatagatag gagggggact tacgaattat tttaaaggct
    49621 atgacagctg tatttctaga ttgtgtttgc atcaagttgc aataaaaact agaaatcaaa
    49681 tcgggctgat aatcatttat aactaatcga tacataggac caaatatagg tctatgttct
    49741 tttatttcat aagtatcgta aaacagaatt ttgctatgga ttaatccaat cgactgatat
    49801 gtttagtaaa taaagaaaga ggaatgtcaa tgatgaaaaa agaaatcgta ttaacagcag
    49861 caataatgtt attcagcatg gtagcaagta cgacttttgt ttctgcaact gaagtatacc
    49921 caaaggaata taacacagaa ggaacgatta catttgaagc aggagatgag ggtgtaactc
    49981 ctcctgttga tccagagaat cctgatccca ataaacctgt cgatccatca gatcctccaa
    50041 gccctggaac aggaggggca ttatcgattg attatggatc aaaattcaaa tttgggactc
    50101 aaaaaatttc tactgcggat aaaacgtatt atgcagctgc tgatgtgatg aacgatgggt
    50161 ctagaaaacc gacatatgtc caagtgacag ataggagaag taccttatct gggtggaaat
    50221 taagtgtctc tcaaccagaa cagtttaaaa ctgccagtgg ggatgaacta gttggagcac
    50281 agctgaaatt tacgaaaggg caggctgttt ctttggttga tccaacatat acgccgcaaa
    50341 cggtgaattc tgaattaacg ttgacaccgg gaggaaacaa tacgttagca attaatgcta
    50401 aatcaggaac aggtgtgggg acttgggtct atcgatttgg tgcaaatgaa aatgaaaatc
    50461 aagatgcggt acagctttcg gtacccggta aatctgtcaa gttagcgcaa caatattcca
    50521 ctaaattagt ttggacatta gaagatacac ctaacaacta gtttactgaa aagaactgtt
    50581 aaaaataaat acgtagtcat attgtcttgc gaggtaatcg agcaaaaatt gtcaaaggct
    50641 aggctaaatt tgtttggata cgaatagttc atctaggaat ttaacgatca ggaggaaaag
    50701 atatattgaa aaagaggagg atcgtgctca ttttaagcag tctcttagtg actaatatct
    50761 ttccgatcat agggtactct ttggaattga atcagttgga gcatggaaat agaagagacg
    50821 aagaaagcaa actcacttcg acattcgaca gtttaataga atccaaccag acacaagaaa
    50881 gcagtgagga tttaagtatt tcgagtagtg gagagaccac tgacaacgta gaagctgagg
    50941 gttcggacaa acaaggacta gaagatgcac caatttctgc ggttgagctg cctgacgatc
    51001 ccaatattat ttctatcgat aaaatttttc aaacacctat cggtactagc acgtccatat
    51061 tggaaaatgg gaagttactg cagttgaacc cagcagaaag gtctcaaaga ggagctattt
    51121 ggtcaaataa gaagattagt ttactctcgg attttacatt taaatcttat ttatacttag
    51181 gaaatcaacg agatagagcg ggagatggca tgacctttac attgactggc gatcctagaa
    51241 tggctagtaa tcccagtcaa gttattggat cgccaggtat gggaattggc tcatattcta
    51301 ctcgttctgg ccaaccttac attgcgaatg cgctctcgat tgagtttgat acgtataaaa
    51361 atagtggttc ttctgatcga atggatcgag agataactgc tgataataga gggcatggac
    51421 atgtcgcttt tgtcacgcct aaaccaaata ataataatta ttctggagag catactggcg
    51481 tgacggtagc tcctacattt ctttctaatg gcacatggcg cttgttaata attaaatggg
    51541 acgcggagca aagaagtctt acttatgatt tggaaggtgt cggtcgctct tctcggatta
    51601 tacctgatct cattaggcag tttggttcta cagaagtaaa ttgggggttt acttcttcaa
    51661 caggtacttt ttttcaagaa aatgctgtcg ctgtcacgcg acttccatcg aatgtcacat
    51721 caacagctga tgtaaaagtc aacgatagtg attatggggc catcgctgaa gctggaggaa
    51781 acgataagat aactatcaga aatacattga aggtcgaggg ggattttctt gaatataaga
    51841 aaatgcagac tagtatcgac ctcccacaag aattaactat tcccgagcat atcttgatca
    51901 atggaaatca aattgatgcc aaagatatct tgataaccgg aaatcgagtc acgctaaatc
    51961 tgacagatta ttttattgct ggagatacgt taataatcga attggagaca actttgcagg
    52021 aagtaattcc tgaaaaagta ctcactatgc attttgaata ccttgaaaac gggaatttga
    52081 ttgagcaatc gaatgaaata aacctaaaga tcgcaaagct gaaggagata gatatccatg
    52141 tttattataa agataaagac agtcagattg atattgctga aatgaaaaca atcactggga
    52201 aaataggaga gaagtataaa gaaactccta ttgatattga agggtatgtt tttgactcgg
    52261 attcagcgaa tacagaaggc atcttctccg aaaatacaga ggatatctat ttttattaca
    52321 gaaaaggcaa actttatctc tcaactgctc ctcaatatgt caattttgga aaacataaaa
    52381 tatccagtag accattaagt gaattcggac agttttcagg tgggttgaaa attatagatg
    52441 aacgggcttt tggaagttgg aaattacaat tgaaacaaga gaaagttctt acaaatggag
    52501 attttgagct tccagaagct ctttcctttg ttacctctga aaatacaacg gttataggga
    52561 catccgctgt tacgattttc gaaagtgatc aaaagggtga aagcgatttg tcctctcttt
    52621 tagattctac agctcatcgt ggaatcagaa tagatattcc tgtagaaaac caaagaatcg
    52681 gaacctttga ggggaaacta tcttggatac ttgcagatgt cccaggaaat taacaggaag
    52741 agaagaatat aacaaaatta ttgagtttca agaagggcac aggtaccata ggctcttgtg
    52801 tcccacagag acaagatttt gttatagtct tctcttacat atgattaaag gagcgatttt
    52861 cttgagacca aaacaacaat tatttataac actcctagtt attttagggg cactttttaa
    52921 caatatatca gtgtcagcta gtgcatttaa tttttcagtg acgccgataa cttcagagaa
    52981 tcaaatcgac aagagaaaaa cttacttcga tcttcaactt gatccggatc aggaagtaga
    53041 agtaaaagcg gaattgagaa atgatacaga aaaagaagtg aaaatcgata tttctgtgaa
    53101 tagcgcaacc accaattcaa atgtgatggt tgaatacgga aaaaacgaga ttgaaaaaga
    53161 catgagcctg atctttgatc tggtagatta tgtgagctat ccacagatag tgacgctaaa
    53221 acctaaaagt gtccaaaccg ttgcttttca tgtcaggatg ccgaatgagc gatttgatgg
    53281 tgtattggct ggtgggatca cattccaaga aatccagacg gaaaaggacc aaacagaaac
    53341 taaggatcaa agcttatcga ttgagaatga atacacctat attattgctt tgttgatgca
    53401 acagacactg aacgaagttg ctccgaacct tactcttcat gaagttaaac cagatcaaat
    53461 caatgcaaga aatgtcatct tagcaaacgt tcaaaatgat caaaaaacct atatcaatca
    53521 agtagttatt gaaacaaaaa ttacaaaaaa aggacattct gaagttttat atcaagagga
    53581 aaaagaagga ttgcagattg cgccgaatac aaatttttct tttccaactg ctttaaatgg
    53641 tcaaccgcta accccaggtg aatatcacct tacaatgact gttttaggaa atgaaaatga
    53701 aaatggaaaa ttttcgagaa aaaaaggaaa tactacgatc aactatacca atcaatgggt
    53761 atttgaaaaa gattttacaa tagacggaaa agtagccaag gaattgaaca cgacggatgt
    53821 tacgattaaa aaagacaata attggattta tatcttagta gcttcacttt tcttattgtt
    53881 tattttatta tgcatacttt tgtttgtttt gagaaaaaaa gaagagaaag aaaagtaagg
    53941 ttaagataac aaatagtaaa tttttattat tgtaggatgg ttgggctctt tttataacaa
    54001 tataaaatat accattttat taataaaaat gcatactagt aaatgatata attctaataa
    54061 caggtttgat cgcgagaaag gccaaataaa acgctctcca aaatgttaaa aaaaagacag
    54121 gacgatgtat attatacaaa caagaatcgc tgacaacagt gactcggatc caggaaatca
    54181 gttttatccc cagctagttg gtgaatgcat ggaaagtaat atacgtagaa agagctgatg
    54241 actaatgaat tatgagtttt ttttaagcaa agaagatcac agaagttatt cattacttaa
    54301 atatttagaa gcaagctcaa atttatcaga gtcaatatcg aatgttcaag aagagttgtc
    54361 gctatcgaca tttctcttga aaaaaacgat cgataagctg aaacatgatt tacaaaagtt
    54421 cgatctagag aaaaatttgc gagtaaccgt cagtgaattg gatatatgtc tggaaattaa
    54481 tggaaaatgt tctagcaaag ctctgttatc tcgttatata acggattctt tatctatgaa
    54541 aatggtattg gctttctttc aggaaaaata tatctcagta gaaaattttg ctaaacagca
    54601 tcacgtgagt tattctgtgg cttataaagt attacaaaga ctaaaaagaa atctaaaaaa
    54661 atatcaaatt ttttttgaaa agagaaagtt g
//
LOCUS       DAPBCF010000016        51122 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.016, whole genome shotgun sequence.
ACCESSION   DAPBCF010000016 DAPBCF010000000
VERSION     DAPBCF010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 51122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51122
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.016"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(19..294)
                     /locus_tag="RD508_001167"
     CDS             complement(19..294)
                     /locus_tag="RD508_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735778.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            588..1403
                     /gene="thiD"
                     /locus_tag="RD508_001168"
     CDS             588..1403
                     /gene="thiD"
                     /locus_tag="RD508_001168"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDT7735779.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKDAQQETVNDYVLLESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1608..3059)
                     /gene="cls"
                     /locus_tag="RD508_001169"
     CDS             complement(1608..3059)
                     /gene="cls"
                     /locus_tag="RD508_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDT7735780.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQKALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3401..6067
                     /locus_tag="RD508_001170"
     CDS             3401..6067
                     /locus_tag="RD508_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7735781.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNE
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6431..7183
                     /locus_tag="RD508_001171"
     CDS             6431..7183
                     /locus_tag="RD508_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7735782.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(7205..8359)
                     /locus_tag="RD508_001172"
     CDS             complement(7205..8359)
                     /locus_tag="RD508_001172"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HDT7735783.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8544..10985
                     /locus_tag="RD508_001173"
     CDS             8544..10985
                     /locus_tag="RD508_001173"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HDT7735784.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKPYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     KVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(11315..12019)
                     /locus_tag="RD508_001174"
     CDS             complement(11315..12019)
                     /locus_tag="RD508_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735785.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(12206..12451)
                     /locus_tag="RD508_001175"
     CDS             complement(12206..12451)
                     /locus_tag="RD508_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735786.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(12468..13319)
                     /locus_tag="RD508_001176"
     CDS             complement(12468..13319)
                     /locus_tag="RD508_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7735787.1"
                     /translation="MNSLTSTYRLLNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQPTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            13485..14489
                     /locus_tag="RD508_001177"
     CDS             13485..14489
                     /locus_tag="RD508_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDT7735788.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(14730..15086)
                     /locus_tag="RD508_001178"
     CDS             complement(14730..15086)
                     /locus_tag="RD508_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7735789.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            15454..16641
                     /gene="tuf"
                     /locus_tag="RD508_001179"
     CDS             15454..16641
                     /gene="tuf"
                     /locus_tag="RD508_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDT7735790.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(16829..19420)
                     /gene="mprF"
                     /locus_tag="RD508_001180"
     CDS             complement(16829..19420)
                     /gene="mprF"
                     /locus_tag="RD508_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HDT7735791.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLVSVLPMIGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDP
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(19446..20207)
                     /locus_tag="RD508_001181"
     CDS             complement(19446..20207)
                     /locus_tag="RD508_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7735792.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            20374..21006
                     /locus_tag="RD508_001182"
     CDS             20374..21006
                     /locus_tag="RD508_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HDT7735793.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMRSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            21065..21925
                     /locus_tag="RD508_001183"
     CDS             21065..21925
                     /locus_tag="RD508_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HDT7735794.1"
                     /translation="MEKRQKMENQKVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            22110..24425
                     /locus_tag="RD508_001184"
     CDS             22110..24425
                     /locus_tag="RD508_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7735795.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            24607..26448
                     /locus_tag="RD508_001185"
     CDS             24607..26448
                     /locus_tag="RD508_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDT7735796.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            26472..27581
                     /gene="rpoD"
                     /locus_tag="RD508_001186"
     CDS             26472..27581
                     /gene="rpoD"
                     /locus_tag="RD508_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDT7735797.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            27798..29939
                     /locus_tag="RD508_001187"
     CDS             27798..29939
                     /locus_tag="RD508_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HDT7735798.1"
                     /translation="MMKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDA
                     AMQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIE
                     KNEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHRED
                     TKEEHAKELLKMISEKIAQENKVEPEHEAEKDTEKDISGVNAAGKESLKTNDLKTNDL
                     KTDIPEKTETLSEKQSEDEKSNGLPEADKKEMLEKADKKATESDGINNEADAETQSAS
                     EDSTALEAKIEKEENQPELIEAETEPITIVPNTEKTPQESNPEKKDLDKTQKKKSKKV
                     PYLALAAVLLLGGGGWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFI
                     RADMIHQDLSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDH
                     LADDIKLKADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVV
                     DSATRDQYKTAKEAVEKVKNTDLSAQLNEQLQQVDKMLTDKEKKEEEEKKKAEEAKKA
                     EKAKKAAEEQAKQAAQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARAS
                     DIADASNPAWTWAPGVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKS
                     ALMKGIGESALPFYIVTINCKTGWFGGNGSN"
     gene            30135..30998
                     /locus_tag="RD508_001188"
     CDS             30135..30998
                     /locus_tag="RD508_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDT7735799.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            31103..31576
                     /locus_tag="RD508_001189"
     CDS             31103..31576
                     /locus_tag="RD508_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDT7735800.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            31672..32559
                     /gene="xerD"
                     /locus_tag="RD508_001190"
     CDS             31672..32559
                     /gene="xerD"
                     /locus_tag="RD508_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HDT7735801.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            32578..32949
                     /locus_tag="RD508_001191"
     CDS             32578..32949
                     /locus_tag="RD508_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDT7735802.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGVYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            32919..33716
                     /locus_tag="RD508_001192"
     CDS             32919..33716
                     /locus_tag="RD508_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HDT7735803.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            33700..34269
                     /gene="scpB"
                     /locus_tag="RD508_001193"
     CDS             33700..34269
                     /gene="scpB"
                     /locus_tag="RD508_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HDT7735804.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISFEEDVSPDLFFDGMNKGE"
     gene            34275..34991
                     /locus_tag="RD508_001194"
     CDS             34275..34991
                     /locus_tag="RD508_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDT7735805.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      35073..35197
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            35320..35931
                     /locus_tag="RD508_001195"
     CDS             35320..35931
                     /locus_tag="RD508_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7735806.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIP
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     gene            36309..37832
                     /locus_tag="RD508_001196"
     CDS             36309..37832
                     /locus_tag="RD508_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDT7735807.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            38069..39409
                     /locus_tag="RD508_001197"
     CDS             38069..39409
                     /locus_tag="RD508_001197"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HDT7735808.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            39563..40300
                     /locus_tag="RD508_001198"
     CDS             39563..40300
                     /locus_tag="RD508_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7735809.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGNSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(40465..40686)
                     /locus_tag="RD508_001199"
     CDS             complement(40465..40686)
                     /locus_tag="RD508_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDT7735810.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            40717..41748
                     /locus_tag="RD508_001200"
     CDS             40717..41748
                     /locus_tag="RD508_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7735811.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYERILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            41735..43138
                     /locus_tag="RD508_001201"
     CDS             41735..43138
                     /locus_tag="RD508_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HDT7735812.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGFLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVIHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKHQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            43204..43839
                     /locus_tag="RD508_001202"
     CDS             43204..43839
                     /locus_tag="RD508_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7735813.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            43888..44568
                     /locus_tag="RD508_001203"
     CDS             43888..44568
                     /locus_tag="RD508_001203"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDT7735814.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAIQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            44703..45932
                     /gene="rpsA"
                     /locus_tag="RD508_001204"
     CDS             44703..45932
                     /gene="rpsA"
                     /locus_tag="RD508_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HDT7735815.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            46114..47424
                     /gene="der"
                     /locus_tag="RD508_001205"
     CDS             46114..47424
                     /gene="der"
                     /locus_tag="RD508_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDT7735816.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            47667..47942
                     /locus_tag="RD508_001206"
     CDS             47667..47942
                     /locus_tag="RD508_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HDT7735817.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            48177..49223
                     /locus_tag="RD508_001207"
     CDS             48177..49223
                     /locus_tag="RD508_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735818.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQRPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            49225..50484
                     /locus_tag="RD508_001208"
     CDS             49225..50484
                     /locus_tag="RD508_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDT7735819.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIAPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            50490..51071
                     /locus_tag="RD508_001209"
     CDS             50490..51071
                     /locus_tag="RD508_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HDT7735820.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
BASE COUNT        17066 a         8837 c        10759 g        14460 t
ORIGIN      
        1 ataaagaaca gttagaagtt aaaattgctg attcacatag agtttatgac ttcttggaaa
       61 ttctttttca atcagttttt tcatctgttt atgaaattct tttttttcag taaacataaa
      121 ggtttgggta tcgtaacctt cttcatgtag gaaatagatt attccttttt ctgtgttttg
      181 cgtataagct tttatactcc tgtctttttt gaaagaacag atcgtatagc catctatttg
      241 gtctggtagt cgtttgattt tcttcaaaat gactttttta tcctcaagtt tcattttttt
      301 cacctgactt tatttttttc atatggaaat catagcgcct ttggttatat gaaaacaaga
      361 aggatactga aatatatata aatcaaatag tggttattta ttattagaat agcgaataca
      421 aacaaatgac aactattttc tgatttatta caaatgtttt ttcaaataaa tttgattacc
      481 aagaaaaggt agtggtatat ttactgaggg atactttgaa aaacatatga tagaaacagt
      541 aacagcatta tgaaaaatct ttttataaaa atggaggaat cgatttgatg gaagatcagt
      601 atgtacaagc aatgacgatc gcaggatcag atagcgatgg aagcgcaggg atgcaagcag
      661 atatgcatac attctttaca agaaatgttt acggtgtttc tgtcatgacc gcatgtgttg
      721 caggtaattc ttacggaatc ggagcaagtg tgacattgcc aacagatttt atcgacaaag
      781 aatttgaact gattgcgaag gactttcaaa tacgtgcagc taaaacaggt atgctagcag
      841 attcaaagtt gattgagaca gttgtaaaaa attaccaaaa atatgatttt ggaccattag
      901 tcgtggatcc cgtaatcgta acgaaacatg gaaatctttt actagaagaa tctgctttgc
      961 aaagcttgaa agaaaagctt gtccctttgg ccgaagtact gacacctaat ttttatgaag
     1021 cagaaaagct gactggacgg acattagcag ctgaagaaga ttttgtgcaa gcagcaaaag
     1081 aactgcaaga tatgggtgca aaaaacgtta tgatcaaagg acatcatgct aaagatgcgc
     1141 agcaagaaac agtcaatgac tacgtattgc tcgaatcagg aaaatcattt tggttaaatg
     1201 caccatttta tcctaccgac cggatcaacg gaactggcga ttcgctatct gcatgtattg
     1261 cagctgagtt agcgaaagga aaaacagttg aacaagcgat ccgattggca aaagactatg
     1321 taaaccgtgc aattcgtgaa gaaataaatg tagggcacaa atatggaccc atcaatcatt
     1381 gggcagctgg tgaattagag taaaagaaag aggtcgtgag cctgccgtcc agctccgagt
     1441 cacaaggaac aagttcaaaa aacagcttct catgtttgtt gaatattgtg acttgtgacc
     1501 gaggagttgg caggagaaca ccgtttgttc ggaagaaggg actgtgacaa gatttttgtc
     1561 acagtccctt taatcttagt atatttttct ctacttgaat aaaaaaatta taggattgga
     1621 gaaaataatc gagaaatttg ttgcttgaat aatagccagt tagacatttc cttgactgtt
     1681 tcagttgtca tggatgaaca atgtgtctca tcttctttga actgagtagc aagttcttct
     1741 aaaaactcag gatcgtaaat gacagcactt gtttcaaaat tcaatcggta gctacgaata
     1801 tcttgatttg ctgaacctac catgcagatt tcatcatcca ttatcaatgt ttttgcatgg
     1861 aggaagccgt tctcatagac aaggatttgt acattttcct tgatcagctg ccgagcataa
     1921 tattgtgttg ctcgataaat aaaaggatga tccggtttgt tgggaatcat gattttcaca
     1981 tctacaccag aggcagttgc gatttttaaa gcagcaatga cactttcatc aggaacaagg
     2041 taaggtgtct gtatccaaac acgtttttta gcagaagtaa tcaatttgat aaatgaaagc
     2101 ttgatttgtt ccctttcgtt attcggtccg cttgaaacaa gctggatgga tgtatcagca
     2161 agcttagatt catctcgatc tgctttttta aagaaataat tcaaatgata gccgaccttt
     2221 ttttcttcag gtaccgagac gttccagtct gttaagaagc gaagctggag caaagaagaa
     2281 gcggcaccga aaatccgtat atgcgtatcg cgccaatagc cgaatttttt tgttgtattt
     2341 acatattgat tggcaatatt gaaaccaccg gtataactaa tctttccatc gatcacaacg
     2401 atttttcggt gatcatggta attcaatcgg aaacgaagta atgccttttg tgaggtaaca
     2461 aatgtatgga catgtccacc atttttgatt agacgattga aatcttttgc ttttgtacca
     2521 tgagagccaa atgcatcata taatattcga acttccacgc cttctgcggc tttttcttct
     2581 aaaacatgta agacttgctg gccgatatta tctgtcacaa atgcgtaata ttcgatatgg
     2641 atcgaatgtt tggctttttt tagatcttga agcagtgaat ccaatttctc ttgtccgtct
     2701 gtgagaagag tgacagaatt cattcttgtc agcggcatac gatttaatga agagaagaag
     2761 tcgacaaatt gctgtttgtc tttatcgccc atgtcaggat cgtaatgttc aatggtatct
     2821 cctctaaaag actgaaagtt ttctaattct ttcaagtcac tttgtcggag atagaatttt
     2881 ttcttatccg ttaatccacg tccgaaaaat aaatataata caaagcccac cccaggaagg
     2941 gcaaacaata ctaagagcca tgcccaaatg gctgctacat ctcggggttt gatcaaaata
     3001 gccaccaaag caataagtgc atttaataga taaagggcgg ttataatact agataccaca
     3061 aaaatgttcc tccttacata caataacatt agtatagcat gatagaagaa agaagcctac
     3121 caaggtgaat atacttttca ctcctttcat gaaaatgtag gtaaatcggg ctaaagtagt
     3181 tgctttttgt aggttaataa ggtaggatat tagtacagtt gaatatctcc ttaggggagt
     3241 aaccggcaac gtttgttgcg ataatatcaa cagtaagtta accaaatggt tttctggtat
     3301 tgtatgaaat ggtgagacct aagacaaatg cgtatttgtc ttaggtctct ttttttttca
     3361 gacaggacta gggccaagat caaaaaatgg gggatgaaat ttggaaaaca aggaacaagc
     3421 acaacaagcg gtctataaag aaacgatcga ctcgttgatg cagcaaacgc agagctcaac
     3481 cgatggattg agcaccacgc aagcgaagga aaaattagaa agagatggct tgaaccagct
     3541 aaaagaaaag ccgaagaagc caacttggaa attgttctta gaaactttca aagatgcaat
     3601 ggttatcgta ttgctgattg tcgcactgat tcagatggtc atgggtgact acatcgaatt
     3661 cttagttatt tttgcagtat tgatgttgaa ttctataatc agtgttgtcc aaacaaaaaa
     3721 agcagaaggt tctttagaag cgttgaaaaa cctttcagcg cccgatgctc gagtgattcg
     3781 tgatggtaag gaaaaaacga ttccggcaaa cgaacttgtg gtaggagata tcgtgttgtt
     3841 agacgcaggc gattatgtac ctgctgatgg acgtttacta gatgcgggat cattaaaagt
     3901 agatgaaggt atgctgacag gagagtcgac ttctgcagaa aaagaagtaa cggatatcac
     3961 aagtacggta ccaatcggag atcgtacaaa tatggtattc agtggaacga tcgtaactta
     4021 cggacgcggt aaattcttag tgacttcaac tgggaataat acggagatcg gacaagttgc
     4081 tggccttttg gaatcaacaa ctgagcaagt cactccgtta caacgaggtc tggataaatt
     4141 cagtaaaaaa ctaagtctgg ctattttggc attgtcttta ttgattttag gtatccaact
     4201 gtttcgtatt tatcttggag aaggtacagg agatatgact gcagatatcg tcagcgcagt
     4261 gatgtttgcc gtagccgtag ccgtagctgc tattccagaa gcattacagt ctatcgtaac
     4321 aatcgtgtta tctttgggaa cgaataaaat ggcaaaacgt catgccatta ttcggaagct
     4381 tccagcagtt gaaacacttg gttcgacaag tatcatctgt acagataaga ctggtacatt
     4441 gacacaaaac aaaatgacag ttgttgacta ctttttaggt aatggcgata ctggggattt
     4501 cacaaatgac ccttcaaaat ggacagctga cgaacgtcgc ttgatcgaaa tcagtgtttt
     4561 agcgaatgat gcatcgatca gtgaagacgg tactaaattg ggcgacccta cggaagtagc
     4621 gtttatcgac tttagtgaaa aattaaacca gccttatcag gaaatccgaa acaactaccc
     4681 aagacaagca gaacttcctt tcgattctga tcgaaaatta atgtctactg gacacacgat
     4741 cgataacgaa aattacttgt ttgtcaaagg cggaccagat atcgtcttcc aacgcagtaa
     4801 aaaagtattg ctaaatggtg aagtcgttcc gatgacggat gaattgatga aaaaattcca
     4861 agagcaaaat gaagcttttt caacacgcgc attacgtgta ctagcttttg cttaccgtcc
     4921 acttgataat tttgatttat catttgaaga tgaagacgat ttgatccttg ttggtttgct
     4981 tgctatgatc gatcctccac gtgctgaagt gactcaggcg gtaacagaag caagaagtgc
     5041 aggaatcaaa acaatcatga ttactggtga ccacaaaaca acagctgttg ctatcgcaaa
     5101 acaaatcggg atttttgaag aaggaaacct ggctttgacc gggacggaac tagatgaatt
     5161 gacagaagat caactaaacg aagttttaga aaaagtcact gtttatgcac gtgtttcacc
     5221 tgagaataaa attcgtatcg ttcgtgcttg gcaaaataaa ggtcatatct cagctatgac
     5281 aggtgatggt gtaaatgacg caccagcatt gaaacaagca gacatcggaa ttgctatggg
     5341 aacgggtaca gatgtggcaa aagatgcagc agcgatggta ttgacggatg ataactttgc
     5401 ttctattgtc agcgcagtag aagtaggacg taatgtgttt gataatatca agaaagctat
     5461 ttcttatcta tttgcaggaa atttaggtgc gatcattgcg atcatctttg ccttagttgc
     5521 tgactggtcc aatccattta cagcattaca actgttgttc atcaatttag tcaatgattc
     5581 actgccagca attgcattag gtacagaaaa agctgaacct gctacgatga accgcccgcc
     5641 aagagatcca aattcaggaa tctttacgga caaaacattg atttctgtaa cgtatcgtgg
     5701 tgtgctgatt gggattgctg ttatctttgc tcaatggctt ggcatgcagc attcacctga
     5761 attcggtgta gccatgtcat tttcaacatt gatttggtgt cggacattgc aaacattccc
     5821 agcacgttca aacacacaaa cagctatcca agcagggttc ttctctaaca gaagtgtctt
     5881 actagctgta gttgtatgta gcgcgcttta ctgcttaaca atgatcccag gactgaaaga
     5941 agtcttctct atcccatcag catttggatt gacagaagtc tttacatgta tgggaatcgc
     6001 acttgtgaca attgttttga tggaaatcac taaattgatc attgtacgag tacaaggaaa
     6061 taaataaaac gaatcaacga ggttgtgagc ctgccgttta attctgagtc acaaggtgca
     6121 atttcaacaa acagcttctc atgtttgttg aatattgtga cttgtgaccg aagagttggc
     6181 aggagaacac cgtttaagga agaagttgta aaatcagcat tttgagctaa tactgagggt
     6241 catctgattg gacactgttt attcggaaag agggactttg acacgacttt ggtcacagtc
     6301 ccttttttta tttatgatag acggaaagcc aatcatttta ttattcatca aaagagatag
     6361 aatagataaa agaggagaat aatttattcc gaaaagtgaa aacatataac aaaaaattag
     6421 aggaaatcaa atgaatgaaa aagaatggga tgaatttgct gaagaatatt atgaaatcca
     6481 gcaagaatcg caagtaacta ttgctgaaga tgtaaaaaat tatctgaaaa cggagaaagt
     6541 cctgcctgct gaaacagcag cagacgttgc tggaggatct ggcagatttc tttccttagc
     6601 aaaagaaatt aatcgctatg atttgatcga tttttcttca ggaatgctag aaaatgcaaa
     6661 aaaagaagca gaaaaaaatg agttgccaaa tgtttccttt atcaaacagt cgttagaaga
     6721 atttatccaa tcaaatgaga catatgaaat ggtttttaca gcagcaaatc cagcattggt
     6781 acatcttatt caattagaaa aattgatgaa aaagtcaagc aaatggtgcg tgataatcag
     6841 ggtagtggaa tcaatcgatg atgtttttta tcctatcgaa aagcaactag gaatgataga
     6901 agaagatcct aatacatcgc cagttgtaat ggatcaattt gaaacatact taattgatga
     6961 aggattcaaa gtgaagaaaa aagattttac ttattttaca caggaatcaa ttactgaaga
     7021 attgatgaag ctatactatg acgcgtacgc aaaagatcct gttgtgacca ggtacattcg
     7081 caaactattc agtgaaaaac gagaaatcct tagtacgact aagctgacct atagactgct
     7141 cctttggtcc gcagataaaa aaagaacctt tcacgactcg tgaagggttc tttttatgat
     7201 tttattatat tttgtagtaa cgaatatcat tttcgatctt tgtaatcgaa aaaggtacat
     7261 ctgaagtata ttctgcacat tctccgtgtt caggaagcgt ctcactgaaa atcgtttcat
     7321 attcgtcaac agtgatccgt gttcgagaat ctagcatctc ttgatgagat tgtgcgaaga
     7381 gatattcttg atagttttct tccagataac ctgtaaaaaa ttcacttact gcaccagaac
     7441 cgtagctgaa tagaccgatg cgatctcctg gctgtagtga tttcgaattt tccagtagag
     7501 aagttagccc caggtataat gaaccagtgt aaagattacc gattcgtcgg ctgtaacgga
     7561 tgctttcttc atagcgagcc ataagacgtt cctgattttc ttcgtctgtt tggtctaata
     7621 cgctttgcaa tgcctttttt cccatcttag tatacggaat atggaaagca atcgcctgat
     7681 aatcttcgag tcctcgaccc gacaattctt tatgtcgatt ccaaactttt tggaatgatt
     7741 cgatatacgt agaattagat aaaggaccat caacaacagg aaattcgcta taatctggac
     7801 gccagaaatc atagatatct tctgtcagaa atacgctgtc gtcttcaatc gataaaatac
     7861 gcgggttttg agtgatcatc atcgcaacag caccgacacc ttgcgtcact tcaccaccgc
     7921 ttgccaagcc gtaacgagca atatcacttg ctatgactag tacttttcgt tctggatgat
     7981 ttttgacata ttctttcgcc atgtgcaaag ctgcggtgcc accgtagcaa gcctctttta
     8041 cttcaaaaga acgagcaaaa gattggattt tcagtaaatg gtggataatt accgcactcg
     8101 cttttgaatg atcaatcccg gattctgttc cgacgatgac catgtcgatt agctcacggt
     8161 ctttttctgt tacgattttg ctggcagcat ttgctcctag tgtaatgatg tcttcatttg
     8221 cacgattgac tgccatttgg tcttgaccaa tccctatatg gtattttgca ggatcatccc
     8281 cacggctttc tgccaactct gtcatatcta aatataaatt aggaataaaa aaggaaagac
     8341 gatcaatccc tattttcatt tcaacacctc tttacttatg ataaaaaact tactttacta
     8401 aggtatcata aaaagattaa aagaaatata aaaaagagaa tatttaagga ttgttaaaat
     8461 ttaatcttag aaaaaaacaa ctggaacaag agctatttgt ttttacagca aagaatggta
     8521 tatttttgta ggaggtggct tacttgaaag aagtcgttat gatagatgct gcaagaacgc
     8581 cgataggaaa gtatcgcgga agtttaagtc catttactgc agttgaatta ggcacacttg
     8641 tgactaaagg attattagat aaaacaaaac tgaaaaaaga taaaatcgat caagtaatat
     8701 tcggaaatgt cctgcaagct ggtaatggtc aaaatgttgc cagacagatt gctttgaaca
     8761 gcggtctccc tgtagatgtc ccagcaatga cgatcaatga agtttgcgga tctggtatga
     8821 aagcagtgat cttagcacgc cagctgatcc aattaggtga agcagaactt gtgatagccg
     8881 gcggaacaga gagtatgtct caagcaccta tgctgaaacc gtatcagtca gaaacaaatg
     8941 aatatggtga accaatttcc agtatggtca acgacggatt gactgacgca ttttcaaatg
     9001 cacatatggg attaaccgca gagaaggttg caacacaatt ttctgtgagc agagaagaac
     9061 aggatcgcta tgccttgtcg tcccagttga aagcagcaca tgctgtcgaa gccggtgtat
     9121 tttctgagga gatcatccca gtcaagattt ctgatgaaga cgtgttatct gaggatgaag
     9181 cagttcgtgg aaatagtaca ttggaaaaac tgggcacgtt acgtacagta ttctcagaag
     9241 aaggaactgt aacagcagga aatgcttcgc cattgaatga cggtgcctct gtggtgatcc
     9301 ttgcatccaa agaatacgca gaaaataata atctgcctta tttagcaacc atcaaagaag
     9361 tagcggaggt cggtattgac ccaagtatca tgggaatcgc tccaatcaaa gccattcaaa
     9421 aattgacaga tagatcagga atgaatttat caacaatcga tctttttgag atcaatgaag
     9481 catttgcagc ttcttctatc gtagttagcc aagaactgca gttagatgaa gaaaaggtca
     9541 atatatatgg aggagcaatc gcattaggcc atccaattgg tgcaagcggt gcacgtatct
     9601 tgactacatt agcttacgga ttgcttcgtg aacagaagag atacggtatt gcttcattat
     9661 gtattggtgg aggtttaggc ttggcagtct tgttagaagc gaatatggag caaacacata
     9721 aggatgtgca aaaaaaaaag ttttatcagc ttacgccatc tgaacggcgc agtcaattaa
     9781 tagaaaaaaa tgtattgaca caagaaactg cgttgatttt tcaggaacaa acactttctg
     9841 aagagctctc cgatcacatg atcgaaaacc aagtgagtga agtggaaatc ccaatgggca
     9901 tcgcgcagaa ttttcaaatc aatggtaaga aaaaatggat tccgatggca acagaggaac
     9961 catctgtcat tgcagctgca agtaatggtg caaaaatctg tggaaatatc tgcgcagaaa
    10021 cacctcagcg gctgatgcga gggcaaatcg ttctatcagg aaaatcggag tatcaagcag
    10081 tgatcaatgc agttaatcat cgaaaagaag agctgattct ttgtgcaaat gaaagttatc
    10141 cttcaatcgt gaaacgcggg ggcggtgttc aagatatctc tactcgggaa ttcatgggga
    10201 gtttccatgc atacttatct attgattttt tagtggatgt aaaagatgca atgggcgcta
    10261 acatgatcaa ctcgattctt gagagtgtgg caaacaagtt acgggagtgg ttccctgaag
    10321 aagagattct attcagtatt ttaagtaatt ttgctacaga atcattggct tctgcctgtt
    10381 gtgaaatccc attcgaacgc ttagggagaa acaaagaaat cggtgaacaa attgccaaaa
    10441 aaatccaaca ggcaggggaa tatgcgaagc ttgaccctta ccgtgcagca acgcacaaca
    10501 aagggatcat gaatggtata gaagctgtag tggcagctac aggaaatgat acacgtgcgg
    10561 ttagcgcttc gattcacgcc tacgcggcaa gaaatggatt ataccaagga ttaacagact
    10621 ggcagatcaa aggggataaa ctagttggaa aactaacggt gcctttggct gttgccacag
    10681 taggcggagc ttccaatatc ctgccaaaag caaaagcatc tttagctatg ttagatattg
    10741 attcagccaa ggaactagca caagtaattg ctgcagtagg gttagctcaa aacctggctg
    10801 ctttgcgtgc attagttaca gaaggaatcc aaaaaggcca catgggactt caagctcgtt
    10861 cattagcgat ctcaattggg gctattggtg aggaaatcga gcaagttgcg aaaaaattac
    10921 gtgaagcaga aaagatgaac cagcagacag ctatacaaat attggaaaaa atccgggaaa
    10981 aataaaaaag caatatcttt agaagaataa agcaagattt acagttattt tatttactgc
    11041 aaatcttgct tttttctcta tcagaaaata tgtttattat tagaattttt tatagttaag
    11101 gttaggcatc ttaagaaatc aggcaactcc aagatatctt caggtagaag agaagtcgcc
    11161 taacattgta ggatcatagg tgatttgttg gacaggtcaa gctgatattt gagcctgatg
    11221 ttagaaggaa tttcttttta cttgctgtag aaattattat atgactaaaa aggctgggat
    11281 tttaaatccc agccttttat gacaaataga atttttatcg atcagtaatc gctgtcgctg
    11341 caaattgttc gatcaaagga atcaaagtca atttgacttt gtatttccgt tcgagtgctt
    11401 tttcgataac gaactcattt tcagtagtca tagaaatagt tgctaattta cgaggttcat
    11461 cagcattttt ttcattaata actacttcat gttcattttg ttctgtgtaa aatttaggat
    11521 actcagcaac ggcttttgaa aaatcagcaa aacttaaagc ggcattcgta tcagttgagc
    11581 gtgtattttc agttgtgtcc gcttttggtt tttccgtttt ttcttctggc acactgactg
    11641 tttcttctgt aactggtgtc gcaacagctt gcgcagttgg ttcatcgttt ttcaatcgtt
    11701 gatcattcca gtaagacacg atttcaataa gaagattgtc acggaatcgt tcgaaaatcc
    11761 cgttttctcc tgaacgaatt ctctttaata cagtattgaa gttgtcatcg attggcacgt
    11821 tgatccgtgt atcttcattt gttttcccag ctaatccgat cgttaagatt tgacggtttt
    11881 tgggatcaag catgacttgt aacggcaaac catagcgtcg caagctctct tcttctagag
    11941 aacggaataa ttgtcctctt acaccatcca atgaaggacg gaattgattt aataattttt
    12001 gtttctgttt tttcttcata tgttctctcc ttcgctcata ccctttcgat tataagaaaa
    12061 aaacagccaa atgaaaagga gtaatgcaaa aaaacttgcg tatacgcaaa ttacaacaga
    12121 aaaatttgcg tattttcccg ttttttgaaa gaaaaataaa aaatggaacg gattatgtat
    12181 atatacataa tccgttccat tctttctatt ttttcggtat caaggcaaaa acaggtagtt
    12241 caggtgaata aatgacttca tgttcgtgcc agggtttgac cattagcgaa tgatcgaacc
    12301 gttttttcag ttcttcgatg atttgatcat gtgtccagtt tcttgcagga aaatgttgga
    12361 ttttctctgc atcgatcaaa aagacaaaat cggaatgaaa agtctgggta acttcttccg
    12421 agagagaatt caagcgttcg attggatcca taaaatcacc tttcgactta aaattgggta
    12481 gtatctgggt cttttgcttt gccgactaca ccatctaact gatcgatttg tttcatttct
    12541 tcttctgtta attcaaaatc aaataattca gtattttctt tgattctgct tggtgtcact
    12601 gacttaggaa gaggaaggaa ttcgtgttgc agcgaccaac gcaaagcaac ttgtgcaatc
    12661 gtcttgtcat gtgcttcagc gatttgtttc atttcaggca catcgaagat tttaccagtg
    12721 cctaatggac tatatgcttc gaggatcata tcatgttttt ttgcatactc aactacagtt
    12781 ggctgtaatt cgcctggtgc aaggaaaact tgattgacca tcggcataat ttttgctgtt
    12841 tttgctagtg tatctagatg gtggggtaag aaattgctca caccgattgc tttgatttta
    12901 cctgcttcat acagttcttc aaatgctcgc catgtatctg catttgcttg ttcccaatta
    12961 tcacgaaaag caacagggtt tggccagtgg atcaaaaaca gatctaaata atctgtttgg
    13021 agcttcttca atgattcttc aaaagaagac atcacaagtt catagctgtg gtttgcattc
    13081 cataattttg ttgtcaagaa tatctcttct ctaggaattc cactttcctt aatcgcttgg
    13141 ccgacacttt cttcattctt gtatccttgg gcagtatcga tatggcgata acctgcagcc
    13201 agcgcttctt taacagagga aacagcgaca tccccatcag gtgtttgcca tgtgccgaat
    13261 cctactaccg ggatttcgta accatttaat agacgataag tgcttgttaa tgaattcata
    13321 ctttcagctc cttttttatt cgttcaacta taagtgtagc gcatttttcg aaaaaaagaa
    13381 tccattttgt ttctactctt gaaatttttg tttaaaagaa aatgattttg attctggtat
    13441 ttttgatttt ttttccgtaa actaagacag aagggaatga gaaaatggat atctatttaa
    13501 aaaaagcaat tctgcatatt attgacagag aaactggttc tccagtcttt tcacaaaaag
    13561 agctggatct gacaaaagaa tatattcgtg attttcttca aaagaagatc caaaaaatct
    13621 cttctgctca aacaaaaact ggacaactag cagaagaaag catgatcgtt gaatcactta
    13681 aaatcgctca agaaaatttt gtggaagcaa gtgaagcaat cgttcagcgg tggttcgata
    13741 tctaccaaga aagtgaagaa gcacctagtg cagatgtatt tgttgttttg tatgaattag
    13801 atacagtgat gtacttatct ttattgaaag tcaattatcg tgaggcttac actcactttg
    13861 ttgaagcaga cgaagcaggg atcgacaacc gcttgatttt gaatcgagca attctagggg
    13921 cgaaaacaca aaaagcagat gaagcattcg ctgtgaattt gactgattgg acctacgaat
    13981 taattgaaaa aaaatatgag ttttctggca aaaaagagct ttatttttct ggaagagtga
    14041 tcgaaagtgt tcctgcacct tctttagaag aaaatgtaaa agtgatccaa aaagtagcca
    14101 agcatcttgg aaaaaaattt gagacagaag aatttgatat catggctgat ttgaaagaag
    14161 ctgtctatga tacgatagaa gaaaaaggtc ggttggatca tgagatgatt gcggaaaaag
    14221 tcttcaagga aaacatcacg gcaaaaatgg cttttaaaga agaagtacaa gagcaaggat
    14281 ttgtcccaga agcacctcct gtaaaagaag tacaagaaat ttctgagaaa aaatttggaa
    14341 aacaaaaatt caagctatca aacgggatcg aactgatcgt accagtagat gtatatcgca
    14401 acccagattt gattgaattt gtgaataatc cggatggtac gatatccgtg atgatcaaaa
    14461 atgtggatga agtattgaat cgtttataaa aatgactaga acattaggtg ttcaagtacc
    14521 agtgatcagt taaatgaatt gtgtcaagag aaggatcgga aaagacgaat ataacaaaaa
    14581 aagagcgtga gacaaaagta aagaacactt ttgtctcacg ctctaaacac gtataaacgg
    14641 cggaagcaga agcaactcct tcttatttct tggagttaaa cgcttctgtc ccagcctctt
    14701 tttatctaat aaaattttaa gaccatttac taattatcga ttttttctgc cgcattttta
    14761 ggcacttcag aagcctttat ttcttcccag cttaatacac ctttacgagg attgactttg
    14821 agtttaagat acgcattcat ctttaatgga tgttctcttt cttcgcgaag cgtcacctgt
    14881 tttttttcac catctttatt ataagccgct tgcttgtagg tataagtcgt gaatttctct
    14941 ccgttatctg cttgggtagc tgacatttcg ccattcgtcg tgatttttgt ataataagct
    15001 tcgccgccgt aaaaataatg ataagctgca aaacttccgc cgagaaatat gcctaaaacg
    15061 acaagtacgc caattaattt tttcatgtac ttcacctctt tccttattat taacgaaata
    15121 gaagatttcg tctattgaaa gttgttggca acagctgaat tttaaacttt tcctcatttt
    15181 gttcttattg cttcaaaaga aagttaagga ctatcttgaa gtttttctca aaaaacacat
    15241 ttttttattt ataaaaggta cttttttcgc gtataagaca agcgagtgct cttagttgac
    15301 tttgaccaat attgacgtat aataagctta gttcgaatct tacaaaaagt aagtcggacg
    15361 tattcttttt gatttagtca aaaaaagact ataataaaaa ggtgagagct gaaatttttc
    15421 agtgatctat attatttagg aggtttgtaa attatggcaa aagaacatta tgacagaagt
    15481 aaaccacacg ttaacattgg tacgattgga cacgttgacc atgggaaaac tactttaact
    15541 gctgcgatca ctacagtatt aggcaaaaaa ggcctagcaa atcctcaaga ctatgctagt
    15601 attgatgcag ctccagaaga acgtgaacgt gggattacga tcaataccgc acacgtagaa
    15661 tatgaaacag aaaaacgcca ctacgcgcat attgatgcac caggacacgc ggactatgtg
    15721 aaaaacatga ttacaggggc agcacaaatg gatggtgcaa tcttagttgt ttctgcaact
    15781 gacggtccga tgcctcaaac acgtgaacac attttattgt cacgccaagt tggtgtaaaa
    15841 tacctgattg ttttcttgaa caaagttgat ttagtcgatg atgaagaatt gatcgatttg
    15901 gtagaaatgg aagttcgcga gttattgagc gaatatggtt tcccaggcga tgacactcct
    15961 gtgatcaaag gttccgcatt aaaagcattg caaggcgatc cagatgctga agctgctatt
    16021 atggaattga tggatacagt agatgaatat atcccaacac cagaacgtga tacagataaa
    16081 ccattactat tgccagtgga agacgtcttc tcaattacag gtcgaggaac tgttgcctca
    16141 ggtcgtattg atcgtggtgc tgttcgtgtc ggtgatgagg tagagatcgt agggatcaaa
    16201 cctgaaacac aaaaagcagt tgtaacaggt gtagaaatgt tccgtaaaac gttagattac
    16261 ggggaagctg gggataacgt aggcgtgttg ttacggggga tccaacgtga cgatatcgaa
    16321 cgtggacaag tgcttgctaa accaggttcc attactccac atacaaaatt caaagcagaa
    16381 gtgtacgtgt tgacaaaaga agaaggtgga cgtcatactc cattcttcaa caactatcgt
    16441 ccacaattct acttccgcac aactgatgtt acaggaacaa tcacattgcc agaagataca
    16501 gaaatggtca tgcctggtga caacgtgacg attgatgttg acttgatcca tccaatcgct
    16561 gttgaaaacg gaacgacatt ctcaattcgt gaaggcggac ggacagtggg ttcaggtatc
    16621 gttacagaga tcgaagcata agaaacgcga ctcgaatatt ttggtaatga aaaatgttta
    16681 aaataaaaga gcggtccaaa caggatttct gtttggaccg ctctttgttc ttcaattgta
    16741 taagaagaga ttgtagaagc atgaactttc gttttacttc agtctctttt attcatcatg
    16801 agagtgttca tctatcggta tgcagttttt aatactttct tcgtatccat tttttcaaac
    16861 cacttattct accttgtgtc tgctcaactg gcgcattatc aataatcagc aaagcaatca
    16921 taacatatgc aatccaacta tctctagaat atagagtata acgtgagacc cagtttgtag
    16981 cgtacttgct tttatattct cttaatccat ggaaagaata aaaatgagaa ccaaactcgt
    17041 aaaccaagta tgcaatcctt tcctgtaaaa aactctttct ggaagttccg acatttgaaa
    17101 gaggggccat ccctaaattg aaccattgga tatgttcttc tttcatatag gcaaacaaat
    17161 gcaagaacaa gaaatccata ctgccagaag gtgctttttt aggatcatat cgcatcagat
    17221 caatcgttcc tactttattg ttcgtgtaag taggcatgat cgttgcaaaa gcgacaattt
    17281 cttcttgggt atttttgaca actgcaatag gcgctctttg tagataatct tcagagaaaa
    17341 agcctaaaga aaaccctttt tcctttcgtg aacccaacca attatcagag atatttttga
    17401 aagtactcat ttgctcagta gaaaatggtg gttgtaagac atcaaatgta aatccttctc
    17461 gttcgatccg attcaagaca gcacgagtgc ccttcatttt tttccctgaa gttgtaaaac
    17521 tattcaggtc tacataagct tcttccccca tcttaatgaa atcgtagccg aattcatgca
    17581 aaatcataac aatctcttcg cttgtttcgt agaaaactgg taaatagcat agtcgatctg
    17641 tttcttcgat aaaagcttcg attgcttctg gaaaatcttc tttcttacca gaaggatcac
    17701 ccattacaat acatttatta ttgaagcaag cgaattggag aagaacagtt ggttcaccgt
    17761 ctttttcata ggcaaacatc cgcttatctt ttaagaagat caattgacta tcggagtttc
    17821 ctccataagt tgtaaggatc ttcagggcct tttcttcatt aaaggcttcg ccaatctgtt
    17881 tcttttctcc ttgaaggaaa tgaacaaata gaacgatcat gaaactaaca gcgatgatgg
    17941 ccaacaatcc cgaaaaccaa atcttttcag aaggaaataa gaaaaaggaa ataaaatggt
    18001 gacgccgatg agggaaatcc ggcagattgt ataccccaat aacgatgtaa agcaaggaca
    18061 gtgcaccaat aatgattcca tcgatcgtac gccactccca tgaatagatc aattgttccc
    18121 gaaataattc gtttttagaa gcaagaatga tcagaagcag aatagacaag aaaaccaccg
    18181 gtgtgaaact aaaatcactt aataaaacat aaagtaaagc tagaacaatc aagaagattg
    18241 taggcaaata tgctcgtttc acacgtgctg cgatccctct gcccataatg attaaaagaa
    18301 atcccaatag tatactagga aattggataa taaaatgaaa tttcaatggg ttcaaactat
    18361 gaagccagcg aaactctgta aaagcttgcg ggatagtggc agaaagtact agcatgattc
    18421 cagaaaagta taataagaca accacgattt tatgcgcaat ttctgttgct aattgtttag
    18481 ggataccaga ataacgctga tcaaaagtgg aaccgatatt tttgaagaaa aagacgattc
    18541 caatcaaaaa cggaatgatg tagtagaaca ggcgatagag caagatccac acaacgacta
    18601 tttctcttgg cacaccaata gcggacaacc cgataatcat cattacatcg aaactcccaa
    18661 tttctcctgg aatcatagac acgattccta tcactgaagc agcaatgaat aacggaattg
    18721 tttgccacag atcaatccgg atttccatta aataaccaac agaaaggaaa ctaaacagga
    18781 caccggtcca ttccaacaat gaaactagca atagctgtcc ttgagtttta agtgaggtac
    18841 caccaaggaa tcctttcttt ttgaaagtag taaataaaaa gacgacagga aaatatagac
    18901 cgccgccgat caaccatatc caatattgct tcaaaaaagg agcaactggc gtgaagacta
    18961 caagtaaaaa agaaagcaga ctgtaaatag aaagtccagc catcaaaaac aagaaaactt
    19021 tcgataatgc ttggatcacg tttctgctct ctttcttttg tccatatagt tcagagcgaa
    19081 gccccacact aacaaacccg ccgaaaccgg caatattgtt gattgtattg atcagccagc
    19141 ttgtctcaaa caagtaacga ggattctgct tttgttcaag catccgattc aaaataatat
    19201 cataaccaat cataggtaac acagagacaa gaccaatcaa cagcataagt ccgcttttcc
    19261 atacaggtat agtggcaaac gtttctccta attgctggat agatagagtt ttaccgatgg
    19321 acatcaattc accgacaata atgacaatga cagaaatcaa aaagattgtt ttgaacagtc
    19381 ctaggtggtt tttcagccat tgtatggtat tttttaacaa ataaatcacc ttctattcct
    19441 aatagttatg tttcagaaag aaattgaaga acttctcgat tgaagcgttc aggatctttt
    19501 ctagctaatt catgtccttg ttctttcaca agcacaaagg aagcttttgg tatagtttta
    19561 gctatataca aagaatgttt tagcttgatt acatcttttt ttcccacgat gatcaaagtg
    19621 ggggagttga ttttttttaa atcattttct gtaagcccga tgtcatgcag caaaagtttg
    19681 ataactaaaa gatttttgcg aagacttggg cgaaataaag agagtaacca tacccatgca
    19741 taatgaatat tactgatgac tctggcagaa aaacgaacgc ctttaacaag cgtgtttcca
    19801 gaatttaaaa tcaatcgatg aactttttta gggaagctgc tggcaaatac cagtgctaga
    19861 tttgctccat cactaaatcc aagaaaatct gcctgatcga ttttttccag caacatgatc
    19921 gtattcagat cctcggccat taactgaaaa ttcaacatag atgcttcgtt tgtcgaacga
    19981 ccatgtcctc ggctatctac tagatacacg gtatagtagc gttcgagtac agggacctgt
    20041 tctgaaaaaa agcggccgct gccgtcattg ccatgcagta aaaagagagg gaagccttga
    20101 ccgctctttt catagtaaat ttcgctccca tctggcattt ttgcatattt cttttctttt
    20161 ttcacataat cacctactgt gtaaagtata acgattatat cagtcattgg gcaattgttt
    20221 ttactgaaaa acaacgatca ttttcgtaag atgacaaaaa atacaggaaa attcattttt
    20281 tcttaaggcg tacacagaaa tcaaggaaga aatagccaag aagataaaga aatagtaaga
    20341 taaaaaaaga tgtcaaaata actaggtgat gaaatgaagc gaaaacgatt atctattatc
    20401 cgtattcttt tttacatgat cattctgacg gttattggtg cggtgttgtt tttaggagga
    20461 agaacttatc gttcggtaaa acgagtggaa agctatcaaa tagaaataac aacagctgca
    20521 aaaaattatc atatggaaaa ctacgagaat ttgatcaagg cgataatatt gaccgaatca
    20581 aaaggaaaag ggacagatct catgcggagc tcggaaagtc tgcatggaga agctgagatc
    20641 attgataatc cagctgacag tattgatcaa ggtgtcaaat atttggcgga aatgatagta
    20701 gaagcaaaga aacaaggatg cgatttatgg acagctgtcc aagcatataa ttttgggaaa
    20761 gattatattg cctatgtaaa aaatcatggc ggagaaaaca cagtagaatt agcagaagcg
    20821 tattctaaag atgtgctgag cccactttta ggaaatgagg aagggaaaca ataccgatat
    20881 tggcggatcc agtccttgct ttacaatggc ggctatctct atcataatgg aggtaacatg
    20941 ttttatcctg atattgtcaa aatgaatgaa aaaataatag agacctatga aaaagttttt
    21001 aagtaaaata gcaggaaatg ttcaatcatg aataaaatta aatgaaagaa ggagtgcgca
    21061 aatagtggaa aaaaggcaaa aaatggaaaa tcaaaaagtg gggtacacaa ccaaagactg
    21121 gatgttacgg tttgtgaagg gaatgtttat cggttcagga tttatcttgc caggagtcag
    21181 cggtggtgca ttagcagctg tctttggcat gtatgagcgg ctgatttctt ttttagccca
    21241 ccttacaaaa aatttcaaag aaaatgtttt gttttttctg cctgttggtc taggcggagt
    21301 gacaggcatc tttctacttt cttttttagt cagtttttta ttaggtgcgt atgaaacaac
    21361 gatattatgg ttttttgtcg gatgtatcgc tggaactgtt cctgcgttat ggaaagaagc
    21421 agggaaaaaa ggaagagata cttctgatgt gatcatcatg gttgttactt ttgttctggc
    21481 ttatttgttt ttattatacg gcgctcaatt atttgacggg caagtcgatc agaattttgg
    21541 aacatggctg attgccggcg gattgattgg tttgggtatg atcgtcccag gattgagccc
    21601 ttctaatttt ttggtgtata tgggattgta taaagcgatg gctgacggat ttaaagaagt
    21661 acgacttgaa gtgattgtgc cgatcggaat tggtgggatt ctttgtgttc ttggattgtc
    21721 aaaaatcatg gattacattt tctcaaaggc atatagcaag ctattccatt tcattttagg
    21781 tgtagttttt gcttcaacga ttatgatcat tcctaccgat tacgcgggat tgggagttgc
    21841 tggggtacta gcttgtcctg ttctttttat agccggtaca gcactaggtt ggtggatgag
    21901 ccgtttggag gaacaatata agtaaagata gattgataat aaaaacagca cacgggtgat
    21961 tcaaacaaaa aggttggcat cttttttgta aaatcattcg tgtgtttttc tataaatttt
    22021 ataaaaacaa gttgttttta atcttggaac acgctagact taaacacgtg attatttttg
    22081 aaagttggcg gaaaatggag aaaaagaaaa tgaatggact tacacagcaa gaggtagttc
    22141 agaaaatggc ttctggccag caaaatgact accaggaaga tgcatcaaaa agtacaaaac
    22201 aaatattcag cgataatata ttgacgttat tcaattttct gaactttggt attgggattt
    22261 gtctgttatt tgtaggtgcg tattccaaca tggcgtattt agcaattatt gtcgtcaata
    22321 tcgttattgg aatttatcaa gaaatacatg caagaaatct tgtacggaaa ttatcgattg
    22381 tttcccaatc agaagtacta gtgatccggg acggtaaaga acaatcgatt tctactaaag
    22441 agctggtatt aggagatttg gtaaaaatcg gagcaggaga acagatacca gccgatttac
    22501 aggttatatc tggacgggca gaagcaaatg aagctctttt gacaggcgaa tctgatttga
    22561 ttgtcaaaga aactggagct gaattgcttt ctggaagctt tttgacaagc ggttctgtca
    22621 tggctgaagt tatccgagta ggtgcagata attatgctgt ccgcttgact agcgaggcaa
    22681 agactcacaa agctattcgt tctgaacttg tagattcgat tcgcaaagta tccaaattca
    22741 ctagtttcgt gattattcct ttggggatca tactattttt ggaagcactg ttcatccgcg
    22801 atgcttctat caaaatttct gttattgcat ctgcagcagc tttgttaggc atgcttccaa
    22861 agggtttggt attgctaata agtattgcat taacgacagg ggtaaccaaa ctggcaaaaa
    22921 aacgaatcct tgttcaagac atgtattcaa ttgaaacgct ggcccatgtc gatacattat
    22981 gcttggataa aacagggacc attactgaag gaaaaatgag tatccagcgg gtagaagcac
    23041 tacatccgct gtacgagaaa gccatcccag aaattatggg gacgtatctg gcagaaagca
    23101 gtgataacaa catcactatg cgggctatga gagattattt tgagctttct aatcggtatg
    23161 atgtgacaaa caaagtcgca ttttcttctg atcgcaaatg gggcgcgatg gaatttccag
    23221 aactgggagt cgtgtacgta ggagcgcctg aacgtttggt ggaagaagat cggcttccgg
    23281 acagtctaaa aacagcccaa gcgaatggct atcgcgtact tatgttaggg atcgctccaa
    23341 atcagcaatt gaacgaagaa aaaccagcat ttgttgagcc ggttgctctg tttgaaatcg
    23401 atgatccaat ccgaaaaaac gctcaagaaa cactagctta tcttcatgag gaaggtgtgg
    23461 atctgaaagt gatttctgga gacaatcctt ttactgtctc caatatcgct agacgtgcag
    23521 gattaccgaa ttatgatgcg tatgtcgatc tttctcaaat tactgaagaa atggaagtgc
    23581 gagaagctgc tcatcgctat acggtttttg gacgagtgag tcctcagcaa aagaaattgc
    23641 tggtaaatga attgaaagaa agcggcagaa cggttgcaat gacaggcgac ggtgtgaatg
    23701 atgttttggc gttaagagaa gcagattgta gcattgctat ggcagaaggt gatggagcaa
    23761 cacgtcagat tgcgaatctg gtattgttgg actctgattt tactacattg ccagaagtcc
    23821 tgtttgaagg acgccgagtg gtcaacaatg tgacgaaagt ctcaggcatc ttttttatca
    23881 aaacgattta ttcatttatt ttatcgatta tatgtgccgt tacagcaatt ggatttccgt
    23941 ttatccctat ccaaatcacg ctgattgatt tagcgattga agggtatcct tccttctttt
    24001 tatcttttga acaagataaa agaaaaatca cttaccgtta tttgcctaca gcacttatta
    24061 atgctttacc aaatgccttg cttgtagtag tgaatatcat tgcggtgtat ctacttggaa
    24121 aaacattcgc atggggaaat gctgaaacta ctactttgat gtattacttg ctgattggga
    24181 tcagttgcat ggcagttgta aaagcttgtt atcccttcaa cccattgcgc atcttcctag
    24241 cagtaacgac gatcgtaggg atatatgtag ctgcaatgct gttccatgga attttggaag
    24301 taaacttagg gttgggagag agcgtaggat acttctttgt attcatgctc gtaaatattg
    24361 ttcttcgagt attgtactgg aaggctgata ttcaaaatca gttactgaaa agagtagcaa
    24421 attgatgctt aatgagatag aaatgtgtta tacttgaaaa agcaatgaaa tatgatacaa
    24481 tcaaacatgt ataattgtgt cctttaaaat cgcactgatt tcagttagtg cgatttttta
    24541 ccggttattc tcctgaaata tcttctgtta aacccaaaag atatcaatag agcagggggt
    24601 ggaaaaatgg ctcaacggat tcctcaagag gttatcgaaa cagtacgcag tcaaacgaat
    24661 atcgttgagg tgattggaca atatgtccag ttgaaaaagt ctggtaaaaa ttacttgggg
    24721 ctgtgtcctt ttcatgaaga acgtacaccg tctttttctg ttgcagaaga caagcagatt
    24781 tttcattgct ttggttgtgg taagggcgga aacgtgttta cttttcttca agaactagaa
    24841 ggtctaagtt ttccagaagc agtggtaaaa gtggcagact tcgaacagat accgttagaa
    24901 gatcaatggc gtcagcgtac tatagctgtc caaaatcctg aatctgctac ggggaaactg
    24961 attgctgctc atgaaaaagc agcggaaatc tatcatcaca tgctattgca tacaaaagct
    25021 ggacagccag ctttagaata tttgcaaagt cgtgggttgt ctttagaatt aattgaagaa
    25081 ttcaacatag gttttgcacc taatgagcgt tcttttcttc agcaagtatt caagaatgaa
    25141 tcaatttcaa atgaattgtt agaacgctct ggattgtttg tcacgcatga tgatggccgt
    25201 atgtctgatc gtttttatca aagagtgatg tttccacttc gtaattctca aggccagacg
    25261 atcggttttt caggacgctg gcttgcacct gaaaaagggc aggaaaaaga tcagcccaaa
    25321 tacttgaata gtccagaaac agaactgttc aataaaagac aagttttatt taatcttgat
    25381 aaagcaagaa gcgatatccg gaaaaacgga gaaattttgt tgttcgaagg gtttatggat
    25441 gtgattgctg catggcaggc tggtatcaaa actggattag cttctatggg gacaagtcta
    25501 acagctcaac agatccaaca aatggaaaag ctgacgaaag aattggtctt ttgctatgac
    25561 ggagacaacg caggttttga agcaaccaat cgagggattg aattgcttcg gcaaaacagt
    25621 cgcttagcac tttctgtcgt agtcgttcca gaaaagcttg atcctgatga atatctccgt
    25681 aagtatggag aagcatcttt ccaagaatta gtggctcatg ggcgcgaaac agtctttact
    25741 tttaaatcac gttatttaaa acaagggaaa aatttagata atgaaaaaga caagatcgaa
    25801 tacctcgaag aattactagt tgaacttagc cgagttgttt caccaatcga acaagatatg
    25861 tatctatctc aactgtcaac agagtttcag atcggcagag agacgataca aaaacaactg
    25921 cgcgatcttc gaaggacaaa tcagcaaaat cgtcaagaac ctcaggaaag tcaacacact
    25981 caggttacga gacaagaaac tgcacggaaa aagagacctt tgacgcaagt agaaaaggca
    26041 gagcagattc tattatatcg tgcatttaaa gaagtttctg tccgtaatat tttaaaagaa
    26101 cgagaatttc agtttattca tgatgcatat gcagaagttt attttttatt cgatgcatat
    26161 gtctcacaac attatgaatt caaccttgca gagtttttag actttttgca agatgaaaat
    26221 ttaaggcggt tggtggtgga aatcgaatat ttaccggtgg cagaagaaag ttcgccacga
    26281 gaaatccaag acttgctaga tgtgatcagc aaatctggct tagctgatga aataacatta
    26341 aaaaaacaaa tgcagcaaga agccagacga actggaaaca aacagcttga gcttgaattg
    26401 acgattgaaa tcatcaattt aacgaaacag ttaaaacaag ccaaatagct actcaagggg
    26461 ggccttcttt tatggcaaat ggaacagata aaaaaacgta tgaagcagca gtagcagctt
    26521 tcatcaaaga aaacaaaccc aaacgacaag ttgtatatga tgatttatcc aatcagcttg
    26581 ctacaccatt cactttgaat gcagatgaaa tggacaaatt gatccaaaag attgaagacg
    26641 caggtatcag tgtggtggat gaaaatggtg atccatcaat tcacagcttg aagagtgctg
    26701 agaaaaaagc tgaacaagca aaaacagaag atctatctgc gccaaccggt gtaaaaatca
    26761 atgacccggt tcgtatgtat ctgaaagaaa ttggccgtgt ctccctttta actgcggaag
    26821 aagaagtagc gttagcattg aaaatcgaag aaggcgacca agaagcgaaa cagcgtctgg
    26881 cagaagcaaa ccttcgttta gtagtaagta tcgctaaacg ttatgtagga cgaggcatgc
    26941 agttccttga cttgatccaa gaaggaaaca tgggactgat gaaggcagtt gaaaaatttg
    27001 actaccgcaa aggatttaag ttttcaacct atgctacatg gtggattcgt caagccatca
    27061 ctcgagcaat cgctgaccaa gcacgtacga tccgtattcc agttcatatg gttgaaacaa
    27121 ttaataaatt gatacgtatc caacgtcaat tgctgcaaga ccttggaaga gaacctacgc
    27181 cagaagaaat cggtgcggaa atggatcttc caacagaaaa agtccgagaa atcttgaaaa
    27241 tcgcgcaaga acctgtttca cttgaaacgc caatcggtga agaagatgac tctcacttag
    27301 gtgatttcat agaagatcag gaagcaacaa gtccagcaga acacgcagct tatgagttac
    27361 taaaagaaca attggaagat gtactagata cattgactga ccgggaggaa aatgtccttc
    27421 gcttacgttt tggtttagat gatggccgga cgagaacatt ggaagaagta gggaaagtat
    27481 ttggtgttac tcgggaacgt attcgtcaga tcgaggctaa agcattaaga aaattgcgcc
    27541 atccttctcg ttcaaaacaa ttaaaagatt tcttagaata agcatgaact attgaccaga
    27601 agagaaatca gtaaaactgt ttggtttatt ttaaaagaaa aaaagcttga gactacgcag
    27661 tctcaagctt ttttttctat aggaaggaaa ttcattcatt atttttaagt aaatcctaaa
    27721 aataagctat tggcgtgacg tatagaatat gatagattaa atggtagcgt aaacctagta
    27781 aaggagccga tcgctaagtg atgaaaaaat gtccaaattg cggatcgaaa aaaatggagc
    27841 agaatactat ctgtccagac tgcggtcatc aaataactgc agaagatcag caaataaaag
    27901 aatcaattga agaaacaaat acagatgcag ctatgcagga taaatcaact gaagatgcag
    27961 tctttcctga tacagaatta aacgatccaa tcgaatggtc ggaattgaaa gatttacctc
    28021 tagaatctgt aatggaatta ttcgaaaaag cagaaccaga agacgaagaa ccacctgctc
    28081 acgatcaagt aactaatata gagaaaaatg aacagaagaa agcaactgtt catgagactt
    28141 cggaagaatc aggaaagaat caagaagaaa cgcttgaatc aaaacaaaaa agaagagtag
    28201 ctgaactgaa agaaatcgtc gataatgagg aagaaaattc gatactatcc gcttatatca
    28261 aagcacatcg tgaagataca aaagaagagc acgcgaaaga gctgctcaaa atgatcagtg
    28321 aaaaaattgc acaggaaaac aaagtagagc cagaacatga agctgaaaaa gacactgaaa
    28381 aagacattag tggagtaaac gctgcaggta aagaatcatt aaaaacgaat gatctaaaaa
    28441 cgaatgatct aaaaacggat atcccggaaa aaactgaaac attgtctgaa aaacaatcag
    28501 aagacgagaa atcgaatggg ttgccggaag cagataaaaa agaaatgctc gaaaaagcag
    28561 acaagaaggc aacagagtcg gatggaataa ataatgaagc cgatgctgaa actcaatctg
    28621 caagtgaaga tagcactgct cttgaagcta aaatagaaaa agaagagaac cagcctgagc
    28681 tgattgaagc agaaacagaa ccaataacaa tcgtgccaaa tactgaaaaa acgcctcaag
    28741 aatcaaaccc agaaaaaaaa gatttagata agacacaaaa gaaaaaatca aaaaaagtgc
    28801 cgtatctcgc tttagcagca gttcttctac taggtggggg aggctgggct tattatgacc
    28861 atcatcaaaa agtagaagcc gaagtagcag cagaagcaaa aagacagcaa caaatggaag
    28921 aacttcatga gaaacttgct gccttttata cagatgatca ccatcaattt attcgtgcag
    28981 atatgattca tcaagattta tcaaaactaa aaaatgattt atccagtctt aagaatgaaa
    29041 aaggatattc agagttagaa acaacttacc aagatatcca atctaagatc cgagatatcc
    29101 aaaaagtgaa tgagtggttc atagcacctg ccatcgtcga tgatcatcta gcagatgaca
    29161 tcaagttgaa agcagataaa gagatccaag caatcgaaac ggataacaca gattttggaa
    29221 aattgattca acaagcacaa acagaagcta aaaatcaata tgctgaattg caaacagcta
    29281 aagaaaaaac agctatagtc tttaaagacg gaaaagtagt ggattcagca acacgcgacc
    29341 aatacaagac ggcaaaagaa gcagtagaaa aagtgaaaaa tacagatcta tctgctcagt
    29401 tgaatgaaca attgcaacaa gtagataaga tgctcactga taaagagaaa aaagaagaag
    29461 aggaaaagaa aaaagcagaa gaagcgaaaa aagcagaaaa agcgaaaaaa gcagctgaag
    29521 aacaagcaaa acaagccgct caagcagcag ctgcagctca agccgctcaa caagctgcgg
    29581 tcgcacaagc agcacagcaa gaagcggcat cctcgacccc ttcctcttca aactcagcga
    29641 atcagccaat caaatctgcc agagcaagtg atattgccga tgcatctaat ccagcatgga
    29701 cgtgggcacc aggtgtccaa agcaaagtga ttgctacatg tatccaacgt ggatatatcg
    29761 ttgaaggagg atacagatta gaaaaagcca gaatcgaaaa tggggaaggc tattacaatc
    29821 tatatgccac ttcaacaaaa tctgcattga tgaaaggcat tggagaaagt gctttgccat
    29881 tttacatcgt aaccatcaac tgtaaaactg gatggttcgg aggaaatggg agcaattaat
    29941 tttaggcaaa tgaaagaggc tgtgagcctg ccgtttaaca ccgtttattc gaaaaagggg
    30001 agtatgacac aactgttgtc atactccttt tttcaccttt ccaaaccaag gctcagctat
    30061 tcaagtagat aacattatgt tatgatagca aagaaatgta ttaagaaaac ctttcactat
    30121 agagggagaa aaaaatgaac gatttattag caactatatt tacaggtatt attattgatg
    30181 aaaatgaaaa aaactacttt gtccaaaaaa acggacaaac ctttggctta agcaaatcag
    30241 aaggtgaaca caaaatcggt gaagcagtgg aaggattcgg ctaccaaaat caaaaacatg
    30301 aaaatcggat cactacacaa attcctaaaa gccgtatcgg tcattacgct tttggaatcg
    30361 ttactgctac acgaaaagat ttaggtgcgt ttgtcgatat cggtcttcca gataaagact
    30421 ttgtcgtatc tcttgatgaa ttgccgacaa tgacagagct atggcctaaa aaaggggatc
    30481 gcttgatgat ttcccttaga gttgatgcaa aagaccgtat ttggggcagt ttagcagatg
    30541 aaaaaatatt caaatcttta agcaaatatg gaacagaaga aatgaaaaac aaagatgtga
    30601 taggaacagc ataccgcttg aaattaacag gtacgtacgt tttaacggaa gatttctatc
    30661 ttgggtttat ccatccttct gaacgatata atgaacctcg tctaggcgag caaataaaag
    30721 gtcgagtgat tggtgtccga ccagacggtg tactgaatct ttcattgaag ccaagagcat
    30781 atgaagctat atcagatgat gcacaaatga ttttaaccat tttagaacgt tctgcagatc
    30841 agcaaatcaa ctttacagat aaatcggatc cagaagaaat catgaaagct tttggtatca
    30901 gcaaaggagc atttaagcgc gcattaggta atcttttgaa acaaggattg attacacaag
    30961 aaaacggtgt gacaaaacta gtcaaaaaat ctaattgaga atcccttgca tgtttttctt
    31021 aactagctta taataatttt aattaacata gtgttatatc tttttttatt tgtaattatt
    31081 ataaattgtt ggggttgagt aaatggtcat gaatgctatt tcggcgatga aaaaaacaaa
    31141 acagcagcta catgaagcgg ggtttaagct gacaccgcaa agagaagcta ctctgcttgt
    31201 gcttttggaa aatgagaaag agcatttatc tgcagaagaa atcttctttt tagtgaaaaa
    31261 aaagagtccg gaaattggac ttgctactgt ttatcgaacc cttgaaatct tgacagaatt
    31321 gaaaattgtc gataaagtaa gttttaatga tggattagcc cgttatgatt tgagaaaaga
    31381 aggcgccaaa catttccatc atcatttact atgcttgaac tgcggcacga tcgaggaagt
    31441 agaagaggat cttttacttg aagtggagca agtagtagaa gaacgttatc attttttagt
    31501 aaaagatcat cggctaacgt tccatggaat ctgtcaggaa tgctatgaaa aagaaaaaag
    31561 aaaccagtcc gtctgagtgt ctagacggct ttttctttgc tcagattatg gaaaaagact
    31621 atcagaatga agcggtatct gatatgatag agaggcatga gggggattat tatgaaagag
    31681 caaatcaacg attatctcca ctacttgaat attgaacggg gattgtccgc caatacacga
    31741 caaagctatg aacgtgattt ggaacagtac ttgcattttc tacaggagca gaaaattgct
    31801 tcatggcagg atgtcgatcg ctttttagtc atccgttttc tggagaagtt gcatgaagaa
    31861 aaaaaagcga cagcaactgt tactcggatg atctcaagtc tcagaagatt ccatcagttt
    31921 ttacggcaag agcgtatcac tgatcatgat ccgatgcaac atatcgatac gccgaagaaa
    31981 gcacagaaat taccaagtac attgactctg acagaagtag aaaagctgat tgaagcacct
    32041 gatacgacaa aaacgttagg gataagagat cgtgcaatct tggaagtcat gtatgctaca
    32101 gggatgcgcg tcagtgaatt gattggattg aaattgggag atcttcatct ttctcttgga
    32161 ctggtacaga cagttggaaa aggagataaa gagcggatca ttcctttagg tgattatgcg
    32221 atccaatggc tggaacgcta cttagacgaa gcacgtccat tacttgtaaa ggacgcatct
    32281 gaaatgcatg tatttgtcaa taatcatggg aaaggtcttt ctcggcaagg aatctggaaa
    32341 aatctgaagc agctagtacg agaggctggg atttacaaag aagtaacacc acatacgctg
    32401 cggcatagct ttgccacaca tctgctagaa aatggagctg atttgcggac agtacaggaa
    32461 ttgttaggtc acgcggatat ctctacgact cagatttata cacatatcac gaagaaaaga
    32521 atgacggatg tttataagca gcattttcca agggcttagt cataggaagg tgagaagatg
    32581 ttaacacatt accggaaaga aaaccgtaaa attgctatgg gactattgag tttccataag
    32641 aaactgacag gtaaaacttc tttgttgaag gagattgata cgtacgaatc tgaagacgat
    32701 tatgaacttt ttttctttac gccagaaggt tcaaccaaca ttcaagggat tattggtgtt
    32761 tactgggcaa cgaacgatca gctgatcatc catgacattt ctttgaatcc gtcttatcgc
    32821 ggtgagaata tgggctttca aatgttagat gaattacagg aaaagtaccc ggatgtctcc
    32881 atccgtgcaa ctgaaatcac agagccttac attggaaaat ggctagcaaa gaaaaagaag
    32941 aaagagtgaa tgagttgacg gagatcaata ttaaattaga tgtattcgaa ggtcctctcg
    33001 atctgctgct tcatctgatt cagcaaatgg aaatcgatat atatgatata ccgatcgcta
    33061 cgatcacgga gcaatatatg aattatatcc atacaatgaa aacactagag ctagctgttg
    33121 caggagaata cttagtgatg gctgctacat tgatggcaat caaaagcaag acattgcttc
    33181 ctgtccaaga attcgtcaca gatgatgaag aattatggga agaagatcct cgagaagaat
    33241 tggtcactca gcttttagaa taccgtaaat ataaatatgc agctgaaaga ctgacagaaa
    33301 aagcagagga acgaagtctt tattacacaa aagaacctat gaacatcgat gggttagcgg
    33361 atgctgaaaa gccgttgaag cgaggacaag tcaaaaaaat cgatttgatc cgtgccatgc
    33421 agaaaatctt agaacgtaag aaattttctc aaaaagtgga aaaaacgatc acgcccgatg
    33481 acacaacgat cgaagaacga atggtattta tcgaagagcg tataaaaaga aatgcgcatg
    33541 gctgtacttt cgattctttt tttgagtcac cttctaaaag tgaagttgtc actactttta
    33601 tggctttgct agaattgatg aaaaaagggc agatcattgc gcaacaaaaa gaaaactatg
    33661 aatcaattat gctttatcca gcagtaggag ataccgaaca tgacgaaatt aagtgaactt
    33721 gaagcccttc tttttattgt tggcgaggaa gggatcagta atgaagaatt aagcggactg
    33781 ttaaatctca gcgaagcaga agtcacaagt ttagtgaaag aattaaaaga atcttacact
    33841 caaaactcgc actcagcttt gcatattttt gaaacggaaa gccattatgt attaacgact
    33901 aaaaaagagc tggctccctt acttaagcga tatgcgcaag ggacatcaaa cacattatct
    33961 caagccgctg tcgaaacctt agcaatcatc gcttataaac agccaatcac aagagctgaa
    34021 atcgagcaga ttcgaggagt tcaggtttca ggagcggtac agcgtctagc tgcccataaa
    34081 ctgattgaag aaaaaggtag agtagaaggg ccaggtcggc cgatattata tggaacaact
    34141 ggctacttct tagattattt tggtttgaaa tcattagaag aactgcctga tacacaagaa
    34201 atggaaattt catttgaaga agacgtgtca ccagatctat tctttgatgg aatgaataaa
    34261 ggagaataat tgtaatggaa agattgcaga aagtaattgc ccacgctggc atcacttctc
    34321 gtcgaaaagc agaagaattc atccttgcag gacgtgtaaa agtaaacgga caagttgtaa
    34381 gggaattagg gataaaagtt gggaaacatg acactgtgga agtggatgaa gtcccaattt
    34441 atcaagaaga atacggttat tatttattgt acaaacctaa aggagttatt tctgctgttg
    34501 cagatgacaa aggaagaaaa gttgttacgg atcttttgcc gatggtaaaa gaacgtatct
    34561 atcctgtagg tcgactggat tacgatactt cggggatctt gctactgaca aatgatggag
    34621 attttgctca gcgcctgaca catccaaaac atgaagtgga taaagtttac gttgcaaagg
    34681 taaaagggat cgctacaaaa tcgatgcttg cacctttgac aaaaggaata aagatcgaag
    34741 gacgaaaaac atctccagct aaattccaaa ttttatcagt ggatcctaag acaaaccaca
    34801 gtatcgtgga attgacgatc cacgaaggac gtaatcatca agtgaaaaat atgcttcaag
    34861 cagttggtct tcctgtgcaa aaactaaaac gtgaaaaata cggagatctg actttacaag
    34921 gcctacgtcc tggagattac cgtgaactga acaaaaaaga agtcagcagt ttgctgaacc
    34981 actcaaaatg aacacttact ttttataagt gttagatgtt gcgttttttg aatagatatg
    35041 tataatgaat atgtaaacaa aaattatata aggttcgtct tcaggggcag ggtgaaattc
    35101 ccgaccggtg gttatagtcc acgacctatt ttgcaaaaaa tagctgaatc ggtgaaattc
    35161 cgataccgac agtatagtct ggataaagaa gatagagctt atttgacgac gcttgatcaa
    35221 ataactctaa ctctattttc cctggaaaat agagtttttt catttggaga gaaacgtcaa
    35281 aaagttcgct gaagaggagt cctaacagga ggatttcaaa tgaagaacac ccgtgtacag
    35341 aaaatggttg cagtagcgat gtttgctgcg atcgcgttag ttttacagta ttttgctttt
    35401 ccgatcatgc cggcttttag ttttttgaag atcgatttta gtgatatccc ggtattgatc
    35461 agcatgttct tattcggtcc agcggccgga gttgcaacag cgttcttgcg ttcagtatta
    35521 catctgctga ctacaggttt ttctccggat aatttggtag gagacactgc tagtttctta
    35581 tcaacaacga tctttacatt cccgatttat tatttcttta gtgtaaagaa acagcataaa
    35641 ggaagaaaca aatttttagg tgtcattaca ggaaccatcg ctctaactat ttttatgagt
    35701 atcgcaaatt atttcgttat tacgcctctt tacttaatgt ttttaggact gaacgcaaca
    35761 cagatgctag gcatgtcttt agcaaactat gtactgattg ggatcgttcc tttcaacttg
    35821 atcaaaggat tcatcgtgag cgctgtcttt ttagtgctgc atgcgcaact tcttccatgg
    35881 ttaagtcgaa aacaacatca gttcgaacaa cgtcatacag cagtcaaata attatcaaaa
    35941 agatcaagaa atttcttggt cttttttttt ggaaaaaaat acaagacatg caataatgta
    36001 aacgttttat ttgtttgttt tgagtatttt tttgatttat gcataaaaat caatcaattc
    36061 tttgcaaatg tgaaattctt ctccttttaa aagacgaaaa tgtttgttta taaaaaaaag
    36121 gaaacgctac aatgaaaaag aagaaagctt taaaaacctg aaaaaagagg agggaatagg
    36181 gaaaaacgaa ctttttgaac aaaagtttta caaaatgcgt gttattattt ttgttctgat
    36241 actctttttg ataaaataac attagagcca aaattgttgt ctctaacgga aaagaaagga
    36301 agaagaagat ggaacaaaca aaaaagaaaa aatttcaaat gccttcagcg tatacggtct
    36361 tatttattat tattgcagta atcgctgtac ttacttggtt tataccagct gggcactata
    36421 gtgtagacga tgcaggcaac atcgtcgctg gatcatatga acgagtacaa caaaatcctc
    36481 aagggctgtg ggatattttc atggcgccaa tcaatgggat gttaggtgta ccagcggggg
    36541 agctaactaa agaaacacct gctgcaatcc caatctcttt cttcattttg gttgttggtg
    36601 gatttttagg tattatcaac aaaacagggg cactagatgc cgggattgct tcagttgtga
    36661 agaaattcaa aggaaaagaa aaaatgctta ttccagtatt gatgctgtta tttgcattag
    36721 gcggctctac ttacggaatg gcagaagaaa cgattccatt ctatgcttta ctgatcccag
    36781 ttatgatggc tgtaggcttt gatacagtag tagcagtagc aatcgtatta gtagggtctc
    36841 aagtaggctg tctagcttca acggtaaatc cttttgcaac aggcgtagct tcacaagctg
    36901 ttgggatttc gatgggtgaa ggtattggtc ttcgattctt gatgttcgtt attttgttag
    36961 ctatttctat tgtatatgtg tatcgttatg catcaaagat cgaaaaagat ccaacaaaat
    37021 cattagtata caaccaacgt aaagaagata tgaagcattt cgatattgaa gcaatcggtc
    37081 gtcaagaagt aatcacgaaa aaacaaaaac atgttaatgt attgttcttt attacttttg
    37141 gtatcatgat catcagtttg attccttgga caaccttgaa tgcgaatttc acgatttttg
    37201 aatcattgac aaactggtta acaaaccttc cggtactagg tactgttcta ggtaaaagca
    37261 tgcttccatt aggtgactgg tacttcccag aaattactat gttattctta gtaatgtcca
    37321 tcgtagtagc aatcacttat ggcatgaaag agtctgaatt tgtctctgaa tttttagctg
    37381 gtgcttctga tttgatcggt gtagcaatcg tagtagctgt tgctcgtggt atccaagtgg
    37441 ttatgaacaa tggattaatc acagacacca tcttacattg gggcgaacaa ggattaagtt
    37501 cattatcttc aagtgtattc atcattatta catttatttt ctatatccct atgtcattct
    37561 tgattccttc aacttccggc ttagctgctg caacaatggg aatcatggga cctatgggtg
    37621 aatttgccgg cgtcggtaag gatttagtaa tcactgctta tcaatctgca tctggtttag
    37681 taaacttaat tacaccaaca tctgctatcg taatgggtgc tgtagcaatt gctcgtttcg
    37741 atgtttcagt gtggtggaaa tttaccggta aattaattgc gatattattt gtagccatct
    37801 gtgtgatcct aggtgtagca gcaatgttct aaacctagac aaatacaggt acaaggtcta
    37861 tcataagaat gaagaaaccg ataaacggct atcgataagc acgtggacaa gtcaatagct
    37921 ccattcagtg agtgtttttt ctttcatcat ttgttaagaa cattctgctt gctgatggag
    37981 caggcttaaa acgtcattat ttgagaagaa gaggttgtgt cggaggaatt tgacatgacc
    38041 ctttttaaca tattaggagg ataatatcat gaaaaaattt gtgacagaac aacatcatga
    38101 acaagcatta gaatcattga gcgaattgat ccgaattcct tccgtactag atgaagcaga
    38161 ttcaggacaa ggacatccct tcggtaaaaa agtgattgaa gctttggata aagtattgga
    38221 aatcagtgaa aagctaggat ttagaacatt taaagatcca gaaggctatt acggttattc
    38281 agagattggc tctggagatg aattattcgg tatcttgtgt catatggacg ttgttccagc
    38341 aggggacgaa aataattggg aaacaaaacc attcgatcca actataaaag acggctggtt
    38401 agttggtcgc ggatcccaag atgacaaagg tccttctatt gcggcaatgt atgccgtcaa
    38461 agctttgatt gatgctggcg tggaattcaa gacacgtatt cgttttatct ttggtacaga
    38521 tgaagaaaat ttatggcgtt gtttagaaaa atataacgaa aaagaagaag gaattacgca
    38581 aggatttgcg ccagatgctg aatttccttt aatttatgca gaaaaaggct tattgcaagc
    38641 ttacttgaca ggaccaggaa cgaacgagtt ttctgtaaaa gctggaggag cgttgaatgt
    38701 tgttcctgat gcagctcctt actctggaga aaagctttct gaagtaaaag aagcgttgaa
    38761 aaaacacgaa ttcgatttcg aagaacaagg tgaaggcatc gtcgttcttg gtaaaagtat
    38821 ccacgcgaaa gatgcagcac aaggagtgaa tgctatttct cgtctggcaa ttgctctttc
    38881 agaagtattc gattttggcc caatcaattt cttaggaaaa ttagttcaag aaaatgcaac
    38941 tggtgaagct gtcgtgggca aaacagaaga tgaacaatcc ggcgagctaa cgatgaactt
    39001 tgcaagtttg gaaatcacac cagaacaaac aaaaatcggt gtagatatga gaatccctgt
    39061 tacattcaag aaagatgatt tagtagctaa attaactaaa acagcagaaa aatatgggtt
    39121 gacttatgaa gaatttgact tccttgattc attatacgtg ccactagaca gtgagttagt
    39181 gaaaaatcta ttggggacat atcgcgatat tactggagac atgactgaac cgtttgtatc
    39241 aggcggcgct acttttgctc gtacgatgaa ccagtgtgtg gcattcggtg cgatgttccc
    39301 tgatactcct gactttatgc accaggcgaa tgaacgatgg gaattaagta gtatgtataa
    39361 agcaatggaa atttatgcag aagctgtgta tcgtttatgt gctaaataaa aataaacata
    39421 caaaaagggc ggatattcaa atggatattc cgtctttttt tatttgatgc tggaaagttt
    39481 gcatttctct cttatttttt ttaaggtata atcatacttg attaagaaaa aggggtcact
    39541 cagatagaaa aggtgggaga aagtgaaaat atttagacga atactaattg gcttagtcat
    39601 cattttagga ttactcggtg gagccggtta ttactatata cagcaaaata cgtacgaacc
    39661 atcgtcagaa gcgcaagtgt tggtaaaaga aggaaaaaac aaagaagatt acttattttt
    39721 tgaaggagag aaaaagaatc atggaaattc tccattactt attttttatc ctggtgctct
    39781 cgtagagcca gaaagttata gtatttgggc gcaagattta gcaaaaaacg gcttttcagt
    39841 cgctattgtc aaaatgccac ttgatctagc agtgatgggc ggaaacaaag cggataaggt
    39901 caaagaagat tttccaaatt ccgattatgt gatcggtggc cattcattag gtggcgtaat
    39961 ggcaagtcgt tatgtcaata agaatcattc agacaaacat ttaaaagggg tattcttcat
    40021 ggcaagttat cccgacaaaa aaggaacatt gacagaatca gctgttcctg ttttatcgat
    40081 cacggcgaca aaagataaag tattgaatca ggaagcttat caagaagcta agcagtattt
    40141 accggaaaga acagagtatg tatcaatcaa tggcggaaat catggaggtt ttggcagcta
    40201 tggtgagcaa aaaggagatg gagaggcaga aatttctaac gcagaccagc aaactgtgat
    40261 cgtcaataca ttggaaaact ggctgaaaaa gttgaaataa tataaatggg tcctataggg
    40321 tccgtgaaaa aactagtcaa ttaactatag atagcaaatg aatctttcaa aataagtcgg
    40381 gatttcacgg aacaagagaa acagatcccg gcttattttc aagtttagag aacttagtgt
    40441 acgtttttaa agtttcgttt atatttatat tttattttct aataaaatcg ctcgaactgg
    40501 acatttttga tacgcttttt ttacatatgt ttcttcttcc ggcatcacga actgttgatg
    40561 agcctctggt tcttgggcaa ataaaacgat tccttcttca tcataatcga aaatatctgg
    40621 cgcttcgatt tgacaaagac cgcatgcaat acagcgttca ggtacaagtt tacatagtag
    40681 tgacatttct aaccatccta acttaaggag aataatatga ttgtttttat tttatcgcta
    40741 ttttcatcag gacacaagct gcggattagt tctctttacc aactccttgt gggaaaacga
    40801 acgacttcag tacttattta tggatttacc cacgaacttt tgtttatcca taacagtttt
    40861 ccagaattga agcaggataa gttttatcaa attttgcaaa aaattgcgca gcaaggttgg
    40921 atcgaaataa atgaaaatga agcaaagcta acgcctgcag gggctgatat gttgtccgaa
    40981 catcaaatag aacatactgg tttgcgtttt gaccgctatg gcagaacagg ggaaactagt
    41041 tggcggctca ttaaatttgc tgttcaagta atttctaatc tggcaacggg tattcaagac
    41101 tatcttccag cagagacaag tcctttttat actttccaac taaaaaaatg gcttagtgaa
    41161 agccaattgc cacgtgaaat tttgattgat actgcgtatg agagtttggt gcagctgttt
    41221 tcggagatac cagaagaagc agcagatttt ttagctaacc aattatctgg aaatgagcga
    41281 acagggctgc ttccttatca gctggcaaaa aacaatgatg agtcagcggt ttatctgcaa
    41341 caaagcagat gtatccacct tttgttagca caaatcgaaa aacggccaga ttcgctttgg
    41401 cacgctttga tcgattcatt attacagcaa aatttcaatc aaagcatgat gatcaccaag
    41461 cagatgttta tgaatggtca gacaattgac cagattatgg caatccgtca tttaaaaaga
    41521 ggaacagtaa cagatcatct tattgagtgg gccttgtttt ttgatgattt tccatacgag
    41581 cggattctct ctgcagaaac aatcgaacgt ttggaaccaa ataaggattc cgtgcgagag
    41641 tggcgcttta gcgaatggaa tgtagatgga caattagatt atggagaatt tcgtttgtat
    41701 caaatctatc tattgagaaa ggaagcgata cagaatgtta ataaatgaat taaaaaaata
    41761 ttttggattt gattcatttc gtcccggcca agaagaaatc attcaggcgt tgcttgatgg
    41821 agaagatact ctcgctattt tgcctacagg aacgggaaaa agcctttgct atcaattgac
    41881 ggggttttta atggaaggtc tggtcatcat cgtgtcaccg ctgctttctc taatggaaga
    41941 tcaagtgacg caattacaaa aacgagggga gaaacgagta gctgctttca atagtttact
    42001 ttcgcaatct gaaagaagat acgtcctccg tcatctatcg caatataaat ttttgttttt
    42061 gagtcccgaa atgttgacta atccttctct tttagagcat ctgaaaaaac aaaatattgc
    42121 gttatatgta gtagatgagg ctcattgcgt gtctcaatgg ggagttgatt tccgtccaga
    42181 atatcaacag ttaggaaaaa tccgaaagct tttaggaaac ccggtcacac tggcactaac
    42241 ggcgacagca acagatttag tagcaagaga tatacgtcat gtactatttg atcgaccacc
    42301 aaaagagatc agacaatcag tcaatcggca aaatatctcg ctttttgttc ggaaaacgca
    42361 gcaaaaagaa caagaacttg aacacttcat ggaaagagca caaggagcgg caatcattta
    42421 ttgtgcaaca aaaaaagaag tcgaacgatt gtatcattta ttcagggaac gttttacagt
    42481 tggatactat cacggtggtc ttgatgcagc tcaaagaaga caacttcaac agcagtttgt
    42541 aaaaaatcag ctgcagtttc tcattgctac gaatgcattt ggtatgggga tcgataaatc
    42601 tgatatccgt tatgtgatcc attatgattt gccagacagt ctagaaaact atgtacaaga
    42661 aatcggtcga gcaggcagag atcaggaaga aagtgcagca attctttttt atcaaagtgg
    42721 ggatgaacgt atccattatt tctttaatca actttctaga gaacagcgac aaagttttga
    42781 gctttatttg gaatatgcca cagagcaagc tccctttgat gagctgcaaa aaaaatggat
    42841 ggagctgatc cagcagtctg aaaaaccaga aaattgggtg gaacggctca aacatcagga
    42901 aaaagaaaaa gaattccgcc tgcagcagat gcttcgctat attaatgaag aaaactgccg
    42961 cagaaaattc atcttagctt attttggcga aaaactctcc gaaaagccgc agaattgttg
    43021 tgatattgat ggagcaaaag cagaacttct gccaaagagg aagctttttt ctaagactga
    43081 acaacttcat tgggaaacga ttttactaaa tttatttaaa aaaaacatgg aacattgatt
    43141 ttttaggaca agacactttt tcctatggta taatacacac gatagagttt aggaggtaaa
    43201 acagtgagca gaaaagatag acatcaatct acagaaaata acgaaacaca agaaccatgg
    43261 gaacaaccaa tctacgatac agatgatgaa gtttcatcaa gaagttctca gagacaacaa
    43321 aagaaaggaa atacattatt tctttcgcta tttttgattt tactggtctt atgtatcgct
    43381 attccagcag gtgcttattt ctggatcaga aatggatcaa gcaacaatgc aacagcagca
    43441 acttcttctg aaacttcgac atcagtagta gaaagttcta caagtacaac aaaagaggag
    43501 tcaactgaga cttcaacagt agaatctagt acaatcgcgg aagaatctac tgtgtctcaa
    43561 gatacaggtg taacgtcaga aagcagtatt gcagcagaga caacaccgac ttcctcaagt
    43621 gaggcaactt atcaagcagg ggattcaagc agcaatgcag cagaaacaac accttcttca
    43681 tcagctgcag ccggttcaac aacgactgtt caagcaggcg aaggtccaaa acaagtggct
    43741 gagcgtgcag ggatcaccac tgatcaattg tttgaattga atggcttaga tccaaacaac
    43801 tttatgcttt accctggtca agaattaaga attaaataat aatagccgcg ctttgcggct
    43861 ttttttttga gaaaaaggag ttatatcatg acacaaatca gtattgcaat cgacgggcct
    43921 gcttcatctg ggaaaagtac cgttgccaag atattagcaa aagaattgaa ttatatttat
    43981 acagataccg gtgccatgta tcgcgcagta acttatttag ctattacgaa caatgtatcc
    44041 ttttcagatg aagaagggct agtttcgctg atcaaaaagt atcctatctc tttttcgcaa
    44101 caagaagatg gacagcatgt attcatagca tcaaaagatg tgactttaga aatccgtcaa
    44161 ccagatgtca caaaagctgt ttctgaagtc tctgcacatg gaaaagtcag agaagaatta
    44221 gttgctatcc aacgaaaaat aggggaacgc ggtggcgttg tcatggacgg aagagacatc
    44281 gggacagctg tattaccgaa tgcagaagtg aaaatctttt tagtagcaag cgtaagtgag
    44341 cgtgcagaaa gacgtttcaa agagaaccaa gaaaaaggaa ttccgactga tcttgaaaca
    44401 ctgacgaaag agatacagga aagagaccat tatgattcaa caagggacgt ctctccgctg
    44461 aagcaagcag aggatgctgt tcgtatcgat acgactggca aatcgattcc agaagtcgtt
    44521 gcagcaataa aagctgttgt tttgaaaaaa ggttatcttc ttttttaaat taagaaaaaa
    44581 aatgaaaaac aattgttttt tcaaggaaaa cgaacgaaat cgctttattt tttttgaata
    44641 atcaattaaa ctaaaaacag taccgtactt acggcagaat gttggttagg aggacaagtg
    44701 ttatgacaga atttgatcaa aatcaagaga acaaccagtc aatggaagac gcaatgaaaa
    44761 gcgtacaaga agtaaaagtt ggcgatgttg ttaagggcga agttttagtc attgaagaca
    44821 aacaagtgat tgtcggaatc gaaggggctg gagttgaagg agtcgttccg gcaaaagaat
    44881 tatcaacttt gccggtagaa gatatcagcg aagtagtaaa agtcggtgat gtattagact
    44941 tagtcgttat cagtacgatc ggcaaagata aagaaaacgg cagctaccta ctttcaaaac
    45001 gccgtttaga tgctaaaaaa gtttgggaag atatcgaaag agatttccaa gagggcaagg
    45061 tgatcgaagc acctgttaca aatgttgtca aaggcggttt agtcgttgac gtcggtgtac
    45121 gtggttttgt ccctgcatca atggtggaag atcattttgt tgcagacttt tcagactata
    45181 aaggcaaaac attgagcttt aaaatcatcg aaatcgaacc atcagaaaat cgtttgatct
    45241 tatcgcataa agcggtagtg gaaaacgaaa gagaagaaaa gaaaaaagaa attctttcaa
    45301 ctatccatga gggagatgtt ctcagtggac gtgttgcacg tcttactgat tttggcgcat
    45361 ttgtcgacct aggcggaatt gacggtctag tccatgtctc agagatttca catagtcatg
    45421 tagcaaaacc aagtgatgta ttggctgtca atgatgatgt aaatgtcaaa gtgttgtcta
    45481 tcaatcctga acaagaacgt gtttccttgt ccatcaaaga cacacagcct ggaccttggt
    45541 cagaaatcga tacaaaagct ccagttggca cagtattaga cggaacagtt aaacgtttga
    45601 caagcttcgg tgcctttgtt gaagtgttcc ctggagtaga agggctagtc catatctctc
    45661 aaatttcaca taaacatatt gcgacaccac atgaagtgct tcatgaaggt gacgaagtga
    45721 aagtgaaagt attagagatc catccagaag aacatcgtat tgcattgagt atcaaagctt
    45781 tagaagaaaa accagcttca gaagaagaac caaaaaatgt tgagtcttat gaattaccag
    45841 aagaaaatac tggatttact atgggagaca ttttaggtga tgcgttgaaa gaagaagtag
    45901 aagaaaaagc aaccgatgat tctgaaaaat aattgatttt gtatctgtga ctgagatgaa
    45961 agcagctgct tttgtctcag tttttctttt gaaaagcgat tagtatttca ataaggaata
    46021 aaaatacttc gtttaattga caatctatgc ttgaaagttg gcaatgcatt cgttaaacta
    46081 agtgagattg gaaacttgtg aggaggaaat aatatggcaa atccaacaat tgcaatcgtt
    46141 ggccgcccga acgtcggtaa gtctacgatt tttaaccgca tcgctggtga gcgtatctcg
    46201 attgtcgaag atactcctgg agtaactcgt gatcgtattt atgcaaaagg tgaatggtta
    46261 ggtcgagaat tcagcgtgat cgacacaggc ggaattgatc ttggcgatga accctttatg
    46321 gatcagatca agcatcaagc agaaatcgcg attgaagaag cagatgtaat catttgtgta
    46381 gtcagcggac gcgaaggcgt gacagacgca gatgagatgg ttgcgaaaat tttatacaga
    46441 agtaataaac cagtgatttt agcagtcaat aaagtagata atccagaaat gagaaacgat
    46501 atctatgaat tttattcctt agggctaggc gatccttatc ctgtttcagg aagccatgga
    46561 ctagggattg gtgatatttt agatgaagca gtgaagtatt tctctgaaga gactgaagaa
    46621 gaggacgacg acacgattaa gtttagtttg attggtcgcc caaatgttgg taaatcctct
    46681 ttgatcaatg cgattttagg agaagaacgt gtaattgttt cggatattga aggaacgacc
    46741 cgagacgcaa tcgacaccca cttcgtttct gaaagtggtc agaaattctt aatgatcgat
    46801 acagctggta tgcgtaaacg cggaaaagta tacgaaaata ctgaaaaata cagcgtgatg
    46861 cgtgcaatgc gtgccattga ccgttctgat atcgttttga tggtactgaa tgctgaagaa
    46921 gggattcggg aacaagacaa gcgagtagcg ggttacgccc atgaagctgg tcgtggaatt
    46981 attatcgtcg tgaataaatg ggatcttgta aagaaagaaa ccaatacaat gcgtgatttc
    47041 gaacaagaga ttcgtgatga attccggtat cttgattacg ctccaatcgt ttttgtttct
    47101 gcagtgacta aacaacggtt ggaacgtctg cctgaaatga tcgaacaagt aagtatgaac
    47161 cagaatcttc gtatctcttc ggctgtgttg aatgatatca ttatggatgc tgtagcaatc
    47221 aatccaacac caacagataa aggaaaacgc ctgaagattt tttatgctac acaagtcgct
    47281 gtcaaaccac ctacatttgt cgtttttgtc aatgaagagg aattgatgca tttttcttat
    47341 gaacgtttct tagaaaatca aatcagaaaa gcatttactt ttgaagggac gtccatccga
    47401 attatccctc gtaggagaaa ataggcattt taccatatcg acgttttttt ttcaaaagaa
    47461 aaagacagtt tcgtttgtta cgtttctatg actaaaaaaa gcatgtgaaa attggtaaaa
    47521 accttgctat taagcggttc atatgatatc gtgataacag aatattgaag ttaatcaata
    47581 tttcttttta aacttctgga ccactcagaa agttttaact aaatgatatt tctatcatat
    47641 ctcttgtgga ggaggtgaat ctatccatgg caaacaaagc agaattaatc gaaaaagttg
    47701 cttcagctac tgatttaact aaaaaagatg caactgcagc agtagatgct gtattttcaa
    47761 ctattcaaga tgctttagct aacggcgaaa aagttcaatt aatcggtttt ggtaactttg
    47821 aagttcgcga acgcgcagct cgcaaaggtc gcaacccaca aactggtgaa gaaatcgaaa
    47881 ttccagctag caaagtacct gcattcaaac caggtaaagc attaaaagac gctgttaaat
    47941 aagacagttg aaaaagcgct tgtggctcta gggctacaag tgcttttctt tttatttcct
    48001 agcagaaaag gaataaataa gagacagaga ttccgaatcc gtatgtcata catagaaaac
    48061 acatgtattt tatttaattt ttatttattt ccaagttatg aggtgagctt tgctcttatc
    48121 ttttctagaa tttgcttact aatggtaaaa taaaaataag aagaggaggg atgcgtatgg
    48181 aacttgatta tcaagtagaa gatgcgttga cgaaagtgtt ttacggagaa acgctagtca
    48241 gccagctaag agaactttcc attgatcagc caatcttatt tttaacgaat cagcgctatt
    48301 atgatttgtt tgcagataag atcaacccgt tatttgcaaa tcaagcaaac aatgactggt
    48361 atatttgtgc caacactcaa tgcaatcatt taacagaatt aaagaacctg cttgatttcg
    48421 tcaaacgcta tcccgaaaat caatccatgt ttatcatcgg atttggaaat gaagggatca
    48481 tggatctggc aggttttttt caaaaacata caacccttga ttcatcacta tggatgatcc
    48541 ctgtatcgat ccgttctcta agccgagcat taacaccgca gcggacgatt ttgcagctac
    48601 caaatcgtgt agtactgcaa accatcaatc tgccagaacg catcgtttat gatcaaacaa
    48661 tcagcgagcg gcaagtggac ggaaagcaga ttgacttttt gacttttatc tgttgcggaa
    48721 tgatttgtga tcatcgtttt ttgcaaaatc tgtataaaaa ctatccaaat aaaaagcaat
    48781 taacgactcg gccgtttgcc gggatgatcg aagaaatgat ctatttttat caattagagg
    48841 cagaaaacct gtcaaattat ggtaaactgt ttgaacaagc tttttatctg accgaaaatg
    48901 gccatctact ttctgctagt atgaaaaaat ttttaggaat gatgtttcat ttcgtgtgga
    48961 atctccaagc atatcctttt gatttccaac taaaaaactt ttttgtgtgg ctggacttgc
    49021 ttggctatcc aatccactgg ctggaacaga tttcaaagat ggagtatttg gaaaaagttc
    49081 tttttttggc agaaaaaagc aaaaaaatac ttgttttaga aaaaataggt ataatagacg
    49141 gataccaacg tccaaacgaa aaagaattat tgagaacaat gacggtattt caacaaatcg
    49201 tcagtgagat aagagggaat tgaaatgaat acaaatagcg aaaaaatgtt gcaagcttta
    49261 tcagatgaag acttgtcaca agcacaaatc tttttagaaa aagcattaaa agaagaccca
    49321 gcagatatat tagctgaact aggcgaagaa ttgctggcta ttggcttttt gatcgaagca
    49381 aaacagattt ttgaacaact gatcaaccaa tacccagaaa atgacggact gaacatcccg
    49441 ttagcagaaa ttgcaatcga agataatgag atcgacttag cttttgaata cctggaaaaa
    49501 gtggataagc aaagtgatta ctatccgcaa agcttattgg cgatagctga tttgtaccaa
    49561 gttatcggaa tccctgaagt gagtgaagca aaattgaaag aagcagctgg gttgcttcct
    49621 gatgaaccat tgatccagtt tgcgctagct gaattgtatt tttcagttga tcgtttcaaa
    49681 gaggcagcag tggtttatga aacattgttg gcaagcggga taaatgaaat ttcaggaatc
    49741 tcgatgcagg aacgtttagg acaatcctta agtatgcaag gagaattcga agcagctatc
    49801 gcacctttag aagaagcact gaaagaagaa aggacagatg atcgactgtt ccagctagct
    49861 tttacgaatc ttcaattgaa agaaaatcag caggcaatca actatctgga agaacttcga
    49921 gaagttaatc cgcattatca atcgttatat ctatatctag gacaagctct tcaagaagaa
    49981 gaaatgattg aagaagcaca aacagtgtta gaagaaggaa tcaaagaaaa tccttaccaa
    50041 gtcgaacttt atcacctggc ctcggaaaat gctttccgtc tgcatgatag acagcgagca
    50101 gaagaacttt tactgaaagc tttagaagta ggagacaaac aagatgaaac attacttact
    50161 ttaagcaatc tttacttgga tgatgaaaga tatgaagatg tgatacaagt gatcaatcag
    50221 atggaagaaa ctgctaatcc ttatgcagaa tggaacctag cccatgctta taatgaatta
    50281 gaagacttta ccgttgcagc tgtacactat gaacaggctt atcatgaact atcacatgaa
    50341 ccagatttct tgaaagagta tgcctttttc ttaagagaag aagggcagct gaaaagagcg
    50401 caagaattat tgacttatta tttaacactt gaaccaggag atatggaggc actgtcatta
    50461 ttagatgacc taacagagag gtgagaaaaa tgctaattga tgtacgggaa aagaagaatt
    50521 ttttaacgtg gatggtcaat catgtatctt ttagccgaag agaagttttt tggatcttga
    50581 attatcttgc caatcatgaa gcgattttaa gcaatgtcca ctttgttgaa ggggcgaatt
    50641 ttgcggatcg aggactgcag atcagtgatc tatctgttga aggggaaccc atgaaattgt
    50701 ttttgcaggg aaaagaattt acggacacag accagatttt tcatgaaatc cgtttgaatt
    50761 ggaaaaagcc tttatatgtg gaatgtatat tcgaaaatgc ttggcagaca agagaatatc
    50821 tatctatctt agaagacaat ccattttctt cttgggattc ttcagtcagt gaagaagata
    50881 ctgaattaat tgaacgatat tttcaagaaa aagaagaaga ggcaaaacta aaaatgcttt
    50941 atgctcaaat cgatcaagca ctagaagatg gagataggga tgcttttttg aaattatctg
    51001 atgaagttaa ccgaaagatc cttttgcaga cacaaaagaa aagtaaccgg gtaagtgaac
    51061 ataacaatta gttaaaaata gtatagtact aaaaaagaca aagatcagct ggatgtggaa
    51121 tc
//
LOCUS       DAPBCF010000017        48705 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.017, whole genome shotgun sequence.
ACCESSION   DAPBCF010000017 DAPBCF010000000
VERSION     DAPBCF010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 48705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.017"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            23..646
                     /locus_tag="RD508_001210"
     CDS             23..646
                     /locus_tag="RD508_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735821.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="RD508_001211"
     CDS             1096..2145
                     /locus_tag="RD508_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7735822.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="RD508_001212"
     CDS             2142..3023
                     /locus_tag="RD508_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7735823.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="RD508_001213"
     CDS             3026..3796
                     /locus_tag="RD508_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7735824.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="RD508_001214"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="RD508_001214"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDT7735825.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="RD508_001215"
     CDS             5107..6270
                     /locus_tag="RD508_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7735826.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="RD508_001216"
     CDS             6387..6797
                     /locus_tag="RD508_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7735827.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="RD508_001217"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="RD508_001217"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDT7735828.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="RD508_001218"
     CDS             9370..9654
                     /locus_tag="RD508_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735829.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="RD508_001219"
     CDS             9814..10050
                     /locus_tag="RD508_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7735830.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="RD508_001220"
     CDS             10047..10445
                     /locus_tag="RD508_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HDT7735831.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11112..12056)
                     /locus_tag="RD508_001221"
     CDS             complement(11112..12056)
                     /locus_tag="RD508_001221"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDT7735832.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12352..13296)
                     /locus_tag="RD508_001222"
     CDS             complement(12352..13296)
                     /locus_tag="RD508_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7735833.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13517..14731
                     /locus_tag="RD508_001223"
     CDS             13517..14731
                     /locus_tag="RD508_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7735834.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASIYGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14753..16768
                     /locus_tag="RD508_001224"
     CDS             14753..16768
                     /locus_tag="RD508_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase"
                     /protein_id="HDT7735835.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEETFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16851..18224)
                     /locus_tag="RD508_001225"
     CDS             complement(16851..18224)
                     /locus_tag="RD508_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDT7735836.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18250..18534)
                     /locus_tag="RD508_001226"
     CDS             complement(18250..18534)
                     /locus_tag="RD508_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7735837.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18536..20551)
                     /locus_tag="RD508_001227"
     CDS             complement(18536..20551)
                     /locus_tag="RD508_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7735838.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20730..21035)
                     /locus_tag="RD508_001228"
     CDS             complement(20730..21035)
                     /locus_tag="RD508_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HDT7735839.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21124..22155)
                     /locus_tag="RD508_001229"
     CDS             complement(21124..22155)
                     /locus_tag="RD508_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7735840.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22362..23237
                     /locus_tag="RD508_001230"
     CDS             22362..23237
                     /locus_tag="RD508_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7735841.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23389..24231)
                     /locus_tag="RD508_001231"
     CDS             complement(23389..24231)
                     /locus_tag="RD508_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7735842.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24323..26200)
                     /locus_tag="RD508_001232"
     CDS             complement(24323..26200)
                     /locus_tag="RD508_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HDT7735843.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     RPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEATIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIDNQTNTPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDHETSGTYAYVLYDG
                     DKEIDPTNYSVTEQTNGFTVSVDSNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26197..27618)
                     /locus_tag="RD508_001233"
     CDS             complement(26197..27618)
                     /locus_tag="RD508_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HDT7735844.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQAATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQTEIAKNGA
                     SSGTFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKAPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGISTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27621..31010)
                     /locus_tag="RD508_001234"
     CDS             complement(27621..31010)
                     /locus_tag="RD508_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDT7735845.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDCVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNSWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKNLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31267..32658
                     /locus_tag="RD508_001235"
     CDS             31267..32658
                     /locus_tag="RD508_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7735846.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32731..33378)
                     /locus_tag="RD508_001236"
     CDS             complement(32731..33378)
                     /locus_tag="RD508_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDT7735847.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33386..34072)
                     /locus_tag="RD508_001237"
     CDS             complement(33386..34072)
                     /locus_tag="RD508_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7735848.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34078..35151)
                     /locus_tag="RD508_001238"
     CDS             complement(34078..35151)
                     /locus_tag="RD508_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7735849.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35373..36047
                     /locus_tag="RD508_001239"
     CDS             35373..36047
                     /locus_tag="RD508_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7735850.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQPPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36052..37392
                     /locus_tag="RD508_001240"
     CDS             36052..37392
                     /locus_tag="RD508_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7735851.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMATIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37541..38527)
                     /locus_tag="RD508_001241"
     CDS             complement(37541..38527)
                     /locus_tag="RD508_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HDT7735852.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDENLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            39251..40282
                     /locus_tag="RD508_001242"
     CDS             39251..40282
                     /locus_tag="RD508_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7735853.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            40391..41923
                     /locus_tag="RD508_001243"
     CDS             40391..41923
                     /locus_tag="RD508_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HDT7735854.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIISLSPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            42062..42874
                     /locus_tag="RD508_001244"
     CDS             42062..42874
                     /locus_tag="RD508_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HDT7735855.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            42864..43349
                     /locus_tag="RD508_001245"
     CDS             42864..43349
                     /locus_tag="RD508_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7735856.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            43372..43917
                     /locus_tag="RD508_001246"
     CDS             43372..43917
                     /locus_tag="RD508_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HDT7735857.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(43990..45633)
                     /locus_tag="RD508_001247"
     CDS             complement(43990..45633)
                     /locus_tag="RD508_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDT7735858.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(45762..47990)
                     /locus_tag="RD508_001248"
     CDS             complement(45762..47990)
                     /locus_tag="RD508_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7735859.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            complement(48023..48502)
                     /locus_tag="RD508_001249"
     CDS             complement(48023..48502)
                     /locus_tag="RD508_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735860.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
BASE COUNT        14819 a         8979 c         9169 g        15738 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata ttatacaaag
    10681 tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc gtcatttttc
    10741 catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt actttttttg
    10801 tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata tgaacgaatt
    10861 agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca cagataaaca
    10921 ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca tatgtacgga
    10981 tacattttcg gaccgattaa ttttaaccat tctgtttatt tgcttaccta ttagatatca
    11041 ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt ttagttcata
    11101 ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt tgatttgctg
    11161 aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac accattttcg
    11221 tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc agttaaataa
    11281 gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat acgtgcagta
    11341 ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata agcagcatta
    11401 cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc tttttctaca
    11461 atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac ttctgaatca
    11521 ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa tttcaatgcg
    11581 atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac acgtgatgtt
    11641 ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt tgaagcaaca
    11701 acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg catgattgac
    11761 gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat accagctgtg
    11821 ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac agccacattt
    11881 tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc tttttcttga
    11941 ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc ataagcgata
    12001 cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt tttcatgaat
    12061 aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct tgtttattca
    12121 ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa acgaattcct
    12181 gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat aatacaacca
    12241 aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa taagacagca
    12301 atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt cttaatgttt
    12361 atttctccat tcattgggag tacatgttga atacttcttg aataatttga ataaagaagt
    12421 cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg tttcttgaat
    12481 cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg aagcatcaaa
    12541 atacattttc aatttattac taagatagac cggattgtag ccaaaatgag ctgctgtttc
    12601 ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa gcatctcatt
    12661 ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag tcaattcgat
    12721 cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg tatcaaaata
    12781 aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc cgcgaaaatg
    12841 aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag aagaaagtag
    12901 attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt cttttaataa
    12961 gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag cttctttatc
    13021 aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa tttgtaaaca
    13081 tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg gaacttccgc
    13141 atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc ctcggtggat
    13201 ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca ttccttgttc
    13261 acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat tcagctagtt
    13321 ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca cgctgtactg
    13381 ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg gacatgaact
    13441 tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga taagcgctta
    13501 caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc tgctgtcagt
    13561 ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta tgtcagctac
    13621 ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct cttttatggt
    13681 cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa aacaaactgt
    13741 gatcatcgga ttagtgattg catcgattta tggtatcctc cccctcttct cacaaagtta
    13801 cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga tcaattcttt
    13861 ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta tgattggttt
    13921 tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag gacagctagt
    13981 acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta ttcttgtctt
    14041 gtttgttttg tttgttccta cacctgaaac aactgaactt caatcacatg gcacagcccc
    14101 aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt ttctcttgct
    14161 ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga cgacttattc
    14221 tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg caagtatggc
    14281 tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc ttacactttc
    14341 tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc tgtatgtgat
    14401 tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt acttattcaa
    14461 ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa tcttattggt
    14521 tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct cttttgcttc
    14581 tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt tgattagcgc
    14641 gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa gagtagatga
    14701 agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta aaatgacaaa
    14761 tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc gccatggact
    14821 gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact ggtacatgga
    14881 tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac cttccatgtt
    14941 taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac atccatgtgg
    15001 aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag gacatacatc
    15061 agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg gctggacagc
    15121 aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg atatcgcaaa
    15181 agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg aaacggagat
    15241 tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag aactaatatc
    15301 tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg tagaagctat
    15361 ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga aagctcgtaa
    15421 acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc aacttcaagt
    15481 ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt cttctttact
    15541 gaatcagatc tggtcagtat cagaagaaac cttcaagtta tgtagtgatt tgttttttat
    15601 cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat cattcatgat
    15661 caatcaatat cttttttttg acgaggaaat caataaacga acgatattag cattaagagg
    15721 acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct tgtggttgat
    15781 tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca tcgtctaccc
    15841 taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag ggtttattta
    15901 tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag aaggaacgct
    15961 tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt gcggagatat
    16021 cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc aagaaaaata
    16081 tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg gcgcttttat
    16141 cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt tcgctgtttt
    16201 attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct tattgaatga
    16261 cactatcaca cagattacta ctccatattt caaattctat gaacaagatg ctttatgcaa
    16321 actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag ggatgttatc
    16381 tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa atgaaaagta
    16441 cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag caagcccaat
    16501 ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt atgaagaatt
    16561 tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac ctatcaaaga
    16621 tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg atagaacagg
    16681 cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc cacttgtctt
    16741 aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat atcagaagac
    16801 tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc ttaattctgt
    16861 tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa tacgacaagt
    16921 aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc tagtttccca
    16981 agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc gattttaaga
    17041 tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct attgaaagca
    17101 gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc agaagcagct
    17161 ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa gcctatcata
    17221 gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa tacagcatta
    17281 ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg tacgagtttt
    17341 ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac cccttgaagg
    17401 acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat tacagcgttg
    17461 tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc aagtgcgaca
    17521 tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa gctgaaactt
    17581 ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt tccgatccat
    17641 ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt gtttccagtg
    17701 atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt tccttcgaag
    17761 accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac taaaatgact
    17821 gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa tttatatctt
    17881 gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa agcagtaggt
    17941 gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac tactccttga
    18001 gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact gattaaacca
    18061 gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg gatcacttct
    18121 gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac gaggatggag
    18181 ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag ttcctccctt
    18241 gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt cttcgctgtc
    18301 aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg tatctttcaa
    18361 agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa catccgtatg
    18421 acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt tgatgttcat
    18481 ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt tcatatcatt
    18541 cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt aataaatctt
    18601 gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga agatgtgcct
    18661 cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga ttatcaagca
    18721 gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg ccatcttctg
    18781 gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca tactgctcca
    18841 cgcgctcgat catagctttg atataacttt cttctatttt attttctgat aatagcggct
    18901 gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat tggatcattt
    18961 cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct aaaagtttgt
    19021 tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct tttaattcga
    19081 tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat cctggtatca
    19141 gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc atgattggat
    19201 gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta gaaaaaataa
    19261 tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc tctgtaaaaa
    19321 agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag ctaatgccac
    19381 ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc gcttttctga
    19441 tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg ctcttcccta
    19501 ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa gcatattgat
    19561 gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata cgaaaatagg
    19621 cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca aattctacgg
    19681 ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa aaatcaagtg
    19741 caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa aatataatct
    19801 ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta atgtcagtga
    19861 ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt tttccaattc
    19921 gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt gcgaatcgaa
    19981 gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa taatcaatgg
    20041 aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc atcaaacgag
    20101 cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc ctaaaaccag
    20161 ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt atctttttga
    20221 tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga aaaacagaaa
    20281 cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct tgttcggtat
    20341 acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt gctcggaatt
    20401 tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat tgtttgatcg
    20461 cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt tctcttggtg
    20521 ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac ttatattcta
    20581 gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg atttttttta
    20641 cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg accaaatgtc
    20701 tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt ttttgaggtc
    20761 agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt ttcaaagtga
    20821 ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa agctgtttct
    20881 ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc ttctgtttca
    20941 ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat tgaacctctt
    21001 aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag tagttctata
    21061 ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat tcttacaaat
    21121 atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca aaattttcat
    21181 ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta atgtctcgta
    21241 aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt cttcatgata
    21301 actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat cgataccaaa
    21361 gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat cttttgtttg
    21421 tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt tgatgcggaa
    21481 ataactggat tttatcgaaa ttttcatatt tccatagaaa aaatccagat cgaagtaatc
    21541 attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat ctggttcgcc
    21601 gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat agctgttcgc
    21661 agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat aatgcatttc
    21721 tacttctaaa atatccccta attttccgct ttcgattact ttttggactg tcaagaagtc
    21781 agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt ttgctaatgc
    21841 aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta gtacattctt
    21901 accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg tagtgatgac
    21961 aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat attcgatgtc
    22021 ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat tgattttgtt
    22081 cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat tgccaagata
    22141 agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata tcctagaaaa
    22201 gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac acttgttatc
    22261 attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga tagtagcgga
    22321 accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt gaagaaaaac
    22381 taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac atccgtagga
    22441 atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg tatacttccc
    22501 attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa gaattccgtt
    22561 tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg attgatccta
    22621 attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg gcggatttat
    22681 cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta gatcaaatcg
    22741 gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat tctcaaatca
    22801 cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc atggctgaag
    22861 aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc gccattttta
    22921 ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg aagcatgtag
    22981 aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa caggctgata
    23041 tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact ttctcctctc
    23101 aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct caaaattttg
    23161 aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc cttcttaaag
    23221 aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag tgtttgatag
    23281 gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac ctcagcctgt
    23341 ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct aacttctgtt
    23401 tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca gtatacatgc
    23461 agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta cttctttttg
    23521 aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat gactgttgac
    23581 catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga ttctcagatc
    23641 ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga gtgtccgtcc
    23701 attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg tgaacaactt
    23761 tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc cccccgtagg
    23821 ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat tcgtttcatc
    23881 aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg tatgtttctc
    23941 aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat ctgcacctgg
    24001 atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt ggattttagc
    24061 catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga tctgctgatc
    24121 cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta ttcctgagag
    24181 aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca ttcgtgttct
    24241 ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc cgctgctcct
    24301 ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca aagtacagtc
    24361 cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc ttaccgcctg
    24421 ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc aactgtcctg
    24481 ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat ggaacatatt
    24541 tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct gtcacatcga
    24601 ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat acccagctga
    24661 cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct tgatcacgaa
    24721 cgacgaattc tgctccagca agtgtttgat ctgatgtaac gtcaccatct actttaacaa
    24781 atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt gtatgcccgt
    24841 tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg ttcaaatgca
    24901 tatagtaaac aaatttcagc gtaccaccag gagtgagtga aggaatataa ttcgagtcaa
    24961 ctgaaaccgt gaatccgttt gtttgttcag tgacagaata atttgttgga tcgatttctt
    25021 tatccccatc atacaagaca tacgcatacg ttcctgaagt ttcatgatca aatgtcaaag
    25081 cggcgtcatg agtatcaatg agtttgaatg tcgtgtactt gttttgtgtt ccttctttat
    25141 cagcgatacc taaaggaata ttgacagaga tctcatattg gattttttct ccgattgcga
    25201 catcttttcc attcaattga ggtgttgttt tatcaacttt ggacgtatca tttttgattg
    25261 tcttttctac aggagtttga ctatttgcca agatctcaaa cggcgtgttt gtttgattat
    25321 caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt ccaacctcta
    25381 aatgattgac gatcaactga cctttttcaa tcgttgcctc ggcaaagtca ttgttgccga
    25441 tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatccgtt gtccaagtgt
    25501 acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtcttcct tcttctttag
    25561 aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt tttgtaactt
    25621 tcaacgttcc atcattaccg actgtatttt tagggtagag atggatagta tctagttctt
    25681 ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca gggaaagcta
    25741 aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc gtgtagactg
    25801 catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca gcatctgtcg
    25861 ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt gctgcatcca
    25921 cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa actgaaaatg
    25981 aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg ctgttttgga
    26041 ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga gctgctgtct
    26101 cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa ataaggaaaa
    26161 ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc ctgttctttt
    26221 tttgataaac aaccagattg caaagcttgc gaataccata ccaacaacgc ctaaaagtgt
    26281 atttttcgtt tcgtttgttt ttggaagaaa tggacggcta ttttcttttt tattgactac
    26341 tttcaatata ctgtccgcct ctttatcctc agaaagaaaa gttgaaatgg taaacggaat
    26401 ttctgtttca cttaaaatat aaccagaagg tgcttcgatc tcttttaatc gataacttcc
    26461 tgttttcaac ccggaaattg aaaaagcgcc atttttatcg gaaatcaggt gaagcgcatc
    26521 tgattcgttc tttgtccact tgtatccgtt ggctgtttgc tggaggtaat ttcctgcttt
    26581 gtttttaata aggaatactg cgccagctaa tcgtttatct ggtttatttg tctcgatttt
    26641 gacaaattgc ttactccctg tatatacaga gactttcttt gtactgatac caaaaccaaa
    26701 atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt gctgtactgc ttagctgcat
    26761 ctgataagaa atggtcagtt tttttccagc atatttttcc aacgaaggga tcgaaaataa
    26821 aacatcaaat ccgtgaggtt ttttgtgtat gacaaagcct tctgtcagct tttctccatt
    26881 cgatgaaatc gttaaactat taggtaaaaa cgttaatgct tcatccgcac tatctgacaa
    26941 ttcgaacttt tgatagtcaa ggatatttac aggaattgtc gtatgcaagg aataagtgat
    27001 tttttcacca atcgtaaaat catttctagg ctcttctaat accttctcaa aaggtggatc
    27061 agggtagtcg ttttcttcat ttttaggata caaatggata gttgaaagtt tttgattgtt
    27121 ttgtccatgt acaggaagaa caactaccat attctctgcc ttttctttga cgacttctgg
    27181 tgctttggat tcaatgaaaa gatacgcttt atctcttttt tcttgatctt tagcggccag
    27241 agaaaaagaa gcgataccat cttcgttgtt aagagttgta gttgttgctt ctgcggtaaa
    27301 cgtaccggaa gacgcaccgt tttttgcgat ctctgtttgt gcttcttcta ccgttttgcc
    27361 cttttcccgt agatggtaaa aagaatctgt gacatcataa acttggaatg tgacaccatt
    27421 taatcctcga tacgtttgta ataacgcttt ttcttgtccg tcatttggat gatttttcgg
    27481 cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc tgaaccattt ctgtttctgt
    27541 ttctgttgct gcctgagtaa aagctggttt aaatagtaac aagaagagac acatactaag
    27601 ccaaccaagt tttttcatat ttagctgccc cctctttctt ttttcaaaaa aagataccaa
    27661 atagaaaacg cacaaccaat catccctact agatagattc ctaaacggcc aattcctccc
    27721 gtttcaggta atggtacttt tgcctgattc gtgatgtcta aagaaatctg gttgtttttg
    27781 gctcctggtg acagaacaga ttcatgatct tgtccatcca cttgaattga cccatcttcg
    27841 tgtataacta tagtaactgg ctcttttaga ccttggtatc cttctggtgt aaaagtttcg
    27901 gtcagcgtat aagttccagg ttttaaattt tcgaatagaa aggtatctgt ttcttgtcca
    27961 tcttttggcg attctaagtc catttctggt ccctgcagtc tgaattttgc tccttttaat
    28021 gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa acgcttttag tcgattttga
    28081 tgagtgagcg tccatacatt atttgtcatc tcggtatttt ttcccgtgta aatgattttt
    28141 ccatatttat cgatttggaa ttcataattt cccggcgaag tatcatatcc ggcaggacca
    28201 gctgtttcaa cgactcggta tttaccaggt gtgagtgaat caaaactggc aagacctttt
    28261 tcattcgttg tttggctgtc aattggctga taagtaccat ttgcttcttt tttctgtagg
    28321 gaaaatgctg ctcctttaag atttatctct ttgtccgtcc cttgcatcgc atacttacgt
    28381 actgctacag gaacttcaac aaaaggattt tcaatagtca actggatcgt atcatcggaa
    28441 gtagtgactg tttttccatc aatggttacc gtaccatcag aagcgatctt gatttcccaa
    28501 gtagtctttt tgcttaatcc atgcccttct ggagcttttg tttctgtcag cgtataggtc
    28561 atttcttttt gcaatttgac attttctgga agagaatagg ttccgtcgcc atgatctgtt
    28621 agtaaagtat caatagaatc tcctgttaat ttgaagacag caccgatgag attcttttca
    28681 cctgtagagg aatttttcgt tattttcaag tttaacggtg tgaattgttt agtatttttc
    28741 catgtcattg catctatttg ttgagaatcg tatcctggta caggtaattc tttgattgtt
    28801 tggtaactga atgcttgacc ttgattattg tattgaggta gtgataatat ctcttgataa
    28861 ctttctccgc tatttgcaga taatttgtca atgtctgcac gttcccacga atttgtagta
    28921 tctttagctg gtttaatgat tcgaatatat ccgtttttcc aagctgcagc atttgtcgta
    28981 tgttcccgtt gaatctcaaa agtaacttga tctggacgat cagctagatt gttgtcaaat
    29041 tcttcccata actttttgat gtgaagactg actccgggag ctttagcaga tggtataccg
    29101 aattcagcta attcattggt atcaatgttt ggctggaaag ttgtcctgcc gttcatttga
    29161 taccagaaat ttggatggaa gtcctcattt tctgtttgga ttctcacttg gtaatggatt
    29221 tggatttctt ggtcttttcc taaatagatc tgattgctct tgatggtatt tccttctatg
    29281 gaaatagatg gagtgaccgt tgtaggactt gtccccacac tcttgactga aagtgtacca
    29341 ggctgataaa tgaatggttc tgcgattgga tcatttattt gtccattgct tacagttgct
    29401 gagatctgta cagctttttt ggctaggtat tcagagatat ctgttgcatg atcagctgat
    29461 tcatagtaaa gatcgccttt ttcatctgat gaaaccattt gtcgcatacg agactctact
    29521 tctgcttttg agagaccagc tgccggatcg ctttgaagtt ggatgccaag accatgtatt
    29581 tcgattcctc gttctttgag tgccatcgct tctccgatgg ttgcgataaa cgtactgtcg
    29641 attcttctgg atagattgtt ttggtcaggt gcatcataga ttcttgagat tagagaagta
    29701 tttcccggcc gatcttgcgt attagaaaac tgagttccgt aataattgct gcttgattgt
    29761 gcgtgtaccc gctgtacttt ataggaaaat gttggtacac aatccgtcag caaaacgatc
    29821 acttttttat gtccatttgg aacggatagc atgcttcctg catctcttag tgctttttgt
    29881 gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt ttacttgatt tttcactgaa
    29941 tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat atccttcgct tgagtagccg
    30001 acatatccca tattgatttt gtctgtgata ccgctatctg ctaaagtatc gacaaaacga
    30061 tcgacaccaa tctttacttc accgatccga ttattgtcgt tcatacttcc tgaccagtct
    30121 acgaccaata cgagatcaag aggcgtgata tctttttgta catttccacg agcattcaaa
    30181 taaacatcaa acaatccggg tgtacttgtt tcctttgcat actttcgtat cgcatagtct
    30241 gcttgattac cggttcctcc atattcgata tacgaatggg tccgatcatt aggatctcca
    30301 ttccaagaat ttataccatc ccattgattt gttccgtttt tattgccttg atgatcaaga
    30361 acatttgtat ttcctgtagg ttgccaactg gctttaggat aagtgccctg atcatctgtt
    30421 gtatattctg taggaatcgt ttgattagat ggcacactca cagctggcaa ggataatgta
    30481 ggcaatgtaa atgggctgac agaattttcg ttttcttttg atgattcttc ttctatttcg
    30541 tctggctttg gtactgacac atctgtatct ttcttatttt ctgtctcatc aataatgtca
    30601 tattctttat tatcgacgat cagcttgttt gcctggctgt ggtaaagtgc tggatcgatt
    30661 ggaaaactca gatcgatagt ttgtttagtg tttgatgaga tttccaacgt aattttcccg
    30721 ctatttacct gataagcata gccatctcct tcttttcttt ccacatcact taagtaattt
    30781 tcgactagac caatttcttt ttctatcttt tcagcactgg tgttattcgc atttagcttg
    30841 atgttcagtg ctttttttcc agactgatcc gaaatgactt cagctgaaat tgtttctaaa
    30901 actgttggat catctgtagt gtctgctatt gcagataatg gcacaaagtt tgataaactc
    30961 aatattatca gcatgaaaat aactttcagt ttcttccctg tggtcgtcat ttttcccctc
    31021 ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt attaaaataa acaggcgtta
    31081 cataatttta tttattttaa tatgataatt attatacgaa gggcgctaaa gggaatcaca
    31141 ccaattttca taccaattgg tttcatttat gaagttgatt ccttcgatta atgagcgttt
    31201 cattgaaaga aaagggttga gggagaaaaa catatgatca ggttgttgga atgaaactat
    31261 agaaagatgg aaaaaatcat tcgaattctg tccatttctg acaagtggat gactaaaaaa
    31321 gaacttgcca aacgaattgg tagttcagaa tctacatttg taaggtatat cgaagagatc
    31381 aaaatccgct ggggaacgga tgtaacgatt caatcttcac aaaaattggg gtatcgtctt
    31441 gaacatttga atgtaccagc ttatttaaat gttctgatgg aaatgtcgca aagttctaca
    31501 aacagtcgtt tattaaatga gattattgtc aatccgggta aaacgattga gtattattgt
    31561 gaaaaaattt ccatcagccg gtcttctttt acacgtaagt tgaaacaatg caatcaaatt
    31621 ttagaaagct atttattaaa agtgatcgtt gaccaaggtt ttcagttaac tagccttaaa
    31681 agtgagctcc agttgcgtat ctttgtcacc tttttctttt taagttacta cggaagacgc
    31741 acgttgccat ttccaatcga aaaaaagaag atcaaagaaa ttatggtcaa gaataattgt
    31801 cagatgaatt tgtttcagga agaaagccca tatgagcaat ctttctttat tatgtatttt
    31861 gttgtgcatc tcatgagaga atcccaagga actccatttg aatggaaagc tggagactct
    31921 tatgtacagt tgataaatat cgataaaaaa gacttcttaa tcttgaaaaa tctcttagga
    31981 aaattgaagt acagcagcta tataaaagta gtgaactatt ttgtcaatac gattttttca
    32041 gaattttcgg agaaagaaaa aaatgaaatc agtgagcaga tacgaaaaaa tatgtcctac
    32101 tgttcgtttt catccgctga ttgcaaagaa aaaaacgaag aatatgttgt tcaattatta
    32161 acgcaaattt attttttctc ccgtattttc ccatacgata cgactcattt gacgatccgt
    32221 gcaacttact ttgcacagca gatgcaacac cgccagatac gtctatatgc tggatttcgt
    32281 gcagaacttc aattttattc cactctactg aatcagaatc tgatttatta tttatctagc
    32341 tatatctttt ggatgcttat cggtaatcct gaaattcacc attatacttc tgataaaaaa
    32401 atactgatta tcagcgactt aagtcttcga catagtcaat atattgaaga atatatcagt
    32461 gatattcttg ctgtgcataa aattcactct gagacaactg ctattactga agatcagctg
    32521 tcgaaataca atcttctcga gtatgatctg atcgttacga atcaacccat tttgaatgcc
    32581 catgttcctc atatattgat tgatgatagt gtgtcattcg caaatgaaga agaactcatc
    32641 cgcttattcg agttatgaat aatcaaaaaa cagctatgta taaaccaccc tgataaaaat
    32701 ttcaggacaa atacacatag ctgtttcttt ttattgtatt ccttcagcaa tccaacgaga
    32761 tttatagcga aagtctttta acaactcttc ttttgtccaa ttatttgcaa tgagatccgt
    32821 caaagtgttc attacgaggg tcatggaaaa gtataggaaa ctaactgctt cttccgacga
    32881 ttgaatggag aaatgattga ttcttaataa ttccagccat ttttcgttca ttggagaatc
    32941 agccgatagt tctctacgtt tggttgtctg ctgatcattt cgctgggtta acaagtataa
    33001 cctttgccaa tagatacttt cgtgatctaa gtcgcagcac cactctaaat atttttcgat
    33061 ccccaaaaag aaatgttgtt tgttttcgct aatgaatttt aagatatctt gatggactat
    33121 gtgagaactg cttttgatcg tatacaaata agcatcttcc aaatcttgaa aatatttata
    33181 aaaagcaccg cgcgacatcc ccatcttgtc aacgatttct gagactttga cttggctgat
    33241 gtgctgtgag caaaatatct ccagtaatag gtcatcgatt ctctgtttct ttgcgttcga
    33301 taaattgaaa aaagtttctt ttggcatcca catctctcct ttatctctga ttatacgtgg
    33361 atagcccttc attgtcatga aggattcatt ccttcttttt ctcttcttct gtcaagtacc
    33421 catcttccat tcgataaacg cgatcactcc attgaatcat acggacatca tgagtaacca
    33481 taatagtcgc tttttgtttc tcatgagctt ctttaactag taatttgacg acttcatatg
    33541 catgatctgt atccaaacta gctgttggtt cgtctgctaa gatcaagctt ggctcattat
    33601 ataaagcgcg agcaattgcc actctctgtc tttctccacc agaaaggtct ttaggataac
    33661 tatttttaag tgactggata tctaaagatt gcagcaagga atcgattttt gttgaatctt
    33721 ctttttttga agtaacttgg tcaactagtt caaattgttc ctttaccgtt aaaaaaggaa
    33781 tcaaattaga gctttggaga ataaatccta tttctttaaa gcgtaaatct gctcgttttt
    33841 tttctggaag ctcagttagt gagtgaccgt tgatcactat ttctccggaa gtcggtgttt
    33901 gcaatcctcc tgaaatggta aggaaagtac ttttacctga accagaagga ccaatgatgc
    33961 tgacgaattc tccttccttt acataaaaat caattgcttt caaagctgag acctttgtat
    34021 gaccagaacc aaatgttttg gtaacttttt tcatcgttaa tatttttttc atttttatta
    34081 acctcctatt gctgtaattg ggtctacttt ggttatcgta cgtatcgaaa acaatccgcc
    34141 tagcattgcg acaatgatca aaatcccact atatagcaac cattgtgacc aaaaaacagc
    34201 aaaaggcatc gcgcttggta aaatcagact agtcaaataa gcaaacaaaa gagcaagcag
    34261 aacgcctacc accccaacaa taaaggactg tgctactaaa gatttagcga tgaagaaatt
    34321 tttgatccct tgtgctttca ttactccaaa aatagcagtc ttctgaagtg tcatcacgta
    34381 catgaaaata ccgaccacgg cagcaaccac taagaacaaa aagtatatca tcgcatttaa
    34441 ggtcatattt tgggcagaat agccaggaat actttcaatg aatgtcccaa tagttaataa
    34501 ctgtagaccc ttcgatgctt tttctttcga aattttagct gaatccttta ttacgatccc
    34561 attgatcggc tgttcttctt cagaagcaaa cggctgttgt ccatacttca aagcagtcca
    34621 cgtatctagg gacgcataga tgacgggaga aactgtgtaa taagtttcag gaaagatacc
    34681 gacaatcgtc aaaggatcgt cgtaactgcc aattttgatc gtatctccaa ttttatagcc
    34741 tgaatcagcc agattttgag agatgatgat ttcattcttt gttttaaatt catgcccttt
    34801 cgtgagtttt ggtaataaaa atgcttcttt cgttgtgccg aaaactgtaa cattttcttt
    34861 gttttttcct ttgattgctc cgctgtacaa tccgattggt gctttctctc ctccttcaat
    34921 gtatttcaga tctcctcttg ttaattgtga agctgcaaat acttgatttg catcctccga
    34981 caaaacaatc tcttgtgcgt cccaatcatc gattgctttt ttaaactctt ctgaaagtcc
    35041 attcgctagt cctgacaaca tgaatacgac atacgcaatc aagaacataa taccgacgat
    35101 caagccatat cgtaatttag aatagcgaat ttctttgata gctagaaaca tttgtttttc
    35161 ctccctatga tagattgata gtgacaaaat gtcacttgtt gaatagtgta actctaaagt
    35221 gacaatttgt cacttgtgtt gtttttttct tatcaataaa ttgtctaaga catctttcga
    35281 taaaacctta acatgagtca taaaaaattt atttaagcct tatttatgct ttccatgata
    35341 aactaaagtg accaaatcaa tgaggtggga aaatgattaa actattagta gtagaagacg
    35401 ataaagtatt atccaataat ataaaagaaa tactcgctgc aatcggcgag ataacacaag
    35461 tttatgatgg tagtgaagga ctgttcgagt tggaaagtgg agtttatgat cttgcaatct
    35521 tggatttgat gatgccggaa atgaatggat atgaagtgtt agcaaaaata cggaaagaaa
    35581 aaatacagcc tccagtattg attttgactg caaaagatag tttggaagat aagattgaag
    35641 gatttgaacg aggtgcagat gattatctaa caaaaccttt ctatcgagaa gaactgatca
    35701 tgcgcgtgaa agcattattg aaacgctcgc taggtctctt tgatgaaaat gttctgaagt
    35761 ataaggatat cagttgtgat ttaaaaagca atgaagtctt gtataaagaa caagttttgc
    35821 ccatacaagg aaaagagttt gaattgctcg tttatttttt acaaaataag ggaatcattt
    35881 tgacaaaaga gcagatattt gaccggatct ggggatttga ttctgatacg acgattacag
    35941 ttattgaagt ttatatgagc aacttacgaa aacatctgcg aagtactgga ttggataaag
    36001 aaatcaaaac cttacgtaat gtcggttata tactgcaaag ggtgtgatgc aatgaatgga
    36061 gatattacac gaaagcaacg tagtcgcttt tttgcgacaa atgtagcagc atttgctttt
    36121 atcttttttc ttttgggatt cattacttta cagatattaa accaatctgc atacagagaa
    36181 acagatctgt cattagagaa aataaatttt gattctcgaa cagtacaatt agagatacaa
    36241 agatatcagc aaggcgatcc ctttttaaac ccgactcaaa cggaacaaaa cagaacaaac
    36301 atggaacagc cattaatgga accatcaaat gaccgtttta acactcaagt gatcttgtgg
    36361 tctaaaaatg gtgagatatt gaataaagca gctattggtg ggcgtttcaa ccaaatcaaa
    36421 gaattaaaaa tggatacgaa aaatctgaat accatccaaa atattgaatt aaatgaagac
    36481 agtggctcat ctgccctctc tttccgttcg attacgaaaa aagcggagac gaatcaagat
    36541 ggcgttgcct acatccaaat tttagaaaat acaaatcaaa tcaagaattc attagcgact
    36601 tttcgcacga ttatgatttt gtgtatgatt gttttttgga ttctctctat tggtatcagt
    36661 tattacttgt ctagtctaag catgcgccct attattcttt cttggagaag acaaaaagaa
    36721 tttgttgaga atgcttctca tgaattgcgc acaccgttaa cgattattca aaatagtttg
    36781 gaacatcttt ttaccaagcc taatcatact attattgaag aatccgaaag catcgctcaa
    36841 gcattgtcag agacgaggcg cctcactgga ttgacttcgg atttgctgac aatcgctcgg
    36901 aatgattctg atcagcagct gctttcaaag caaatgatca atacacaaga atatatcgaa
    36961 caacttgtta aaccatttca agagatggcc accatagatg gaaaagagtt tattctccat
    37021 aacgatgcaa cattagaagt accaattgat gaaaaaaaaa tccatcaagt tttggttatt
    37081 ttgctggata atgcattaaa atatacgaat ccagaagata agatcatttt ggattcatct
    37141 gttaaccata aagaatggct gattcacgta aagaatactg gcccttctat cagtgaagaa
    37201 gatcaagcaa ggatttttga tcgattttat cgggaagatc aatctcgggc gaaagagact
    37261 ggcggatacg ggcttggctt ggcaattgca aaacaggtaa tcgaacagca tcatggacag
    37321 atttctgtat ccaattatct tccacaagga gtcgatttta aagtccaatt gccgttgaag
    37381 cctaaaaaat aatgcttatc cctaaaaaag ggctgtgaca aaaatcttgt cacagcactt
    37441 ttttgttgcg aataaacggt gttccagaag tagcttcttc ggaaataagc cgaaatttct
    37501 ttaagctgac cacttctgtc acaacctctt tagcttacgc ttacgatttt ttattgcggt
    37561 cttcaatgtg tacatcaccg cttgtgtcaa tatccaattc ttctcggcta acatcttctg
    37621 tcactttttc aacatcttca tgttcttctt tatgaatccc aacttcttca cgaataactg
    37681 tatgtttgct tacatctact tgctcttctt tgattgggat agtaatcgtg tcatcttcca
    37741 agttttcgtc tgttccctgt gaagattgat ctgttactgg tttgcgttcg atgacgattt
    37801 cttcacgttt gaccggtact tctaccgttt cagtatcgtt gaccacatgt ttgtggatgt
    37861 cgacttctcc agttgtcaca tcatgtgtat ttacatctaa tttttcttct tttagttgaa
    37921 ttgtatcatc atctagattt ggtttgcgat cgatgtcttc agtcttgctt gtacccattg
    37981 tatcagtctc gccaggtacg tccatcggat cagttcctgg tgtcatattc aatggatccg
    38041 ttgtattttg aaagcctgtc gtgccaccta cgtccattgg atctgttcca gtgccagttt
    38101 ctaatccagt ccccattgtg cttgctgggc taacagtatc ttgtgtatcc attgtatctt
    38161 ctgttgtttc tggctgacga tagcctttta ctgtgatgac aaattttcca tcagaaatat
    38221 ctcctctata ttgatataaa ggatcatttt ctggtgtagc cgtctcagaa tcataggtat
    38281 caaaagaaaa agtatctttt attttttccc ataaagaacg gtcttcttca ccatccatcc
    38341 gattttcatc tgtttcaaca tctataccag acaatccgtc aaatcctagt ctagatgctg
    38401 cttcatcagt agtataaata acgatatcat ctcgttcata cccttcgtta cgcaaccgtt
    38461 caattactga taatgcttct tccctcgtac tatagcttcc gatgaccgtt aaatttttct
    38521 cttccatgta aattcctcct agcaaataga tttatgattg gtatattgtt acttataaat
    38581 ttattctata ggagacgatt gttttctaca aatatttaga ttggaatttg attaaaacaa
    38641 tttaattgaa atttgaaaac atttatgtta atgaaagtca tattctaata aaatgtcatt
    38701 tgtttctata tgaattttta tgaaaaattt catataattt ccactcgttg tgatggttta
    38761 atttatccaa tccatcaata agcaaacaac ttatataaaa aaggattaat tctcaatata
    38821 attgctccta ccatagaata aatcttcatg taaagtaatg aagtaccaac tatttctaat
    38881 acttctttaa gaattatccc aacaatatcg ttagacaaac cattattgaa taaatggaga
    38941 gccaatcgat tctgaaaaaa tgttttctaa tttttcggaa ataaaagaaa gagcctcctg
    39001 ccattagaac gaaccaaatc catttcattg ctcatgaagt aaccacatag ctaaaaagag
    39061 gataaatcaa ttaaaagatc aaaagaatga ctgcactaat aaaataacta aaaatgtatc
    39121 ttcttacttc atatctttta gctagtactt agttaaaaat ttgcttccta agatcaagac
    39181 aaactgtcta tcttcatttg atgaaatgcg gtaaaatata gaaaatgaac actattggag
    39241 ggaatttgta atggacagca aaactagaaa acaactgcaa gaaaagttaa agcaacgtac
    39301 acacttgctc ccttccgtct ttcaacagtt tttagaagaa aatcgttctt ccctttcatt
    39361 aggcagtcgc tatgaatacg caaaagattt tcatctgttt actgattatt tgagaaaagt
    39421 attttctgaa gaagtggatg atcagctgat tatccattta gaaaaacaag attatcagaa
    39481 tttcttagct aaaatctatc gacatactcg ttcgttccaa actacagcga accaagaaac
    39541 ggagcaattg tttgaaaata gctattacgg gatttcaagg aagcaatatt cattaaatca
    39601 ttttttacga tttttgtatc aaaaaggact gattgaagaa gagatttctc ttttgggtac
    39661 aagtttaccg gaaacaacca aagcagctcc gcgatatatc gatgcagaac ttttcaaaga
    39721 ttttgagcat ttgtttatcc cgattgaagg ctttcaaaca agcagagaag ctagctttga
    39781 agaaaagaat agaccgagga accttgcaat tactgccatt cttctgtatt gcggattaaa
    39841 gatccatgaa gtagtagaac ttaaacgtaa agatgtatct ttgaccaagc agattcttaa
    39901 tctgaataga aaagaaaaca gactgaataa agtaccaata ccaaaagaag cgatgccatt
    39961 tctggagaac tattttaagt taacagcaca aaatacggac gaaaattctt ttgtttttcg
    40021 ttcctcacat gatcagcaaa tttctcctcg gactattcgc caaattttga gcaaaattac
    40081 agtatataaa aacgtatcgc cagaactatg cagaaaaaca tatcgttatt atgcagaact
    40141 atatttagat gatgctgacg cggtaaatta tttatgtggt aatcgatacc tctcatccca
    40201 ttcttttcaa gatatctggg aaaagatggt tgatttttct tatcacgaat tagcggcatt
    40261 cgttcgggtt tcttccatat aaaacaaatg tatgatcttt ttttcacaat aaactatgtt
    40321 attatataaa ggattatgtt acgattatct tgaatttgta tattacttaa caaaagataa
    40381 tggagtgtga atgatggaga ccataacgta ttcccctttg aacttattta cgaattttca
    40441 agaagctgca gctaactttt ccgagacccc gattatcttt gatgagccac tttcagcttt
    40501 cccagaatta ggacttgaaa caacttacaa aaaatgctgc gaaagtgtgt tgaaacgggc
    40561 ttatcaattg gctcatcttg gagtgaaatc cggagacaaa gttattattt ataagagttc
    40621 cgcttttgac acataccttc tagctgtttc tgtgtcttac cttggtgcag tgcctgtcat
    40681 gacttcttat catctaccaa caacaacaat ggaagtattt atcgatcgtt tagaagaccc
    40741 tttcatttta tttgatgatg agacaaaaaa gcgagtgaga gaaatttcaa atggaacaaa
    40801 atcaaaacag attcctattc tttatttaat ggaacaacct gctttgtctg tttctcaatc
    40861 atttttagac aaaaatgaaa tttcttatat gacccatact tctggtacaa ctggtatccc
    40921 taaacttatt tgtcattctg ctcattctat gggatggcgg acgaaatggc aaaaaacagt
    40981 tttcacaaaa atttcggaaa agaaattaat cgcttttcac atctctccag tgcattccag
    41041 attcaatatt ggtatctctt ctttgatgtc catgggattt cctatgatgc ctttagcaaa
    41101 cgcacaaagt tcaaaagttg ttcatatgtt ggaagctcac cggccaattg cactagagac
    41161 ccatccgaat aactttgttc agtggcgttt tactgctaag gagcatccag aagctttttc
    41221 gggtatccga tactatcact ccacttttga tgctataaac aaccagacaa tgaagacatt
    41281 tttgcgaacg tcgatggcac aggatgcggt atttcttcaa gtatatggcc aaagtgaatg
    41341 cggaccaatg attcttaagg ctcatacact agagagtttg aaaacaagtg atgcaagaga
    41401 tatgggcgtt ggactggaag acatgacaag cgctcggatt acagattcag ttgggaatgt
    41461 cctacctgaa aacacagatg gtcatataca attactgtct aaaggacggg ctttgactta
    41521 ttacaaggaa gatgcacggt tccaggaaaa tgtttatggc gattggtggg atagcggaga
    41581 ttacggtttt atggataagc atggccacct atttttgaaa gatcggcaag tggatttgat
    41641 cgaaacgatc aatagtacat tagctattga agacttttta ttagattcgt tagatttttt
    41701 ggcagaagta gtgattgtaa gggataaaaa tcattctcca caaccgatta tttctttatc
    41761 tcctgataaa gaaatggatt ggaatcgatg gtgggagcaa gtccatgaac ttcctcgctt
    41821 gaacgtccct atcatccgtg attttgatgc aatcccgcga acagctacaa tgaaagtgca
    41881 acggcttcaa atcgagaaag aattaaaatc acaaaagtcc taactattta aggaaagaaa
    41941 gatccatttt ggtctttctt ttctttttgt ttttttaaat tggatgagat aaaaatatgc
    42001 caattggctg tttttctttt ttgaaaattt cgttatactc ttattcatgg aggaaaatgt
    42061 tatgaaaaga atcttgacaa ttggcggttc tgatccattt gctggtggag gaatccaaac
    42121 agatttaaaa acttttgaga attttggtct attcggacta agcgccttga cttctatagg
    42181 ggcactagat attaatgagc gatttatgct ggaatctata tctttggaat tgcttaaacg
    42241 acagttagtt tcgattgata aaatgacttc attagatggt atcaaaattg ggttattgaa
    42301 ttcaagtgaa gcaatcatgg ttgttcgaga cttcataaaa acaaaacaaa atatcccaat
    42361 cattttagac cctgttttgg cattcaaaga aactgaagct gtgatcaatc aattgtatat
    42421 ttcgcagctc atcgaagaac tttttccact tgttacgatg attacgccta atttggcaga
    42481 agctgcttta ctttctggtc aagctcttcc ctcttcgtta acagaaatga tccatctcgc
    42541 taaagaactc actgcttcag gaacaaaaaa cattgtgatc aaaggcggca caaggatggc
    42601 tggagatgaa gctgtggatc ttctctattc aattgatcat tatgaggtat tttctcataa
    42661 aaaaatcgac actacaacag taaacggggc cggttgtgcc ttttcttctg caataacagc
    42721 gaatcttgtg ttaggggcag attttaccaa agcagtagca gaaagtaaaa aatttgttgc
    42781 ccattgtatt tctaatggcg tgctgatgaa cgatcatacc ggaagtgtct ggtctggcgg
    42841 tattcaaaaa ggaggaatga gaaatgaaaa ctaagcaatt aacgatctat gctatgctga
    42901 ttgcgttgac agttgccctt tcattaacaa ttttgatccc tgtaccggct acgaatggat
    42961 ttgtgacatt atgcgaggcc gggatctata ccgctgcttt tctttatggt ccaacgggtg
    43021 gattagttgt tggtgcttcc agtggtctat tgatcgattt gatttcagga tatccgcagt
    43081 gggcagtttt ttcattagtg atccacgggt tacaaggata tgttgctggt tctttcagca
    43141 aatcttctac tcgtatgtgg ggattagggc ttttattagg aagcttagtt atgatcatcg
    43201 gctatggtat cgccggttgg attttatatg attggccggc tggagtggct tctataccag
    43261 gaaacatctt ccaaaatctg attggaatgg gacttgcctt tcctataact gcaagtcttc
    43321 aacgtattca agcacggaag caatattaat tgaaaaagaa ggttttagaa aatgaagttg
    43381 tcagaaaaag aattaaaaga ccaattgact gaaatagtta atgacatatt ggctgaggca
    43441 cacttgaaaa aaggtgatct ttttgtttta ggatgcagca caagcgaagt cgttggagga
    43501 catattggaa aaaattccag tgcggaagtt ggtcaatgga tcatccgtac gttaaaagag
    43561 ttgttggatc ctaaagaaat tgcgctagct gtccaaggtt gtgaacattt gaaccgagca
    43621 ttagtagtag aacgaacagt ggcagaagca aaaaatttcg aaattgtctc tgttgttcct
    43681 gcactacatg ctggaggtgc ttgttctgtt gctgcttttg accagttcaa tgatcctgtc
    43741 gaagtggaac acgtagttgg acaagccggt atcgatatcg gtgacacatc aatcggtatg
    43801 catatcaagc atgtccaagt acctgtcaga cctcgtttga aaacccttgg acaagctcac
    43861 gtgacagccc ttcgctctcg tcctaaatat atcggtggtc ctagagcgaa ttattgaaat
    43921 gagtaattga cagagcaatc tgaaaaactt cctcgcaaag tccaactaat gaactttaac
    43981 gaggaagttt tacttgtttg ttttatataa ccgagcttca taaggtgcta gtatgccttt
    44041 agcttcaaat tctccgctag aggaatttga caagagtaat gtccaggact gatctgcttc
    44101 ttttggaagt tcatagtcag caagtgattc tgttaagttt accataataa gatattgttc
    44161 atcttctaaa tatctttcat agacataaag ttgtggatgt tcatgaagat attctttata
    44221 agaaccgtat atcagacctt tattggtttg tctaatgcgg atcatgttct tatagaattg
    44281 caggaccgac tctggttcat attcttgttg ttctacattg atcgttttgg tatttggatt
    44341 agtgatcagc caaggttcat gtgtagaaaa accagcatat tgttccgaag tccattgcat
    44401 gggtgtcctg ctgttgtctc tcgttgtttc acgaatgata tccaatgctt cttctcttgt
    44461 cttaccttcc gcaagcagcc ttttataaag tcttttcgaa tctactgcat caacttgatc
    44521 gatcgattca aagggcatat tcgtcattcc gatttcctgt ccttgataaa taaatggcgt
    44581 accttgcaaa aagaaataca tcatagcgat tgcttttgca gacatagccc aaaaatcggg
    44641 acgagtatct ccaaacactg aaacggcacg aggaacatca tggttttcca tatataaagc
    44701 gttccatccg ataccatcca atgaagtttg ccaagcgctt aatgcatgtt tcaatttaag
    44761 gacatctaat tgcccttctt tttcttgctg ccagatatgg atatgatcaa attcgaatat
    44821 catatcgaaa taaccgtctt tccctaccca ttgtggtcct tcttctgcag tgacaccact
    44881 tgcttctccg acagtcatga tatcgtactc ttcaaaaaca tgtttcaaat cggtcaaatg
    44941 ttcttcgatt cctgagacat tttgaaaggg tgagaaaggg ttctctgtgg cttttactga
    45001 atattcatct ttttttacat gagaaatcgc atctaaacga aatccatcta tccctttatc
    45061 caaccaccat cggatcatat tgaatagttc ttctttcaat ttctcgcttt cccaatttaa
    45121 gtctggttgt tcttttgcaa aaacatgcag ataatactgt ccagtttcat gagaatactc
    45181 ccaagcagaa ccgccgaaaa tcgatgtcca attattcggt tctttgccat ctaccccgtc
    45241 gacccaaatg taataatcgc gatacgggct ttctttagat tttttcgatt cttcaaacca
    45301 ttgatgctga tccgaactat ggttgatgac aagatccata atcactttga tccctaattc
    45361 atgtgcttct tttagcaata aatcaaaatc ttccatcgtt ccgaatctct cttctatatc
    45421 ttgatagtca cttacgtcat aaccattatc gacaaatgga gattgataga tcggattgat
    45481 ccagataaag ccgataccaa gatctttcaa ataattaagt ttttcacgga tcccattgat
    45541 gtctccttga ccatcgccat tgctatcttt gaaactagca ggatagattt gatagcctac
    45601 tgcttctttc caccattttt gttcttgtat catatcgttt cactccttta acggtccctc
    45661 ttgattataa ccgattctat tttagaagta tccttgttac cggtaactag aaacgaaaag
    45721 ctcaacgaat ctgctaagtg cgttcgctga gctttatttt atcatagata gcgggcaatc
    45781 agttgaatca tttgcttggg aaattcattc aagtcagtaa tatctacaaa acgactttca
    45841 ccgtagatcg acttgatttc ttctttgtct tggccaatag ctgcggagac aaataggatt
    45901 ccttgacgtt catattcttt caaaacagac tggatatctt cttttgcttt tttgcctgta
    45961 taatccggca acgcttttgg ctgaccgtca ctaatattaa gcaacagttt ggttgttgcg
    46021 gattgtctgt ttaatttttc tgctgctaaa cgaagtgcag caccatcacg attgttttgc
    46081 cttggtttca tagtgactaa tttttcattt aaccattgaa atccgtcttc aaattcttta
    46141 taagaaaaca aagaagtctt ttctcttgac gaacggtctg ctgtatctcc gtaaatcaac
    46201 aatgggatat cgactttctt agaaaattcg gcaatggcaa tcgctgcttt ttttgccgct
    46261 tcgatccgat catcccgtat cattgaccca gattcatcga tccgtacagc taccgctaaa
    46321 gaaggttgct catgtggcgg gttctttttg tcaaaatttc tcaaatcacc atatgctact
    46381 ttgcttgcat tgaaccgctg accttcgtat tttccttttt ggtacgtctc tgtttgttca
    46441 ttatccagta actctaaaat ttgccggcta agtgattcta ctattggcat tacttgcatg
    46501 tgtagctcac gtgcttccgg cgtttttcct tggaaagctg gtcggtgaac gatgagacct
    46561 tctttttcat gaatcgtttc cttcatgatt tgtcgcgctt ctttattcag ttgcttcttg
    46621 atttccttat catgtgcttc catgtcagaa gcagacattt cttgagaatc atctcctgtt
    46681 tgttgttctt tttgattttt tccttcgata tcgctactgc gttctttttg catttgagga
    46741 ggaatctcgt ttttttctat tgtttcttct tgtttctctt ctccctcatt tggttcttca
    46801 gcagacaacg atttcttttc atctaagcgc agaatttctt cagcattttc agtgatgttt
    46861 cgttcatttg cttcttcggc gctaatggtt ctttcttttg tatgctcaga ttgaggatga
    46921 ccccattttt cttttctcaa tatgtcctga agttccagta gcaatccact gtcagacaaa
    46981 gcttgttcaa gaattgccaa ttcatctgaa tcagtggata atttatacaa aacttttgga
    47041 taaatcgact ggagtaaatc ttgtccttgc ttataggtat ttgcccaata aaaataagaa
    47101 cgcattcctg ctacaccttt gatggcgtta gcttttgcag tttcatccaa caaacggata
    47161 atctctgcca tctttaagag aagttcttgt ttttggatca tagttttcgc catcgcacgt
    47221 tctgccatga cttctaaggc aggaagatcc attttttccg catgttgcat ccgatctctt
    47281 aaagattcat ttaatgggcg atttccttgg taatttcgat ttgtagtgat cacaatgacg
    47341 caatctggat ggcgacgaat gattcctgtc ggtaaattca acatcccatt tggttcgagc
    47401 gctgagttaa gtgccacaag aacagaggca tctcggatga cagtcggctc ttgaatctct
    47461 aataaatagc ctttttcaat cgctcgaacg atttcagaag ggtaatagct gtaatggatt
    47521 gcatctggat aatcagcttc gatcctttga actagctctg ctaatttttc tttagcagaa
    47581 aaaggatcaa tgccgtaatg gttctggatc agtgtcagta cagcttcaag tgtatctgtt
    47641 tggtaaatag cttctagtaa ttcttggtct tgttccttat tagaatctac tacaggtaat
    47701 aaggctccga aaacatctga tttgtccata tctgcaaaac aggtcacttt tgtataggga
    47761 agttgcagat cagcagatag tgctttggct aattgtgtct tccccgaccc ggcatctcct
    47821 tccaaaagta cgttactgat tttcatttca ggatcttgcc aattcccttt gatttcggag
    47881 gcgatccgcc attcttctgc acttgtccga tggcttttcg gtttcttcca gatcatttgc
    47941 ttttctagcc gtgaaaaggt tcggttttct gttagtgaga aattctccat gcttctcttc
    48001 cccttttgat catctctgtc tattaatatc ctagctcatc taaaagacgt tttaaaatac
    48061 ggaatcgttc cccaatcagt tctccgtctt tttgtagtgt atcgtaatac aaaatgatgt
    48121 cttcatcgat ctttggattt ttggtatcta cttctaccgt cattcggttc ccttgtaatc
    48181 caatgatgtc tacgactgga ttttctggat cataaaattt ttcataacga taagcatctt
    48241 ggaagtataa acttccttgc gcagctaaga tcgctaaatc taaaatacgt gtgattggta
    48301 attcttccga ctgtcgtgac catttttctc cagtatgtcg ccataccttg cctgagatat
    48361 cgacttttcc acgatcattc cactgagcaa ggcccagtga aagccctttt gcatccatat
    48421 ttaatgcatt tcttccatca actttatcat agtcttctac aacgattact ggtttatgtt
    48481 ttaaatttgt tggtatttcc attattttaa ctcctcatcc ttttattttt agtaaataag
    48541 taaattagta gtttactcat ttactaaact atatgcgaca ttatagagga ttgaagtgag
    48601 gattgcaaag aaaaagagct tcattgatag aaataaaaac accatctcgt tcttttacac
    48661 gctcattagt aacatgtaga aagtccaaga tgatgttgga atatt
//
LOCUS       DAPBCF010000018        47696 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.018, whole genome shotgun sequence.
ACCESSION   DAPBCF010000018 DAPBCF010000000
VERSION     DAPBCF010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.018"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            97..540
                     /locus_tag="RD508_001250"
     CDS             97..540
                     /locus_tag="RD508_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7735861.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(546..1730)
                     /locus_tag="RD508_001251"
     CDS             complement(546..1730)
                     /locus_tag="RD508_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HDT7735862.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            1998..2696
                     /locus_tag="RD508_001252"
     CDS             1998..2696
                     /locus_tag="RD508_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDT7735863.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2703..3380
                     /gene="nth"
                     /locus_tag="RD508_001253"
     CDS             2703..3380
                     /gene="nth"
                     /locus_tag="RD508_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDT7735864.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3506..4039)
                     /locus_tag="RD508_001254"
     CDS             complement(3506..4039)
                     /locus_tag="RD508_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735865.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4336..6717)
                     /locus_tag="RD508_001255"
     CDS             complement(4336..6717)
                     /locus_tag="RD508_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HDT7735866.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6707..7354)
                     /gene="recU"
                     /locus_tag="RD508_001256"
     CDS             complement(6707..7354)
                     /gene="recU"
                     /locus_tag="RD508_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HDT7735867.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7418..7957
                     /locus_tag="RD508_001257"
     CDS             7418..7957
                     /locus_tag="RD508_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HDT7735868.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8047..8466
                     /gene="gpsB"
                     /locus_tag="RD508_001258"
     CDS             8047..8466
                     /gene="gpsB"
                     /locus_tag="RD508_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HDT7735869.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8488..8855
                     /gene="rnpB"
                     /locus_tag="RD508_001259"
     ncRNA           8488..8855
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="RD508_001259"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9064..10230
                     /locus_tag="RD508_001260"
     CDS             9064..10230
                     /locus_tag="RD508_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HDT7735870.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10276..11772
                     /locus_tag="RD508_001261"
     CDS             10276..11772
                     /locus_tag="RD508_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HDT7735871.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11853..12536
                     /locus_tag="RD508_001262"
     CDS             11853..12536
                     /locus_tag="RD508_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7735872.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            13181..14371
                     /locus_tag="RD508_001263"
     CDS             13181..14371
                     /locus_tag="RD508_001263"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HDT7735873.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            14473..15426
                     /locus_tag="RD508_001264"
     CDS             14473..15426
                     /locus_tag="RD508_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDT7735874.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            15495..16844
                     /locus_tag="RD508_001265"
     CDS             15495..16844
                     /locus_tag="RD508_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7735875.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVIAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(17027..17350)
                     /locus_tag="RD508_001266"
     CDS             complement(17027..17350)
                     /locus_tag="RD508_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735876.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            17479..18642
                     /locus_tag="RD508_001267"
     CDS             17479..18642
                     /locus_tag="RD508_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HDT7735877.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            18712..20061
                     /locus_tag="RD508_001268"
     CDS             18712..20061
                     /locus_tag="RD508_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDT7735878.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(20106..20537)
                     /locus_tag="RD508_001269"
     CDS             complement(20106..20537)
                     /locus_tag="RD508_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7735879.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            20925..23567
                     /gene="alaS"
                     /locus_tag="RD508_001270"
     CDS             20925..23567
                     /gene="alaS"
                     /locus_tag="RD508_001270"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDT7735880.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            23767..24363
                     /locus_tag="RD508_001271"
     CDS             23767..24363
                     /locus_tag="RD508_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7735881.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            24485..25633
                     /locus_tag="RD508_001272"
     CDS             24485..25633
                     /locus_tag="RD508_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDT7735882.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(25671..26084)
                     /locus_tag="RD508_001273"
     CDS             complement(25671..26084)
                     /locus_tag="RD508_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HDT7735883.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            26163..26594
                     /locus_tag="RD508_001274"
     CDS             26163..26594
                     /locus_tag="RD508_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HDT7735884.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(26693..26926)
                     /locus_tag="RD508_001275"
     CDS             complement(26693..26926)
                     /locus_tag="RD508_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HDT7735885.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            27109..28779
                     /locus_tag="RD508_001276"
     CDS             27109..28779
                     /locus_tag="RD508_001276"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HDT7735886.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            28926..29312
                     /locus_tag="RD508_001277"
     CDS             28926..29312
                     /locus_tag="RD508_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735887.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            29299..29997
                     /locus_tag="RD508_001278"
     CDS             29299..29997
                     /locus_tag="RD508_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7735888.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            30002..30466
                     /locus_tag="RD508_001279"
     CDS             30002..30466
                     /locus_tag="RD508_001279"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDT7735889.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            30463..31374
                     /locus_tag="RD508_001280"
     CDS             30463..31374
                     /locus_tag="RD508_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDT7735890.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            31609..32148
                     /gene="pyrR"
                     /locus_tag="RD508_001281"
     CDS             31609..32148
                     /gene="pyrR"
                     /locus_tag="RD508_001281"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HDT7735891.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            32162..33445
                     /locus_tag="RD508_001282"
     CDS             32162..33445
                     /locus_tag="RD508_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDT7735892.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            33458..34384
                     /locus_tag="RD508_001283"
     CDS             33458..34384
                     /locus_tag="RD508_001283"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HDT7735893.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            34403..35683
                     /locus_tag="RD508_001284"
     CDS             34403..35683
                     /locus_tag="RD508_001284"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDT7735894.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            35688..36764
                     /gene="carA"
                     /locus_tag="RD508_001285"
     CDS             35688..36764
                     /gene="carA"
                     /locus_tag="RD508_001285"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDT7735895.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            36769..39954
                     /gene="carB"
                     /locus_tag="RD508_001286"
     CDS             36769..39954
                     /gene="carB"
                     /locus_tag="RD508_001286"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDT7735896.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            40008..40784
                     /locus_tag="RD508_001287"
     CDS             40008..40784
                     /locus_tag="RD508_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HDT7735897.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            40781..41713
                     /locus_tag="RD508_001288"
     CDS             40781..41713
                     /locus_tag="RD508_001288"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDT7735898.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            41710..42426
                     /gene="pyrF"
                     /locus_tag="RD508_001289"
     CDS             41710..42426
                     /gene="pyrF"
                     /locus_tag="RD508_001289"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDT7735899.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            42433..43062
                     /locus_tag="RD508_001290"
     CDS             42433..43062
                     /locus_tag="RD508_001290"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDT7735900.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            43050..43364
                     /locus_tag="RD508_001291"
     CDS             43050..43364
                     /locus_tag="RD508_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735901.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            43402..44043
                     /locus_tag="RD508_001292"
     CDS             43402..44043
                     /locus_tag="RD508_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7735902.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            44086..44778
                     /locus_tag="RD508_001293"
     CDS             44086..44778
                     /locus_tag="RD508_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HDT7735903.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            44775..45677
                     /locus_tag="RD508_001294"
     CDS             44775..45677
                     /locus_tag="RD508_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7735904.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(45835..47541)
                     /gene="efbA"
                     /locus_tag="RD508_001295"
     CDS             complement(45835..47541)
                     /gene="efbA"
                     /locus_tag="RD508_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HDT7735905.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        15520 a         8350 c        10270 g        13556 t
ORIGIN      
        1 tcttggtttc agattgggtt ttcctacaaa atatttttat ctttgttgaa taggaaacaa
       61 aaaaacaata taatgaaaga aaaagaaggt gtagaaatgg ataaaagaca actgctaata
      121 gaagaatatc tggatttagc taatgagatt attcatcgta ataaaccaga aatggaaaaa
      181 gaatttgcag gatttactct aaatgaacta gaagtgattg aacatatcgg gaaaatccct
      241 gatcctaacg tgacaaaatt agcgaatgct agttacatga ctagaggagc catcagtaag
      301 ctaacaaaaa aactgatagc tagagggatc ataaacactt atcaaagcga agagaataaa
      361 aaagaaatct attttcaatt gacgccaatc ggacaaaaaa taaggaatag acacgagcaa
      421 ctccatcaaa aatgggtaca gcgagatgct actgtatttg aaaatatgtc aaaagaagaa
      481 tttgacacag tatttcgttt tatcggtcga tacagagaat ttatacgaag tagcaaatga
      541 agctactatt ttttattgta gtgataatag gcaaaaatca taagcaaaaa tccgaatacc
      601 gtcggaagaa atggtgctgc agcataaagc tgtcctgcga ttagcgggcc gatgacgcgc
      661 gatagagatt gtatactttg ggtaccgccc attacaagac cttgctggtt atctgagaca
      721 gaattggata gttggccatt gaatacagga gtaaaaatag aatcaccgaa accataacag
      781 ataatcccaa ataaaaacaa aatcggcagt agaagaattc cagataatgt gatgaataga
      841 taggcgagga tttcactgaa catccctatt cttgtgatct gctgttctga aaattttttg
      901 agcaatcgag gcataatgaa caattgcgag acagtatcca agattccaat caaagagaag
      961 cttaaaccaa ccaacccagc cttccactga aaggcgtcaa tcgaaaattg agaaaagata
     1021 gattgaagag agccagctgc caaccaaaca gcaaaacctg ctgtcaataa aggaataacg
     1081 gatgaaatct tgaataattg ttgtaattgg tgaaaaggtc ttacatggga gaaacttaaa
     1141 tctactgaac gtttttttat tggaaggctt tctagcataa atgtgtagcc ataaacggca
     1201 tttaagaaag taaagagtgc tccaataaat ataggaacag aattccccaa ctcagctaat
     1261 agacccccta taataggacc cagcgttgtt cctataccga ctaaagcacc catccatcca
     1321 aaaactttgg ttctttcatt aggttccgtg atgtcggcaa agtaagcata taaggtggag
     1381 atttctcctg ccgtcaatcc ttcaatgata cgaccaagga acaacatcca tatcgaattt
     1441 cctaaaccaa aaagcaaata tccgatactt gatcctaata aactgataat aaggatcgga
     1501 tgacgcccaa aatgatcact taagctaccg agaatggggg cagataagaa ggcagctaga
     1561 gcataaacag acatgagcaa agtgatatag aaagcttgct gatgtatgga gtgagaataa
     1621 ggcagcgtta aaaacggaag tacaggactg acgatagtaa atcctaatcc agtgaataag
     1681 acagagacgt atccaaaaac tttagaatgt ttatttgtga aactgtacat gtaaaaactc
     1741 ctttatgcaa taatgttaac ttggaaacaa aaatagtgta tagtaatttt gtttccttgt
     1801 caacattcta aggaacagcg aaatctactt aatttattta ttccgaaaag tgaagatacg
     1861 catcaaaaac atgaacaaac aaaaatcaag tagacgacat tgtaaatctg accgatcagt
     1921 gaagtaaata gaaaagaaac ctgttcttgc ttcccatgtt ttttttacgt atactgtgat
     1981 tgagcggagg agaaatcatg ttgaatttag aaaattactt aagcgctgga caaacagtca
     2041 tatctaatct tttacttaaa aattatcata ggatcggtct acaatctgaa gaatttttat
     2101 ttgttctaca gttgcatatg gcacagcttg aaggagatac tttccctgat ttgcagatga
     2161 ttgctatgga tatgggaatc aaacaagatc agatttttca aatactggat cgtctcgtaa
     2221 caaatggatt tatcaagata gaaacgacga ttgtcaacgg taaaaaagca gatcgatata
     2281 atctttaccc catctatgat ctattaggtg agtatttaaa aacacaagaa aaaaaatacg
     2341 aagaaaaaac acaagaaaaa gaaatccagt cagtgtatca attatttgaa caagaatttg
     2401 gacgcccgct ttcttcgatc gagttccagc ggatcggaca atggctagaa gaagaccatt
     2461 atcagccgga aattttgaag ctagcactgc gggaagccgt attaaatcag gcttatagtt
     2521 ttaattacgt tgaccgcatt ttgctatcgt gggaaagaaa aaatctacgt acaaaacaac
     2581 aagtggaaga agaccaaaaa cgaagaaaac agcagcttct tcaaagagaa gtagaacagt
     2641 cagctcaaca agaagaattg ccgaaagtct cactgaaaaa ttggttggag gagtagcgga
     2701 atatgttaag caaacaaaaa acaatggaag ctctagaaac gatgtatgga atgtttcccg
     2761 aagcacatgg agaactcaag cacaataatc catttgagtt attgattgca gtgatcttaa
     2821 gtgcccaggc gacagatgta tcagtgaata aagcaacgcc agatttgttt gcctcttttc
     2881 cgacacccga tgcgttagca gaagcttcaa tcgatgaaat cattcttaaa ataaaaacga
     2941 ttggtttgta tcgaaataaa gcaaaaaaca tcaaagcgtg tgcacagcag ctgattgaac
     3001 gtttcgatgg gcaagtgcca acgtcaagag aagaattgat gtctcttcct ggtgtaggca
     3061 gaaagacagc aaatgtcgta ttgggggatg cattcgggat accagcaatc gcagtagata
     3121 cccacgtgga acgtgtctca aaacgcctga ggatctgcaa actagatgct acggtcatgg
     3181 aagtagaaga aacactgatg cggaaagtac cacaagaatt atgggtaaag acacatcata
     3241 cactgatttt ttttggtaga tatcattgca cggcaagaaa tcccaagtgc gaggtatgtc
     3301 ctttgctatc aatatgtcaa gatgggaaaa atcggatgcg tctaaaagaa aaggcgctaa
     3361 aaaagaaacc acgcctgtag acgtggtttc tttaattgca aataaatgta tgaattatct
     3421 tgttattatg gagaaaagct gtttcgttta tcttttttgc atgaaaaagt aaatgtacat
     3481 actcagtagc taggatggta acttattaca atttattgcg ataaaaataa aagttgttat
     3541 ttttattggg aaaatacccg atgtagaaaa taatgccttc caatatacct ataaaataag
     3601 tccagtattc caaaggatta tataaataag tgacgtatct atctaaaggt gtaataaaaa
     3661 tgataagtga taataaaaaa ataccattta taactaaaca taaactaatg gatttgggcg
     3721 gtttcaggct catcagaaaa atatagattc tggtgaacaa caaccataaa aaagtgagaa
     3781 tcattgcatg agagcttctt tccataaatt ttcctttaag agtagtgctt aaaagtacag
     3841 aaaaaataat aaatgcaagg ataggagcaa ttaaagtaaa tttatttaat aataaacaaa
     3901 atttttcagc ttttttattc ttggaataac gaggtattgt tttcgataaa aaaagatggt
     3961 gcagacaaat tatgataatt aagcatacta tcagataact caaaatgaag ccttctttca
     4021 aaaaattatt caaaaccata tattgtattt tttatttgat aataacaatg ggattattaa
     4081 gaagtggcac taaataaaag actagtgtgt atttagccga tttaattata aacaagtaaa
     4141 tggataaagt atatgtaatg ataaaagaaa aatggatttt ctaattttta agctaaatgt
     4201 tagatcacac atgtatatgc tggatagtct tataaaaaat catgtaatac agcttggtac
     4261 atgattttta tttgtagctg ttttttacat agacacaaaa aagaaaccac gcttgtagac
     4321 gtggtttctt ttttactatc tgtttccaga agctgaggtg ctgctggatg gtgtatggtc
     4381 atttgcagca tccgctccgc tagttgctgg ctcactggaa gaagcaggag gagcagatga
     4441 agacggtgtc gagctttctt cggatgaaga agaaggaacc gttgttgaag acgctggctc
     4501 gcttgtttct gctgtcgtgc tttcttttga ggactcagca gttgattcgc tttgactagt
     4561 agagctagag ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct ggacatagct
     4621 ggaagatgga atagttgttg atggtgtaat tgcattcgat ctagctgtat attgatcttt
     4681 gtagtacagt tcaccgccca cacgaattaa tccgcttggc atctcccagt ctgtatttgt
     4741 cacgttagct gaaacatact gcataagctc gcgataaaca tcagaggcta cgtgtgacga
     4801 ttctgaagtg acaggtgtca tttttttatt gtaacctgtc cacacggaaa tcgaataatt
     4861 tggcgtatag cccgcaaata ggatatctgg atacacccca gaagaaatac caagttttgc
     4921 atactcgtca tctgtgtaat tggatgttcc ggtcttaccg gcttgatata acccagcgat
     4981 ttgcgcattc gtaccagttc cttcagtgat cgtatctttt aaaatgtctg tgatcatata
     5041 agctgtttct ggagacatgg ctgtttttcc atctggctca taagtttctt ctgttccgtc
     5101 ttggaagacg attttattaa catattgagg tttgtaataa gtccctccat tggcgaaagc
     5161 cgcataggct gctgccattt ttaaggaaga agctccgtat tttgtcccat cttgttcttc
     5221 cgtattacta gagatcgcat tcgattgatg gatcgtactg tattcgatcc caagattttt
     5281 taagaaagaa gccactttat ctgaaccgac ttcattgaat aatttgactg ctggaacatt
     5341 acgggataag taaagtgctt ggcgtaaagt aatggtgccc atatattgat tatcccagtt
     5401 tcctacagga gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag tttttccagt
     5461 agaatatttc aaatattcaa aagctggtcc gtaatctgtg acaggtttca tcgtagaacc
     5521 aaaatcacgg gaagtattca ctgctaagtt gttgcctaaa gttacgtctt ctgcgatgtg
     5581 acgtccgcca atctgggctt ttactttccc ggtattggtg tcgataaggg tggaggcaac
     5641 ttgcatctcg tcgtctgggt aagagacata ctgatccgtg ttgacgatat catatagttt
     5701 cttttgggcg tccagatcca aattcgtata aatctctaaa ccgtctgtgt agacattctt
     5761 atctgttttt tcttgtactt cattgatgac ttctttgaca taattatcga cgatcttagt
     5821 attgtcatcg gattgagtta gttcttgcag accatccgtt accggtacat taacagcttg
     5881 atcatattct gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa cagtatctcg
     5941 tcttttcttc gcctgatctg gataaacata aggatcatag gcggaagggg cttgaggcat
     6001 cccagcaagc aatgctgttt gcggtaaaga aagttctgat aatttcttac caaagtacat
     6061 ctcagaagct gtctccatcc cgtacaagcc gtttgacata tacactttat ttacgtagta
     6121 ggtcaagatc tcttgtttcg attttttttg ttccaatctt acagccatcc acgcttcttg
     6181 ggccttgcgt ttcagagtct gatcctcggc actggtggag aagaaggaaa gtttgatcaa
     6241 ttgctgtgtc aaagtacttc cgccttgcag tccgccagag gtaaagttag agagggcaga
     6301 accgatgatc cgaatagggt caaccccgat gtgtttataa aaacggcgat cttctaccga
     6361 cacgatcgca tcttctaatg ttttcggtaa ttcattcgca gaaatttttt cacgcttttc
     6421 tgcgcctaaa tcttcgaata gttcgccatc ttgtgtatat agtttggaag atacggtagc
     6481 gtctaatttt ttatccgtca attcgggcgc atcttttgcg taataccaga aaagtcctac
     6541 acctgctaaa aagaggatac agaaaaatga gagtattcct aaaaggatct tgataaataa
     6601 tcctttttta tgtgttccag aggactttcc agaacctttg ccagaattct tcttcacact
     6661 ctttttagga gtaggctgtt tctgtcgtct agagcttcta gtttgttcat ttgccattct
     6721 tgctttctcc ttcaatagat aatgttgata aatagaagtc aaccgcgtcc aaataaggaa
     6781 tccgcggaga aataccagtt ttgatctcta ttcctagttc ttcgatcaaa gataaaggta
     6841 gtgatttgcg tcctttttcc ttttgggcgt cccagtaagc aatcaaatga acactattca
     6901 aataaaaaca gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc ccattttgtt
     6961 cgaggcatgc tttcatatgt tcgatttgat gggcatggaa gtttttaaag ggaaaagatg
     7021 ttttgttctt ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag acgccattat
     7081 agtctgtagt tgaggcttgg gtaaagtagg cttccttgat cacagcagca cttctcttag
     7141 gatagtctac tttcacgatt tggatagggg taggcttttt atggataacc gccaacccgc
     7201 gggaaagata atatttatta ctttcattga ttgcttcttc aaagcgcatc ccccgattgc
     7261 cgaattcagt gatctgattt cttttttctt gaattttttc gacgggagag gcattcttat
     7321 aataaggttg gccatttgga tagcgcaata ccatctttaa tcacactcct aggccacatt
     7381 atagcaaaaa agcggataga aagaaaagga atctgagatg gataagtcaa aagtaatcta
     7441 tgtgtctggg tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc ctaaaatcca
     7501 agttgttaaa aatgttttaa aaaaagaact ccatcagtta gcagaagaag ggctggaatg
     7561 ggtacttgtc agtgggaatt tgggcgtcga actatgggct gtgcaaatag tagcggaatt
     7621 gaaagaagaa tatccggaac tatctcttgg tattttgtat cctttttctg attttggtaa
     7681 taactggaat gaagggaacc aagaaaaaaa acaattagca gaacaattag cagattatgt
     7741 cgaagctgtt agccatcaac cctaccaatc acctagtcag ctaaagaatc acactcgttt
     7801 tatacttgag catacagtgg gctgtctgct gatctatgat gaagaattcc ctggaaaaac
     7861 gaagtatttt tttgaagatg cacagaatta ccaagcagat catccctacg aaattcggct
     7921 gatcagtatg gacgatcttc aaaattttag tgaataatcg atattgtgtt tgatttatca
     7981 acttttttcc tatacaatga aaaaggtaga aatgttatta cgtaaatgaa aactagaggt
     8041 gtaaatatgg cgaatttggt ttatagtcct aaagacattt tacaacaaga attcaaaaca
     8101 aaaatgcgcg gctatgatcc cgttgaagtt gatgaattct tagacaatat catcaaagat
     8161 tatgaaactt acagcaaaga actccttgct ttacaagaag aaaacgatcg attgagtgca
     8221 aaagtagctc aattatctaa aactcaagga gcagctcaaa cacgcgtgca acaaacagag
     8281 gcaccaaaga gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc aaatcttgaa
     8341 cgtgaagtat ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc agcacaacct
     8401 aatccaaata actacacaaa tgcagacaca agcttagatg ataatgaaaa aacacgtcaa
     8461 ttttaatttt tgattaatga atttgcggtt ttcgggtaat cgcggtctga cttgatcagg
     8521 ctgaggaaag tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc ttagcgaaac
     8581 cataagctaa ggtactcttt ggagtaacgg caggaaaaca agctaaggct tcggctatgc
     8641 ttaagtatcc ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat ccggtggaac
     8701 gcggtaaacc cctcgagcga gcaacccaaa caatggtagg ggcgcttttt gtctggaaga
     8761 agaacaggac aaaaaggcag tataactgca gatagatggt taccgctttg ttttttctcc
     8821 ctggaaaagc aaagtacaga acatggctta tagaaaaccg caaacatcag ggaattaggt
     8881 cgtgacaaaa gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta tttttcaata
     8941 cttcagatga atcgttctta ttacaaaaca aacttttgta tcaccggtta ttcggaattt
     9001 gagtaaaagt gtggggtagg actgatgtcc cacctccttt ttttataaat aaggagattg
     9061 tgtatggaaa aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg gctagaagca
     9121 ctggttggta aagaattaag agatcttgga atcgaatgcc aagttgagaa cggacgtgca
     9181 cgttttgaag gaacaatgga aacgatcgct acagctaatt tatggttacg tacagcagat
     9241 cgagtaaaaa tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt gtttgaaaac
     9301 gtaaaagcat tgccttggga agattttctt ccactagatg cagcttttcc tgtagctgga
     9361 aaatcgatca agtcgaaact atatagcaca cctgattgcc aagcgatcac aaaaaaagca
     9421 atcgttgaac gtctccgtac ctattatcac cgtccagctt ctgtaccact gacggaaact
     9481 ggcgcacatt ttcagttgga agtagctttg ctgaaagacc atgtgatggt aactctggat
     9541 acgacaggac caagtttatt caaacgtggt tatcgcttag aaaaaggtgg agcaccattg
     9601 aaagaaaaca tggcagcagc acttattatg ttgacaaatt ggcgaaaaga ccgtccattt
     9661 tatgatcctg tatgtggttc aggtacgctt tgtattgaag cagccttaat aggccataat
     9721 atcgcaccag gattcaatcg tgagtttgct tgcgaatctt gggattggtt cagtcaagaa
     9781 atcatggaaa atgttcgatc agcagccgaa gaaaaagcag attatgatat tgaattagat
     9841 attactggtt cagatatcaa tggacggatg attgaaattg ccaaagccaa tgcagaagaa
     9901 atcggattag gctcttcgat tacctttaag caacaagcag tcaaagactt caaaacggat
     9961 aaagaatacg gggtcatcgt ggctaatccg ccttacggag aacgtctagg agaagaagaa
    10021 actgttcgga aattatataa agaaatgggc gatgtattcc gtccattaaa aacatggagt
    10081 aaatatatct tgactagcga cttagcgttt gaggaatttt acggacaaaa agcaaccaaa
    10141 aaaagaaaat tgtacaatgg tgcattgcgt acggatctat tccagtattg gggaactcgt
    10201 ccgcctagaa aaaaagagaa agacgaataa tcttactaat tgattcattc aattggatgt
    10261 ttggaggaat agggaatgaa agaaaaagag tttttacaag aagtaaaaga aatcaatctt
    10321 ctacaacaag ctttaggaat cctcgattgg gatacacaaa caggtatgcc tgaaaaagct
    10381 agtgcatacc gaagtgaagt agacagctat ctttacagca tttatttttc aaaaaaaatc
    10441 ggtccaaaaa tcaaagaagc cattcgctat ttttctgaac atccggaaga attgtcggaa
    10501 gttggaactg ccgtttttgc caaagtaaaa gaagagtatg atttggaaca tcgcgtaccg
    10561 gaagatctta tgagaaaata tacagctgcc gtttcttcag cacacggaca atggcaaaaa
    10621 gctagagaaa cacaacaatt ttctgatttt caacacgcat tgaatcaaaa tattgaatta
    10681 acaaaacagt tgatacctta ctggagaaaa gatgaaaaga cgaattatga tgttttgctg
    10741 aatcaatacg aacccgggat gactgtcgaa atccttgata aggtatttga tcagcttaaa
    10801 gaaggaattc tttcgatccg ccgtacgctc caagaaaaag ggactgaacc tgaaacagac
    10861 tttttaaatc ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa agtaatcgaa
    10921 caacttggtt atgattttag tcgtggtcgt ttagatgaca ctgtccaccc atttatgact
    10981 ggaattaatc cgaatgatgc acgaatcacg acacgatgga acgaaacaga tttcaaaatg
    11041 gctgtttttg gagtgatcca cgaggctggt catggtatgt atgaacaaga catcgatgat
    11101 aaatatgcgt atacaccggt ttatgaaggt acatcaatgg gtatccatga atcacaatcg
    11161 ttgtttaacg agatcattat tggaagtagt cgcagcttct ggaaaaagca atatcctttc
    11221 tttcaagaat gtgcagaagg aacattcgat gatattcctt ttgacaaatt ttatcgttca
    11281 ttgaaccata caaaatcaag tttggttcgt atcgaggcag acagtttgac ttaccctctc
    11341 catatcatca ttcgttatga aatcgaaaaa atgattttca atgaaggggt agatgttgct
    11401 gaactacctg aaatatggaa tcaaaaatat gaagagtatc tgggaatacg accaacaaat
    11461 gatgtggaag gcatcctaca agacgttcat tggtcaggtg caagctttgg ttattttccc
    11521 tcttatgcat tagggtacat gtatgcggca caattacttc attctttgca gcaagaaata
    11581 gatgtggaaa atgttctagc gtcagacgat tattctccaa tcaaaaactg gatgtcagag
    11641 catatccatc aatatggtgc atctagaaaa ccaaatcaat taatcatgga tgcaacacat
    11701 gaaccgctta atccgcaata cctgatcgac tatatgaaag acctgtattt taatgtatat
    11761 caggtaaaat aaaatacaat ttacaaagat agctgaaatt catctaatct atagatgttt
    11821 tcagctattt acttaagaaa gaagtggaac gaatggataa attacaagtg atcgctgatt
    11881 atagtatgga ccaattagcg catgatcaaa caggacatgg gagcgatcat accaaaagag
    11941 ttgtcaagtt agctgaaaaa attttggaga cggaaccgca ggcagaccgc tttgtgacgc
    12001 ttgcagcagc ttacctacat gatacgattg atgataaagt cgttaaaaat gagaacgagg
    12061 caaagcaaca gcttcgtgta ttccttcgct ctttgccaat agtagaggaa cagatctcga
    12121 tgattttttc cattatcgaa aatatgtcct tttctaaaaa tctctctgaa gcggccgaac
    12181 tatctctgga aggtaagatc gttcaagacg ctgatcgtat cgaagcatta ggagcaatcg
    12241 gcattttgcg tactgcttat ttcggcggtg gacatgggca cccgattttt gatcctgaac
    12301 tgtatccgca aacattcaag gacaaagaaa attaccgaaa aggcacgaca gtgatcaatc
    12361 atttttatga aaaactgttc ttgctgtctg ataaaatgaa tactgattac ggatatgaag
    12421 aagccaaacg aagagaaacc ttcatgcgtg aattcttaga agaatttttt ctggaatggt
    12481 ctattgacga tgaaaatttt actccagaca attggatcaa aaataacaaa aaatgatgga
    12541 ggttgtgaca gaagtggtca gctccaagat atttcggatc attttccgta aaagttactt
    12601 ctggaacact gtttaccaag aggtcgtgag cctgccgttc agctccgagt cacaaggaac
    12661 aatttcaaaa aatagcttct cgtgtttgat gaatattgta acttgtgatt cggaattggc
    12721 aggagaacac cgtttattcg gaagaatagg actgtgacaa gacttttgtc acagtccttt
    12781 tttcgaattc aacaagtaaa acttttaaga aatattcaga gagtaaaatt aaaaattgct
    12841 gataaacgaa gatggaaatt ttatgtattt ttattggtct atgcaataaa taaattaaat
    12901 attcagaata caattgattt taacgaaagg gcttctatca atggttgtgt tgtatttatc
    12961 tgcccaggta gagtaaaata gatcattatc taaaaggtaa ttgttcatac tatataagtc
    13021 atttgaaagt aaaaagatac tgtaaataaa aaatgtggtt aaataattct cataatcagt
    13081 gtaagcgtta tcaaaaatat agcatacttg ctttgtagat gaatgacacg atatatgttt
    13141 ggtatgttct gcaagacaga tgaatatgga ggtggagaca atgtcttcca aagaactaac
    13201 aatgtattta gagaaagaat tggatcaact gaaagaaaag gggttataca atacgatcga
    13261 catactagaa agtgaaaatg gtgcttgtat catcgtagac ggaaaaaaga tgatcaatct
    13321 agcatccaac aattatcttg gatttgccaa tcgcgaagaa ttgaaaaaag catgtattga
    13381 agcaaccgaa acttatggtg taggagcagg agcagtccga acgatcaatg gttcgctgaa
    13441 aatccatcag caattagaag aaaaaatcgc agaattcaaa gggacagaag cagcaatcgc
    13501 ctttcaatct ggattcaact gcaatatggg cgctatctct gcagtaatga caaaagaaga
    13561 tgctatctta tcggatgaat taaaccatgc atctattatt gacggttgcc gcttatccgg
    13621 agcaaaaatc atccgaatta aacatcaaga tatgaaagac cttgagaaaa aagcaaagga
    13681 agcgatagaa agtaagaaat ataaaaaaat catgtatatc acagatggtg ttttctccat
    13741 ggatggagac attgcacgat tgccggaaat tattccgatt gttgaaaaat atggactgat
    13801 cacctacgtc gatgatgcgc acggctcagg cgtaactgga aaaggtgcag gaaccgtcaa
    13861 gcattttgga ttaagcgaca aaatcgatat gcaaatgggc acgttatcga aagctatagg
    13921 tgttgttggg ggttatgtag ctggatcgaa aacactaatc gactggttga aagctagaag
    13981 tcggccattc ctattttcta cttcgctaac tccaggtgca gctgcagctg cattggcttc
    14041 gattactttg atgcaagaac atccggaact tgtcgaaaaa gtttgggaaa atgctaatta
    14101 ttttaaagaa gaattgaaaa aagtaggcta taacatcggt atgtctgaaa cacctattac
    14161 tccagtcatt ttgggagacg aaaaagtgac tcagactttc tctaagaagc tgatcgaaca
    14221 tgggatttat gctaaaccaa tcgtttatcc aactgtgcct cttgggacag gcaggatcag
    14281 aaatatgccg actgcggaac atacgaggga aatgcttgat gaagcagtag cagtttatca
    14341 aaaaatagga aaagaaatgg aaattattta actaaattta gttttttcgt ctatttaaaa
    14401 ttagagaaca tgttcacgca tatattgtta atcatctgaa gatagtagta aaaaagatca
    14461 gggaggatca tcatgaaaaa agtattggtg acaggatgtt taggacaaat tggttcagag
    14521 ttgatcacac ggctacgtca agaactaggc agtgaaaatg tcattgcgac agatatacgc
    14581 atgcctgaag tcattgagaa aaacgatatc tttgagatcc tagatgtaat ggattacgaa
    14641 aaaatgcgca gcatagcaga acaatatcaa gtggacacat tgattcattt ggctgctctt
    14701 ttgtcagctg ttgcagaagc aaaaccacaa ttagcctgga atttgaacgt gactgggctg
    14761 gtcaatgcat tggaagtcgc tagagaattc cagctgaaat tttttacgcc aagttcaatc
    14821 ggcgcgtttg gtccaaatac tccaaaagat cataccccac aagatactct tcagcgtcct
    14881 acaaccatgt atggggtaac gaaggtagct ggagaactac tatgtgatta ttattatgtg
    14941 aaatatggcg tagatactcg tggtgtccgt ttccctggat tgatttctta tgcaaccttg
    15001 ccaggaggcg gtacgacaga ctacgcagtc gatatttatt attcagcaat caaagaagga
    15061 aagtacacta gtttcattga tcaaggtaca tcaatggata tgatgtatat gccagatgcg
    15121 atcgatgcca ttataaaact catgaatgca gatcctgatc gattggttca tcgaaatgcc
    15181 ttcaatatat cggcgatgtc ttttgacccg gaagagatca aagcatctat tcaaaaaatc
    15241 ataccagatt ttgaaatgga ttatgatgtg gatcctgtac gtcagtcaat agcagaatct
    15301 tggccaaatt cactagatgt ttcttgtgcg caagaggaat ggggcttttc gccgaaatac
    15361 gacttagatg tgatgacaaa ggatatgttg gaaaaactga aagaaaaatt ggtagagacg
    15421 gtataaaaca agaaccacat ccaaaaagtt ttttatactt ttgggattgg ctatggtatg
    15481 aaaggggaca agggatggaa gaatatcaag ccacgccagt aaaagaagta aaaatagaaa
    15541 atgaattaaa acgtacgatg ggatttttta ctgctttatc gactgttatg ggcacagtga
    15601 tcggtgcagg ggtatttttt aaagccgcaa gcgtagcaga agttacagga tccgccagtt
    15661 tgcatatgtt ttcttggttt ctcggtggta tgatttctgt ctgtgcagga ctaacaggag
    15721 ctgaactggc agctgctatt ccagaaacag gagggatgat taaatatatc gaacggattt
    15781 acggaaatac agcagctttt ttattgggct gggcgcaagt cgtgatttat tttccagcaa
    15841 atgtagcagc cttgtcgatc attttcggta cacagttcgt caatctattt ggtctttccc
    15901 agtcaatgat tgttcccgta gctgttacag ctgctgtatc gatcctgttg atcaattttt
    15961 taggttctaa agctggaggg gcttttcagt cgattacgct tgtctgcaag cttattcctt
    16021 tgtttgtgat cgtcattttc ggtttgttcc gacaagaagg agtagacttc caactgtttc
    16081 cgatccaagc aggagaaaat ctttcatttt tctcagcctt gggagcgggc ttgctagcaa
    16141 cgatgttcgc atacgacggt tggatacacg taggaaatat ttcgggagaa ttgaaaaagc
    16201 cggcgaaaga tttgccaaaa gcaatttctt taggaatcat cggaatcatg atcgtttatt
    16261 tattagtaaa tgcggtgttc ttaagaaccg catctatcga cggagtcgca ggaaacagca
    16321 atgcggcaag tgacgttgca aaaatgattt ttggcggctt cggtggaaga ctggtcacag
    16381 ttggtatctt gatttctgtt tatggaacca tcaatggcta tacccttact ggaatgcgtc
    16441 tcccttatgt tattgcaaaa gaaaacaacc tgccttttag caagctcttt gctaaacttc
    16501 atgataaaac taaagttcct gtagccgcag gtatcttaga gctagtcatc gctattggca
    16561 tgatgatgat cggtggtttt gatacactaa cggatatgct gatctttgtc atttggattt
    16621 tttatacgat ggtctttgtt ggtgtcattc ttcttcgtaa aaaagaacct gatttgtttc
    16681 gaccatacaa agttccaatg tatccgttta ttccactagt agcaatcatt ggagggactt
    16741 ttatcgtatc aagcacgctt atcactcaga cctttttagc ttcgatgggg atagtattga
    16801 cacttgctgg tatcccgatt tatctctatt taaaacgtag atagctaaaa cattcgaatt
    16861 ttattagaac tgcacttctc tgccaaacaa aatattttat ttaaatgagg agtacgtgga
    16921 agaaatgtca aaagtactcg ttaattttga tcacgtaaat gtcgttttgt ctacgatgaa
    16981 atagcaaagt aaaagacaga aatcgggctc aaccgatttc tgtcttttac tttgatttgc
    17041 gtaactgaac tattcggcgt acgccgcgat aaatatttaa taaaaccaag caaccagaaa
    17101 tgaaaatggg aagccaaatc agatagacag ggtagccaag cactttagac aaagcatgtg
    17161 gagtcatttt atccatttca agaagtgctt gctgccaagt ctgaagattg aagactagca
    17221 tgaaacccga aataatcagg agaataaatc ctaaataatg aattgtagtt ctttttctta
    17281 cataagcgat cgtagcataa aggaacagta aaaaaatagg tacgccaaaa acaaagtaca
    17341 tattcagcat ctcgacaccc cctttgtgtt tatcttactt tactttgaaa gaaatgagaa
    17401 ataatagcct cgttacttgc ttgaaacagc aaaggactgc taagataaga gagatacaaa
    17461 gaatcaagga ggagtcatat ggcaagttat atcgaaccga ttcgttttgc gctgattgtt
    17521 tttccatttt tagccttagc gatctcatct gtttttttta tttatgaata tcgaaagtat
    17581 ggaacatttc tagtaacaag ggcagttatt ttgtattctt tcgtttttta tttattgtgt
    17641 gcgtattttt tggtgatctt accacttccg gcaaaggaga cggttgccca aatgacaggg
    17701 ccaaagatgg agctgcattt atttgcttca tggcaacatt tcagagacaa cacggtattg
    17761 gtcttgtctg aacctagtac ctacctgccg gcaatgaagc agagtgtatt tttggaacca
    17821 gcttttaatg ttttattact cataccattt ggcatttatt taagatatta tttccggctt
    17881 tcttttatga aaacgatgat tgctagtttc tgcctttctc tattttttga attgacgcag
    17941 ctaagtggac tttattttat ctacccaaga ccataccgct tatttgatgt gaatgattta
    18001 gtgacaaata cattgggtgg aatcattggt tttgtcgtta cgccgttatt tacatttatg
    18061 cttcctacaa gaagacgaat ggatgaactt tcttatgaaa aaggaaagac tgtctcattg
    18121 actcgacgct tggtcgctta tttgatcgac tggacatttt tatctcttat taatttggta
    18181 gcggcgattt tctttaaaat tgcgttcgat tcaggggcag ttacttctca tatctggtgg
    18241 cttttattag aagtaggggt atactttatg attgtaccgt ttataaccaa tggatggaca
    18301 cttggcaaaa aaattgtgcg tatccgtttg gtggaagaag accgcgaacg aatttcttta
    18361 aaagcattga tgatccgcta cgggtatctg tactttcttt tttatggttt aagctggttg
    18421 gggcagttgc ttcagcaaat catgaattcg acaacgaata cggtgttgca gatgagtgca
    18481 gtattcattt ctctcggtgt cttgttacta caaggtattt ttattttaaa tatcttgcta
    18541 tcatttttga gaaaaaaacg gattctgttt tatgaaaaag ctagtcacac atatactgtt
    18601 agcacgattg gccaaacaaa ggatgatgat tctcgaaatt agctgagcaa aaacgctttg
    18661 tctgtgttat aatgccaaag tcgtgataat ttaaagagaa gaggtgcacg aatgaataat
    18721 tttgatatat tccgcttcaa accgtttatc aatgaagcgt taaccgcaaa gggcttcaaa
    18781 cagcccacag aggtccagga acgtttgatt cctttaattg caaaaggaaa aaatatcatt
    18841 gggcaatctc aaactggtac aggaaaaaca catacgtttt tgttgccttt gtttgaaaaa
    18901 atcaatgcag aaaaagagga agtacaagtt gttattacag ctccaagtag ggaactagct
    18961 gcacagatct atgaagcagc tacacaaatc gctaaatttt ctacaccgga gatccgtgtc
    19021 tcgaattttg tcggcggtac agacaaacag cgtcaattaa atcgtctgca tcaccaacag
    19081 ccacaggttg tagtaggcac gcctggtaga atattagaca tgatgaatga acaagcgctg
    19141 aagattcaca ccgcatttgc atttgttgtc gatgaagcgg atatgacatt ggatatgggt
    19201 tttttaaatg aagtagacca aattgcaagt cgattaccag aaaagctgca gtttttagtt
    19261 ttttctgcca ctattccaga aaaacttcgt ccattcttac gaaaatacat ggaaaatcca
    19321 atcattgaag aaatcaaacc aaaagcagtt atttctgaag acattgaaaa ttggctgatt
    19381 tcaacaaaag gtaaagatga gaatcaaatg atttatcaac tgctgacaat tggtcatcct
    19441 tatttagcaa tcgtatttgc caatacaaaa cagcatgtgg atgaaattgc cgattacttg
    19501 aaaaaccaag gcttgaaagt agcaaagatt catggagaca tcaccccaag agagagaaaa
    19561 cgagtgatgc gacaagtaca gaatctggag tatcaatatg ttgtagcgac tgatttagct
    19621 gctagaggga tcgatatcga aggtgtctct catgttatta atgcagaaat tccagaagat
    19681 ctagacttct ttatccatcg tgtcggacgt actggacgta atggcttaaa aggaacggcc
    19741 attacgttat attcgccaaa tgatgagcaa gccattgatg cgatagaaaa attgggcgtc
    19801 tcatttgaac caaaagaaat caaaaacggg gaaatcgtca aaacatacga tcgtaataga
    19861 cgtgccaaac gagaaaaatc aaaagatgta ttagatccca cgctgattgg tcttgtgaag
    19921 aagaaaaaga aaaagatcaa gcctggttat aagaaaaaaa tcgattgggc aattgcagaa
    19981 aaaaataaaa aagaacgcaa aatcgaacgc agacagcaaa gccgtactgc tcgtaaaaat
    20041 aagaaaaatt cacataaata aaaaacaaga ggttgtgaca aaaggcgtgt cacaatctct
    20101 tgtttttaag ctagactttt tttcattccg atacaaagta cttcatcttc aataaaaggt
    20161 tctgtgcaag tatgataccc ttgtttttca taaaaatcta cagccgtcat ttcagctact
    20221 acataactag tctgacaacc ttctgaaacc gcccgttttt cagcagcttc aagcaactga
    20281 ccgcctaacc cttttcctcg gtattctttt gctacgcaaa atcgttccgg cttgaagcaa
    20341 gtaggtgttt tcttttcata acgcaaagta gctactggtc ttttttgatc aagaaataga
    20401 taataggttt gttgcgggat atcttttccg tcgaattcta gttctgcagg aatcccttgt
    20461 tctaatacaa aaacttgata tctcaaaaag cagctagctg cgcgtatcca ttcatccgct
    20521 ccaactattt ttttcatcat attcctcctt gtcatgaata gcagagatgt attgattcct
    20581 ttattcttat cgtaccaaaa atcgtggagt atgaccaaaa ggaaatgaaa ataaaaattg
    20641 agatattgac agtgatcaat agaatgcgta tactaattaa gtacgaaaag gatatgattt
    20701 gttttttaag actcacagaa aattctttct tggctgaaaa aagaatagtc actaatcaaa
    20761 ttgctccctt tttctatttt ggtagaaata ccgacgcagc tcagcgttat cgagtttaag
    20821 aggtaatgat tacacatcat tgcaatcaag gtggtaccgc gagttttcgt ccttggctgt
    20881 gatggtgttt ttttgtattt aatttataga aagcaggtaa tgacatgaaa caattaagta
    20941 gtgcacaagt tcgacaaatg tttcttgatt tcttccaatc taaaggacat acgattgaac
    21001 ctagtgcgtc tttgatcccc gtgaacgatc caaccttatt gtggatcaac tctggtgttg
    21061 caacattgaa aaaatatttt gatggttcag ttgtgccaga aaatccaaga atcacaaatg
    21121 cccaaaaatc tattcgaaca aatgatatcg aaaatgtcgg taaaacagca cggcaccata
    21181 cgatgtttga gatgctgggt aatttttcga ttggtgacta tttcaaaaat gaagccatcc
    21241 actgggcatg ggaatttttg actgatccaa aatggatggc attcgatcca gaaaaacttt
    21301 atgtaacagt ttatccaaaa gatacagaag caaaacgcat ctggcatgaa gaagttggcc
    21361 tgccactaga tcacattatt gatgtagaag acaacttctg ggatatcggt gcaggcccat
    21421 gtggtccgga tacggaaatt ttctatgacc gtggagaagc ttataacgat ttagcagaag
    21481 acgatcctga aaactatcca ggaggagaaa atgaacgtta tttagaaatc tggaacttag
    21541 tattttcaga attcaaccat aagcctgata acacatttga accacttcct cataaaaaca
    21601 ttgatacggg gatgggattg gaacgcatgg tctcaatcgt tcaagatgcg tcaacgaact
    21661 ttgagacaga cttgtttatg cctattatcc acgccgtaga aaagctaagc aaacaagtaa
    21721 aatatggtga aaacccagta acagatattt cttacaaagt aatcgcagat catattcgcg
    21781 ccctttcatt tgctattggc gacggtgcat tgccatcgaa tgaagggaga gggtatgtct
    21841 tacgccgttt gcttcgtcgt gctgtcatgc atgggaaaaa attaggtatt gaacaagcat
    21901 tcttatatcg tttagtccct gttgttgggg aaatcatggt aagttattat cctgaagtac
    21961 ttcaacaaaa agaatttatt gaaaaagtta tccgtacaga agaagaacgt ttcaatgaaa
    22021 caatcaatga aggtttggaa atcttaaatc aagtgatcca agaagtaaaa aacgaaaacg
    22081 ggacgactct agcaggaaaa gacatcttca aactatacga cacatatggc ttcccggtag
    22141 aattaacgga agaggtggca gaagatgaag gactgaaagt tgatcatgct ggttttgaaa
    22201 aagaaatgga tgcacaacgc gaacgtgctc gctctgcccg cagtactgaa aaatcaatgg
    22261 gggtacaatc tgctttattg acagatatca aagtagaaag taaattcatt ggatacacag
    22321 aacaagaatc agatagtcaa ttattggtca tcgttaaagg tgagtctctt ttgaatgaag
    22381 tcgcagaagg tgaagctcaa atgatctttg atcaaacacc tttctatgca gaaatgggtg
    22441 ggcaagtagc ggatcaagga tggatcatga atgaagtagg cgaaatcgta gcagttgtta
    22501 cagatgttca aaaagcgcct aatggtcaat ttatgcacac cgtagaagta aaagcaccaa
    22561 tgagtgaagg acaaacctat catctattga tcgatcaatc gatgcgcaat cggatcatca
    22621 aaaaccatac agcaacccat ctactgcaca aggcattgaa agaagtactt ggcgagcatg
    22681 caaatcaagc tggttcttta gtcgctcctg gacatttacg attcgacttt acccactttg
    22741 gtcaaatcac ttcagatgaa ttagctgaaa tggaaagaat cgtcaacgaa aaaatctggg
    22801 aagctatccc agttgaaaca attgaaacag atatcgatac agccaaaaac atgggtgcaa
    22861 tggctttgtt tggtgaaaaa tacggacatg acgttcgagt agtaaatatt ggcggctggt
    22921 caatcgaact gtgcggaggc acacatgtag caaatacaga aaacatcgga atcttcaaaa
    22981 tcgtttctga atcaggaatt ggtgcaggcg tgcgacgaat cgaggctgta acaagtaaag
    23041 aagcgtacga actacttgaa gaagaagaaa aacaactaaa acaagtagca acaattgtta
    23101 aatcacctca attgaaagaa gttgtttcaa aagcggaaca attgcaacag caagtaagag
    23161 agctacaaaa ggaaaatgaa caattagcta gcaagttagc gaatcaacaa gctggtgatg
    23221 tattcaaaga tccagaaacg atcaatggaa aaacaatcat tgcagcacaa gtaaaagtga
    23281 aagatatgaa tcagctgcgt caattagctg accaatggaa acaaaaaaat atttcagata
    23341 ttcttgtttt agcaaacgaa caagaaggaa aagtcagtct gctagcggca atgacgaaag
    23401 aatcaaatga agctggacta aaagctggcg acttgattaa agcaatcgca ccgaaagtag
    23461 gcggtggcgg tggtggacgt ccagacatgg cacaagctgg cgggaaaaat cctgctggta
    23521 ttccagatgc acttaaagct gcgaaagaat gggttgcgca acaatagggc gtttacgttt
    23581 gacagaaaaa caaaagttca aacattgaac gaaacatgat tatgggggcg aagacaaaca
    23641 agtcttgccc tcatactttt ttcaattgga tggcgcatct aatcaaatgg tcggattcgg
    23701 atggtcttta gttgacgaaa gtgacagaaa tttttacgat tagtataaat aaaaaggggt
    23761 gaaaaaatga atagtagaaa taagaccttt cgactagtct tacgtgcgat cttgttagca
    23821 atcatcatcg tacaagcgat ggttccttgg ctggggttta ttccattagg attcattagt
    23881 ttaacaatta tccatatcac agtaattatt gctgcagtag tattaggccc aaaagatggc
    23941 atggtgattg gcttgttttg gggaatcgct acaattgttc gtgcctatgc catgccaaca
    24001 acgccatttg atacattagt gttcacgaat ccgattatct cggtagttcc cagagtactt
    24061 gttggcttag tagcaggctt ggttttccac tggatttatc aaaaaaataa atcaataacg
    24121 atcagctcag cctttgcagg ggtactgggt tcattggtca atacagtctt agtgttagga
    24181 ttcatgggat tattttatac aggtgcaacg gcagatgcct atggtgtaga ctctgctctt
    24241 ttatttaaaa ccttagcagg ggttgcagca atcaatggga taccagaagc aataggtgcg
    24301 ggaatcataa caccattact agcaaaagcg ttatttgcag caacaccgtt gaaaccagaa
    24361 taatgaccat cttttaatag taataggacg cacgatagat agaaaaagga agagaggaga
    24421 ggaaaacaat cgtcctctcc atctttttac ctgagcaaca agcaaactag aaggggtaaa
    24481 aaacttggct aagaaacaag aagaaaaaaa gaaacaaata ccgcaacagc ggacaaaaaa
    24541 aggagtacta gcgggtatct taggattggt tacgaatctg atcttgtttg tctctaagct
    24601 aatgatcggg cttttttcag gaagtgtctc cattatggct gatgcagtga acagtctatc
    24661 agatactgct tcatccatat tgactttgat cggatttaaa attgctgcaa agccagcaga
    24721 tcaggaacat ccttatggac acgaacgctt cgaatatatc agtgggttat ttgtttcgat
    24781 catcattact tatgtaggat ttcaattttt agagtcttct gctgaaaaaa tcatccatcc
    24841 agaaaatgtc tctttaacac ccatcgtctt ttttgtccta atcatttcca tctttttgaa
    24901 atttgcacaa ggcaaaatgt atcaggttat tgcgcaatcc attgattctg aaacattgag
    24961 agctacagca acagatagtt ataatgatgt ctttactaca ctggctgtat tgctttcagc
    25021 agcaatcgaa tgggtaactg gatggcgtat tgatggatat ataggttttg ctttagcatt
    25081 atatatcctt tatagtggat tgacgatgct tcgaaatttt gtatacgaac tattaggaag
    25141 tcgcccaacg ccagcagaga ttgaagaaat ggaagagcat ttaaatgctt gcgatgatat
    25201 acttggctat catgatttat tggtgcataa ctatggaccc aataaacgct ttgcatcagt
    25261 ccacatcgaa gtagatgaat caatgaattt gaatgtggct cataagatta ttgatctgat
    25321 agaaaaagac tttaaaaagt ctttggatgt ggaacttgtc tgtcacttgg atccaatgcc
    25381 tgttgataac gaaaaatact ataatatctt gcggcagtta aagcaaattc ttcttgaaac
    25441 aggtacaggg cttaatattc atgattttag agtaattcat caaggaaaaa cgctgcaatt
    25501 tgatgtagtg gtccctgaga aattccagtt tgttgataca gaactagaaa gaatcttacg
    25561 tagtcaaata gaagaaaaaa tcggagatta ccaattggaa attacgtttg atcacaatta
    25621 tcttttatat taaatgagaa actataaaaa gactccttaa agtttttaat ttaaagagtc
    25681 tttttttctt ttaattgttt atggagagcc tgacgtgcaa gattatctgc tcctttattt
    25741 ttgttttcgg gcaaccattg caggatcaat aaagaaaatt cggatagaag ttcttggatt
    25801 ctttgaaggt agggaaggaa gagctcgttc ttcgttgcgt ttttgtcgac cgtagaaact
    25861 agtgttttgc tgtctgaaaa acagaaaatc gtttcattct gtaagtcgtt tttctttaga
    25921 aattctaaag tttttaaaaa gacttcgaac tctgcttgat ggtttgtccc tatagaaagc
    25981 gggatagata gctgttcttg tttaccttga tagacaatca agattccacc tccactagga
    26041 ccagggttgc cttttgtaga ggcatcaatg tatactttta acataaaaag agattctcct
    26101 ttttgttcaa actaatgtta tggtaagatt atatcattac tgaatcggtg agaggttaga
    26161 gaatgaaaaa aaatattcga tggcagcctg aactggcaca tacgatcatc tattggtcat
    26221 tgaccttgat cattctgttt tttagtctga ttctttcttt agaaaacaca ggtccttatt
    26281 ggaaaagcaa ttttgtttta ggtatttttc ttgtttttct atttctaggt ttgcggcgtt
    26341 cttttatttt aaaatcaaac tctgtgatta tacgttatgc tgctttttgg aaagaccgag
    26401 aaatatctgt cggacagatt cgatctttga cgccaactaa tactggggtg caaatgatgt
    26461 tgcaagatga gaaagcccca tctgttttca tgatgcgaaa aaaagatcaa gtagtccttt
    26521 ttgatcattt tgaaaaaaac ggacccaaat cagaatcaat tccttatcct tatacgaaaa
    26581 aaagaaaaag ctaattttaa aaatcagaac ctaaaaaaac gaatttttac aggaaaagaa
    26641 aagagtgaga cgtacggttc atcccgttta gcgtctcact ctatttgttt atctattcat
    26701 gcatactagt atcggtagtc tgaacgttgc ctttcttgac atgggcagct tgtgttcctc
    26761 gattcccttc gatgatctca aattcgacca cttgattttc ttccaaagtt ttgaatccct
    26821 cttcttcaat cgcagtaaaa tgtacaaaaa tttcttctgt gtcatcataa ctgataaagc
    26881 cgtatccttt tttgttgtca aaccatttta caattcctgt ggtcaaagca ctcacgacct
    26941 ttctaaagtc tgatcatagc cttcattata aagagtattt ataagtacgt caaataaatt
    27001 aaaaacctgt aattttatgt tttttttctg aataaaaaaa ggtataattg gcatatctta
    27061 acaaagaaga tattttgttg aataaagttc gtgaaaaggg gtaatcaaat gaagaatgat
    27121 ctgcaaattt cacaagaaac agagctagaa ccgattgttg aagtggctag taaattagat
    27181 cttaaggaag acgatttgga actgtatggg aaatataagg cgaaaatcaa tttttctgga
    27241 atcaatcgat caaaggataa cgctgagggg catttgatct tagttacttc catcaatcca
    27301 acaccagctg gcgaaggaaa gtcaacgatc actgtagggt taggagacgc gctcaataaa
    27361 atcaataaaa aatctgttat tgcattgcga gaaccctcac ttggtcctgt gatgggaatc
    27421 aaaggtggtg ctgcaggcgg aggatatgca caggtattgc ctatggaaga tatcaacttg
    27481 cattttactg gtgacatgca tgctatcaca acagctaata atgcattatc tgctctttta
    27541 gataatcata ttcatcaagg aaatgaattg aacatcgatg cccgccgagt gatttggaaa
    27601 cgggtagtcg atctcaatga tcgtgaactg cgtaaagtaa ttgttggctt gggtgggcca
    27661 atccaaggtg ttccaagaga agatgggttt gatatcacag ttgccagcga aatcatggct
    27721 atcttgtgtc ttgcggcaga ccttgaagat ttaaaggctc gtcttgcaag gatcgttgtc
    27781 ggctatacat ttgaccgtca gcctgtgact gctggagact tgaaagcaga aggcgctctg
    27841 gcattactgc tgaaagatgc aatcaagccg aatcttgtac aaacaattta cggaacacca
    27901 gcttttgtcc acgggggacc gtttgccaat atcgctcatg gctgcaatag tattttagct
    27961 accaagacag cattgagatt agcagattac gttgtcacag aggcaggatt tggtgcagat
    28021 cttggcggag agaaattttt agatatcaaa gtacctaact tgaaaaaagc gccggatgct
    28081 gtggtgattg tcgccactgt ccgtgcattg aaaatgcatg gcggaatgaa aaaagatgaa
    28141 cttaaaaatg agaatcttga tgctttgaaa gtaggttttg caaatttaaa gcgccatata
    28201 cgtaatatgg aacaatatca gctacctgtg atcgtcgcaa tcaatgaatt cgtaacagat
    28261 acagacaatg aactcacact gttggagcac ttgtgtgaaa atcaggggat tcttgccaag
    28321 agagcgagtg tatgggcaga tggagcagaa ggcggcgttg atttagcaaa agctgtagta
    28381 cgattgattg atagaaaaga agctaattac aagccattat accgcctaga agaaacgata
    28441 caagaaaaga cagaaacaat cgtcaagaaa atttacggag gaaatggtgt tgttttcagc
    28501 aaaaaagcgc aaaaacaaat agaagagttt acgaagaatg gatgggacaa actgccgatt
    28561 tgtatggcaa aaacacagta ttcattttct gatgatcctt cactgctagg tgcaccggaa
    28621 gatttcacca tcacgatccg cgaaatcatc ccaaaattag gggcaggatt tttagtagcc
    28681 ttgactggag atgttatgac gatgcctggt ttgcctaaaa aacctgctgc attgaatatg
    28741 gacgtgacaa atgacggaga agtgttggga ttgttttaag cttgattata atctaccatc
    28801 gaaggagctg tattttgact acagcttctt tttttagacg atagggaatt aattttgttt
    28861 acactaggat cattcttttt ctttattgta ttttgagcta tactaaagca taataggagg
    28921 gtatgatgaa aacgacattt ataagaaaaa ccggttttta cggtatgggt agctcgattc
    28981 agctaagaat caacaatgaa aaacgcagtg ttctcagtca tgaacaaaag ataacgcttg
    29041 atctggaagt gccctttacg atgcaggtca ccttttattg gctaaaaagc cccgtttata
    29101 cagtgaaaga agcaaagcct gcttatgtga tcacaatgaa ttacttgatt cttcaaatct
    29161 atccgttttt atttctagca actgggttgg gggccgtttt cctacaaaat ttatttttca
    29221 gtttttttgc agttattgtg ttgattgcgt tctttttcta tataaaaaac cgggcatatt
    29281 tgatcaagga ggaaaattat ggcaaactct gatctttttt taatcagttt caatcgaatc
    29341 gaaaaatgga tgagagacga gatgggaaat gcacgaaata tgggatttac cgaacttgtc
    29401 agacgcctag ctcaaagaaa acaattaatg atcagaaaat acgaagatga tcttttacag
    29461 cttgctcagt taaggaatgc gatcgtccat gatcggatcg cagtcgattt tgtcattgca
    29521 gagccaaatg attggacagt caagcgaatc cagctgatcg aacaagaact gattcagcct
    29581 gaaaccgtgc tgcctcgatt tgcaaaacgt gtaacaggtt ttgaacaaga tcttccgtta
    29641 cttgaactgt taaagatagt agcagaaaaa aggtattcac aatttccgtt atacaataaa
    29701 ggaaaatttg tagcattgat tactttacgt aatatcgggt tttggctagc aaaagaaagc
    29761 caaaaaggtc cggttgattt aacaaataaa cgagcgttgg atttgatcat ccaaaacgga
    29821 aagtacacaa attatcattt tgttccagct aaaacacata tttacgaggt tgaagcgatg
    29881 tttcgtgagc aagggacttt ggaagccgta cttatcacta aagatgggaa tcccgatggt
    29941 aatctgctcg ggatcgtacg acctcgtgat atttataaac aaatagaaaa ggattgattt
    30001 tttgttaatt atttattgga tattcagcgc tttgctagta ggagtggatc agttggtcaa
    30061 atggtggatc actgataatc tagcgcttgg agagacgaaa aatcttatac caggtatttt
    30121 gtcactgaat catattcgaa acactggagc cgcatggagt atgctagaag ggaagatgtg
    30181 gttctttact atagtgacac tcattgcagt cgttgtgatt ctcacattga tgattaaaaa
    30241 tcgtgaaaaa ggtaatcgct ggttcatgat tggattgagt ttgattctag ctggtgcgat
    30301 tggcaatttt atcgaccgta ttcgtcttgg ctatgtagta gatatgttcc agacagattt
    30361 tatgagcttt ccgattttta acgtagcaga tgtgacactt gtatgtggag tgatttgtat
    30421 gttaatttat attattttag atgaaaagga tcaaagaaaa aaatgacaga acttaaaacg
    30481 acgattcacc atgaatctgg taggatcgat aaagtattga ctaatttatt caccgattac
    30541 agtcgttcgc aaattcagct gtggctgaaa aatggagcgg tttctgtcaa tggacagcca
    30601 gtcaaagcaa attacaaagt aaaacaagga gacgagatta ctgtcttgat ccccgaacca
    30661 gaaacattag atgtggtccc agaaaatatc ccgttgacga tcgtttacga agatgaagat
    30721 gtagcggtga taaacaaacc tcaaggaatg gtcgttcatc cttcagcagg tcatacgcat
    30781 ggcacaatgg tcaatgcgct gatgtaccat atcaaggatc tttctacgat caacggcgtt
    30841 attcgtccag gtattgttca ccgaatcgac aaagatactt ccggactgct aatggttgcc
    30901 aaaaatgacc aggcacacga atcattagct cagcaattaa aagataagac ctctttgcgc
    30961 aaatatgttg ctttagtcca tggagagatt cctcacgaaa aaggaaccat caatgcgcca
    31021 atcggccgtt cgaaggaaaa ccggaaaatg caggcgataa gagaagatgg gaagtcggct
    31081 gtcacacatt ttactgtatt ggaacgtttc gaaggattta ctctggttga attaaaacta
    31141 gaaaccggaa gaacacacca gatccgtgtg catatgaagt atatcggtta tccgttagct
    31201 ggagatccag tatacggacc gaagaaaact ttgaaaggca atggtcagtt tctccatgcg
    31261 caaatgttag gttttacgca cccgactaca aacgaaaaga tgatctttga agcacctctt
    31321 ccagaagttt ttgaaaaaac tttagaaaaa ttaagaaaaa acattgcatt ttaatttaga
    31381 taacggtata gtaattaaca acgaaagcat aaaacttaat agaattcctt taagtttagt
    31441 cccgtgaggc taagaagggt gggagcaagg atacgtatgg tgcgccataa gtagattgct
    31501 cattgacata gtatagctat cagtgtatca gtatacgctc agtctaaaca ttcctcctgt
    31561 cctcttaggg caggagtttt tttatgcaaa aaagtagggg gaatgaaaat gcaagcaaaa
    31621 gaagtagtag atcaggtaac catgaagcga gcattgactc gaattactta tgagattatc
    31681 gagagaaacc atagtatcca agatatcgta ttggtaggta tcaaaacacg aggaatctac
    31741 attgcatcaa gaattgccga acgcctgaag cagctagaag atatcgatat tcctgtagga
    31801 gaactggata tcactttata ccgagatgac aaaaaagaaa atccagaaga accggaactt
    31861 cattcttctg acatcccagt ttccttagaa ggaaaagaag ttattttgat tgatgatgtt
    31921 ttgtatacag gacgaacgat tcgagcagca atggacgcag taatggattt tggcagacca
    31981 agaaaaattt cattagcagt cctggtcgat cgtgggcatc gagaattgcc aatccgtgca
    32041 gattatgttg ggaagaacat tccaacatct cgggcggaag agattttagt agagatgcaa
    32101 gagcttgatg gacaagatcg catcatgatt ttgaaagagg aagattagag gagagagaaa
    32161 catgtcggag aaaaaaggat ttcataatga tgacgtggtg ttagatatcc acgatcgccc
    32221 aaccccagga cattgggtag gattaagttt acaacacttg ttcacgatgt tcggagcaac
    32281 cgtgttagtc cccatcttag taggtatcga tccaggtatt gcgctagtca gttcaggact
    32341 aggtacattg gtgtacttat ttactactaa aggaaagata cctgcgtact taggaagcag
    32401 cttcgctttc attgcagcga tgcagctttt gatgaaaaca gatggttatc cagcgattgc
    32461 acaaggagca gtcacaactg gattagtcta tttgattgtt gcgctgatca tcaaaaagat
    32521 cggttcagca tggctggata aaatcttgcc tccaatcgtc gtcggtccag tcatcatggt
    32581 tatcgggttg ggacttgcgg caaatgcagc aacaaatgct atgtataatc agggcacgta
    32641 tgatttcaag tatattgctg tagcgctgat cacattagga ttaacaattt tcttcaacat
    32701 gtggctaaga ggttttctcg gattgattcc gattttacta ggtattatta gcggatacat
    32761 cgtagccttg ctgtttggaa tcgtggatac taagccaatc gtagacgctg cctggtttgc
    32821 tgttcctaac tttgagattc cctttgtaca atatgaacca aagctatatc ttggagcaat
    32881 cacaacaatg gcacccatcg cttttgtgac gatgacagag catatcggcc atcttatggt
    32941 attgaataaa ctaactaaac gtaatttctt tgaagaaccg ggtcttcata agacgttgac
    33001 aggtgatgga ttagcacaaa tcgtggcagc ctttgtcgga ggtcctcctg taacaagtta
    33061 cggtgaaaac attggtgttc tggctatcac acgtgtccat agcgtgtttg tgatcggtgg
    33121 agctgcagta tttgcagtca ttttaggatt cgtaggaaaa ttaagcgctt tgattttaag
    33181 tatccctgga ccagtcatct caggaatcag ttttatctta tttggagtaa ttgccgcaag
    33241 tggaatgaag attttaatcg agaacaaaat cgattttgat aaaaagaaaa atctgttgat
    33301 tgcttcagtt atcttagtag taggaattgg cggactcgtc tttgaagtag gcacatttac
    33361 attgtcggca atggcattag caactgtact tggcatcatt ttaaatctta tcttaccaga
    33421 aacttcacga agcgaagaaa actaaggagg aaacattatg atcatcaaat cagaacgtat
    33481 cagcttaaag catttattga ccgttgaggc acttactgat caagaagtta tgggcttgat
    33541 ccgcagaggg caggaattca agcaaggtgc taattggact ccgcaaaagc gccagtactt
    33601 tgctacaaac ctctttttcg aaaatagtac tcgcacacat aaaagcttcg atgtagcgga
    33661 gaaaaaacta gggctagaag tgattgaatt tgaagcaagc acaagctctg tccaaaaagg
    33721 ggaaacacta tacgatacag tactgacgat gtcagcatta ggcgtagacg tagcggttat
    33781 ccgtcatggt gatgagaact attatgacga actgatacaa agtaaaacaa tccagtgttc
    33841 gattatcaat ggaggagacg gaagcggaca gcatccaacc caatgcttgc ttgatttgat
    33901 gaccatttat gaagaatttg gtcattttga aggtctgaaa gttgccatcg taggtgatat
    33961 cactcactct cgcgtagcta aatccaatat gcagatgtta aaacgtctag gcgcacaagt
    34021 attcttctca ggtcctagag aatggtacga cgatgaattc gaagtgtacg gacattatat
    34081 gccattggat gaactactag atcaagttga tgtcatgatg atgcttcggg tgcaacacga
    34141 acgccatgat ggaaaagaaa gtttctcaaa agaaggctac catcaggaac atgggttaac
    34201 agttgagcgt gcgaagaagt tgcaaaaaca tgcaatcatt atgcacccag caccagttaa
    34261 ccgtgatgta gaattagctg attcattagt ggaaggatta cagtcgcgga tcgttcagca
    34321 aatgagcaat ggagtattcg tcagaatggc aatcttagaa gcagtgctaa atggaaaagc
    34381 gtaattatag gaggatgaaa aaatgaaaac actcattaaa aacggtcaga tcaatacacg
    34441 aaaaaatatg acgacaccag cagaaatttg gatagaagat gggcgaatca aagcaatcgg
    34501 tacaggattc tcagaagccg aatttgatga agtgtttgat gcaaagggac aattgatcac
    34561 acctggttta gtggacgtcc atgttcattt gagagagcca ggatttacat acaaggagac
    34621 gatcgaagct gggactcgct cagctgctcg tggcggtttc actactgtat gcgcgatgcc
    34681 gaatttaaat cctgtacctg atacggcaga aaagctgaga caagtatatg acatcattag
    34741 aaaagatgca gttgtgaagg tattgcagta tgcgccaatc acagaaaatc tgcgaagtga
    34801 gaaattagtt gatcaagaag cactgattga agaaggtgct tttgctttca caaatgacgg
    34861 tgtaggtgtc caaacagctg ggacgatgta tctggctatg aaagaagctg caaaaaacaa
    34921 taaagcccta gtagcccata cagaagatga atctttatta tttggcggcg ttatgcacgc
    34981 tggcaagaag gcagaagaac ttggtcttcc cgggatctta agcgtaaccg agtcttctca
    35041 aattgctaga gatctgttgc tagctgaagc aactggtgtt cattaccatg tttgccatgt
    35101 ttctactaaa gaaagtgtcc gtgtaatcag agacgcaaaa aaagcaggaa tccacgtaac
    35161 agcagaagtt tcaccccatc atcttatttt gatcgacgaa gatattcccg aagatttcgg
    35221 cttttggaaa atgaacccgc cgctaagagg acgggaggac agagaagctt tgatcgaagg
    35281 cttgcttgac ggtacgatcg attgcatcgc tacagaccat gccccccatg gattagaaga
    35341 aaaaagccaa agtttcatga aatcaccatt tggtatcgta ggaagcgaaa cagcgtttca
    35401 actgatctat actcattttg tagaaactgg tcgattcacg ttggaacaag tgatcaattg
    35461 gttggcagtt aaaccggctg agatttttgg tttgaatgca ggaacgctaa cggttggtgc
    35521 ccccgctgat gtagcagttt ttgatattac acaaacttgc acgatcgata aagaagactt
    35581 tttatcaaaa ggggagaata caccttttat cggctggaaa gtaaaaggcg aaacacaaat
    35641 gacttttgtc aacggaaaac ttgtgtggca gaagggagaa taaaagtatg gaacgtttgc
    35701 ttatattaga agatggaaca gttttcgaag gaaaggcttt tggtgcagat gctagtgtct
    35761 tcggagaaat cgtttttaca acaagtatga ctggttatca agaaactatc actgatcaaa
    35821 gttttaacgg tcaaatcatt acatttacct atcctatggt gggtaattat ggggtaaata
    35881 gagatgatta tgaatcgatt tctccaacat gcaaaggagt agtagtaaaa gaacatgcac
    35941 gtgtagcttc aaactggcga aaccaaatga cgctagattc atttttgaaa caaaaaggaa
    36001 ttcctggaat atcaggtatc gatacgcgcg cccttactcg caaaatccgt gaagtcggaa
    36061 cgatgaaagc tagtatcgtt gatgctggag attccttcga acatgcattt gatcagctga
    36121 aagcaaccgt tctagcaacc aatcaagtgc agcaagtctc aactaacaaa ccttatccaa
    36181 gtccaggaac aggtcggaaa gtcattgtca ttgacttcgg cttgaaacat agtattttac
    36241 gagaattgag taaaagaaac tgtaacctca cagtacttcc ctataacaca gatgccgaga
    36301 cgattttagc gctatcacca gacggagtca tgctgacgaa tggacctggt gatccaaaag
    36361 atgtgccaga agcaatcgaa atgatcaaaa aaatccaagg aaaagtaccg atttttggta
    36421 tttgtctcgg tcaccagtta tttgctttag ccaacggtgc agatacctat aaaatgaaat
    36481 tcggacatcg aggattaaat cacccggtac gagaagtagc gaccggaaga attgatttta
    36541 cttctcaaaa tcatggctat gcagtcgatg aagccacgat tgatccagaa aaactcatcg
    36601 taactcatgt agaagtaaat gacggaacag tagaaggagt caaacacaga gattatcccg
    36661 ctttcagtgt gcagtttcat ccagatgctg cccctggtcc gcatgatgca ctacatttat
    36721 ttgatgaatt tatggaaatg atggacgcag gaaaggagca gtaaacagat gccgaaacgt
    36781 acagatatca agaaaattat ggtgattgga tctggtccga tcatcattgg tcaagccgca
    36841 gaatttgact acgcaggaac acaagcctgc cttgccttaa aagaagaagg atatgaagtg
    36901 gttttagtaa attctaatcc tgcgacgatc atgacggata aagaagtggc agatcaagta
    36961 tatatcgaac cgatcacact tgaatttgta tcaaggattc ttcgaaaaga gcgtccagat
    37021 gctctccttc caactttagg cggacagaca ggcctcaata tggcaatgga gctggcagca
    37081 tcaggtattt tagaagaatt gaacatagaa cttctaggaa caaagctttc tgcgatcgat
    37141 caagcagaag atcgtgatct attcaaacag ttgatgaaag aattgaatca gccaatcccc
    37201 gagtctgaaa tcgtcaatac agtagaagaa gctgtagatt ttgcaaataa aatcggctat
    37261 cctgtcatcg ttcgtccagc ctttacttta ggcggaactg gtggaggtat gtgtgaaaat
    37321 gaagaagaat tacgtatcgt atcagaaaat ggattaagtc tttcccccgc tacccaatgt
    37381 ttgattgaac gaagtattgc aggttttaaa gaaattgaat atgaagtgat gagagattcg
    37441 gctgataatg caatcgttgt ctgcaatatg gaaaattttg acccggtggg tatccataca
    37501 ggtgattcta tcgtatttgc ccctagtcaa acattgtctg accatgaata tcaaatgctt
    37561 cgtgatgctt ctctttcgat tattcgagca cttaagatcg agggaggctg taatgtccaa
    37621 ctcgctcttg atccacatag ttttaattat tatgtgattg aagtcaatcc gcgtgtttct
    37681 cgttcatctg cgttagcaag taaggcgact ggctatccga tcgctaagct agctgctaaa
    37741 atagcgcttg gattaacatt agacgaaatg aaaaatcctg ttacaggaac gacttttgca
    37801 gaatttgaac ctgcattaga ttatgttgta gctaaaattc ctcgctggcc gtttgataag
    37861 tttgaaaacg gagaacggct tttaggcacg cagatgaaag caactggtga agtgatggct
    37921 atcggtcgga atatcgaaga gtctttattg aaagctgtgc gttctttaga aatcggtaca
    37981 caccatatcg aacttcctga gttggcagac atcacggacg atgacctaat ccaaaaagtg
    38041 gttcgagcac aagatgatcg cctgttttat gtagctgaag ctattagaag agggtacacc
    38101 atagaagaat tagcggattt gacaaaaatc gatttattct ttttagataa actgttgcat
    38161 atcgtagaaa tcgaacagca gttgaaacag cagccgttgg atgacaagat attgaaaaca
    38221 gcgaaacaaa acggttttac agacaaaaaa gtggcggagc tgtgggaaat aaacgaagaa
    38281 gccgttcgcc agatgagaaa agaaaatgat ttgattcctg tatataagat ggttgacact
    38341 tgtgcagcgg aattcgaatc aaaaacacct tatttttata gttcctatga atatgaaaat
    38401 gaaagttcac gatcagaaaa gccctcaatt ctagtactgg gatctggtcc tatccgtatc
    38461 ggacaagggg ttgaatttga ctatgcgact gtgcattctg tcaaagcaat ccagcaggca
    38521 ggatacgaag caatcatcat gaacagcaat cctgaaacag tttcgactga cttttctatt
    38581 tcggataaat tatattttga gccattgacc ttcgaagatg tgatgaatgt gatcgagcta
    38641 gaacagccga taggagtaat cgttcaattt ggtggtcaga cagcaatcaa cttagccgaa
    38701 cctttgactg ctgctggtgt aaaaatctta gggacaacga tcgaagactt ggatcgtgcg
    38761 gaaaatcgtg atttattcga gcaagcgctg aaagagttgg atattcctca acctttaggg
    38821 gatactgcta caagtaaaga agaagccgtg gttatcgctt cgagaattgg ttatccagtt
    38881 cttgttcgtc caagctatgt attaggcgga cgtgcgatgg aaatcgttga aaaccagcga
    38941 gatttagaag attacatgga acatgctgtg aaagcatctc cagaacatcc agtactagtg
    39001 gaccgttact tgcttggtgg tgaatgcgaa gtggatgcga tttgtgacgg tgaaacagta
    39061 ctcatcccag ggatcatgga gcatattgag cgtgctggtg tccattcagg ggattcaatg
    39121 gctgtgtatc cacctcaaac attatctgaa tcgatcaaga aaacgatcga agattacacg
    39181 atccgcttag cattaggttt gaattgtgtc gggatgatga atatccagtt tgtcatccat
    39241 gaaaatgagg tttatgtgat cgaagtcaat cctcgagcaa gtcggactgt tccattctta
    39301 agtaaggtga caggaattcc aatggcacaa attgcgacga aagctatttt gggagagaaa
    39361 ctaaagacac ttggttatga aaacggactt tatccagaaa caaaagaagt tcatgttaaa
    39421 gcacctgtct tttcttttac gaaattgcag aaagttgata cttacttagg gcctgaaatg
    39481 aaatcgactg gagaagtaat gggatctgac agacaattag acaaagcttt gtacaaggca
    39541 ttcgaagctt ctggattaca cttgcctgaa tatggagccg tattatttac gattgcggac
    39601 gaaacaaaag aagaagcact agaattagct aaacgtttta cagaaattgg ctatagtctg
    39661 ataggaacga aacatacagc tgcttatttc gaaaaaaatg gtctggtcgt tgaaacagta
    39721 gcgaaaattt ctgaggaagc agcagaaaaa aatgtagtcg acttaataag agatggtaaa
    39781 acacaagtgg ttgtcaatac gattgataaa gatcggggaa atgcttctaa agacggtttc
    39841 atcatccgaa gagaagcagt tgaacatggt attccattgt ttacttcttt agacacagca
    39901 gatgcgatcg ttcgagtgat ggaatcccgt gctttttcaa ctaaccctat ttaacggcga
    39961 gcacatgtta agacaaaaag acgaaaaacc gttgcaggag gggacagatg aaacaagaaa
    40021 tgatggaaat cgttcagcaa aaacagctgg caccaaagat ttttgaaatg acattgaaag
    40081 gtgatctagt aaaagaaatg cagcaaccag gacagttctt gcatattctc gtgccgcgtg
    40141 cagacttgct attacgccga ccgattagct tgaatcatat cgaccacgaa acaaatactt
    40201 gccgtatcat ttatcgggtg gaaggtgagg ggactagagt cttctctact ctttctgccg
    40261 gagaccattt agatgtcatg ggtcctttag gcaatggttt tgatttgtcc aatcttcata
    40321 caggagacga agtatttata atcggtggag gaatcggtgt ccctcctcta tatgagttat
    40381 caaaacagtt agtcgaaaaa ggaattaagc caacgcattt tttaggtttt gccacacatg
    40441 aagtcgttta ttatgaaaaa gaatttaatc gtctaggaga aacaagaatc gctactgacg
    40501 atggaacata cggtatgcac ggaaatgtcg gtaatttatt gttaggaacg aagacggaac
    40561 ctacagctgt ttttgcatgt ggttcaaacg ggttattgaa gacagtggaa cagctgtttt
    40621 cttcgcatca aaatgtccag ttatcattag aatcccgcat ggcatgtggg ataggggctt
    40681 gctatgcttg cgtttgtcat acgccggaag atgaaacagg aacaaaaagt gtgaaagttt
    40741 gtgacgaagg accgattttt aaaataggag aggtaattat atgaatgaga atcctttagc
    40801 ggtcaaactt cctggcctag aattaaaaaa tcctatcatg ccggcaagcg gctgtttcgg
    40861 ttttggcaaa gaatacggaa aatactatga tttgaatcag cttggatcga tcatggtcaa
    40921 ggcaacgact ccaaatgccc gctttggcaa tcccacgcca agagtggcgg aaacaccatc
    40981 tggcatgttg aatgcaattg gtttgcaaaa tcctggtcta gacgttgtta tgcataaact
    41041 tcttccagaa ttagaggagt acaatgagtt acccatcatc gcaaatgttg ctggtgcttg
    41101 tgaagaagac tatgtagaag tttgtagcaa aattggcgaa gcaccaaatg tgaaagcaat
    41161 cgagctgaac atttcttgcc caaatgtcaa acatggcgga attgcttttg gaacagattc
    41221 tgatgttgct tttcaattaa cacaagcagt aaagaaagtt tcttctgttc ctgtctatgt
    41281 caaattgtcc ccaaatgtaa cagacatcgt tccaatcgct caggcaatcg aagctggagg
    41341 ggcagatggg tttacgatga tcaatactct tcttggtatg cggattgacc ttaagacaag
    41401 aaaaccgatt ttagccaatc aaacaggtgg actctccgga ccagcaatca agcctgtcgc
    41461 tattcgtttg attcaccaag tagcaagtat atccagcctt ccaatcattg ggatgggcgg
    41521 cgtgcagaca gtggatgatg ttcttgagat gtttatggct ggagcaagtg ctgtagctat
    41581 agggaccgcg aatttcaccg atccgtatat ctgtcctaaa ctaattaaag agctccctgt
    41641 gcgaatgagc gaactaggca tcgaatcgct ggaaagatta atcaaagaag tgagagagga
    41701 acgtgaacga tgaatcaact agaccaacga ccaattattg cattagattt ttcaactagg
    41761 caagaggtag aagactttct tcgatttttc ccgaaagaag aaaaattgtt tgtgaaaatc
    41821 ggaatggaat tgttctacca agaaggacct gaaatcgtac gttatctaaa agaggctggt
    41881 cataatgtat ttttagatct gaaacttcac gatattccga atacggtcga aaaagcaatg
    41941 cggggattgg caaagcttgg tgttgatctc acctgtgttc atgccgctgg cggtattcgt
    42001 atgatggagg cggcaatgcg aggattagaa gaggggactc cagaaggtgg aaaacgtccg
    42061 ctacttctag ctatcactca gcttacttct acaagtgaag aagaaatgca tgccgatcaa
    42121 ctaatcgaag tttctttaga aaaaagtgtg atccattatg ctagctgtgc caaaaaagca
    42181 ggattagatg gtgtggtttc ttctgcttgg gaagtagaag cgatcaaaga aatggcagga
    42241 gacgaatttg tttgcttaac tccgggtata agaccagaag gaacagtcgc aggagatcag
    42301 acaagagtag tcacaccttc tcaggcaaaa aagatcggct caacttttat cgttataggt
    42361 cgaccaatca ctcagtcaac taatccttat aaagcatatc aaacgattca aacagaatgg
    42421 agctaaccta aaatgaatgt tgaacaaagt atcgcaaaag acttattaga aattgaagca
    42481 gtatttttaa atccaagtaa tccttttaca tgggcaagtg gaatcaaaag cccaatttac
    42541 tgtgataacc gaatcacgat gagctatcca aaagtccgaa aagagatcgc aaaaggatta
    42601 gcaagcaaaa tcaaagaagc ttaccctgaa gtacaagtga ttgctggaac tgcaacagca
    42661 ggaatccctc atgccgcatg ggtagcggaa atactggatt tgccaatggt ctatattcga
    42721 agtaaggcga aagatcatgg gaaaggtaac caaatcgaag gacgtatatt tgaaggtcag
    42781 aagatggttg tgatcgagga tttgatttct acaggcggaa gtgtcttgga agcagctgaa
    42841 gcagcaaaaa gagaaggtgc ggatatcctt ggtgttgcgg ctatctttac gtatgagttg
    42901 ccaaaaggaa aagcaaattt cgaaaaagcc gaaatccctc ttatgacgtt gaccaattat
    42961 tctgtattga ttgaagcagc tttagaagat cgttatatcg atgagcaaga attaactctg
    43021 ctaaaagaat ggaaaaaaga tcctgaaaat tggcagattt aagcgcgctt gatgaagata
    43081 gagaaatccg atttgtgtct ccagaatcat caattggaat agcaaaaatc caaaaactga
    43141 ttgcgagaag catcttttca tcaggtatga aaagaaactt ctatcgtgat cagtttttga
    43201 tttttttaaa attcattttt ctaagactgg ttagcagaaa gaagagaata atctcttctc
    43261 ttttttctat tatatataga ttttctctat tttttggtaa gggagctgtt tcaaaaatgg
    43321 taaagagcgg aaatgttgcg aatatcagtt atttaatgat atgatattcg gaaaaagaaa
    43381 tctcaaaggg aggtaacttt tatggggttg aatgaattta ttttaggatt gaacaattta
    43441 gagacgatca caagggcacc tggatttttt aaatatacag agcatacagt tgcagcacat
    43501 tcgtatcgtg tagcatctat tgcgcaagtt ctaggagaca ttgaagaagc gaatggacaa
    43561 ccgatcgatt ggaaactgct ctatgaaaaa tcattgaatc atgactacac agagcgtttt
    43621 attggtgata tcaaaacgcc ggtgaaatac gcaagcaaag agttaagagg gatgctgcaa
    43681 acagttgaag aaaagatgac ggacgaattc atcaaccaag agattccagc tgagttccaa
    43741 gaagtttatc gccgtcggtt gttcgaagga aaagatgaaa ccgtagaagg agaactatta
    43801 gccatttcag ataaggttga ccttctttat gaatcttttg atgaaatcat caaaaataac
    43861 ccggaaaaag tttataagga gatgttcatt gaggcagtga ctacgattaa aagctttgaa
    43921 catcggcctt ctgttcagta tttctttaaa gagatatttc cggaactatt gaaccaggaa
    43981 ttttatggaa aagaggcgtt tttagaaacc gtctcaacga ttgtaaagaa agaagaaaaa
    44041 taaaaatgat atgagatgca gggggaagta tagttgaaaa agaatatgga tgtcgaatgg
    44101 ggctattctg gagacaaagg tccggaaaat tgggcgagtt tatgtgattg gtttgcgaga
    44161 ggtgcggaat ttccattgca gtcgcctatt catttgacca agggggaaga aaccaaaata
    44221 gaaggagaca cgctttcctt tcattatcaa aagcaacggt ttactgacaa ggaattcaaa
    44281 aacacgattc atttagtacc ttttgaccaa ctcagttatg tagagttcaa gaaagaacgc
    44341 tattatttga cagatattca tttccacttg ccttctgaac atatcatcaa cggaaaacag
    44401 gaagatattg aatttcattt tgttcatatg aacagcaaaa aagagaatct agttgtgggt
    44461 gtcatgtacc agctaatggt acaggaaggt tggctgtata atcaagaaaa tggggaaagt
    44521 tggaacttag aaaaacatga gcattgggta aatccggatg tgttctttcc ggagcaaaaa
    44581 agccatttcc attatattgg ctcattgaca actccgccta ccagcgggcc aatccaatgg
    44641 tttgtaatgg atcatgtagg aaaactgaac caagagtttc ttctcccctt cgatggtcag
    44701 tatgctcgac cgaacaaccg accaatccag cccttgaatg gaagagaaat ttattatttc
    44761 gaggagtttg agcaatgaat attcagcaga tgaaatacgt ggtcgctgta gcaaacaatg
    44821 gtagtttcag agaagcggca aagaaaatgt ttgtctccca gccaagtctt tcagctggta
    44881 tcaaagaatt agaaaccgag ttagggatca cgctgtttac tcgaacgaat cgaggggcat
    44941 atttaacaga agaagggcaa gacttcttaa atcgtgccga gaaaatattg gtccagcttg
    45001 atacattaga aactcactat ctaacgagtg aaaagagaga caatttttcg atcgctgccc
    45061 agcattatga tttcttaggt cctttgaccg cacagctact cgaggaattc aaagacgaga
    45121 tcaaacaatt tcggatcatg gagacgacaa cagcgagagt gatcgaagaa gtcaaagagc
    45181 agcacagtga gatcggcatt atttatatga atgagcataa tcaagctggt atcagaagat
    45241 atttacaaca aggagagcta agtggccgca gcattggaaa attcaaaacg catatttttt
    45301 taaggcaagg acatccatta gctgaacacg cagagatcac caaagaagaa ttgttatctt
    45361 atcctcaagt tcgttttaca caggatggaa ataatttccc gtatttttat gaagacctta
    45421 tcgagatccc tgatcaagaa acagtgattt atacgagtga tcgaggtact ttgatgaata
    45481 tcgttcttga aactgatgct tacgcttcag gatctggtat tgtgattgga gggattcgcg
    45541 agcacttgcg gttaatccct ttggcagaag gcgaactaaa tgaattttat atcatttatt
    45601 cggcgaaacg tccgctcagt gaaatcgctc aaagatttat caaagagctt actcggttac
    45661 tggaccagca gagctaagaa aagcagatga gaacgctgtt tattgaacac cgttgatcaa
    45721 aaaagagggg ttgtgacaga attttgtcac aactcctctt tttgtagcaa acaatttata
    45781 actaattgct gttgtgggaa agtacgcaaa tatgattcta gaaacactca ttgattacct
    45841 gttttgtttc atagctgtaa ttttttcttc ttctggtgtc acgataatcg tcttttggtt
    45901 ttcataaata acataaccag gcttggcgcc atttggtttt cggatatgct ttacctgtac
    45961 aagatcaacc ggcacttggg cagagtatcg gtattttgaa aaataggcag ctaactcggc
    46021 agcttctgta attgtttcat ctgagggctt gtcactttta atgatgacgt gcgaaccggg
    46081 tatatttttt gcatgaagcc aatagtcggt ttttttagct gtcttcattg tcagctggtc
    46141 attttgaaga ttgtttttac caacaagaat gagcgttccg tcagaagaaa agtattgatc
    46201 aggctgagat ggtttcttac gtttttgttt ttttaagttc ttctttttca ggtatccttc
    46261 tgaagtcaat tcttctttaa ttgcttcgat atccattggg ccggcaattt ccagttgaga
    46321 taagacagat tcaagatatt ggatttcatc tttggcttct tggatttgtt cgccaatcag
    46381 cttaacagcg ttcttcagct tttggtatcg atggaaatat ttctgtgcat tttgatttgg
    46441 tgtcaatgcc ggatctagtg ctattttgat tggccgatct tcttcataat aattaggtaa
    46501 aacaacttct tttgcgccgc gtggtacttg tgtcagaaaa gtagtaagta gttcgccatt
    46561 tctacggtaa ttctcagcgt tttcggattc tttgagtgtt tgttcacgtt ttttcaattt
    46621 atttttattt cgttttagtt cattttcgat ttttcgaatc agttctccgc cttgttgttt
    46681 tgcccgatct ttctctgctt tttcgtgata atagctatct aataattgac tgagtgttgg
    46741 ataagctgtt acagcagatg cctgttcgga caatacctga taagcaatcg gtgtgaaaaa
    46801 atctttattt tccgtttcgt aaaaagtagg aataggctga tggctgatgg ctgagaaaaa
    46861 ttcgtcccat acaaccatct tttcattagg acgttccagt aatcttttgg tcagctcttg
    46921 agcgatatcg aaaccgattc cctgaaactg acgttggatt gcttttggat ctagttcagt
    46981 ttgggaaagc cgctgaaaga ttttttcttt ctcggagcta aatgggttca agacctcttg
    47041 ttttggcgga gcaacatatt ctacaccagg aagcaaagaa cgataagtgt tttgagagct
    47101 tccaatgtgt ttgatcgcat ccagtatttt tccagtttct cgattaacta agacgatcgt
    47161 actatgacgt cccattaatt caacgatcaa tatgatattt tgtagatcac ccaactcgtt
    47221 tcgtttagca aagtggaaat ggatcactcg atcattttcg atttgttcga tgtcttctaa
    47281 aatagcgcca tccaaatatt ttcgaagcat catcacgaag ttaggcggat tatcaggatt
    47341 ctgataatcg atttgggtaa tctgtacacg agcataactt gggtgcgcag ataataataa
    47401 tcgatggttt ttgccgcgtg aacgaatcac cagcacgatt tcattttcat aaggctgatg
    47461 gattttcgag atccggccag atagtaacgt ttcacgcaat tcgttgacca tcgcgtgggt
    47521 aaatacacca tcaaaggaca tggttcattc ctcatttctt ttcataagta tattcattat
    47581 aacgaaaaaa agaagaaaaa ccaatttggc cgaatagtaa agcaaaagtc tagaaaaatc
    47641 ttggactaat tacataaaaa acagtgtttc tatcgttgaa atccaaattt ttaggt
//
LOCUS       DAPBCF010000019        47432 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.019, whole genome shotgun sequence.
ACCESSION   DAPBCF010000019 DAPBCF010000000
VERSION     DAPBCF010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.019"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(17..751)
                     /locus_tag="RD508_001296"
     CDS             complement(17..751)
                     /locus_tag="RD508_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HDT7735906.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1078..1488
                     /locus_tag="RD508_001297"
     CDS             1078..1488
                     /locus_tag="RD508_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDT7735907.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1481..2182
                     /locus_tag="RD508_001298"
     CDS             1481..2182
                     /locus_tag="RD508_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDT7735908.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2182..3768
                     /locus_tag="RD508_001299"
     CDS             2182..3768
                     /locus_tag="RD508_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7735909.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3787..4008
                     /locus_tag="RD508_001300"
     CDS             3787..4008
                     /locus_tag="RD508_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HDT7735910.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4005..4766
                     /locus_tag="RD508_001301"
     CDS             4005..4766
                     /locus_tag="RD508_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HDT7735911.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5146..5655
                     /locus_tag="RD508_001302"
     CDS             5146..5655
                     /locus_tag="RD508_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDT7735912.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5730..6269)
                     /locus_tag="RD508_001303"
     CDS             complement(5730..6269)
                     /locus_tag="RD508_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HDT7735913.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6409..7020)
                     /gene="rpsD"
                     /locus_tag="RD508_001304"
     CDS             complement(6409..7020)
                     /gene="rpsD"
                     /locus_tag="RD508_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDT7735914.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7282..8133
                     /locus_tag="RD508_001305"
     CDS             7282..8133
                     /locus_tag="RD508_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDT7735915.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8161..8796
                     /locus_tag="RD508_001306"
     CDS             8161..8796
                     /locus_tag="RD508_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDT7735916.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8816..9589
                     /locus_tag="RD508_001307"
     CDS             8816..9589
                     /locus_tag="RD508_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7735917.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            9997..10794
                     /locus_tag="RD508_001308"
     CDS             9997..10794
                     /locus_tag="RD508_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HDT7735918.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10772..11185
                     /locus_tag="RD508_001309"
     CDS             10772..11185
                     /locus_tag="RD508_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDT7735919.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11169..13814
                     /gene="mutS"
                     /locus_tag="RD508_001310"
     CDS             11169..13814
                     /gene="mutS"
                     /locus_tag="RD508_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDT7735920.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISSVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13832..15940
                     /gene="mutL"
                     /locus_tag="RD508_001311"
     CDS             13832..15940
                     /gene="mutL"
                     /locus_tag="RD508_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDT7735921.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15962..16522
                     /gene="maf"
                     /locus_tag="RD508_001312"
     CDS             15962..16522
                     /gene="maf"
                     /locus_tag="RD508_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HDT7735922.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16607..18595)
                     /gene="treP"
                     /locus_tag="RD508_001313"
     CDS             complement(16607..18595)
                     /gene="treP"
                     /locus_tag="RD508_001313"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HDT7735923.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18818..19531
                     /gene="treR"
                     /locus_tag="RD508_001314"
     CDS             18818..19531
                     /gene="treR"
                     /locus_tag="RD508_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HDT7735924.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19608..20054
                     /gene="msrB"
                     /locus_tag="RD508_001315"
     CDS             19608..20054
                     /gene="msrB"
                     /locus_tag="RD508_001315"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HDT7735925.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATEQPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20224..20826
                     /gene="ruvA"
                     /locus_tag="RD508_001316"
     CDS             20224..20826
                     /gene="ruvA"
                     /locus_tag="RD508_001316"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDT7735926.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNEKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20839..21840
                     /gene="ruvB"
                     /locus_tag="RD508_001317"
     CDS             20839..21840
                     /gene="ruvB"
                     /locus_tag="RD508_001317"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDT7735927.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21869..22447
                     /locus_tag="RD508_001318"
     CDS             21869..22447
                     /locus_tag="RD508_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7735928.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22499..22981
                     /locus_tag="RD508_001319"
     CDS             22499..22981
                     /locus_tag="RD508_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HDT7735929.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIAIEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23098..23472
                     /locus_tag="RD508_001320"
     CDS             23098..23472
                     /locus_tag="RD508_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735930.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(24150..25502)
                     /gene="brnQ"
                     /locus_tag="RD508_001321"
     CDS             complement(24150..25502)
                     /gene="brnQ"
                     /locus_tag="RD508_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDT7735931.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            25649..26239
                     /locus_tag="RD508_001322"
     CDS             25649..26239
                     /locus_tag="RD508_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HDT7735932.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(26367..27716)
                     /locus_tag="RD508_001323"
     CDS             complement(26367..27716)
                     /locus_tag="RD508_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7735933.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(27884..28624)
                     /locus_tag="RD508_001324"
     CDS             complement(27884..28624)
                     /locus_tag="RD508_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7735934.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(28637..30229)
                     /locus_tag="RD508_001325"
     CDS             complement(28637..30229)
                     /locus_tag="RD508_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDT7735935.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            complement(30797..31093)
                     /locus_tag="RD508_001326"
     CDS             complement(30797..31093)
                     /locus_tag="RD508_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735936.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            31269..31994
                     /locus_tag="RD508_001327"
     CDS             31269..31994
                     /locus_tag="RD508_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDT7735937.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            31987..32829
                     /locus_tag="RD508_001328"
     CDS             31987..32829
                     /locus_tag="RD508_001328"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HDT7735938.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            32832..33353
                     /locus_tag="RD508_001329"
     CDS             32832..33353
                     /locus_tag="RD508_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HDT7735939.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(33606..34169)
                     /locus_tag="RD508_001330"
     CDS             complement(33606..34169)
                     /locus_tag="RD508_001330"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDT7735940.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            34420..34689
                     /gene="rpsO"
                     /locus_tag="RD508_001331"
     CDS             34420..34689
                     /gene="rpsO"
                     /locus_tag="RD508_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDT7735941.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            34877..37003
                     /gene="pnp"
                     /locus_tag="RD508_001332"
     CDS             34877..37003
                     /gene="pnp"
                     /locus_tag="RD508_001332"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDT7735942.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            37513..37779
                     /locus_tag="RD508_001333"
     CDS             37513..37779
                     /locus_tag="RD508_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7735943.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            37956..39914
                     /locus_tag="RD508_001334"
     CDS             37956..39914
                     /locus_tag="RD508_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HDT7735944.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            40268..41569
                     /locus_tag="RD508_001335"
     CDS             40268..41569
                     /locus_tag="RD508_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDT7735945.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(41699..43069)
                     /locus_tag="RD508_001336"
     CDS             complement(41699..43069)
                     /locus_tag="RD508_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDT7735946.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(43251..43574)
                     /locus_tag="RD508_001337"
     CDS             complement(43251..43574)
                     /locus_tag="RD508_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HDT7735947.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            complement(43899..44507)
                     /locus_tag="RD508_001338"
     CDS             complement(43899..44507)
                     /locus_tag="RD508_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HDT7735948.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            44837..45553
                     /locus_tag="RD508_001339"
     CDS             44837..45553
                     /locus_tag="RD508_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HDT7735949.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            45566..46261
                     /locus_tag="RD508_001340"
     CDS             45566..46261
                     /locus_tag="RD508_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HDT7735950.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            46345..46974
                     /gene="udk"
                     /locus_tag="RD508_001341"
     CDS             46345..46974
                     /gene="udk"
                     /locus_tag="RD508_001341"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HDT7735951.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
BASE COUNT        15378 a         8781 c         9871 g        13402 t
ORIGIN      
        1 tttatttagc ttttgattaa gccataaata ataatttata taagaatact gctacgacac
       61 cagcacagat aggtgctaca actggtaccc atgcatatcc ccattgagaa gaacctttat
      121 gtttcaatgg aagaagtgcg tgtacaagac gtggagcaaa gtcgcgggct gggtttagtc
      181 caggacctgt aggaccacca agtgaagcaa ctaatgtcca tacaaggaaa ccaagtgcta
      241 agtgagctgt accaagatta tcttggaaga atggtgcttt tgtaatacct agggcaccaa
      301 agaataaaac gaatgaacca aagaattcat tgacgaaacc attgaattta gaaccaacgc
      361 tgttgattgt tgagaatgta cctaacacat ggtttacgtc ttctgtttgg tcgtagtaag
      421 gtttgtaaca agctactacg atcaattgtc caatcgctgc accaatcaat tgtgcaatga
      481 tataaggaac aacttcagcc caagggaata gaccattaga tgctaaagca attgtaaatg
      541 ctgggttgat gtggttaccg ctgattccac caaaaatcat tgctggcatc ataaccccga
      601 atccataccc gacagcaatc agcatccagt cactgccata tccttttgta ccttttaaat
      661 ctacgtttgc tacagcaccg ttacctagaa cgattagtaa tgctgtacca atcatttccg
      721 ccgcaagacg ggtcattagt gagtaatcca taaatacctc caaaagttat aaaaatgcaa
      781 aaaaaaaaga aacatcaaca cgaaaagcat cggtgcagtg tttcgtgtcg gaaggatttc
      841 tgcagtctta acaaatgtga ataaaaaaat gaattccatt acttataaga aaccagacca
      901 acagtaaaac tccaactctt tttaaaagtt ctccacaaat caccaagctt aactataaat
      961 ataccaaaaa aaaaacgttt tttttctcaa aaattgtatc ttagaaacag catgttttga
     1021 aactttcaga aaaggtttgt tagtaaaatg aaagctatac gtaaggagtg ttgtttgatg
     1081 aaattttttc aagagttttt cattattatt ttcttttctg tattaggaga aggcatacgg
     1141 atttttgctc atttacctat tcctggaagt atcttaggta ttcttttttt atttttagca
     1201 tttgaaatgc atcttgttga tcctgaaaaa atcggagcaa ctggtgattt tttattgaat
     1261 aatctagcca ttttatttgt tcctgctggt gtaggtttat tggaatattt tgatgatatt
     1321 gcttcgatat ggcctgtttt actgggagca gtcgtcgtgt gttccatcgt cacgatggtt
     1381 gcagcgggaa aaacggcaga aggtgtagaa gctttgctgg gctatgtccg taagaaaaaa
     1441 gcagaaaggg tatctgtaaa cgaaatggag gagaatcaaa ttgactgagt tttttgtgaa
     1501 tccattattt ggcttaagtt tgactttagg agtgtacgta ttatctgaca aatttttgcg
     1561 gaaatataaa ctgcctgttt tgaatcctct cgtattatcg attgttgtta ttatcttatt
     1621 tttgcatttt tctgggatca gctataaaga ctataatatc gggggcaatt ttttgactat
     1681 gctgattact cctgcgacag tggcacttgc catccctctt tataaaaact tccgtttact
     1741 gaaagagaat ttttatcctg taatggctgc gattttagca ggaatagtcg caaattgctt
     1801 ggttagtgta gggttcggtt acttcttctc tcttcataaa gagatggtga tctcattact
     1861 acctaaatct gtaacgacgg ctatttctgt cgatttatct catacgatgg gcggggtgaa
     1921 tgccgtgaca cttgctattg ttgtctctac aggtattttt ggttcgctga tcgccactca
     1981 tattttccgc ctattcaaga tcgaaagtcc agttgctcgc ggtgtggcgt taggaagtac
     2041 ttctcatgct attggtacag caaaagcaat cgagattggt gaaatagaag gaatcatttc
     2101 cggacttgcg atatgcgtca acggaatatt gaccgtttta ttgctaccgt tattctttca
     2161 gccttttgct ggcttgtttt gatgcgaaaa ccactatttt atgctacaat aaccaaaacg
     2221 ttcgagcata aaaaaggagg gaaagacgtg tatttgtctt ccgagtatct taaacaattt
     2281 gataaagatc tatattataa gattctcctc ctagaaagtt ttgaggatca agcttggcat
     2341 accgctgcac aattagcgca agttgttcag ctggatgccc gcagcgtgtc gaaatacctg
     2401 aacgagctgt ctaaaaacta tcagcagttt agcggtaaga cacacccttt gtttacaaaa
     2461 aatcaccgtt ctggttataa cttttatgat acgctcgatt caattgaaca tgagcgtttt
     2521 ttgatctatc tcgtgcaaag tacgctgaaa ttccagttgc tgcacgacat tttttttgaa
     2581 gaattccata caatgtacca atttgcgcaa aagcattaca ttagtgaatc tactgctcat
     2641 cgaaaaatca atgaatggaa acagcaactg caaacttacg gaattcggct gcaacgaggt
     2701 acatatatcg ctcaaggcga agaagaaatc attcgacttt acttgcatat gacattctgg
     2761 cagttgtttc gagggaaaat ctggccattt gaaacgattt ctcaaatgga cgtaaagaat
     2821 atggcagaac atatcatggc tttttttaat gttcgtctga acgagatcaa aaaaagacga
     2881 ttggaatata tgctaggtgc ctttttttta agaaaatcac agaagcatta tgttgtattg
     2941 aatgagaaaa aaagacggct gatttctgac aatctgttgt tccagcgatt ttgccaggtc
     3001 atggagccgg tatttcctaa ttattttcaa gtagaagacg agttaggcgc attatttctt
     3061 gtactgatga ctcgtgaaga atattatagt gatcctaaga tacggaagaa aatttttgat
     3121 tttcatcaac aagcaaaaac accgcccttt acagcccttt cagaagcaaa agccgctctt
     3181 tctctttatc aggaagagca ggggctgcca gcagaaaatc taaccttcga ggcagaaaac
     3241 tatttattca gcagtcattt tttcgcctat ctttttccta atgcgaaaga aacgattgat
     3301 ggcaatagta gtgattttat taatcattta gttattgaaa acaaggaatt gaaacaatgg
     3361 ctcgtacatt tttttgaaag tagacacaaa catcccaatc atctggcatt taaaaatcat
     3421 gcgtttttga tggggcggta tctgactgtg tttaaaacat taggagcctt tactccacag
     3481 cttccaaaga tcacgatcct tttaatgaca gatttcccat tatttgaaga gcaactgtta
     3541 gaggagggat tacggacatt tttccgtaat gagtatcagc tgatttttct gccaacagat
     3601 tatcggggga gagaagttga tcttctgatt tcgacaagta aagtccaccg caaaccatgg
     3661 gcggatcttg actattttat tgtgactgaa gaactaaaat taattgatta catccaacta
     3721 tctcaaaaat ttgaaatgat tcaaaaacaa aaactattaa aacaataaca aagaaggaga
     3781 aaaaagatga catttgaaga aattttacca gaattgaaaa aaggtgcaaa gattattcgt
     3841 aaaggatgga gtggatttga actttatgtt gttctcgtat ccgatgatga atttgatggc
     3901 tgtccggtga cgccgtactt attgatcaaa acaagtgacg aaggtttttc cagcttcgct
     3961 cctacagttt gtgatatttt agcagatgat tgggcgatcg tagaatgaaa aaccagtatc
     4021 cagatctagc taaacaggtt gtatttatca caggagctgc ttctggaatt ggtgctgcgc
     4081 aagcccgagc gtttcttgaa caagatgctt ttgtatttgg attagatcaa aagttcggta
     4141 aaatggaaga aatttctttg cgatttcctg aaacttttgc ctacgcacta ggtgatgttc
     4201 gacaaatgaa agaactccaa caagcggtat cgaaatgcca aaatcatttt ggtgaagtta
     4261 cgattttact gaatacagcg gggatattgg atgcctacaa acccttgatg gaaactgacg
     4321 aatcgctgtg ggatctgatt tatgagacga atgtgaaaag catgtatcag ctgacaaaaa
     4381 tcatccttcc tgatatgatc cgccaaaaaa gcggaacgat catcaatatg gcttcgattg
     4441 ctggcttgat tgctggtgga ggtgggatcg cttatacaag cgcgaaacat gcgattgtcg
     4501 gatttaccaa acaactcgct ctggattacg caggacaggg tatccgagta aaaggaattg
     4561 ctccaggagc catccaaaca ccaatgaatg cggctgattt tgaagggaaa ggtgagatgg
     4621 cagagtgggt ggcaaatgaa acaccagtca agcgatgggc acagccggaa gaagtagctg
     4681 agctgacgtt atttcttgcc tctcctcaag caagctacat acaaggaacg atcatcccaa
     4741 tcgacggcgg atggttgtta aaataacctt gtgttttttt caagcttctg tatgataaaa
     4801 ctaaagagag aaacaacggt tgatgataaa aaaagtcgat gactgttccc gacattcgat
     4861 gccgaacagc cagttcaaaa aattcttttt aataatcgtt aatattcgaa actaagcggc
     4921 ttttcacgac ctcttgatat aaacgatatt caaaagcttg caactgcggt aacaagtcca
     4981 gccaaatgaa aaatataagg agctattttt atttgaccat tcttattact tgttgcaggg
     5041 cagctttttc actaccttct gcgacacttc agttggaatt ttcttcccat cctttggtcg
     5101 cggtcattac caagataaaa ttatcttgca aaggagaaat agaacatgga aaaaaataat
     5161 acccgttcag ccaaacgctg gacaacgaca gatgtgactc ggatggcgct agtcactggt
     5221 ttatatgtgg cagtgacgct ggttttgtct gtctttagct ttggagtgat tcagattcgt
     5281 ctctcggaga tgttcaacta tctgtccttg tataacaaaa gatacatcgt cgcggtaaca
     5341 gcgggagtag ctttggctaa tattgcttct cctcttggac tgatagatgt tgcagtagga
     5401 agcgtcagca cgctgcttgt attgcttatc aactataaaa tcactagtcg catcaaaaac
     5461 atgaaaatca aaatggccgt gacagcatgc gtatttgctt tttccatgtt tacagtagct
     5521 ggtcagctaa cgattttata tcaactacct tttttcttga attggtgggt gattgcttta
     5581 ggagaattgg catcaatgat tgtcggtggg ataattattt attggatcgg taaaaaagtg
     5641 gatttgtcaa aataaagatc tgtttaattt aaaatagggc agcatggaag agactgaatg
     5701 ttgagtcttc ttccatgctg cttttttgat taatttgtat gaagaaatcg atttagccgt
     5761 tttttcatca agataccgat ataagctgct ccagttgcct tgattgcttc cggcagtaaa
     5821 aacggcagta gtccactggc aaatgcagtt gtaaaagtaa gatcaccact tattttcagc
     5881 cagatcgttc cgcagatcaa tgcagcaaga gagcccatta gattggcaaa gattgcatat
     5941 aagtaatgag catccgttct ttcgatcatc caaccagtta tccacgtttg taagagaaat
     6001 ccaatcaaat atccgccagt tggcccaaat aaaacagcta tacctccagt catccctgaa
     6061 aatacaggaa gaccaatcaa gccaagtaaa agataaactc caacagatat caatcctagt
     6121 tttcttccga gaaaagttgc tgttaatcca atagcaaatg tttgccctgt caaaggaacc
     6181 aaaccaaaag gaatggtcat ctgagaaagg acagaaataa tcgcggcaaa ttccgcagca
     6241 agtatcaatt ctttcaatgt tcggttcata acgccctctt ttcgttaact taatattttt
     6301 atttggttaa cgaaattgta aaacaaagtg attactttgt aaatagaaaa tataaaaaaa
     6361 gaccagctat ccaatagata gcggtctttt tcaagaaagc ttttgaaatt ataagctttg
     6421 gttgtagtat tcaacgacaa gagcttcgtc gatttctgga tatagttcgt cacgttctgg
     6481 taaacgagtc aatgaacctt ccaatttttc agcgtcaaag cttacgaatg ctgggcgtcc
     6541 aacagttgct tctacagctt cttttactgt tacgatgttt tgtgattttt cacgaactga
     6601 gatcacttga cccacttcta cgtggtatga agggatatca acgcgtttgc catcaactaa
     6661 aatgtgacca tggttaacta attgacgtgc ttgacgacga gtcgttgcaa gtcctaaacg
     6721 gtaaacaaca ttgtctaaac gttgttctag taagatcatg aagttaacac catgtttacc
     6781 ttctttgatt ttgctagctt ttacgaacaa gttacggaat tgacgttcgt tcattccgta
     6841 catgtgacga agtttttgtt tttcagttaa ttgcatgccg tattctgatt gtttgccacg
     6901 gctattaggt ccatgttgac ctggtgcgta agggcgacgt gctaattctt ttcctgtgcc
     6961 tgacaatgag atgcctaagc gacgagaaat tttccatgat ggtcctgtat aacgagacat
     7021 taaaatttcc tccaatgaat ataagttttt ggagtaaaat aatccgttga aaaattcata
     7081 atcatatagt ttgttcttca atcttcacct ttgcagccgc ggttacacaa tcgaacccga
     7141 gacggggcaa caaactaggg atgagttatt atttttctgc tgcattattt tacacaaatt
     7201 acagtatatg atagatcatc cacgaatgtc aagataatta gtacataaaa acgctttaca
     7261 aacctaggct gtctttataa aatgagaggg tatgtgcaaa tggaaaaaag cgaaggaagt
     7321 ttaaggagaa aatcaatgaa tccggtatca ccattatttg agaaaatcga tgcttcaatt
     7381 gaaaagaagg cgaatctttt tgaaaacagc ttttcacgtt acgctgttcg agcggttctc
     7441 gcctgtttgt ttttgacttt aggaacggct gtggcatttg cgatcgcgat gaagggggaa
     7501 gatatcgcgc atggtctagg aaagatttta tacgcattta tgttcagctg gggtctggtc
     7561 atgattctat acatgaacgc cgaattagga acatcgaata tgctttatat gaccgtgggt
     7621 gtttttcggc agagacttgc tttaagtaag gcagccaaga ttctatttgc ctgtattttt
     7681 ttcaatatga ttggcggtat attatgtgga tttctaattt ctatgactac gccatttcaa
     7741 gatttaacgt tggacaactt tatgttagaa tcaatagcag taaaactagc aaaaccttca
     7801 gcaacgattt tggtggaagg gatgtttgcg aatatcgttg tcaataccgc tgtactgatc
     7861 agcatgcgga tgaaagagga tgtcggaaaa gtgatcacag tcgtattcat cattttcatt
     7921 tttgcttttt taggatatga acacgtgata gcgaattttc ctgcctttac gcttacttac
     7981 tttgcttctc acggacagat ggatggaatg acagtcagca atgtgttaca taatttgttt
     8041 tttgctttgg caggaaatta tattggtggc ggtttagtaa tgggactggg atatgcttgg
     8101 ctgaatcagt caaaatcatc ctatgtggac taaaaagtcg ttcattaaag gggaagtgcc
     8161 atggaagttt tagtttttcc aaaaaatgag gaaaaagcgt tacaaatgga aaagtacatg
     8221 aaaaatcttt tttcctttgc tggagtacct aagccggaac gcgctctttt acaacaaccg
     8281 ttactggatg agagcaaaaa tttatctatt tctgaagttt tagcttttgt tcattattat
     8341 tatgaacaaa tcgaaagaga gtatcagtat gtagcgatcg atttagtcca gaaaaacatc
     8401 aaacggctta catttgaaga cttagtcgta ttgttgccac tagttcagaa aaaagaatgg
     8461 tgggacagca tcgactcttg gagaaaagta tacagcacat ggtgtaaagc ctacccagag
     8521 cagcgtgaag aagtctttca attgtttgaa aaaaaggaag atttttggct acgtcgaata
     8581 gcaatcacgt tgcaattagg ttataaacag caaacagaca caggactatt gatccgagca
     8641 atagacgaag atcgtcaaac aaaggaattc tttatccaaa aagcaattgg ttgggcatta
     8701 cgcgattata gtaagaccga tgccgattgg gtaaaaagac agctgacaac agatttgagt
     8761 aagttagctg ttcgagaggc aagtaagtat ttataagaaa gcgagacgac aagagatgag
     8821 acgcaaatta tttgcttttg atattgatgg aacgttgtta gattcaaaca aacaagcttt
     8881 agatagcaca agagaagcat tggaaaaatt acgcaaagcc ggtcatctgg tcacgattgc
     8941 tacagggcgg agccgatttc atgcgcaaga gatcattcgc gatcttgatt ttacgaacta
     9001 cattttatgt aatggagcgg ccggtttttt agaccatgaa caagtatata agaatttact
     9061 agatcgcgac cagttggatg cgttcgttca agaagcgcat catgagcaga tcgatacagc
     9121 ttttgtcagc ttagacaata tcaagcgttc ttcttccaat gatgtaacgg tgatggaaga
     9181 agcgatgcat tctttcggtg ctgtcttgcc tgaattagat cagttttttg cagaggaaca
     9241 agaaatatac caagcgttag catttttcga tcaaacatat gatgggaagt tctcttcata
     9301 tgataaaatt cgatttgtcc gctggcatga gaacagtgta gatgtcgtac ctaaaaatgg
     9361 ttctaaagca gcgacaattc tgcacttagc agaacaagta ggcatccctc atgaagacat
     9421 catcagcttt ggcgatggac aaaacgaccg tgaaatgttg cgcatgtcag gaattgggat
     9481 agctatgggg aatgctgtgc cagaagtaca agcagaagct aagatggtca ctgatacaaa
     9541 cgatcaggat ggaatttgga aggcattgaa agagttaagc gtgatttaaa agaggttgtg
     9601 aaaaagctgt tctgcatcaa gtaataagcc cagccaaaca aaaatagctc ctcctatttt
     9661 tcgtttttct gggcttatta ccgcagatgc aagctttcga acaccgttta aggaagaggt
     9721 cgtgacagaa gtggtcagtt tcaagaaata agaagggatt tacgaaaatt gcttctcaaa
     9781 tttttgtaaa attacggctt atttctgaag aagtagatga aacaacgttt attcgggaaa
     9841 tgggactgtg acaagatgtt tgtcatagtc ccattttttt attttatttt tcaaaactaa
     9901 gaaataccag gaaagagttc cttttgtttg accttttctt tcttattgaa aacaactata
     9961 atatagagtg atgttaaaag agaagaggaa tttagtgtgc gggtattgtt tattggtgat
    10021 gtagtaggtt caatgggacg agagatgatt actgaatatc ttcctagatt gaagaagaag
    10081 taccgtccgc aagtaacgat tgtaaatggt gagaatgccg cttctggacg tggaatcaca
    10141 gaaaaaatct ataaaaaatt tttgcaagac ggcgtagatg tcgtgacgat ggggaatcat
    10201 acgtgggaca accgcggaat ctttgagttt gtaaatgaag ctaaaaagat ggttcgtccg
    10261 gcaaattttc cggaagggac gcctggacaa gggatggtct ttgtcaaagt gaaccaagtc
    10321 gaactggcag tgatcaacat gcaggctcgt tcttttatgg tggacttgga tgatcctttt
    10381 cgtaaaatga atgagctggt agaagaagcc agaaaacgta cgccgatcat ttttgtagat
    10441 tttcatggag aaacaacaag tgaaaaacaa gcaatgggct ggtttttaga tgggaaagtt
    10501 tcagcagtgg tcggtacaca tacacacgtt cagacaaatg atgcgcgaat tttgccaaga
    10561 ggaacagcgt atctgacaga cgttgggatg acaggtccct atgatggtat tttgggtatg
    10621 cgcagagaac ctgtaatcga aaagtttctg actgcattac caaaacgttt tgaagttgtg
    10681 gaacaaggcc gatcgatttt aagcggctgt atcttggaat tggatgatac gacaggtcat
    10741 gcaaaagaaa tccagctgat tcagatcaac gatgatcgac cgttcatgga gtagaaagag
    10801 aggcagtttt ttgcagcagg agccggaaat tcaaaaagaa gtaaggaaac tgacaaaact
    10861 tttaagagag aatgaaacga tcattcgcta caaagaactt gaagaaaaga tccagcaaaa
    10921 ccagtattta gctgagttga gagaaaaaat caaacaagcg caaaaagatg ctgttcattt
    10981 tgcccactat gacaaaccag cagcagaaaa agaagcaatc aaacaagcgg atcaattcat
    11041 gcaagaattt gatcagcatc cgcttgttgt agcttataga aaacagctgt tggaagcaga
    11101 tgatctgctt catcatttaa caactatgat acaagaagaa atcaatggac aaatagagga
    11161 ggaaaaacat gcctcaaaaa actaaaaata ctcctatgat ggaacaatat ctaagcatca
    11221 aggcccaata ccaagatgct tttttgttct atcgtttagg agacttttat gaactatttt
    11281 acgaagatgc gatcaaagcg tcacagcttt tggaattaac gttgacgagc agaaatcgaa
    11341 atgcagaaga acctattcct atgtgcggtg tacctcacca tgcagcacaa ggatatatcg
    11401 atgccttgat tgaaaaaggc tataaagtag cgatttgcga gcaggtagaa gatccaaaga
    11461 cgactaaagg gatggtcaag cgcgaagtga tccagctagt cactcctggt acagtcatgg
    11521 acagcaaagg attgtcggca aaagacaaca attttttaac agctgtagtt agtcaaggaa
    11581 atgaatttgg ctttgcttat gccgatttaa gtacgggaga attgaagacg gctcggttgc
    11641 atgatgaaga agctgtttta aatgaagcct ctgcattgca gacaaaagaa ctcgtattag
    11701 gcagtgagat cactgatacc cttcgtgaac agctaagcgg gcgtttaggg ctagtctttt
    11761 ctcaacaaaa tgagatggaa gaaaacgcgg aatttagctt tttgacaagc gaactagtcg
    11821 atccgctgga aaaagaagca accggcaaac tattgactta tttatcggtg acacaaaagc
    11881 ggagtttagc tcatatccaa aaagcagtag aataccaacc agatcatttt ttgaaaatgg
    11941 attattattc aaaattcaac ctagaattaa gccaatctat tcggactggg aaaaagcacg
    12001 gcactcttct atggttgtta gatgaaacaa aaacagcaat gggtggccgt ttactaaaac
    12061 aatggctaga ccgtccgctt atccaggcaa aacaaattaa agcaagacaa gaaatggtcg
    12121 cttctttgct agacagctat tttgaacgta tcgatttgca gtcagcatta acgaaagtct
    12181 atgatctgga acgcctagca ggtcgagtag ctttcggtaa tgtcaatggg cgagacttga
    12241 tccagctgaa aacttcttta gaacaagtgc caatgatcag agggttgatt gaaggaatcg
    12301 atcaaggtca atggcaaagt ctgctttcag aaatgcagcc gatggaccat ctcgtccaat
    12361 tgatcgacca agctatccaa gatgatccgc cgttacaaat aacggaagga aacatcatca
    12421 aagatggatt caatgagcag ctcgatatgt accgttctgc tatgagaaac ggaaagaaat
    12481 ggttggcaga acttgaagca aaagagcgtc aagaaacagg aatcaagaac ttaaaaatcg
    12541 gatttaaccg cgttttcggt tattatatag aaattacaaa agcaaatctt ggaaatgcag
    12601 aactggagaa gtatgaacga aaacaaactt tagcaaatgc agagcgtttc atcacaccag
    12661 aactaaaaga attggagaca caaatcctcg aagcagaaga aaaatctgtt gatttagaat
    12721 atcagttgtt tttagctgtg agagaagaag tcaaaaaggc tatccagccg ctacaagtac
    12781 ttgcaaaagc aatcagttca gtagatgtgc tacaaagttt tgcaacgatc agcgaacgct
    12841 atcagtatgt tcggccagaa cttgtcagtg acaagcatca gcttctgatc aaagacggac
    12901 gacatcctgt agtagaaaaa gtattaggac atcaggaata tatccctaac agcgtagaaa
    12961 tggcagaaga cgaaatgatc ttgctgatta caggaccgaa tatgtctggt aaaagtacgt
    13021 atatgcgaca gttggcatta actgttctga tggcgcaaat gggctgtttc gttccggcaa
    13081 aacaagcagt tttacctatt tttgatcgga tttttacccg aattggtgca agtgacgact
    13141 taattgctgg acaaagtact tttatggtag agatgatgga agccaatcaa gccctgcgtt
    13201 atgctacgcc aaacagtttg attttgtttg acgaactagg gcgaggaaca gcaacctatg
    13261 acggaatggc gttggcccaa gcaatcatcg aatatatcca tcgtcatgta caagcaaaaa
    13321 cactcttttc tactcattat catgaactga cggtacttga gaaagaactt ccgcagctta
    13381 aaaatgtcca tgttggagcc gttgaaaaag acggagaagt tgtcttcttg cataaaatga
    13441 tggatggacc tgcggataaa agctacggca tacatgtggc aaagatcgca ggattgcctt
    13501 ccaatctact agaacgagca gcagatatcc tgcatacgct agaaaatggc gataacggac
    13561 accatactgt tccagctgaa gtagaagaga aaactaaaac agccaaacag gagcaaataa
    13621 aaccacctgc agaaaaagta aatcaagacc atatacaaga ccgtgtaaaa gaagaaaacc
    13681 aacagctttc tttattcagt gaattatccg aaaatgaaac agaagtcatt gaatcactga
    13741 agcaaataaa tttactagaa atgacgccaa tggatgcact aaacacatta tatgaattac
    13801 aaaaacaact gtaggaagaa ggcggatatc gatggccaaa atccaagaat tatctgaacg
    13861 tttagctaat cagatcgctg cgggagaagt agtggagcga ccagcttccg ttgtgaaaga
    13921 attagtggaa aatgcaattg acgccggcag tactcagatt gatatcttag ttgaagaagc
    13981 gggactgcgg acgatccaag tgattgataa cggagaaggc attttggcag acgacgtaga
    14041 gaatgccttc aagcggcatg cgacaagtaa gatccataat cgcgacgatc tttttcgcat
    14101 acgaacgctg ggctttcgag gggaagcttt gccaagtatt gcctctgttt ctgaaatgac
    14161 tctggaaacg gcgaatcagg aagaaaaaca aggcacctat ctgtcgctga aaggcggaga
    14221 agttattgag catcgaccag caccactgcg tcaaggaacg aagattaccg tcagcaatct
    14281 gtttttcaat acgccagccc gcttgaaata cgtgaaaaca ctgcacacag aattagcgaa
    14341 catcggggac atcgtcaatc gactggcatt gagtcatcca tcgattgctt ttcgtttagt
    14401 acatgatgga aacaaaatgc tggcaactgc tggaaatggc gatctgaaac aaacaattgc
    14461 gggaatctac ggattatcta ccgcaaaaaa aatgctgaaa atcgaaggaa aagatctaga
    14521 ttttgagtta tttggctatg tttcattgcc tgaggtgact cgtgccagta ggaattactt
    14581 atcgacgatc atcaatggac gttttatcaa gaacttttcc ttgaataaag caatcgttgc
    14641 aggttatggg tcaaaattaa tggtcggtcg tttccctatt gctgtattgg aaatcaaaat
    14701 ggacccgctt ttagtagatg taaatgttca tccgacgaag caggaagtcc ggctgtcgaa
    14761 ggaaaaagaa ctaacagagc taattagtaa cgccattcaa aaagcattgt ctcaagaaaa
    14821 tctgattcca agtgcagcgg ataatctacg gtttaagaaa aaagtacctg atcagcctaa
    14881 aacagaacaa atcgaaatcg atttgtccta cgcttttgaa gaagaaaaac ctaaaaagcc
    14941 aagtagtttg aattttgatc gagagacagg tacctttttc gtagaagaac taaagaacac
    15001 atttgttgac agaattgttg ataagtctgt ggaaaatgtt gaaaactatt ctggtttttc
    15061 tgaagaaaac accacttatc cagaaaaaac agcgaaaacg gtggataagt ttggtgaaaa
    15121 tgttgataac tttgtagaaa aaacagtgga aaaatctgaa aagaaagaat ttcccattgt
    15181 ggataacatg gagaaaacaa atgaagaaca agcagataaa tccgtagaag aggatgaaaa
    15241 gatttacgag gaagaattga cactccatcc tgaatttgat ttcactcaag gaaacgacaa
    15301 aacattagaa caagccatca agaaattaga aacggaaaaa ccagtacaac gttttcctca
    15361 gttggaatat tttggacaga tgcacggaac gtatcttttt gcccaaagta gcgatgggtt
    15421 gtacatcatt gatcagcatg ctgcccaaga gcgcattaag tatgaatatt tccgggaaaa
    15481 aattggggaa gtatctgatg atctgcaaga attgcttgtt ccatttgtgt tagactatcc
    15541 aaacagtgat gctttgaaat taaaagagca aaaacacttg ctagaagatg cagggattta
    15601 tttagaagaa tttggtcaaa acagctttat tgtacgggcc catcctactt ggtatcccaa
    15661 tggagaagaa gaatcgatta ttcgggagat gatcgatatg ctgctgacaa ctggaagtgt
    15721 gagtgtaaaa aaattccgtg aagcaacagc aatcatgatg agttgcaaac gatcgattaa
    15781 agccaaccat tatttgaatg aagcacaagc acgtgtgctg ctgaaggatc tggcacgatg
    15841 cgaaaatcct ttcaattgtc cccatggccg tccagtattg attcacttta ccaattcgga
    15901 tatggaaagg atgttcaaac gaatccaaga cccgcattaa gtcaaagaga agagggaaaa
    15961 catgaagatt gtattagcat cccaatcacc aagaagaaaa gagttattgg ctcatatcgt
    16021 ttcagaattc gagattgaac ctgctgatat cgatgaaacg ccatttccag acgaacagcc
    16081 cgtcgattat gttcgtagaa tggctgaaga aaaagcacga actgtctggg aacaagatga
    16141 aaaagaagac catttagtga ttgccagtga cacgactgtt gttctcaatc aagagatcat
    16201 gggtaaacca gaagatctgg ctgaggctga attcatgctg aaaaaactaa gcggggaaac
    16261 acatactgta tatacagctg ttgttttaaa aacaaaggaa cgagaagaac ggatactagc
    16321 agaagcacat gtcacttttt atcctttgac agacgaagag atcaaacgct acttggagac
    16381 gggggattat gcggataagg caggggcata cggcatccaa aatgctgcga gtgtattcgt
    16441 caaagaaatt tctggagatt attacagtat cgtaggattt ccgattggtg ctgtcaatca
    16501 ggcactgaaa acattcattt aaacaaaaaa gcggactatc tgattttcga ttgaaaatcc
    16561 atgatagccc gtttttttta ttgaaaagat tacttatcta ctctgactaa gattttactt
    16621 cagctttacc gactgcttcg cccgggcgaa caagtcctga ttggtcaaga gaaagtcctg
    16681 caactttttc attattggtc aaagcaacaa taatgtcagt tttcttgcca gcttgttcta
    16741 tttctggcaa atccatttca gcaatcaggg tctctggtgt gacaaggtat ccttctttca
    16801 cgaatacatt gaaaggaaca ccctttagtt caacagtatc taatcccatg tgaacaagta
    16861 cttccagccc ctcattagaa agaataccaa tggcatgttt tgtttcaaag acactcgtca
    16921 ctttaccgtt tactggtgca tagactttgc cgtttgacgg ttcgacagca taaccgtcac
    16981 ccatcatttt ttgtgagaaa actgggtcat ttacttcagt tatttccttg atggtccctg
    17041 cagcgactgc gaataatgtt tcttttgttg caactgccgt accagttgct gaaacaggtt
    17101 cgaaagactg tggcgttgct gttgcgccat ttgctgtttg aagttgtaca tcagcagcat
    17161 tttcaggaac agcaggatca atcttattca aaattccctg acgtctaaag atgatcgtca
    17221 agccaaatgg aatgatgaca gcaatgatca ttgcgatgat gaaaggtacc catgtttctg
    17281 cttggatagc tagtattcct ggcaaaccgc ctactccgat cgcgttagct cgaacaccca
    17341 tcaagttagc aaacatgcca gctaatccag agccgaccat tgcagcgacg aaaggataga
    17401 cgtatttcaa attgattccg aacatagcag gttcagttac gcctaagtaa caagaaatca
    17461 ttgctggaat cgagatttgt tcttcttttt tattcccacg atgtaagaag atgatggcta
    17521 agactgcaga gccttgggcg atatttgata aagcaatcat cggccataaa ttcgttgatc
    17581 cgaaatctgc aatcagctgc atatcgatgg cattggtcat atggtggaga ccagtaatca
    17641 ctaaaggagc atacaggaat ccgaatacgg cactaaacaa ccagctgata gaagacgtca
    17701 atccagtatt tacgatattt gagatccagc ttccgactgt ccagccgata ggacctaaaa
    17761 taacgtgtgc agctaaaaca gttggtaaca atgaaaacaa tggaacaaaa atcatcgaga
    17821 tcgactgagg gatatatttg cggaagaaga tttctagata cgctaacata aaccctgcca
    17881 gcatggctgg aataacttgc gcttgataac caatcatctg gacttgagca aaaccaaaat
    17941 cccaaaatgg aatatctgct gcggctgtgg aagctacact ataagcattt aataattgcg
    18001 gagaaactaa cgtaattcct aaaacgattc ctaatatttg tgtagtaccc atcttttttg
    18061 caatactcca agtgatacct actggaagaa aatggaaaat tgcttcaccc ggtaaccaca
    18121 aaaaggcatt gacaccattc caaaacttcg agtgttcaac gattgttcca ccaagacttt
    18181 caaactggat accttcaagt acatttctga atccaaggat caatccaccg acaatgattg
    18241 caggaatcag tggtgtaaag atttctgcta aaacggcaat agcacgttga acgggatgaa
    18301 ggttttgttt tgcagctgct tttccttgtt ctttggaaac cccttcaact ccagatactg
    18361 caacgaagtc gttataaaaa gtagaaacat cgtttcctat gatgacttgg aactgtcctg
    18421 cattcgtgaa catccctttt acgctaggta tatcttcgat cgctttttcg tccgcttttc
    18481 ctggatcatt caggacaaaa cgcatacgag tcgcacaatg actaactgca gcaatatttt
    18541 cttttccgcc gatatcatgt aacagcttct cggcatctgc ttgatatttt gccatatcaa
    18601 taaacccctt tctcttaact tgtctatgca agttgtttct tcatttacta tacttttttt
    18661 cggagagaat tgcaagcgtt ttattaaaaa gtacgagaga aaatgatatc gttttaaaaa
    18721 gcttaaaata agcttttctt aaaaatagga acattgaaat acaaaaagag ctgtagtata
    18781 gtgaagaaat gatggaagaa cgagtgaggg aaaaaacatg aataagttca atgaaatttt
    18841 tttagatttg gaacagaaaa ttttagcgaa agaatatcct ccgcattcgc ttttacccag
    18901 tgagaaccaa ttgatcaaaa tttatggtgt ttcacgagaa acaattagaa aagcgctgaa
    18961 tcttttgact acggaaggtt atattcaaaa aaaacaagga aaaggttcga tcgtactgga
    19021 tcggaatcgc ttcgactttc ctatttctgg attgactagc tataaagagc tacaggagac
    19081 ccaacgtatt ccaagtgaaa cgatcatcca tacgttagaa gaaacagaag tgacaaaagc
    19141 attgaacgag atcactggct gggagatcgg tgcgcctgtt tggcatttga tacgcgaaag
    19201 aaaaatcaat ggcgaagtag ttatattaga caccgattat ctattaaagg aaatcgttcc
    19261 tattttaact ccagcacaag cacaaggatc gatctatgaa tattttgaaa atgagctttc
    19321 tttgacgatt gcttacgcgc aaaaggagat cacagtagaa gaagtaacgg aaatcatgaa
    19381 aacagcgatg gatcttcacg atgacactta tgcagtagta gtcagaagcc tcgttcatct
    19441 ggaagatacc cgctgtttcg agtattctga gtcggttcac cgattagata aattccgttt
    19501 cgttgagttt gcccgacgcc gaaaagtgta aatagttcaa aagaaagcaa attgttggca
    19561 tctgtccact ttggcgctat gataggatca caaagggggc atttttaatg gataaaccaa
    19621 taagaccaga aaaagaagaa ctgaaagaaa agttatcacc catggcttat gcagtcacac
    19681 aagaaaatgc aacagaacaa ccatttagcg ggaaatatga tgatttttac gaaaagggga
    19741 tctatgtaga tatcgtcagc ggtgaaccgt tattcagctc tgcagaaaaa tatgatgcag
    19801 gttgtggctg gccatcattc agcaaaccaa taacgaaaag acaagtgcgc gaaaaagccg
    19861 atttttctca tggcatgcat cgaatagaag ttcgaagcaa agaagcagat tctcatctcg
    19921 gacatgtgtt taccgatgga ccagtagatc aaggtggtct acgttactgc atcaattctg
    19981 cctcactgaa attcattcca tatgaaaaga tggatgaatt aggttatggg gaattcaaat
    20041 cacttgtaga ataatggaaa tacacaaaga gcggtacaat acggggattt actcgatcgt
    20101 ccgctctttt tttattcaag cgattgctat ttgaaagaaa cgctccctag actccttttt
    20161 tcacaaggtg aaatgtgcta caataaaggg aacgtatgtg tgcaaaagaa agaggactag
    20221 aatatgtatg aatatctgac aggtgtggtt acctttatca acccctatta catagtagta
    20281 gaaaccaatg gtatcggcta ccagatcgca ctaggaaatc cttaccgcta cagtagcaaa
    20341 ctaaatgaaa aaataaaaat ttatgtccat caggtaatac gtgaagatgc gcatcttctg
    20401 tatggatttg attcgctaga agaaaagcaa ctgtttttgc gattagtaag tgtttcagga
    20461 atcggtccga aaagtgccct tgcaatcatg gcaagcgaag accactccgg tttgattcaa
    20521 gcagtagaat ccagtgatgt cacttatttg acgaaatttc caggagtagg gaaaaagaca
    20581 gcacaacaaa tgatcttgga tctaaaagga aaattcggtg agctgagtat cgatacacct
    20641 tttagtctat ttgatgaagc aaacacaaaa gacgctacag ctctatctga agcaatggaa
    20701 gctctctcgg ctcttggtta cagtgatcga gaaatcaaac gtgtagaaaa acaattaaaa
    20761 gaagtagata atcagacaac ggatgagtat ctacgccaag cactcaagct aatgatgaaa
    20821 aaataaggag gagaccaaat gacagatgaa tacttgttat caccagaatc tggcgaaaat
    20881 gaactgagtt tggaaaaatc tcttcgacca cagctgcttt ctcaatatat cggacagaga
    20941 aaagtcaaac aagaacttca gatttacatc gaagctgcca gaaatcggga agaaccttta
    21001 gatcatgttc tgttgtacgg gcctcctgga ttaggaaaaa cgacgatggc catggtcatt
    21061 gctaatgaga tgaccgtaaa tattcgtacg acgagtggcc ctgctatcga acgtccgggt
    21121 gacttagtag caatcttgaa tgaactggaa gcaggggatg tcctgtttat cgatgagatc
    21181 catcgattac ctagagtggt agaagagatg ctttattcag ctatggaaga tttctatgta
    21241 gatatcatgg taggacaagg gccaaccgca catccggttc atttccctct tcctcccttt
    21301 actttgattg gcgcgacgac acgggcaggt atgctttctg cacctttacg agatcgattt
    21361 ggcatcattt ctcatatgga atattatgac gaacaggatc tgcaggagat cgttttacgt
    21421 tcttcggata tttttcaaac agagatcatt gaagaagggg cattggaaat tgctcgccga
    21481 tcacgaggaa cgcctagaat cgctaatcgc ttgctcaaac gggttcgtga ttttgcgcaa
    21541 gtccaaggag acgggaaaat cgatcgtcct atagcggatc aggcacttac tttgctacag
    21601 gtcgatcagg ctggattgga ttatgttgac cagaaattgt tgcgaacaat gatcgagtta
    21661 tatggcggcg gaccagtagg gttaagtacg ctttcagtaa acataggaga agagcgtgag
    21721 acggtagaag atatgtatga accgtatctg atccaaaaag gatttttaaa gcgtacacct
    21781 agagggcgaa ttgctactgc ttatgcctat gaacattttg gttacgacta tcatatatga
    21841 tttttgcttt tagattggag gaaaatgaat gagtgataca acacgtacga aacaattgat
    21901 caaaaacgta ttgattgatt tgtgccaaac gcaatctttt cgaaaaatca gcgtccaaaa
    21961 aatcgcaaat gaagcaaaaa tcaatcgaca aacattttat tatcatttta cagataaata
    22021 cgatttgctt cgttgggtct attgtgagga tgcattgcat tatttagatc cacaatgtct
    22081 ttcacttgat aattgggaag agcaagcatt gaaaatgctg aaagcaattg ctgagaagaa
    22141 agaattttat gcaaatactg tgctttctga cccagaaatt ttacaaaaag agttttctca
    22201 actgatccaa aaatcattta tcaagatttt tgaacaaatg gatgaagaaa gacaactttc
    22261 tgcaagagac aaactatttt atgctcgttt tttttcttac ggttgcagtg gtgtattagt
    22321 caattggatc acgaatgaat atgaagaaac accgatggaa atcgctatgc agcttttccg
    22381 tttagccaag gatacggaat tatattctta tcgtctttat gcaaaagaag agttggaaga
    22441 acagtaatag aaaaattttt tgttggaaaa gcaataatcg ctaaaaggag atggggaaat
    22501 gacaaaaatt ttatttgttt gtttgggaaa tatttgccgt tcaccgatgg cagaaggctt
    22561 gctgagaaaa cgaatagcaa tagaaggaag ggaagcagaa ttttttgtgg attctgctgc
    22621 tacaagcacg tatgaagttg gaaagacacc gcaccctgga acgaaaaaaa tattaaacca
    22681 agaaaaagta gatatgacga atatggttgc tcggcaaatc acaccccacg attttgaaac
    22741 ttttgattgg atcattggca tggatcaaga aaatgtagaa gaactgaaac gaagagcacc
    22801 acgctcagcg caggggaaaa tccatttgtt tttaagtagc attcctggaa aagaaaaaga
    22861 aaatgttccc gacccatact ataccaataa ctttgatgag acatatcact tgatcacaga
    22921 aggcctgaat cattggtgga atatttggat tgacgaaaat aaaataacaa acaatttgta
    22981 aagttgacgc tttcttttta aggcgatgtt agagcatttc cttgtttttt tgtaaaatgt
    23041 taggtaaaat aaaattaatt aagtaacact ttcttagcta aaggaggagt gcattcgatg
    23101 aacgaagaga cagtatcgcc aatgaagaag cttacgaagt tagttactca tacttcgtat
    23161 caactttttg attcttttgt aaatgacact gaagaacatg ctaagaatgt acgattgcaa
    23221 ggaaaattta ttcttgagct gcaaaaagct gctactgaac atagtctagt tatcttacaa
    23281 gtaagagcga atcgtttgag tagcaagtat gaaacgatct caggctgggt ggcgacaaaa
    23341 acggtcgaaa aagaccgagt gatgatccgc ctacaaaacg aagagcagca gatccggatg
    23401 gttcctgtag aacaaattga aaaaataaca atcctttcac cagcagggga acaggaacga
    23461 ttatcaaaat aatttatacc agatagaaaa gcacgtatga gcttgtacca tcaatcatta
    23521 ctaatcaaaa ataaccgaat gctttaagct gatatcagta aaacggaacg ttttaggatg
    23581 agtatcacag catgacagca ttgggttgat tagttgaatc gattggatgg tacaagtttt
    23641 tttgataaaa aaaggtcctg ctagccgggg agctagcagg ataaggagtt aaaaatgaaa
    23701 aagtgttgtt agggttgttt gttggtatgc ttatataata gtcactagtt gtgaatattt
    23761 tgtgacgaaa gttttcgaaa gttgttaagt ttttttgcga aaactatttt tatatcatat
    23821 atatgtctaa aatctatatt ataaaagaaa tgttgtttga tcagcttctc ttcggtatta
    23881 gttcaaaaca aaacggcaaa gtatatggag ctactttgcc gttttgtttc tctaatactc
    23941 aggtcagttt atagacgctc aataaacggt gttcaaaagc cagtttctcg gtattaagtc
    24001 aaatttatgc aaaaatgtga gaagccattt tcaaaaaata tttcttaata ctcgaaactg
    24061 agcggctttt tcacgacctc tcaataaaca gtgttcaaga gacagcctat cggcaataag
    24121 gctgaacgtc tctttcacaa cctcttttat caatctgcta cttcttcttt cttagcgaaa
    24181 ctccaaatca gtccgataac aaaaccgata actgctggta cgatccaccc catccccaat
    24241 ttgaaaaacg gcaagtagct ttccgcaaca tataaaagat tttgaacaat aggtgtttgt
    24301 ttgatagttt ctgggcaagc gttcaaccca tcaaaaatcg aagcaatcaa tgtaaaataa
    24361 gtagtcattc gataaacagc cgtacgctgc ttaaacaaag gaccaactaa cactagtaaa
    24421 atcagtgtca ttgctaatgg atagatgaac atcaaaacag gcaacgaaaa ttgaatgata
    24481 ttcgtcaagc ctacgtttgc cgctaaacaa ggaaggatac tagcaagtgc aacaaagaat
    24541 gcgtaatttc tttgcggaaa caaatctgtg aatgtttctg caaaagctgt aatcaaacca
    24601 ataccggtct tcaagcaagc taatataacg ataaatgcta ataagatact gccataagta
    24661 cctaaataat gatcagcaat ctgagccagc gtgatcccgc cattttcact tagagcaaag
    24721 ctacctaagc tcatagcacc taaataagcg agcaaagtat aaatgattcc catcaatata
    24781 atgctgatcg caccagattt gatcgtgtct ttagcgattt cagcaggttt tgttacaccc
    24841 atgttttgga ttgttgtgac aatgatgatc ccaaatgcta aagcagcaag cgcatctaat
    24901 gtgttatatc cttgagtaaa ccctgtgaaa aaagcatgct cttgataatt tggctgaata
    24961 ggcgcttgat ttacagaacc tagtggattc aaaaaagcaa ggagaagcaa agcacctaat
    25021 aaaaccaaaa atgcaggatt caggaacttt ccaacataat ctaatatctt tgtcggtttt
    25081 cttgaaaacc accaagccag cacaaaaaat acaatactga aaattgctag atatagcgtc
    25141 tgtctgctag gatcgataaa tggtgctaaa ccaatctcga aagatgtggt tgcaaggcga
    25201 ggtaaagcaa aaaacggtcc gataactaag taaagcaaga tggtaaaaac catcgcatat
    25261 gtttgattta tccgttttgc taattcatat acacctgagc ttttcgatac accaatggca
    25321 atcaccccta agaagggaag accgataccg gtaaccaaga aacctagatt cgcccaaaag
    25381 gtagcagcgc ctgcttcttg acccaaatga acgggaaaga taagatttcc agcaccaaaa
    25441 aatagaccga aaagcatgga gcctataaaa agatagtctt taaatgataa tttttttgtc
    25501 atacataact cctttacggt ttttttaaaa gtaacaaaat ttcgaaaaat atgcaacaat
    25561 tttcagaaaa tttcctatat aaaacgacgg ttatttaata acgtaagtga taaaataaaa
    25621 gcgctgaatc atctgaggag gaatcatcgt gacaaagtcg agattagaag catttactga
    25681 tggagtggta gccattgttt tgagagttct tgtattagag atcaagatcc ctaatacatc
    25741 tagctttcat tctttatggg tcatccgaaa tacattatta gcttatacca tcagctttat
    25801 atttgttgcg gtgatctggg tgaaccatca tcgtatattt cagatggcag aacgaattaa
    25861 ttaccgagtg gtctggtcga atatcttttt gctcttttgg ctgactttat gtccttctgt
    25921 tactagttgg gtcgggcgta accctgaagc tttttggcct gagatggctt atgtcttagt
    25981 atacacgatg tggagttttt cttttggtat cttgatgagg caaatcatga aagcaaataa
    26041 accagattcc catgtcgtga gagttttgtc aaaggaccgt cgaagtctta tctccatgat
    26101 gattaactta tgcttgattg ccggtgtctt ttttgtaccg ttgatcgggt tattcggacg
    26161 tttttttgta tctggtattt ggattttttc ctataaaaaa gcagatgcct attatcagcg
    26221 gttgtttccg gggaaataga aaagaggctg ggacagaagc ttttaactcc aagaaataag
    26281 ccgaaatttc acaaaaattt aagaagcaat tttcgtaaat tccttcttat ttctcgaagc
    26341 tgaccacttc tgtcacaact actttcttac ttcttacgtt catatttcat atgatagatt
    26401 agtaatagaa gcaagaacca cacaggtgtt agtaataaag cgattctcgt atcttttcct
    26461 aggaacaaga cgacacacac aaaggccatg taaagaaata ccagataatt actaaatggg
    26521 tacaacggca ttttaaatga atgagctttt ttgccgagga tacttttacg atatttcatg
    26581 tgcgtgtaga caagcatact ccagataaac aagaaacaag tagtggcaat actgcttact
    26641 agtgtgaata cttcactagg catcacgtaa ttcaagataa cagaaatgaa aatgacgata
    26701 gtagaaaatg tcaaagcatt ccctggcaca tgatgtgttg ttaacttttt gaatttttta
    26761 ggggcactgc cttcttgcgc taaagaacga agcatacgtc ctgtactata tattgcactg
    26821 ttgcaggcag aagctgctgc acttaatacg actaaattga tcaaggaagc agcaatcgtg
    26881 atcccaattt ccgaaaatac ttctacaaat ggactgttat ctggattcaa gctgttccat
    26941 ggatagattg ccataatgac aaaaagagat cctaagtaaa ataagatgat cctgatagga
    27001 atattattga tagcttccgg caacactttt tcaggatttt ctgtttctcc agcgactaat
    27061 ccaactaatt ctatcccagc aaaagcaaag gttaccattt ggaaagctaa gataaatcct
    27121 tttgcaccag ttggaaagaa tccgccatga gaccatagat tcgtgatact ggctgtgcca
    27181 atatctgtcg tatagtgggt gaggatcata taagctccta cgaggataaa ggcaatgatc
    27241 gctacaactt tgatcaatgc aaaccaaaac tctaactcac caaacaatga gacagccacc
    27301 atattcaagc aaagaagaag acctaatgca atcagttcag gaagccactg aggaacacca
    27361 ggcgcccagt agcgtacata cattccgatg gctgttaaat cggccattgc aatcgatacc
    27421 cagcagaacc aatacgtcca gccagtgatg aaagccgctt ttttgccaag atattctgca
    27481 acaaaatcca gaaaagaatg gttattggtg tttgataaca gaagttcgcc taacgcacgc
    27541 ataatgaaaa aacagatgca tccagtaata agataggcga gcaatatcga agggccagct
    27601 agctggatag actttccgga acctaaaaac aaccccgttc caatcgctcc gccaatagaa
    27661 atcagttgga catgtctatt tttcagtcca cgctgcagtt cttgctcttc attcattttt
    27721 aaatcatcct aactaaaaaa gtttaattac ttccatatta aaagagtttt ctgaaaaaca
    27781 caactaagat tccaaaattt tcagaaattt accttttatg agtaattcat aaaaaagaac
    27841 tgcggtaaac accgcagctc tttgtcccaa tcagctattg atcctaagca tttaaaatac
    27901 gtgaaaggaa ttcttttgta cgttcttctt tcggatggac aaagatatct tctggtgtac
    27961 cttcttctgc aatcacacct ttatccataa aaatgacacg gtcagataca tcttttgcaa
    28021 attccatctc atgcgtcacg ataagcattg tcaagccagt atgtgctaag tctttgatcg
    28081 tattaagcac ttcgccaacc atttcagggt ctaacgccga agtaggttcg tcgaatagca
    28141 atacatctgg attcattgat aatgcccgag caattgcgac acgctgtttc tgtccaccag
    28201 ataattgtgc tggtttggct tcgatataac gatccatacc aactttttcc agattttcga
    28261 ttgctacttt tttggcagtt tctttatctc gtttcaggac agttgtttga ccagacatac
    28321 agttttccaa gacattcata ttgttgaaca ggttgaagga ttggaaaacc atacctagat
    28381 tcgttcgata tttaggtaaa ttatatttag gagctaatac attttctcca ttataaatga
    28441 tctcgccgcc tgttggtttt tccagtaaat tgatacagcg caagaaagta gatttaccag
    28501 aaccggaaga accgatgatc gtcacaactt cacctttatt gactgttacg ctgatatctt
    28561 tcaatacttc attttcaccg aagctttttc ttagatgttt gatttcaata attttttcat
    28621 tcatgattct tcctccttat tcctgcaaat ttgaattgtc gatttcttca agcttggtat
    28681 aagctgaagg accatcgatt ttcttttcta ccgcccgcag gattctggtg atcgtaaagg
    28741 tcatgactaa gtagatgatc ccgacgatcg taaatgtttg gaagaattgg aaattcgcac
    28801 cggaagcaga gtttccttgg aagaacaaat cagctacgcc gattacactt aaaactgctg
    28861 tatctttgat attgataaca aactcatttc ctgttgctgg caagatattc cgtaaaactt
    28921 gtggaataac aacttttctc atcgtttggc catgggtcat accaatggct tgcgcagctt
    28981 cgaactgccc ttcatctact gcaaaaatcc ccccacgaac gatctctgtc atgtaagctc
    29041 cagtattgag agagacaata aacaaagcgg caatcgttcg gttcaatgaa atgccaaaag
    29101 cgagtgccag accgtagaag atgaccattg cttgtaccat catcggtgtt ccgcggaata
    29161 cttcgacata gatagaaaga agtgcatttc cgattttttg gaagaagcga gtcagtgcat
    29221 ttcctgattc aggtaccgaa cggaagacac caatcagtaa tccaagtgta gtaccgacaa
    29281 ctgtcccgat caatgcgatg aacaaggtaa gtccagcacc tcgtaagaac atattgccgt
    29341 attgtttcca aatcgtagtg aaatcagaaa tgatgccagg tttttcttca ctatcagttg
    29401 cagcaggctg atctttgact gcttggtcca taattttggt tcgttcatcg ttagagatgc
    29461 cagaaagaat ctggtttact ttttggatat ccgggtcgcc tttacgcata ccaacagaaa
    29521 tctgaacatc ttccgggttt gtctggaagc catctgcacc gctgaattca agcatttcca
    29581 agtctttgtt cacactagtt gccgttacac cttccggacg ttcgctgaca taaccatcga
    29641 tcattccaga agctaaagct gttctcattg ctgagaaatt atccattgct tgttgtttct
    29701 gcacatctgg tatctgatcg atcacagtat agtggaatgt atttaactga gcagtaatct
    29761 ttgctccaga aagatctgct aaactttttg cttttgcata tttgctatct ttttgaacta
    29821 ctactactaa ttgtgattcg taataaggat cggtaaaatc aatttctttt cgtcgttcag
    29881 cagtagggct cattccggcg atgatcgcgt cgatcttgcc tgattgaagg gcaggagcca
    29941 gaccatccca tttcgtttgg acgatgacta attttttccc taaaccatct gctacttttt
    30001 tagcgatttg aacatcataa ccgccggcgt aactattttg gccttgaatt ggcaaggcat
    30061 tattctcatc tgtttgttga gaccagttga agggtgcata cccagcctcc atacctacgc
    30121 gaaactcatc gctcggtgtt ttttcatctg catttgccag agatcccaca ctgaatagtg
    30181 agaagacaaa agcaaatagt acggcaactg aaaccatatt ttttttcatt tttttctccc
    30241 tttctgatta tatgatacac gagcggtcta gatgaaatgc ggtaaagctt tatctgaaaa
    30301 aataaaaagc gaccgattta tagatataaa aaggccgcta aaattccata aggtgataaa
    30361 cctctcacaa aacatagcgc aacttagcat cactgctaag acagtccgca agctcttaac
    30421 ttgcgtccca acatacactc caagcaaaaa agtgcacatt tcggcgatcc tccctattcc
    30481 tgcttctcca tgtttgcttc actccacagg gttaatgatt ctcgcgacct ctacctcatt
    30541 gattgaggca tctcgtattc agttatttat acaaaaaaag tttacgatac tcgagaggct
    30601 ttgtcaatct ataactgctg ttttttgaaa aaatactgat aaatatagaa atctttactt
    30661 ttaccgaaaa aacaatcaaa atgtgaatca tctatccatt gcaaacgata gtataattat
    30721 acacaaaaat gtatgtaata caataaaaaa agaactagaa cagaaaattt cctgtgtcca
    30781 gttccatctc gatcatttaa gctgccgctt tctttggctc acgtcctagg atcgcttgca
    30841 aaagaacaac gacgccataa atggctaata ttagataaat caaacttgag tattgggtga
    30901 ttccccagcc ccatgttcga tatacggcta atgtaatggc taaaacaatt gcggcaatca
    30961 cgttgaataa agcaaaagcc caaagatttc cattttcttt gcgtacaaga taaaaaacag
    31021 agaaataaac gcttaacgct aaccaggcga tacaagccag aataacgccc caataaataa
    31081 agaatggtaa catatcgatt cacctcactt ttatacagca gtattgtaac acgttttcat
    31141 tcttttgtca gtgaacattg tgataaattg ttcaaatgcc cataacactt ttttattccc
    31201 atttttctga cttttcaaca ataaatttgt tcgagtatgg gctataatgg aaagtgaggt
    31261 gacaaaacat gaaacaatta acagtagacg aagcagcaaa agagatatta gcttatcagc
    31321 aaattacatt tttgaccggt gcaggggtat ccacaccttc tggagtgcca gactatcgat
    31381 ctttgtcagg aatctaccac gggatggagc agccggaata cttgctgagt catcaagcaa
    31441 tggtgaatga accggataaa ttctatcaat ttgtcaaaaa gatttatcat cctgaagcaa
    31501 aacccaatat cattcatttg gaaatggcac atctagcgaa agaaaaaaat gtttgggttg
    31561 tttcccaaaa catcgacggt ttgcacgcaa aggctaaaag cccgcaactc gtcaattttc
    31621 atggaagttt gtatcaatgt cattgtcgaa aatgtcaaca aacggtagac tggaaagaat
    31681 atcttcacag cgacaaacat caagcatgcg gaggacaaat acgcccagac atcgtgttat
    31741 atggtgaagg gtttcaagat ggagtcatgg agcaggcggc ttatgccgtc agccaagcag
    31801 agctgatcgt cattgttgga acgagttttc aagttcatcc gttttgtgat ctggtacagt
    31861 ttcgccagcc gtcagccaaa atcttagtaa tcaatcaaac gcctgtttat ttagcggagc
    31921 cttatacgtt tattcaagaa gacggagcgg ttgttttcaa aaaaatacaa gaattaggag
    31981 cagattatga ctgaattcaa aaccgaaaaa gaaaaaatga ttgcaggcga gctttatttt
    32041 gccaatgatc ctgagctggt tgccgaccgt atgtttgcaa gaagtcaaag ccaaatcatc
    32101 aaccaagcag aatcagcgga actgcgatcc caattgttga aagagacttt tggccgtaca
    32161 gggaaaaaaa tctatatgga gccagttatc aattttgatt acggatataa tatatttgtt
    32221 ggggagaatt tttatgcaaa tttcaattgt acatttttag atgtcagcac gattgaaatc
    32281 ggtgataact gcatgttcgc tccgaatgtc cagctttaca cggcgacgca tccactacat
    32341 ccagtgaaac gtaacagcgg tctggagtac gcaaaaccca ttaaaatcgg taataatgtt
    32401 tggttaggcg gaggagttat cgtcacgccg ggtgtcactc taggggacaa cgtagtagtc
    32461 ggcgcaggtt cggttgtgac caaatctttt cccgacaatg tagtgattgc aggaaatcct
    32521 gctcgtatca tcaagacagt agaggaagaa ctaacagaag agtctcttga aacattacgt
    32581 cataagatcg atatgatcga tcgagagttg attgctttat tagaaaaaag aatggatacg
    32641 gtaactaaaa taggacaagt gaaaaaagaa gaaaaccaag cagtttatga tgcaaaaaga
    32701 gagcagcaag tattggataa agttgttagt ctgctgaaaa ataagggata taaggaaaca
    32761 ataacagata cgtatgttga tttgatgaaa cactcgcgcg aataccaaaa caaaatgaag
    32821 gaggaataag tgtgatcgaa ggagagacac ggcgaaaaca aatcatgcaa accttggcaa
    32881 atacagaaaa accagtgagt gctagcaagt ttgcgaaaac ttttggagtc agccgtcaga
    32941 tcattgtagg cgatattgct ttactacgag ctgcaggtaa aagtatcgtg gcaacagcaa
    33001 gaggttatat cctcgaaaca gaagaaacca atactgggca catcagtaaa atcgctgtcc
    33061 agcatggaaa agatcaaaca gaagaagaac tgagactaat cgttgaaaat ggtggtgaaa
    33121 tcattgatgt aattgtggaa catccccttt acggtgagtt agcaggaact ttgcacatca
    33181 aaacgccaca agatatcgat tcctttatga gacgttatca aaaaagtaat gctactttgt
    33241 tatccgaatt aacaggcggc atccatctgc atacgatccg ctacccagaa aagcatatgc
    33301 tgaaaaacat caaacaaaaa ctagctgaag caggaatcct ctacgaagga taacatcgta
    33361 gctgctactt tttatcctag aaactattct atcatctctg agataaacac ccatatggaa
    33421 gaaataagaa aaaataagaa aagatgcgta tccaatacac agaatttttt ggaattgcga
    33481 tttctagatg tctatctaaa tttcgattag tggagaaaca taaaaaaggg aagtgcagct
    33541 tttgagcact cccctttttt ataaagcttt cttgtagcat agtatcgaag gaacctgcca
    33601 attctctact cgatcaccaa tacgccttct tttagtgcaa atggattttg atcgttgatg
    33661 tggtcataga acatcacacc gttgatatgg tcgatttcat gttgaacgac gatcgattca
    33721 taattcttca aacgaatctt gtgtttttca ccattcatat cataataaga cacagtgatt
    33781 ttggcatggc gaacaacata tcctggtact tctcgatcaa cagataaaca gccttcacct
    33841 tcccctaaac aagcatcttg aacagaatgg ctcaaaattt taggattata cataacagta
    33901 cttagagaag gtccatctgc ctctgggtca ggacttggta cgtgaacagc aatgattctt
    33961 ttagaaatat ctaattgagg agcagctaag ccaacaccgc ctcgtaagtg tagttcttca
    34021 gctttgattg gatcttggct gttttttaag aactcaagca tctcttttcc taaagagata
    34081 tcttcttcgc ttaatggaag agaaacttct tttgcaactt cgcgtaaggt cggatttcct
    34141 tcacgaatga tatcatccat tgtaatcatg gaatatgtac ccctttctta aaagactgtg
    34201 tttcaagtct attttcgcat tatagtttac cacaaaaatg gaaaagtagt agtaagattg
    34261 tttgaaaact accttttctt aatgattaac tacttgattt tcaacccggt ttcaggtaaa
    34321 gtatagctgt gtgctctagg cacatgacct gccacttggt taagcgaatc accaacgttt
    34381 tactcagtcg caggggaata atcgaaagag gtgaaagaaa tggcaatttc aaaagaacgc
    34441 aagaatgaaa tcatcaacga atacgctcgc catgaagggg atactggttc tccagaagta
    34501 caaatcgctg tattaactga agaaatcaac cacttgaatg aacatgcacg cgtgcacaaa
    34561 aaagaccatc attcataccg cggcctaatg aaaaaagttg gtcaccgccg taacttgtta
    34621 gcttacttac gtaaaactga cgttcaacgt taccgcgaat tgatcaaacg tttaggcttg
    34681 cgtcgttaat tttagtcaaa aagagtggga ttcacatgaa tctcactttt tttactcgta
    34741 tatcaattaa gtaaaattcc gtgatcaagc tagatggact cctactaacc aaatgaaagc
    34801 tgctcaaaag acggctttcg gcagttttca tttgtttagt agcgtcttgc tttcacgaga
    34861 aggaaaagga gaagttatgt cagaaaaaca agtattcaaa acgacatggg gcggccgtcc
    34921 cttacaaatc gaagtcggtc agctagcaaa acaagcaaac ggagccgttt tagtccgtta
    34981 tggagataca gtagtcttaa gtgcagctgt ggcctctaaa gaagcaaaag atacagactt
    35041 tttcccatta acgatcaatt atgaagaaaa aatgtatgca gcagggaaaa tccctggagg
    35101 tttcatcaaa cgagaaggcc gtccaagtac ggaagcaaca ttgactgccc gtttgatcga
    35161 ccgtccaatt cgcccgatgt ttgcagaagg cttccgtaat gaagtccaag taacgaacat
    35221 cgtgatgagt gtagaaacag actgctcgcc agctatggca gcaatgctag gttcttcttt
    35281 agcactatca atctcagata tcccatttga cggcccaatc gcaggcgtag aagttggtcg
    35341 tgtaaatggc gagtacgtct tgaatccaac agtagaacaa gcagaacaaa cagatatcga
    35401 attgactgtt gccggaacga aacaagccat caatatggtt gaaagcggcg cgaaagaagt
    35461 ttcagaagaa gacatgcttg gtgcattgct gtttggtttt gacgctatca aagagttagt
    35521 tgctttccaa gaagaaatcg ttcaagcagt agggaaagaa aaaatggaag tgactttact
    35581 gcaagttgat gaagtattga aaaaagaaat ctttgatgct tcttacgcta caatgaaagc
    35641 agcagtaatg actgaagaaa aacttgctcg cgaagataat atcgagcagg tgaagatcga
    35701 tatccgcgaa gcttatgctg agaaatttgc aggtcatgaa gatgaagatc acttgttgaa
    35761 agaagttaaa caaatcacag aagatcttga aaaagatgtc gtacgtgaat tgatcaccat
    35821 cgataagatc cgtcctgacg ggcgtaaatt ggatgaaatc cgtccattgt catcagaggt
    35881 cagcttattg ccacgtgtac atggatcagg tttgttcaca cgaggacaaa cacaagcttt
    35941 atcagcttgt acactcgcac ctctaggaga gcaccaaatc attgatggtt taggggtgga
    36001 agtcagcaaa cgattcatcc accactacaa ttttcctcaa ttttctgttg gttctacagg
    36061 acgtgcaggc tctccagggc gtcgggaaat cggacatggc gcattaggtg aacgtgcgtt
    36121 agcacaagta atcccttcag aagaagaatt tccttatacg atccgtttag tagcagaagt
    36181 attggaatca aatggttctt cttcccaagc aagtatctgt gctggcacat tagcattgat
    36241 ggatgcaggt gtaccaatca aagcgccagt cgccggtatt gcgatgggac ttgtttctga
    36301 tggtgaaaac tatacgatcc taactgatat ccaagggctg gaagatcatc ttggcgatat
    36361 ggactttaaa gttgccggta caaaagatgg tatcactgct ttacagatgg atatcaagat
    36421 tcaaggaatc acagaacaaa tcctaactga agcattaact caagcaaaac aagcacgtat
    36481 ggaaatctta gaagaattga cttcaacgat tgctgctcca cgtgaagaat taagccaata
    36541 tgcaccaaaa atcgaaatga tccagatcga acctgctaaa atcaaagatg ttatcggtaa
    36601 aggcggcgat acgatcaacg gaatcatcga tgaaactggt gtgaaaatcg atatcgatca
    36661 agatggaaaa gtaagtattg cttcagctga tgcagaaatg atcaaaaaag ctatcaagat
    36721 catcgaagat ttgaccaaag aagtcaaagt tggtgaagtt tatctaggga aagttgtccg
    36781 tatcgaaaaa ttcggtgcat tcgtcaactt gatcaaagga aaagatggac ttgtccatat
    36841 ttcccaatta gcaaacgatc gtgtcaataa agtcgaagat gttgttaaac taggtgatga
    36901 gatccttgtg aaagtaactg aaatcgataa acaaggacgc gtaaatctgt caagaaaagc
    36961 aatgttgaac gaagatggtt caacgaaaaa tgaagaaaaa taatttaatt cataggaata
    37021 atgtacttgt gatcgtgaag gtgacagggg gacaataatt attcgaaaaa aggggactgt
    37081 gacaaaagcc gtgtcacagt cctttttttt cgaataaacg gtgttcaaaa gcttgcatct
    37141 gcggtaataa gtccagccaa gttaaaaaca ttaggagctg tttttatttg gctgttctta
    37201 ttacttgatg cagaacagct tttttacaac ctctccaata aacgatgttc aatcagctgt
    37261 ccctcgatat tagctcaaaa aacggcaaaa tatgaggaac tatttttccg tttgtttctc
    37321 taatactcag gtcaaaccgc tgatttcaca acctctgatt cacggtgttc cagaagcagc
    37381 ttctacggaa ataagctgaa cacttttgtt acaacttctt tttttctgga gtttcttggc
    37441 gcatattttt ggagtccttc tgaataaagc gtaaaataaa agtgagaaat atggataaag
    37501 gagggaaagg agatgctgaa ttttttatgg tcgttattta tcggcggtat attaggtttg
    37561 atagctggcg caattttagg aaaggaagtc ccgggaggcg tatctggaaa tatcattatc
    37621 ggttttttag gtagttggct cggcgaattt ttactaggac cactgggacc ggaactcggc
    37681 ggtttttatt tgataccagc attattgggt gcaatttttt gccttgctct ttattcattt
    37741 gtggcaagac gtatcagaga acgtccaaag aaagaataat tttattcaaa taagttgaca
    37801 cttcagtgtg ttacttggat aattagaagc aatttaggaa agcgggtgtc atggataaga
    37861 atatcatcta tcattcaagc ttacctaaag gatatccata taacaagaaa tgagggaaaa
    37921 acgtggcaac aacgcacaat accaaaaaga tatcaatggc tggcctgctt gtagcgatgg
    37981 gagtcgtcta cggagacatc gggacaagtc cgctttacgt tatgaaatcg attgttgaag
    38041 ataatggcgg attgtcagga atcaatcctg attttgttat cggatcagtc tcattgattt
    38101 tttggacatt gactctactg acaacaatca aatatgtcgt gattgcattg aatgcagata
    38161 accatggtga aggtggaatt ttctcactct acacacttgt ccgaaaaggt gggaaatatt
    38221 tgatcattcc tgcaatgatc ggaggagctg ccttactagc agatggggta ttgacccctg
    38281 ctgtgacggt aacgactgcg attgaaggct tgcgaggaat tccgcagttt tttgaccggt
    38341 tcggtaataa ccagaacgtg atcgtcatta tcactttagt tattattttt gttttattca
    38401 tggtccaacg ctttggtaca gatattgtcg gaaaagcatt cggaccaatc atgttcgctt
    38461 ggtttacttt tttaggcgta atgggattaa tgaacttcag tcaagactgg acagttatcc
    38521 gtgcactgaa tccttattat gctatccagc tgctttttag tgcagataac aaattaggct
    38581 tgttcattct tggaaatatt ttcctggcta cgacaggtgc agaggcgctt tattccgatc
    38641 ttggacatgt cggcaaacga aatattcgtc tgagctggcc ttacgtcaaa atttgtttgg
    38701 ttatcaatta ttttgggcag gctgcgtggt tgttgaatgt ttatcaaaac cctgaagcac
    38761 agcaaatcaa gaacctgaat ccattcttcc aaatgatgcc tcaaagttgg atcgtgatcg
    38821 gcgttgcttt tgcaacagtc gctgcagtca ttgcttcgca agcattgatt acaggttcgt
    38881 ttacgctagt ttcagaagca atcaagttga aactgctgcc tcggttaaag atcatgtatc
    38941 ctgggaacag tatcgggcaa atgtatatcc cagcagtcaa tctgatttta tggatcgcct
    39001 gttctctagt ggttgtcaca ttccgaacgt ctcatcatat ggaagctgct tacggtctat
    39061 cgatcactgt gacgatgttg atgacaacag cactgcttta cttttatctt atccaaaatg
    39121 ggcattctcg ttggcttgca tatttagtta cctttttctt cggtgcgata gaagtcgttt
    39181 tctttatctc aagtgttgtc aaattcttcc gaggcggttt tgtagccgtt ctgattggtt
    39241 tgatcatctt agtcgtgatg tttatttggg aacaagggaa cattattcgc gaatcgtcaa
    39301 ccgaggatgt gtctttgaga gattatatcc cgcagcttag agaattacgt gatgatactt
    39361 ctttaccaat ctatcagaca aatgtggtct tcttggttcc tgatatggct gaagataaag
    39421 ttggccgaca gttcatctat tcgattttag ataaacggcc taaaagagca cgagtctatt
    39481 ggtttgttca tgtggaagtg acggatgagc catatacgaa agaatatcaa gtagatatga
    39541 tggacactga ttttattgtc caagtgaatc tgttcttagg tttcagggtc caacaggaaa
    39601 tcaacgtata tgttcgccaa gtcatccatg atttgatgaa acaaggccgt ttgccaaaac
    39661 agccacaaag atactctctg acaccagggc gagaagttgg cgatttccaa tttgtcctga
    39721 ttgatgaagt agtttccaat gtgacaactc taggaaaatg gcaacgtcaa atcatgcagg
    39781 caaaactggc aatcaaaaaa atcgctacct cgccagaaac atggtttggg ctagagtaca
    39841 gcgaagtaaa acatgaaact gttccgctta tcattggaaa tactcggaaa acatggttga
    39901 aagagcggtt gtgaaagtag cgctttgacc tgaactaatg tcgaatgtca gctacttgaa
    39961 caccgtttat cagaggtcat gaaaaagctg tactgcaaca agcagtaaga acgagcagat
    40021 aaaaacagct tctcatgttt ttcatctgtt tgggcttaat gccgtagatg caagcttttg
    40081 aataccgttt ttatcagagg tcatgaaaaa gctgtttagc aacaagtaac gcaatgattt
    40141 tgaagtgata aggagatgtg gctgaaaaat gccgcatctc cttttttatt cctaaatatg
    40201 aatacgcatt attttcaatc tttttgtaga aaaagggtac aatagaaaaa gagaaaggcg
    40261 ggagaatatg gttatcaatt tcattatttt atttttgatg attgcaatta cttcattttt
    40321 tgtagcaagt gaatttgctt tagtgaaaat cagacgatca agattggaac aactagaaaa
    40381 ggaaaatgta aagaacgcca agctagctct tcatgttaca caccatttag ataactattt
    40441 atcagctagt caattaggaa ttacgctaac cggtttgatc atcgggtggg tcggtgaagg
    40501 atctgtcgcg gctttactag aaccagtgat cggtaaacta ccttttagtt cggctattag
    40561 cagtacaatc tctgtggcgc tgggatttat tttagttacg tatatcgatg tggttattgg
    40621 cgaactgctt cctaagagct atagtatcgt caatacggag aaggtcgtct tgttcgtagt
    40681 taaaccactt cattattttt ataaagtaat gtttcctttt atttgggtat tgaatcattc
    40741 agctgcaggg ctagggaagc tattaggtgt gcgtctcgta tctgaaggag aagagacatt
    40801 gtctcaagaa gagctgacat tagtcgcatt gaattcttat gaaaaaggag agttgaccaa
    40861 agaagaatat tattatttgg aaaacgtgtt tgaatttgat gataccttgg caaaagatat
    40921 acaagtagac cgtacgtcca tgcaagtatt cgaagcttca gaaaccgtca aagaagcgat
    40981 aaaagcttcg attgaacaag gacatactcg ctatccggtt atcttagaat caaaagacaa
    41041 tgttttaggt tatgtcacct tgccagattt gatcaagcaa tcttataaag atgaccagct
    41101 gacagtagaa cagttgattg aagagccgat cgtaacaact gaaacgatcc ctataaaaaa
    41161 attattgacg atcatgcgaa aaaagggtaa gcatattgct atcttaaaag atgaatacgg
    41221 agggacaagc ggcttagtga cgattgaaga tattttagaa gaaatcgtcg gggaaatccg
    41281 agatgagaca gatttggacg aagcattgat agcggaacag tcagatggct cttatatcat
    41341 ctccggcaaa ctaacattag atgatttcca gcgttatttt catgtagaga ttccagagtt
    41401 tgaagaaacg aattttacta cacttgcggg ctttgcttct agccgatata aagaaataaa
    41461 agcaggaaca atcattgaga ttgcatcatt ccgtttcacg gtattagaat accagcatgc
    41521 acatatcgat tatttcaaag tagagtccac ggaaagaaaa acagaataaa agaaaaaagg
    41581 ctgtgacatt ttttgtcaca gcctttttgt tatctaaaaa acctgttttc ggtaaacgaa
    41641 gaagatattt tcaataaaag ttttcatttt tagccgcaac gatttctttt aatcaaggct
    41701 atcttgcttc tgcatgttct aatgtgaaat gttcctcttc acccatgtgt ttcaattgtt
    41761 tcatcgaacg catataagag taaagcaaca cggcaacaga accgatccaa gctaaaggag
    41821 aagctgctgc tgctcctggg tatccccaca ttcctgtaag aacgatagct gcaaaagaac
    41881 gcataagcaa ttccatcata ccggcgatcg tagggatctt gctttgtcca agcccttgaa
    41941 gtgtgtagcg taaaatgaac aggactgcta agatccagta aagagaccca ttgatattga
    42001 agtaggtttg tgctaattca aatacacgtg tttctgatgg gctaacaaac aattgaacaa
    42061 agaaatgacc gaagaaaatg acgatagcac ctgctaagag actaaatccg acactcatca
    42121 gtaaagtttg acgtacccct tgcaagattc ggccatattc tttcgcacca tagttttgtg
    42181 cagtgaaagt tgccattgca ataccaaatg acatcatcgg ctgatttgca aattggtcga
    42241 tacgaccagc agcggcttga gcagctacga catctgtccc tagactattt agtgctgctt
    42301 gtaacacgat agcaccaaca gcgatgatcg aagattgaaa cgccattggc aaagcagcat
    42361 ttaggtgtac agcaaactct tctttttcaa atttgaaatc ttttttgcgt aactgtaaca
    42421 aaggcatttt tttcttgata tacactagac acagtacgct ggaagaaact tgtgcgatta
    42481 ctgtagcaat agctgcacct tccacaccca tgccaaaata gataataaag atcaaatcaa
    42541 gtacgacgtt gatgatgacc gcaatgatca gaaagaatag tggtgtgcgg ctgtcaccaa
    42601 gtgcgcgaat gacattagaa agcaaattga aactgactga tgcaaagatc cctaataaaa
    42661 taattgaaat aaatgtttgt gcttgatcaa gtatttcagg aggagtttgc atcaattgaa
    42721 gcatcggacg aataaacagg agacttagga cagttaaaat cacagtgacg acaagactaa
    42781 tgacaacact agcagcaaaa cttttcttca gaccccgata atcttttgca ccgtaacgtt
    42841 gtgcggtaat aatggctaaa ccagctgtta aaccttgggc aaagccaatg atcaaaaatg
    42901 tcaggcttcc agttgcacca accgctgcca gcgcattttt acctagcgtc tgacccacga
    42961 tgatcatatc gatcatattg tagaactgct gaaaaacatt tccgatcagt aaaggaacag
    43021 tgaacatcaa aatcagttta gcggggcttc cttttgttaa atcgcgcatc ttttaaactc
    43081 cttatatctt taaaatttag ttagtagtat atagcgttta tcctgagaat accaattaga
    43141 aatcaatgat aatttatgaa actccataaa aagaagccaa gaattgagtc aaagaatcaa
    43201 caacttggcc tggtctgtaa aataagggac atccacgttt atctatcacc ttaatattgt
    43261 ctaatctcac ttggtaaaag gatcgtttct ctcgtaccgt catcataggc gtatacttga
    43321 gcaggaaatt ggttcgaata ggcaaacggc aaatcaatat ccatttccac attgcttcct
    43381 gcttgagaaa aatgcatcgt cacttttcca cgattttcga tcaaatcaaa ggttaatata
    43441 ttttctaatg gaatgactcc cttaagatct aggtcaataa taaaccatat actgtcaatc
    43501 aattcatctg gcaaacttga tacgacacca actgaagcgt aacggttgcg gctgctatca
    43561 aaactttcaa acatctgttt aacctccttc gaatcaacga atgttttatt tttataatta
    43621 atcctaggat aaactagaaa tacttacttc aacgagggtt cattctaata aagaatcagg
    43681 aaaaatgcaa caataattga atactttttt tcaaagtata aatttttata aaggtacgat
    43741 aaaagtatgc gaggaaaagc ttggtaaatt aggatttttc gtttgtaaag ccatttacaa
    43801 aagtggaagc cccatatgaa aataaacgat tagaaataaa aaaggcgtgt taaaagctgc
    43861 tgacccgccg cttctaacac cacctgattg tttcagtatt attcttctgt tgaaccgatc
    43921 acttctggtt cgccaccttc acctgtgctt tcttcttctt cactttgagc gactacagca
    43981 gcgatttgct cttcactgtc ggtcacgaat ttgtaatcgt cgttttttgg aagatcggct
    44041 actgtaatag aatcacctaa ttccaagttt gtcacgtcaa cttcaattcg ttcaggcaat
    44101 ttgtctggtg tagcagatac gactactgta tacaagtttt gagctaacac tccaccagat
    44161 ttagcaccca ctgattcgcc aacaagaacg acttctgttt cgacttctgt ttcttccgac
    44221 atgtttacag atagaaattc tgcatgttcg aaatgattgg taaaagtgtt cgtttggatc
    44281 ttgtgaacca atgtattgac tttttgtcca tcgatgtcca tcgtgatgac tgtgttcgct
    44341 ccatgttcac gcaacaattt gcttagtgtc aaaccatcga atgagatagg ggtactttct
    44401 actttatacc cataaacaac agctggaact ttcccttcgt gacgaagttt gtttcttaat
    44461 gaacggggac gtacttctct tttacttact tctaatgata ctgacataac caaaattcct
    44521 ccttaaaatg tgactgtctg ctttggtaac ggacagattt tatttaagtg aattctaaag
    44581 gctaatctcg tgcacatcat cgaaggcagg gcgcttaaaa aagcgcaaaa ggagagatgc
    44641 gcgcatctcc ccttagaaag tcaggattca acttttctcc accaggtcat tacgctgtgt
    44701 atgagaaatc caattcactt tactatttaa ccgtaacgtg aactgttaat taagtcaagg
    44761 aataactatg atgatgtatt tgcaagcaag aatattcaag gtataattaa ttagtagtaa
    44821 taagaaagga aacagcatgc gtttagataa attaatagaa gaaaaattag aaacgacacg
    44881 caaggaaatg aagcggctgt ttgctttgaa gcaagtgatg atagatggca cagtcgaatt
    44941 tcgacaaaat cgaaatgtag atagtttact gcatcaaatc gaagtagcag gtgaacactt
    45001 agaaacaaat gagtcctatt atcttctcaa taaacctgaa aaagctgtta cagctgtatc
    45061 agatccagaa aagacgacag taatcgatct gattgcaagt gccgatcgtt tccaaccatt
    45121 atatccagtg ggaagactag atagagatac aacaggacta ttgctgatca cttcgaatgg
    45181 acaattggga tatgaaatgc tacttccaga aaaaaaggtt tcaaagactt atcaagtagt
    45241 tgtgaacgaa agggtgacac cggcagacgt aacagcattt gaaaatggaa tcgtattcgc
    45301 tgatgggtat caatgtaagc cggctgattt aaaaatactc aaagcagaca agcaccaaag
    45361 tacggtttta ttgacgatcc aagaaggaaa attccatcaa gtcaaaaaga tgttcttagc
    45421 ccaaggaaag aaagtgaccg cattgaaacg gctaagcatg ggaccattgg aattagatga
    45481 acagctagga gtaggcgagt atcgatcgtt gacattagca gagatgaaaa agttaagtat
    45541 ttattttaaa taggaggtca aaaagatgaa atataaaact ttattgtttg atgtagatga
    45601 tacattgtta gattttcaat taactgaagc caatgcttta agtgctttgt ttgcagaaca
    45661 aggaatcaca ttgacaccag aaatcgaaac cagctataag gctttgaatc atcatttatg
    45721 gcaggagttt gaaaaaggca gactatcacg agaagaaata ataggcagtc gttttgggtt
    45781 acttttccag caatttggga aaacagtaga tagtgatcaa atggaaaaac gctaccgcca
    45841 ctacttgaac caaggtcatg atcttgttcc aggaagtcta gaaatcctga aaaaggtcca
    45901 tccgcatgct gatctttata ttgtgacgaa cggtgtgtcg cacacgcaac atcggcgatt
    45961 aacagatgca ggaatgcttg attacttcaa ggatatcttt gtctcagaag ctgtcggagc
    46021 gcaaaagccg atgaaagaat tttttgatca tgtcttttcc cacattccta attttgataa
    46081 aaagcaaact gtgatcattg gtgattcttt gacttctgat atcaaaggag gaaatatggc
    46141 agggatcgat acgatttggt tcaatagaaa taaattacca gaaatcgaag aaatccagcc
    46201 tacttatcga atcgattcat tagaggaact ttattcatta ttggaaattg aaaaggatta
    46261 attttcagaa aaatatagca ttttcgtgtt ttttcgctat aatagattag aatgaaaaaa
    46321 cggatacgaa agaggtttta gtcaatgaca aaaagcaagc caattatcat tggtgtgacg
    46381 ggtggatccg gaagcggaaa gacaagtgtc agccgtgcga ttttcaacaa cttcccggac
    46441 cattccatca tgatgcttga acaagattct tattacaagg atcagagcca tttgagtttt
    46501 gaagaacgat tgaacacaaa ttacgatcac ccatttgcct ttgataatga tctgctgatt
    46561 cagcatgtag gcgacttact gaactataaa gccattgaaa aacccgtgta tgactatgta
    46621 gcgcatacaa gaagtcaggc aacgatcatt caggaaccaa aagaagtgat cattctagaa
    46681 ggaatcctga ttttagaaga cgaacgtctg cgtgacttga tggatatcaa agtatacgta
    46741 gatacagatg atgacattcg tatcattcgt cgtatcaaac gggatatgga agaacgggga
    46801 cgcacattgg actccgtgat cgaacaatat ttgacagttg ttaaaccgat gtatcatcaa
    46861 tttatcgaac caacgaagcg ctatgcggat atcattgttc cagaaggcgg agaaaaccac
    46921 gttgctattg atttgattac aacaaaagta gctagtttct taaaccataa atagtgcgca
    46981 gcgaaacagt tgaacggact gcgaccgttt gaaaagcaag gattctgctt tttgaacagt
    47041 caccagccaa ctgttttttt atttataaca agaggttgtg aaaacagcat cttgacctaa
    47101 gtattaaaaa gaagaaacgg aaaatagctg tttatatttt accgtttttt gagctaatac
    47161 cgaaggtcag ctgattgagc accgtgaagt agaggttgta aaaaagctgt ctttgcatca
    47221 agcgataaga gcatccaaat aaaacagctc ctcacgtttt tcgttgggtt gggcttatta
    47281 tcgtagatgc aagcttttga acaccgttta acgagaggtt gtaacagaag tggtcagatg
    47341 caataaataa gaagaaactt acgaaaatta tttctcgaat ttgtgtgaga tttcgactta
    47401 tttttttgaa gaagctcttt tgtcgcaccc cc
//
LOCUS       DAPBCF010000020        44909 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.020, whole genome shotgun sequence.
ACCESSION   DAPBCF010000020 DAPBCF010000000
VERSION     DAPBCF010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 44909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44909
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.020"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            212..604
                     /locus_tag="RD508_001342"
     CDS             212..604
                     /locus_tag="RD508_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7735952.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="RD508_001343"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="RD508_001343"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HDT7735953.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="RD508_001344"
     CDS             3165..4775
                     /locus_tag="RD508_001344"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HDT7735954.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="RD508_001345"
     CDS             5067..5936
                     /locus_tag="RD508_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HDT7735955.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="RD508_001346"
     CDS             6101..7372
                     /locus_tag="RD508_001346"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDT7735956.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="RD508_001347"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="RD508_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDT7735957.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="RD508_001348"
     CDS             8763..9026
                     /locus_tag="RD508_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HDT7735958.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="RD508_001349"
     CDS             9471..9920
                     /locus_tag="RD508_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7735959.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="RD508_001350"
     CDS             9977..11395
                     /locus_tag="RD508_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7735960.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSISTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="RD508_001351"
     CDS             11395..12255
                     /locus_tag="RD508_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDT7735961.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="RD508_001352"
     CDS             12429..13202
                     /locus_tag="RD508_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7735962.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="RD508_001353"
     CDS             13349..13714
                     /locus_tag="RD508_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HDT7735963.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="RD508_001354"
     CDS             complement(13862..15070)
                     /locus_tag="RD508_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7735964.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="RD508_001355"
     CDS             complement(15089..15367)
                     /locus_tag="RD508_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735965.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="RD508_001356"
     CDS             15521..16216
                     /locus_tag="RD508_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDT7735966.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="RD508_001357"
     CDS             complement(16658..17455)
                     /locus_tag="RD508_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HDT7735967.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="RD508_001358"
     CDS             complement(17452..18636)
                     /locus_tag="RD508_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HDT7735968.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="RD508_001359"
     CDS             complement(18661..19908)
                     /locus_tag="RD508_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDT7735969.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="RD508_001360"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="RD508_001360"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDT7735970.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="RD508_001361"
     CDS             21888..22202
                     /locus_tag="RD508_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDT7735971.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="RD508_001362"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="RD508_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDT7735972.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="RD508_001363"
     CDS             22887..23531
                     /locus_tag="RD508_001363"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HDT7735973.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="RD508_001364"
     CDS             23546..23875
                     /locus_tag="RD508_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HDT7735974.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="RD508_001365"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="RD508_001365"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDT7735975.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="RD508_001366"
     CDS             24863..25687
                     /locus_tag="RD508_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HDT7735976.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="RD508_001367"
     CDS             25680..26027
                     /locus_tag="RD508_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HDT7735977.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="RD508_001368"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="RD508_001368"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDT7735978.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="RD508_001369"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="RD508_001369"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDT7735979.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="RD508_001370"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="RD508_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HDT7735980.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="RD508_001371"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="RD508_001371"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HDT7735981.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="RD508_001372"
     CDS             31657..32451
                     /locus_tag="RD508_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7735982.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNIFSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="RD508_001373"
     CDS             32441..34483
                     /locus_tag="RD508_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7735983.1"
                     /translation="MLYKLAVKSSFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="RD508_001374"
     CDS             34764..34913
                     /locus_tag="RD508_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HDT7735984.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="RD508_001375"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="RD508_001375"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HDT7735985.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="RD508_001376"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="RD508_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HDT7735986.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="RD508_001377"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="RD508_001377"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HDT7735987.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="RD508_001378"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="RD508_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HDT7735988.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="RD508_001379"
     CDS             39330..40412
                     /locus_tag="RD508_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDT7735989.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="RD508_001380"
     CDS             40412..41215
                     /locus_tag="RD508_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDT7735990.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="RD508_001381"
     CDS             41285..42025
                     /locus_tag="RD508_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDT7735991.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="RD508_001382"
     CDS             42036..43040
                     /locus_tag="RD508_001382"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDT7735992.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44848)
                     /locus_tag="RD508_001383"
     CDS             complement(43085..44848)
                     /locus_tag="RD508_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7735993.1"
                     /translation="MLFLTGIAYFFYFIFSPADSNQMKEIKDSWVFYTKDDPDFKFDS
                     KYTRTIPTVDKDETFIMETTLEKPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEES
                     NPGLSLAVIDLPANYIGKKLTLTVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQV
                     LTMIIAVFIAIGTFFYTIYLMYKQKRLEYSLILLSCFALALGFEAVSEDILSGILFEP
                     FVHSFLSHLFIILTSAFIICYYWSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAEL
                     PELMPIANIASVISTLVTSLACIGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGI
                     YQTTINWSTILYIIILIVIISYNLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQH
                     IQEVNTLRLEFVQEMENLQDLMHTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLI
                     LARYQKLAAKRNIQITFQADLPEELPINDDDLAQLLIHALEHSFRETHAIENPLYRKI
                     YLSIHEQEEHFVICCEHSAHYDTNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQ
                     EKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14438 a         7833 c         9344 g        13294 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgattt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttttccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagttct tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatat
//
LOCUS       DAPBCF010000021        37732 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.021, whole genome shotgun sequence.
ACCESSION   DAPBCF010000021 DAPBCF010000000
VERSION     DAPBCF010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.021"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(159..1469)
                     /locus_tag="RD508_001384"
     CDS             complement(159..1469)
                     /locus_tag="RD508_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HDT7735994.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1481..2899)
                     /locus_tag="RD508_001385"
     CDS             complement(1481..2899)
                     /locus_tag="RD508_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7735995.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3139..4707)
                     /locus_tag="RD508_001386"
     CDS             complement(3139..4707)
                     /locus_tag="RD508_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDT7735996.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4711..5121)
                     /locus_tag="RD508_001387"
     CDS             complement(4711..5121)
                     /locus_tag="RD508_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HDT7735997.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5118..6041)
                     /locus_tag="RD508_001388"
     CDS             complement(5118..6041)
                     /locus_tag="RD508_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HDT7735998.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6038..6916)
                     /locus_tag="RD508_001389"
     CDS             complement(6038..6916)
                     /locus_tag="RD508_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HDT7735999.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6903..8240)
                     /locus_tag="RD508_001390"
     CDS             complement(6903..8240)
                     /locus_tag="RD508_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HDT7736000.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8243..9346)
                     /locus_tag="RD508_001391"
     CDS             complement(8243..9346)
                     /locus_tag="RD508_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDT7736001.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9420..10928)
                     /locus_tag="RD508_001392"
     CDS             complement(9420..10928)
                     /locus_tag="RD508_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7736002.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10894..11586)
                     /locus_tag="RD508_001393"
     CDS             complement(10894..11586)
                     /locus_tag="RD508_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7736003.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11608..12582)
                     /locus_tag="RD508_001394"
     CDS             complement(11608..12582)
                     /locus_tag="RD508_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7736004.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12882..13754
                     /locus_tag="RD508_001395"
     CDS             12882..13754
                     /locus_tag="RD508_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7736005.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14212..16410)
                     /locus_tag="RD508_001396"
     CDS             complement(14212..16410)
                     /locus_tag="RD508_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7736006.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16642..17634
                     /locus_tag="RD508_001397"
     CDS             16642..17634
                     /locus_tag="RD508_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7736007.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17694..19115
                     /locus_tag="RD508_001398"
     CDS             17694..19115
                     /locus_tag="RD508_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HDT7736008.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19108..20607
                     /locus_tag="RD508_001399"
     CDS             19108..20607
                     /locus_tag="RD508_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HDT7736009.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20646..22040
                     /gene="uxaC"
                     /locus_tag="RD508_001400"
     CDS             20646..22040
                     /gene="uxaC"
                     /locus_tag="RD508_001400"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HDT7736010.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22199..22882
                     /locus_tag="RD508_001401"
     CDS             22199..22882
                     /locus_tag="RD508_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HDT7736011.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRPP
                     LANYLQKGV"
     gene            22884..23720
                     /locus_tag="RD508_001402"
     CDS             22884..23720
                     /locus_tag="RD508_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDT7736012.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23731..25485
                     /locus_tag="RD508_001403"
     CDS             23731..25485
                     /locus_tag="RD508_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7736013.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25761..26102)
                     /locus_tag="RD508_001404"
     CDS             complement(25761..26102)
                     /locus_tag="RD508_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDT7736014.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26170..28341)
                     /locus_tag="RD508_001405"
     CDS             complement(26170..28341)
                     /locus_tag="RD508_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HDT7736015.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28510..29409
                     /locus_tag="RD508_001406"
     CDS             28510..29409
                     /locus_tag="RD508_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDT7736016.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29480..30337)
                     /locus_tag="RD508_001407"
     CDS             complement(29480..30337)
                     /locus_tag="RD508_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7736017.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30322..33024)
                     /locus_tag="RD508_001408"
     CDS             complement(30322..33024)
                     /locus_tag="RD508_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDT7736018.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33037..34326)
                     /locus_tag="RD508_001409"
     CDS             complement(33037..34326)
                     /locus_tag="RD508_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HDT7736019.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34476..35522
                     /locus_tag="RD508_001410"
     CDS             34476..35522
                     /locus_tag="RD508_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7736020.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     SYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35524..37677
                     /locus_tag="RD508_001411"
     CDS             35524..37677
                     /locus_tag="RD508_001411"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HDT7736021.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
BASE COUNT        11154 a         7776 c         6706 g        12096 t
ORIGIN      
        1 acgacttagt tatcttatca cgtctaaaaa catgtgtcaa ctcttttttg gaattttcat
       61 aaaatgtttc aatgaagcgc gacaacgttg tttaatatat cattaaaaaa aataaaggtc
      121 aagctaaaat attatttaag cttgacctta ttataatttc aacgattgtc aaaagtattg
      181 tttgcagctg tgttgccagt ttctatagat aaatcacagc ttttgaaaca taagttttgt
      241 actgcttcga ttcgcccgaa ttcttttgca gttatttggc aatgagaaaa gcagacatct
      301 tctataggct tttcaggaaa tgctactaaa tcaaaagctc gggaaggaag tgagtaacct
      361 ggagaaaggc atgcctgtac gtttttgatg tgtatgtctt tgactttcgt catttgcttt
      421 gattcaggta tttcttcagc cactgcttgc caactttctg gcatttgagc aaggtcattg
      481 ctattttttc tattgtattc attatgccag tccattatcc aagaaaaagg aaattgtaca
      541 tcaatcatat tcagattttc taccctgata ttttcgatca ctccccctct ttcttttgaa
      601 gatttcattc gaataccaca gtctgactga aaaaaatcga tatcgtgaat atatacgtca
      661 ctaactccag cactaacttc gctaccaata gttacaccgt atcctgaacg gattttacat
      721 ctagcaacct cgattcttga tgattttcga ttgactcttg caccattgcc atctctgcca
      781 gacttaatag caatacaatc atcaccacag gccaaatcac attcatagac acgcacattt
      841 gttgaagaat caatatcaat cccatctgta cttggtccat cattgttgcg gatgattact
      901 ttttctacta atacatcgtt agaataagtg atttgcaagt tccaaaaacc tgatttctga
      961 aaaatcaaat cacgaacaac aacatgttct gcatgataca gtaaacaagc gcgtggacgt
     1021 ttaatagcat aatccgcaat ccaacgaagt cccttttgat cgtattcagc tcttgtcccg
     1081 cttttttgat cttttcccca atacagctcc caccaatggt ctccttgacc gtcgattatt
     1141 ccttttcctt ctataagaat atctttcgcc gagagaacat tcaaaatcgc tgctggccat
     1201 ttcatttcta cgccggctac tcgtgtatcg atttctggaa atgcttcgat atctgttctc
     1261 cccttgagga ctgcaccttc ttcaaagata agatgactct tatcttttaa aaaaagggct
     1321 ccgactaaat aaatgccttt tggaataaat acaggtaagt gttctttcgc accttgatcg
     1381 attgcttttt gcagtattat tgtatcatct tgttgagtgt cgtttgtttt aaagttcaaa
     1441 gcattgataa tccctttttt tgtccgcaat acgtttctcc ctatctttca ttgatttttt
     1501 tcaattcttc accaataaat acagtttttg aacgattcag tgggtaacct actagcaaaa
     1561 tgattgcgga tacaaataag cagaatgctg gtaacaagtt tgccatcgta taaatccttt
     1621 cttgtactaa aactgattgg atggctccac ctgttgtaga cgattggtaa ccaatgagtg
     1681 ccagcataaa tccgcctacc gctcctgcac atgcttgtcc tacttttctc gcaaaagaat
     1741 ttactccata tactgttcca tcttctctta agcctgtctt atattgatga taatcaatca
     1801 cgtcagtaat gaatgcccag accatcaaat tgaataaacc agatcctaaa gtagcgataa
     1861 ataaaagaat cagatatacc catgcatttg ttatatgaag gaaatacatc agcaagtaca
     1921 tacatgaaga agcaagtaac gcaaatacgc ttgcttcctt tttaccaaat aattttgtca
     1981 gctttgtagc aaatggtgct aaaactacta ctgttccgta agtaaataaa agagcaacag
     2041 acattgcttg tttattatgg aagtaatcat tgaataaata agtcatattc gtcccagcta
     2101 aaatctgatt gatcacaatg aaaatgtcaa caatgactaa aataatcagt gctcgattag
     2161 ctaacaaacc ttttaccaac tgagaagcag atactttttc gtttttgaca actcttactc
     2221 tttcagtagt caatttacaa gttaacatat atgcgacaaa tgctattgca gcacatccga
     2281 ttgaaatcca aaagaaatga ttccctgaaa cgacttgttg tccactcttg ttatgggtat
     2341 acattaaaat cggaatgaag aatcctgtag ttgatccgcc aatcgcagaa ccaatgcttc
     2401 ggaacgtgga caacgaggtg cggtcattag gatttgagct aattgctgct gccattgctc
     2461 catacgggat attgattgtt gagagaaaaa tcccataaac aatgtatgaa acaaaaatat
     2521 aagcaatctt caccgtcatt ggaagatgtt ggacgaatgg caaaaacaaa atgacagtca
     2581 ctaagcaaaa tggatacttc atttttctga tccaaggaat aaatcggcca gtttctgtta
     2641 actctgagac atcacataat cttccaacca tcacatcagc aaacgcatcc aaaattctcg
     2701 aaatcaagaa taacgtacct acgattgccc ctgaaacgcc aagaacattc gtataataaa
     2761 tcatcaagaa actattgact aaacctaaaa taaaacagtt acctagatca ccgaacatgt
     2821 agcctatctt atcggaaatc ccaaattcct ttttttcttt ttttattgta tttgctgtaa
     2881 cagcattttg tgaaagcatt tgaattcctc ctacctcttc tagtaaacgt tttcaaaatt
     2941 ataactcttt ttttcttgtt tttatattca caatgttggc tttttattgc attatcttga
     3001 cagataaaaa acaaaaaata atctaaaaac attgatgcat aagattgata acttttttta
     3061 cataacaata tatacaaaca aaaaaattca ctaactagtg aaaataagtt agtgaacctc
     3121 atttattaaa gaattaaatt acagatgatc ttttccatca tacttgaaaa actcaaaatc
     3181 agcataactt cctctttttt tatttagatc atgcactgct atcccgataa aatttccagt
     3241 aaaccctcct gagagtatac acatgttttt ttgcggacct actttcttcc attcttcagt
     3301 tgatacgtct ttcaaatgaa actgtgctgt ctctttcttt acagtgactt tcaaaaaagt
     3361 cttcttttct gtgagtggaa tcgtccaatc ttctatttgt gctactccgt tttctgattc
     3421 tatcatacgt aggcattttc ccttgtcctc attccaagta acataacaat aaatataatt
     3481 ggattcattt aagtacagta ccagtccagc catctgatta aaattattag gcatgtattc
     3541 aaatgctgtc tccgcatcaa aagtaaaatc cgtttgccga atagctaaca aatgatgttc
     3601 gaaggtagat tgaagagatt caccggaaat cagacgtaaa aaacctggtc tacattttgt
     3661 atcacaccaa tcagcatttg gcaaaatgcg tctggcattc cagttcttct ttagctctcc
     3721 ttcaaatgta tccataaact gatgatcttt ttcttgttgt acctcttcat ttgtctcaat
     3781 cattatttct tccatcggag ttgtctggct atctttaagt cttaaccaat cgtcggacgt
     3841 ccaatacact tcttgaatag cggtttctct tcccaaaata gccgcaccgt ttaatggtct
     3901 ggtacaaaga tatgtcatgt accatcttcc tgacggggtt tgtactaagc tcccatgtcc
     3961 tgtacattgc aatgtagaag caggtttgtc actagctgtc agcataggaa aaccaggatc
     4021 aagctcgtaa ggaccagtaa tattctttgc tcggcaaact gtaactgaat gtcctcttcc
     4081 tgtaccgcct tctgccgtca tcaaataata atacccgtta cgaaaataca aatgtggtgc
     4141 ctccgttttc gctaattctg tacctgcaaa tattttatag atgggaccat caagcttctt
     4201 cttctctgca tcatattctt gtaatacgat accgctggat ttattcggtg tgtccagacg
     4261 ataatcccat agttcattga caagccattt ttttcccgtt tcaagatcat ggaacaaaga
     4321 aggatcaaag ccgttactat ttaaataaat tggttcggac caaggacctg tgatctcaga
     4381 tgcagtgatc aaataattgt ggacatcttt aaacggacgg cctgcacttt tgacatctgt
     4441 gtaaacaaga taaaacaatc catcagcata actgatctgt ggcgcccata tacttccatt
     4501 tgtaggattt ccttgcaaag atacttgagt ggtcaaaata tccgttgtat gtgaccagtt
     4561 gactaaattt ttcgactcat atactcggat tcctggaagc cattcaaaag aggagacaat
     4621 aatgtaatac cgctctttca ctcttaatat attaggatct ggattgaatc ctcttaaaat
     4681 aggatttttc actttgatag tctgcatgat tcaggctcct tttctcattc ttactcgata
     4741 taaactgaat gccccagctg cgaaataaaa aaatgcaaaa ggaaacgcaa taaactgagt
     4801 gccaatcaac aatatgaatc ctgttataaa atacaaacca gtggcagttg ttaagtattt
     4861 tcctttagca gtcaaaaaca atgctactgc taaaaaagca agtgaaataa acaacacaac
     4921 ggcaaacaga ccagtcatgt cctgtaataa tccaaatgta ttttctaaag acaaagttga
     4981 atgatctaca gcaagcgact gataactttt tttaaactct gacgcagaca tattacttaa
     5041 agtaactgct aacccgccaa agaaaatcaa agatagactg ccaccgacca ttcctagcaa
     5101 tagttcccat tttcttttca tttctgaacc ccctgctttt ctaaatgtat ccattcaggt
     5161 cttttgatcg atgtttcata attgttatta cgttcagaga atttgacagt ctgttcattt
     5221 ttcttgtcat cccaattatc ccaaccagtt gggtgaacat gcccacctat cttacacgct
     5281 tcaaataaga catttgcata cggacgccac ggtcttccta aatagacgtt tctagtatca
     5341 ggttctgcag tcaaggtaca gctttcaaaa cgataccctg ttttttgatt tttcggcgta
     5401 gatgctgctg tgatgtatcc aggattttta ctggctaagc tatggatatg acactgatga
     5461 aaaacggcat ctgccccacc aaatatgaaa tccaccgttc cttcaatcca gcaatattca
     5521 taggtctgac gacaatactc aggattggca gaagccggtg tacaaaaagg agtaccatct
     5581 ttttgcaaat caggcaacgg acccgtgcat aaggtatcct gataaccaga tagtcgacag
     5641 ttttttaaag atacgcgatc tcctgaattg aataaagcaa cagcctgtcc taccttttct
     5701 cctggacctg ctgtattttc gatgtgaaga ttttctaata cgacattcga tccttctaag
     5761 aaaaaagtag cacttcggaa agtccctaac tggctaccgt caagatactc ctgttttgca
     5821 aaacgattac cggagataac tactgttcct gctcccacaa gtttaaaatt ggataatctg
     5881 ctttctatat attcatcata tcttccttct tttactatca agacctttgg atggctatcc
     5941 ggcaggcctg ccaaataatc gattccttct tggatagttt caaaatccgt cggggtatct
     6001 atagcattct ttccaattat cagtttgtct ttcatcctca taaatgctcc cttatgaatt
     6061 gtttccaaat atttctcatt tcttgtgttt ccatatgacc gcctgttaaa gaaaaagaag
     6121 aaaagttttc tggactaccc attgattgat actttttgtc cagccctttt ctcagcttca
     6181 gtacgccttc gtccaagcac atcgtatcgt tttttccaac taagctaaga cgagggcgcg
     6241 gagcgatttt ttcttggatt gctaacgttg tataagctgt caatagattt ggcacatagt
     6301 aataaaaccc atgatgatct aggcggcgat gtagcaaaag tatttcgatg tccacctgtg
     6361 ccgctagatc aatacaaact ttgacacgag aatccaatgc tgtcacccac cagcttaata
     6421 agcctcccat agaaagacca atcgttgcga gccgttgagt atctgtgtct tcccttgtct
     6481 ccaaataatc gatcaagctg atcacatcat aaatacgcat tccccataac gtttttcctg
     6541 ttaataaaaa ttgtttgaac aactcgcttt cagaaatacc tccgcgttct tcaaatcccc
     6601 aagcatcaat cgaccaaaca gcatatccca ttcctgtcag tacttctgca aaagatggag
     6661 aagctaagta aggagcacca tggatcaatt cacttttccc gactgaaaaa tctccgccgt
     6721 gagaatgcag gtaaaggacc ggcggaaacg gtccttcttt ttctggataa gcatagaggg
     6781 ctggtactgt ttccaattca tttaagtaca attgatagta ttcaagcata aaaccgtttt
     6841 gtttttctcg gtataatcgt tttccactag gggtatgtct gctagatgga gcacctaaaa
     6901 aatcattcaa ctgcataagc aaagttttta cgaacaacca gttcatccat attttctgat
     6961 tgatttgatt ggaatttctc aatactgatt tctttagtat tttctaatag aaatgctggt
     7021 ccctcgtgat tttcaatcga catctggtta aaggaaacct tacccgcaaa gccaatataa
     7081 aatccttgtc tgctcatttc ctctattcct gtcatcatag caggaacacc gggaactgca
     7141 tcttgggcca tcgagacatc gatattgtca aatgtgattt cttgtatgaa ttgttccgct
     7201 aatccataaa taaaacctgc agaagcatgg acattccttg ccgtgatatt cgaaaaatgg
     7261 atccttctga atgctggtgt ccgttcatct atcggataag cctttttttc ccatacatac
     7321 ggttctttcc ctcgcggacc acagaaataa taaagattca gtataaatgg acacatcaca
     7381 ttatccatga ctatattgga tactcgaata tcttcaacga tcccgcctcg acctcgtcta
     7441 gatttcaatc gtattcctcg atcagtttct tggaagatac aatttgaaat ggtaatatta
     7501 cgaatactac cactcatttc acttcctaat acgacaccgc catgtccatg gaccatcgtg
     7561 caatttgtga tcgtgatatt ttcgcaagcg atcctttcgt acgtatcttc agtccctgcc
     7621 ttgattgcaa tacagtcatc tcccacgtca atatggcaat tactaatacg cacatttttg
     7681 catgattctg gatcaattcc gtctgtattt ggtgaatccg ctgggttcaa gatcgtcaag
     7741 ttatcaaacg ttgcattact gcaaagaatc gggttgatcg tccaacttgg tgactggatc
     7801 aatttaatat ctttcacagt aattcgatga cagttatgga aactcatcaa tttaggacga
     7861 ggataagcga gattatctgg ttcatttcta aaagtatgcc accatttttt tccatttcca
     7921 tctaatgtac cgaaaccagt gacagagatg ttctctacat tttgagcata gatacaggaa
     7981 gcataaactt ttcgatggac tccttcccaa cgtgaatgaa caacaggata atcttttgga
     8041 tcgtcagaga atttcagaac cgctcctgcg cttaaatgaa gttcgacatt gctttttaaa
     8101 aataaagctc ctgttagaaa ttcacctgct ggaacaacta cggtcccgcc tccgtcactt
     8161 gctgcagcat caatggcttg ttgtattgct tcagtattca attcatcaat tgatgcgcca
     8221 aatgtcaaaa tatcatacat atttataatg cctccacttc aatcaatgct tgcaagaatg
     8281 caccaacgcc tttttgatca ttacaaataa ttggttcact gatgtagtaa gcatatgaac
     8341 catctcgctg atctgctccg cctaaccctg ctacttgaca gtttttattc aagttcagcc
     8401 agccttcttt tgtttccaga acaaattcat caagtaatcc ttgatgtgat ttcttcactt
     8461 gtggaagcca ttcttctttg ttcagcagtc ccaaacgtat tcctttagcc attgcgtaaa
     8521 caaacatact actgccggaa gcttccagat aatttccttt ccgttttgtt tctgttgtta
     8581 cttgatacca tgtcccgctg ttttcttctt gatatggaag taatgcagcc agtgtctttt
     8641 ctagaatttc tttcagcaaa gaacaatctg tttcttcatg aagtaattca taggtatctg
     8701 ctgcagccat caaataccag ccaatcgatc ggctccaaaa atgatgggat agacctgttt
     8761 ttggatcagc ccatggttgg accttctttt catcccatgc atgaatcagc aaatttgttt
     8821 ttggatcgaa tagatgttta taactgattt caaactgtct caaaacatct tggtaatctt
     8881 tttcttcact aaaattctgg ataaattcag cataaaaagg agaacccata tataagccat
     8941 ccaaccaaat ttgataagga taaatttctt tatgccaaaa agctccttcg gatgtgcgtg
     9001 gatggtttgc caactgctgg gaaaggagtt ctgctgcttt tttatatttt tcttcgcctg
     9061 tttctttgta caataaaaag aaaagctttc ctgtatttac atggtcgata ttgtattctt
     9121 caacgctgta gccacggatc gttccatctt cttgcacgaa atagtcgata ttgtctttta
     9181 tgaaatcaaa ataaattttt tcttgggttc gttcccaaag taattggaac cctttaagta
     9241 cgacgccata gtcataagac cattttcctt tataccactt ttcttcatat aagcgaggtg
     9301 ttctttccat gatacttttt gctaatttct ttgaccagtt ttccattatt tgctctcctt
     9361 taaaaattaa aataggattt gggacaaata ccaagaagta tttgtcccaa tcgtctatat
     9421 tactgtgccg ctgctttgta tgcttcctcg tactcttgtg tgattcgatc gcctccttgt
     9481 gctttccagt cttctacagc ttttttgaat ccatcttcgt caagctgtcc catgatgtat
     9541 tgcaccgtag catcaatgac gattttttca atttctgatc ctacttcatt gttcgtcggt
     9601 gaatccaatg gcacagaagg atccattaca gcaaattctt cattttcttt gatcaattga
     9661 ttagagaatt ctttttcagg gtctgtatct ttgaaagaga acgtcacttc actaggacga
     9721 gagcttgata acggttgcac ctcttgttgc caaagatcca tatcgataaa ttcgatagaa
     9781 ccatcatcat tcaattcata atgcgttcct tcgataccgc cagtcatcaa tttatacaca
     9841 tcttcttcta aaagatcatc aacaaattga agtaatttct tcaattgtgc ttcgtctttt
     9901 acttgagatt tgggaaatgc tagcaagccg ccaataccat ttccttctga ccaaacatga
     9961 taaccgccgc cttcaccatc tgagatcttg tttacaggca ctaattccat atcatcttga
    10021 ataccttgac ccatcgtctt cagattcttg atatccacca ttccagtgta gattccagtt
    10081 cttccttgtg caaattgttc ttgctgatca gtcttttggg taactgcaaa gtcttgtgcc
    10141 aaatagccat tctcaaatag atctcttgaa aaattcaaag ctttcatata ctcttctgta
    10201 tcaaattctg gagtgaattt gccattatcg tctacagccc agccatttgg tgctccaaaa
    10261 taagaagtga aaagtttaaa gctggtataa cgaatatcac taggcgcacg atcgccaaaa
    10321 ccaactgtgt cgtccacacc atttccatca ggatcgtttt ctgtaaattg tttagctact
    10381 tcataaagct catccatggt agttggaaca tctagtccta gattatccaa ccagtctttt
    10441 cgaatgacta agccagcacg agcgtagtct ttttgtatcg gtacgccgta caaggcaccg
    10501 tcgatactcg cagcttcgat tctatcttca gaaatttgac ttaaattttt atagtctttt
    10561 aaatattctg atacatccca gaatacgcct gattttaacg cattgcggac agaagagttt
    10621 ttcaacatcg caatttgaag tgtaacgata tctcctagtt catcagaagc caatgcagtt
    10681 gttaatcttt cttcttttga agcatcagga atccagttga atgtcagttc cgtatcggtt
    10741 ttttcttcga tcaagttcac aatcgtgtct gtaggcggtg aagcatgatg caaaatattt
    10801 aaccaagtga ttttagcttt tccatcttct gtctctgaag aactgttact tgaactgctg
    10861 ccgcatgcgg caagtgctag aattcctgca aaactaagac ctaattttac gagcgttgct
    10921 tttttcataa attttctcct tcactgtttt aataatattt ttgttttctt ctgttttttc
    10981 tgtatatgag ttcttccatt ccaaatggca aaatatagaa tttgctgtcc acgtgactgc
    11041 ggaaaagaag agactgccac cgataaaggt taaaacacct ggcattgttt ggatgatcat
    11101 cagataaatc cctaccatac ttaatatcaa cactaatgag taatgaagat gtgagaatcc
    11161 gaataaaaat gccattttca ttttgaaaaa atatcctttc caatcataat gagccatgat
    11221 tgggaaaata tagagtgctg agagcacata tatgaacgca gcaatataca aagcgatcct
    11281 aagataccaa ttgtgtatga aagaaagatc cacaagtaaa acaatcccga tggcgccata
    11341 tatccagctc atcagcaagg tttcacgata gttttcttta aaatatgtga agtacgtttt
    11401 cgtcaaagga aacgtttctt ttgagcgcag ccattttcta atcactgcaa ccatcgcata
    11461 cgatgcagga ccgaaagtaa aaactcccaa acctgcgatg actaaaccgc cccacagaaa
    11521 attcaaataa accaactgta aaatacgatt tagccttccg tttattttat ctaatgactg
    11581 cagcatatct ttccctctct ttctatctta gtaaacgccg tcttctccta gctttttggc
    11641 aatcttatta gctaaaatta ccataaacaa tcctacgacc cctttaaaca atcccattgc
    11701 tgtactgaaa cttaactgtc cattcttcaa tccagctgta taaatatagg tgtcgaaaat
    11761 ttctgcaacg cttcgattca atgaattcaa taacaagtac atatgctcga accctaagtc
    11821 taatgtctga ccgattttta gaatcagcaa ggtaatgatt actggacgaa ttgccggcaa
    11881 tgtaacatgc catgttttgc gtaagcgtcc tgctccatcc atttctgcag cttcatacaa
    11941 ctgtgtatcg actgcagtta tcgctgaaag gtagatgatc gtagaccagc ccaactcttt
    12001 ccagatcact tgtccgatat atactgtgcg tgtccattca ggggatgtta gaaaactgat
    12061 tttttcaaat cccattgttg caaggaattc attcaatacc cctccgtcaa cattcaaaaa
    12121 tacataagta atcgaaacaa tgattaccca agacatgaag tgagggatgt aaatgatcgt
    12181 ttgaatcccg tttttcaatc gtttgttcgt tacttcattt aatagtaaag acaaaatgat
    12241 tggcatcgga aaaaacacga agatatttaa tccgaacaag atcaacgtat ttcttaataa
    12301 tgtaaagaat gtcggttctg taaacaaacg aatgaaatgt ttgaaaccga cccaaggact
    12361 tcccattatt cctaaaaatg gttgataatc ttgaaaagca ataacgagtc cccccatagg
    12421 aagataccta aaaatcaaga aataaaggac tcccggcaga atcatcacat ataaaaattt
    12481 attcgttttg attcctgcaa ttattttttt tcgtcttctg agcttttctt cttttttcga
    12541 tagcgtcagt tgaaatggtt cttgtttctt tacactttcc ataagcccct ccttagtttt
    12601 gtgaatgttt gctgcttatg acttcatgat agataactat ctgaattacg tatataatca
    12661 tttttaccgt aagtaaaaac gcttacatag caatgatttt tgtgctatac aaaacgataa
    12721 agtgtatttt ttcacaaata aactacgcat agcaaacctt ctattttttt ctatctgaca
    12781 cttagcatag gaaatgatta tatacgtaat ctttcaccga tgataaattg aacatataga
    12841 aacagaaaca tttaatttat tttgaggagg agcctatcta tatgaaaaag aaagtctcta
    12901 taggagaaag aagttttaca cttttcaaca atacgtttct aattttgcta gctttgatct
    12961 gtatcgttcc ttttttaaat atcatcgcta catcttttgc ttctacacaa gaagtcgtcg
    13021 cgaaaaagtt tatccttttt cctactacct tttctttaga cgcgtatcgc tacattcttt
    13081 ctacgccgac catttttaga gcacttgctg tttcgattgg tgttacaggt gtcggaacga
    13141 tcgtcagtat gtgtgcaact tcactgatgg cctacggtct ttccagaaag tatttgtttg
    13201 gtcgaggttt cgtcaacttt cttgttgtat tttctatgtt gttcagcggg gggatgattc
    13261 caacgttctt agttgttcgt tctctagggc tggtcaattc ttactgggcc atgatcctgc
    13321 ctgtggctgt taatgcaatg aatatgatca ttatgagaaa ctttttccaa gccttgccgg
    13381 atagtttgga agaatcagca aaaatggatg gttgcacaga ttttggtgta tttttcaaaa
    13441 ttatgctgcc attagcgtta ccgtctattg ctactatctc gcttttttat gctgttactt
    13501 actggaacac ttatatgact gctattttgt atatcaacga ttcatctaaa tggccgatac
    13561 agattctttt acgccaaatc gtcattgtat caagtgggat gcaagcagaa agtagtgccg
    13621 ttgatgtgat tccaccagca caaacagtta aaatggctgt tatcgttatt gcaacagtgc
    13681 ctatgctgat tgtttatcct tttgttcaga aatattttgt caaaggagca ctcgtaggtt
    13741 ctgtcaaagg gtgattatgt actgaacgca aaatggtagt tgtgtcagaa gtggtcagct
    13801 tcaagaaata agaaggcatt tacgaaaatt gcttcttaaa tttttgtgaa atttcggctt
    13861 atttttcgaa gaatctactc ctggaacacc gtgtatcaga ggttgtgaaa gagacgttca
    13921 gccttgagcg atgataaaaa ctctcacaaa cattgcgacg agtaacccac aggagcaata
    13981 agaagcgatt ttgaaaaata gcttcccata tttcacaaaa ttatgcctta ttgtcgatag
    14041 cctgtctctt gaacgccatt tattcgtaaa aaagaactgt gacaagactt ttgtcacagt
    14101 tctttttgcg tgcttagcct tgaaatttaa ctatccataa atacaaatac tagggttatt
    14161 ctaacttctt ttattgcttg aatcagtcca caagaaaaac agcctcttga ttcacaaata
    14221 tttttttcga tattctcccg gcgtaatcga ttccttcttt ttaaagaaac gaataaaatt
    14281 ttgcggattt cgatattgca atctttctgc aatctctttt acggagaggt tagtctcttt
    14341 caaccatttt tttgctacct ctaaacgatg attttgaaca aaatcaccaa atttttctcc
    14401 tgtttccttt ttaaatacat tacttaaata gttagggtta taatgcaacc tatcagcgat
    14461 cacatctaaa gacagatcac gatcatattc tgtgtagacg atatgcataa tattctccga
    14521 caaattttta aattcatgat cagtgattgc ttgagagcat tctgtgattg gcagaactaa
    14581 ttgttctaaa acaagttttt ctagttcttt gggatgataa ttgttcagtg cttttacata
    14641 aatttgtttc atgttatcaa agttttttga atctactccc aataactgtc ctaattgaac
    14701 gagttcattg atcaagcgga ccgaaactac ttcccgactc aaaggatttt tattttgtgc
    14761 aaacaatgca tcaatcaatt catgtactaa attcttcact tcctgatttc cagaacgaat
    14821 ggcttcaaac aatcgatttt gttcttctat cggatatcta ataagtgttt tttcatgagc
    14881 agcaggaacg atttcctgat aaaaaataat tgaacttgga ccagtattta cacgataata
    14941 cagggcttct tttgcccgat caaccgattg cttgctttca ttcagcgttt cgaaccggtt
    15001 actgatgcct atactgatag ttaaattcaa gtattctttt acacgttttt gaatgagtcg
    15061 gcaatactcc atgacttttt tgcttgcttc tgcatcatct ttatccattc gataaatagt
    15121 ggcttgcatt tcttcattca aaacgatcgg cagcattcga ttttcctttg gcacaatttc
    15181 cgtgatcatg ttgttgatcg ctaaaagtag caaatcacgc tccccaccgt gactatcttc
    15241 taacagatcg atttgaacca aagctgtata atagcagtca ttttgagaac tataaccaaa
    15301 ttgctgcaac cgctgatcta gttctcgcct ttctactcga tttctaaata aactaagtac
    15361 aaatagcgtt tccagctgtg gcttttgggt aactaagtgt gcacttaacg cttctttttc
    15421 tcctatgatc cgactgactg attgagcgac caaatctagt tctttcccac tgaatccttt
    15481 tgatttaaga ttcagacgtt cctgtatttg agaaatcgga cgggcaaatc tgtccgaaaa
    15541 taagtaggaa agaagaccaa tgagtcctac cagtgttaaa gacactgcaa ctagcccgat
    15601 tctcagattg cggatcattg cgccaattgc actagagtca acttctaatc tgtaaatcca
    15661 attattataa tctgatttca gtactatata cgttttatct ttttctctta tcactttcag
    15721 ctgattgtaa tctagatcca cgtccgttaa tacagttggt tgctctttat tttttactgt
    15781 ctgagtagta aaaaggttgc caacttcgtt ttcaatagaa agtatgtctt ctccactttc
    15841 accaacaact tgttctattg tatgtttctc tatcgtagca attcccaatg catatttttc
    15901 tttttcaaac attggcaaag aaatcaccat ttcgattcct ttgtttttct tttgccaaaa
    15961 taaattattt ttgttattta tgtacttctg ttgatacttt tcaatttcct cttcggtcag
    16021 ttgactcaac gatccattga ttactcccca tttaccagcc aaactgacta aatcataatt
    16081 attatcatcc ataacaatcg tttctataaa atttagttct ttcctgattt cagaataagt
    16141 ggagtaatct gtatatgtca gcggatgctt gaatatgtcc gagaaatttt tggtcgaacc
    16201 atacgtagaa aacgaatatt caatcgttct aattttccat tcaacgttag ttttaacttg
    16261 cctgagcaaa ttctttttgt ctgttaaata actcgattcg atcgattcat aggtattctg
    16321 gtaaatgaat aaactaaatc ctatgacaag tacggctcct aataaaaaca tcggtaaaaa
    16381 tattttataa aatactgtac ttttcttcat tttcttcctc tcctcctttt aaaataaaag
    16441 gctttcattt ttctgtaaaa ttgatactca tctaattaaa tgagcattcc ccgctttcaa
    16501 gaatagcata attaaaaata aaaatccaag taatttttaa cgtgtgcaat cttttcatat
    16561 caaagatcta ttgacttatc gtagttatcg taatatgatg aatgcgttaa caaaaagtga
    16621 aaaagtaagg aaaatgatgg aatggtaacg atcaaagatg tcgctaaagc agctggcgtt
    16681 tctcatacga cagtttctcg tgctttgaat aacagcagtt taataaaaaa tgaaacaaaa
    16741 caaaaaatac gacaactagc taaggaaatg aattattcgc caaactatag tgcaaaaggt
    16801 ttagtgaatc aaaaaaaata tctaatcgga ctatttttct caagtttgca taaaggaact
    16861 tcatcaaatt tcctagcaga ttccattgca ggcatccatt cagtattaga cacaaattac
    16921 agtttatctg ttgaaagtat cgatgttgtt gatttaacag aaatcaacct gcaacgctac
    16981 gatggactga tcgttatgag tcaaagtgat gatgatcagc ctttcatcga ctatctcaaa
    17041 gaaaaagaat ttcctttcgt tgttgtcaat cgtcacatca atgatccagc ggttatcaac
    17101 gtcactgccg atgatgcggc cggtgttatg caggcagtag attacggtat tggatgcgga
    17161 catacgaaga tcgcttatat tggcggaaag aaaaattttc gttcgacaaa agaacgggaa
    17221 aaaggggtat tgaaaagtct aaaaaaagcg agcatccctg tcaatccagc ctatttttta
    17281 acaggagatt acagcttaga aagcggcctc caaaacatgg aatacctatt atcactttct
    17341 gacctgccta ctctggtttt ttgcggcaac gacgacatag cgattggtgc attgagagct
    17401 gtacatttag ctggcctccg tgttccccag aacatttctc tgatcgggtt cgatgattct
    17461 ccagtcgtct cctatctcaa tccgccgctt accaccgtac gtaagccttt gaaagaaatg
    17521 tgtcaagaag gaacaaagct tttactagat ttgatcgaag gcaggacgat cgaacaatct
    17581 aaaattgagc tctccacctt gttgatcctt cgtgagtcga tcaattactt gtaaactaca
    17641 agtaatttta tataaaaatg ttaacgtgtg cataacacag aaaggaagtt tatatgaaaa
    17701 aactgacaaa agaattagtg aaaaaaaacg aagcacctgt aaaagttctt cagtttggtg
    17761 aaggcaattt tatgcgtgga tttattgatt ggcagattca gcagctgaat aaccaacaat
    17821 tgtttaaagg taatgttgca atcattcaac ctttagaaca aggtcttgga aatatgatga
    17881 accagcaaga taatttatat acggtcattt tacaaggact cagcaatggc gaaatcgttg
    17941 atacttccga gattatcacc gtagtagaac aaatgatcaa tccttatgat gaatgggatg
    18001 cttatctatc tctagcagaa aatgacgact tggcctatat cgtctccaat acaacagagg
    18061 caggaatcca attcgtggag actgataatt taacagatac tcccccacag agcctcccgg
    18121 gcaaactgac agccttttta taccgacgtt tcaaattaaa caaagctggc tttaccatca
    18181 ttccttgcga actgattgac agaaacggcg aacgtctaaa agaaatcatt ttacgctacg
    18241 cagaaaaatg ggatttagaa cctgcttttg ttgagtggtt agaaaaagaa aatgttttct
    18301 gttgtagttt agttgatcgc atcgtcccag gttatcctcg cgaagatgca ggtgttttca
    18361 atcaacggca taactatgaa gatcaattga tggtcaaagc agaaccattc atgctttggg
    18421 tgatcgaagg gcctaaagaa ttggagaatc aactaccatt caaacaggct ggcttgaatg
    18481 tcatcatcac agatgatatg actccttatc gtgaacgtaa ggtgcatttg cttaatggac
    18541 cgcatacagc gatggtccct cttgctttgt tggcggaatt ggaaactgta gaagaagtaa
    18601 tgaaagatcc tttattctcc gcatatgttg atcagttatt caatctagaa ttgattccta
    18661 tgctttcttt acctaaagat gaattagcca tttatgctga ccaaatcaaa gaacgtttct
    18721 tgaatccttt tgcccatcac aaattagaag cgatttcatt aaatagtgtt tcaaagttca
    18781 gcacccgtct gcttccagtg ttcaagaagt atatcgaaga acaaaatcag gtaccaccgt
    18841 taatcactgt ttcactagct gcgctacttc ttatgtatcg aggcgatcaa gtaaagccac
    18901 atgatgatga aaagacgata agcgaattta ctgatgcttg gtctgataat ggaacagcta
    18961 ttcctcgatt attgcaaaac gctgcgcttt ggggagaaga tttgtctcaa ataccgaatg
    19021 tgacagatac agttcaagaa atagctgcaa agatcgatca aaaaggtgtc cggtcagtat
    19081 tacaagaaat gaaaggaacg atggtccatg cttgaaaccc tgcaaccaac aatgaaatta
    19141 aatcgacgag acagtgtggt cgtcgcatta acccctattc caaaacaaac acaactgacg
    19201 attgatcagc aaacgatcac cactcttgaa gatatcccgc aaggtcataa gattgcattg
    19261 ggtgatttga aagctggaga caacgtgatc aaatatggct atccaatcgg tcatgtgacg
    19321 acagacgtaa ctgccggtca atggctgcac actcataatg taaaaaccaa tctttctggt
    19381 gaattggatt atcgatatga aaaagatgtc catccaagtc attacctttt tgagaaccga
    19441 acatttcaag gttacttgcg aaaaaatgga aaagtaggga ttcgtaatga tttgttttta
    19501 gtacctaccg ttgggtgtgt gaatggcatt gctgaactga tcgtcaaaca gttcaaggaa
    19561 aaacatccag atctgggaca gtttgaccat attacgattt taaagcatcc ttatggctgt
    19621 tcgcagcttg gaaaagatca tcaaaatact cgagaaattt tagcggacgc agtaaatcat
    19681 cccaatgccg gaggagtttt agtatttgga ttaggttgtg agaacaatac agttcctgaa
    19741 ttcaaaaaaa ttttaggtga atatgatgaa gaacgagtga aatttctagt ggctcaagat
    19801 gtttacgatg agatcgaaca aggtgtggct ctattagaag agcttttaac agcggcggaa
    19861 aatgaccagc gcatatcagt cccgctctct aagttgaatg tcggtttgaa atgcggcggt
    19921 tctgatggtc tatcgggaat aactgctaat cctttacttg gtgcattttc tgactacttg
    19981 attgctcaag gaggcagcac gatcttaaca gaagtgccag aaatgtttgg cgcagaacaa
    20041 gtattgatgg cacgagcgga aaatgaagaa gtttttgact caatcgttga cttgatcaat
    20101 gacttcaaac agtatttctt gtcttacggg gaaccagttt acgaaaaccc atctcctggt
    20161 aataaagcag gtgggatcac tacattagaa gataagtctt taggctgcac gcaaaaatca
    20221 ggaagctctc ctgtcgttga tgtgctacaa tatggcgaaa aaatcagaaa accagggctt
    20281 agtttattgc aagctcccgg gaatgatctt gtagctgcct ctgctcttgc ttcatccgat
    20341 tgccagttgg tcttgtttac cacaggaaga gggactccgt ttggctcata tgtcccaacg
    20401 gtcaaggtat ctacgaatac aactcttttt gaacgcaaag gtcattggat ggattttaat
    20461 gcaggcgtct tattagaaca accaatggaa gtaatcttag aatcgtttgt tcaaaaaatc
    20521 atcgctgtag ctagtggaga agaaacgaaa aatgaacaaa atgacgttcg agaaattgcc
    20581 atttttaaaa acggagtaac actttgattt tcataaaaca gtataaaaag aaagaaggaa
    20641 gatttatgtt tttatctgat gattttttat taaaagacga ttgggcgaaa aagctttacc
    20701 attcctacgc aaaaaacatg cccattattg attatcactg tcacttagat ccaaaagaaa
    20761 tttacgaaaa caacaatttc agcaatctga cagaagcttg gttaggaggc gatcattaca
    20821 aatggcgctt gatgcgagct tgcggcgtgc ctgaagaaaa aatcacagga aatgcttctg
    20881 attttgaaaa atttttagct tggtgtcaaa ccgtaccaaa aattatcgga aatccgcttt
    20941 acagttggtc acatcttgaa ttgaagcgtt tcttcggtat tgacttgttg ataaatgaag
    21001 aaaatgcaga gaaaatttgg acacaagcaa atgaaatttt ggcagctcct gattttcgcc
    21061 gtcgggaaat cgcaaaaaaa tcgaatgtag aagtgatttg tacaacagat gatcccgcag
    21121 acgacttgca ctatcatcag ttgcttgctc atgaagaacc agatttgaag gttctacctt
    21181 cattccgtcc agataaagca ctcaatattg aaaaagaagg atttaatgca tgggtcacac
    21241 tactggaaga agcagctgac caaacgatca ccacctatca agaactgata gaagtcttag
    21301 ggcagcggat agaatacttc catcaacatg gatgtcgtgt ttccgaccac gctttagaca
    21361 tcttacgcta taaagaagcg gatgaaacag tattagaaga gatttttcaa aaagcacgag
    21421 ctaacaaact attatcttca gatgaaatcg atgcttatcg tacagaaaca ctgatacatt
    21481 tgacccactt ctatcattct cataattgga cgatgcagct gcacatccat gcttatcgta
    21541 actgtaatac acaaatgttg gaaaaattag ggcccgatac cggctatgat ggaatgaatg
    21601 atctttcttt gactattcct ctgcaaaaat tattgaaccg tgcagaagaa acggatcagt
    21661 tgccaaagac gatcctttat tcattgaatc cgaatgacta tcctgcgatt ttagctttga
    21721 tgggctgttt ccaaaaagaa cagaatggaa aactgcagtt aggttctgga tggtggtaca
    21781 acgatactcg agctggtatg cgcgatcaat tgacacaatt tgctgatggt agtgctttgg
    21841 ggaattttgt cggcatgctg acagattcaa gaagtttcct gtcctacact agacatgaat
    21901 atttccgtcg tgttctttgt gaatttttag gcgaaatggt catgcgagga gaagcacctg
    21961 aagatgaaca acttttagga agtctagttc aagcgattag ttatacaaat gctaaaaatt
    22021 actttggctt ttttgcctaa ttgattaata gtaacagtaa cgaatcaaaa acaggatagt
    22081 gaaataacgg aatccgttta tccacgtttt agagaagaag acggaccaaa tttgctccgt
    22141 cttcttctct tgctgttctg cttcattgcc tataaacctt tatgaaagaa gagataacat
    22201 gcctactatc catattgccg gtgattctac tgcggcagaa aaagatgaaa acaagcgtcc
    22261 cgagacaggt tggggagaaa aaatctctgc ttatttttca cccgagatcc agatcaataa
    22321 ccaagcaaag aatggacgca gcaccaaatc atttatccag gaaggaaggt tagcccgtct
    22381 agcttcacag tttcagccga atgatttctt atttgtacaa tttggacata acgaccagaa
    22441 aatccaagaa gaaagaggta cgcttccctt cggtagctat ttaaaaaatc tgcagatatt
    22501 ttttgaatgc gcaaaaaaag cgaacgtcca aatggtctta ctgacatctg tgacgcgacg
    22561 agattactta gaaaacggaa cattgaatcc agatatactt ggagactatc caaaagcgat
    22621 gcgtgcattt gctgagaaac accatattcc tcttttagat gtgttctcaa gatcacaaga
    22681 attgttccag accttctcaa aagaagagac aaaaaaattc tacctgcatc ttatacctga
    22741 tacttgtaaa aattacccag aaggactaaa agacaatacc cactttagtc cagaaggcgc
    22801 tgataaagtt gcccgaataa ttgttgaatt gataaaagaa tcccgtccgc ctcttgctaa
    22861 ttatttacaa aaaggagttt gagatgtttc cattaaattt aggcatccgt gcccacgatt
    22921 tagatgttcg aaatcgtgaa gaaatcgttc aaaaagtatc acagcttcac ttgtcccata
    22981 tccaatttgc accacaaaaa gcatttcctg aacaacttaa attaactgac atgacacttg
    23041 ggagtgctgc ctattttggt gaatacttcc aaaaaaacaa tatcgaactt tccattttag
    23101 gatgctatat caacctatcc agcaaaaatc aagaagttcg tgcacaagca ttggcaactt
    23161 tcaaacagca aattgctctg tgctctgcct atcaagccaa gatgattgct acggaaaccg
    23221 gtagtgtctc tgtcggttac acaaaagaaa attttactga agaagcttat cagatcgcca
    23281 gaaattctat cattgaatta gtcgctcatg cagaaaattt tggcgtaact gttgctgttg
    23341 aagcagggat caatcatcca atctataact atcagttagc taaacgttta atcgatgaag
    23401 tagcttcacc aaatttaaaa atcattttag attgtgcgaa tttgatgcat aaagaaaatc
    23461 atgctgatca ggaaaaagtg atccgaggtg ccttggacaa tttacatggt tatattacag
    23521 cgcttcatct caaagactat atcatggaaa atggaaagat ccgcatggta cctgttggca
    23581 agggctgttt agatttccgc ccggtactgc attatatcaa atatgagcgt cctctaatgt
    23641 acgccactct tgaagctact cctgagattt atgttcctga agcaatagaa cacttgcagt
    23701 ttatttacca agattgttaa ggagaagatt atggaggaac gaatacagaa aagttatcaa
    23761 aaatatcatg caaatgcttt tcagacattg ctgcatcttt atcagggaaa ttattggcgt
    23821 tttgccatgt caggactctt ttttattatc aaacatcttc catcttggtt aatgccgatc
    23881 gctattgcca atgtaatcaa tgcagcttca tcgaaagatt cttctcagtt gcaggccatt
    23941 tatttcaacg cttttttgat ggcttgtctg attggtcaaa atatattgac gaattatttt
    24001 catgtaaaat accatagcac ttcgatccgt caagtagaag ctggactaag agcgaccctt
    24061 atcaagaaaa tccaagaact atctattcct tatcaaaaag aattgcaatc tggacgaatc
    24121 cagtcaaaga tcatccgtga tgtagaagct atccaaacgt tgtcctctca agtatttgtc
    24181 agcggattaa atatcgctgt caatttattc gtagctttag gtatcacgct ttataaaagt
    24241 cctgttgttt tcatgttttt cttattgact gttcctctcg ccgcattcgt tactctcttt
    24301 ttccgtaaaa ggatcagaca gtccaactca gacttcaggc aagaaatgga agagacttct
    24361 gcaaaagtga tcgaagtgat cgaattagca ccgattgctc gagctcatgg gttagaaaaa
    24421 cacgaaacaa ctcgcttaaa taagcatttt actcaaatct atgaaaaagg attccactta
    24481 gatatcctgc aatctgtttt cggatcagtc agctgggcta gttttcagat atttcagctg
    24541 atttgtttga ttttcactgg gatattagct ttacaagggc gcatccaacc cggcgatgtc
    24601 gtgatgtatc agacgtattt cacgacgatc gtcaattccg tttctggaat gatcacgctg
    24661 attcctacga tttcaaaagg catggaatct atcacttcta ttggcgaact gttgattgct
    24721 ggcgatgtag aaacttatca cggtaagaaa aaaatccaac atttggatgg aaattttcgt
    24781 tttgaggatg tttcttttct ttatccggac tcactcaaac cgattatcga tcatttttct
    24841 ctagaggtga aagctggaga aacaattgct tttgttgggc catctggctc tggaaaatct
    24901 acactcctta acttattgat tggatttatc cagccgactt caggaaaaat ttttctagat
    24961 gatcagcctt tggatgaact ggatatgcga agtgtgcgaa attatttagc cgttgttcct
    25021 caaaccactt tgttgttctc cgcttcgatc aaagagaaca tcacttatgg cttgaaaaac
    25081 gtatcaaaag aacgtttaga tgaagtcatc gaagctgcgc aactttcttc actgattgac
    25141 cagcttcctg atggtctgga taccttagta ggcgaacatg gcaacaagct gtctggtggc
    25201 caaaagcaac gtatctccat tgcacgagcg ttgatacgtc agccaaaaat cattttgcta
    25261 gatgaagcaa cctcagcttt agataaccag tcagagaaaa aaatccagca agccctgaat
    25321 tacctgacag aaacacccac tacttttatt gtggctcatc ggctttcaac gatcaaagag
    25381 gcagataaaa tcgttgtgat cgatgaagga aaaatcgttg aaataggtac ttacgaaaaa
    25441 ctgttagctc aaaaaggcta tttctaccgc ttgaaaaatg aatgacaaaa aataggagct
    25501 atgacaagac ttttgtcgta gctcctattt ctgaataaac ggtgttctcc tgccaactcc
    25561 tcggtcacaa gtcacaatag tcatcaaaca tgagaagctg ttttttgaaa ttgttccttg
    25621 taactcagag ttaaacggta ggctcacgac ctcttggtaa atggtgttca agagacagcc
    25681 tatcggcaat aagaagcaat tttgtcatcg ctcaaggccg aacgtctctt tcacaccctc
    25741 tgttgtttca taaaatagtt ttattcgctg taaaggtcgc gaactggtgt catgatgata
    25801 cggttcaagt cattgatgat tgtactgaag ccttgctctt tttgcatcaa gtcattgatt
    25861 acttcttctg attggatttt cacagccatt tcttgtgctt tcattgcatc ttcgtcgctg
    25921 aactcttgtc cactcatttg tttttcttgt aattcgattt gcatcgcttg gaagtctttg
    25981 aacagtttgt gtgcttcttc gtttgcttgt actttctcgt acgcttcttt caacgctttg
    26041 aattctggta attcacggat ctcacgttcg atttgattcg cgctatcgta gatgtttgac
    26101 atgttatgcc ctcttttctt ttagtagtta ctctctattg taacatgggg ttattcgttt
    26161 tcaaaggggc tactctcctt gatatttccg ccagaggtct ttagccgctt caccaattcc
    26221 ctgaacgcct tctttcacca tatcgccgaa gtttttcagc ccttcttttg cttgttcacc
    26281 atattgattc aagttatctt gccaatttcc agactctcca ttagaatttc ctgtgtttcc
    26341 aacttgatct gcagctacca cttgtcctcc tgtggcatag gcatctgcta cactaaatcc
    26401 tgtttttgaa gtatacggaa ggatgccttc tgccgctgat ttgaagactt tcccgacaac
    26461 atttccactt gtcccttcca aatagtgcag cttgctggat tcttcgtaac ccatccatgt
    26521 cgaaatcact acgtctggcg tgtaaccgat catccattgg tcatttgctt ttgtggcatc
    26581 gaaattagtt tctgtggttc ctgttttccc tgctatcgta taacctgcag gattcgcagc
    26641 agccgctgtt ccatttgaaa atgtaccaag aagcatgctg gtcatttcat cggctgtttc
    26701 ctttgatatg acctgttttg gttttttgtt tgtgttatcg acgatcaccg ctccagtcga
    26761 atcaacgatt ttcgtgataa gatgcggcgt atacatctga ccatcattgg caaatgcact
    26821 gtaagcaccc gccatgatca atggagatac tcctttttcc agtccaccaa gggctaagcc
    26881 ataatactta tcagattttg ctaaaggcag gccgaattct tctgctttat catatccttt
    26941 ttgtaaaccg atctcatgca aaagccatac agtaggcaaa ttcaaacttt gtgcaacagc
    27001 ttgatacatc ggtacttctc cttggtatgt cccgtcaaaa ttatgcgcat cgtaataact
    27061 ttgcggttcg tctttcaaga tactggaagg cttgtatcca gcttccagtg ctggtgtata
    27121 tacgcttaat ggtttgatcg ttgatcctgg tgaacgacgc atctgtgtag caaagctgaa
    27181 tcctctaaag acatgatctc ctcttcgtcc tactagtgct tgtacaccac ctgtattcgg
    27241 atctaaagct actgaagcag attggaccat ggcaccatct gaagcatttg ctgggaataa
    27301 tgcactgttt tgataagtag cttctaattg cttttgataa tcctgatcta aagctgtata
    27361 gattttatag cctttattca tgacatcttc ttcatcaaga ccatactcgt taactgcttc
    27421 atcgatcact gcatcaaaat aataaggata acgataacca gaatctgaat tatcgtatgt
    27481 gtcattaaga tacgcgctga tatctgtctg gctttctgct tgttcttgtt cttttgtgat
    27541 ttttccgttt tcttccatta cacttagtac tgtgtttttc cgatcattcg cattttttgg
    27601 gtgatcgatc ggattataaa taccaggacc tttcagcatt cctgccaaag tagcagcctc
    27661 agacagcgta acattcgttg catctactcc aaaatacttt ctggaagcgt cttggacacc
    27721 ccataccccg ttgccaaaat aggcattgtt aagatacatg gtcaagattt cttctttgct
    27781 gtacttcttt tcgatctcga ttgccaaaaa taattccttc gcttttcgat caaacgtttg
    27841 gtctaatgtc agatacgcat ttttggcaag ctgctgagtg atcgtacttc ctccgccccc
    27901 tgatgttccg ccagacaaga ccattcggac tgctgcacgg gcaatccctt tgatatcaaa
    27961 cccgtgatgc tcgtaaaaat tcctatcttc tgtcgagatt actgcatctt ggatataggg
    28021 agaaatcgcg tttaattcta catatgttcc tttttgggcg tacagtgtgc cagcttcttc
    28081 gtttttctta tcataaatga ctgtcgattg gcttaatcct gattttaacg tttcgacatt
    28141 tgcttgtttt gctaaaataa agaggtagat acttgtcact aagacacaga tcaaaccaat
    28201 cagcaaaatc aatttgttca catgatattt tttccagatg cgctttcgcc atcgatggaa
    28261 ttgtccgaga tatggtctga tccaacgcca aaaactgatc aaagcagctt ttatcttttc
    28321 taaaatgctt tgaaaatcca tttgcttctt ctcctgtcta tttgattcaa tcgtcttatt
    28381 ttaccatagt gaaagagtgt tttcttcctg cttaagttgt agttcaatat gtttttttac
    28441 gttagtgcaa gtagagtaac ataagaatga acagaaaaat gtaagttttt tcttaaatat
    28501 gttttaaaaa tggtacaatt agtctgcgat tgcactgaaa ggagtacact tgtgaaaatc
    28561 acgatcactt tacctatgaa ccatcctgaa acaacaattc gcgacttgct tgaaaaggaa
    28621 tggttagttc ctagaaaggt tcgacacttt ttgcgtatac gtaaaaacgt ttggatcaat
    28681 caacaacctg ctttgttcca tcatgaagta aagggcaatg accagatcac attgttattc
    28741 gaagaaacag attataatta tcaagaagtt caattaggag atgcgaagca catccgtgtt
    28801 ttatatgaag atgagcattt gattatagtg gataagcctg caggaatgaa gactcatcca
    28861 aatgaaccga cagaaaacag taccttactc aatcatttag ctgcttatct cgacactaaa
    28921 cagcaacgac cttacgttgt ccaccgcttg gacaaagaaa caagcggtgc cgttttattt
    28981 gcaaaaaatc catttgtctt gccgatactt ggaagaatgt tggaacaaaa aatgatctat
    29041 cggagatatc aagccatcgt atggggagaa attgccaaag atatgaccat caccaataaa
    29101 attggacgag atcgccatga tcggagaaaa agggtcgtag atgataaaaa tggtcagagc
    29161 gccttgacac atgtcactgt caacaaagta ctttctgaac aaacacaagt ctattgtgtt
    29221 ttggaaaccg gacgtacaca ccagatcaga gttcatttag ctcataaggg acatccgatc
    29281 gttggagacc ctctctacca aaatagaaca gctgaacgac tgatgctcca tgcattagaa
    29341 ctgcacatga tccatccatt tactcaagaa aaaatagtcg gtaaagcttt acctggatta
    29401 tgggaataga aataaaaaag aacagagtct tatcagcaga taatgataag actctgttct
    29461 ttttgtgtaa tttgtctgct tacttttgat gttcgtgttc tgctaacagc aaactaccga
    29521 taatcccact ttcattcggc agtccccaac gaacgatata ttcacttact tgaggtgttt
    29581 ccatataacc acccatcaat tcaacaaatt gctgacggat tttttgaagg agatgatcct
    29641 gattcattac cccaccgcct aaaataatct tttcaggtgc taacgtcaac gtatagttga
    29701 tcagtgcttg agcaatataa taagcctgaa tagcccaaac aggatgatct tgcggcagat
    29761 cttgcccttt gatccctgtg cgtgcctcaa tagacggtcc tgctgctaat ccttctaaac
    29821 aatctttatg ataaggacaa gtaccttcat aatggtcatc tggatggcgt ttcacccaaa
    29881 tatgtcccat ttcaggatgt gcgatccctg aaaaaatttc ttcattgatc acgacacctg
    29941 caccgattcc tgttcccacg gtaaggtaaa tacaactatt ttttccttgt gctgctcctt
    30001 gcttcaattc cccatatgca gcagcattga catccgttgt ccaagcagca ggaatattgt
    30061 agcgttcctt gattgtgcca agaaaatcga attgtgccca cccttttttg ggagttgcca
    30121 aaacgtatcc gtaattatct tttgttttgt cgataccaat cgggccgaat gagccaatcc
    30181 cgattccctt caattcataa cgatcaaaaa attcaaatac ctgatccaat gtttcttctg
    30241 gtgttgtggt agggatactt aatttttcta aaatttctcc accatctgaa accgcacaca
    30301 caaattttgt tccgcctgct tctattccgc catacattcg ttttcctcct cgaatccgat
    30361 tgtccgaatc tcataaggtt ggattattgg gacaaccgct tgcttcgttg gttcttcaag
    30421 cagattcaat atgacagttt ttccattgtc tttagttatt tccaattttt ctaaatgact
    30481 agacatattg aaacctctta ctactacttt atcactaaac ttgctgcgtt tcaaagctgt
    30541 aattgcaaac gtttcacttt ttatcgttaa atattgttgt tttgaaatca atgttccttc
    30601 atgatgtttg atttgttgag tggaaaaagg aatctgtgct gcgtatgcat gcaaataagt
    30661 agagaatttt tcttctggtc catgtagttc aatgctgtaa ttgaaccgat gctcacctag
    30721 acactgtgct tctggtgttg gaaaatatcc ccaatcgcct agttctccca cactgcgaag
    30781 tagcgtcact gcgatttgtc cgtcttctgt tacttcatat tcattcaaac caaagtttcc
    30841 gactgttaca ccgtactctt catcatgaat attgacaaat gcttgctgat gttgcggatt
    30901 cgtggggttt tcccaacttt tagacacatg gtttgggcgc ttcaccactt caaaaatact
    30961 atctgcttcg tgatgttcca catgtaactt tgtaggaaac aagacacgta agcgatgatc
    31021 tttcatctga ttgtcgagag tcgtttcaaa gtcgattttt ttactatctt ttctgattgt
    31081 catgattgtt tttatttgaa ggattcgttt ttctttggat cgttctgctt ttcgataacg
    31141 aaattccaca accatctgct gttctttttc taaacgctcg tctgcagaaa cagggatttc
    31201 catttcctgt agaatactta tttttgctat ttccggtgta tctactaata cttttacttc
    31261 agagttttct ttgttactgg ataggattgg ctgatcacag aaaggttgtt taaagatata
    31321 ctcatttcct atatcgccga tatcttcaaa aatatgcaga ttattcaact ttcgtttgtt
    31381 tttgcgatct tccattgtaa tggtaccatt tttttcaatc gtcaaatgta gagggccgtt
    31441 ttcgatgatt cgtccactct gatgaatcat tgtttccttt tcttctgctt tcgcttcccc
    31501 ttctacaagc gcgaatgttt cccaagaaaa tgctggcatg ttttctaatg gtaaagtcac
    31561 tttgatcatt cttgccatat atggcacacg gaaacggtct ttcggcaaat cataaccaaa
    31621 ttggacagtt tcttcagata aaatagctgg tatagtggcc ccactttttg tttctacatg
    31681 atacttacgt ttaggcaaat tttctaactc ttgatatagt tgttcaggta ttccttcagc
    31741 gaatcttttt ctttctaatt cgatggttat ttctgcttca ccagttttat ccattcctgc
    31801 agtatttaca atgacaaatg gaaagctgtc ttttgggaat ccggtcgtat cgattgctgc
    31861 ggtcagctgt tctaaggaat cttgtgcaag atactttcca acttcatctg ctttttcaaa
    31921 acgaggtatc atttcccgat ggacagaatc gactgaacaa ccgcaaatac tgtcgtgagg
    31981 atgattttgc attaatgtct tccaagcata atctaattga tcatggggat agtttccact
    32041 aacttcataa gccatcgtcg caagtggttc tgtaatattt tctagctgtc gctggacctt
    32101 ggtattccat tgttttaagt aaacccgagc agatgctgta ttggctaaag tataccagcc
    32161 atccgtttct tgacttgtca attctccttc tactgagcct aagtcttctg gcacatcttt
    32221 ttgaactgct tccagatagt cagtaaaatt agaatgaata aactcgtaat ctggaaacag
    32281 ttcatttgcg agatggattg cttttgatat atctttttgt accggttgat gatcaacacc
    32341 attcatcatc aataagtggt tcgtagaggc atattgttct gcatccgcta atttttgctt
    32401 ccaaaaggca agagctgctt ctttttctac tggaatctca ttcccgttgc tataccaatt
    32461 ggcaaatagc agaccaaaga ttgctgtttg atcaggtcct ttccaccaca tctctgagta
    32521 ttgggaagaa tagttttctg cttccaaaac ttgattatca aagccaattg gttttacacc
    32581 acggccaaac gctgctgctg aaataccagc ttgtttcatt aattgaggcg tctgtcccat
    32641 atttccaaat gtatcgggaa aatagcctaa catgacaggg gttccccatt tacggctttc
    32701 ttccatgcca atcagcatat ttctcacgtt cgattccgag ctgataagaa aatcatcttg
    32761 caagatataa aatggtccaa ttctcaattt tccttcattg attgcttgtt ggattgcctg
    32821 tcttttttct ggccttactt gaagatagtc atctaaaata atcgtttgcc catccaaatg
    32881 aaaactgttg aaggacggat caacttcaaa tagctctagt agatcgtcta tcaattcaat
    32941 cagtcgcatg tgatgctgtt cgtaagccat gtaccattca cgatcccagt ggctatgaga
    33001 aatgatatat actttctttt tcatttacga tacctcctac ttttctactc taatatcaaa
    33061 gtaatccatg actaattcgc aaaacatcat atttgcccaa gaaaaccatt ctctcgtata
    33121 attttcagga ttgttcacat cgaatccttc gtgcataagg tgtgttcctg cgtcagttgc
    33181 tacaagtaaa ttcaatatcc gctctttttc agatttgtct gacgttgtca ttccttccat
    33241 agctaatgca atcggccaaa cgtatttttc tggcgtatgg gaggatccaa ttccttttgc
    33301 gtactttcct tcatagaaat atggattttc tttactcaac aatgttcttc ttgtttgcag
    33361 ataatcttcc tcttgttcag aacaatatcc caagtaaggt gcggcgatca gattgggcac
    33421 attactgtca tccatgactg tggcgtttcc cattccatct acttcatatg cataaatcgt
    33481 ttgccctttt tgattaaccg ttcgtccgtg attctgaatc ccctcttgga tctctttctt
    33541 caatttctgt gtttgctgta caatttcttt atcatcgagt atcgtttgaa aaatttcttc
    33601 cacataacct aacacgacca ccgcaaacat attggatggt accagatatc cataacggca
    33661 agtatcatcg ctaggacgga aaccagacca tgtcattcct gtaaaagctg tttttgcacc
    33721 tcgcccgtca ttgatcagcg tatcttcttt tcttgtcgtg tctcgtacaa atgtataagg
    33781 agagtgttca tgatcttgct ctgttttgaa cacgtccaag atttttttga taccttcaat
    33841 aaaagattga ttgaattgat cagtttttcc tgtatttttg taaagaagat aggccaactg
    33901 tattgggtag cataaagaat caatttcata ttttctttcc cagatccaat cgttcatttt
    33961 tgtatgatct gtttggtggc cagcaccgtt agcttcttcg ttgaaggcat tcgcatatgg
    34021 atcgatattg atataaaaaa attgcttttt gactaacccg ctgatcatgt cagctaattc
    34081 ctcatcttct tttgcaatca ctaaataagg acgaacttgt gcagtagagt ctcttaacca
    34141 catcgctgga atgtctcccg tcaataaaaa ggtggttccg tcattttgct ttttgactgt
    34201 tgtcaacaga gtattggcaa atgctgctgt aaaattcttt gcccagtccg catggatatc
    34261 cccacatttt tgtgtgatat cttccataaa tttctgcacc gattttggta tatctttata
    34321 agccactaat aaaaccttct ttctatttga tatatcttta aagattatac ttcatacagc
    34381 caattatgtc tacgctttca aaaaatatct ttttatttac tttttcatcc attatggtat
    34441 tatttgaata tgatatatca ttaagaggtg tttatatgaa tcaaccattg taccagacaa
    34501 tatttaatga tttgcaaacg gctattttaa ctggtgaatt acctgtagac agccaactac
    34561 caactgaaaa agaactttca cgtacctata aagtaagcag aatcacttcc aaacgtgcat
    34621 tgactgaatt agagcaatta ggacttattt atcgcgttcg cgggaaaggc agtttcgtta
    34681 aatccgcttc tccggaacag attcttgctt ctcctacaaa aacacgacgg attctgtttc
    34741 ttcttccata tgtcgctgat ttgtctgttg gtgattttag caagggattg aaccctgtga
    34801 tgcaagataa acagattgat gtcatgatga cgacgcttga ctttctacaa aataaaacag
    34861 caaaagagct aatcaatgaa tttgacggat tgatttatta tgctcttgat acagaacaac
    34921 atcttgactt actttttgag ctttcattga aagaattccc tgtcgtcata ttagataaaa
    34981 aaatctatga gttacctttt cctaccgttc tttccgataa tttccaaggc ggtgcgcttg
    35041 ctgcctctta tttgatcgaa cagggacatt caaaaatcgc ttatttgttt ggtacgcaga
    35101 ctcatccaca atccgttcga cagcgttacc ttggttacct tgaagcattg gacaaagctg
    35161 gtttgacttt ccacacttca ctggatgaca aaagcgcgac attagatgaa ttgctttctt
    35221 atatcactaa gtatgaagta actgcttttg tttgtgaaaa cgatgttgtc gctatccaga
    35281 ccatgaatct cttgagacag catagttatc atatccctga agatttttca attatcggat
    35341 ttgatgatat ccaagcagca gctcttgttg acccgccact gacaaccatc gcacaagatt
    35401 ttgaacagtt aggtaagctt gcgggagatg ctttggtcac ttggttagag acaaaagatc
    35461 gaccatccga tagtaaattt ccagtttcat tcatcaaaag acaatcaaca aaggagaaat
    35521 aaaatgaata tcggtcaaat agatactaga catgcaacag cgaatcagcc aaatttctct
    35581 aatgggaact gccagcctta tactggcgtt ccttttggga tgaattattt tgcaccgcaa
    35641 actacggatc aaaacggcag ctggtggttt catcctgatg accgcgtttt tcaaggctac
    35701 cgtcttaccc atcaaccaag tccttggatg ggtgatttca gtcatatgct gtttacgccg
    35761 atcaatggaa aactacagga gaacaccctt ttccatgctc aaagttctta ccgcccagaa
    35821 gaaagtatat tttgcccgac tcatctgtcg atctgtcaat tacgttatgg catctgttct
    35881 acattgatac ctagcatgta tggcggaatc ttatctattg attacagcaa aaatgacagc
    35941 ggtttacttt tatcctttcc gggacgccat cagctctttg ttatagatcc ttacacagtg
    36001 gaaggaaaaa tcacacattt tgctggttca gaagatcctg atttttcttt ttattttata
    36061 ttgagatttg aatatccttt aacaattgat gagttagctg tttccaacaa aaatagcgac
    36121 tcgatcccgt tgtattttga acagacaaaa aaacaaacta tccgatttgg gacatctttt
    36181 atcagctcgg aacaagcagc ttataacctg gaactagaac aaaaccaaag caaagagact
    36241 taccttgctc acagtcaaga acaatggcag tcctattttg atcgtataca gctcacacac
    36301 catgatcaac aacaattgcg gacgttttat cataatttat atcgggtgtt tttatttcca
    36361 caaacatttt atgaaattga tcctagtggg caaaaaatcc actatgatac gactagtcga
    36421 tctataaaac ctggtgttct ctatacaaat aatgggtttt gggatacgta taaaacggtt
    36481 tatcctcttt attctttgat tgctgtagaa aaatacgaag aaatgctgga aggttttttg
    36541 aacagctata gagaaagtgg ctatttgcca aaatggctgt ctcctgatga acgtggactt
    36601 atgcctggga cattgatcga tgcggtcatt gcagatgctg ctgtaaaaga tatccgacga
    36661 gacttgatgc ctgaatttct aacggcaatg gaaaaaggtg ctacggttca aagcaaacat
    36721 ccaaattatg gacgccaagg aacagaagat tacttgacat atggctatgt tcctaatcac
    36781 taccacgaat cagtcaatca cacattagac tatgcttata gcgatttttg tattagccaa
    36841 gttgccaagg tactagaaga agaggaaatg acgaagaaat atcagcagca atcattgaac
    36901 tatcaaaata tctttgacta tgagtcagga tttatgcgtt caaaagataa agatggcaag
    36961 ttcagagaac cattttcagc taatcgttgg ggacaagatt atgcagaagg aagtgcttgg
    37021 caaagcagct ttgctgttta tcacgatttt tcaggactga tcggaaaata tggtggcagt
    37081 gagagatata aagaaaaact cattgagctg tgcaatcagc ccccaacgtt tgacccagga
    37141 ggatatggtt ttgagatcca cgaaatgagt gagatggccg cgatagaatt tggacaatta
    37201 gctatttcaa accagccaag ttttcactat ccttacttgt tcagttatat aggacaacct
    37261 gaaatggcac agccactgct taaacagttg atgactcaga ccttcgacga ttctccaatg
    37321 ggttaccctg gagatgagga caatggaagt atggccgctt ggtatatctt caatagtctg
    37381 ggattttatc ctgtcacgcc tggaaccggt gaatatgtta tcggtatgcc attaattgac
    37441 aaggctgttt tgcttttgtc aaatggaaag gaattgacga ttgaagcaac gcctaatcgg
    37501 ccgcagcaac aatttatcca taaaatcaaa cggatggaca aagaatatac gaaattatat
    37561 tttacccatc aagatttgct gaaaggcggc acgatctctt accaattagg gatcatccct
    37621 caccctaaga aatatcaagc aaaagatttg cctttttcct tatcaaacta taattaacaa
    37681 gaggttgtga aaaagctgtc ctgcatcaag taataagaac agccaagcaa aa
//
LOCUS       DAPBCF010000022        37310 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.022, whole genome shotgun sequence.
ACCESSION   DAPBCF010000022 DAPBCF010000000
VERSION     DAPBCF010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.022"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..97
                     /locus_tag="RD508_001412"
     CDS             <1..97
                     /locus_tag="RD508_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7736022.1"
                     /translation="ILGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
     gene            complement(127..1443)
                     /locus_tag="RD508_001413"
     CDS             complement(127..1443)
                     /locus_tag="RD508_001413"
                     /inference="COORDINATES: protein
                     motif:HMM:NF014437.1,HMM:TIGR00826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7736023.1"
                     /translation="MRDDTKVDKAGLENLEDVKGTFNANGQFQVVIGPKVADIYEEVI
                     SQSGLSGANKEDVKKVAAELNLNWFQRAVKILGDVFVPILPAIVTAGLLMGLNNLLTN
                     PGIFFEQSLIEVYPNIADVADMINLIANTSFQFLPALITWSTVKYFKGNPLLGIVLGL
                     VFVHPDLMNAWNYGQAVTTGDIPHWTIFGLSISKIGLQAQVLPALVSGYVLAKTELFL
                     KKRVPETIQLLVVAPVAILFTSVITFIIIAPITIAIGNTIVAGIVWLFQKVPFIGGFA
                     YGIGLAPLVVTGMHHAFLPVHIQLMANGGDYIWPIGVMSSLAQGSAAIAMNFLIQNKK
                     LKGVGLAAGLSAYMGITEPAMFGVNLKYKFPFVVSILTSGIIGGFMASQHVIATSVGI
                     SGIPGFLSIPFEFWPIFFICMLASCVVSFGATYLYGKNKVLLQSFK"
     gene            complement(1535..1837)
                     /locus_tag="RD508_001414"
     CDS             complement(1535..1837)
                     /locus_tag="RD508_001414"
                     /inference="COORDINATES: protein motif:HMM:NF025668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III-like domain-contianing
                     protein"
                     /protein_id="HDT7736024.1"
                     /translation="MTTTVSNKGSRDGYEVVQLYIGAQYGRYIRPTKDLVAYKKVFVK
                     SGDSVTVSFELTNKDFKYYDEEFNEIIDDGAYWIMVGNDSSQALTNKEEIEVRINE"
     gene            complement(1895..2146)
                     /locus_tag="RD508_001415"
                     /pseudo
     CDS             complement(1895..2146)
                     /locus_tag="RD508_001415"
                     /inference="COORDINATES: protein motif:HMM:NF014026.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 C-terminal
                     domain-containing protein"
     gene            complement(2990..6139)
                     /locus_tag="RD508_001416"
     CDS             complement(2990..6139)
                     /locus_tag="RD508_001416"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HDT7736025.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLAIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PDKTKGLIVTFRKPATMEKNVEDATKLYSKAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYLPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(6152..7369)
                     /locus_tag="RD508_001417"
     CDS             complement(6152..7369)
                     /locus_tag="RD508_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDT7736026.1"
                     /translation="MSNDTQPEIRFPGFTDDWEQRKLGDFVVDYVEKTSVQNQFPMLT
                     SSQQKGIVLQEDYFANRQVTTENNIGYFVLPRGYFTFRSRSDNDVFVFNRNDIIDRGI
                     ISYFYPVFTLKSADSDFFLRRINNGIQRQLSIQAEGTGQHVLSLKKFKNIVAMFPSEE
                     EQQKIGTFFKQLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWE
                     ERKLGELGKTQSGIGFPDAEQGGSEGTPFFKVSDMNNIGNEYEMRNANHYVSNEQIER
                     KKWKPIKDVPAIIFAKVGAAIMLNRKRLVTSPFLIDNNTMAYLFNNTWDIYFGKILFE
                     TINLPRYSQVGALPSYNSSDIENISVKVPVKDEQQKIGTFFKQLDDTIALHQRKLDLL
                     KETKKSFLQKMFV"
     gene            complement(7359..8954)
                     /locus_tag="RD508_001418"
     CDS             complement(7359..8954)
                     /locus_tag="RD508_001418"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HDT7736027.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKKLLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            complement(9464..10246)
                     /locus_tag="RD508_001419"
     CDS             complement(9464..10246)
                     /locus_tag="RD508_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736028.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(10311..11147)
                     /locus_tag="RD508_001420"
     CDS             complement(10311..11147)
                     /locus_tag="RD508_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7736029.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(11165..12574)
                     /locus_tag="RD508_001421"
     CDS             complement(11165..12574)
                     /locus_tag="RD508_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7736030.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(12588..14411)
                     /locus_tag="RD508_001422"
     CDS             complement(12588..14411)
                     /locus_tag="RD508_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7736031.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(15254..15580)
                     /locus_tag="RD508_001423"
     CDS             complement(15254..15580)
                     /locus_tag="RD508_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736032.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(15626..15988)
                     /locus_tag="RD508_001424"
     CDS             complement(15626..15988)
                     /locus_tag="RD508_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDT7736033.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLEMSMY"
     gene            complement(16025..16240)
                     /locus_tag="RD508_001425"
     CDS             complement(16025..16240)
                     /locus_tag="RD508_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7736034.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPMNELFSDVFNKVNS"
     gene            16367..16702
                     /locus_tag="RD508_001426"
     CDS             16367..16702
                     /locus_tag="RD508_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7736035.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(16778..18775)
                     /locus_tag="RD508_001427"
     CDS             complement(16778..18775)
                     /locus_tag="RD508_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736036.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(18873..19148)
                     /locus_tag="RD508_001428"
     CDS             complement(18873..19148)
                     /locus_tag="RD508_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7736037.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            19381..20115
                     /locus_tag="RD508_001429"
     CDS             19381..20115
                     /locus_tag="RD508_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7736038.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINVIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            20154..21296
                     /locus_tag="RD508_001430"
     CDS             20154..21296
                     /locus_tag="RD508_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7736039.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(21391..22782)
                     /gene="sufB"
                     /locus_tag="RD508_001431"
     CDS             complement(21391..22782)
                     /gene="sufB"
                     /locus_tag="RD508_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HDT7736040.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSASSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(22787..23257)
                     /locus_tag="RD508_001432"
     CDS             complement(22787..23257)
                     /locus_tag="RD508_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HDT7736041.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVQDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMKNDGTAAFHHYHKEEE"
     gene            complement(23244..24479)
                     /locus_tag="RD508_001433"
     CDS             complement(23244..24479)
                     /locus_tag="RD508_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDT7736042.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPFVYLDNAATTQKPKQVLQSLAH
                     YYEHDNANVHRGVHTLAERATHEYEQAREKVRAFIHAEETAEVLFTRGTTTSLNWVAR
                     SFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIDLTEEGFLDMEDAAKKI
                     TNKTKIVSIAHVSNVLGVINPVQELAELVHENGGVIVVDGAQSAPHMTIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIAFGHAIDYLQELGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTHDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(24476..25762)
                     /gene="sufD"
                     /locus_tag="RD508_001434"
     CDS             complement(24476..25762)
                     /gene="sufD"
                     /locus_tag="RD508_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HDT7736043.1"
                     /translation="MKEKNWLDYLNAVNDFSLSKGEPDWMRTFRQDALTKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMDEDQLTALHVAFMNSGIFLYVPKNIVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKVPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(25775..26545)
                     /gene="sufC"
                     /locus_tag="RD508_001435"
     CDS             complement(25775..26545)
                     /gene="sufC"
                     /locus_tag="RD508_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HDT7736044.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFNGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEA"
     gene            complement(26742..27590)
                     /locus_tag="RD508_001436"
     CDS             complement(26742..27590)
                     /locus_tag="RD508_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDT7736045.1"
                     /translation="MKKKIFGLAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIALEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIAENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(27614..28300)
                     /locus_tag="RD508_001437"
     CDS             complement(27614..28300)
                     /locus_tag="RD508_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7736046.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(28293..29327)
                     /locus_tag="RD508_001438"
     CDS             complement(28293..29327)
                     /locus_tag="RD508_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7736047.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(29390..29646)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(29722..30060)
                     /locus_tag="RD508_001439"
     CDS             complement(29722..30060)
                     /locus_tag="RD508_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HDT7736048.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(30062..30418)
                     /locus_tag="RD508_001440"
     CDS             complement(30062..30418)
                     /locus_tag="RD508_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HDT7736049.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(30424..31611)
                     /locus_tag="RD508_001441"
     CDS             complement(30424..31611)
                     /locus_tag="RD508_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDT7736050.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYFYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPARGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVVGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(31802..32647)
                     /locus_tag="RD508_001442"
     CDS             complement(31802..32647)
                     /locus_tag="RD508_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7736051.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YPLPQLMKHLIKRFPKVHFEIEIANSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            32881..33846
                     /locus_tag="RD508_001443"
     CDS             32881..33846
                     /locus_tag="RD508_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HDT7736052.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            34346..35389
                     /locus_tag="RD508_001444"
     CDS             34346..35389
                     /locus_tag="RD508_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HDT7736053.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGIKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(35451..35915)
                     /locus_tag="RD508_001445"
     CDS             complement(35451..35915)
                     /locus_tag="RD508_001445"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDT7736054.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQQILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            36160..37107
                     /locus_tag="RD508_001446"
     CDS             36160..37107
                     /locus_tag="RD508_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7736055.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDVDSVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
BASE COUNT        10894 a         7730 c         6385 g        12301 t
ORIGIN      
        1 cattctagga ttatataaga aaacccgaaa agaaggcact ctcttcgggt tttcggtctg
       61 tactgaaatc aaggtattat tgggaatccc agcttaaatc atagataccg taagggattt
      121 tattctttat ttaaaacttt gcaacagaac cttatttttc ccgtaaaggt aagttgctcc
      181 aaatgagacg acacaacttg ctagcataca aataaagaat attggccaga attcaaacgg
      241 aatagacaag aaaccaggaa ttccactgat accaacagaa gttgcaatga cgtgttgtga
      301 cgccataaat cctccaatta ttccagaggt cagaatggaa accacgaatg ggaatttata
      361 ctttagatta accccgaaca ttgctggctc agtgataccc atataagcag acaaaccggc
      421 agccagtcca acacctttca actttttatt ttggattaag aaattcattg caatagcagc
      481 agaaccttgt gccaaacttg acatgactcc aataggccaa atataatctc caccgttcgc
      541 catcaattga atatgaactg gtaaaaacgc atgatgcatc cctgtcacga ctaatggcgc
      601 aagaccaata ccataagcaa atccgccaat aaatggaact ttttggaata accatacaat
      661 acctgcgaca atcgtattac caatagcaat tgtaatcggc gctataataa taaatgttat
      721 aacactagta aaaagaattg caactggtgc aacaaccaac agttggattg tttcaggcac
      781 acgctttttc aagaatagct ctgttttagc taacacatag ccggaaacta gagctggcaa
      841 tacttgtgct tgtagtccta tcttagagat ggacaatcca aagattgtcc aatgtggaat
      901 atctcccgtg gttactgctt gcccgtaatt ccaggcattc atcaaatctg ggtgtacaaa
      961 gactagacct aacacaatcc caagaagagg atttccttta aagtatttta cagttgacca
     1021 tgttattaac gcaggcagaa attgaaagga agtgtttgcg ataagattta tcatatcagc
     1081 gacatcagca atattaggat atacttcaat gagtgactgc tcaaaaaaga ttcctgggtt
     1141 tgttaataaa ttattcagtc ccatcagtaa accagctgta acgatcgctg gtaaaatcgg
     1201 cacaaataca tcacccaata ttttaactgc acgttgaaac caattcaaat tcaactcagc
     1261 cgctactttt ttaacgtctt ctttgtttgc cccactcagc ccagattggc ttataacctc
     1321 ttcatagata tctgctactt taggaccgat aacaacttga aactgtccat tagcattgaa
     1381 ggtacccttc acatcttcca ggttttccaa tcctgcctta tcaactttag tgtcatctcg
     1441 caaggcaaac ctcagacgtg tcacacagtg agtcagtgct gcaatattct cttttccacc
     1501 aacaaagtta atgattgatt tagcttcttc tttattactc attaattctt acctctattt
     1561 cttctttatt agttaatgct tgagatgaat cattgcctac catgatccaa taagcaccat
     1621 catctataat ttcgttgaac tcttcatcat aatacttaaa atctttgttt gtaagttcaa
     1681 aagaaacagt cacactatcc cctgacttaa caaaaacctt cttgtaggct accaagtctt
     1741 ttgttggtct tatataacga ccatattgag ctccaatata tagttgaaca acctcataac
     1801 catctctact tcctttattt gaaacggtag tagtcacctt ccaacagttc ttacccttct
     1861 ctttaatgct aattggtgac atagaaaaag tggtataact caacccatac ccaaagggaa
     1921 attgtggttc attggataca tctaagtatt tggtcgtatt aaacttttca cttgaatacg
     1981 gtctaccagt attgaaataa ttataataaa tagggatttg tcctaaatgt ctcggaattg
     2041 ttattgtaag ctttccggct gggtttattt tgccacaaag gacgtccaaa atagcattgc
     2101 cagcctctgc tcctagatgc caagcctcaa ctaatccctt acatatagat ttttaaatta
     2161 cacactagtt taaactaaaa caaacaagga aaaacttacc atttaatcaa aaaattagct
     2221 catatgaata tattagaatg taaattagac tggtcaaaat ctggtcaaaa aagaggacga
     2281 atacaggtag tcctcttttt tgttattttg atattctaaa tcatttttta ttggattatt
     2341 cccttgttcg atatagaccc aaattgatct atcaataatt atcaaactga gtcatataga
     2401 gacaaaaatt tcaaaaatga cctgttaaat ggtcatcgaa tatcatttaa aatcaatacg
     2461 acggagtcag acacggagtc aaaacaagcc cgctgagagt aaaaaatata cagtcccgta
     2521 ggtaaagtgc cacaggactg tatatttttt tatttgagat tacctgaaat gattccattt
     2581 aatttttatc tcattttttc ctactagtta gtatcaaata ctctcctatt ttctcaataa
     2641 actattttgg gttacatggt atctgaaaca gctaaaacct tgtcattata gcaaaaaatc
     2701 actttatctc cgtttcattt cagatacatt tcacttaagc ggattccaaa aaaacaaaag
     2761 aaaaaggaac ccctagttag cctatgcttt ttattggttc ctctcaaaac acggtcatat
     2821 aacaacgggg tggggtaaat gaatgaaaaa ggtggaggaa acattattca atagctgtct
     2881 taaatacttc gttataaaat gtgaacaaat aaaagacatc tatccctatt ttctacactt
     2941 ccacttgact accatctttg aatcgtacaa ttttcttaac tcttctcgtt tacctcaatt
     3001 cattctcaag tggaatcaac tcatcatcta acattttacg ccatgctcgc ttcatttctt
     3061 gtgggtattt aaatggcttc gcttctggat gtttggcttt atatccttcg taatccttac
     3121 tgttgataat tgctttcata ttaggaattg gatcttcacc tggtagatat tgcagattag
     3181 aagcatgtaa ttctttctca gaaacaaacc actcattgga aaagacatga atcaaatcat
     3241 cactcgcttg tgtaaaatag cgacgtttaa tgacaaagat atcttcatta ctatctaaag
     3301 tccccacatc aaatgcattt aaaatttgtc ggtaaacttc tttgactcct tctgttttat
     3361 tcaatttagc caaagctttt tcaatttctt ctcgtgcatc tgaactattc gcagcataag
     3421 ttcctagtaa ttgatcaata taagttgaat caatatcata caacttagtg gtattttcac
     3481 tataaaattc gatcgttgaa aaatcttctc cttctttttc tggttcttcc tctattaatg
     3541 aacccttcac ggtctcgtac acgccaattt gttcttccaa aagttgaatt tgattgttca
     3601 aagttggaga tttcaccatg tcatcattgt aatcgtcata agtcactaac gattcataag
     3661 cacgattcaa ttcttgaaat gctttgacgt actcgatacg gatttcaagt ggcgtatgtt
     3721 catcaatgga ttccatggat gaaacctctt ttaacttacc atatgcttgt ttgaatcttt
     3781 ttttggattc ctgataactt ggataaatca aacctgattc ttcttttgct tttgaataca
     3841 gttttgtcgc atcctcgaca ttcttctcca ttgtcgctgg cttacgaaac gtcacaatca
     3901 atccttttgt cttatcagga tacgtacgat tcgtacgtga aaaagcttgg atcaatcctg
     3961 catactctag attacgatcc acaaataggg tttgaatcgt aggggcatca aaacctgtta
     4021 atagacgatc cactacaatc gctaaatcga tttgtttccc aaattgtttg aattccgctc
     4081 tttttcgtgc caaacgatta ttgatgtctc cgttataacg ctcaatgtct gctaatgacc
     4141 aggaagtatc ataatactga ttatattcct caataatttt ttgcatttct tcttgttggg
     4201 cacttgaatc tcggctattt tcttctaatg aataggtaat agcgattcgt ggaaaatcag
     4261 gatcctccat cgttcgtcct tcacgaatga gctgattggg aaactctttt gttaaccaat
     4321 caggctcttt cgtcatctct ttgatggccc gataatactt tttggccatg tcaatggaac
     4381 tcgtggttaa gattgcagat ttcgttggcc tgccatttcg aaaatcaaat tttgtatagg
     4441 cattatctgg acggaacatt ttatgaatga ctttttggat atgttcatct gcttcaaaaa
     4501 cagctgggtc caaataactt tcttttttga caggttccat ttgatcaatc atacgattga
     4561 tctgttctga tgaatactct gcatatgttt ctacttcttt taatttccga tagattttat
     4621 tctctagtga agtcggctcc acggtgtttt catgctctac ttgaaatcct aagacagagc
     4681 catcttctag cgcattctta atggtatagg tatgcaagac ctctccatac tgatcatggg
     4741 ttgtacgtgc caattgccct ttggcttgtt tccgattctc aggaaaaatc ggtgtacctg
     4801 taaagccaaa ccaagtggat ttcggaaaca tttttttgat ttcttccata ttttcagcac
     4861 ttaacgctcg atgacactca tctactacaa acacgatatg ttggcccatt aatttttgga
     4921 agcgattggt tccttttttc tcttcttgtt tctttgcata tttcaacgcc gcatctagtt
     4981 tttgacgggt tgtaatgatt acaacatttg cattggcatc tgccaacagg gtttcactta
     5041 attctttggc acttcccgtt ccaacgatca agctattcgc tttggcgttc ccggaagaaa
     5101 tcccagtatt aaattccgaa gcaaattttg taaactctgt ggtggtttga ttatctaaat
     5161 ctttgcggtc cactaacatg atcgttcgat cgatccccga ttttcgtgct aaaagcttag
     5221 tagatacaaa actagtcaac gtctttcctg aaccagtcgc atgccacaca taccctgatt
     5281 gatgtttatt tgcggcaata aacaaggctt gaatcgcatg tacttgataa ggatgtaaca
     5341 ccatgagggt tttattgtct tgatcttcac tgacgattgt ataatccgca atcaaacgat
     5401 gagcatccgg gatatttaac acttgtttac aaaactcata taagttttct actttttcat
     5461 tgtctttcgt tcgccaacta aataaaaact tagggtgcaa gtctttcggt aaggcatttg
     5521 caaaataccg agtggtttgt tcattggaaa ccacaaacaa ctgtaaggtc gaaaagatat
     5581 tgttccgaaa cataccttct tctgcatatt ttttgatttg gttaaatgcc tgataaacac
     5641 catcttttgc agttacttgt ttcagctcga tttggacaat cggtaatcca ttgattaata
     5701 aggtgacgtc aaaacgtcga tcccgtgctt ctatgttact tccacgtttt gcaatttgat
     5761 ggaccacttc ataagtagag attcctccac caatgtcttg attggaataa aggataagtg
     5821 agacagaacc caattgcgaa tcttcccgtt caatcgtgat ccgagccatc ccattttcac
     5881 cttttaacca tttcgcagca tcaaatgggg ttttcgttcg cagcagtaat tccgttttga
     5941 tcgtttcaaa ttctttatcg gtcaaaggaa aatcattcag ttctgcttga ttatttgaga
     6001 taattttttg gcgtaaattg acccaaaggt cttcttctga ttttagatcc ggacgatacg
     6061 tccactgatt atgcccttct ccaagtacac gaatcaactg ttcttcgact tctgcttcct
     6121 cacggtgact aattttcatt cttcttccct cctagacaaa catcttttgt aagaagcttt
     6181 ttttcgtttc ttttagtaaa tctaacttac gttgatgaag agcgatcgta tcatctagct
     6241 gtttgaagaa agtaccgatt ttttgttgtt catcctttac aggaacctta acactgatat
     6301 tctcaatatc agaactgtta taagaaggca atgcccctac ttgggagtat cttggcaaat
     6361 ttatagtttc aaacaatatt ttaccaaaat agatatccca agtattatta aataaataag
     6421 ccatggtatt gttatctatt aagaaagggc ttgtgaccaa acgttttcta ttaagcatta
     6481 ttgctgcgcc aactttagca aatataatcg ctggcacatc ttttattggc ttccattttt
     6541 tacgctcaat ttgctcatta gatacataat gatttgcatt tctcatttca tactcattac
     6601 caatgttatt catgtcggaa actttaaaaa atggagtacc ttcagaacca ccttgctcgg
     6661 catcaggaaa tccaattccc gattgagttt tacctaattc tcccaactta cgctcttccc
     6721 aatcttccgt aaaaccagga aaccggattt ctggcacttt tgctccgttt tcagggaaca
     6781 ttttttgtaa gaatcctttt ttcgtttcct tcagcaaatc taacttacgc tgatgaagag
     6841 cgatcgtgtc gtcaagttgt ttgaagaagg tgccgatttt ttgttgttct tcctcactag
     6901 gaaacattgc tactatattt ttaaactttt ttagagacag aacatgttga cctgttccct
     6961 ctgcttgaat agataattgt cgttggattc cattgttaat acgtcttaag aagaagtcgg
     7021 aatcagcaga ttttaaagta aatacaggat aaaaatagct tataatccct ctatcaataa
     7081 tgtcattacg gttaaacaca aacacatcat tatcacttcg actacggaac gtgaaatatc
     7141 ctctaggtag tacaaagtaa ccaatattat tttctgtagt tacttgccga tttgcaaaat
     7201 agtcttcttg caaaactatc cctttttgtt gagatgaagt tagcatagga aattgatttt
     7261 gtacacttgt cttttcaaca taatctacaa cgaagtcccc caacttcctc tgttcccaat
     7321 catctgtaaa tcctgggaaa cggatttctg gttgtgtatc attgctcatg tttgaacacc
     7381 tccagcgcac cttgtaacca cgcttcattt tcaggtgttg tttgcaggga agagatagct
     7441 tctaaaagtt ttttttctag cacttgctgt tcttgtcgta tcttcttgat gtcatttccg
     7501 acatgaacca tatcaattgg ttcttcttct tcgaaagtat ctacatagcg tgggatattt
     7561 aagttatagt cattttcttt gatttcatca aaggttgcca aatgagcgta tttctcgaca
     7621 tcttttcttt cagcgtaggt ttcgaggatt ttttgaatgt tttcttccga tagtttattt
     7681 tgatttttcc ctttaacaaa ttcacgacta gcatcaatga ataatacatc tcgagtttga
     7741 cgattcttct tcaacacaat caccgtcgtt ggaatcgatg tcccaaagaa caagttcgca
     7801 ggcataccga tcacagcata aatactgcca tcttctagta atttttgacg gatgacccct
     7861 tctgcagcgc cacggaataa aactccgtgt ggtaagacga tggccatggt acctgtttcc
     7921 ttcaaatgat agaacccatg aagaagaaac gcaaaatctg ctttggattt tggcgctaat
     7981 ttcccataac gattaaaccg agaatcatct aagaaagtcg tatctgctga ccaattagcc
     8041 gaataaggtg ggttcattac tactgcatca aatgtgtaag gttcatctgt tggccagtcc
     8101 ttattcaacg tatccccatt gcggagattc atttcttcgg cgtcgacacc atgtaaaatc
     8161 aagttcattt ttgctagatt gtatgtcgtt gtatttagtt cttgcccatg atatttaacg
     8221 ttatctgggt gtgttaagta gttacgtacg tttaacatca atgaacctga acccatcgtt
     8281 ggatcaaaaa cactaaagaa tcgtcgttcc ttttgatcga gcgttacgat ttgcgccatc
     8341 atatcagaaa ccatatgagg tgtgtaaaat tctccggctt tcttccctgc ttctgaagca
     8401 aattgactga tcagaaactc atacgcatcc ccgatcacgt ccccatcgtg ttctaaaaca
     8461 tctacatcat tcaatttctt gatgacttcg gtaatcgtca catttcgttg ttgctcatct
     8521 gttcctagtt tttttgattg gagatccaca tcatcaaata acccattaaa ttgattgtag
     8581 gtagatgcca attgcacaaa ggctttgttt agatcgttca attggaacgt tgcttgtttt
     8641 gcttgatccg ctaagacgtt gaaaagatac tctggtgcaa ttgcatatcc caaaatatca
     8701 acgattgtgg caatcagatc ttcttttgat tcttcatctg aaagtaattc acgatacaac
     8761 attgtttgtt tgcttactgt gtcatattcc tctaaggatt catctgctaa aagaaccact
     8821 tgttccaaca atcgatcgga taaatattta tagaaaatca gtcccaataa ataattttta
     8881 tattctgacg catccatttt actacggaga ttatctgccg cactaaataa tttttgattt
     8941 aattctgcac ccaaaaagat acactcctat ctcttattta aagttgctat ataccctctt
     9001 attttagcat accccctttt ataaaaagca aaaaaaaaaa gaaagaaact tattcttgct
     9061 aataaactac gcgaaaggag tctaacgttg tttgatataa cttagactga tcgttaactt
     9121 attttttata tttctacata gttatcttta gaaccatttc agatacatat gaaacaatta
     9181 catatgattt tttcataaaa aaacagtact gtctagtagt ataaaatata caaatttctt
     9241 aaaaattttt tcactaaaat cactacctga aacagtctaa aacacttata tatcaacgtt
     9301 taatgaaact atctccgttt catttcagat acaaataaat atagtcgggc tccaaatccg
     9361 aaaaaaaata cccccagtag cttatcctaa gctactggag atgtataagt acggtcatat
     9421 aacaacgggg tagggtaaat aaatgaaaaa gatggaagaa tcattattca ataacttttt
     9481 taaatacttc gttgtaatca gttacctgtc cgttcttaaa taccacagaa taatcttttt
     9541 tcccattttc aagtaaccga agtggaatgt ctttaccaac ttgctctgtc actgcattac
     9601 tgatacctgt tagattagct aataaatctg ataaagattg agcatctgta gaaatctctg
     9661 tatcagtatt tatcgtgatt cctttatctt catttacaag cttccaagta ggtggtatag
     9721 ctgtgtatgt ttcgatgaat gaatcaattc tttcatctat cgtcttccca gtatctactt
     9781 ctgtctcatt actcttagat gaatcgattc tttcatccat cgtctgctcc gtaactgctt
     9841 ctgtctcatt attctcaccg gaaactctct tcacacccaa acttatatat tgtccatctt
     9901 tagtgtgcat agttaaaatt cccacgcttt tactaataaa ttcactataa ccagttcttt
     9961 caatagagac ttcaatgtat ttcacactat catactcaaa agaaaaatag acatgtaaaa
    10021 gcattttgtt gtttacatct acataataat cctttgactc tacttgagac cttcctatac
    10081 ggaatacagc tttactgtct gatatctcta taccagcatc cttattatta atctgccaat
    10141 ctccaagtag ctcttctggc aagctagtag tttcttgtga acactttacc acttcactgg
    10201 tagaggtcga aacattcacc tccgcactgt tagaagaatt ttccaaggaa tcaggagcct
    10261 tagcacaacc aacaagtctt tatatattgt gcagccgata ttttcttcat tcagtacacc
    10321 cttgaaatat gcagtgttag ataaagcagt tcgtcctgat ttgctgaggc acccatctct
    10381 tcttgaacgt actccttgat tttcaaggcc gcccgatact ctttcggaaa acgctgcttc
    10441 actgaagcca gcaaaaaatc atccttctcc ggcaactctt ccttcttaat cattcgggca
    10501 ataaaaaact gtaaatgcgt cacaaatctt aagtaaagca tcgaatcttt atcaaccttt
    10561 ttttcgggaa acagatatcc tagcatagcc aagatatcct ttagtgctct taccgagagc
    10621 atggtttctt ccatatttgc ttgttcactt tgggcattta caatgtgaaa cgcaatgttt
    10681 ccagcctcct cttctggcaa ctgaacattc atttttttgt tgatcaattg gatagcatag
    10741 cagccgatct caaattcttt tgggtaatac ttttgaattt caatcagcag gcgattttga
    10801 aaaacaatgc ctttttgact gcgttcaatg gcatgcttca agtgatcaac caaggtaaaa
    10861 aatagacttt tattcagctt aaagtcaaac ttggcgttgg cataatcgat aattcgcttg
    10921 acgcaaataa ttagatcatc cggagcagcc tcaaacagtt taatgtaatc cttttttaga
    10981 gcatcagaaa gtgaatctaa tttaaatact ttttggattt tgtcagccgg aaccaaatcg
    11041 cctttcttta gttgaaatcc aatccctttc cccatcaaaa ttacttcttt gccttgctta
    11101 tctaagcaaa gaattaaact gttgtttaac gttttaatta ctctcattag attcaccgtt
    11161 ctctctaagc taagccattt cttgcgatta ctttttgata ccaaaagaag ctttcttttt
    11221 ttattcgttt taattcttta agattctcat cggttcggtc aacatatata aaaccataac
    11281 gcttattgaa gccttgatgg gtactaacaa catcaatcgc tgaccaaggt aaataaccaa
    11341 aaacatctac accatctgtt aaagctgctt gaatagccag aatatgtttg gctagataat
    11401 caattcgatc ctggtcatta attcgtctat cttcctcaac tatgtcgggt gccccatagc
    11461 cattttcagt aattaaaata ggtaaatcat agcgatcgta caatttcctc aatgttaatc
    11521 gtagtccagt agggtcaact acccagccat atggcgtttt atctacataa ggattttcag
    11581 ctgcccggta gacaccttct tctcccaaca tgatctgttg atcccccgct ctagcggaaa
    11641 catctgatcc gtcatttttg ctggcagcga tggtggcagt tgaataataa ttaatcgcaa
    11701 taaaatcggg tttaccggag gataaaattg cctgatcctc tgcctcaatt ttaggatata
    11761 atccacgatc attcaaatag ttttcaaaca aataattgta ttttccccga actgctacat
    11821 ctaagaaaga ccagcctctc aatgtttccc aattatgggc tgcaattgca tcttctggac
    11881 tggaggtagc ttgatacata gccgttaaat tgattgctgg accgattttt cctttaagat
    11941 tcaactgatg atacaagtga attactctag cttgagctaa taaaacatgg tgattaattt
    12001 gaaagagttc tttttttgaa ggcagctctc cacttggtgg caaaccaatc gctccaggat
    12061 gaaggatcat cgtgttttgc tcattaattg tcagccaata gttcaccttg tcaccatact
    12121 cagtaagcaa tacctgtaca tagtccacaa aataatcgat agttgctcga tttaaccaac
    12181 cgccctgctc ctctagaaaa taaggtaaat cgaaatggta catggtgaca atcggttcga
    12241 ttccctgatt caggcattca tcaattactt gatgataaaa agaaattccc ttttgattgg
    12301 ttttattatt ttcaatatcc ataattcgcg tccaagcgat ggaaaagcga aaagctttta
    12361 agcctaattc tttaaacagc tgtatatctt ctttatagtg atggtaaaaa tccgaggcaa
    12421 cttcaaaatt agctacccct tctgtatgct gatacttgtc aataatagac ggttgtttcc
    12481 catcctcctg ataggcaccc tctgcctggt aggcactaat ggaggcaccc cataaaaact
    12541 tctctggaaa tgctgaaagc tgtttgtatt gcacaaaaat cctctcctta actaatttgc
    12601 atcaatggtt cgtgttcctt taagcttccg cttgcttcac taattcctgc gtaattttca
    12661 ctgttggtca ctaccacaat cactgtatca tcgtagccag cgtttctaat ggcagcgaaa
    12721 tcggcgttga ttaataattg tcctgctgac acctgatctc ctgcttttac aaatacttca
    12781 aagggttccc cttttaaatt cacggtgtcg atccccacat ggatcaataa ttcaatacct
    12841 tctttagaac gtagaccaat cgcatgttta gattctaaaa tagtaatgac ttctccctca
    12901 acaggtgaat aaatgctgtt ttcttctgga tgaatggcta cgccctttcc caatagtccc
    12961 ttagaaaaga cagcatcgtt cacttcagaa ataggacaca cggttccttt taccggattt
    13021 tcaacaatga ctgcttcggc tattgccgtt tgctctgatt catcagaagt atcgtcaaat
    13081 ccaattagat aagcaatgat aaaggttgca acaaaggcga ttacacacgt aataattgcg
    13141 tgaacaatat tcattggatt ttctccaata aaggctggta aggctgctaa gccaggggaa
    13201 acaaaggcat atctgactaa accgctcaag ccagcataca aaccagcaat tgcaccacca
    13261 atcatggaag caactaatgg ttttttcagc ttcaaggtta ctccatagag tgaaggctca
    13321 gtaattccca ttaaagcagt gatcccagtg gacacagcta gctgcttcaa ctctttgttt
    13381 ttagttttcg cggctacagc aaaggtagca cctgattgag caatattaga agccagcatt
    13441 cctggcccat tgatcatttc agaacccgta ctgctcaatt gcatagtagc gattggcgtc
    13501 attgcccaag ctgtacccgt aaccaccaaa aatggctgca aaccacccat caaaaatgga
    13561 attaaccaag ctgctttgcc gttaatccat tcagccccca ttgctataag atcgttcagc
    13621 aacgttccaa acggtccaat gacaaccaac gctaaaggcc ccataattaa aaataccagc
    13681 atcggcttag taaagaattt aataaacgaa ggcgaaattc gatccgcaaa gggctctaca
    13741 taggacatga tccaaacagt aaagataatc ggtaaaactg atcccgcata atctgcagct
    13801 aataccggaa ttcctagaaa agaaacggca tcgccagtag aaaaaagctg tgaaatattt
    13861 ggatgaagca aaatgccagc aacagtaatc gccaaaattg ggttgacatc aaactttatg
    13921 gctgccccat aggctaatag tactggcata aaataaaagg ctgcatcagc aatagtattc
    13981 aaaatgatgt aagtttgact actgtctgat agtacaccag tcaaagtcaa gacggccaaa
    14041 atggctttta ccatcccggc acctgttata gctggaatca tcggtgtaaa ggtggtagaa
    14101 atgacactaa tcaatcttga aataatactt tcttgattgt ctgaagaggg gcccttttta
    14161 attgaagttc ccacttcctt ttgaatttcc ttgaaggctg tttggacttc attgccaatc
    14221 accacttggt attgtccacc gctatccacc acactaatta caccaagtgt tttttctaag
    14281 gctttcgtat cggctttcct tttatctttg agttcaaaac gcagtctggt ggcacaatgg
    14341 gttaagctga ccacattttc ttttccccca acctgttgca atacatttct tcctacttct
    14401 ctgtaatcca ttattctctc tccttaaagc agtaaaaaag accaagtcaa accacgcccc
    14461 aatcaacatt gaagtgttag tttgtcttgg tcttgcctgc ataatcagta acatgccaat
    14521 aacgttattt tgctgtaatc caataatagc acattatgat agcgcaatca acagggaatt
    14581 taatttttta tcttttcgtt tgaccgtata gggtaatata acagttagat cacatcaact
    14641 agggtatatc tgcgtatact tgctgctaaa ataagtatat ctaatattaa ctataccagt
    14701 aaaaccattc ctacataacc agcgggaaat tcccaaaatc gtgaaagcat caaaaatgca
    14761 tataacggat cacacaactt caacaattct gctcttggga aaaattgatg aatttggtga
    14821 gtaaaggatg gaataaacag cattccaaca atataggcaa caatagtgat acttgttttt
    14881 ttggtaaaaa tcagtaagca atagccaatt tcaatcattc cgagatataa aggtatcgat
    14941 agaatgattt gggctagtat tcttaaaaat taactagcaa atgtttaaac tgatttattt
    15001 ctaatctaca tgtagtaagt atttcaattc caccaattat caataaaaat accaaacata
    15061 tccataataa ttttttcttt ttcatttctt ttatattgtt ataacagtga ataacataaa
    15121 aattcccgac aatcattgta atattttttt gtcacctgta ttagtattta atttatagga
    15181 aactataaaa actccctagt gaatttacac ctttgggagt tcctgtttgg acggtatgca
    15241 taatacattt aaatcaattt aacattaaca cctcagcata tggtatctcc acatatatac
    15301 ggtctttctt tggatagtac tcaatattta tgttgatagc acttccattg tctaatatag
    15361 ctttagcccg gtatgtgtta tctccatttt catgagtaat cgtcacatca tcacatgatc
    15421 gatttaagtt gtactgttct tgtaaaatct gtgttaccaa tggttttgat gacttctcta
    15481 atccagatgt acctgtcatt tttgaaaaaa taatacctat aatagccaag acaacaatac
    15541 ctataatgac aaacttcttg ttcatattta ctttattcaa ctttttatct cctatctcca
    15601 aaataatttg ctcttatccc tcttatcagt acattgacat ctctaaaagt acaccaaaga
    15661 ttgctccagc tacccctgct atcatcaaaa tcgtacccat tttctcatct ttttctcgat
    15721 ataagtagcc cataataaca gcaacagcac caaatacaac aggaataaat gctaacgata
    15781 ctaccataga aatccaacca ataatcaaat acagcttccc tgtctcttgt ccatgtacga
    15841 tttgttcctt catttcatta attgtctgct cagtactttt ctttactgtg tctgttccgg
    15901 ttgtctcatc tgtttcttgt agtgccccac aaaactggca atacttactt tcatctgtta
    15961 tttctttgcc acattttcta caatacatgt cttctcctcc taaaatcatt caattgctta
    16021 ttagttaact gtttacttta ttaaatacat cagaaaacag ctcattcatt ggtacactta
    16081 atatctcaga aagcatcttc atttgatagg gtttaggaat cgttctccct gtttgccacg
    16141 aacttacaca ttgctgtgta acattcattt tttttgctaa ctccgtttga gaaagtcctt
    16201 tttcttttct gtatcggctg agattactta cttttttcat gattctcccc tcctgtttta
    16261 ttatatacaa caatatgatg tatttcaact cataaaatat aaaaaacttt aaataccatt
    16321 acaaatacaa caacttgttg tactatactg agatgggggt gtattaatga aacagaaaca
    16381 atatgcaaag gtcattagag aaaagcgaaa agctctcggg tggacacaaa aagaattagc
    16441 tgaaaaaatc ttctctacac aacaggcagt agcaagatgg gaaaattctg taacagagcc
    16501 taacctcgat agcttaacag ctctttctag agccctagga acccctgtaa gccattttct
    16561 agacaatgtt gtcgtagatt atgaggaaga gtttttggct ctctatcgtt ctcttagcac
    16621 tgaagatgca gttcgaacaa ttgactatat gaagctatta aaaaggcaag aaaatgaacg
    16681 caatcagcta ttgaaagatt gaaaaataaa taacccaccg aactttaacg gtgggtgtat
    16741 tgagatgaaa taagattaag agctatggat aacctgtcta gtttaataca attgggtctt
    16801 ttctcttcct tactctccgt ccatcatctc ttgttacact tgtaaattga tacagaggaa
    16861 ctatcccagc tcctgataat atcaattctt ttattgtttc atctatccct gcccctttcg
    16921 ctaaatatat taaaaaacta ctacttgctt tcacattgta tagtttctta atatccttag
    16981 aagctcgttc aagagtgaat ccttgtttaa caaagtagcc tctgtttttt attaaagcat
    17041 ttttcacgct gttatcccca acattacgta ggcgttcaca aacagtgtta ataagttctt
    17101 tctctgtcat tagatatgtc ccttgccacg ataagccctg taaaacttca tgtgcttcat
    17161 ctaaaatcaa ttgtttttcc ttgctgagtt ctgatcggga attttgagga aatactcttt
    17221 tagcctcttt ttcgttaaaa catatcttaa cccattcata agaaaaatat tgatatgtaa
    17281 aatgaatttt ttccagaagt ggaaggatat cttcattcaa tttttgaatc acagaagttg
    17341 cattaaaaac gtctaatcga tagacattgc ttctcttatg attaaagttt cctaacgctt
    17401 tctcttcctt taacctattt aggtattcga gcatcttcaa aggaacatct tcatcatcta
    17461 atttttttat caatcctata aaagtcataa gtgatagtaa cttattacat ttatctatgt
    17521 cataagtttt accatagtaa gaactcattt ttttagctaa ttgttccccc gacaaaatac
    17581 aagtcacact ttccttacta tcatcaaaaa aattaacatc agaaagcaag acatcataga
    17641 cacgtcgcat ttcctctaga taattcctta ttgtcctgaa aagtttgtct ttcattgatt
    17701 caagagtgtc aaaaagtact tttgattcct ctttcaattt tcgaaaatgt gtaggataca
    17761 agtctaggtt ctctaatagc caattaaatg tttctacccg actgtctttc tttaaaatta
    17821 gcatcacaac tccaataaaa ttttcactga tatcacaatt actggaatga caataaaaaa
    17881 tggaatgccc agttttactg gtaaaaatac tagcagaggg attatgatcg ttgtgaaaca
    17941 gacatcttaa gtttttactt gacttaagta atttattcat atcaatggtt aacaatcttt
    18001 cataaatctc attaaaagac atgtcggagg aatcaaacag gcagtcttta aaccactgtt
    18061 tcatttcttc tttgtcgtca ttttttatca acttaacaaa atcggtttca ttgactagtt
    18121 catactctct ccctgaatca ctttgacaat ttttagaaca tgtcatggta aaatcaatcg
    18181 gaagctcagt aatatctaac atgttgtctt cattaattat tatcactgca tctgacttat
    18241 atcctccaaa aaacattcta ttcgaagcat ttacattgtc atcacacccg gggatgttct
    18301 ttttcaagta ttcgtaaaca gcaaccattt taccatagtc agtaattgct tcttttaata
    18361 gaaagacaat cttgtatttt tctagatttt cagagtaccg aatacttttt tgtatcgcaa
    18421 acgcagaatt atgaactaaa ttgatagata aaaccttttc tatgcttaag tatctactat
    18481 catctttact caaatctact accttcccct tctcatcttt aacagtgtta tcgacatcca
    18541 gaataattac tctggtttcc acaaaactct ccttgtcatt gcctttattc tttgtcttgc
    18601 ttggaataaa tgattgtgat gaatttagta tctctacaaa ctcatctctt gtaacttctc
    18661 tatagttatc taaacaccta tctcttacat cagttttttc tttttttgta actggcttct
    18721 ctaataattt ttcttgatct acataaattg gaatattaat cattgatgtt tccatttgtg
    18781 tttcctcctt ataaaattct gttaaagact aaaacataca gataataaaa acaaactctt
    18841 tattactata tgttttagtc ttatttgttt actcaacctt tataccgttc catgaaacta
    18901 tcaatatcag attttttaaa tctaatgacc gtatcaattt ttataacagg taacccgtat
    18961 tgagaaacat attttctaat cgttcctact gatacaccta gatattcact tgcctgctga
    19021 tagtccatat actctagagt gactccagaa ataatgtctt ctagcatagg ctttagcact
    19081 gtaattatct ctttcacttg ttgttcaact tgtatagaaa caatgctatc aatgatttgt
    19141 agagacatat ttccccctcc tttcgtgatt gcttgaacaa attttctaag aattatcttc
    19201 gtattttttg ctcaaaataa aagtattttg ttattaaccg attaatcaaa caaaaaatga
    19261 ttaccagttc atcgacatac acataatacc tcgataaaaa aggggtgtca acagctttgt
    19321 aaaatttatt tacaacaccc ctttttttga ggtatactaa ttttaggagg tgtggtcaat
    19381 atgataaaac gtccaccaat aaattattta gaacgaaaaa agatactcgg aacaaaaata
    19441 aaagctataa gaaagagtaa aaaattaaca caaccagcat ttggtcttat gattaacaac
    19501 ggtcaattaa ttgacaaaaa aactatctac gaatgggaga agggaaccta tttaccaata
    19561 ccagagcgat tatcccgaat tgctgatttg ggaaatatga gtatagagga gttagtttgt
    19621 ggcaatgtag aagaatatat tttgggaatt attctttata gagatagcat tgtactagat
    19681 ggtataacat ttccagataa aaacctgttc cagcatcttc gtcaacagtt cccaccagta
    19741 cactctaatt tagatacatg gctggataga tattccaaat tagaaccaga gatgcaagaa
    19801 tttattgcta acaagacttg taataaagtt aaaaatgaaa aaattagtct tttcaatatc
    19861 ttaaaaatag aagaattatt catcaatgtt attgtagaag aatttgacaa taacattctt
    19921 ttcctcacta gcagtataga agaactacta gaaagaatgg tagatgaatg gctacctatt
    19981 caattgaaag acatgtctta tcccgaagaa gctgtgagag aaattactga taatataaac
    20041 aagctagaac aaacgatttc atcaattggg aaaaaataca ctaagaaaaa aatgaaggga
    20101 ggtgatacca tctagtggta agtactcctt gtaaactaag aggagatgat ttaatggcaa
    20161 aaatatcaaa gtacaaaaag aaaaacggtc aagtggcgtg gatgtataaa ggacacattg
    20221 ccaccgatcc acgaactggt gaaaaaataa atactacgag aagaggtttt agtagcaaac
    20281 aagaagctca aaaagattat gacgagtaca gacatcaaat attatacggt gttaaaaaga
    20341 aagcacctga tatgacattt gaagacctgt ataatgaatg gataactcat cagcgtacca
    20401 gtgttaaagc ttcaacaatc gcaatctcag taagatacgc aaataatcaa atacttccag
    20461 catttggtaa gcttaaacta tcgaatatct ctgtcccata ttgtcaaaaa gtggtagatg
    20521 aatggcacag taaatatgaa agttacgatt atatgagaaa acagactgca caaattttac
    20581 gctacggggt tgcaatgcaa tatattgaca ataatcctat ggaaaaaaca cttcttccac
    20641 gaaaaaaaga gtatgagaaa aatcgtaaat tttactcaaa agaggagctt aataatttac
    20701 tggatgcttt taaagatttt ggtaacatga aacaatacgc cttcttcaga ttattggcat
    20761 acacaggtat gagaaagagt gaagtactcg ctttacagtg gaaagacata gacacgttta
    20821 ataaagaact acatgtcaat aaaactcttg ctgtagatga atttggtaaa gttataattc
    20881 aatctccgaa aacaagagct tctagacgag ttatctcttt agatactgag actctttcta
    20941 tcctcaacaa ctggaaatta cagcaaaaag aagagtattt aaaacttgga tacaatacta
    21001 gctctaaaga gcaacatgtt tttacaacag ttaaaaacac tctatacatt ccaaacactg
    21061 ttaatgattg gttaagatat attttgaaaa aatataactt gcctcgtatt acacctcatg
    21121 ggtttagaca tacacatgct agtttattat tagaagcagg agaatctgtc aaggtagttc
    21181 aacaacgatt agggcatgaa aatagtaaag tgacattaga catctatgca catattacaa
    21241 ataatgcacc taagaaaaca ggtcaagact ttgctgatat gatggctcat cagtaaaaga
    21301 gctggtcaaa atctggtcat ttctagtata caggcaaaac aaaaaagcta gaacccttat
    21361 atatcaaggg ttctagctcc tataacaggt ttacccaaca ctgccttcca tctcataact
    21421 gatcaatcgg ttgagttcga ctgcatattc cattggaagt tctttggtga atggttcaac
    21481 aaagcccatg acgatcattt cagtggcttc agattcggtc aggcctcggc tcatcaggta
    21541 gtagagttgt tcttctgaga tttttgagac tttggcttcg tgctctaaag agacttggct
    21601 gttgtggatc tcattgaatg ggatcgtatc ggatttcgac cattcgtcca tgatgatcgt
    21661 gtcacattcg atatgagaaa tcgaactcgc actgtttttg gcaaaggtta cttgtcctcg
    21721 atagtttact tcgccgccgt cttttgaaat tgatttagag acgatagaac tagaagtgtt
    21781 tggtgcgttg tggatcattt ttgcacccgt atcttggatt tggtttgctc ctgcaaaggc
    21841 gatggagagc atggtgcctc gtgcaccttt tccatctaag taaacacttg ggtatttcat
    21901 cgttgttttt gcacctaggt ttccgtcaat ccattcaacg gttgcgcctt cgtaagcttt
    21961 tgctcgtttg gttactaagt tgtacacatt gtctgaccag ttttggatcg tggtgtaacg
    22021 gcaatacgca tcttttcttg taaagatttc tacgatggcg gcatgcaaac tattacttga
    22081 ataagtaggt gccgtacagc cttcgacata gtggatgctt gctccttcgt caacgatgat
    22141 cagcgtacgt tcgaattgcc ccgtgttttc cgcattgatc cggaagtacg tttgtaatgg
    22201 gacatcgact ttgacgcctt ttggcacgta aataaaggtc ccgcctgacc atacggctga
    22261 attcagcgcc gctaatttgt tgtcggttgg cggtacaagt tttgaaaagt actctttgaa
    22321 taattcaggg tattctttca aagcagagtc agtgtcagta aagacgatcc ctaatttttc
    22381 gaattcatct ttcatattat ggtacacgac ttctgattca tattgtgcgg aagcaccggc
    22441 tagataagct cgttctgctt ctgggatacc gatcttctca aatgtatctt tgattttttc
    22501 tggtacgtct tcccagtcac gagcgggttt gtcacttggt ttttggtaat atttgatggc
    22561 atcgaaatcg atgtctgaaa ggtcgggtcc ccatgtttgc attggcattt tattgaatgt
    22621 ttctagagat ttcagacgga attcaagcat ccattctggt tcgcctttga ttcttgacat
    22681 ctcacggatc acttcttctg tcaagccttc tcctgtactg aaaaccggtt cgacatcatc
    22741 gtgaaacccg aatttatatt cttctaattc tggtacgccc atgttctcac tcctcttcct
    22801 tgtggtaatg atggaaagct gcggtaccat cgtttttcat tgcttttcct agtgctttcc
    22861 aggcaagtgt cgcacatttg atccgagcgg gaaatttagc tacaccacca agcatagcag
    22921 catcgcctaa ttggtcggga tcttggactt cttttccttg gacaagctgt agaaagtcta
    22981 cagttaaatg ttctgcttct tctattgatt ttccaatgac ggcatctgtc atcatcgagg
    23041 cacttgccgt actgatggag cagccgctgc cgtcaaaggc gatatttttg atgattccgt
    23101 cttttacatc gacttgcaat tcgatcacat ctccacatgt ggggttgttc aattcgatct
    23161 tgcttgtcga gtcggtcaag cttccacgat gatgcggatg ggaagaatga tccaagatca
    23221 cttgacggta taaattgtct aatttagata gtcccatgtt ggaaaaactc ctttgttgcc
    23281 atgattgctt caactaaacg gtcggcgtcg tgcgtcgtgt tgtagaaata aaagctggcg
    23341 cgagcagtcg ctgatacttc aaggtacttc aatagcggtt gtgcacaatg atgacctgct
    23401 ctaacggcta ccccttccat gtctaaagct gtcgcgacat catggggatg taacccatcc
    23461 aaattgaacg caacgactcc tgtccgaaaa ttcgggtctt gcggaccata aacagtcaat
    23521 ccatcgattg cttgtaattt tggcaacaca taagcggcta gttcttcttc atatcgatgg
    23581 atattgtcca tgccgagttc ttgcaaataa tcgattgcat ggccgaatgc gatagcgcca
    23641 gcgatatttg gtgtccctgc ttcgaatttc caaggtagtt ctttccatgt actgtcgtat
    23701 aattcgacaa aatcgatcat ttcgccacca aattcaacgg gttccatttc ttctaaccat
    23761 tttcgtttac catataagac accaatacct gttggtccgc acattttgtg tccactgaaa
    23821 gcaaagaaat cacagtctag tgcttgaaca tcaatggtca tgtgcggggc agactgtgca
    23881 ccatctacta cgatgacccc gccgttttca tggacaagtt cagctaattc ttgaacagga
    23941 ttgatgacac ctaagacatt ggatacatga gcaatggaaa cgattttggt tttgttcgtg
    24001 atctttttcg ctgcatcctc catatccagg aagccttctt ctgttagatc gatatatttc
    24061 aggacggcac ctgttcgttt tgccaactgc tgccatggga taacattaga atgatgttcc
    24121 atgtaagaga gcactatctc gtctcctgct ttgatatagc ggtcgccgaa gcttctggct
    24181 acccaattca agcttgtcgt cgtaccacga gtaaatagaa cttctgctgt ttcttctgca
    24241 tggatgaatg cccgtacttt ttctcttgct tgctcatact catgggttgc gcgttctgct
    24301 aacgtatgga caccgcgatg aacattggcg ttatcgtgtt cgtaatagtg cgctaatgac
    24361 tggagcactt gttttggctt ttgggtcgtc gctgcattat ccagataaac gaaaggttca
    24421 tcattgacgt cttgaaataa aataggaaaa tcattgcgta gctttttagc atcgatcatc
    24481 cattcaactt cccttcgatt acttcgacta attctttccg aacttgttct acagggattg
    24541 ctgttaagac agaaccgagg aatcctcgaa tcactaagcg ctctgcttct tctttatgca
    24601 atcctcgact catcagatag tacatttctt ctggatcaac tcgtcctaca ctggcagcat
    24661 gtccagcagt tacttcgttt tcatcgatca aaagaatagg attcgcgtca ccacgtgctt
    24721 tgtcagaaag catcaagaca cggctttctt gttgggcatc tgcacctttt gcccctttca
    24781 ggatgtggcc aataccgtta aaggtcaatg ttcctttttc tcggatcact ccgtgttgca
    24841 aaatatgccc gattgtatga gggactttat tggttactcg tgtatcgatt ccttggattt
    24901 gtctgcccga gctgattgcc acgattttga cttctgcgtg tgcaccttct cctgctaaat
    24961 ctgagtcaaa gtcagcgatc acatgaccgt cattcatgac accaattgcc cagtcgacag
    25021 aagcatctcg taaaatgtgc ccacggcgat tcatataaga agtaatattc tctcctaatt
    25081 gatctacagc tgaatatttg atttttgaac cagctttagc gatgacttcc acgatgatgt
    25141 tacctgatga ttttgctact tgttctttgg ttgtctggaa acgttccaga taagaaaatt
    25201 cactatgttc atctgccacg atcaacacat gcttgaagaa gtgctcatca gatgcgccat
    25261 cttgaatgaa taaggactcg agtggttcat cgatcacgat atttttaggc acatacagga
    25321 aaataccgct gttcataaaa gctacatgga gtgcagtcaa ttggtcttcg tccatgttta
    25381 ctgctttttt catataatat tcttggacta gttctgggta ttcgatcatt gcagtgaata
    25441 agtcagtaaa aatgactcct ttttctgcta attccacagg cagttgttca aaaatcgtcc
    25501 atgaaccttg ttggacaagc acaggattgt ctttcattgc atcaaatgcc ggaatcgtgc
    25561 ctgtttcact gatagtttgt gtttctttca catcgaataa cgaccagcga tggaatttca
    25621 cccgatcgat atgcggcaat ggcagttcat ctgcttttgt tagtgcgtct tgacggaagg
    25681 ttctcatcca atcaggttcg cctttactta aagaaaaatc atttaccgcg ttaagataat
    25741 cgagccagtt tttttctttc attcttgctc ccccttacgc ttcttcttta tagtcgattc
    25801 ctaattcttt actgattcca gcgtagcctt ctgcttccag gcgtttagct aagtcagcat
    25861 ttcctgtcat gactactcga ccttccatca tgatgtggac gacgtcaggt gtgatatagt
    25921 tcaataatcg ttgatagtgg gtgatgatca atgcaccgaa attgtctccg cgcatttcat
    25981 ttactccttt agcaacgact ttcaaagcat cgatatccag acccgagtcg atttcgtcta
    26041 aaatcgcaaa tgttggttct aacatcaaca attgtaggat ctcattccgt ttcttttccc
    26101 cgccagaaaa accttcgttc agataacgtt cagccatttc ttctggcata ttcaataaag
    26161 ccattttttc atctaacttt ttcaaaaatg ccataacaga gatcttgtcg ttttcatcac
    26221 gtttcgcatt gattgctgca cgcatgaatt ccgcattcgt gatacctggt atctcacttg
    26281 gatattgcat agctaaaaac aagccaagtc gtgcacgttc atctacttcc aagtctaaaa
    26341 cattttttcc gttaaacaag atttcacctt ctgttacttc atagtttgga ttgcccatga
    26401 tagcggcaga taaggttgat tttcctgtgc cgttaggtcc catgatggcg tgaatttctc
    26461 cggttttcat tgttaggttt acgcctttaa ggatttcttt ttcttcgatc gacacatgta
    26521 gattttttat ttctaagaca gacatgcatt atacccccaa attctctttc gttctcactc
    26581 attttagact aattgagaat gaagcgcaat gatcttcctt actaaaatca aatatctttt
    26641 attgattatt aaacaatttt gatttctaaa ttagaatagg tataaaaaag atgaggaata
    26701 agccgttaca gacttatttc tcatcttttt tgtttcattc cttattttgc atcagccttt
    26761 actggtttaa cagagccgcc ccatttgtct gtgatccatt cttggacttc tttacggtga
    26821 agcacttcaa tcagtttttt gattttgtca ctgtcttcat cacctttgcg agtcgcaatg
    26881 atattcacgt aaggagagtt gtctttttca agtaatacgg catcttctaa tggattcaat
    26941 cctgcgccat aagcgaagtt tgcattgatt gcgactaggt caccttcatc attttggtac
    27001 gtagaagcta aaagtgatgg gtcgatcgta tggttgaact tcaagttctt agggttttct
    27061 gcaatatcat cgaatgttgc tgtttccaga tctactccat ctttgacttt gactagccca
    27121 gcatcttgta aaatcgtgat gatgcgtccc cagtctgatt cagaattcga agtgatgatc
    27181 gttgcaccat cttttagttc agaaacatct ttgacttttt tagagtacaa gcccattggt
    27241 tcgatgtgga cagcaccggc attgacaaag tcataccctt tttctttgat ttctttgttc
    27301 aaataaggaa tatgctggaa gtaattggca tcgatatcgc cttcttccaa agattggttc
    27361 ggtaaaacgt agtcatcgaa tttgacgatt tcaagagcga ttccttcatc tttcaataat
    27421 ggtttcacat gttccaaaat ctctgcgtgc ggtgtcggcg aagcgccgac tttcaatgtc
    27481 gtgtcgtctg ctttatttgc tgaatctttg ctgtcgctgt tgttaccgca tgctgctaat
    27541 cctacagtca gcaaaagcgc tgctgctaat ccaaaaatct tctttttcat atcctatatc
    27601 cccctatatc ctattatctt ttgtctgttt tcttagttaa gaaatcaccg attccttgaa
    27661 cgataaatac gattaataaa ataattaaag tcgcaacgaa tgtcactgtc agattaccac
    27721 gctggtagcc ttcctgccaa gcaagacctc caagtccacc tgcgccgatc gcgccggcca
    27781 tcgcagtaaa tccgatcatc gagatcgttg taactgttaa tccagaaatc aatgcgggaa
    27841 tactttcagg tatcaagacc ttccagatga tttcccagta acttgctccc attgcatctg
    27901 ctgcttccag tacaccaggg ctgacttcac gaaaagcaat ctctactaga cgggcataaa
    27961 atggtgctgc ggataaaaca agagctggaa tggctgcttg cgcacctagc atagtgccta
    28021 cgattgcttt agtaaatgga atgatcaaaa ccatcaggat cataaatggc gttgaccgga
    28081 aaatattact gatgatcgat acgattccat aaatgattcg agcatacggt ttgtttttgc
    28141 gtccaataga gtaaaggatc aatcccaaaa ctaatccgat gatcgtcact aagaccattg
    28201 agattaatgt catatatagt gtatcaagga tagcctgatt catcgtttcc gggttgattt
    28261 gtttaaaatc tagatatgtt tctgaaaagc ttttatccac gatggatcac ctcaattcct
    28321 actccttgtt ctttgatgaa cacttctgct tgatctaatt ctttggtttc accagtcatc
    28381 aagacagtca atgaaccaaa ggaaccttct ttcacttgtt tgatctttcc atacacaacg
    28441 ttgacatcga tgttatagcg tcgaatcgct tgggaaatga ctggctcgtt ggcatttctt
    28501 tcgctaaagg tcaaagttgc caaacggccg cttggatttt ctttgatgag ttcagctaat
    28561 agttctgtcg aatcagcttc tggttcgatg tcttgttgta caaagcgttt ggttacttct
    28621 tttttcggtt gtctgaagac agtcaatacg tctccttctt ctacgacttt ccccaactcc
    28681 atcacagcga ctttgttgca gattttgcgg atcacattca tttcatgtgt gatcaagacg
    28741 atggtcaaat tcaatttctt attgatcgct aacaataagt ctaatacttc ttctgttgtt
    28801 tgcgggtcca atgcgctagt agcctcatca caaagcagga tctcaggatc atttgccaat
    28861 gctcgtgcga taccgacgcg ttgtttctgc ccgccggaaa gttgtgaagg atatgcttgt
    28921 ccgcgtcctt ctaacccgac taaacgcaac agttcttctg cccgttcttt acgtttgctc
    28981 tttggtacgc cagctaattc cagcggcagc tggatatttt caagtacagt tcttgaccat
    29041 aacaggttga aatgctggaa gatcataccg attttctttc ggaatgtacg taattctttg
    29101 ttttttaatt ttgtaatatc ttgatcgttt acgatcactt cgccgctcgt gggaagctca
    29161 agtccattca ggagacggac taatgtactt tttcctgcgc cagaatagcc gacgattcca
    29221 taaatatccc ctttttcaac gtttagtgaa acgtcattga cggcttggat gtttccgttt
    29281 ttcccattga atgtcttttt gacattcgtt agttggatta atgacatgcc attcacatct
    29341 ttctcttatg atttttcaaa caaaaaagcc ttcgccctct tgccttaagc aaaaggacga
    29401 aagcttgaac ttccgtgtta ccaccttgat ttaccgttac ttcgcaataa cagcctcttc
    29461 cagtacttgg acttagcttc tttccgtata ctgtcgcgct gtaacgggca ctcccgtagt
    29521 aagtttgctt acgctcgctt actctgctct aagaccatct tccatctcat tttcgttacc
    29581 cattttcagc aaacagggct ctcttcaaac gtccgtgaca tgtactcttc ttttcaaagc
    29641 tttctcgttt catataggat tgcttatgat tatagcaact ggaagaatca gtgtcaactt
    29701 ttttcaagtg attttctgat tttataattc gtcaaattct tttggatcaa catctttgaa
    29761 acttaagatc cacgcattca tttcatctga atcattcaag atattgatat cttcaccgat
    29821 tttatcatta acagaagaaa ctgtacccgt tagcgggctg gcaaattcat tgaccgcttt
    29881 ttccgcttca acttcgatca gaggttcatc tttttttagc gattgtcctg cttttggcag
    29941 attggcaaac gtgatgtctc caagttcttc ttgcgcttca tttgtcaaac caacacagta
    30001 ttcttttcca ttaaataaga tccaaaggtt gtcctttttc ttcaaatgct tgcctgccat
    30061 tttatatcag ttctccttca taaatttttt cattgaatcc aattgcaaca agctggtcct
    30121 ctcgtaagat cagtggccgc ttgatcagca taccatctgt cgataagact tggctcgctt
    30181 ttgaagccgt aaactcgcct acttgatctt tcagtccaag ttcccgatat ttcatcccgc
    30241 ttgtgttgaa caggcgacgg attggtactt gactcgtttc tagccaagtc tcaatcgttg
    30301 aggccttcgg tacttctttg atcatatcaa cagtttgata actaacgcca tgctggtcta
    30361 accacgcttt ggcttttttg catgttgaac atttcgggta ccagtaaaag gtgtacaatt
    30421 ttcttacctc cttgaagatc ttgcaggtgc ttcattttgg tatctcatcg ataatatcaa
    30481 cccgataccg atcatgttcc ctaaaatcga agatcctccc tgactaatga aaggcaatgg
    30541 gatccctgtt aaaggaagta atccgatatt tgctccaata ttctcaaaga catggaacag
    30601 cagcatcatg atcaaaccgc ttgcgatata ggcgtaaaat tcattattcg tatcgaaaca
    30661 cacccgaatc atacgataga ttaaaataaa atacaagaaa atgacaaatg caccaccgat
    30721 aaagccgaag ttttcaccga caacggtaaa aatcatatcg gactcacgaa caggcacata
    30781 aatattgctt acgttgaatc ctttaccaaa caagccaccg gtaccaattg ccaaaagtcc
    30841 tcgggccggc tgataactca ttcctgacgt atcatggaaa gggtccagcc atgaatcaat
    30901 acgtgcaaac tgataagatt tgaagccaac tttgtaaagc aagtctcttc cgccttcagt
    30961 cgtaaccaag aagatcgttc ctgctccaac gactactgcc aagattacta caggtgcgat
    31021 gatgcgccaa gagattccag acatcaagaa aatcccgcca aagatcgcaa gaaagacaag
    31081 catcgttcca aagtcatctt gggccatgat caatgctaaa accggtattg tcacgatcaa
    31141 gagcttccca atcagccaaa agtccgattt catcgtccgt tcttttactt gcgtattatg
    31201 tttagttacg atcagtgcca tcatcaagat gtacgcaatc ttcatcaact ctgctggctg
    31261 gaaagtaaac gcaccgaatc gaaaccagtt tttagaccct gttgaagcag ctaaattctg
    31321 atcatagaat ttgagcaaga gtcccattac cactaacccc aaaccataaa agtaaggagt
    31381 cagtttccag atccatttgg aattcaaatg catgatgaca acgattgctg ccgctccaac
    31441 taaataccag acaacttgca tccctacgcc tttcaagact gctggattgt tcggatcatg
    31501 gctaagtgct acatataatg agagcagacc aatcaaacat aacagaaaga ctggtaaaat
    31561 cacgccataa tcaatacgat tatcgttcga agcttttaat tttttttcca tgtttcatcc
    31621 cttttcttaa aaaccatact gctgattatt atagcggtcc agttagataa tggaaagtct
    31681 ttccatagac atttgggaaa aattaacttt ccgtttgtgc agttgcttga gcaaatgcag
    31741 tacaaaagcc tactgcttat ctttagtgta tcatagaact ttttttgata catgcaatta
    31801 tctaccaact gagattctcc tcgctgtgag aagtttctgt gctttcattg tatcgaagga
    31861 tctcttcggc aatctctagc agctgatcag aaaccagatt ggttcgttgg atgaaataaa
    31921 aataacgatg gaaattcaac ggagtcattg gcacattttc tggaacagag cgcttagaca
    31981 aaatcgagcg accgattcct tccttcagca acgcaacaat tacatcgtta cttttcacga
    32041 tcatcttctt atcttggata ttcatctctt caaaataacg ctgcgtgtaa tgaaaaacac
    32101 cagagtttgc ttctcttaca agccacaatt tgctttttgg gtccccagcg atgactagct
    32161 ggtcttccat caaagagtat ctttgtacgc cggaagtctc taatggcttt tcgataaaac
    32221 caaaatcgga ttcatgtttc gctacttgtt ctaatgattc atgagaattc gcgatttcga
    32281 tctcaaaatg cactttagga aaccttttga tcagatgttt catcaactga ggcaaaggat
    32341 agacagcaaa ggtgtgggaa gcaacgattc gacatacttc ttcttcattt tgttcattga
    32401 gcaatttttg ctgagtttct tcccattctt ctaacaaaac cagtgtccgt tcatataata
    32461 agtcggcttg cttagttgga agcatctctt ttcttccgtt acgttgaaaa agatcgatat
    32521 tcaattcccg ctccaactgt ttgatttgat tcgagactgc tggttgagat aaaaacagta
    32581 cttctgctgc tctggaaaaa tttcttgttt catatactgc tcgaaaagtc gttaataact
    32641 taaacatggc accacttcca taacttttta tgataattac tataaaaact atttgattta
    32701 aatatacaaa aaaccatcta taatagaaat gtacaacaaa acagttgctg atccaactag
    32761 taacttagat gaagacaatc agctgtctgc ttgctcgtaa tcatacattc ctattcattt
    32821 tacaatgtat tcgttcatct tggtactaaa atctattaaa taaaaaggag aatattatat
    32881 atgaagaact ttttgaaaat tattccgatc ccgatctgcg ggttgatcct tgggttagct
    32941 tcccttggaa atctgtttaa agactatcac catgttgctt taggcaatct aactggcggt
    33001 atctctatga ttcttatgat attcattttt gttaaattgt ttatcttatt cgaacacacg
    33061 aaacaaacgt tgcatgatcc aatcatcgcc tccgtttcac caacttttac gatgtcactc
    33121 atggttattt gtacttattt tgtttcatat gaaagtattg caccaattgt caaattcatt
    33181 tggctgtgcg ctgttatctt ccaagtgatc cttgtctttt atttcaatta tcaccatgtt
    33241 atcaaagctg atctttcaat tgaagcaatt tatccaagct ggtttatcat ttatgttgga
    33301 tttggggtca tcactgtaac tgccgggaac ttcttcccgc ttattggaaa aattttcttt
    33361 tggatttcat tgatctgcta tgcgttctta ttgccgatca tcatcaaacg tgtctttttc
    33421 gtaagaaata tggctcatcc gacacgtccg ctgattacga tcgttgcagc acctggttct
    33481 ctttgcctaa caggttatct taaaaacttt gctgaaccta atttttatct tgtcgtagca
    33541 ttgttcgctt tatctcaagt attgtatttc gttgtgctgt ctatgcttcc acgtttgttc
    33601 aagcttcgtt tttatccaag ctatgcagcc tttacattcc cgcttgttat ctctgcaaca
    33661 gctatattta ctactgttca ttacttcaac agtttaggta tctatagtag cgtattggat
    33721 ttcttaaaag ttgcggaatg tctgtttgca agtgtagttg tcttctacgt tcttgctcat
    33781 tacgtacgtt tcttaattaa agaacatagc aaacatggaa aatttgtttc taaaaaaatc
    33841 gcttaataat cgattcaata ggttgtgaaa aagctgttct gcatcaagta ataagaacgg
    33901 ccaaacaaaa acagctgttc atgtttttga attggttggg cttattaccg cagatgcaag
    33961 cttttgaaca ccgtttacca agaggtcgta aaagaagtgg ccagcttcaa gaaataagaa
    34021 ggaatttacg aaaattgctt ctcaaatttt tgtgaaattt cggcttattt ccgaaaaagc
    34081 tacttctgga acaccgttta ccaagaggtc gtgaaaaagc cgcttagttt cgagtattaa
    34141 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
    34201 actggctttt gaacaccgtt tattcgaaac aagaggtcgt gacaagactt ttgtcacgac
    34261 ctcttgttct tttgtcaaaa tactggttta gtgctactat gttcgagtat gcttttagta
    34321 tttattgacg aaaggaaccg atcaaatgaa atcattgtca catccaataa aatctgtaaa
    34381 ggattcagcg gtccgcgaaa tcttacccgg tttactgctt tcttttgcca tcgctgcctt
    34441 cagcaggctt cttgctattt atctgccaca gttaggtgga gcgactattg ctattttatt
    34501 gggtatttta ttaggaaata ctttttttaa acagcctgtt ctagcaatcg gcacaaaatt
    34561 tgctgaaagc aaactattag aattctctgt ttttttacta ggtgcaactg tcacagctca
    34621 aacgattgct caaattggta taaaaggaat tgtttttgtg ttactgcaaa tgtcagtcac
    34681 tatcatcggt gcttacttga ttggtaaaaa actgcaattc agcgatactt cttctttgat
    34741 gatggctgga ggaaacgctg tttgtggttc ttctgctatt gcttcgatcg ccccttccat
    34801 ccatgcgaaa gaggaagaaa aaggacagat catcacacta gtcaatctac tgggtactgt
    34861 gatgatgttg actctccctt tccttggatt acagttgttt ggtggaaatc tcattgaaaa
    34921 aagtgcactt ttgggtggca cactccaatc tgttggtcaa gtagtcgctg gggcaagctt
    34981 acttgacaat tctgttgtcg aattcgccat gctatttaag attctacgta ttatgatgct
    35041 cgttgttgtt gtctatctgt ttgaaaaatt catgcacaag aaacaaccag ctctgtttga
    35101 aacgccaact gatacgcaga aaaaacgaaa attaccactt ccttggtatg tattagggtt
    35161 tgtgatcttt tgtttggtca acagcttgtt ttctttacct gtagttattg accaatcggc
    35221 acattttatc agcagctggt ttgagatcac tgctttagcg gcaattggtc tgcgtttaga
    35281 ctttgcaaaa ttcatgaaag aaggtacacg cttcttatct tatggattag ctgtcgggct
    35341 tctccaaaca gtgatggctt tactatttat ttggctgatc aaagtttaga atgaacatga
    35401 aaaaacagtt gtgattctcg catggaacaa tgtccgaatc acaactgttt ttaattttgc
    35461 agatatcctt ctaacaacaa caattggcgt ttgatttcaa ccccatctat tgcgtttccc
    35521 atatatcctg tcagttttcc attttgcccg atcactcgat gacaaggaat aacgattggc
    35581 aatggattgg ttcgatttgc ctgcccaatc gctcgcacag ctttcggact atcaacagca
    35641 acagctactt ctttatacgt tcggatttct ccataaggaa tggtcgacaa agctttccag
    35701 acattttgct gaaaaggcgt acctctcttt atagataaag gaacatcaaa ttcttttctt
    35761 tttcccgcaa aatattcttc aaactgttct tgtgtgcgcg ttaaaatttg ctgattcgct
    35821 gattcgcttt ctgaaattgg ctgaaaagat acagcagtca atccggattc atctgcatct
    35881 aaccataaaa agccgatagg tgtgtgtatt ttcattttgt ttgctcctgg tcagtagact
    35941 ggaacttcct cctttttctc tatccaaaac tacttgccaa ctaataaaaa ttgttcttaa
    36001 aagtttgata aaccgaggaa acatggtaaa ctaaatacgt tagtttacca aagaatagct
    36061 gttcttttcc ataaaatcaa atttaaaagg tgttatttaa ggtttattaa attttgaatg
    36121 taaaccatat ataaacatac gattgaaagg atagaaacga tgaaagtatc aattgttgtc
    36181 ccatgtttta atgaagaaaa aactgttcct cttttttttg atgaggttga aaaattcaaa
    36241 ggtgcccatg agttcgaata tttgtttatt gacgacggat caaaagacgg tacgttagca
    36301 gcaatcaaga agctagcctc agcttatcct tatgtccgct ttgtctcatt ttccagaaat
    36361 tttgggaaag aagcggctct gtacgctgga ttgcaagctt ctacaggaga tttagtgacc
    36421 gtgatggatg ttgatctgca agatccgccc gaactgcttc ctgagatgat caaccggatc
    36481 actacttctg atgtcgatag tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg
    36541 atacgcagtt tctttgcgaa aaaattctac cagttgatca ataaaatcag cgatacagaa
    36601 atggtcgatg gcgctcgtga tttccgcttg atgactcgtc aaatggtgga tgccgtccta
    36661 gaattaacag aatacaaccg attttcaaaa ggattattta gctgggtcgg atttaaaaca
    36721 gaatatattt cttatgaaaa ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg
    36781 aaattattca actactcgat tgatggtatc gtgaacttct cggatgcacc gttaacgatt
    36841 gcttcattta tcggcgcttt gtcttgtgtc ggttctggta ttgcaatttt gttcattatt
    36901 ttgcgggcat tgttgtttgg tgatcctaca tcaggatggc cttccatggt ctcgatcttc
    36961 ctgttcattg gtggaatcca attgttatgt cttggaatca tcgggaaata tatcgggaaa
    37021 atcttcttag aaacgaaaca gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag
    37081 ccaaatgaat tgaagcctca ccaataatat acgtcaaatg aagtaaacat ttttttaaat
    37141 gaaaaaggac tgtgacaaaa gtcttgtgta ccgaccccca aaagttagac caaaaaatct
    37201 aacttttgga ggtcggtatt ttttatggct aagtatactt ttgaacttaa attaaagatc
    37261 gttcatgatt atttggatgg caaaggcgga agtgattatc tggcaaagaa
//
LOCUS       DAPBCF010000023        36620 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.023, whole genome shotgun sequence.
ACCESSION   DAPBCF010000023 DAPBCF010000000
VERSION     DAPBCF010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 36620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.023"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            93..764
                     /locus_tag="RD508_001447"
     CDS             93..764
                     /locus_tag="RD508_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7736056.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            823..1263
                     /locus_tag="RD508_001448"
     CDS             823..1263
                     /locus_tag="RD508_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736057.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1275..1943
                     /locus_tag="RD508_001449"
     CDS             1275..1943
                     /locus_tag="RD508_001449"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDT7736058.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            2007..2630
                     /locus_tag="RD508_001450"
     CDS             2007..2630
                     /locus_tag="RD508_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HDT7736059.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2686..3072
                     /locus_tag="RD508_001451"
     CDS             2686..3072
                     /locus_tag="RD508_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HDT7736060.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3285..4676
                     /locus_tag="RD508_001452"
     CDS             3285..4676
                     /locus_tag="RD508_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HDT7736061.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            5287..5655
                     /locus_tag="RD508_001453"
     CDS             5287..5655
                     /locus_tag="RD508_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HDT7736062.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5835..6776
                     /locus_tag="RD508_001454"
     CDS             5835..6776
                     /locus_tag="RD508_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HDT7736063.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6845..7576
                     /locus_tag="RD508_001455"
     CDS             6845..7576
                     /locus_tag="RD508_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HDT7736064.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7720..9900
                     /locus_tag="RD508_001456"
     CDS             7720..9900
                     /locus_tag="RD508_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDT7736065.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9920..10402
                     /locus_tag="RD508_001457"
     CDS             9920..10402
                     /locus_tag="RD508_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HDT7736066.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            10418..11179
                     /locus_tag="RD508_001458"
     CDS             10418..11179
                     /locus_tag="RD508_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDT7736067.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            11310..12644
                     /locus_tag="RD508_001459"
     CDS             11310..12644
                     /locus_tag="RD508_001459"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDT7736068.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12951..13436
                     /locus_tag="RD508_001460"
     CDS             12951..13436
                     /locus_tag="RD508_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HDT7736069.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            13429..14112
                     /locus_tag="RD508_001461"
     CDS             13429..14112
                     /locus_tag="RD508_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDT7736070.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            14238..16883
                     /gene="polA"
                     /locus_tag="RD508_001462"
     CDS             14238..16883
                     /gene="polA"
                     /locus_tag="RD508_001462"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDT7736071.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16928..17764
                     /gene="mutM"
                     /locus_tag="RD508_001463"
     CDS             16928..17764
                     /gene="mutM"
                     /locus_tag="RD508_001463"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HDT7736072.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17728..18357
                     /locus_tag="RD508_001464"
     CDS             17728..18357
                     /locus_tag="RD508_001464"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDT7736073.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            18409..18741
                     /locus_tag="RD508_001465"
     CDS             18409..18741
                     /locus_tag="RD508_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDT7736074.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            19053..19544
                     /gene="nrdR"
                     /locus_tag="RD508_001466"
     CDS             19053..19544
                     /gene="nrdR"
                     /locus_tag="RD508_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HDT7736075.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19567..20940
                     /locus_tag="RD508_001467"
     CDS             19567..20940
                     /locus_tag="RD508_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDT7736076.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20940..21866
                     /gene="dnaI"
                     /locus_tag="RD508_001468"
     CDS             20940..21866
                     /gene="dnaI"
                     /locus_tag="RD508_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HDT7736077.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21995..22435
                     /locus_tag="RD508_001469"
     CDS             21995..22435
                     /locus_tag="RD508_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDT7736078.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            22579..23280
                     /locus_tag="RD508_001470"
     CDS             22579..23280
                     /locus_tag="RD508_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HDT7736079.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            23277..24398
                     /locus_tag="RD508_001471"
     CDS             23277..24398
                     /locus_tag="RD508_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDT7736080.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            24413..25645
                     /gene="pepT"
                     /locus_tag="RD508_001472"
     CDS             24413..25645
                     /gene="pepT"
                     /locus_tag="RD508_001472"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDT7736081.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            25777..26685
                     /locus_tag="RD508_001473"
     CDS             25777..26685
                     /locus_tag="RD508_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HDT7736082.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            26720..26992
                     /locus_tag="RD508_001474"
     CDS             26720..26992
                     /locus_tag="RD508_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HDT7736083.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            27003..28049
                     /locus_tag="RD508_001475"
     CDS             27003..28049
                     /locus_tag="RD508_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDT7736084.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            28300..30909
                     /gene="clpB"
                     /locus_tag="RD508_001476"
     CDS             28300..30909
                     /gene="clpB"
                     /locus_tag="RD508_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDT7736085.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(31060..31746)
                     /locus_tag="RD508_001477"
     CDS             complement(31060..31746)
                     /locus_tag="RD508_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736086.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(31724..32218)
                     /locus_tag="RD508_001478"
     CDS             complement(31724..32218)
                     /locus_tag="RD508_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HDT7736087.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(32238..33458)
                     /locus_tag="RD508_001479"
     CDS             complement(32238..33458)
                     /locus_tag="RD508_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7736088.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            33605..35440
                     /gene="lepA"
                     /locus_tag="RD508_001480"
     CDS             33605..35440
                     /gene="lepA"
                     /locus_tag="RD508_001480"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDT7736089.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(35534..>36620)
                     /locus_tag="RD508_001481"
     CDS             complement(35534..>36620)
                     /locus_tag="RD508_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7736090.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT        12191 a         6474 c         7821 g        10134 t
ORIGIN      
        1 aaatagtaaa tttttatgaa attctactct aagcatcaga ctttcttttc aaaatatgct
       61 attttaaaaa tgatgaaaaa agggggagaa aaatgaattt tttagttgtt ttaaaagata
      121 ctctgattga gcgatctaca tttctatatg ttcaattgca ggaaaataaa acattgctgc
      181 atttttcacc agagttccat ctagaggggc taacattagg agaaatctat caagcagaag
      241 ggctgtcggc tgttttgcac ttttttaagg tagaattgga attaccagta aaagattata
      301 tcgagctttc tcttgaatct tgggatcgag cagtggttga actgtttcca gaaggtttaa
      361 tgatcgatac aaacgatggg aagatccatc tgactgcagc agaactgcaa aaacaaatgc
      421 gttatcaaat agatgacgaa aattcttttt ctatttttag acgtcagcaa aagattctaa
      481 aaagcttttt aaaagtgatc agtaaaaaac ggaatctgat caaaacgaca cagctgttga
      541 aaaaatatcc aggtctgctt cacacgtcta ttcaatttcc tcaattgatt acgatgatcc
      601 atcgttttat acgtatgcaa cagctaccat ctaagaagct gtttcttcca ttgacggaca
      661 catttcgagt agtcaacaga gaagataaaa agaaagtgat tgtgattgac tttaccagaa
      721 atcggaatgt ccttcaccaa gttgcaatgg aaaaggccaa ttaaggcttt ttctttttgg
      781 atttttttgt cataataaat attagatgat ggaggagata atatgatgca aacatggtta
      841 gaaaggctaa tacgatttca gcagaactat cacaaactta tgcagggaag atatgcgaaa
      901 tttgatcagt tgaatcgcgg tctattgatc gctgcgcttg tctttagttt gctaagtcgt
      961 tggttgccct atagaatcgg acaattgttg ttcatcgtct ttttcggatg gatgatattt
     1021 cgtttcctat caaaaaaaat ctaccccaga ctaaatgaga atcaacgtta tttgaaatat
     1081 cttgatagag tcaaagaaaa atatcatcag ataaaaaaca aaaagcaagt caaaatggat
     1141 cgaaaaagtt atactttttt tgagtgcccg aattgtcatc aaaagcagcg tgcacctaaa
     1201 ggaaaaggac gaatacgtgt gacatgcaaa acatgtggta taaaattcga aacgaatgtt
     1261 taagggagaa aagaatgaaa ttagtattat tacgtcatgg cgaaagcgaa gcaaattttg
     1321 aaaattactg gacaggatgg ctagatgtcg ccttaacaga aaaaggaaaa gaacaagcag
     1381 cagttgccgg tcaaaaaatg cttgaagccg gacttcaatt cgatgccgtt tatacctctg
     1441 ttttgaaacg tgcgattctt accggacaag tcgcactaga agaaatgggt cagttatggc
     1501 ttcctataat aaaaacatgg cgtctaaatg aacggcatta tggggatctt gtgggtaaaa
     1561 acaaagataa gatgaaagaa atatacggaa aagatcaagt aaaaacatgg cgcagaggat
     1621 atacggaagt tccgccgtta accgcagaaa atagatttga ccgcagatat gatcacttgg
     1681 atccgcattt gatcccatac ggagaaagtc tggaaatgac agtgaatcgg atcattccct
     1741 tatggcaaga tcatctagca ccaaaactaa aagatcggca agatttacta gttgtgggtc
     1801 atggtaatag catccgagca ctgacaaaat atttagaaga tgttcctgaa gatcaaatgg
     1861 atacgatcga tatcccaaat gcacaaccaa tccagtatac attagcagat gatttgacaa
     1921 ttctggacaa aaaaatactt taaagaacac ctttatctaa aagtgagaga tagaaaaaag
     1981 aagcaaagga atggaacaaa aggaacatga aaaattatat atgggacttt gatggtacat
     2041 tgtttgatac gtatcccgca atggtagatg gtgcatggca agcactaaaa gattttggta
     2101 tcagtatgga caaaaaagaa atctacttca aaatgaaaaa gtattctact agttatttga
     2161 tcaatgaatc aaacttgaat gccagagagt ttaatgaatt atttcaccga tatgaaaaag
     2221 aaagtacgga agtttcccgt ccatttccag aaacgaaaca agtactggaa atgctaaaag
     2281 acaacggcgg tcgtcatttc atcctgaccc accgtttgac agaatcaaca tggggcctgt
     2341 taaaagaaca tcgattggca catctgattg aggaagtagt agggatcgat caggactttc
     2401 ctcgtaaacc tgatccagca tctttaaatt atttgatcga tacttttcat ttagaaagaa
     2461 cagacacgat gatgatcggc gatcgtcgtt tagatatcga agcagggaaa aatgcaggag
     2521 tcgctacttg tctttacgac atcgatcatt ttctgggtga gatcccggca gattatgtgg
     2581 taggaaatct gaatgaaatc cttaccttgc agagcatcat taaaaagtag tatccccttt
     2641 caaaggagat atgttataat tttcataaag gagtgataaa attatatgga aatcagaaga
     2701 caaaaagaag ttgtagaagc atttcattat gatatgagat tgccgaacca agaagtagaa
     2761 acagatttga aagtaggctt ctcgccttta aaagaaacga tcgaaaacta tccgaaagaa
     2821 catagcatcg taggagcacg cttagagttc cgtttagtgt ttgatacata tgttttatct
     2881 ggaagtgtga gtcagatcaa tcatatcctc aatcggaaaa ttgaaggtca aaatgatgtc
     2941 acacaagaag aagtggacga gctagtagca ccgttattcg atatcgtacg ccgaatgtct
     3001 tatgaggtga cagagatcgc cttagatcag cctggggtaa aattgaattt tcaatcagaa
     3061 aaacaagaat agacagtaaa aacatacctg cgatagatta aagctatcac aggtatgttt
     3121 ttttattact aattgtaagc aaaaagaatg tcatttcgat aaaaatcgtc taaaatataa
     3181 aagtcactga aaaaaatttt ttcaggagga tggttgaaga atcattctcg ggaaccttta
     3241 cttccttcga tggacttgtc attaataata tgaggaggag aaaaatgaca acactcatca
     3301 cagttttagt ggttctagtt tttgcggcat tattatatgt gttctatcgt atgcaaaagc
     3361 gccatacaaa attttcaaca cgcgtcttta cagcattagg agttggtatc gtctttggcg
     3421 gtctgcttca attgatcttt ggtgtagacg acaaagtcgt tactcaatca atggaatgga
     3481 tcgggattgt aggtcaagga tatgtatcat tcttgcaaat gctagttatg cctttagtgt
     3541 ttatttcgat cattggtgca ttcacaaaaa tgaaagtttc tgaaaagcta gggaaaatta
     3601 gtgcgactgt attgacttct ttacttggaa caacagctat tgcagcattg atcggaattg
     3661 gttcaacaat gctgttcgga ctccaaggag ctaaattcac acaaggagct gcagaaacag
     3721 cacgaatctc tgaactggca acacgtcagg aaacagttga aaacttatcg attccacagc
     3781 agattttatc ctttatccct aaaaacgttt ttgctgattt agcaggtagt cgtgcaacaa
     3841 gtacgattgg agtcgttatt ttcgcggcat ttgtcggaat cgcttatcta ggcgtgaaaa
     3901 gaaaagcgcc aaaagaagca gcattctttt cagatttagt cgacagtctg tataaaatca
     3961 ttatgcggat cgtgacgctt gttttgcgtt tgacacctta tggagtattt gctttgatga
     4021 caaacgtttt ggcaacaagt gattttgcag ctatcgtcaa tttaggtaaa tttgtcgttg
     4081 cttcttacgt agcattgctt gctgttttga ttgtccactc actgattttg attggtgcaa
     4141 aagtcaatcc aatcaactat ttcaaaaaag cctttccggt attgagcttt gcgtttactt
     4201 cacgttcaag tgctggagct ttgccattga atatcgagac tcagacaaaa gctttaggag
     4261 tagatgatgc aacagctaat ttctcagcaa gttttggttt gtctattgga caaaacggct
     4321 gtgctggcgt ttatccagct atgttggcaa cgatcgtcgc accagcagct ggagtgaatg
     4381 tctttagttt ggaatttatt ttgatgcttg tggcaattgt aacaatcagt tcttttggtg
     4441 tagctggagt cggtgggggc gcaacatttg cttcactgat cgttttaggg gcaatgaact
     4501 tgccagtagc aatcgttggg ttagttatct ctgttgaacc attaatcgat atggcacgta
     4561 cagcagtaaa cgtcagcggt agcatggtag ctggtatcgt gacaagtgca cgcatcaaag
     4621 atttagatcg cgatgtcatc aatgatgatt ctaaagtgat cgatgtgaat gcatagtcaa
     4681 aaagaggttg tgatagaagt ggtcagcttt aagaaataag aagaagtttc ctaaaaatag
     4741 tttctcaaat ttttgtgaaa tttcggctta tttccgagaa gctacttctg aaacaccgtg
     4801 aataagaggt tgtgaaaaag ctgccctgca tcaagtaata agaacagcca aacaaaaata
     4861 gttcctcata ttttacgttt ggttgagctt attaccgcag atgcaagctt ttgaacaccg
     4921 tttaagaaag aggtcgtgag cctgccgttt cactctgagt cacaaagagc aatttcaaaa
     4981 aatagcttct catgtttgtt gaatattgtg tcttgtgacc gaggagttgt caggagaaca
     5041 ccgtttacca gaggttgtga cttgttttta gtcacgacct ctttttttat ttattccata
     5101 taaatacaca ttatttattc cgaaaagtga aagcgcaaat aacaaaaaca accaacttat
     5161 ttattattaa agaaaagcgt atttaagtag gacgattctg ttgagagctt tcgtagattt
     5221 tcccattttc ctatggtaaa ctgacaaagt tgagaatgtt agaacagatc gtttaggagg
     5281 aaacagatgt ttacgaatga aataaaaatc atgctttatg tggacgatgt agaaaaaaat
     5341 gcaacgtttt ggagagcagt tggctttgcg gaaaaagatc gtcaagaaat ggatgggacg
     5401 cttataattg aagtaggagt tgaggacagt caaacctcat ttctgttata tgatcgagca
     5461 tttgttgagt cccattcacc tggcacagct actagtgccc catctttgat gttttacagt
     5521 aaagatatct ttggactata taaaaaaatg cagacgcaat cagtcacatt aggtgatatg
     5581 gtacagcttg gagaagaata tgtctttaac tttgctgatc ccgatggcaa ctactttgcg
     5641 gttacaggta aataatagaa ataaagactt tgtttttctg tgcgaaacag gaaagcgaag
     5701 tctttttaat tcaaataata atattatgta aacaaaaaac tttccatgcg taattataca
     5761 caagcaaata aatcgtcaaa tgcgaacgcc ttctttatac tgtttaggaa cgaaaagaag
     5821 gaaggaagaa atacatggat tatcaagtac tgctttatta caattataca aaaatcgaag
     5881 aaccagagga atttgccaaa aatcatttag ccttttgcaa atctttggat cttaaaggtc
     5941 gtattctagt agctgaagaa ggaataaatg gtactgtgtc tggaaccgtt gaaaacacga
     6001 ctgcctatat gaaagcaatg aaagctgatc ctcgatttgc tgatacgatg ttcaagatcg
     6061 atccaagcga aggacatgcc tttaagaaga tgtttgtaag ataccgtcca gagcttgtaa
     6121 gtttaaagct agaagaggac attgatccaa accaagtgac aggtgcctat ctttcaccgc
     6181 aagaatttaa agaagctatt ttagatgaac agacagtggt gattgatgca cggaatgatt
     6241 atgaatatga cttgggacat tttcgagggg ctgtacgccc agatatacgc agttttcgag
     6301 agcttccaga ctggatccgc gagcacaaag aagaatttat ggaaaaacgg gtagtgacct
     6361 actgtactgg tggcattcgt tgcgagaagt tttctggttg gcttgtccgt gaaggattca
     6421 aagatgtcgg acagctgcat ggcggtattg ctacttatgg taaggatcct gaagtccaag
     6481 gagaattatg ggacggcaag atgtatgtgt ttgatgaacg gatcgctgtc gatatcaacc
     6541 aagtagataa acaaatcgtc ggtcgcgact ggtttgacgg aacaccatgt gaacgatata
     6601 tcaattgtag caatcctgag tgcaatcgtc agattcttgc ttccattgaa aatgaagaaa
     6661 aacatttagg agcatgtagc atagagtgtg cgaaacatcc gcgcaatcgc tatgttcaag
     6721 accatggaat ctctccagaa gaagcagaac tgcggtttac agctttaatt aaatagaaaa
     6781 caatagtttt gattgtcgac catttccaat atgcgctata ctagcgttga ggatggtgat
     6841 ccacatgaaa tcattgattt atgctattgg ggatgtccat ggcaaacatg agctttttga
     6901 aaaacttatt cactattatg atccaaagat ccatcagctt gttttattag gggatctcaa
     6961 tgatcgaggt cctcgtacaa aagaatgttt tttattagga aagcaattag tcgaagaaac
     7021 aggagccatt tacctccggg gaaaccatga agaatatttt ttgcaatttc tgcaatcacc
     7081 ggaggactgg tatgcgcctt atatgagaaa tggtggaaaa gaaacgtttg aaagcctgat
     7141 tcacccaggg gcatcggagg aatactcccc aactgaaatc tcgatgatga tccaatcgag
     7201 atattcagaa ctgattaaat ttttagtcca gcgccccttg tattatgaat gggaaaatta
     7261 tctttttgtc catgccggtg tggatttgac aaagaaagac tggcgtaaga caagtctaag
     7321 agactttatt tggataaggg aaccatttca tgaagggaaa aacaatacag gtaagacaat
     7381 tgtatttgga catacgatta caccaatgct ccatggagat atgcagacaa cagacctctg
     7441 gattcaggat cataaaatcg gaatggacgg tggggctgta ttcggagggt cattgcatgg
     7501 ggttgttttt gacaaggaag gtattcttca agatattgaa tatcagaaca acgaaggacc
     7561 ttggcatgga atctgactaa tggaaagaat gaaggagctg tgactttgtt gcggctcttt
     7621 ttatttttat agagaatatt gtttctttca gtagtttaac ccaggataaa aagtatgata
     7681 gaataaagaa gcaattttta gcagaaaaga ggcattttaa tgacggaaaa tttgaaccag
     7741 acgatcattc agcttgtaca aaaagaactt tcagactatc gtcctaagca gttgactact
     7801 gtacttaatt tgttaaatga aggaaacact gttcctttta tcgcgcgtta ccgaaaagaa
     7861 atgactggaa gtcttgatga agtccagatt cgtgaaatcg aagagcggta tgcctatctt
     7921 gaaaacttag aaaaacgtaa aactgaagtg attcggctaa tcgatgaaca agggaaactg
     7981 actcccgagt tagaagcaga aatcacccaa gccgtgaaaa tgcaacaagt ggaagatttg
     8041 tatcgtccat acaaacaaaa acgacggaca aaagcaacga ttgctaaaga aaaaggactt
     8101 gaaccactcg cgaagtggct gatgcagctt acagatggag aggtgcaatc tgaagcagaa
     8161 aaatatattg acaaagaaaa agaagtctct tctgccgaag aagcgttgca cggtgctcat
     8221 gagattattg ctgaacaagt cagcgataat gcaaaatttc ggacttggat tcggtcttat
     8281 acgtataaca aaggtatgta tgtcagcaat gtcaaggatg agcaagcaga tgaaaaaggc
     8341 gtatatgaaa tgtattatga ctttgcagaa cccgtccata aaatggtttc tcatcgaata
     8401 ttagctacta atcgtggaga aaaagaagat attctgaaag tattctttca agtagatgaa
     8461 gcagcaattt tagcttactt ggatcgccaa atagtcaaaa atcctgcctc tccttcttct
     8521 tcattcgtca gagaagccta tcaggatagt tataaacgct ttattcagcc agcaatcgag
     8581 cgagaactgc gcaatgaatt gactgaaaag gcagatgagc aagcaatcgc tattttcggc
     8641 gaaaacctcc gtaatctttt gttgcaaccg ccactaaaag gtaaagttgt cctgggattt
     8701 gatccggctt atcgtactgg atgtaaacta gcagtcgtag atgcgacagg gaaagtttta
     8761 gcaatcgaag ttatttatcc tcataaacct gcagcgcaag caaaaagaga agctgctgga
     8821 ccagctttta tccaattaat taataaatat caagtagata tggtagctat cggaaatggt
     8881 acagccagtc gggaatctga actttttgtg gctgagcagt tgaaatccgc cgaccataaa
     8941 acctattacg ctatcgtcaa cgaagcaggc gcttctgttt actccgctag cgaaattgca
     9001 cgaaaagaat ttccgcatct acaagttgaa gaaagaagtg ctgtttctat tgcccgtcgc
     9061 ctgcaagatc ctttagctga attagtcaaa atcgatccta aagctgtcgg agtaggccag
     9121 taccaacatg acgtttctca aaaacgtttg gctgaacaat tggattttgt tgtggaaaca
     9181 gcggttaacc aagtaggtgt ggatgtgaat acagcaagcc cgcagctctt gcagcatata
     9241 tcaggattga ataaaacaac tgcccaaaac attgtcattt atcgtgaaga aaacggagaa
     9301 ttcaccgcac gaactcaatt gaaaaaagtg ccacgcttag gaccaaaagc atatgaacaa
     9361 gcaatcggat tcttgcgagt ccctggtggg aaaaacattt tggacaacac aggtatccat
     9421 cccgaaagtt attctattgc aaaagaaata ttaacttcag tccaactttc agaaaaagag
     9481 cttggtacag aagaagcagt agaaaaattg acacgattat ccgtagagaa actggctgaa
     9541 agcctatcag tcggagaaga aacgttagcc gatattttag ctgggctgac acaacctgga
     9601 cgagatatgc gtgatgagat gccagcgccc ttattacgta cagatgtatt gagtatggaa
     9661 gacttgaaac cagggatgga attgactgga acggtccgta atgtcattga cttcggcgca
     9721 tttgttgata tcggtgtgaa gcaagacgga cttgtccata tatcgaaact cagcaaaaaa
     9781 ttcgtcaagc atcctacaga tgtcgtgtca gtaggagata tcgtaacagt ttggatagaa
     9841 caagtcgata cgaaaaaagg cagaatcagt ttgacgatgc tttcccctta tgaagagtaa
     9901 caatgaggag taacaaaaat tgacacaaga agaactgcag cagttagtag aagagatatc
     9961 attaaaaagc ttccagcttc ctttcaagca ccaagcaatg ttcaatccac gcttacgtac
    10021 aactggcggg cgctatcatt taaacgatca tcatttagat tttaatgcga agctatttga
    10081 agagtcagac gaagagacga ttgcaggaat catcaaacat gaactttgcc attatcatct
    10141 tcatctagct ggaagagggt atcagcataa agatatggat ttcaagtatc ttttgaaaaa
    10201 aacaggaggg ttgcgctatg caccagcctt gacgaagaaa cagataaaga tggagtatta
    10261 tcgatgccaa gattgttctg ccacgatctg ccgcaagaga agaatcgatg tacgcaaata
    10321 tcgttgtgga agatgtcatg gagaaatcaa atggattgag acaaaaagag aagactttaa
    10381 tgaagcacaa aaaatcagat gaaaggatag aaggcctttg gaaaaaagtg agcagaggaa
    10441 tctaaaagac tggaatcagc tattaaattt tttagccgca cctgaagagg gaaattttga
    10501 ggaactgacg gcacctacac ttattttagc tggaaactgt cttcctatct tagctgataa
    10561 agcagcacaa atgtatttaa atggccaagt agatcaattg tttttggtcg gaggggtggg
    10621 gcatgcgact agaatccttt atgagaattt tgaaaagcaa ggatttcatt ttgaagatgg
    10681 catgagtgaa agtgaaatct gtcgtcagta tctaaaagaa gtctatgatt tgcccgataa
    10741 ggcttttctg atagaatcga agtctacaaa ttctggagag aacgccactt tttcactgga
    10801 gattcttcat tccttaggag ctgtaccaga aaaaatctta ttgatgaatg atccgacact
    10861 gcaacgcagg actcgagcaa cttttgagaa agtatggcaa aatgaacaaa ctattttcgc
    10921 gaatgctgtg ccatttgtgc cggaaatcct tcacttttct gaagagatca tctttacagc
    10981 aaaagaactg aatcatcaat ggcctaagga atatttccat gcgctagtat taggagaaat
    11041 ggaacgtctc catgacgatg agaacggcta tggtccgaaa ggaaaagatt ttattcctca
    11101 cattgatata tcagaggaag tttggtcttc ttacaccaga attaaagagt caataaaaac
    11161 ggatttttct cgtacttgac cattttagca agcgaatcct cctttccaaa taaatttggt
    11221 tgaaattttc aatcgtttat aagataatga ggagcgtgtt gaatgtaata gctaaaagaa
    11281 tggacgctag ataagagaag aggattcaaa tggaaaatca aaataaattg tatcattttg
    11341 ttggtatcaa aggttcagga atgagctcct tggctcttgt tttacatgaa caaggtctaa
    11401 atgtccaagg atcagacatt gaaaaatatt tctttacaca aagagattta gaaaaagcaa
    11461 atatcacgat tctgccattt aacgcagata atgtaaaacc agggatgacg atcattgcag
    11521 gaaatgcatt tcctgattca catgaagaaa tccagcgagc aaaagaatta ggtttggaag
    11581 tgattcgcta tcacgacttt attggtcatt ttatccaaaa ttatacgagt atcgctgtaa
    11641 caggctctca cggaaaaaca agtacgactg gactgctctc tcatgtattg agtggtgtcc
    11701 gtccaacaag ttatctaatt ggagatggaa caggacatgg tgatccgcaa gcggaattct
    11761 tttcatttga ggcctgtgaa tatcgccgtc atttccttgc ctattcacca gactatgcaa
    11821 tcatgaccaa tatcgatttt gatcatccgg attattatac aagtatcgac gatgtattta
    11881 cagctttcca aacaatggct ggacaagtga aaaaagctat ttttgcgtat ggtgacgatg
    11941 cttatttacg caaattaaaa gcaaatgtgc cgatttatta ttatggtgtc acagaaaacg
    12001 atgatatcca agcacgaaac atcgaacgca caacttctgg ttctgctttt gatgtctatc
    12061 atggggatga atttgttggg cacttcactg taccagcatt cggtaaacac aatatcttaa
    12121 atgctttagg tgttattgca gtagcttatt tcgaaaaact ggatctgaaa gaagttgcag
    12181 aagaaatgct gactttccca ggagtaaaac gtcgattcag tgaaaagatc gtagcagaca
    12241 tgaccgtagt cgatgattat gcgcatcacc ctgcagagat caaagcaacg attgatggcg
    12301 cacgccaaaa atatccagat aaagaaataa ttgcagtttt ccaaccccat acgtttacgc
    12361 gtacgattgc attgatggat gaatttgcag aagcacttga tttagctgat aaagtttact
    12421 tatgcgatat ttttggttcg gctcgggaag aacaaggaaa cgttaagatt gaagaccttg
    12481 gagcgaaaat caaaaaaggt ggagaagtca tcaaagaaaa taatgtatct ccattgttag
    12541 attatcatga tgcagtagta atcttcatgg gtgctggaga tgttcaaaaa tttgaacaag
    12601 cgtatgaaaa acttttaagc agcacgacga aaaatgtact gtaatacaat tactgcagtg
    12661 tccttataaa aatagaaaga gggggagtgg caaaaatctt gccaagcccc cttttttgca
    12721 acttatgata aacggtgttc aaaagcttgc atctgcggta ataagcccaa tcaaatcaaa
    12781 aacatgagaa gctgtttttt cttggctgtt cttattattt gatgcaggac agctttttca
    12841 cgacctctgt aaactatagg aatctgttaa atcaagggag cagaacttgc cttttacgct
    12901 acttttggta caataatgta tgattaaaaa taaactggag ggtttctatc ttgaacatag
    12961 gtaagccgag aaaactagga aaaacaataa atgaaatcga ggaaggcgac tcgttatcct
    13021 taacagaatc tattgaagat aaccagcttt tgctgtattt gggattgacg aatgatgcaa
    13081 atcctttgta tatccaacat gactttgcac aaaaaacaga atatcaacag ccaatcgttc
    13141 catcagtgat gctgatgggg atcatcacaa gtgcaatttc aaagcatctt cctggaccag
    13201 gatcacatgt tgtcaatttt tctgtcaatt ttattgaacc ggttttccat tatgaaacac
    13261 tgacttttca gtttgaggtc ataaaagtag ataagatgaa ggatgtggtg acgatttctg
    13321 tagaagcgga gaatacgaac gaagatcgtg tgttggatgc tgtcgttatg gtccaaccgc
    13381 cacaagttcc tgaattggaa atagcaatcg aaagtgaagg tgaattgaat gaataatcca
    13441 agtacatcaa tgtcaggtat caatcgtttt tatgcaaaag tttatggatt tttaggtatg
    13501 ggacttgccc ttagtgcagt cacttcttac ttggctcttt gggtatttcc tttgcaatta
    13561 gcaactttta tcaataattt tccactaggc tttgtgggtc tgtggatcgt tgaactgatt
    13621 ttagtaatgg ttctaggcgt aaaagcacaa aagaatccga gcttagcaat cggtggattt
    13681 attgcctact ctcttttgaa tggcataaca ttagcggtta ctcttgcata ctacgatatt
    13741 ggaacagtaa cgcaagcttt cttgacagct actttgatgt tcatggggat gtctgttgtc
    13801 ggagtaacaa caaaaagaga tcttagcggg gttggaagag caggacaggc agctttaatc
    13861 ggagtgatca ttgcactagt cttgaacatc ttcattttga gaagtagcgt agttgagctg
    13921 ttcatctccc tactgttagt cgtcatcttt gcagggatta cagcttatga taaccaaagc
    13981 atccgtaata tctatgtcca gacaaacgga acagcacata gtggaattgc tgtattcatg
    14041 gcattgaagc tgtatttgga ctttatcaac ttgttcttgg cgtttctgag aatctttgga
    14101 cggaacaact aaaaaagaaa aaaattcatc agttggggct ataccgaatt atttggtatg
    14161 gtcccgcttt ttcttttcgc attccgcagg attctttgtt agaatgaata agaactttac
    14221 agtaaggagt taagaagatg acaaaaaata aattattact cgttgatggg aacagtgtgg
    14281 cttttcgcgc attctttgcg cttcacaatt ctcttgaacg tttcaaaaat agaaacggtc
    14341 ttcatacaaa tgcaatctat gcattcaata cgatgtttga aaatgttatg caaaaagagc
    14401 aaccgactca tgttctggtt gcgttcgatg caggaaaaac gacttttcgg acagaaatgt
    14461 atgcggagta caaaggtgga agatccaaaa cacctggcga attcaaagaa caaatgccat
    14521 atatacgtga tttgttgaca ggactagggg tacagtatta cgaattgccc aattatgaag
    14581 cagatgatat tatcggtact ttggcagaaa aagtagacaa agatcaattt gatgtcgtcg
    14641 tgctttcagg tgatcgggat ttgactcaat tagctagtaa agaagtaaaa gtggatatca
    14701 ctgtaaaagg tgtcagcgat atcgaaagct atacaccaga acatgtagcg gaaaaatatg
    14761 atgggttgac gccaaaacag attattgaca tgaagggact agccggagat gcctctgaca
    14821 atatccccgg tgtgactaaa atcggtgaaa aaacagctat caagctattg aaacaatatg
    14881 gctcagtcga aggaatttat gaacatatcg atgaaatgaa gcaaagcaaa atgaaagaaa
    14941 atctgataaa tgacaaagag caggctttct tatcgaaaaa attggcgacc atcaatactt
    15001 cagcgcctgt ggatgtctct atcgactcat tgaagtatga agggaaaaat ctcgataaac
    15061 tcgttccgtt ttataaagaa atggatttca atcagttcct ttctaaattg aatatcgtag
    15121 aagaagaagt aaaaatggat gatattttgt ttgaagtcgt tcatgaattc aaagaggaaa
    15181 tgtttactac ggatatggcg ttgtacgtgg aaatgatggg cgacaattat catacagagg
    15241 aaatcgtcgg agtagcgtgg gggacagaaa agaaaattta tgtcacgaac gatctatctg
    15301 tattcgaaaa ccgagcgttc cattcttgga tcactgatcc gactcggctg aaaaaagtat
    15361 atgatgcgaa acgaacttat gttgctttaa accgctatac tggaaaaacg aaaggaatcg
    15421 attttgatgt cttgctaggt gcataccttc tcgatacgaa tgaaaaaagc acagatatcg
    15481 aaggaatagc tgctcattac ggatacaacg atatccaatc agatgaagct gtatacggca
    15541 aaggggcgaa aaaaggttta ccagaagaag aggaactctt ttttgctcat ttagcgcgaa
    15601 aagtagctgc aatcaatgcg ttgacaccaa aattgagcca agaactggca gaaaaaaacc
    15661 aagaagatct tttccggaaa atggaactgc cattgtctat cattttggca gagatggaaa
    15721 taagcgggat caaagtagat gcgactcgct tacaagaaat gaagggcgag ttctctgctc
    15781 gcttaagaga gatcgaacaa aaaatctacg aagaagccgg cgaagaattc aatttgaatt
    15841 caccaaagca attaggagtg atcttatttg aaaaaatggg attacccgtt atcaaaaaaa
    15901 caaaaactgg atattccaca gccgtagatg tactggaaca gcttcgtgaa caagcaccaa
    15961 tcgtagagga tatcctcacc tatcgtcaaa ttgcaaaaat tcaatctacc tatgtcgagg
    16021 gactgctgaa agtgatccaa tcagatggaa aagtgcatac ccgttatgtc cagacattga
    16081 cccaaacagg acgattaagc tctgttgatc ctaatttgca gaacatcccg attcgattag
    16141 atgaagggag aaagatacgt caggcatttg ttcctagaga aaaagactgg ctgatttatt
    16201 cttctgacta ttcacaaatc gagttacgcg tacttgcgca tatctcaaat gatgaacatt
    16261 tgaaagctgc cttcctagaa ggtcaagata tccatgccag cacagcgatg cgtgtatttg
    16321 gaatcgaaaa ggcagaggat gtcacaccaa atatgcgtag gcaggcaaaa gcagtgaatt
    16381 ttggtatcgt gtatggcatc tctgattacg gactttcaca aaatctagga atcagccgaa
    16441 aagcagcaca gcaatacatc gatacgtact ttgaaaaata cccaggtgtc aaagaatata
    16501 tggaaagaat cgtacgcgaa gcaaaagacc aaggctacgt cgaaacgctg tatcaccgcc
    16561 gtcgatatct gccagacatc aattcaagaa attacaatat ccgttctttt gcggaacgaa
    16621 cagctatcaa tacaccaatc caaggaagtg ctgctgatat tttgaaaatc gcgatgatcg
    16681 aattggataa acgattaaaa gaaacaggtc ttcaagctac gatgctgtta caagttcatg
    16741 atgaacttgt cttcgaggta ccggaaaaag aacttgaatc attagataaa ttggtgaagg
    16801 aagttatgga acaagctgtt tctcttcatg taccactgat cactgacagc agttggggaa
    16861 aaacgtggta cgaagcaaaa taaacattgt ttaagacaga gcaatataat gaaggtgaaa
    16921 agaaaaaatg ccagaattac cagaagtaga aaccgttcgt aaaggattgg aacggttagt
    16981 agtaggaaaa acgattcaaa aagttcaggt cttgtggccc aagatcatcg agcaaccaga
    17041 gacacccatc tttgaggctt ctcttgttgg cgaaaccatc caatccattg gacgtagagg
    17101 gaagttttta atttttcatc tcgatcattg tgaactgatc tcacacttgc gaatggaagg
    17161 aaaatatcaa tttacgaaag aaaatacacc aatcgataaa catacgcatg tacttttctt
    17221 ttttgaggat ggaagccaac ttcgctacaa cgatgtacga aaatttggtc gtatgacaat
    17281 cgtcgaaaaa ggagcaagtg caacttaccg aggaatcatg aaattgggac ctgagccttt
    17341 gccagatagc ttcttattag cagatttcgc aaatggactg aaaaagtccc acaaagcaat
    17401 caagccattg ctgctagacc aacgtctagt gactggtcta ggtaatattt atgtagatga
    17461 agcattatgg gaagcgaaga tccatccaga acaaccggcg aacacactgc gccccaaaga
    17521 ggtagaacaa ttacgtctat cgatcattga tgttttggat cgtgcaatag aagccggagg
    17581 taccacgatt cgcagttatt tgaatgcatt aggagaatca ggcggatttc aagtagcact
    17641 gcatgtctat cagcaaactg gcaaaccatg tatacgttgt ggaacgccga tcgtgaaaac
    17701 aaaagtggca caaaggggga cgcactattg tccgaattgt caaaggctaa aaatcgcaaa
    17761 gtaggatttg ttttaggttt gacgggtgga atagctaccg gtaaaagtac ggcagccaaa
    17821 gtctttcagt ctcatggatt tcctttgatc gatggcgatg tgattgccag agaaactgtt
    17881 gagcctggaa cgcttgctct gaggaaaatt gtatcagtgt ttggccaaga ggtattgcag
    17941 cctgatgggc aactagatcg agggaaactt gggatgattg tttttccatc aaaggaaaaa
    18001 cggcaaaaac ttgatcagct attagatccg tttatccgaa aagcgataaa agatcaaatc
    18061 gcctctctaa gttccaatca tcctttagta attgtagata tcccattgct ctacgaaggt
    18121 cattatgacc actatatgga tgcagtagct gtcgtttata ctacgccaga aactcagctt
    18181 cagcgtttga tgaaacgtaa tcaactgacg ctagaacaag cgcagcagag aattagtagt
    18241 caacttccaa tcgaagaaaa aaagcagcgt gcggatattt tgttcgacaa caatggaaca
    18301 aaagaaatac ttgtgggaca aatcgaaaat tggctttttg ctaatcgctt tctttgagta
    18361 tctgtgtcaa ttttgctatc ctgagtatat agaaagtgag ggatagcgat gggatcatta
    18421 aaaaatcaaa aggataaagt cgtaggtaac gcaaaagaaa aaatcggcga gatgctcaat
    18481 aaagaaaatc taatcgatga aggtcgtacg caatcagaaa cagcagaaga aaaagaaaag
    18541 cagtaccaag caagaatcga tgaaatagaa gaccagcagg cagaagaaga agcgaagcgg
    18601 caagatttga ctcaagaacg aaaaaatccg acacctgatc gtagtaaaac accgctccca
    18661 gaaagtgacc acattcccga tgagcaaaaa atcgaggaac agcgaatgaa acactataca
    18721 ggaatcgaag agaagttata aaatagtaaa aaatcgagat gtgacttgaa gcagatgaga
    18781 aggtgttcat ctgcttcaag ttttttgtgc tagatgacta aatcagcttt tgtgtaagtt
    18841 atttctcagt aatcaaggtg atcagtattg gaaaattgaa atttagtaag gacaggggac
    18901 acaattacgc atgaaagtag aaaaaattgt tcttatatcc gtgttttttg ggtaggacag
    18961 tcgcgtttgt gatttgtttc gtgttataat acaactagtt gtaaagaaag acacatcctt
    19021 tatataaaat gcgatgcaag aggtgagaca aaatgagatg tcccagatgt caacataata
    19081 attcacgagt aatcgacagc cgtcaagcag atgatggacg tgcgatccgt cgccgtcgcg
    19141 aatgtgagaa ttgttcgttc cgattcacta catttgaacg aattgaagct gctccgttat
    19201 tagtaatcaa gaaaaacggg gaacgcgaag agttcaatcg cgataaaatt ttaagaggac
    19261 tcatccgttc agcagaaaaa agacctgtag ctatggaaca aatggaacaa atcgtcaacc
    19321 atgtcgaaaa ccgcgtacgc agtctcggag aaaacgaagt atcgacgaat ctaattggtg
    19381 aatatgtgat ggaagattta gttgatttag acgaaatcgc ttatattcgt tttgcaagtg
    19441 tttatcgcca gttcaaagat atgtctgttt tcttaaaaga gttgcaagat atcgtggata
    19501 aagcaaaaga aaataataaa gagaataata aagaaaacaa ttaagaaaca aaaaggaggc
    19561 atttccttgg aaaatgcttg gaaagagctt caaccaaaaa atatttacca aggaagaaaa
    19621 gcggctccgc tgagagaaga cagcaagaac gccttgctgt atctttatca gccactaatc
    19681 ggcggagaag ccttgagtat ctatttcacc ctgttatcag aaatctctca agaatctggc
    19741 aaaggtcctg aagggatgca tgcagatctg cttagtagtc taggctgcgg tatcccgcaa
    19801 ttttatgatg caagaaaaaa gctagaagga atcggcttac tggatgttta ttttaaagaa
    19861 gatagtgatc tgggacctcg ttttatttat gagctgttag aaccactcat tcctaaagca
    19921 tttttcaaag actctgttct ggcttttctt cttctggaaa aagttggtga acgacgattc
    19981 cagaagctta cccaattctt tgaacctaaa aggcatacag cagagggata tcaaaaaatc
    20041 acaaaaaaat ttttagatgt ttatcgcttc aatgaagcag tgtacgctgc taatcaagaa
    20101 aacatcgaat cgctgaataa atcttttgaa gaatctgaat cagtagcatt acttgaagca
    20161 gattcgacat tcgattggca gtttttgaat gattggctgg caaaaaaaca tattgcaagt
    20221 cttgatgatc caatcatcaa acaagtcgac atgtatcatc agctttacgg tttcgatgaa
    20281 ttgacacttg gcgaactgat cagtcaatct tatgacttta gtgaacaaaa agtatctgaa
    20341 aaagaactgc aaaaagccat tttggcaatg cagagacgtc cggtgaagca aacaaaagaa
    20401 acagttgcgg tttctgaaaa cagtaatgaa ccctcgtcaa acgaacattt gacaaacgca
    20461 gcgcttcagc tgataaaaga agcacagagc attccaccga tgaaatatct ggaagcaatc
    20521 aagtcagaaa aaggcggata tgtttctaaa caagaaaact ggttactgca agatcttgtt
    20581 tctcaatcag gtctttccag tagcgtgatc aatgttttgc tgaattatgt actagtgatc
    20641 aagaataatg ctagcttaaa tgccagttat gtaaatacag tggcaaatga atgggcacaa
    20701 aagaaaatcg ccacagcaga agaagcgatc cagcacattc ggcaaataag taatcaagca
    20761 aaacaatcaa aacaaaagaa gcaaacaaat tatcaaactg gcaagcgaaa tgttcgacgg
    20821 gaaaagcttc ctgattgggt caaccagcca aaagatgaaa aacagatcag cagcgagaaa
    20881 aaagcagaga ttgaccgccg ttttaaagaa tacctggcaa aaaaggaggg tgatatctag
    20941 tggaagacgt aggcaaagaa ttgaagagga tcatcagcaa acgcaattat caagaaaagt
    21001 atgctgaaat gatcgctgaa gtcttaaatg atgcggatgt tcaagctttt ctaagcgcac
    21061 accaagaaga attgacacaa gcggatattg aaaaaagtta cgctaaattg tatgaattcg
    21121 tgcaagaaaa gcgtaaatat caaaaaaacg atccaacgat gatcgctccc ggctatgagc
    21181 cgaagctgac gttgaatttt cattatgtgg atgtcactta tgtaccaacg gaagcattgt
    21241 tagcacggca aagacaagaa gaaatcagaa gccgagtaaa agcaatggat atgccaaaag
    21301 atattcaatc ggcttctttt gaaaactttg aacgtacaga tggacgagga tatgcgagct
    21361 tagaagccct agattttgta gagaaatata ctgctgatcc aaaagggtat cataaaggac
    21421 tgtatctagt aggaagtttt ggtattggaa aaacatattt attaggagca acagcgagag
    21481 aattagcgat tgctggattc accacgacgc tagtccattt tccgacattt gccgttgaga
    21541 tgaaacaggc aatcggaaaa gatcaagtgg cagaaaagtt agatgcagtg aaacgttcac
    21601 ctattttgat gatcgatgac attggtgcag atgcgatgag tagttggata cgagacgaag
    21661 tattcggtgt tatccttcaa tatcggatgc aggaacagtt accaaccttc ttctcatcga
    21721 attttacaat ggatgaattg gaacagcatt tgtccgtcac tcaacgtgga gatgaagagc
    21781 cgctaaaagc gaaacggata atggaacgca tacgttattt gacaaaagaa atcgaaatga
    21841 ctggtcgcaa ccgacgcaat ggttgaacag ttgacaagtc caactgacat ttgacctagt
    21901 agtaaaagca ggtcagcgaa tcattatatg gacagaaatg accggagaca atcaccgcaa
    21961 caagtaatgc agaaacttaa acggaggatt ttttatgagg gctatttttt ctagtatatc
    22021 tgtagttggt ctattttttc ttttagcagg ctgcggtagc gcagatagca acacaggttc
    22081 tgttgattcg attgatgcgg gtcaaacagt aaaaacaagc agtacgaaaa cggagagaca
    22141 aagcatattt gtcggaacga ttgaaagtat cactcaagta gaagcagaag aagaaacgct
    22201 tcagttgaaa ctcgtcgatg tcatggccaa agaagatcca gcgaatatgg gaacgtcatt
    22261 cagcaatgac ggagtgatct taaatgctac tgctgaaaaa ataagcgtgg acataaatga
    22321 attgaaaatc ggtgacaaag tccaatttac attagttgag atgccgatca tgacgatgtc
    22381 tatcccaccg caagttcctg gagattcgat tattgatgtt tcattgaaca aataaccaat
    22441 aacatttttt caaaaataag aaaatgttgt tttatagaac gaaaaggtat attttttaag
    22501 gagatatggg aattttttta ttcctagtct ccttatttta tttggaaaat gctataatta
    22561 tctagaagga gtgaagctat gaaccattta gatttatctc agcgcttagc cgcagtgggt
    22621 gactttgtcc ctgaatccgc tcgtttagca gacattggat cagatcacgc ttacttaccc
    22681 gttgcattga tattaagagg aaaaatcgaa tatgcagttg ctggtgaagt cgttcaaggt
    22741 ccttatgaat cagcacgtaa gcaagtcaaa aaagatggat tagaagaccg tatcaccgta
    22801 cgccttgcaa atggtctaga tgctatccag ccacaagatg gtattacagc tgtcacgatt
    22861 gcgggtatgg gaggttcact gatccgagat atcctagaag ctggcaagtt gaatcaacgc
    22921 ttaagcggac aagaacgttt gatccttcag ccaaacatcg gagagcgtac attacgatct
    22981 tggctgcaag aaaatcagta taaaatccaa tcagaaaaaa tacttgaaga aaataaaaaa
    23041 atatatgaaa tcattgtagc cgaaaaagaa caaaaaccag ttacttacaa tgaaatggag
    23101 ctgatgttcg ggccatttct gcttgaagag aaaagtgaga tcttcaaatc aaaatggaca
    23161 agagagcttc aacaaagaaa agctatccgt gaacagctca aacaagcagc taatcaagag
    23221 gcacgtcaaa aacaaatcga gcaggaaatc caaatgattg aggaggtttt aaagccatga
    23281 caatcagcgg acgcactttc atccaaaagt ttgaaagcta ttgtcctcag tggctagctg
    23341 aagaaggaga cccagtcgga ctgcatatcg gaacattgga taagccaatc caacgagtaa
    23401 tgatgacatt agacgttcgt ccagaagtgg tcgaagaagc aatcaagaaa aaaatcgatt
    23461 tgctgattgc taaacatcct ccaatctttc gtcctgtaaa acggctggtt actgatcagc
    23521 cacaagaaaa aatgtatgca gatttgttga aacatgatat tgccgtctat gcagcacaca
    23581 cgaacatgga tattatttgg gatggactga atgactggtt ttgtgaactt ctcggtattg
    23641 aagtggagag ttatttagta aagactcatg agattcatta taaaaaactg gccgtttatg
    23701 tacctgtgga tcatgcacag aaaatgcgtg aagtattagc tgcagctggt gctggtacac
    23761 aaggtgatta taccggtaca agttttacct cgattggaca cggtcgattt actccggaag
    23821 ctggtgcaca accagcgatt gggaaagtag ggaagacaga acaagttcaa gaggcaaaag
    23881 ttgaggttat tttgccggaa actatcgaaa aacaagtgat tcaagccatg cggtcagctc
    23941 atccttatga ggaacctgct tatgatcttt tcgctataga tgaaccagtc gaaatgtttg
    24001 ggttaggacg agtaggtgaa ttgccgcaag aaatttctat agaggcattt gtagaacaag
    24061 taaaagaagc gttccaacta gatggactga gaatagtcca gccaaaaaat gcaaaatcct
    24121 ctgtgaagcg cattgcgatt tgcggtggaa gcggtgaaaa attttatccg caagcaatcg
    24181 cccaaagagc agatgtctat atcacgggag atatctatta tcatacggct catgatatgc
    24241 aaagcgctgg gttgattgca attgatcccg gtcattatat tgaatcgtta tgcaagcaac
    24301 gatttatcga gaaatttgaa tcttggaaac aagaagaaaa ttgggatatt aactttttcg
    24361 tttctgaaac aaatacaaac ccatttcaat ttaattaaaa ggagagaata ctatgtacga
    24421 aaatcttttg ccacgttttt tacgatatgt caaaacagaa acacgctccg atgcaacaag
    24481 caaaacgact ccatcgactc agacacaagt tgcttttgcg caagaattga aaaaagaatt
    24541 agaagagtta ggcttagctg atgttttcta taatgaagat aacggattcg ttatgggaac
    24601 attaccaagc aatgttgatc atgaagtgcg ttccattgga tttatttccc acatggatac
    24661 agcagatttt aatgcagtag gagtcaatcc acaaatcatt gaaaactatg atggcgagtc
    24721 tacgatcgta ctagatgcgg aagaacgcta tacattgaat acaaaagatt ttccaaattt
    24781 gaaaaattat gaaggccaca cattgatcac aacagatggc agtacattac tgggagcaga
    24841 tgacaaatca gggattgcgg aaatcatgac tgcaatggag atcttgatca ataatccttc
    24901 tatccctcac ggtaccatca aagtggcttt tggtcctgat gaagaaatcg gtgtcggagc
    24961 ggataaattc gatgttgagc aattcgatgt agattttgct tatacagtcg atggtggtcc
    25021 tttaggtgag ttgcagtatg aaacgtttag tgctgctcaa gcaaatatta cgatccaagg
    25081 gaaaaatgta catccaggga cggcaaaaga tacaatgatc aatgctctac agttagcaat
    25141 cgattttcat aatcagcttc cagccgatga agttccagaa aaaacggaag gatacgaagg
    25201 tttcttccat ttgatggcat tggatgggaa tcctgaagaa gcttctatga gttatatcat
    25261 tcgcgatcat gatcgtgaaa aattcgaagc acgcaaagca caaatcacac atatccaaga
    25321 agagttgaat cagcgatttg atcaagaacg aatcaaagta gatatgtatg atcaatatta
    25381 caacatgaaa gaaatcattg aaaaagatat gagcatcgtg gaattagcga aacaagcaat
    25441 gatcgagctt ggtatctctc cagtgatcga accagttcgt ggaggaacag atggttcaaa
    25501 aatctcttac atgggtattc cgacgccaaa tctatttgcc ggaggagaaa atatgcacgg
    25561 acgattcgaa tttgtttctt tacaagtaat ggaaaaagca acagacgtga ttgtaaaaat
    25621 tgcagaattg aacacaaaga gttaaaatcg aaaaagaaca gcttatgaca aggcgttcgt
    25681 cccaatgatg gaatgtcatc tgtctaaggc taaagggcag gacaatggaa ttggttgtcc
    25741 cgccctcttt tttgaagagt aaataggagg taaagaatgg aaaagctgct agttttttat
    25801 aacaaaagtt cagggaaaga tgagggtgag aaattagcac gctggtttca agattatgta
    25861 aaagaaaagc agccagaatt atatgtagaa ctagctgaaa ctggcccatc gattgatgat
    25921 gcggaattag tcaagaaagc agaagccata gaagctgata ctttagtaat tataggtgga
    25981 gacggcacga ttcatcatat cgtccaagcg ttccaaaaaa cattatctca ataccatgtc
    26041 ggattacttc caggtggaac tgtcaacaac cttgcacgtg ttcttgagat tcccctcaaa
    26101 aaagaagaag ctgctgacgt gatcctggaa ggcaatgtac ggaaaataga ctatggtcaa
    26161 gtcaatgatg aagtcattat ctctacactg acaatcggaa tcttagcaga tacagcagtt
    26221 tggatcagtc aagaagaaaa acagcgttac ggctcgtgga tctttatcaa gaagtttttt
    26281 aagttattgc tgaagaagaa aaaatatcat ttggatttag aaacagacga ggagcattgg
    26341 aaaggaaaat cccaactgtt gacagtcacg atgtctaact ccgtgggcgg ttttacaaat
    26401 tttgacgact cagcgaccct agatgatgga aaatttcatg taacgatcgt accttcctta
    26461 gatattttcc gatttatttt ttatttgcct agaatcatga gaggcaaatt ctatacgatc
    26521 cccggcatta cttatttcac agccaaacgc atgaaaatcc aagcgcagga aaaatctgtg
    26581 ggcactcgaa cggatggaga cacgacagat gatcttccag ttgaattatc tgttgtatca
    26641 aaaggattaa cagtttattc accaaagaaa gaagaaaaag cttagaaata gtagttaaca
    26701 gaaagttgga agaagagtaa tggatgtatt gttacacaat cctttgtggt tttacctttt
    26761 cattgtgaat ttttacttat tttgtctgat ggggtatgat aaacatcagg ctagaactag
    26821 cggctggcgt gttcctgaga ataatttgat atttgtcagc ctgttaggcg gtggtttggg
    26881 aggattgatc tctcgaaaag ttttccatca taaaactcgg aaaaagaagt ttactatagg
    26941 attcgctgca ggtgtacttg ttgatttgat tctcatttat tttttccatt aaggagcagg
    27001 agatgtcgtc taaaggaacg aaaactaaaa tcattctgaa tctgcttttg ctgattgtga
    27061 tttttgccat tatttattat ttaatcaatc aatcatttgc agatatcttt gccgaattgc
    27121 tgtctaccag tgttgttgtt ttggcagcgg ctgttatatt agggacagtt taccaaatcg
    27181 ctgaagggcg ctcaatcaaa gaaattgctg aacctttcgc gccgaatttt acaacgaaag
    27241 atgggttctt gacctctagc tatattgcgt tttaccgaat cgtttcgttt ggtacaggaa
    27301 cgctgatctc ggagatttat ttttataaca aaaaaggaat gaagctatcc cagggagcag
    27361 gggtgacagc actccatatg attatgtaca aactggcagt gatcacttat gcattagctg
    27421 gcttggtcat ccaattctct cttttttatt ctaatggtcc atcaatgatc tggtttatca
    27481 tcgctggtat ccttttgacg atcgtgattg ttgccttttt attggcgatg tccgtcagct
    27541 tgaatgttca aatatttttt gtcagcttat cgaataagtt atttaaaagt gagcgtttgc
    27601 ggaaatgggt ggatacatgc aatcagcaga tctactcttt aagggaaacg gtccaaacca
    27661 ttatccaaga caggactgcg ctattgcgga tttatctatg gaatatgtta aaacttgtat
    27721 tttggtatgt acttccttat ttgattctga ttgaaaacca tcctaaaata gattttctac
    27781 tgaccatttc gtttatcagc tttgcagtag tgctttcagg ggttattcct acgcctgctg
    27841 gtattggttc ctttgaattt gtctatttgt tattattcag accagttgtt ggaacagttg
    27901 acgcagtttc ttcgctttta ctgtatcgtt tcagttcctt tatcttgcca tttctctatg
    27961 gatttgtgta tgtgattgct gaacggcgaa gagtgatcaa agaagaaata atagaagtaa
    28021 aaaaagagaa taaagaaaat caagggtagg tcttttataa gatctaccct ttttatcaaa
    28081 tcaaagaaaa acgttatgga taagataatt ttacgtttgt ttggctcttt ttttatatac
    28141 atacaatcaa ttttgttttt ttaagattta tataagtcga gaaaaaaagt caaaaaacta
    28201 tgtgtatatt ttgaccaaaa ttgaccaaag cgatataata gtttttgtaa agatcaaaga
    28261 aataagtgat cttaccttta attaggaggg tatacctgta tgaatattga gaaaatgact
    28321 acgacgcttc aagaagcgat tgctgaagct caacagattg cggtcactcg aaaacatcaa
    28381 gatatcgaca ttgcccatgt atggaaaatc tttttacaat ctaatcattt tggtcgaaat
    28441 ttctatacgg atgccggatt ggatgtcgaa tcttttgaac atgaaattga tcgtctactg
    28501 gatgagtatc cagttgtttc tggtggaaac gtccaatatg gacaaaacct cagccagaat
    28561 ttctttcgat tattgaatga agcagaccaa atacgtgaaa gcttcggcga cgagtttctt
    28621 tcaacggaag tcgttatttt agcgttgatg aaattaaaaa attatccgtt aactgtttat
    28681 ttgaataaaa acggattatc tgaaaaagaa ttgcgtaaaa acatcgaaga gatgagagga
    28741 ggagaaagag tgacctcaca aaaccaagaa gaacaataca aagcattaga aaaatacggc
    28801 gttgatttag tacagcaagt caaaagcgga aaaatggatc caatcatcgg tcgtgatgaa
    28861 gaaatccgtg atgtcatccg tattctttca cgaaaaacaa aaaataatcc tgttctgata
    28921 ggagaacccg gtgtagggaa aacggcaatc gttgaagggc ttgctcaacg tatcgtacgc
    28981 aaagatgtgc ctgaaaattt aaaagataaa acgatttttt cattagatat gggtgcattg
    29041 atcgctggag caaaattccg tggtgaattt gaagaaagac taaaagcagt cttgaaagaa
    29101 gtcaaaaaaa gtgatggacg tatcctcttg ttcatcgatg aaatccacaa tatcgtaggg
    29161 gcaggaaaaa cagaaggaag tatggatgcc ggaaatctgt tgaaaccaat gcttgctcgc
    29221 ggtgaattac atttgatcgg tgccacaact ttagatgagt accgtcaata tatggaaaaa
    29281 gacaaagcgt tggaacgtcg ctttcaaaag gtattagtca aagaaccaac agtggaagat
    29341 acgatcagta ttctgcgtgg attaaaagaa cgttttgaga tccaccatgg tgttaacatc
    29401 catgacaacg cattagtagc agcagctact ttatctgacc gttatattac tgatcggttc
    29461 ttaccggaca aagcaatcga tttgatcgat gaagccagtg caacgattcg ggtagaaatg
    29521 aactctatgc caacggaatt agatcaagtt actagacgtt tgatgcagtt ggaaatcgaa
    29581 gaagctgcac tgaaaaaaga atcagatgat gcaagtaaaa aacgcttgaa aaatttgcaa
    29641 gaagaattag ctgaacttcg tgaagaagca aatgcgatga agatgcagtg ggaaacagaa
    29701 aaagaagaag tcaattctgt ttcagcaaaa cgtgctgaaa tcgataaagc aaaacacgaa
    29761 ttagaagatg cagaaaataa ctatgattta gaacgcgctg ctgtattgcg tcatggtacg
    29821 atacctcaat tagaaaaaga attgaaggaa ttagaagcta aagcaaaaga cagcgagatt
    29881 aagatggttc aagagtccgt taccgaaaat gagattgctc aagtcgttgg cagattaacg
    29941 ggtatccccg taacgaaact tgtagaaggt gaacgagaaa aactaattaa attgaatgaa
    30001 acacttcata aacgagtgat tggtcaagat gaagcagttg atgcggtcag tgacgcggta
    30061 attcgttcac gggctggatt gcaagaccca aatcgtcctc taggttcttt ccttttccta
    30121 ggaccaactg gtgtcggaaa aaccgaatta gcgaaagcgt tagctgagaa cttgtttgac
    30181 tcagaagatc atatggtacg gatcgatatg agtgaatata tggaaaaaca tgctgtgtct
    30241 cgtctagtcg gagctcctcc aggctatgta ggttacgaag aaggtggtca attaacggaa
    30301 gctgtcagac gaaatcctta tacaatcgtc ttgttggatg aaatcgaaaa agcgcatccc
    30361 gatgtcttca atatcttgtt acaagtccta gatgacggac gcttgactga ttcaaaaggg
    30421 cgagtagtag atttcaaaaa tacggttctg atcatgacca gcaatatcgg ttcacagtta
    30481 ctgctggaag gcgtgactgc tgatggaacg attccagaag cagtggctga acaagtcaac
    30541 acgctattac gtggaaactt caaaccagaa ttcttgaacc gaatcgacga cacgatttta
    30601 tttacaccat tgagcctaga caacgtgaaa ggaatcgttg acaaaatggt ggcgcaattg
    30661 gcacaacgtc tggaacatca agaaatcctg ctgacaatca gtgatgaagc caaaacgtgg
    30721 attgctgaaa atgcttatga accagcatat ggtgcaagac cattgaaacg atttatcact
    30781 aaggaagtag aaacaccact agctaaagaa atcgttgcag gacatgttat gcctaaatca
    30841 aaagtaacga ttactttact tgatggacaa cttcatttca aaacagaaga gctagaagaa
    30901 atcgtctaat cttccattga gactataaaa gaaaaaaggg gtctgacaca actagtgtca
    30961 gacctccttt tttcaaataa acagtgttcc agaagtagtt tcttcgaaaa ataagccgaa
    31021 atttcttgaa gctgcccgct tctgtcacaa cctcttttat taggtatttt tcactttttc
    31081 taatttataa ctttcaaagt aacgctcatc ttttttactt tgagaccatg caaacaatcc
    31141 cattaaggca gcacctatcg tatttgtcag caagtcgccc atcgtatcca tcaatgctgc
    31201 tcgtccgaca aacagtgtgc catcagaagc agcaaaacgt tgaagattca tgcctaagaa
    31261 ctggtcgcat aagaattccc agaactccca aaacacgccg caaagtccag caaacgcaaa
    31321 gccgaataag aggaacaacc aaggactggt ttttgatatc tcagcatctt tcatcaagta
    31381 accaatcaat ccatagccaa gagctgtcag gaccattgga ctcaccgcat gtaagatttt
    31441 gtcccaaaaa gagatgatac tgatcaaatg catccctgtg cctaaaaaga cagagatgaa
    31501 caagaaaaac cagtaaaaca aaacgattgc tgctggtatt ttaagtttga aaactttcaa
    31561 aatgacttgt ggcatgaaaa tcaatgcaat ccctaataaa gattccacga taaatgtgat
    31621 tccttgagaa gtcgaatatt tttgtgtgat aaattcataa aaattatagc agacaacgaa
    31681 tacaccaaaa gcaagtaaag ctatttgcac ctttttgatt tctttaatca ctgaaagtcc
    31741 ctccatctaa aaatcttttt acttctgaaa gcaactcaat ttctgaagaa accacttttc
    31801 cgttcaattt gatcaaacct attgtatata agttcaggta gtgaaattga ttttcagctg
    31861 tttcttgtag tgcagcgatt tttttcgggt gggttccgcc ttgctgtcga gtatcagtat
    31921 ataagccgat cactgggatg cctttcgcat aagccacacc gatttccgat gctaccccgg
    31981 catcgatcgt cagcccatct agtaaagcaa tcattaaatc actagccaac actttttctg
    32041 tgtcagcaag agcaatcatt cgactgtctg cataagcagt tttgtcattg attgcttcat
    32101 tttcttgagg aagatagatc gaaagctcag aagagagctc tctgatttct ttaactaact
    32161 gttggttata taacaaatca cttttagcaa acattggtgc ggcaaaataa attttcatct
    32221 aaacatcatc ctttttatca aaaataatcg ctaaagtaag cttccatgtt tggaatgata
    32281 cgctctagtg acttcagtgt ttcttcatct gtttctaacc gttcgattct tgccaaataa
    32341 gaagcacggc gataattcat catcaagcaa gtcaatgttt ggatatccag tcgaacggat
    32401 tttcctatag gttcatttaa gacacggact tgtccctgtt catcccatgt taaagcgaag
    32461 acaccattat tccaaggagc gacaggatct tcaatgatga aatgaaaagc atcagctgtt
    32521 ccaacaaacg gaaaccgttg aaggaattct tttacatcaa cgatccgagc cataaaatat
    32581 ggttcgatct gctctttgat ctgactatct tcaatcaaaa atgctaaagg ctcattttta
    32641 taaatatctc catgtaccca gtagatcatg gaaaaatgtg cggaaataaa gttccataag
    32701 ccatttcgag cttcttgatc aagatagaac atttctttta cgtgaaatat ttcttcagct
    32761 acccagtaga acagaacacc tcttggttca tggttgctat cgtagtagac agcggctgtg
    32821 cgctcatctt cattttcgaa acgccaatac tcttcccaat gaaaatcact gcggaataaa
    32881 gcaccatggt tttgttgggc aaatttgtca taaacggaaa atacgtctgg atgatcaact
    32941 ggtaatcgct caaccatacc acttactggg atttgtttag gtagctgtgt atctctgatt
    33001 ttaaaggaaa gtttatcaga catgatttcc catcctttac gccgatagta ggggatactg
    33061 taaggataca aataagagat ccattgctta ttcttgcgca tattatccaa tgcaacgata
    33121 attagatctt gcatcaatcc atggttagca tattctggat aagttccaac tccagtcaca
    33181 ccacccattt tataacgtgc accgtgaata ttgacttcac aaggatagat agcgatttga
    33241 gagatcagtt tattttcgtg gaaccatccg aacactttcg atacttccaa aatcggtttt
    33301 ttggaacgga taaaagctcg tttattctca aacccgcttt cctcgatgtc tgcttcagtc
    33361 acttggaaca cataggaaag caattcattg aattgatcga tatgttcttg agtgaccggt
    33421 tttaattcaa gattttctct aaaatctttt tgatccattt tttcatctcc atttattagc
    33481 ttgataacag tatagcaaaa ttctacaaaa aaaacttcta tagctgacta attaaaaact
    33541 ctttaaatta ctgcttttcg ttggtataat ggaaagtgct gattatatga aaagaggaga
    33601 cgctatggat ataaagaaaa tgaaagaacg ccaagagcag attcgtaatt tttcgatcat
    33661 cgctcatatc gaccatggga aatctacatt ggccgatcgt attttagaaa tgacgcacac
    33721 tgtgacgtct cgcgaaatgc aagatcagct gttagactcg atggatttgg aacgtgaacg
    33781 tggaatcacg attaaattaa atgctgtaga actcaattac acagcgaaaa atggagaaac
    33841 atatatcttt cacttgattg acaccccagg gcacgtcgac ttcacctatg aagtctctcg
    33901 aagccttgct gcctgtgagg gtgccgtttt agtggtcgat gcagcacaag gaatcgaagc
    33961 acaaacattg gccaatgttt atttagcgtt agacaatgat ttggagatcc tgccagtcat
    34021 caataaaatc gacctacccg cagcagatcc cgaacgtgtc cgtcaagaaa tcgaagacgt
    34081 aatcggaatc gatgctagtg aagctgtatt agccagtgcc aaatcaggga ttgggattga
    34141 agatattctc gagcagatcg tggaatatgt tcctgcacca agtggagact tagatgcacc
    34201 gctaaaagct ttgatctttg actctattta tgatagttac cgcggtgttg ttctaaatgt
    34261 ccggatcacg gacggtatgg tcaaacccgg agacaaaatc aaactgatga gtaatggcaa
    34321 aacatttgat gttacagagg tcggggtctt ctcgccaaaa gcagttgcta gagacttttt
    34381 gatggtcggt gatgtcggtt atatcacagc aagtatcaaa actgtccaag atacacgagt
    34441 aggggataca gtaacgttag cagacaatcc tgccgctgaa gctttaccag gttaccgaaa
    34501 aatgaatccg atggtttatt gtggtcttta tccaattgat acttctcgtt acaacgattt
    34561 gcgggaagct ttagaaaaac tgcaattgaa tgatgctgct ttacaattcg aaccagaaac
    34621 ctctcaagca ttaggttttg ggttccgctg tggattcctc ggacttcttc atatggatgt
    34681 cgtccaagaa cgcttggaac gggaattcaa tctagaattg atcacgactg caccatccgt
    34741 tatttaccat gttaataaaa cggatggtac gactgctaca gtagataacc cggcagattt
    34801 tcctgaacct gtaacgattc aggatgtaga agaaccattc gtcaaagcac agatcatggt
    34861 cccaaatgat tttgtcggtg cagtaatgga actttctcaa cgaaaacggg gagaattcat
    34921 tacgatggat tatttagatg attaccgagt aaatgtcgtc tataatattc cgctttctga
    34981 aattgtcttt gactttttcg acaaattgaa atcaagcacg aaaggctatg cctcattgga
    35041 ttatgaaatg tctggttatc aaaaaagcaa gttagtgaag atggacatct tgctgaatgg
    35101 agaaaaagtc gatgcattaa gctttatcgt tcaccgagac tttgcctatg aacgtggaaa
    35161 agcaatcgtt gaaaaactga aaaaactaat cccacgccaa caatttgagg tgccaatcca
    35221 agcagctatt ggacaaaaaa tcgttgcccg ttcagacatc aaagccttgc gtaaaaacgt
    35281 cttggctaaa tgttatggtg gagatgtttc tcgtaaacgt aaactcttag agaaacaaaa
    35341 agaagggaag aagcggatga aacaaatcgg ctccgtcgaa gttccgcaag aagccttcat
    35401 ggccgttctg aaaatggacg aggacgaacc gaagaaatag caagggtttg tttgaaaaca
    35461 gtgtaaaaaa taaaccatgt ttacatggat ttgccaccgg tttgccaccg gtggtttttt
    35521 tcggtggcaa aaatcaagaa ttctttctaa gattttccat gatatcgacc gtttcatttc
    35581 tcatcttatc tgttacatgc gagtaagtat ccatcgtaat tgaaattctg ctgtggccca
    35641 atcgttcaga gatttctttc atttttgcgc cattttcgag aagaagtgta gcatgagtat
    35701 gtctgagaga atggaagtta aaagagaggg agagtgcatt cgatatcctc ctagtattcc
    35761 atttcactac acttggcgta actagctcac cgtcttcctt cgtacatact gcatttgaat
    35821 caatgtagag ctttccatac ttcattcgat tttctaattg ttgtttctta tgttttttca
    35881 gaattgctag caaggtttgt ccaataaaaa tcgttcgatt ggaactgctt gtctttggcg
    35941 taccatatac ccatgcgccg tcattcttta ccatttgttt ctctacagta attgttccat
    36001 ttgaaaaatc gacatcatcc cacgtcagac cacaaacttc gccaacgcgc attcccgtat
    36061 aaaatccaat attcaaagga atatagaaag gatgtccttc aggagtaatt tctagcatat
    36121 gatcaaagtc ctcaagagaa atgattttta gatctttttt agtcgttggt cgtgcttcat
    36181 attttggtat ttttacatac agcataggat tttgcttgat taatccccaa ggataaaccg
    36241 ccatattcag cgcattctta aggacagagt gagtaatagt cattgttttc ttcgagtaac
    36301 cctttttaaa ttcagcattg atgaaatttt gtaaaagagc aggggagaga tccgtaagtt
    36361 ttttctttcc taaataaccg tttatatgat ttttgatggt aaatcggtag ttttcatagg
    36421 tattgtattt tagatttagt ttaacgtatt cctccatcca aaaatcaagg tattgtttta
    36481 ctcgagtatc cgtacctaaa aagtattgtc ctgtttcgtc aatatctgat aaaacttttc
    36541 gtaaagcagc ttcggcctct ggtcgggtgt ctccgccaac tttctccact ttttttcttg
    36601 agccatcatc attgatatct
//
LOCUS       DAPBCF010000024        33038 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.024, whole genome shotgun sequence.
ACCESSION   DAPBCF010000024 DAPBCF010000000
VERSION     DAPBCF010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33038
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.024"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(43..2493)
                     /gene="parC"
                     /locus_tag="RD508_001482"
     CDS             complement(43..2493)
                     /gene="parC"
                     /locus_tag="RD508_001482"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HDT7736091.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     VTIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(2505..4550)
                     /gene="parE"
                     /locus_tag="RD508_001483"
     CDS             complement(2505..4550)
                     /gene="parE"
                     /locus_tag="RD508_001483"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HDT7736092.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLTVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEVPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(4716..5150)
                     /locus_tag="RD508_001484"
     CDS             complement(4716..5150)
                     /locus_tag="RD508_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDT7736093.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEVADDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            5277..5915
                     /gene="plsY"
                     /locus_tag="RD508_001485"
     CDS             5277..5915
                     /gene="plsY"
                     /locus_tag="RD508_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDT7736094.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(6047..6922)
                     /locus_tag="RD508_001486"
     CDS             complement(6047..6922)
                     /locus_tag="RD508_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDT7736095.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNREIFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADAVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(7004..7795)
                     /gene="codY"
                     /locus_tag="RD508_001487"
     CDS             complement(7004..7795)
                     /gene="codY"
                     /locus_tag="RD508_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HDT7736096.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(7813..9213)
                     /gene="hslU"
                     /locus_tag="RD508_001488"
     CDS             complement(7813..9213)
                     /gene="hslU"
                     /locus_tag="RD508_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HDT7736097.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALIKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(9227..9775)
                     /gene="hslV"
                     /locus_tag="RD508_001489"
     CDS             complement(9227..9775)
                     /gene="hslV"
                     /locus_tag="RD508_001489"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HDT7736098.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(9812..10717)
                     /gene="xerC"
                     /locus_tag="RD508_001490"
     CDS             complement(9812..10717)
                     /gene="xerC"
                     /locus_tag="RD508_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HDT7736099.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(10915..12291)
                     /gene="trmFO"
                     /locus_tag="RD508_001491"
     CDS             complement(10915..12291)
                     /gene="trmFO"
                     /locus_tag="RD508_001491"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HDT7736100.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLDSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(12260..14338)
                     /gene="topA"
                     /locus_tag="RD508_001492"
     CDS             complement(12260..14338)
                     /gene="topA"
                     /locus_tag="RD508_001492"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDT7736101.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVIARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDIVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(14460..15317)
                     /gene="dprA"
                     /locus_tag="RD508_001493"
     CDS             complement(14460..15317)
                     /gene="dprA"
                     /locus_tag="RD508_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDT7736102.1"
                     /translation="MYQIEENLLKLAYAKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITTHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVVEAGYVIVSGCAKGIDTYGQQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHRFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(15373..16140)
                     /locus_tag="RD508_001494"
     CDS             complement(15373..16140)
                     /locus_tag="RD508_001494"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDT7736103.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(16133..16993)
                     /gene="ylqF"
                     /locus_tag="RD508_001495"
     CDS             complement(16133..16993)
                     /gene="ylqF"
                     /locus_tag="RD508_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HDT7736104.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            17254..17652
                     /locus_tag="RD508_001496"
     CDS             17254..17652
                     /locus_tag="RD508_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7736105.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWVMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            17931..18431
                     /locus_tag="RD508_001497"
     CDS             17931..18431
                     /locus_tag="RD508_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HDT7736106.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRVIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(18514..19065)
                     /gene="lepB"
                     /locus_tag="RD508_001498"
     CDS             complement(18514..19065)
                     /gene="lepB"
                     /locus_tag="RD508_001498"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDT7736107.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(19217..19444)
                     /locus_tag="RD508_001499"
     CDS             complement(19217..19444)
                     /locus_tag="RD508_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HDT7736108.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(19441..19959)
                     /gene="msrA"
                     /locus_tag="RD508_001500"
     CDS             complement(19441..19959)
                     /gene="msrA"
                     /locus_tag="RD508_001500"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDT7736109.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(19979..20692)
                     /locus_tag="RD508_001501"
     CDS             complement(19979..20692)
                     /locus_tag="RD508_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HDT7736110.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(20695..21591)
                     /locus_tag="RD508_001502"
     CDS             complement(20695..21591)
                     /locus_tag="RD508_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDT7736111.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(21749..22591)
                     /locus_tag="RD508_001503"
     CDS             complement(21749..22591)
                     /locus_tag="RD508_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7736112.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEEILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            22723..23376
                     /locus_tag="RD508_001504"
     CDS             22723..23376
                     /locus_tag="RD508_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDT7736113.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(23440..23967)
                     /locus_tag="RD508_001505"
     CDS             complement(23440..23967)
                     /locus_tag="RD508_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDT7736114.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEIDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(23987..24934)
                     /locus_tag="RD508_001506"
     CDS             complement(23987..24934)
                     /locus_tag="RD508_001506"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDT7736115.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKEVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(24946..26832)
                     /locus_tag="RD508_001507"
     CDS             complement(24946..26832)
                     /locus_tag="RD508_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7736116.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSGDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(26997..29069)
                     /locus_tag="RD508_001508"
     CDS             complement(26997..29069)
                     /locus_tag="RD508_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDT7736117.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRHADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKRVQ"
     gene            complement(29082..29357)
                     /locus_tag="RD508_001509"
     CDS             complement(29082..29357)
                     /locus_tag="RD508_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736118.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(29719..30174)
                     /locus_tag="RD508_001510"
     CDS             complement(29719..30174)
                     /locus_tag="RD508_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736119.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(30328..31536)
                     /locus_tag="RD508_001511"
     CDS             complement(30328..31536)
                     /locus_tag="RD508_001511"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HDT7736120.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPSLKEEGEALLRFAELPSVPLKEESQVWTLLISQLGLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(31648..31980)
                     /locus_tag="RD508_001512"
     CDS             complement(31648..31980)
                     /locus_tag="RD508_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HDT7736121.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            32128..33003
                     /locus_tag="RD508_001513"
     CDS             32128..33003
                     /locus_tag="RD508_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7736122.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
BASE COUNT         8828 a         7025 c         5714 g        11471 t
ORIGIN      
        1 tattaataca gatggcgtct cttcattaaa atactacaac agttacgact cgatgaaaat
       61 ctcaggagca tcgataactt cgatgacttc tccacctttt ttctcatcca tcgcaaatga
      121 tccattcgat gttcgatcac ctatagggaa atcagttggg tcaatcgtta actgctgccc
      181 tttttgattc atcaaggtta tttcttttga tcttccttcc gacatataga taatacggtg
      241 cggatttttt ttcagctcac gcatgaccgt cactccccgc ttcgcacgtg aagtttggct
      301 gatttcttga gcaagcatgc gtttaacagc tcctcgctga gtaacgatta cgatcggcgt
      361 atcaccttct gctaacacaa gcagcccgtt gataatccta tctccatctt tcaaattcat
      421 agacttcact ccagctgcct ttgctccaac aacgggaaca tctgttaaag gatagcgcaa
      481 acccattcct tgatgcgtta ctaagaaaac atctaagcct ggctgatctt ctttcagata
      541 cacagcaatc agttcatctt cttccgcctt tagcttcata cagctgagcg gacggctctt
      601 ataggtgcgc catggttcga actctgtcat tcgtgtttgc ttgatcaatc cattcttgct
      661 gatgaataca aatgttttct ctgcttgaat tttttgatat gggaaaacag ctaaaatcga
      721 ttcgtctaca gacagattgg agattgtttg agaaatgtgc tcaccagcat ctttccattt
      781 caaatcgggt agttcatgga cagggcggta gatcacattt gctttatttg tgatcagaag
      841 aacatggtcc aatgtactca attcacctga gtatagcaag tagtcgcctt ctcgcatccc
      901 gatttcttct ggtttggaag cactataaga acgaaggctt gttcgcttca catagccttc
      961 tcgcgtcaca ctgacaatta cgtcttcttg tgccactaag acttgcgtat caattttgat
     1021 ttcttcgatt tcgtcttcga ttgtcgttag acgagcggaa gaataatttt ttttcacttc
     1081 tcgcaattct tttttcataa cagagaaaag ctctttgtca tttgaaagga ttttattcaa
     1141 ctctgtgatt tgcgcaatca agctttcgga ttccttttga agctctgtga tatccgtgtt
     1201 cgtcaaacgg tataattgca atgtgacaat tgcttctgct tgttcttctg taaattgaaa
     1261 gacgtcgact aaattctttt tggcgtcttt tttgtcttta ctttcacgaa tcgttacgat
     1321 tacttcatcc agaatcgata aagctttcat caatccttct acgatatgct gtcttttttg
     1381 agctttggct aaatcgaatt gactacgttt tgttatgact tgctttcgat gctcgatata
     1441 acttcttaaa atgtctttca gtccaacttg atgcggagtc atatggtcga tagcgaccat
     1501 attgaaattg taattgatct gtagctcagt gtttttgaac aaataattca aaattccttg
     1561 agcattggcg tcttttttca attcgacgac aatttgcaga cctgttctat cactttcatc
     1621 tcgtacttca gctattccat cgattttctt attcaaacgg atctcatcca tttttttcac
     1681 caaggtcgct ttatttactt catatgggat ttctgtgatc acgatttgct gtttattacc
     1741 cttcattgcc tctatctttg ttttcgaacg aagaataact tttcctcgcc ctgtttcata
     1801 agcttttttg atttcatctt ttccttgcaa gatccctcct gttggaaagt caggtccagg
     1861 aatatattcc atcaattttt caaggctcgc ttgtggatga tcgatcatat agattgtgcc
     1921 atcaatcact tcagctaagt tatgagtcgg gatttctgtt gcatatccag cagatatacc
     1981 tgtcgatcca ttgacgagaa ggtttgggta tcgagctgga aggactgttg gttctttttc
     2041 tgtatcatca aaattccaca cgagatcgac tgtttctttt tcgatatctg ctagcatctc
     2101 tccacttaac ttggataatc tggcttcagt ataacgcatc gcagcaggtg gatcaccgtc
     2161 catactcccg ttattcccgt gcatttcgat cagtacttcc cgcaacttcc agtcttggct
     2221 catgcggacc atcgcttcat aaatactgat gtcaccatga ggatgataat tccccatgat
     2281 atttccgaca gattttgctg atttacggaa tcctttgtca tacgtattgc catctttgtt
     2341 catggcaaat aatatccggc gttgcactgg cttcaatcca tcacggatat caggcagtgc
     2401 acgttcttgg ataatatatt tggaataacg tccgaagcgg tcacccatca cttcttctaa
     2461 agttaattct tgtacttctt gtcgattttc catcaggtga cctcctattc tacttcaaat
     2521 aactgattgt tttcattttt atctgctcgt tcttcatcta ataaatcatt agaaactgaa
     2581 ggagagattt cagtatcctc ttttttatct aagatactgc catcttcttc gagcgtaaat
     2641 tgcacgtgat tttcgatcca ttttcttcga ggttctactt tgtcacccat cagtgtggtt
     2701 actcgacgtt cagcttgcgc agcatcatcg atacggacgc ggatcaacgt acgggaagtc
     2761 ggatccatcg ttgtttccca caattgttcc gcattcatct ctccaagtcc tttatatcgc
     2821 tgcagcatat atcctttgcc gactttttta atcattgctg ccaattcgtc atctgtccac
     2881 gcatattcaa tgacttgctt ctttccttgt cctttggata ctttatataa aggcggtaac
     2941 gcgatatata ctttcccagc ttcaatcagc ggtttcatat aacgataaaa gaaagtaagc
     3001 agtaatactt gaatatgggc gccgtctgta tccgcatcgg tcatgatgat tactttgtcg
     3061 taattacagt cttcgataga aaactcagga ccgactcctg caccaatcgt atagatcatc
     3121 gtattgattt cttcattttt caagatatct tgcattttag ctttttcggt attgatgact
     3181 tttcctcgta aaggtagaat tgcttggaac tttctgtctc ttccttgttt agcagatccg
     3241 ccagcagaat ccccttcgac taaatacaat tcatttttct tagggtttcg ggattgtgcg
     3301 ggtgtcaatt ttcctgaaag aagagattcg ccttttttac gcttcttccc atttcggctt
     3361 tcttctctgg ctttacgtgc tgcttctctc gcttctctgg ctttgattgc tttacggacc
     3421 aacatctggc tcatttcgct attttcctgc aaataaaagc ccatttgttc actgatgacg
     3481 ttatctacta cggtacgagc aactggcgta ccaagttttt cttttgtttg cccttcaaat
     3541 tgcagaagat tttcaggtac acggatagaa agtacagcag ctaacccttc tctgaaatca
     3601 ctaccttcca gattcttgtc ccgttctttc agcaaaccaa cttttctcgc atattcatta
     3661 taagatttcg tcattgccgc tttcattcca gcttcatggg ttcccccatc ttttgtccga
     3721 acgttattga caaaagataa gacattttct gaatacccgt cattgtattg ataagcgacc
     3781 tctacttcga taccttcttt ttctcccgaa aaataaacaa ctggtgtcaa tgtatctttt
     3841 tcttcattca gataatcaac aaattctttg attccttctt cgtaatgaaa aatttccttg
     3901 actggtactt ctccacgaag atcagaaaga gagattttaa cgccttttag aagaaaggca
     3961 gattctctta accgttcggc taaaatttca tatgaaaatt tcgttgtact gaatattgta
     4021 tcgtctggta aaaaatggac agtcgtcccg tttgcttttt ttgtttttcc tatctttttc
     4081 aacgtaccgt caggtttacc gccgttttta aatttctgct gatactctac gccatctcta
     4141 acgatcgtta cagttagcca tttcgataag gcatttacca cactggctcc tacaccgtgc
     4201 agtccaccag aagttttgta ccctccttga ccaaactttc cgccagcatg cagcacagta
     4261 aaaatcactt caactgttgg tattccggaa gcatgcattc ctacaggcat cccacgtccg
     4321 ctatctgcaa cagttatact attgtcttca tggatggtca catcaatctc actgccataa
     4381 cctgataatg cttcgtcaac tgcattatcg acgatttcat agactaaatg atgcaagcct
     4441 cggctgtcag tggatccaat gtacatccct ggtctttttc taactgcctc taatccttcc
     4501 aatacttgga tggacgagtc attgtattcg ttgtttactt tttttgccaa ggcaaacgct
     4561 ccttcaataa tactttgcgg caaaaccgca ccacgattat catactagaa aaggtcgtga
     4621 aaaaaaagag ggtagacgag aaatcaattt taattatctc ctaaccgctt tttcgacatt
     4681 cccctctatc gatcatctct tctttgtggt catttttatt tttggttttc tttcaactta
     4741 ccaagttcaa tcttaataca acgatccatc acgatatctg tacgtcctgc ttttcttagc
     4801 atctcagctg cttctttgtt ttcaatccct aattgtgccc agaacacttt agcatcagtt
     4861 ttcaaaaaat catctgctac ttcaggtaaa aattcactcc gtctaaatac atctacgata
     4921 tcgattggat catcgatttc tgtcaaattc gcatagactt tctcgcctag aatttcttca
     4981 ccagccaata atggatttac tggtatgatt ttatatccat tgtcttgcaa tacctgtgca
     5041 accatgtaac ttgttcgttc tggtttattg ctcaagccta cgacggcaat attttttgct
     5101 tcttccaaat agttgaaaat cgtttcttgt gttggatttt ttacagacat ttctgccacc
     5161 ccttgctttt ctttttattc catctattat acttgtatct ttcatttttt caattgttcc
     5221 tgttacctat tcatgctaaa ataaaggata gttttcaact tgaaagaggg taaaaaatga
     5281 aattgatctt attacttatt ttagcatatc ttttaggttc tattccttcc ggtgtctgga
     5341 ttggcaaatt gtttttcaaa aaagatatcc gacaacacgg gagcggtaat actggaacga
     5401 ccaatacatt tcgtgtatta ggcaaaacag ccgggattgt tgtcctgctt atggatattt
     5461 taaaaggtac attggctact tgtttgccga tgatcttcca cctttctggg attaaccctc
     5521 tttggtttgg ggtatgcgcc attcttggcc atacatttcc gatttttgct gggttcaaag
     5581 gaggaaaagc tgttgcgaca agtgcaggaa tgcttttagg atttaatcct gtattttttg
     5641 tttattcttg tatcatcttt atcgttagtt tattttgtac aagtatggtg agtttgagca
     5701 gtatgatcag tgcagtattg atcactttat ctacgatcgt ccttccttat gtagctcctg
     5761 tgattttggc taagcccaat tggttactga cgatcattgc ctttttagtt tcttccttta
     5821 tcttttatcg gcataaagac aatatcaagc gtatcagaaa ccatactgaa agtcgaatcc
     5881 cgtttggttt gaatagcagc aagaaaaaat cctgatactt tttcattcca aagagataaa
     5941 acgggagtgt gacaaatcga tgtcacactc ccttattact tacaggatag cttttttaca
     6001 caccttggta aacggtgttc cctgctaact tctcggtcac aacctcttac ttcactgtga
     6061 tggaatattt tgtcttgaag atttcatggg cacctagttg attgatccct actttttcca
     6121 tcaagtttcc actactgttc accgcgtcag cgattccgca ccacggttcg atacaaacga
     6181 aaggcgcttc ttttggataa ggagaccaga tccctacata aggcatatct ttatagctta
     6241 aagttacgct atgggaagat ttttcacttc gaatggcata cgcatttaga ccccttgttt
     6301 caaaaaccaa ggcatcttgc tcaaaaattt cacgattcaa agccagattc gtatttgtct
     6361 gacctaacgt cttttgatcc atatcgatga atgggccttt caatggtagg cgtaatcttg
     6421 atttcaatgg agaaaatgcc agatagaaat cttcaaatga caatccttct tcaagaggta
     6481 cattgaaagc aggatgtcca ccgatagaaa agaacatttc tttttcaccg gtatttgcca
     6541 cttgataatg aaccgtgatg ccgtctcctc ctaattcata gctgatcact aattcaaaat
     6601 caaatggata cttttctaat gtctccggcg tactccttaa gatgaaacta gccatttctt
     6661 gtccatgttc aatgacttca aaatccatat cccgagcaaa tccgtgttgc cccatttgat
     6721 atgttttccc ttgataaaca tactgatcat cttttaaacg tccaacaaaa gggaataaaa
     6781 ccggtgcatg tctgccccaa tacgctggat caccttgcca gatatactct aaaccatgtt
     6841 cttttgattt cagactgatc aattccgcac cgtgttcagc gatttcggcg atcagctggt
     6901 cattttgaat aataacagtc attgccattc ctccaacttc gacttacttt ttaaaatggg
     6961 aaggctggaa caaacatttc tatctgcccc agtcccctta cttctaataa ctgtgttttg
     7021 ctaactcgtc tttaaaacgg gaattcaata cttttaaata agttcccttc atgcctaacg
     7081 aacgagattc aatgattcca gctgattcca attttcgtaa agcattgacg atcacagaac
     7141 gagtgatgcc gatactatcg gcaatattag aagcagtcag acgaccttca tctccatcca
     7201 atgcttcaaa gatagcttgt acagccttca attcgctata agataatgtg ttgattgcca
     7261 tttggacagc cgttgcactc cgtacatctg cttcgatgct tcgagacttc tgataaagga
     7321 tctgcatacc gacaaccgta gctccatatt ctgctaagac tagatcgtca tctgcaaacg
     7381 attgttccat acgagataag ataatcgtac ccaaacgttc gccagctcca aagatcggaa
     7441 cgacagtcgt cagaccaaat ggatatttct ctcttgactc taccggaaat gcagtaatat
     7501 cactagtaat tgggatatta gcttcagttt tcatcaactg tgccactgta tcagtataag
     7561 attcaggaaa ttgtttctca acaaacattg ttttgattcg ttcattgttc acatcgtgac
     7621 gttcattata acctagtaat actccgtcac ttcctatgat ataggtgttg ctgtcaagaa
     7681 taccacctag tgtgacagcc attttatcgt aaggcaaatc tgcttgcatg tcaaaagtat
     7741 tcttttgctg caaaagtgtg tttatcttgc gggttttcgt tagcaagtct gtcattgtcg
     7801 tcctccgatt ttttataaaa tatagcgact taaatcttca tttgccgcaa ttgagccaag
     7861 tttgtcatcc acatatgctt ctgtgatcgt tatttctccc atttgcatat ctggtgcttc
     7921 aaataataga tcttctagta gtttttccaa aatggtatgc agtctgcgtg cgccgatatt
     7981 atctgtgtca cggttgacat cgaaagcgat ttgagcgatc cgttcaattg cttcttttgt
     8041 aaacgtaact gacacatttt ctgtaccaat caatgctaca tattgtttta ttaaagcatt
     8101 attcggttca gtcagaattt tcacaaaatc ttcagctgtc aaatcatcta attctacccg
     8161 tattgggaaa cgcccttgga gttctggaat caaatcactc ggtttagata aatggaacgc
     8221 tcctgaagca atgaataaga catgatctgt ttggatgatc ccgtattttg tatttacttg
     8281 tgaaccttcg acgattggca atatgtctct ttggacgcct tctctggata cttctccaga
     8341 ttgctgtgat ttagaagtga tcttatcgat ttcatcgata aaaataattc cactttcttc
     8401 cgctaatttg attgcctcac tatggatatc agcatccttg actaattttg ctgattcttc
     8461 cttgatcaat aactctaaag cttctttgac tgttaccgtc cgttccactt ttttcttcgg
     8521 tgtcaaagca cctagagttt catttaggtc gatccccatt tgctccaatc cattgttcat
     8581 cattggtgca ggtttctttt ggtcttcaac ttcaatggtt acttcacgac tatccagtaa
     8641 acccttttgt agttgttcca agactgtacg gcgattgatt cgaatatctt ctgtcacttc
     8701 ttcttgcggt tcagcggtat tttgctgact agcattaaaa agattcatca tttgttcaaa
     8761 ttgattagtg gattgtttct gttctttttt gataccaggt accaagattt ttaccaaacg
     8821 tttttctgca ttttttttag cacttgtgta tacacggctg tactgctctt tttctacgat
     8881 ttggatcgca ttttctacta aatcccgaac cattgattct acatctcttc cgacataacc
     8941 gacttcagta aattttgttg cttcgacttt gacaaatggt gcattgacga tttttgccaa
     9001 acgtcgtgcg atttctgttt taccgacccc tgtaggtccg atcatcagca tattttttgg
     9061 tgtaatatct tgttgcattt tttcatctaa ctgcaaacgg cgatagcggt tacgcaaagc
     9121 aacggcaaca gatttttttg ctgcgtgctg tcctacgata tattcatcta attcacttac
     9181 gatttgtctt ggtgtttgtt ttaattcata catatctact cacctcttac agttcttcta
     9241 cgataatatt atgattagta aagatacaga tatctgcggc aatatttaac gcattttctg
     9301 caatttcttt cgcactcatg tcgttttgag catagttttt cattgctcgg gctgcagcca
     9361 acgcaaaatt ccctcctgat ccgatagcta agataccatc atctggtgtg ataacttctc
     9421 ctgtacctga aacaagaagc atttctttat cattcattac gatcagcatc gcttcaagtt
     9481 tttgcataga ttgctgtgtc cgccattctt gagctaattc gacagctgcg cgttgtagat
     9541 tcccgttata ttcgtttagt ttgccttcaa atttttcttc taaagtaaac gcatctgcaa
     9601 cacttccggc gaaacctaca acaacttctc cattgtagat acgtcgtact ttctttgcag
     9661 tgcctttcat gacaacagat tcacccattg ttacttggcc atctccagcc atagcaaatt
     9721 tcccgtcttt ttcgacggca cagatagtgg ttgaatgaaa tggtgattcg accatgtttg
     9781 tttcctccta aatttgttct tttccttatt tttacgctct tggatggaaa gaacgatagt
     9841 ttttttgtaa actttctttt gttacatggg catagatctg ggtagtcgat aaattggcat
     9901 gtcctagcaa ttcttggact gtccgcaaat ctgccccatt atttaataaa tgagtagcaa
     9961 atgtatggcg cagcatgtga ggatggatat cactatccaa actgcttttt ttgatcattt
    10021 gattcaagac atattcaatt ccagtaggcg tgattggttt tccatgatga ttcacaaaaa
    10081 cgatatcatg ctcttcgtga tattttgtca tcaatacctg gcggccttcc ctgaaatatt
    10141 cttgcagagc atcttgagca aaagaaccta gaggagcata tctctctttg ttccctttac
    10201 catggatcaa catgacctct gaatcaaaat caatgtctga taccgacaaa ctgctacact
    10261 cacttaaacg gatgcctgac ccgtaaagga cttccagtaa agcgcggttc ctcaaatcca
    10321 aaggactatc tcctgctacg ctgtcaaaaa gtgcttgcat ttcattttca taaaaaaaac
    10381 gtggcagtct caaatttttc tttttgagat gaacgtaaga aaatggattt tcttttatca
    10441 cttcttcttt gagaagatac tgataaaacg aacgtaggct ggctatcttg cgactgatag
    10501 aatttctgct atagctagga cgatgatcag ctaatgcact caaatagaca cgaaccgtaa
    10561 aatattccgc cttcagcaga tcagcgtctc cagattcctc caaaaaatgt ttgaaatgga
    10621 gaatgtcttc ttcatatgct tctttcgttt tttctgaata tcctctttcg acaatcaaat
    10681 aacgcaaaaa tttttgttcc cacgtggctt ctgtcatttt ctcaccttcc ttttgtccca
    10741 gagaataatt tagcacagcg tttataaaaa gacaaataaa ttgtcagaat ttaaccaata
    10801 tttctaagtt tgttcacaat tggcgcaatt cctcacattt tgtttgagaa attcttaaga
    10861 aaaacgcaag aaaaagagcg agactatccg tctcaccctc ttcatggagt ttccttactc
    10921 atttgggatt gcagtttttt ctaattctgt ttttattgcc tcattagctt ttaaagctcg
    10981 ttgtgcaatt gcttcatatc ttgctttttt gtctcgaatg cgctctggca gttcaggaaa
    11041 cagaccatag ttggcattca tcggttggaa atgttttcct tccgcatgag taatgtagta
    11101 tgccatactt ccaatagctg tttcttgtgg aaactcgact ggttccattt cttttgctaa
    11161 gcgtgcggcg ttgattccag caagtagtcc gctcgctgca ctttcaacat agccttctac
    11221 accagtcatc tgacctgcaa agaacagatc ttcgcgtttc gttgattggt aagtcggttt
    11281 cagcaattct ggcgaattca taaagctgtt tcggtgcatc acaccatagc gaacgaattc
    11341 agcattttct aacccaggaa tcatccggaa aacacgtttt tgctcgcccc atttcaagtg
    11401 agtctgaaag cccacgatgt tgtataaaga agctgcagca ttgtcttgac gcagctggat
    11461 aacagcataa ggacgtttgc cagttttagg atcttccaat ccaactggtt tcataggtcc
    11521 gaaaagcatc gttttgaatc ctcgctgtgc cattacttca attggcatac atccttcaaa
    11581 atatttttct ttctcaaaag atttaagttc tgccacttcg gcattgatta gtgcctcatg
    11641 gaaagctttg aattcctctt ctgtcatcgg acagttcaag taagctgctt ctcctttgtc
    11701 atagcgggac ttcaaatata ctttatccat atcgatcgta gctttgtcta cgattggtgc
    11761 agctgcatca tagaaataaa aaccatctga accattgaat gctttgatgc tttctgctaa
    11821 tggatgagaa gtcaaaggtc ctgttgctac tacggtgatt ccttccggta tttcagtaat
    11881 ttcttcgttt atcactgtta ctaatggatg ctctttgact tttcgggtaa ttgtttcaga
    11941 aaaagaatcg cggtcaacag ctaaggcacc accagctggc actgctgttt catctgccga
    12001 agtgattact accgaatcca atcggcgcat ttcttctttc aataacccta ctgcattagc
    12061 caaactgttt cctcttaatg aattggaaca tactagttca gcaaaattac ttgtgtgatg
    12121 cgcctcagtc gatttgactg gacgcatttc atataaacgg acagggactc ctgcttgtgc
    12181 gatttgccaa gcagcttcac ttccggcaag ccctgctcca acaacattta ccattttcaa
    12241 tgaaagaacc tcttttctat tatttttgga tgtcttcttc gtaatctcca tttacacaga
    12301 ctacttgttt accgcctttg actttcttct cgaccagata tccgtcacat tttggacaat
    12361 ttctgcccac tggtttatcc caagaagtga attcacattc tgggaaacgg gaacaaccat
    12421 agaatagtct gtttttctta gattttcgtt caatgacttg tccttcatga catactgggc
    12481 aagtcacacc gatttctttt acgattggtt tcgtattccg acaatcagga aaattactgc
    12541 aagcataaaa cttcccatat ttccctaatt ttattaccat cggatgtcca cagacatcac
    12601 aatcgaatcc tgctggttca tctttgattt gaattttttc gattttttct tccgcattcg
    12661 tcagttcttt ttcaaacggt ttatagaaac gatcaaccac tttgacccac gcttccgtgc
    12721 cttcttcaat tttatccaaa tctccttcca tttctgctgt gaaatggata tcgacgattt
    12781 gagggaagaa ttcacagatc agtgaattga caatttctcc tagttcagtc ggctcaaatc
    12841 ttttttgtgt caattttaca tagtagcgtc tttggatcgt atcaagtgtt ggtgcataag
    12901 tggaaggtcg ccctaccccg ttttcttcta gtgcacgaat caacgtagcc tcactaaaac
    12961 gtgctggtgg ttgagtaaaa tgttgttttg gttcaatatc aacagattgg actatatcgc
    13021 cttcttcaag ttctggaaga atattttctt tctcttcttt gccgtcatct ctaccttcca
    13081 catacacttg catgaatcct ttgaatttga tttttgaacc gttcgcaatg aagatgacac
    13141 cattttgttc taatgtcact ttcattgtat ctaaaatagc tggtgtcatc tgactagcca
    13201 caaaacgtga ccagatcaat gtataaagtt tcaattgatc tttatctaaa tattgtttga
    13261 gttcatctgg tgtacgaagc acactcgttg gacgcacagc ttcatgggca tcttgtgcgc
    13321 cttgagcatt tttgatcttt cggtgatcat gtctagaaaa ttcttttcca tacgtatctt
    13381 caataaatgc tgcggcctct gcttttgctg tatcggcaat ccgggtagaa tcagtacgca
    13441 tgtatgtaat caagccgact gttccttgtt tacccaaagt gattccttca tataattgct
    13501 gtgctaccat catggttttt cttgttcgaa agtttaactt acgggcagct tcttgttgca
    13561 ggctacttgt agtgaaagga ttcgcagggt ttcttttgcg ctctttcttt tctacttttt
    13621 taacttcgaa gtctgttcca tcaattctag caatgacttc ttttacactt tgtgcatctg
    13681 gtaatttctt tttcttaccg tcgattcccc agaaatttgc tttgaatttc ttgcgagctt
    13741 ttttaaaatt accgtcgatg ctccaatatt cttctggaac aaattctcgg atctcttttt
    13801 cacggtcaat aataattttt aaagcgacag attggacacg tcctgcactt aaccctttct
    13861 tgaccttacg ccagagaata ggactgatcg aataaccaac gattctgtct aaggtacgac
    13921 gagcttgctg tgcatctact aaatctacat cgatcgttct tggttcctta aaagctgctt
    13981 tgactgcgtc ttttgtgatt tcattgaaga ccacccgatt tttttctttc agatccaacc
    14041 caagtaggta cgctaaatgc caagcaatcg cttctccttc tctatccggg tcacttgcca
    14101 agtaaacttt ttgagctttt tttgctgcgg ctttaaggct tttgatgaca tcgccttttc
    14161 cgcgtataga aatataatgg ggttcataat tgttttcaaa atcgataccc attttacttt
    14221 tcggtaaatc tcttatatgg ccaacactgg ccattacttt atagtttcgt ccaagatatt
    14281 tctcaattgt cttggctttt gcaggtgatt ctacaatcac taaatattta tacgccatta
    14341 ctgaatggac tcctttccat tgtcgtgttc ctactattaa aagaggattc atacaaatcg
    14401 tagctaatca tatccattca gaaaacgttt gtcaagaaaa gcaaatgaaa agtatggtgt
    14461 tattctttaa attctgccaa gatatcttca cccgaaaccg tgcaaactgc accgtcttgg
    14521 atcaaatgat gacatccggt agaatgttct gttaaaatat ttcctggaac agaaaaaact
    14581 gttcttccaa gatccaatgc ttgctgtgct gttatcagag agccgctttt tttcttggct
    14641 tcaaagacac atgttccttt agacaaagct gcgataatcc gatttctcat tggaaaacga
    14701 tgctttttcg ggccggattg aggaggatat tcactcaaaa gaagatgatc atttgcaatc
    14761 acctcttgca agtcacgatt ttcagcagga tagacttgct ctatccctgt tccaatgact
    14821 gcgattgtcc gtccaccatg agagattgct gcttgttgac cgtatgtatc tatccctttc
    14881 gcgcagccac tgacgatcac atatccagct tctaccactg gttttagtaa ataataaact
    14941 gtttttttgg ctaaagcaga agtgtgtctt ccaccaacaa cgcttaacat gttacaagaa
    15001 agtaaagata gatcaccatt ataaaacagt acaattggcg gataggtcaa gtgaagtagc
    15061 tgagggggat atttgggatc aaagcaagtg ataaacgact gtttcgattg gattttgccc
    15121 cagttagcgt gaatttcctg ccaacttttg cgaaacagct cccgatgtgt ggttatttta
    15181 cctatcttaa tgatgtcttc aaatccgatt tctttataag gatactgcat catccagtta
    15241 gcaagtgccc attttccttg actactgatt ccttttgcat aagcaagttt caataaattc
    15301 tcttctattt gatacatcat aaaaccgcct ttcgtctctc tttctaataa gatacgtaaa
    15361 agcggctgtt ttttattgta aatatttttt tacaggtgca aaacttttac gatggattgg
    15421 cgtaattcct tgtcgttcaa ggccttctaa gtgttccttt gttccataac ctgcattatg
    15481 cgagaaacca tatccaggat aaagcacgtc atattctttc atcaattggt ctcgatatac
    15541 tttagcaatg atacttgcag cagcaatcga cacagatcgt gcatcccctt tgattatttt
    15601 ttcctgctgg ataggcaaat ccaaggtcat cgcatcgatc aacaaatagc ttggtacaat
    15661 ggacaatttt tctactgctt ggatcatcgc taatttactt gcttcataaa tattcacatc
    15721 atcgattgtc tgctgatcaa cgatcccgat cccgattgcc agggcttttt cttgaacttg
    15781 ttgataaaga agttctcgct ttttctctga taattgtttg gagtcattca gccctaatat
    15841 gatctcattt ttcggcaaga taactgcagc tgccacgaca ggtccagcta atggtcctct
    15901 tcctacttca tcaatgccgg caatccattg gtgaccttgt gcgtaccctt gcttttcaaa
    15961 gcaaaacatt tcttcatatt tttccttaat taatgcttcc tttttcaatc gtcgttcaaa
    16021 agaagccagt gcttgctgca cgcctttgcg tggatcattt cttaatgatt ctagtgtagg
    16081 atcatctatt ctctgtatgc ttttcaatcg ttctttgata ctttggatgg attcagtcat
    16141 cacttttttg ctccatttct tcgcaacgat ccagtgtgta tcgtccaagt tttccttggc
    16201 gaatatcatg cacgactaat tcgctgccgc gatcatagtc ttctttatac ccacgttttg
    16261 ctgtaatatc catcagtaat tccggtgcca atttttcttc ttgctcgatt gataaaccat
    16321 aacgatcgct gattcttcct gaataatatc gggcaaaaaa gtctaatccg taaatcgcta
    16381 aatcatctaa atggacaagc tggtctttga tcgcgcctgt cagcgctagt tttttgccga
    16441 tttcttcatc ttcaaatttg ggccataaaa tccctggtgt gtctaacaat tccaactcat
    16501 tacctaaacg aagccactgc tgaccttttg ttacgccagg cttatttcct gtctgtgcaa
    16561 ttttcttgcc tactagtcga ttcatcaacg tagatttccc aacatttgga atacctaaga
    16621 ccattgcccg aatagcgcga ggcttgatcc cccgagcagc atctcttgcc cgtttttctt
    16681 tcaatgcttc tttagccgca ggtactagac ctttaattcc tttactttct tgtgccgtga
    16741 tagctaatgc aagatggcct tgtttacgaa aatattcttg ccacagcttt gtctgttgtg
    16801 gatctgccag atccgcttta ttcaataaaa caaggcgagg tttttgctga atgatctgat
    16861 ctagcattgg attacgagaa gataaaggta atcgtgcgtc taccaattca aatacgatgt
    16921 ccacatattt cattttttca gaaacttctc gtcgggcttt tgccatatgt cccggaaacc
    16981 attggatggt cattgttctc tccattcctt tcataccgga atattccccg gctttacttg
    17041 ttttttttct ttttcaatat aaattcactt ttttattata aagaaattcc atctattagt
    17101 taagtgaaag tgaaccagtc ctcattctat cacatcttca cttttttgat gatgtaaatt
    17161 tttattttgg tttctatata tgaatctaaa tttttgacaa cgtttcctaa ataagagatg
    17221 atagacgaac aaaacagaaa ggagacgaaa caaatgaata gtatggtttt tgttaatttt
    17281 cctgttgctg atgtcaatcg ttccgttgct ttttatgaaa agctgggttt taaaaaaaat
    17341 gaagaatttt ctactgaaga agctggttca atggtatggg atgacacttt ttgggtaatg
    17401 cttctctctc atgattttta taaaaaattt ataaaagata aagaaatagc tgataataaa
    17461 aaaacaagtg gtgctttgat ttcgtttagt gttgaaaacg cggatgaagt aaaaaaattt
    17521 gctcaaattg caaaagaaaa tggtggtact ttccacgaag tagatatggg aatgcctgaa
    17581 gaagaaatgt tttcattaga agtccaagat ctagacggaa atacattaga acccgtatgg
    17641 atgaagatgt aagcagataa ctaatctgac gttttttata acaaaaaaac aaaggcggat
    17701 gatacgataa gtattctccg cctctatttt tttcattcgt acaatctctt ttttacagtt
    17761 tataaaagca gtcttctcac ccttttttta attgttagat gccagtgtat gtaaatcacc
    17821 aatgtgtcat gacacattgg tgattttatg gtatcctttt attattaact gacaaaggag
    17881 agaatatttt gaacactttg attgcaaaag acgtttttag attgcccgaa atgaatgcaa
    17941 gattgttgtc gacctctgct cttttattag cccttgatgt catcttatac aagatagcga
    18001 ttggtcctgc ttattttcaa atcacattcg gatttttaag tatggcgctt atgggttatc
    18061 tatatggacc gatctgggct ggtttgcttg aaatgttgtc gaacacttta aatttcacga
    18121 tatttggttc aggaacgttt caagctgctt ttcttatcac ggctttcctt ggtggattta
    18181 ttaatggctt atttttatat cataaaaaga taaacctgcc ttccgtcatc gctgcccaat
    18241 tattgattat gatcccagtc agccttttta tcaattcttg gctgatgtct gttttgtttg
    18301 gtgcagattt caaagtgatt tttctaggta gagtcatcag gaatatgatc caaatcccta
    18361 ttcaaataat ggttgtttat tcatttatca aaactttaga ggctagaaaa gtgtttaaac
    18421 gagctgtttg attttacgta ctaaggtagt aaactgattt tggattaaac aataaagcgt
    18481 gcagtctcaa cagattgcac gctttattgt ttctcactgg atccatttta tttcatcaag
    18541 tggataatag acaaatcttg ctttacctag aatatcagtt ttattgatcg tgccaaacga
    18601 acgactatct tttgaaactc ttcgattatc tccaagtaca aaataattat cttccggaag
    18661 cttggattgt cccgttagct cttgtagtgt aaagtccgtc gtataggatg catttgcatg
    18721 atctgatttc aggtttttag ttagataagg ttccttaact actttcccat tgatcttcaa
    18781 ttgatcattt tggtagctga cattttctcc tggaagaccg attactcgtt tgatataaat
    18841 cgtgccatct gctaattgaa aaacaacaat atcaaatcgt ctgatctccg aaaatttttc
    18901 catcacaacc atatcacctt gcttcaacac gttttccatt gaattgcctt ccactggtac
    18961 cgggatgaat aaaaatcccc gcaacatgaa cgcaaggaat acagaaacaa gtaagtattt
    19021 gaatacaagc cagaagcgat taatatagcg ttgttttttt gtcaatctct atcaatccat
    19081 ccctcgtttt ttcattcttt ctttattata agaaaaatat caaaaaaatg cgactagata
    19141 gctgaaataa aaataattct ttcaattagg ctattggaca aaaaactttt ttgatcataa
    19201 agtacaaaac tatctcttat atgtcatgat tattttctaa atatttttcc catgcttcgt
    19261 caaagatatc catggacggc aaatagtcga cattcagttc cagataatta gaaatttctt
    19321 cgtagctaga gctgtgctta ggaaattgga tgtctttacc ggcttctgta gcgaaaacag
    19381 ataaagcatc atgtgtgcca ccgcctcgca gtgtcattaa ataatgaaaa aagcttcgat
    19441 tcacccttcg ttcctccaat tttcttcgat aaaggcagcc cggcgtgcat ggtttctttt
    19501 aaaattttca ggatgctttt tataatactc ttgatggtct tcttctgcta gataaaatgg
    19561 ttgggctggt tcgatttttg taacgattgg ctgttcgaaa cgtccacttt cagctaactg
    19621 tttcttactt ttttcagcaa tgatccgctg ttcttctgtc aaataaaaga tcaccgggcg
    19681 ataattgtca ccgcgatcct cgaattgtcc gaaagcgtca gttggatcag tttgctgcca
    19741 gtaaagttct actaattgtt catatgaaat caatgttgga tcatagataa tctccactgc
    19801 ttctgtatgt ccagtcgttt ggctttttac ttgttcataa gtcggatctg gtacatgccc
    19861 tccagtatat cctgacatca ctgtatggat accaggaagc gtgtcgaaag gctggatcat
    19921 acaccagaaa cagcctcctg caaatattgc tcgttccatt atgattcccc ctctaatact
    19981 actcatccga tgatttttta ttttcttttg tcttgctttc agtactgctg gtgctagttt
    20041 tgttggtatt tgagttgttt gaagcatcag aggtatcttt tggcaaatat agactaaacc
    20101 gaatgtcatc atttactaag tcgattttat ctgctttaat atacatcccg ttttgcattc
    20161 ggaattgatc caacctaagc atgatagtca gatcatctgt attgacttcg atccaatctg
    20221 gtaatttata gtttctcttg atcatattca tcacatcttt gattggcaaa ctcaatgttc
    20281 cgatagaaag acttctagct tttagttgga catttccgtt ttccatcaca tacggatcaa
    20341 aatataaata gaaatcgata ggaaaaccta gtacttcgaa agtaccattg agtagtgctt
    20401 cattttccaa ataaaattta tattcaatat cactatcttt ttgatactca ctaaggaaaa
    20461 agctgatgat ttgattgact ttttctttat ttgaattgat cgttaagaca ggatctcctt
    20521 gtctttccgt aagagctggt atttctggga gttctggttc ccgattagca aaaatacggc
    20581 tgcctaaaaa tacggtcgaa ccaagtacta ccccaagaag gataaggaag gcgaatttcc
    20641 agtaatttgt tttctttgtt ttgtttgaag atacgtcaga tcttgttttc atgtttattg
    20701 atcatcctcc ttctctagcc attggttttg tgtctcgatc agctgatctc tcactgcatt
    20761 tgccatcaat tgataaccta aattatttgg atggaaatga tcttcttcat agagcacatt
    20821 atttttgatg ccatttagat tttctgtcgt gctagttgtt tgatctgttc cttcttctgt
    20881 gacacctact tcctgattca atccttgata aagcaaatca ttgattggga taaagtagca
    20941 gttcggcatt ttttttgtca ccgtttctgt tcctttgttc caattgttaa caattgtctg
    21001 catgtcagtg atctcaggaa agttcaaata aaatggattg tagatgccta aaatgtaaat
    21061 aggtgcggtt ttattgaggg atcgaaattc ttccaatagt tctgtgacat tttcctgata
    21121 gtttttcagt ggctttttaa aggaattgac cgttaacccg aataaattat tttggataac
    21181 tttcatcaaa tcattaccgc caacagtcag tgtgataaaa tcagctgttt tgatattgtt
    21241 tcgaatttct tcttttgttt ttactcgctt taagatctgg tcacttcgtt caccatttac
    21301 accatagttt tctgtttcaa ccgcggtcaa attataacgg tcttttagat catttgcgac
    21361 aaggggaacg aatcctcctt gcttggtttg atctcctact ccttcagtca gcgaatctcc
    21421 gatagctatg tagtgaagtt tttctttttt atttggatct tctctcacag tagttactgg
    21481 tttcattagt gggccagctt tcggtataga agcagctaaa cctgcataga tgatgatcgc
    21541 aattaataat gggaacaaaa cgaggatcag atgtcgtttc gttaatttca ttttttcacc
    21601 tcttgtattc gattggttct aatgttatca aaaattttat caaaaaggta gtctttatga
    21661 aaaaagaaaa caattatttt cctaatttta taaagaaaaa gagaataagc tgcaagcctt
    21721 tcaggctgag ggcttatcct cttttcgact aatctacata atacatgatt gcaaacgcgt
    21781 ctttaccagt atgcgtagcg ataaccggat tcgtatgcag tacagggata tgcatgtccg
    21841 ggaataattc ttgcaaaccc tctttgaatt cttgcgccaa ttcttttgca tccgcatgtg
    21901 aaataccgat ttgtcgcaca tttggcaatt ctttcagttc atttttcaaa ttattaaacc
    21961 atttatcgaa cgttttcttt cctcgcccct tagttacagg gattaattca gaatgggcga
    22021 aattcatcac cacgcgtatg ttcaaaacac tagacagcaa accagttgtt cgactgattc
    22081 ttccaccttt taccaagtta tctagtgtgg atattccgat gtataatttt gtattgtctt
    22141 gtactttttt gacttcttca aggatttcct ctactgtttt accttctttt gctaattcag
    22201 ctgctcgaat tacctgaaaa gataatcctt ggtcagtggt atcactgtcg ataaccgtta
    22261 ctttcgtttt tgttagatta ctggcttgtc ttgctgcttc tactgttcca ctcaagcctt
    22321 ttgtcatatg gatcgaaatc acttcactgc cgtcttctcc tagctcatca tacatcgaga
    22381 taaattctcc aatcggtggt tggcttgttt tgggcagatt ttttgctttt gccatcattt
    22441 ccataaatct ttcgccgtct agttggtcat catcgggata tactgttccg tcgatcatga
    22501 tggatagcgg catgacacga atgcctaaag catcgcgtac atttttttcc atcgtacatg
    22561 aagaatctgt tacgattttt acatttgtca ttattttctc tctctctttc tttaacaaga
    22621 tgccttattc atgttaaact acatgtaaga caatttctat ttttagtata acagacaaat
    22681 aatgattttt cattaattac acctagtaaa ggagccgttt tcatggaaaa aacgaaattt
    22741 aatcgaacgt atgaaatatt aaatgaagtg tttaatgcag tcacccatgg aattgggact
    22801 ggattgagta tcgcgggact agtggttctt ttagtaaaag gtgcccactt gcattcctcc
    22861 ctccatattg tctcttatgc tatctatgga tcgatgatga ttcttttatt tttaacgtct
    22921 actttgtttc attcattgat ttttacaaaa gcaaaaaagg tgttccaagt attcgatcat
    22981 agttcgattt ttcttttgat tgcaggaagt tatactcctt tttgtttgct gagtatccga
    23041 ggatggctag gttggacttt atttgtatta atctggttgt ttgcgattct tggcattata
    23101 tataaagcgt tgacgttgca taaacgggag agagtatcaa aagtatctac gatcatctat
    23161 atttttatgg ggtggctctg tgtcgtggct gctgttcctc tttatcactc tcttggaatg
    23221 actggtgtta ttttgatggt agcaggcggg ctttcttaca cgataggcgc attcttttat
    23281 agcttgaatt ctatccgcta tatgcatgtt gtttggcatt tgtttgttat gttaggtgca
    23341 ggttttatgt acttctctgt tttattcttt acttaataaa aaaaaataaa gctatggatg
    23401 ggacagctct aaataacagc tagtctatcc atagcttttt tatatcgtca attcgcctgt
    23461 cccgcttttt acaggattct cattacgctg atacgtttca aattgatgcg gataacgatt
    23521 tttttcatct atttctcctt gactagtatt gatcagtgac caatcagacc agtcaacagg
    23581 tggaaaataa gcatctccat cgaatacatg atggatgact gtacggtata atatcgtaca
    23641 aaatggcaga aattcttgat aaacagctga ccctccagcg atgaaaaaga taccgtctgt
    23701 ttctttttcc agagcaagca cgtcttccac actatgcatg acatgcacgc cttctgcttt
    23761 ataggaagaa tctctcgtca aaacaatcgt ctgacgattc ggcaacggac ggctacccat
    23821 cccttcgaaa gtttttcgtc ccatcactag tgtatttgct tctgtcattt gtttgaagaa
    23881 tttcagatca tttggcaaac gccaaggaag acggtcttct tttccaatca atccgttttc
    23941 atcctgtgcc caaattgcag ctaacatttt ctcatccttt ctgattctaa acagcgatag
    24001 gagctttgat cgccggatgt gggtcatatc cttctaattg gatatcttcc atctcaaaat
    24061 caaatactga ctgcttttcc tgattcaaaa ctaaagtcgg aaatgcgcgt atttctcggc
    24121 tcaattgttc tttcatttgt tcgatatgat tgatataaag atgagcgtct cctaatgtgt
    24181 gaacaaattc gccaaccgct aaacctgttt catgtgcaat taggtgagtc agcaacgcat
    24241 aacttgcaat gttgaacgga acgcctagaa acacatcccc actgcgttga tacaattggc
    24301 agcttagccg tccctcttga acataaaatt gaaacatcgt atgacaagga ggcaaagcca
    24361 tgctaggaac atcttccgga ttccatgcag aaacgatcaa tcttctagaa tcaggagtct
    24421 ttttgattgc ttcgatcact tctttgattt gatcgataaa gccaccgtct tttgtttccc
    24481 agtgacgcca ttgatagccg tagatgtgtc caagatcgcc gtatgtttca gcaaaggaat
    24541 catcggttag gatcttctcg caaaaaagct tgctctgctt tttatattct tcattgaatt
    24601 caggatctgt caaacatcta tggccaaaat cagtcatatc tggtccatta tagtctggac
    24661 ttttgatgta gcgttcaaat gcccattcat cccaaatatg gtttttattt tgtaatagat
    24721 agcggatatt cgtatctcct tttaaaaacc aaagcaattc gcttttgatc aatccaaaag
    24781 gtactcgttt cgttgttaac aaaggaaacc ctttttgcag atcaaaccgc atttggtatc
    24841 cgaataagct taatgtgcct gtgcctgttc tgtcttcttt acgatgccct tcttccaaca
    24901 attttcttcc taagtcaaga tacgcttgtt ccatcctttt tcctcctaat cttctaccca
    24961 ttcactcaag tattcccacc gtgccatttt ttcttcaagt tgtgcttctg tttcagatac
    25021 gtcgttttgc aattcttgta atcgagtgaa attatctcct tgatgattca tctcttcttg
    25081 gagcaatgag attttttctt caagttctgc aatctcatct tcaatcgttt cccattcttt
    25141 ttgttccatg taagataatt tcttcttttc agcaggttcc ttgctctgta tttttggttt
    25201 cgctttttca gcaggctgct gggtctcttt ttgcttcagt aaataactgg acatgtttcc
    25261 gtaataaagt tcttgttttc cgtttccttg gaatactaat aacttatctg ctaccttgtc
    25321 caagaaataa cggtcatggg aaacagtgat cacagcacct ggaaaacttc taaaataatc
    25381 ttccaaaatc gtcaatgttg ctatgtccaa atcattggtc ggttcatcca ataataaaac
    25441 attaggttgc tggatcagca gtttcaacaa aaataaccgg cgtttttctc cgcctgaaag
    25501 tttgcctatc agtgtcccat gcataaatct tggaaataaa aatcgttcaa gtaattctgc
    25561 tactccgatt tgactgccat ctgctgtttt tgcttcttca gcagcttctt gtaagtaagc
    25621 aatcatccgt ttatctggtg ccatttcttc attttcttgt gtataatacg caagatgaac
    25681 cgtttcaccg atagacattg taccgctatc caggggaatt ctgccagcta gaatattaag
    25741 caatgtcgat tttcccgcac catttttacc agtaatacct agtctttccc gagattgaat
    25801 cagtaaatct aaatgttcta gcagtgtttg gtcatttata cggtaactgc catctttgat
    25861 ttccagtact tttttcccta aacgttgtgt cgctaggttc agctctaaat catcttcttg
    25921 gtttacttgg tacaagttct cctttagatc ttcgaaacgg ttgatccgtg cttgctgctt
    25981 ggtgccacgt gcctgtacgc cagccctcat ccaagctaat tcctgtttat aaagccgctt
    26041 gcgcttttct tcttgttcta cttctacacg atcacgttct gctttttcta agacgtaagc
    26101 ttcataattt cctttatact cgtataattt tccaaatgaa agttcgaaga ttcggtttgc
    26161 tactctatct agaaaataac gatcgtgggt aaccatcaat agtgcgccac ggtattgttt
    26221 caaatagttt tccaaccact cgatcgcttc ataatctaaa tggtttgttg gttcgtctag
    26281 taatagtaaa tcgggttcat caatcaacac ttgcgccaga ctaactcgtt ttttctgacc
    26341 acctgataaa gtactgattt ttttatctaa ttcactgatt cctaattttt gcaaaataat
    26401 ctttgcgttg gtatctgtag tccaagcatc ttctttattc atttgttctt ctgctttagc
    26461 ataacgtttt tgcacatcag ggtcttctcc gttttcccct agttcgatca atgcttcctc
    26521 atatgctcga acagtttgga tcaaggggct gtttccttga aagactgctt ggagaacagt
    26581 taattcatcg gaaaattcag ctgcttgaga aagataacca atacggtaat cagttggata
    26641 aaacactgtt tgccgatcac cgtcgccgct atcgataccg gcaataatat ttaagagact
    26701 tgttttaccc gtcccgttcg tcccaatcaa cccgatacgg tctttttcgt ggaccaaaaa
    26761 agaaatctgg tcaaacaaat ctttttcacc ataagttttt ttgaggtcag ttacttttaa
    26821 ttctttcaac atgttccctc cttatcttgg atattgtatc ataaaaatag tgaacttcag
    26881 gaaaattttt ttggtatttg ttctttttgt gttctcaaaa aaagaacagg accgattcga
    26941 tcctgttctg atatgttttg ttttttataa aacttgaaaa tttttacctt tttattttat
    27001 tggactcgtt tttttgactt tgctcgaaac gcaaatcgga aagaaaagtt atcagatggt
    27061 ttgttcatcg tataagattc taacaaattg atattcctgc gatagctgtt cgcagaaaac
    27121 gtcgtgattt tctcagcaac ttcgtattca tcaatgattt ttctttcaag ataataacct
    27181 cttagcattt tttttgtaaa cagactatct tgctggatca tccacgaaga aatcaaattc
    27241 cccgagttca tttttattcc ttcaagtttg cgttgctgga taaaaaattg aaccatcgtt
    27301 tcatcataaa tatcagtcaa gttatctaaa ctttcaataa tcaactgagt atttttttga
    27361 tatgtctctc tgatttcttg gatatcttca tcactaataa atgtctgacg atcagcatgt
    27421 cttctttgcc aaaacatttt cggatggaga acgattcgca ttaacctacg gacaacaatg
    27481 aaccaaaagc cgataaaaga caaaatctgg cttgtgatag aatgttcgaa tcgagaaaga
    27541 aaacgggagt aaaaacgata accattagaa gaaagcttgc ccgaacgata actttcatcc
    27601 aatccatccc gttcgatcga caaaatcagt gcttgtattt cttgtacttc ttgcttttca
    27661 tcatcggtta aatcttccaa gtacagatca cgtatccgtt cttgataatt ttctatcact
    27721 gcttcagtgg ctaaaaattc ttttgtatta cgatcaattt cctttatttc ttttcgcaaa
    27781 acttcaacga cctcttctaa aatcatcaaa gcattcaaat ccgtgctttt cgcttcctct
    27841 gtttccgtca gcataggcaa gacaatgatc cctatgacca aagtcactaa gatgacaccc
    27901 gccgtcagaa acaaaagcaa agaccgctgg taaaacatca tattattgat tgaaaatggc
    27961 aaaataaaaa tcgtagccaa actgactgtt ccctttacac cgccaaatgt taagatcaag
    28021 atctcgttca actgtttttt gaacttttta ctgccatctt tgaatacata aaaaagactg
    28081 atagaaatga atctgatcac aaaaagcatg acagagatta atacgataat cgctaataaa
    28141 agaccgtttg gatataaacc gtctccccat actggcgaga acacttgcgt caattcgatt
    28201 cctaaaaata taaatactaa tgcattcagt gtaaaagcaa tagttgtcca tgtactgtgg
    28261 gacaagctcg acaattctgc atcaaacaca gagattttcc taaaaccaga agcttggaga
    28321 atacctgctg ccactgcagc aatgattcca gatacatcaa atgcctctgc caatacatag
    28381 gctagaaaag gaagcaaaag ttcgatcagc agataccctg tgacatcttg tgctgatgct
    28441 ttttcgatca aatgaattat tttttgtttg aaccagacaa gcaaaaagcc gatcaaagct
    28501 cccccaatac tagaaactac tagactcatc cccgcgttta ctgctgaaaa agatccggtg
    28561 atcagcgcac caagagcaaa ctggaaggca gtaacaccag atgcatcatt caaaagacct
    28621 tctccttcca aaatatgcat cgccttttta gggatattca ctcgtccaga aagagaactg
    28681 actgctaccg catctgtcgg acctaacgct gctccaaaag caaagcaggc agcaagtggg
    28741 acacttggca acaggaatga taacgtcgca cctaccccga caagggtcaa aatgactcct
    28801 ccaaatgcca agaacaaaat tgtcccgaaa tttttgagaa tcgaagaaat atctgctttt
    28861 tctccttctc taaataacaa tggtgcaata atcataacta agaacaattc aggttcaaaa
    28921 tcgattgatt gtccccactc tgtcagacct aataccactc caaggaaaat ttggatcagt
    28981 ggagctggaa tcattggcaa aatgcggcta gctatgttcg ataaggtgat cgttactgca
    29041 aatacaataa ctaactcagc aaattccatc gtccatcccc tttatttttt attttgtgta
    29101 agcattttta aaaattgttc ttttttcttt aaaattttgg tttcgactac ttcaacctgt
    29161 gtttggttac cctctaattc acactgtaca cgttttgact ccaaacgaag cagatcatgt
    29221 ttcagacgtt ccaactgacg atacatcaat atatttcttt tacgcaactt acaaagtatt
    29281 tgacggcggt catccatcga aagggcgcca tagcgatcat gcaacagttt tttttgttgt
    29341 tcaaaactct ctctcatttt ccagatctcc tatacacaaa cttccatcat tatagcaaag
    29401 ttctttttgg atgaaaaata tttcattgtt tcatcgttta ttgctagtta gaaatttcca
    29461 taaatttttc aacgcctcat tctattccaa atagtatcag atatcaagta aaacttaaga
    29521 aagataaaag tttctgacaa aagaatgttt acttttccat tcctgccttt cttgttcttt
    29581 tatcacaaca aaaaaatggg gctgcgacaa aaatcttgtc acagtccctt attctgaata
    29641 aacggtgtgg aagagacagc ctatcagtag taataagaca catctctttc acagcttcat
    29701 ttttgcgtaa aaatcgattt attcgaaaaa ttccccgtat acatcttcta cacgttgatc
    29761 tggattgatc acgatataca agttacctgt tttttcgctg atttttgttg attgatattg
    29821 attgtctaat ccttctgttc ctttatctag atatgggaag tacacaagat caggtgtgcc
    29881 atttcggtaa aggatttcca ttcgctcgat atcttcgtat ttcaatgcgc gattaaacat
    29941 gcccatttcc agtccgccta ggttgatatc atgtgtcgca actgcgtccc cttcatggaa
    30001 gatttcgatt ttaaatccag cacacggatg gatttcaaca aattcactgc cattgattcg
    30061 tccaaaactt gttgtgattt gtttgatcca aagatcgccg atatgacggc ggttgatcgt
    30121 ccaggtttct ccatttctaa aataaaattt tagcgctgtc atttctttac tcattaaaaa
    30181 gactccttta tgatgtaatt tattcttgta ctacctcagt ttagcacaaa tttatgtaag
    30241 tggtcacatc ttatgttttt tcttctaatg acgtatctgc ccactttaag tagccaacaa
    30301 agctgagcag atacagtcta gtgtttttta aatcaatttt tctttcgata aaaaatccaa
    30361 aacctgtttt ttatcatttt ttattctttg ttctacgacg gctttttcag ctaattgcaa
    30421 agcttcacta acccacttac caggtttttt tccagtttct tctagcaaga ttttaccatc
    30481 tactgctaat tcgcttaatg acttgatagg taaacgatca taggattctc ctacggcatc
    30541 catctgaggt gtttcgtcaa aatagatcat caattcttct acttgcagtg catgtttttt
    30601 gcctaagaag tacaattcga atggttccaa agctccagtt tctcgttgtc gtagtccttg
    30661 gacaagtgct tgaacgtctt taatcatttg gttagaacac ttccacgatt tcaaaaagga
    30721 acgaatctca ttttctttta gacccagttg gctgatcaat aatgtccata cttggctctc
    30781 ttctttcaat gggacggatg gtaattcagc aaaacgtaaa agtgcttcgc cttcttcttt
    30841 caaactggga cagcaaatgt agcactctgt ttcaataaat gcatggattc ccgcggcccg
    30901 ttcatttccc aagagcatct tgatgaattc cacatttata cgttctacag atattttacc
    30961 taatagctcg tggttttctt tgatggcgta gaaggtttct tcctctaatt tgaaccctag
    31021 ttgactgaca aaacgcaacc cgcgcatcat tcgtaaggca tcttcatgga accgctcatg
    31081 aggattgcct acagctcgca agatctgttc ttctaaatct tgcagaccat cgaacaaatc
    31141 gatgatttct ccatcttctt tcaaagcaaa cgcattgatc gtaaaatctc ttcttttcaa
    31201 atcttctgcc aacgaacgaa cgaattcgac atgatctggt ctgcggtagt cctgataagt
    31261 tgattccgtc cgaaatgtgg tgatctcata ttgttcatca ttttctaata ccaacacagt
    31321 tccatgttcg atcccaatat ctatcgtttt tggaaaaagc tgtttgattt cttctggaaa
    31381 tgcgcttgtt gcgatatcca catcatggat tggctggttc agcaagatat cacgtacact
    31441 tccacctaca aaataagctt catatcctgc attctctaat tttttcagaa ctggaattgc
    31501 cttttggtat tccagaggta attgttttaa tttcattttt ccaacctttc ctgcgtgttt
    31561 cttgtactga gataaagact cagttgcatg gtgactgttt gacaagtccg tttcagagtc
    31621 ttcaaggcca ggaccacttc atcttgttta ctcgtcctta cgctcaaagc gattatggtc
    31681 tctttgattg aatttttcca tgtttttttc aaaaacttca gttaagtcga tattcaatga
    31741 attagccatg atcatcgtaa cgaataaaac atcaccaagt tcttctgcta ccgagttaac
    31801 tggttcagaa gcctttttgc ttttttctcc ataagtgtgg ttgacttctc ttgccaattc
    31861 acctacttct tcagttaatc gagccatctg agctaatgga gagaaatacc ccaccttgaa
    31921 ttgctggata tattcatcca cttcctgctg catactgtat aaagaacgct ttttatccat
    31981 ctttttccct ccaaaactat cttaccaaaa ctttaacgca aatcctagat aagagcagtt
    32041 gagaaaatcg aatttccatg ctacatttag aaaggaattt ctaaatggaa attctgtgaa
    32101 aatacataat tgaaagctgg aattcatatg gtcaaacgaa aaacagtaaa agaagttctt
    32161 tttatcatta taggaacaag tatttatgca tttggtcttg tttacttgaa catcgctaat
    32221 catttagcag aagggggcgt ctcagggatc accttgatct taagagcttt attcggaatt
    32281 gatccagctt atacgacttt attaatcaac atcccattga ttttactagg aggaaagatc
    32341 ctcggtaaac gttccttggc ctatacagtt ctaggtacac tttctttgtc attcttttta
    32401 tggatctggc aaagggttcc actagaaatc aatttacagc atgatctact gatcgtttct
    32461 ctacttgcgg gtttagttgc aggtgtagga agcgggatcg tctaccgcat gggtggaaca
    32521 acaggtggca gcgatattat tgctcggatt ttagaacaaa attacggcat cactatgggg
    32581 cgttccctat tggcatttga tatcatcgtc ttacttgctt cattaaccta tatcgacttg
    32641 aaacgtatga tgtatacgtt gattgtttcg tatgttttca gtcgtgtgat tgattcgatc
    32701 ttagatggcg gatattctgc aaaaggtcta cttgtcgtct ccaacaaaag cgaagagatt
    32761 gcaccactac tgatgaccgg tctgcaaaga ggtgtgactt ttctttctgg agaaggcgca
    32821 ttctctggta attcaaaaaa aatcatctat atggtcgtta gctctagtga attaactgaa
    32881 gctaagagga tcgtccacga gattgacgaa aaagctttcc tttcaatcat caatgtgcat
    32941 gaagtggaag ggcaaggctt tacttatttg aagccacaga caagattact gaaaaaacta
    33001 taagaaaaaa gacaaagata ggctatgagg aaagattc
//
LOCUS       DAPBCF010000025        32690 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.025, whole genome shotgun sequence.
ACCESSION   DAPBCF010000025 DAPBCF010000000
VERSION     DAPBCF010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32690
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.025"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            189..419
                     /locus_tag="RD508_001514"
     CDS             189..419
                     /locus_tag="RD508_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HDT7736123.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            516..1817
                     /gene="murA"
                     /locus_tag="RD508_001515"
     CDS             516..1817
                     /gene="murA"
                     /locus_tag="RD508_001515"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDT7736124.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1830..2006
                     /locus_tag="RD508_001516"
     CDS             1830..2006
                     /locus_tag="RD508_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDT7736125.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2141..2437
                     /gene="yidD"
                     /locus_tag="RD508_001517"
     CDS             2141..2437
                     /gene="yidD"
                     /locus_tag="RD508_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDT7736126.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2622..3089
                     /locus_tag="RD508_001518"
     CDS             2622..3089
                     /locus_tag="RD508_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7736127.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3174..4058
                     /locus_tag="RD508_001519"
     CDS             3174..4058
                     /locus_tag="RD508_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7736128.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4172..4408
                     /locus_tag="RD508_001520"
     CDS             4172..4408
                     /locus_tag="RD508_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HDT7736129.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4496..4576
                     /locus_tag="RD508_001521"
     tRNA            4496..4576
                     /locus_tag="RD508_001521"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4530..4532,aa:Tyr,seq:gta)
     gene            4583..4654
                     /locus_tag="RD508_001522"
     tRNA            4583..4654
                     /locus_tag="RD508_001522"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4615..4617,aa:Gln,seq:ttg)
     gene            4779..4949
                     /locus_tag="RD508_001523"
     CDS             4779..4949
                     /locus_tag="RD508_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736130.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            5169..5876
                     /locus_tag="RD508_001524"
     CDS             5169..5876
                     /locus_tag="RD508_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7736131.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5935..6579)
                     /locus_tag="RD508_001525"
     CDS             complement(5935..6579)
                     /locus_tag="RD508_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDT7736132.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6705..6992
                     /locus_tag="RD508_001526"
     CDS             6705..6992
                     /locus_tag="RD508_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736133.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7100..7420
                     /locus_tag="RD508_001527"
     CDS             7100..7420
                     /locus_tag="RD508_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7736134.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7501..8814
                     /locus_tag="RD508_001528"
     CDS             7501..8814
                     /locus_tag="RD508_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDT7736135.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLSNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKIL"
     gene            8811..9530
                     /locus_tag="RD508_001529"
     CDS             8811..9530
                     /locus_tag="RD508_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HDT7736136.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9658..10209
                     /gene="raiA"
                     /locus_tag="RD508_001530"
     CDS             9658..10209
                     /gene="raiA"
                     /locus_tag="RD508_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDT7736137.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10431..12965
                     /gene="secA"
                     /locus_tag="RD508_001531"
     CDS             10431..12965
                     /gene="secA"
                     /locus_tag="RD508_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDT7736138.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            13091..14192
                     /gene="prfB"
                     /locus_tag="RD508_001532"
     CDS             join(13091..13162,13164..14192)
                     /gene="prfB"
                     /locus_tag="RD508_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDT7736139.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14297..14983
                     /gene="ftsE"
                     /locus_tag="RD508_001533"
     CDS             14297..14983
                     /gene="ftsE"
                     /locus_tag="RD508_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HDT7736140.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14967..15860
                     /locus_tag="RD508_001534"
     CDS             14967..15860
                     /locus_tag="RD508_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7736141.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            16012..17460
                     /gene="cls"
                     /locus_tag="RD508_001535"
     CDS             16012..17460
                     /gene="cls"
                     /locus_tag="RD508_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDT7736142.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEIAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYILQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17797..18654
                     /locus_tag="RD508_001536"
     CDS             17797..18654
                     /locus_tag="RD508_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HDT7736143.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18769..19689
                     /gene="pstC"
                     /locus_tag="RD508_001537"
     CDS             18769..19689
                     /gene="pstC"
                     /locus_tag="RD508_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDT7736144.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19689..20573
                     /gene="pstA"
                     /locus_tag="RD508_001538"
     CDS             19689..20573
                     /gene="pstA"
                     /locus_tag="RD508_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDT7736145.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20588..21394
                     /gene="pstB"
                     /locus_tag="RD508_001539"
     CDS             20588..21394
                     /gene="pstB"
                     /locus_tag="RD508_001539"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDT7736146.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21410..22168
                     /locus_tag="RD508_001540"
     CDS             21410..22168
                     /locus_tag="RD508_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDT7736147.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22181..22858
                     /gene="phoU"
                     /locus_tag="RD508_001541"
     CDS             22181..22858
                     /gene="phoU"
                     /locus_tag="RD508_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDT7736148.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23095..24126
                     /locus_tag="RD508_001542"
     CDS             23095..24126
                     /locus_tag="RD508_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HDT7736149.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTNQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKHGLFALGSLIINIVLLLLLLLIFTKIEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNLWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            24123..24890
                     /locus_tag="RD508_001543"
     CDS             24123..24890
                     /locus_tag="RD508_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HDT7736150.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTTIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            24990..26558
                     /gene="liaX"
                     /locus_tag="RD508_001544"
     CDS             24990..26558
                     /gene="liaX"
                     /locus_tag="RD508_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HDT7736151.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26855..27175
                     /locus_tag="RD508_001545"
     CDS             26855..27175
                     /locus_tag="RD508_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HDT7736152.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            27175..27525
                     /locus_tag="RD508_001546"
     CDS             27175..27525
                     /locus_tag="RD508_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDT7736153.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            27692..28630
                     /locus_tag="RD508_001547"
     CDS             27692..28630
                     /locus_tag="RD508_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HDT7736154.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28645..29475
                     /locus_tag="RD508_001548"
     CDS             28645..29475
                     /locus_tag="RD508_001548"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDT7736155.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            29519..30544
                     /locus_tag="RD508_001549"
     CDS             29519..30544
                     /locus_tag="RD508_001549"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDT7736156.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHCLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPVEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30559..31497
                     /gene="galU"
                     /locus_tag="RD508_001550"
     CDS             30559..31497
                     /gene="galU"
                     /locus_tag="RD508_001550"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDT7736157.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            31622..32062
                     /locus_tag="RD508_001551"
     CDS             31622..32062
                     /locus_tag="RD508_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HDT7736158.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            32065..32667
                     /locus_tag="RD508_001552"
     CDS             32065..32667
                     /locus_tag="RD508_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDT7736159.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIIIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
BASE COUNT        10853 a         5543 c         7087 g         9207 t
ORIGIN      
        1 atttggaata agggactgcg acaagacttt tgtctcagtc cctttttttg catattttta
       61 gcatttattt cctaaaaaat gtaaggggat tcctatattt ttaagtatac ttgtttttcc
      121 ttttatacat tttatggtat tatcatttta ttagttatta taaaacaatc gttagaaagg
      181 acgtcattat gcaagtatac ggaattgatg cggtgcttcg aatcgtgagt catttggcgt
      241 ttatctactt agccttctgg tctttacgtt cgttacgcat tgaaactttt ttcagaccaa
      301 tgcataatac gcaaattaga atggcaatcg tacttttttc aattttttta gggtacactg
      361 caagtaattt tttcttagaa gttatcgctt tatgccgaaa tcttttcgtt agcctgtaaa
      421 ttttaaaaaa aggtactatt ttaaaagcaa ggatgttata atagaaaaga ttttgagtaa
      481 gtgtatgctc attggaattt tttggaggga acaacatgga agagatcatc gtaagaggtg
      541 gcaatcaatt aaatggaaca gtaagaattg aaggagctaa aaatgctgtt ttgcctattt
      601 tagctgctag tttgttagca gaagaaggta ttacgacatt agacaacgtt ccgattcttt
      661 ctgatgtctt cactatgaat caagtgattc gtcacttaaa cgtagatgta gattttgatg
      721 aacaaaagaa tcaagtaaca atcgacgctt caagacaatt agaaatcgaa gcgccttatg
      781 agtatgttag tcaaatgcgt gcttcaatcg ttgtgatggg tccgctactt gccagaaatg
      841 gacatgcaaa agtagctatg cctggtggat gtgcgattgg taaacgacca atcgatttgc
      901 atttaaaagg atttcaagct ttaggagcaa aaattattca aaaaaacggc tatatcgaag
      961 caattgcgga tgaattgatc ggtaacacga tttatttaga tttccctagt gtaggtgcta
     1021 ctcaaaatat catgatggct gccgtaaaag caaaaggaac aaccatcatt gaaaacgtag
     1081 ctcgcgaacc agaaatcgtt gatttagcaa acattttgaa taaaatgggc gctcaagtct
     1141 atggagctgg tactgaaaca atgcgtattg aaggcgtgga tcatttacat gcagtcaacc
     1201 actcaatcgt acaagatcgt atcgaagcag gtacctttat ggttgctgct gcaatgacac
     1261 aaggcaatgt gctgattgca gatgctatct ctgaacataa ccgcccattg atttctaaat
     1321 tgatcgaaat gggtgcagaa atcattgaag aagaaggcgg agtccgtgtc atcggaccaa
     1381 aacatatctt acctacagat gtaaaaacga tgcctcatcc tggtttccct acagatatgc
     1441 aagctcaaat gacagctatc caattagttg cagaaggtac aagtgtagtg actgaaacag
     1501 tgtttgaaaa tcgtttccaa catttagaag agatgcgccg tatgaacgct catgtcaaaa
     1561 tcgacggaaa tgtagcaatc atggatggaa accatgaatt gcaaggtgca gaagtatatg
     1621 caacagactt gcgggcagca gcagcattag ttttagctgg cttgaaagca aatggaatca
     1681 cacgtgtgcg taacttgaat tatctagacc gtggatatta taatttccat atcaaactac
     1741 agcaattagg tgcagacgtt gaacgtgtag acatggatca aacttctgct gaaaaaacag
     1801 cacaaacgat tgcttaagga agtggctgaa tgagtaacca acgatatatc ttattaactt
     1861 tgataaagat tttaatggtg atcttattgc ttatccttct ttttgtggcc ggaacgatga
     1921 tcggatatgg tgtcatcggt ggcggcaatc catttaaagt atttcagcca agtttgtgga
     1981 ttcatattcg agactttttt cattgataaa taagaatcac agtggttcta gtcgatatga
     2041 agtgagccat gaagcagaac atgataaaag aaaacagaag ggaacgttga cgttagtcgc
     2101 gatccctttt tttagtaaaa gaaaagaagg aatctaattg atgaagaaga tattgattta
     2161 tttagttaga ggatatcagc gctttatttc gcctgcattt ccacctagct gccgttatta
     2221 cccaacctgt tccaattata tgataaaagc aattcaaacc catggcgcgc taaaagggac
     2281 ggtaatgggg actgcacgga tcttacgctg tcatcctttt gtcaaaggcg gtatcgatta
     2341 tgtaccattg acattccgat taacgcgaaa taagaaagat aaaaaagaac cagattataa
     2401 aaaggttgtg aaaaatacgg gtagcactga gcgataaaga aacaatttgg aaaatagctt
     2461 cttatatttt gcaaaattgt gagttattgc cgaagtgttg gattttgaac accgtcaaaa
     2521 aaaaggttgt gaaaaatacg gctagcactg agcgataaag aaaaagagga aatttattgt
     2581 caaagtaaca actccgcaac tacttatatg ggggacaaaa aatgatcgaa gaactaaaca
     2641 agaaagattt accatggtcc ttgttattag atgcagatcc tgataaagaa aaagttcaag
     2701 tatatgtttc cagagggagt ggctggatat ggaaagaaaa agaaaaaaca ataggtgtac
     2761 tgatctatgt ggcaagggaa aaagaatacg aaatcgtcaa tgtagcagta accccaacgt
     2821 atcaaggaaa ggggattggc ggaaaattac ttgagacagc ttttcagaag ctttcacaac
     2881 tcgcttccag tcaaactcag atcatcatac gaaccggcag tactagcagt gcggcgttac
     2941 atctctatca aaaaatgggc tatgtggaga ttggtcgagt caaagactat tttatccatc
     3001 attactctga gcccattttt gaaaatggag atcaattaag ggatcaagtg attttagcaa
     3061 ttcacttacc taaaaatagc tttaactaat aaaatttcaa ttcaagaaaa tgctttcaaa
     3121 tgctaaatag atacattaca atagctttag caaacaaaaa ggagaatatt tttatgggaa
     3181 tattagtttt tgattttggt ggatcggctg tcaaatatgg ttgttgggat ggcaaagaga
     3241 ttaaaggtaa gggacaattt gcaacgcctg aatcttggga agaaatgaaa gcgcaattat
     3301 ttcaagttta taaaaaaata ctcgtttctt ttgaagtcga aggaattgga atcagctctc
     3361 ctggagtagt gaataatgag aaacaggtga ttgagggaat cagtgcgatt ccttatattc
     3421 atggatttaa tattttccga gatttggaaa ctctgtttca acttccagta acgattgaaa
     3481 atgacgccaa ctgtgccgga atggctgaat tttatgaagg tgctgcccgc gattatcaag
     3541 atgttgcttt tgttgtggca ggaactggga ttggcggggc gttgttcacg aaaggacaaa
     3601 tcaataaagg ggcacatctt tacggtggag aatttgggtt gatgttctta aatggcgata
     3661 agacattcag taaacttggt acagcggtac agatggcttg gcgttattgt gaacgcaaag
     3721 gtctcgataa aaatgcttat accggaaaag atgtctttga attagcagaa actggagatg
     3781 caatagcaaa agaagaagtt gagagttttt atacgtatct tacaaaggga ttattcagta
     3841 ttcaattttc gtttgatcca gaagtgatcg tattaggcgg cggggtttct gcaaaagaag
     3901 ggctcattga tgagatcaaa agccgaatga agaagctgac agaacaattc gatctgcatg
     3961 atttcgaacc gcagatttta ttatgtgaat acagaaacga tgctaatctt gtaggtgcag
     4021 cagcaaacta tctcgctgta cgtcaagggg agaattaaga gctttagaga aggtgcagct
     4081 tgcataaaag aagtgaatga aatgaatagg agatttttac ctaaggaatg ttttatttgc
     4141 tgcagtatga taaaatatct gagaggtgaa aatgatgtca aaaaaaaata aagatattga
     4201 agtgcgtata gaagaagtga aaaaagatat caaaggtaag aattatgaag tcactcagtt
     4261 atttataggg aaaaaaatga ttggtgagat cttagcctat ggaccaaaag aatatgaaat
     4321 tttctttggt gaagaagatt ttggaaaaga aaaaagtctt gaaaatgcga tagaaacagt
     4381 gattcgacac tggaatctgc acgaataaaa aaatatcaaa aaaactttca ataaagggtt
     4441 gcaaaaatct ggaaaattag gtattataac taagtcaggt tgatacaaac ctttcggagg
     4501 agtagcgaag tggctaaacg cgacggactg taaatccgtt ccttagggtt cagtggttcg
     4561 aatccactct cctccatttc attggggtat agccaagcgg taaggcaagg gactttgact
     4621 ccctcatgcg ttggttcgaa tccagctacc ccagtatacc acaatcgtaa gctctcgtta
     4681 gttcgagagc tctttttttt gctttgctac cttgttcctt gaagattctg ctgatttaag
     4741 atagagttaa gttaactaca agaattggag ggatccacat gaaatggaaa gaaaaagtag
     4801 acgaagcagc tgaaaagtta tatgatttgg tcaaatcaga aaaatacaat attgaagtga
     4861 atattccgaa aaaaggcgga aaagcggtcc gggtaaaatc aaaacgccca acgaatcata
     4921 caaaaaaatg gatggctaaa aaccgctaat aataacaaaa gatccataag tcggcatttt
     4981 catcgatttt agggtctttt gttattttct aggttggaca tatctaaaaa attgtttctg
     5041 acaataggag taggaagaac gatgtgtgtc taaatcctct gttgatggat agaaaccttt
     5101 atctttttca gttgtgaatc aggtatatac cagttataat agaagaaacg aaaggacggg
     5161 tgtacgttat gtcgaatcaa ttacctgtat atatacagat tcatgaccaa ttaaaaaatg
     5221 aaatcgaaca aggtatatgg aaagtcggag accgtcttcc ttcagaaaga gaattagcag
     5281 tgaaattcaa tgtcagccgt atgacgttga gacaagcaat tcaaaacttg gcagatgaag
     5341 gaatcttaga aagaaagatc ggttcgggta catatgttgc acgagaaaaa gtacaagaaa
     5401 aaatgtctgg tgcaacaagt tttacagaaa ttatggaatc acaaaatcga gtaccgtcta
     5461 gtcggacaat ctcttatttc ttgacttcgc caagctcaag tgaaatggaa aaactaaact
     5521 tgagtaaaga tgacacgatc ttgcgaatgg aacgtattcg tttcgcagat gatgtcccta
     5581 tttgttttga agttgccagt gtgccacaaa agctgatcga tggctacagc aaagcagaga
     5641 ttactgaatc gttgtatcgc acgctagaag aaaaaggcgg gaaaaagatc ggtccagcga
     5701 atcaaacgat tactgctgtg ttggcttctg agaaaattgc tgactattta gaggtaaaac
     5761 gaggagatgc agttcttcgt ttgcgccaga tttcttattt tgaagacggt acgccgtttg
     5821 agtatgtgcg tacgcaatac gtaggaaatc gttttgagtt ttatttggaa aaataaaaaa
     5881 caggtgatcc ctgattccgt attagaaata aaagagaatc agaatcacct gtttttatat
     5941 atgatcagtt accagttgct cgtgataaga aacaggaccc tcttcaaatt ggacttgtcc
     6001 gttcagcagc tcaatgatgg attctttaaa gtggtcagca cttttttcat ctacagcaca
     6061 gatgacgcta acttgatcag tatattggat ttcttttata aaaaaatgtt ggagttcaag
     6121 ataattctgt aattttccta gttgcggata cgtgatcatc acagagatct cctgttgcaa
     6181 ggtaccttct acgattccaa tgtcagacaa tgcttgagag accgcatgag tgtatgctcg
     6241 tattaatccg cctgtgccga gtttcgttcc tccaaaatat cgagtgacta ctgcagctac
     6301 attgatcagt tgattttttt tgaggacttc caacatcggt atgcccgccg ttccacttgg
     6361 ttctccatca tcgctgcttc gctggatttc atttttttct ccaatgatga aggcgctgca
     6421 gttatggttc gctttccaat gttctttttt tatttcttga atgaaacttt ttgcttcgtc
     6481 ctctgattct attcgtctaa gagaacagat aaagcgtgat tttttgatct cgatctcact
     6541 ttgtccattt tcttttattg tacgatagcg ctcgatcatc ttgtcacctc ttttttcatt
     6601 ttctttattc agtataaata aagttctagg ttgtttcaac actgtaacgg ttgcgcaatt
     6661 gctgtagtat gcgataataa agacaaaggc aggtggatct ggggatgcag gaacgaatga
     6721 aaaagtacga tgcaattacg cattatttga agaacaatgg cggctctcaa gtaacgttga
     6781 cctttaccca atttgacgaa ctgctgtttc ccagtaacgg acttcccaaa acagcaaggg
     6841 aaagtacaga ttggtgggca aatgattata aacaccctga aaaaggtgcc tatggctgga
     6901 taaatgcagg ctatgaagta gttgtcatca atttggacaa agaatatgtc gtgttcaata
     6961 aattagtgaa atctagttgg ctatttgatt aaataaaccg cgtttagaaa acgttgacaa
     7021 atttctttct ttttatataa tagagtaaca gacgcgaaga aaatgtttgc gtagtttgtt
     7081 ttaaaaagga gagaaaagta tggctaaaaa aacaatcatg cttgtatgtt cggctggtat
     7141 gagcacaagt ttactagtaa caaaaatgca aaaagctgct gaagcaaaag gaatcgactc
     7201 tgatattttc gctgtgtccg cttctgacgc agataacaat cttgcaaata aagacgtgga
     7261 tgtgttgtta ttaggcccac aagttcgctt tatgaaagct gattttgaga aacgtctgga
     7321 accaaaaggc attcctttag atgtcatcaa tatggctgat tatggtatga tgaatggcga
     7381 aaaagtgtta gatcaagcaa tcacgctcat aggtgaataa atagaacagt ataactatcg
     7441 aacaagcgat ccaaaaaata gatcgcttgt tttttcgtat atttttttag ggcgaataat
     7501 atgaatcatt tttggggtag aaggcttctg acgagagata ttaaagcaat agactgtgag
     7561 gaggtaaatt taccaaatta tgagaagatc gcagcagtgg aacgtttgag caactggatt
     7621 ctttgtcatc gctgtggaat gagaacgtcc gtcattgatg gacagcttgc agattacggt
     7681 tatttttgta cacattgtct atatttaggg cgatgcgaca ctcaacaaga tttatatttg
     7741 tttgatcagc ctgaagcaaa acctcgagaa gtcgtctttt tttggacagg acagcttact
     7801 gaaaaacaaa cggaaatctc aaagagaata ctttgccatt cagaaaaaag acatcatctt
     7861 atttgggctg taacaggtgc agggaaaaca gagatgcttt atcctatttt agtggaaact
     7921 ttaaaagctg gaggaagagt agcgatttgt acaccgcgag tcgatgtttg taatgaattg
     7981 tttttacgct atcgttatgt ttttccagaa gaaaaaatca cgttgctcca tgggaataca
     8041 gcaacggctt atacctttac ttcttttgtt atctgtacga ttcatcagct ataccgtttt
     8101 tatcggtcct ttgatttaat agtgatcgat gagatcgatg cgtttcctta taacggggat
     8161 gcaggattag ctcatgctgt gcaaacagcg attaaaccag acggacgatt catctactta
     8221 agtgccacac ctgataaaaa gttactaaag gagatcaagc agacgtttga catccacaaa
     8281 cttgctttac gctttcatcg gcgtttgctt cctgaacccg tcttggtttt catgaataat
     8341 tggcgacaaa aatgcaagaa caagaagaag ataaaatctt tggtgcggat cattcatcaa
     8401 ttaattaaag aaaaccatat ccttttattt tgtccaagta tcacgatgat gcatcgtttg
     8461 aaagccacac ttcaagaggc tcttccgaga tatgagatca cagatgtttc ttcaagagac
     8521 aatcagcggg cggaaaaagt ccagaaaatg cgagaagcaa aatatgacat actgttaacc
     8581 acgatgatcc ttgaacgtgg agtcacattt gaaagaatat ccgttatcgt tttaggagcg
     8641 gatcatccgg tttttactaa atcttctttg gtacaaatcg caggaagagc cgatcgtaaa
     8701 gggccttata cgaacagtca agtatatttt ttctatgaag aaaaaactgc agctattcga
     8761 aaagcttgtc aggaaatcaa agaaatgaat gaagaaggga agaagatact gtgaggtgca
     8821 gttgctgcag taaagatatc gtccaaaatt taacattcag cgagattatt ggtgtttcga
     8881 aatacagatt acctcagact tgttcagttt gtcgcgcaca atttcattta ttggaaacaa
     8941 gaggctgttc tggctgtcaa aaaccaatcc atttcaatct agagagtacg aaaaagaaag
     9001 taaattctat ccccgtttac tgcagtgact gtcaagaatg gaagaagaaa tatccgacct
     9061 atgattttca gcaccgtgcc ttttttgtgt acgatgaaaa tatgaaggcc tggctcaatc
     9121 aatacaagtt tatgggagat atccgactag caggcacctt tgcatataaa tggacgcaga
     9181 taaaaaaaga atacccgaca tacatctatt gtccaatacc tttatctgaa aaaaggcgaa
     9241 cagaaagagg attcaatcaa gtaagcgaga tgttgaaagc agcaagaatt ccttttcaga
     9301 tgctactcaa aagagagaag catctgctgg ctcaagcaaa aaacacgcga aaggaaagat
     9361 tggagatgcc tcaacctttt gaacttgcag tcaccttttc taagatacaa aataaaaaaa
     9421 tattgattat tgatgatgtc tatacaacag gacagactct tttccacgca gcagattgtt
     9481 tgcagatcgc acagccgaaa atcatccgaa ctatttcttt ggcgagatga attagatgtg
     9541 gaaatttgat agcgatttaa tttgcaaata acctagagtt cgatataata gaattaagaa
     9601 gagggaaaga gtggtccttc tccttcttga ttgtggtaga cgaaaggggt aatttttatg
     9661 tttagatata atgtacgcgg cgaaaatatc gaagtaactg aagcgattcg cgactacgtt
     9721 gagaaaaaag taggcaaact agaacgctat ttcagtgacg cacccgatgc aacggcgcat
     9781 gtgaacttaa aagtttatac agaaaaaaca gcaaaagtgg aagtaacgat cccattacct
     9841 tatcttgtat tacgtgccga agaaacttct ccagatttat acgcaagtat cgatttggtt
     9901 gttgacaaat tggaacgcca aatccgcaaa ttcaaaacaa aaattaatcg taaatcccgt
     9961 gaaacgggca tgaatactgc aaatgctgct gctttattca atgaagagga cgaaaacgaa
    10021 aatgattctg aattagatat cgtacgtacg aaacgccttt cattgaaacc aatggatagt
    10081 gaagaagcag tcttgcaaat gaacatgctg ggacataact tctttatttt tgaagatgca
    10141 gaaacaaatg gtacaagtat cgtttaccgc cgtaaagatg gaaaatacgg actgattgaa
    10201 acagactgat cagccttact taaataacaa cgaaaacttg cagcagctac tgacagctgc
    10261 cgcaagtttt tttgagtttc ctcctctttt agatgaaata tgaataaatt atgaagttct
    10321 tactttaata cgcttaagat atttcaatta tctataacta atgataaaat gaaaagtaaa
    10381 gtctacatag tctggataat acacagaagg aaaaggagat tacacaacgc atggccaatt
    10441 tgattcgttc acttatcgaa aacgataaga aagaactaaa acgtttagat agcattgcaa
    10501 aaaaagttga agcatacgct gaccaaatgg cagcattaac tgatgaacaa ttacaggcaa
    10561 aaactgctga attcaagggc agataccaaa aaggagaaac attagatcaa ttacttccgg
    10621 aagcttttgc agtcgtccga gaagcagcaa aacgtgtatt aggtttatat ccataccacg
    10681 tacaattgat gggtggaatc gtgcttcacg atggaaatat ccctgaaatg cgtactggtg
    10741 aaggtaaaac cttgaccgca acgatgccag tatatctaaa tgctctgact ggcgaagggg
    10801 tacacgtagt taccgtcaat gaatatttag caacccgtga ctcgacggaa atgggcgaac
    10861 tttataattt cttaggatta acagtggggt tgaatatcaa ctcaaaatct tcggatgaaa
    10921 aacgcgaggc ttataattgt gatatcactt atagtacgaa taatgaatta ggatttgact
    10981 acttgagaga caatatggtc gtttaccgcc atcaaatggt acaacgtccg ctgaattatg
    11041 ccattgtcga tgaagttgac tcaatcttga ttgatgaagc gagaacgccg ctgatcattt
    11101 cagggcaagc agaaaaatcc acagctttat atacaagagc agacaacttc gtgaaacgtt
    11161 tgaaagaaga agaagattat aaaatcgatg tacaatcaaa aacaatcagt ttaaccgaag
    11221 cagggatcga aaaagcagaa gaaacattcg gtttggataa cttatacgac attgaaaata
    11281 ctgcattgac ccatcacttg gatcaagcat tgagagccaa ctatatcatg cttttagata
    11341 tcgattatgt tgtccaagac ggaaaagtac tgattgttga ccagttcact ggtcggatca
    11401 tggatggacg ccgttattca gatggacttc accaagcaat cgaagctaaa gaaggcgtag
    11461 agatcgaaga cgaaacgaaa accatggcga cgatcacttt ccagaactat ttccgtatgt
    11521 acaagaaact tgcgggaatg actggtacag ctaaaacaga agaagaagaa ttcagagaaa
    11581 tttataacat ccaagtatac cagattccga caaatcgtcc ggttatccgt gatgatcgtc
    11641 cagatttgct ttacccaaca ttacaaagca agttccacgc tgtcgtgcaa gatatcaaag
    11701 atcgctaccg caaaggtcaa cctgtgttag tcggaactgt tgcggttgaa acatctgagt
    11761 tattatcaga tatgctgaat caagaacgta ttcctcatga agtgctgaat gcgaaaaatc
    11821 actttaaaga agcagagatc atcatgaatg ctggtcaaaa aggtgctgtg acgattgcta
    11881 ccaacatggc tggtcgggga acagatatca agttaggact tggggtaaga gaacttggtg
    11941 gtctagcagt tatcgggaca gaacgacatg aatctcgtcg tatcgataac cagcttcgag
    12001 gacgtgcagg acgtcaagga gaccctggta tgtcacagtt ctacttgtca ttggaagatg
    12061 atttgatgaa acgattcggt tcagaacgaa tcaaagcttt cttagatcgg atgaagatcg
    12121 gtgaggaaga tgctgttatc caaagcaaga tgctgacgaa acaagtagaa tctgcacaaa
    12181 aacgtgtaga aggaaataac tatgacacac gtaaaaacgt cttacaatac gatgatgtga
    12241 tgcgtgaaca acgtgaagta atctataaac agcgacaaga agtaatcatg gaagaaaaaa
    12301 gcttatccaa gccactaatg aacatggtca aacggacaat cagtcgtgta gtagatgcgc
    12361 atacacaatt agagaaagaa aattggaatt tggaaagtat catcgatttt gccggcagta
    12421 ctcttgtcca tgaagatagt attactcttg cagatatcga aggaaaaaca gctcaggaga
    12481 tcaaagagta tctaaacgaa cgagcacaag aagtatttaa taccaaagcg gctcaactaa
    12541 atggtccaga gcaactgttg gaatttgaaa aagtcgtgat cttgcgtgtt gtggactcta
    12601 aatggacaga ccatattgac gcaatggatc aattacgtca gtcaatcggc ttacgtgctt
    12661 atggacagaa caatccatta gtcgaatatc aaacagaagg ctataagatg tttgaagata
    12721 tggtaggcgc catcgagtat gaagtcactc gaatctttat gaaagctgag atccgtcaaa
    12781 acgtacagcg tgaacaggtt tctcaaggaa cagcttctca ctcagaagac ggagatgcca
    12841 aagaaaatag taatactagc gcgaaaaaac agccaatcca tgtgaacaag gtcggaagaa
    12901 atgatccttg tccttgtgga agcgggaaaa aatataagaa ctgtcatgga aaaaatgcaa
    12961 actaatttct gacagcagga ttggtgagac aaattctttt tttaagaatt cgtctcacct
    13021 tctttctgtt atttgctgat tctgttagac tagatataat gaaaaaagta tagtgaaaga
    13081 aggaaaaaac atggaaatat ccgaaattcg aaatctcctg acagaaatgc aggaaaaggt
    13141 cacaagtttc aggaggtctc tttgacttag atcagctgga agaagacatc gcggaagcag
    13201 aagcaaaaat ggctgaacct ggtttttggg atgacagcga agccgcacaa aaagtgatca
    13261 gtgaaaataa cgctaataaa gaaacctatg accaattcca ttctcttgcc gaagaactag
    13321 aagaaatcga attgatggtg gagatgctgc aagaagaacc tgatgcagca atgcaagaag
    13381 aagcagaaac acgtatcaat gcattagatg aaaaaatgaa gacgtatgaa ttatctatgc
    13441 tgttagacgg accttatgat cgaaacaatg cgatcgtcga attgcatcca ggggctggcg
    13501 gaacggagtc ccaagactgg ggcagcatgc ttttacgtat gtatacacgt tgggcagagc
    13561 agcatggcta tcaagtagaa acactagatt atcaagcagg tgatgaagca gggatcaaga
    13621 gtgtgaccct gctgattaaa ggacataacg cttttggtta tctaaaatca gaaaaaggtg
    13681 ttcatcgcct tgtacggatt tcgccttttg actcagcgaa acgacgtcat acttcttttt
    13741 gttcggtaga tgtgatgcca gagcttgatg aaacgatcga tatagaaatc aatccagatg
    13801 atttgaaaat cgatacgtac cgagcaagtg gtgcaggtgg tcagcacatc aataaaacag
    13861 aatctgctgt acggatcact cacttgccta caggaacagt agtagctagt caggcacaac
    13921 gctcacaatt gaaaaaccgt gagcaagcga tggggatgtt aaaagctaag ctttatcaat
    13981 tagaagtgga aaagaaagaa caagaagcag ctgcacttcg aggagaacaa aaagaaatcg
    14041 gctggggttc acagatccgt tcttatgttt tccatcccta ttctatggta aaagaccatc
    14101 ggacaaacgt agagacagga aatgtccaag cagttatgga cggtgacctt gatttattta
    14161 ttgacggcta tttaaaaatg catctacaat aagaacccat tgttaaattg aaataaaatt
    14221 gtaagatttt gcaagcatgt tgaaacattg ccatgctata atagctaaag actgaaaaag
    14281 atatggagag aacgccatga ttgaaatgaa ggatgtaatg aagaagtact caaatggtac
    14341 gaccgctatc cgcaatctct cgattgtcat cgaacaagga gagtttgtct atgtggttgg
    14401 tccgtctgga gccggtaaat ctacattcat caaattgatg tatcgagaag aaaaagcttc
    14461 aaaaggaact ttgaacgtcg caggtcatga tctaatagca atcaaaaacc gcgaagttcc
    14521 ttatctacgc agagaaatcg gcgtggtgtt ccaagactat aaattattac caagaaaaac
    14581 agtatatgaa aatgttgcgt acgctatgca agttatcggc agaaaacctc gagatatcaa
    14641 aaaacgagta atggaagtgc tggaccttgt tggtttgaaa cacaaagttc gagtctttcc
    14701 tagcgaatta tccggtgggg aacagcaacg tgtctctatt gctcgggcaa tcgtgaatac
    14761 gcctaaagta cttatcgcgg atgaaccgac aggaaatctg gatccagaaa actcatggga
    14821 aatcatgaaa ttattagatc ggatcaatgc ccaaggaact actgtcgtga tggctacaca
    14881 taacagtacg atcgtaaata cgattcggca ccgagtaatt gctatcgaaa acggccgcat
    14941 tattcgagat caagcggaag gggaatatgg atacgatgat tagaaccttt ttccgccatt
    15001 tattagaaag tatcaagagt ttgaaacgta acggctggat gacagttgct tcagtcagtg
    15061 cggtaacgat cacgttgact ttagtcggtg tattcatggc agttatcatg aatgcaacta
    15121 aattagctca ggatatagaa ggaaacgttg atgtatctgt attcgtagat atcggtacaa
    15181 aagacgaaga gatgaaaaag ctagaaaaag aattgaatga cttagatcat gttaaaaaag
    15241 ttgaattttc aagtaaagaa caggaattga aaaaaatcca aaacgaaatg ggtgattcct
    15301 ggaaattgtt tgaaggtgac aataacccgt tatatgatgt gtatgtagta agtgctactg
    15361 atccttctta tacaaaacaa gtagcagaag aagcagcaga tttgaagaat gtttctcgtt
    15421 ctgattacgg tggagcttcc tcagatcgga ttttccaaat cgctggtgca gttcggacat
    15481 ggggattagt tgcagcggca ttgctgctgt tcgtagcgat gtttctcatt tcgaacacga
    15541 ttcggatcac gattttgtct agacagcgtg aaattcaaat catgcgttta gtcggtgcaa
    15601 aaaatggata tattcgctgg ccgtttttcc ttgaaggtgg ctggatcggt ctgatcggtg
    15661 cgattcttcc gattttgatc atcacatttg gttatgcatg gtttttccaa ttgatcaatc
    15721 catcattatt acgttcccat tattcattga ttcatccaca aaatatcgtt tggaaaatca
    15781 atcttttaat ggtcggcatt ggtgtgatca ttggttcact tggctcgatc atttctatga
    15841 gacgtttctt gaaattctaa taccacaata taaataaaat gagaaagttg gacagtttcg
    15901 ttccagcttt ctttttttat tggctaggag aatagaagga agcggctttt ttccctttac
    15961 tttaaaaaac aacttgggta ttcttaagtt ggtagaggaa gaggtgaagc cgtgaaaatt
    16021 atcgttgaca atttttttac gatccttttg attatgaata ttttgctttc ctttatcatc
    16081 gtttttcgag aaagaaagga aactgctcaa acatgggcat ggctgctcgt tttgatgttc
    16141 attccagttg taggatttat tttatatatt tttttaggaa gagggatttc caaagagaaa
    16201 atctttgatt tgaagatcca agggaaaatc ggtaagaacc tggaaattga agaagacaaa
    16261 caggcattga tgcgagggct ttatcctcat ccgcctactg gacaagtaga tgtgaaacaa
    16321 ttgatctata tgctcacggt atttgaaagt acgctctata cgactaaaaa tgaaatcact
    16381 ttatttacag atggtcgtga aaaattcgat gcgctgattg aagatatcaa gcaagcagaa
    16441 gaccatatcc acttccagta ttatatttat cgcagtgatg cattaggtga agaagttcga
    16501 gatgcattga cagaggcggc aagacgaggg gtaaaagtca gagtccttct tgatgcatgg
    16561 ggttccacac aagtttcttc cagctttttt cagaatttga aaaaagcagg cggagaaatc
    16621 gcatttttct ttcctctatt tgttccgtat attaatcctc ggatcaatta tcgcaatcat
    16681 cgtaaaatcg tagttattga tgggaaaatc ggatatacag gtgggttcaa tgttggaaat
    16741 gaatatctag gattggtaaa gaaatttggt tattggcgag acaatcattt gcgtatttac
    16801 ggagaagcgg tgtatatctt gcaaaaccgt tttttgatgg actggaattc tcagcataca
    16861 aaagaagtag gctattctcc caaatttttt ccgtccattc actctactgg tgatatagct
    16921 gttcaaatcg tgacaagcgg accagatacc gaacatgaac aaatcaaaat gacttatttg
    16981 aaaatgattt cgttagccaa acgggagata ttgatccaaa cgccttatta cataccggat
    17041 ggatcgattc atgaagcact gaagttggct cttctttcag gcgtaaaagt tcatatccaa
    17101 atacctaaca aaccagatca tcttctcgtt tactgggcaa cgtattcttt cgctgcagag
    17161 ctgatcgagt atggagcaag gatcgaaaca tatgagaatg gatttattca tgcaaagacg
    17221 atgattatcg atggtggcat tgtttcagtt ggctcagcaa atatcgatgt tcgttcattt
    17281 cgcttggact ttgaggtcaa tacactgatt tatgatgaac gaatggcttc acgtgtaaga
    17341 aaagcatttt ttgaagactc gaaaatttct acgcatctca caaaagaaat gtatgaaaac
    17401 cgaggaataa tcatcaagat gaaagaagga ttagcaagat tgatttcgcc gctcctttaa
    17461 aacacaaaaa ggacatgaga accatcaaca gatggagatc tcgtgtcctt ttctaacggg
    17521 gccatttctg agagtacgtc agaaatggag aaagcgtctc gcatgagcga aattaacttt
    17581 ggggtatctc ttgttttttg gggaaagcaa gaaataagct aatatatgct attaaaagag
    17641 acacatttca aagccagtat agcatagaaa cttttaatga gatagttttt tttacaatta
    17701 tgaggattta ttttgttatt taatgatttt gattcgtttt catcaagtaa tgaaaatgat
    17761 aaaataaaca tactttagga ttaaaggaga tttctaatga aaaaacttaa attattctta
    17821 ccaataatag gattagctat tcttttatca ggctgttcaa agtggattga tcgaggagaa
    17881 tccattacgg ctgttggctc ttctgcttta cagcctttag tagaaacagt tgctgaaact
    17941 taccagacag aaaatcctgg aaaattcatc aatgtacaag ggggcggaag cggaactggt
    18001 ttgtctcaag tacagtcagg agcagtcgac atcggaaact ctgatttgtt tgcggaagaa
    18061 aaatcgggga tcgatgcctc agcattagtc gatcatcgag tagcagttgt tgggatcact
    18121 cctattgtga acaaggatat tggcgtaaaa gacatcagta tggaaaacct gaaaaaacta
    18181 tttacaggcg agatcaaaaa ctggagtgaa gtcggtggaa aagatcagcc agtagttata
    18241 ttgaaccgtg cttcaggaag cggaacccgt agcacgtttg aaaaatgggt attggacgga
    18301 gaaacagctg ttcaggcaca agaacaagat tcaagcggaa tggtgcgcca gatcgttgcc
    18361 gacacacccg gtgcaatcag ctatgttgct ttttcttatg tttccgatga tgtagatacg
    18421 ttgaatgtta acggtgtaga accgacagat gaaaatgtga caacgaacaa atggacgatt
    18481 tgggcatatg agcatatgta cacaagagat catccaaaaa aactgacaaa agaattttta
    18541 gactatatct tatctgatga agtacaagat aacatcgttg gagaactagg ttatatccct
    18601 gtttctcata tgaaagtcga acgtgattgg caaggaaata tcgttaaaga gtaatcttta
    18661 cacaaaattt acaaacttag ctaaactttt acatgttatt aaaaccaaat tgatgttcaa
    18721 tttgtacact gagtgagtat gttaaacctg attaaggggg agtcatctgt ggaagatgtg
    18781 aaaaaagtat tattaacaaa atcaaaacgt tcaaaaatgg aacagcgtgg aaaattcatc
    18841 agttttttat gtatcgcgct gatcgtgttg gttgtattat ctatttttta ttttgtagct
    18901 agtaaaggat tggccacctt ttttactgat aagatcaatg tatttgattt tctgtttggt
    18961 acagattgga atccaagcca aatcggagca aatgggaaac caatggtagg ggcattgcct
    19021 atgatcacag gttcgtttat tgtgaccttt ttatctgcta ttgttgccac accatttgcc
    19081 attggtgcag cagtattcat gacggagatc tctcctaaaa acggaacgaa gatcttacag
    19141 ccggtcatcg agctgcttgt aggtattcct tctgtcgttt atggttttat cggtttatca
    19201 gttatcgtgc cttttgtcag aagtattttt ggcgggacag ggtttggtat cttagctggt
    19261 acatttgtgt tgttcgttat gatcttgccg actgtcacaa cgatgactgt tgatgcatta
    19321 aaggcagtac cacggcacta tcgggaagct tcattagcgc ttggtgccac aagatggcaa
    19381 acaatctaca aagtcgtgct acgagcagcc gtgcccggga ttttaacagc agtcgttttt
    19441 ggtatggctc gtgcgtttgg tgaagcctta gctatccaaa tggtcatcgg taatgcagca
    19501 ttgatgccaa caggacttac tactcctgct tctacattga cgtccatctt aacaatggga
    19561 atcggaaata caatcatggg aacagttgaa aataatgtgt tatggtcatt agcgctgatc
    19621 ttgctattga tgtcattatt ctttaatatc gtgatccgta tgattgggaa gaaaggagag
    19681 ctgaaataat gaacgcaaaa cgctcagata aaattgctac aggtgtttta tatgtagttt
    19741 cggggatcat cgtattgatt ttagcagctt tactacttta tatcttagtt cggggaatac
    19801 cgcacatttc atggtccttc ttgaccgaac cttccaaagc ctaccaagaa ggcggtggaa
    19861 tcgggatcca gctatttaac tcgatttatt tgcttttgat cacgatgatc atcagttttc
    19921 ctatttcttt aggtgcgggt atctatcttt cagaatatgc tggaaaaaac tggctgacag
    19981 atgtgattcg cacgtcgatt gaaatcttga gctcattgcc ttctgtcgtt gtcggtttat
    20041 tcggtttctt ggttttcgtt attcaattcc agtatggttt ctcgattatt tctggtgcat
    20101 tggctttgac tgtattcaac ttgcctcttt tgactagaac agttgaggag tctttacaag
    20161 cggtccatta cacacaacga gaagcaggat tggctttagg tttgtcacgc tgggaaacag
    20221 tgataaaagt ggtggttcca gaagcgacac cagggatttt gactggtgtg atcctaagtt
    20281 ctggaagaat ttttggtgaa gcagctgcat tgatctatac ggctggacaa agtgcacctg
    20341 cgttagattt tacgaactgg aatccattaa gtgtttcaag cccgatcagc attttccgtc
    20401 aagctgaaac attagctgtc catatttgga agatcaatac agaaggcacg atgcctgatg
    20461 gtgtttctgt ttcggctggc gcttctgccg tgttgatcat tgctgtttta ctgttcaact
    20521 tcggcgctcg tgcgattggc aaacgattat accgaaaaat gacttcagcc taaggagaag
    20581 aagcaaaatg aaaaaatata actggaatga aacaaatgtc atcaccatgc caaaagagaa
    20641 agaagtagca ctatatacgg atgatctaca tgtctggtat ggcgacaatg aagcaatcaa
    20701 aggagtggat ctggaatttg aaaaaaataa gatcactgca ctgattggtc cttccggctg
    20761 cggaaaatct acgtatcttc gttcgttgaa tcgaatgaat gatgggatcg ctaatacgaa
    20821 aatcactggg aaaatcatgt atcaaggcgt agatattaat gcgcctcaag tggatgttta
    20881 tgagatgcgc aaacggattg gcatggtttt tcaacgtcct aatccgttca gcaagtcgat
    20941 ttatgacaat attacatttg ctttgaaaca gcacggcgaa aaaaacaaaa agaaattaga
    21001 tgaaatcgtt gaaacaagct tgaaacaagc tgccttgtgg gaccaagtaa aagacagctt
    21061 ggacaaaagt gccttggctt tatctggcgg gcaacagcaa cgtttatgta ttgctcgtgc
    21121 gatcgcgatg aaacctgata tcttgctgct agacgagccg gcaagtgctt tggaccctat
    21181 ttcgacagga acggttgaag aaacacttgt aaacttgaaa gaagactata cgatcatcat
    21241 cgtgacgcat aacatgcaac aagcggctcg tatcagcgac tatactgcct ttttctatct
    21301 aggaaaagta atggaatatg acaaaactaa caagatattt accagaccaa aaattcaggc
    21361 aaccgaagat tatgtgtccg gtcattttgg ttaagacgga ggcctcaaca tgacaaaaga
    21421 aattatttca tctaaagatc ttcatctgta ttatggaaag aaagaagcac taaaagggat
    21481 cgatctaagt ttcaatcaag gggaaatcac tgcgatgatc ggtccttctg gttgcgggaa
    21541 atccacttat ctgcgttctt tgaaccggat gaatgacctg attccgaatg taacgatcac
    21601 cgggagtgtt ttatataaag acaaagacat ctatggtcca aaaacagatg ttgttgaact
    21661 aagaaaagaa atcggcatgg tattccagca gccaaaccca tttccttttt ctatctatga
    21721 aaatgtcatc tatggattga aattaaaagg ggaaaaagat aaaaaagtcc ttgatcaagt
    21781 agttgaagaa agcctgaagg cagcgtctgt ttgggatgat gtgaaagaca aattgcataa
    21841 aagtgcttta tctttatccg gtgggcagca gcagcgtgta tgtatcgcac gtgttttggc
    21901 agttaatccg gaaatcatct tattggatga accaacaagt gcgcttgatc ctgtttctac
    21961 tgggaaaatc gaaagtatgc tgttagaatt aagagagcgg tatacgatga tcatcgtgac
    22021 ccataatatg tctcaagctt cacgtatttc agataagacg gcattctttt tagatggtca
    22081 cttgatcgaa tacaatgata cgaagaagat attcatgaat ccagaaaaac aagagacaga
    22141 agattatatt tcaggtcgat ttggataagg aggaaacgga atgctacgta cacaatttga
    22201 agaagaattg ctgaatctcc ataatcagtt ctacgaaatg gggatgatgg tgagcagcgc
    22261 cgtgcacaag tcagttcgtg catacatcaa acacgataaa atcttagccc aagaagttat
    22321 cgaaaacgat ataaatatca ataacatgga aacacgcttg gagaagaaaa gttttgaaat
    22381 gatcgcattg caacagccag ttacaactga tttgcgtatg atcattacgg tcatgaaagc
    22441 tagctcggat ttagaacgta tggccgatca tgcggtgtct gttgctaaat ccacgattcg
    22501 cgtaaaaggg cagacgagaa taccggaaat cgaaaaagag atctccgata tgtccgatta
    22561 tgtgaaaaaa atggtggaca acgtcctagt tgcttatgtc aaaacagacg aaaaagacgc
    22621 acgtacgatc gccaatatgg atcaaagagt caatgactat ttcaatcgaa tctataatgc
    22681 aacaatcaaa aatatgcagg aaaatcctga gacagtcatc agtggaacag actacttgaa
    22741 tgttgccagt tatctagaac ggatcggaga ctatgtgaca aacatctgtg aatggatcgt
    22801 ctacttggct acagggaaaa tcactgagtt aaatacgaac cacaatgaga ttttctaaac
    22861 taaagcggtg attctgccgt ttgtttagga aaagaggttg tgaaatcagc ggttgtgaaa
    22921 aagctgttct gcatcaagta ataagaacag tcaaacaaaa atagctcctc atatttttca
    22981 tttggctgga cttattaccg cagatgcaag cttttgaaca ctgtttattc gggaaagggt
    23041 ttgtgacaaa atatgtcaca aacccttttc atcatttcat agaaaggata aagaatgcaa
    23101 aaaaaaatta gcatcatcac tatatttttt atttgtgtgc ttacttcatg ggttattcag
    23161 catcaagctg ctttatatga agtacctgtc atcgagatcg aaaaagtacg aataaaagag
    23221 gatcatcaat tgattacagg aagactgatg aacacgaatc aaaaaggaga atcgatttat
    23281 ttatcggttc cttatcaaaa aaatcaaata gaaacagcaa atataaaagc gagacaaatg
    23341 tatctagtcc aaatgcatgg agatgaatgg cagctagtag caaaaaaaaa tgatggctgg
    23401 cttttcttct tcacaagtat cttcattggc gccatgttgc ttattggcgg aaaacatggt
    23461 ctatttgctt taggaagtct catcatcaat atcgttttac ttttactttt gttgctcatc
    23521 tttactaaaa tagaagggat ttctctatta aatatatcta tcctgttcgt cgttataggg
    23581 atgattatta gcatattggc tttagatgga tggaatagaa gcagtataat caaaatttca
    23641 gctgcagtta cgagtgtttt tttagcattt tttatttgtc ttttgacaat gaatctttgg
    23701 aaagaccaag gactgcgcta tgaggaactg aattatctga cacgaccgta tcgttctgtt
    23761 tttctttcta gcgtactgat tggaacagct ggaggaacac tcgataccgt tatcacagtc
    23821 attgcgacat tagaagaatt gactaagcga caaccagaaa taacagcgaa acagttatgg
    23881 ctttcgggaa ggcaagtggg tcgagatgtg attggctcga tgaccaatat ccttttgttc
    23941 gtctatatca gtgggtcagt tccatcgctt cttttatatt taggaaatca atggtcgttc
    24001 aaagaaacga tagaacagca tttatcattg gaatttttac gcgtcattgc tggcagctta
    24061 ggaatagtat tatcgatccc tatctcggtc ctcttttttc tgactgtaag gaggctgaaa
    24121 cgatgaatgt acttattata cttgttggga ttttagcaat cagcgtgcta cttattggcg
    24181 gtacgcaagg tatgtatatt cttttaggct tattcatcaa tttagggatc tttttcttgt
    24241 tgttattcgg ttatcatcag aagtggccga tactggcatt gtcggtcata ggatttttat
    24301 tgattgctgt ggttatctta ttttttatca acggttataa tctaaaaatg cgtgcagctt
    24361 ttgtgagtat actgatcttt ttattttgtt tcctactatt gcttcctatc actgattttt
    24421 tagcaatcca aggttttaca acgatagaac tagaagaatt atctggctta gataagactt
    24481 tagcgattga ttttagatta cttacgagat cgttgcttct gattagtctt agtggtgctg
    24541 ttttagatgc gagtgtagca atttctagtg ggacattcga agtatatcag gcaaatccgc
    24601 aattatcttt ttaccaattg cgccattcta gtttcgctat tgctaaaaaa atattggcgt
    24661 caacagtaat gacacttctt tttgcattca tgggaagttc tttagcgttg atcctctggt
    24721 ttattgattt agacattcct tttcagcaag tgatcaatga aaaatcattt gttctagaat
    24781 atacgatggc tattcttacc acattgtccg cactacttgt tcttccttta acctgcgtga
    24841 ctacagcata tctctttaca aaaaagaaag aacaactcaa gatggagtaa aagttacaac
    24901 ttaagtccta tgacattttt actgaatcag tgcataatat ggatgtaagg aaaagcttgc
    24961 aaacaatttt gcttaaggag gcaatttcca tgaaagaaag agaacgtatt ttagatttag
    25021 tgaaaaaagg aatcctttcg actgaagaag gcttagattt attagaaagc atggcaactg
    25081 aaaaagacga aaagcaaatc aaaaaagaag cagacaaggt aactgctagt cataaagaaa
    25141 aagatcaggc aagtcaattg atcgataaac ttgaaaacgg cgaagaagaa atttctgagc
    25201 cagttgatcc aaaggaaaga gaaagacaag atcaagaaaa cttagaaaag atcttagatg
    25261 aactagcaac tgaagcgaat aaaacttcgg cgcgtctaga tgaagtaaat gctcaattcg
    25321 ctgacaataa ggcagcacgc aatgagaaac aggaagcatt gatgcagctg aatacaaaag
    25381 aagaattagg cgagttgaca gaagaagaat tagcacagcg tcagacgtta gaagcagaaa
    25441 tcaaagagtt agaagctagt ggcgatacac tgttagaaga acaattgaaa ttagaagcag
    25501 aattaaaaga tatccgtaag aatcaatggt ctgagaaaaa agaaacgttt actgataagt
    25561 ttgaattgcc agatgattgg aaagatcaag caacagatac actgaatcaa gtaggcgaaa
    25621 aaatgtcaga agctggatca cagttaggaa aattcttgaa gaaaacattc caaactgttt
    25681 cagaaacagt gaatgacaac atggaatgga aagatgtcag cttgcgtgtc cctgggattg
    25741 cgacaacgaa atttgagcat gaattttact atgaagctcc tgcagcaagt atccttgata
    25801 tcaaggcagc aaacggaaac gtgacgttaa aaacgtggga cagcaacgat gtgaaagttg
    25861 aagctaagat caaactttac ggaaaaatgg gtgctgaacc atttgaagca ttctctgaac
    25921 ggagccagat tgaggttaat gaagatcata tctccttcca aattccaaat aaacgtgtgc
    25981 gtgcagacct tgttttctac ttacctaaac gagtatacga ccacgcagct attaaacttc
    26041 taaatggcaa catcatgatt gaaacattgg aagctaaaga tatttataca aaatctacga
    26101 atggtaacat catcgtggac caattaactg caacgatgct ggaagtagaa ggtgtaaacg
    26161 gcaatatcga tattcgaaac gggaacatct tagattctat tatcgaaaca gtaaatggta
    26221 cagtgacatt tggtgcgaca gcagaaaacc tttctgtgtc tttggtaaat ggtgatgtac
    26281 gtcttacgat taaagaagat aatttgaaaa aagtagaagc aagttcagtg aacggaaatg
    26341 tcaaagtcgc tttaccagat ggcatcggtt tggaaggaca tgctaaaaca agtcttggaa
    26401 gtatcaacag ccgtctgtcc aattacgaag tagttcgtga gaaaaaagaa cggacaaacc
    26461 aaatgttgca attccgtcgt gtttcagatg gtgaaatcgc gcaagtgcaa ctttcaacga
    26521 caacaggaag tatctattta aaagatacag ataaataaag aggttgtgaa agagatgttc
    26581 agccttgagc aataagaagc gattttgtaa aatagcttcc cctattttac aaaattgtgc
    26641 cttattgccg ataggctatc tcttgaacac cgtttaccaa gagattatga acttgccaat
    26701 tatcgccgag tcacaaggaa taatttcaaa aaaagctcgt cacgttttat gaatatggta
    26761 atttgtgacc gagaattttg caaaaagaca ccgattaaga agaaggttgt cacaacgatt
    26821 ttcttcattt aaaatagtag aacagaggtg agacatgatg aaaaaaaagt tgacaaaatc
    26881 caataaaaat gttgttttga cagggacttt agcaggaata ggagaataca tcgggattga
    26941 tccgactgtt atccgtgtgc tttatgtatt cctgagctta gttgcttttg gaagtccaat
    27001 cattttatac attttattag ctttgattat cccatctgcg cgttctgcac gaacaaacta
    27061 tggacataac aatgcatatt atgaaaaaaa caattatcgt gaacaaactc gtgaacaaac
    27121 aaaaaaacgc aaagaagcgg aaaaaatcga tgatgacgaa tggagtgact tttaatgtcg
    27181 tactttcaac gtattttagt taatacgtta acattcatat cattggctgt tctttttcct
    27241 gcgatggtcc atgtgagcag tatttggacg gccgttcttg ccagcttcgt attgtctgtg
    27301 ttgaatatgt ttgtcaaacc gattttgacg atactgtccc tgccctttac attagtcaca
    27361 ttgggattgt ttacgtttgt tatcaatgca gcgattctta aaatgacctc cttttttgtg
    27421 ggagcagaac attttagttt ttcttcattc ggtgcagcgt tgttagtagc tatcttgatg
    27481 tcgcttgtca atgtaattgt cagcgaacat aacagtagaa aataaaagaa agctgtgccg
    27541 aactatcggc gcagtttttt tatttagaat caggaatgcg ttttctatta cattggtaat
    27601 taaataaaaa cgtttttttt aattggtagt acttttggct agacaatgat aaaatgatag
    27661 agaacactct aatagaaatg aggtagcatg aatgtcagaa gttgtaaaag ttagccaatt
    27721 agtgaaaaaa ttatctttgg aaatcgtgac aggcgacgag aaaagcttag accgtgtcat
    27781 cgtaactggg gacatctcac gcccaggact agagttgact ggttatttta attattattc
    27841 ccataatcgt ttacagctat ttggcagtaa agaaatcagt tttgcggaac ggatgatccc
    27901 agaagagcgt ttgatcatca tgagaagatt atgtagtgaa gatatgcccg catttattat
    27961 ttcaagagga ttaccagctc cagaagaaat gatccaggca gcaaatgaaa atgggatagc
    28021 tgtactgcgt tctcccatct caacttctcg cttattagga gaattatcca gttatttaga
    28081 tggtcgcctt gcccctcgaa caagtgtcca cggtgtttta gtggatgttt acggattagg
    28141 tgtactgatt caaggtgaca gtgggatagg aaaaagtgaa acagcgttgg agttgatcaa
    28201 acgcggtcat cgattgatcg cagacgatcg agtagatgtt tatcagcaag atgaattaac
    28261 ggtgatcgga gaaccgccta aaatcctgga acatctgatt gaaatccgag gaatcgggat
    28321 cattgatgta atgaatcttt ttggtgcgag tgcggtacgt ggctctatgc aagtccagtt
    28381 ggctgtttat ctggaagcat gggcaaaaga taagaaatac gaccgtctgg gctctgaaga
    28441 cacgaccgtt gaaatcgcgg aagtaggcat tccacaaata aaaatccctg tcaaaacagg
    28501 acgaaacgtt gcaatcatca ttgaagtagc cgcgatgaat ttccgtgcac gtacaatggg
    28561 ctttgacgca acgaaaacat ttgaagaaag attaagtcgc ttgattgaag aaaactcagg
    28621 caacgactag caaggagtga caatatgtta gcacaaatca atcgagttgc ttttgagctt
    28681 gtagggattc ctatctactg gtatgcattg atcatcgtat caggtatcat tatcgccatg
    28741 tggcttagca gcagagaggc tgttcgggta ggattaaaag cagatgatgt gacagatttt
    28801 atgttgtggg gattgcctat ctccattatt ggcgctcgct tatattatgt tttatttgat
    28861 cttccccagt atatagctga tccaatccaa atattcaata tccgttcagg aggcttagct
    28921 atttatggcg gactgattgc aggcgcgatc acgctgtatt tttttactaa atatcatttt
    28981 atttctttgt ggactttttt agatatcgct gcaccaagtg tattattagc acaagcaatc
    29041 ggtcgttggg gaaatttcat gaaccacgaa gcatatggac cagacacgac gcgaagcttc
    29101 ttagaaagtc tgcatttacc gcaattcatc attgataata tgtatatcga agggatctat
    29161 cgtcaaccaa catttcttta tgaatcactt tggagtttga ttggatttat tttgcttttg
    29221 tttttacgaa agaaaccaca ccttttgaaa aaaggtgaag tccttttatg ttatctaatg
    29281 tggtatagtt tcgggcgttt ctttattgaa ggattacgta cagacagtct ttacttttta
    29341 ggtgtgatcc gtatttctca attattatct gctgtgttat ttgtcggtac attgattcta
    29401 tttatttggc gcagaaaaaa aggaaattta ccggattatg accgctcatt aggaaaaaat
    29461 caacaaatta tctgattttt agagcgttaa aaatgaaaaa aatttcagga gtggtaaaat
    29521 gaattataga gtagcggttt taggaccagg ctcttggggt actgctttgg cacaagtcct
    29581 cgccgaaaac ggacatgacg ttcggatttg gggacatcgt gcttcacaag tagaagaaat
    29641 caacacccaa cacacgaatc aacgttattt accagatcat tgtctacccg attccatcca
    29701 agcattcacc aatatggaag atgcagtaaa agacgcagat gcggtgctat tcgtcattcc
    29761 aacgaaagca atacgttctg ttgcaaaaga actagtgcct aaattgaata caaagccagt
    29821 gatcatccat gcaagtaaag gattagaaca ggggacacat aaaaggatct ctgacatctt
    29881 gttagaggaa atcccagtag aaaaaagaaa agctgttgtt gttctttctg gaccaagcca
    29941 tgcagaagaa gtagcgaaac atgacatcac tacgatcaca gctgcaagta cagatgcaaa
    30001 agcagcaaaa tatgtacaag agctgttcat gaataattat tttcggatct ataccaatcc
    30061 tgatgtgatc ggtgtagaga tgggggcagc tttgaaaaat attattgcta ttggtgctgg
    30121 cgctattcac ggcttagggt ttggcgataa tgcaaaggca gcaatcatga cgcgcggatt
    30181 agctgagatc agccgtttag gtgtagcaat gggtgccaac ccgctgacct ttatcggatt
    30241 aagcggagta ggcgatctag tcgttacttg cacaagtgtt cattctagga actggcgcgc
    30301 aggcaacttg ttaggacaag ggcagcccct agaagaggtg ctagccaata tgggaatggt
    30361 cgttgaaggt gtgaatacta cccaagcagc gatggaacta gcccaaataa tggaaatcga
    30421 aatgcccatc actcaaacaa tctatgaagt gctgtatgaa caaaaagaaa tcaaaacagc
    30481 cgcaaaagaa atcatgttac gtgatgggaa aaaagaaaat gaattctcat taacaatttt
    30541 ttgaaggagc gaatgtatat gaaagtcaaa aaagcagtta ttccagcagc aggattagga
    30601 acaagatttt taccagcaac aaaagctatg gcaaaggaaa tgttgccaat tgttgataaa
    30661 ccaacaatcc agttcatcgt tgaagaagcg ttgaaatcag gtatcgaaga catcttgatc
    30721 gttacaggaa aagctaaacg accaatcgaa gatcactttg attcaaatat tgaattagaa
    30781 acaaacctaa gtgaaaaagg aaagaccgaa ttattgaaat tagtagaaga aacgacagat
    30841 gtcaacttgc atttcatccg tcaatctcat ccaaagggtt taggacatgc cgttcttcaa
    30901 gcaagagcct ttattggaaa tgaaccattt gtcgttatgc taggcgatga tataatggaa
    30961 gacgaagtac cattgacaca gcaattaatc gatgattacg aacgtactca tgcttctacg
    31021 atcgccgtta tgcaagttcc tcatgatgaa acttcaaaat acggaattat caatccagga
    31081 gaagtattgg aagatgggtt atacaatgtc aaaaactttg ttgaaaaacc agatccaagc
    31141 aaagcaccaa gtgatttagc tattattgga cgttacttat tgactccaga aatttttgat
    31201 gtattgtccg agcaacaacc aggagccgga aatgaaatcc aactaactga cgcaatcgat
    31261 acattgaata aaacacaacg cgtatttgcc cgtaaattca caggtaaacg ttacgatgtc
    31321 ggtgacaaat ttggttttat gaaaacaagt attgaatatg gtctaacaca tccagaagta
    31381 ggtgcacctt tacgtgagta catcctgtct ttaggtaaaa cattagaagc agaaggaagc
    31441 aagatcgatc ataatccaaa aggaataaca gaaatcaaag aagaaaagaa aaaataaccc
    31501 ttttttctaa cgagcttcag ctgctaattg aataaaaagt agttgaagct cgtttttatt
    31561 tgtttaaaaa acacgaaaat gctatcctta tagaaaagag agacaagaag ggagtttgat
    31621 catgtcagga ggagaaattg caggattgat cgcagcaatc gcctttgcga tacttgtcgt
    31681 ttttatcgtt cgtgtgttgt tgcaagtttc taaaacttta gaaaaagtag atcagactgt
    31741 agcagaagca aatacgacga tcgaaatcgt cacaaaagac gtagatcttt tgtctagaca
    31801 agtagaaggc ttactggtca aaagtaatga actgctcttg gatatcaatg gaaaagtcgc
    31861 aacgatcgat ccattgttca cagcagttgc tgatttaagt gaaagtgtat cagaacttaa
    31921 tcattctagt aaaaacatcg cgacgaaagt cggcggaatc ggtaaaacga cagctaaagc
    31981 gacggttgcc ggaaaagtcg gtgggacagc gatgaaattt tttaaaaaca aaaaacatac
    32041 tgaaacgaca ggaggaaaat aaaaatggct aaaaaaggtg gatttttatt aggtgcagta
    32101 gtcggaggca cagccgcagc aatcgccgcg ttattgttag caccaaaatc tggtaaagaa
    32161 cttcgggatg aattagctgc ccaagcggat gatttgatgg atatggcttc agattacaca
    32221 gatatggcga aagaaaaatc gactgagtta acaggtattg caaaagaaaa agcgcaagat
    32281 ctttctcaac aagcaggtga tctagcaggt agtgtcaaac aaaaagtaag tgaatcagca
    32341 gatgaagcag gaagtgaatc tgacgatatc ttgttaaatc ttaaagaaca atcagctgac
    32401 ttatctaatc gtttcaaaaa aacggcagaa gatatgaaaa aacctgcaga tgaattagga
    32461 agtattgcta aagatacttc agaagatatc ataattgatg taaaagacgc tgctggtaaa
    32521 gcaggagata ctgtcaatga aggaatgtca gaagcaaaac cagttgcaga tgactcaaaa
    32581 gaaatgatga aaatggcaaa agaagatgcg aaagaagcta aaaaagaaat aaaagataca
    32641 atgacagatt catctacaaa tcactaaaat cacaaattta tagaataaaa
//
LOCUS       DAPBCF010000026        31574 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.026, whole genome shotgun sequence.
ACCESSION   DAPBCF010000026 DAPBCF010000000
VERSION     DAPBCF010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 31574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.026"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(193..378)
                     /locus_tag="RD508_001553"
     CDS             complement(193..378)
                     /locus_tag="RD508_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736160.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(1228..1569)
                     /locus_tag="RD508_001554"
     CDS             complement(1228..1569)
                     /locus_tag="RD508_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDT7736161.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(1569..1799)
                     /locus_tag="RD508_001555"
     CDS             complement(1569..1799)
                     /locus_tag="RD508_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7736162.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            2095..2433
                     /locus_tag="RD508_001556"
     CDS             2095..2433
                     /locus_tag="RD508_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736163.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPIQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(2638..3213)
                     /locus_tag="RD508_001557"
     CDS             complement(2638..3213)
                     /locus_tag="RD508_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HDT7736164.1"
                     /translation="MCGRYFFDLESELLQNYYREAQKKQPEQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLIINARAETVEEKKTFHQPFLQNRCVFPMSGF
                     YEWNEEKDKFMFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRMPLVL
                     TEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(3576..4157)
                     /locus_tag="RD508_001558"
     CDS             complement(3576..4157)
                     /locus_tag="RD508_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7736165.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASETGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(4350..4976)
                     /locus_tag="RD508_001559"
     CDS             complement(4350..4976)
                     /locus_tag="RD508_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7736166.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYEPVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(4998..6329)
                     /locus_tag="RD508_001560"
     CDS             complement(4998..6329)
                     /locus_tag="RD508_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HDT7736167.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHPEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENTRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(6484..6885)
                     /locus_tag="RD508_001561"
     CDS             complement(6484..6885)
                     /locus_tag="RD508_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HDT7736168.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(6971..7177)
                     /locus_tag="RD508_001562"
     CDS             complement(6971..7177)
                     /locus_tag="RD508_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736169.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(7272..8774)
                     /locus_tag="RD508_001563"
                     /pseudo
     CDS             complement(7272..8774)
                     /locus_tag="RD508_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
     gene            complement(8792..9247)
                     /gene="argR"
                     /locus_tag="RD508_001564"
     CDS             complement(8792..9247)
                     /gene="argR"
                     /locus_tag="RD508_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HDT7736170.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(9345..9752)
                     /locus_tag="RD508_001565"
                     /pseudo
     CDS             complement(9345..9752)
                     /locus_tag="RD508_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323732.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
     gene            complement(9767..9961)
                     /locus_tag="RD508_001566"
     CDS             complement(9767..9961)
                     /locus_tag="RD508_001566"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736171.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKPFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKIG"
     gene            10182..11555
                     /locus_tag="RD508_001567"
     CDS             10182..11555
                     /locus_tag="RD508_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7736172.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEKLQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            11630..12742
                     /locus_tag="RD508_001568"
     CDS             11630..12742
                     /locus_tag="RD508_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDT7736173.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTSHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(12814..14451)
                     /locus_tag="RD508_001569"
     CDS             complement(12814..14451)
                     /locus_tag="RD508_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HDT7736174.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILKTYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(14619..15227)
                     /locus_tag="RD508_001570"
     CDS             complement(14619..15227)
                     /locus_tag="RD508_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7736175.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(15611..16762)
                     /gene="queG"
                     /locus_tag="RD508_001571"
     CDS             complement(15611..16762)
                     /gene="queG"
                     /locus_tag="RD508_001571"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDT7736176.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEVYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(16781..17533)
                     /locus_tag="RD508_001572"
     CDS             complement(16781..17533)
                     /locus_tag="RD508_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736177.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFIPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(17673..18623)
                     /locus_tag="RD508_001573"
     CDS             complement(17673..18623)
                     /locus_tag="RD508_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HDT7736178.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKGKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQIKES"
     gene            complement(18624..19463)
                     /locus_tag="RD508_001574"
     CDS             complement(18624..19463)
                     /locus_tag="RD508_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDT7736179.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(19460..20206)
                     /locus_tag="RD508_001575"
     CDS             complement(19460..20206)
                     /locus_tag="RD508_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDT7736180.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQPVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            20444..21814
                     /locus_tag="RD508_001576"
     CDS             20444..21814
                     /locus_tag="RD508_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7736181.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQTVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAMNGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(21869..22765)
                     /locus_tag="RD508_001577"
     CDS             complement(21869..22765)
                     /locus_tag="RD508_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7736182.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVKDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDPSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(22879..23049)
                     /locus_tag="RD508_001578"
     CDS             complement(22879..23049)
                     /locus_tag="RD508_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736183.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(23046..23723)
                     /locus_tag="RD508_001579"
     CDS             complement(23046..23723)
                     /locus_tag="RD508_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDT7736184.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGNSL"
     gene            complement(23814..24719)
                     /locus_tag="RD508_001580"
     CDS             complement(23814..24719)
                     /locus_tag="RD508_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDT7736185.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            24894..26348
                     /locus_tag="RD508_001581"
     CDS             24894..26348
                     /locus_tag="RD508_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7736186.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVT
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEELENKLAPADTMEDELHDAVVPSH"
     gene            26364..27395
                     /locus_tag="RD508_001582"
     CDS             26364..27395
                     /locus_tag="RD508_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDT7736187.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTQDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENTTGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLDKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            27402..28589
                     /locus_tag="RD508_001583"
     CDS             27402..28589
                     /locus_tag="RD508_001583"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HDT7736188.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            28745..30127
                     /locus_tag="RD508_001584"
     CDS             28745..30127
                     /locus_tag="RD508_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HDT7736189.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            30099..30485
                     /locus_tag="RD508_001585"
     CDS             30099..30485
                     /locus_tag="RD508_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736190.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(30681..31349)
                     /locus_tag="RD508_001586"
     CDS             complement(30681..31349)
                     /locus_tag="RD508_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDT7736191.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFSLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTESWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT         8946 a         6384 c         5693 g        10551 t
ORIGIN      
        1 ataacagctg aaaagatagg acttactctt agtaaagtat ctgaactatt aatttttaaa
       61 ctatcatttt tatcctcaac tacatacata tctgttgcaa cttcactttc tgtctcatcc
      121 agataaatga ttaaggaatc gggaattgca atatcttcag ctgacgctgg aatagttgag
      181 ccaaattagt catcatatct ttattataaa ataaccaaca gcaaaaaata caatgaaaaa
      241 caaacttgga actaatgtat cattaataaa tgttgaaaaa ttcagcaact cattactgta
      301 tgattttagc agcccaacca acatataccc tataaaagct aataagatgg ttaggaatcc
      361 tttagaattt ttactcattc ataaacactt ccttaaatag cttttattat agaaggtatt
      421 gtaaataata atattgacaa aaagtgactc aaaataaaaa aaaccttaca ttatactgga
      481 atgaactgta ttgatagtgt acctaaaagc tctactgaca taagatcgtg taatcggtaa
      541 agtaatttta ttaattatac gggatgtaat caattagaga ataaactaat cataaaaggt
      601 acttttacat tcataattgt cgctttgaga ttctactttg gttcactatc tgacccaatt
      661 gcacattttc gagcattaca agtattggtg tcgttagaac aactaaatag aaactagcgg
      721 tagatttttc agaatctatg ctaatttctg tacggatgtt ccagtgatgg caaatttctc
      781 ttttcattgt ttttcttgtc gcatgatatg cctttttgtg ttattcagtt aaactataga
      841 aattctttcc tagacagatc ttgatcccaa attttacgtt tttgagcatc gatatagttt
      901 aaaatgacat tactcatatc taaagagttt agatttttta ggactaaaac tgtcagttgt
      961 tctttttctt ctttctgtta aagtattgtc gcgacttttc gtatacgtta agatatgtcg
     1021 tgaaaaaaca agttttgtga cacaaaaaaa cgaatgactt gaggaaatca cctcaatcat
     1081 tcgtttaaaa tgctatatat tctttagttt aagatacgga aattaatccc atcgaccaca
     1141 ctagtagaat gaacgacatt tacttggcct ttttttaatt tcgttatgtt tagcatataa
     1201 aaatattata gagtttactt acaatgctta aaacatatac tgtataatct gatcaatttt
     1261 agccatgtct tgcaatggta agttttctat ttttttgagt tttcgttcct taaaatcaag
     1321 agattttaat tgtgtaataa ttacttgtcc ttttatatct agctcttcag gtaatgagta
     1381 acgtgtcggt aaattcttta tagtggaagt aattggacat atgaccgaaa acattgtttt
     1441 acggttaaat tcataacgag agacgactag tcctggtcgt cttttttgaa tttcttttcc
     1501 tactgaggga tcaaaatcaa tccatacaat atcacctttt ttaggaatat aaattctttc
     1561 ttctgacact ataaaatttc tctcccttca ggagttaaat cttcccattc gtctttctca
     1621 taatactcgg cctcttcccc accactaaat ggatcttcaa tttttggaac taacgtaatt
     1681 gttccatcat cagaatacac aacgatatat tcttggtttt ctgaaggttt ctttccgtta
     1741 tcagaaggta aagttaccac tacagaactt ccttgtaatc tagattttgt aacaagcatt
     1801 atcatcactc ccttaataaa agtatactat ataacactaa gtaacgcaaa attccccttt
     1861 gtaaactatc tagaaaattg ttttgtttaa agtatatctt attggatata aatagaaata
     1921 aattgtagcc agttcatttt ttctttaaat aaaaaaataa tccaagaaac attgaaccta
     1981 tggatccaaa agctacccaa atactatagc taactccccg ctaccttcaa tcttgcagat
     2041 aaaacgcttt ggaaaaaaat cgagaaaatc gcaaagacga caggccatcc tatcatgcct
     2101 gattataaac aaaaagctgg ctattccttt tgctctgaca aatttcaatt gggaaagttc
     2161 acgaaactag caggtgaaga agtttcaact gttcggatta aagaatgccc gattcaaata
     2221 gaaacattgg ttcaacgaat ttcaactaga caagactttg ctattgtaga acgtgagatc
     2281 gtagctattt ttgtagaaga agggatttta catgatccaa ctcatatcaa tgtggataaa
     2341 tggcaacctc ttatctataa attcagagaa tatacaactg ccaaccagtc gttaactttg
     2401 aattttagat tccaagaatt caaagagtca taatgataaa catcgttagg tataaataaa
     2461 aaagactcgc agcacgagta aaaaacaaat agaagctata cattagaaag gtcgactgtg
     2521 accctataga tgcagtatat gcagcttatg agcatttctt ctgttctctt tgtttttggg
     2581 atctgtgctg aagtcttttt cgttttttgc cgctctttct ttgaaaaatc gattatgtta
     2641 taccttctcc attactaatt caggcatctg ctgagtaatg atttttcgcg caaaagaaat
     2701 atctgttacc caaggttcga tttgttcttc agtcaagaca agcggcattc ggtcatggat
     2761 tggtgcgact gtgcggttag gttcagtagt cattatgatt gattctgcca ttttttcatc
     2821 ctgatggcta cgataaaaac cgccaatata cactattttt tccttatttg aaaacataaa
     2881 tttgtctttt tcttcattcc actcataaaa gccactcatt gggaaaacac aacgattttg
     2941 caaaaatggt tgatgaaagg tctttttttc ttctactgtc tctgcacggg cattgattat
     3001 caattgtcct tttttaaatc cggtaaatcc ccacttcatg atttccggag tgaggatgtt
     3061 ttcttcctct tttcttaacg taacaacaag atttgaagga aaaacttctc cagctgctaa
     3121 ttctgctgcc tgctccggtt gtttcttctg ggcttctcga taataattct gaaggagctc
     3181 tgactctaga tcaaaaaaat aacgaccaca catcctaatc cctcccaatt ttttttctat
     3241 catacactgc aacaagaagt tcgcaccaac aaaacgcttt caatttgtgt agaactaaaa
     3301 aagttgtgac aagtgacaaa ctctccagtg aatggtattc tcctgccaac tcctcggtca
     3361 caagtcacaa tattcaacaa acatgagaag ctgttttttg aaattgttcc ttgtgacccg
     3421 aagtgaaacg gcaggcttac gacctctggg taaacggtgt tcaaaagctt gcatctgcgg
     3481 taataagccc aaccaaacga aaaacatgag cagctatttt tatttggctg ttcttattac
     3541 ttgatgcagg gcagcttttt cacaacctct aattattaaa gaaccttttg cgaagttaac
     3601 aatctttctt tgatcaattg aaaattttgt ctaagtagtg atagatcctg tgtgactttc
     3661 aacaataaga tacttccctg gatttcagca atcaacgctt tggcttgacg gtctgcttct
     3721 tcatcggaca gtttttcttc agaaagtgcc aggatatttt gtttcgtata cttgacccat
     3781 tgattgacta attctagtag caacagacgg tattcttcat ccactgtact caactcaata
     3841 atcaaattac ctacaggaca gccatgataa gtgatctgtg tctcatgatc agcaaaaatc
     3901 cagtccaaca tttcttctaa tgcttcttct ggctgttttc cagcatttaa gatgtcttcg
     3961 aacaattctg tctgccacac gtccatatgc gcatggatca ccgctagaca aacttctttt
     4021 tttgaagaaa agtaataata aaattgccct ttccccgtct cagaagctgc tagaatatct
     4081 cggattgacg tttcatgata gcctttttta taaataagat ctttggtcgc ttccaagatc
     4141 ttttcctttg ttttcaatga tattctcctt tttcatttct catagtccta tattatacaa
     4201 taaattcatc attttttctt cttaatcgtt taaaaaagac tgtgccaaat tatctgacac
     4261 agccctcact ataaaactgt tctcatgtgt tctcatatag ctagatgttc attgattcaa
     4321 gaactgcgag gacaaaagca gttcctatct tatgatagtt gctctaatac ttcctctgtt
     4381 gtcatcactt gatctgcaat aaagccaaag ttcgtcaacg ctgcatccat tgcttcttgg
     4441 ccaggagcac caattgcatc tgtcgctaca acaacattga atccactctc taccaattca
     4501 cgcatatggg aatcgctaca caagtttccg ttcattccac cgagaattac tgtgtcgatt
     4561 ccattttttc tcaattgaag cgccaaatca ttgctttctg gtccaaagat tttatgagga
     4621 gagctgatga tcgtattttc atccaaatat ggtttcaatt cttcgataaa atcggctcct
     4681 gaaccttctt cgactggttc atattgactt tttctagcaa acatctgctg ctcaagcatc
     4741 atatgttctc ctgcaccgcc aaattgccat ttatggtcat gtggataaaa ataatgagga
     4801 gaaataaaga gtttgtatcc tttttctttt gcttgtttca ccatttcgat catattttcg
     4861 atcgtattgt atttttctaa gatatctttt gtcaaaccaa agccaccgcc tgctggtttc
     4921 aagaactcga cttgcgggtc agttagaact actgctgtat ttttgttgtt gaacatgata
     4981 aattctccat tcgttattta ttttaataca tcatttagag cttcactcat tgttggatga
     5041 gaatagattt gatctctcaa taacgtataa ggaagttttc cattcatagc tagcgaaatc
     5101 aagttgatga cttcatgaga atcttccgca tagatacttg cccctagaat caagtcagtt
     5161 tcagggtcga ctaaaacttt gaatactcct ttaggatctt ctaatacttg tgctttagga
     5221 acaccgcttg tcatatactt gaataatttg taattgacgc cttgtgcttt ggcttgtttt
     5281 tctgttaatc ctacattgga taaagttgga gtgataaata cactgtaagg cacagctttc
     5341 cggttattcg ttgttcgtgt attctcgcct ttcaactgat ccatgataat tcgataatca
     5401 tctagagaaa tataagtgaa ctgcaatccg cctttgacgt ctccaatcgc ccaaatgttg
     5461 tctgcatctg tacgaaggta ttcatccaca gcgattgctc cgcgatctgt tagtttaaca
     5521 tctgtatttt ctaatccaag tgatgctgta cttggttttc ttccagttgc agccaaaact
     5581 tttgacgctt ggattgttac ttcttggcca tcttctgtaa aggtgacggc agctgttgat
     5641 tcttggtctg ctacttgatc tacagataca cctagatgga attcgattcc cgcatttgtc
     5701 atgtcttcta aaatcatttg cgcgatatct tcatcttcac gaggaagaaa ttcaggatgg
     5761 gcatcaagaa cgacaacttt agatccgtat tcattgaaca ttgatgcaaa ttccaagcca
     5821 atatatccag ccccgatgat cactaatttt tccggtaatt gttcctgatc catcgcttgc
     5881 gtagaatcaa tcaagtagcg acttgtattc aatcctttga ttggtaaaat gattggttca
     5941 gaaccagtat tgatgaaaat ccgttcgcct tcaacaatca ctttttcacc attattcgtc
     6001 acttcgattt gatggttaga aagaaaacgt gctgtaccgt ccatcactgt cccagttgcc
     6061 tcatcgctga tcatatgata atttttggct cgaagcatgc ccgtcaattt ttctttccga
     6121 gcaacagcct ctgtaaagtc gattcctctt tctccattga aaatcaatga tttagaagga
     6181 atacagccga tgttgataca tgttccgcca tacatacgtg ttgacttttc aacgactaaa
     6241 accgattcgc cttttgaagc taacgccttt gctaaagtct taccgccctt tccaaaaccg
     6301 atcacaatat tttgatattt ttccatcatt tttccctcgc ttctttttta cctaccgatt
     6361 ggtacaaaaa tatgataacc gataatcgtc tattttccca atcatctgct ttatttgtca
     6421 aaaaaaacca gacaaaaagc ggtcctttca cgtttttagt ctggttcgat ttcctttatt
     6481 cttctaaaca atcgttactt ctacatcgat atttcctcta gttgctttgg agtaagggca
     6541 gaattcatgc gcatcttctg caattttttg ggcttcttct tcgctgatgc catcgatatg
     6601 cacttctaac actacaccga tctgatagcc gccatcatct aaattataaa gagagacacg
     6661 tgcttttact gtggactctg ctgtcattcc tgcttctttg atcatatgtt gtaccgcccc
     6721 attgaaacaa gaagcataac ctgctgcaaa taattgttct ggatttgttc cttctgcatg
     6781 gattcctgga ggagtgattt tcatatgcat cgagccattt ggtgcctcga cttctccatt
     6841 gcgcccgcca tggttgatca ttgctgtttc gtatgctttt ttcattgtac tgctcctttc
     6901 gattgaccat ttgctacttg gctataatta tagtgtatga caagtaaggc gctttctaca
     6961 aaaattctgc ttattcgaat accagaatgc cgtcttctac tatttttcca aaaaacaaaa
     7021 aaatactact cgtgaacaac agcgtcatat ttgttccaaa ataaattgca atcttttcta
     7081 cataatcttt tatatgattg attttaagat acatatatac cagaaagttg accccataaa
     7141 ccaatactgt taaaaaaata accatattcg ttaccatttt ttcctccttt tgctggtctc
     7201 cctaccagca ttcgatttaa ccataccact ttttttgccg tccaagcaac tagcctttca
     7261 aaaagactgg tttattctgc tgttaatgat tcaagatcag aaaaatgtcc gaataatttt
     7321 gctaatttta ctaacgccaa cttgttcttt ccgaattcat cattttctat ctgtaatact
     7381 agtaacggct catgtaagct taaacggatc aaaaaccagc cgtttccgta tggctcttct
     7441 agatcatacc gaataccttc ttcatttttc gggtcgaagt tcatcccttt ttcttcttcc
     7501 aacagtcgct tcatttcttc taatatcttg tttccttgtt cgcgtggttc atcgctgaac
     7561 aattttagtc ggatttcttg tacttctacg ggctgtttca actctttgat ttgttcatct
     7621 aatgtgatac cttttctttt taattctggc aaaagcatca ggatctttgc gatgacatat
     7681 gcaccatcat ccagaaaata attttccttg aatgcagcgt gtccgcttgt ttcgatggct
     7741 agctgtgtat ctttcccaag acggttaagt tctaatgctt tattgattac atttcgatag
     7801 ccggaaatat aacgaacttg gatgcctcct ttttcttcaa tgaatctttg tagatgagaa
     7861 gaagtagggg aattcgtcac gattcttgtt cctggatgct cttttaatac gattgtactt
     7921 aatactgcga tcaaattatt tcgattgatc actgttccag aagcactgac aactgcagaa
     7981 cgatccacat ctgtatcgaa aatgatccca agatctgctt catttgctaa aacagcctgc
     8041 ttgatacttt ccatcgcttc tttattatca ggatttggga tatgattagg aaatcggcca
     8101 tctggttcca aaaattggga acctgttgaa tccgcaccta agctattcaa tactttttca
     8161 gcaaagaatc caccagcacc atttccggca tcaacaatga ttttccaacc atttagtggt
     8221 ttgctttcta gtgttccaat ccccttttta atttttgtga ctaaatcttg cgcataaggt
     8281 gtcaaaaggt ctgctttttc tacgcttcca gtttgttcgc tttttatttt ttgctgctgt
     8341 gataggataa aagcaatatc ttctttttct gctcctcctt ctgaggtaaa gaattttatt
     8401 ccattataat aatagggaag atggctagca gtcagcataa ccgcagcatc gcacgagaac
     8461 tgttcaaatt gagtggacat aaacatagca ggcgtagtag ctaattcgaa atcgatgaca
     8521 tgtatccctt gttctttcag actttggatc aacgcctctt tcagtgctgg tccgcttatc
     8581 ctactgtcat gaccaatccc aatcgtccat tttttatttg gatcggttga tttcttcttt
     8641 ttctttatcc agtttgctag tccccagccg atctttttta ccatgtctgt cgtcaagttt
     8701 acttcatatc cttcaactgg taatgcgatt cctcgaatat ccgatccatt ttacagcgct
     8761 ttcatatctt tcatataaaa gtcctcctca tttattccct cattttttcc agcttttctg
     8821 caaatcgctg tgcttcttct tctgagcggc aaataataat gaatgtatct acaccggcca
     8881 tcgttccgac aacttcaggg taagccactt catctagcca attcgttacc acatcggcac
     8941 catttcgttc agtcaatacg atgaccatga actgaacaga ctggatacgc aaaacctcgc
     9001 gtctaattgc tgtacgcaaa cgttcttcat ttaaagaaac agatggctgg ttaaataatg
     9061 tatagcgtac tattttgttt tcattttgac tttttactaa cttcatttct cgaatgtctc
     9121 gagaaatcgt tgcttgagtc acatcggcgc ctgcttcatg cagccgcgca agcagctctt
     9181 cctgtgtccc aataggttgt tctgtaatga tctggcggat cagtgcttgt cgctgtttct
     9241 ttttcatatt agacacctct caatgttgat tatagcaaaa gataagtaat atttcttcat
     9301 attttggtat tttttacttt tattttttgt tttcattcag gttgctaacc tttttctatt
     9361 ttaacacgca aaatcgtctt cattttttca ggtgctgatt ttcttggatc gctgatgtaa
     9421 atctctttgt gttctttaga agctctttca tagccttctt ttgcgatgaa tgcttctaat
     9481 ttctcaaacg ttgctggttc ttcgtcatag ggcccgacgt gtaagatttg ggcacaaaga
     9541 ccttcttcca tctttttgaa tactacttgt tctttcaagt cttccggaag tttgctagaa
     9601 cgctgaatgg cttcttgtgc tatcgcttct gtaacaaagt caggctgtca gatcatcaat
     9661 tgataagaaa aatgttcttt tttcatcact ggttcatgca aatacttttc ttgcagtccc
     9721 cattgtcctt ccagtggata gacagtatac atctgataat caggaatcag ccaatttttt
     9781 taggcgacat gcgtattgca tagctgactg catatagaca ggctactctt cgtttaaagt
     9841 cttcctgatt cgggtcgccg atccctctga tgctaaagaa tggtttttta ggaacctcta
     9901 gtatttgcgg gctttttttc atactatagc tcttgtcttt acgccattca attttttcca
     9961 tttttcttcc tccgcgaaat tccatttagt tatttattat catacctctt tttgagtgac
    10021 ttggctaatc gtgttgacac tatttttcag tttgtgctag aataagtgaa gtaaataaat
    10081 cgtacagata acacgtttcg gcgtgtcgag agagaggcgg tttctatttt tataatagaa
    10141 atcactctct ttttttacga aattttttag aggtgatgta aatgacaaaa caaaaacagc
    10201 tgcttttagt acctgcagta attgcaacag ggatgatgtc ttttgcgggc gtattgatcg
    10261 agacggccat gaatgtaact ttcccaactc ttatcagaca gtttgattta acgactgcac
    10321 aagtccaatg ggtaacaacg atttatcttt tgatgatttc gatcattgtt ccgctgtcta
    10381 cttatttgaa tcgcaatttt agtctcaaaa aactcttttt agcttcaaat ctgcttttct
    10441 tggcaggtat aatgatcgat ttcttctctc ctaccttcat ggtcctattg tttggtcgat
    10501 tgctccaagg tgcagcgaca ggtatcgctc ttccgttgat gttccatatt atcttgacat
    10561 ttgcccccct caatcgacga ggcgcgatga tgggtgtcgg tactttgaca acggccattg
    10621 ctccagcaat tggtcccact tatggaggca ttatgacttc acattttaca tggaatcata
    10681 tcttcctgtt tcttgtgccc gttttgattc tttctttgat tatcggctgg tttgctattc
    10741 ccgagatggc agtacaaaaa agtggttatt tggattggat aagcgtttta ggaatttgtc
    10801 ttttgtttag tggaagtcta acatttttga gtacgttggg aacagtttcc agctggattg
    10861 ctttaatcat cggcggtatt ggctggttcc ttttttacta tcgaagtaaa aaagtggagc
    10921 atccgctgat ccgactgtct attctttcaa ataaaacatt ccgcttgttt ttgattggct
    10981 tcttagttta tcagttttta ttacttggtg tatcttttgt cttgccgaat ttccttcaga
    11041 tcgttcaagg aagtagtcct tttgtcgctg gattagcgat gcttcccggc gcagcggttg
    11101 gtgctttgct ttctcctttt tccgggaaaa tgctggatca atatggtccg aagaagccaa
    11161 tttttgctgg gctgattctt tctttgattg gttggctagc attattccta ctcataggac
    11221 acgcttcagt gggtgtattg attgcttgtc atgtgtttta tatgatcggt atcggattat
    11281 cttacagcaa tatgatgacc accggaatga atgcactgaa tgaaaaacta caaggagacg
    11341 ggaacgcaat gttcaatacc ttgcagcagt tttctggcgc tgtggctact tcattagtag
    11401 cggtcattat caattacgtc cagcatcata cttcccataa ctatgaagtg tctactacat
    11461 taggatcaaa agcagcatta ggcgtcttgt tgctgttgct tctcgtaagc tttgctcgat
    11521 tcgcctatta tctgttcttt gctaaaaaag cgtagattcc atatacggta ggtgttgcat
    11581 ctgccgtttt tttgtgtgaa aatggttgtt tgtaaaagga ggctttttta tggaaaaaat
    11641 tgccattatc ggtggcggga tcattggtat gaccctagcc agttacttag atacatcaaa
    11701 attcaatgtt gctttatttg atgaagggac aggacaggca actaaagcta gcgctgggat
    11761 tatctcccct tggttgtcga aacgcagaaa caaacaatgg tatcgtctgg ctaaagacgg
    11821 cgctgctttt ttccctaaac ttataaaaga tttccaactt gatcaaacga tttacgcaca
    11881 atcagggaca cttttgcttc gacctgaaaa agatttagct gaattggctg ttcttgccga
    11941 gaaacgaaaa gaagaagcgc cagaaattgg aaacatcgaa tggctttcac ctgaacaaac
    12001 atctcaagca cttccgttat tgaaaccagc agtttcactg cgtatcagtg gtggtggtcg
    12061 tctggatgga aaagcatatt tagaacatct tggtcagcgt ttagcacaaa aacaaatgga
    12121 gcagatccag gcaaaagtca cttcgcataa gaagagcgat tcttggctca tcaagggacc
    12181 gtttggagaa tacacagctg atcgtgtaat tttgacacct ggcccggcac ttaagccttt
    12241 attacaagaa ttaggctatg ctgcagatat acgtccgcaa aaagggcagc tcttagcatt
    12301 tcagacatct tataagatga gtcaagactg gcctgttgct atgcttgacg gagaagctga
    12361 tttcattcct ttcatggatg gaaagatcct tttaggtgct acccatgaaa acgatcaagg
    12421 ctgggatttg gctcctacta gcgaagctta taagggattg actaagagta cagaacagtt
    12481 cttgactgat ccagatcaga taaaaaactg gccatacgag ttccgtgtag gtacccgtgc
    12541 ttatacgtca gatttttccc catttttcgg cgtactgcca gatgatccaa gcttactggc
    12601 tgctagcggt ctaggctctt ctggcttgac cacaggtcct tatatcggct atctattagc
    12661 caacttctta aatactggtc attggcctac ggaagattat caaaaggaca tctccaccta
    12721 tattacgaaa aatccatcat agaaaaacag ctttttcaag taaggatccc gagcgatatt
    12781 gcgcatggat tacttcttga aaaagctgtt attttagttc aatttctgaa tcaaattctc
    12841 caaactttct tttgcttcat ctggcaagag atcttttcct atctgagctt caatgaatcg
    12901 taaacgaata tcaagtcgtt gtttcaccag atttttatag gacgtatcct caaaagaaac
    12961 aggaaaatct ggtataggta aatagtggat gtcttcaaat ggaccaaacg acttgaattc
    13021 tgccgtttgt tgcacgattc tttcaacgat tgacaatgtc gtttcaggtt tgattttttt
    13081 atcatcgaaa tatccagtat tcaggacata gcaggctgtt tgctgtttca aaaacaactc
    13141 tcgaaaagct tgatagtctt ccctaagagg atagacacgg aaaggattag caaatggttc
    13201 aatgactagc tcatctagct gtctttttgt agtgatattt tccgcgtctg atcgttttgt
    13261 tgctaatgtt gcaccaaaag acgctgctaa aaccgggtca ttgatcttga taattggcgg
    13321 aagcgaatca tctttcatga tccaaaaaac agcatcgatc ttttcgctaa gatgatcgac
    13381 tcggtcgggt gtcgcataac gtgatttgac tgtccgccca tttccgtttc gtatatctcc
    13441 tgttactagg actttttctc ctttacttgt acatgtcacg cccacattct gacaagtaag
    13501 gaaagaagaa atggccggat catcagacgg atagtcttgt gttttatcaa agtaagaagg
    13561 ttccaaggca gtagcaaaac cattttttcg agaaataacg aaagcatcgt catgcaagat
    13621 cgaaacagag tgaccttccg tatgttttgc taaggtaatc gttgattttc cagaaccgga
    13681 caacccaaat acagccatcg tataggtctg gtcattacta gcatattgtt tcatcccacc
    13741 gtggcaggca ataaaaccat tgcgatttcc caatgcccaa gcaagcgtca aagtcgcttt
    13801 ttttaattct ccaaagtaac gtaatcctag cacagccgct gtattatgga gagcatcaaa
    13861 caaaatgagt ccattgggaa atgtttcatg tgtccactcg ggatcacaaa agatataaag
    13921 atctccctca tcaaaggaaa cagacttttg ataagtcttt aagatcttcg aattcgctgg
    13981 ctgaaaattc agcaaataag aatacaaatt gttctcaaat ccttctggaa tcagcaaatg
    14041 actttgcaca gaaaattctt cagataggcc aacgattact tttgtatggt aaaactggcg
    14101 tttgcgactt tgatacacag cttctcttaa aattttctcg tatttgcttt gttccttgtc
    14161 taagtcctca aagatccgcc gagcacttgc tgttcttccc acaatgcttc catcattgaa
    14221 tactagtgtc ctgacatcag ctggtaaatc tagttcttca gcatgtgaga ttgttaaatc
    14281 tgtgatgatc gttcctggac tcccttttgc tagttgataa gctgtcttcc tgtcaaaaac
    14341 ttcatgaaca ttattaccgt aaaatgtcgt ttctacaatc gatcgaatac tggataacag
    14401 tggatttcca cttgtgattt cgtttaattc gagactctct tttgtactca tggctcctcc
    14461 tcattcccta aacaaaaaaa cgttttcttt attatacatt attcgagttt ttatttgtac
    14521 tgctgcgctg tgggaagcaa acgagttatt tttcacacaa aaaaaccgag aacttgaata
    14581 aacaagtttc tcggtttcat cattttcctt ttatcggctt agtaccagcc gtttgctaac
    14641 cagaatgttt tagcagcatc ccatgaacca taacgagatg ttacatattg ttctgctaca
    14701 cgttcttgat tggcagctga atagtcgccg tttaagtatg aagcatctaa ttgataacgg
    14761 ccgatgtaac gtccgttagt agctgtgtat gaaccgcctg attctttttg tgcgatccat
    14821 tcttttgcag agcttgaagt tggcgctgtt gcagcagctg gggcagcagg agctacttca
    14881 actgtttcaa caggtgcaac gtatgtatgt tcttgcgttg ctgtttcagt tgtagatgct
    14941 gtattttctg ttgttttgtt ttctgttgtt gctgaagaat catttgaagt tgggattgtt
    15001 aattgttcac caacataaat gcggttgatg tttgcgatcg aatttttttc agcaattgca
    15061 tcgatcattg agttgtctcc tgcaaatttt tgtgagatct tagataatga atcacctgat
    15121 tttactgtat aaacttcatc agcgtgagca tttgtagttc ctacaaacat tgcagtagca
    15181 ccagcagcaa aagttgtacc taaaacaatt ttcttaaatg aattcatatt aaactccttt
    15241 ttttctccgt tttttattct ttcgacgcta ttaactttat catttagaaa tatttcatag
    15301 gtaaaagaat catgacattt aatgacaaaa tgacgaatta tttaatattt gtaacattta
    15361 aacaaatatt tttttgatac aaaaccataa aaaccttgtt gtataagcaa agtaatcgtt
    15421 tttctatgtt tttttatttt tgaatgaaaa acgcagattc tgtaacattt actgcaataa
    15481 tccataaaaa aaagcaaaaa aatttttgat ttttatcaaa ttctcttaaa aaaatgtaaa
    15541 aaatacaaaa aaaccagtaa ttgttacaac aattactgga caaaaacttt gaataatgtt
    15601 aactattttt ttattttaac tttctccgca ataatttctg ggcatgttcc aattcgttta
    15661 taacgacttc ttctgtttct ttagctaata tttcatctaa tacatcaagc catttttccg
    15721 gttcttttgt tcctagacgt ccaatagccc aagctgctgt tcctctgatg acagggcgga
    15781 catctgttaa acattctgaa atctcaggca atgccgttcg atcacctaga ttagctaaag
    15841 caatcaatgc gtttctctgc aaaggtttct tcccacgcca tgaaccagct aaatgcccaa
    15901 attgctgttt gaagtcttta ttagacatcg aaagcattgg ctttaatttt ggatatactt
    15961 cgtctacttt tggttccatc tcttcatgaa aatgaaaatc ttttccttga ttgtaagggc
    16021 agactaactg gcagatatca catccataaa tgacatttcg cattttttta cgatattctt
    16081 ccggcatcat cccttttgtc tgagtttgat aagacaaaca tcgctgggca ttcattcttc
    16141 cgtcaccaag caatgctttt gtcggacaag cagtcacgca gcgcatacag tcaccgcaac
    16201 caaattctcc tggtttatca ggctcaaata caatattagt aacgatctca ccaagataga
    16261 caaatgaacc gaactcttca gtgatcaaca atccgtttcg tccaataaat cctaaaccag
    16321 ctcgctgtgc tacagcgaca tcgatcagtt ctccagtatc tacttgcgga gctagacgcc
    16381 attcctcttc tttttgccat ttttctgctc ttgtttggat gaattcaatc aatcggttca
    16441 aacggtctct gagtatatca tggtaatcga tcccccaaga agcacgagca aactgtccgc
    16501 gtttttcatc cctaggcact tcttcatgga tcctagtagg atacgcaagt gcaatggaaa
    16561 tgatcgattt cggctgatca aatgtcattt caggataaag acgctcatcg atatttggat
    16621 gttcaaagcc agaagtatgg ccagctgctt tttgttcttc caacgattct tttaatgaat
    16681 caaaaggttc cgccgtggtg aacccgattt tgtcaattcc taatcgtttg ctttcttgta
    16741 tgatttcttc ttttaatgtc atggtcttcc tcgcttgctg ttaacggctg tataacccat
    16801 aatatagttt ttcttttttc agctggacaa actggatctg ctgatcggca atcttctttt
    16861 cttccatcca tttttttctt gcagcaaata cttcccaata atttgttgaa attaattttc
    16921 ttttgttatc taatgcatta aaaaaattca atgaaactgg ttttgtactt aacagttcat
    16981 ggagccttac ctcttcccat ggcgaaaact cagacagatc gcgggaatac aatacttctt
    17041 catagagatt tttttgctgt gtgtacgtga atgtttgcgg gattttccca ggcctggcaa
    17101 tttctactag acgattataa aacatattca ttaatttgct gttggcaata aattgacttt
    17161 tataataggc cgactggatc tttttgatta ctccttctgc tttgatgact gaaaataatg
    17221 caggccatgc tttgacggtt atttcgtcgt tttgtttaac taatacgcca ggtatgaagc
    17281 cgactggaga aaggaacaca aaataaccga taccggtatt ttcatctaaa ggctgaaatt
    17341 catcaaacaa ccatttgcct atgtacagct cttcatctgg ttctgttgtc tcattttgat
    17401 ttgctatgaa taatttagct aattctgctt caagaaattg aaggtcttga tccttgtcgg
    17461 tattttcctg ctggctgatc aatcgaaaga cttcttcttt aatcgtatat ttatctttac
    17521 gtgtaaaatt catagccaca ccttccttcc ttactctaac tataacggaa tttcttcaaa
    17581 aaaggtatct gtacgccgaa aaacagcata atttttttca tatctcttat aaaaaatgca
    17641 aggcctgctc ctcaagctag accttgcact tttcagcttt cttttatttg tgacaaacct
    17701 tcatggatcg tttcaatatt ccatttcatc atctgatagt aagaatctcc ttgttctcct
    17761 tcttttgcta tggaatcagt gaacagttta tcatagattt tcaaacccgt ttcttttgct
    17821 acccgttcca tgcttcttga gtctacactg gtttccacga ataaaaccgg tacttctttt
    17881 gctcttatct gatcaatgat cgctttcatt tgatcaggcg taccttgact ttctgtattg
    17941 atctcccata tataagctgc tggcaaatca tatgctcgtg aaaaatactt gaatgcccct
    18001 tcacttgtta ctaataattt tttgttctct tcgatagaag caaaactttc cttcgcttgt
    18061 gtatctaatt cttttagttt ttccacatat gcttctgcat tttttttata tagtgtcgca
    18121 ttttctgcat ctttttcaga gaatatacgt gcgatttcct ccacatattt tattccgtta
    18181 gataggtcta gccaagcatg gggatctgct tttgtatgtt cttcaccgct agttaaataa
    18241 agaggttcta catttttgct aacagcaaaa taatcttttc cttcttcttt tttagccgtt
    18301 tccatcaagt tatcgaacca gctgttacct gtttcaagat tcaaaccgtt gtataaaata
    18361 acatccgcat cgcttgcctt tttgatgtct tctggtagta cttcatattc atgcggatct
    18421 gttccgactg gtacgatact gtggatatct atttgatctg ttccgacctc ttttgccatg
    18481 tccgccaaga tcgaattggt agccacgact gacaactttc ctttacttcc ttcatccgct
    18541 tggtcagaag cctgctttcc gcaaccggct aataccaaga aactaactgc caagattaaa
    18601 aagagtgatt tttttgtttt catctatctg cttcctttct gaaataaaat tccttttgtt
    18661 ggagaaaata aaaaagcaag gataaaaaat gcggtacatg ctaacacgat cgtagctcct
    18721 gatggccaat tgtaactata actgaaaaac acaccgacaa ctgcacttag cataccgatt
    18781 cctgcagctg taatgatcat tttcagtaaa tggttcgtta gcaagtaagc cgtggcggct
    18841 ggtgtgatca acatggcaat caccaagatt gttcctactg tctgtaaact gactacagcc
    18901 actaatgtca aaaagaacat caaaagataa tggatcagcg atgtgttcaa cccataagct
    18961 tttgccattg tcggatcgaa tgatgtgatc ttcaattctt tataaaagaa aaagacaaat
    19021 atcaagacga ttccactaac gagtgctgtc agcaacaaat cgctttccct aacagctaag
    19081 acattcccaa ataaaatatg atacaaatct gtcgcactct gggcatatga aatcaagata
    19141 atccctaatg caaaaaagga gctaaagaca attccaatcg ctgtatcatt tttcaatcgg
    19201 ctccgctgag tcacgaaacc aatcactgct gctgttagca tcccaaaagc agtggctcca
    19261 aagatgtaac taaaaccaaa catataagaa atggctacac ctggaagaac tgcgtgagag
    19321 atagcgtctc ccatcaaaga catccctcgt aaaataataa aagaaccgat gactccagaa
    19381 gcaagtccta caagcatgga agtgaccaaa gcgtattgca ggaattgata attcattaat
    19441 ccatcaataa aggattggat cattttttct ctcctccttt tactaaatgt ctgatgatct
    19501 caccataggc caattgaagg ttcttcgatg taaagacttc ttgtactgga ccggaagcga
    19561 tcagctgttt atttaaaaga ataacctcat cgaaatattc ttctacttta tgaagatcat
    19621 gatggacgat caaaatcgtt tttcctgaat tcttcaattc ctgcaagatg tcaaagatct
    19681 ttcgttcact taacgcatca atccctacga atggttcatc taaaaagatc cattctgctc
    19741 cttgggctag agctcttgca ataaaaactc tctgaagctg tccacccgat agttcgctga
    19801 tctgtctttt ggcatattct tccatcccta cttttttcaa agcttgtctt gcacgttctt
    19861 tttctttttt cccaggtctt tgtccaattc gtaaagatgg atatgttcct aaaagtacaa
    19921 cgcctaatac atcaattgga aaggaaagat ccaattcact tcgctgttcc acgtaggcta
    19981 tttttttacg gactgagttt accggctgtc cagaaaaggt gactttacca gtagtagctg
    20041 gtatcaactc tagcaaagat ttcataaatg ttgattttcc tgcaccgttt ggtccgataa
    20101 taccggtaat tttttgtgga tttatcgtca agttgatagt tttcaaaaca gttttccctt
    20161 gataagcggc tgaaaggtct tgaattacaa tggccgtacg ttccaaatct tacactcctt
    20221 tttaggttaa cctaactttt tatttaaata tagtttaact aaagtggaaa gcattttcaa
    20281 gtagaatgat gaaaaagttt ttttcgaatt ttcctcgcat tttatgaaaa ttttctgtag
    20341 aatcacatca agagttcaat aaggctaacc taataatgaa aaacatgtgt tgaaacgttt
    20401 gattattttt tcttgttgac tcaacaacga aaggagtttt tgtatggaag aagaaaagtt
    20461 aactcgaagt cttagtgccc gtcatatcca aatgatcgca ctaggtggaa cgatcggtgt
    20521 cggtctgttt atgggtgcct cctcaaccat acgctggaca gggccctcag tgatgggagc
    20581 ctatgcgatt gcagggttct ttttgtattt gattatgcgt gctttaggcg aaatgcttta
    20641 cgttgatcct tcgactggtt cttttgcaaa ttacgcgagc gagtacatcc atcctgtggc
    20701 tggctacttg accgcttgga gtaatatttt tcaatatatt gtcgtaggaa taagtgaagt
    20761 gattgctgta ggatcttata tgaattattg gtggcctgat ttgccggcaa ttattcccgg
    20821 gatcattgtc gtcttgtttc ttatgctggc aaatcttatt tctgtcaagg cgtttggcga
    20881 attagaattt tggttttcga tcatcaaagt cataacgatc attttgatga tcattgcagg
    20941 tcttggggta atcttatttg gatttggtaa tcatggtcag acagtaggga tttcaaatct
    21001 ttggaaaaat ggtggattct tcactggagg cgtcaaagga tttttctttg cattatcgat
    21061 cgttgttgct tcctatcaag gaatcgaact gattggaatg actgctggtg aagcagagaa
    21121 tcctaaaaag acgatcattg aagctgtcca gtccactatc ggtcgaatct tgatttttta
    21181 tattggtgct atttttatca ttgtgagtat ctatccgtgg aatcaattga gtgagattgg
    21241 ttcacctttt gtacaaactt tttctaaagt cggcattaca tttgctgcag gactgattaa
    21301 ttttgtcgtg attacagcgg cattatcagg ttgcaattca gggattttca gcgcaagtcg
    21361 tatggtctat acacttgcca tgaatggaaa gatgtctaaa aaatttctga aactttctcg
    21421 tcacggcgcg cctttttatc ctgtcgtagc aatctcaggt ggaatcttaa ttggtctgat
    21481 cttaaattat cttctaccaa tgttcatcaa ccagtcagaa aatattttcg ttttcgtata
    21541 cagctcaagt attttgcctg gtatggttcc ttgggtagtg attttgatca gcgagattcg
    21601 cttcaaaaag aagcacgcag ataaaatgca tgatcatcct tttaaaatgc cactatctcc
    21661 ttatacgaat tatgtgacac ttgctttttt agctatcgta ttgattttca tgtttatcaa
    21721 tcctgaaacg agaatctcat tgattattgg actcgttttc ttgctttaca tgacgatcca
    21781 ttactttgta cgcgaaaaaa gaaccggaaa ataaaaaaag aacgaagctt caccttagtg
    21841 gaagcttcgt tcttttttat tgcttttatc aattcaattt tagcgtctca ccgggagtca
    21901 ggaaataatt ctccatgctc atcccattca gcgacaagat tgtttctact ggtacgccag
    21961 ttcgttcggc tatttgattt ggaccttctc cttccaaaac tacggttgtc gcagcctgtg
    22021 aagtcgcgct gttggtatta gtttcagagg gatctgttgt gtcttgtgtt gttcgagctt
    22081 gcatttcaga agcttctacc gactctgccg tctcagaatc agaagatgtt gtgtcttgtg
    22141 tgcttgttga ctctgcttga agagaggcgc tagtctgcaa ataaatatcg gaaatcttag
    22201 ctacatgatt cgtataatta gccgataatt gattgatcaa agtatctaag tctacaccgt
    22261 ctttattttc tgctgcctga tacgctgcac gtaattttct gatcccttcg tcggagattg
    22321 cttgaagctc acgtgctttt tggttagcaa ctgctgataa accagctatg ccctcttgat
    22381 ttccctgaat ttctgtctgg tattcttcaa tcaatgcagg cgtcttttct tcgatctttt
    22441 tcgaataatc ttttacgatt gcttgaagtt gctctggcaa accatttgct gttttttctt
    22501 cagaagtttg tgtctctttt gttttagttg atgactcact tgtttgtttc gtctctgttt
    22561 tctttgtcgt ggtttccgtt atggtcgtac ttttcgcttc tgacgaattt tttccatgaa
    22621 aatatagacc cgcaactcct cctgctatga tcaaaaacac ggcaactgct gccccaatca
    22681 tgatcatccg cttacgagct gcctgttttt gctgtcttct tcgggtcatc cgaacatttt
    22741 ctccccactc attttcatca tacatttttt tcaccaccaa tttttatgta taatagcgtt
    22801 atcaaacgct tcatattctt attgtagcaa ataattgccg ctgtgcacat ttttatcttt
    22861 gttatttata agaaaatttc accagttgag atgattccaa gattgtccgt cgatttctcc
    22921 ttgcagctgc attgttcgtt cgtctatctc agccatcagt ttctttattt catataagag
    22981 cgcacggtct tgatattctg atttttcgct taattcatct aattgttgga tcagccaatc
    23041 atttgtcata atgaatttcc tttcatttct tgcagtgtaa aggtcaagtc ttcgatctgc
    23101 tcttttgcct cagtcagtgc ttctacgata tatgcttgtt tttcagattc ttcttcctgc
    23161 attttctgat tttcctgtac tctttgaata aaccagtcaa tccgctgagt cagcgatggt
    23221 ttgccttcca atgagagata ctgctgataa gcaattagct tctcccaacg tttttcctgg
    23281 gataaataca taaattgtgc taaaacgaat ggcggaagat aggtcatatg gaatttattt
    23341 gcgattcgct gatacggcct caaaaattcg gaaatcgtat attcttcttt tcctccagct
    23401 tggtattctt tttccgccac acctgttgtc aatacgattc ctagttcttt cccttttaat
    23461 acatgtgctg ctcgttccaa gacattatct tgccaaattt ttaaatgagc aggagaacta
    23521 taccagtaaa acggaaactg gaaaatgatc cgatcatgct gggccaagag ctgtagttca
    23581 gtctctatat ctatttttcc gtctggataa cttgattcca aatgatgcca agtagctggt
    23641 aaaccagcag aagcttcttt gaaaaattgc tgatttaaag attcttcgat cgttggatgg
    23701 ctaatgatga taagtgtacg catccctttt cctccttttt agtcttcgct ttacagtgta
    23761 gcataaccgc cacaagtttc ttttgccgat gcttgtcatt ttaaccagac taatcaggtt
    23821 gtccaagaaa ctgcggtttg tttttccaac tgttttttca aggtatccaa agcaatattc
    23881 ttaaaatttt cgtttttcat acgtttacga tagttcgtag ccgtttctcc ggtactcttt
    23941 ttgaacattc ggctaaatac gactagacta ttgaacccta cttgataggc aatactttcc
    24001 acggattcat ccgtcagaga aagaagaaac gcccctcgat tgatccgtac cccgatcaaa
    24061 tattccttga tactggtacc catatgattt ttgaatactc gcgacaaatg gctccgattg
    24121 accgctaaat gctgggcgat ttcctcaaca gacaattttt cagcataatg tgcctcgatg
    24181 tatttgactg tttcaacagc taaagaggaa tgaacctttt gtacaccacc gctgaccttt
    24241 ccgccatctt ttaaaaggac tgataaaaaa cggtaggtta atgctgttaa ctgtaattca
    24301 ttttccaagg tttcttccgt atctttcatg cattctaaaa taatgtcgat atatttttgt
    24361 atgtcagaag agaccatcgt gtattggtct tctctgaaaa gcgactgccg aatgatttct
    24421 tctgcagcac tcccaccaaa tgaaagccag caatacatcc acggatcttc tccatctgat
    24481 aagtaaaacg tcgagtctcc tggacgaatc aagaacagat cacctttttt caattggaat
    24541 tgttgatttt tcacatgata agatcctttg ccttccatca cgacatgcag gatgtaatca
    24601 ttgcgaatag caggaccaaa agaatgaaac ggcatcgttt tagagaaacc acaaaaatca
    24661 aaatacaatt ctttttctac ttgttgatgt tcctttttta aaaaaatcga ttgctccacg
    24721 tctatccctc cttactcctt tagtataatg caacaaaaag ttaaataaaa gtcacagaaa
    24781 tatattaaaa aggaagcgat ttcttgttaa gtttaagtca ttaaaagatc tttgttattc
    24841 gttgtaaccg gtttacttag tattatatat tgaacaggag aggaatacag attatgaaaa
    24901 gcaaaatgat ccaacgtgtg tcctacgctt taggcgcttt tggacacgac acattctatg
    24961 ttacattaag cacttatttt atggtattcg tgacaagcca gatgttcgca ggaacagata
    25021 aggcaacgaa tgcaaaaatg attgctacag ttacaagctt agttgtaggt atccgcttag
    25081 ttgaaattat ttttgatcct ttgattggtg gcatcatcga taatactcgt acaaaatacg
    25141 gtaaattcaa accatggtta gttatcggcg gcgttgttag ttccgtactc ttggtaacaa
    25201 tctttaccaa tttctttggc ttagctactc ataatacgac tttatttatc atattatttg
    25261 caatcgtttt catcttattg gatagttttt attcatttaa ggatatcgct ttttggtcaa
    25321 tgattccagc tttgagtacg gaaacaaagg aacgtgaaaa atttgctacg tttgctcgtt
    25381 tcggctcttc tctaggtgca aatggtacta ctctagtcgt tgtccctatc gttactttct
    25441 ttacctatct tgttactcat aaacatattg aaggcgcttc aggctggttc tggttcggtg
    25501 tgattgctgc tgtgatttca ggcggtactg cgattatcac tgccttgggc acaaaagaag
    25561 tcgatactgc gatccgtcag caaaatgaaa aagctgggat caaagatgtg ttcaaagcag
    25621 ttgctcaaaa tgatcagttg atgtggcttg cccttgctta tatcgcttat gcgattgcca
    25681 atgtagcaac aactgccgta ttattctact tcttcaaata tgtacttggc caaccaactg
    25741 aattttggat cgttggtcta gttgctgcct tacttggttt agtagctgtt ccactattcc
    25801 caatgcttac acgcgtcatc tctcgtcgct acgtttacct tggagggatc gcaatgatga
    25861 tttcttctta ctttttcttt acgatcgcag gttcaagttt gccaatcgtt atcatcgggc
    25921 tagtattgtt ctacttccct caacaattga ttttcttatc cgccttgatg acgatcacag
    25981 actctgttga atatggtcaa tggaaaaatg gtatccgtaa cgaagctgtt actctatcaa
    26041 ttcgcccttt actagataaa atcgctggtg ctttgtctaa cgggatcgta gggtttgtcg
    26101 ctatcgcttc tgggatgact ggtaatgcta ctgctgctga tatcactgct catggcgtaa
    26161 cgactttcaa agcttatgca ttctatgctc ctgctgcttt gatgattttc tccgctatta
    26221 tttttgcttg gaagattaca ttgacagaga aaaaacatgc acaaatcgtt gaggaattgg
    26281 aaaacaaatt ggctccagct gatacaatgg aagatgaact tcacgatgca gtagttcctt
    26341 cccattaaga aaggatcttg aaaatgaaga ttacagaaaa agattttggc caaggttatc
    26401 acttgataac cttggagaac aaaaacaagc tagcactttc tatctctgat ttaggtgcta
    26461 gaatcgtcag tttaaaatca aatgatcgag aattagtttt gggatttgat accgctgaag
    26521 aatatatcga aaaagatccg tatatcggtg cttctatcgg tcgcaccgca gggagaatcg
    26581 aaaatggccg cttttctctc aatggaaaaa cttaccaatt agccacagat ccaaaaactg
    26641 ggcataatct gcatggtggt gctcctggat ttgaattaaa aaaatggtct tatgtcattt
    26701 tgaatggcga aaatgaagct tctgtcattt ttactactac aagtcccgac ggagaacatg
    26761 gttttccagg tacaatggat gtggaaatcc gctatacttt gacacaagat aatatctggc
    26821 gagtgacctc tcgcggcacc agtgaccaag atactttatt caatccgaca aatcatgttt
    26881 acttcaactt gacgggagat gcttctcaat caatcgatca acatgagctt tggctcaata
    26941 gcgaagctta tgctcctttg cgaacagata gtattcctat aggggtaaaa gaaaatacta
    27001 caggaagtgc tttcgatttt caaataccta aaaaattagc gtccgttttt gctagtgatt
    27061 tggatcaaaa aaatcttgtt gacggaatcg atcatccatt tttcttaaaa gaaaccggct
    27121 tggataaaga agccgctcgc ttgactagcc ccgataaaag aatccaagta gatattgcta
    27181 cagatgcttc tagtgtggtt attttcactg caaatttcgg cacagaaaca ccagaaatgc
    27241 gcaaccgaaa actggcacat catggtggca tcacatttga gactcaaaca gctccaggtg
    27301 cagagcgctt ctcagcattt ggttcgattc atttaaaagc cggatcagta tttgaaacag
    27361 tgacagaatt caaaatcaaa acaagaaagg aataactcat catggaaatc aaaagaagct
    27421 taaacacaaa atttgccgaa acattcggac ctaaaaaaac tacacaatac ttctcaccag
    27481 gacgcatcaa tttgattggt gaacacacag attacaatgg aggccatgtc ttccccgctt
    27541 ccatcactta tggaacgcaa ggtgtcgcag cacctcgaga cgataataaa atattagttt
    27601 attccacaaa ctttgacgat atcggtgtca ttagttttac tttagatgag ctagaatatg
    27661 ataaaaaagc aaactgggca aattacgtaa aaggaatggt ccttaaatta aaagaagctg
    27721 gacactcaat cgatcatggg tttgagttgt tagtggaagg aacaatccct aatggtgcag
    27781 gactttccag tagcgcttca ttagaattat tggtaggtgt tgtattagaa gatctgtttg
    27841 atttaaaaac agatcgcttg gaactagtcc aaacaggtaa aaaagtagaa aatgaattca
    27901 tcggtgtcaa ttcaggtatc atggatcagt ttgccatcgg cttcggtgag ctagatcatg
    27961 caatcttatt agatacaaat acgctgaaat acgaaatggt cccagtgaaa ctagatggtt
    28021 atgcaatcgt catcatgaat acgaataagc ggcgggaatt ggcagattca aaatacaatg
    28081 aacgccgcag cgaatgcgaa gaagccttgg cacgtttgca aaaaactttg cctatctctt
    28141 ctttaggaga cttagatgaa gaagaatttg aatcaactat tgaccaaatc ggcgatgata
    28201 cattgatacg cagagctcgc catgccgttt ctgaaaatca gcggactttg aaggcaaaag
    28261 ctgaattaga agctgggaac ttagaagcat ttggtcaact gttaaatgat tctcaccact
    28321 ctcttcgcta tgattatgaa gtaactggga tcgaattaga tacactagta gatgctgctc
    28381 aaaaacaaga aggtgtctta ggtgcacgaa tgacaggagc tggatttggt ggctgtgcga
    28441 ttgctcttgt caaagaagaa aatatacctg ccttcaaaaa caatgtctat gatgaataca
    28501 tgaaagttgt cggctatgct ccggaatttt atgttgcaca cattggaaat gggacaacaa
    28561 agatcgatcc agaagctgtt catgtttgat aaaaaaatca acgatctcag ctaaaaacaa
    28621 atagataaaa ataacctctc agcaattttc aaatgtgagc cttttgctcg tattcgaaaa
    28681 ttgctgtttt ttattgacac agaaagagaa catgtgttct aattgtattg aagaggtgat
    28741 tgttatgtgg gcgaatcaaa atccggtatt tgtttatgaa aaagaacctt caagagatat
    28801 tttatgtatt gactgcaaat ctttttacgc ctccgtagag tgcgttgaaa aggatcttga
    28861 tccccttaca actaaattag tagtcatgtc ctatccgtcc gattcgacag aaacacgggg
    28921 tagcggatta atcttggctt ccagtcctgc agcaaaaaaa gcttacggca tcaccaatat
    28981 cagccgtgcc agagatcttc ccttccccta tccaagtgat ttatatattg ttgccccaag
    29041 gatggcctat tatatggaaa agaacagaga aatcaattct atctataaaa aatatgcaga
    29101 cgaagcgaac catcatgtct attccgtcga tgaaagcttc cttgatgtaa caaatagcat
    29161 ggcactcttt ggtaaaacaa atgcgtacga catggctaaa ctgatccata aagatgtgtt
    29221 tgagcagacc ggaatctaca cgactatagg aattggcgat aacccgctac ttgctaaact
    29281 agccttagac aatggctcaa aagacggaaa acaaatgttt gctgaatggc gttatgaaga
    29341 tgtaccagaa aagttatgga aaatctcaga tatcactgac ttttggggaa tcggcaaacg
    29401 aacagcaaaa cgtctgaaac aaatgggtat acattctgtt tatgatttag ctcacgcgga
    29461 ttattatcac ttgaaaagca agctaggggt catcggtact cagctttatg cccatgcttg
    29521 ggggatcgat cgaagttttt tgggacaaga atatacacca aaatcaaaaa gtatcggaaa
    29581 tagtcaaatc ctagatagag attatacaag acgagaagaa atcgagatcg ttatcaaaga
    29641 aatggccgat caagtcggca ctcgcttgag acgatctgca gcaaaaacac aagtagtcag
    29701 cttatgggta ggatactctt taggctatct tgatccaaat ggcaagaccg ggtttcacca
    29761 gcaaatgaaa atcgaagcga caaatgctag cagagatcta gcagatgctt tattgaccat
    29821 tttccaccag cattaccact accaggatat tcggcgtgta ggcgtgaact gttccgacct
    29881 cgtatacgcg acaggtttac agcttaacct ttttgaagat cctgaaaagc agataaatga
    29941 agcgaaagtt gattttgttg tcgatacgat tagaaaaaaa tacggctttc aatcaatcat
    30001 ccatgcgcat agtctcttgc aaggaggacg cgccatcgca cgtagttctc tcgttggcgg
    30061 gcatgcaggt ggtatgagtg gattagaagg tggaaaagat gagacggaca gcaaaaaaat
    30121 tcattgacta taacgagtat cgagatcggc catttggatt aaaatggggg actgcttttg
    30181 cgatggaaga actagtcaac ggtatcaaaa aaaatgaaga agaagcacgc aaacagcctc
    30241 ttcctaaaca acaaatgaca ttgcaagaaa tcgatagtat actgacagaa gcctttttat
    30301 ctcgtaaagc agtaatcatt cagctcaatt taaaagatga atttggaaga ctcttggatg
    30361 aggtcgaagg gcacttcatt ggtgaagcct atgaagatta ctttatgatt gaccatcagc
    30421 cgatattgtg ggaagacgta cggtatattg agttaaagga aacaaaaaaa tggtttgtga
    30481 catgagaggt tgtgacagaa gtgatcaact tcaaaaaata agaaaggatt tttcgaaaat
    30541 tgcttcttaa atttttgtgg aattttggct tatttttcga agaagcaact tctggaacaa
    30601 cgtatattag atatcagagg ttgtgaaaaa gtcgcttagt tttgagtaac aatccaaggc
    30661 gctgatttca caacctctgt ctatccatct attcggtaag attcatgcat gacgtcttct
    30721 ttatttagta tgtagagccc tttttcttct gaccattcaa cataaatcag ctgttttaca
    30781 tctgcatagc cttctttctt caagttctcc ataagccatg attcagtcaa ttgattggac
    30841 tgaagcactt tatgctgaat ttgcccttca tctacaagca ggatcgataa agctttgtct
    30901 tcatctgatt ttttcaatac actcatttga ccggcattct ctaggataac atgtttggca
    30961 ttttcaagag aaaagcattc ctgctgtctt aagattgctc gcaactgctc catctcgata
    31021 tggttatttg tcaactctgt catgttgatg acgccgtctt tgattagaac agatggctcg
    31081 cctttgaccc aacgattgac cttttcattt ttttggacga tacgttcgat accataaatc
    31141 attactgccc aaagcgcaat ggcaaatagg acatgcccta catggacatt gtcatcatag
    31201 gttgattctt ctaagatccc acctaaaaca agcgtataga ctaaatcaaa cggtgtgatt
    31261 tctgacatgg atttcttccc aagcaaacgt accactaata ataaaccgat caacccgaat
    31321 accagtttca ttgtaattga aaaaatcatt ttttctcccc ctaactatct gttaattaaa
    31381 ttatatatgc tttctcacga acacgcatgg aatatacaag gaagaaatgt atccttttac
    31441 taaaaaaagg actgtgacac tgtagtgacc cccaaaagtt agactttttt ggagtggaga
    31501 aatccactcc tttttttcat gctctaaaat gatattttta cacaaccgtt acggttgttt
    31561 tacgaaattg gacg
//
LOCUS       DAPBCF010000027        31314 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.027, whole genome shotgun sequence.
ACCESSION   DAPBCF010000027 DAPBCF010000000
VERSION     DAPBCF010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 31314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31314
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.027"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..137
                     /locus_tag="RD508_001587"
     CDS             <1..137
                     /locus_tag="RD508_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDT7736192.1"
                     /translation="VYNCFEELKSAIDSYIYYYNNERIKQKLNWQSPVQFRKTTATVV
                     "
     gene            complement(368..2440)
                     /locus_tag="RD508_001588"
     CDS             complement(368..2440)
                     /locus_tag="RD508_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDT7736193.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEEQKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKEMRINPDF
                     TIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKMLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(2373..2750)
                     /locus_tag="RD508_001589"
     CDS             complement(2373..2750)
                     /locus_tag="RD508_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HDT7736194.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEAEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESGKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(2879..3457)
                     /locus_tag="RD508_001590"
     CDS             complement(2879..3457)
                     /locus_tag="RD508_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7736195.1"
                     /translation="MRGNMKMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLEGIHETNQIILQIFEAFQLTKEEKVHRSRELCSMIHGYL
                     SLRFLGYFTKESTIDPEDSYFWMINDFIATLP"
     gene            3589..4881
                     /locus_tag="RD508_001591"
     CDS             3589..4881
                     /locus_tag="RD508_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDT7736196.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLAHQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNAAALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLMGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATDNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSISSGHSPSHRQ"
     gene            complement(4941..6059)
                     /locus_tag="RD508_001592"
     CDS             complement(4941..6059)
                     /locus_tag="RD508_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HDT7736197.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SEFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILER
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(6073..7494)
                     /gene="arcD"
                     /locus_tag="RD508_001593"
     CDS             complement(6073..7494)
                     /gene="arcD"
                     /locus_tag="RD508_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HDT7736198.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFAIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVAFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(7741..8862)
                     /gene="mnmA"
                     /locus_tag="RD508_001594"
     CDS             complement(7741..8862)
                     /gene="mnmA"
                     /locus_tag="RD508_001594"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDT7736199.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNHAEVVFD
                     EPVRAITPGQAVVFYDEMECLGGGLIDHAYQETKVLQYV"
     gene            9266..9865
                     /locus_tag="RD508_001595"
     CDS             9266..9865
                     /locus_tag="RD508_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDT7736200.1"
                     /translation="MNYFTSDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(10015..11288)
                     /gene="efmA"
                     /locus_tag="RD508_001596"
                     /pseudo
     CDS             complement(10015..11288)
                     /gene="efmA"
                     /locus_tag="RD508_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
     gene            complement(11559..11903)
                     /locus_tag="RD508_001597"
     CDS             complement(11559..11903)
                     /locus_tag="RD508_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HDT7736201.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(12040..13185)
                     /locus_tag="RD508_001598"
     CDS             complement(12040..13185)
                     /locus_tag="RD508_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDT7736202.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSCQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLEQLVRAVKK"
     gene            complement(13365..14339)
                     /locus_tag="RD508_001599"
     CDS             complement(13365..14339)
                     /locus_tag="RD508_001599"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDT7736203.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLTIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(14419..15294)
                     /locus_tag="RD508_001600"
     CDS             complement(14419..15294)
                     /locus_tag="RD508_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HDT7736204.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELTNCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            15424..17331
                     /locus_tag="RD508_001601"
     CDS             15424..17331
                     /locus_tag="RD508_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HDT7736205.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIQYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAIYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(17872..21138)
                     /locus_tag="RD508_001602"
     CDS             complement(17872..21138)
                     /locus_tag="RD508_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HDT7736206.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEGNAHV
                     NIEGMSTMEEVPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPIRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNQATGEVLENAKDLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEQYVEM
                     ASYETKEILHTVDYRKPNYSTVYVTPEGSDTGNGSRQNPLSLTQALRYAYAGQTIVLA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWVLR
                     GFDVTNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTVSKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTVKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIDVVVYVMKQRKK
                     "
     gene            complement(21409..21954)
                     /locus_tag="RD508_001603"
     CDS             complement(21409..21954)
                     /locus_tag="RD508_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7736207.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(21966..22658)
                     /locus_tag="RD508_001604"
     CDS             complement(21966..22658)
                     /locus_tag="RD508_001604"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDT7736208.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYKPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSQDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(22677..22961)
                     /locus_tag="RD508_001605"
     CDS             complement(22677..22961)
                     /locus_tag="RD508_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736209.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(22974..23537)
                     /locus_tag="RD508_001606"
     CDS             complement(22974..23537)
                     /locus_tag="RD508_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDT7736210.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            23764..24414
                     /locus_tag="RD508_001607"
     CDS             23764..24414
                     /locus_tag="RD508_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HDT7736211.1"
                     /translation="MIKRNWPWLLALVLLFLFGFSFVLGLLLIGVVLVLWGLFGSRRK
                     KGKQEEIPALTNELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAKLKAI
                     DLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIKNKQT
                     YEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQKD"
     gene            24538..25734
                     /locus_tag="RD508_001608"
     CDS             24538..25734
                     /locus_tag="RD508_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDT7736212.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(25835..27211)
                     /locus_tag="RD508_001609"
     CDS             complement(25835..27211)
                     /locus_tag="RD508_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7736213.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSFSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIISILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(27248..28114)
                     /locus_tag="RD508_001610"
     CDS             complement(27248..28114)
                     /locus_tag="RD508_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HDT7736214.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(28203..29228)
                     /locus_tag="RD508_001611"
     CDS             complement(28203..29228)
                     /locus_tag="RD508_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7736215.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYRLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(29246..29920)
                     /locus_tag="RD508_001612"
     CDS             complement(29246..29920)
                     /locus_tag="RD508_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7736216.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKP
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(30101..30997)
                     /locus_tag="RD508_001613"
     CDS             complement(30101..30997)
                     /locus_tag="RD508_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7736217.1"
                     /translation="MKKRTGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     RNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYWKFKRQKQLRKNNRS"
     gene            complement(31071..31196)
                     /locus_tag="RD508_001614"
     CDS             complement(31071..31196)
                     /locus_tag="RD508_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7736218.1"
                     /translation="MKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKFKMKSEV"
BASE COUNT         9081 a         6688 c         5588 g         9957 t
ORIGIN      
        1 aagtttataa ctgtttcgag gaattaaaat cagccatcga tagctatatc tattactaca
       61 ataatgaacg gataaaacag aaattaaact ggcaaagtcc cgtccaattt cgtaaaacaa
      121 ccgcaacggt tgtgtaaaaa tatcatttta gagcatgaaa aaaggagtgg atttctccac
      181 tccaaaaaag tctaactttt gggggtcact acattgtcac agtccttttt tccgaataaa
      241 tggtgttcca gaagtagctt cttcggaaat aagccgaaat ttcacaaaaa tttgagaagc
      301 aattttcgta aattccttct tatttcttga agctgaccac ttctatcaca acctctttca
      361 tatcttatta cttcttcatt gctgctttta gtgctgctgc taatgggctt tcttctggtt
      421 cttctgcttg tgcatatttt ttcagcaagc gtcgttcttc atgtttggtc attttcttct
      481 tctgctcttt tttatcaagc attttttctg tcgttccatc gtatttacaa cggaaataag
      541 caccgttttt accttcgatg atttccattt tccggtgaca ttgcgggcat cgatgattag
      601 agacttttgg atcttttctt ctgcggtagt tgcaatctga attggtgcag acatagattt
      661 tgccgtcacg tgtgtttttc tcgcgcagat tggccccaca ttctgggcat ttcttttggg
      721 taatcgagaa atcttgatat tcttgtttgc ttgatttgat ctcattcacc aagcgttttg
      781 tttctttttc gattccattc aagaaggttc ctgcttgttt ctttcctgca gcaatagctt
      841 caaggtcttt ttcccagctt tctgtcaaat ctggtgttac taaagaggga tttaccaata
      901 ctaataattg cttaccttta ggagatactt gcagtccttg aggggtacgt tccatcagtt
      961 cagatttgat tagtttctcg ataatctctg cacgcgtagc tggggttccc agactgtatt
     1021 tttccatttg accaagcaag cttgcttctg acaatggttt aggcggtgca gatagttctt
     1081 ttttgatggt gaaatcggga ttgattctca tttctttttc ccatttgact gtttccgtct
     1141 cagtttcagt ttcgcctttc catcctgctt ggacgacacg attttgccga aaaatgaatc
     1201 gttctttacc aaattcaacc gtaacttttg tttggctgac tttatggggt tgagcaaaca
     1261 gtcctaaaaa acgagagaca atcatttgat agattttttg ctcttcatta cttaattttt
     1321 cataacgtgc tctgttttca gttggcaaaa gtgcatggtg atcggtcact ttactgtctt
     1381 ggaatacttt tgtctgttgg acgatggctc cgtttttcaa atactgcttg acctcaggag
     1441 caaagtcgct gactgcttgc aatcgttctt tcatcgtact tttcatgtca tttgtcagat
     1501 atttgctgtc tgtacgcgga taagtaacga tcttatgggt ctcatacaaa ctttgtacaa
     1561 gacttaatgt tttctttgca gaatagccat agcgttgatt ggcttctctt tggatctctg
     1621 ttaaatcata aggcaatggc gcagattccg tttttaattt ttcttggact tctgtgacag
     1681 ttcctttgct tgtactgatc aattgaacaa gtttttgtgc ttcttcttgt gtttttaaag
     1741 caaattgatt tttttgaagc attttggctt gttcttttcc agcttgcaac gtgatcgtga
     1801 aatacgtttg tggacggaac tgctcgattt tcttttcttg gtctctcact aatgctagtg
     1861 tcggtgtctg cacacggcct gctgataaat tatccgcgta cttcacagtt aaggctctgg
     1921 tcacattcaa tcctaccagc cagtccgctt ttgcccgggc aagagcagat tcatacaatg
     1981 catcatattc tttcgcaggt cttagttgct tgaatccagt tttgattgct ttatctgttt
     2041 gagaagagat ccataaccgc ttcactggtt tattgaaatg cacatactct aagatccagc
     2101 gagcaacaag ttccccttct cttccggcat ctgtcgcaat gactgcttct gagacatctt
     2161 ttcgctgagc cagctgcttg attgctttta attgatgtcc tgttttagga agtggtttga
     2221 ttcctagttt tttagggatc attggcaacg tgtccatttg ccagctctgc cattccttat
     2281 tcagatcttc cggcattttc aatcctaata aatgaccaag ggcccaagta acgatcacct
     2341 tgggtccttc ataataattt ttgtgctttt gattagcacc aagcaccttg cttaggtctt
     2401 tcgcaacgct tggtttttcc gctagaatta gttgtttcat aaaattcctt tccgctttct
     2461 actgtgatgg gctgatgatt tttcaacaac gcaagtcctt tgtattgctg taaatcatcg
     2521 tcacactctt cacaccagcg ctcatctccg tcattccaaa aggcgctgag aaagttactt
     2581 tttgcattga tatattcata attttgatgg atttcgttcc attgtttttc gtacgcttgt
     2641 cgtgcttctt cgaaagactc gaatgtttct tctgcttcaa tatcttcttc ccagtcttca
     2701 aaaaaccacc aaggctcatt gtccccgaac atggtaatta cttgatacat actcgtgctc
     2761 cttctttcag cttttctaga cttatcttag tcacttttca agaaagttgc aagaattttc
     2821 tcttataaaa ggatcattta atgaacatct tgaaaatgat ataaatgaat ctgattgttt
     2881 aaggcaaagt agcgataaag tcattgatca tccaaaaata gctgtcctct ggatcgattg
     2941 tcgattcttt tgtaaagtat cctaaaaaac gcaaggaaag atagccgtgg atcatactac
     3001 ataattctct gcttcggtgg actttttctt ctttcgttaa ttgaaaagcc tcaaagatct
     3061 gcaaaatgat ctggttcgtt tcatggattc cctctaataa aactgcttca ttggtgtggg
     3121 gcacactgat cagtaactca tacactgctt gatttgaaaa agcaaaggat cgataagttt
     3181 ctgcatagat ctgcagtgct tcctgaccac tttttcccac aagagcccga cgcagctggt
     3241 cattaagttc ctgcagaagt ttcgctgtta gcgctgtttt gacatcacga atatttttga
     3301 aatggttata cagcgaggga gccttgatat ccaagcgttt tgctaaatgc tgaaaggtta
     3361 tttgctgaac atccatctct tctgctagtt ctcgaaagca gtcgatgatt ttctcttgag
     3421 acagatttct ttttttcatt ttcatgtttc ctctcataaa ataaatcctt cactctttca
     3481 gtttaccacg aaaaagaaag agaaaaaaga gactttcatt gataaactac atattgtagt
     3541 ttataacaaa aagatgtaga tgaaaatttt cagaaagaag gagtctaatt ggctgcaaga
     3601 ataaaggaaa aattatttag gaaaagagaa acttgggaac aaaacttgtt tgtcttatgg
     3661 tttggaacat ttatggctgg tatcggattt agtttagtca tgccttttat gtcactttac
     3721 atagatacgt taggtaatta tagtacgtca caattgaact tttggagcgg attgactttt
     3781 tcatctactt tcttggtgac tacgctgatc tctccttggt ggggaaaatt agcccaccaa
     3841 aaaggaagaa aattgatgct gttgcgtgct tcattaggaa tggcaatcgt catttctttg
     3901 atgggttgcg tgactagtgt gtatcaatta gtcgcattgc gtctgcttca agggattttt
     3961 tctggttata tcagtaatgc cgctgccctt gtcgcaactg ggacgccaaa agaaaaaagt
     4021 ggtcaagttc ttggaacctt agcaactggt tctgttacag gaacattact tggaccgctt
     4081 cttggcggga tctctgcttc agcgtttggc tatcgcccta cctttttcat tacagggatc
     4141 atcttatttt tcgtcttctt gttgagtctg tttttcgtcc atgaaaaatt tgtcccagtg
     4201 aaaaaagaaa acatggtttc tgccaaacag attttcaaag acttgaaata tccacacgtc
     4261 gtcatcggta tgttcgtcac aacgatgatc atccaagcat ccaacaattc cattagtcca
     4321 atcatcagtc tgtacattcg ccaattgctg catggacatg ggaatgttac gttgatcagc
     4381 ggaatcatcg cttcgatacc tgggattgcc actttgatag ccgctccaag atttggtcgc
     4441 ttaggtgaca agattgggag tgaaagaata cttgcgattg gtttgggttt tgcgattctg
     4501 gtttatatcc caatggcatt cgtcacgaat gtttggcaat tagctgcctt acgttttttg
     4561 atgggtatct ctgatgcttg tctgctccct gctgtccaag cattgatcac aaaatattct
     4621 cctcatcaag ctgctggacg gatcttcagt tataaccaat ctttccaagc aactgataac
     4681 gtagtagggc ctatgatcgg ctccagtgtt tctagtgcat ttggttatcg tggcgtcttt
     4741 ctttcgactt ctcttcttgt tttggtcaac ttcttgcttg tacgacacaa tacacaagag
     4801 atccatcagc aagaaactgc agaagaaaaa gcttcaggag tctccatatc ttcagggcac
     4861 tctccttctc atagacaata agcgtaaatg aaaaacactg cttgaacagt tgtcacagac
     4921 tgtccttgca gtgtttttgt ttaggcctgt tttttcaaga actcagataa gaggaataat
     4981 cccttttcca aggtttcttt tttacaacag taacctagtc gggcatgctt cggtaaatca
     5041 aaggcacttc ctggtactaa tagtactcct gtttcttcta ataaattgat acaaaatgtc
     5101 tggtcatctt cttcgatggc taatttaatg aaagaagtag agacgtaatt gggagcgaca
     5161 agttcaactt tcggttcatt ggctacccat tgttttaaaa tcacaaggtt ctctgtaatg
     5221 atctttttgt ttcgctccaa tattttttct ttattcttca atgcatgtac agcaagatca
     5281 tctgacagga ctccgccgca aatcatcgtg tagtctcgat actttcgaaa aacttctgcc
     5341 aactcaggtc cagtagctgt ccagccaata cgaatacctg gaatggagta ggttttggat
     5401 agggaattgg ttgctatacc tttttcatag acatctacga tcgacaagaa ttcaccttta
     5461 tccgttaaag gcgcatatac ttcatctatc aatacatatg catctactgt acgagcaatt
     5521 tctgcgattt tttctaaagt tttccgatct agcaatgtgc ctgtaggatt gtttgcacta
     5581 ttcaaacaga tgatttttgt ttcaggtttg actaaggctt ctagctgttc taaatcaaac
     5641 tgccaatctt cttcttcctt caaatgaaca aagtcaacag cggcacctaa agatttgggg
     5701 atgtcatata attgctgata agtaggaagc atcgaaacaa catggtctcc tgcttccact
     5761 aacgcgtata gagctaaaag attagcacca gtcgctccat tcgtttgtaa gatgttttcc
     5821 ggatcgacgg tttgataaag agaagcgact tcttgtttga aaacatctga tccttcgatc
     5881 cagccatagt ccaatggttc gtttttgcgt ttttcgaaaa attcacttac gctagtccca
     5941 tctaagccaa cgagttcgtc taatgtcaat gcttcgatcg agctttgtgc aatatcatat
     6001 accgctttct tttcccattt atttagccat tcttctacac cgaaatttgc gattttcatg
     6061 tttctttccc ccttatatct tgatccagcc tacagcaagc aacccgattg aaagcagtgc
     6121 ggccacacaa atcagcccaa tcattacttt ttcttttccc gtaatttgat gtttggtttc
     6181 acgacaagcg atccagtaga agcaaaaacc aggaagatag gcaatactac ataaaaggac
     6241 ataagaaaat cctgctaaaa tgatgcccat caattcaaaa gctacagcaa tcccaccgat
     6301 cactacttgt tttttgattc cttcttttaa agaaaactgg acttgataga tcccgacaag
     6361 tagataacaa atcaaaattg ccgctgtaca taaagaatag gcaaattgat aggcataatc
     6421 agtaactaag aaagtcaata agaatagatt agtcaagatt gcagtaacaa ctaacgaata
     6481 agttggggca ttttttttat tcgtttttcc ccaacctttc ggcaacagac cgtctcgagc
     6541 catcaacatc gttgtttctg ctgggagcat cgtccaagac aaccaagaac caatgatcga
     6601 aataatcaag ccgatattga tcagcgctgc tccccaattt cccacgattc cttttaaaat
     6661 atttgccata gcaggttgtg aaatagttgc taactcttct tgagataaga cgccgtatgg
     6721 caagatcgaa gcaaggatat agataaacaa taaacaaagc agaccaatga tcgatgcttg
     6781 ctgggcttct gaacgtttct tcgcgcggtt ggctaaaaca cttgcgcctt cgatccctac
     6841 aaagacccac atcataacca tcaaacaacc tttaatctgc aaccagatcg ttccttgctg
     6901 ccctgttcca ttcactagat tatcagatac gttaccccaa aaatcagcag tgaatatatt
     6961 cactttaaat gcgataaata caaatattaa aaataggaat aatggcacta atttacagat
     7021 cgtcacgatt gtattgatga cgctcgctcc ttcaactcca ttgtttacta ataaagtcag
     7081 accccaaata aaaatacttg caaataaaat agaaggaaca ttttgtccac ctttgaatat
     7141 cgcgaaaaat tctcccatgg cgctcatcag catcgttgca aaagcaacat ttcccagcca
     7201 cgcagacaac cagtaacccc aaccactgat gaagccacct aatttaccaa atgaagcttc
     7261 cgcgtaaccg aaaataccac catctagatc tggacgtttt tctcctaaat gattcagcga
     7321 taataccaaa gctaaaatac caatcccaac gattatccat gaaaggatcg ctggccctgg
     7381 agctgcagaa ctagccagat cacttgtgat cccaaacaca ccgcttccga ttgacgaact
     7441 gacaaccaga gcaaccagtc cccatttgct aatacccgtt gatttctttt ccatttccat
     7501 caccctcact tataaaattg aacaaatcac ttgcaaaaga tttccttcta ttttgcaact
     7561 gctcttgctt aacaaaaagc aactttattc atattatcgg atattatgaa ctttttacac
     7621 aagtatttca agtataaaat gaataaaaat taattttatt gcaaaaaaaa cagctatgct
     7681 atccaaaaga aaaggtgttt cttttgttag ccatagctgt tttgattcat ttaatatcgc
     7741 ttaaacgtat tgtaaaactt ttgtttcttg atatgcgtgg tcgatcaaac caccacccag
     7801 acattccatt tcatcataaa atacaactgc ttgtccagga gtgattgcac gtacaggttc
     7861 gtcgaatacg acttctgcat gattatcatc caataagcga actgtcacag gaacgtcttg
     7921 ctgacgataa cggaatttcg ctgtacactt gaattctttt ggcattggtt cattcgtcgt
     7981 aaagtggatt tcacttgcat ccaagcttgt ggcatacaat gcaggatgat ggaacccttg
     8041 ccccacatat aatgtgtttg tcgctagatc ttttcctaca acaaaccagg gttcttgcga
     8101 atctcctccg ccaccgatcc ctagtccttg acgttgacca atcgtataat acatcaagcc
     8161 agcatgttgc cctttgactt caccatcaag agtgaccata tttccttttt ttgctggcag
     8221 atagttgctc aaaaattgtt tgaagttctt ttcaccaata aaacagattc ccgttgaatc
     8281 ttttttctta gcagtcgcaa ggcctgcgcg ttcagcaatt gcccgtactt ctgatttttc
     8341 catgccgcct agagggaaca tcgtttttga aagctgttct tgtgataatt ggctaaggaa
     8401 gtaagtttga tctttattat tgtctactcc acgaagcatg tggaccacgc cgttttcatc
     8461 gcgagtgact tgcgcataat gtccagtagc tacataatcg gcgccaagat ccattgcata
     8521 atccaagaat gctttgaatt tgatttcttt gttgcacatc acgtctgggt taggtgtacg
     8581 tcctgcgcgg tattcggcta ggaaatattc aaatacacga tcccaatatt ctttttcaaa
     8641 attcacagaa taataaggaa tcccgatttg agcagctact ttcgctacat ccttataatc
     8701 ttccgtggcc gtgcatacac cgttttcgtc cgtgtcatcc caatttttca tgaatattcc
     8761 gatcacgtcg tatccttgtt cctttaacaa aagtgctgtt acagatgagt cgacaccgcc
     8821 gctcatccct acgacaacgc gtgttttgct gttgtctgtc atgatatcac catcatttca
     8881 attagattct gaaacatcta cgagttgaag gtcgcaactt ttcagtattt tacattatac
     8941 gtcatatttc tgaaaatttc atcccttaat tatcaagtcg taaaaatact gttctactgg
     9001 acctattcag tacacaaaca tgatagtcaa ccaaaaaatc actcatcttt tgagcattcg
     9061 atataaaaaa ttggcatact cataaaaagg gccagccttt cggcaataag gaataatttt
     9121 ataaattgtg aaaaactatt tttcaaaatt gcttcttatc gcttaaagct acacgtctca
     9181 tttacaacct tttcttttta gatgttatga gttgctcaga taagtgattt tgtttactct
     9241 aagaaaaaag ggaggcaaaa gatacatgaa ttactttacc agtgatatgc actttttcca
     9301 tgaacgctta ttaggaaaaa acgactttgc tccgcggctc tttgcaaatg tggatgaaat
     9361 gaaccaacag ttgatcacta gctggaatgc agtaataaaa gaaaccgacc atgtttatca
     9421 tctaggcgac cttgctatgc atccgcaata tgaaaaagca aatgcagaaa ttttggaact
     9481 ggtcactcaa ctgcaaggaa caatccactt gatcaaaggg aaccatgaca gtcgcgcttt
     9541 tttccgttat ttagaaaaaa atgatcctag gcttactgac ggaagtccca aattttattt
     9601 ttatgatgta ggtgccatcg ttaaattcga ccatcaacaa tattacttga ctcattatcc
     9661 gatgttgctc gggcctaacg acactatccg caatcttcat ggacatatcc atcattacag
     9721 cgtacctatc gagaacgatg tcaatgtagg cgtagacgca ccggaaaggg aactcttaaa
     9781 ggaaaaacta ccatttggca ctccgttatc tgagcaacaa atcaaagaaa tctatgaagc
     9841 aaagaggaag tacgataggt cgtgaaaaaa ctgccctata tcaagtatta aacaaataaa
     9901 gataattact catatttttc atttgagtag gcttattgcc acaggaacat taggatcaga
     9961 aatggagttg taacaagact tctgtcacaa ctccattcca tactattcgt ctttttactc
    10021 atggtgttct tttaccaatt ttttctgtaa ttctttatca taatttcgag cagctgacgt
    10081 taaaaataaa acgattccgc ataataaaat cccgattcca gaaaacaaga acattttttc
    10141 tacccctaaa cgatcagcta atggtcctgc aaataataat ccaattggac ctgccaggtt
    10201 catcaaagag ttgaagttcc ctaagacacg acctaaaaca ttcgattcat aactctgctg
    10261 gatcattgcc atcagcagtg tattgaaata tggcgttgca caacctgctc ctgcattcaa
    10321 gataagaaag tacaagaacc cttgactatc gtttggaacc aatccgcttg caccgatcgt
    10381 caggcccata atgatgtagg ctataataat aggtttcatt cggtctttcc atgttcctat
    10441 aaaactgatc agtgcaccgc ctaagagcat tccgactgcg tagactactt ccactgctcc
    10501 cgcctgtcca acggaaccac caaagtaatc tagcgtcatc aatggataca gactgattgc
    10561 tggcatgaac aacagcatca caaatgcacc attgatcgtt atgtaccata accctttgtt
    10621 atccatcaat tgctgcagcc caaattttgc atctttaaaa atagtaagcg gaacttccaa
    10681 tatttcagga gaaacttttg ggatcttcac aaaaatcaat aagccgacac caaaaactgc
    10741 ccccaataca tctaataaaa taaggtaatt gacaggaacg actgaaaaca aagccgcacc
    10801 tagagctggc gcaatgatga aattcgctga ttggaccatt cctaactgtc cattcgtcct
    10861 tgttatgtga gaagatggaa cgattgtcgg cataatcgac tgatcgttgg catttggaat
    10921 gtttgtgcga ccgaacgcat aaacaaagac acaaaaacta gccaaatcgg gaaggattct
    10981 gaaatcgttc cgactactgc taaaataagc gcgaaaatcg ctacaataat atccgtgaca
    11041 atcaaaagag cttttttatc ccagcgatcc actagcggtt ctacaaatgg gcttagtaaa
    11101 accatgggaa tcattcctag taaagtagca aaactcaaaa ttgtcgccga accggtttct
    11161 cttgtcaaat accagatgat cgcatattgg acgaccatac tagtgattcc tgacaaaaac
    11221 tgtcccgata aaaagaacaa ataatttctc ttccaattcg ttaaaacgac cgactgttca
    11281 ttttccataa acatccctct tttctttttc attttgtata gcgtttgcac aacaatcatt
    11341 atacgggatt cttttttcaa aaaatacctt tttccctaaa taacaatcgt ttcaatttaa
    11401 atttctttac ttagaaacaa taaatcagca aaatattaaa aataacaaca tgtgttaaat
    11461 ttaaaaataa aaaagacaac taatttgcgt cgtccttaca aagttagtca tctaacaata
    11521 ggccgtttca aaactagttg tctttttata tccacagatc attcgacttt ttcgaataac
    11581 ccacggctaa tcatcccatc catcagaaaa taaaatttat cttggctcat tttctgtttt
    11641 ggatctttga aaatattgac tgctttcaat ccatttgctg tagtgatcga cattttcaat
    11701 gtttgaatat cttttgatac agtgattttt aatttgaatc cttctttgct ttgcggcgtg
    11761 gcatctaatg gtcggatcaa ttgataattg cctccgtttg tttctgtaaa tccattatcg
    11821 cgcaatgtat atctttttgc atcaggatgc aaacgatagc taattggtgc gcccagtacc
    11881 gttgctgttg tttcaaatgc catgattttc acctcgataa aattagtttc tctttattat
    11941 aaaagtttat cctgattttt actaggtttt tcagttaagt tccctaaaaa atgaaggcgt
    12001 tctctcagac atctgttcat ataagaatga cttcactagt tattttttga cagcacgaac
    12061 taattgttca aggaaatact ggatgtcgtc ttcggtattt cccaaaccaa agctgatacg
    12121 gatggattct tttagtatcg gtgtatcttc tccatacatt gcttctaata cgtgtgaagg
    12181 ctcgatatta cctgctgtac aagctgaacc agtagaaata gcgaccccat taagatcaag
    12241 cttcatcagt agcaaatcat ttgcttcgcc aattaagcga agattcaaca catgagggag
    12301 tttattcgtt aaatcaccat ttacttgata agggatttcg tttgcttcta atgtatcaag
    12361 aatcaattgc tggaatcctt tatatttgtt gttacgtgct tcacgttctt caggtgacag
    12421 cagttcaact gcttttgcca taccccagat ccctgctaaa ttttctgtac ctgcacgccg
    12481 cttttcttcc tgctccccgc ctaaaagcaa tgcagggata tttactccgt ctcgtttata
    12541 taagaaaccg acgccttttg gcccattgat tttatgagca gagatactta ataaatcgat
    12601 tcctaattct tctggatgga tcgtttggtt tccgtacgct tgtaccgcat ctgtatggaa
    12661 ataagctgga tgatccgcta aaagttcacc gatttctttg attggcatca aatttccgat
    12721 ctcattgttc ccatacatca cagagaccaa gatcgtatct tctcgtaacg cttttttgac
    12781 ctcttcgatc gacagattcc ctttttcatc tacaggcaga tatgtaacgt caaacccctt
    12841 tgtctctaaa tatttcatgg tattaagaac agcaggatgt tcgatagctg tagtgattag
    12901 atgtctgcct tctttttgac acgagaacgc tgtttctaag atagctgtat tatccccttc
    12961 tgttccccca ctgttaaaga tgatctcgtg aggttttgct tgcagactgt ctgcaatgat
    13021 ttgtcttgct gtttccaatt tttcatgcgc gtggcgacca aatccatgta tgcttgaagg
    13081 atttccaaac gtgtcttgca tgattgccgt catcgcttca attacttgtg gatgcatggg
    13141 ggtagttgcc gcatgatcca gataaatagt tttcacttca ttcatccctt ccaaattatt
    13201 gctaggcaca ttctagcata aaatagcgaa caaaccaaag aagagctcat ttttgtctag
    13261 aggacgtttc atgggcatag aaaaaaggag ctatgacaaa agtcttgtcg cagctccttg
    13321 aagctgctca cttgtgtcac aacttctttc cctctttttt ttgtttattc gaattctttt
    13381 tcttccagac ggaataacgg actcatcggt gtattttcat ggatgcgttt gaccgcttct
    13441 cccattaatt ctgaacatgt aacgattgtt aagttttctg gatgacgatt ttcttctgtg
    13501 aaaacagaat cagtgataca aatatctttg attggtgcat tgtctaaaat acttttcgca
    13561 tgatcggaca ataatccatg tgacgcacag gcatatactt cttttgcgcc gttttctttt
    13621 aatacatttg ctgctcgtgc aagcgttgct cctgtgttca agatatcatc taccatgata
    13681 catgtctttc cttgaacatc accgatcaca taaccaccct cagttgaagc atcatctgca
    13741 tgatctacga tggttaatgt gctgttcaaa tattctgaaa gactacgtgc acgctgaaca
    13801 ccgctgtttt ttggcgaaac aactacgatg tcatctcccg tcagacctaa ttgacggtaa
    13861 taatgagcaa acaacggcat cgtaaataaa ttatctacag gaatatcaaa gaatccttgt
    13921 acttgaaccg tgtgcagatc taaagtcagt actcgagttg cccctgcttc ttcgatcaag
    13981 ttagcgatca atttcgcagt gatcggttca tgaggtttcg ccgtgcggtc ttgcctagca
    14041 tacccatagt aaggcaatac gacattgatc gttttcgcac ttgctcgctt cattgcatcg
    14101 atcatgatca gtagttccat atagtagtca ttgacaggtg cattcgttga ttgaacgata
    14161 tacacatgat cccctcgaat actttcttcg atattgatgg aaatctcgcc atcactaaat
    14221 tgcttcacga cgcttttacc taattctgtt ccgaacactt tcgcgatttt ttcagctaat
    14281 ggacggttgc cattcaaact aaaaatcttc aacgtgtcat cctgatactt attactcatg
    14341 tagtcctccc caaagcttct ctattcttcg atagtttaac atatttttcc aagattttct
    14401 gttaatttca gcaaattctt aaggaagtga aactgttccg ttactccaac tggcaggaat
    14461 gactttatga taatcgcccc agttgtcgtg tactttgtaa taacgttctc ctgtttcagt
    14521 ttcaaaataa gcgtacgctg tcacccaatg attgccatat gtactgccaa gtactttcaa
    14581 aataccaatc atcacaggtt tgccttcacg tatacgtttt gtagctcgct gccatgaacc
    14641 tagaagagtt gctcgtgcac gctcatgatt gccattcttc tttaaaaaac tagaaatccc
    14701 tgtactaacc tgaaaaggaa tcgtaggaag tcctagtggt tggatctggc tacgcaatgc
    14761 cttcgtcaaa accaacgaat cagccgtatt tttcttgcga atctcatttg gaagcatcca
    14821 ccccttacga tagtcttgat aataggcaag gagaactgct gccgcgtaag taccacaaag
    14881 atagcctgag ggggtagccc atttcttata cctcaaaaaa cgttcttctg gcaatcccac
    14941 ccagcaattt gtgagttcct ttcctgacct tttttcttcg atcaaaacgg gaatatcttc
    15001 ttttctgttg atccatctag ataactcgat tggctcttca ttgatcagct tccatttttt
    15061 acaagaaaga ccctcttgat aagtatattt tgctggagaa tattctaccg gatgtcctga
    15121 ttgatcgata atcacataac tttgatcttc aaaaaccaga gctaaaaaaa gcaatttact
    15181 ttttcttgac tgcagctgct gagtgctggc taatttttta atttttttat ctactttgaa
    15241 atataaaggt ttatccacta cttgattcag ttgggatcgc ctcctttttt tcattataag
    15301 tgaaggattg aaaaaaacaa atcagtttga ttgttcgaat tttcaatttt ttatgttcta
    15361 tttgttaatt ccttcatttt gtaagataat gggcacacga aacaaaaaag gagcgatcga
    15421 tgaatgaaca aagaacgatt gaaacaagat ttctatgaag cagtcaatga agaatggcaa
    15481 aaaacagcaa aaatccctgc agataaacca gctacaggcg gtttccaaga tttagttgac
    15541 gggatcgacc aacttttgat gggagaaaca gacgatctgc ttgcccatcc agaaaaagtg
    15601 tcttcagaaa aaatgaaaca tttccttgca tattatcaac tggcaaacga ttatgaccga
    15661 agaaatgagt tgcatgctca accacttcaa cctataatcg aaaaagttga atcattgcag
    15721 tctttcgacg aattgaataa gcaatttcca gaatggctgt tggatacatt accattgcca
    15781 tttaatctgg atgtagatgc agatatgaag aatgcgcaaa cgaacgcctt ctttgcttat
    15841 ccgccttctt tattccttcc agataagacg tattatgcat cagaccatcc caacggtgca
    15901 caactaatag gcgttttctt tgatatggct gttcagttat tagagcttgc cggcaaagaa
    15961 aaaagtcagg cagaagcaat cacggaacaa gcagtgcaat ttgataaatt gattgctcct
    16021 catgtaaaaa gtgcagaaga aaacgcagat tacagcaaaa tgtataatcc gcaatctttt
    16081 gatacattta ttcaatacac agataaactg gacttgaaaa aacttgtcac gggtttgatt
    16141 gggacaactc cagataaagt gatcgtaact gatccagtgt acttcgatca tttgaatgac
    16201 atcctgacag aagctcattt tccgttattc aaaagctgga tgatcattaa aacagtacgt
    16261 tctcttagtg gttatctatc agaagaattc cgccaagtca gcggaatcta ttctcgcgta
    16321 ttgtctggaa cagacgaagc aatgcctcag aaaaaagcag cgtattacct tgcctctgga
    16381 caattcgatc aagtagttgg cgattactac ggaaaaaaat attttggcga agctgctaaa
    16441 aaagacgtag aacaaatggt gaaaaaaatg atcgccattt ataaaaaacg tctagaagaa
    16501 aatgactggc ttggggatgc aacaaaagaa aaagccgtca taaaattaaa taacttaggt
    16561 atccaagtag gctaccccga taagatccca gcattattcg accagttcaa aacagtacct
    16621 gcagatcagg gtggtacttt gctttcaaat actcttgttt tcagcaaact cacattaaaa
    16681 gatcgcttca gcaaatggaa caaaccagtg gatcgttcag aatgggaaat gagtgctgac
    16741 acggtcaatg cttattatca tccatttcgg aatgtgatcg tctttccggc agcgatcctt
    16801 caagcaccat tttacagtct agaacaatca agctctgcta attatggtgg aatcggagct
    16861 gttatcgctc atgagatttc ccatgcattt gataataacg gcgctttatt tgacgaatat
    16921 ggcaacttga acaactggtg gacagaagaa gatcttacac aatttcaaaa caaagcacaa
    16981 gcaatgatcg aagaattcga tggtctgcct tttgctgacg gaaaagtaaa cggaaaatta
    17041 accgtttcgg aaaatattgc tgatgcaggc ggtctaagct gtgcattgga agcagcaaaa
    17101 acggaatcag atctttctat cgaggaattc tttgtcaatt gggcaacgat ttggcgtaca
    17161 aaagcaaaaa aagaatacca acaactttta ctgcaaatcg atgtccatgc ccctgctaaa
    17221 ctccgagcaa acgtgcaacc aaaaaacctt gacgaattct atgaaacatt tggtatcacg
    17281 gaacaagacg ctatgtatct agcgccagaa aaaagagtgc gaatctggta agaggttgtg
    17341 ccagaagtgg tcagcttcaa gaaataagaa ggaattgggg aaaattgctt ctcaaatttt
    17401 tgtgacattt cggcttattt tttgaagaag ttacttctgg aataccatgt atcagaggtt
    17461 gtgaaaaagc tgcttagttt caagtagtaa gaaaaatttt gtgaaaatgg ctttccacat
    17521 ttttgcataa atttgactta ctaccgagaa actggctttt gaacaccgtt tatcgagagg
    17581 ttgtgaaatc agcgtcctga cctgagtatt agagaaaaaa acggaaaaat agttcctcat
    17641 attttgccgt ttgttgagct aataccgagg gtcagctgat tgaacaccgt ttagtggaga
    17701 ggttgtgaaa aagctgtcct gcatcaagta ataagaacag ccaatcaaaa gcagcaagga
    17761 gaacctcatc tataaaaaga tagaaggaag tgagacatct attggtctca tttccttcta
    17821 tttttacttt cctcagtcaa ttgttttaca tcataaaagg agaaattcca cttatttttt
    17881 tcgctgtttc atgacataaa caactacatc gattaacaaa attcctccag ctaatgctag
    17941 caacgggtta ttaaattctc ccgtttttgg gagtccttga gtaccatttt tttcactttc
    18001 ttttgctgtc ctatccggat gagaaggttt tccatttggt gattcatttc ctggattttc
    18061 tctttctggt ttgtcatttc ccgggggcac atcggcagtt tctcgcacag tgatcgcttt
    18121 ttgctgggta acagattctg tatgagcaga ccatttttcc ccatcaaata tttccgaacg
    18181 ataagtgact tctagcgtat attctccttt tgaaggtgct gaaaaaatag cggtatgatt
    18241 agaaaattga gcacttgact gtgtttcaac gatttggatc ttttctggga aataacgcat
    18301 atcttcaaag acaggcgttc cttgatttgg tgtgaaagtt gacacaaaaa ctgtaaaagg
    18361 cttcagttca atgatatttc cttctgcatt ctccgccaca ccatttgctt cttgtataat
    18421 aatcggatta ttttgttcat ttggttttgt ctgatttggt tcttgtacga ttgcatactc
    18481 tggatattcc gaagacggcg aggtttctcc gtcaaaaata gcacctacag ataatggaag
    18541 accatccact ctttccttta ctgtttgacg attccccggt ttaatctgca tcagtccatg
    18601 aacatggata cttccatttt catagcgcgt aacaggctgc tgaccttctt tcgaacatgt
    18661 atttagagac tcgatccaat cttttgatac ggtatgtcca agagtatttt ctgattgttt
    18721 ctctcgttca ttccaatagt agttcaacga gtggtagatt tgatcttcgt tttgattcaa
    18781 tgggcggatc tgctctctca tctcaagatt ctctgttcgg aaagataaga taccagaagc
    18841 atggtagtct gtgtttcctg ctgaagaggt ataaagagcc acattatatg aaccgttatt
    18901 aaaacttgta ctgctattga cgataatatc tgttccgcta ttggaatcga ttcctttcgc
    18961 aagattttcg aaagacaaac tattgatcaa ttcatgaggg cccgttaaag aagaaccgcc
    19021 cattttgaat ccattaccgt taccttctcc ctcaattccc ggtacccagc cgtttcgata
    19081 agcaactgag tttttgatga ttacttttcc gatcgaacct gtttcatttt tagcaaaaag
    19141 gtcccaaccg tcatctgcat tatgatacgc gatacaaccg tcaaatacat ttccttctcc
    19201 tattgtcagt ttggccgcaa atccatcggc atcttcaaat cctggatcgg cattttcaaa
    19261 agatgtacag ttcttgacta agttatgcgc tggccatgct tcgaaaggat catttgagct
    19321 accactgatt tggattcctg tatttccatt ccgataagca tggatctctt caatcaaatt
    19381 atggtttcca gaaatctgca atcctttttg catagcggca ctatttgtaa cgtcaaaccc
    19441 acgtaaaacc cagtaatgac taaacagtgt catcccattt ccagttcctt taaaatcaag
    19501 tacaggtcgc ttgttttctg gatttttctc tgcaatcaat tgaatcgggt tttctcttgt
    19561 cccgttaact ccttttggaa tcgtcaatcc tctttcaaag gaataagttc caggagccag
    19621 gacgattgtc tgcccagcat atgcgtatct caatgcttgc gtcagagata acggattttg
    19681 tctgcttccg tttcctgtat ctgacccttc cggtgttaca taaactgtcg aatagttagg
    19741 tttacggtag tcaactgtat gcagaatctc ttttgtttca taactagcca tctctacgta
    19801 ttgttctggc ggatagtttt tatctggtgt aaaactgaaa gtaaattcgt tcgttccttc
    19861 catcagtttt gtctgataat caaattcccg atttgcagtg attgccaagt cttttgcgtt
    19921 ctcaagtacc tctcctgttg cttgattttt gattgttaat aatccgtcag catttgctct
    19981 aaaggacata gtatggtctt ggtttcctga atgattacta gaggtcacag tgtaaatcgg
    20041 atcaatcaag cgaatgggcc tttcttgtcc aggaggatct gtcgcaggat ctgagtaagc
    20101 cacttcgatt ccttctacct tgatcgtcat attccttgct gcagcaaatc ctgcataaat
    20161 aaccgattca tctgaagcgt ataatttttc ccagtcatac atgatgtcag aagccatttc
    20221 ttctcctgtt tcaggatcgt aataatatgc ctctaaacca gtattcgttt ttttcatctc
    20281 tacgtccagt ttagtaatcg agttcgtggc cggaaacaga ttcccatgac cgtttccgaa
    20341 tatattataa gaacctgttt ctttttccaa gaaccctgct gaagtctcta aaggtgttgt
    20401 ttccactgag acactcccag gagctggcgc agcttgcgga tcttcagatg atattcctgt
    20461 gattgcccgt gtccctaatc caagtcgcat cgtatatttg ctgccgctcg tgttgaccac
    20521 ttcttgtcta tccgagtccc agacatattc gatccgactg cctagtatgg caaatgaatt
    20581 tgaataaaat gcctgcccaa acaaatgatt ttttggtact gcgtctctta ccattaaagc
    20641 aaatccttct tgggcattcg tataggtcca agattctatt tcgatcgtcg cccgcatcct
    20701 aaagttgatg tctttgggga ttgcttgata ataataggtc attccatctg atccgcttga
    20761 ctggaatttt ccgccgttat tcgtggaaga gagccgcacg ccgtcttcta atggttcaat
    20821 ggcataccta ctagcacttg tgctttctcc gaaaacaacc cctttccact cttcatttgc
    20881 ttcttcagat tgcttttttg tcttttcatt ttctgattct ttcatcatag gatcatttcc
    20941 ttcttccgta tccatatctt cactagttct tggtacttcc tccattgttg acatcccttc
    21001 aatgttcacg tgtgcatttc cttcgttcac agactgttgt tcgttagcag caacttcaac
    21061 gacagaaatt aaaaccgggg tactgagcat aaggagattc atcattagcg cactgtattt
    21121 tatacgtttt tttaacaagt gtattcctcc cgcaacaaat tagaaagcgt ttacttaaag
    21181 tattacctaa tttattttta ctgtcaataa aaaacaaaat tataataagt gtattttata
    21241 aaaagaaaaa atataactta agttgttgat aataaagaga tttattaacg taaaaagaat
    21301 aagatttttc aaaataacgt ataaaaaaga gcataaaaca aagtcgtttg ttttatgctc
    21361 ttcttttatt attttgtgct ttttatttta tcaaattact ttgttttttt ataaaatttc
    21421 tgcgcctagt gtggattcaa aatgtctcaa tgcccattca tgtccaacgg gatcgaaact
    21481 tgccacggca tctttgaaaa tatggagttt gtatcctaga ttatacgcat cgactgctgt
    21541 atgcaacaca cagatatctg tacatacgcc ggtcaaataa atatctgtga tctggcgttc
    21601 tcgcaaacgg atgtctagat ctgttccact aaaagcggaa taatgccgtt tgtctatcca
    21661 ataaacattt tcctcttgct catagtcttg gtataaactt tttaaagagc cgtacaattc
    21721 ccgtccaccc gttcctatca cattatgcgg aggaaataag cggttctccg gatgaaagga
    21781 atcttttgga tcatgcgcat caatggcaaa aacgacaaaa tccttttgat caataaactt
    21841 ctttgtatga gcagtcagct ttttttcaat tacttgtcct gctgtcccag tagtcagctt
    21901 tccatcctct gcaacaaaat catatgtgta gtcaatcgag atcaatgcgt tcatcttagt
    21961 cctccttata cgagatgttt gacaaattcg atcaccattt ctgctgatcg tttgcctgcg
    22021 tcttcgataa attcgtcaaa gctttgtgtc gccgagtgat ctgctgtgtc gctcattgca
    22081 cgtacgatca aaaatgggat attgaactga cgagctgttt gtccaacagc ggctccttcc
    22141 atttcgcaag ctaatgcttc agggaaattc gttaagattt ctttgatttt atcttgcgag
    22201 tcgacaaatg tatcacctgt aacgatcaat ccttcttttg cgttcaaatt cgttgctttt
    22261 gctgctttaa ccatttcact gcgcaaatat gtgcttgctt cataatatag aggcattcct
    22321 ggtaattgtc ctggtttgta gccaaatcct gttgcatctg catcaaaata agctactttg
    22381 tctgatataa cgatgtcacc tacttgtaag ccttcaccga ttccgccagc tgaacctgta
    22441 ttgatcacca tgttcacgcc gtattgttgg atcaacagac ttgtggtaat agatgctaag
    22501 acttttccta taccggaacg tacgacgatc acttcgtggt tacctaatga acctgaaata
    22561 aataaagcgc ctgcgcgttc ccatgataat ggttcgctta ggttctctct caaaattttt
    22621 acttcttctt ccattgcgcc gataataccg attttcatct ttttaattcc ttctttctat
    22681 ataaatgcga ttgctaaaaa aaccacacat aacattagga taacaataat aagagatttc
    22741 atcaaaaaag agttccattt ggtcgtcttt tcccgttcgc tgatccttgt tttcgtgatt
    22801 ggtttattct ttttgctttc tttacgataa aagctggcaa tctttttttc ttcttgctga
    22861 taagctgttt ctgcttttcg ctgttttttt aatgactcgc ttgcttgtgc ttgttgtcgc
    22921 ttgcgaagtt cgcttcgcgt aataagcggt cctttggcca taagccgatc cctctacttt
    22981 cctttggtca atagttccca gtattgaatc gcataaatcg tctttgcatc acaaatcaac
    23041 tgatctttca tcgcttgttg cgcctcttca agagttagat gatacaactc cagtacttcg
    23101 tcttcatctt gtgctaaagg attctcgacc ttctctaccc cttgtgcatg ataaatatga
    23161 aggacttcat ttgcaaaacc tggtgaaaga tacatcgaag taagatggct cagcgacttc
    23221 gcacgatagc cagtttcttc ttctaattct ctagctgctg tcatttcggg attttgtcct
    23281 tctcctggat cgatttttcc agctggaatc tccaaaatca ctttttctaa aggttttcga
    23341 aattgtttga caagaagcag acgatcttgt tcgtcaaaag caatgatccc aacaccgcca
    23401 ggatgaaata ccagttctct cttcgaagtt cctccatctg gcaaacgaac ttcgtctaca
    23461 gcaacatcaa taatttttcc gctatagatt tctttgcgac tgattgtttt ttcttcaaat
    23521 tgctcattgt tcagcatatc ttctcctgct ttctttgtaa tcataactgc tttttttcat
    23581 ttttcaattt ttctcaaaaa ctccttatta gtttaccata gataaacctt agattttctc
    23641 taaatataga aaatccttct ttagtccgat actctttcta gtagtccgta tgctaaaata
    23701 agtatgtaat cgaataacga aaagaattca atactcaacg ataaatgaca tggagggttt
    23761 attatgataa aacgaaattg gccgtggctt ctagcattgg tcttgctatt tctctttggt
    23821 ttttcttttg ttctaggact tttattgata ggtgtagttt tagttttgtg gggacttttt
    23881 ggttcgcgca ggaaaaaggg aaaacaagaa gaaattcctg cactgactaa cgaacttgaa
    23941 actcactatg aaaaaagcgg tatgacagcg aatgaaattt cattttttcg acaaacaatg
    24001 aatcaaacaa aaaatgagat caatcaattg caaatgaata tgcagcagac agccaaactt
    24061 aaagcaatcg atctccgcca tgatccagtc aaagcagcaa aagctttatt caaagaattg
    24121 gtgaaagaac caaaccgact gcatgaagca agtcagtttc tttatacgca tctgccgaat
    24181 ctagttgatt tgacaaataa gtataatgag atcaatgacc atgagatcaa aaacaaacag
    24241 acctatgaaa aactagaaga aagcgcgcag atcatcgacc agctgtcagc tttaatcgca
    24301 caagattatc aaaaattcgt tgctgaggat ctagatgata tcgacgtaga gatatctgtt
    24361 gcgaaacaga gcttaaagcg tgataataaa tatgaaccag aacaaaagga ttaactcttt
    24421 tgttcataaa agaagactcg gaacattcag atgatgtctg gctgtttcga gtactttttc
    24481 taaagtagag acattcatgt aagaatcgag aacagattca acaaggagga attttttatg
    24541 gatcataaac cgactgaaac aaaagatgtt acaccagtta acgatacact tgaagattta
    24601 ttgaacaacc cgttttcaac tccaacagat acgctgacca cttcacaaca agcggagatt
    24661 gatcagctcc aagagcaaca gacagctgct cgtttaattg acaaactacc ggcggaacgc
    24721 caagaacaag ctaaacagct agcagcaaaa atcgatgcta atgatgcaca gtctgtcatc
    24781 agctacggat cggctgccca agcaaaatta agtgaattct cacaatcgat gttgaatcat
    24841 gtgcaagcac aagatattgg tcctgtagga gattccttaa ctgaactgat gtatcgtctc
    24901 caagaagcca atcctgacga actgcgtgcc ggagaaggga acatcttcca gcgtgtcttc
    24961 gggaaggtca aacaatcgat ctatgaagtg acagcaaaat atcaaaagat tggtgcacaa
    25021 attgacaaga tttcagtgaa attagataaa gaaaaagacg gtctgctaaa agataatctg
    25081 atgttagaac agctttacca gaaaaacaaa gactactttg atgcactgaa tatttatatc
    25141 gctgctggag aattgaaaat ggaagaactt caaacaacga tcattccaga agcgatgaaa
    25201 agagcagaag aaactggcga tcagatggat gttcagattg ccaatgatta cacgcaattc
    25261 ctagatcgtc tggataaacg tacgcatgat cttcgcttag ctagacagat cacgatccag
    25321 caagcaccac aaatccgttt gatccaaaac acaaatcagg ccttggctga aaagatccaa
    25381 gcatctatcg ctacagccat tccgctgtgg aaaaaccaag tcgtgatcgc attgaccttg
    25441 cttcgtcaaa aagatgcagt aactgctcaa cgccaagtct ctgaaacaac aaacgactta
    25501 ttgaagaaaa attcagaaat gctgaaaatc tcagccatcg aaacagcgaa agaaaatgaa
    25561 cgtggaatcg tggatatcga gacccttcaa actactcaaa atgatttgat cgaaacaatc
    25621 caagagacat tgcgtatcca aaaagaagga aaagaaaaac gtcgtcatgc agaagtagag
    25681 cttggacaca tggaagaaga tctgaaacaa aaactgttgg atttaaccca atagatcacc
    25741 tttcgcttgt tactaaaaca aacgcccaac aacagtttat tacaactgtt gatgggcgtt
    25801 tttcttatct ttcttctaac ttctccattg gagtctattt ctcattcatc ttgctgtgtc
    25861 catagccata gccaaaataa atgatcagtc caataaccat tacgataccg aacacgatcc
    25921 atgtcacagt ttgcagacga agcatcaata caatacaagt caagatggaa atgattggca
    25981 atagcggaac gaatggcact ttgaattctc cagcttttgg tttgccaaac atttttctca
    26041 acttcagtaa gcctagacta acaagcatca aataggcgag cgccatgata ttcgttagtt
    26101 ccgctaatac attcaatggg aaaaatccgg caaagaatac agctgccaca ccagcggcat
    26161 aagtcgcttt tttcggtgta cgatgctttt gatcgatttc tgtcataaac ttaggaagta
    26221 agccatcctt gctgacagca aacagtaaac gagcaagtga atacatcatc gagattgtta
    26281 ccgtcagtag cgttaaaatg gcccctacag cgatcaccgc gcccactgtc ccatgtccta
    26341 catacctcat tgcaaaagcc actgggtcat tgactcctag ttcagtatac ggaacgattc
    26401 ctgtcaagat cagcgtcacg atgatgtaaa ggacagtagc aatcagtatc gaaccaatga
    26461 ttcctcttgg cacatctttt tgcgggtttt tgacttcctc ggctgccatt gcaacggcat
    26521 caaatcccaa gaaagcaaaa aacacaagag ctgcaccatc tagcacaccg gaaaaaccaa
    26581 aaggcatgaa tggctgccaa ttatcaggtt taacgaaaaa tattcctaca atgataaaca
    26641 acgcgatgat accaaatttg acatatacca tggcattatt caaacgtaat gctttcttgg
    26701 cttcaagcga cacgatgtaa gtgacgaata tcactacgag caccgcaatc aagtcaatgt
    26761 atgtaccatt ttccggattg tacccgccag ttaatgcttg tggaagttcg gcccctaaac
    26821 ttttcaaaaa accttgcata tagccagacc atccggaagc aacagaggaa accgctagta
    26881 aaaattcccc gatcaacaac caccctgtca gccaggcagc aaattcacca aatacaacat
    26941 acagataggc atatggccca ccaatcactg gcactcgcga agcaaattct gcgaaactta
    27001 gtccagacaa aatgacaacg attgcagcta agacaaatga aaatgacagt gctggaccag
    27061 cattttgatt ggccgcaacc cctgtcacca caaatattcc cgtaccgatg atcgcaccaa
    27121 ttccaagcat gatcaaatca gacgttttta gttctttttt catctcactc gtatgattga
    27181 gattgatctc tttcttacga aacaaatcca ttgaagttcc tccccatttt aggttggaaa
    27241 acagcgatta aactgttttc atatacccta aaaggatacc acctaaaatg actaaaaggc
    27301 aaccaacaat aacataaatg agctcttttt tcgtttttct ttcgccaagg atgaaaatcc
    27361 cacctaaagt agagataatg atccccattt gtgaaagtga gaagccaaca gctaaaccaa
    27421 gtgatttgac tgttagaagc atgcagatgt ttcctaagcc ccataataat ccacagatca
    27481 tgtttttcca cacaaactga tcgactttaa ctttacggaa agcaaagaag cttgcgccta
    27541 agatcattcc gatactttga ggtaagataa ttgacatcgc atccaaattc gcccagttga
    27601 cgatgatggt atatacacca taaccaatcg tagagaagat caatgctcta aaacccttac
    27661 caaaatcaag cattttatta tctgtatcta tttttccttc gtcatcttgt cgggcagtca
    27721 aatacgcacc gcttacaaga agagctaaag caataatacc gtatacataa tctttcgttt
    27781 gtgtccattc atggaagaaa acggctcccg caatcgtatt caaaattaat tgaaaaccag
    27841 tagacaatgg taaccctaca gaaacaccca tgtacttcat tccatggaac tgtccatttt
    27901 gtccaacact ccaagctaag ccggataaaa atccgatcaa gaaaatccaa ggggtgatta
    27961 caggactaac aacgaaaaag acaactaaag aaaacagaaa tgcaccgatc gtcattccta
    28021 gtgtttgttg attggcatcg ccaccaattt taccacttac taaaccaata ctaccccatg
    28081 ccaacatagg gactaatgct attaaaattt ccataaccaa tctcctttta tttcacatga
    28141 taagaaactt atcagcgaaa acgttaacaa cacaagcact ttttttcgtt tctaacgatt
    28201 ttctaacgtt tttcattata aaaatttaag attgggaaaa ataaagtcat tgttgtccct
    28261 tttccttcag ttgattcagc cgtcaaatgg atacctaatt tttcggccag attttttgct
    28321 aaataaagtc ctaatcctgt tgaatgtgtt ttgctaagtc gaccatttct cccagtaaat
    28381 cccttatcaa agatccgttt caagtcttcc gctgggatac cgatccctga atctttaact
    28441 gaaaggctga ctccttgtgc ttccttttct atgctcacaa tgatgtttcc gtgatccggc
    28501 gtatatttga tggcattact aagcaattgg ttgaagataa aagcgatcca tttagcatcg
    28561 gtcaaaacag tatgatcctc accaacaatc tcgtagcgaa tatttttttg gataaaataa
    28621 tttgcctgac tgcgtatcac aggctgaatg attcctttta gcctatattc ttggatgagg
    28681 tagtcccgcg aaaaactgtc tagtcttgca taatacaaaa cttgttctac gtattcatcg
    28741 atttttgata attcattttc tagtaatgta tacttttgat cgtcaatatc gaactcgatc
    28801 gaacgaacta gcaatttaga agcggaaagt ggcactttga tttcatggac ccatgagtca
    28861 atataatctt tttggtcttg ttgattactg attgctgatt gcattacttc ttggtgttca
    28921 cggatcagct gattgatata ttcttctacc agtttttctt cttctgttcg tccaccgctc
    28981 aaatagtttt gcaaagggga agttttttgt atgtcggcta attttcccca ccatcttctc
    29041 ttgctcaagt aaccacccag cagataaaaa atcagaaaga cgccctcaat caaagctaaa
    29101 taagcaattg tgctcaaatc aactttgatg tttggcgcca gccacatcac aaagatcgtc
    29161 aatgcaataa aaaacagcca tcccaagatc aatgtccact gatctttcaa atatttaaaa
    29221 aaattcatct taaccgctca tcctttcagg gaacgatata tccctgtcct acttttgttt
    29281 cgatatatcc ttggatacct gcctgttcga tttttcggcg taaccgattg atgttgactg
    29341 tcaatgtatt gtcatctaca aatcgttcgt catcccacag tgctcgcagc aatttttccc
    29401 gacttaagat ctttccattg tgcttcatca aaataaataa tagacgatat tcatttttgc
    29461 tcaaatcaat gatctctccg ttgatttcca tacttccgtt gtcaacattc aacgtaatgc
    29521 cattgtggct catcatttca ctagataatt ctgtgtagtt gtaagaacgg cgaagtaatg
    29581 cattgatttt tgcaatcagt acatcgattt ggaaaggttt tgtcacaaaa tcatctgccc
    29641 ccatgttcat agccatgatc atatccatat tcgtattcct gctggagata aaaatgatcg
    29701 gtactttcga tacttcacgt attttttgac accaataata gccatccaaa acgggaagat
    29761 taatatctag taatacaagc tgtggttctt ctctttcaaa gtctgagaac acttgattga
    29821 aatcggtcgt tccaaaggtt tcaaattgcc atttctcaag ttcctccatg atcaattgtc
    29881 gaatgatctc ttcgtcttcg actaccatga tttttgccat aaaaaatccc tccatctttc
    29941 ttcttgctac tacaatatca aagaagccct tgtgaaacaa gttggcttac ctggaaaatg
    30001 tcattttagc aaacgttaaa aaaaactgga aatatgcgat ttaatcgctt ttgtcttttc
    30061 aatacagctt aaatttatta tgttattctt aacaattggt ctatgatctg ttatttttcc
    30121 ttagttgttt ttgtctttta aatttccaat aacaccaata accgaaaagc gttagcacta
    30181 gcaatatacc tagaaggagt ataagtaatc gataaagatg gtattttttt gtctgttcta
    30241 tctttgaaga gacttcttct gtaaagggaa ctcgccttcc tgtcactagt aatcggtgag
    30301 tgttcacggt gtaaggtgta caagtgataa gtgtgactag atcctgcttt tctctgattg
    30361 ctaatgtatt tgtttttgtt ggaaggacaa caattttctc aacgacttca taagcgagca
    30421 tccgaccata cacttcaaga tagaatcggt catcttgctc catttcttca agatccgtaa
    30481 agagtttttt ctcagcaata ccgctatggg cggtaatcac ggaatgtgta ctctctcctc
    30541 cagttggaaa agaggtgcct tgcaggactg tcgctcctct atctaacaaa agatcattcg
    30601 tttcatcaaa taaaggcaag ctaacattga ttttcggaat atagattgct ccgatcatat
    30661 gttgttcgta gtattctttt cctggatttc ggacatttct aaccgcttgc tcaaaaggat
    30721 ctttgacttg tcccattcct gggattactg atgtatgagc aagcgtctga tttttctttt
    30781 catgcactgc taattgttgc tcatgttttt cttctttatc gcgttcaagc tgcttttgat
    30841 aattctcgat ccttctttga tccaaataat tgctgagagc atctgctaaa aatggatatg
    30901 taaaaactgc agctccggca agaaacatca ctgccataaa taattgtaat aaaagactga
    30961 tttgggtttg aggtctatta cctgttctct ttttcatttt cttcaccttc ttatttaaaa
    31021 aaactgcagc aatcggtttt ataaaggttg ctgcagctta tttttgttgc ttatacttca
    31081 gacttcattt taaatttacg gtaccagctg tacgctccaa tcatcaaact tattccgatt
    31141 agtaagaatg ccaagagccc gttcccacca gtagcaggaa gtgacccgcg tttcatattc
    31201 ggtactcttt ctggccctgg attttctact cctacgatct gaatttcttc attatagctt
    31261 ccataagaga tgataaattc agtaaaggct gcctcacctg ttggaagtac ataa
//
LOCUS       DAPBCF010000028        30977 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.028, whole genome shotgun sequence.
ACCESSION   DAPBCF010000028 DAPBCF010000000
VERSION     DAPBCF010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30977
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.028"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..171
                     /locus_tag="RD508_001615"
     CDS             <1..171
                     /locus_tag="RD508_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDT7736219.1"
                     /translation="SLFPLYHGSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFK
                     IEYTKKRQRLAY"
     gene            406..642
                     /locus_tag="RD508_001616"
     CDS             406..642
                     /locus_tag="RD508_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736220.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            649..2601
                     /locus_tag="RD508_001617"
     CDS             649..2601
                     /locus_tag="RD508_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HDT7736221.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="RD508_001618"
     CDS             complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="RD508_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HDT7736222.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3532..4572
                     /locus_tag="RD508_001619"
     CDS             3532..4572
                     /locus_tag="RD508_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDT7736223.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            4670..4858
                     /locus_tag="RD508_001620"
     CDS             4670..4858
                     /locus_tag="RD508_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HDT7736224.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(4916..5269)
                     /locus_tag="RD508_001621"
     CDS             complement(4916..5269)
                     /locus_tag="RD508_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7736225.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            5800..6222
                     /locus_tag="RD508_001622"
     CDS             5800..6222
                     /locus_tag="RD508_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7736226.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            6219..6449
                     /locus_tag="RD508_001623"
     CDS             6219..6449
                     /locus_tag="RD508_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7736227.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            6947..7147
                     /locus_tag="RD508_001624"
     CDS             6947..7147
                     /locus_tag="RD508_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HDT7736228.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            7174..8367
                     /locus_tag="RD508_001625"
     CDS             7174..8367
                     /locus_tag="RD508_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7736229.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(8435..10000)
                     /gene="guaA"
                     /locus_tag="RD508_001626"
     CDS             complement(8435..10000)
                     /gene="guaA"
                     /locus_tag="RD508_001626"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDT7736230.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(10059..10982)
                     /locus_tag="RD508_001627"
     CDS             complement(10059..10982)
                     /locus_tag="RD508_001627"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HDT7736231.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            11178..11783
                     /locus_tag="RD508_001628"
     CDS             11178..11783
                     /locus_tag="RD508_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7736232.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12091..13107
                     /locus_tag="RD508_001629"
     CDS             12091..13107
                     /locus_tag="RD508_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDT7736233.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13248..14549
                     /locus_tag="RD508_001630"
     CDS             13248..14549
                     /locus_tag="RD508_001630"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDT7736234.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14595..15257
                     /gene="deoC"
                     /locus_tag="RD508_001631"
     CDS             14595..15257
                     /gene="deoC"
                     /locus_tag="RD508_001631"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDT7736235.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            15278..15676
                     /locus_tag="RD508_001632"
     CDS             15278..15676
                     /locus_tag="RD508_001632"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDT7736236.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15742..16824
                     /locus_tag="RD508_001633"
     CDS             15742..16824
                     /locus_tag="RD508_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7736237.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            17036..18598
                     /locus_tag="RD508_001634"
     CDS             17036..18598
                     /locus_tag="RD508_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7736238.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18591..19724
                     /locus_tag="RD508_001635"
     CDS             18591..19724
                     /locus_tag="RD508_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7736239.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19724..20680
                     /locus_tag="RD508_001636"
     CDS             19724..20680
                     /locus_tag="RD508_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7736240.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            20779..21945
                     /gene="deoB"
                     /locus_tag="RD508_001637"
     CDS             20779..21945
                     /gene="deoB"
                     /locus_tag="RD508_001637"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDT7736241.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            21969..22787
                     /locus_tag="RD508_001638"
     CDS             21969..22787
                     /locus_tag="RD508_001638"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDT7736242.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            22804..23511
                     /gene="deoD"
                     /locus_tag="RD508_001639"
     CDS             22804..23511
                     /gene="deoD"
                     /locus_tag="RD508_001639"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDT7736243.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(23809..24495)
                     /gene="gpmA"
                     /locus_tag="RD508_001640"
     CDS             complement(23809..24495)
                     /gene="gpmA"
                     /locus_tag="RD508_001640"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDT7736244.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(24667..25248)
                     /locus_tag="RD508_001641"
     CDS             complement(24667..25248)
                     /locus_tag="RD508_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7736245.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(25381..26064)
                     /gene="rpiA"
                     /locus_tag="RD508_001642"
     CDS             complement(25381..26064)
                     /gene="rpiA"
                     /locus_tag="RD508_001642"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HDT7736246.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            26383..26796
                     /gene="rpsL"
                     /locus_tag="RD508_001643"
     CDS             26383..26796
                     /gene="rpsL"
                     /locus_tag="RD508_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDT7736247.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            26880..27350
                     /gene="rpsG"
                     /locus_tag="RD508_001644"
     CDS             26880..27350
                     /gene="rpsG"
                     /locus_tag="RD508_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDT7736248.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            27444..29531
                     /gene="fusA"
                     /locus_tag="RD508_001645"
     CDS             27444..29531
                     /gene="fusA"
                     /locus_tag="RD508_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDT7736249.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            29703..30890
                     /gene="tuf"
                     /locus_tag="RD508_001646"
     CDS             29703..30890
                     /gene="tuf"
                     /locus_tag="RD508_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDT7736250.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
BASE COUNT         9895 a         5625 c         6425 g         9032 t
ORIGIN      
        1 tctctgttcc ctctttatca tggaagtgca aaaagtaata tagggattga taaccttata
       61 gaagttatta ctaataaatt ttattcatca acacatcgag gtccgtctga actttgcgga
      121 aatgttttca aaattgaata tacaaaaaaa agacaacgtc ttgcatatta agtagttcag
      181 ttttggagta caaaaagtga aaatgtaaac ctaaatgagt atcaaattgc aactgaattt
      241 gatactcgtt ttttattgtt aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag
      301 ttaaaatgta tataaaaatg cgaacgtgaa ataattattg taggaatgca aattggtgtg
      361 ttaaaatggt tacaatttac taagcaaaaa ggggtgcatt ttcctatgca atttcttgag
      421 ccaaaaaata agaacgctaa gtctgtggat tgggaaatat cagagcaagt aagggtgata
      481 gttaagcaat acgctgaata tgcagagcgt actgaaagcg aagcagtgga tgaattctta
      541 ttgaacattt tagacgataa gaagtttatt gaatggattg ccaacaagcg aagtaataag
      601 cggattgttg aaaaaatggg tatcaaagat agagtgggtt gatagacaat gaccaagctt
      661 aaaagattag ccacgaagga agatgaaatt gtagatgtta aaattccgat ttcaaacgaa
      721 gaattaaaag atagggctaa acaatatgat ttattaactc caaaacgatt tgcaacaagg
      781 tataacaaaa tgttgttctt gccaacgtct tttaaatgga acggttctga atatcccatt
      841 caatataatt actgcatcaa tccgttttgt tgtaattttg ggaaagaaca gcacaaattc
      901 aaagatgtaa aagggaaacc aagtcgatat aaaatgactg gtagttccaa agataaaggt
      961 cataaaggta tgtactgcaa tgacaatcct attggcagag gtgtatcgca aaactgtaca
     1021 gtaacccctt tatctaattg gtctgttgtt gaagaaatta aacgccttat agaaatcaat
     1081 agcatccaag atgttgagcc agattatcaa tttcataaag aaggctgctc ggaagaagaa
     1141 tcaaccccat tcaatgagcc gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct
     1201 caacgctatc aatgtaaggc gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa
     1261 accactactt atcaccaaca aaagaacacc attcttccaa tgttcgctaa gatggttgtt
     1321 ggaagggttt cagtcagtcg tacttgtgat attttaggaa ttggagttgg aacctactat
     1381 cataagctgg agtggctgta taggcgttgt ttggagtttt tagaacgata tgagacacaa
     1441 ccccttcaaa caaagaaatt taacgagatg tggcttaata cggacaagat gcactactac
     1501 ctaaataacg tccgtaagaa aggacaaggt tcaaagaaat atacggggtt tgaagacctt
     1561 aatatgcaaa cgtatatagt tgtatctgct gaggtcttat caagatatgt gttccgttct
     1621 gatgttgcct atgattggaa tatttcaatg gatgaattaa atgaagatac aagaaaattc
     1681 aaagaagacc atctcaatac ttttagtcgt aaaaatgata ggttagattg gtcttattat
     1741 ccacaagaac catccgctaa cgatagcgaa aataggaatg cttatcttca cgaattaggg
     1801 aaaattacta ataggagtag atttgtcgat ggtttaaatg ttgatgctcc ttatactaca
     1861 actgctcact attggttaat taaacaaatg gttaatgccg acgaatggcg aatgattagt
     1921 gatgatgact tctctattag aaacgccttt tatagagtat tcacgaaaga attaaggttg
     1981 agcgatgcac atcattttat ttgccaagtt aacaagacga aaagcagaaa acaatgctta
     2041 aaagaattcg gacaagcaaa agcagaactg ctcgattggg gagatatcag aggattcaaa
     2101 acaaagtttc tacggacttt ggcatctcat tatctaactg aattactaac aagtcatcaa
     2161 ttccacgaag aggctattag taaagatgga gaaagatatc gcaaatatgc cgataaccct
     2221 atcaaacatc cattagccac taaggataaa ggattttatt cagttgattg tagaacggat
     2281 ttatctgctc tggaaccaaa cgaaatcgca aagatgctat taaatgttaa tgaccattcg
     2341 accaatagct ttattcaaca gataagacgt tatatatcat ctcttgaaag accattaaca
     2401 acagctcgtg gtgataagaa gagctatatt tacgctaact tcaatccgaa gtatgctcaa
     2461 tttgcgatta caattctaag aacttactac aacttttgtc gcccttttaa atcagcggat
     2521 aaaaaggttt tgacacctgc tcaaagatta gggattacag ataaacaatt tgattggaaa
     2581 gatataattt atttcaaatg acaaaaagag cttggagtaa tcccaagctc ttgtgcttta
     2641 tctttactgt tcttcttcaa ttaacgcacc cgttaactca ataagttttt tctttcatat
     2701 acatgaaaat agtagttata cggattttta tcattcttta tccctttttg ggcaaatacc
     2761 tcattccatt cctcataatt cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt
     2821 atttttgtga tgtacatttt ctcaacataa gggaaaaaca aattataaat ctgttctcct
     2881 ccgaaaataa aaatttcttc ttcgttttta cataactcaa aaacatcttc tattgaatga
     2941 acaatttcac aaccattaaa ggtaaacccc ttatctctcg tcagaataat atttcttctg
     3001 tcaggtaagg ctcttccgat tgattcaagg ttcttcctac ctaatattat cggatgtccc
     3061 tttgtagtat ttttaacata ttcccagtcc ttgggaatcc tccaaggaat gtcattctct
     3121 ttgccaatca ctctattctt atccatcgca gcaatcaaag aaactttcat ttataacaca
     3181 gcctttttaa ctaatttacc atctaatttc ttatttctat caaaaaacct tttctcatta
     3241 tcctgcccgt tagttgaata agcaattttt tctataagtt atattatcat aataccacaa
     3301 aatcacaaat tttcattcaa ttatcatttt caattgcatt ttataaatca ttttgtatgt
     3361 aatttggtat gtaagttaaa atgaaaaaag tagtccattt tgaagtacat tttgtcattt
     3421 tgtactccaa aactgaacta cttacttgca tatatacgcc tttatagtgg agtactacat
     3481 ttacgagatt cggttagagt atcagaaaaa gaaaaaataa aagttacaga aatgtatact
     3541 tcaataaatg gtgaattatg taagattgat agagcttatt ctggagaaat tgttattttg
     3601 caaaatgagt ttttgaagtt aaatagtgtt cttggagata caaaactatt gccacagaga
     3661 aaaaagattg aaaatccgca ccctctacta caaacaactg ttgaaccgag taaacctgaa
     3721 cagagagaaa tgttgcttga tgcccttttg gaaatctcag atagtgatcc gcttctacga
     3781 tattacgtgg attctacgac acatgaaatt atactttctt tcttagggaa agtacaaatg
     3841 gaagtgatta gtgcactgtt gcaagaaaag tatcatgtgg agatagaact aaaagagcct
     3901 acagtcattt atatggagag accgttaaaa aatgcagaat ataccattca catcgaagtg
     3961 ccgccaaatc ctttctgggc ttccattggt ttatctgtat caccgcttcc gttgggaagt
     4021 ggaatgcagt atgagagctc ggtttctctt ggatacttaa atcaatcatt tcaaaatgca
     4081 gttatggaag ggatacgcta tggttgcgaa caaggattat atggttggaa tgtgacggat
     4141 tgtaaaatct gttttaagta cggtttatac tatagccctg ttagtactcc agcagatttt
     4201 cggatgctta ctcctattgt actggagcaa gcctttagaa aagctggaac agaattgtta
     4261 gagccatatc ttagttttaa agtttatgca ccacaggaat atctttcacg ggcatataac
     4321 gatgctccca aatattgtgc aaatatcgta aatactcaac tgaaaaataa tgaggtcatt
     4381 attattggag aaattcctgc tcgatgtatt caagattatc gcaatgattt aacttttttt
     4441 acaaatgggc ttagtgtttg tttagcagag ctaaaaggat atcaggttac cactggcgaa
     4501 cctgtttgcc agacccgtcg tctaaatagt cggatagata aagtaagata tatgttcaat
     4561 aaaataactt agtgcgtttt atgttgttat ataaatatgg tttcttatta aataagatga
     4621 aatattcttt aatatagatt tgaattaaag tggaaaggag gagattgtta ttataaacta
     4681 caagtggata ttgtgtccta tttgtggaaa taaaacaaga ctacgaatac gagtggatac
     4741 tatacttaaa aatttccctt tatactgccc caaatgtaag aacgaaactt taattaatgt
     4801 tcaaaaaatg aatataataa caatcaaaga gccagacgcc aagacgcaga gccgataatt
     4861 tgagaaatga aactctcatc ttatcggctc tttttgttta tctgaatttt actgactagc
     4921 cttcaatatt tcttgcttca ttgatacctt ttgctagtgc ttccattaag gatagttctt
     4981 tgtctgtaaa gctatccatg tatttttcta cctgtaacct tcgagtgctt ttaatcaaat
     5041 tatctgtagg taagaaaaat tcatcaatag atacatggag taatgataca agatcataca
     5101 gcacttgtgt acttgggtgt tgtcctttgt tttctatatt tgttaaataa cgtgggtcaa
     5161 tttcaatcat tgttcccact tgttcacgag tgagaccccg tttcattcga gcctctttaa
     5221 tcgctaaacc aacggctcta aaatcgtatt tatcttcttt tttacgcata ctaaatcacc
     5281 tctatacatt ttactgttcc tatataacca taaacaggta tagaaaaaca tgttatatag
     5341 tttatgagtt cctatagaac actgtggaat ttattaatgc gatgaatcca atttcaaata
     5401 gaaaggtcgc tgattttatt tacctataca actttataaa atttagtcat actcctagaa
     5461 agtagataaa attggcgact taatggaggg aaaagtcgcc atgagaaaga taatctgtca
     5521 tctagttctc ttaattaagt tcttatcaaa aaaacttatc cacctgtact ggatagatat
     5581 gaccatcaat gtggttttgc agattacata gatagaaaaa tcaaagcata tgaacagaga
     5641 aaacaatctg tttatgtgct tttttggtca cttaataaat atcttttagg atttctcttc
     5701 atttatgcaa caaatccccc gttcgtgtcg gggtttagta tgaagggaga taaagaagca
     5761 catgccactc cctttcacga cagaaagggg gtgaaaagca tgaaaccatc ttcttttcaa
     5821 gaaaccatag aaaatcagtt tgactatatc tgcaaacaag ttattgaaga tgaacgaaaa
     5881 gattacttca aacatctaga cagactatca gcaaaagaag tctcgttttc tgatatagat
     5941 aactaccttg tcaactcttt ttctactgtt gatacgtacg tcactgattt ccaactattt
     6001 aaattatttg gattaagaat caatgttgaa agtgatttat taagtgaagc cctgcgtcat
     6061 ctttcagaga aaaaacggaa cattatttta cttcattact ttatggatat gagtgatgtg
     6121 gagattgcgg agttactaaa tttgaatcgt tcgactgttt atcgtcatcg aataagtgga
     6181 ctagccatga ttaaagaatt catgaaggag tgtaaagaat gaaaacagct tatccaaggg
     6241 ttcccttccc cctcattgta aaggcgacag atggcgacgt ggaagcaatt aatcagattg
     6301 ttaaacatta tcgagggtat acctcaaaac gttcattacg tcgcatgaca gacgaatatg
     6361 gaaattctca tatggttatt gatgaaaccc tacgtggcag aatggaaacg aaactcatct
     6421 ctaagatttt atcgttcgaa attaaatagt cccatttttt cgtggaagcg tgtcgaatcg
     6481 tatccacgct tcccgatttg ggaggtttgt tattccatca aagcatattg tgtgttcagt
     6541 aggttttgat aggctaacaa gccaaacgtt ctttgacaac caaataaagg caatcgaata
     6601 cgtttcggta agaaaagagc tgatgaacta acacgccatg acctacaaaa ttagtgagcg
     6661 attcatgtta gtaattcgaa agtaatcttt agcaggattg ctgccatgac tttcttatcg
     6721 tgataatgat actcccgtat agccatagtc cgagcgttag aagcgtcaca ggcaatgggt
     6781 acggctacat gagaaccatg cagaagtgaa attcctgtga gctttgctag agctgttcga
     6841 ttgctaagat attcttctct tgtcagtgta ttattataaa actatttgat ataattatag
     6901 gtgaatattg gagttttcct agcctataat tgggaaagga gtaataatga taacggtcac
     6961 aaaaaaggat ttagttgagc taggatatgg aacttctttt tcagcagaca tcataaaaaa
     7021 agcaaaagaa ttgatgatta caaaagggca tatctactat caatctcgaa agctagatag
     7081 agtccctcgt gaagctgttg aagaaattct aggaattcgg ttttcaaatg aaaacaggtc
     7141 tgagtagttt ttgcacagta aggagtaaaa actatggtta aagacccaat aaaaaaagca
     7201 aagaatggaa cctattattt tcgtgcaaat ctaggttatg attctaaagg gaaaaaaatt
     7261 caaaaatatc gtagtggatt cactactaaa aaagaagcaa gagaagaata ttcgaaactg
     7321 ctattgatga aaccagaaga attaagtgag aataaggata aaatgacgtt taaacattat
     7381 atctttgaaa ttttccttcc atggtataag acacaggtaa agctcagaac atatgaaaat
     7441 cgcttaccaa ctattaagaa gcatttctct tattttgata aaatggctgt ttccgatatt
     7501 gagcctattg atgtgcaaaa ttggcaacta aaattatcaa agaagtgtaa gtcttcttat
     7561 gtaagagctg ttcaaggact attttcagtt gctatggatc gagcaattgt ccttgggata
     7621 accaccacaa atccatctaa gattattggc aatgtgaaaa agcaaaagtc taaaattgaa
     7681 ttttggacaa aagaagaatt tgaaaaagta atctctctaa tttacaaaga agattactat
     7741 caacactttt tatttatctc tctgtggttt ttatttatga ctggaatgcg aattggtgaa
     7801 gctactgcca ttcaatggga agatattgat tttgactcag gagtactaac catcaacaaa
     7861 acactctatt acaagaatca atcgaattat agatttgttg aaccaaaaac aaaggcgagc
     7921 gttcgtcata ttgtattaga taaatgcaca ttaacttatt tatccgaatg gaaggaagta
     7981 caacaaaatc taattcagac agactttgta atgagctata acggtattcc tacccaaaaa
     8041 catacactat catatgctat tgaacgctat gctaagctgg ctggtatcca tcgaatcaga
     8101 atccatgggt tacggcattc tcatgcttcc ttgttaatca gtatgggaga aaatccactt
     8161 atcattaaag atcgtctagg acacgaagat attgagacga ctttaggaac gtatggacat
     8221 ctttatccta acagtaattt cgaggtagct aacaaattaa atggagccat ttcctttaaa
     8281 gaagcaaaac aaaattatga tacttcacca aagaatcaat ttactgtaga ctacttgcga
     8341 aacaaagaaa tgaaaaaagt gcaataaaag tgcagtaaaa agataagaag agccagaaac
     8401 ccttggtata agaggatttc tagctctcct acaactattc ccactccact gttgctggtg
     8461 gtttagaagt gatgtcatac acgatacggt tgacgtgggc tacttcgttt acgatacgta
     8521 cagagatttt ttgcaagact tcccatggga tacgggcaaa gtcagcggtc attccgtcga
     8581 ttgaagttac agcacggata ccgactgtgt agtcgtaagt acgtccgtca cccataacac
     8641 cgacagagcg gatccctgga agaacagtga aatattgcca gatatcacgg tcaagtccag
     8701 cagctgcgat ttcttcacgc aagatagcat cagattcgcg tacgatttct agcttgtctt
     8761 cagtgatttc gccaagaaca cgaataccaa gaccaggacc agggaatggc tgacgccaaa
     8821 cgattgaatc aggcatgcct aactgagtcc ctaattcacg gacttcgtct ttgaataatg
     8881 tgtttaatgg ttcgatcaat tcaaattgca tatcttctgg cagtccacct acattatggt
     8941 gagatttgat cgtctgtgct gtttctgtac cagattcgat aacgtcagta tacaacgttc
     9001 cttgtgctag gaaagagacg ccttcttcac cagcaagttt tgttgcttcg tcatcaaaaa
     9061 catatacgaa ttcattccca atgattttac gtttttgttc tgggtcagat acacctttca
     9121 acttgtctaa gaagcgatct cttgcatcga ctttgatgat gttcaagccg aattttccgc
     9181 ctagactttc cattacttgt tccgcttcgc ctttgcgtag cagaccgtgg tcaacaaaga
     9241 tagatgtcaa ttggtcaccg atcgcttttt gtaaaagaac cccaacgaca ctagaatcaa
     9301 cgccacctga aagaccaagc aagacttttt tgtcaccaac ttgttcacgg attttttcta
     9361 cttgcatatc gataaagtta tccattgtcc agttaccttc acagtgacaa acatcaaagg
     9421 caaagtggcg cagcaattcg attccgtatt cggaatgacg tacttctgca tggaattgga
     9481 taccataaaa attacgtgtt gtgtcttgga tagaagcaat cggacaatct ttgcttgttc
     9541 cgactgtttc aaagccttca ggaactttag ttaccaagtc accatggctc atccatactg
     9601 tttgttgttt tggtgtttct ttaaacaaga cagcttgatc gcttgttact tctaacaagg
     9661 ctttcccata ttcgcggttt ttagcaggct ctacggaacc gccaagtttg tacgtgatca
     9721 attgcatacc atagcaaatc cctaatacag gaatacctaa attgaagatc tcaggatcga
     9781 tcccaaatgc attctcatca tatacactgt ttggtccgcc agaaagaatg attccctttg
     9841 gattcatcgc ttttacttct tctgcagtaa tgcggtggct caataattcg gaaaagactc
     9901 caagatcacg aatacgtctt gtgatcaatt ggttatactg actaccgtag tctaatacga
     9961 taatcttttc aacgttcgtc atatcggcaa cgtttgtcaa atttattacc cctatccctt
    10021 taaattttat ctcaaaatag tcaaactatt ttaaaatgct aatattttcg catgaaaatc
    10081 gaatcgatga tatgattttc agttttatgg agaattatat cggctcttcc tcgtgtaggc
    10141 aagatatatt cctgtaaatt tttcaaattc acatttttcc atacatcttt tgccatttta
    10201 aaggcttctt cacgatctcc gatagcaaaa cgataataat aattctctgg attttggaaa
    10261 gccgtatcca gtaacgcacc aaaacgatcc aaataccatt tttcgatcag cacgggatcg
    10321 gcatcgacat agacagaaaa atcaaaaaag tcgctgacgt agatttgctg attcgcaggt
    10381 aattgaagcg tattgatccc ctcaacgatc aagatatcag gctgctggat caattcgtac
    10441 ttgtctggaa tgatatcata cacatcatgt gagtaaacag gtacttttat ctcttcctga
    10501 ccagatttta cacggttcaa gaaatcgatc agcatctcca tatcataact ttcaggaaat
    10561 cctttacggt ccatgattcc acgctctttt aatatacgat ttggataaag aaatccgtca
    10621 gtcgtgatca gctgaacgtt tcttcgtttg aaggtacgag acaaaatcgt ctgcagcagt
    10681 ctggctgttg tactttttcc aacggctaca cttccggcga tcccgataat aaaaggcggt
    10741 acttctacgt atttatgaag aaataaacct ttactcaaga acaaagattc aaattctttc
    10801 atataaagat aaatcagatg agcaagaggt acatagatat ctcgaacatc ctgcatggaa
    10861 atgcggtcat tcaaactttt gatattatct agttcatctt gtgtcaaagg tgcttgccca
    10921 ttacgataaa attctcgcca ttcttctctt gccacacggt agtagttcat tggatcattc
    10981 atattagcct cctgcgttct cccatcaatg gaactatttt aacacaaaat aaacgcaaac
    11041 cccaccactt aagagagatt gccgatcttt ttgtataatc tttataatag aaagaaacgg
    11101 agtcttattc ttgacttgcg cacggataca taaaaggata gactgttgtc atgaaagaaa
    11161 tgagaaggat ggaagacatg acaaatcatt actattctga acgcccagat acggcgcacg
    11221 attttgaaca atgggctttt gagttaaaag gcagaacctt tcaatttgta acagattctg
    11281 gtgtattttc acgtgaaaca gtggattatg gttcacgtgt cctgattgat gctttcgatt
    11341 gggaagagtt acctgatgaa ggaaagatct tagatgtggg atgcgggtat ggaccgattg
    11401 ggttagcttt ggcatttgcg acacagcggt ttgttgaaat ggtcgacatt aatgaacgag
    11461 cggtaagtct agcgcaagga aacgcaaagc gtaaccaaat cgaacatgtt gatatccatc
    11521 aatcgaatat ctatgaagca gttcatgaag aaacctatgc agctatcgta agcaatccgc
    11581 cgatccgtgc tggaaaaaaa gttgtacatg aaattttgac aggcgcatat cctcggttga
    11641 agaagggcgg tacactgaca attgtgatcc agaagaaaca aggagcgccg agtgcgcaaa
    11701 agaaaatgga agaaacattt ggtaatgcag aaatcgtcac aaaagataaa ggatattata
    11761 tcatcaaaag tgtgaaagaa taactagctg aaaaatagtg gagcgacgaa agagtggaac
    11821 tgggcgtgca tgtacgggta cgtatcagtt ctttttttgt tgagaagttt ttaaaaacaa
    11881 agaactattt tttcttcaaa aagaaatagt aggaacagag tcgttgtttt ttacgataaa
    11941 ataaataaga tacagaactt gtatagaagg ctgccaagtc ggtagataaa ggaggttttt
    12001 atcaaaaaac atactttcct tttttctcta ttcttttctt gggggttttg gtacactgat
    12061 agggaattta gatagaaggg agccaatagg atgaagctga ccatcagaga tatcgcagaa
    12121 atggcaggcg tatcagtaac aactgtctca cagattttga ataacaaagg aagcagattt
    12181 agtgataaga caagaaaaaa agtgttgtcg atcgtgaatg aacatcatta taagcccgat
    12241 tatttcgctt caaatgtgat caatcgacat tcaaagacca tcggaatgat cgtccctgat
    12301 gtcactgatt tcttcttctc caaactgatc gaaggtgtag agagctattt gaatcctttg
    12361 ggctatgtga tcatgttatg caattctcgt catagccaag aaaatgagat caagtattta
    12421 caagagcttt cccaccgctc agtggacgga atcttgctgg ccacaccaaa tattttacct
    12481 gagaaatatg cattagacag cggtttttat caaaaaatgc caatcatttt aatcgatcgc
    12541 ggattgaatc gtcgggataa cggacggctt atcgtaaagg aatatgaggg cgcctatcaa
    12601 gctgtttcgc tgtttattga aaatggccat acgaagatcg gcatgctgaa ggaaaccact
    12661 ggatactatc aattagaaga acgtttcaac ggatatcgtc atgcgctgaa agatcatggc
    12721 ctgcctttta atgggaaatt tgttgaacat ggagagttga ctgtccaagg tggatatact
    12781 gcatcaaaaa aattactcaa acataaagat atcacggcta ttttttgcgg gaatgatgcc
    12841 atggcgatcg gatgctatca ggcgatcgat gaattgggca aaaaaatccc agaagatatc
    12901 tcagtcatag gattcgatgg attaaagctg tcagaataca tgattccgca attgacgaca
    12961 gtgcagcagc caagttttga tattggattt tatgctgcac gtttcctgat cgatacgatc
    13021 gaatttcctc aaagaaaagt tccgaacaaa gtgttcgaaa caaaattaat tattcgtgag
    13081 agcgtaaaag tattgacaaa gggctaactc ggcggtatat tgcttatgta agcatttaca
    13141 aaggctagtt agtgcttttt ttatttttag taaaccagtt tactaaagtg gtttaccttt
    13201 cctaaaaata atgtataata ccgaatgaag acaaggagga tcaggcaatg cgaatggtgg
    13261 atctgattga aaaaaagagg gatggaaacg agctgtcgaa agaggaaatc gagtacatcg
    13321 tcacgaacta tacgaatgga aagattccag attatcaagt cagtgcatta ttgatggcaa
    13381 ttttttatca agacatgaca aatgaagaaa tcacgaactt aacattggcg attgctaatt
    13441 ctggtgatgt catcgatttg agttctcttg aaggaataaa ggtagataag cattcgacag
    13501 gtggcgttgg tgacacgacc acattgattt tagcccccct agtagctagt gtcggagtga
    13561 cagtggctaa aatgtctgga cgcggtctag gttacacagg tggtacacta gacaagctag
    13621 aagcaattcc cggatttcag atcgagcttt cggatgaaga atttgtacgc attgttaatg
    13681 aaagtaaagt agcggtaatt ggtcaatcag gaaacttggc accggcggac aaaaaattgt
    13741 atgccttgcg tgacgtcaca gcgaccgttg attctcttcc gctgattgcc agttcgatta
    13801 tgagtaaaaa aatcgcggca ggagcagatg caatcgtttt ggatgtgacc actggagacg
    13861 gtgctttcat gaagaacatc gaagatgcaa gacgtctggc aaagaccatg acgagcattg
    13921 ggaaactggc taaccgagaa acagtggcgg ttatctcaga tatgtcagaa cctcttggcg
    13981 aagctatcgg aaatagtcta gaagttgtcg aggcaatcga aacattacaa ggaaatggtc
    14041 cagaagatct agtagaaatg tgctacgcct taggaagcca aatggttgtt cttgctggca
    14101 aagctaagac aaccgatgaa gcaagaacgt tgcttcaaga agctctggaa tcaggtaaag
    14161 cgttagcaaa attcaaagaa atgatccaaa atcaaggggg agacccagcg atcgtggaac
    14221 atccagaacg aattttgact gcacgctaca caatggagct tcctgctaaa caaagcggag
    14281 ttgtgtcaaa aatcgtggca aatgaattag gaattgctgc aatgatgcta ggtgctgggc
    14341 gtaaaaccaa agaagaagat attgatcacg ctgttggatt gaaactgcat aaaaaaattg
    14401 gtgacactgt gacaaaaggt gagtcactat tgacgatcta tagtaacgac gaagaaatca
    14461 cttctgtcat tgaattatta tataaaaata ttgaaattgg tgaatcggca atgaagccaa
    14521 cgttgattca tgacatcatc acagaataaa ggaaaaaagc ggactttacc gttttaaaga
    14581 aaaggggaaa agaaatggaa ctaaaccgaa tgatcgacca tactattttg aaagcagacg
    14641 catctaaaga agctgtgatg caaattatcg aagaagcaaa aaaataccat ttttattctg
    14701 tctgcatcaa tccagcatgg gttgcgctag cgaaagaaca attacaaggt gagccagtag
    14761 ccgtatgtac agtaatcggg tttcctctag gagcaaacac acccgagaca aaagcatttg
    14821 aaacaacaga tgccatcaat aacggtgcag atgaagtcga tatggtcatc aatatcggtg
    14881 ctttgaaatc aaaggatgat caacaagtcc aaaaagatat cgaagcagtt gttgaagcag
    14941 caaaagatcg tgcgcttgtc aaagttatta ttgaaacatc gttattagat agagaagaaa
    15001 tcatccgagc ttgcgaaata gcaaaagctg caggcgctga ttttgtcaaa acatcaactg
    15061 gtttctcaac aggcggagca aaggtagagg atgtccgttt gatgcgtgaa actgtaggac
    15121 cagaaatggg tgtcaaagct tccggcggta tccataacga agaagaagca atggcaatga
    15181 tcgaagctgg tgctacaaga atcggaacaa gcgcaggagt agcaatcgta tctggttcaa
    15241 ctggtgaagg ctattaattt tttcaaagga gaagctcatg gcagaactca aacaagaatg
    15301 gatcaacaca gctattgaag cgttagataa agcctatgtt ccttattccc attttccggt
    15361 aggcgcttgt ctcgtaacgg aatcaggcaa gatttatcaa ggcatcaaca ttgagaatgc
    15421 atcatttgga ttaacgaatt gtgccgagcg cacagctttt ttcaaagcag tatctgaagg
    15481 agaaaaaaca tttacgcatc tagtcgtagc ggggcacacc cccgatccta tctctccttg
    15541 tggtgcatgt cgacaagtaa tggcagaatt ctgttcccct gatatgccgg ttacgctagt
    15601 aggagacaat ggtgtgacga aggcaacgac cgttcgtgca ctgctgcctt atgcatttac
    15661 tgaaaaagat ctataactca tgttcattca gtcagctgac tgttgaaaaa taaaacaatt
    15721 attttaggag gctttacaga aatgaaaaaa gcaaaattat ttggtttagg tgctgtcgca
    15781 ctagcagcag ggttattttt aggtgcatgc ggcaacaacg gctctactga ttcatccggt
    15841 ggcaaaagct catcagacac aacaactgca gcattgatca cagacacagg tggtgtagac
    15901 gaccgttcat tcaaccagtc agcttgggaa ggactagaaa aatgggggaa agatcaagga
    15961 ctttcacgag gaaatgatgg cttccaatat ttccaatctt caaatgaatc agattacatc
    16021 ccaaatattg accaagcatt gaatgctgga ttcaaaacga tttttggtat tggttataaa
    16081 ctaaaaccag cgatccaaga acaagcaaca aacaatacag gtacgaactt tgttattatc
    16141 gatgatgtca tcgatggatt agataacgtt gtatctgcaa ctttcaaaga caacgaagct
    16201 tcttatcttg caggtgttgc agcagcttat acgactgaaa caaacgtagt cggctttatc
    16261 ggcggtgtaa aaggtgaagt aatcgatcgt tttgatgctg gattcaaagc cggtgttgat
    16321 gcaggtgcga aagaattagg aaaagaaatc aaagtattga atcaatatgc tggtgacttc
    16381 tctgctccag ataaaggacg ttcaattgct caaggtatgt atgcacaaaa cgcagatatc
    16441 atcttccatg cttcaggcgg tacaggtaac ggtgtattcc aagaagcaaa atcattgaac
    16501 gaatcaggcg acaaaaaagt ttgggttatc ggtgttgacc gcgaccaatc agacgaaggc
    16561 gaatacacat taaacggcga aaagaaaaac ttcacattga catctacact gaaagcagtt
    16621 ggaacagtag tagaagattt ggcacaaaaa tcagcggacg gtaaattccc tggcggcgaa
    16681 cacactgttt atggattgaa agaagacggt gttggtctaa cagaaggaca actttctgac
    16741 gaagcgaaaa aagcagttga tgaagcaaaa gaaaaaatca tttcaggtga cgtaaaagtt
    16801 ccagaaactc ctgaagaaaa ctaaaaccat ttctatagcc ttgttagaca catgtttgac
    16861 aaggctatgg tttgattaga acaagaattg ttcatttatc caagctgcct tgtgacagtt
    16921 tggataaggg aacaactccc tgaagtaatg tttgtttcaa aagaagaacg ctcactaagc
    16981 gtgaatctta gtcaatcgtt gccctagata gaaatcgtta ggatgtgaaa aaaaggtggt
    17041 tcaagaaaat attgtcatag aaatgcagaa tattaccaaa gaatttggaa cattcaaggc
    17101 aaatgacaac atcaatttac aagtaaaggc aggagaaatt catgcgttgc ttggagaaaa
    17161 cggtgctggc aaatctacat tgatgaacgt gctttccgga ttattagagc cgacatcagg
    17221 gaaaattttg atgcgtggga aagaagtaaa gatcacaagt ccgaccaaag ccaaccaatt
    17281 agggattggg atggtccatc agcactttat gcttgttgat gcctttactg taacagaaaa
    17341 catcgtgttg ggaagcgagc ctagtcgcgc agggatgctt gaccataaaa aagcacgaaa
    17401 agagatccaa aaagtttctg aacagtatgg attgtcagtc aacccagatg cttacgttcg
    17461 tgatatttca gttggaatgg aacaacgggt agaaatttta aaaacacttt accgaggagc
    17521 agatgtactg atttttgatg agccgacagc tgtattgacc cctcaagaaa ttgatgaatt
    17581 aatcgtgatc atgaaggaat tagtcaaaga aggcaagtcg atcattttga ttacgcataa
    17641 gttagatgaa atcaaagcag tagctgaccg ctgtacagtt atccgccgtg gaaaaggaat
    17701 cggtacagtc aacgttaaag acgtaacctc acaacaatta gccgatatga tggttggaag
    17761 aacggtttca ttcaaaacga tgaaaaaaga agcgaagcct caagaagtcg ttttgtctat
    17821 tgaaaatcta gtggtgaaag aaaatcgtgg attagaagcc gtgaaaaact tgaacttaga
    17881 ggttcgtgct ggcgaagtac ttggtatcgc tggaatcgat ggaaacgggc agtcggagtt
    17941 gatccaagct ttgactggtt tgcgaaaggc agaaagcgga catatcaagc taaaagggga
    18001 agacatcact aataaaaaac cccgaaaaat cactgaacat ggtgtaggac acgtgccaga
    18061 agaccgtcat aaatacgggt tagtcctaga tatgacatta tctgaaaata tcgcactaca
    18121 aacctatcat caaaaacctt acagtaaaaa cggcatgctg aattattcag taatgaatga
    18181 acatgccaga gaattgatcg aagaatatga tgttcgaaca acgaatgaac ttgttcccgc
    18241 aaaagcttta tcaggcggaa atcagcaaaa agcaattatc gctcgtgaag tcgaccgaga
    18301 tcctgatctg ttgattgttg caaatccaac tcgtggactg gatgtaggtg cgatcgaatt
    18361 tattcataaa cgtctgatcg aacaaaggga caaatacaaa gcagtgttac tgatcagttt
    18421 cgaattagaa gaaattttaa atgtttcgga tcgtattgct gttatccatg aaggagaaat
    18481 tgtcggtatc gttgatccga aagaaacatc tgaaaatgaa ttaggtctat tgatggcggg
    18541 ctatacctta gaagaagcac gaaaagagtt agaaaagggg gctggcgcac atgaatgatc
    18601 gcagcgaaaa attccgtaat ttattagtgc ctgtactttc agttgtttta ggattgatct
    18661 taggcgcgat attgatggct gcttttggtt ttcagcccat ccaaggttat tcttctatgc
    18721 tagatgcagc ccttggttcg caaagaggga taggtgaaac gttaaggcaa gcaacgccgt
    18781 tgatttttac agcattaggt ttttctgtag ctaactcagc tgggtttttc aatattgggc
    18841 tttctggaca agcactttgc gggtggatcg tcagtgtctg ggtggcactt gcgtttccag
    18901 atctgccaaa agttgttttg cttccgttat gcgtgatctt aggtgcctta gctggtgcga
    18961 tggcagcggc tgttccaggt ttacttcgag cattttttgg aacaagtgaa gtgatcgtaa
    19021 caatcatgat gaactatatc ttattatacg taagcacatt tgctttacat gaagtgatgc
    19081 ctgaaagcta tcgctcaagt ttggactctt ccaatatgat cagtcaaaat gcctcactgc
    19141 ggttaccatg gttaacacaa gcttttggcg gctctcgcgt aaactcagga ttatttttag
    19201 caatcatcgc gcttattttc gtttggctgc tgatgaagaa aacgacttta ggatttgaaa
    19261 tccgttctgt tggattgaat ccttttgctt ctgagtatgc aggaatgagt agtaaacgta
    19321 cgatcgtttt gtcgatggtc atttctggcg ctttggcagg gcttggcggt gtggttgaag
    19381 gattaggaac gtatcaaaac ttctttgttc aaacgacttc gctatctatt ggatttgacg
    19441 gaatggctgt ttccttgctt ggttctggat cagcaatcgg tattctttta tcagcgatct
    19501 tgttcagtat tttgaagatc ggtggacttg gcatgcagac aggagcaggt gttccgtttg
    19561 agatcgtcaa tgtatcgatt gctttgatta tcttctttgt cgggatcaac ttcctgattc
    19621 gtttcgtcat ggctaaagtc ttccaaggga aaaaacaaga agagatcgtt gcgacaatag
    19681 aatcgaaacc aacgaatcaa aaccatgaag ggggcgaact ataatgtcga ctatcgaatt
    19741 aattgccttg atccttactt ctacactggt ttattcaaca ccgctaattc taacgtcact
    19801 aggcggaact ttttctgaac gaagcgggat cgtaaacgta gggctagagg gaatcatggt
    19861 catgggtgct tttagttcca tcgttttcaa cttgacgatg agtccatcac ttggttctat
    19921 gacaccatgg atcgctattt tagtgggtgg cgtcgtaggt atcctatttt ctctgattca
    19981 cgcagtagca acagtcagtt tgcgtgctga ccatattatc agcgggacag taattaatct
    20041 gatggcacct gctttaggtg ttttcttgat caaagcatgg tatggtaaag gtcaaactga
    20101 taacatcacg cagaatctgg ggtatttttc tttcccagga ttagcagata ttccggtcat
    20161 tggaccaatt ttctttaaaa atacattctt acctgcttat tgtgctattt tgattgctgt
    20221 cctagcttgg gtgatcatct tcaagacgaa attcggcttg cgcctccgtt cagttggtga
    20281 aaatcctcaa gctgccgaca cattaggtat caatgtatat gctatgcgtt attcaggcgt
    20341 actgatttct ggcttgttag gcggtatggg cggtgctgtt tttgctcagt cgatttccgg
    20401 taacttttca gctggtacga tcgttggaca agggttcatc tccatggctg ctatgatctt
    20461 tggtaagtgg aatcctttag gggcaatggg tgcctcattg ttctttggtt ttgctcaaag
    20521 cttgagtatc attggcgcac aattaccagt tatttcttcg attccgccag tattgctgca
    20581 aattgctcca tatttgctga caatcattgt gctggttgtt ttcttaggga aagcttctgg
    20641 tccaaaagca aacgggaaga actatatcaa atcaaaataa tcttttagcg aataaaaagg
    20701 gtgggttacg ggaagtgttt ttcgtctcgc cctttttgtt ttaaaggcaa taaaaataaa
    20761 aagaaagaag gaataatcat gtttaaacgc gtacatctga tcgtcatgga ttcagtagga
    20821 attggagaag caccagatgc cgataagttc ggtgatgttg gttctgatac attaggacac
    20881 attgcgaaag aagcaggatt gaacgttcca catttagagc agcttggttt aggaacgatc
    20941 cgtcctcttg aaggtgtgga atcagtgaaa gatcatcaag gctatgcgac gaaattagaa
    21001 gaagtttctg tagggaaaga tacgatgaca ggccactggg aaatcatggg attgaatatc
    21061 aaaactccat ttcgtgtgtt tcctaatgga ttccctgatg atctgatcaa acaaatcgaa
    21121 gaattttctg gccgtaaagt cgtatgtaac aaaccttata gcggaacagc tgttattgac
    21181 gattacggtg aacaccaaat gaaaacaggc gatttaattg tatatacttc tgccgatcct
    21241 gtccttcaga tcgcggcaca tgaagaaatc attcctttag aagaattata tcggatttgc
    21301 caattcgttc gtgatataac aaaagatgat ccgtatatga ttggccgaat cattgcacgt
    21361 ccgtacgtgg gtgaaccagg agacttcaca cgaacaagca atcgccatga ttatgcgttg
    21421 aatccattcg gacacacagt ccttgattct ttgaaagaag caggaaagga cgtgattgct
    21481 gttggaaaga tcaacgatat tttcaacgga caaggaatca ctgaatctgt ccgcacgaaa
    21541 agcaatatgg atggcgttga ccagctgctg aaagttatga aaaacgattt ttcaggaatc
    21601 agctttacca atttagtaga ttttgatgca ttatacggtc atcgtcggga tgtagtcggc
    21661 tatgcgcatg cgattgaaga atttgactta cgaattccag aattgcttga agcgatggaa
    21721 gaagacgact tgctaatgat tacagccgat cacggaaacg atccgacgtt tactggtacc
    21781 gatcatacgc gagaatatgt accgttattg gtttacagta aaaaaatgaa agaacaaggg
    21841 gcattgcctc aaggatatta ttcagatatt tcagcaacga ttgctgagaa ctttagtgtt
    21901 tcttcgactg aaaatggcga aagcttcttg aaattattaa aataatcttt ttaaatagga
    21961 gaaagcaaat gaccaagtta agcgagatgt tacaagaaac gacccagttt atccttgata
    22021 aaggagtaaa agaaattgat tttggtttga ttctaggttc aggattaggt gaattagcag
    22081 atgaaatcga agatgctgta atgatttctt atgatgagat cccgttcttt cctgtttcga
    22141 cagtagttgg gcatgcagga aagctagttt atgggtctct ggcaggcaag aaagtgttag
    22201 ccatgcaagg gagattccac tactatgaag gtcattccat gcaaacagtg acctatccag
    22261 tacgtgtgat ggccggacta ggggcccatt cagtcattgt gactaatgca tgtggtggtg
    22321 tcaacgaatc atttgtacca ggagatttga tgctgattac cgatcatatc aattttactg
    22381 gtgaaaatcc tttgatcggt ccgaatgaag atgcaatggg ccctagattt ccagatatga
    22441 gtcaagctta tacgcctgac tatcaagcaa cagcaaaagc agcagcagaa aaactaggtt
    22501 tggatcttaa agaaggcgta tatatgggct attctggacc aacttatgaa acgcctgcgg
    22561 agatccgaat gtctcggaca ataggagccg atgcagtagg gatgtcgact gttccagaag
    22621 tcatcgtagc agctcacagc ggattaaaag tgttaggaat ctcttgtatt accaacttag
    22681 cagcaggtat gcaagcgaat ctgagccatg aagaagttgt agaaacaact cagagagtca
    22741 aacaatcttt taaagcattg gttaaagaaa cattgacatt attgtaatag gaggaacaat
    22801 aaaatgagtg tgcatattga agcgaaagaa ggcgagatcg ccgataagat tttacttccg
    22861 ggagatcctt tgcgagctaa atatattgcg gagacttttt tggaagatcc agtttgttac
    22921 aatcaggtac gcggtatgtt aggctttacc ggcaaatata aaggagaacg tatttctgtt
    22981 caaggaacag gaatgggaat gccatcagcc accatctatg cccatgaatt gatccagtcg
    23041 tatggtgtaa agaaattgat tcgagtaggt acatgcggtg cattgtcaaa agacgtccat
    23101 gttcgtgatt tagtactagc acaaggtgca gcgaccagtt cttcgatgat cgaaaaaaat
    23161 ttccaagcct ttcattttcc tccaatcagt gatttcaatc tattactgaa agcatatgag
    23221 atagctaaag aaaagggcta tacggttcat gtaggaaatg ttctttcgga agattctttc
    23281 tacaaagatg atttgacaga gacgttccaa ttagctgaac ttggcgtttt aggagtggaa
    23341 atggaagcag cggctcttta ttacttaggc gcgaaatacc atgtgcagac attaagtttg
    23401 atgaccgtta gcgaccattt gatcaccggt gaagaaacaa cagctgcaga acgtcaatct
    23461 acgttcaatg aaatgatcga agtaggattg gaaacagcga tagcagaata agaaggaaat
    23521 gaaaaagctg ccctgcatta agtaataaga acatccaagc aaaaatagct cctcatgttt
    23581 ttgacttggc tggacttatt attgcaaatg taagcttttg aacaccgttt accaagaggt
    23641 tgtgaatctg ccgtttaact ctgagtcaca aggaacaatt tcaaaaaaca gcttttcatg
    23701 tttgatgaat attgtgactt gtgaccgaga agttggcagg agaaaaccgt ttatacgaaa
    23761 aaagggactg tgacaaatcg tgtcacagtc ccttttttat agtgtttttt ataggtagta
    23821 ttttttagca actgttaagt catcatttaa ttcataaaca agtggttgac ctgttggaat
    23881 ttcaagatcc atgatgtctt cgtcagagat accttcgata tgtttagcta gggcgcgtaa
    23941 tgagttacca tgtgcagcta ctaaaacagt tttgttgtct agtaatgctg gagcaatttc
    24001 atcttgccag aatggcaaag cgcgttctaa tgtcactttc aagttttctc caccaggaat
    24061 atcgcgtttg tctaacattg cgtaacgacg gtcatttgct gcagaacctt cgtcagtttc
    24121 ttccattaat ggaggaagag tatcgtaaga acgacgccag atgtgcactt gttcgtcgcc
    24181 gtatttttca gctgtttctt ttttgttcaa accttgtaat ttaccatagt gacgttcgtt
    24241 taagcgccat gatttgattt gtggtaccca aagttgatct gaatattcta agatcaagtt
    24301 acatgttttg attgcacgag ttaaaacaga agtgtaagca acatcaaatt cgattccagc
    24361 ttctttgatt ttgcgtccgc cttcttttgc ttcttcgatt ccttctggtg ctagatttac
    24421 atcagcccaa ccagtaaatt ggttcaatgc attccattca ctaagaccgt gacgagaaaa
    24481 aactaatttt ggcatgttta gctctccttt taagataggt ttatatttct gaaattttca
    24541 gttctgtttt attgtacaat tttttggaag agatttccat cgaaaaatta gataagattc
    24601 tatgagaaaa caagtagaga atataaaaaa acgaacagtg cccacgcaac tgttcgtttt
    24661 taggtattag atgcataatt gctcgatttc tttttcaggt aaattgatat atttataaca
    24721 tgttccaact gaaacaccgc attttgaaga aataaattgg atcgtttctt ttttttcata
    24781 atagagacgt cggatttttt tgatcgtttt tgcatcgatt tttggtcttc cgccgatttt
    24841 tcctttttta cgagcttcat ctaatccaac taatgtacgt tctttgatca atgcgcactc
    24901 catgtttgct aggttttcca ttaattggaa atagattttt cccatttcgc gcgtatcgat
    24961 tccttcatca agactaatca agtgcagccc gcgatctttg aataattgcg tgagttctgt
    25021 taattgccgc gtagatttgc ctaatcgatg aagttggcaa atgactagtg catcgccttg
    25081 ttgcatgtca gcgatcactg actccaaatg aacagcagta gaatcatttt gttccacttc
    25141 atatgtctca tggaaaattt cttgacaacc aaagtcagat aattgatcaa cctgagttgt
    25201 taaatcaacg tcatttatgg ttgtgcgtgc ataaccaata attttcatgg tgattccttt
    25261 ctagcagtga ttttctaact ggatataaca gtaaaaatgt agcataaagt acgtcaaaaa
    25321 gatagttttt tcgcaaattt tccgctgtct ttttttattg gatgatcaag cagtttttct
    25381 ttatttacga cggattgcgt caagaatctc aacgcctttt tctgagccga caactacttt
    25441 agaaaccatg tttaggaaaa gcccatgttc tactacccca acaagttcat ctaaataggt
    25501 agctaagctt tctggctgtt cgatgacttc tagatgcaga tcaatgatgt aatgaccacc
    25561 atctgtggtt aagacttctc cgttttcgtc tgtacgcaag acgggttgga atcttttttc
    25621 ttcaaaaata tgaagtagct gttgggagcc ataagggatc acttcaactg ggagtgggaa
    25681 cttcccaagt ttatcgacta atttagaaga atcaacgatc caaatcgttt cttttgagta
    25741 cgtagcgact attttctcga aaagcaaagc agcgccgccg cctttgatcc cttgaaaatc
    25801 agcactgatt tcatcagcac cgtctattgt caaatcgact acggggactt catcaatact
    25861 ctttaacggt attcctaatt tttccgcttg ttcttttgtc gcatttgaag tagtaactcc
    25921 tgtgatacgt aaaccttctt cacgcatacg gcgaccaatc tcttctacca tataataggc
    25981 ggttgaaccg gtcccgagac ctacgatcat cccgtccttt acgaatttcg cggcttcaat
    26041 gccagctaat tgttttaaat tcatctttgc gtccaccttt ttttagtttg agcatcgtgc
    26101 tttcctcact attttagcgt gatttacggt aaaaagatac cattcttttt tattccaata
    26161 aagctttttc aaaaaaaatt gcatctcttg ttgacatgtt ttttcattcg tgatattcta
    26221 acaaaggtgc tttatctaca ggtttctgtg aagaaacgtg ctgactgttt atcaaagcat
    26281 atttgataag gatgcagaca ttgcatttat tttttatcac aaaaaaagaa ccacctggat
    26341 gtgtggaact agacgcaaat cgtgggaagg aggaaacaag gaatgcctac aattaaccaa
    26401 ttagtacgta aacctcgtaa atcaaaggtg gaaaaatcta attcacctgc tttgaacaaa
    26461 ggatataaca gctttaagaa aactcaaact aacgtaaact cacctcaaaa acgtggggta
    26521 gcaactcgtg tgggtacaat gacacctaaa aaaccgaact cagctttacg taaatatgca
    26581 cgtgttcgtt tgtcaaactt aattgaagtt actgcttata tcccagggat tggtcataac
    26641 ttacaagaac acagtgttgt attattacgc ggtggtcgtg taaaagactt accaggggta
    26701 cgttaccata tcgttcgcgg tgctttagat actgctggtg ttaacgaccg taaacaaagc
    26761 cgttctaaat acggaactaa aaaacctaaa gcttaatttt aattattaaa caaatgaaac
    26821 ttgcttctac tatatagaag taattactat gaacaatatt tcggaaggag gagttacgga
    26881 tgccacgtaa aggtcctgtt gcaaaacgtg atgttttacc agatcctatt tataactcaa
    26941 aattagtaac tcgcttgatc aaccgtgtaa tggttgacgg aaaacgcggg attgcagcta
    27001 acattatcta taatgccttt gacttgatca aagaatctac aggtaacgat ccattagaag
    27061 tgtttgaaca agcaatgaaa aacgttcaac ctgttcttga agttaaagca cgtcgtgttg
    27121 ggggttcaaa ctaccaagta ccagttgaag ttcgccctga acgccgcgtt actctaggtc
    27181 ttcgttgggt agtaaactac gctcgcttgc gcggtgaaca cacaatggaa gaacgcttag
    27241 caaaagaaat catggatgct gcaaacaaca caggtgcttc tgttaaaaaa cgtgaagaca
    27301 ctcataaaat ggctgatgcc aaccgtgcgt ttgctcacta tcgctggtaa gattctctct
    27361 gtttggtcgg cttttataag tcgacctcag atagtgtcct tatttttagc aactagatag
    27421 taaagagagg agaaacaagg agaatgacca gagaattttc tttacaaaac actcgtaata
    27481 tcggtatcat ggcccacatc gatgctggta aaacgactgc tactgaacgt atcttgtact
    27541 atactggtaa aatccataaa attggtgaaa ctcatgaagg agcttcacaa atggactgga
    27601 tggaacaaga acaagaacgt ggtattacga tcacttctgc tgctactaca gcacaatgga
    27661 agggtcaccg aatcaacatc atcgacacac caggacacgt agacttcaca gttgaagttg
    27721 aacgttcatt gcgtgtactt gatggtgctg taactgttct tgatgcacaa tcaggtgttg
    27781 aacctcaaac tgaaacagtt tggcgtcaag caacaactta tggtgtacct cgtatcgtat
    27841 ttgcaaacaa aatggacaag atcggtgctg acttcttata ttcagtatca actttacatg
    27901 accgtttgca agcaaacgct cacccaatcc aattaccaat tggtgcggaa gacgacttca
    27961 caggaattat cgaccttgta acaatgaagg ctgaaatgta tacaaacgat cttggaacag
    28021 agatcgaaga aacagaaatt cctgaagaat accgcgaatt agctgaagaa tggcgcgaaa
    28081 aattggttga agctgtagct gaaactgatg aagaacttac tttgaaatac ttagaaggtg
    28141 aagaaatcac tgaagctgag ttaaaagaag gtatccgccg cgcaacagtt aacgtagaat
    28201 tctacccagt actatgtggt tcagcattta agaacaaagg ggttcaatta ctattggacg
    28261 ctgttcttga ttacttgcca tcaccgttag atatcccagc tatcaaaggg attgacccta
    28321 aaactgatga agaagtagaa cgtcctgcag acgacagcgc tcctttctca gctttagcat
    28381 ttaaagttat gactgaccca ttcgtaggtc gtttaacttt cttccgtgtg tactctggtg
    28441 ttttacaatc aggttcatac gtacaaaacg caacaaaagg caaacgtgaa cgtgttggtc
    28501 gtatcctaca gatgcatgcc aactctcgtt cagaaatctc tgaagtttac gctggagata
    28561 tcgctgctgc tgttggtttg aaagacacaa ctactgggga cacactatgt gatgaaaaga
    28621 gtctagttat tcttgaatcc atggaattcc cagaaccagt tatccaagtc gctattgaac
    28681 ctaaatcaaa agctgaccaa gataaaatgg gtgtggcttt acaaaaacta tctgaagaag
    28741 atcctacttt ccgtgctgaa acaaacgtgg aaacaggcga aacaatcatc gctggtatgg
    28801 gtgaacttca cttagatatc atcgttgacc gtatgcgtcg tgaattcaaa gttgaagcta
    28861 acgtaggtgc gcctcaagta tcttaccgtg aaactttccg tgctggcact caagccgaag
    28921 gtaagtttgt acgtcagtct ggtggtaaag gtcaatacgg tcacgtatgg attgaattta
    28981 caccaaatga agaaggtgct ggtttcgaat ttgaaaatgc gatcgtcggt ggggttgttc
    29041 ctcgtgaata cattccagct gttgaaactg gtttgaaaga tgctatggaa aatggtgtct
    29101 tagctggcta tccattagta gatatcaaag ctaaacttta cgatggttca taccatgatg
    29161 tcgattcaaa tgaaactgcc ttccgtgttg ctgcttctat ggcattacgt gcagcagcta
    29221 agaaagctaa tccagtaatc cttgaaccaa tcatggctgt agaagttgtt atccctgaag
    29281 attatttagg tgatgttatg ggtcacgtaa ctgctcgtcg tggacgtgtt gaaggtatgg
    29341 aagctcgcgc tggcggccaa caagttgttc gtgcgatggt tccacttgct gaaatgtttg
    29401 gttatgctac aactcttcgt tctgctactc aaggtcgtgg tacatttaca atgacatttg
    29461 accactacga agatgtacca aaatcagtac aagaagaaat cattaagaaa aacggcggaa
    29521 aagctgaata atttcttaaa accggatagt cctgcaaaga gattatccaa agagactata
    29581 tttttaatat agtttcgtgt aaaataatta tcgatgatat gggcatgtgg tgtaccttgt
    29641 gtacatcata tacctatcag acaaataaaa aatatattgt atttttagga ggacatttta
    29701 aaatggcaaa agaaaaattt gaccgttcta aaccacacgt taacattggt actatcggac
    29761 acgttgacca tggtaaaact acattaacag ctgcaatcac aactgtacta tctaagaaaa
    29821 acggcggcca agctatggct tacgatcaaa tcgatggtgc tccagaagaa cgcgaacgcg
    29881 gaatcacaat ctcaacagct cacgttgagt atgaaacaga tacacgccac tacgctcacg
    29941 ttgactgccc aggacacgcg gattacgtta aaaacatgat cactggtgct gctcaaatgg
    30001 acggagctat cttggtagtt tctgctgctg acggcccaat gcctcaaact cgtgaacaca
    30061 tcctattgtc tcgtcaagtt ggtgttcctt acatcgttgt attcttgaac aaagtagaca
    30121 tggttgatga cgaagaatta ctagaattag ttgaaatgga agttcgtgac ctattaacag
    30181 aatacgaatt ccctggtgac gatgttcctg tagttgctgg atcagctttg aaagctctag
    30241 aaggcgacgc ttcatacgaa gaaaaaattc ttgaattaat ggctgcagtt gacgaataca
    30301 tcccaactcc agaacgtgac aacgacaaac cattcatgat gccagttgaa gacgtgttct
    30361 caattactgg acgtggtact gttgctacag gtcgtgttga acgtggacaa gttcgcgttg
    30421 gtgacgaagt tgaagttgtt ggtattgctg aagaaacttc aaaaacaaca gttactggtg
    30481 ttgaaatgtt ccgtaaattg ttagactacg ctgaagctgg agacaacatt ggtgctttac
    30541 tacgtggtgt tgcacgtgaa gacatccaac gtggacaagt tttagctaaa ccaggtacaa
    30601 tcacacctca tacaaaattc tctgcagaag tatacgtgtt gacaaaagaa gaaggtggac
    30661 gtcatactcc attcttcact aactaccgtc cacaattcta cttccgtaca actgacgtaa
    30721 caggtgttgt tgaattacca gaaggaactg aaatggttat gcctggcgac aacgtaacaa
    30781 tggaagttga attaatccac ccaatcgcta tcgaaaacgg tactaaattc tcaatccgtg
    30841 aaggcggacg tacagttggt gccggtgtcg ttacagaaat caaagcttaa ttcacttaag
    30901 ttttaaagta aagcaacatt tattcggacg taatcgctcg gaacgaaggt cttaggatct
    30961 ttgttccgag ctttttt
//
LOCUS       DAPBCF010000029        30718 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.029, whole genome shotgun sequence.
ACCESSION   DAPBCF010000029 DAPBCF010000000
VERSION     DAPBCF010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.029"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            311..1090
                     /locus_tag="RD508_001647"
     CDS             311..1090
                     /locus_tag="RD508_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736251.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSYVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            1136..2080
                     /locus_tag="RD508_001648"
     CDS             1136..2080
                     /locus_tag="RD508_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7736252.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVAIVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            2096..2875
                     /locus_tag="RD508_001649"
     CDS             2096..2875
                     /locus_tag="RD508_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HDT7736253.1"
                     /translation="MEETINLEEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            2887..3585
                     /locus_tag="RD508_001650"
     CDS             2887..3585
                     /locus_tag="RD508_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HDT7736254.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3613..4377
                     /locus_tag="RD508_001651"
     CDS             3613..4377
                     /locus_tag="RD508_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HDT7736255.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQITAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            4422..5111
                     /locus_tag="RD508_001652"
     CDS             4422..5111
                     /locus_tag="RD508_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDT7736256.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            6338..7018
                     /locus_tag="RD508_001653"
     CDS             6338..7018
                     /locus_tag="RD508_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDT7736257.1"
                     /translation="MIGIEEKKGVQKDVTIDREENLRGHRFYWIGRRAQDIFFSALAL
                     IALSPVMLITALAIVIDDPGGSPIFVQDRVGRNGKLFKFYKFRSMCVDAEAKLEALLA
                     QNEMDGPVFKIKDDPRITRVGKFIRKTSIDELPQLWNILKGDMSIIGPRPALPREVEQ
                     YGDYERQRLFVQPGLSCYWQIAPHRNELSFEEWVELDVKYINERSFITDWKIIFLTLQ
                     AVLFGYGE"
     gene            7047..8360
                     /locus_tag="RD508_001654"
     CDS             7047..8360
                     /locus_tag="RD508_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDT7736258.1"
                     /translation="MNIILLSGGSGRRLWPLSNDIRSKQFIKLFKDENGEYESMIQRV
                     YRQITTVDPDAKVTIATSKSQASAIHNQLGDKASICVEPCRRDTFPAILLAAAYLHDE
                     LGVGDDESVAVCPVDPYVDNSYYEGVEALEKLVQQNTANLTLMGIAPTYPSEKYGYII
                     PESSNEVSTVKEFKEKPDKATAEKYLAQNAVWNAGVFAFKLGYLLEKAHAMVDFEDYR
                     DLYSKYETLTKISFDYAVVEKETSIQVMRYNGDWKDVGTWNMMAEVMADNIKGKAVMD
                     DTCVNTQIVNELNIPILAMGCKDMVIAASGDGILISDKERSGYMKPYVEKISTEVMFA
                     EKSWGTYTVMDVQEGSMTVKVSMQAGQKLSYHYHNSRDEVWTVVAGQGKAIVDGMKQI
                     LRAGDVVTIAAGCKHTIEAVTNLDIIEVQIGETISVADKYKSSLN"
     gene            9166..9933
                     /locus_tag="RD508_001655"
     CDS             9166..9933
                     /locus_tag="RD508_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HDT7736259.1"
                     /translation="MGIEGGYLMSRMRFMNTEIDNLTMGEVLVEVEKMIQDRRCGYVV
                     TPNVDHIVQLETGKELQDVYKNASLILTDGKPLIWISKFYKTPIKEKISGSDIFSLLC
                     KMAAEKGYTMYFLGAAEGVAAKAADNLMKRFPGLNVVGTYSPPYGFEKDEDEMFKIDS
                     QIKRANPDMLIVGLGCPKQEKFMFYNCDRLGVPVSFGLGASLDFEAGNVKRAPKWMSD
                     YGFEWLFRITQDPKRMAKRYLVDDLKIFKLALKYRKK"
     gene            9960..10961
                     /locus_tag="RD508_001656"
     CDS             9960..10961
                     /locus_tag="RD508_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HDT7736260.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFRENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSTELSYSRTERVTNIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALKGKYADKKKLVDKAIYLERVLCNEAGGWQDQIAAAYGGFNRI
                     NFNSDGYEVLPIIITPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAVLTDKNRDLDDFGRLLDLTWRLKKATGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQNAVRSAMSNLMYIPFEFENGGTQVIHYTPEMYIPK"
     gene            10984..12270
                     /locus_tag="RD508_001657"
     CDS             10984..12270
                     /locus_tag="RD508_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HDT7736261.1"
                     /translation="MKVVIMAGGKGTRISSVASDIPKPMIKIENKPVLEHEIECLRDQ
                     GFTDIILTVSHLGDIIMNYFGDGSGISPVTGQPFDVKIEYFLEKEPLGNAGALFRLKD
                     NLTEDFLLLNADAMFDVDFNRFVAYHREKGGLVTLFTHPNSHPYDSGLIIADKDGSVD
                     RWLVKEDSRPTYYRNRVNAGLHVISPAVLDVEINTPKIDLDRQLLKPLAGTGKMFCYD
                     SPEYVKDMGTPDRYYAVCEDFKAGRVKGKNLQNKQKAVFLDRDGTINQYVGFLRHIDE
                     FELIKGTEDAVKKINAAGYLAIVITNQPVIARGEVSFEELEEIHNKMETLLGYKGAYL
                     DAVYYCPHHPHKGYEEERPELKFDCECRKPKPGMLIQAATDFNIDLSQSWMIGDGEND
                     IKAGQAAGCKTALVGESEYGQDMTIATLSEFADKIC"
     gene            12304..12957
                     /locus_tag="RD508_001658"
     CDS             12304..12957
                     /locus_tag="RD508_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7736262.1"
                     /translation="MIDNRLQKHIDLLIKRYPTLEVIKQDIVDGYLIMEECYLNDGKL
                     LIAGNGGSAADSEHIAGELMKSFKTPRPVSREFADKLIAVDPVKGSELAKNLEYGLMA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRPGDVFLGISTSGNSKNVINATVVARA
                     LGMKVIGLTGAKGGELARVADVCVKAPETETYMIQEYHLPIYHCWCLMLEDKFFGNR"
     gene            12990..14195
                     /locus_tag="RD508_001659"
     CDS             12990..14195
                     /locus_tag="RD508_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7736263.1"
                     /translation="MNVLFITTQFPYPLDNGGKIGAYNGISVLSRDYDVTVLSFTEEP
                     QYVEEGVSFFREKFNSVKFENPVIHDVHIRNNPMKLVEALAIGYCLRQPYIVSKFYDS
                     KMLQLIDEKFSNNAYWDIIFIDYLNMQSYGQYIREKYKTQFGKYILKDHNIEYDLVLQ
                     EAESSRGLKKKLLQLEYKRTRKYEEAAVNRADYCFSVCDANTEVLKKINDNSYTMLPT
                     YEMLTGVKKNIEKNTILYLGNLSWKSNMQGLVWFLESIYPNIQQRIPDVKITIVGSGP
                     VGTDFSKYSGVDYRGYVKDISHIYDDQAVLIVPLLEGSGIRIKILEAFNNEIAVVSTL
                     VGCDTIGAKDGSELFIADNEKDFATAVVRLLEDMNLNEKVRKNAKLFLKEKYSLTARQ
                     DEFSAIINS"
     gene            14325..15650
                     /locus_tag="RD508_001660"
     CDS             14325..15650
                     /locus_tag="RD508_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736264.1"
                     /translation="MIVAAMSYHLTGNSNVASLIAVVGVVYAIVKACNNEYLAIWVMF
                     VLGSDIWGIVPYINIGSGVLHWSDFNVIVAIFLCLRFIKVKARSRYGIVYSVMLIFIL
                     IACVQSHSIYGQDVHTTLLTARELLVVISFWPIVKIVYSERITKNEFIDLVCKFTRWT
                     MCIYWFEWILVNMGFNITFLQTGARWGTRIYIDPIFIILYFFINLYAVIYKREGYNST
                     NKSIWNCIFSLLTFVIISQGRSGILYVVITSVIMLLISLKPSKIIRFGILGIALIACL
                     VSVTQIREVVISSFVESQSSDTGNIAYRIAEQDYFENKLEGHELFGVGIPNNHDARAV
                     EYSGKTIDFESKKYNPYYLEDLGAFEIRYRFGIIAYALYIVALAISIIDAGFRRDKSV
                     AAFAGMAFMVFMALNFNLLAYITARPFGFMISLILIEISAFNDEFIYIE"
     gene            15667..16797
                     /locus_tag="RD508_001661"
     CDS             15667..16797
                     /locus_tag="RD508_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736265.1"
                     /translation="MNLDRLKKIANMISPIIKVINAPLAYFSGKSDYMEKGILWPTVT
                     TYSNNSRKVIQYTTLPKNVDNMAQMQWAGESFEDICIVLQGPVLEDGDFTLNTVKMYN
                     KYYPKVKLVVSTWIGLSEETECKLREAGADVVLCKKPEKTGAYNINLQLTSAYEGVKM
                     AQKLGCSYALKTRTDQRLYANDVLKYFQTLLNIFPSSDCKVVNQRLIFTTYGKSFRYL
                     PFNLCDFLVYGETSELLKLYGIQRDNRASDFGKIIYTEEKEFNKKIFTLLEGKQGVSP
                     YDVFPDFDALYKKYMFAEYYIVYNYFLENIASNESYGDLMDAYYSYLKKYAVVADSEK
                     LLLYWPKYVQYNVKFENELDFYAKLDSKKWMDIYANYTPFSQ"
     gene            16823..17908
                     /locus_tag="RD508_001662"
     CDS             16823..17908
                     /locus_tag="RD508_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="HDT7736266.1"
                     /translation="MKIGIVTIVNGASFGNRLQNYATQKVLENNGYTVETINNCFDKE
                     STLSIVIKNAIYTLFKFIPHFKKSKSIWKRMYTFYQWDKQYIDYSHRKIDASKKNSFV
                     SIKNDYDYFLVGSDQIWNPKYAANKGFELLSFVPNEKRVSLSTSLGVPSIPSDLEKLY
                     VTEWNKFKSISVRENQAAKIIEDLTGTTAAVHIDPTLMLERSEWEAFQKKPDNIDENY
                     ILSFFLTNPPKDTVDVLDKVAKDLKIGVLTLDASWEYFQDITPNHFVYLISHARMIYT
                     DSFHCTVFSLLFGKPVVVFDRFDSEKMNSRLSTLLNKVNKAHFWVGKKADEAMIRAIA
                     SEPEYDIDKLMVSERECVKAYLKEYLQ"
     gene            17931..18746
                     /locus_tag="RD508_001663"
     CDS             17931..18746
                     /locus_tag="RD508_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736267.1"
                     /translation="MEHLSDCFGKMKIVTTSCAREYFKDDLDKSEYSCFVDSRAAMFF
                     AMGQALAKRRNVVVMLADELTSCYTALTECAFQQVDLIVFAFQTVRHEIDLASLKNCG
                     CNLINCSAQDDIDRVVSNTKGLNQTTVIKINMNCESDKDHICEYIDLPDIPVFFHGSL
                     YSPASKKKYEQYGQVSKYLGYLVGGKDAILIISHNEFLNDISVWINYYSFGEIQPKII
                     IFDSPNDYQYKWLCDLECSVAHSTNRFLSEDLALLQNNGISIVLRGDNYDIVS"
     gene            18730..20448
                     /locus_tag="RD508_001664"
     CDS             18730..20448
                     /locus_tag="RD508_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylase"
                     /protein_id="HDT7736268.1"
                     /translation="MISSVKNVQILVSLLKQHNIKDIVISPGSRDFQLVHSVETDSFF
                     RTYTVVDERSAAFFANGLSMAIDKPVCVCCTSSTASSNYMAAAKDAFANGIQLVLLTA
                     DRDYRRLYQMEDQMIDQVDMYGAYVRSNVDIPIVKDSDDEWYATRKINEAILELNHGV
                     KGPVQINYQLMDLSAPFVETMPEYRKITRYQEDDLLSSVEIFKQKLLSKKRIMVLCGQ
                     QEENNLSALLEEFFIKYNTIIIKDNYSNIHGEHFIKTVLVTERMSVNAFIDYCPDLVI
                     TIGKHVWSFVKYTLRDKKLKFEHWRISEDGKIVDPFNKLTSVFQCSAEFFMETVTAGV
                     NSNNNLEYYNLWKTRLSKVCYPELVYSNFYAISELVKKIPDSALVHSSILNAARLYDF
                     VSDDKALLSFANLGADGIDGCLPTFLGQAEADKTRPAYLISGDLSFFYAMNSLCGDIP
                     DNAHIFLINNHSGSEFHTNFGKFYNGSLSVDKHIAAGHISNAKDWALENNIKYITADS
                     KESLKSGLDVFINTFDSPVLFEVFTDPDTDTSVLESFYSINKVITPKMYFRKALDIIK
                     KHLHIK"
     gene            20474..21310
                     /locus_tag="RD508_001665"
     CDS             20474..21310
                     /locus_tag="RD508_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7736269.1"
                     /translation="MAIKSYIKRLLLYIRHGDPKINLDVSYLSEGAMLAGKTVIITGG
                     AKGLGFAIAKSFIAQGASVIITGRDMDSLNNAKCQLGDMCSIRAFDITDAKMYRTFFE
                     DAYETFGRIDILLNNAGISLHEDGFMSVTEKTWDKQMDTNLKGVYFFTQEFIKFVKEK
                     NQMQANIIMMSSERGLCGDSIPYGLSKAAINSLVVGLSKKYISEGIRVNGIAPGVTAT
                     AMTGISEKGNLYNPATIGYRYFLPEEVAQVALFLASSLSNCISGEIIACDQGQYLSRN
                     WG"
     gene            21315..22748
                     /locus_tag="RD508_001666"
     CDS             21315..22748
                     /locus_tag="RD508_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HDT7736270.1"
                     /translation="MGILLKKYNSLSEPAKASIWFTLCNVLQKGILFLTTPIFTRMLS
                     TAEYGKYTIFISWYSIIAIFTTLNLSAGVYNKGLIKYENKYALTSSFLGLSSFISLCA
                     LMLYLPFRTVINGLLDLSTEFVILILIESIFEPAFLLWSVKERFDYKYQKLVLITVLM
                     AVLNPGLGIILILSFGEYAIWRVRAYVVVNVVVGMFIGIGILAKGKKLFDKEYWTYAL
                     RFNLPLIPHYLSMTLLNQVDRLMINSMVGASEAAIYSIAYTISSMMNIITTAINGSFI
                     PFTYKAIKDGVYEKIKSVANQLLVLIFVLCSFTMLFGPELIWVVGGEKYMDAVWIIPP
                     VAASVFFMFLYPLFGNIEFYYEKTNYVMFASCVGSIAKIISNYVSIPRFGYISAGYTT
                     LICYMLFSFAHYMFYKKILRENGIKEDMYNIKNIIFLSVLMIVLTIGMTILYFSTILR
                     YSIIIGLVIVAFLKRTQIMKILKNIKN"
     gene            22786..24426
                     /locus_tag="RD508_001667"
     CDS             22786..24426
                     /locus_tag="RD508_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HDT7736271.1"
                     /translation="MRLLIPSAKIVPEELHHLGKLPAIIYPINQKIVFDYLYDQYKDV
                     CSAIDIACYEKMDKVARRLDKYIKSKTVNIIQLKELGDLGRTIYDSLIGCDEPVIINF
                     ADTIINDNIYSLECDSFFYAEDYYSNTWTFFEEKDGDIISVLDKNELKEDDGKKHKLF
                     SGVFQIMDAQYFRECLRKALMSNVVNVNSFYQALQEYSKRYEFLSIKTNNWFDIGHAD
                     KYYNSKLEVKAREFNHISIDKDRSILRKISEDVEKFIGEIKWYLKLPAQVEYVRPRIF
                     EYSTSYINPYVSMEYYSYHTVHELFLYSDLTKKQWIDIFNRIRFVCSDFKRYSVSGDN
                     IQKSLKDMYLDKTFQRFNKLRKDPRFTEFFSSDIQINGVRYKSLDQIEALLSVSVPRE
                     LFDITQFNIIHGDLCFANIMVDNTFSFIKVIDPRGKFGDFDIYGDYRYELAKLFHSVD
                     GKYDFIIKDLFTIKYDPKKAIIDYIVQDRKRDYDLYEVFYSVFKDEIGSDLKKIELIE
                     ALLFLSMIPLHGESLNHQMAMLATGLEILGRVVPDIYC"
     gene            24514..24912
                     /locus_tag="RD508_001668"
     CDS             24514..24912
                     /locus_tag="RD508_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HDT7736272.1"
                     /translation="MFKDYAFVFDIDGTLCPIKKKDEKYEDLVPYANMVEKLRYYKEN
                     GAKITLFTSRNMNSYHGNLGVINANTAKILLAWLDKWEIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLSCTLDQLDEICKKSKLKSE"
     gene            24937..25653
                     /locus_tag="RD508_001669"
     CDS             24937..25653
                     /locus_tag="RD508_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7736273.1"
                     /translation="MTVIITMAGLGSRFRKVGYTVPKFMIEAKGKTLFDWSLDSLLDY
                     NSHVEKYVFVVRKEDDATVFIKEHCSLYGIENVEVVEIDYMTDGQATTCMLAIPYCAP
                     DNAIMVYNIDTYVEPGEMKYVDISGEGHIPCFHADGDHWSFAKLNEYGDVVEVREKVR
                     ISNNCTLGAYYFSSAKLYASLYEEYYADERHLEKNEKYIAPLYNYMIEKGMKVTISIV
                     DKSKVHVLGTPEELDVFLNE"
     gene            26885..27464
                     /locus_tag="RD508_001670"
                     /pseudo
     CDS             26885..27464
                     /locus_tag="RD508_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
     gene            27524..29176
                     /locus_tag="RD508_001671"
     CDS             27524..29176
                     /locus_tag="RD508_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDT7736274.1"
                     /translation="MDHNANYYHWLTNANAEIVEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLSDYLNKTYETPSVVVGYDSRIKSDVFAKVAADIF
                     AANGIQVHLWPELLPVPTVSFAIRYLKASAGVMITASHNPSKYNGYKVYGAGGCQITT
                     EAAAEILAEIEKLDIFADVKMGGDASRIASIQPEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEINEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKNAEGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PTDPVMVKTIVTMDLGERIASNYGVRTVDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLFDKLNEIYAKYGYCLNTLHSF
                     EFEGAAGFTKMQKIMVEFHKGLDMIGGKKVIETLDYSTGLNGLPKSDVLKYLLEGNCS
                     VVVRPSGTEPKLKTYISVSAESKEAAEVMEAVMAAELAEMFK"
     gene            29520..29885
                     /locus_tag="RD508_001672"
     CDS             29520..29885
                     /locus_tag="RD508_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HDT7736275.1"
                     /translation="MYYFQQSYLPAILNKAISIGDTGVHIFFFCSGFGLYLSYLKKPI
                     TLGEFLQKRFIKIYIPYIIVITVSVLLPYMTQDLNAAKVYLSHVLLFKIFLPVYEESL
                     GPFGLFRQLFSSISYSYQL"
     gene            29973..30416
                     /locus_tag="RD508_001673"
     CDS             29973..30416
                     /locus_tag="RD508_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736276.1"
                     /translation="MEAYEFLGAALRNIFGNLLSACLVAEYLVKRKIVRFNNIFVIMA
                     SIVGIGFAGISKIIGGLMESINDIFAFFGYGAIAILMYQVIPFRKIMPRISRYSYDIY
                     LLHILVFSTIHQIIPNLVLAAFVSIPITLVLSYYYSIMLYRLKLK"
     gene            complement(30571..>30718)
                     /locus_tag="RD508_001674"
     CDS             complement(30571..>30718)
                     /locus_tag="RD508_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HDT7736277.1"
                     /translation="EKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRY
                     SLGY"
BASE COUNT        10004 a         4479 c         6589 g         9646 t
ORIGIN      
        1 tattattaat tcaatgttaa tttttttgtt attttatttt ttgtgtaact tttaaaaaca
       61 cctatgaaaa ttaaggaaat aaaaatgaaa tcgattaatt gttatcttat taatgtttta
      121 tttactttta aatcataaat tgccctagtc aagaaaacag tttgtggtat gattatatag
      181 ggaaaacttg tttacaaata tttctgtgaa tatattagtt taattatgtt ttttaaaata
      241 aaaagctgtc atttttatgt aagtgaatta tatcttaatt tatctatcat caatacttag
      301 gagtgaatct atggaaaagc cattcgtcaa gtcattgact gctgtggcgg taggtgcagg
      361 tgctattgcg atctgtttgt ttggttacca tatcaataat cagcggcaac atcagcaacg
      421 gatcaattat gcagaatctg ccatcaccaa tcaaaaagac accttgactt ctttatcaaa
      481 agaagtagac aagctgtata gtacaaaaga aaaaattttt ctaaaccctg aaataacaga
      541 agaaacaatc acaagtttgt caaataagct atcctatgtc aaactttcag cagatgatta
      601 cgacatcaaa gaatcagaat tgcctaaaga agctgttgca atccaagatg agaagaaagc
      661 aatcgtgaca cagttagata gtgcagaatc aaaactgaag atccagacag ctgtcaacga
      721 tttgtttact aaaaatgtat caaactggca gcaagctgta gacgatgtca tcatcaaaga
      781 aaaggtgaca agtgcagatg tcgctcgtgt acgtgaaaat atgagctttt ttaaagatag
      841 tccttggaaa acggttgtta tgcaatattt aggattcgct gatactcaga tcgcgcaagt
      901 cacgcaacta gatcagttat tcgatacgat gttgaaggat ggtcaagtga ctgccaccgc
      961 tacttacgat caatatttga cggcgctcag tcaaatagag cagatccgga atgaaaaaat
     1021 aagcgcagca tacgcaacaa aagcacaaac tgttgctcag caaatgggct atagcaatat
     1081 aagttattga cagttaaaac gttgattcaa gcaaggttag caaacggagg aaactatggc
     1141 aagacgaaga agaaaatcaa gagggaaaaa aatatttctg attattttag cagttcttat
     1201 cgtattagta ttagcaattg taggagtagg agcaaaatta tatctggatc tctcacattc
     1261 tattgagaaa acttacgaat cagtggaacg aacccaagga gaacgaacga aaccagttga
     1321 tctggacaaa caagaatctt tctctgttct attgatgggg attgatactg gagatttagg
     1381 tcgggtcgat caaggaagat cagatacgat gatggttgcc atagtcagtc ctgaagacaa
     1441 acagacaacg atcgtcagca ttcctcgtga tacgtatgtc gacatcgtag gtcgtgacac
     1501 aaaagacaag atcaaccacg cttacgcatt cggcggagct gccatggcga tggataccgt
     1561 acaaaaatat gtagacatcc caatcgatca ctatgtctct atcaatatga aagggctaaa
     1621 ggaacttgtt gatgcagttg gtggtatcga agtcaataat gacctcactt tctcacaaga
     1681 tggctatgac tttacaatcg gtaaaatcac attgaacggg gatcaggcat tatcttattc
     1741 tcgtatgcgt tatgaagatc caaatggtga ctatggtaga caagagcgtc aaagaaagat
     1801 cgtagaaggt gtagcaaaaa aagtattgag tttaaacggt gtcagcaact atcaatccgt
     1861 tttgaatgct ctagagtcga atatgaaaac agacatgagc tttgatgaaa tgaaaaaaat
     1921 cgctttagat tatcgggagg catttggtac gatcaagcaa gatcagctgc aaggagaagg
     1981 ctttatgcaa gataatatct cctatcaaaa agtcagtgat caagaacttg atcgtgtaaa
     2041 aaaagaatta aaagatcaaa tgaatctaga gaataaatag gaaagtggag aaaaaatgga
     2101 agagacaatc aacttggaag aaatttttga aacattacgc aaacacttgg taacaatcat
     2161 catctcaatg tttgctggct tggccatctc aggaatcgta acatttttca tcttgacacc
     2221 aaaatacagt tcacaagcac aattgatcgt gacactgcca caatcagaca cagcaaatgt
     2281 caatgatgtc aatacgaacc tgcaaatgat caatacgtat aaagatatga tcgtcagtga
     2341 tttagtacta aatgaagtca aagatcgttt agaaacagaa gacaatgtga aaatgactgc
     2401 tggacaaatc aaagatgcga tctccgtcaa tcagtcacaa aattcacaaa tgttctcgat
     2461 ccaggcaata agcacgaatg cagtgactgc tcaacagatc gctaacacaa cttcacaagt
     2521 tttccaagag aacgcaaaag acgtgatgaa tgtcgataaa atctcgatta tttcaggtgc
     2581 agttgccaat acgacacctg tttcgccaaa taataaattg aatctagtga ttggcttagt
     2641 attaggaatg atggtaggcg taggtctggc attcttattc gaattacttg atcggacagt
     2701 gaaagatgaa aaatatgtga cggatgcatt aggattccca atcttaggaa cagttccaga
     2761 aatgtcagcg aaagaattga acgctggtat ccgtaaaaaa ggaacagctc ctgcacgacc
     2821 aaaagctaca aacgataaaa cagccccatc acgcagaagc cgctcaagag tctaggagga
     2881 agaaaaatgg cacgaacaca gaaacaaaaa gcagcacaaa ctcatgcagt cagtttgatc
     2941 acattaacaa acccatcttc accaatcgcc gaacaatatc gtacgatccg gacgaatatc
     3001 cagtttgcct ccgcagctgg tcagcaaatc aaaacgattg tcgtgacttc atcaggtcct
     3061 ggagaaggaa aatccaccac tgcagcaaac attgcagtcg tttttgctaa atccggtcaa
     3121 cgagttctac tagtcgatgc agatttacgt aaacccgtcg tctataagac attccagctg
     3181 aacaatgcca ggggattaag tacagcactt agttcatcag gaagtgtagc agatgtaatc
     3241 caacgaacgc cagtcgagaa cttgtcgatt ttgcctagtg gacctaagcc acccaaccca
     3301 tcagaattgt taagttcgcc aagaatggat cagatcctag acgaagcaag acagttattt
     3361 gacgtggtga tattcgatat gccaccagta gtagccgtaa cagatgcaca gatcatgtct
     3421 tcaaaaacgg atggcacttt attggtcgta cgtgaaaata catcacgtaa agaatcattg
     3481 aataaagcaa aagaactgct agagatggta caagcacgag ttttaggtgt tgtatacaac
     3541 ggagcagaac atagcaaaga tgctggttat tactacggaa attaaggaat aagaagagag
     3601 gagacaagag aaatgatcga tctacattgc catatcctac caggaatcga tgacggggca
     3661 gaaaacttag aagcaagtat tgcaatggct gaaaaagcga ttcagcaagg catcacgcat
     3721 attttatgca caccacacca caataatgga aaatacagca atgaaaaatc acaagtcatt
     3781 tctctagtcg cttcgttaca agccgaatta gagaaaagac agttgccttt gacgttattg
     3841 gaaggacaag aagtacgtat taccggaacg ctcatcgaag acatccaccg agatgaaatt
     3901 ttatttacag atttagatga tacatatctt ctgatcgaat ttccgacact ggaagtgccg
     3961 ttatatgcag aatggctttt ttttgagttg ttagaactag gaaagacacc agtgatcgtc
     4021 catccagaac gcaacgcgca ttttcgagaa gacccaaatc atttgcttcc gttcctagat
     4081 atgggatgtt tggcccaaat tactgcgcca agttatgttg gtgtatttgg caaagacatt
     4141 cagaaaacag ccaaaacaat ggtcaaacat aatctcgtgc agatggctgc ttctgatgcc
     4201 catggggtct ctaagcgtac cttttactta aaagagtgct atgagcagat tgctaaggac
     4261 tttggtaagg aaaaagtagt acagatgaaa caagtcgcaa aggatctgat caacggggat
     4321 gaaatcagtt atccagtcta tgaagaggta aaaaagaaga agtttggttt attttagttc
     4381 tttattcgta gataaaaagg aaatgaggag agagggaaag tatggaaagt gaagatttat
     4441 tatctcgtat tagtgaagta catcctaatc aagtttggtt ggataaagaa aaagttgaaa
     4501 aacgatatat ctatttattt tttaaaagaa tgattgatat tgtaggaagc attattggtt
     4561 tgattttagc ttctcctttg atgttctatg tagcttatcg aatcagaaaa gaagagccag
     4621 gaagtccgat atttttttgc catacacgtg ttggtaaaaa tggaaaaaca ttcaaaatgt
     4681 ataaattccg ttcgatgtgt ttagatgctg aagaaaaatt ggaagaatta cttgatcaaa
     4741 atgaaataga aggtgcaatg ttcaagatga aagaagatcc ccgtgtcact aaaataggta
     4801 aaattatccg tgccaaaagc attgatgaat tgccacagct atggaatgtt ttaaaaggcg
     4861 atatgagtct aattggtcca cggccacctt tggagaggga agtagctgag tacacgagat
     4921 atgatcttca acgcttgtat gtaaaacctg gttgttcagg tttgtggcaa gttagtgata
     4981 gaaataatgt tagtttccat aaaatggttg agttggattt agagtatatt agtcatcgaa
     5041 gtttaatgta cgacttgagg ttgattttaa aaacgtttta tgttattgtc aagcccaatg
     5101 gagcatatta gttagggata gaatgatgga ttgttaataa aaaagattac acatgttcat
     5161 attatcgttt caaaagtaat aactgtaatt atggagggtt tgaatcactt gtagaaaatc
     5221 taaaaaaaga aaggtgaatg gggcaattca gtatcattat tcttatataa aagaaaatat
     5281 tcgaaatttt gggatgatac cactcttaaa tataatgatc taaatgcttt aatattggta
     5341 tatccgatat aggaactgac gagctattta gtatgataca aaagtatatt gatagccatt
     5401 aataaatttt ccaaaaaata atgacagcac accaattttt ataatttagc ttgttgaatc
     5461 ggtatgttca tgggacggtt caaaaaaaga atcgaaaaaa taaacggtaa aattttagtg
     5521 aatcctatgt aataaaattt ggatagatgg aaaaacagca cataaggagg ctgagtttgt
     5581 tgtcatttct gctcctacaa actatggtag tgaatgtgtt attgaattag tgatgtctgt
     5641 tacttcagag acattgggga taattaactt cactatacct gtagggtata caaaaaatgg
     5701 aagaaaaaat attatcaata gattttattt agttcagaat ttttacgtgg aagtaaatta
     5761 ttgatgataa tctttatcca attagaatta ttatcgtagg atgtgatgat gatagccgtg
     5821 aagttgttca agtatttacc aatgtctaca acgcagaaaa ttagtttggg tttttcggat
     5881 tggaaaattt caatgtataa aatcataaat ttgctgtaaa tagacagttt ggggtagtaa
     5941 tagcccaata aattgttcga taaactcatc tttggggtga gaatagctca atcattgaat
     6001 ttcaaacctg cctttggggt gggattagag gtcaatatgt acctacataa tactttttgg
     6061 aaaatgatgg tgttgagaat gtaagtacat ttcaatgtga aattctaata tagccccaaa
     6121 cgaggtcaat aaaaatgacc taaactcgta tttctcccct aaacgaggag gagatagata
     6181 tgaaaattga atgtgccggc gttggagttg gctgctttta gtaggaatga acatggttcg
     6241 atgagaactg tttcagatag agtggtcgat gatcacaggc ctttaagtcg tttacagatg
     6301 atgagacttg taaaaataga gggacgaatg gaaaaagatg attggtatag aagaaaagaa
     6361 aggtgttcag aaagacgtaa caattgatag ggaagagaat cttaggggac atagattcta
     6421 ttggattgga cgcagagcac aagatatctt cttctcggct ctagctttga ttgcattgag
     6481 ccctgtgatg ctaattacag cgctcgccat tgtgattgac gatcccggtg gcagcccgat
     6541 ttttgtgcag gatagagttg gaagaaatgg aaagctgttc aagttttata aattccgatc
     6601 tatgtgtgta gatgctgaag caaaattaga agccttgttg gcacaaaacg agatggatgg
     6661 tccggtcttc aagattaaag atgacccaag aatcacgaga gttggtaaat ttattcgaaa
     6721 gacaagtatc gatgagttac ctcagctctg gaacattctt aaaggtgata tgagtattat
     6781 tggacccaga cctgctttac cgagagaggt ggaacaatac ggtgactacg aaaggcagcg
     6841 gttgttcgta cagcctggtc ttagttgcta ttggcagatt gctccacatc gtaatgaact
     6901 gtcctttgaa gaatgggtgg aacttgatgt gaagtacatc aatgaaagaa gctttatcac
     6961 ggactggaag attatcttct tgactttaca ggctgtatta tttggatatg gtgaatgatt
     7021 atatatagta ttaggagttg aaatatgtga atattatttt attatcgggt ggtagcggta
     7081 ggcggttatg gccgctgtcc aacgatattc gtagcaaaca attcatcaaa ctgtttaagg
     7141 atgaaaatgg cgaatatgaa tctatgattc aaagagttta tcgccagatt acaactgttg
     7201 acccagatgc aaaggtcact attgcaacaa gtaagtctca ggctagtgca atccataatc
     7261 agttgggaga taaggcttcg atttgtgtag aaccttgtcg tagagatact ttccctgcaa
     7321 ttttgttagc tgcagcatat cttcacgatg aacttggcgt aggtgatgat gaaagtgttg
     7381 cggtttgtcc tgttgatcct tatgtagata attcctatta cgaaggcgtt gaagcccttg
     7441 agaagttggt gcagcagaat acggctaatt tgactttgat gggtattgca cctacatatc
     7501 ctagtgaaaa gtacggttat atcatccctg aaagttctaa cgaagtaagt actgttaagg
     7561 agtttaagga aaaacctgac aaagcaacgg cagagaaata tttagctcag aatgctgttt
     7621 ggaatgccgg tgtatttgcg ttcaaacttg gttacctgtt ggaaaaagct cacgcaatgg
     7681 tggattttga agattatcgt gatttgtatt ccaagtatga gactttaacc aagatcagct
     7741 ttgactatgc tgtggtcgaa aaagaaacga gcattcaagt gatgcgttat aacggggatt
     7801 ggaaagatgt cggaacttgg aacatgatgg ctgaagttat ggctgataat attaagggga
     7861 aagctgtaat ggatgatacc tgtgttaata ctcagattgt gaatgagttg aatattccta
     7921 ttcttgctat gggctgcaaa gatatggtaa ttgcagcaag tggcgatgga attctgattt
     7981 ctgataaaga gcgcagtggc tatatgaagc cgtatgttga gaaaatcagt acggaagtaa
     8041 tgtttgcaga aaaatcctgg ggtacatata ccgttatgga cgttcaggaa ggctccatga
     8101 ctgttaaagt ttctatgcag gccggacaga agttgagcta ccactaccac aattctcgcg
     8161 atgaagtttg gactgttgta gcaggacagg gtaaagcgat tgtagatggt atgaagcaga
     8221 ttcttcgtgc gggtgatgtg gtgactattg ccgcaggatg taaacataca atcgaagccg
     8281 tgacaaatct ggatattatc gaagttcaga ttggtgaaac tattagcgtc gctgacaagt
     8341 ataagagttc tttgaactaa aagttcgcga ggtagttatt atggagatac taaaatttca
     8401 acccgtgggt aaagattatc tttggggtgg agaacggttt aagacggaat ttggaaaaaa
     8461 ttgacttaac accattaagc ttatacgtgg gaatgcttag ttcatctaga cgataactac
     8521 gtacggaaat atcaaatatg aaggacagaa tggtaaaacc gagttgtggt atgtattgga
     8581 agctacaccg gggggtgatt tatgcttttg agtacgatgt aacagaagaa atgttacgaa
     8641 atgctgtgat ggacagatca cttgggaaac atttatataa agaagaagta cacaagggag
     8701 atctttttta tgtcagttca tggtattggc gctggagtat tagtggctga aatacaggaa
     8761 agctcaaatg ttacctatcg agtttacgat tatgatcgag tagataagaa tgataataag
     8821 tgagaattgt actttgaaaa agcgattcag gtaatgaata tggaagccac tttgaaattg
     8881 gagaaaagaa ataagctcat tcatttttat cctggtggct ctcgtgaaat actgtgtaga
     8941 tgtaaatact gtgagcccga aagaatccaa gtaaagacgg ggttttcgtt ctcggtaaaa
     9001 gaggaatctt ttcaagttct tttatgtata tcgggggacg gacaagttga gtcggcaaat
     9061 ggtgttatga aactcattag atttgtaaaa aagatattgt atgtttttgc caacgaatat
     9121 tggaagatgt taagtgttga gcgatgcgga cttactgaaa attagatggg gatagaggga
     9181 ggatatctaa tgtcacgaat gagatttatg aacacagaaa ttgacaatct tacaatgggt
     9241 gaagtattgg tagaggttga aaaaatgatt caagatagga gatgcggata tgttgtaact
     9301 ccgaatgtgg atcacattgt tcagttggaa acaggaaaag agttgcaaga tgtttataaa
     9361 aacgcatctt taattttgac ggatggtaaa ccattgattt ggatttcaaa gttttataag
     9421 acaccaataa aagaaaaaat atcgggatcc gatatatttt ctttactgtg caagatggct
     9481 gcagaaaagg gatacacaat gtatttttta ggtgcggcag agggcgttgc ggctaaagcg
     9541 gcagataacc tgatgaaaag atttccggga ttaaatgttg taggaacata ctctcctcct
     9601 tatgggttcg aaaaagacga agatgaaatg tttaaaattg attcccaaat taaacgagca
     9661 aatccagata tgcttattgt gggtttgggt tgccctaaac aggaaaaatt tatgttttat
     9721 aactgtgata gattgggagt acctgtgtct tttggtctag gagctagttt ggactttgag
     9781 gcagggaatg ttaaaagagc accaaaatgg atgtcagatt atggatttga gtggctgttt
     9841 agaattactc aggaccctaa aagaatggca aaacgatatt tggttgatga tttaaaaatc
     9901 tttaaattag cactaaaata tcggaaaaaa taaactatat tcaatgagga caatgaagta
     9961 tgattattac aaaaacacct tttcgcatgt ctttttttgg cggcggaacg gatatggaag
    10021 attattttcg agaaaatggc ggtgcagtgc tttccactac ttttgataag tactgttatg
    10081 tgaatgtgcg tcatttgcct agattttttg attacagcac agagttatca tattctcgta
    10141 ctgagagagt aacaaatatt gaagatatcg agcatcctgc aattcgtaat gcgatgaaaa
    10201 tgctagatat gcatgaaatt cgccttacat atgaagcaga tcttcctgca cgttctggtc
    10261 tgggtacatc tagttctttt gccgtaggta tgttgaatgc tttctatgct ttgaagggca
    10321 agtacgctga caagaagaaa ctcgttgata aagcaattta tcttgaaaga gtcctttgta
    10381 atgaagcagg cggatggcaa gatcagattg cagcagctta tggtggcttt aaccgaatca
    10441 atttcaactc agatggctat gaagtattgc ctattattat tacgcctgag cgtaaaaagc
    10501 agcttaacaa caacttgatg atgttcttta ctggattcac cagattttcc tctgatgttc
    10561 agaaggcaaa taatgtcagc ggcacagagg acaaaagagt aagactgaaa aaaatgtatg
    10621 agcttgtgga tgaagcagaa gcggttctga ctgataagaa cagagatcta gatgatttcg
    10681 gcagactgct tgatctcact tggagattga aaaaggctac cggtggtgcg attagcactg
    10741 gaagtatcga tgaactttat gaaaagggca tggctgctgg tgcattgggc ggtaaacttc
    10801 tcggagcagg tggcggcggt ttcttggttt tttatgttca gcctgaaaaa caaaatgctg
    10861 tgcgttcggc aatgagtaat ttgatgtata ttccgtttga atttgaaaac ggtggaacac
    10921 aggttattca ttacacaccg gaaatgtata ttccaaaata aagaaatcag cgaggataag
    10981 aatatgaaag ttgttattat ggcaggcggt aagggaactc gcatctcatc ggttgcaagc
    11041 gatattccaa agcccatgat taaaattgaa aacaaaccgg tattggagca cgaaatcgaa
    11101 tgtctgagag accagggatt cacagatatt attcttaccg ttagccatct tggcgatatc
    11161 attatgaact attttggcga tggttctgga atttcaccag ttactggtca gccctttgac
    11221 gttaaaattg aatacttttt ggagaaagag ccattaggaa atgccggtgc attgtttcgt
    11281 ttaaaggata atttgaccga agacttcctc ctgctgaatg cagatgcgat gtttgacgtt
    11341 gatttcaacc gatttgtagc atatcaccgt gaaaagggtg gcttggtgac attgtttact
    11401 caccctaaca gtcatccata tgacagcggt ctaatcattg cagataagga tggctctgta
    11461 gacagatggc ttgtaaagga agattcccgt ccaacttatt accgtaacag agtaaatgcg
    11521 ggactccatg tgattagtcc tgctgttctt gatgtcgaga taaacacacc taagattgac
    11581 ttggaccgtc agttattaaa gccgttggca ggaaccggaa aaatgttctg ctatgatagt
    11641 ccagaatacg taaaagacat gggtacccct gatcgttatt atgctgtctg tgaagatttt
    11701 aaggctggaa gagtgaaggg caaaaatctt cagaataagc agaaagctgt tttccttgat
    11761 cgtgatggaa cgattaatca atatgttggc tttctgcgtc atattgatga gttcgaacta
    11821 atcaagggta ctgaagatgc agtgaaaaag atcaatgccg ctggatatct ggctattgta
    11881 ataacgaatc agccagtaat tgcaagaggt gaagtttctt ttgaagaatt ggaagagatc
    11941 cataacaaaa tggagacact tcttggatat aagggcgctt atttggatgc agtttattat
    12001 tgcccgcatc atccacataa gggatatgag gaagagcgcc cagagctaaa attcgattgt
    12061 gaatgcagaa agccaaagcc cggaatgtta attcaggcag ctacggactt caacatagat
    12121 ttgagtcagt cttggatgat tggcgatggc gagaatgata ttaaagcggg ccaagccgcc
    12181 ggctgtaaga ctgcattggt tggcgagagt gagtatggac aggatatgac catagcaacc
    12241 ctgagtgaat ttgcagataa gatctgctaa gggatgtttt atcacgaaag gagagtataa
    12301 acaatgatag acaatagatt acagaaacac attgatttgc tgattaaacg ctatcccact
    12361 cttgaagtaa tcaagcagga tattgttgac ggatacctga ttatggagga atgctattta
    12421 aatgatggca agctgctgat agcaggaaat ggcggatctg ctgctgattc cgagcatatt
    12481 gcgggtgagc tgatgaaaag ctttaagacg cctcgccctg ttagtaggga atttgcagat
    12541 aaattgattg cggttgatcc tgtaaagggt tctgaattag ctaagaatct tgaatatggt
    12601 ttgatggcga ttcctctcgt tgctcatgaa gcgctttcca ctgcgtatat taatgatgtt
    12661 gatggcctag gtgttttcgc acagcagttg tttggatttg gaagacctgg cgatgtattc
    12721 cttggtattt cgacatccgg caatagcaaa aatgtgataa atgcaactgt tgttgctaga
    12781 gctcttggta tgaaagtaat tggcttaact ggagccaaag gtggagaact tgcaagggta
    12841 gcagatgttt gtgttaaagc tcctgaaaca gaaacatata tgattcagga gtaccatttg
    12901 ccaatttacc actgttggtg tctaatgttg gaagataaat tttttgggaa tagataaaat
    12961 atctaagccc atattgaaag gataaaatta tgaatgtact atttataaca actcaatttc
    13021 catatcctct agataatggc ggaaaaattg gtgcgtacaa cggtatcagt gttttatcta
    13081 gagactacga tgtgacggta ttgtctttca ccgaagaacc gcagtatgtt gaagaaggtg
    13141 tcagtttttt tcgagagaaa tttaatagtg taaaatttga aaatcctgtg atacatgatg
    13201 tacacataag aaataatcca atgaaattgg tagaagcttt agcaataggg tattgtctac
    13261 gccaacctta tatagtttca aagttttatg attcaaaaat gctgcagtta atagatgaaa
    13321 aattttctaa caatgcatat tgggatatca tttttattga ctatctgaat atgcaaagtt
    13381 atggtcaata catacgggag aagtataaaa cacaatttgg taagtatatc ttaaaagacc
    13441 acaacataga atatgattta gtcctacagg aagctgaatc aagtcgaggt ttaaaaaaga
    13501 agttgcttca gttagagtat aagcgtactc gaaagtatga agaggccgca gtaaataggg
    13561 ccgattattg ctttagtgtg tgtgatgcaa atacggaagt actgaaaaag attaatgaca
    13621 acagttatac gatgcttcca acttatgaaa tgcttacagg ggtgaaaaaa aatatagaga
    13681 agaacacgat cctatatttg ggtaaccttt cttggaaatc caatatgcaa ggattagttt
    13741 ggtttttaga gtcaatttat ccaaatattc aacaaagaat tccggatgta aaaatcacaa
    13801 ttgtcggtag cgggccagtt ggaacagatt ttagtaaata ttcaggcgtg gattatcgtg
    13861 ggtatgtaaa agatatttca cacatttatg acgatcaagc ggtgctaatt gtacctttgt
    13921 tagaaggtag tggtataaga ataaaaatat tagaagcgtt caataatgaa attgcagttg
    13981 tatctacatt agttgggtgt gatacgattg gcgcaaaaga tggaagtgag ttatttatag
    14041 cagataacga aaaagatttt gcaacggctg tagttagact gcttgaagac atgaatttga
    14101 atgaaaaagt aagaaagaat gcaaaattat tcttaaaaga aaaatactcc ttaacggcta
    14161 gacaagatga gtttagtgcg ataattaaca gctaatatat atataagctt atctgatgat
    14221 gatttatagg aggaaatata tggagatggc tgagagaaag gaaaagaaac ttggaaataa
    14281 gaatatcata ttattttaga aaactcctgt tattttatgt ttgtgtgatt gttgcggcta
    14341 tgagttacca ccttacaggc aattccaatg tagcgtcatt aattgctgta gtaggagtag
    14401 tttatgctat tgtaaaggcg tgtaataacg agtatctggc tatatgggtt atgtttgtat
    14461 taggttctga tatatggggg atagtgccat atattaacat tggtagtggt gtgttgcatt
    14521 ggtcagattt taatgttata gtagcgatat ttctctgctt gagattcatc aaagttaaag
    14581 ctaggagtag atacgggatt gtctatagtg taatgcttat atttattttg attgcatgtg
    14641 tgcaatcgca ttcaatctat ggacaagatg tacatacaac gctcttaaca gctagagaat
    14701 tgctagttgt aatatccttt tggccgatag taaaaatagt atattcagaa agaataacta
    14761 aaaatgaatt cattgattta gtgtgtaaat tcacaagatg gacaatgtgt atatattggt
    14821 ttgaatggat tcttgttaat atgggattca atataacctt tttacagaca ggtgcacgct
    14881 ggggtactag aatctatata gatccgatat ttatcatttt atatttcttt ataaatctat
    14941 atgcggttat atataaaaga gagggctata atagtacaaa taaaagtata tggaattgca
    15001 tttttagttt actgacattt gttataatct cgcaaggcag aagtggtata ttatatgtag
    15061 taataacctc ggttattatg cttttaattt cgcttaaacc atccaagatt attagatttg
    15121 gtatattagg aattgcctta attgcatgtc tagtgtctgt gacccaaatt agagaggtcg
    15181 ttatatcttc gtttgtagag tctcagagca gtgacacagg taatatcgca tatagaattg
    15241 ctgaacaaga ttattttgaa aataaattag aaggtcatga actatttgga gttggtatac
    15301 caaacaatca tgatgccaga gctgtagaat attcaggcaa aacaatagat tttgagtcta
    15361 aaaaatataa tccctattat cttgaggact taggcgcttt tgaaattcgt tatagatttg
    15421 gtataattgc atatgcgtta tatatagttg ctttagctat aagtattata gatgccggat
    15481 ttcgaagaga caaatcggtc gccgcatttg cgggtatggc attcatggtg tttatggcgc
    15541 ttaattttaa tttgctagcg tatattacag caagaccgtt cggatttatg atttctttaa
    15601 ttttgataga aatatcggca ttcaatgatg aattcatata tattgaatag gtaagggaga
    15661 gcacagatga atttagatcg attaaagaaa atagcaaata tgatttcacc aatcataaaa
    15721 gtgataaatg cgccgttagc gtattttagt gggaaatcag attatatgga gaagggaata
    15781 ttgtggccta ctgtaacaac ctactccaat aacagtagaa aagtgattca atatacaact
    15841 ttacctaaaa acgtagacaa catggctcaa atgcaatggg ctggggaaag ttttgaggac
    15901 atatgtatag ttcttcaagg tccagtatta gaagacggtg attttacact aaataccgtt
    15961 aaaatgtata ataaatacta tcctaaagta aaacttgtag tgtctacttg gataggatta
    16021 tctgaagaga cagaatgcaa gttgcgtgaa gctggtgcag atgttgtatt atgcaagaaa
    16081 cctgaaaaaa caggtgcgta caatattaat ctacaactta cttctgcata cgaaggcgta
    16141 aaaatggcgc aaaaactggg gtgtagttat gcgctgaaaa cgcgaactga tcaaagacta
    16201 tatgcaaatg atgtactaaa gtatttccaa acattattga atatttttcc atcttcggac
    16261 tgtaaagtag tgaatcagcg attaatattt acgacttatg gaaaatcatt tagatatctt
    16321 ccgtttaatt tatgtgattt tttggtatac ggagaaacta gtgaattatt aaaattatat
    16381 ggtattcaaa gagataaccg agcatcagac tttgggaaaa ttatttatac tgaggaaaaa
    16441 gagtttaata aaaagatatt tacactacta gaaggaaaac aaggtgtatc tccatatgat
    16501 gtttttccag attttgatgc actatataaa aaatatatgt ttgcagaata ctatattgtg
    16561 tataattatt tcctggaaaa tattgcaagt aatgaatctt atggtgactt aatggatgcc
    16621 tattatagtt atttaaagaa atatgcagtt gttgctgatt cagaaaaatt gttactatat
    16681 tggccgaaat atgttcaata taatgttaag ttcgaaaatg aacttgattt ctatgcgaag
    16741 ttggattcaa aaaaatggat ggatatttat gctaattata caccttttag tcagtgatta
    16801 tatggaaagg atgaggtgaa taatgaaaat cggaatagtg actattgtta atggggcaag
    16861 ttttggtaac agattacaaa attatgcgac tcaaaaagtg ttggaaaata acggctatac
    16921 agttgagaca attaataatt gttttgacaa agaaagtacc ctatccattg ttatcaaaaa
    16981 cgctatttat acattattta agtttatacc gcatttcaaa aagtcaaaaa gtatctggaa
    17041 aagaatgtat acattttatc aatgggacaa gcagtatata gattattctc atcgtaaaat
    17101 tgatgcatct aaaaaaaaca gctttgtgag tataaagaat gattatgact atttcttggt
    17161 tggtagcgat caaatttgga atccaaaata tgcagccaat aagggatttg aacttttatc
    17221 atttgttcca aatgaaaaaa gagtttcatt atcaaccagt ttgggagttc catctatacc
    17281 aagtgattta gaaaaattat atgtgacaga gtggaataag tttaaatcaa tatcggtacg
    17341 tgaaaatcaa gcggcaaaaa taattgagga cttgacaggc acaactgcgg ctgttcacat
    17401 tgacccaact ttaatgttgg agcgttcgga atgggaagcc tttcaaaaaa aaccagacaa
    17461 tattgatgaa aattacatct tgtcgttttt cttaactaat ccgcctaagg atactgttga
    17521 tgtattagat aaggtcgcta aagatttgaa aataggtgtt ctcaccttag atgcgtcttg
    17581 ggaatatttt caagatatta ctccgaatca ttttgtttat ttgatttcac atgcaagaat
    17641 gatttataca gattcattcc actgcacagt tttttcattg ctatttggaa aaccggttgt
    17701 ggtatttgac cgttttgata gtgaaaaaat gaattctagg ttaagtacat tgttaaataa
    17761 agtaaataaa gcacattttt gggtaggaaa aaaagctgat gaagcaatga ttcgtgcaat
    17821 agcatctgaa cctgaatatg acatagataa gctgatggta tcagagaggg aatgtgtaaa
    17881 agcttatctt aaagagtatt tacagtaaaa ttttgaaatg ggatgaaaat atggagcatt
    17941 taagtgattg ttttggtaaa atgaagattg ttacgacttc atgcgcaaga gaatatttta
    18001 aggatgattt ggataaatca gagtattcat gttttgttga ttctcgagca gctatgtttt
    18061 tcgcaatggg acaagcttta gctaaaagaa ggaatgtagt tgtaatgctt gctgatgaat
    18121 tgacatcgtg ttatacggca ctaacagaat gtgcatttca acaagttgat ttaattgtgt
    18181 ttgcttttca gacagtcaga catgaaattg atttagcatc tttgaagaat tgtggttgca
    18241 atctaattaa ctgtagcgcc caagacgata ttgatagagt tgtgtccaac actaaggggt
    18301 taaatcagac aacagtaatt aaaatcaata tgaattgtga gtcggataaa gatcatatat
    18361 gtgagtatat agacctgcca gacatacctg tttttttcca cggtagctta tactcacctg
    18421 caagtaaaaa gaaatatgag cagtatggac aggtatcgaa gtatttaggc tatctcgtgg
    18481 ggggaaaaga tgcaatactc ataatttctc acaatgagtt tttaaacgat atcagtgtat
    18541 ggattaatta ttattctttt ggagaaattc aacccaaaat tattatattt gacagtccga
    18601 atgactatca atataaatgg ctgtgtgact tagaatgcag tgtagctcat tcaaccaacc
    18661 gatttttgtc tgaggattta gccttattgc aaaataacgg aatttccatt gtgttaagag
    18721 gtgataatta tgatatcgtc agttaaaaat gttcaaattt tagtatcttt attaaaacag
    18781 cataatatta aagatatagt tatctcgcca ggtagtagag attttcaatt ggtgcatagt
    18841 gtagaaacag acagtttttt tagaacctat acggttgtag atgagcgcag tgctgccttt
    18901 tttgctaatg gactttctat ggcgattgat aagcccgtgt gtgtatgttg tacttcttca
    18961 actgcctctt caaattatat ggcggcagct aaagatgctt ttgctaatgg catccaactt
    19021 gtacttctta ctgctgatag agattaccgc cgcttatatc agatggaaga tcagatgatt
    19081 gatcaggtag atatgtatgg ggcttatgtg cgttctaacg ttgatattcc tattgttaag
    19141 gattctgatg atgaatggta tgctaccaga aaaataaatg aagcaatatt ggagttaaat
    19201 catggcgtta agggtcccgt gcagattaat tatcaattaa tggatttaag tgcgccgttt
    19261 gttgagacca tgccagagta tcgtaaaatt acaagatatc aagaggatga tttactgtca
    19321 tcagtagaga tttttaaaca gaaactatta tcaaaaaaga gaataatggt tttatgtgga
    19381 cagcaggaag aaaataattt aagtgcctta ttggaagagt tctttattaa atataataca
    19441 attataatca aggataacta ttctaatata cacggtgaac actttattaa gactgttcta
    19501 gtaacagaaa gaatgagtgt aaatgcattt attgattatt gcccagattt ggtaataact
    19561 attggtaaac atgtatggtc ttttgtgaaa tatactctta gagataaaaa gcttaaattt
    19621 gagcattggc ggatatctga ggatggtaag attgttgatc cgttcaacaa gctaacatct
    19681 gtctttcagt gctcagcgga attttttatg gagactgtca ctgctggtgt gaatagcaat
    19741 aataatcttg agtattataa tctatggaag acaagattat caaaagtttg ctatccagag
    19801 ttagtctata gcaattttta tgcaatttca gaactagtaa aaaaaattcc agatagtgca
    19861 ttagttcatt ctagtatttt aaatgcggct agattgtatg actttgtatc tgatgataaa
    19921 gcattactca gttttgctaa tttaggggct gatggtattg atggttgttt accaacattt
    19981 ttaggtcagg cagaagcaga taaaactcga cctgcgtatt taatttcagg agacttgagt
    20041 ttcttttatg ctatgaatag tttatgtggt gacattccag ataatgcaca tattttcctt
    20101 attaacaatc attctggaag tgaattccat acaaattttg gtaagtttta caacggatca
    20161 ttaagtgttg ataagcatat agctgcagga catatttcaa acgcaaagga ttgggcatta
    20221 gaaaataata taaaatacat tactgcggat tctaaggaaa gtctcaaatc ggggttggat
    20281 gtatttatta atacatttga cagtcctgtt ttatttgagg tctttacaga tccggatacg
    20341 gatacgtctg ttctggaatc tttttatagt ataaataagg taatcacacc aaaaatgtat
    20401 tttagaaagg cgttagatat tataaaaaag catttacaca ttaagtagat gtttattgcg
    20461 aggtgaaaca aatatggcaa taaaatctta tattaaacgg ttattgcttt atatccgtca
    20521 tggagatccc aaaataaatt tagatgtgag ttatttatct gaaggtgcaa tgcttgctgg
    20581 taagactgtg ataattacgg gtggtgcaaa aggacttggt tttgcaattg caaaatcatt
    20641 tatagctcaa ggcgcaagcg ttattattac aggaagagac atggattcgt tgaataatgc
    20701 taaatgtcag cttggagata tgtgttctat cagggcgttt gatataactg atgctaaaat
    20761 gtatcgaacg ttttttgaag atgcatacga gacctttgga cgtattgata tactgcttaa
    20821 taatgctggg atctcgttac acgaagatgg atttatgagt gttactgaga aaacttggga
    20881 taagcaaatg gatacaaatt tgaaaggtgt ttatttcttt acacaggaat ttattaagtt
    20941 tgttaaagaa aagaatcaaa tgcaagcaaa tattattatg atgtcctcag aaagaggctt
    21001 gtgtggtgat agtattccgt atggattatc aaaggctgca attaactctt tagttgtagg
    21061 cttgtctaag aaatatattt ctgagggaat tagggttaat ggtattgctc ctggagtaac
    21121 tgcaaccgct atgactggta tttctgaaaa gggtaatttg tataatcctg caacgatcgg
    21181 ttatagatat tttctcccag aagaagttgc tcaagttgct ttgtttttgg caagtagtct
    21241 ttcaaactgt atcagtggtg aaatcatagc ctgtgaccag gggcaatatt taagtcgaaa
    21301 ttgggggtaa taacttggga atattattaa aaaaatataa tagccttagt gagcctgcaa
    21361 aagcatctat ttggtttaca ctttgtaatg tgttgcaaaa aggaattcta tttttgacta
    21421 cacctatttt tacaagaatg ctttcaactg cagaatatgg taagtatacg atttttatat
    21481 cgtggtattc tattatagca attttcacaa cgttgaattt atctgcaggt gtctataata
    21541 aaggactaat taaatacgag aataaatatg cattaacctc gtcattttta ggattatcgt
    21601 catttatttc cctttgtgca ttgatgctat accttccatt tagaacggtt ataaatgggc
    21661 tactggattt atcgacggag tttgtcatat tgattcttat tgaatcaata tttgagccgg
    21721 cttttttgct ttggtcagtt aaggaacgat ttgattacaa gtatcaaaaa ctagtactca
    21781 tcacagttct tatggctgtt ttaaatccag gtctcggtat tatattaatc ttatcatttg
    21841 gggagtatgc tatttggaga gtacgagctt atgtcgtggt aaatgttgta gtggggatgt
    21901 ttattggcat aggaatactg gctaagggta agaaattatt tgataaagag tactggacat
    21961 atgcgctcag atttaatttg ccattaatac cacattattt atcaatgaca ttgctgaatc
    22021 aggttgatcg ccttatgata aatagtatgg ttggagctag cgaggctgcg atttatagta
    22081 tcgcttacac tatatctagt atgatgaata tcataacaac agctataaac ggttctttta
    22141 ttccttttac atacaaagca attaaagatg gcgtgtatga aaaaattaaa tccgttgcta
    22201 atcaactatt agtgttgatt tttgtcttgt gttcgtttac tatgctgttc gggccagaat
    22261 tgatttgggt tgtcggagga gaaaaatata tggatgctgt ttggattatt cctccagttg
    22321 cggcatcagt atttttcatg tttttatatc cgctttttgg caatattgaa ttttactatg
    22381 aaaagacaaa ctacgtaatg tttgcatctt gtgtgggctc tatcgcaaaa attatttcaa
    22441 actatgttag tattccccgt tttggatata tttcggctgg ttacacgaca ttgatttgct
    22501 atatgttgtt ttcctttgcc cactacatgt tttataaaaa aattcttaga gaaaatggta
    22561 taaaagaaga tatgtataat attaaaaata ttatatttct ttctgtctta atgattgtgt
    22621 taactattgg tatgacaata ttatactttt ctacaattct aagatatagt attattattg
    22681 gattagttat tgtggctttt cttaaaagga cgcaaataat gaaaatcctt aaaaatataa
    22741 aaaattaaca agcaaatctt gggaatggaa cggaggcacg gtgaaatgag attattgatt
    22801 ccatctgcta agattgtacc ggaagaactt caccatcttg gaaaacttcc tgcaattatc
    22861 tatccgatta atcaaaaaat tgtatttgat tatttatatg atcaatataa agatgtatgt
    22921 tctgctatcg atattgcctg ttacgaaaag atggataagg tagcaagacg attagataag
    22981 tatattaaat ctaaaacagt aaatattatt cagcttaaag agttagggga tcttggaaga
    23041 actatatatg attctctaat aggatgtgac gagcctgtta ttattaattt tgctgatacc
    23101 attatcaatg ataatatata ttccttggaa tgtgacagct ttttctatgc tgaagactat
    23161 tatagtaata cttggacatt ctttgaagaa aaagacggag atattatttc tgttttagat
    23221 aagaacgagt taaaagaaga tgatggaaag aagcacaaac tgttttctgg tgtatttcaa
    23281 attatggatg cccagtattt tagagagtgt ttgcgtaaag ctttgatgtc aaatgtagta
    23341 aatgtgaata gtttttatca agctttacaa gagtatagca aacgatatga atttctctct
    23401 attaaaacaa ataattggtt tgacattgga catgcagata aatattataa ttccaaattg
    23461 gaagttaagg caagagaatt taaccacatt tcaattgata aagatcgtag catcctgaga
    23521 aaaattagtg aagatgttga aaaatttatc ggagaaatta agtggtatct taagttgcca
    23581 gcacaggtag aatatgtgag acctagaata ttcgaatatt ctacttcgta tattaatcca
    23641 tatgtaagta tggaatacta ttcgtatcat actgttcacg agttatttct ctatagtgac
    23701 ttaacaaaaa aacaatggat agatatcttt aatagaatac gatttgtatg ctcagacttt
    23761 aagagatact ctgtttcagg ggataatatt caaaagtcat tgaaagatat gtatctcgat
    23821 aaaacatttc agagattcaa taagctcaga aaggaccccc ggttcacaga attcttttct
    23881 tctgatattc aaataaatgg agtcagatat aaatctttgg accagataga agctttattg
    23941 agcgtaagtg ttccaagaga attgtttgac attacgcaat ttaatattat tcatggtgac
    24001 ttatgctttg ccaatattat ggtagataac acattttcgt tcattaaagt catagatccg
    24061 cgaggtaagt ttggagattt tgatatttat ggtgattata gatatgaact ggcaaaattg
    24121 tttcatagtg ttgatggaaa atatgacttt ataattaagg acttgtttac aataaaatat
    24181 gatccaaaga aggcaatcat agactatatt gttcaagatc gtaaacgaga ttatgattta
    24241 tatgaagtat tttactctgt cttcaaagat gaaataggtt ctgatttgaa aaaaattgaa
    24301 cttattgagg ctttgctgtt tttaagtatg attcctttgc atggagaaag cttaaaccat
    24361 cagatggcta tgttagcaac tggtttggaa attttaggac gagttgtccc ggatatttat
    24421 tgttaatgct ttgagctatt gtttttctat ttgatcagtg taaagccggg catataaatt
    24481 gcctggctaa aataaaggag atgtcttagt tatatgttta aagattacgc atttgttttt
    24541 gatattgatg gaactttgtg ccccatcaaa aagaaagatg agaaatatga agatttagtt
    24601 ccgtatgcta atatggtgga gaagttgcga tactataagg agaacggagc aaagattaca
    24661 ctgttcacat ctcgcaatat gaattcttat catggtaatt taggtgtgat caatgcaaat
    24721 actgcaaaaa tcttgttggc ttggctagat aagtgggaga ttccgtatga tgaaattctt
    24781 tatggaaagc cttggccagg ccataaaggg ttttatgttg atgatcgcac agttcgtccg
    24841 gatgaatttt tatcgtgtac cctggatcag ctcgatgaga tttgcaaaaa atccaaattg
    24901 aaatctgagt aaaggagact ttataaagtg aataagatga cggttattat tacaatggct
    24961 ggtcttggca gtcgctttcg taaagttggc tacactgtgc ccaaatttat gattgaagca
    25021 aaaggtaaaa ccttatttga ttggtcctta gacagcttgc ttgattataa ttcacatgta
    25081 gaaaagtatg tttttgttgt gcgtaaggaa gatgatgcta ctgtttttat caaagaacat
    25141 tgcagtctgt atggaattga aaatgtcgag gtagttgaaa ttgactatat gactgatgga
    25201 caagccacta catgtatgct tgcaattcct tattgcgcac ctgataatgc aattatggtt
    25261 tataacatag atacatatgt tgagccaggt gagatgaaat acgttgatat ttctggagaa
    25321 ggacatattc cgtgtttcca tgcggacggt gatcattgga gttttgccaa gttgaacgaa
    25381 tatggtgatg tagtagaagt aagagaaaaa gttagaattt ctaacaattg tactttaggt
    25441 gcatattatt tttcttctgc aaaattatat gcatcactct acgaagaata ttatgcagat
    25501 gaaaggcatc tggaaaagaa tgagaaatat attgcgccgc tatataatta tatgatagag
    25561 aagggcatga aggtaaccat tagtatagta gataaatcaa aagttcacgt actcggtact
    25621 ccagaagagc tcgatgtgtt cttaaatgaa tagggaaaat ataatcatag aaaatgttaa
    25681 ttataaagct gcgtgtgtgg gggagtacta ttcgatagat attctaaaaa tactaatggc
    25741 tattttagtt gttgttcgtc atttaggtca aaactattta gctccagatt aagcatttag
    25801 tattggtatt gttgcaggac tgagtacggt tgccgttcct acttttttca tcatcagttc
    25861 ctttttgttg tgtagtggtg aagttacatc cgctaaatta tctaaacaaa tctacagagt
    25921 acttaaaatt tacattattt ggtctatatt atatattcca ttagtattaa agaattgggt
    25981 acagtcagat tttagctgga aaacagatgt attattgtat atcagagatt ttctgtttat
    26041 tggtagttac tatcacctgt ggttcttgcc tgcactggct tttgctctat ggttagtacg
    26101 caaaagccag gtttctaaaa taaagtttct cagtggtttg ttgctatgcg tagtaggttt
    26161 agcatttgaa tcttattggt ttatattatc tgggaatgat tccatcgagt atattagata
    26221 ttgttataaa agcgtgtttg taacaactcg taatggatta tttataggtg taccatgcgt
    26281 cattattggg caacacttag ccttccacaa aaacactata cttaataagg tctttaaata
    26341 ccgtaatttt atcttatgtg ctgttttagc tataggatgc ttattagttg gtgaaagttt
    26401 catcataaat caaatagctt tgcgagaagt caataatttg ttaatatttt ccattccatt
    26461 agcactggta gttgtatcag tatcactgag cctaaagata gtacatttat aaaaataaca
    26521 gtacatctgc gaagaattag tacgttatta ttttgtttac atccgtatat aatagctgct
    26581 ttaaatttta ttttcccaaa attggggatt acaaattcat taatagaaat gacttgtgga
    26641 atgataataa ttttaatttc tacagttttt gtgtatgcgt gtagtgtgaa atttaccttg
    26701 ctgaaaaaat tatattagat tagtaactgg tacatgtaaa tttgttgaaa ttatagcagc
    26761 atagagatag gaattctgtt gagttttatt ttcgctggcc gaggttattc atgttagagt
    26821 gggtacctcc ttttacgaaa ccttcttgat ggtactcatt tagcgcatga tgaaaggaga
    26881 gtttatgaag aaaatcatat cttctatttt ggttaatgtg ttatctgcat tgtatcaaat
    26941 atttgggttt cgattttaat tgcagttttg gctatgtttt tatacttgtt tgcgatggct
    27001 gaggagaaat caggattagg tttgaaaaaa tcttttcttg tctggattcg gtatttcaga
    27061 aaatcaagct catttagaaa aatgtttttg cttgtgtttt ttacaaatat gattcttttt
    27121 agaacactga tggatagata tgtttggcta aatcctttgt ctaatgtgtt tggtagttgg
    27181 tggatttact ctgtgaatga aacgacaggg gagattagat taactacaga atgttttgaa
    27241 aatgttattc tgtttattcc atttataatt ctagtaatgt ggtataaggc ttcagaaaaa
    27301 gattttggaa aaatttatca gagattataa aatttgtttt tttatgttcg tgtcttatag
    27361 agtttttgca gttattttta cacatagaga cattccaatt gtcagattta ttttataata
    27421 ctttgggtgg cggcattagt ggggttatat attatttgag ctgatatatt catcctaacc
    27481 ttaaaaataa atgagcagaa ttttaaaaga ttggagagat tctatggatc ataatgcaaa
    27541 ttattatcat tggcttacaa atgccaatgc agaaattgta gaggaactgc ggtcatattc
    27601 cgagaaggac attgaggact ccttctataa aaatctgtcc tttggtaccg gtggtctgcg
    27661 tggcaccatt ggtgcaggca ctaatcgtat gaacgtacac accgtaggta aggcaagcca
    27721 gggactgtca gactatctga ataagaccta tgaaacccct tctgtcgtcg tgggctatga
    27781 ttcccgaatc aagtccgatg tatttgcaaa ggttgccgcg gacatctttg ctgcaaacgg
    27841 tattcaggtg catctgtggc cggagctgct gcctgtgcct accgtatcct ttgctatccg
    27901 ttatctgaag gcttctgccg gtgttatgat caccgcatcc cataatcctt ccaagtataa
    27961 cggatataag gtctatggcg caggcggctg ccagatcacc accgaggctg ccgctgagat
    28021 tctggctgaa attgaaaagc tggatatttt tgcagatgtg aaaatgggcg gcgacgcttc
    28081 cagaatcgct tctatccagc cagaggttct gactgctttc attgaagaag taaagggcca
    28141 gtcggttctg tttggcgaag aagtggacaa gaatgttgct atcgtgtatt ctcctttgaa
    28201 tggtaccggt ctggtgcctg ttacccgtac tctggcagaa atgggctaca gcaatgtgac
    28261 cgttgtcgaa gagcagcgtc tgccagacgg taatttcccg acctgtcctt atccgaatcc
    28321 ggaaattaat gaagctatgt ctctgggcat ggagtatgcc aagaagtata atgctgatct
    28381 gctgctggct accgaccctg actgcgaccg tgtgggtatc gccgtgaaga atgcagaagg
    28441 ggattatgtc ctgctgtccg gtaacgaaac tggtctgttg cttctggact acatatgctc
    28501 tcagagaatt aagcacggca agatgcccac tgaccctgtg atggtcaaga ccatcgtgac
    28561 tatggatctg ggcgagcgga tcgcttccaa ctatggcgtg cgtactgtcg atgtgttgac
    28621 cggcttcaag ttcatcggcg aacagattgg tatgctggaa aaggcaggca aggtggacag
    28681 ctatattttc ggctttgagg aatcctacgg ctatctatcc ggcagctatg tccgtgacaa
    28741 ggatggtgtc aacgccgctt atctgatctg cgagatgttc tcttactaca agactcaggg
    28801 tatcagtctg tttgataagc tgaacgagat ttatgctaag tatggctact gtttgaacac
    28861 cctgcattcc tttgagtttg agggtgcggc aggttttacc aagatgcaga aaattatggt
    28921 tgaattccat aaaggtcttg atatgattgg aggtaagaag gtcattgaaa ccttggatta
    28981 cagcacggga ctgaatggcc tgccgaagtc tgatgttctc aaatatctgc tggagggcaa
    29041 ctgctctgta gtggttcggc cttccggcac tgagccgaag ctgaagacct atatcagcgt
    29101 tagcgcagaa agcaaggaag ctgccgaagt aatggaagct gttatggctg ctgaactggc
    29161 tgaaatgttt aagtaatact atgaaaaaga tctgagtgtc aatgtccgaa gtagcaacat
    29221 ctatgtttaa taaaaatttc ctgctttacg gttctgttta cataattgag gtaaaggggc
    29281 cgactgtgtg gatcgaaaag gcaaagaagt gttaacagag acacagcagc ctgatgaagc
    29341 accgatcaaa gcagtaaggg agaaataaga gatattagag ttttaataat gtattcagca
    29401 atagagatga aaggagtaga atatgaataa aactattgaa ataataaaat gagggggaaa
    29461 gaaataaacg tgatattatt agttttgaga aggcgttttc aatattcgct attgtattga
    29521 tgtactattt tcagcaatcg tatttgccag caatactgaa caaagcaata tctattggtg
    29581 atacaggagt gcatatattc ttcttttgct caggttttgg gctatatctg tcatatttaa
    29641 aaaagcctat tacattgggt gaatttttac agaaacgatt tatcaagatt tatattccgt
    29701 atattatcgt aattacggta tcagtgttac taccttatat gacacaagat ttaaatgctg
    29761 caaaagtata tttgtctcat gttttgttat ttaaaatttt tctaccagta tatgaggagt
    29821 cactgggtcc ctttggttta tttcgacaat tattcagttc tatttcttat tcataccaat
    29881 tgtaaaacta tagagaaaaa taggaatgaa atgattgctt gttgcaagct gagttattag
    29941 tatctgggct attatgatgt ttcatacagg atatggaagc atacgagttc ttgggagctg
    30001 ctttgcgcaa tatatttggg aatttacttt cggcatgttt ggttgcagag tatttagtga
    30061 aaagaaaaat agtaagattt aataatatat tcgtgattat ggcgtccatt gttggaattg
    30121 gttttgctgg tatatcgaaa attattggtg gactgatgga gtctattaat gatatttttg
    30181 cattcttcgg ttacggtgca attgcaattt taatgtatca agttattcca tttagaaaga
    30241 taatgcctag gatttcaaga tactcatatg atatatatct actccatatt cttgtattta
    30301 gtacgattca tcaaattatc cctaacttgg ttttggcggc atttgtttcc attcctataa
    30361 cgttggtgtt gtcatattat tatagtatta tgttatatag acttaaatta aaatgatagc
    30421 ataattgtcg cctctaccgg gcggttgcca tcctgattaa cagcctccac gcggcggatg
    30481 gtgggcactt aggtagttcg taacctagtg gtagatggtt ggtaaaaagg agataaaact
    30541 aaatgattac acccgtggtg ctagttaatt ttaatatcct aaagaatatc tcaaagttcc
    30601 ttcaaaacgt cgttgtgctc gacttaatag aacactgtaa gccagtaata tgctttcaaa
    30661 tctactctct agccctttaa cagaacgtga gttgaaattt tgacaaccta atttttct
//
LOCUS       DAPBCF010000030        30492 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.030, whole genome shotgun sequence.
ACCESSION   DAPBCF010000030 DAPBCF010000000
VERSION     DAPBCF010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.030"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            38..126
                     /locus_tag="RD508_001675"
     tRNA            38..126
                     /locus_tag="RD508_001675"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:72..74,aa:Ser,seq:gga)
     gene            141..212
                     /locus_tag="RD508_001676"
     tRNA            141..212
                     /locus_tag="RD508_001676"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:174..176,aa:Glu,seq:ttc)
     gene            228..300
                     /locus_tag="RD508_001677"
     tRNA            228..300
                     /locus_tag="RD508_001677"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:261..263,aa:Val,seq:tac)
     gene            310..382
                     /locus_tag="RD508_001678"
     tRNA            310..382
                     /locus_tag="RD508_001678"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:343..345,aa:Asp,seq:gtc)
     gene            418..493
                     /locus_tag="RD508_001679"
     tRNA            418..493
                     /locus_tag="RD508_001679"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:451..453,aa:Phe,seq:gaa)
     gene            495..575
                     /locus_tag="RD508_001680"
     tRNA            495..575
                     /locus_tag="RD508_001680"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:529..531,aa:Tyr,seq:gta)
     gene            582..655
                     /locus_tag="RD508_001681"
     tRNA            582..655
                     /locus_tag="RD508_001681"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:614..616,aa:Trp,seq:cca)
     gene            658..730
                     /locus_tag="RD508_001682"
     tRNA            658..730
                     /locus_tag="RD508_001682"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:691..693,aa:His,seq:gtg)
     gene            742..813
                     /locus_tag="RD508_001683"
     tRNA            742..813
                     /locus_tag="RD508_001683"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Gln,seq:ttg)
     gene            859..929
                     /locus_tag="RD508_001684"
     tRNA            859..929
                     /locus_tag="RD508_001684"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:891..893,aa:Cys,seq:gca)
     gene            950..1034
                     /locus_tag="RD508_001685"
     tRNA            950..1034
                     /locus_tag="RD508_001685"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:984..986,aa:Leu,seq:caa)
     gene            1096..1168
                     /locus_tag="RD508_001686"
     tRNA            1096..1168
                     /locus_tag="RD508_001686"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1129..1131,aa:His,seq:gtg)
     gene            1178..1249
                     /locus_tag="RD508_001687"
     tRNA            1178..1249
                     /locus_tag="RD508_001687"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1210..1212,aa:Gln,seq:ttg)
     gene            1267..1351
                     /locus_tag="RD508_001688"
     tRNA            1267..1351
                     /locus_tag="RD508_001688"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1301..1303,aa:Leu,seq:caa)
     gene            1606..2481
                     /locus_tag="RD508_001689"
     CDS             1606..2481
                     /locus_tag="RD508_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7736278.1"
                     /translation="MKESASCFVLSYSGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAIEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            2585..3349
                     /locus_tag="RD508_001690"
     CDS             2585..3349
                     /locus_tag="RD508_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HDT7736279.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            3336..4778
                     /locus_tag="RD508_001691"
     CDS             3336..4778
                     /locus_tag="RD508_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7736280.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAIFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            4789..6119
                     /locus_tag="RD508_001692"
                     /pseudo
     CDS             4789..6119
                     /locus_tag="RD508_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
     gene            6132..6590
                     /locus_tag="RD508_001693"
     CDS             6132..6590
                     /locus_tag="RD508_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7736281.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            6882..8183
                     /locus_tag="RD508_001694"
     CDS             6882..8183
                     /locus_tag="RD508_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7736282.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEKAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNATLLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPMIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            8210..8470
                     /locus_tag="RD508_001695"
     CDS             8210..8470
                     /locus_tag="RD508_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDT7736283.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(9469..10704)
                     /locus_tag="RD508_001696"
     CDS             complement(9469..10704)
                     /locus_tag="RD508_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDT7736284.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            11271..12099
                     /locus_tag="RD508_001697"
                     /pseudo
     CDS             11271..12099
                     /locus_tag="RD508_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(12372..13142)
                     /locus_tag="RD508_001698"
     CDS             complement(12372..13142)
                     /locus_tag="RD508_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7736285.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            13360..14427
                     /gene="ulaG"
                     /locus_tag="RD508_001699"
     CDS             13360..14427
                     /gene="ulaG"
                     /locus_tag="RD508_001699"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HDT7736286.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADSKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            14445..14906
                     /locus_tag="RD508_001700"
     CDS             14445..14906
                     /locus_tag="RD508_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7736287.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGEDEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            14926..16410
                     /locus_tag="RD508_001701"
     CDS             14926..16410
                     /locus_tag="RD508_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDT7736288.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPEGYFLIVEDYDTYAEKQRV"
     gene            16453..16752
                     /locus_tag="RD508_001702"
     CDS             16453..16752
                     /locus_tag="RD508_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7736289.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKEVTVIGIKNVMSAKEISEKFAETKWYQKNK"
     gene            16767..17405
                     /locus_tag="RD508_001703"
     CDS             16767..17405
                     /locus_tag="RD508_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HDT7736290.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            17410..18270
                     /locus_tag="RD508_001704"
     CDS             17410..18270
                     /locus_tag="RD508_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HDT7736291.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            18260..18970
                     /locus_tag="RD508_001705"
     CDS             18260..18970
                     /locus_tag="RD508_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDT7736292.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            19202..19636
                     /locus_tag="RD508_001706"
     CDS             19202..19636
                     /locus_tag="RD508_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7736293.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(19733..20032)
                     /locus_tag="RD508_001707"
     CDS             complement(19733..20032)
                     /locus_tag="RD508_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736294.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(20301..20495)
                     /locus_tag="RD508_001708"
     CDS             complement(20301..20495)
                     /locus_tag="RD508_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736295.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            complement(20723..21484)
                     /locus_tag="RD508_001709"
     CDS             complement(20723..21484)
                     /locus_tag="RD508_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDT7736296.1"
                     /translation="MHTPEEIMELSIHLGTKKIHKPILAKLILGFIGGAMISLGYLAY
                     VRVSASIPESMASLTSLVGASVFPIGLLVILLGGGELITGNMMAVAIAFMDKKVTFSQ
                     LVKNWSVITFANIIGAIFVAYFFGHFVGLTHSGVYLDQVIHIADHKIAVSWWQALGSG
                     IGCNWFVGLALWLSYGAKDAAGKVLTIWFPVMIFVAIGFQHSVANCFVIPAAIFEGQA
                     TWLEFLSNFIPVYIGNIIGGAIFVSGFYYVSYKHH"
     gene            21804..22049
                     /locus_tag="RD508_001710"
     CDS             21804..22049
                     /locus_tag="RD508_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736297.1"
                     /translation="MSKSKKNITIIGLGLTVYLFTEFVYRHVNLFAEPLFVLYESNSS
                     IVSELANLMIALLFTPALRVITILVCLVLLFFVNKKK"
     gene            complement(22233..22982)
                     /locus_tag="RD508_001711"
     CDS             complement(22233..22982)
                     /locus_tag="RD508_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7736298.1"
                     /translation="MLKLERHQKILDLLNAEQKVIASDLSQRFNVSEDTIRRDLKDLD
                     SQGLLKRVHSGALRVGPPITNFNYRETVASEQKTALAHKALPFLKEESVIIIDGSTTN
                     LALAKEIPQDFRATIITNSPPIAIALAQHPNLEIINIGGTFYKQSMINIGVQAYKQLQ
                     NIRADLYIMGIYNIDLDVGTSVPTMQESDIKREMIRISTEVLGMITNDKFGTISNHIV
                     GPIEDLTYLISEEIPEKVRKEYNKQKIVLID"
     gene            23168..23872
                     /locus_tag="RD508_001712"
     CDS             23168..23872
                     /locus_tag="RD508_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDT7736299.1"
                     /translation="MEKKIILSPSLMCGDLANLEGSIQELESIGMDSLHIDVIDGSFS
                     PSMPLGIETIKRIREITSMNFDVHIMAKDNDNEFFIGEMLKIGVESITFHYETSLHID
                     RYIQLIKNSGTKVGIALNPATPLNVLQYILPEIDRICLMLINPGFATNKSEKQVSYAL
                     KKITDLCQLVNEKELAVDIQVDGRVSLETIPGLLDAGATNLVLGSTSLFLKGNTLAEN
                     QKLLYQAMKQSVRKNQ"
     gene            23912..24469
                     /locus_tag="RD508_001713"
     CDS             23912..24469
                     /locus_tag="RD508_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7736300.1"
                     /translation="MSYKAAKQNIVREITETLDRISSKDVEQLIKKIEKAERVFFVGV
                     GRVLLALEGMAKRLGHLGIQTVVVGQITEPAITDKDLLIVGSGSGESAFPLTIAKKAK
                     EFGSQVAHIGSNPDSTMKEYSDLFIRIPVQTKLALPEEISSIQPMTSLFEQSVLLLGD
                     SIALVMIEEKAIDMSKLWQYHANLE"
     gene            24477..25616
                     /locus_tag="RD508_001714"
     CDS             24477..25616
                     /locus_tag="RD508_001714"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDT7736301.1"
                     /translation="MKAVHFGAGNIGRGLIGQILHQNGFDLCFIDTNPELIHQLNQDK
                     GYTIEIIDEMNRSDFIDHVVALNSLSELEEVITATKNADILTTSVGAINLVKIAPIIA
                     QALSKRFEQKHSINIVANENVINASDVLKKEIYSLLSEKEQENFDEYAYFVNTAIDRQ
                     SLGKVLGGKMISVVEPYYEWIMDRQQLDPTTSFDMKNVNLVDDMEPYIERKLYIVNAA
                     HAAVAYLGALKGYKTIQEAIQNMEIFNLVKQFLMENIEYFVQKYHFSREELTSFVEKT
                     LNRHGNQKLSDEITRVGSSPIRKLGPNDRLIAPIVKLDSYHLPYDAGIKVIAAGYHYR
                     NLADPEAEQLRRMIVNDGLKATIKKISRLEGKLLNEVVAAYESQI"
     gene            25628..26059
                     /locus_tag="RD508_001715"
     CDS             25628..26059
                     /locus_tag="RD508_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7736302.1"
                     /translation="MLKEQLSGNTMFMDAIDSWQEAIRVSARPLIGKGIIEESYVQAM
                     IQNVLDNGNYIILLPLVAMPHARPEFGSKGVGMSFLCLDKPVMFPSEEPVKFFFTFSS
                     DSPKGHLDLMANLGELLSDEKMYQKLFDVKTEKALLDLIKK"
     gene            26073..27518
                     /locus_tag="RD508_001716"
     CDS             26073..27518
                     /locus_tag="RD508_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HDT7736303.1"
                     /translation="MEVANKKKRVSMRAKVQAIGGFLTNMVLPNIGAFIAWGIVTALF
                     IPTGWFPNESLNELVSPTVSYLLPLLLAYTGGRMVGGTRGAVLGTIGTIGLIIGADIP
                     MFMGAMIMGPLGGWMMKKTDDFLDGKVPAGFEMVVNNFSIGIIGFILMCLSYLVVGPI
                     IQSANQFVTSAIEALVSTGFLPILSLINEPAKVLFLNNVIDQGVYYPLGMQQTLEAGR
                     SIYFMVASNPGPGLGLLLAYSLFGKKAAKQTAPGAIIIHFFGGIHEIYFPYVLMKPLT
                     ILSMIAGGMTGIITFELFDAGLVAGPSPGSIFSYLALTPRGNFLGVMAGVVTATLVSF
                     FVTSVILKADKSTDEDRNFELSVQKSKTMKSEGRKLLKEENAREICTEKKEMNKISFA
                     CDAGMGSSAMGATIFKKKLQKAGITDVEIKNYRIEEVPEDSDLVIVHQDLEERTRKAH
                     PNMKIVTLKNYLQDPVINGLAEEIIGLKTED"
     gene            27804..29429
                     /locus_tag="RD508_001717"
     CDS             27804..29429
                     /locus_tag="RD508_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDT7736304.1"
                     /translation="MKKIYSKEIDCFRGIAVLAVIFYHLPNSLLPGGLQGVTIFFVVS
                     GFLMAKNTIRDEKNRQFSFLHFYYKRIKRIYPFLLFSLVVFIFILGISNIRLIGNIRS
                     ELPSLIFGYNNWWQLNQGVSYFDSYFNASLFKHYWSLSVELQFYLIWPFLFIVIKRMR
                     RKQVFYLIYTLIFVSILFSLFLPSTKAYYHTIAKLFPFLLGVWGYFNRITIGRFFEQN
                     TFSKIWLLLLASLCLILFPIFPYTLNELLISICFALLLASVDDMNIAKKTKIASTKLS
                     FVGKISYELYLVHFPVLIALTNLFKHHHWKYLDIAGLFTVFLCTLLMITCFRKGVQKM
                     RSPKIWTAMALMIIGVSVLVLRAPASRLTADQNQLQSLLKENSSKANAGENLLSQEKK
                     ILFIGDSVMLGAYQELKETFKKEALVDAKESRQITALPEILKEHKDLVSYQQIVIGLG
                     TNGVITDEAIEQTMSLLKDKKVYWVNIKAPTGWQDTINATLATLPNQYSNITMIDWYS
                     ESKNHPEFFYDDETHLNESGRTAYAKYIASVIQ"
     gene            30061..30414
                     /locus_tag="RD508_001718"
     CDS             30061..30414
                     /locus_tag="RD508_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736305.1"
                     /translation="MNSFKKKFVSRFLNMKNFFEKKGDYDAYNYVLNLEKQTYYTLRK
                     NDDNDFWTMLPKMLSIDSKLSLLEEFINLDIEEFCGGKELINMVESDYHTYYKESCGY
                     KVDEQCPQSIIFYIE"
BASE COUNT         9923 a         4721 c         6226 g         9622 t
ORIGIN      
        1 ctcattttga gaaagagtat tgagcttctt tcactctgga gagttgtccg agaggccgaa
       61 ggagcatgat tggaaatcat gtagatggtg caaactgtct caagggttcg aatcccttac
      121 tctccgtagc aaatttacct ggcccgttgg tcaagcggtt aagacaccgc cctttcacgg
      181 cggtaacacg ggttcgaatc ccgtacgggt cattttaatt gaatgttgga ggtttagctc
      241 agctgggaga gcatctgcct tacaagcaga gggtcagcgg ttcgatcccg ttaacctcca
      301 taatgaactg gttccgtggt gtaggggtta acatgcctgc ctgtcacgca ggagatcgcg
      361 ggttcgattc ccgtcggaac cgtcgttctt gttattcaat taataatttt aaaatatggc
      421 gcggtagctc agttggtaga gcaacggatt gaagctccgt gtgtcggcag ttcgattctg
      481 tcccgcgcca ccatggagga gtagcgaagt ggctaaacgc gacggactgt aaatccgttc
      541 cttagggttc agtggttcga atccactctc ctccatttta taggggcata gtttaaaggt
      601 agaacagcgg tctccaaaac cgttagtgtg ggttcaattc ctgctgcccc tgccatggcg
      661 aatgtggcga agtggttaac gcaccggatt gtggctccgg cattcgtggg ttcgattccc
      721 atcattcgcc ctttttattc ttggggtata gccaagcggt aaggcaaggg actttgactc
      781 cctcatgcgt tggttcgaat ccagctaccc cagtttctat aatttattct ttattttgta
      841 gattgataat agtataatgg cggtatagcc aagtggtaag gcagaggtct gcaaaacctt
      901 catcaccggt tcaaatccgg ttaccgcctt agtactaata aatcaacttg ccggcgtggc
      961 ggaattggca gacgcgctgg actcaaaatc cagtgcccgt tgagggcgtg ccggttcgac
     1021 cccggccgcc ggtattgact aagatgtctt catcttagtt ttttattgag aaattaaata
     1081 acatctttta tgatggcgaa tgtggcgaag tggttaacgc accggattgt ggctccggca
     1141 ttcgtgggtt cgattcccat cattcgccct ttattcttgg ggtatagcca agcggtaagg
     1201 caagggactt tgactccctc atgcgttggt tcgaatccag ctaccccagt tattattttt
     1261 aaatttgccg gcgtggcgga attggcagac gcgctggact caaaatccag tgtccgttga
     1321 ggacgtgccg gttcgacccc ggccgccggt ataattatca atatagcaac tttcttatag
     1381 agagttgcta tatttttttt gtttttatgt aattacctcc aaatcaattc gatacaagta
     1441 ttatcataaa acgagtaaaa aagatattga taacgctttt attatgtgtt aaactatttt
     1501 tgtaaattat gtagggtgct actattcaat taggcacgac ctaagaaagg gttctttctt
     1561 aggtcgtttt ttgtctttaa aaattgtttg gagacaaaaa tatgtatgaa ggagtctgca
     1621 agttgttttg ttttatcata tagtggaggt gaattaacgg tgtatgtgat gaaaaagctg
     1681 aatcataatg ctgtattgat cgatgacgat ggaatagaaa aaattgcgat ggggaaaggg
     1741 attggctttt ctgctaaagt gagtaagcca tttgatgttg aggatgctga caaattattt
     1801 gtattagatt ctaaagaaaa gatcaaacga ttcagtgaga tagtctcgca gattccaatc
     1861 gaatttatgg attttgcgga agaagtgatt gaactgataa cagctaggat ctcctctcca
     1921 ttagattcaa atatctatat tacattgaca gatcatattt attttgctat tcaacgaaaa
     1981 agagaagata gagatgtcac agcaattatg ttgccagaaa tgagattcct ttatccaaat
     2041 gaatatgata tagcaataga agtggtcgag cgaatcaatc atcgatatca aaccgagtta
     2101 gggtcaaatg aagtaggatt catcactatg catatcatta atgctgagct aggagagcct
     2161 aatagtttaa agagcttaaa aatagtagaa atgacgacca cgattttgtc ccatctagaa
     2221 aaatcctatt caaacgttta tgataaagaa tcactgactt atcatcgctt aatggttcat
     2281 atcaaattcc tggttaaacg cttgatttat caggaagaaa cgccagtaga aaatattggt
     2341 ttttttactg aaacatttaa acatagcaaa gcgtattgta cagcactaaa gattaaagat
     2401 atcatcgaac agcaatttca acttgccatt caagaaaatg aaatcatcta tttggcaatt
     2461 catctagcac gaatctatta aaataagggc gtaactatct ataggcgcaa ccaaatgaca
     2521 catagtaaat ggactatgat tatttggttg cgcctatttt agtagaaaaa agaaggagaa
     2581 tgaaatggga aaagtgattt ttaattcgga tgattttggc tatagccatg gtgtgaatta
     2641 tgggattatg gatgcttatc agcgaggaat tttgacatca actacattga tggcaaatat
     2701 gccgggtttc gagcacgctg tgaaactaag aaaggaaatg cctaggctag gtgtaggagt
     2761 ccatttaaca ttgacgtgtg gcaaaccact tctcaaaact gtcgatactc ttatcgaaag
     2821 cggagagttc agatccttat cttattatca gcatccattt aacattgaca aagatcaact
     2881 gtatcaggaa tggaatgctc agattcaaaa aatttatcat gcggggatca taccaactca
     2941 tttagacagt catcatcata ctcatacttt ggatgaaaac caggaggtag ttgttacatt
     3001 agcaaaaaaa tatgatttgc cggttcggag caactttgaa cgaaaagatg aagttcgtca
     3061 tgtcgattat tttgagcctt gtttcgatgt cgtaggagaa actgatgaaa aaaaacgaca
     3121 aatcaatacg agtgtggaag aatatttggc aagtttactc atgatattga gagaagataa
     3181 aacgatcgaa gtcatgtgtc acgcagcgta tttggatcag gaattgttaa atggttcaag
     3241 ttttgtgtat cctcgtactc accaagtcga atttttaatt cattcagcat ttgctcaaaa
     3301 agtgaaaaat gatcctttga ttgagttagt aacatatgag gatatttaat agaggaggaa
     3361 taaaaatgaa tgttaaatca aatgtgcaga agcttggaag agcgatgcta cttccagttg
     3421 cagcgatgcc attagcggga ttgatcatgc gtttatcagc tgatgatatg ctgaacatcc
     3481 cagtaattgg tgcagctgga aatgccgttt ttggaaactt ggatatctta tttgctatag
     3541 gagttgcaat cggttttgtc aaaaataagg acaaaggaat acctgcactt actggttttt
     3601 tagcgattgc taccttgaaa aaaggcttag aaatcatgga cccagaagtg aatatgggga
     3661 tttttggtgg aattatttcc ggtttagtag cggcatggac gtataatcgc tttaaagaac
     3721 aaaaattacc agtagttttt tcttattttg cgggcgaaaa attcccattg actatggtga
     3781 tgattctaca aacaatcgca gctatttttt tgggctttat ctggccgctc atccaaattg
     3841 ggattgataa ttttgcaaaa ctgctcgttg atatgggggc attaggtgtg gggatattta
     3901 tgtttttgaa tcgtttgctg atcccctttg gactgcacca tgtgttgaat acgtatattt
     3961 attacgattt aggaagctat acatctccta gcaaggaagt tttcagagga gagatgacac
     4021 gctttatcaa cggagatcct caggctggac tgtttttatc aggttttttt gtagtaatga
     4081 tgtttggtat accagctata tgtctagcta tctataaagc agcttataaa gaaaataaag
     4141 agatggtcaa aggaatcatg ggaagcggtg caggaacttc atttattgca aatatcactg
     4201 agcctgttga atttagtttc atgtttcttt ctcctatgtt gtacgtgatc catgcacttt
     4261 ttgccggttt agcagggatt gtctgttact tattcaatat acgaattggt tttacattcg
     4321 gagcatgtat tgttgattat ctcatcaatt ttcgaatcgc taccaatgct attttgattc
     4381 ttccaatcgg aattttcttt tttgccttgt attacgttac tttttattat ttgatcaata
     4441 agagaaacat tcagacatta ggacgtgaag ctaaggcaga gtttggcaat gaagtaacct
     4501 tagaagaaac agagttaggg ttagcaagta aaaattatga atatatggca acaaaaatgc
     4561 tacaagcgtt tggaggaaaa gccaatatcc tggatgtcta tagttgtaat acacgcctac
     4621 gggtagaggt agtggatccc accatggtcg aggaacagcg aatcaagcaa ttagggataa
     4681 gcgggatcat taaaccaact gaaaaaaatt atcaaattat catcggctta gaagtgactt
     4741 atgttatggc agaattcaat aaattattag aagaatagaa aggaaaagat gatgatgaaa
     4801 aaacagatta tcactatagc tggaggcggg agtacgtata caccaggaat cgttcaagcc
     4861 attttgaaca atgaaaaacg gttgccatta tctgaaatac gtttatatga tattgatgaa
     4921 gaaagaaata tggatatgta cttgattgtt aaatttatgc tgaaaaaaaa ggtttttcaa
     4981 atattcgcat tcgtgcaacg gatgatccaa agcttgcttt tacaggatgc gattttgttt
     5041 tctcacaaat tcgtgttgga ggattggaga tgcgagaaaa ggacgaaaag attccactta
     5101 aacatggatt agtaggacag gaaacgtgtg gactcggagg atttgcttat gggatgcgct
     5161 caatcaaagg tttattggaa attgtcgatc atatacaaga ctatgccccc aaagcatgga
     5221 ttttgaatta tacaaatcca gagtcgatcg tttctgaagc tgttcgtcgt aaatatccga
     5281 atgtaaaaat gattaatgcc tgtgatatga ctatttcaat tgaagaaacg attgcagtga
     5341 attacggtta tgatcgtaag aattggatcg ttacgtatta tggtttaaac cactttggct
     5401 ggtatacatc gatttatgat aaagaattgc aacgagaaat tatgccagag attattgaaa
     5461 aactaataac aaaagaaatg caagtcgccg attttaatat aggagacaaa acttggcaaa
     5521 aaacctttca aatgatgtca gtcatcacga aaaattttcc aagtaatatc ccgaataatt
     5581 acttagagta ttacttatat cctgatatgg tcgttgagca tactgacaaa gagtatacac
     5641 gtgctaatat ggtcatggat ggacgagaga aaaataccaa agaaatggct gataaaatac
     5701 gccgcggtat tgtggaagaa gtattgaact ttaattttgg ggagcatgga caatatatcg
     5761 tcgatatagc tatttccttg ttgaatgatg atcgtcgtcg ctttatgcta atcgttccta
     5821 atcaaggggc gattccgaat ctacggtcag atgcagttgt tgaaataccg gcatatgttg
     5881 gtgcaactgg tgtggagaca attacactaa gaaaaccaat cagtgatttt cataaaggat
     5941 tgatggaggc acaagttgca gcagagaagt tactagtaga tgcttacttt gaaggttctt
     6001 atcaaaaagc tttacaagca tttacattga atcaaaccgt accaaatgcc agagtcgcaa
     6061 aaaaaatact agatgaaatg atcaaagtaa acaaaaaata ttggccagca ttaaagtaga
     6121 ggtgataaaa agtgcatttc tttaaaacaa gaaacattct aaaagctgta gctagtggtc
     6181 aaattattcc attaacagca gtaaaagacg aggtcttttc ttcaaaaatg ataggagttg
     6241 gatacgctat aacgaatcat gatggatata tccatgcgcc agttaaagga ataatcgata
     6301 atatatttcc tacccgacat gccataacga tcgaaagtga atctggcaga aaaatactga
     6361 tccatatggg tttagataca gttgaactcg aaggaagtcc gtttcagata cgggttgaaa
     6421 gtaaccagga ggtaaaagaa gggacactgt tagctattat agatttgaag aagttggagc
     6481 aagcacaaaa agatacggtg atcattgtag tttctccagg catttttgaa ggaaatttat
     6541 taaaacaaaa ccaagaagta aagattaaag atagttgttt tgaattttag tgtacgatga
     6601 aaaaagttaa atagggtgat atttatgggt gaatttacaa aatttttttg aaatgataag
     6661 tttcaatcac tagatttaat cattttgatt tttgttaatt atcgaatttt tttgttgctc
     6721 ctatgattta gaaaacttat tttcaggatt cttaaaaata aatttgatta tttaagagaa
     6781 tatattgaaa taaaatttct taattatata attagttatg aacattcttt gcgttgtcat
     6841 gcaatgaatg gttcatattt tattgaaaag gagtggtttt agtggaaaag ctgatgaaat
     6901 gggtcgaaga gaaacttgtc ccaccaatgg caaaaattgg tacacagcgt catttattag
     6961 caattcgtaa tggggttgtt tcaacattgt cattgatttt gattgggaca ttttttatgg
     7021 tctttatcaa tttaccgttt cctggatgga atgaatttat tgccccttat tcggcaacga
     7081 ttgttttacc ttttaggatg acgatgggat tgatggctat ttatgcaact tttgttatgg
     7141 gttcggatct agctaaatca tatggattag atagtgtgac aggtggtata ttatctttag
     7201 gaacgttctt tatgttacaa gttcctgtaa acgttttaac tcctgaaaag gcacctcttg
     7261 gctgggtctt acctatgagt tctttgggag catctgggat gtttgcgggg atcttatcta
     7321 tgatttttgc agtggaagta tatcgtttct ttaaaaatcg aaatattact atcaaaatgc
     7381 cagaacaagt gccacctgct gttgcccgta gttttgaggc attgattcca ggtgcagtca
     7441 ttttaacaat tacttggctg attcgaagcg tcgcgggctt tgatgtaaac gctaccttat
     7501 tatcgttatt cgagccttta accaatattt tagggaataa tttgcttggt gttttactac
     7561 caatgttttt gatccatttg ttgtggtcat ttggtatcca tggcatgagt attgtagggg
     7621 ctgttgttcg tccaatgtgg ctgatcatgt tggatgagaa tgcaaaggca ttggcagatg
     7681 gtacagctgc cacccaatta ccctatatcg ctcctgaaca gttttatcaa tggacggtaa
     7741 caattggtgg tgcaggagca acgatcgtgg tatctgtttt gtttatattc ttctgtaaat
     7801 caaaattctt gaaagaggtt ggtcgttttt ctattattcc tggtatcttc aatatcaatg
     7861 agcccatgat ttttggagct cctatgatgt tgaatcctta catgttcatc ccgttcaact
     7921 tagttccttt agttttgact attatcagtt attttgcagt caaattagaa atggtcaata
     7981 gatttactgt tttgccaact tggacattac cagctccaat cggcggttat ctttcagcag
     8041 gaaatgactg gcgtgttgtt atcttgatca tgatcaacac attgatagca tttattatct
     8101 attatccatt tgtaaaagct tatgataaaa agatgctgtc agatgaacaa agtcgtggag
     8161 aaaacgaagt ccaaactgtc taagtttggt ttttagaagg tgggaaacaa tgtattggct
     8221 gattttattt tttgttttta tctttttatt aacggctagt caccttatat tgaatatgct
     8281 agctacatat catattcaaa tcaatcgatg gatttgggca ctggcatcat ttttgatcgt
     8341 gattcttcca aagatcattg taccgcatat gaatgttttg ttttcatggg ggacatatgt
     8401 actttgtgga atttttgcta tcaattttat gatcgagcag catagatggt ttgtcacatc
     8461 gaagctttaa atgttctaaa agtggttgtg acagaagtgg ttagcttcaa gaaataagaa
     8521 gaaatttacg aaaattgctt cttaaatttt tgtgaaatgt tggcttattt ttcgtttggt
     8581 tgaacttatt accgcagatg caagcttttg accaccgttt attcggaata tgggactgtg
     8641 acaaggcttt tgtcacagcc cttttttaca taaagattat tattgtttta actgttttgg
     8701 cagaaagaag gaggcaaaaa tgaaaatttt atcagcaatg gattaagaat tagtcgatct
     8761 actaccaaag tgatcaaggc aaatatagat ttgggagctt acaaccatat agtaggggct
     8821 gcagtatggt gtatgaatgg taatatgtat gatgagagtg tttattcaaa tcatgaaacg
     8881 tgtatagaaa taattgcgct gggaatagca atcagtcatg gtgaacgtga cttttagttt
     8941 atcgttgctg acgacataga acattctgac atgatctact cagcatgtgg ggattgctgg
     9001 cagtttatat aggagtatgc atcggattgc gagatcattg tctcaacaga agagggaggt
     9061 tgattatcaa agataaagtg gtaaatccta catttgattt agtaattgtt gaagggacta
     9121 gcagcacaaa tctctacaaa gcgatgcttc tagatctata tgacacattt taagaaaatg
     9181 tatttgccta attattatgg tctttctttt gaagaaacgt tgagatgatc caaccagaga
     9241 aaggtgtcaa agaatttgac taagaataaa tggcagacgc tacctatgct catttggatt
     9301 gcgtcagatc ttttatttta aggatgattt tgtgtttttt agacaccgta atttaagtaa
     9361 ctctaacttt tcaatccact atttactttt tttgtatttt cactgtctgg gtctcgaata
     9421 gcgaaattac tgatgagtct ctattaaaaa agctttttct acttgaaact atattgggtg
     9481 gttgctcagg aaggtttcga tttcttgaat tgcttgttgt ggaccattta ttggaaaaac
     9541 ggcttgcagc gtgcgtgcct gctgacgaat cttgggtgaa gaaacttcgc gcagagcaat
     9601 ctgcagtttt ctttcagtca ctggttttgt gagggcgatt gcgtttccgt attttacaca
     9661 atagtcaata ttacagcttt gctcaaattg catccccaca ccgataaacg gtttgccgga
     9721 ttcacaggca gtttggacgg tcccttcccc gccgtggata aaagaaaaat caatgaattc
     9781 atgcaaaaga tgactagaca gatattctgt tattaaaaga tcttctgagt cagattgaat
     9841 gtcatcaagc agatagtcaa taggtgcaat aaccgctaga tccggttgtt tttgtaagaa
     9901 gaacaaaatt ttgcgtaaca tacgcggatt gcctgaacta cccattgcga aatagataat
     9961 acgttttctt tcttgttgct ttcgctgtat aaaagttagc acttcttcag gcaaggaagt
    10021 actgagctta gcaaaaattg gaccaacgat tcgataattt tccggcagct gttcttcttc
    10081 caaaaatagt ttaggcgttg tgatgagatt tagatcagca tccatcattt gtaaacttgt
    10141 ttttggtaaa ggaagcattt ctttttgtgc agcgtgtttg aaggcattgg ggatccatcg
    10201 ggtatttact atacgctttt ttgtccagtg ccaaagggga ttgcttaaag ggccgaagaa
    10261 acgtaactcg tggggcatca gcgcatgctc tgattgaaaa aaaggttcac tcaaagcata
    10321 gggtttaaca tatactaaag gaatcttttt attgcgggcc gataaaaaaa ttgtcacatt
    10381 cgaacctgtc acaatcagtc gaggctcaaa cttagcaatc agactctgtt cactagtgat
    10441 acgagaggca accatttctt tggtaaaagg gtttttaagt gtacgcaact ggtcaaattt
    10501 tatgatttgt tcttcttgtt ttttcgtaag gatcggcgct agtaaatgat actcaaagcc
    10561 actttctgtg atcaaaggag caaaagtttt agaaaagcca aagaatacac agtaataacg
    10621 gtctttcata gctttggcaa cctcaatcat tcgtgttgtc tcagctaaat tgaatactgc
    10681 aggagcaaaa agaattgtct tcatgaaatc ctccttattg gaatgagtct atcccttcgt
    10741 ttcttactag tatactaaaa aacacagcgt tcgagtagcc tatgtatatt ttgaatatta
    10801 aactgtctct cgctgttttc acaacttcta aatttaaatt ttgtaatcaa gttgaaactc
    10861 caattttcaa aaaaacacgc aacaattttt tgatcgattt atatgttgtg ccagataaat
    10921 acgagaagtt gtgtcattaa aaataaacat gagaacataa aaaataaaat aattatatta
    10981 attgataggt gtgctgtcgt cattatacac acgtaagaaa gaaatagtta tgtttaaaaa
    11041 tattcttaga ctttctcgcc atgacaattt tcactatgtg ttataactgt aaacgataat
    11101 tattcagata acacaaaaag aaatcaagga gcagatacgc cagttgttta atttgaatat
    11161 tattttaaaa ttaaaatttt tattctgttc taaacatttt tggttgttta gaactttttt
    11221 ttgtgtatga tataaaggag aaataatttt ttaaagggaa ggaaattgtt ttgattaaag
    11281 tagatggagc attactaaaa gaataccgaa agaaaaaggg gttaacacaa gtacaattag
    11341 cagaaggcat ttgtgaacaa gcaactgtca gcaatatcga aaacaagaat atgtcgccag
    11401 gcatcaatat cttaagtgcg ctttgcaaaa agctgaatgt cgagatctcc gatatattag
    11461 tagaaacaga agaagacaaa atcaggaaaa aaataaatga gattcaatca ttgaattctg
    11521 tatcaaaata ccaagaatct tataaaattt tacaaacgat cgatcaggaa aaagtaagta
    11581 attctgatct tttaaatcaa attttatttt atcaaggact gcttgatcat ctttatgcga
    11641 aaaaaaccag atgcagcatt attttatttt aatcaagtgt tggaacaaac gaccgaaaca
    11701 gatatccatc acttacaagc agctgcaaac gtggcaatga tctacttgtc aaaaggagaa
    11761 ttagattttg cgaaagttta tgtggagcgt acacttaaaa tattgagtga gactgatttt
    11821 gataatctga tggtctgcat tgtatattat gatatcgcca cctattaccg taaaatcgag
    11881 gattatgata aagcaatcca attatgtgag aagggtattg agtataataa gaaacataaa
    11941 tcgacttatg cattggaata cttgctttat gaaattgctt cttgccataa gcaattagga
    12001 gaagatgatt atttagaaag atatatggac gcaaaaaaaa tagcgcgttt caacggaaat
    12061 gattacgcgg taaaggtgat tgaaaacgac ctgaaataaa gtggttgtga aatcagtgtt
    12121 ctgatttgaa taccgtttat tcgaaaaaag gaggtgtgac ttttgtcata cctccttttt
    12181 tcgatattgt ttgattccta tttaggcaac atataacggt tataaaagaa gcaatagatt
    12241 atgatggtat cgattggatg gacacatctt gggattcctt tatcaatttg agcgtagcgt
    12301 gtttttcatt tatcgataaa tttgttattc atttttttga taatcctatt tacatattta
    12361 cgtcctggtt cttaaaatga atctacttga atggttttta tccccgtatt tctgatctcc
    12421 tctaatactt tttcagaaca aaatttatca gtgatcaaat aatcaaagac tgaaatatca
    12481 gcaatcttga actttgatgt cagtccgatt tttcgatgat cagcgactaa aatcttacat
    12541 ttgattgtct tgttgaccat catttcgttg atcgttgatt catttaatat ctttgttgtg
    12601 accccatgta ctacatcgac tccgctacag ccaatgatac aaatgtctgc attgactgaa
    12661 gaaatcgtat ttaatgcgat gtcgcccact agtgcttctt ttggaaagcg catctctcca
    12721 ccagttaaaa tataactaca attatctttg tgcggagagt aattgatttt cacgttgttt
    12781 gtaatgactg tcaaatggtt agattgaaga aaatccagtg ttttcaacgc agtcgagcta
    12841 gaattgataa acagcgtatc ataatcgtta atgtatttac tagcttctct ggcaatcgct
    12901 tgtttaatcc tttcaggacc agattgatca aaatcagtct ggtttttgta attataagaa
    12961 caataaccgt aattgcgtat gatctcgttt ttttcttcta ataaatttaa atctcttcgt
    13021 atcgtactaa tagatacatc aagggattca gctaattcga aagttgatag ttgttcagtc
    13081 tgctgaagca gttccaaaat ttctttttga cgtttttcaa tattgacaag tgagtttttc
    13141 atgacttttg cctcctgagg gacatcttga tccatggatt tatttgacta gttgttcatt
    13201 taaacattca tatctgtctt tattatactg aaacaatcat tgattactga aagaaaatca
    13261 tataaaaaac aaacggtcat ataaaagggt ttccatggat gctgatacac attaatattt
    13321 acttgtaagt tggaacaacg atatgggggg agcaagcaaa tgagtaaaac tgtcaatgaa
    13381 gtaacaaaag aaaagtggtt agtagaaaca tttcctgagt ggggcacata cttgaatgaa
    13441 gaaatcgaaa cagaagtagt ggatcctgga acttttgcta tgtggtggct gggctgtacg
    13501 ggaatttggc tgaaaagtca tgaaggaacg aatattttat gtgatctatg gtgtgggacg
    13561 ggaaaacgta gtcatgggaa tggcatgatg aaaaaaggcc atcagatgat gcgtatgagt
    13621 ggcgttcaaa atatgcagcc taatttacgt actcagcctt tcgtaatcga tccttttgcg
    13681 ataaaaaatg tagacgcttt aatcgttaca catatccatt ccgatcatct agatatccat
    13741 acagccgcag cagttcatca aaattgtcct gaagcaacat tcattgggcc aaaagaagtg
    13801 gttcgcacgt ggcaaaaatg gggaattcct gaagaaaaaa cgattacagt aaagccaggt
    13861 gatgcagtca aaatcaaaga catcaatgta gtagctttag aagcgtttga tcggacagcg
    13921 ttggtcactt gtgaagatcc agaagaggta ttaaaaggaa aaatgcctca ggagatggat
    13981 caaattgcag taaactattt attcgaaaca tcaggaggga atctttatca tgcaggagat
    14041 tcacattact ccaatttatt tgccaaacat ggtaatgaac acaaaatcga tgtctgttta
    14101 ggggcctatg gtgaaaaccc acgagggata acagacaaag ttacttctgt tgatatgctg
    14161 cgcatggcgg agtcattgaa tgcaaaagta gtgattcctg tccactacga tatttggtct
    14221 aattttatgg ctgattcaaa agagatcact gaaatttgga aattcaaaaa ggatcgcctg
    14281 aagtatggat ttaaacctta tatctggcaa gtaggcggga aattcatcta tccgacaaac
    14341 aaagatgatc ttgagtttaa tttttatcga ggatttgaag atgtcttctc gattgaaaat
    14401 gatacaccgt ttccgtcgtt tttataagaa agaaggggag tttcttgctg aaatactttt
    14461 ttgaccatca attgattcat tacccagata aagaaatcac ggattggcgt gaagctatcg
    14521 ccgaaagctg tcttgtattg atcgataagg aaattattga tgaaacgtat gtggaggaga
    14581 tcatccattg tgtagaaaaa tacggtcctt atattgtgat cgcacctcaa gtagcaatgc
    14641 cgcattcttc agaaaaaagt gatggtgttt ttggaacagc tatttcattt accaagttga
    14701 aacagccaat ccgttttgaa agtgaagggg aggatgagga gaaaacggct agtttgtttt
    14761 ttacacttgc agcaaaagat ccagaagaac atctagaaaa tatccaaaaa ttatccgaat
    14821 tattaatgac agatggattg gttgagcgtc tcatctctac gaactccatc gatgattacc
    14881 aagttgtgat ggcagaatat aattaattga tagaggagaa aaaagatggg ggaatttttg
    14941 ttaagcattt ggacgtattt tgcaacaaat atcttgacgc agccagcata cctgattggt
    15001 tttatcgtgt tattaggcta tattttgctg aaacgcccgc ttcatgaatg catcgctgga
    15061 ttcttaaagg caacggtcgg ttactttatt ttgactgttg gctctggtgg tttggtcaat
    15121 aattttcggc cgattttggt tggactaaag gaacggttca atttggatgc catggttaca
    15181 gatccttatt ttggacaaaa tgctgtggat gctggattaa tggagacatt tggccgtacc
    15241 tttggagatg tgatgatttt attactgatt gcatttgttt taaatatctt attagtccgt
    15301 tttcagaaat atacgaaact gcgttccgtt ttcactaccg gaaacgttca ggttcaacaa
    15361 gcagctaccg ctttttggat tttactgttt tgctttcctg atctaggtag gatacaagta
    15421 ttgattttta tgggactgat tttaggttgt tattgggcag tagcttctaa cttaacagta
    15481 ggaatcacgc aggaattgac agaaggtgcc ggatttgcag tggcacatca gcaaatgttc
    15541 ggaatcttta tatttgcaaa attagctgag tggatgaaaa agcgggatga aaagaaaaat
    15601 agatcaatca agcaagacaa aaaaatcgaa gatatcaaat taccaggatt cttgtcgatt
    15661 ttcaatgaga atatggttgc tacttcgtta ctcatgctat ttttctttgg gatcattctg
    15721 attgtactag gcaaagatta tttgattcaa gcgcaattca tgcaagaagg acagagtttc
    15781 ttattctaca ttatgacgac ttctttaaat tttgcggtat atctggcgat cttgcaatta
    15841 ggtgttcgga cattcgtcga tgaactaact caatctttcc aaggaatctc aaacacaatt
    15901 ttaccaggag ctgttccagg aattgacgta gctgctactt ttggctttgg ttcgccaaat
    15961 gcggtaacga ttgggttctt gtttggtgct ttgggacagt ttttgatgat tggtttactg
    16021 attttattga aatcaccaac gatcgtcata gccggtttca ttccgttgtt ctttgataat
    16081 gccgttatag cagtttatgc caataaccga ggtggattca aagccgcttg cctgttcccg
    16141 tttctttcag gaatcataca agtaggcggt tcagcattat tcgctacatg gattgggatg
    16201 tcaacatatg gtggttatat cgggatgttc gactgggcaa cagcttggcc attgtttaca
    16261 gtaatcatga aagtcctagg ttatgctgga attgccgtag ttgtcattgg tttattggct
    16321 attccgcagt tacaatatcg gaaaaatcct gagggttatt ttttgattgt agaagactat
    16381 gacacatatg cagaaaagca gagagtataa aagaaaatct gattagacaa cactcataat
    16441 ggagggatta agatgagaat tttagtatcg tgtgcaaatg gatcaggaac aagcttgatg
    16501 atgatgagaa gtgtggaaaa agcaatgaaa gaactaaacg taccaattac caaaatccat
    16561 cattgtgcca tttcagaggg aaaaagttca gctggccaat acgatgtagt ttttacgcca
    16621 gtcaattttt tgaatatgtt tactcaggca gagaaaaaag aagttacagt tatcggtatc
    16681 aaaaatgtga tgtcagccaa agaaatcagt gaaaaatttg ctgaaacaaa gtggtaccaa
    16741 aaaaacaagt aaaggaagga actaagatga gcaggccgaa tttgcaaatt gcgttagatc
    16801 acaatgactt agaacatgca ttaggagatg ttatgaaagt tggtgatgta gtagatatta
    16861 ttgaagtggg cacaattctt tgcttacagg aaggacaaaa agcgattcgc tgtattcgca
    16921 gtatgttccc agataaaaaa ctagtcgctg atacgaaatg tgcagacgct ggaggaacag
    16981 tggcgagtaa tgttgcaaaa gcaggagcag actggatgac agtcatttgt tgtgcaacga
    17041 ttccaactat ggaggcagca caaaaagaaa taggtgaatt gcaagtagaa ctctacggca
    17101 attggacttt tgaacaagcc atggattggc ataacatcgg tatccggcag gtaatctacc
    17161 atcaaagccg tgatgcgctg ttatctggtg aaacttgggg tgaaaaagat ttatcgaaga
    17221 tcaaaaaact gattgaacta ggctttaatg tttctgtaac tggtggatta aatccacaca
    17281 cattacactt atttgaaggg atcgatgtgt atacctttat cactggtcgt ggtattacag
    17341 cagcaaatga tccgatgaag gccgcacaaa acttcaaaga tgagatcatt cgtatctggg
    17401 ggtaaggaaa tggctcaaat tgggatttat gaaaaagcat tacccaaaga tatttcatgg
    17461 aaagaacgtt tttcccttgt aaaagaaatg gacttcgatt ttatcgagat gtcgattgat
    17521 gagacggatg agcggttagc acgattagat tggtctgaag aaaagatagc tgagctgaga
    17581 gaagagatgt tcagctccgg tgtacgtatc cattcgattt gtttaagtgc gcatcggcga
    17641 tttccgtttg gttctgctga tccagaaaag aaaaaagcag cgaaacaact aatgaaaaaa
    17701 gcaatccatt tggcgcataa tctaagcgtc aaagtaatcc aaatagctgg atacgatgtt
    17761 tattatgaag agaaatcaat gaattccaga gaagacttta tcgaaggaat aaaagaaagc
    17821 gtaaaggaag cttctaaata tggcatcatt ctttccgtgg aaatcatgga tgatccattt
    17881 atgaactcca tttcaaaatt tttagaaatc aaagaacaga ttcattcccc ttttctacaa
    17941 gtatatccag acctaggcaa tttgtccgca tggccggaaa ataatccggc tcgagaactt
    18001 gagaaaggga tcgattatat cactgctatc cacttaaaag atacttaccc tgtaacaaaa
    18061 gaatattcag gccagtttcg tgatgttcct tttggtagcg gttgtgttga ttttcttgga
    18121 ttattaagac atttgaaacg tctagattat gatggaacat ttctgattga aatgtggagt
    18181 gaaaaaagcc aagactttcg aagagaaatc cagcaggcaa aagactactt aagttctaaa
    18241 ttgaaggagg ctggctatga tgtcttgtga agaaaaaatt gcagcaatga agcaacgtgt
    18301 ccttgaagca aatctggcat tgccgcgata cggattagtc aaattgactt ggggcaatgt
    18361 gagtgaagtg gaccgtgagc taggagtcat cgtcattaag ccaagcggtg tcagatatga
    18421 atgcatgcaa gcagatcaaa tggtggtaac agatttgtcg ggaaatataa tagaagaaga
    18481 tagcttaaaa ccatcttcag atctccccac acatgttgtt ttgtatcaaa cttttgaaga
    18541 tataactgct attactcata ctcattccac gcactccgtc atgtgggcgc aagcaggacg
    18601 cgatttgcca gcttatggca cgactcatgc tgatgctttt tatggtaagg ttccttgtac
    18661 acgccaatta acgaaagaag aagtaagaga agcttacgaa gttcatacag ggaatgtgat
    18721 tgtcgagacg tttaaggaaa gaaaattaga tccaaacgaa gtccctggag tacttgtcta
    18781 tggacatgga ccgttcacat ggggggattc acctatgaaa gcagtagaaa acagtttgat
    18841 cttagatgaa atttgtctga tggccaaaga aaacgagctg atcaacccca atatatgtga
    18901 aatcccgcaa tatttactag ataaacatta ttttcgcaaa catggaaagt atgcatacta
    18961 cgggcaatag agatgctagg gtaagggtag aaaattaaaa gataacactt gatagagaga
    19021 aacagaggtt gtgaagaaaa tttatcacaa cctttttatt tatcaaaaag gatgcattct
    19081 aaaaggaaag agagatttta aggaatcgag agaatcttta caggagagtt atatgtgata
    19141 gattaaatag tcaaagaact gtattattag agggagaatt gtataagaaa ggaagaaaaa
    19201 aatgaatatt gattccctta tgatcgatga gatttctgaa ttatataaga gcgttggttg
    19261 gacgaattac acaaaagaca ctgcaaggtt agctagagca tttgaacaat ctgaatctct
    19321 gataaagcgt aatggggaag ggaagattat cggaatcgtt cgttggatca ctgattttgc
    19381 gacgatcgca tttattcaag atatcctcat tcatccgagg tatcagcgcc aaggaatagg
    19441 caaagtgctt ttgaatgaag ctttggagaa gatcactagt tatggaccag tccaaatcga
    19501 attattgaca gatgatactg agaaaacaaa aaaattttat gaatcagtag gatttgttca
    19561 agtaaaggaa atgggtggta tttcttatgt catagatact agaagaaaaa aggtgctttt
    19621 tggtaatgac aaataacata taataacgta caaaagaaaa aattctagct tagttcttta
    19681 gaaaaacaag aggatagact tagtatcact caatctatcc tccaatgctc agctatttta
    19741 tttttttact cacctcttta tcaaatacaa ttttttgcaa attcgaacta atataaaaaa
    19801 tgaacacatg attttttttt aaagcaaatg ctatgcgata atttttttta ttaattttga
    19861 ctttcatctc gtatattcct tttgccgaac gagtacgcac tggctttata cgaaaaaaat
    19921 tatgctccaa atactctgtc actttgtggg aaattgcttc tttatacatg aaatgttctt
    19981 cttgtggaaa ttgcttaagt agttcactgt caaattcaac agtataatcc atgttttatt
    20041 tcctttctat actgatacat tataaaaata aacaatttta taagtctcta tatttcatga
    20101 tgaatgacaa gtatatttga ttcatcttga tatagctcta cgagatctcc aattccagga
    20161 tacatattga aataatcata tggtatacaa acatttattt tttttcaatt gtcaacactg
    20221 cgtcttcttc ttctaattct ataatcttag caatttgtac gtcgcttttc atgtgtgatc
    20281 ttcctttcta tacattggat ttacttttcg atgatatcta caacagcttt gccacaagtc
    20341 agttcttttt ctagctcgtt ctttattttt atggcacatg gtttggaaaa aggagcagct
    20401 tctttccatg aaccaagtaa aggatattcg ttactgatac ctttcacata ttgtttgttt
    20461 ttgacgcctt ttgtttttac ttctacataa tacatttgat cctcttcttt cttgctgttt
    20521 ttagttaata ttcaaatata tgtaagtgaa aatgattatg tatctatatc tttatgataa
    20581 ataaaaagaa tcaatttgaa agtttttttc actcgatata actaatttga ataatatata
    20641 taataaaagg ctattgttct taaaatataa atagtatata aagagattga aggtaatgct
    20701 cgaatgaaca ttaccttcaa tcttaatgat gcttataact aacgtaataa aaacctgaaa
    20761 caaaaatagc tccgccgatg atatttccaa tataaacggg gataaaattc gagagaaatt
    20821 ctaaccaagt cgcttgacct tcaaatatgg cagcaggtat cacaaaacag ttggccacac
    20881 tatgctggaa accgattgcc acaaaaatca tgactggaaa ccaaatcgtt agtactttgc
    20941 cggccgcatc ttttgctcca tatgataacc ataacgctaa accgacaaac caattacaac
    21001 ctattccgga gcctaatgct tgccaccaag aaacagcgat tttatgatca gcaatatgaa
    21061 tcacttggtc gagatagaca cctgaatgag ttaaaccaac aaagtgtcca aagaaatagg
    21121 caacgaaaat tgcaccaata atatttgcaa aagtaatcac tgaccaattc ttaaccagct
    21181 gtgagaatgt gactttttta tccataaagg caatcgccac agccatcata tttccggtga
    21241 tcaattcacc accgccaaga aggatgacca gcaggccgat aggaaaaacc gaggcaccaa
    21301 ctaaactagt caagctagcc atagattctg ggatagaagc agagactcgt acgtatgcca
    21361 aataacctag agaaatcatg gctcctccga taaaacctaa aatcagttta gctaagatag
    21421 gtttatgtat tttttttgtt ccaagatgaa tactgagttc cataatttct tctggtgtgt
    21481 gcataatact tcgattccta ctttcttaat gaattttcat gtgataaaat atagtgaaaa
    21541 aaatcacatt ttctttgttg attatatcat cttattattt atatgtgcat attattgtaa
    21601 aattttctat ttaatcacat ttgattctaa aaaagaaaca aaaataaaag tcatgtatat
    21661 ggtggtcaaa aagtaaataa tatcagttat caaatttcct gtaaattttc ttgaaactac
    21721 agcatattat tacttcaaaa caatctacat tttttataaa aaaggaaatg aataactgaa
    21781 aaaattatta taggagagaa aaaatgtcaa aatctaaaaa aaatatcacc ataattggtt
    21841 taggcttaac cgtatattta tttacagaat ttgtttatag acatgtgaat ttatttgcag
    21901 aacctttatt tgtattatac gaatcaaatt cctcaatcgt cagtgaactt gctaatttaa
    21961 tgatagcatt gctgtttact cccgcgttga gagtcataac tattttggtc tgtttagtgc
    22021 tattgttttt tgttaataaa aagaaataac gtagtatttc aaaagacaaa gaagtgggat
    22081 gatgattgct atagtatgtt atacgtggtg ctaggtaagt gagaataaac aaaaaaggaa
    22141 acacgcaata aagtttattt caaaacttta ttgcgtgttt cttttttaga ttttttatat
    22201 ctgttgcttt agtagttacc aatagttttc gcttaatcaa tcaaaacgat tttttgttta
    22261 ttgtattctt tacgaacctt ttcaggaatt tcttctgaaa taagataggt aaggtcttca
    22321 attggaccga cgatatgatt actgatggtg ccgaatttat cattagttat catcccaagt
    22381 acttcagtag aaatacgtat catctcacgt ttaatgtcgg attcttgcat agttggcacg
    22441 ctcgttccaa catctagatc tatgttataa atacccataa tataaaggtc ggctcgaatg
    22501 ttttgtagtt gcttataagc ttgtacccca atattgatca tagattgttt ataaaaagta
    22561 ccgccaatat tgataatttc caaattagga tgctgtgcta atgctatggc aatcggcggg
    22621 ctattggtaa tgattgttgc acgaaaatct tgtgggattt cttttgctaa agccaagtta
    22681 gttgtacttc catcaatgat gatgacagat tcttctttta aaaaagggag ggctttatga
    22741 gctaatgcag ttttttgttc gctagctaca gtttctcggt agttaaaatt ggtaattggc
    22801 ggaccaacac gtaaagcgcc gctgtgtact ctttttaaga gaccttggct atccaaatct
    22861 ttcaaatctc gtcgaatcgt gtcttcggat acattgaaac gttgacttaa atcactagcg
    22921 ataacttttt gttctgcgtt taataaatct agaatttttt gatgacgttc taatttcaac
    22981 atgttgcgtg ctccttctta tttattcttg tttatcatgt catttatgcg tttttatgtc
    23041 aataatttcc gtttttaata cactaaaaag gcataaacaa gcaaaaacaa aatattttta
    23101 tgcagtttta tgttgactag tatttgttaa gcggttacaa tgagggggta attaaaggag
    23161 ggaatgtatg gagaaaaaaa ttattttgtc gccttcactt atgtgtgggg atctagcaaa
    23221 tttggaagga agcatccaag aactagaaag tattgggatg gattccttgc atattgacgt
    23281 gattgacggt tcttttagtc ccagtatgcc tttagggatc gaaacaatca aaagaattag
    23341 agaaatcact tcaatgaatt ttgatgtaca catcatggct aaggataacg ataacgaatt
    23401 ttttattgga gaaatgttga aaattggcgt agagagcatt acttttcatt atgaaacaag
    23461 cctccatatt gatcgatata tccagctcat caagaattct ggaacaaaag tagggatagc
    23521 tttgaatcca gcaactccgt taaatgtatt acaatatatt ttacccgaga ttgataggat
    23581 ttgtttgatg ctgattaatc caggttttgc aacaaacaag tcagaaaaac aagtttctta
    23641 cgcgctaaaa aaaattacag atctttgcca gttagtaaat gagaaagagt tagcagtaga
    23701 tatccaagtg gatggacggg tatcgttaga aacgatcccg ggattattag atgcaggcgc
    23761 aacaaatctg gtattaggaa gtacaagttt gtttcttaaa ggaaatacat tagcagaaaa
    23821 tcaaaaacta ctttatcaag cgatgaagca atcagttagg aaaaatcaat agatgtagtg
    23881 gtcctgaata atagaaatgg aggggaaata gttgagttat aaggcggcga aacaaaatat
    23941 tgtaagagaa attactgaaa cattagaccg tatttcttca aaagatgtgg aacaattgat
    24001 aaagaaaatt gaaaaagcgg aacgagtttt tttcgtgggg gttggcagag tactgttagc
    24061 gctagaagga atggcaaaac gcttagggca tctaggaatt cagacagtag tcgtaggaca
    24121 aatcactgaa ccggcaatta cagataaaga tttattgatt gttggttctg gtagtgggga
    24181 aagtgctttc ccactaacta ttgcaaaaaa agcaaaggaa tttgggtccc aagttgccca
    24241 tataggatca aacccagaca gcacaatgaa agaatattca gatcttttta ttcgtatacc
    24301 cgtacaaaca aaattagcgt taccagagga aatttcttct atacagccaa tgactagcct
    24361 gtttgaacaa agtgttcttt tgttaggaga tagtattgct ttagtgatga tagaagaaaa
    24421 agcaattgat atgtcaaagt tgtggcaata ccatgctaac ttagagtagg tgaaaaatga
    24481 aagcggtaca ttttggagca gggaacatcg gcagagggct tattggacaa attctacatc
    24541 agaatggatt cgatctatgt tttattgata cgaatcctga actgatccat caattaaatc
    24601 aagataaggg ttatactatc gaaattattg atgaaatgaa caggagtgat ttcattgatc
    24661 atgttgtggc actgaatagt ttatccgagc tagaagaggt gattacagca acaaaaaatg
    24721 cagatatctt aacaacatct gttggcgcaa taaatttagt aaaaattgca ccgatcattg
    24781 cgcaagcctt aagtaagcga tttgaacaaa agcatagcat caatatcgta gctaatgaaa
    24841 atgtgataaa tgcaagtgat gtgttgaaaa aagaaattta ttctttgctg tcagaaaaag
    24901 aacaagagaa ttttgatgaa tatgcatatt ttgtgaatac ggcaatcgat cgacaatctt
    24961 taggaaaagt tcttggagga aaaatgatct ctgttgtcga accttattat gaatggataa
    25021 tggatcgaca gcagttagat ccaactacat cttttgatat gaaaaatgta aatttggttg
    25081 atgatatgga gccttacatt gagcgaaagc tttatatcgt taatgctgct catgcggcag
    25141 tagcttattt aggcgcactg aaaggatata agacgattca agaagcaatc caaaatatgg
    25201 agattttcaa tctagtcaag caatttttaa tggagaatat agagtacttt gtacaaaaat
    25261 atcatttttc tagagaagaa ttaacatctt ttgtggaaaa aacattaaac cgtcatggga
    25321 atcagaaact ctccgatgaa attactcgtg taggaagttc ccctattcga aaattaggcc
    25381 ctaatgatcg tttaattgct cccatagtaa aactagattc atatcattta ccttacgatg
    25441 caggaataaa agtaattgct gcgggatatc attatcggaa tcttgctgat ccagaagctg
    25501 aacaactacg tcgaatgatt gtaaatgatg ggttgaaagc aacgattaaa aagatttctc
    25561 gtttggaagg taagctgctg aatgaagttg tcgctgctta tgagtcccag atttagagga
    25621 ggagaatatg ctaaaagaac aattgtcagg aaatacaatg tttatggatg cgatcgattc
    25681 atggcaagag gcaatccgag taagtgcgcg tcctttgata ggaaagggaa taatagagga
    25741 aagctatgta caagcgatga tacaaaatgt gttggataac ggaaattata ttatattact
    25801 gccactagta gcaatgcctc atgcgcgtcc agaatttggg agcaaagggg tcgggatgag
    25861 ctttttatgt ttagataagc cagtcatgtt cccaagtgaa gaaccagtaa aattcttctt
    25921 taccttttct tctgattcgc caaagggaca tttagactta atggccaatc ttggagaatt
    25981 gctgagtgat gaaaaaatgt atcaaaaatt attcgatgtg aagacagaaa aagcattgtt
    26041 agatttgata aagaagtaaa ggagagaaga aaatggaggt agcaaacaaa aaaaaacgag
    26101 tctccatgcg agctaaagtt caagcgattg gcggtttctt aacaaatatg gtattgccaa
    26161 atataggcgc atttattgca tggggaattg ttactgcatt attcattcca actgggtggt
    26221 tcccaaatga atctctgaat gaactcgtaa gtccgacagt cagctatcta ttgccgttac
    26281 tacttgccta tactggtggt cggatggttg gtggtacacg tggagctgtt ttaggtacaa
    26341 tcggaacaat aggtttgatt attggtgctg acataccaat gttcatggga gcaatgatta
    26401 tggggccact tggtgggtgg atgatgaaaa aaacagatga ttttttagat gggaaagttc
    26461 ctgctggttt tgaaatggtc gtcaataatt tttctatagg aattattggt ttcatactga
    26521 tgtgcctttc ttatctggta gttggaccaa taatccaatc agctaatcaa tttgtaacga
    26581 gtgcaattga agcattagtt tcaactggtt ttttaccgat actgtcctta atcaacgaac
    26641 cggcaaaagt cttattttta aataatgtta ttgaccaagg tgtttattat ccattaggta
    26701 tgcaacaaac attagaggca ggcagatcaa tttatttcat ggtagcatca aatcctggcc
    26761 ctggcttagg actattgtta gcttattctt tatttggtaa aaaggcagca aaacagacag
    26821 caccaggtgc aatcatcatc cattttttcg gcggaataca tgagatttat tttccatatg
    26881 tattaatgaa accactcact atattatcta tgattgctgg tggaatgaca ggaatcatca
    26941 cttttgaatt atttgatgcg ggcctggtag caggtccaag tccaggttct attttttctt
    27001 atttagctct aacgcctcgg ggaaattttt tgggtgtcat ggcgggagtg gtcacagcaa
    27061 cactggtttc cttttttgta acatcagtaa ttttaaaagc agataaatca acagatgaag
    27121 acagaaattt tgaactatca gttcaaaaat cgaaaacgat gaaatcagaa ggaagaaaat
    27181 tattaaaaga agaaaatgct agagaaatat gtaccgagaa aaaagagatg aataaaattt
    27241 cctttgcttg tgatgcagga atgggaagca gcgcaatggg cgcaacaata ttcaagaaaa
    27301 aattgcaaaa agcaggtatt actgatgttg agataaaaaa ttatcgaatt gaagaggtac
    27361 cagaagatag tgatttggtg atcgtacatc aagatttgga ggaacggact agaaaagcac
    27421 atcctaacat gaaaattgtg acattaaaga attatttgca agatccagta atcaatggat
    27481 tagcagaaga aatcattgga ttaaaaacag aagactaatt tatgggaatt tttgattaac
    27541 ctttattaaa attattttgc ctaatataaa aaggttgtga catggcttgt gtcgcaacct
    27601 ttttttgtcg cacaaataat taatcggata ttttatgttc atattttttg tgatcaacga
    27661 gaactgatgg ggcaaagata cattttagat acttttaact gttaatttac aaaacaaggt
    27721 gaaacgaata gaaaaatgaa aaaatcgata cggaagaata tgtttgatta aaacatgcat
    27781 gaagagaagg aggttgatga tacatgaaaa aaatatattc aaaggaaatc gattgtttta
    27841 gaggcattgc tgttttagca gtgatatttt atcatttgcc aaatagtttg ctgccaggcg
    27901 gattgcaagg agtaacgatc ttttttgtgg tttctggttt tttaatggct aaaaatacga
    27961 taagagatga aaaaaacaga caattcagtt ttttacattt ttactataag cgtatcaaac
    28021 gtatttatcc atttttactg ttttctttgg tcgtattcat tttcatacta gggattagca
    28081 acattcgatt gataggaaac attcgtagtg agctacccag tttgattttt ggctataaca
    28141 attggtggca gctgaatcaa ggagtatctt attttgactc ttactttaat gcttctttat
    28201 ttaaacatta ttggtcgctt tcagttgaac tacaattcta tttgatatgg ccatttttgt
    28261 ttattgtcat taagcgtatg agaagaaaac aagtgtttta cttaatctat acattgattt
    28321 ttgtttctat tctttttagt ttgtttttac cttcaactaa ggcatattat catacgatag
    28381 ctaaactttt tccattttta ttaggagttt gggggtattt taatcgaata actattggcc
    28441 gtttctttga acaaaacact tttagtaaaa tctggctttt attactagct agtctttgtc
    28501 tgattctgtt cccgattttt ccttatacac taaatgaact actgatcagt atttgttttg
    28561 ctctattgtt agccagtgtc gatgatatga acattgcaaa aaagaccaaa atcgctagta
    28621 caaaactttc ttttgtagga aaaatcagtt atgaacttta tttggtgcat ttcccagtat
    28681 tgattgctct gacaaatcta ttcaaacatc accattggaa atatttggat atcgcaggtc
    28741 tattcactgt gtttttatgt acattactca tgattacttg ctttagaaaa ggagtgcaaa
    28801 agatgagatc acccaaaatt tggacagcta tggcactaat gataatcgga gtttctgtac
    28861 tggtattacg tgctcctgcc agtcgactga ccgctgacca aaatcagttg caaagtttat
    28921 taaaagaaaa ctctagtaaa gcaaatgcag gagaaaatct gttgtcacaa gagaagaaaa
    28981 tattatttat cggtgattct gttatgctgg gggcgtatca ggaactaaag gagacattta
    29041 aaaaagaagc attggtagat gcaaaagaat caagacaaat cactgcgtta ccagaaatct
    29101 taaaggagca taaagattta gtttcttacc aacaaatagt gatcgggtta ggaaccaatg
    29161 gtgtgataac agatgaagct atagaacaaa caatgtcttt gctgaaagat aaaaaagtat
    29221 actgggtaaa tataaaagca ccaactggct ggcaagatac gataaatgcc acattagcta
    29281 cattgccaaa tcagtattct aatataacga tgatcgattg gtatagtgag agcaaaaatc
    29341 atcctgaatt tttttatgat gatgaaaccc atttgaatga aagtggacgt acagcttatg
    29401 caaagtatat tgcttcagtt attcaataag gtagtgatta cgtgtgttaa ccttactttt
    29461 tcctaatagg tgaatcaatt taaataaaaa atacttcata tgataaacgg tgtttaagag
    29521 gaggagcttt ttaatattcg tggtaaaaaa gagatgggcg aggtcgttaa ctgagagctt
    29581 cttggaaaga aatcgctttg gatttatcct ctttgttata cagaacatga gcgagacgac
    29641 aatactagga tgtatgttct gatcgaagtt ttatggttac aagcagcaat cagcttagat
    29701 aaaattaagg atcgtaggaa ccaagtaaag aaggctgtta gtaaagaaac aaacgatcaa
    29761 gtatgtttta ctcttaagaa gatgcagtga ataaataata gtaatataat gctagaaggg
    29821 actgtgacaa aagacgtgtc acagcctttt ttgttatttt aattatcgtc cagtcttttt
    29881 ttataaatga ttgcttaagc attaaatatt aaaaaatata gagttcaaaa ttactgcaca
    29941 attagatgaa aaatttgaac aacaaaaagt gtatttttat actataatag cttttgaatt
    30001 tagttactct attcaaaagt tatgctatgg acaagaaaaa gaataaatag aggtgagaaa
    30061 atgaatagtt tcaagaaaaa atttgtgagt agatttttaa atatgaaaaa tttttttgaa
    30121 aaaaagggag attatgatgc atataattat gtattaaatc tagaaaagca aacatattat
    30181 acactacgta aaaacgatga taatgacttt tggactatgt tacctaaaat gctttcgatt
    30241 gactctaagc tttccctttt agaggaattt attaatttag acattgaaga attttgcggg
    30301 ggaaaagagt taattaatat ggtagagagt gattatcata cctattataa agaaagttgt
    30361 ggatacaaag tggatgagca atgtccacaa tcaattattt tttacattga gtaatatgaa
    30421 ctattaagca ggaaagcggg agcgtcaata attttgtgta aataaattgt cctcctgcaa
    30481 aataattagt ta
//
LOCUS       DAPBCF010000031        28987 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.031, whole genome shotgun sequence.
ACCESSION   DAPBCF010000031 DAPBCF010000000
VERSION     DAPBCF010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28987
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.031"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            12..84
                     /locus_tag="RD508_001719"
     tRNA            12..84
                     /locus_tag="RD508_001719"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Val,seq:tac)
     gene            88..160
                     /locus_tag="RD508_001720"
     tRNA            88..160
                     /locus_tag="RD508_001720"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Lys,seq:ttt)
     gene            168..249
                     /locus_tag="RD508_001721"
     tRNA            168..249
                     /locus_tag="RD508_001721"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:202..204,aa:Leu,seq:tag)
     gene            267..339
                     /locus_tag="RD508_001722"
     tRNA            267..339
                     /locus_tag="RD508_001722"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Thr,seq:tgt)
     gene            351..422
                     /locus_tag="RD508_001723"
     tRNA            351..422
                     /locus_tag="RD508_001723"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Gly,seq:gcc)
     gene            439..524
                     /locus_tag="RD508_001724"
     tRNA            439..524
                     /locus_tag="RD508_001724"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Leu,seq:taa)
     gene            535..608
                     /locus_tag="RD508_001725"
     tRNA            535..608
                     /locus_tag="RD508_001725"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Arg,seq:acg)
     gene            618..691
                     /locus_tag="RD508_001726"
     tRNA            618..691
                     /locus_tag="RD508_001726"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:652..654,aa:Pro,seq:tgg)
     gene            711..783
                     /locus_tag="RD508_001727"
     tRNA            711..783
                     /locus_tag="RD508_001727"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Ala,seq:tgc)
     gene            811..884
                     /locus_tag="RD508_001728"
     tRNA            811..884
                     /locus_tag="RD508_001728"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:845..847,aa:Met,seq:cat)
     gene            898..971
                     /locus_tag="RD508_001729"
     tRNA            898..971
                     /locus_tag="RD508_001729"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Ile,seq:cat)
     gene            995..1084
                     /locus_tag="RD508_001730"
     tRNA            995..1084
                     /locus_tag="RD508_001730"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Ser,seq:tga)
     gene            1097..1170
                     /locus_tag="RD508_001731"
     tRNA            1097..1170
                     /locus_tag="RD508_001731"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Met,seq:cat)
     gene            1189..1264
                     /locus_tag="RD508_001732"
     tRNA            1189..1264
                     /locus_tag="RD508_001732"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1222..1224,aa:Asp,seq:gtc)
     gene            1266..1336
                     /locus_tag="RD508_001733"
     tRNA            1266..1336
                     /locus_tag="RD508_001733"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1298..1300,aa:Gly,seq:tcc)
     gene            1350..1423
                     /locus_tag="RD508_001734"
     tRNA            1350..1423
                     /locus_tag="RD508_001734"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Ile,seq:gat)
     gene            1448..1535
                     /locus_tag="RD508_001735"
     tRNA            1448..1535
                     /locus_tag="RD508_001735"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1482..1484,aa:Ser,seq:gct)
     gene            1557..1628
                     /locus_tag="RD508_001736"
     tRNA            1557..1628
                     /locus_tag="RD508_001736"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Glu,seq:ttc)
     gene            1651..1740
                     /locus_tag="RD508_001737"
     tRNA            1651..1740
                     /locus_tag="RD508_001737"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Ser,seq:tga)
     gene            1753..1826
                     /locus_tag="RD508_001738"
     tRNA            1753..1826
                     /locus_tag="RD508_001738"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1787..1789,aa:Met,seq:cat)
     gene            1845..1917
                     /locus_tag="RD508_001739"
     tRNA            1845..1917
                     /locus_tag="RD508_001739"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1878..1880,aa:Asp,seq:gtc)
     gene            1921..1993
                     /locus_tag="RD508_001740"
     tRNA            1921..1993
                     /locus_tag="RD508_001740"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1954..1956,aa:Phe,seq:gaa)
     gene            1998..2068
                     /locus_tag="RD508_001741"
     tRNA            1998..2068
                     /locus_tag="RD508_001741"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2030..2032,aa:Gly,seq:tcc)
     gene            2081..2154
                     /locus_tag="RD508_001742"
     tRNA            2081..2154
                     /locus_tag="RD508_001742"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2115..2117,aa:Ile,seq:gat)
     gene            2166..2237
                     /locus_tag="RD508_001743"
     tRNA            2166..2237
                     /locus_tag="RD508_001743"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2199..2201,aa:Glu,seq:ttc)
     regulatory      2426..2505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            2503..3696
                     /locus_tag="RD508_001744"
     CDS             2503..3696
                     /locus_tag="RD508_001744"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDT7736306.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3826..5298
                     /locus_tag="RD508_001745"
     CDS             3826..5298
                     /locus_tag="RD508_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7736307.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            5381..6169
                     /locus_tag="RD508_001746"
     CDS             5381..6169
                     /locus_tag="RD508_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDT7736308.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6236..6904)
                     /locus_tag="RD508_001747"
     CDS             complement(6236..6904)
                     /locus_tag="RD508_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HDT7736309.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            7019..8731
                     /locus_tag="RD508_001748"
     CDS             7019..8731
                     /locus_tag="RD508_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7736310.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8734..10503
                     /locus_tag="RD508_001749"
     CDS             8734..10503
                     /locus_tag="RD508_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7736311.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(10708..11274)
                     /locus_tag="RD508_001750"
     CDS             complement(10708..11274)
                     /locus_tag="RD508_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDT7736312.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(11274..12230)
                     /locus_tag="RD508_001751"
     CDS             complement(11274..12230)
                     /locus_tag="RD508_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDT7736313.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(12230..12886)
                     /locus_tag="RD508_001752"
     CDS             complement(12230..12886)
                     /locus_tag="RD508_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDT7736314.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            13256..15274
                     /locus_tag="RD508_001753"
     CDS             13256..15274
                     /locus_tag="RD508_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7736315.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    15344..15550
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15701..18115
                     /locus_tag="RD508_001754"
     CDS             15701..18115
                     /locus_tag="RD508_001754"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDT7736316.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            18463..20016
                     /locus_tag="RD508_001755"
     CDS             18463..20016
                     /locus_tag="RD508_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDT7736317.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(20397..22181)
                     /locus_tag="RD508_001756"
     CDS             complement(20397..22181)
                     /locus_tag="RD508_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7736318.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(22196..23917)
                     /locus_tag="RD508_001757"
     CDS             complement(22196..23917)
                     /locus_tag="RD508_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7736319.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            24017..24778
                     /locus_tag="RD508_001758"
     CDS             24017..24778
                     /locus_tag="RD508_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7736320.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            25745..26013
                     /locus_tag="RD508_001759"
                     /pseudo
     CDS             25745..26013
                     /locus_tag="RD508_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            26685..>28987
                     /locus_tag="RD508_001760"
     CDS             26685..>28987
                     /locus_tag="RD508_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736321.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVET"
BASE COUNT         9084 a         5218 c         6183 g         8502 t
ORIGIN      
        1 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
       61 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      121 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      181 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      241 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      301 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      361 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      421 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      481 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttcaa atatgcgccc
      541 atagctcaac tggatagagt gtttgactac ggatcaaaag gttaggggtt cgactcctct
      601 tgggcgcgtt aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa
      661 ggggtcgcag gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag
      721 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
      781 ccatttcatt taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc
      841 ggttcatacc cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga
      901 cctttagctc agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc
      961 tacaaggtcc attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag
     1021 ggaacggtct tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc
     1081 tcctttttca tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga
     1141 aggtcgtagg ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg
     1201 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
     1261 gccatgcggg tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg
     1321 attctcgtca cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg
     1381 cctgataagc gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat
     1441 tggttttggg gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg
     1501 aaaccggcgc gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc
     1561 cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt
     1621 acgggtcatt aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa
     1681 cggtcttgaa aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct
     1741 ttttcatatt atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt
     1801 cgtaggttca aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg
     1861 ggttaacatg cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt
     1921 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt
     1981 ctgtcccgcg ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt
     2041 gtcgcgagtt cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt
     2101 tagagcgcac gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt
     2161 ttattggccc gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc
     2221 gaatcccgta cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga
     2281 atgattttaa aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga
     2341 cagttctaat gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag
     2401 aaaactgttt tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg
     2461 gagatgcctt gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta
     2521 tttacatcag aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat
     2581 gcaatcttgg atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct
     2641 gtaacaactg gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt
     2701 caaaaagtcg tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt
     2761 gatggagata cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa
     2821 ggagttgatg aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt
     2881 ggtgctggtg accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg
     2941 cctttaccaa tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca
     3001 aatgaattaa cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat
     3061 caaggacaac cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta
     3121 gataatgaaa caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct
     3181 gaattattag atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt
     3241 ggtcctcaag gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt
     3301 tatgctcgtc atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct
     3361 gccagctatg ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa
     3421 gcagaagtac agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat
     3481 actttcggta ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc
     3541 gatcttcggc cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa
     3601 acagctgctt acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac
     3661 aaagtagatg cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc
     3721 caagtggtgg ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt
     3781 atttatctat ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca
     3841 aatgttactt tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt
     3901 acaatcgtaa caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg
     3961 aactgggtat tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa
     4021 cttgcggata aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc
     4081 ggttcgttat tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt
     4141 caagggatgg gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat
     4201 tctattgaaa agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt
     4261 gtttttggac cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt
     4321 tttatcaatg tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa
     4381 ccaaaaatca tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc
     4441 atgcttgtct cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt
     4501 gtttctgctt tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa
     4561 agagctaaag atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc
     4621 aacttggctg cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg
     4681 tggatgcaag gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta
     4741 tcactagtct ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact
     4801 cattgggtct tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt
     4861 atgcctttca gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc
     4921 ttaggtgtga ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag
     4981 cttggtgtag caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt
     5041 tctatttttg gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta
     5101 acaaatgatg cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat
     5161 gcggatattt tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta
     5221 gttggcttgt tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt
     5281 ggtaaaataa aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa
     5341 agttattcaa aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa
     5401 tatttattcg aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac
     5461 aaaaaaggtg attggcacca gttcagagca agagacaacg gatatacctg ttttatattt
     5521 acttcatgga atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta
     5581 tgtagcaaac tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga
     5641 tacagtttat gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca
     5701 tgaattattc ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat
     5761 gggcggatat ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat
     5821 ctctctttca ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa
     5881 agcatctttt tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga
     5941 tccgcaatac ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat
     6001 ggcttgtggg gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca
     6061 ggaacaaggc ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg
     6121 ggaccaatgg attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct
     6181 taaaaagata gctcctatag agatcacaaa catagtgatc tctataggag cttttttact
     6241 gctcgttttc tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg
     6301 ttagaaagag tgctttttca ttcaattctg catgggactg catactttct ttaaatccct
     6361 ctaattgatt ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat
     6421 ttccgtccat aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa
     6481 tcaataaatt gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac
     6541 gaacaagtaa ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag
     6601 tattgatttc taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca
     6661 tatactgcag caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt
     6721 ccattgtttc agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag
     6781 caggtgcttg aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt
     6841 gtgtttcagc caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt
     6901 ccattttatc aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt
     6961 ctaattttac agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat
     7021 gaaattaatc ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc
     7081 cgtagcagtc atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga
     7141 agctattatt acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct
     7201 ggctttgcta ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca
     7261 aggcgtaagt gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg
     7321 aaatatcgaa cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca
     7381 aatccaaaat ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat
     7441 tggtgccttc attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct
     7501 tatcgttacg gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat
     7561 gatcattcaa aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat
     7621 tcgtgtagtg aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag
     7681 tgaggactta acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc
     7741 cttcatgctg gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt
     7801 taaagatgat cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat
     7861 tatgatggca atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc
     7921 gctgaagcgg attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc
     7981 agaacaagag ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga
     8041 ggatacagat acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat
     8101 cgtcggggcg actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga
     8161 tccgacagaa ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag
     8221 tttaagacaa acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc
     8281 tcaaaacttg cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc
     8341 tattgctcaa gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga
     8401 agaacgtagc agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt
     8461 tatcggtaat ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc
     8521 tgaaaagctg gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat
     8581 cgcacaaaaa attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag
     8641 attagtcggc gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat
     8701 ctttgaaact caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa
     8761 tttttctatc actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg
     8821 atcattgcta cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa
     8881 ttagctaatt acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct
     8941 gtaatatgga aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt
     9001 attttgttca cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac
     9061 aaattggaaa aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt
     9121 cgttttacca gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc
     9181 atcacgaatg ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag
     9241 ttagcttggg ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc
     9301 cgcaaagcac ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat
     9361 atggatgaaa aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg
     9421 attgaaggat tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct
     9481 tattctggtc tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt
     9541 atctttttcg gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc
     9601 ttagttgtga cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca
     9661 tctggataca gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt
     9721 gatgaaaaag atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt
     9781 cttgcgttgc agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc
     9841 tcgatcaatg tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa
     9901 acgacgatca tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc
     9961 gatggaatag atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt
    10021 ttgcaagaat ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg
    10081 gacgcttcag atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc
    10141 atgacgttag aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca
    10201 ggtcaaaagc agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt
    10261 ttggatgaag caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg
    10321 gatgaagcaa tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg
    10381 aatgcagata gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac
    10441 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
    10501 taaagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaaacag
    10561 cttctcatgt ttttgatttg gttggactta ttaccgcaga tataagcttt tgagcaccgt
    10621 gaataaagag gttatgaaat caacgctcta acctgagtat tagagaaaaa aacgcaaaac
    10681 atatcattta tgttttgcgt tttttattta tctttttttc tcaatacaat ataaaatagg
    10741 cggctggttc ttttggttga taaaccgata attcagcaca ttatatgttt cctgtggcag
    10801 tttggaacaa aaagaatcaa ccatatccag ttctttttct ccaccttcat gaccatagta
    10861 gacgacaagg atcaatcgtc cgcgaggcac aagtcgtttc aatatttctt ccatagctgt
    10921 gcgtgtagtc tctggcatag tgatgattgc tttatcactt tttgggagat accctagatt
    10981 gaaaatccct gctttgagat tttgttgttc agctatcact tctcctaacg tttcgtggcc
    11041 ttgtagaaac aatgagacac gttcttctaa ctgacgctgt tctagccttt cacgagtagc
    11101 atcgattgct tgttgctgga tatcaaaact atagacatga ccagtttttc cgatgtgttc
    11161 tgctagaaaa accgtatcgt ggccattgcc catcgttgca tctacgacgt gatcccctgg
    11221 ttgcaagatt tcttgcagta atgtatggct gaaatgcaaa gcagtttgca acatcagacg
    11281 ctcacctttt tccgtacatc atattttcct tggaagctat ctctgcgaag aagttcttca
    11341 tcaattgcat tcaagacttc ccattttttc aagctccaca ttggtccaat caaggaatcc
    11401 cacggcgcat cccctgtcaa acgatggatg atgatctctt ttggtatcat ttccagctgg
    11461 tcgcaaatga cattgacata gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag
    11521 tcccgcaaca ttctcgtttt gcgcatcaga tgcatcaaat ggagcttgat tccttggata
    11581 tctgaatcta aaatggtgcg tctgacattt tctttcatca tttctaaact ttcgcctggt
    11641 aatccgttga tcaaatgcgt acaaacacgg atattatgtt tgcgtaattt agccacgcca
    11701 tctaaataag tttgataatc atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt
    11761 gtttgcaatc caagttctac ccataaatac atccgctcgt tcagttcagc aaggtaatca
    11821 actacttcat ctggcagaca atccggtcgt gtaccgactg ataatcctac gacacctggt
    11881 aaattgacta cttgctcaaa tcgttctttg attatttcaa ctggcgcatg ggtgtttgta
    11941 aaattttgga aataaacgat gtattgttgg acatgaggcc atttttgatg catcatgtcg
    12001 atttctttct ggaattggat tggaagaggg tcttcaggtg caacgatcat gtctcccgaa
    12061 ccagatacac tgcaaaaagt acaaccgcca tgggcaacag tcccatctcg attcggacag
    12121 tcaaatcctc catcgatcgg caccttgaaa attttcccgc caaactcatt tcgtaaagcg
    12181 taattccaag aatgatatct tttatttcct tctgaataag gaaaagtcat taaaagtcct
    12241 tctttctgta agagttatct atttgttttc ttttttctct atacactgga taagtcaggc
    12301 acagccaaga aagactgagt aagtagccgc cgatgatatc agtaggaaaa tgaacgccca
    12361 gataaatgcg gcttatcccg acacttacta taataaacat catcagcaat tgaagcaatg
    12421 tgcgtaaggt tcttttttga acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa
    12481 tcatactgcc tgctgcatgt ccactaggga aactgtaact tgtttcaact actaagtgcg
    12541 ccaatgaagg acgctctcgc atgaaaaata gtttgatcac cgggttgatg attccagcaa
    12601 ttacaataaa tccagaaacg aaccaaaatg tttctgccct ttttttctta taccacatcc
    12661 ataaagccgc acaagcaaat aaaatgatga cggtaagagg attaccgaat ttagtcataa
    12721 agagttggta gctgttcaga tcaggataag aagctctgac aatgcctgta aaccactgat
    12781 cgaaaccaga aagccacgac agatggaact ttacgatcca gcccaaaatg aaaaacagga
    12841 caagaaagaa gctaccagcc acctgaaatg atgttttata tttcatacaa ttcctccttt
    12901 gaagcaatga cttattatag catttttggt ccagcgaaaa aaacggtaaa gagataaaac
    12961 caatgtatga ttcctctttg aataaccaat attcttataa aaaaaataac tgtaatcgga
    13021 aagacatttt ttggtaatgc aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa
    13081 tccttttaaa caagaacgta gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt
    13141 acggtaaatt acaatatgat tacaaaaaac aacaaagctc ttaaataact tttaataaat
    13201 attaagagaa gttataatta ttaataatag ataaattgaa gttggaggat agaagatgga
    13261 aaacattgca agaaaagaac ggagacgttt agaacagacc aaacgttttc gaaaagcaaa
    13321 acgaggggca gcaatcgtgg gaactgcgat ggtaggctgt tctgtcgctg ccccattagt
    13381 acagccggtt cctgttcaag cggatgaaac acctgttcag ttcggcgcaa gaatcaatac
    13441 agcggcattt atcacagaaa ttgctactta tgctcaacca atcgctcaag ccaacgatct
    13501 atatgcatca gtgatgatcg cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt
    13561 atctcaagca ccttattata atctttttgg gataaaaggc agctatcaag gacaaaccgt
    13621 ctacatggat acgcttgaat ttttaaataa tcaatgggta aataaaaagg agcctttccg
    13681 acaatatcct tcttttgctg aatctttcaa tgacaatgcc tatgtactta gaaatacttc
    13741 atttggcaac ggttattact atgccggtac ttggaagagc aacacgaaat cctatacaga
    13801 tgcgacagct tgtttgacag ggcgttatgc gactgatcct ggttacgcag gcaaattaaa
    13861 taatatcatc gcaacttacg gattgaccca atatgataca ccagctagcg gaaacgcagg
    13921 cggtggagcg actacaggtg gcaataatac tggaagtgca ggtagtactg gcggttcaag
    13981 caattctggt aatacaaact caggttcagc aacttcgacc acttatactg tccaatctgg
    14041 tgattctgtt tggggaatct caaataaatt cggtatcaca atggatcaat tgatccaatg
    14101 gaacaacatc caaaacaatt tcatttatcc aggacaaaaa ctgacaatca aaggtagcca
    14161 ggaaaatggc tcttcgacga ataattccgg taacaatacc aactcttcag gaaatgctgg
    14221 tacatcaaac ggaggacaaa caactggtgc gaaatacact gttcaatctg gtgattctgt
    14281 ttggaagatc tcaaatgatc acggaattac gatggctcaa ttgattgaat ggaacaatat
    14341 caagaacaat ttcgtttatc caggacaaca gctaatcgta tcaaatggcg gttcttctaa
    14401 tgctggagca aatactggct caaatactgg gaatacaagt ggctctagtt cgtccagctc
    14461 aagttcttct aatacagctt caggaacgaa atatacagtt aaagccggag actctgtttg
    14521 gagcgtctca aataaatacg gaattacgat ggctcagcta atccaatgga acaatatcca
    14581 aaataacttt atctacccag gacaacaact gactgtttca aacagtggat caacaaacag
    14641 cacgtcaggt aatacaggtt cgtcaaccaa tacaaataac agcagttcag ttaatactgg
    14701 cagcagttcg tctcaaggca cttataccgt gaaagcaggt gaatctgttt ggagcgtggc
    14761 aaataaaaac ggcatcacga tggatcagtt aatcgaatgg aataatatca aaaacaactt
    14821 catttatcca ggacagcaat tgatcgttaa aggtggaact tcggcaaata caaatacagg
    14881 ttcaactact tctgcagcga aaccaaatac accgaatacg tctgctacga caagtacatc
    14941 atccactggt aatacgatgt ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa
    15001 caaacatcat atcacgatgg atcagttaat cgaatggaat aatatcaaaa ataatttcat
    15061 ctatccagga cagcaagtga ttgtgaagaa aggttcatct caatcaacaa accaacaatc
    15121 agttactggt tcgaaaacct atactgtgaa atctggagaa tctgtttgga gtgttgctga
    15181 cagtcatgga attacaatgg ctcaactaat cgaatggaac aatattaaga acaactttat
    15241 ttatccaggt caaacgttga ttgtagctaa ataaaatagc tgttcgaaga aataacgatt
    15301 gaattccaca aaaatatttg ttactataag gctacttaaa tatgacaaca cttgaaaagg
    15361 aagtagtaaa aagactgaag tttcagagag cgcatggctg gtgagaatgt gcacggatgc
    15421 ttttgaactc gcctttgagt tgcccttgct gaatacccga gtaagcaagc ggcggtgacg
    15481 gccgttacaa cgttcgaggc cttttcacta aggtaaaatt aggtggtacc gcgtagatta
    15541 cgtcctataa aaagagcaat ctttttatag gattttttta tttcttttgt gaagtttgag
    15601 aaaacaaagc aaaaggaaat aaaaataaac agattctgcc ggttttttcg ttatatttat
    15661 aatagaaaca agtgttttca atagaacagg aggacagcaa atgagttaca atcataaaga
    15721 aattgagaaa aaatggcaaa aatactgggc aaaaacgaat actttcaaca cccatgatga
    15781 tcctgaaaag ccaaaatttt acgcactgga tatgtttccc tatccatccg gtcaagggct
    15841 acatgtaggg catcctgaag gttatacggc aacggatatc ctttcacgtg tgaaaagaag
    15901 tcaaggatac aacgtgctgc atccaatggg gtgggatgca ttcggtctgc ctgctgaaca
    15961 atatgcgcta gatacaggaa acgatccagc tgagtttacc caaaaaaata tcgaaacatt
    16021 ccgacgccaa atcaattctt taggatttag ttatgactgg aatcgcgaag tgaatacaac
    16081 tgatccggag tattataaat ggacacaatg gatctttacg aagctttatg aaaaaggtct
    16141 agcttatgaa gcagaagtag cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa
    16201 tgaagaagtg atcgatggga aaagtgaacg tggtggctat gatgtagtca gaaaaccaat
    16261 gcgccaatgg atgctgaaaa tcactgctta tgctgatcgc ttattggatg atctagaatt
    16321 agttgattgg ccagaaagca ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg
    16381 agcaaatatt gaatttaaag tggctggtac ggataaatcc tataccgtat ttacgacacg
    16441 accagatact ctattcggtg caacttactc ggttcttgca cctgaactag atcttgttag
    16501 agaaattacg acccctgaac aaaaagctgc tgtagaagct tatatcgaag agacagctaa
    16561 aaaatcagat ctaaagagaa cggatcttgc aaaagaaaaa acaggagtat ttactggtgc
    16621 ttatgcaatc aatccagtta atggcaagga aatcccaatc tggatcgccg attatgtatt
    16681 atcttcatac ggcacaggag ccatcatggc tgttccagca catgatgaac gtgactttga
    16741 attcgctcaa actttcggac tagaaattct tccagttatc gaaggtggag atgttgaaaa
    16801 agctgcttac acagaagatg gtacgcacat caactctgaa tttctagacg gcatgaacaa
    16861 acaagaagca atcgataaaa tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga
    16921 agtcagctat cgcttacgtg actggctatt ctcccgtcaa cgttactggg gtgaaccaat
    16981 cccaatcatc cattgggagg acggaacagt cacagctgtc ccagaagaag agctaccatt
    17041 acggttgcct aagacaaaaa acatcaagcc aagcggtact ggagaatctc cattagcaaa
    17101 tatcgaggag tgggtcaatg tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac
    17161 gaatacaatg ccacaatggg caggaagctc atggtattac ctgcgttata tcgaccctca
    17221 taacaaaaaa gaactagcag attatgaaaa gttgaagcgt tggctaccag ttgacatcta
    17281 cattggtgga gcagaacatg cggtacttca tttactatat gcacgattct ggcataaatt
    17341 cttatacgat atcggtgttg ttcctacaaa agaaccattc caaaaactat acaatcaagg
    17401 aatgatctta ggcgaaaaca acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc
    17461 tgatgatgtg gtcgaaactt acggtgcaga tacactgcgc atgtacgaaa tgttcatggg
    17521 gccattagat gcttcgattg cttggagcga aaatggctta gaaggaagcc gtaaattctt
    17581 ggatcgtgta tggcgtttga tcgttgatga gaacaataaa atgcgtgacc gtatcactac
    17641 attgaatgat ggcaagcttg ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga
    17701 ctatgaaaat cttcatttca atacagcaat ctcccaattg atggtcttta tcaatgaagc
    17761 ctataaagtg gacgctctgc cttatgaata tatcgaagga tttgttcaac tactcgcacc
    17821 gattgctcct cacatgggtg aagaactatg ggcaatcctt ggaaatgatg gtggtatttc
    17881 ttacgcacca tggccaacat acgatgaagc agcacttgtt gaagacgaag tagaagttgt
    17941 tttccaagta aacggtaaag ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga
    18001 tgagctagaa aaagcagcat tagccaatga aatagtgcaa gaatatattg aaggcaaaac
    18061 agtcagaaaa gttattgcgg taccaaacaa gttagtcaat atcgttgcta attaattggc
    18121 tctttgtcaa taaggactga tgagttgtgc aaaatcaaat ctgggccaga atgaacttca
    18181 ttctgtctca gattttttgt tatttcaaat tgattaattg attgatcaaa aaggttttga
    18241 ttttcatgtt ctcaaacacg ttcaatgtct ttttcttctg aatggtcttg taagagatct
    18301 ctgtaatcat caaatttttg tctattaatc ttagtatttt ttgatgtata aactacctga
    18361 aattgagagt acataccaaa ttcataaatt ttttattagt gggactagtg attgtatgga
    18421 ttttgacgca taatgaatga agtatgagaa aaggagagac aaatggatca agaactattt
    18481 attatcgaag tattatcagc taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa
    18541 agaataatgt tcaagctttt aagcttagta tttttctctg gtttgctttt tttcggagct
    18601 gtatcgttcc tatatcgcca tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa
    18661 ttaaataatt tgtatcactt ttcgtgggga gttggcggaa taacaattgt tgtgcttatt
    18721 gtttttcttc tacttatttg gctccgttac catcaattgt cgcgtcattt cgatcaatgg
    18781 cttagtcaaa gagcacaaca gtttttacat aataaaccaa cttctcaaga tgatgactat
    18841 ctttattttg agaagacttc gacgagtcaa gcttttcgga tacaaaaaag tgattgccag
    18901 ttattgctga gatcacttga tgatttacct atctacttag gcgaaagcaa atcaaaattc
    18961 ggaatgaaca cattccatat ttttttacta gaaaacgaac ccagatggga aaaaagccag
    19021 tcttcgcctg gtggatacct gacaactaag atgagtacat tagtcactgg ttttttcctc
    19081 attcttttag ctggaacaat ctattatggg agatacactc agccaaaaat gtcttctcat
    19141 ataaatgctg cttctcacat gacaatgaac tcaactaacg atacgcatat acaaaagaca
    19201 aatgaagggt tgttagctga tcctaagcaa aaggtaaatt tgacaacaca aaagataaat
    19261 gatctcaaac ttgatacaga gacgcactct ctctatatga caacagatag tggtgctaat
    19321 tgggtatttg tgccgattga ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg
    19381 gggctgattc ctgaaggtta ttggatggac aacacatatg atatttccgc cgatttctca
    19441 tggtttatct attcttctgg ggatgatgta cgtctgctga cttcaagaga taatggtaaa
    19501 acatggcaaa cgtctattat cacccaatca gttcagccga tacgttatcg aaaagcggta
    19561 ttttatggca acgatggtct atttatctgt acatcagcca gtgggatgtc tgcagaaact
    19621 ttgtacattt acactactat ggatggcgga atcacttgga taaaaagtgg aagtacaatg
    19681 atcaatcagc cagtacaaaa tgtcagcttc gttacaactt ctttaggttt tgtttcgaca
    19741 cgtgaaagtt tgttttatac aaacaacgga ggacgctcat tcaaagaatc agttctgtcg
    19801 attccggaaa actatcagac aggggggata gatctttttc aatcaccaaa tgaagttact
    19861 caaataagcg cgaatacgtt agagacaaaa ttttatttgt tgaaaaaagg accaatcgat
    19921 gcagggaaaa tgtttgcctg cctcttccgt tcaactgata acggggaaac atggcaattc
    19981 gttcagcaac tatcgcaagt agaacaagga gattaaagaa gagagattgt gagcctgacg
    20041 ttcagcaccg agtcacaaga aacaaattca aaaaacagct tctcatattt gttgaatagt
    20101 gtaactcgtg attcggagtt gacaagagca acaagaagcg attttgaagt atagcttctc
    20161 gtattttaca agatcgtgtc ttattgccga taggttgtct cttgaacacc gtttattcgt
    20221 aaaaagggat tgtgacaagt cttttgtcac tacttaccga acgaaactga aggagctatc
    20281 caaaaagtat cattagtatt attctttgtg tttctagtgg caccactagt acatttaaaa
    20341 aagctatcga tcatggacta atcatacatg atcgatagct ttttagataa tgtttgttac
    20401 gctatctgaa attgactatt ataaagactg gcataaagcg ttggtgattg gagtagttca
    20461 gaatgtgttc ctttttcgac gatatcgcca ttcttcatta caaggatcat gtctgcattt
    20521 tcaatcgttg acaaacggtg tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc
    20581 attgcttgct gaatcaatgc ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa
    20641 ataacgacag gaggattcgc tagaatgact cgagcaattg tcaataattg ttgctgtcct
    20701 tgagataacg tgccgttttc gctagaaatg atcgtatcat atccgtctgg cagtgttcga
    20761 ataaagtgat cacattgtgc gatttcagcc gcttcgataa tttgttctct tgtggcatcc
    20821 attttcccgt aggcgatatt atcagctacc gttccttcaa acagccaggt attttgtaaa
    20881 accatcccaa aagaacgacg tagttctcca cgtgaaagct tggtaatatc aagaccgtcg
    20941 aattcgatct ttcctttatt cagttcataa aaacgcatca gcagattgac taaagtcgtt
    21001 tttcctgcac cagttggacc aacgatcgct accgtttgtt ttggctttac tgaaaaatcg
    21061 acttgattca tcaatatttt atctgatgtg taaccaaact gtacattttt gaaagctatt
    21121 tttcctttcg gttgttctaa aagtcttgca tctggaaggt ctggaatttc atctgtttca
    21181 tctaatatct caaatatcct atcgattgct gccattgcgg attggatcga gttgatcaca
    21241 taagaagcgg tagaaattgg ttcagaaatc tgattgatgt actgaagata agcttgtaag
    21301 aagccgatcg tcacaccacc tgatagaaca agcatagcac cgaataccgc acttatgatg
    21361 aaggcgagtt gattaatgaa acgaatggcc ggatagatag cacagttcat aaattgagca
    21421 cgtttaaaag cgttgtattg ctttttattt acttcgtgta tagcagcttc tgcatgagct
    21481 tgctgattga atgttttgac cactagatta ccagctaaga tttcttccat tcgattattt
    21541 aaaacaccca gttcatactg attctgttca gaaatctgtt tgtttttgtt cgcaatctta
    21601 gttgtaacaa ttgaactgcc aacgatcagc aataagacga gcaaagtaag cttgctttcg
    21661 atataaaaca gcatcagacc agcagcagct attgttacga cagaagtaaa aaattgattg
    21721 atacctgtca ataacacttg agaaagttga ttgagaccgg tagttgtccg actaatgatg
    21781 tcacctactt gatgattgtc aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt
    21841 tcttttcgca ccctcaatgt gatcttttcg cttaacgctg ccattgtccg ttcctgaata
    21901 aatgaagtga tgctgcttaa gactgaacag ccgatcagca ataagacagg gaacaacaat
    21961 gcttgtttga tatcactgaa agaaagctgt ccaatacctg tttttcttat ttctgataag
    22021 agatcatcga tcccgattcc catgatcaag ggcatggcta cgactaatag gttcccgaat
    22081 aaactgcata gaaacaatcc gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa
    22141 cgtatcaaag cacgcgtgtt caacgttttt ttcttttcca tcgtatccct tctttctata
    22201 ttccttgtga ttttgcaaac tcctgataag tttggcaatt agacagtagt tcttcatgag
    22261 taccttgtcc aacgattttt ccttcatcta aaacaatgat gttatctgct tgttggattg
    22321 tactgaggcg ttgagcaaca atcacgagag ttttctccga catgtgttta tgaagggctg
    22381 ctcttaatgc tgcatctgtt ttatagtcta aagcggagaa actatcatcg aatacataga
    22441 tctctgctgg tttgatcaac gctcgagcaa tacatatccg ctgtttctgg ccccctgaat
    22501 aattagaacc gccttgagca acaaagctgt ccaatccgtc aggaagggtg tccactagtt
    22561 cttctaattg agcgatcttg atcgctttag acaactcttc tgttgaggca tattcatttc
    22621 ccatctgcaa gttgcttaaa attgtcccgc tgaataagaa agccttctga gggacataac
    22681 tgatgtggga gcggatctgt tcttgagtca tttgagtaag aggaatacca ccaagggtta
    22741 cttttcctat cgtagggtca ctaagtctca agagaagttt cgccaaacta ctttttccag
    22801 atccggtccc gccaacgatc gctgttgttt ttcctttagg tattgtgaaa tcaatatctt
    22861 ctagaactgg atcagagatt tcagtatatt taaatgtgac atgttcaaaa gcagctgcat
    22921 ttgtctgatc aaaggttggt tcagctactg ttttgatcgt ctcttcctca atttcgatct
    22981 ctgcttgcag tatttcttct atccgtcgta atgaggcaaa cgatttaggg ataatgacca
    23041 ataccatagc tgcgatcatc aagtaagcaa gtgtcagcat agagtattcg actacagcag
    23101 tcacgacacc gatttgtaat gctccttctg ctacaagatt tccgccaaac cacaaaatag
    23161 aagcataaac gattcccatg agcaaaaaag caattggagt gacccaagca aatattcggt
    23221 tcactttgat catttgatta gcatagtcag caaagctctt attcgttcgc ttttcttcat
    23281 atgattgatt atcaaaggca cggatcatat taatcccagt aaagaattct ctcaatgtga
    23341 tggtgatccg atccattttt ggctggatac tcaaagataa aggtgcccct cgtttcatca
    23401 gtcgataaac aatccataca taaaaaacaa cagagatcaa tgtaacccat gttagtaata
    23461 gagaataacg aaacatcatg agaatggtga aaacgcaaat aaccggtgct ggtaagatca
    23521 tttggcaaaa taaaacaatc atttgctgga cattatcgac atcattcgtc attcttgtca
    23581 aaagagatcc agaactaaaa cgactgatat ccttcattga cagctgttgg aatttacgga
    23641 aatatttctc ccgcgtttgg aatccaaacc tagcggaagc caatgctgaa aagtaactag
    23701 aggcaactgc agcgattgtt cctagaaacg ctacaagcag catttcaact ccaatttttt
    23761 ttataactga ggcttcgcca cttgctatac ctgtgtcgat cagctttgct actaattttg
    23821 gtacacctaa tgtaccggcg atttctaaac agatcatcac aaaggtaagg agagcgagtc
    23881 ctttgttttt ctgtaagaat gtttttaaga tagacatatt attcctcctt ttttcctgat
    23941 acttttcgat tctatacctt caagtaactt gaaggtcaat agaaaaaaga ataaactgaa
    24001 aaagaggtga gaaaaaatga aaaaaatgta tacgattggc caagtatcgg aactatttga
    24061 tttgccaaaa tcaacgatcc gctattggga tgaacaagga ttaatccgtt caagtagaca
    24121 agaagagaat gattatcgat tgtttgatat cgatgatatt tttatgcttt atgatatcgt
    24181 tttttataga aaattagata taccgatcaa acagatgaag aatttatatg gaaaaacatt
    24241 gacggagtta tatgagacac ttgatgaaac agaaagaaga atccataaag aactggtggt
    24301 gatgaaacaa aaacaaaaag agataaggga gcaaaaaaaa cagttgaaat tgatgatcga
    24361 tacaaacgag gaagaatttc ctgtagaaga gatccctttt gactgtatga tctcaacgga
    24421 gtttgaagat attgtggaaa tcaaaaaatt tctacctaac tattcaagct ttgggatgat
    24481 gagtatgcca gcttccagtt cacagacgat gtatggattt tttatcgacc ctagtgaagt
    24541 acatttattt actcaagacg tgatttggga gaaaaaagat acggctgttt atcgtcgatt
    24601 cttattgaaa tccgagatga accatgcgga acgtaataat attttagaaa tcagagaaag
    24661 aatgtatgaa aaaggatgga aaacaggaga agtgatcggc cagtatctat tgacgaatac
    24721 ggatgaaaac aatatcagaa ctgaatatta tcatgcatgg atagaaatga aaaaatagga
    24781 aatatgtgtt taagataact cgaaaatgat ggttgtttta gttataaaga aaaattttct
    24841 ggttcgatta cgggtttaat gtgggggatt attagtcgtg gatagataga attttagttt
    24901 tttagaggaa atatgtcttt aaaaatggaa tggttgcaat tcttagcgat atatacgatg
    24961 taattgtcct cttaaaaaag tatggaaaaa taattgtatt gggtgttatg tataattcat
    25021 ggtgaactga gactaatgag aagaaaaatt catattgtta tgagtgagat tgtatcagat
    25081 gagaatgata aattaaatag gtgcataaaa gcattacact taaaatacat tgttgcttac
    25141 attattacaa tatgttaata aggcaaaaat aaatagatgg attgaataaa catatttttt
    25201 aatcaaatag tccctactgt gactttcctc agctatcggt gatactaccg atagcatttt
    25261 tttgcttata aaataattat aagtatttag agatttttct tctaacattc ttcaaacaag
    25321 aaaaatcaca aaggttattg ttatttttat atattctttt taagaatgat tgttttttta
    25381 tagaaatttt aaaaaataaa acacgttatt gatggatagt tagtttgtta tttggtaata
    25441 ttatagaagt tgactggtag tgatttattt ttcgtcgttt tataaaaatg ttattttttg
    25501 gaaaaattca caaatatgta acgaatgttt ttctggaatt tgctgtgtta aaaagcagta
    25561 tgactaatat aaatactatt gtcatttatg caatttttta tggatagtaa ttttagaggg
    25621 gaatcaatga aggaagaata gaagggaaaa atagttgcaa atacgccagt tagcaaaaat
    25681 agcaatacat cttcaagctt taaaattcga gagaatcatc ttggtagtgg aatcaactac
    25741 aacaaaagga ttaaaccaat taatagatag aattaccaat ggaaaaatag aaaaggtagt
    25801 tattctatac aaaagttgtt taattcgctt cggttatgaa cttagtgaaa ccctttgcaa
    25861 tatatggtac agaatataga aattattgac attacagaaa atgatgaaga tttaatacag
    25921 attgtcacta tttgtagata ccttttacaa ggaaaccgag ccaataaagc taagaagatg
    25981 attaaggagt tgatggaaga cgatacaagt taagaaagtg aaactacgcc caaataaaga
    26041 gcaaaaagag taattggacg tggaaaatgc aagaaatgaa ccatcgattc ggtggacagt
    26101 ttattagtaa tgacggtttg agaacatcca tgacgagaat gaaggaacat cctaaatgcg
    26161 tttagttgaa ccaagtgcca aataatatgg ccaaataagc gatcagttat cgatgaatcc
    26221 caagtattct aaactatata ttcattttga tgctaagcat tgatatattt ttttgggatt
    26281 gatgaaggtt aaccaataca gggactcact gatgaaattc tagagtctga ccttggtatc
    26341 aacgatttag tgattgtttc taatggaaaa gtataaaagt atataagtac attaacaaaa
    26401 taactattag ggttacgctc cagcttgtgc aaggcactgg caggaggaat cgtgaaatca
    26461 taattatggt taagccacac ggacaactaa aagtcataca aagctatcga atcaatcaac
    26521 agaagacaat cggcaatcat tagctttgtt tacagcttac attgcaacgc ttgagttgaa
    26581 ccgaaaatac gagggaggta acgcagccat tttgagttgg ggaatctttt tagaaaatta
    26641 tcgggtacct tgttgtttag tcaaaattat aagggggagt aatagtgagg aacaaatttc
    26701 ataaactgtt aagtatgttt ctagttatgc ttattgtgat caatcaattt gggaacataa
    26761 cggttctagc tgagtcttta gcagaacagc cagagcgttc gctgacgatc gaagttgatc
    26821 aagaggaggc tgctttgggt gagcagttcc agttgcgagt cagaggaaca ccagacctgc
    26881 taaatgcatt ggtcattgat aagagtgagg atttgattga aggggaagtg aagcaactca
    26941 atgattacga acgtctgatt acttattctt cccagcattc aggtaaatac gaattgaccg
    27001 caagaagcgg tgatattcaa tcaaatacgg tctcaataga aatcagtgta ccagaagaaa
    27061 gcacaagtga gtcttttaat gtaccagaag aaagcacaag tgaatctttt aatataccag
    27121 aagaaagctt aagtgaatct tttaatgaag ccagatcatc tgagccatct ataacgcagg
    27181 aatctcagat tgaaagacaa gaggagctct tgaattatga catcggcatc tctgctgagc
    27241 gccccacttt gccgagcagg catacacaaa cgttaaaggg atacattcaa ggaggcgctg
    27301 gcgatattct tgaagaatat ggggagatgg tcgtacgagt tcctagagca tcgattggct
    27361 taattgagtt cattagagtg gaggtcgctg atgattcacc tttaaagcca ctggcatttt
    27421 accaagaagg cacagacgtt gtttttccat ttacctttga ttatgaagga ttaaatgaag
    27481 ccgctcagtc gtatacattc agtatcacgt ttgaagttgc tttctttcaa tcaggcggta
    27541 ctgagccaaa taatgacttt caagtgagtc ttacttatgc tgagcgagca gcaaacacgg
    27601 aattttcaat tacgcctatt ccttcatcaa gacccatttt ttcgaaatta tactatggct
    27661 ctagagaaat cgacagccaa ggaaatcttg ggaatctgct gattgacggg caagacgtga
    27721 ccaacagtaa taaatttatt ttgcaggtaa attatgaagg atcacgaaaa gacggtgtag
    27781 tggttaccga tgtactaccg caaggaacaa ctttggcacc gaatccgact acatggagtt
    27841 ccactggaaa tagagaacct atttcaggtg gggttcggat cgcagaagta acgaatccag
    27901 gtgaagcaaa cgttagaact cattatgttt ccgaggaatt tgtggacaaa gtatctttta
    27961 ataaggaaac gaatacactt gttgtggact ttggtaatct agcagagggt caatcgtatt
    28021 ttattgaata tgctcttgaa gtgaccgatg tcgacttgtt caatgaagga agacaagagg
    28081 atgggttttc tcggaatcga gcgagtatga cctacaataa tcaggtaatg agccgagact
    28141 accgcttgag aatccctgaa agtaatcttc cggcaatctc tttaagaaaa agtgtggaca
    28201 aaaatgttat caatctcaat gaaaatgaac taacgtatac tctgcatgtc tcgatgtttt
    28261 ctggaacaag aaatacgctt gttattgaag atgttttgga agaaggcatg gaatttgtgt
    28321 catttctatc agatattccc tctttcattg atgccgaagt caataatgga atagttcgtt
    28381 tcagtgcgaa taatacgatt ggtggtccga caagttttac cctctctttt aaggtcaatg
    28441 tagaggcgta tgcggtcggc gatcaaattt taaactttgc aacgcttgtg aatagtgaca
    28501 atcgattgaa tacgagtact gtaagaacaa ggaaaatcga tgggcgtatt aaagtaatta
    28561 aaactgatga gaatggccaa aggctggcag gagcaaaatt tgaaatttta tcaagcgatt
    28621 cacaagtgat acaagaaggt ataacggcag aaaacggaga atttttaagt gaaccgcttc
    28681 ctgtaggtag ctatcaagtc cgagaaacag aagcaccgga agggtatctt ttagatgcga
    28741 cggtacatga tgtttttata aatgaatact ccatagaaga agtgacgtta accattgaaa
    28801 acatccttga tacgggtggt gttgaactaa ttaaacatgc tgaaggcagt ggtgaagtcc
    28861 ttcaaggagc tgtttttgag ttacagaacc gagaaggaga aacgctacaa accggtttaa
    28921 ctacaggaga agatggaaaa ctggcaattg acggtttagc accaggagca tatcagctgg
    28981 tagaaac
//
LOCUS       DAPBCF010000032        28142 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.032, whole genome shotgun sequence.
ACCESSION   DAPBCF010000032 DAPBCF010000000
VERSION     DAPBCF010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28142
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.032"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(32..1180)
                     /gene="nagA"
                     /locus_tag="RD508_001761"
     CDS             complement(32..1180)
                     /gene="nagA"
                     /locus_tag="RD508_001761"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDT7736322.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1256..2092)
                     /locus_tag="RD508_001762"
     CDS             complement(1256..2092)
                     /locus_tag="RD508_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7736323.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSQDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2276..3493)
                     /locus_tag="RD508_001763"
     CDS             complement(2276..3493)
                     /locus_tag="RD508_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7736324.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     ITSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3642..3821)
                     /locus_tag="RD508_001764"
     CDS             complement(3642..3821)
                     /locus_tag="RD508_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736325.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3876..3959
                     /locus_tag="RD508_001765"
     tRNA            3876..3959
                     /locus_tag="RD508_001765"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3910..3912,aa:Leu,seq:gag)
     gene            complement(4199..5569)
                     /locus_tag="RD508_001766"
     CDS             complement(4199..5569)
                     /locus_tag="RD508_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736326.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKYVF
                     EKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEI
                     NRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELI
                     FSLTTPGNALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFFLDMNILFLLLFFLI
                     FLLTYRKCQNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNLNNLF
                     TELGTKLSLFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFCSRLI
                     MGFSPTVWASGMRTYYILYVVIAILVLMAVKELMKSMSLQKNEFMQFGLTVLGICTFI
                     ITVINR"
     gene            complement(6284..6574)
                     /locus_tag="RD508_001767"
     CDS             complement(6284..6574)
                     /locus_tag="RD508_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736327.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(6782..6985)
                     /locus_tag="RD508_001768"
     CDS             complement(6782..6985)
                     /locus_tag="RD508_001768"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736328.1"
                     /translation="MNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLE
                     KAKDEVEDTADKSQQIVEEHLRK"
     gene            complement(7082..7474)
                     /locus_tag="RD508_001769"
     CDS             complement(7082..7474)
                     /locus_tag="RD508_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HDT7736329.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEIN"
     gene            7869..8492
                     /locus_tag="RD508_001770"
     CDS             7869..8492
                     /locus_tag="RD508_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7736330.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(8576..9298)
                     /locus_tag="RD508_001771"
     CDS             complement(8576..9298)
                     /locus_tag="RD508_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDT7736331.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQSYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKTVPIDHLLIETDGLHAAEWALGGIFSEKYYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(9288..10025)
                     /locus_tag="RD508_001772"
     CDS             complement(9288..10025)
                     /locus_tag="RD508_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7736332.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYRNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            complement(10037..11029)
                     /locus_tag="RD508_001773"
     CDS             complement(10037..11029)
                     /locus_tag="RD508_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7736333.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQETKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDITYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDNPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            complement(11044..11787)
                     /locus_tag="RD508_001774"
     CDS             complement(11044..11787)
                     /locus_tag="RD508_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7736334.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     regulatory      complement(11861..11965)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12028..13350)
                     /locus_tag="RD508_001775"
     CDS             complement(12028..13350)
                     /locus_tag="RD508_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7736335.1"
                     /translation="MKTYDAIVIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYFVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANVVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRNPPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     gene            complement(13337..14302)
                     /locus_tag="RD508_001776"
     CDS             complement(13337..14302)
                     /locus_tag="RD508_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7736336.1"
                     /translation="MTKLIEFKHVQKKYDRKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFNEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            complement(14299..15837)
                     /locus_tag="RD508_001777"
     CDS             complement(14299..15837)
                     /locus_tag="RD508_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HDT7736337.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKVLNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            complement(16253..16540)
                     /locus_tag="RD508_001778"
     CDS             complement(16253..16540)
                     /locus_tag="RD508_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736338.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            16674..17342
                     /locus_tag="RD508_001779"
     CDS             16674..17342
                     /locus_tag="RD508_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7736339.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(17628..18368)
                     /locus_tag="RD508_001780"
     CDS             complement(17628..18368)
                     /locus_tag="RD508_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736340.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKGNLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKMLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(18498..19445)
                     /locus_tag="RD508_001781"
     CDS             complement(18498..19445)
                     /locus_tag="RD508_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7736341.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(19574..20338)
                     /locus_tag="RD508_001782"
     CDS             complement(19574..20338)
                     /locus_tag="RD508_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDT7736342.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRGSEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(20342..20731)
                     /locus_tag="RD508_001783"
     CDS             complement(20342..20731)
                     /locus_tag="RD508_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736343.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            20865..21407
                     /locus_tag="RD508_001784"
     CDS             20865..21407
                     /locus_tag="RD508_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HDT7736344.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            21555..22187
                     /locus_tag="RD508_001785"
     CDS             21555..22187
                     /locus_tag="RD508_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736345.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(22321..22446)
                     /locus_tag="RD508_001786"
     CDS             complement(22321..22446)
                     /locus_tag="RD508_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7736346.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYSILWEELAA"
     gene            complement(22580..23476)
                     /locus_tag="RD508_001787"
     CDS             complement(22580..23476)
                     /locus_tag="RD508_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HDT7736347.1"
                     /translation="MNYYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKK
                     EFSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLS
                     VDEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRATAGNEKYRFITLSSIEHF
                     PLTLANYFFVQKNQLPVTKAFKELAELIGDVNEAYFFDQIEVIVDRIRKNKYKNRRPS
                     IFHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEETAFLKRQIFSELS
                     KKFIPHAFSYIKEYRTVLVSKT"
     gene            complement(23658..24584)
                     /locus_tag="RD508_001788"
     CDS             complement(23658..24584)
                     /locus_tag="RD508_001788"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HDT7736348.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(24669..25430)
                     /gene="pflA"
                     /locus_tag="RD508_001789"
     CDS             complement(24669..25430)
                     /gene="pflA"
                     /locus_tag="RD508_001789"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HDT7736349.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGNKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(25674..27905)
                     /gene="pflB"
                     /locus_tag="RD508_001790"
     CDS             complement(25674..27905)
                     /gene="pflB"
                     /locus_tag="RD508_001790"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDT7736350.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
BASE COUNT         8219 a         5698 c         4628 g         9597 t
ORIGIN      
        1 aagtttagtt ttaaggttaa cttaaattat attatgcgtg gaaacgttcc acgccatcta
       61 gataagttgc ttccaatgtc atatcagggt tcaatacgat aaagtctgca tcgcgtcctt
      121 gagcgatttt tccacatgta tcatcgattt tacagctgat tgctggaatc agactagcca
      181 tcatgactgc ttgttctggt gttgctaatc cccaatctac aacattttta attgcttctt
      241 tcaatttcaa tatacttcca gctaagttgc cagattctag acgtgctgtt ccttctttta
      301 ctactactgg aaattcgcct aaattgtaat ttccatcagg catcccaccg gccatcatac
      361 agtctgtaat taatgcgaca tgatcatgtc ctgctttttc cattaggatt cccgcagcat
      421 ttggatgtac atgatggcca tcacaaatca attcagaaaa gacatgttct aaagataata
      481 acgcacccac catacctggt tcgcgatgat tcaatccacg cataccattg aaagcatgga
      541 caaatacact ggcgccagct tcaacagctt tttgcgcttc ttctagcgta gcgttactgt
      601 gacctagaga aacaactact ccttcttcag tcacttgttt gacaaactct tctacacctt
      661 gacgttccgg tgctaaagca atttttttga ttaaaccgcc tgaagcttct tgccattcat
      721 ggaaagtatc caaatcagga tccccgaaat aacttgggtt ttgtgcccct ttgtgttctt
      781 ctgtgaagaa aggaccttca aaatagattc ctttgatttt agctcctggt gcttcctgat
      841 acattttgcc gattgtctca gctacatctt ttaaacgttc tttgcttgac gtcaatgttg
      901 ttggtaaaaa tgaagtcact ccacaagata acagaccttc agacatcact ttgatgcctt
      961 ctgcatcatt atccattaca tcatgattca tatagccgtg aatatgtgta tctaccaaac
     1021 caggagcaat ccatttgccg ctttggtcaa tgatgttgac ttctccctca ggtagttctt
     1081 tggtgtattc accaaaaagt ccatcggtaa tttcaagata gcctgcatgt ttgacacctg
     1141 acgctaaaaa gaatttgtca gcatagataa aagttctcat tctattctct ccctttgttt
     1201 ttctacctct aaagtactct tatttagaga agaagtcaag aatggtctac accatttaca
     1261 aattttttga aatttgtttc acagcttgtg ctaagccttc atagaatgct gctctttctg
     1321 gttcttcttt acgcttgtat attaagcttt taagcacaaa taaatcattg aggtaatagt
     1381 agctattctt ctcttgagcc caatagattc cttgattcac ctgttctaac gcttcgtcga
     1441 tttcattttg atggaataag aaatttccat aattataaaa aatttgcgaa aattcacttt
     1501 ttgatcgttc gtcagctgat tggtgcaaca gttgaatgct tcgactcaaa taatagcgtg
     1561 cttcagccgt ttttcctgca acaccatata tttttccaat gcaactgatc agttgtattt
     1621 ctgtgtcaga aacatggatt ctttcttttt ggctagagta gcttaatgct tctttcaaat
     1681 aataaaggga ctgagagata ttttgacgca acgtgaattc gcaaacaccg agataataat
     1741 aatagcgttg aaagtcagtt gcttgataca gattttcaga aatatcagaa gattttagta
     1801 cttgttctaa cttccgataa tcacgttttt ggaaacaact atccaacagt tcaaataatt
     1861 tatcgtttgt ccgagtagtt tttcgagaga gattcatcac atgatcaatc gttaccccta
     1921 gccgttgaca aatctgcatc atcaccaata cattcggcag ttcctcatta ttttcgatcc
     1981 gacttaatac actttgtgaa caaatatctt gcgaaagcat tttttgcgtc attttttgtt
     2041 cttttcgaat ctctttaatg atcgtgccaa aggactcgat taacgtttcc ataagtatcc
     2101 tccccaaaat atgcgtattc gcattctatt cgtattttac tttaggaagt cgcaaacttc
     2161 aagaaaagac ttgcaactaa ataatatact ttagttattt aagaaaactc cactagaaag
     2221 agagcctcag tgtgtttgtc tgtggccctc ctactgaaaa atttggtttt taaaatcatt
     2281 tttggcgata ggttgctagg aattctctca ttttcttagc tgtttgtttc aaatcatcca
     2341 ttttaggaag ataaacgatt cgaaaatgat ctggctggtt ccaattaaat ccaccaccat
     2401 gtacaagtag aatatgatgt tcatgtaaaa agtccaaaac gaatttttca tcatccaaaa
     2461 tattgaatcg ctttgtatca atttttggga atatataaaa agcagctttt ggttttacgg
     2521 ctgaaagacc aggaatatca ttgattgcat tatagatata ttctctttgt tcatagatcc
     2581 ttccgcctgg caggagcagc tcatcgacac tttgataacc gcctagcgcg gtttggataa
     2641 tttgctgaga caatacattg gaacacaaac gcatggagga caacatattc agcccttcta
     2701 tatagccttt aacgtgtgac ttatctccac ttaggaccat ccagcctact cgaaatcctg
     2761 ctacacgatg agatttggat agaccattca gcgtaacaac gaacaaatca ggcgctaatg
     2821 tagcaatcgg aatatgttct agaccatcca tcactaagcg atcatagatt tcgtcggaat
     2881 aaataatcag gttattttgt cgagctactt caacgatttc ttctaataat tcttttggat
     2941 aaagtgcccc agtaggatta ttaggattaa tgataacaat agcttttgtc cgactcgtta
     3001 tttttgatgt gatatcatca atatcaggat accattctgc ctcttcatcg caaatataat
     3061 gaacaggtgt gcctccagct aatgcaatag aagccgtcca caacggatag tccggcattg
     3121 gaaccagtac ttcatctcca ttgtccagca acccctgcat acacatcgtg atcaattcgc
     3181 tcactccgtt gccggtgtag atatcattga tcgtcacatt cggaaaatgt ttcagttggc
     3241 aatattgctc aattgctttt ctagcagaaa agatcccctt ggaatctgag tagccttctg
     3301 agtcacgggc attcatgatc aaatcacgaa tgacttcgtt tggtgcttca aatccaaaag
     3361 gtgcgggatt tcccgtgttc aattttaaaa tactaatgcc ctcttcttgc atccgctccg
     3421 cttcttctag aacgggaccg cgaacatcgt aactgacacc ttctaatttg ttggattttt
     3481 caaattctct catcacttag ccaatccctc atttcaaaaa gttagaactt tccaaatttt
     3541 ttgttattta ctatttcaat atcatactcc atcctagaaa attttgccac ttatttagga
     3601 aaaacgtaag tattaaaaaa acacaaacaa gcgttaagaa cttaattgtc atgatagtca
     3661 ttccatagat tcgctgccca atccattgca attccacaaa tgattcctag cataaaacca
     3721 agcaaaaaac gtccgaatgc aagtccaatc aatacaccta agatcattcc cagtcctgaa
     3781 aattctccgt catatttctc catcttaata agtcctccca tttttgagct tgacaactat
     3841 gtaaaacctc gctatcatta ttgtgttatt attacgcaga tgtgttggaa ttggcagaca
     3901 agcatgattg agggtcatgt gagcgttagc tcgtgtgggt tcgagtccca tcatctgcac
     3961 tacaactcgt gaagttaatt ttgcttcacg agtttttttg tttgaacgtt tctttatgcc
     4021 attatataca tatcactgta tcctttacaa aaagaacgta caatcatgta aacagcctga
     4081 ggtgagtata tgaaggtcgg aaacaagcta ctcgtagaaa cttgcaagtg ttaaaacaat
     4141 taatcgaaaa acgagtaaaa tccctcacct aatactagag cgagggattt tttgtatatt
     4201 atctgtttat caccgttatt ataaaggtac aaataccaag cacggttaat ccaaattgca
     4261 taaattcatt tttttgtaaa ctcatgcttt tcattagctc tttaactgcc attagtacta
     4321 agatggcgat aacaacataa agtatatagt acgtccgcat tccggaagcc catactgtgg
     4381 gagaaaatcc cataattaac cttgaacaaa atcccattat catcaaaata actaaaaaaa
     4441 tagaagtttt cttattgtca aaacttaaat aaattccaac aattaaacat agtaataatg
     4501 ccaagactac taaagtagct atccaagtac ctggataaaa aagtgacagt ttcgttccta
     4561 actctgtaaa gagattattc aggttactac tactccaaat cattgccctt ttatttccat
     4621 tgacgtaagt aaagctttga cccattgtat taccaaaata aataatcagg tttaagaaaa
     4681 acggtaatgc agtcaatata cgcacataat agttttgaca tttcctatat gttagaagga
     4741 aaattaagaa aaatagcaat aaaaataaga tattcatgtc taaaaaaaac ggctttccaa
     4801 atgatgaaat acctaaatct aacttattaa gaaagttgaa atttttatat tcaggaaacc
     4861 atttattaat ttcatgtgca gcacgtaatg cattccctgg agttgtcaaa gagaaaatta
     4921 attctgctaa gcttattatt gaaaatactg ataacttata attatatcgt ccattgacaa
     4981 tcaaatataa actaactata cttgttagaa caaaaaaaca ggcgttgact tgttcttgat
     5041 tagttaaaaa tatcaataaa ggaatactta cccaatatat ttttctattt atttcttctc
     5101 ctcttaagag ttgaaaaaac ggataaaaag ttagtaaact aaatgctact ggccactgat
     5161 agttcaaggt ggttgctctc caaccggttt cccccattac tgtcaatggt attaaacagt
     5221 atatagagca aaccaataat aaatttttaa catttatttt ctcaaaaaca tacttgcaaa
     5281 gtaatactac aattcctaac ataatcgtag aatttaataa tttccatagc ataaagtgtt
     5341 tagaaaagaa cattaagaat agttctataa taattcttga actccatgtc ttataatgtt
     5401 ctatcgaagc acccaaatag ccaagttcat ctaatctact tgcataaact acgtcatccg
     5461 ctctcatagt cggcatatac atattaaaga gtaaaaagat accccaaatc cctattagta
     5521 acaagatcag ttctttgtta ttcgttattt ttctattatg tttgttcatt tttatactcc
     5581 ttcttatatt tcctaataga gtataacata gctttaagca ttacttaaag ataacttaaa
     5641 agttatcttt taaatactta attgttaaat accttatttg atgcaaaaga aatctacgat
     5701 agtcaacaaa aaaaattttc attatatcca gaaaaatttt tcttagttaa ggacctatgg
     5761 attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca tattgctttt
     5821 aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt aggtttaact
     5881 gtcgaaccag gacgttctcg tgtgaaagac gaggcttctt caatttactt ttacgactat
     5941 gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa atcctacaat
     6001 tccactacct gagactagta atgactagtc tctttttatg gcctctgatc cccccattga
     6061 gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat ccctcaaatg
     6121 agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta tatatagatt
     6181 gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgaa tccatctttc
     6241 caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt attctttcat
     6301 cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca attttgggtt
     6361 tccctaacac atgataggat ctcacaacaa attgctttct attattataa taacctgtaa
     6421 cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg gaagcaatca
     6481 aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact tgcaaagtac
     6541 ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata ccattatacg
     6601 aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt tttgtctatt
     6661 acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta ctaaaaaaaa
     6721 gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt gttaagaaag
     6781 attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta tcttccactt
     6841 catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt tcagcagttg
     6901 cttcgtctaa tttcttttgt gtatctgtta actgagtttc tacatttgtt ttttcttgtg
     6961 tcagtgttgc gatttgttga ttcaaaccat ttacagtatt ttgtaattct gaaagttttg
     7021 cttgtgcttc ttgtagtctt gctgtccaat ctgcattcag atgattgatt tcatcatttt
     7081 tttagttgat ctcatctagt ttgacattga tttcattttg cttgctttgt agttgtgcat
     7141 ccttgctgac taattgactt tctaagtttt gtttttctgc tgccgattga tttttttggt
     7201 tttctaattc atttactttt gtttggtatt cttggacatc tgcctttgaa tcttgcaatg
     7261 tctgttcttt ttgtgctagt cgagcggtaa gatctgtaat cgcttgctct ttatctgtca
     7321 atgtatgatc aagctgtgtc agattctcat tgattgtatc aatatctgtc tctccacccc
     7381 acaaaataat ttcatttgcg taccgcgtgc ctgtgtagcc aattagacat agaaatgcaa
     7441 cgacaatccc accagtaata aatttctttt tcatttgcat agctccttaa tccaatactt
     7501 ttacatacta aaagtaagtg atctcaaaca caatgtcaag cgtttttaaa ttacatatgt
     7561 aattttaata taaatactat caaatactca tttaatcctc cttttttatc tatttaaaaa
     7621 atctttttta tagagaaaaa tgcaggttaa tactttctta aataaatatt tatggtgaac
     7681 aaaaacaaaa aagcaagttt tattaaacgt aacccttttc atttcataga ttactgtatt
     7741 tattacaaaa aacgtggatt tgtcataaat tgtcatgctt cttttaccta tgaagtattt
     7801 tcacgtgtta aagtattcct cgttgaacac aacaaataaa actttttaac gaataaagga
     7861 gatttttcat gacatcactt aaaactttac tttttggaac aactttggct gccggcgctg
     7921 cattcttcat gggaacgact gctcatgcgg acgaagctta taccgttcaa tcaggtgata
     7981 ctctatcaac gatttctcaa aaatacgttg gtgataactc cttgatcaat gccattgcag
     8041 aatcaaattc aatttctgat attaacctga tttactcagg acaacaatta acaatcccaa
     8101 cagaaggctc tgcacaagca gctgctgaac ctcaagcagc cgttcaagaa gcaccagtcc
     8161 aagctgaaca acctgttgta caagaaacgg ttcaaacgga aacacaagca gcgcctgttg
     8221 ctgaaacaca acctgctcct gctgtaacag aaactgctgc tactccagca agtacaagct
     8281 ctgcaaaaga atggatcgca caaaaagaat caagcggttc ttacacagca acgaacggac
     8341 gttacatcgg ccgttaccaa ttagattctt cttacttaaa tggtgactac tctgctgcaa
     8401 accaagaaag agtagcagaa caatatgtta cttcacgtta tggttcttgg gaagcggcga
     8461 aagcattctg ggaagcaaac ggttggtact aagattcatt tattaatcga acggtttact
     8521 tttatacaaa gaaagccaaa aagaggtgtg acacaactag tgtcacacct cctttttatt
     8581 tacctaatct aatgaaacgt tccaagtttt gataagtatt tttcttaact tcttcaactg
     8641 atagctcttt gatctcagcg attgtcttta actgttcttc aagcagtgag acataatatt
     8701 tttctgaaaa aatcccccct aaagcccact ctgctgcatg tagtccatcc gtttcaataa
     8761 gtaagtggtc gattgggact gttttagcta gttgccagac tgctgggttc tttttcaaat
     8821 caagaccaat gctgaaataa cagcctaaat caatatagtc ttgttgatag tccaaagaag
     8881 aataccaatg aatcaaatag tgattagggt aagattggat ataatttaag atctcttttt
     8941 cgcatccttt tgtatgcagt acaacaggtt tctcatttat ggctgcaaaa gcaagctgtc
     9001 gctcaaatac ttttttttgt gtagtcatcg gtacattcgt ccaaatatta tctaacccta
     9061 tttcaccgat gatccttgct tttttcaaaa aaggctcaac ttgttcaaac gtatagctat
     9121 ctgctttcca aggatggata ccgtaactta aggcttgagt cttacttgct gcaagctgtc
     9181 tgttttcctt ccattcttct ggcgaatcac aattgatgat cgtcaaaatc gtgtgttcct
     9241 gctgaaggag tgctaaactc tgactcccat ctaaatgaca atgagcatca cttaacatct
     9301 aattcacctg ccaataactg ataaatcgtt tgcttcaact ctgattgctg cagtagccat
     9361 tcacgtgacc gtcgtttttc aggcacttga atctcagcaa tcacatgtgc cggacgggcg
     9421 gaaagcacaa gaatcctgtc tgataaataa attgcttctt cgatatcatg cgtcacaagt
     9481 aaagtagtcc gctttgcttt tttaggcagc ttcaacatcc agtcttgcat ctgccctctg
     9541 gtcatagcat ctaacgctcc aaatggttca tcaagaagca agtaagaaga aggattcatg
     9601 attgttcgta acaaggccgt tcgctgcttc atcccgccag ataattgttc cggcaaaaaa
     9661 tgttcatatc cgtttaaccc aaagatatcc agataatccc ttacttgttc ttcattgatt
     9721 gttagatgat tgattttttg atataacgta acgtttcgat agacgctcag ccaaggaagt
     9781 aacatatctt cttgcggcat ataactaaat gctgtatgga gaccagttac tttttgatcg
     9841 tctactttga tcgttccaga agtcataggc tggactcctg ttaaagtttt cagcaatgtt
     9901 gacttaccgg ctccgcttgg cgcgacaatc gatgtaaagg tatctttagg gatagtgaaa
     9961 tggatgtctt ctaatatttt caggttttca atgactacat tcaagtggct gatttggatt
    10021 gacatatcta tcactcctat tttataaact gattagtgaa tagttcttgc gaaggtacat
    10081 cttgcttgat caatccgttt tcctgcataa aagctgtata attgcgccaa actttttctt
    10141 ccatcaatcc ccaattctca ggattatccg tataattttt tgacaagaat gcttgtgatt
    10201 cttctaaaaa cgtccgatca ttttcttttg catatttttg caacagttta gcactgtcat
    10261 ttggatcctt aatagcttcc tgatagcctt ttttcgtggc atccataaaa gactgtacca
    10321 attctggatc acttttgatc agttgatcat tcgtaataat taccggagta tagtaatcta
    10381 accgttcatc taattctttc aatgggatat agtttagttc aatacccgct tcttttgctt
    10441 tgatcatatc ccaaccttca aagtaccatt ggatatctga ggattttcct aagctttctg
    10501 gcccttctcc attgcttcct accattgtca gttttgaaaa gtccccgccg tctttttcca
    10561 tcacagcttt taagacagct tcttcacttg gactttgcca acctgcatat gtttttcctt
    10621 caaaatcttt tggtgaatgg atgttactgt ctgatagggt agcgaatcca gaagtattat
    10681 gtttgatcac tgtagcaatt gctttgactg gtatattctg tccatctgcg tgagcataag
    10741 tgatatcttc ttgataactt acaccaaatt gtgctttgtc cgcacctact agaccaatac
    10801 ttgtcgaatt atctcctggt tcgatgattt ggacatttaa accagcctct ttataatagc
    10861 ctttttcttt tgctaggtag atgccagtat gattagtatt cggtacataa tccaaaacaa
    10921 gtgtcacttt tttcaaatcc tttgtttctt gtttgctact tgtttctttt gcagtgccac
    10981 aagcggataa aagcaacagt agcggtaata aaagccataa ttttttcatt tgatcccctt
    11041 ctcttaaaaa atataaagca tacgataata cccttttttc aataatgaac aagcgccatt
    11101 cagcaataaa ctcaatagaa tgacacaaat gatcgcagca aaaactttat cgatctggta
    11161 gctgtttttt acgcgtatca tgtaataccc taagcctgct tgagcactta gccattctcc
    11221 aacgactgct ccgctgacac aataagtagc agccactttt aaaccggaaa agaagccgga
    11281 taaacccgct ggtattttat atattcgata aatcttccct gtatctgccc ccatcgtttt
    11341 caaaaagatg atttgctctt ttgatacttt cctcaatgta tccgaaaaag aaactacgat
    11401 cggaaaatag cttatcaaga caacaaggat cacttttgga agcataccga aaccaaacca
    11461 tagggtaagt aatggcccta acaccatgat tggcaacatt tgtgaaatca ctagtaacgg
    11521 ataaaaagac atttctaaaa acttccaata atccattgcc aaggcagtaa taaaagaaag
    11581 aacgctagct attaccaaac caagcactgc ttcatttaat gtcgtgacag aatgggaaag
    11641 taatacttgt gcatctgccg ctaatgcaga aaatacagca gcaggtccgg gtaaaataaa
    11701 ggcaggtatt ttccaaacta tgacaacaat ctgccaaata attaaaatga atgccatact
    11761 gactgctgga taaagatttt tcttcatttt gttacctcct ttcttctaat atgaataaca
    11821 aaaaacgctt gaaatgggca cgacatagta acccgcttca agcgtctgct atgtttctcc
    11881 cttcaccagt attaactgac aggttcaatg ggtctaagtt cacaacttac tctcatgtcg
    11941 tctacgacat ccccagaaac aggtattcat tttttaaagt gtagcacaag aaggaaaaag
    12001 caacaagcgc tttagttatc atgctgatta tttcaataaa taggagagat cacttgccaa
    12061 tgtcggatac cccatgatat agctatccaa ctctttttta gtcaattttt gattgatgac
    12121 tagtgtcaaa tcatcgatca attcgtctgc ttgctcgcta atcactgcag caccaatcaa
    12181 ataattttgc tggtcaaagg tcaattcagc cttagcaact ggttcattga cacgatgata
    12241 ggtgaaccaa ctggtaagat ccatctctac cacttgatct gacgaagaag cgtgactttt
    12301 tgtaacacct acttcagcaa gtttaggact ggcgtagacg atcgtaggta taatcggata
    12361 tttgataggt tcgcttgttg catccgttat ccgcttagct acataatttc cttcaaaagt
    12421 ggcgactggt gtcaatttgg gggggttcct tgaaacaata tctccacacg caaaaatttt
    12481 tggattgctc gtttgcagat aatcattgac tgcaattccg tgtttatcaa agacgacatt
    12541 cgcttgctca agtgctaaag attctgtatt cggctgtctc ccagtcgcac aaaaaatcat
    12601 atctgctact aattccgtct cttttccgac taaacgatag cgagtacctt ctgaaatgat
    12661 cttttgggtt tcaacaccaa aagcaaactg aatgccagat gcttccattt gatggacggc
    12721 ttcctctacc aaagacgcct caaattcttt taatggccgt tgattatgat ggacaatggt
    12781 tactttgctc cctgcagcat tggcaatcgt agctagctca aaagcaatat aaccaccacc
    12841 gataaaaatg atttctttag gcagtacagg caatgataaa aagtctgcac tagttttcaa
    12901 gtattccttt ccctccactg gtaagatcgt aggtctttgc ccggttgcca aaacaaagta
    12961 atccgcatgg aagacttctt cgttgacttc aatagatgaa tcatccaaaa aacgagcggt
    13021 tcctgaaaga tgatcgattt cagcttctgc taattgtttt tttcggcttt ctgggactgg
    13081 atccgtaaat gttcgtttga atttttgaag ttcttcccag ttggcagttg ggatctcgtt
    13141 aaaacctttt ccactcaatt gttttacccg attacgtgcc tctactgcac ttaacaagac
    13201 ttttttagga tcacatccac ggttaggaca agtcccgccc catagatctt cttcgaccac
    13261 tagtactgtt ttacctgctt ctttcaatcc ataagcagca cttaagccgc tcacacctga
    13321 accgatgacg attgcatcat atgttttcat ttccttcctc ctctcgactt aaaaaagcaa
    13381 agatttcttt acttgtcagc gacccaatac ttctttgctt ttctactatc acaatgcttg
    13441 gatacaccga aagaagcgaa tatacttctt tcataggcgt atcaaagcaa acttgttgac
    13501 gagcattttc tggtatttca tttaagaaat atccattgac gactaaatct tctactcgcc
    13561 actctttcgt ctgtttcggt tcattaaaga aatgccgaac gtagtcgttt ttaggattca
    13621 tcaataactg ctctggtgtg tcacattgga taatttctcc atccttcata aatgcaatac
    13681 gatcacctaa cttgattgct tcttccatat tgtgcgtaac gaaaacgatg gtcgtgccca
    13741 attcttcgtg taaggacaaa accaattctt gtaatgagtt tcttgaaatc ggatctaatg
    13801 cgctaaatgg ctcgtccatc aaaatcacat ctgggcttgc agcaatagct cggatgatcc
    13861 cgatccgttg ctgttctcct ccagacaact ctctaggcat acgatctcga taaatatcag
    13921 gagataagcc aactttttga agaagttcat ctacacggtc tgctcttttc tgcttttccc
    13981 aacctaacat ttcagggatg acttcaatat tttgcttgac tgtcatggtc gggaacaaag
    14041 cgatttgctg cagcacatat cccatattcc accgcatttt ctgcagatta tattcattta
    14101 acgattttcc tttgaagtag atgtctcctg ctgatggttt agataatcca ttgatcattt
    14161 tcaaagtagt tgtttttcca ctaccggaag gaccaaccaa aacaaagatt tctccttttt
    14221 tgattgccag atttaggtca tcgatgacat actttctatc atactttttt tgcacatgtt
    14281 tgaactcgat taatttagtc actgatcttc ctcctttact aatccttcat ttttcaggaa
    14341 gattcgtgct acttctgtcg gctttttctt ttcgacattg acttggtaat tcatatcaat
    14401 catttgatcc tctgttattt ttccgcttaa tttattcagt actttaacga tttcaggatg
    14461 ttctttagca aaatcttttt tcatcagcgg tgcgccttga taagctggga ataaccctcg
    14521 atcatcttct agagtcacta gatcgtactc cttgagctgg ctatctgtgg aataggcatc
    14581 cacaatattg acatctccat tattgattgc ttggtaacgc aaacttggct ccatgctttg
    14641 tacacttgaa aaattcaagc catatgcttc ttggattcct ttatatccat ctgaacgatc
    14701 aataaattcc agtgtgaatc ccgctttgat ctgatcagag atagctgcca aatcggaaat
    14761 ctttttaagt tgatgttcgt tcgcaaaaga tctcttgact gccaaggcat acgtattttg
    14821 gtaagccatt ggttttaata atgtcatatc gaattgctta ttcaataatt cttctgcttc
    14881 gtcatatgtt ttttcttttg tcaaatcagc acttttcatt gcttcaggta ccttcaccaa
    14941 gctttctagg acagtacctg tgaactcagg atagatatcg atttgacctt gatccagtgc
    15001 attgaacaaa aaactcgtct tgccaaaatt cggttttaat tcaacttctg tttttgtgtt
    15061 gtcttcaatc aattctttat acatttggat caggatttca ggttccgctc ctaattttcc
    15121 agcaatcgtg atggtttcat ttttaaacaa ggcagactga tataaagaaa cgccgccaaa
    15181 taaacacacc actgctgcta aagtaatgat ggaatatcga ggtttcttat gctgcaacca
    15241 gcgaatcagt ccgctgaata taattgcaag caaggcagaa ctgatcgcac caatcaatgt
    15301 caaaacaggt gtatttcggt caatacctaa caaaataaat gtccctaatc cacctgctcc
    15361 gatcaatgct gccaaagtag ccgtaccgat gattaaaact aaggcagttc ggatacctga
    15421 gataatgaca ggtaatgcga tgggaagctc tactttcagc aagcgtctca ttctggacat
    15481 accaaatgct accgctgctt cttcaataga cgggtcaatt tcagctagac caatatacgt
    15541 gttttggaaa atcggaagca aagcgtaaat aacaagtgca atcaatgctg gaacagttcc
    15601 gatccctaca aatgggataa gtaaacctaa taaggcaagt gaaggaatcg tttggagcac
    15661 acccgtgatc tgcaataaga cttctgccat ttttttatga ttggctgccc aaatcgctaa
    15721 aggaatagca atcagtgctg caatcagcaa agaaatgaga gaaatggaca gatgttgaaa
    15781 tgcagcttcc agcaactcgc cttttctttc acttaatgtt tgtataaaat tattcatgcg
    15841 accttccttt ctgttattct ttaagtataa acatttcttt cctttttccc aactaacttg
    15901 tcttgcctta accttacagc acgaacaaaa aaaaagaaaa aaatacctct aaatatgctg
    15961 acaaaaaaga atccaagcaa caaagtcgga tcaacttttt ggttctcgtt ttttcactac
    16021 gaataccata aaaatctata cgaaattgtc acttggaatc agctatatct tttttacaca
    16081 cacaactttt attttaataa aaagaaacag ccaataaagt agaaatctcg tgggggagaa
    16141 cacctttatt ggcctgttca acgaatatta tactgtatca tgacactttt ttgccaaaaa
    16201 tgtaaaaaac ggttgttttg acatcataaa cgtcttgttt tcttattttt acttatatca
    16261 ccactttatt ttctatctct ttcactccat aaagcggaat gagttcttct tttgactgat
    16321 aataaacagc tttctcacgg ttcttcatca aaaaaagaaa gatgtctttc atagcaagtg
    16381 gtgctttgcc gtgttcaaat aaaaagataa attgatttgc tttatttatc tggaccattg
    16441 tcacaggcac cagtttttgt tcttgagcca aaaaaactcc ttgatactct gtttttttgg
    16501 gtgattttgt aagaattgtc aataagtctg ctgctcgcat ttttccactc cttatttgat
    16561 aaataaaaag aaacagccaa aaataatttt ttttcatttt cctcttgaag taagagtata
    16621 agtcagtata ataaagaagt tgctgaaaat tttcaaaaga aaagaggcta gaaatgaaaa
    16681 aattaaattt atttacagaa ttgtgcggaa tcattttagg cgcaggaatc tacggattag
    16741 ctgtgacagg aatcaatatt ccatctaagc tggcagatgg tggggttact ggtattgctt
    16801 tgctcttgca taatcttttt ggattcgctc cttctgtcac ttcactgctt tttaatttac
    16861 ctttattgct tatctcattg tttctttttg gaaaacacgc ttttctccgg acgatcgtcg
    16921 gaacatttgc gctagttttc tttttacatt tatgggagag ccttcatata cattttgctg
    16981 tagatagtct actgatcaat agtttgatga caggtattct ttctggcatt ggttgcggtc
    17041 tcgtctttcg attcggcgga agcacaggcg gaacagatat catttatcaa gccattgaaa
    17101 aatattttca tattaagatt ggcaaaagtc ttttcttgat tacttttggt attttagttg
    17161 tctccttgct ttatttggat ctcacacatt ttctgtatac attacttagc tgttctattc
    17221 tatcttatac attgaataaa gtgaaatatc tggaaattgg atctgttttg ccccaattgg
    17281 aagcaaaaca gactacagaa acatttgaac cacttgaccc tcttgaacag ttagagcact
    17341 gattcttatt tttcactact ttatttacag aaatatcatt atgtaaacta aaatgatatt
    17401 attcagtaaa atcttcttta taaaaaaata aactattttt gcaaacgatc tgcgaaaata
    17461 gtttgttttt ttattttgcc attattttct tacttattgg gagaaaaaat tcgcttaagc
    17521 tcaaaaaaat ctgaggatac gatataaact tccggataga gtataaaata aggaaacgcc
    17581 gcagcgtttc ctttccaact gtagccgaat ataaatttgt atatcactta tttaaaatag
    17641 ctattttctc ccaaagagtt tccttgatca tcgatcaatc cttgtaatga gcgttctaaa
    17701 ataccatggc tttttttcga ttttttttct tctgactgct ttgtttcctc taacattttt
    17761 gttcgattga atgttcgtac agacggctca ccatttcttt tttcttgata cggcgtcggt
    17821 tcagtatcga acaacagata agagtcatcc gtttttttca tcgattcgat taaatgatcc
    17881 tcagaaattt tgctttctct agggtctggg ataatcgatg cgggtacata tttaggaaca
    17941 aaataagaac gctcccgcac cttcgtgtca acagatgcgt ttcgtgtagt atgcttggac
    18001 tctgtccttg tttcactttg tctgacagaa cgagaggaat caccaaaaag tttttttcgt
    18061 cctgtcgatg tgatttctga ttggtaatgg ccggtataat ccggtaattt tcctttatgc
    18121 ttttccaaat ttcccttacg cggagctgac ttcaatccat ttgttgcacg acgcttgcga
    18181 cggattttct cggtgttcgt gttcgtgaaa tgaaattctt tcatctgctc aaacggggac
    18241 tgattctgtt cagtcaaaag atcttcttgt ccgtcaaata atactcgctt cttgtcgttg
    18301 gttaatttta cgcctaactc atcatcgtac gcaggaaaac ggaaatgttt tcgtctgatt
    18361 tctttcattc aaaccatcct tctcaaaaat ggaacttttc tcaataatag cacagattca
    18421 ttgttttcag tagcaatgcg ctgattattt taagaaaata gcgatgaatt tcataaatat
    18481 atatatagta ataagactta attcgttgtc tctctgataa ctagttcagg aaaaaaacga
    18541 cgataacctt gactcgcccc tttttcttct atttttttta acaacatttc tccacatact
    18601 tcacccatac gtataatatc ttgcttgatc gttgtcaatt taggtgaact gatttggtct
    18661 aaaaataccc catcaaatcc aatcacacca aattcttcgg gcaagtgtcc tccagcattt
    18721 ataatccctc ttactgctcc tagtgctagc cgatctgaac tacatacaaa acaagtttta
    18781 tctgtaaaat ctgcccagtt ttctgtcata tatctttcta cttctgtcga atgatttgga
    18841 aaccgcaaga ttttactagg aagatcaact tccttcatca cagataaata accagtttcc
    18901 cttgaaattt caaaaggctc gtccacttcg ataccgatat aaataatcgt ttgataatct
    18961 ctttctaagg catattgcgt tgcttttgct gtaccatatt cattatcgct gtctacataa
    19021 tcatatcctt cagaattttc cccaaacaag acaactggtt tttccaaacg atcgatccaa
    19081 tcgaagtctt tttttctgac acctgtgatg atgtatccat cacaagaacc gacgtcgaag
    19141 gcatcatttg taactaattg gagagaataa tgcgctttac cgatccgttt agcgattccc
    19201 atcagcaaat tcatgtaata gggctcagtt gtgtcgattt cttccagtat aaataatttg
    19261 atgatctgcg accgattcgt gacaagtgct tttgcagcaa tatttggacg gtaatccagt
    19321 tcagccattg ctgagaaaac taactctttc aattcgtcag tcacctgttc cggatgattg
    19381 atgactcgag agaccgtcat ttttgaaaca ttggcacgtt ttgcaacatc tgctaaagtg
    19441 ggcatgctct cttcctttct aacatgttgt cattcttact atcaattata ccaaattttc
    19501 ctaacagagt ttattatagc ccaaaataaa aaacggaaaa tcctctatcg tcatgagtga
    19561 ttttccgttt caattattta tactttttta tcaaattttt tgctaaaaaa gtggaagctt
    19621 cttccattag tggtatttgt accatatgtc gctgtgtttt tgaggaacga aaaacaattt
    19681 cttttccgta agacttatgc cgattttttt ctacaaatcg ttccgtttgt atataaggga
    19741 ttttttcgtc agcttgtcca tgccaaaaga acagaggacg tccagctaac ttttccggct
    19801 gcaatgacaa atcatagctc ttaacccatg aaatcaaatc aaaatagtct tttggtacga
    19861 cataattata ttccgatccg cgccttacga tttcttttcc atattccaaa ggtgcagggg
    19921 aacccatcaa acacacgccc gctactatat gaggatgttt agccaacaag gcgcatgttg
    19981 tcattccccc catcgaaacc ccgccaactg caagctgatc atgtagaaga cctctttttt
    20041 ctaaatgctt gataagtgtg tcaaattcaa acagatttcc gtagatacta tcccaaaatg
    20101 tataggatgg aatagaagaa accggctgtt tgcgctcccc atgattcatc gcatctggca
    20161 ggatcacacg aatgccctgc tgcgcaattt ttcttccttg cgtcaaaact aactccttac
    20221 ttgtctgcca tccgtgataa tagatgacaa cgggaatacg ttcctctctt aattctttca
    20281 gaacaacttc taacactgga atatgatgga cagaacgttt caatataatt ggattcaatt
    20341 gttactcacc tattttcatt aaatttcctg atcgccatag caaccatgct ccaacagttg
    20401 tctggaacag gttcagtgta ccaaataata taaatgcagg actgaatggc tcgggaaata
    20461 agcacagaga acaaagtccc accactccta atgctagcga aaggagtgga taaatagaaa
    20521 aattcaaaaa actggcaacg ctaccgaaaa tattaccaat aaacagtatc aaaaagaaaa
    20581 aaacgcttaa aattaaacca tctgtcagcg acatctgaaa aacaatgttc tctacctcaa
    20641 ttggctgttg aatcgaatag acacctaagt atatactgag aaggagactt agcacgtggc
    20701 tggcacaaaa cacacgattg accgttttca ttttaatcac ctaacctatc tttataattc
    20761 tattataatc attttatcat tttttgtatg tataaagttt caatttttct tcacttacga
    20821 ttttttttga tattgttgtt atataaatga aaggagtttt acaaatgatt gatccaaaaa
    20881 tgttggggat gatcttcctc attaattttg cttatatcac tctgaacacg ttacgtttca
    20941 tgttgacaat gaaaggctat cgactgattg ctccacttgt cagtatggtc gagatcacga
    21001 tttatatcgt cggcttatcc cttgttttag atcgtttaga taatccactg aatttatttg
    21061 tctatgcgtt aggttacgca gtaggtatca gtgtcggaat tttgattgaa gacaaattgg
    21121 cattaggata catcatggtc acaacgattt tgccagcaaa tagcgcagaa gataaaagtt
    21181 tgccgggtat actgagagaa cacggttatg gtgtgacaca gacttctgca atggggctgg
    21241 aaggtgagcg gctagttctc gaaatacttt ctcctagaaa aagcgaacgt gaactgtatc
    21301 gcctgatcaa agaaatcgaa gagcgtgctt ttatcatttc ttatgagcca aaatatattt
    21361 caggtggttt ctggactaaa aaagtgagaa aacgacaagg aaaataactc acaaacttaa
    21421 aaactgtcta atatctaaat taaattttaa atgttagaca gtttttattt attattttga
    21481 ttaaaaaaca tcgacatata ctcatcaatt tgttattata ctttatatac ttatcaattt
    21541 aatttggaga tattatggaa attcaacgta gaaccactaa ttttttacat ttaggctctt
    21601 tttttgcaac tttgacgatc ttattttttc tatgttattc ataccttaag acctcacatg
    21661 cgccttctag tgcattaggc tggttgcttt tggatcattc tgatatcaca gaagccgaag
    21721 aaaatccgtt ttttttgatt ttgtcttctc tttgcggctt actgttttct gtttatttcg
    21781 gtgcctattt ttttcatcga catcctggta cgttaaacga agcttcaagc gtattgattg
    21841 catttaaaac gttttctttt ttagcaattc ttttttattc gtttaatcac aatacgcttt
    21901 tcttctttat catgaatggt ttagtcgtga ttttatccat ttttacttat tttatttttt
    21961 cactcatttt tagccaattg aaatgtccac tcttctttcg attagttcct gtcacctgtt
    22021 ttatttacag cttgttttcc ttttttgtcc ttgctttaat gccactgacc aacccttcga
    22081 cgatccaagt cgcaggaaat ctgttggata tgctcttcat cgtcagtcta ggtgtattta
    22141 tgtggcaaag aaaaaacaaa caaaataaaa agcattttga agcctgacta ttacgacttc
    22201 ataaatgctt ttttagtttt aaacacttca atctaaaaga ataacccaag attggataaa
    22261 ttattaatga ctcgccattc gtttcttagt gattctggat catcaaatgg acttcctaat
    22321 ctaagcagct agttcttccc ataaaatgct atacttgact gaatcataat attgattatt
    22381 taaaaatcta acttttctta tcactacttc ctttgtcatt ccacatttct caccattttt
    22441 ttgcattcct ttgtttccag accatgtagt gaatccaata ggtggtagat aggcaaaata
    22501 ctcaaataat tcttttaacc ataaaggaag agaaaggctc ctcctgcaag agtcagtata
    22561 atttttgctt actgctctct taggttttac tcactaaaac tgttctatat tctttgatat
    22621 aagaaaatgc atgcggtata aatttcttgc tcagctcaga aaagatttgt cgtttaagaa
    22681 aggccgtttc ctccattgtc aatgaaggat ccaatgttgg taattcaatc tcaaaattgt
    22741 ttttttcgac aataggtaat tctaatgtga atgattcttc ttcctttata gtattcgtca
    22801 caagtagaga ctgatggaaa atactaggcc ggcgattttt atatttattc ttacgtatcc
    22861 tgtcaacgat aacttctatt tgatcaaaaa agtacgcttc atttacgtct ccaataagtt
    22921 cggctaattc tttgaatgcc ttcgttacag gaagctgatt cttctgtaca aaaaagtaat
    22981 tagccaaagt aagcgggaag tgttctatag aggaaagtgt gataaaacgg tacttctcat
    23041 ttcctgcagt tgccctcagc aattctgtct ctcggctgtt tcttactcca taaaaatacg
    23101 cttctttccg ttcatcttcg aaacaatacg cccaaataac ttctcccatc gctaattttt
    23161 gttcatcaac agagagtctc ttcaattgtt cagctatggt ttcagcagcc gaagtggctt
    23221 gttgcaagta atctttagga tcaaatattg gaaagttcaa atgatatctt cgttcttccc
    23281 tcttgattaa tcctgcatcg atcaatagat caagaaaatg ggaaaattta ttttgcgaaa
    23341 attctttttt caattctctt agaatcgttt cttgttctcg atgttcatat agataatcgg
    23401 tcaatgaaga aaaaagcgga tcatcggtca gtttttgata aaagttttcc ttattttttg
    23461 aataataata gttcatatat gttctctttt ctatccgttt tattttactt aaaaggcttt
    23521 tacgtaaaaa ggaggaagaa caagagtcat aattgactgt tattctcctc catttcttcg
    23581 gcctttagta tgttctatgt ttctttttat atcaatcgct tatccattca ttttgaatgc
    23641 ttcatactac cctttgatta gctaaataca gccgtcaatt gaggtacgac ttgtttttta
    23701 cgtgaaacga cacctttaag caaagcacgg ttgttggtca aagttgtttg gaaagcttct
    23761 tctacttttt cttttccttt accagcaaca agtaattctg aatcactgtc taagatgttt
    23821 gtgacaacta atacgaacag atcgtagcca tttgctttca tttcatcttc cattgctgct
    23881 tctagctctg cttgtcgatc catcacttca ttaagatcca ctgtattgac ttgagcgata
    23941 cgaacgttgg aactgcccat tgggaaactt tttgcatcca aatcaagaag aaccgcagct
    24001 gatttatcac ttagatttgt tcctgctttc aacatttcaa gtccataagt gtttagatcg
    24061 acttcagcga ttgctgcaag ttcttttgca gctgcttcat cttcaggcgt acatgttggt
    24121 gatttgaaca acaatgtatc tgaaatgata gctgagagca tgattcctgc gatttcttta
    24181 ggaattgtta cttggttttc tttatatagt tttaaaataa tcgtacttgt acatccaact
    24241 ggttctgcac gatagtacaa tggattagct gtttcaaagt ttgcaatacg atggtggtct
    24301 actacagcta aaatatttac ttcgctgata tctgaaatac tttgttggaa ttcattatga
    24361 tccacaagca tgacatctgc attttctgct ttagctgact ctactactcg tggtgcagat
    24421 agctgaaagt ggtctaatgc gtattgtgtt tcttcattag gtgtacctag agcaactgct
    24481 tctgtttctt tacctaattc attttgcaag tgtgaaaacg caatggctgc cccgattgca
    24541 tctgtatctg gattttggtg accaaaaact aaaatttttg acatgtcatt cgctcctttg
    24601 tgatttctcc tatttaataa tagcaaaaaa acggaaagaa gcaatactta tcttctttcc
    24661 gatgcgacct atcgcgttaa atattttgta tactcttctg tatgaagcaa tcgtttagca
    24721 ttttcgacac gttcttttgt aggtggttcg atcccttcta atggatattt caaaccaagt
    24781 gtttcccact tgtattttcc catcgtatga taaggaagaa tctctactct gtctacattt
    24841 gacaaggttt gaataaagtt gtctagtcgg atcaaatatt catcataatc acttcgctca
    24901 ggaactagta catggcgaat ccaaaccggt ttgttgattt ttgacaaata ttgagccatt
    24961 tctaaaatat tttcattgtc ccaatgcgtt agttttttat gctcttcatt atcgatgtgt
    25021 ttgatgtcaa ataacagtaa atctgtatac ttcatcaatt cttgaaaacg tgaaaagaaa
    25081 ggttcttcat acgtaaaagg ttttccgcat gtatccaatg tagtatgcat cttccgctct
    25141 tttgcttttt taaatagttc gatcaaaaaa tcgatctgca atagaggttc tccaccacta
    25201 acagtaatac cacctttatt tccccagtaa ggtctgaagc gttctgcttt atctaaaagt
    25261 tcatctgctg tgtattcttt ccctccgcca atattccaag tatctggatt gtgacaaaat
    25321 tggcaacgca tgcggcatcc ttgcataaac acgacaaagc gcagtccagg tccgtctact
    25381 gaaccgaaag tttcgataga atgaacatag ccgattgttt tttcttccat ttaagttcac
    25441 atcttttctt tgatttcatt ttaagtacaa gttagctgtc gaagcgaagc tttctgaaca
    25501 aaatttttcg caattgccgc ttcgttatgt gtaaaattta cagggacgga acatacaagt
    25561 cctgcccctg taaatcgttt ctttcaaata agcatactga ttattcgatt ttgatgcgat
    25621 ggctattcaa cgtcctttcg acgctaagtc gaaaaacttt tttcacgaac tttttacatt
    25681 ctgtcgtgtg aagttctcat caagacatct aattgttgtt ctcttgtcaa gtcacggaat
    25741 ttaactgcat aaccagatac ccggatcgtc aagttcggat atttcattgg attttccatt
    25801 gcatcacgca ataaatcatt actgaataca ttgacattca aatgataagc tccttttgag
    25861 aagtatccat ctaagacatt acgcaagttt tcgattcttg tatcttgttc ttttccaaga
    25921 cctgaaggat tgattgtttg ggtatttgaa attccatcca atgcacagcc gtaattcatt
    25981 ttagctgttg agttcaggct agctaataac ccactttgtt ccgcattgta acttggattt
    26041 gctcctggcg caagtggttt tccagcttca cggccatcag gagtatttcc tgtattttta
    26101 ccgtaaacaa catttgaagt aatcgtcaat aatgaagttg ttggttttga gttgcggtaa
    26161 gttttatgac gtttgatttg tcccatgaag tattccaaga tccatgaaac taattcatct
    26221 gcacggtcat catcatttcc gtatttaggg aagtcgccat ccacttcaaa atcaactgct
    26281 attccttttt cattacggat tgcttttact tttgcatatt tgatcgctga caagctgtct
    26341 gccgcatgag aaatcccagc aatacctgta gcaaatgtgc gttgcaagtc agaatccatc
    26401 aaagccagct gagctgcttc ataagaatat ttatcatgca tataatgaat gatgttcaac
    26461 gtattgacat atagttctgc taaccaatcc atcatattca tgaagttatg tttcacttct
    26521 tcaaagtcta gtatttctga tgtgattgga cgatattctg gtccaacttg ggcgccagtc
    26581 acttcatcga ctccgccatt gatggcatat aatagtgttt tagccaagtt agcacgagca
    26641 ccaaagaatt gcatgtcttt tccgacaact gttcctgata cacagcaagc aatcgcacaa
    26701 tcatcagaac cccattgttc acgaagctga ttatcatttt cgaattgaat cgaagaactt
    26761 tcgatagcga ttctgctagc atatgttctg aatccttctg gaaggtgttc agaatacaaa
    26821 acagtcaagt ttggttctgg tgaaggtccc atatttgtta atgtatgaag cagacggaaa
    26881 tcattctttg taactaatga acgaccatct aatcccatac ctgcaatgga taaagtagcc
    26941 cagataggga atcctgagaa taattggtta tattcaggtg tacgcgcgaa tttgaccata
    27001 cgtaatttca ttactaagtg gtcgatcaat tcttgtgctt ctttttctgt gattactcca
    27061 ttatccaaat cacgttggat atagatatca aggaatgctg agatacgtcc gattgacatc
    27121 gcagcaccat tttgtgattt gattgctgct aaatatccga agtatagcca ttggacagct
    27181 tcttttgcat ttgcagctgg tttagaaata tcatagccat atttcgcagc catttctttc
    27241 atttgcgcta atgcacgata ttgttcagtg atttcttcac gtaaacgaat cacttcttca
    27301 ctcattgtat gataaccagt catatcatga tcttttttct tttgttccat caaatagtcg
    27361 attccataca atgccacacg acgatagtca ccgatgatac gtccgcgacc gtaagcgtct
    27421 ggaagccctg taatgatttt gtttttacga gcagcacgca tttcagcagt ataagcgtca
    27481 aatacacctt gattatgtgt tttgcgccag tcagtgaaaa tatgtgtcaa ttcatcgttt
    27541 ggtgtatagc cattactttt tagcgcattg ttagccatat tgattccgcc gaacggcatg
    27601 aatgcttgtt tcaaaggttt gtctgtctgt agaccgacga ttttttccaa atctttatcc
    27661 aaatagcctg catcgtgtga agtaatagtt gatacgattt ctgtgtccat atcatagaca
    27721 ccgttacgct cgaattggat atcatttaac ttttgcaatt catcccataa tttttctgtt
    27781 gcttctgttg ggccttccaa aaagctgtca tcaccgcgat attcagtgta gttattttga
    27841 ataaagtctc tagtgtctac gccttctttc catttggtac ctttaaatcc attccattgc
    27901 tccattgtat ggacctccta aatttctgtt ttatgtaaca gtttttacgt gattagtata
    27961 acacaggacc ctatctttgc aagggttttc ttgtttttta tttaacaatt tttatgtttt
    28021 atttacatat atttaaatca acgttgacat accaacattt aagcattgtg aacactttca
    28081 tctttttttg caaacgtata aggatttatt aaaaatgaat gaaaaagaga cgccgcctgt
    28141 at
//
LOCUS       DAPBCF010000033        28033 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.033, whole genome shotgun sequence.
ACCESSION   DAPBCF010000033 DAPBCF010000000
VERSION     DAPBCF010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28033
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.033"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            185..1183
                     /locus_tag="RD508_001791"
     CDS             185..1183
                     /locus_tag="RD508_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7736351.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="RD508_001792"
     CDS             1295..1804
                     /locus_tag="RD508_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HDT7736352.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1834..2493)
                     /locus_tag="RD508_001793"
     CDS             complement(1834..2493)
                     /locus_tag="RD508_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HDT7736353.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2495..3259)
                     /locus_tag="RD508_001794"
     CDS             complement(2495..3259)
                     /locus_tag="RD508_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HDT7736354.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3267..3944)
                     /locus_tag="RD508_001795"
     CDS             complement(3267..3944)
                     /locus_tag="RD508_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HDT7736355.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3981..5366)
                     /locus_tag="RD508_001796"
     CDS             complement(3981..5366)
                     /locus_tag="RD508_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDT7736356.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5576..5660)
                     /gene="ffs"
                     /locus_tag="RD508_001797"
     ncRNA           complement(5576..5660)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="RD508_001797"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="RD508_001798"
     CDS             complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="RD508_001798"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HDT7736357.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6305..7162
                     /locus_tag="RD508_001799"
     CDS             6305..7162
                     /locus_tag="RD508_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7736358.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7243..7578)
                     /locus_tag="RD508_001800"
     CDS             complement(7243..7578)
                     /locus_tag="RD508_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736359.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7645..9015)
                     /locus_tag="RD508_001801"
     CDS             complement(7645..9015)
                     /locus_tag="RD508_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HDT7736360.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9093..9629)
                     /locus_tag="RD508_001802"
     CDS             complement(9093..9629)
                     /locus_tag="RD508_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7736361.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9938..11419
                     /locus_tag="RD508_001803"
     CDS             9938..11419
                     /locus_tag="RD508_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7736362.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(11522..12229)
                     /locus_tag="RD508_001804"
     CDS             complement(11522..12229)
                     /locus_tag="RD508_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HDT7736363.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(12308..12646)
                     /locus_tag="RD508_001805"
     CDS             complement(12308..12646)
                     /locus_tag="RD508_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HDT7736364.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(12757..13719)
                     /locus_tag="RD508_001806"
     CDS             complement(12757..13719)
                     /locus_tag="RD508_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HDT7736365.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(13734..15065)
                     /locus_tag="RD508_001807"
     CDS             complement(13734..15065)
                     /locus_tag="RD508_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7736366.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(15073..15753)
                     /locus_tag="RD508_001808"
     CDS             complement(15073..15753)
                     /locus_tag="RD508_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDT7736367.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(15972..16451)
                     /locus_tag="RD508_001809"
     CDS             complement(15972..16451)
                     /locus_tag="RD508_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HDT7736368.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(16578..18257)
                     /locus_tag="RD508_001810"
     CDS             complement(16578..18257)
                     /locus_tag="RD508_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDT7736369.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            18805..20307
                     /locus_tag="RD508_001811"
     CDS             18805..20307
                     /locus_tag="RD508_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7736370.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            20320..20982
                     /locus_tag="RD508_001812"
     CDS             20320..20982
                     /locus_tag="RD508_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7736371.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(21083..21286)
                     /locus_tag="RD508_001813"
     CDS             complement(21083..21286)
                     /locus_tag="RD508_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDT7736372.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(21397..22581)
                     /gene="iadA"
                     /locus_tag="RD508_001814"
     CDS             complement(21397..22581)
                     /gene="iadA"
                     /locus_tag="RD508_001814"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HDT7736373.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(22738..24477)
                     /gene="yfcC"
                     /locus_tag="RD508_001815"
     CDS             complement(22738..24477)
                     /gene="yfcC"
                     /locus_tag="RD508_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDT7736374.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(25250..25864)
                     /locus_tag="RD508_001816"
     CDS             complement(25250..25864)
                     /locus_tag="RD508_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7736375.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(26470..26847)
                     /locus_tag="RD508_001817"
     CDS             complement(26470..26847)
                     /locus_tag="RD508_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736376.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(27147..28028)
                     /gene="galU"
                     /locus_tag="RD508_001818"
     CDS             complement(27147..28028)
                     /gene="galU"
                     /locus_tag="RD508_001818"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDT7736377.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         8326 a         5875 c         4686 g         9146 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct tttttgtttg
     1861 tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta ataatacaaa
     1921 aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga ttggatcagt
     1981 aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa ggataaaaaa
     2041 gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca tgccgatttg
     2101 aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga taaacaaaat
     2161 actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa ttttcacttc
     2221 ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga ggatggtttt
     2281 gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg tctcttgatc
     2341 taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata gtggtcgaaa
     2401 gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga acaatccagc
     2461 atattccatc cactgccatc tcgaattttt catattagaa gctccattca tccagtgatt
     2521 gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt gtaaaacctg
     2581 ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct gtttcatagt
     2641 tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg gctttatcca
     2701 taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct gtctctacaa
     2761 aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata ttcttatctg
     2821 ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta actacttttt
     2881 cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct tcttcccatg
     2941 taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca tagacttttt
     3001 tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg tagactgtct
     3061 ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt tctggtgact
     3121 tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat tcttccacaa
     3181 atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct aaatcaatta
     3241 aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt aaatgctgtt
     3301 tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga ggtttttgct
     3361 gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac tggtcctttt
     3421 ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg agttgtcttt
     3481 tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt gcaatattcg
     3541 taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg attatccgct
     3601 tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat ataatcatat
     3661 cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc ttcacgataa
     3721 tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc taacagtgtc
     3781 actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc caaagcagct
     3841 gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt agcaatttct
     3901 gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc accacctatc
     3961 ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta atctcctacc
     4021 acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc aatcgttgga
     4081 aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt attcagatcg
     4141 attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat tccattatag
     4201 accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata gttacgtaaa
     4261 aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc acccaatgtg
     4321 acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg attgacccgc
     4381 ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc cgtctttcct
     4441 cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa gatatctaga
     4501 ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg cccacgttct
     4561 agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc ggtagggatg
     4621 gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg gacttcaccg
     4681 acatactgcc cgtactttcc agcggctgct atttggacat cattgattac gtgaccttct
     4741 ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat ttcttttgca
     4801 atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc cacttgtgaa
     4861 cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc ccagccattc
     4921 ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt cgtctggtgt
     4981 ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt atttttatcg
     5041 aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt caactcttct
     5101 ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc aacttcattc
     5161 atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca acgatccaca
     5221 aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt ttctcgttta
     5281 cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg cagatcattc
     5341 gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct ttatcatacc
     5401 ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc tgccttgaag
     5461 caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag gaacattcat
     5521 ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg tttcattata
     5581 atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac acgcttcaca
     5641 agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt cattcgttga
     5701 ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt cagtcaaaat
     5761 catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt taaaccgctc
     5821 gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat acgcgccgaa
     5881 ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac aaggctctaa
     5941 ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac aggcttcctt
     6001 gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa ggttatatcc
     6061 tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt catgaagcat
     6121 ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt ctactgcatc
     6181 aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt tactttagca
     6241 tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac aagaggtgaa
     6301 caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc
     6361 agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca
     6421 agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga
     6481 tcaaaaaaaa cacccatggt atcactatct ttttaaagat gcttcttgtg ttcaagaaaa
     6541 aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa aaaaagaatg
     6601 gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt atacagacac
     6661 agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatgctactg aaatcaacgg
     6721 tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg ttggttcttt
     6781 ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa tttttttaac
     6841 agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg tggctttaca
     6901 ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca tagaactgat
     6961 caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag gcaatgtcag
     7021 ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa tcgaaaaatt
     7081 tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt gctatctttt
     7141 attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa ttttgtcaca
     7201 accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca ttttttcaac
     7261 aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat caccataaac
     7321 agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag aatccaagtc
     7381 actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa atttgtcata
     7441 gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca ttacttttcc
     7501 cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc cgattgttac
     7561 ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca tagcatagac
     7621 aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga aaaagttctt
     7681 tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata ctagcaaaac
     7741 ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt gccattcctt
     7801 ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg ctaatgcata
     7861 gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac gtacgacttt
     7921 taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt tgaacactaa
     7981 aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga gtttttcctg
     8041 ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat gcatctgatt
     8101 ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt tatgaggcca
     8161 tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc ctgaactaac
     8221 ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa gccagctaat
     8281 gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt gtcctttatt
     8341 ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac agtatagcgg
     8401 agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc cttctcctga
     8461 acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga caagttctgc
     8521 gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat tttctgataa
     8581 aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc ccttcatttg
     8641 agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa ctttttcacc
     8701 gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc tatattcata
     8761 cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct cattgctgta
     8821 gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc ctgccggttt
     8881 tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag aaaaaaaatc
     8941 ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg gtaacgttgt
     9001 cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt acgaaaaata
     9061 aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt taagatattt
     9121 tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat ttcaagaaaa
     9181 tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac caattcaagc
     9241 gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg ccgcttaaat
     9301 agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc atggatagaa
     9361 aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca ttcagctaag
     9421 tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc gctgattgat
     9481 ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa ctctcttgca
     9541 gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag caaatattct
     9601 ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca tctacccata
     9661 aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca tatttagtta
     9721 tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca aaatacccta
     9781 ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta tataaaaaag
     9841 aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac agtttttgtc
     9901 taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag caagaaaaaa
     9961 agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac aagaattatc
    10021 caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa taaatgtatc
    10081 actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag gagagatcca
    10141 aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa aattatgcta
    10201 cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc cacaaactgc
    10261 tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc tcgaaaaact
    10321 gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat ctgtaaaaaa
    10381 ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact tttttctttc
    10441 agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg cactaaaaat
    10501 gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata tctacttgct
    10561 gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa cttcttctga
    10621 aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat actttacttc
    10681 tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact ttaattattt
    10741 tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga ttggtttttt
    10801 attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga cttacttaac
    10861 tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt attttcttgt
    10921 gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt ctacactttg
    10981 ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga aattaagaga
    11041 aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc aataccttag
    11101 tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca tccatttgca
    11161 gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc agttatttcg
    11221 caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca ttacagatca
    11281 gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc acaatacagt
    11341 gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag gttatgagaa
    11401 caaaacaaag aggatgtgac aaaattcttg tcacatcctc ttattccaaa taaatggtat
    11461 tcaatcagct aactctcggt attagctcag atcaaagcgc tgatttcaca acttctttat
    11521 tttaatctct tcggttgccg ccgaacaata agatcaagcg caacagctgc aggaatgtcg
    11581 aaagcgctgc tgcaacataa gtcagtgctg ctgcaaataa tacgtgtctt gccatcggta
    11641 cttcttcttc cgtcagtagt ccgccttcac tcaaaatttg gattgctcgc cgagacgcgt
    11701 taaattcgac tggtaatgtc accaattgga aaagtaatgc taaagaaaaa gcgaaaatcc
    11761 cgatattgat taacgtagag ttccagctaa gcaatacacc taccataatc aaggggaacg
    11821 aaatcatcga accaaagtta gctgctggaa caagtgctgc acgaatcttc aatgggacat
    11881 aacccgaagc atcttgtacc gcatgtccgc attcatgagc tgctacacct atcgcagcaa
    11941 ctgaagtaga ctgtgcagtt gcttgagaca aactcaacat cttattacct gaattgtagt
    12001 tatctgtgag atctccggca atttgttgaa caccgacatt atttatctgt tgactttgta
    12061 atatatattg tgctgcttgt gtaccagtca cattgttttt gcttctcact tgatcgtatt
    12121 ttcggaaagt actattgacg tacgctgacg caattccgga aataactaat ccaagaatga
    12181 ccaaaagaaa tgtcggatct aaaaaaccat acattccata accatacatt ttcgtttcac
    12241 tccttttcgt ttactttatt ttatcattag tagtaggaaa agaatgtgaa aagaccttga
    12301 atattcttta attctttttc acaaattccg atttcagttt catcggtcca aatccttcta
    12361 ccttgcaatc gatattatga tcgccttcta ctaaacggat gttcttgact tttgttcctt
    12421 gtttaatggc acctgacgca ccttttactt tcaagtcttt aatcactgtc acgctatcgc
    12481 cctctaacag acggtttcca tttgcatcta ataccactaa tccgtcttct atgacagttt
    12541 cttgttcttc tttgttccat tcgttcccgc attctgggca aatcaacaag cctcgatctt
    12601 catatgtgta ctctgagcca cattctgggc aatttggtaa tgtcatcttc tttctccttt
    12661 aaaatcttta gtgagcacta ttgtaacgga aaaagaagat cttgaaaaga tacatttgtg
    12721 atttttacta caaaaggcac gttttcgaac gaagtatcat tctgtttttc tgctcttata
    12781 cgattggcat atatcttgga tctctttata gatttcctct acttctgcta aatcttttgc
    12841 attcgcacca cttgctaatg gatggcctcc tccatgatgg cgtttagcca attcattgat
    12901 gatcggcccc ttagaacgta aacgtacgcg gtaataccct gaaggctgct gaacaaaaat
    12961 cccccaagcc agcacttcgt caatcactcc aggaagtgaa acgatcgaag ctgtctctga
    13021 atcatcgatt ccatatttat caagaatttc ttgcggaagg attattcttc ctgcaccatt
    13081 ttcatccacc tggatatttt gataaagata accggaaagt ttagcgactt tcatcggcat
    13141 ttgttcaatc tctctgttca aagcacttgc atcaaatgga taatttctca atatcgaagc
    13201 aatctctaat gtacgggacg tcgtggaggg atacaaaaag cgccctgtat ctccgacgat
    13261 tcctgcataa agtaaccgtg cagccttaac gttcatcttt aaagattcag gaaacatcaa
    13321 agcaaattct gcaatcatct cactacagct acttgctttt gtatttaccc acacaagatc
    13381 tccataaggg tcatcattgg gatgatggtc gattttgatc agtttttctg ccaactgata
    13441 tctttgatca ctgattctgg gtgaattagc tgtatcagtc acgatgacta gcgctccttg
    13501 gtagaagaca tcttcaactt cttgcatttc tgctaaaaag cgaagccctt caatcgtttc
    13561 acctacttga cgtatttctt tttctgggaa actttcccgt aatagttcgg ctaatcctac
    13621 ttgtgatcct aatgcatcag gatcagggcg caaatgcctg tggataatga ttttatcgta
    13681 tttttttatt gtatctacta tttcttgctg tactgtcatt tcactcctgc tttctaagaa
    13741 cgttccatta cttgacaaac aacgattgct ttggaaacga tggtgttttc aataaacact
    13801 tcgatatcca gtttagcgga acgtctgccg atttccaata cacgtggacg aatgtctaat
    13861 tcgctttcca attggatcag ccgcaaataa tgtaggttca cttgttcaat caagatattt
    13921 cgtttttggt tcatcaccat tgttttttgt gcgacatcag aaatgatttc gctaagtacg
    13981 ccaaaagaaa tggttccaac gccattgacc atttgtggtg ctactacgaa tttgaactta
    14041 gggttttcca aacgatttcc ttcacggtca gtatcaatcg tatggatatt tccagatatc
    14101 tgatccgaaa tcgtatctgc aatctgcggt tgtcgctgga caagctgcat cgctttcatt
    14161 acatcttgcc gggtaatcaa gccttccaat gtcaagtcat cggaaacgac cggcatgact
    14221 tctagcccat cccagatcat ttgatggcta acagaggcaa tactcattgt tttctttaca
    14281 ctgattggtt ctttcgtcat cacccgatcg atgatctggt ttggcgattt ccctaaaaca
    14341 tcttttgccg taacaatccc catcaaacga tgatggcggt tgacgactgg aaaacgcgaa
    14401 tgctgcgttt cttctgacaa acgctgataa tcagaaatcg tatctgtctg ctgcaaataa
    14461 tgagtctttt cagctggcat atagatatca ctgacaagca tgatatcttt tttgatcaat
    14521 tggtcgctta acgctcggtt gatcatggtt gcgactgtaa atgtatcata agaggtgcgt
    14581 aagatcggca tttcaagatc atcagctagc tttgcaatct cagcagtcgt attgaatcct
    14641 cctgtgatca atactgcggc gccatcttcc aatgctaatt tttggacttc cgcccggttg
    14701 ccgacgatca ttagtgatcc tggcgtaata tagcgttcca tggcatgttt agtcatcgcg
    14761 ccgatgacga atttattcaa gaccttgtct aatcctgccg ccccgcctaa aacgtcccct
    14821 tcaatgatcc tgacgacctc gccaaatgtc aaacgttcaa tatgtttttt taatttgcgt
    14881 tcgatacgga tggtccctac tcgttgaatt gttgaaacta gtccgacatt ttctgcatct
    14941 ttgattgcac ggtacgctgt tccttcactg acattcaatt cttttgcgat gcttcttaca
    15001 gaaattcgat tgccaacagg taaactttca atatattcta aaatcaaatc atgttttgtc
    15061 gccattttct gcctacactt ccagcgtttc cgagacgctc attatttttc cttcactatc
    15121 ttccagtaac tctacaaaag attcgggatc ttgttcaatg acagggaaag tattgtaatg
    15181 gattggaact actttcttgg cacgaattgt ttgcgcagcc tttgctgcat cttctggccc
    15241 catcgtatag ttatcgccaa tcggcaagaa agcgacatca atatcgaatt cttctgcaag
    15301 caatcctaga tcactgaaat aagcagtatc ccctgcatga taaatcgttt ttccttctgc
    15361 ttgaataata attccgctag gctcgcccat atactgaacg ataccgtcta cttcatagct
    15421 tgaactatgc tgtgcatgta cgaattttac cacgccgaat ggaaacgcat gttttccacc
    15481 gatattcata ccgaatgaat ctactcctct gctgttcgca taatcagcaa tctcaacaat
    15541 actgataatt gtggcttgat tttcttttgc aataggaatc atatctccta tgtggtcact
    15601 atgaccatga gtaatcagca accaatctgt ctttacttct tctgcagtta agtctgtcaa
    15661 tggatttcct gtaataaacg ggtcaatcat cacgcgttgg ccattttcca tttcaattgt
    15721 taaacaggaa tgtccatgat acgtaatttt catattttac acctcgcgtt ttctctgtat
    15781 cttttttatt aaaaacgatt tcatcacttg cacatcaatg aaaaaatata gctgctaaat
    15841 atattttcat tggattgata gtacagtatg tacaaagcaa ttgtaacaga taatacagga
    15901 tgcaccaagt accaagcaga tataatctca agtttgaggt ctctgctctg cttagcttct
    15961 cttctcgtcc cttaactaat taaatcagcg taaataggat ggacgatctt ttctaaatcg
    16021 gctactttta tccgaaggct tctcccgatt tcaccgcttg acacaattac ttcttctttt
    16081 tcttttaaag aactgtctgc taaaaaacaa taatcaggat gtgcgagttt tattccaata
    16141 ggggtgtttg ctccgtgggg atatcctgta tgcattaata caaaatccat tccaggaaaa
    16201 ccaactttac gatctttcgt cacttgtctc gtttttttgt aatctaagtg atcgttcaaa
    16261 ggaatcaatg cgatgatcac cccagttttg tttcctttca ctacgagagt tttacatatc
    16321 aaagctggat caatccctct tttttgtagt tcttctgtga aagattcttc taccacatga
    16381 ctaaaatcaa gtggttgata gctgatcttt tgttcttcta aataacgttc gacttttgtt
    16441 tgactcatca ttgattcact ccctttattc tatcgtttat tataaagcga gggatgctgt
    16501 attcaaaaat tatttgtttt tcgcaaaaaa agagcaagac gagcactcta tagagaggtt
    16561 catcttactc tttttgttta ttttttattt cgacgttgag tagcttccat aatgactggc
    16621 aagatcactg ggcggcgttt tgtttgttca aataagtaac ggcctaattg atctcggatg
    16681 tcttgcttta atttgctcca ctcaaaatca ttgctttcta aatgtttctc aacgattgtt
    16741 tcaatcatat tgctgctttc tttcatcaga tcacggctag cttttacgta aacgaatccc
    16801 cgtgaagtaa tttgaggttt tgaaatgatt ttcttttctc gccgactgat agtgacaacc
    16861 gctacgaaaa tcccgtcttc tgacaagatt tttcgatcac gtaaaacaat gtttccgata
    16921 tcacctatgc ctaatccatc aatcattaca ttttctgcac ttgtagttcc tgcaacactc
    16981 atacgcttgt tcttatattc cagcacgtct ccgcgtccag taatatagat atttttgtat
    17041 ggcatcccta ctgcatgagc caaatctgca tgagcagcta attcacgata ctctccttga
    17101 actggcacaa aatatgttgg tttcatcaaa ttgatcatta attgcaagtc attaggattg
    17161 gcatggccag aaacgcgcat attctcagag atcaacttca ctgttccacc agctcgataa
    17221 atgatatctt ccgttttcgc cacgatggtt tccatcgcga tgcttggcgt agtagtgata
    17281 taaaccaaat ctccttcttc aatcttgaca ttacggtgtg taccgtttgc cattttttgc
    17341 agagacttga tgggttcacc cattcggcca gtttctaaaa tgatcagttc ttctggatca
    17401 tagtttttca tgtctttcaa cgtaacaagc agatcttcac ttggtaattg aagtttttct
    17461 aaacgcatcg ctgtgcgaat aattcgttcg aaatcttgac cagtcaagac aacttttcgt
    17521 tgtgcttttt ctgctgcatc caatacttgt tgcactcgtt gcaaattact tgctacacaa
    17581 gcgacgatga tacgcccttc ccaatatttg atcgtatcaa atacttcatc tgctatttgg
    17641 gcttcagaag ctacaggctg aggattttct gcatttgccg attcacttag taaggctaag
    17701 actccttctt tgccgatttc cgccaatcgt gcataatctg tttgatacat tgggatagcc
    17761 gtttggtcaa atttaaaatc tcccgtataa acgatactac cttcttttgt tttcagattg
    17821 atccccactg aatctggtat cgtatgagtg gtacggaaaa agctcactac tgtttcacca
    17881 aagtctattt ctgtatgctc atctaccaca tggaaatcct taaatccttt ggctgcttca
    17941 ttacgactga cattcaattt tgctaactcg atcgtcaact ctgtcccgaa tactggtaca
    18001 gaaatttttg acaacaagta aggaagtgcc ccgatcgcat ctgcatgtcc atgtgttaaa
    18061 aagacaccag ctacacgatc aatgttttct tctaaatacg taaaatcagg gattacgacg
    18121 tcgatcccca acaactcatt ttcaggatat tttagcccac aatctaaaat aaaaatatcc
    18181 tcgcccactt ctgcgacata catgtttttt ccattttcac gaacgccgcc taatgggata
    18241 attttaatgg tactcacaaa cttcacctct tcttatgaca tccaagttta aagatgtcga
    18301 ttttcttctt tatctaaata tatgagccat tccaatgaag catatgcaaa atcactattt
    18361 ctcaacttat ggagaatcag caggaaaatt accagcacat ccgcgttctg acagttggat
    18421 gggcatttta ttttggatat acttcattaa caaaatggat cttttgcgaa acgctatagc
    18481 cagaatactt atataagtat tcagctgttc cccattatta tacaacaaat aaactaaatc
    18541 gctagtatca gcaattgtta gaacaactat gcacgtaaaa atccctctgt agcatctagg
    18601 atttcttttg ctattcctct ttcatttctt cttcgtcggt ttgaaacata cttttttcat
    18661 tttaccacat tttttgcaat aactatagtg actttttata tatacagaac ctcatgttga
    18721 tggtgtgcaa acagcataag atttaagcta gctttaagat aggttgtcta ttatcaaatg
    18781 catctactag gagggatgca aaatatgaat tttatgaaac gtgcatggaa aagtacaaaa
    18841 gtaaaatggg gacgttcatt gttattgttt gccgtgttca cagccattct tatttttgtg
    18901 ctagctggcc tcacgattcg aagcgctgca gaagaagcag cgaatcaagc acaaaaagaa
    18961 gttggagcaa cagtgacttt aagtgccaat cgagaagctt catttaaaaa acaggaacaa
    19021 acttcttcaa gcggttctac cactgaagaa cgtccagatc caggcagttt ttctcttaca
    19081 ccagtttcct taacggacgc ggaaaaaata gctgaattag ataatgtaaa gagttattcc
    19141 tttgaaagtt ccgcctcagc tatggcaaaa gatggaataa ctgccatcac tagttctgat
    19201 tcaagtgaag acagttcaga aactactgat gcaggcggtg aacctgctgg aggaatgggc
    19261 gggaatccgc aaatgactca agcagacttt caaatcagtg gtgtgtcagc aactgcacaa
    19321 aatagtaatt tttctgatgg aacagcaaaa atcacggatg gtgaaggaat agatgacagc
    19381 gacaaaggca caaacaatgt agtcattgat tctactctag cagaaacaaa tgacctggca
    19441 gtcggagata ctttcacaat cacgagtact gaagatgaag ataccactta tgaaatgacg
    19501 atcaaaggaa tttatgaatc cagcgaaaca agcggcagta tgggtatgaa attcaacttc
    19561 atgaatccgt cgaatacact ttacacttct tacacttttg caaatgaact aaatgggaca
    19621 tctgacgata acacgataga ttctgctatt tacactctat ctgatccaga taaaatggat
    19681 gagtttctca aagaagctga gaagctgatc gacacagata catttagctt acaatcaaat
    19741 gattccatgt atcagtcaat gttggaacct ttaaacaacg tggcaagttt ttctaaaaat
    19801 gttgttttac tagtggctgt agccggtatt atcatactta ctctgatcat tatgattacc
    19861 attcgggagc gtcggcatga gttaggcgtc ttgctatctt taggagaatc cagaagtaaa
    19921 atcattctcc aattgtttac cgaagtggct atttgtatga ttcttgcatt aggagttgct
    19981 tcgcttagcg gaaacgtcgt cgcgaatgcc gtgggacagc agctacttga ccaacagaca
    20041 gaaaccacga cacaaaacca gcaagctcct ggcggtggac aaatgccagg taacagacaa
    20101 gaacaaggcg gtcaacgcga tggtcaacaa ggaaccacga ataatccatt tgctgtttct
    20161 gatcaagtca gcgaattgga aatcaatgtc aaacctgcac aattgggact attagccgga
    20221 gtagcatttg gaatcagtct gttttctgtc tttttagctt ctatagggat attaagatta
    20281 aacccaagaa aaatcctatt aaactaaagg aggaatttga tgttacggac agaacaattg
    20341 ggattttggt atcaagatcc gcaagatgcg ctttataaag atgtagaact gaatttcgaa
    20401 gctggaaaaa tgtacgctat tttaggagca agtggttctg gaaaaacgac ttttctttcg
    20461 cttatttctg gactagatgc accaaaagaa ggaaaggtat actatcaaga tcgttcactg
    20521 aacaaaatcg ggttaagaag ttatcgtaaa aatgatgtct cgattatttt ccaagcttac
    20581 aacttgcttc cttatttatc ggctctagac aacgtcatag cagcaatgga aatcactaag
    20641 accaagcaag agaattatcg acaagttgct ttagatcgac tggctcgtgt aggaattgat
    20701 gaaatattag caaaaaaaca ggtgaccaaa ctttcgggag gtcagcagca gcgagtcgct
    20761 atcgttcgtg ctatctgctg tgaacatcaa ctaatcgtag cggatgagcc tactggaaat
    20821 ctagatgaaa caacttcaca agatatcgtc aaacttttcc aagaaatcgc ccatgaacaa
    20881 aatcgctgta ttatcatcgt gactcatgag attgaagtag caaaaagctg tgatgaagtc
    20941 tttgaactaa aaaataaaaa atttcaaaaa atcgaagttt aaaaaacagg ataatgatca
    21001 aataaaaaat ccgaaccata tctgtctcgc agatatggtt cggatttttt atttgcttga
    21061 ttcaattagt aataagtggt ttttattttt tttcgtcttt tcgagaaaac ttgtctttga
    21121 cttcgtcgcc taaatttcga gctttttctt tgatgtcagc acctagtgat tgtgctttcc
    21181 cttctgtttc tttgctcttg tcgtctgttg ctttgccgta tgcttctttt ccttcaccga
    21241 ctactttatc tttcatatct ttagaacgtc cttttaaatc tgccattgtg cttcctcctc
    21301 ttagtttgtt tattgatcta ccttcagggt aacatcaaca acagatacag acaaacagaa
    21361 cgctcgtttt ctaaaaaaga tagttagagc tgttgattaa aaactttttt cgaaagtccc
    21421 ccatactttg acttcttttt cttggaccat tatttctcct ttagcgataa ctgtatcaat
    21481 atcaagcgtt tctttatcca agatacacag atctgcatca gcaccaattt cgatttttcc
    21541 ttttttatcc aatttcaata tacgtgctgg attactggtt atagctcgta aggcgatttc
    21601 caaagggata ctttcttttt gcacagcttc tttgatccct actagcaatg ccttggcact
    21661 tcctactcct aaccctagga aatgattgtt ttcatcaaaa taaggcaagc ttccttgtcc
    21721 atctgaggtc atcgtgaaat tatctaaaga aacatcttcc tcgatcaatc gtttcagtgc
    21781 tttgctgaag cgaacttcac catctgtctt ctcccaaaaa tcaggatctt cgctagcagt
    21841 gaagtcaatc gtgccaccac gtttggcaaa tgccacgcaa gcttcaaata attctggtgt
    21901 gcgatttgca tgagtaggca aaaattgtgt gatcggaatt tctgtttctt ctacgattcg
    21961 tgtcaatagc tctagctttc tttttcctcc gcctaagtgg acattgatga tcccagcttt
    22021 tccggataac atgcctccta cacgagcatc tgctactgca cgagcgaact cttcaaaact
    22081 tggctgagaa gaacggtgat cggatactgc gatttctccg attccgataa ttttatcaat
    22141 tgtcaaaaag tctttgatga tagaatctgt tactgttttt accggcaatc ggtacgaacc
    22201 ttcgtataca taagtggaga ttccttctgc ttccagacct ttcgctttgc tgatcaacgc
    22261 agtcatatct ctaccttctc cgtctgttcc caaacaaccg acaactgtcg ttacaccagc
    22321 tgtagtcaat tggctcaatg tgacttctgg cgttcgattt tgataaccgc cttctcctcc
    22381 tccacctaaa atatggaaat gacagtcaat gaaacccggg gttagtactt ttccctcacc
    22441 tgaaagttct tctacttcca ctccttcgta gccgccttct agctgttctt ctacagccaa
    22501 aatcttccca ccggcaatca gtacatccat ttttcctaag taatctggtg caaacacttc
    22561 aatttgtcga atgattttca tacatttttc ctctttcttt aagtataact gatgatagga
    22621 tcttaaaaaa taatccaaac gataggatct ttactccttt gattttaccg taaaatgacg
    22681 gttcttggag tccttatcta ctgtttggat tactttttta tttacaggtc tccagtacta
    22741 ctgcagacct attgcaatgg caatcatgat gaaaatagtt cctaaaacaa acaggaatcc
    22801 ttgcatcttg atttggaatc ttgcccattt tgcccattcg atccgtgcaa cacctagcac
    22861 accaatcaag ctggctgata cgggtgtaaa agcgtccata aaacctgaac caagctgata
    22921 agcaagaact gctacttgtc tggatacacc tactaaatct gccagtggag ccatgattgg
    22981 catagtcaaa gctgcttgtc ctgaatttga tgtaacaacc aagttgaaca aactttggaa
    23041 gatgtacatc gcccaagcac caatgacagc tggaacaccg gtcaacgccg tcccgatccc
    23101 atgcaaaatc gtattcaaag ctgaaggaac agatgcatca gatcctccca agacaagaag
    23161 aatccctttg gccataccta ctacgattgc tgtaccagct aaatcagctg caccagattg
    23221 gaaagaagaa gcgatgtcat tgactttcat tccatctaat ttgaaaagaa cagcaatgat
    23281 tccagcaact aatcccatca caaagaattg agaagcgatt tctggaatgt aatagccttt
    23341 ttgagtcacg ccccaaacga tccagacaag gacaactaac atctctaata agatcaattt
    23401 atgcccaagc atgaattttt tattttcatc agatgtcttt ttgatatgag aacggaaata
    23461 atcatctgat ttgtaagtca acgaactttc tggtttttta cggatttttt ctgcatatat
    23521 catcatataa ccagcggcta atgcagtaac aactacccac ataatcaatc ggaatgtcgc
    23581 accagacaac acggggattc cagcaatccc ttgagccacc gctacgctaa acgggctcat
    23641 ccaagaggtc gcatttccga cttgagatgc gacataagtc acggttactg ctacgatcga
    23701 gtcatatcct aacgcaatga caaatggaac catcaccatt gagaatggaa ttacctcttc
    23761 tgccatcccg aatgtagcgc caccgaatga aaaagcaaag aataatagcg gtaaagctaa
    23821 acgctccagt cccttagttt tactgataaa cgcatagata cctgcgtcga tcgctccggt
    23881 acgcataata ataccaaaag cacctccaac aacaaggatc aatgcagcga tccctacagc
    23941 agatccatac ttatctccag atactagtcc ttcaaaaaca aaatttaaga aaccaaagcc
    24001 gccaaaatca tctgttcccc atattttggc tgttttatgc aattttttag aagtatcata
    24061 gatattttcg ccgtactgat cgtaaagcac atcatctgtc aaggagattt catctagttt
    24121 ttcctgcgta agattttttt ctccgtcagc aatgactttt tccaatcctt tttccggaac
    24181 atccagtttt tcacgttctg ctggatgatc ttgcagttct tctaattgat caaacacata
    24241 cgacttatcc agctcgtaag cataacggaa ggaatcttga cgtaaaacag tacgagtact
    24301 tgtttcgcca tttgcatctt tgtattcaat atcttgcgtg ctgaactttc ctgctggaac
    24361 gacaaaagtc agtatccatg caaagatgac tacaccaaaa ataatgacat acgtatgggg
    24421 tgtcgataat ttagtgaagt cgcgtttcgg ttttcctgaa gaatttgttt tcttcaaatt
    24481 tatttcttcc tttctttttt cagtaatttt gatgaataaa aaatggataa tcaaatgaat
    24541 tatacagtaa aaatgacatt tccacatgaa taatttatta gaaaatcact tttttctatt
    24601 ttgttttttt tctcctatgt atgattattt ttttctcttt ccatttatat taagtatttt
    24661 atttctctgt ttttccttaa aattcttttt ttatttttag attagagaaa atctcgtcct
    24721 gtttttttca ttttacaatc attgaaaaat tgaatttcat tgcaaaaaaa ataataaaca
    24781 cttataaata tccattatct atccttcaat ttttgtgtat tttatttcta ttagaaaaag
    24841 gtatcctgtt ggacaatttt gttatatcag gtaaacttca ttgcaataat gataacaaat
    24901 gtactataat tactttgtaa agagttttgg ggaagactct ttcatcaacg tgtattaaga
    24961 gacaagaaag aatccatatg gattctttct tgtctctttt tccactactt tttatttttc
    25021 tgacactaca tattcttata actcatttct cataactgtg aaacaactta taaaaataac
    25081 aaactttaaa caaaacaagc ttaaaatcaa agatgatcca tcttaaaata actaaaacaa
    25141 aaaaagtagt cgttgttaat cctcattaat aatcgttttc tttttttcaa acgctccatt
    25201 tttatgtgga acattatttt tttaaggaac tttgtcaaca tgtggataac tattttccac
    25261 ttgtgtcctg gactagctgt tttgctgtaa aatacaaaac ttgctgcagc aaaaagatcg
    25321 ttgcaagaga ggctgttccg cagatcgctg gatctagatt tggcaaagtc aagactgcat
    25381 catgtaaatt ggcgtggttg tccaaaacca aatcagcaaa ttcaaataat cgcaaaccac
    25441 tgctatgttg cgatttgata cttcgtgaca aatcaaatcc agtaacaatg attaatggat
    25501 gaccattttc tttgatccac tgagctagtt cgatgattgc cgggtttctt ccttcattcg
    25561 aaagaagaag aaaaatgtct tctgatttga cagaaagctg atcaataatt gcctgtcctg
    25621 caccttctag cgtttcatag acacctccgg ctggattttc aatcaatata cttggtacaa
    25681 gatccggggt ttgatcccaa aattcaaatg ctacaccact tagtgtgcgg ctagcatata
    25741 tctgcaatct accaccttga ttaatttgtt tcgcgatcca agtgccagct tgaagcatca
    25801 gcggctcttc tatccttaat ttctcttcca attggtgata atagtcaaaa taacataaac
    25861 tcatttatct ctcccgccta gctatacttg acatgaatag aaacagctgc ctaatctaag
    25921 gaagtacata aaaaaacagt agttagacag taacacatgt ggtctttgct gtttcaaaca
    25981 caaaaaaggc attgaacgaa tacgcccaat accttgacat agcaaataaa acaacgtgca
    26041 gaccatggaa aatatctaca taggggtaga attttcaccc tagattaggt acaataaatt
    26101 aggtcgatgc actgcattga ctatggcaaa atgatcggtc agggtgtatg tgtgtgactg
    26161 gtcattccct gattcttagc gccaactaag ggtcagggag ccttttttta ttcagctgtt
    26221 tctatctgaa tttattgtaa gtaatctctt atccaagtgc aagcaagaaa atacaaaaaa
    26281 acattggtat gatttatata tatataaata acataaaaaa aggaatggct tatcccgata
    26341 caacaagcat tcctttaaaa aagattcttt tatataagtg aaaaaagctt ttttccacca
    26401 attaaataaa tctctcatct caatagttta tccattattt tatctttttt tgcgtatacc
    26461 tactaaatat taccgtcttc ttctcgttct tctactttgt tcgagagaat ctgtactaga
    26521 aaaagtagtt gtatgtctac cttttctgcc tatccgagac tttcttttca tatatgggat
    26581 ataaatgatt agatacagta cagcaaaaaa taaagcaaat acgcaagctt cccaactacc
    26641 taacgccaat tcaaccatca aggtagcaac cccaacggat gctgcatacc agataaaaat
    26701 cagaaacgtt tctttttttc tgaccatgcg aaacatgata aatagactaa taagcaatag
    26761 tggcaacaca aatatccaat tgcttccttc catcagccac ttgagtatat caagcagcga
    26821 ctgtgcaaca gcgactaatt ttcccatagt gaacacacac ctttttttat aattaaaaaa
    26881 ttcgcctttt tattctacta tgaatcttct ggcttggctt tcatttctct tatgtaatca
    26941 ttttctttta tacaacttaa aaaaaaatta aaccaatagc ataatatttt ctgaatctat
    27001 tcacgaaagt ctttttctat ctttcgtttt ccacgactca actgatctag agtcaaaaaa
    27061 ctaaaacgac agttgcgcaa atgacgcaca agctgccgct ttaataacaa atagcctttc
    27121 attctcagca ggccacttat ttccagttaa ctttctgttc ttagcttttt actcaactgg
    27181 ataatatatg cacttaatga agtcccaatt tccgaatgtt gaagtccata ttcaatattt
    27241 gtcttcatat atcctaactt atcgcctacg tcgtatcttt ttcctttaaa ctctctcgca
    27301 tagaccgcct ctgtctggtt aagagtctga agtgcatccg ttagctgtat ctcgtttcct
    27361 gctcctggtt cttgagtttc taatatctca aatattttag gagtcagtag ataacgtccg
    27421 ataatggcta aattacttgg tgcttttccc atttcaggtt tttctacaaa cccttttact
    27481 ctgcaacgac ccttttcgct atctgtttta ggatcaataa ttccgtattt agatgtttca
    27541 ttttctggta cacgcatgac ggcaacagcg gaagcttgtg tttcttcata atccatcatc
    27601 aattgttgag tcaatgggat atcatctttc atcaaatcat cccccagcat gacgacaaac
    27661 ggttcatttc ctataaatgc ttttgcttga agcacggcat cccccagtcc tcttggatga
    27721 gattgacgga tgaagtgaag attgacttga gtcgtttctt caactaaagc gagtaattct
    27781 gttttttcct tttcccgcaa attgttttcc aattcgatat ttgcatcaaa gtgatcttca
    27841 atgggtcttt tttcttttcc cgttacgatc aagatgtctt cgattcccga atccaatgct
    27901 tcttccacaa taaactggat cgttggttta tccacgattg gaagcatttc ttttgccatg
    27961 gcttttgttg ccggcaaaaa acgtgttcct agcccagcgg caggaatgac tgcttttttg
    28021 accttcactt gct
//
LOCUS       DAPBCF010000034        27888 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.034, whole genome shotgun sequence.
ACCESSION   DAPBCF010000034 DAPBCF010000000
VERSION     DAPBCF010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.034"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(57..173)
                     /locus_tag="RD508_001819"
     CDS             complement(57..173)
                     /locus_tag="RD508_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HDT7736378.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            complement(418..1347)
                     /locus_tag="RD508_001820"
     CDS             complement(418..1347)
                     /locus_tag="RD508_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7736379.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            complement(1364..2386)
                     /locus_tag="RD508_001821"
     CDS             complement(1364..2386)
                     /locus_tag="RD508_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDT7736380.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            complement(2383..4410)
                     /locus_tag="RD508_001822"
     CDS             complement(2383..4410)
                     /locus_tag="RD508_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736381.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            complement(4407..6860)
                     /locus_tag="RD508_001823"
     CDS             complement(4407..6860)
                     /locus_tag="RD508_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7736382.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            complement(6844..7239)
                     /locus_tag="RD508_001824"
     CDS             complement(6844..7239)
                     /locus_tag="RD508_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7736383.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            complement(7311..7949)
                     /locus_tag="RD508_001825"
     CDS             complement(7311..7949)
                     /locus_tag="RD508_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736384.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            complement(8005..8499)
                     /locus_tag="RD508_001826"
     CDS             complement(8005..8499)
                     /locus_tag="RD508_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDT7736385.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            complement(8566..9345)
                     /locus_tag="RD508_001827"
     CDS             complement(8566..9345)
                     /locus_tag="RD508_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HDT7736386.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            complement(9387..9608)
                     /locus_tag="RD508_001828"
     CDS             complement(9387..9608)
                     /locus_tag="RD508_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736387.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            complement(9605..9895)
                     /locus_tag="RD508_001829"
     CDS             complement(9605..9895)
                     /locus_tag="RD508_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736388.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            complement(9892..11076)
                     /locus_tag="RD508_001830"
     CDS             complement(9892..11076)
                     /locus_tag="RD508_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDT7736389.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            complement(11258..12661)
                     /locus_tag="RD508_001831"
     CDS             complement(11258..12661)
                     /locus_tag="RD508_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HDT7736390.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            complement(12683..13456)
                     /locus_tag="RD508_001832"
     CDS             complement(12683..13456)
                     /locus_tag="RD508_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736391.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            complement(13466..13843)
                     /locus_tag="RD508_001833"
     CDS             complement(13466..13843)
                     /locus_tag="RD508_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7736392.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            complement(13864..14178)
                     /locus_tag="RD508_001834"
     CDS             complement(13864..14178)
                     /locus_tag="RD508_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7736393.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            complement(14378..16171)
                     /locus_tag="RD508_001835"
     CDS             complement(14378..16171)
                     /locus_tag="RD508_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDT7736394.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            complement(16168..18357)
                     /locus_tag="RD508_001836"
     CDS             complement(16168..18357)
                     /locus_tag="RD508_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7736395.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            complement(18491..19681)
                     /locus_tag="RD508_001837"
     CDS             complement(18491..19681)
                     /locus_tag="RD508_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HDT7736396.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            complement(20553..22184)
                     /locus_tag="RD508_001838"
     CDS             complement(20553..22184)
                     /locus_tag="RD508_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HDT7736397.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22198..23871)
                     /locus_tag="RD508_001839"
     CDS             complement(22198..23871)
                     /locus_tag="RD508_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HDT7736398.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            complement(23884..24201)
                     /locus_tag="RD508_001840"
     CDS             complement(23884..24201)
                     /locus_tag="RD508_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDT7736399.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            complement(24226..25626)
                     /gene="lacG"
                     /locus_tag="RD508_001841"
     CDS             complement(24226..25626)
                     /gene="lacG"
                     /locus_tag="RD508_001841"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HDT7736400.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            25863..26648
                     /locus_tag="RD508_001842"
     CDS             25863..26648
                     /locus_tag="RD508_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7736401.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            26651..27343
                     /locus_tag="RD508_001843"
     CDS             26651..27343
                     /locus_tag="RD508_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7736402.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(27617..>27888)
                     /locus_tag="RD508_001844"
     CDS             complement(27617..>27888)
                     /locus_tag="RD508_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HDT7736403.1"
                     /translation="SSGISDYIDMSGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDT
                     YLVGKLINILGTEKDTETFISSLSMLFTDKHFSTQLGGEELVEIF"
BASE COUNT         8402 a         5607 c         4624 g         9255 t
ORIGIN      
        1 gcatcaacat gagctaaaac tccaatatta ataattttca tgtgattttc ctccattcaa
       61 aaacccaaaa gggcataaaa atcccagtga taaatacttt tatcactggg atttttatgc
      121 ataaccatag gtatacaaag catacagata ttctctggat actttagaat cacatgataa
      181 aggtattctt aaactgggta caaaaaacta agccctccta aaaaaggaca tctaattatt
      241 tgttcccgct atcaaattga cagtttattt aagaatacct tgccgcatat ttattaactc
      301 cttttaaata gtcacttaaa taatagcacg taagagcata tttgtaaagg aatctccaat
      361 tttttatcaa aaagagtaca tgattacaaa gtatctgtaa tcatgtacca atatttgtta
      421 ttttacaatc ttccaattat cttgtttttc taatatcaac tcaaattgcg agatttgggt
      481 tgcctttgtt tcttgatcta aatatttcac agcgacattc acgattactt ggttatcttt
      541 tctggtaaag ataggattca ccaattcctc gaaaacatat tccttgttaa tcataggtaa
      601 cacatgatta cttacatagt aagtcaattc tttttctgtg gcggtaggat agagctggaa
      661 gaacgtttct aaaaagctag tgatttcgtc catcgtttct gtatctactg tatggtcact
      721 ttctagctgt ttgggttggt agtccgattt ttgaggtttc ttactcattg tcggattttt
      781 gataataacc atattatctg attcatctat atggacaacc acatgaaagc tagacgatat
      841 agtttccttg tctttgtctt cggtaataac ttgttcaaca gaaaacagta cctcaaaggt
      901 gttctcattc acttgagaaa cctgccacac ctgtatatcg ttcacactag aactagtagg
      961 aatatcctta cgaatcattt cttcatttaa tacctgcaat tcttccgtca aataatgggt
     1021 caatttttca tttcgtttat caatggcttc ttgggattgt tgccacgaaa agtagtcttt
     1081 cgcaaaggat ttcacaaaac tttctacttg gttggtatcg acaatctgct gtttaatgat
     1141 ttctgtttca cggacagtat gagtgtcaat ggcagtaaaa tttttataga ttccaaatcc
     1201 gacactacca atcaataaaa cccataaaac aaaggttaat ttcttatgcg tgccaacttt
     1261 aatcatcgga acttttcttt gcttgctcgg ttttttagat ttctttggtt tctccttctt
     1321 ttcttttcgc tcgattttta taatcatttg attcattcct ttcttagtta tgaataacac
     1381 gtctagcccc aatcagatgg tcttgccaat aacgactgct taagtcgcca taaccgattg
     1441 ggtcgcctgc atgataaaag cgatttccct ctaaatatat cgccacatga gtcacatatg
     1501 tgcctgcatt ataggttgaa tgaaagaaga taaggtcgcc tgcttgggct tcttccatag
     1561 agatttcttg cgtagcgtca tactgatctt gggcgacacg agggagagaa atgccagctt
     1621 tgtcatacac ccattgtatt aagccactac aatcaaaaga ggtggtaggc gacgcccctc
     1681 caaagacata gggaaaccct tcgtatttca aggcttcgtc cataatgact tgcacggttt
     1741 catcatcaaa ttctgttggg gaagtgtcgg ttaggtattg tgaaaccaac tgaacataaa
     1801 actgatttcc atagttatat cgccaaccac cattcacagg tatggctata ggattgggat
     1861 agtctgcttt ttgaccaccc gacttctctt tagaaaactg ttcggctaat tcataggtat
     1921 attttttccc atgactcctc acataattta aaaagccacc gccataatta taagattgga
     1981 taacagaatc tatatccact ccttgttgtt ctgcactggt taataattca ctgaaatatt
     2041 taaccccttg tttgatggac tcttcggtac tcaaactgtt gggcggtaaa cccaaagatt
     2101 cggaactttg cataacatct tctgctgtac cgcccgattc cacttgcata atggctaaga
     2161 tataagaaac atagtcttca atcccatatt ccttaccata tttttcaatc aacggacggt
     2221 gtgccaacac ttctggtgaa acggtcacac cgccttgtgg aatagaagaa tccttgttgt
     2281 tttcgccact gtccgtatca tctgcaaaga aaatgactag gaataataag agaaaaaaga
     2341 agagagagaa gaccacacta caaatcactg ttatttttag cttcatgttt gttgtcctcg
     2401 cttatccgtt cttttattta gcttcctctg attgaattgc ttcggtggtg tcttttgttt
     2461 ttgctctttt ttcaatggtc gctgatgatt ttcacgttta gtgttttgtg acaaaacagg
     2521 cgtgacggtt tgctgacgct tgcgaacatg ctgctggtta ttctgaacag gagatgatgg
     2581 gttttctttt cgtctttttt cttttgcttt atccagctcc aaacgctttt gagcaatgtt
     2641 ctttcgtttt tgctcctgct ggttcatacg ctgttgtttg cgttgagctt tggtatctgc
     2701 catagattgt ttaaagtctg ttacattatg agtgacattc tcttttcctt gatgaagggc
     2761 atatttgaca tgggttggtg tcgcctgtat ctgttgtttt gcctgctttc ttttattgac
     2821 tagacgattt ttcgtgtcca atacatgggc tgtcttttca cctaatcgtt gcccgatacc
     2881 gccttgttgc tttttcacat tggaaagtgc tgtttctttc tttggtgtag tccgttcatt
     2941 ttgacgagta tggttagctt tattggtttg attctgcttt gttgtcattg tcttttgctt
     3001 cgttgaccct gcttttccac gaaaaatctt actcatactg cgttgaaatc ttctggtttg
     3061 tcgattcatc atttgacgag gtctgcgaaa cacttgtctg cccatgtttt gagagtcgtt
     3121 gctttgtaaa gtgaataggc tcattaaatc gcccagttta aaataaatcc ctgcaaaggt
     3181 cacaatttgt aaaaacataa tcatgaaaaa gggagaactt gctgacagcg aataaagcat
     3241 agtggaaata ctaaaggcaa cggtaataat caaggtaata ccagcccttg tcataatcac
     3301 attaaataac ttggtaatgg catgcctgcc catgccatca aaactcggca acatacttaa
     3361 taggaaactg attggcaaaa acatagcgaa aataataaat agcacttgcg aaaaaatcat
     3421 gattcctgtt agaaggaaaa caaaaatcga gataccaata ttgaatacaa acaaaaagaa
     3481 gactgttcct aatctggaaa tcgtcttcgg tagggttaaa taggtattgt catgatcttc
     3541 aatttcttca atcactacat tttctctatc ttcaccattg tttgtatctg gactggtaga
     3601 caataaactt tccacacgtt cttcccctaa cgcttctaca tcagtggagc catattgaag
     3661 caatagccat ggttgcttta cttgaacaga gaataagctg tcacgtatca tgtccacact
     3721 gtctttccct tgactatccg tgttaggaag aacaattttt gtcccaatat tcagactggc
     3781 ggtactgaca tctttggaaa aatcattgat tttcgcaata taatcgggtg catacgcaat
     3841 aaaggaagcc gatagaataa acaccacgac aaagtttaaa acagctcgta tcactttcgt
     3901 cgtttctcgc ttaaccaatc ctgtataggc aacatagatt ccaacaatga gaataaaaag
     3961 aaggaggaaa ccgacataaa accctgaact ggaaaagcca ttcggtgtaa tgcctgcaat
     4021 cgtctgcatg ttttcgccaa ttgcttggga tgtttgacta atgaaatcta aggcataggc
     4081 ttctttcacc aaataacctg tggcgttcga tagataaaga gaaattgtcc aaataaaatt
     4141 agtaatggca tacaatccat acatcaccga ttgtcctatg ccatcactcc aattccatgg
     4201 aagccagccc cagctattgt ccacataata atcaagctga tattgattca aaccatactt
     4261 ggagtattca ttgcttgtat caatggtttc atcaactaag cctgtcgctt gtactgcatt
     4321 gcccagcgtg cctaataaaa gtaaaataac gcccacacaa aggagcgtta tccaactata
     4381 gtgaagaaat ttcttttgtt tttgtgtcat tcttccacct catttcgcac aggcggtctg
     4441 gtatcaaagg catgaagcaa ctcttcaaaa atcgggtgaa actgcataac ccctacacga
     4501 ccatagatgt ctgaaactaa acattgtcca ttttctaatt cacgtaagcg tttctgattg
     4561 ttttcatctt ccttgtccac accaaaaaat tctaaggtct ttttgatttc cactaggtca
     4621 gtggaacgaa aggcaaattt caagccaata ttattcttca tcttttcatc tagtaaatcg
     4681 tccgcgtttt gagtaacgaa atagacccct gcattcatgg cacgtcctgc tcgaaccaat
     4741 cgcatagata gagcttttcc ttgtgccact tgtaaaaaac tccaagcctc atcaaggtca
     4801 acaattttaa aaatggaacg gtcagagtgg ataaagtcta aagcaaaggt actaatgaca
     4861 atcagcattg ccacacttaa taattccatg gtagtgtatt cttcaaaaga gctattggaa
     4921 tcgggtaaga ccaaatctgc cacttgaata atattgagtt gtttttccaa gctaatggat
     4981 tgggtgacac tgccatcact gaataacaga tgggcaaaat cataatcgac aaagctttcg
     5041 atatggtcag caatactatt gctgatgggc gtatcttctt ttcgcaattc atcaatcacc
     5101 aataacaacc ctcgttgttt gctttgagtt acactccgaa tagctttacg caggacagga
     5161 aacttctcgc tatctcggct ggaaatacct gttaagaacg tgagaatatc aatggcaagg
     5221 ctttctgaat ctttcgggag ttttaaaatc acataagggt caagtaaccc tttattgtcg
     5281 ttctcactcg tgagattaac aatattgatt tcatgggcaa tatcaggtaa ggtttctttc
     5341 cattcaccac gttcagcttt tgggtcaaca atggttgcct gtccgccaaa gagtactgaa
     5401 taatagacca gcatattgtt agagaatgat tttccgccac ctaatgaacc aataaaagcg
     5461 gacgctaatg catttgttac agagccttta attccttgac ttgcaaggct aggttggaga
     5521 taaatatttc tgcctgtatc gagattgtaa ccgacgtaaa taccagaatt ttcaccaatc
     5581 atttgtgtag caccgaaacc aagaccagcc aaaaaatccg acgtgacata ttgaatatag
     5641 tcattgatat atcgcttgct tgagggaata aattcattat gcaagcctag catatcgcca
     5701 aaaggtcgta ctaatttgat agacagatca tcataaaaat cttttacttc atcacaacgt
     5761 tgtttcagct cgtccaaatt ctttgctgat acccgtacca catagcttag tttgtacata
     5821 gattctttgg tttggtctaa attactttct aattcatcga cagattctaa agcgtccacc
     5881 acattagtac tggtttcgtt gtcgctttcc catgcgtggc tatctaaatc tttcagttct
     5941 ttctttttat tgcgaacggt agataaggct tttttattgg cgacaatttc aacattcata
     6001 ctggtatcaa cggggaaagt aaactgctgt tgctggtaat aaaaaatttc actattaggg
     6061 aaatccaatt caccaacaat actattaatt gtaaaatacg ccacataagt agtggtatct
     6121 tcctgttcaa tccgtaaata gcgttgattt tcttcgatta aacagcgagt gggtttgaga
     6181 atatcgtatt tctttaccaa cactttttta tcttcgtatc gtttcggtaa atggtagtcg
     6241 tagtcatcaa aagggacacc tgtttgcccg taaagatgtt caataatata accaaaatca
     6301 tctttctcca atttacgaat ctgaaagcgt ctggataatt tactttctaa caactgttcc
     6361 atcttagaaa agcgttcgat ttccgccata ggcatagaaa caaaatcgcc cattaatttg
     6421 tgattcacac catgaaagaa ttccgcaaat gctttttgaa tttctttccc aacatttttt
     6481 acggatactt cctgttcatt gaggtagagt ttaaaaccaa taaaaaagcg atagtctact
     6541 tgattgtcac caatcataga aattaacgct tcggtctgtt catctatttt ttcgtaagct
     6601 atctctttta atcgtccagt gatttctttt ttcgattgtt cctgtgtggc tcgaatactt
     6661 gattcggttg ctagttgcag agcatgaatc ttgccatcac gattttgggc aatcaattga
     6721 cagaaattat catgaacttg aattttttca tcggaactta aaaaactgta attataggga
     6781 attaattcat aataagcgaa tacttcgcca tcatgattaa atacgagatt atcttccata
     6841 tatttaatcg gatatgccat ctagttgttc actccttaca atcgtaatcg attcattcat
     6901 tgtttctttt tttaatcgta tttgtttgcc agcgtaggtt actttagggc gtagagcata
     6961 ggtaatgata gactttagaa atccataggg tttctttccg tcaaaggtct tttggcacat
     7021 gaacccagtg agaacaatgg gaatccctaa gtatttgagt agtgctccgt caatcagaga
     7081 aagtggtggt aaactgccaa agagtatgac gacaaacaaa gaaacgataa accatgtcat
     7141 ttgcgtaaag gtaattggga aagggagttg taaatcatta atcgcataaa tcactttttc
     7201 tactgaccaa atactggtgt aacttcttat ttttttcatg tcttcacgtc ctttccgtaa
     7261 aaatagaaaa agaacaatca aaataggtga ttgctctttc aatgctttaa ctattcaatt
     7321 ttattttttg tccattttgc aataatacct tcatcagttt cttcatcatc tggattcatt
     7381 gaatatctga aacttaaatt ggtatctgac cctaatcgtt catataagct gggtctatac
     7441 aatctcgttt tattgtcatt aaaaggactt cgttttccca gctcaccatt tccctttaaa
     7501 ggatttcttc taactgaaaa acaatatttt tttctgggat cttctgaatc actttgactt
     7561 aatgagaaac acatggcttc tttttggtct tcatttttct tctcactaac ttctgtcgga
     7621 ataaatcgag caagagtttg gctaaattga aataaaacat ctcccaagtt actactgtat
     7681 tcgataccaa aatattctct tattgttttc gtgtctgtat ataattttac cgaattagca
     7741 tagacagcta gcatatctga aaaatcgttt tcctttaaaa attctagttt taacagagca
     7801 tattctggaa ctttttcctc tttttcaaat agcttaacaa gtacaatata attttgctgt
     7861 ttgtaacgaa agtaaaagga atctatcacc cagcctttat ctttcatgtc tagttttaat
     7921 agtttaagat tttcaaatac atttaccata atttatacct ctccgtgcta tttattaatt
     7981 taattataac acggattgtt aaacttactg acaatattca aataccccat gagaggtaac
     8041 taggtaatta ccctctattt ccatatcacg tcccaaagat tggtagtcaa tataattttg
     8101 taaattggaa gggacttcac caagctgtcc tgtttcttcc acgtaataac gggcgacatc
     8161 ttccatcgaa tcacaatcac tataacaatg aatatcctct ttgttttcca gtaattcttc
     8221 caagctacta aaccacatgc cttgaatttc tttgagttca ttataaatag gtgtaccttc
     8281 gatttcttga atggcttcac atagacggtt gatttcacta atcggcgtgt attcgtccac
     8341 atcaaaagga agctcaaaat catgtattgc atattcttcg tagtcctcat ttaaaccgat
     8401 tctttctgcc atttcttcct catcaattgg tggagtaaac catgctccga ctaattcacc
     8461 ttcattatac cgtcctaaat ttgccacata gactttcatt tccaattctt atcacatcct
     8521 ttttataaaa atagtcataa aaaaagtagc aatcagttaa tgacgctact tatcaaggta
     8581 tccgctaata taatctgtaa ctgtacttga aatacctatt attagttttg cttctctctt
     8641 tccaataata tttgtattag ggtgtgcaag tgaatgccta tttcttgctt cattaagaga
     8701 gctaatcatt ccatttgatg accttatcgt tgtcttcact atatcagcaa gttcagtagg
     8761 ttgaatttct ttttcaatta attgttgtat cctactatat aatttagata gattttcgtc
     8821 tctaggaact gtaatttcat atttttttag tatttcaatt aaatatccat gaaaagcagt
     8881 gtgaactctg tcaaaggcac gttgatattc accattactc ataaaagact cagcgtcttc
     8941 aatagcttgt gaaaccacat cactaatttt caactgacta aagttaatta cttcgtaatt
     9001 ctctggaagt ggtactaaaa tagtatccac taatacatta tcaccttgtt tatcatatat
     9061 ggagcttgct gtctgggtaa tcaaatcttt atgactttca aaaaagtcta aatcatcaaa
     9121 aggaactctt attttaagat atgtgcaaag cgtattccag ccctttttat atcctttata
     9181 ataagtaaaa tcgtcagtct catctaaagt tacctctgat attttcattt tagaaacaat
     9241 ctcgttacct ccttcataat aatttgaaga gctctttctt tctaatgttt taattaaaag
     9301 agatttaaat tgatcatttg taaacatatt cataaatcct ttcataacaa aatatatact
     9361 tcctatttta tcatgaaaaa tatctgttaa gcaccaatga ttcggttaaa taagtttaat
     9421 aacacatctt tcacgccagc tgcattgaac acaagtccga cggcgattag agcaataatc
     9481 aagaagccaa tgagttttga aaattctcgt ttaaaaccta aaaacagtcc aatgacaaca
     9541 atcgctaaca ataccaatga ctgtgcatta tccaagaacc agttgtacaa attctgccca
     9601 aaattcatgt gattgtcctc ctttccttaa gatatttttc tcgataatag atatagcttt
     9661 ttacacgcct taataattga aaaggggtta aatgctctcc atagacggtt actcgattgg
     9721 tataattatt ataaaatctc accttgtaaa aatcataggt atagatggta tcaccagctt
     9781 gccgttttcc ctcaataatg agagacgtat atttccctgt attttgtata tacgcttgaa
     9841 actcaatgcc acactgaaac cctaacttct ttaattcttt tgttaaaagg ctcatgtaat
     9901 caaatcctcc atggctagat gttgttgttc aattaatttc tcatgttttt ctgtcagttt
     9961 ggcttcctga atcatggtgg agataatggt tgtaccgttg agaacatcta aaatgcttgc
    10021 gatttttaat gtaggggcga cttgatgatg taaccagttc aatgttcgtt caaaagaata
    10081 aggctctggc tgtgtggtta ggcgtaatgc tccacgattt ttaccgataa accattccca
    10141 acgttcatta gttttccaat cactccgacg tttagtgtcg tctttatctg caaagcggat
    10201 atagcgattg ataatttcaa aggctgtttt ttccgcctgt tgatgtgcca ataaatcttt
    10261 catggcttgg gtggctcggt cattttttaa ccgaatttca aaccgattct ttacttctgc
    10321 gtcttctaag ggaacatcat ttttcacgta ttgctcataa tctttctcat atatacagaa
    10381 atagacttca ctttttaatg agccaatata aagtgtgttt cccatgtatg gtttttcatc
    10441 acggtgaacc aattcaccac tgcgataatt tttaaagctt cgaaagacgg aaatgcattc
    10501 ttcctgttta catttctttg ccaaatctgg aatattcaaa atccctgttt tatcgttgat
    10561 agctaaatcc aagcgtttga aaataccttt atgttccatg caatcttgaa agaaatcata
    10621 ccagctccga tgttgagcca atagaaagtt ttcaaattgc cgacagcctt ttcctttcag
    10681 ttctaataaa acacctttac ttacatcatg agagactagg acaacaatat caccgaaacg
    10741 atagtgttcg ggataagaat aatagccaaa gtcttcgtgt agcatataat ccatattcaa
    10801 acgtaaaacc tcaccgataa tttgagccac atcattggta gggaatcgaa tccgtacata
    10861 gtcgaataac atctccaatg ggttatcggg attgaagcgt tccaaagcgt tcagtaaatc
    10921 ttctttcacc tgttgagtag ggactgcctt gcctgtttca atatccgata ggtaaggtct
    10981 ggtaatatga gaagcaaccg ccagtttatt ttgagaaacg ccataagcca gtcgcttttc
    11041 tttcaattcc ttaatccaaa ttttttcgtt ttccattcgc aaacctccaa tctaaaaaag
    11101 atgtaaacta tgacccttga gtttacacct ttcatatttt ccgcaatcct ttgtaccatc
    11161 aacattggtt gatgagaatt gcctgttttc agttgtattt gtgcccccct gttagataga
    11221 gggggctaaa ggattggcgt ggctaacgcc acaccaatca aagcaagtct gaacctgtac
    11281 ctttcacttc gtgcggtaca ggctcagatt gctttttttg aatgactttt cctatttctc
    11341 ctaagaaatc gtaccttttt ggtacaaggg gtgtataaaa ctcactaatc acactttttc
    11401 ctgtatccac gtaacctctt cccttgatgg gttttaagaa aaattgtttt tgtgtatcgc
    11461 ttccgaacat cataccaaag cccatttcag acatacgacc caaagccaca cggaagttaa
    11521 agttgtcccg aatcccatca ctaaaatatt ttgcgtctgg acgttgacag gcaagaatta
    11581 aaaagaagcc tgcttgtcgt cctaacatta caatttgttt gagtttatga ataacggtgg
    11641 tactttcacg acctagcata tccatcattg ccacatattc atcaaaaata agaaaattgg
    11701 cagacaaacc aagataagca taattttctc ctgttttata gttagggtgt tgtttcatgg
    11761 tttcactgcg atcaatcata tcttcgtaaa attgattgat acatgccaac atatcttctt
    11821 tacggtaata gacattattc atgaccgccc ctaagtctgc caaatcagca tttttagggt
    11881 caagaatata aagctttgca tttgtatgca ggagagattc aatcaatgtg agaataaaat
    11941 aggattttcc actaccagtg cccccagcaa ttaacatgtg agggagagaa tcgaactccc
    12001 aatagaccga ttccatcaat ttgacacgtc catcttgagc taccacgtct tcaatgccaa
    12061 ttcgattgcc aatagtatca taaagtagga catactctac ataagaatct ttcaacgttt
    12121 tttccactaa ttcacaatac aatcctgttt ctagtttgtt ttctaggtgc aaaagctgat
    12181 cttgatattt ccctaaggtg atttctacat gaatatggat tagtccatct ttcattcgat
    12241 aatatatttt aggaaaatgg cggattcgtt gtttggtttt cttgctgggt aaatctttaa
    12301 agaatccctc tgattgagtt tcttcggctt cataccaatg attttctaaa atcatacgag
    12361 ctaacttttg acggtgctct aactgtttta tagaatctat acgatagtga taataaagcc
    12421 agctgataag tccgcataca aaaagagcag tgagaatact gctccaaaag tatggcgtat
    12481 gaagttgata gaaaaatgta tctaactgaa ctgcttgcca gttcaccgat tgtaacgctc
    12541 tccaatgaaa agggagtagg acgactagaa aaactaccag caatgaaatt agtacaaaat
    12601 gatagaccaa gtgcttatcg ttggctttga ttcgctctcc tctgtcatga agcaatggca
    12661 taaaaatcct cctttccacc tatcaaaata attgtgtatt gtagatacga gcctgtttat
    12721 caaaagttgg ttgagaaata gcttcatatt tctgataagc gattcgcttt tcaaagcgta
    12781 aatttttttc tttcggataa taatgacgtc gatagagagt gtgtcctaac agttttttcg
    12841 cttcttttgt caacggatag agatagcgaa acatgcgtcc attgattttc tcaatccctt
    12901 tgtattcgca aaatgcctgg gaaagccaat gctttttctc tacctgttca aagcgagcat
    12961 tttcctctaa taaaaggcga gcacttcgag ggtgtatctt ttcccatgac tgcttatcac
    13021 gatagacact tgtcttgaaa tacccgcagt aaaagaagtt ggacgcttga tagacatagc
    13081 cacattttcc ctcaattcca tctgccagtg tatataaaaa atgacagtcc gtatgttctt
    13141 tcaaccactt aattagagct gaaagagctt gactgccaaa ataattggtt tgattcattt
    13201 ctggaagaaa acacatcttt ccaatttcta aataatctgt ggtttgaagg gaactgtcgg
    13261 gaaagagttt gcgtatggtt tgtaggggtt gcgtacccca gcctaattcc acaacgccta
    13321 ataatttttc ttctgaaaaa atccctagaa agtatttaca caatctaggg agtatctttg
    13381 aataatggta ttgccgaata aaagaaatgg cttcatcctt cggaatttct ttcaaaatca
    13441 atggtgtgtt tgtcataagc aacacctatt tttcactttc ggacgcttct tttttatatt
    13501 tctgatgagg ttttgtctgt ccttttaata caagatcgtc tgctttcacg taccaatcaa
    13561 cgtctgcccc tcgaaaagta gccgtcgcta cggtatctgc cacaggattg attaattcca
    13621 cttctgcgtt gtagtcaaat tctttcaaag gaacagaagc ggggatactg acttgtatca
    13681 tgcgtccttg tccttttgat tttaagtcat aggtacgttc tttaatttct tcggaaaccg
    13741 taccatcttc attctggata cgaacctcac gacgcaaggc ggaaaatttc aatgtgccaa
    13801 atgtctggtc tttttcaatc acaatacctt ctgctaatct catatttttt cacctttcct
    13861 ttcttatgct ttcaccatat cgtctgcgtg cataatgtaa ttggtaaatc ctcgattgcc
    13921 aattttataa ccttctgcgg taatatgtgg gttgatgagt ttgacttttt cgtcggattc
    13981 aaaatgtttc tcgccagctt cggagggaag aatgacaaca atatcatctg ctcgttgaat
    14041 cgttgagtat aaattgtaac tacgagagag aatggttggt ctgccattta ttcgacgttg
    14101 ttcaatgttc ccttcaccag catattctaa ttgtccaaat gttttttcca tattgggaat
    14161 gacatattta agttccatat ttttacctat cctttctgtt tttatgtttg aatgaatctt
    14221 atttgtgtga tggttttaaa ggggggagag cgaccttttg attcttgatt ttttattttc
    14281 ataagttcac ttcctttcaa aattgggtaa aaaaatagac gctccgtact gagcgtccga
    14341 ttcctactat atttaaaaca acgactacct aggtatttta aatattataa tcaaattcta
    14401 ttttatctaa taattgagtg ggataaagca agtctccttt actcgtaaaa taacccacct
    14461 ctgagaaaag aaataaatta ttttttgctc ttgaacaaat tacgtatagt agttttctcg
    14521 ctgaactaat tcctttatca gaaacattaa aaatttcatt ccaatgagga attttcccgt
    14581 ttagaagatt aatagcgata acagtatcat actcatttcc tttaacttta tgtgctgtag
    14641 taagtgtgat accatctcga gatttaaaca tcttcttaaa actagataca ctactagata
    14701 atgaattatt ttttatccga tcttctactt cgttaataaa aaatagatag tgcttaaaaa
    14761 tagacgggta atttttctcg tcaatattaa gattaacaaa tatatgtttg gtaacaaatt
    14821 tgtataaatc aacaccgttg tcgtctccac tatacattct tttcacactg tttattagct
    14881 gtaataaatc taagtcaata aaataatctt taacttctat tccaaattca ttttttaata
    14941 taattaaaat atcgtttgca attagctttc ttcttcgaac cttttcacct gattcagtaa
    15001 agtacaaaat tgctaacttg aaaaataaac tatgattatt taccttaatt ggtgatatat
    15061 ttatagcatc aaaattgcaa tacggtaatt ctttctttaa atactcaccc agtgaaaaca
    15121 gaggatagtg ttgaggagca agtacacaaa tatctttttc atgaatgccg ctttcaatct
    15181 tttcctttat tatatttttt attatgttgg gtaaatcctc cttagtaact ttgcaatcat
    15241 aacttataaa accacggtcg tttttattat tccctctgct ttcaatctcg taaggacaac
    15301 tctgaaaatt agagtagaag tctactaatc tctgattaga cctgtaacag ccatgtagcg
    15361 tctttgattg aaaagtgtga ctagttagca tttctagttc ttcaactgat ttagctatac
    15421 catctaatga tccataaatt gcttggtcaa tatctccaac aaacattgac tgaatttgag
    15481 ggttgttttg aagtaattta gctattacat tgtattgtaa ttctctagta tcttgaaatt
    15541 catccacata aatcgccctt atattactag caatattacg tgcaacgtta ctgtttacag
    15601 ttaaaatttt atacgctact agtaaaatca tatcaaaatc aatttcttta tttttttcca
    15661 acatagtgtg atacatttca gaaacttgag tatactgaac ttcattaatt ttaaaatcat
    15721 gagaaagtga caaatcaatt ttgttcagtt catacgtttt gagatttaaa ttcagcatat
    15781 tattaatttg gctgacgtaa gctctttgag tataatcatc aataattgta aatccttttg
    15841 atactcttga gagattcatt ttaaaaggat aaataataaa ttcaagacaa aactgatgta
    15901 ttgtccccac ccaaatatta atatcatcat ctatactaag taaacttagg cgttccttaa
    15961 tttcttcagc agctctatta gtgtatgtga tagcaattat tctttttagt gatccatcgt
    16021 gtttaattgc ttggtaagca attttccttg taagtaccct tgttttccca ctcccaggac
    16081 atgcatttac ataaaggtta tcttcacttt ccacaacatc tttttgttct aaatttaaat
    16141 catttacgat tttttcgaag atatttgtca ttttgaaacc tcagcataaa gtatttttgt
    16201 gtaattttct atctgattga ttagatacac aacatcctca tctttaccaa agtactctaa
    16261 taaagaaatt attgctatat tcaaatcagc tgtatcactt gtttttaaac tagctgataa
    16321 agctgacaat tctgtagttt cctcgtacaa gtcgattgta tggagtagaa tttttttata
    16381 aattgagaga tctactattt cctgacatgc aaaagcaata gcattaagaa tatacttagg
    16441 aattttgatt aaaaagtcaa ttttttcacc taactcaatt gcaaaccacc ccttaccaac
    16501 atgattggct agttttaaca tcgctaaatt tctttctaaa tattgttcac tttgtatttc
    16561 ttctttataa gcagttattg tttttttatc tttgaatgcg tcatctataa ttggactgac
    16621 ataagttaga atattttctt tattcacatc taaaaactca atttcaaatg ttgtattagc
    16681 ataaaaacaa ttaacccaat tgttttcatt aaaaagggag gataattttt cttttcttgc
    16741 ttgacctttc tcttgtgcag tgcttttata caatcgatgt tctgatggga ttgcctgttc
    16801 atctaaatca gttacaatag cacactttct ctgtattcta tcatcgtcaa acaagctagc
    16861 gatatattca aacgaagtac taccaacatt aatcaaacct attccaagtt cgtctaagtt
    16921 tataccaaat aattttttta ctatttgagg aataagtatt tcttcagcat ctccttcaac
    16981 taagataaca cctttagaaa aaagcaatcc atttctttta acatctaaat atctctctac
    17041 tgcgtttatt agatttagat tgttcttttt taacttttct ttagcaaatg agttcagatt
    17101 atttgctgga ttcataacga tagatttgcc attaaacgat tttaatacat tcatccgaga
    17161 tatttcagac acttcagcta aatgtacaga atgtgtggtc atgagaatct gagtatagtt
    17221 tttttgaaga tttaatcctt cgaacagagt tttttgaata tgatgatgaa tatgagcttc
    17281 tggttcttca atcaacataa tattaagtag ttctcttgaa cgacacgctt caaattcgac
    17341 tattttcaaa gctaaataaa tcatatttag atgtcctaac cctagtaagt ctaagtcgat
    17401 attttgttct ggcttcattg aaagaaattt tgctaaagaa cccatatcat ctgacatagt
    17461 tgaggaaaga agaagattag gagaatacac tgaaccaatt atgctattta gttgccgatt
    17521 aatattttcg ccaattttcc taatttcagg aacactggta atagtctcat ttaattgctg
    17581 tataattgtt tttaatgact caacattatc tgatgatatt tttgattcaa ttgtttccat
    17641 gattcttttg actgggtttc gattgttttt catttctcta agaacatctc gaagagcgtc
    17701 aacataaaca accgaaatat gcttgaaaat atctgacatg tcaattcttg agcccaacag
    17761 agcttcatcg tcttcttcag gattactagc tatattgtca ttgagtcttc ctaccaattt
    17821 atcataattt tcattgatac agaaatttag atttgattta gatgtgtagt aaaattcata
    17881 gtcggataga cgaatagaat ttctaaattc gttaaattga tgagagtcta attcagtgga
    17941 aatatcaaat aattgctttc taatagcttt gttaggtcta ataaatagag aaatactacc
    18001 tacaccttta tctgcatttg aaatcaattc ttctaagatt gtttgacttt cagaatttaa
    18061 agaaatggaa gcacaaatct cattgtcaaa ttcttcttcg ctgattcctt caaatgtcgc
    18121 agagataata atccaatgcc cttgccaccc attttgaatt ccatgaaaaa aatctgattc
    18181 ttttagtgtt ttactactat agtaataact atcatctaat aagattctca atgcagtaag
    18241 agcattggtt ttccctgaat cattctcacc tataatagta tttgtctcat tatcgaatcg
    18301 aaagatttcg gattcataat ttctaaaatt tcgaatttga agagtagata taaacataag
    18361 cagatctcct aactatttaa ttaatatgat tatatagtaa gtttatcata aattatgtta
    18421 gtaaaagttc tcattataag ggagcgtcaa taattttgtg taaatgattc ttccctactg
    18481 cagattgttt ctaattctca atcagttggc ttagcatttg ttcgagctcg ccttcggcct
    18541 gttggaaacc tttatgactg cgacctagga atttttggtt gtaagtatca aaagacgaga
    18601 ctaagaaacg ttccatcgac tcttcatttt ggaactgttc cttgcggtgg ctgtatttct
    18661 tgatttgttt attaaaggat tcaatcaagt tcgtagaata aatactcttg cgtatggcca
    18721 aggggaaatc atagaaagtg agcaagtgat cgttcgaaag aatcgattca accacttttg
    18781 gatagctggt tttccatttt tccgcaaaag taccacgtgc ttccaacgcc acctctttag
    18841 atgaggcttg atacaccatt ttaaaatcat cacagacttc cttacgatca tcgacacgca
    18901 ctttatgact gatattacgg gaaacgtgta cacaacaatg ttgaaaacga gctttgggat
    18961 agaaccgact aatcgctcct accatcccct ttaagccatc cgtgatgaac aggaggacat
    19021 ttttcaaacc gcgctcttga aggtccaata aaatttcctc ccaaatcgtg atggattcag
    19081 tcggtgcaat cgcatagctc aatacttcct ttgatccgtc cgggcgaatg ccaactgcga
    19141 tatgaatagc ttccttggcg acggttttcc gctttaacgg aatatacgtt gcgtccatat
    19201 aaatagcagc ataacggtca tgaagctccc gcccattaaa cgccgttacc tcttctgtaa
    19261 atgattttgt tatattggac atggtttggg gcgtgtagta atgcccatac attttctcaa
    19321 tcaagtctgc gatttccgac atggtaatac cttttcggaa gaggtgaatg acggtctcct
    19381 ctaacgtgtc attcgtccgt ctataagcag gaacagtctg ttgcttgaac tcaccattgc
    19441 ggtcgcgcgg aatctggaga tgaagttccc catactcggt cttgaccgta cggtcatagg
    19501 agccgttacg agaattaccc gtgttaaaac caatgcgatc atacttttcg taatctagga
    19561 aagccgttaa ctccgttttg agaagcgtat tgactgcttt ctccaaatgg acacggaata
    19621 attcattcaa atcgcctttg ttcgctagag tctttagaat ttctgtagta aaatcgttca
    19681 tagggaagtc ctctcttctg tgaatgtgtt gtggtaactc tattctacag aagggacttc
    19741 cttttttcta tttacacaaa atattttaca ctctccatta taacaattgg gttaaaaaga
    19801 aaatagatag tattctacct catatttatt tgaaagtaat atataaaaga cgttcaaatt
    19861 cgaacgcctc tcgttaacca aatattggat tcagaatcta gttttcatat ataaacagag
    19921 tatgattagg tgcaaaaatt gcacttttat tgcactttta tttttattta tagtgtttta
    19981 ctgttctgta tattgtttta actcccttga tagtatcgca ttctgtttta tacactttac
    20041 gttgaaaaca gagtgggaat aaagagccaa cataatatgg agggggaatc cctataaatc
    20101 aacattcttc aatagctaaa atgcttgatt ttcattaaaa ataagatggt tccctaccaa
    20161 aagagactat aatataagtt aatttgtttc attcttatca taaaaagaag ttctcgaaaa
    20221 acgaactgtt ttccgagaac ttttttctat ccatctaagt gctcaaatca tattcacgac
    20281 ggaattctaa ggttaccctt tcttaaacaa actttatgtt atctgcacaa ctttttgcaa
    20341 ttttttcatt gcttcttacg aaatcgttga actctcttta gcataataca aagtgtagat
    20401 gaagtctggt gctttactcg ttttggtaaa aatgactgga aatcgtttct ggttattttt
    20461 ggcaaaggcg aggtgcaggt tcgattcctg ccttctacgc taacgatgtg gctgaaggga
    20521 acctccgatc ttgaatcgaa acgatccgca gtctattgtt tcaccaatga aacaaaatca
    20581 acgttcgtcc aagcatttcc tgaagccttg ctataaaccc caatttcaca aacacctgtt
    20641 gtaattggaa tgtctttgat tgtaattttt gtccattcac ttgttttaac aaccgcagta
    20701 tttagttccg ctccaccata atttttgata tataactgat tagtatcaaa ctctccccca
    20761 gacattacat aggcactcaa tgtgtaagtt cctttgctta tgccactaac attttgataa
    20821 gctgatgcct cgtatgcttg atcctgccaa aaagttagtt tgtagtcccc aaaaaaagtg
    20881 cccgcttccg ttttgatcgt acccttagcg gttccttgtt gaaaccaggt ttgccaattg
    20941 gaaggactgg tcgttggtcc atcgctttcg aaacttgcat ttttaactag atttatttgc
    21001 gcccctgctt gtttaaacgc acgcaagctt ggcaaggcgt ttccagcaaa atcaaacatc
    21061 gcttggttgt cccattcgtt tcccatagtg gattgaacac tgagataatt catacctgct
    21121 tgtgttgccc aactcacatt tccgttgtac caaagaggtt cccaatagaa gaagcccgcc
    21181 ccgcgattat tcggtactgc ctgaatccga tcggcaagat ccagcaaata ctctgcttgt
    21241 cctgtcggtg ttggttcata tccccccgca gctgcttcgg cttcaccaaa agcatttggc
    21301 atagtatcgg cattcgctgt tgtatgccca taagctgttt caactacgat cacttcttta
    21361 ccataccgtt ggctgatcgc attcatattg gtttgaagtt cattcattga accgtgccaa
    21421 tacggataat acgacactcc aattaaatca aatgacacac ctcgactcgt gatttcatca
    21481 aaccaccaag taaatgctcc tgtatcgcca ccatcagcta agtggagcat tactggagtt
    21541 gttttaggtt gagtgtctcg aacagcttgg ataccagact tcaaaaaagc agccaatcga
    21601 tcaaattctc ccccgccttc tccccaagac ttgccataag gccagagcat tccgctattc
    21661 agttcattgc cgatctgaac catatcagga taaacgtcca gctgcttcat ttccgacaga
    21721 acgttctttg tatagtcgta caatgccgta ttcatttctt caaaggtcag accttgccat
    21781 gctttaggaa gattctgttt cccaggatca acccaaaaat cactgtagtg aaaatccagc
    21841 agcaccttaa gtcccagatt ttttgctcgt tttgcaaggt caatcgtcgt ttccagatca
    21901 tttgtccctg ctccataact ttctccatta ctattataag gatcctgcca caaacgcagt
    21961 cgaacatagt tgacaccatt attttttaaa atctctaagg catcttttga aatatcgtct
    22021 tcataatatt ttgcaccaga tttttccata tctgacagga tcgaaatatc tgctccgcga
    22081 ataaattcgc tggcagatgc ttcaacagtt tttgaaacag cccccaaagc ccctaacaca
    22141 gctgcaaata aaacagcttt acgcaaccaa attcccattt tcattatggc tcctccttta
    22201 ttgaaattgg ttcagaataa actgaacagc tttttcagga tctctcgtta atccgatata
    22261 ttctgctcct tttgtcgcaa ccagcttgat tcctaagcga tcggtgtctt ctttgatatc
    22321 atcatagtaa gaattgactt gcggtgctaa gaccaccata tcaaaatcct gcagcatttc
    22381 gtaatgagaa ccataagcac ccgccattgc actgatcggt gctttcgatt cagatgcacc
    22441 tttttttaaa gcattagcta acatcgcact tgtccctgcg ccagcacaaa gtaccaacac
    22501 attgatttct ttatttgcat cgctgataac ttgactcgct gccacaggta cttcctcacg
    22561 tacatcggca gaagcacctt cctcggttgc gatcacctct gctttttgtg cttctttctc
    22621 tactaagaca gcatcgtatg ctttgcaaaa tggtagatag atcaggaagt caacgacgat
    22681 tagaaccgct gctagaacaa aagctaagat acccatgccc gttcctagaa ccaaaccgat
    22741 cggtgctgga gttgcccaag gcaaaacgta cataaagctg ttcatgccca atacatcgac
    22801 aaaaaacttg aacaggcaaa cgtttacaac aggtgttaac aaaaatggaa taaaaaaata
    22861 agggttcaaa atcatgggtg ccgcaaatag caatggttcg ttgacagcga aacttactgg
    22921 aataaaggaa gctttcccaa ctgccttcaa ctgcttagac ttagcaaaga gtaggaagat
    22981 aaaaggaaca accaatgttg ccccagttcc tcccatagtt cctacaaaat tccctaaacc
    23041 caccgtcagt actttagaag cttgttcacc ggaattgaac aattgcagat tggtttccac
    23101 attggcatag ataattgccg caattgccgg ctccacgatc gacggtccat gaacaccgac
    23161 aaaccaaaac agcgccatcg ctccccagat aatagcgatt cctaagtacc cgtcagctgc
    23221 tgtaaatagc ggctgcagca ccgtaatgat tgcttctgca aatgagattt ggaagatttg
    23281 tcgaatgcct aaatcaatta aaacggccgc aaatactgaa aaagagaaag gaaaaatatc
    23341 tcggaaggtt tgcgaaatcg ttccaggaac ttctttaggc attttaatgg taatatcttt
    23401 cagcacacaa aacttatata aattaactgt taaaaatgca gcgacaaagg aagccagtag
    23461 tccctttgtc cccatatatt ccgttgaaaa tccaccttca atcggagaga cgcttaacaa
    23521 caggaaactt accacagagg ccagcatcac agaggtggtg ttgattactt tgtttttcgg
    23581 taagcgacga ttcatcgaat cagccaagca gcgagcagtg gttgctgaaa cgagtaaccc
    23641 tacaacaccc atcgaataat tatagacttt ccatagccat gtggagacag attcaggcca
    23701 ttggtaacca aaaatctcag gaaccgcagc aatcaaaatg aaaatgcttg aaaataaaat
    23761 agctggcatc gctgttaaaa atccgtcacg aacggctcct aaataactat tacgtgagat
    23821 tttttcaaaa aatggtttcc ctttttcgat ttgtttaatg attccatcca tagcgttctt
    23881 ctcctatcct tgattctgtc tgtacagtac aataaagtct tgaatcagat ctctcagcaa
    23941 taaagtggtc attaaatgat cctgcccatg gataaaaatg aatcccatct ccatctcttt
    24001 cccagatgct tcttccgcta aaatttttgt ttgcgaatta tgtgcaaggg ttaaattttc
    24061 gtcggcttct ttcaacgccg aatcaacatg ttcaaagttt ccttgtctta cttctttcaa
    24121 taatttcaat aatgtactgc gagcgtcgcc tgaatatgca acgatctcaa aaccaagcat
    24181 ttgtaattcc tctttattca tcttttcttc ctccattatc acttattaaa taatcgtttt
    24241 ggtttcactg accaacttgt accagtaagc tgattctttt gggtaacgct tctgggtttc
    24301 aaaatcaaca taaaacaagc catacctttt gttataccca tttgtccatg agaaaagatc
    24361 cataagcgac cacaaaaaat accccttcac atttaccccg gctgttatcg ccttgcttaa
    24421 ggattccaaa tagactctca aatagtcgat tctcggctga tccataataa tgccatcttc
    24481 aaactgatct ttatacccca tcccgttctc agtgatatag attttgttgt aatgtgggta
    24541 atcgctttta attcgcagca acaagtcata tagaccttct ggataaatca gccagtccca
    24601 atcagttcga ggaattcctt ctttataaat acgttctccg attcccttca ctttataaac
    24661 agaggtccct ttttcacccg taccgttatg atggattgca ttttctccat cgtaagcttt
    24721 gacaaaatgg cattggtagt gattgatccc taagtagtca ttacgcgtgg atgctttttt
    24781 caattcaacg aaatcttctt caggaaaatg atagctggcc tgatttgctt cacatatctc
    24841 atcaagagca gtcaaggttt cagttgaata atagcctaaa taggtagcat ctaataagaa
    24901 acggatcgac aatgcatcgt ctaaaaaggc agcatgctta tcttccggcg cgtctgttgc
    24961 cgcatatttc gtctctaatg agtgaactac accaatttca cccggaagtt cgttttcttt
    25021 gaaatagttc actacacggg catgagcaac catcatatta tgaagacagg cgacgatctt
    25081 tgtaaaatca tatttgattc ctggtgggaa aacacctaac aaatattgat tggttgcaac
    25141 tggatagatt tcattaaagg tactccacac cttgacttct ttgaattcat gaaaacaaaa
    25201 aatggcatag gaaacaaatg cttctattgt ttctcgattc aaaaaatctc catggtcaaa
    25261 caaacgttta ggggtatcaa aatgatgcaa cgtcacaaac ggcgttacgt ttcttttctt
    25321 acattcttcg aacacacgat gataaaaagc gattccttct ggatttggtt tcccagctcc
    25381 atcaggaaaa atgcggctcc aagcaatgga taatcttaga ccatttacac caaaacgttc
    25441 acacaattca atgtcctttg catattgatg ataaaaatca cttgccggat cgggactgaa
    25501 tcgcccttgt tcctctaaaa agtcatccca agcaacagcg cctttgccac cttccttagt
    25561 ggctccttca acctgatagg ctgctgtggc tccgccaaaa ataaaatctt ctggtaattt
    25621 aagcatgtac atctctcctc aaatctataa tcagttttcg ctctttctaa ctgattgcat
    25681 tgtaaacgca tccaaaacat ttgtcaacaa aaacaaacac aaataatcat aaaaaccaga
    25741 aaacagcaat aaaatctatt gtaacaaaca taaaaaccac cctaaatgtt tacttttgtt
    25801 cgaattagat tgactgttgt ccgtttatat gatagattat ccttaaatta gaggtgaaga
    25861 caatgttgaa aaaagaaaga ttgcttacta tcgtagaaat ggtcaataaa aaaggaatcc
    25921 ttaccgttaa tgaaatcatc aatcaattag atgtttctga tatgaccgtt cgcagagatt
    25981 tagatgaatt agaaaaatcg ggcaagctgc tgcgtgtcca tggaggggct caaagtcttt
    26041 cctacacttt agatcaagaa ctttctcaca ctgaaaaagc cactctgcag attcaagaaa
    26101 aaaaagaaat tgctgccaca gcagcctcct tgattcacga gggagaaacg attttcttag
    26161 gaccaggtac aacaatcgaa ctattggcga cgcatttact gaacaagaaa attcggatca
    26221 ttacaaataa ttatccagtt tttgatattc ttgctcaagc agatggacca gaaattctac
    26281 tgattggcgg tgatttccgg aaaaataccg gcgcatttgt cggaccgatc accaacgaca
    26341 atttaagaag actaaagttt acaaaagcat ttatcagttc aaatggcgtt cacaacgaag
    26401 cgatctctac ttacagtacc gaagaaggag aagcacagca gatcgctcta aataattccc
    26461 gtaagaaata tctactcgtt gataataaaa aattcaatcg agatgatttt tatgtgtttt
    26521 ataatttgca tgatttcgat ctgctcatta cggatcgcca gatctcgcgg gaggttcaag
    26581 agcactatgc acaatatgtc gatctgcaaa ttgctgattc aaccgaaaat accactatag
    26641 gagcgtaact atgaaaggga ttatatttga tttcaacgga acaatgtttt tggactctca
    26701 tctgcatgaa gctgcttggc tgcatatgat acatgatcat acaaaagatg gtttatcaga
    26761 cgaggatatt ttaaaaaata ttcatggtcg gacgaatacg gagattttga aacatttcat
    26821 ttcagagcat ttgaccgcct ctgagatcgc cgtattgtca gaagaaaaag aaagctatta
    26881 tcgtatgctt tgcttgcaaa atgaaaacga gcttcagttg acaaaagggc ttgaagcgac
    26941 tcttgaccag ctgactgacc aacagattcc attaacgatt gccacggcta ctgtcaaaga
    27001 gaatgttgct ttttattttg atattttcga tttagcccgc tggtttgact gggacaagat
    27061 tgtctatgac gacggctctt tccctgggaa accgcaaccg gatatttttc ttaaagcggc
    27121 agacaaactg agcttagctc cggctgattg tcttgttatc gaagatgctt actcaggatt
    27181 acttgctgcc aaacgtgcgg ggatcggaac aattattgca attgatccat tcggtaaaaa
    27241 caaaacagta tttgaacagg cacagctaaa taaagatgga accatcaaag attttactgg
    27301 tttttggaca gagcacctgt ctgccacatc cgttaattct taaacgattc aactaactac
    27361 caaagaaaag caactgaaat gcacacctcc ttttataaaa aactgccagt gaaacgacat
    27421 gaaagataca ctgctatatc cttagtgaaa tatagcagtg tatctttgac tttttcattc
    27481 ttttaaccat atgacgcgtt catctctatc tataattaac attaaaaata gtgttttcac
    27541 attatttctc aaaccaatct taaaaatcat caggagtact tttttgatat acttttatta
    27601 atgctgggcg taatggttaa aagatttcca ctagttcctc tccaccaagc tgagttgaaa
    27661 aatgcttatc tgtaaacaac atagacaaag aggaaataaa cgtttccgta tctttctctg
    27721 tcccaaggat attaattaat tttcctacta ggtaagtatc attaaactta agatctgcct
    27781 tcacatcaaa agttttgata aaagctttta tcatgcgtac aattttgtct ttatcgccat
    27841 aattgatttc accactcata tcaatatagt cactaatccc tgaagaaa
//
LOCUS       DAPBCF010000035        26895 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.035, whole genome shotgun sequence.
ACCESSION   DAPBCF010000035 DAPBCF010000000
VERSION     DAPBCF010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.035"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(40..1146)
                     /locus_tag="RD508_001845"
     CDS             complement(40..1146)
                     /locus_tag="RD508_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDT7736404.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRTRYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            1356..2357
                     /gene="ccpA"
                     /locus_tag="RD508_001846"
     CDS             1356..2357
                     /gene="ccpA"
                     /locus_tag="RD508_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HDT7736405.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLADRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEGFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(2694..5039)
                     /locus_tag="RD508_001847"
     CDS             complement(2694..5039)
                     /locus_tag="RD508_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDT7736406.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            5318..6220
                     /locus_tag="RD508_001848"
     CDS             5318..6220
                     /locus_tag="RD508_001848"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDT7736407.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            6433..8208
                     /locus_tag="RD508_001849"
     CDS             6433..8208
                     /locus_tag="RD508_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HDT7736408.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(8274..9860)
                     /locus_tag="RD508_001850"
     CDS             complement(8274..9860)
                     /locus_tag="RD508_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HDT7736409.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQEMVEEIE"
     gene            10111..10335
                     /locus_tag="RD508_001851"
     CDS             10111..10335
                     /locus_tag="RD508_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HDT7736410.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            10476..12227
                     /locus_tag="RD508_001852"
     CDS             10476..12227
                     /locus_tag="RD508_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7736411.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSVKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIISAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            12227..14011
                     /locus_tag="RD508_001853"
     CDS             12227..14011
                     /locus_tag="RD508_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7736412.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            14337..15188
                     /locus_tag="RD508_001854"
     CDS             14337..15188
                     /locus_tag="RD508_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7736413.1"
                     /translation="MLIEKVLNNNVVITRDERDREMIVMGKGLAFKKKVGDPILDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVHLNDSVYISLTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVVQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            15285..17165
                     /locus_tag="RD508_001855"
     CDS             15285..17165
                     /locus_tag="RD508_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7736414.1"
                     /translation="MGKYQELAENIVKNIGGKENIRSLTHCVTRLRFKLKEENKAKDD
                     VLKKMEGIVTIMKSGGQYQVVIGNHVPDVYAEVLTVAGISDEVEEEVSSSSNLFNRLI
                     DILSGCFQPFLGALAAAGMVKGLNALFLFLKFYTEGSGTYIMLNGIGDAIFYFMPVIL
                     GYTAAKKFHLNPMVGLVIGAALCYPTVQGAALQSGFPDGSPAPYSLLGLPAYETFLGI
                     PWVGSSYTSSVVPVIFIIAFAGQVQKIAKKWIPAVVQTFLVPFSVLLIALPAGFLIIG
                     PIVSILTDLLSTGFQALMDFSPAVYGAVLGFLWQVLVIFGLHWSIIPLAIMQLAQNGW
                     SQMLVGVYGASFAQTAVVLAMYFKFKDQKMKALCMPAVISGIFGVTEPAIYGITLPKK
                     KPFIYSMIGGAISGIYLMASGTISYTMGGLGIFGVVNYITETDASGMFQAFIGIAIAS
                     VIGFSLTFFFWKDEAGETDAIQKKSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGRGI
                     LIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESLVQ
                     QGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALITA
                     LT"
     gene            complement(17205..18107)
                     /locus_tag="RD508_001856"
     CDS             complement(17205..18107)
                     /locus_tag="RD508_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7736415.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENKVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            18338..19741
                     /locus_tag="RD508_001857"
     CDS             18338..19741
                     /locus_tag="RD508_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDT7736416.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALNDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            19741..21174
                     /locus_tag="RD508_001858"
     CDS             19741..21174
                     /locus_tag="RD508_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDT7736417.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQVKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            21319..22245
                     /gene="trxB"
                     /locus_tag="RD508_001859"
     CDS             21319..22245
                     /gene="trxB"
                     /locus_tag="RD508_001859"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDT7736418.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            22459..24186
                     /locus_tag="RD508_001860"
     CDS             22459..24186
                     /locus_tag="RD508_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDT7736419.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEEAKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            24201..24551
                     /locus_tag="RD508_001861"
     CDS             24201..24551
                     /locus_tag="RD508_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDT7736420.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(24643..25503)
                     /locus_tag="RD508_001862"
     CDS             complement(24643..25503)
                     /locus_tag="RD508_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HDT7736421.1"
                     /translation="MSSDSTEVVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLKQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            25595..26023
                     /locus_tag="RD508_001863"
     CDS             25595..26023
                     /locus_tag="RD508_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDT7736422.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            26185..26361
                     /locus_tag="RD508_001864"
     CDS             26185..26361
                     /locus_tag="RD508_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDT7736423.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            26388..26834
                     /locus_tag="RD508_001865"
     CDS             26388..26834
                     /locus_tag="RD508_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HDT7736424.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         8510 a         4797 c         5747 g         7841 t
ORIGIN      
        1 aaaaaggtgg gagcggacta gctctcacct tttttactct tatttttcta aaacaagtaa
       61 ttcttttggt gtagtcgtga atggcacaca gccatcgctt gtcacatata cacagtcttc
      121 gatacgtacc cctacttttt caggaatata gattcctggt tcaagagaga agcacatccc
      181 ttcttcgatt actaagtcat ttccttctac aagggaaggg aattcgtgga cggttgttcc
      241 gatcccgtga cctaaacggt gattgaaata ttcgccgtag ccatagctgt tgatcacgtt
      301 tcgtgcgatt tgatcaagtt cacctgctgt cacacctgga cggacggctt cttgtgcggc
      361 aagctgtgct tcaagagtga tgttgtagat tttttcttgg aagtcggttg gtttttgata
      421 agcaattgta cgagtagcat cactgcaata gccattccaa acaacgccaa gatcgaataa
      481 cacaagttca ttcggtgaaa tcttcgtatt tcctggtgta ccatgagggc ttgcagcatt
      541 tgctcctgca aggactaatg tgtcgaaaga catttgtgaa acaccttgtt ttttcaattg
      601 gtattcaatt tctgcaatga tcgcttgttc agtcacgcct tctttcactg ctttaaagcc
      661 aatctcaaat gcaacatcgg cccatttacc agcttcgatc agtttgtctt tttcctctag
      721 agttttgatc agttgtagac gttggatgat ggaagttaga tcagtgtaag aatccgttcc
      781 cgtcaagata tcagagatag catcgaagcg ctcgacagtc aaggcgttct tttcaatccc
      841 tacattgcca ggctgaccat agcgagtacg aagttctttt ccgatgatct cccaagggtt
      901 ttcgctgtct aaatagccgc ggacatcata cgcccaacta ctgttttgag catcttcaac
      961 ttccaaagca ggagtgaaaa ggaaaggatc ttgttcaaga gggataaaaa gagctagtac
     1021 acgctcatga ggatcacttt cgtatccgga aaagtaagcg atgtggccag ggtcgctgat
     1081 ataagccaat tcgacttggt gttgtgccat ccattgacgt agttcattga tttttacgtt
     1141 attcatttgg caacctactt tctaaattaa ttttgtattc aataattgta ccactgattt
     1201 attaaaagac caacgttcta aaaactgaaa aaagtaaaaa ttttcatgaa aacagagata
     1261 aaacggttgc aattcttgag attatttgat attctatttt agaaatgtaa gacgtatttt
     1321 cagaaaacat ataaaatatg aatgggagaa cacaaatgga aaagcaaaca atcactatct
     1381 atgatgtagc gagagaggca aatgtttcga tggctactgt ttcacgtgtc gtaaatggca
     1441 atccaaacgt taaaccagca acaagaaaaa aagtcttgga agtcatcgat cgcttggatt
     1501 atcgtccaaa cgcagttgcg cgtggcttgg caagtaagaa aacaacaaca gttggggtaa
     1561 tcatccctga tgtcagcaat atgttctttg cttctttagc acgtggtatc gatgatgtgg
     1621 caacaatgta caaatacaat attatcttag caaattcaga tggcaacgac caaaaagaag
     1681 tcaatgtatt gaataactta ctggctaagc aagtggacgg cgtgatcttc atgggtcacc
     1741 atatcacaga cgaaatccgt ggagaatttt cacgttcaaa aactcctgtt gtattagctg
     1801 gctctattga tccagatgaa caagtaggta gcgtaaacat tgattatgta tccgcaacaa
     1861 aagatgcagt aaataaattg gcaaaaagcg gcaataaaaa aatcgctttt gtcagtggtg
     1921 cgttgatcga tcctatcaat ggacaaaatc gtctgaaagg ctataaagaa gcattaagcg
     1981 aaaataacct accatatagc gaaggattga tctttgaagc acaatacaac ttcaaagatg
     2041 gtctatctct agccgatcgg atccataata gcggtgcaac agctgtctat gtttcagatg
     2101 atgaattagc catcggtatt ttggatggtt tattagatcg tggcgtgaaa gtaccggaag
     2161 gattcgaaat catcacaagt aacaattcac tactgacaga agtagctcgt cctcgtttaa
     2221 caagtatcac acaaccatta tacgatttag gggcggtatc tatgcgccta ttgacgaaaa
     2281 tgatgaataa agaagaagtc gaagaaaaaa cgattatctt gccttatgga atcgaagaaa
     2341 aaggatctac aaaataataa aaggacaacc attcagaggt tgtgagcctg ccgtttaact
     2401 ctgcgttaca aggagcaatt tcaaaaaaca gcatttcatg tttgatgaat attgtgactc
     2461 gtgattcgga gttggcagga gaacaccgtt tattcgggaa aaggggttat gacaaaattt
     2521 tgttataatc ctttttttgt gtcttaaaaa agagagaaag tggttgaaat tacatttatc
     2581 gtatataaaa caatccgtgt atagatgctg cattttgttc accaccatca aaaaaataag
     2641 ggactgtgac aatactattg tcacaatctc ttattactgt gtattctatt aaatcaatca
     2701 tctttctcat ctgattcttt ggttgcttga ttcgctcttg cataagctga agcggtgttc
     2761 cagtaatctg tatagttttc atcggtaccg ccaacgccaa atttaaaggc gcttttcttc
     2821 ggtccatttt tcgcccatag cgattcaact gtttttccag gtgtttggat ggatttttta
     2881 ttgacagtaa cttttccagg tgtttgacca gtaaatccag atactttttt cttcatcaca
     2941 tcagatgata attcgaattt ctcatcagtg ccaaaaatgt caggttttgc ttggtaagct
     3001 tgattgatca gattggcaag ataattagcc gaacgtatcc ttgctttgct gtccattcca
     3061 gtattgtcat cgtgccctgc ccagctactg atggtaatag acggagtaga gacaattagc
     3121 catgaatctc ggtattcatt ggtagaacca gtttttccga cccaatctgc ttttcctaga
     3181 tttccgttta agcttgagat ggcatctttg aatggtgtag tgatttttgc attgatcaca
     3241 ctgcgcatca tgtcattcat gatcgatgcc gttgcttccg aatagatccg gacagagttg
     3301 ctttcgtgtt tataaattac atttcctgcg ttatctgtga tggaatcgat gatatagcct
     3361 tcttcataga cgccgccgtt tgctaaagcc tgaaatccat tggtctgttg aagcgtcgtg
     3421 acatctactg tacctaaagg agcagattca acgccccaat tgtcatttgc cgggtagttc
     3481 atctttgcca agtagtgctc gtaagcatat tgtttcgatc caccggaatt caacacatct
     3541 tgatataagt gataagccgg gatattgttg gaccattcta gtgactcacg gacggtttgg
     3601 aaggtgttcg atccttcgtt agtagcattg acgattttct cgccagcatt ttctccttct
     3661 tgccaagttg ttgcataatc tgatacacgg gattctgatc cgataagccc catgtcgatt
     3721 gcaggtccat aaacaagaac tggtttgatt gatgagccag cttgacgttc tgtatcgaag
     3781 gcatggttat tttgattctg actgtaattc cgtccgccaa cgaatccgta gatgcggcca
     3841 gttctgttat ccatcaatac atttccggtt tctacttgac tgccagcacc atcatctaac
     3901 atgtatccat aattttctac gccattttgc aatgcagcat agacatcttt atcgattgtc
     3961 gaatggattg tatatccttt attttggatt gtttgctgtg ccttttgata ataagcgtca
     4021 ctgaccgatg aatcagacat atcagcgttg tctttttcag ccaattgttg tgcaatgatt
     4081 cttgttgctt cattcatcac agtataatac aagaattctc tgtcagtctg ttctgcgatt
     4141 tgttgtggta gaaagtcttt tgtaaggtca taggcttttg cttcttcgta ttgttctttc
     4201 gtaatttggc cttcacgata catactgaat aaaacaaaat cttttctggc aaggccggca
     4261 gaaagatctt cttttagcgc acctgtgttc gtgtatggac tatacgtgat cgggctttgg
     4321 ggtaatccag cgatataagc agcttgcggc agcgtcacat cttttgcatc tacaccaaag
     4381 attcctcttg cagcttcctg gactccagca atgttttgtc ccttattatt acgaccaaat
     4441 ggtgagacat tcaaatacgt agcaatgatc tcatcttttg aaaagtattt ttctacttgt
     4501 gcagaaagaa tgatctcgtt tgctttacgt ttgaatgttg tttcatctgt aaggatctgc
     4561 tgtttgacta attgctgtgt caaagttgat ccaccagaag agccaatacc agtagcttca
     4621 gatactaacg ctcgtaaaac agctttagga acgtaacctt ggtgtttatc gaagtattca
     4681 tcctctgtgc tgataattgc agttttcaat aaaggtgaaa ttttatcaga tgaaatagtc
     4741 gtgcgcatca gatctgtctg gatttttgat atctctgtat tatctgcata aacaatcttt
     4801 gacgtttctg taatgtttcc tagttctgtc tgcagtgctt ttttagtcgg caattgtgtg
     4861 tcttcgacga gataggcaaa atagccagcg cctattccaa tacctagagc tgcgaacatc
     4921 aaaagaagaa cagtaataaa aacagtcaat gattgaaaaa ctctaaaaat aatcttagga
     4981 acaaaccatt tttctttttt tcttctattc tgtttttttc gagtattttt gcgtggcaaa
     5041 agggtcacct caactaatgg ttttatttcg ctaattatag caaataatag aacaaaaaaa
     5101 cagacaaggc tgtttttggc aggaatttct tttttaaagg agttaaaacg tgagaaaatg
     5161 atctttttta taaaagagtt cttaagcttt tctttagaga aaatttcagt tactatggag
     5221 aacagggcaa agaaaaatca atcattttct ttgtatatca tcttaccaat atataggaat
     5281 tgttagtaac aattgccttt caaggaggaa tccatccatg ttattaggct cacacgtcag
     5341 catgagcgga aagaaaatgc tgttaggagc agcagaagaa gcagccagtt atggatcttc
     5401 gacttttatg atctatacag gcgcccctca aaacactaga agaaaagcca tcgaagagat
     5461 gaatattgat gccggaaaag cgtacatggc agaaaacggt ctaacaaata tcgtcgttca
     5521 tgccccttat atcattaatt tggggaatac gatcaaacca gaaatgtttc cttttgccgt
     5581 ccaatttctg agagaagaga ttgttcgtgc ggaagcttta ggcgctactc aaattacact
     5641 tcacccaggt gctcatgtag gggcaggaac agaagccgga attgctagaa ttattgaagg
     5701 cttgaatgaa gttttgacaa aagaacagac ggcacaaatc gctttggaga caatggcagg
     5761 taaaggtacg gaaatcggtc gaacatttga ggaattagcg caaatcatcg atggagtaaa
     5821 attgaatgaa aaattatccg ttacttttga cacctgtcat acgaatgatg ccggttataa
     5881 tattaaagaa gacttttcag gtgtaatgga agagtttgat aagatcatcg ggttagatcg
     5941 gcttaaagta ctccatatca atgattctaa aaatccgcaa ggttcgcata aagaccgaca
     6001 cgccaatatt ggttttggaa caatcggatt cgacacgctg aataagatcg tccatgatcc
     6061 aatgtttgac aatatttcga aaatcttgga aactccctat gtcggcaaag ataaaaagaa
     6121 agcttacgca ccatatggaa aagaaatcgc catgttcaaa gcacaaatat tcgatccaga
     6181 agtgtttcct gagttattag cagaagaagt gatactctaa gattttctat ctgacagcag
     6241 caaaaaagga ccaggcacat tgccttgtcc ttttttgttt aagaaacaaa ggagtgcttt
     6301 ttgcagtctt tttcatcatg catcttctcc cccctctttt taaatttaga caaacagggt
     6361 atactggtag aaaagtaaaa aaacgaaaag tttcacaagc aagtggcaaa acgtgattgg
     6421 aaggacgaaa agatgctgaa cactttaaaa cccttgatca accaactaaa aaagaaacat
     6481 acatacttta ttcttggcat agccctatta tttacaatta ttcgtttgta tttatatagt
     6541 aaagcaatct atggaacaga catgtcggca acctatgatg accagctgct gattcgctat
     6601 gctcaaaata ttttggacgg taaatggcta ggggagtata cgactacaac actttccaaa
     6661 ggaatctcct acagcttatt tttagtactt gcacataaac tgcatctttc ttatgcagtt
     6721 ttgttcggca tgttcagtat ttttgccagt atattggttg cactcgcgtt taaaccgatc
     6781 gtgaagaaca agtatcttct tttaagtttc tatttttatt ttttgttttc tccgattagt
     6841 tttacacatg aatattccac tcgaacgtat cgtaatgccc tcgtgattcc ggctgttgag
     6901 atcattatcg cttgtttact agctatttat taccgcaaat acggttctag cagaaaattg
     6961 ctgccatggt ttttagggct ttctgtcgct tttcctttct tttggttcat tcgcgaagat
     7021 tctatctggc ttcttccttt tactgtagta gctttgggta tcagtttcgt ccagatcttg
     7081 ctagggcaag acttttcttt caaagaagta aagaagttaa aaaaacgact ctttcttctc
     7141 tcgaaacggg aatggctgaa actttcattg tttttacttc ctatagttgg cttttccatc
     7201 gtctatcagt ggatcgaata taaaaatgag acaacatacg gtattgcaac catcaatgac
     7261 cgttccagtg gagaatttgg acgtttgatg aaacaactga tccgaataga tgatgaaacg
     7321 aacttgaata aagaaaacag tgagatatgg gtctcacatg ctgcactaaa taaagcatta
     7381 gccgcatctc ctacattcca tactgtttct acccgtattg acgaattata tacgactcac
     7441 gcgtggactc aaggtggaaa agtaaaagaa ttacccggag atatcatctt ttgggcattg
     7501 cgagatgtgg taagcgaatc tggttattac caaaacaatg caaaagaaac caatgatttt
     7561 tggaaaaaag tcaaccaaga attagaagaa gcctatcaca agggaaccat caaaaagaaa
     7621 aaagagttct atctgatggg atcaggagat ggaaagacga tgagtgatct accaatcgta
     7681 ttcgatttcc ttcaatcagg atacgcttat gcatggcgat ataaagattt ccatcaagga
     7741 ggaaattata gtttcggaac gcaagaacaa gtcaaacagg ctcaagaatt attaaacctt
     7801 ccgctaatgg agaattggat cgatagtaat gaaccgagaa cacctaattt ccaattaaca
     7861 aaatcagcaa aagtcgcgaa tgtcatcata aaaatttacc aagttctggc tattcccgtg
     7921 ctgattgctt caatagcagg gatattactt atgatactag gaaccgtatt tgcaaaagct
     7981 gatcgtgcct attatagttc ctctttgatt gtggtcaccg gattaatact gacacaattg
     8041 gtttttcttt tcggtgtctc gtggttttgt tcttatgcgc cagaaaaaaa ggattatttt
     8101 ttaagtgtct acactggcgc aggcgtgccg ttaacgcaat tcatcgtagt aacaagcatg
     8161 ctagttttca gtaaattaaa tctgaaaaaa gctttatctt ctaaataaaa agacccttgg
     8221 tagctagatt tttaacctaa ctatcaaggg tctttgtgtg gaaaaatcag tttttattcg
     8281 atttcttcta ccatttcctg caaacgctgt tcatattttt tgtttccttt atataaatca
     8341 ccaatcgtcc atgccaacag gaggaggaca agaacaatga ttacataagc gatgtgatca
     8401 gccaatgcta gttgagcgga agtggcttgc tcgccgaaga aactttcgat ctgtcctggt
     8461 aatcctcgta agttcaagta agttagacta atcacagaga accagccaag aagttttacg
     8521 atgaatgaat ttttaaatcg gctacccatc tccgcttggc tgttggtcat catcagtaaa
     8581 gggatcatcg aaaacggcaa cgcaaaagcc aagaacacct gggattcatt cattaagtta
     8641 ttcaaagcgg tatgttcttc gatcgttcct tttgtacttg taaacaaaac acaaatcaat
     8701 acaggaatca cagaaagcaa tcgtgtgacc agtcttctta gccaaatcgg gatacgcata
     8761 tggatgaatc cttccatgat gacttgaccg gtcaacgtac cagtaatagt agagttctgg
     8821 ccagaagcaa gaagtgctac agcaaataaa gtggacaaga taccagattt tgctacagca
     8881 atcaagatac cattgctcat agctgatgga tcagataaag cttcatacag accaaaaaag
     8941 gaaggatctt gaacagaacc ggttttgaag acagcgacac ccataatcaa tagcagcgca
     9001 ttgactagaa aagccatcga caattggata ttagagtccc aagtagaaaa acgtacagct
     9061 tgtgctacat cttcttcgtc ttggtgatcg atcttccgag tttgtgaaac tgctgaatgt
     9121 agatataagt tatgtggcat gactgttgcg ccaataatcc ctaatgctcc agttagcgga
     9181 gtttcgccac caatgacagg tgagtcggag aatgtatggc tgttagggat aaagccagca
     9241 aataaactgt gccaatctgg gttagacaag ccaacttgat agacaaaaac gaataaaatg
     9301 acgaaaatca agcagacaac cagtgcttcg atcttacgaa acccgacttt tgtcagtagt
     9361 aagagaacga aaacatctaa tacagtaata aagacggcaa tcaccaatgg aatatcaaaa
     9421 agtaagtaga gggcgattgc tgcaccaatg acttctgcaa tatctgttgc cataatggct
     9481 aattcagtca agatccataa aatgacaccc aatgtcttac ttgtgcgtgc tcggattgct
     9541 tgggccaaat ccatttgggt cacgattcct aattttgctg ccatatactg taaaagcata
     9601 gcaatcagac tagacatcaa aataactgac atcaataaat attggaaatt ttgtcctccg
     9661 gtgatcgaag tagaccagtt acccgggtcc atatacccaa ctgctactaa cgcaccaggt
     9721 ccagagtaag caagaagtgt tttaaaaaaa cttttcccct ttggtacatc cactgttcca
     9781 tttacttcag ctaaagataa accatttgta tgttcaataa gtcgatgctt atgaaattgt
     9841 ttgttggatt gattattcaa gaaaaaacca cctttcctat ttatctacga ttacattcta
     9901 cacctcaaaa agaaaaaatt aaagaaaaag attcggtatg cctaattttt tttcgtggcg
     9961 tgtcttgcta gatgacgaaa gaaattttgt tctcctctaa aaaaaccact attttttgca
    10021 tgaaactaaa gaatacgcct ttcttttttc aataaacttt agtaaaataa gtcattgaga
    10081 gcaattcgga aatagaaagg agagatttat atgttatcaa caggtattgt cgtacttatt
    10141 gctattattg ctttgctaat cggcgcagta ggtggctttt tcctagcgcg taaatatatg
    10201 aaagactatt tagaaaaaaa tcctcccgtt aatgaggaca tgttgcgatc aatgatgatg
    10261 tcaatggggc aaaaaccatc tgagaagaaa attcgccaga tgatgcagca aatgaagaac
    10321 caagggaaaa aataggttct gacccaacga ctttttacgg gctgattttt tcagtccgtt
    10381 ttttatttcg taatttgtta gactattcag attattcagc aaaaagacaa gcacagacaa
    10441 tcctaggctc ttgataaaga caaaggagga gtaaaatgtc gatttttaga aagttaggct
    10501 ggttttttcg tcaggaaaag aaacattatt taattggggt tttctcgcta ttcgcagtgg
    10561 ccttggtaca gttagttcct ccaaaagtga ttgggatcat cattgatgag attgccgata
    10621 aaaatttatc agtaaagatc attttcgggt ggatcttcct attgattatc gctgcttttt
    10681 tacaatatct ttttcgttat atctggcgga cgaatatttg gggaagtgca gctcggttgg
    10741 agaaagaact tcggcagcag ttattcaaac attttacaga aatggacaat ctcttttacc
    10801 aaaaatatcg gactggggat ttgatggctc atgcaacgaa tgatttgaat gcgatccaga
    10861 atgtagcagg agctggtatc ttgacctttg cagattcagt gattacgggc ggaacaacga
    10921 tcattgcgat gattttgttt attgattggc gcttaacact gattgcgctg attcctctgc
    10981 ctttgctggc cgtcacttca cgagtgctgg ggtcgaaact ccatgatgct tttcgtgatt
    11041 cgcaagaagc tttttctagt atcaatgata agacacaaga aagtatcact gggatcaaag
    11101 tcattaaaac atttggacaa gaaaaagaag atctagcgga ttttgaagaa aagattgaag
    11161 atgcaattat taaaaacaaa cgagtcaatt ttttagactc cttatttgat ccattcatta
    11221 ccttgattat cggtctgtct tatgttgcaa caattatttt aggtggaaag tatgtcttgg
    11281 aaggcacgat ctcgatcggg cagatggtct catttattag ttatatcggt atgcttgttt
    11341 ggccgatgtt tgcgattggt cgattgttca acgtattgga aagaggaaat gcttcttatg
    11401 atcgcgtcaa tgaacttttg catgaaaaaa cgcatatcgt ggaacaactg ggtgcagtgc
    11461 agaccccggc aaaaggcgag ctgaatgtag ctatttcctc ttttaattat ccgaaagaag
    11521 aatcaccagc attagaacaa atcaagtttg caatccaaga aggagaaaca ttaggtattg
    11581 ttgggaaaac tggtgcggga aaaacgacga tcatcaaatt actgatgcgt gaatacgatg
    11641 attatcaagg gaaaatccaa tttggcggac gttcgatcaa agaatattca ttgaatgctt
    11701 tattaggatc aatcggctat gtgcctcagg atcacttctt gttttcgatg accattcgag
    11761 ataatatccg tttttctaat ccaaaacttt cagaagaaga agtagagcat gcggcttctt
    11821 tagcatttat caacaatgaa atcaaggaat taccaaaagg ttatgatacc ttagttggag
    11881 aacgtggagt ctctttatct ggcggacaga aacaaaggat ttcgattgct cgagcattga
    11941 tcaaaaatcc tgaattatta atattagatg atgcactttc tgcagtagat gccaaaacag
    12001 aagaagctat cttgcataat ttaaaagaaa taagaaaaga gaaaacaact atcatttcag
    12061 ctcaccgttt aagtagcgtg atgcatgcaa aagaaatcat tgttgtcgat caagggaaaa
    12121 tcattgaacg aggaacccat catgagctgc ttgcactagg cggctggtat gaacaaatgt
    12181 gggagaaaca gcaattagaa gcgaagatag aaggaggcga ggcctgatgg atgaaaatta
    12241 tcaatcggaa tggacaaaat cgattccact taaagaacag aaaaagatca tcaaacgact
    12301 gatgaagttc gccaaacctt ttagaagaac gttcatcgtt gctatcttat ttgcgtttgc
    12361 tctgtctgtg atcaatgtcc tattgccaag gatcatccaa acttttatgg atgatcatct
    12421 ggctaaacag tcggctacga cacaagttat tttgtttttt gctggtatgt acttatttgg
    12481 agtcatagta aaaagtatca tttggttttt ccaatggtat ttgtattcca tggcttcatt
    12541 gaagacctat cagtatatta gggtaaaatt atttgaaaag ctgcatacac taggtatgcg
    12601 ttattttgat cagacaccgg caggatcaac cgtttctcga gtgacgaatg acacagaaac
    12661 gctatttgaa ttttggtacg tctttttgat ggtattgact gggatctttg cagtcgtttc
    12721 ttcattcatt gccatgtttc aaatcaatgg agaaattgcc ttgtggactt tggtgttctt
    12781 gccaatttta ggaatagtca tctggtatta ccagaaattt agttctcgta tttaccggaa
    12841 tatgcgggaa aaattaagtc agctgaatac gaaattgaat gaatcgattt ccggcatgcg
    12901 tattatccag cagtttcgcc aagaagctcg tttagctaaa gaatttgaac aagtgaacaa
    12961 tgagtattta gacacgcgtt atgcgatgat caaaacaaat tcgattctgt taagtccgat
    13021 catcaatttt ctatatgcat tggcgattgc gttggtgttg actttgtttg ggatcgatgc
    13081 gttgcattct cccgtagaag ttggactgat ctatgcattt acgacctatg tccagggatt
    13141 ttttaatcca atgtctcaaa tgatggactt tttgagcatc ttcacagatg ggatggttgc
    13201 tggtagtcgt atcttgaaga ttatggatac agaagaatat gcaccacaac aaaaccctgg
    13261 agcagatcaa atgattactt caggtaagat tgagtttcgc aatgtaagct tttcttatga
    13321 tggagagcac aatgtattaa acaatatctc ttttgttgct aatccgggag agaccgttgc
    13381 attagtggga cacaccggaa gtgggaaaag ctcgatcatc aatgtgttga tgcggtttta
    13441 cgaattttat gaaggtcaga tattgattga tgatcatgac attcgagaat atccaatgga
    13501 agagttacgt aagaaaatgg ggctggtctt gcaagatgct ttcttgtttt atggggatat
    13561 cgcaggaaat attcggatga tgaatccagc tatcacagac gaacagatac gccatgcggc
    13621 tgagtttgtt caagcaaaca aattcatcga tgaattacca aaaggatatc actcaaaagt
    13681 gatcgaacat ggtgccagct attctagtgg acaacgacag ctgatcactt ttgcgcgaac
    13741 aatcgtgact gatcctaaaa ttctagtatt ggatgaagca acagcaaata tcgatactga
    13801 aacagaagga ttgatccaag aaggattggc gaaaatgcga caaggacgga caacgattgc
    13861 gattgcccat cggctgtcaa cgattcgaga tgcagaattg attttagttt tagacaaagg
    13921 tcatatagta gaacgcggga atcatgaaac acttctagcg caaaatggtt tgtatgcaga
    13981 tatgtacaaa ctgcaaagca gtggtatata aaagatgttg tgacagtagc attttgacct
    14041 aagcactaga gtgaaaataa aacatagctt cccatatttt tcatctgtga gagttagtgt
    14101 cgtagttacc agatttaaaa aagacgacgt cagctagtca gaagtgccta atagccccta
    14161 agaaagcgtt gacaaaatcg tttgctttcg ataatataaa gaaaacgata caacttggat
    14221 agtgattgcc tgatgcaagc taaacctaat gagtctccca tggtttcatg gacggctttt
    14281 tgggtttttc tttttgtttt ggatacagcc ctatatatca tggaaaggag caaaacatgc
    14341 tgattgagaa agtactgaat aacaacgtcg taataacaag ggatgaaaga gatcgggaaa
    14401 tgattgtgat gggaaaagga ttggcattca aaaagaaggt gggtgacccg attcttgatt
    14461 catgcatcga caaaaaattt cagttgacaa atgacggact ttcacaacag ttccaagaat
    14521 tggcacaagc gattcctctt gagtacttag aaatttcttg tgaaatcatt gaatatacaa
    14581 aagaggctct gcaagtccat ttaaatgatt ctgtgtatat ttcattgacg gatcacttgt
    14641 atacagctat cgaacgtcaa aaaatgggga tctttgtgcc aaatgtattg ctgtatgata
    14701 tcaaacaact gtttcctaaa gagtatgcca ttgggaaaaa aacagtgaag aaaatctcgg
    14761 ataaatacca catcaagtta tcagaagacg aagccggatt tatcgcattg catttagtca
    14821 atgcacaagg cattcaaagc cagcaagaca atacctacct gtttaccaca acaatacagg
    14881 atattttaaa tatcgtccgc tattactata agattacatt tgatgaagat tcagtccact
    14941 tttttcgatt cgtcacacac ctgcgttttt ttctgacacg tgttctagat ggagcgaaat
    15001 cagaagatgg agaagtttct gaggaattgt tccaagttgt tcaaaaaaaa tataaggata
    15061 cgtttggttg cgttgagaaa atagcagact ttttaaccgg ggctttcgac taccagatgt
    15121 ccacggatga aaaaatgtat ttaacgatcc atactgcgcg tttagtgcat gagaatcgtt
    15181 gtaaataaat aaaaaaggag gacaaattaa caagaacgta tgaaaataag ggtagtgaca
    15241 ttcagttggc taaaccttcc actaattaat tggagggaat agaaatggga aaataccagg
    15301 aattagcaga aaacatcgta aagaatatcg gaggaaaaga aaatatccgt agcttgacac
    15361 actgtgtgac gcgacttcgt ttcaaactaa aggaggaaaa taaagcaaag gatgatgttt
    15421 tgaaaaagat ggaagggata gtcaccatca tgaaaagcgg cgggcaatat caagttgtaa
    15481 tcgggaatca tgtgccagat gtctatgcag aagtactgac agtagccggg atttccgatg
    15541 aagtagaaga agaggtttct tcaagtagta atctgttcaa tcgattaatc gacatattaa
    15601 gtggctgttt ccagcctttt ttaggtgctt tagctgcagc gggaatggtc aaaggattaa
    15661 atgctttgtt cttgtttctc aaattttata ctgaaggatc gggtacgtac atcatgctga
    15721 atgggatagg ggatgcaatt ttttatttca tgccagtgat cttagggtac acagcagcga
    15781 aaaaatttca tctgaatccg atggtggggc tcgtgattgg tgcagcactt tgttatccga
    15841 ctgtacaagg agcagcacta caaagtggtt tccctgatgg cagtcctgcg ccttatagct
    15901 tgctgggtct tccggcttat gaaacatttt tgggtatccc atgggtgggc agcagttata
    15961 ccagtagcgt cgtacctgtt atcttcatta tcgcatttgc cggacaagtc caaaaaattg
    16021 ccaagaaatg gattcctgca gtcgtccaga cctttttggt tcctttttct gtgttattaa
    16081 tcgcacttcc tgctggcttt ttgattatcg gtccgattgt cagtatactg acagatctat
    16141 taagcacggg attccaagca ttgatggact tttctccagc tgtgtatggt gcagttctag
    16201 ggtttctttg gcaagtactg gtgattttcg gacttcattg gagtattatc cctcttgcga
    16261 ttatgcagct agcgcaaaat gggtggagtc agatgttagt aggcgtttat ggcgcgagtt
    16321 ttgcacagac agcagtggta ttggcgatgt atttcaagtt caaggatcaa aaaatgaagg
    16381 cgctttgcat gccagctgtg atttcaggaa tcttcggcgt aacagaaccg gctatttatg
    16441 gaatcacctt accgaagaag aagccattta tttactcgat gattggtggt gccatttcag
    16501 gaatctattt gatggcatct ggaacaatca gctacacaat gggcggatta gggatttttg
    16561 gggtggtaaa ctacatcacg gaaacagacg ccagtggtat gtttcaagcg tttatcggca
    16621 ttgctattgc ttcggtaatc gggttttcgc tgactttttt cttttggaag gatgaagcag
    16681 gtgaaacaga tgctatacag aaaaaatcag gtaaagaaat tgtaaaaaca ccgatacaag
    16741 gacaaatcgc tccactaaat gcagcgaagg atgcagcttt tgcacaagga acactaggtc
    16801 gaggaatctt gatctaccct gaaaaaggag aagtacgtgc cccttttgac ggaacagtca
    16861 tgaccctgtt cccgacgaaa catgcaattg gaatggtttc tgaaacaggg ctggaattgc
    16921 tgattcatgt cggattggat actgtgcagt tggaagggaa atattttgaa agcttagtgc
    16981 agcaaggaga aagagtgaaa caaggcgatc tgttgctacg cttcgacaaa aagaaaatcg
    17041 aaaaggaagg atacagttta gaaacacctg tgatcgtcac caattacacg gattatttgg
    17101 atattttgga aaaccaaggg gagacggtcg ggccagacga tgcacttatc accgcactga
    17161 cctgaacggt taggtgaaga atggaatagg cttaactatt ctttttattc cacttcttta
    17221 ttttcaaaat tgaaaggctc tttcatgatg gctgagctga tagggcgttt atcgaatttt
    17281 tgaccgacag aaattagatg gactaaattc tgttgataat tttctgcaaa aacacaacta
    17341 tataacacgt ctagaagata acaaattgat gtattgatcg taaaattacc aatttttgaa
    17401 tacagtcgct cgcgtgtcgt aagtcgcaaa gcggctgtac tcattgcaga tagcgttgaa
    17461 tcaccgatac tggtcaaagc taaaattgga acatgatttt gtttcaatat ttctgcggta
    17521 cgaagaatca ctttattttc acccgtataa gaaatcagga tcccgcacat atcgctcgtg
    17581 caattgtacg cttcatagaa tgattcacca aaagtggtga caattgtgac atccattttg
    17641 atgcgcttca ttttcagcat gaaatcttga gaaatcaaag tattcgagtt actggcgaag
    17701 atcacgattt tttttgcctg gagcagtaaa tacttggctt tttgcagttg gtcatgatga
    17761 atgagagaaa gtgtatcttg aatcgtcatc tgttctaaag aagccatttt atttgcgatc
    17821 gtcataatac cgtctgtggt ggaaaaagga agattcgcat ctacgtcttg aaaattccct
    17881 tcaagatagg ctgtttcagc taaaaaagca ttacgaaaac tgacccagcc atcaaaaccc
    17941 attttttttg ctacacggat gagtgtagac gggtggacat agcatcgctc agcgatctct
    18001 tggatggtca tttcgccaag tgctggagaa tcgcttaaga gaaactggat cacttcattt
    18061 tctgaaggag aaaaggagat ttctttgatt ttttcacgta ataacatgta gttaccttct
    18121 tcttattttt ttacgtaaat tataactttt ttgaaaatgt tttgtaaacg gatttatact
    18181 atataactta aaatagactt tttttgacaa gatatttaca aaaatccact agaaaacagt
    18241 aacttttgta aatgttactg gaaagaaacg gatttctatt gtttgttttg tttacaaaaa
    18301 agataatgaa agtgtaaaaa agtaaaggag tgagaacatg gcaaaaggaa tcaaaatcgc
    18361 tacgattggt ggaggcagca gttacacccc tgagttgatg gaaggattta tcaaaagata
    18421 tgaggaatta ccgatacgag aaatctggct cgtagatgta gaagaaggaa aagaaaagct
    18481 tgagatcgtt agtcagatgt ctcagcgtat gtgggatgct tctccgtatg aagtcaaaat
    18541 ctatgcaact ctggatcggg aagaagcatt gaatgatgcg gattttgtta cgactcagtt
    18601 tcgtgtcggt caattagatg cacgaatcaa agacgagcgg atccctagtt attatgggat
    18661 gattgggcaa gaaacaaatg gtgctggcgg gatattcaaa gcttttcgta ccgttccagt
    18721 ggtcttggca atcgttgaag acatgaagcg tttatgtcca aatgcttggc tgatcaattt
    18781 cgcgaaccca agtgggatgg tgacagaagc agttatcaga tatggcaaat gggataaagt
    18841 gattggatta tgcaatgtgc cagtaatggc gatgatgaca gaaccagcaa tgcttggcaa
    18901 gaaaaaagaa gagctgatct acaagtttgc cggtctaaat catttccatt ggcacaaagt
    18961 agcagataat aaaggaaatg accgcacggc agaattgatt gatcgtttat acgatgaaga
    19021 caatggattg ccgaaaaata tctttgatat cccgtttttc aaagaacaat taaaacaaat
    19081 gaatatgatc ccttgtggct accaccgcta ttactaccgt gaagaagaaa tgctggaaca
    19141 tgctttagaa gaatatcaaa cgattggtac aagagcgcag caagtgaaag aaacagaagc
    19201 agagctattt gaattataca aagatccaga attagaccat aaacctgaac aattgcaaaa
    19261 acgaggtggc gcttattatt cagacgctgc ctgtgaaacg attgcttcaa tctatggaaa
    19321 taaagaaaca cagatcgtgg tatctacaaa gaatgatgga gctgttcctg acctgccggc
    19381 agattgtgta gtagaagtca ctgcctatgt tggcgcacaa ggagcgagaa atgtagcgtt
    19441 tggttctctt cctgctgctg aaagaggctg gttgcaagta atgaagaata tggaattgct
    19501 gacgatcgaa gcagctgtga ctggtgatta tgggacagct ttacaggcgt ttacgatcaa
    19561 tccgcttata cgatcaggaa agacagcaaa acggatcatg gatgagttgt ttattgcaca
    19621 ccagcagtat ttaccgcaat tcaaggaaac aatcagccga ttaaaagaag aaggaatcga
    19681 agttcaagat gaactggcaa gagaattatc aggtaataca catataatgg aggaagtata
    19741 atgggattca gaaaagattt tttatggggc ggtgctacag cagccaatca atgtgagggc
    19801 ggttatgatg aaggtggacg cggactagca aacgtagatg ttgtgccaat cggaaaagac
    19861 cgttttcctg ttatcaccgg aaagaaaaaa atgtttgaat ttgatgagga tcatttttat
    19921 ccagcaaaaa ttgcaatcga tatgtatcat cgttataaag aagatattgc tttgtttgca
    19981 gaaatggggt tcaagactta tcgaatgtcc atcgcctgga gtcgtatttt tccaatgggg
    20041 gatgaaaaag agccgaatga agctggcttg aaattttatg aggatgtctt taaagaatgc
    20101 caaaagcacg gaatcgagcc acttgtgacg attacgcatt ttgattgtcc aatgcatttg
    20161 atcaaagaat acggtgcgtg gcgttccaga gaactcgttg gtttttatga aaatctgtgt
    20221 cgagtcatct tcaatcgata taaaggactt gtcaaatact ggctgacatt caatgagatc
    20281 aatatgatcc ttcatgcacc attcatggga gcaggactgt actttgaaga aggagaaaac
    20341 gaagaacaag tcaaatatca agcggcacat catgagttgg ttgcaagtgc catcgcaacg
    20401 aagattgctc atgaagtaga tccggagaac aaagtaggct gtatgctggc agcaggagca
    20461 tattatccat acacttgcaa tcctgaagat gtttgggctt ctagaaaatc agatcgagaa
    20521 aattatttct tcattgatgt tcagtcacga ggagaatacc cagcttatgc attgaaagaa
    20581 atggaacgaa atggcattca gatcgaaatg gaaccagggg atgccgcatt gctgaaagaa
    20641 catactgttg attttatctc tttttcttat tattcttccc gagtttcgac taccgacaac
    20701 gaactcttgg aacagactgc aggaaatatc tttgcttctg tcaaaaatcc atatctgcaa
    20761 gcaagtgaat gggggtggca aattgatcca ttaggcttga gaataacgat gaatgatatt
    20821 tatgatcgtt atcaaaaacc attatttatt gtagaaaacg gcttaggtgc agtcgatacg
    20881 ccagatgaga atggttatgt ggaagatgat taccgaatcg attacctggc agcgcatatc
    20941 caggcgatga aggatgcagt agaactagac ggagtcgatc tattaggcta tacgacttgg
    21001 ggatgtattg atttagtatc agctggtacc ggtgagatga agaaaagata cggattcatt
    21061 tatgtcgatc gtgataacca aggaaatggc acattagccc gttcaaagaa aaaatcattc
    21121 aactggtata aaaaagtaat tgattcaaat ggagaaaatc tttcgaacga ttgatcaatg
    21181 atttataaaa gtctattgtt tttcagcgga tttttcgagt ataataaagc tattcgagaa
    21241 acgcaagcag aacaatagac tttttttcgc attggctgta aagtatgctt acttgattaa
    21301 gtaaaggaga atctacatat gtatgatgta atcgttattg gcgcaggtcc tgctgggatg
    21361 actgctgctt tatatgcttc acgttcaaac ttatccgtat tgatgatcga acaaggtgcc
    21421 cctggcggcc aaatgaacaa tacggcagaa atcgaaaatt atcctggatt cgattcgatc
    21481 atgggccccg atctagctta taagatgtat gaaagtgtct caagatttgg gacagaaaat
    21541 gcttatggaa tcgttcaaga tatcaaggat cacggcagcc ataaagaagt catctgtgaa
    21601 gataaaagtt acgaaggaaa aacagtcatt atcgcaacag gctgtatcca ccgtaaatta
    21661 ggcgtacctg gcgaggaaga atttgctgga cgaggcgttt cttactgtgc agtctgtgat
    21721 ggtgcgtttt tccgtaacaa acgtctagta gtcatcgggg gtggggactc agcagtagaa
    21781 gaagccatct atttgacaca atttgcttct gaagtagtga tcgtccaccg tagagatgaa
    21841 ttacgtgcac aaaagatcat ccaagaccgt gcatttgcaa atgaaaaaat ttcctttatg
    21901 tgggatacag tcgttgacga aatcgttgga aacgaaatgg tagtgacagg tgtgaaagca
    21961 cgtaatgtca aaaccggcaa tgaatttgat ttagcagcag acggagtatt catctatgtt
    22021 ggactggatc cattaactgc accttttaga gaagcaggtt tgacgaacga agctggctgg
    22081 attccaacag acaacgaaat gaaaacgaat atgccaggcg tttttgccat cggagatgtt
    22141 cgtgaaaaag atttgcgaca aatcactaca gctgttggtg acggcggtat tgctggacaa
    22201 caagtgtata aatacttgga atctttagaa gaaacaactg cataagttta aaaagagtag
    22261 aagaacgggt tcaattgttc ttttactctt ttttttcgcg tgaaatttac tgaatctgat
    22321 ttatgcgaac acgtccaaca ccttttgata aaagaatcct ttcttgattt aagcgttttt
    22381 tggtcctcat actttcatat ctaataagtg aatgctatac ttattaagaa ccatatttca
    22441 gaaagaggtg ttattttcat gtcttgggaa caagtgtatg aacaatgggt acatgaagaa
    22501 aatttagaag aaaacttaaa aaaacaatta aatgatctgg gtgaagatcc tgaaaaactt
    22561 gaagatgctt tttatgcacc gttggaattc ggtactgcag gcatgcgggg aatcttagga
    22621 cctgggatca atcgaatgaa catctatacg gtaagacaag caacagaagg actagcacgt
    22681 ttcatggata cacaaggtga agaagcaaaa cgccgaggtg tcgctattgc ttatgactca
    22741 cgccatcagt caccagaatt tgcaatggaa gcagccaaaa cactggcaca tcacaatatc
    22801 ccgtcttatg tattcgaaag tctgcgtcca acaccagagc tttcttttgc agttcgtcat
    22861 ttgaagacgt ttgcgggaat catggtaact gcatctcaca acccagcggc ttacaatgga
    22921 tataaagtct acggagaaga tggcggacaa atgcctcctg cagacgcaga tgcattgacg
    22981 aaatatgtcc gtgaagtcag caatccgcta aaagtcgaag tattatctga cgaagaagct
    23041 aaacatagcg ggttgatcac gatcatcgga gaagaagtgg acgctgctta tctagaagaa
    23101 atcaaagcag tgacgattga tcgtgaattg gtagaaacaa tggggaaaga tttgaaactt
    23161 gtgtacacgc cacttcatgg aacagggaaa atgttgggcg aacgtgcgtt gaaacaagct
    23221 ggattcgaac aattcgtact agttcccgaa caagctgtgg cagatccaga tttcactacg
    23281 gtcaaatcgc caaatccaga agaacattca gcttttgaat atgctatacg acttggagaa
    23341 aaagaaggag ctgacttgct gattgcaaca gatcctgatg cagaccgttt aggcgcagcg
    23401 gttcgtttgc cagatggttc ttatgaagta ttgactggga accaaatcgg ggcattgttt
    23461 gctcaatata ttttggaagc acatcaatca agaggcactt taccagaaaa cgcagcggta
    23521 ttgaaatcaa tcgtttccag cgaattgcct acagcaattg cggaacacta cggtgctacc
    23581 atgttcaatg tgttgacagg gtttaaattc attgctgaaa aaatccaaca attcgaagaa
    23641 gaccattcac atacttttat gtttggattc gaagaaagtt atggttattt agttaaacct
    23701 tttgttcgcg ataaagacgc gatccaagca ttgcttttat tagcagaagt agcagcttac
    23761 tataaaaaac aaggcaaaac gttgtatgac ggcttgcaaa cgatttttga aacctatggc
    23821 tattttgcag aaaaaacgat ttctgtgaca atgagcggac aagaaggttc tgcgaaaatc
    23881 tctgctttga tggaaaaatt ccgtaaagaa gcaccgacag aatttgccgg agcaaaagtt
    23941 attcaaacag aagactttaa agaattgacg agaacagacc gtgaaggaaa cgtagaaaaa
    24001 ctaacaacac cgccatccga cgtattgaaa tatacattgg aagaaaatgg ctggattgct
    24061 atccgccctt caggaactga gccgaaaatc aagttttata ttggtgtaaa aggaagctct
    24121 acagaagacg cagccgaaaa agtagcctct tatgaagcga ttatcaaaaa gatgacagaa
    24181 gaataaaaaa cttgagactg atggaaaaag tggtaaactt tagaagtcag tcttttttca
    24241 agttggaggt gaatggattg ccagacacgc aaaaatcaaa agtagagaaa gtcagtcaat
    24301 tattcaaaat gttgagtgat cccactcgtc ttaaaattct gctatatctg aaagacgggg
    24361 aacaaaatgt gacagcaatc acccaagcag tggaaatgga gcagtctgct gtatcgcatc
    24421 aactacgttt attaagagaa aatcatgtcg tcaagtctca tcgcgaggga aaagcgattt
    24481 tgtatagtct tgatgattct catgtactgg atattttgaa ccagacactc aaacatgtgg
    24541 aacatcaata acgataggtg caaatagata aacactggag tgtgacaacg aaatttcttc
    24601 gttgtcacac tccagtgttt tttaagaaaa agacaaaaat gattaatcgc ttttttctgt
    24661 tgtttcagtt ccataataac tatgatcttc taggtctaaa gcattcaaaa taagcgaagc
    24721 cgtttcttca atagataaag atgccacatt gatcactaca catcctagtt tttcataaag
    24781 atcattcgca aaatcgagtt cagctctaat tttttcgata tcggaataag cagtatcagg
    24841 gtttaatccg taagagcgca tccgttcttt acggatatta tttaaaatat ctgggttatt
    24901 cgttagtccc acgatttttt taggatcgat ctcccaaagc tgtttgggaa tatgtgcttg
    24961 tgggatcaaa ggtaaattgg caacttttaa atttttgtta gctaaaaaca agctcaaagg
    25021 cgttttggaa gttcgggata cgcctagcaa aacgacatct gcttctaaaa aaccacgagg
    25081 atctttccca tcatcgtatt ttacagcaaa ttccattgct ttgatccgtt tgaaatagtt
    25141 ctcattcaat aaatggaggg caccaggttg ccgaattggc ttgataccgg ttaaacgttc
    25201 aatttctgat atcggtggcg tcatcacatc aaaactaaat aattgatgtt cttcacaaaa
    25261 agaacgtgtt atctcgatca gttcttgatt gattaatgta tgcaggacaa gtgctttttc
    25321 ttctaatgca tcttgcaatg cctgctttaa tgttttttca tctgtcacga acgttctgcg
    25381 gaataggttg aactcaacgg taggatactg agccatagta gcttgcgcta gttttgtcgc
    25441 agtttctcca gcagagtcgg agatgacaaa aaaagtaacg acttctgtag aatcggaaga
    25501 catggataaa acctcacttg catttttttt atgtttatta taccatactc tagaatgcgt
    25561 acttcgtaat cattttgatt tggaggaata agtcatgaaa aaacagacat tgatcgaaca
    25621 atcattagaa acattgaaaa ataacggttt taaatatact aaaaaaagag aagcattgtt
    25681 aacttattta gtgaagcgta accgctacgt atctgctaaa gaagtttttg actatatgaa
    25741 tcaggaattc aaaggggtaa gttatgatac gatttatcgg aatctccatg attttgcaga
    25801 gatcgattta ctggaagaaa ccgatttaaa tggagaaatg aagtttcgtt ttcattgctg
    25861 tcagggggaa atcggccatc accatcattt tatctgtaca gtgtgcggaa caacgaaaga
    25921 aatccatatg tgtccgatga attatttcga agaacagcta ggtggatgca cgatcgaagg
    25981 gcatagattc gagattttcg gaagatgtga aaattgtcaa taagggtata aataaaataa
    26041 catttgataa ttttaaaaaa aagcaagatt tccttgacgg tcaaaacagc attagatata
    26101 atatttacag gacagtcttg ttttttgaga tatatttcaa taacaattac ggttactttt
    26161 taagctcgga gggagggaat taacatgtca aaaacagtcg ttcgcaaaaa cgaatcactt
    26221 gacgatgctc ttcgtcgctt caaacgttcc gtgtcaaaag cgggtacttt acaagaatct
    26281 cgtaaacgtg aattctacga aaaaccaagt gtaagacgca agaaaaaatc tgaagcagct
    26341 agaaaacgca aaaaattcta gttctgtgat gaattggagt tggtagtgtg tcactactaa
    26401 gtagattaaa cgatgacatg aaagcagcga tgaaagcgaa agataaggaa tctttacaag
    26461 tcatccgaat gatcaagtca tctatacaaa acgagcagat taaagaaggt cacgacttga
    26521 cagaagaaga agaactaacg gtgttgtctc gcgaaatgaa acagcgacgt gattctttgc
    26581 atgagtttga agaagcagga cgtgacgatt tagctgaaaa agtaaaaagt gaaattgtaa
    26641 tagtcgaaaa atatatgccg gaacaacttt ccgatgaaga aattcgacaa cttgttcaag
    26701 aagcaatcac tcaaactggt gcttcatcaa tgaaagaatt tggcaaagtt atgggtgcaa
    26761 ttatgcctaa agtcaaagga aaagcagatg gaaaccaagt gaatgcgatt gtgaaagaac
    26821 tattacaatc ttaattttat catttaaact gcggacagtg attgtccgca gttttttgtg
    26881 ttcgtaaaaa aagaa
//
LOCUS       DAPBCF010000036        25501 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.036, whole genome shotgun sequence.
ACCESSION   DAPBCF010000036 DAPBCF010000000
VERSION     DAPBCF010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25501
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.036"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            133..3660
                     /locus_tag="RD508_001866"
     CDS             133..3660
                     /locus_tag="RD508_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HDT7736425.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="RD508_001867"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="RD508_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HDT7736426.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="RD508_001868"
     CDS             7448..7789
                     /locus_tag="RD508_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7736427.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="RD508_001869"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="RD508_001869"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDT7736428.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="RD508_001870"
     CDS             9146..11566
                     /locus_tag="RD508_001870"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDT7736429.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="RD508_001871"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="RD508_001871"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDT7736430.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="RD508_001872"
     CDS             13000..13737
                     /locus_tag="RD508_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7736431.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="RD508_001873"
     CDS             13751..14566
                     /locus_tag="RD508_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDT7736432.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="RD508_001874"
     CDS             14579..15226
                     /locus_tag="RD508_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7736433.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="RD508_001875"
     CDS             15242..15898
                     /locus_tag="RD508_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7736434.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="RD508_001876"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="RD508_001876"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDT7736435.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="RD508_001877"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="RD508_001877"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDT7736436.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="RD508_001878"
     CDS             18240..18758
                     /locus_tag="RD508_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDT7736437.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="RD508_001879"
     CDS             18865..19365
                     /locus_tag="RD508_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7736438.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="RD508_001880"
     CDS             complement(19645..20565)
                     /locus_tag="RD508_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HDT7736439.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20730..21743
                     /locus_tag="RD508_001881"
     CDS             20730..21743
                     /locus_tag="RD508_001881"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HDT7736440.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="RD508_001882"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="RD508_001882"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HDT7736441.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="RD508_001883"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="RD508_001883"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDT7736442.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="RD508_001884"
     CDS             complement(23383..24144)
                     /locus_tag="RD508_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7736443.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="RD508_001885"
     CDS             24333..25427
                     /locus_tag="RD508_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDT7736444.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8448 a         4424 c         5383 g         7246 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa atagccagtt atttctgctt ttttattttg tttttttata
    25501 g
//
LOCUS       DAPBCF010000037        24566 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.037, whole genome shotgun sequence.
ACCESSION   DAPBCF010000037 DAPBCF010000000
VERSION     DAPBCF010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.037"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            76..1380
                     /locus_tag="RD508_001886"
     CDS             76..1380
                     /locus_tag="RD508_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDT7736445.1"
                     /translation="MLNDINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLS
                     QNSLFLKTCLLYLEEDEPDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPR
                     FTEMERRLLLLNVSYRLGGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILLI
                     GFAISFLRQQVCAVTIDSKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLF
                     NLCNYGFHSYQLIAEDFQQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIH
                     LMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVI
                     ELSGILRLTKEHLTIYIVTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQ
                     QSSNRVLCERTLYTPDAVQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1472..1837)
                     /locus_tag="RD508_001887"
     CDS             complement(1472..1837)
                     /locus_tag="RD508_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HDT7736446.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1834..2199)
                     /locus_tag="RD508_001888"
     CDS             complement(1834..2199)
                     /locus_tag="RD508_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HDT7736447.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2391..2639)
                     /locus_tag="RD508_001889"
     CDS             complement(2391..2639)
                     /locus_tag="RD508_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736448.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2638..2766
                     /locus_tag="RD508_001890"
     CDS             2638..2766
                     /locus_tag="RD508_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HDT7736449.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2823..4517
                     /locus_tag="RD508_001891"
     CDS             2823..4517
                     /locus_tag="RD508_001891"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HDT7736450.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQ
                     EEEHVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4521..4640
                     /locus_tag="RD508_001892"
                     /pseudo
     CDS             4521..4640
                     /locus_tag="RD508_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            5168..6301
                     /locus_tag="RD508_001893"
     CDS             5168..6301
                     /locus_tag="RD508_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HDT7736451.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQNGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYE
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6332..6652
                     /locus_tag="RD508_001894"
     CDS             6332..6652
                     /locus_tag="RD508_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HDT7736452.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6681..7145)
                     /locus_tag="RD508_001895"
     CDS             complement(6681..7145)
                     /locus_tag="RD508_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7736453.1"
                     /translation="MVTYNWIKLREHPELVKQSAKWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7274..8523)
                     /locus_tag="RD508_001896"
                     /pseudo
     CDS             complement(7274..8523)
                     /locus_tag="RD508_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(8552..8869)
                     /locus_tag="RD508_001897"
     CDS             complement(8552..8869)
                     /locus_tag="RD508_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDT7736454.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(8895..9215)
                     /locus_tag="RD508_001898"
     CDS             complement(8895..9215)
                     /locus_tag="RD508_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7736455.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDIINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9616..10572)
                     /locus_tag="RD508_001899"
                     /pseudo
     CDS             complement(9616..10572)
                     /locus_tag="RD508_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            complement(10617..11743)
                     /locus_tag="RD508_001900"
     CDS             complement(join(10617..11515,11515..11743))
                     /locus_tag="RD508_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDT7736456.1"
                     /translation="MTRYEENFKQMIIELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIILKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(11824..12282)
                     /locus_tag="RD508_001901"
                     /pseudo
     CDS             complement(11824..12282)
                     /locus_tag="RD508_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            complement(12298..13614)
                     /locus_tag="RD508_001902"
     CDS             complement(12298..13614)
                     /locus_tag="RD508_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7736457.1"
                     /translation="MRGSGMSFMDKLAKVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISYLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVLNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(13764..14462)
                     /locus_tag="RD508_001903"
     CDS             complement(13764..14462)
                     /locus_tag="RD508_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDT7736458.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNIA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNVLAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(14751..15711)
                     /locus_tag="RD508_001904"
                     /pseudo
     CDS             complement(14751..15711)
                     /locus_tag="RD508_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
     gene            complement(15825..16658)
                     /gene="msrA"
                     /locus_tag="RD508_001905"
     CDS             complement(15825..16658)
                     /gene="msrA"
                     /locus_tag="RD508_001905"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDT7736459.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDTRENISVKEQ
                     LSKLEVTLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQDERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(16892..17635)
                     /gene="truA"
                     /locus_tag="RD508_001906"
     CDS             complement(16892..17635)
                     /gene="truA"
                     /locus_tag="RD508_001906"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDT7736460.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYRS"
     gene            complement(17826..18461)
                     /locus_tag="RD508_001907"
     CDS             complement(17826..18461)
                     /locus_tag="RD508_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HDT7736461.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(18608..19849)
                     /gene="sstT"
                     /locus_tag="RD508_001908"
     CDS             complement(18608..19849)
                     /gene="sstT"
                     /locus_tag="RD508_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HDT7736462.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEPT
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            complement(20170..20847)
                     /locus_tag="RD508_001909"
     CDS             complement(20170..20847)
                     /locus_tag="RD508_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HDT7736463.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATIATTTTTSTESKPTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSESSEQVEQTLWNADKSAQLEAFMA
                     TWGQTMGQQYKSYTNQMSVDLYGLKVPQVILNGEWKMAIGGVPVSAEWSESGTGQADY
                     QITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELKNG
                     FNQIVYG"
     gene            complement(21098..21640)
                     /locus_tag="RD508_001910"
     CDS             complement(21098..21640)
                     /locus_tag="RD508_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDT7736464.1"
                     /translation="MNIVEEKFAQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLKQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(21645..21872)
                     /locus_tag="RD508_001911"
     CDS             complement(21645..21872)
                     /locus_tag="RD508_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDT7736465.1"
                     /translation="MKKMIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSTKVKEA"
     gene            complement(21951..23831)
                     /locus_tag="RD508_001912"
     CDS             complement(21951..23831)
                     /locus_tag="RD508_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDT7736466.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIIIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDNVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDQFSQYYTPTVLLIALLVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQRGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAMLKQAGAKHLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLH
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSSFGSLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLIGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            24117..24452
                     /locus_tag="RD508_001913"
     CDS             24117..24452
                     /locus_tag="RD508_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7736467.1"
                     /translation="MGVEAVDKYLYLLAGNKIQKSLMDFIQELECTFHKKFTHSILLK
                     LLIHTACLIERTLINGHELKIISEDDTRPSHETIFHVKKAFKNIETEFGITVSYDECF
                     FIYDIIASK"
BASE COUNT         7583 a         4998 c         4131 g         7854 t
ORIGIN      
        1 tgtgggcaat tctatgtaaa taaagaagtc aatctagaaa agctctccaa tctcctgcat
       61 gtttgcaaaa ccactttgct caatgatatc aataacataa aaaaagaatt tgaagaacag
      121 atcgcttata cacatcggga aaaggaccgt tacactttat atttttcaga acatatacct
      181 cgatgcaaga tcatgcagca attgtctcaa aattcgttgt ttttaaaaac ttgtctgctt
      241 tatttggaag aagatgaacc tgattatctt caattaactg aatgtgaatt catctctgtc
      301 agcaaagctt attcattaaa aaaacaagta ttagcttatt ttaatgactg cgggatcgaa
      361 atcgaccgct actcccctcg attcactgaa atggaaagac gtctgctgct tcttaatgtg
      421 tcgtatcgtt taggcggttt taattcttgg gagctacctg aatcgttttt tgaacgtgcc
      481 gatcgtttca ttgaatccgt aacggaaaat agtggcagat tttatgataa agaaaataaa
      541 gaaatcttat tgattggttt tgctatcagt ttcctacgcc agcaagtgtg tgctgtgaca
      601 atagattcaa aatttatcga agaaatcaaa aaacgtccta tttacaatta tgtcgaatca
      661 gcatgggaaa acactgattt ccaaacctat tataaaaaag aagaattcgc ctttattttg
      721 acactattca atctttgtaa ttatggtttc cattcttatc agttgattgc ggaagacttt
      781 caacagctac accaagtgtt tattgacaat actcccgaaa taaaagaact agttgctacc
      841 tttgaatctc acttcaatca agaattattc ggaaaccaac cattcgaacg tgcgctgatt
      901 catctgatgc gttcggcttg ggataactat caattattca tgccagaaaa attttatctt
      961 ctaaatgagg aacagacaaa tttatataaa gaagtccaga caattttttc cagctggtcc
     1021 agccagttac cttatgatct acggttgaat cctaattgca tgcgggcttt tgtgatcgaa
     1081 ttgagcggaa ttctccgtct gacaaaagaa catctgacta tctatatcgt cacaaattcg
     1141 gatgttcatt atctgattta tcgggaagcc ttggaagctg taactacttt cgattttcaa
     1201 gttgcaccaa caatttattc aagtatatct gatataaaga agtatgcgca gcagtcctca
     1261 aaccgggtat tatgtgaacg tacattatat acaccagatg cggtccaata tgaaaatatt
     1321 attcctattt cgatcaatac gatcgatcga gctatcattt cagctgtgca aaacaaataa
     1381 gggactgtga caaaaatcat gtcacagcct cttatttgtt gaagatgccc atttctgtaa
     1441 caatctcttg atacacatca ggctcacaac ctcacttatt ttggacatct acgggtccga
     1501 tctctttatt taaaaaataa gaaatgatgg ttcggataac taccaacgcc gctagttgga
     1561 aaatatcctg caaggtaggt ttgataatcg attcgatgat cccagctgaa acaagaattt
     1621 ccaaacttag aagtatatag cctcccaaca tctttttaat agcattgttc tcgctgactc
     1681 ggtcgctttg cacttttgta tggacaaata aatatttcaa aaaatccttg attgatagac
     1741 aaacacccca aaccaataaa cagatagcaa agatatcaag tcccagtaca agtttttcaa
     1801 aatatggaag aagaaactgc atcaactctg tcgtcatcct acctctcctc ttctttgttt
     1861 ttctttgtct tctatttcct gattcaagaa ataagaaatg actgttcgaa tgataataat
     1921 aagtgcaagc ttcaaaatat ctgtccaagt cggcttgata actgactcga tgatatcagc
     1981 aacgactagt acttccaagc ttaacaaaat ataacttgct agcagttttc ttgtatctgc
     2041 attacgagta ttacgttctg catagttttt cttgacatga gaccaatcaa aaagtttgaa
     2101 tagaacaaga acgatcccga caattaagat accgatagaa caaatattta aaatagcaat
     2161 gatccattct agaaattcaa ttaaatttga gcgaaacata tacgctacct actttctttt
     2221 aatttgttcc tattctttta ttgtaaaaga aagttacctt gttcgtctat ttaaaagttg
     2281 ttctaatgat aacggttcgc ttaaattttt ctttttcact ctcccctttt tctccctcca
     2341 tccataaatc gtggaagtat ccaaaacaac gtagcaagtt aaaataaggc ttagtccgtc
     2401 atcagctttt caaagaagca ctgtctcggt gctttttttg tacccaaatt tctaaaaata
     2461 gaaccataca cctcctcaaa tcttttcttc ttacctaccc tatttttatt tacaggaaaa
     2521 tcagacactt cttctttttt gtcaaaattt cctttttctt ctcgtcctat catttggcat
     2581 tctaataaaa acgaactatc cttggatata gaaagagaaa acaaggaggc gtttttcatg
     2641 agtaaaaaat taatcaaagt cggcatcggt ttaggtttgc ttgcccttgg cgctgcatat
     2701 ctaggaaaaa agacaggact attcgaagat gacagtcatt tatatgatga attcgaatca
     2761 atctagcatc ctatttagtt gaatcactac ggacatactt ggaagacatt ggaggaatca
     2821 caatgagaaa aagtaaagca ataatgattg gtgccggtat tgccaatatg gcagcggctg
     2881 tttatttgat tcaagaaggc aaatggaaag gggatcagat caccttttat tcattggatg
     2941 atcacggttc aaatgatggt gcaccgaccg acactgtagt ggatgaatat tggaataaaa
     3001 accatccatt agaaaaccaa aaaggctata ttgctcgagg cggtcgcatg cttaattacc
     3061 gtacctatgt agatttgatg gatctgttaa gtcgaatacc ttctgttact gagccaggga
     3121 tgactgctga agaagatacg agagattttg atgcaaaaca ccgaaccttt gacaaagcac
     3181 gtttgatgga aggtggcaaa ggaatcattg atggcggaaa actgggattc aataataaag
     3241 accgtattct tctgactaaa ctgattgcta tgcctgattc agaagaagaa aaactagaca
     3301 atatcactat cgaagaatat ttcaaagatg atccacactt ttttgaaaca aacttctggt
     3361 ttatgtggga aacaacattt gctttcagaa cacgtagttc tgctcaagaa ttgcgtcgct
     3421 atatgcatca aatgatttat gaattcactc aaatcgaaca tctagtgggc gtcaatcgaa
     3481 cacgttacaa tcaatacgaa agtattatgc ttcctttgat cgagtacttg aaagaacaag
     3541 gatgcaaaat cattttgaac cgccgtgtca ctgactggga attcaaagaa acaccgatgc
     3601 aagatgaaat cactgtgact ggtttgaaaa tgaccaatac actgactcaa gaagaagaac
     3661 acgttgtggt cgatgaagat acagcagtta ttttcactaa tgggtccatt acagattcag
     3721 ctactttagg agattacgaa acaccagctg tagaaaatat ggattatggt gcagcttcta
     3781 gtctctggaa aaaagccagt gaacgtttct acaacttggg aaatcctgac aaattctttg
     3841 ctgatcgaga tgcaagcgaa tgggtcagct ttaccctgac gacgaaaaac catttgttgt
     3901 tgaatgaaat cacccgtatc acgactcaag aaccaggaaa tgccttgaat tcatttattt
     3961 caaccacacc gatcacgccg ttaggccaaa aagatgtcaa tatgtctatc gtcgtgcatc
     4021 atcaaccgca ttttacgtct cagaaaccaa atgaaacagt tatttggggt tatttccttt
     4081 atccaagacg acgtggcgaa tttgtggata aacagtatat taaaatgaat ggaaaagaaa
     4141 tgctagaaga actgattgga caactttcaa aagtagatcc tggaccagtg aatattcgtg
     4201 aaaaagaaac agaaattttc gacagcgtaa taaataatat ccctgtctat atgccttatg
     4261 cttccgcgtt gttcaataat cgtgccaaaa gcgatcgacc aaaagtcatt cctaaacatt
     4321 cgaccaatct ggcctttaca ggagaatttg tcgagcagcc ttatcagatg atctttactg
     4381 aacaaagtgc tgtacgttct ggagaaatcg ctgctttcca ttttgcgggt atccctatgt
     4441 cacgtcttgt caaaacaccg cgttacgaca aagatattcc tactctagct cgtgccgcaa
     4501 aaaaaatgtt tgaataatca agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa
     4561 caaccaggct aaaacagctt cttatgtttt tgatttggtt ggacttatta ccgcagatgc
     4621 aagcttttga acaccgttta ccaagaggtt gtgaaaaagc tgccctgcat caagtaataa
     4681 gagcagccaa gctaaaacag cttcttatgt ttttgacttg gttggactta ttaccgcaga
     4741 tgcaagcttt tgaacaccgt ttaccaagag gttatgaaaa agtcgtttag tttcgagtat
     4801 gaagaaaaat tttgtgaaaa tggttcctca cgtttttgca taaatttgac ttaataccga
     4861 gaaactgatc ccttctgtca taacctcttt ttatttatgt ctgtttcttt ttgaaaacaa
     4921 ccattttttc aacgtttact ctcttgccaa tccaacatca tctaacagat acaactattt
     4981 caatgattac cattacacta aaaaatcgga aactcacctc tccgaacaca aatacataag
     5041 actatagaat gtttcattta agaaaaaaag cgtttcatta tcaaaaaggt aagatctcct
     5101 ttaaaatgaa attatctgta gtactaataa tgcagacaat tttatgaatc tgaaaggagc
     5161 atctccaatg aaagcagtca cttggcaagg aaaacagaaa atggaaatca gaaacgtaga
     5221 tgatccaaaa atattagaac caacagatgc aatcatccgt atcacagcaa cagccatttg
     5281 cggctccgat ctgcatcttt accatcatgg tgaagcagtt ttggaaaaag ggtatgttgt
     5341 aggacacgaa ccaatgggaa tcgttgaaga agtgggatct caagttcaaa cattgaaaaa
     5401 agggcaacgt gtggttatcc cttttaatat tagttgtggt cattgtcatt tctgcctgaa
     5461 tcacatggaa agccaatgtg atgaatcaaa tccagatcag ttatatggcg ggcttttcgg
     5521 atttggcaag ttgaacggta atcattgggg tggtcaagcg gaatatctaa gagttcctta
     5581 tgcagactct acttcatttg ttgtaccaga taatgatctt cctgatgaaa aagttttatt
     5641 tctatcagat attttgccca cagcttattg gagcgttgaa aacgcaggag taaaaaaagg
     5701 cgatacagtt gtgattctag gttctggtcc agtcggtcta ttcgctcaaa aattcgctgt
     5761 tatggctgga gcagagcgcg taatcgcagt agatccagta cagcaccgtc tagataaagc
     5821 ggctaattac aatggggttg aaacttattt cttagaagac acggcacaag ctggaacaga
     5881 attgtatgaa ctggctaaag gtggcgcaga tgtcattatc gattgtgtag gaatggacgg
     5941 attagagcct gtcaaagaaa aagcgaaaaa tttagtaagc ttacaaaacg gcacaatctc
     6001 tccattacag atggcatcgc aagctgtcaa aaaatttgga acagtccaag taactggtgt
     6061 ttatatgact ccagcttctt cttacccgct gcaagaattt tttatgcggg atatcgctgt
     6121 caagcatgga caggcaccaa ttatccatct aatgccaaaa atttacgaaa tgattgcaga
     6181 aggactattc gatcctacac aaatcattac tcattcgctg ccactatcag aagcagcaca
     6241 agcatatgag atctttgaca aaaaagaaga taaaaatata aaagttgttt tgaaaccttg
     6301 aattcagtaa aaaatacagg tgattttctt tatgcccaaa atcaaacgaa atacccatga
     6361 gatcgaaata ggaaaagaag aagatatcga aatacgagga cgtcgcttcc gcttctattt
     6421 ccaaaatcgt tacacattga tctcactggc tgtcgattta ttaaccggga ttttctatat
     6481 ttttggaagc cttgcttcct taactaaaat ccccgatcga tatggcacct atttttattt
     6541 ggctggtgct attttcttga cgattcgtcc tattctcaga atcgtaagga acatttttat
     6601 ttacgacgaa aaaaaagcaa tgaagagaac aagcaaaaaa aaagaggcat gagatttgaa
     6661 aaaatctcat gcctcttttt tcaccctatc gtatcacttt gatacagacg agcggtcgtc
     6721 ccactttctt ccttgaccat tgtcaaaaat gtccactcgt atcgttcata aaacgtggta
     6781 tgatctgtaa ttaagtaaag tttttcgtac ccaagttgat gcatttcttt tctgatttcc
     6841 gctaatatcc gcttggctat cccctgctta cgcttttccg gttcaacaaa cagggcacaa
     6901 agatttggtg tcaaatcagg gcggttatgg aagtcgtttt caataacgcc cgctcctccg
     6961 acgatggttt ctttttcatc taagaccaca taccattgag gaatactttc cttattagcg
     7021 attccagtac gaatactttc ctcatacaca acagcaggaa ctccccattt tgatgaaaac
     7081 cacttcgcac tttgttttac taattctggg tgttctctta atttgatcca gttatatgta
     7141 accaatgttt aaacctccga ctaaaataaa acgtttacaa aaattataca agtctttatg
     7201 aaaattagca atgacaacaa tagtgatgta aaaaaaacgg aaaacaatca cttgttctcc
     7261 gttttttgat taatcaagca tctaaagctt cttttcttct ttcttggatc gtagctacct
     7321 tgacgaacgg tagatagatc aaaatagaaa gaaccaaatt gacagcggct agtacaccac
     7381 ctgcaatact ttttgttgcc aatacaccgc caataattgg tggagttacc catggaggca
     7441 taacggtagc tgctggcact aaacctgtag aagtcgcaaa gtaagcaaca ctaactaaga
     7501 ccattggtgt caaaataaat ggaatgaaca tgatcgggtt caacacgata ggtaacccaa
     7561 acatcgttgg ttcattaata ttgaagacac ctggcgcaat cgacaagttt gttacaacca
     7621 tatatggttt gtttttacgt cctactaaat aaatagctaa cagtaaacct aaagttgcac
     7681 ctgttcctcc taagttgaca aagctgtcaa agaaaggttt gttcacgata aacggtgcgc
     7741 tatgtccagc tgcgattgca ttaacgtttg cttcaatggc tggcgcattg attgtttgca
     7801 tcaaaggatc gaccatattc gctccgtgta aaccaaagaa ccataagaat ggtgtgataa
     7861 atgcaagcag taaggcagat ggataagagt ttgcaagtcc cataaatggt tcttggacca
     7921 ctgtatagaa agaacctacg atatcatcaa caccgaatgc agcaaaaatt gcagcaacta
     7981 aagcaaacgc agagatagtg atcattgctg gtagtaatga agcaaatgct tttgcaactg
     8041 ccggtggcac accatcaggc attttgatga tcaatttttc atttccgctt aaacgtacaa
     8101 agatttctgt tgaaataatc ccaacaataa tagcaataaa caaaccgttt gagctcatac
     8161 ctaatgctcc gcctaaagcg aagaaagagc ctaaagaaat cacacctgcg gaaacaccgt
     8221 cttttcggta gccgttagct aaatgataag caagaaagca atcaagacag aaagaatggc
     8281 aaatgtaccg ttccaagcag cagccccgaa tcctttccat gattcaccac caaaaattga
     8341 gttcatcaat tcttggaacc cgggaatcgg taagttattg atcattactg ctaatgctcc
     8401 taagatcatt aacggcatac tcaccataaa tgagtcccga atcgcaacta aatgccgttg
     8461 tgcaccaatt tttgatgcta caggtataaa atgtttctcc ataaatgcaa caaatttatc
     8521 cataaatctt ccctcttttc tttactgtag attacgcgtt caatcgacga tacagatcaa
     8581 tgatctcttt tgctaaatct gtaaaagcta tggatgtcat cagatgatct tgactgtgga
     8641 ctgtcaaaag cgtgacttca acgtgatttc cttgtgcttc ttgtgtcagc atctctgttt
     8701 gagagtgatg tgcttggact aaagattcct ctgcatcttt gattttttca tctgctaaag
     8761 tgaaatcacc ttttttcgca gcagcaatcg cttccattgc atcgcttttt gcatttccgc
     8821 caaacatgat cagacccatg atggcttcta gatttttttg atcttccatt tattgtatcc
     8881 tccgataatt tttattattt gtttattagt ttttctgctt ggtcgagtac tttttcacca
     8941 ttcatcatgc catagtcagc catattgatt atatctaaag gaatgccttt aggtgctagc
     9001 ttttcagcaa attgattttg cataaagcgt acttgcggtc ctaaaagtaa aacgtctaca
     9061 tttttagatt ctagttgatt atccgcatct gaagcagata cagcaaagat gtctgcttcc
     9121 attccttttg cttctgctgc cttttgcatt tttgtgacta ggagacttgt actcattcca
     9181 gctgaacata caagcatgat tgttttcttt tccattttaa acacgttcct ttctatactt
     9241 acacttgtat ataagcaagt agcgtgccaa ctttgaaagc gctttaaaaa gttgatatca
     9301 tcacatttaa ggtctatacc aagttgcata cacactaaaa aagaaagtgc acactaaaca
     9361 cacaaattaa tttttattac cttttttctt ttaacgtgca caaaaaaagt tgtgacacaa
     9421 aacttgtcac aacttttttt cgaataaacg gtattcaaaa gcttgcatct gcggtaataa
     9481 gtccaaccaa gttaaaaaca taagatgttg tttttacttt gctattctta ttacttgatg
     9541 caggacagct ttttcacaac ctcttttatt tcaaataacc agtaaataca atgaacatct
     9601 acaaaaaact tctatttatt tatagatttc gtcaggcaaa tccaattctc tcttatcaat
     9661 caaagtctga taccacgaag cagatttttt caatgttctg cttcgttcat cgttcaattc
     9721 gattcgaact aatccatatc gattcttaaa tgcattcatt ggtgacacac agtcagtgaa
     9781 tgcccataac atatagcctt cgcaatttgc gccttcttct gttgctttga tcaaataacg
     9841 caaatgctgt ccgataaatt cgatacggta atcatcttgc acgattcctt tctcatccat
     9901 ataccgttct tcatgttctc ttcccatacc gttttctgtt atcagccaag ggatattatg
     9961 ataattttct tttagataca tggctatatc atacatgatt ttcggataga tttcccatcc
    10021 cctggaatta ttcattttct tcccaggtaa atcaaagact tcataatatc gttctggatg
    10081 gaaaggtgtc tcttcattcc attgataacg aggagcgcga acgcgtttag gataatattg
    10141 attgattcca aggaaatcta ctgtatgatg ctgaatcgtt tctaaatcct ctgttgcagg
    10201 atcgaaataa atcgattgtt tttgacacaa ctccaggaac tcttctgtgt agtacccttt
    10261 taccatcgga tcaaaaaata ctcgattata aaacaaatca tacatataag cagctttttg
    10321 gtcttctgga gaattagatc gagcatagac catttcagga tttaaaatac agccaatcct
    10381 tccaccataa tttccgctgc ggtaaatctc tactgcttta gccgttgcta aaactttatg
    10441 ataattccac atcatccact tttttgtgtt ttgttcatgc ggccagcgaa cagcatccaa
    10501 atagcaacgc gtttggggaa cgattggttc gttgaatgta aaccagtttt ttaccctatc
    10561 accgtaacga tcaatggatt tgagtcaata tcttggacac attttagtag agacggttaa
    10621 gccatttttt cttttgctaa ttcttcaaat tcctgtgggg ttagatagtg aatcgagcta
    10681 tggattcgat ttcggttata aaatccttca atgtagctaa atagcgctcg atttgcttct
    10741 tcaaaatctg agtagctagt cgtgtagact tcttcttttt tcaatgaggc atggaaagat
    10801 tcgattccag cattatcata aggtgttcct tttctactat aagaatgcct tattttgttg
    10861 gttttaagcc attgttccac ttctcttgct gtgtattggc tgcccaagtc agtgtgtaga
    10921 atcattcctt ctggaatgtg ataatgtatt tttgctttat tcaatgtttg aatgacacaa
    10981 tccacagtca ttcgttttga aaatgtataa ctaataattt ttttcgtgtg taaatccatg
    11041 attgaagata agtaacacca accatttttc ttagtaggaa tgtacgtaat gtcagctgcc
    11101 catttctcac agatcgtttc agtagaaaag tcctgattta agagattctc ttttaaaatg
    11161 atcggtttat tagacctttg aggtctatat tttttaacta caatcgacct taaatttaat
    11221 tgtttcatta gcttttggac atgtttaaga gatactgaaa tcccttcttt taataaaact
    11281 tgatggatct ttgtggcacc atagcgttgt ttattcgtaa aaaaaattgt tgaaatcttc
    11341 tttttcaact tattatttct gatttctgta gctgtcaacg gtttattctt ataaaaataa
    11401 tagacacttc tagggatttc taataaccga cacaacaaag aaacagtgta atccttacac
    11461 catttttcaa taaattgaac aagcgaattt aggttttccg agagaatatg gctgcggctt
    11521 tttttaagat ttcaagttcc tcatttaaac gagcattttc ttttctcagt tcagctactt
    11581 cttttccagt cagtcctgtg gactgatcag gtaaatataa attcttccat ttgtaaatcg
    11641 ttgcttcaga taagccatat tctttcgcta accctcgaac agaacgtcca gtttgattca
    11701 gttcaataat catttgttta aaattttctt catatcgggt cataaaaatt catcctctcg
    11761 tagataagtt taatttattc ttgtctctac gaaaagctgt ctaagatttg atactaacac
    11821 cacaaaggca atttgagcat acttagcata aaaatcaact acttttcttg aagaccagcc
    11881 atcatatttt tccaaaagaa aagctgggac ttcataatgt tccaaacaaa tcatcggttc
    11941 tacgtctgct tcgatcaaag agtcgatcat ttcacttata tgctgagcat attcttcatc
    12001 tactatacag ttctcataat cagtaaaaaa acgagcccaa ttgatagaag tccgataatg
    12061 tgtcagatgg atggatttca tcagatccac atcctgctgg tattgttcca taaaattagt
    12121 tgctacggct gggccatacc cattatgcca aacaaaatgt tcatttttat accagctatc
    12181 tataaacgaa tcctgtcctt ctttttttcc tttccaacct tccgtttgcc aagcagaaga
    12241 tgcagcacca agaataaaat tttttggaat agtaattttc atgatttcct cctgttttta
    12301 gatcccatca ttttccacac gatttgctac ttttacaaat ggcagataga tcaaaataga
    12361 aacaataata caaacaagtt gcgtaataac tgcaccgata tttcctgctg ttgccagata
    12421 agcattgacg atcggcggca ttggccaagg gaccattaca actgctttcg ccgcaaaccc
    12481 taaagcggtt gcaaaataac caatcgttcc tgtgataaga ggcgttaaga taaacggaat
    12541 agctaaaatt ggattcagca tgatcggcat accaaaaata actggttcat taatgttgaa
    12601 gatcccagga gcaagggata acttggtgat ttgtttcata tcctcccgtt ttccaactaa
    12661 caatactgca atcagtaaac cgatcgtgac tccagaccca cccatactca tatacatatc
    12721 ccaaaatggc atagtaataa tgttcagtac ttcttttcca gcttcaaaag cttccgtatt
    12781 tacagcaatt gccgctaaaa gcaacggttc ccgtatcggc ttcaccattt gatttccatg
    12841 gataccaatc acccaaaaga cttgcgcaat aaacatcaat agcaaaatac ccggtaaccc
    12901 ttgaacgaca ccttctaatg ggcgttgtac gacattgtaa atgatatcat aaaggtacat
    12961 tcctgtaagt tctttgatga taaatcccgc agccgcgata cccgatacag tcagaatcgt
    13021 cgggaataaa gcagaaaaac tagcagaaac attcgttggc acggtatcag gcattctcag
    13081 ctgtagtttc ttctgtttcc tcaaccagca ataaagttca atagaaagga tggagaccaa
    13141 cattcccaaa aataaccctt tcgtgtctgt atattgttta gccaatacgt tttctactat
    13201 aacagtctga ttttcattca ctaattcata aacagttgga ttaacagata aataagacat
    13261 cactgcgatg ataccaggga atacaccatc cactttattc agcttggcta attcgatccc
    13321 tattagaaaa acagcataga tggtcaagaa acttagtgtg acatagctga tggcagatgc
    13381 gataggcttt aattcttcta aaaaacgcaa gtaacttatc tgtgctaagc cattttccga
    13441 gtcaaagacc attgctgaaa acaatgtgcc aaaagcaccc gtaataatta ccggaatcaa
    13501 tgcagcaaat gcgtttttta tcaccatgat ataccttaaa ttattgattc tcgttgccac
    13561 gttccctaaa actttggcta atttatccat aaaactcatt ccagatcccc tcattcctgc
    13621 ttcttctcct tgacgtcatc tctttttgtc tattagtcag cgcttacatt ttggtgaaca
    13681 gaaactattt actcctcttt tttaccaaat ataaaacaaa aaatcatctg atgtatttat
    13741 cataaaatac atcagatgaa ctgtcaatta gtttcttttt ctcctattat tttctgtaat
    13801 tctctccgat ttattgccat atggacagtc attgcgtcaa acgcagcaag tacgttccgc
    13861 ctttcgatgg cctgaacgat ctctgtatga atatcgatcg tctcgatttt cagatgctgg
    13921 atatcataat ttttattaaa caaagcaatc gattcattaa tgattgggat aatatgcagc
    13981 aaggctatgt ttccgctagc ttctgcaatc atcgtatgaa aatcgatgtc taattgaaca
    14041 tgttcttgtg tgccttctcg aaaagaagtt tcaatctttt gcgttaattt tttcatttgg
    14101 acgatttgat tcttcgttgc atattccgct gccaaacctg ccatcttagg ctccaataaa
    14161 tatctcagtt caaataagtc tcgtatcatc cgatcctgat cttcaatcaa agaaaaaccg
    14221 agtgggtcat tggcaatccc tcgcttatca ctgacaaatg tccccgctcc ttgccgaact
    14281 tcaaggatat tcctggaagc tagagcccgc acagcttctc gcaccgtgct tcgccccacc
    14341 tctaaataat cggacaattc atattcattc ggcagtttat ctcctacttg caactgcatt
    14401 tcctttaaat atctaaggat cttgtcagta gttacttcta ctagggtttt attttcttcc
    14461 aaaccacata cctccttttc atctgatgta ttttttcgta attattataa cacgtttgaa
    14521 tcatctgatg attttttgta taaaaaatcg attaatccgt tcatagacat acaaacgaag
    14581 aagatattta ccataaaaaa gactaggata aaattcactc ctagccttcg atcattttta
    14641 ttttgatcga caaaaaatat gatgttcaat aacagacgat cttcattcga ttcttgatgt
    14701 catcttttgt tttttttaat atatggataa aaagtttgat tacatcgttt ctattctaga
    14761 atttggtcga ttctcaattc ttcttctggt gagaaatcta aattatccat cattcgaaca
    14821 ctttcttgta actgacttaa ccgacttgct ccgatcagta cacttgtaac agatttttgt
    14881 cgtaaattcc atgcaagggc tatttgcgct aatgattgtc ctcgtgatac ggcgattgtt
    14941 tgcagtgctt tgattttttc cagagttgat ccaacttgtt cttctgaaag gaatggtatt
    15001 tccttacgat gtgctctaga atcttcagga ataccatgta gataacgatt tgtcagcaac
    15061 ccttgagcaa gcggactgaa cgtgattgcc cctagccctt cttcttctaa tactggagat
    15121 agatcgtctt ctagtagtgc acgagaaaac atattgtagc gcatctgatg aataatgaac
    15181 ggtgcttcct ttctttttaa aatttcagtc atttttttgt atcttctcca ttatagttgg
    15241 atataccaat atataatgct tttccttgtc ttacaagttg catcaacgct tctgctgttt
    15301 cttccaaagg tgtatcaggg tctgggcgat gatgatagaa gatgtcaaca taatctagcc
    15361 ccattctttg gaaactttgg tcacaacttg atatgatgga tttacgagag ccccattccc
    15421 catatggccc ttcccacata tgataacctg ctttgctaga aataatcagt tcatcacggt
    15481 aggcttgaaa atcttctcta aaaatacgcc caaagttttt ctctgcagct ccagcagggc
    15541 ctccataatt attcgcaagg tcgaaatggg taattcccat gtcgaatgcg cctcttaaaa
    15601 tctctctttg attatggata ggatcataat caccaaaatt ttgccataat ccgagaggag
    15661 agataaaatc ggtaatttta aacctgaatg accggattta cgatattcca ttttttcata
    15721 acgtgcacta tctgcaatat acaatttttc tcctcctcat caaatctttt taaaacgctt
    15781 tcttgttttc tatttttagt ttactacatt ttaaagaaaa ggagttaatc aaaatgattt
    15841 tttcgtatat ttttttgcca tttgtttttt actcgttgat agatcagaaa ttgattacgt
    15901 gcttgctgga tttttttata gcgtttcggt tgttttttgt aaaattgctg atgatagttt
    15961 tctgctggcc aaaacgtacc ggctggttcg atttttgtga cgattggttg gtggaaagtt
    16021 cctgaactgt ctagtttctg ttttgattgt tccgctaatt ctttttgtcg ttcgtcttga
    16081 taaaaaatca ctggacgata ttgcttccct ctatcttgaa attgtccaaa tgtatctgtg
    16141 ggatcagtaa tttgccaata gattgtcagc aactcgctat aacttatttc tcttgtgtca
    16201 taaatgatct ccacagcttc cacatgacct gtgtaaccac cacttacttg atcataattc
    16261 ggtttttcaa catgtccgcc cgtgtatcct gacaaaacag ataggatccc ttttttcgat
    16321 tcaaacggct cgaccataca ccagaaacat ccccctgcaa atactgcacg ttcttgatag
    16381 tcagcatctt gcatggcatg cttggaaaag tcatattttt gctccttatc aaatccttcc
    16441 gtaatcaata aataaaagtc cattacatca ggcgtcagat tcattcggat agctaatgga
    16501 cgtagtgtta cttctagttt tgataactgt tctttaacgg atatattttc tcttgtgtca
    16561 ttctttgtct gaatcaatac ttttcgttcc caatctcgtg tattcggatt caaaatcaga
    16621 ttataaagtg tttgaatgaa tatttgttcc tcatccatag attctcctcc tttccgaaga
    16681 agacaagcta gtgactttag ctgtaattta tcataaagtg aggaaataat cgattgaatc
    16741 gtatttattc aaagaagata agcagcttca gatgatataa gatgatcttt atcttaaaaa
    16801 gcatactcta tggtttggtt taactaaaaa acgacctctg aaaaaaggga tgttctccaa
    16861 ttctcagaag tcgagtaaag atgattcttt tttatgagcg ataataaact tcatccaaaa
    16921 acagaccttg tgcagggacg gtttctcctg catgttgccg cactttgctt tcaaatattt
    16981 catcgattgt ttctatcggc atggcacctg tgccgatttc tagtaatgtc cccatgataa
    17041 tccgcaccat tttatataag aatccgtctc cgacaaaagt aaaatgaagc atttctccct
    17101 ttcgttcgat agataattca tcaatcgtac gcactgtgga tttttttgat tttttcaatg
    17161 cagaaaaacc aatgaaatca tgtgtaccca ctaatttttc gcaagctgca ttcagcttgt
    17221 ccatatccaa ctcttgaggg aaataaaagc tgtggtttcg ctcaaatgct gaaggaatca
    17281 cgttgttcca aacataatag ctgtattttt tgcccaccgc attatatctt gaatggaagc
    17341 gctcaggcat ttcttcgatt cttttgatga caatatcccg cggaaggtaa cgattcataa
    17401 agtcgatcat ttctgccagt ccaatttctg tgtttgtttt aaaatttgct acttgtcctc
    17461 gcgcatgggt gccagcatct gttcttcctg atccaataat ttctatctct tcatttgtca
    17521 tctgatgcaa tactttttcg atttttcctt gaatggtttt atcgtcatct ccaagtcttt
    17581 gccatcctga atatcttttt ccgtcatatt cgattgtcaa cttgatgttt ctcatatttt
    17641 agtggctcct ctgtcttcca tttggtcttc tctctacctt tttaagattg tagcacaaaa
    17701 tatagctcct tgcttctcta agacagaagc tatacaagaa aactgtggaa atatatattt
    17761 cagaaaaaca aaaaacagcc accggatgaa gtatccgctg actgttcaat ttgacggctc
    17821 aagttttact gtttgagatg caagatactc aaccaggcaa tgggcacata attaaagaaa
    17881 aaactgattc tttggcaaaa acctatttta ttcagtaatg gccaagaatt tatagaagga
    17941 attcttgcca gtccataaat cgccgcaaaa agcaaactga tcacagacag tccaaggtat
    18001 aagtggctta cgtccatttg cccatttttt cgatagatca agaaaagaag aactggaaac
    18061 aataaaaaac cactgtaacc taaacctgat ccgatattat ggacccatgt cgagacattc
    18121 cacgaagatt catgggtatt gatactgaac aaacctgtaa agatacaatc acctatacca
    18181 tagaacgcga tggctgctgt aactagggta gctaacacac gagatgtact tacaaatgca
    18241 gcatacaatg caggcaatga caggatgaaa aagatccctg aaaccacaga ccaaataaga
    18301 aacgcttttc ttacaggact ggaaacctct ccaaatacac tgatcacgct cttcatttga
    18361 tctaattcag gataatacaa tcctaatacg tacggagtca aaaaatcact cagcacgcct
    18421 aataataaaa agaaaaaacc aaatttacgt aaaaaatcca tgatacgcct ccaataacaa
    18481 ttacctatgc ttttaattgt tattataaac gactttatct tgatttaaca gaaacctcta
    18541 tttacacgaa catctatata actcattaaa aactcgaatc attttaaaaa tactaaatat
    18601 ctaacgttca acgttcactt aatccatcta aacaatcttt caatttgatt ttttccccac
    18661 ttcttttacg cgcgcctagc tctcctattg cagtaaacaa cagatcactt gacgaattta
    18721 aggcagtttc cattgaatcc tggataacac cgataataaa tccaatacca acgatttgca
    18781 tcgcgacatc attagagata ccaaacaaac tacatgctaa tggaatcaat aacagtgaac
    18841 cgcccgcaac acctgaagct ccacaagcag ctaaagcaga caaaatacat aaaaggactt
    18901 tcaaaacaaa tggtgcttca atccctaaag aatgtacagc agtcaacgtc atcaaggaaa
    18961 tggtaatcgc ggcaccgccc atattgatcg tagcacctaa cgggatcgat atggaataag
    19021 actcttttgt caatttcaat ctttcagcca acatcatgtt tatcgggata tttgcggcag
    19081 aacttcgggt aaagaaagcg ggaagtgcgc tttctttcaa acaaaagaaa atcaatggat
    19141 agggattttc tttaataaac aaaaacgtga ggaatgggta cacaactaat gcgacaaaca
    19201 gcatcgtacc gatcaaaaca agtaaaagct gcagatactc tgccaatcca gcgattccag
    19261 tcgtagcaat tgattgataa accaatccta aaatccctat cggagcaaat gcaataatca
    19321 cttgtacgac ttgtgacaac gctatagata tctgatccac caactctttt gtcggttctg
    19381 aacgtgctcg aaaagctagt cccaacaata cagcccagaa taaaacgcca aggtaattcg
    19441 catcaataag agattgaaca ggattttgtg tgacattcgt caacatagta gataaaacac
    19501 tttccaaact ttgcggtgct ttttcagata ctgtttcttg taaagtaata ggaacagtaa
    19561 aaattgaact tacaatgact gctacaagtg cagaaagcaa tgttcccact aaatataaga
    19621 tcaaaatagg cttcacgaat gtcttattcc caattttatg cttggcaatt gacgccatcg
    19681 tcaagaaaaa aaccagaata ggtgcgattg ccttcaagca actgacaaac aacgtcccca
    19741 atattgaaat aaatgtccac gtggggaaaa agataccaaa caatattccg actaaaatac
    19801 caacaacaat acgttgaact aacgacatat ccaaaaactt ctctaacaaa tgagcaccct
    19861 ttcacaattt taacaatcat tgtatcattt tatctaaaga aactaaaggt gcaattttct
    19921 aaaaattcta ataatacaat tggcaattca tgctcttgca acattcaatt ttagtattgg
    19981 agggtttatt caatctctaa agaagtcgag agaaaactat ttatcgttat tattatagtt
    20041 atccaagtaa aacgtaacta agatgaagga cgaaactaga aatttcatcc ttcatcttaa
    20101 ttcttagaca tagcaatcaa ttaatatttt ccactgagtc tcttctttct ctcactctca
    20161 ctggtttact tacccataaa cgatttgatt aaagccattt ttcaattcat tattcgctgt
    20221 ctcgttaaag taaagataat tatcgggatt cccctgattt tgttgtgtca ccaatacttt
    20281 tggctgattt tgctgaaacc cgaatagata gacgtgcttt ttcagatatg gttctgtctc
    20341 tgcatcggaa tagacggctg tgatttgata gtctgcttga cctgtcccac tttctgacca
    20401 ttctgcagaa acaggcactc caccaatagc catcttccac tccccgttca aaataacttg
    20461 agggacttta agaccatata agtccacact catttgattc gtatagcttt tgtattgttg
    20521 tcccattgtt tggccccatg tagccataaa tgcctctaat tgtgcggatt tgtctgcatt
    20581 ccacagtgtt tgttcgactt gttcgctgct ttctgaagat gaagcctcta cagaagaact
    20641 tgaagtagat gtttgagttg tttcagtcgt tttggaagac tctgacgaag tagaggtatc
    20701 tgctgtttcc gtacttgctg cagttggctt gctctctgtg ctagttgttg tagtagttgc
    20761 aattgttgct ttcgctgttt cttttgttga ttcttttttc gattcattcc cgttggtaca
    20821 accagctaac aaaaaagcta gaccaattgt tactaaaatc ctttttttaa attaaaaaac
    20881 tcctttcgat tactcccact tctttattct atcaaataag caatgtgatt ttattgattt
    20941 tttgtatttt ctcatccatc ttttaaacct tttaaaaact aagaagcacc cgctgatgtt
    21001 gtctgtaata catcagcggg tgcttctttt attttaatct tcgcgatttt ccaatttacc
    21061 tcacgcttta tatttgtatt tgaagaaaca tagactttta gtcatcatcg tcttcctcat
    21121 ccaaatcttg tcggacagtt tttccttgga gtctttgtac ttggtagatg atttctttat
    21181 tgaaacttaa aagttcaaca agcaattgtt tcaagccata tttttcttct ttttcagcta
    21241 atttgattgc ccgtgtgata aagacatttt ggaaatcaaa atcttttgca aagttttcca
    21301 acattgttga ggctggtaaa tatttgtttt gaccatgttc gtaaattttt ccataacgca
    21361 tgacttcttc taaagtagac ggaacgattt cattttcaat cactaactca tgagagattt
    21421 tattgaacca tctcgcttct tgatcagcat attctgaaaa aagggtactt aattcttgcg
    21481 aagatgtacc caaaacatac aattgtgctt ggatcaattt catttcttct aatttaaaat
    21541 ttgccaatac atgccccacc atggcgccag cagttggttt atgatgatcg atatctgctt
    21601 gttttgtttc ttgagcaaat ttttcttcca ctatattcac tgatttacgc ctcttttact
    21661 tttgttgatt ggacttcata acctaatttt tccacaactg cagctaattg ttcagggtgg
    21721 acttcatctg gatcaaagtt tgctttgatt ttgctcgcat taaacaaaac tttcgtattg
    21781 cttaccccag gctgttgaga aaccgcatgt tctatttttt gcatacagct tggacaagct
    21841 agtgtatcta attgcataat catttttttc atcgtagttc ttccttcctt tttcttgata
    21901 gtcttattct agattacagc ttccataaaa aaattgattc ttatcaagtt ttacgatttt
    21961 tcttctttgc tttcgtgtcc aaaatacaat aaacgcatcg cgttaaagat aacgatcaag
    22021 atactagctt cgtgaacgaa catcccacta gccatgtaaa taaacccggc aaataagccg
    22081 atgagtaaaa ataagacgac accaatggca atcactacat tttcacgggt attcaaaaca
    22141 gttttcttag ccaaacggta agcatgaacc aacgatccaa aactagattg catcaagaca
    22201 acgtcactcg tttcgatagc gacatccgtt cctgatccca tagcaatccc gatatcagcc
    22261 gcagccaaag agggagaatc attgattcca tctccaatga aagcaacgtg caatccttgt
    22321 tcttggtatt ttttcacaaa ttgaaccttt tcatctggca ataattcagc atggacttca
    22381 tcaatgccta acatgtcagc tacataatca gcagtcatct gattatcacc tgtcagcatc
    22441 actaaatgtt ttgctcctgc ttgtttcaac atagctaatt gttcagcgac ttctggtcga
    22501 atcacatctg acacaccaat gatttgagtg atttttttgt cgattgctac aataatgact
    22561 gagctgcctc tttgttgtaa ttgatgtaaa tcttgtactt gctttggtgt gagagaaagt
    22621 ttgtgagcgg caatcaattt ggtgttgccc gcacaaactg tatgaccatc aatctcagct
    22681 gtgattcctt gtcccttgat cgtctgatta tctttgactg ctaattgttg aaaatcaatg
    22741 tctttctcct gagcataatg gatcacggcg cgccccagag gatgatcgga taacgtttct
    22801 aatcgagcca ctaaagctaa gctgtcccct tcatcctctg tatagttctt gatagtggat
    22861 acagcagtag ttcctttggt caatgtaccg gttttatcaa agacaaaagt atcgattttg
    22921 gaaaaagtat ccattgcttc accgcctttg actaagatgc cccgtttcgc tccattaccg
    22981 attcctgcta cattcgaaac aggcgcacca atgactaaag cgccaggaca accaagaacc
    23041 aaaacagtga tggctaaacg aaaatcacga ctgatcagac caacaagcaa cgcaataagt
    23101 aaaacggttg gagtataata ctgagaaaat tgatcaatga atttttccgc atgtgatttg
    23161 gtatcttgtg cttcttcgac taattctata attttggcaa aggtcgtatc atctccgacc
    23221 ttagttgctt cgatcgtcac gtagccatct gctaaaatcg ttccagaaaa tacgttatct
    23281 ccactgattt tgacgacttg tcgtgattca cccgtcactg cggcttcatc cgcataccct
    23341 ttcccgtcaa tgactcgtcc gtccacagga atagctccac cagtttttac taagacgata
    23401 tcgccttctt ccacgtcatc gatttccact tcttcggtcg ttccatcttc ttggacaacg
    23461 ctggcagtcg atggggccat ctcggtcaaa gccttgattg attcccgcgt tttggtcaat
    23521 gttttttgtt ccagataact accaaacaaa aacaagaatg taacgatagc tgactccttg
    23581 tattctccga tcataaaggc accaagcaca gcaatagtaa cgagtaaatc aattgagata
    23641 actttgactt ttactgcctg atacgcatgg attataatag gtatgaccgc aataatagaa
    23701 gctatggcta gagcaatgtt atagaacaag acaaatccag taaatttccc gataaaacca
    23761 aaaataatca acacagctga taaggcggtg atatgatttc gatgctcttg gatccacttt
    23821 tgtaatttca tctttctccc tcttttcctt ttcattctta cgagactaag tatagatact
    23881 tatccatcat aaaaaattga ccactatcaa gtttattcaa aaaggcggtt ttcttttggt
    23941 atactgaatt cctacagtca ttaaacgatc atatagaaaa aggaagcgcc gaaacgcttc
    24001 cttaggtagt tctatttttt tattcaaaga taagatgctt tgtcatctta cgactgaaga
    24061 acaacaatca aaaaagggca gcagccactc attcacaaga aatatcgttt tttgatatgg
    24121 gagttgaagc agtggacaaa tatctctact tattagctgg gaataagatc caaaaaagct
    24181 taatggattt tatccaagaa ttggaatgta ctttccacaa aaaattcact cattccattc
    24241 ttttaaaact tttgattcat acagcgtgtc taattgagcg tacattgata aacggtcatg
    24301 aacttaaaat tatatcagaa gatgacacaa gaccttctca tgaaacaatt tttcatgtaa
    24361 aaaaggcctt caaaaatatt gaaacagaat ttgggatcac tgtttcttat gatgaatgtt
    24421 tctttatcta tgatattatc gcatctaaat aatctttttt tatgtaaacg agtattttgg
    24481 gagcgtcaat aattttgtgt aaataaattg tcctcctgca aaataattag ttactcagta
    24541 aacattgaaa ctaatgtatc ggttac
//
LOCUS       DAPBCF010000038        24271 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.038, whole genome shotgun sequence.
ACCESSION   DAPBCF010000038 DAPBCF010000000
VERSION     DAPBCF010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.038"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..572
                     /locus_tag="RD508_001914"
     CDS             <1..572
                     /locus_tag="RD508_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7736468.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="RD508_001915"
     CDS             576..1217
                     /locus_tag="RD508_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7736469.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="RD508_001916"
     CDS             1214..2131
                     /locus_tag="RD508_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7736470.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="RD508_001917"
     CDS             2128..2799
                     /locus_tag="RD508_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7736471.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="RD508_001918"
     CDS             complement(3340..3828)
                     /locus_tag="RD508_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HDT7736472.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="RD508_001919"
     CDS             complement(4029..4295)
                     /locus_tag="RD508_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HDT7736473.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="RD508_001920"
     CDS             complement(4295..4558)
                     /locus_tag="RD508_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDT7736474.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5034..5219
                     /locus_tag="RD508_001921"
     CDS             5034..5219
                     /locus_tag="RD508_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7736475.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5361..7184)
                     /locus_tag="RD508_001922"
     CDS             complement(5361..7184)
                     /locus_tag="RD508_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HDT7736476.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7782..10487)
                     /locus_tag="RD508_001923"
     CDS             complement(7782..10487)
                     /locus_tag="RD508_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDT7736477.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10793..11740)
                     /locus_tag="RD508_001924"
     CDS             complement(10793..11740)
                     /locus_tag="RD508_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HDT7736478.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11930..12199
                     /gene="rpsN"
                     /locus_tag="RD508_001925"
     CDS             11930..12199
                     /gene="rpsN"
                     /locus_tag="RD508_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDT7736479.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12375..12737)
                     /locus_tag="RD508_001926"
     CDS             complement(12375..12737)
                     /locus_tag="RD508_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDT7736480.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12748..13869)
                     /locus_tag="RD508_001927"
     CDS             complement(12748..13869)
                     /locus_tag="RD508_001927"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDT7736481.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13885..14235)
                     /locus_tag="RD508_001928"
     CDS             complement(13885..14235)
                     /locus_tag="RD508_001928"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDT7736482.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14365..15876)
                     /locus_tag="RD508_001929"
     CDS             complement(14365..15876)
                     /locus_tag="RD508_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDT7736483.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16198..17550)
                     /locus_tag="RD508_001930"
     CDS             complement(16198..17550)
                     /locus_tag="RD508_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDT7736484.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17703..18779)
                     /locus_tag="RD508_001931"
     CDS             complement(17703..18779)
                     /locus_tag="RD508_001931"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDT7736485.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18975..20720
                     /locus_tag="RD508_001932"
     CDS             18975..20720
                     /locus_tag="RD508_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HDT7736486.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21000..21437)
                     /locus_tag="RD508_001933"
     CDS             complement(21000..21437)
                     /locus_tag="RD508_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HDT7736487.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21421..22794)
                     /locus_tag="RD508_001934"
     CDS             complement(21421..22794)
                     /locus_tag="RD508_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736488.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23116..23604)
                     /locus_tag="RD508_001935"
     CDS             complement(23116..23604)
                     /locus_tag="RD508_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7736489.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23626..24228)
                     /locus_tag="RD508_001936"
     CDS             complement(23626..24228)
                     /locus_tag="RD508_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDT7736490.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6960 a         5165 c         4486 g         7660 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgatttgatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag ttctatcctt
     7441 tttgatatct taacttttgg aagagagatg taaggctgct ttctacccat cattcttact
     7501 actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa agcttgcatc
     7561 tgcggtaata agctcaacca aattaaaaac ataagaagct gtttttattt ggtcgttctt
     7621 attacttgat gcagagcagc ttttttacaa cctcttggta cacggtgttc aatcagctga
     7681 ccctcggtat tagctcaaaa aaacggcaaa atatgaggaa ctatttttcc atttttttct
     7741 ctaatactca ggtcaaaaca ctgatttcac aacctctttt tttaatgaaa aatatggctc
     7801 tcatgcgccg cttctttgaa tttcgtcatt ttttcttcga tgaacggata gattgccgtt
     7861 cctacgattc caaagacaac aaacaaaccg atcatgatcc agattgcttt cgtagcattt
     7921 ggccaataaa ttcctcctgc agattcccgt aacaagttta ccgcatgagt aaatggcaag
     7981 aacggattga tcatttggaa gaatttccct gagacttgga tcggatagtt cccgcctccg
     8041 ccagagatcg acagtactaa gatgataata gcgatccctt taccgacatt atcgaataat
     8101 gcagccaaga catagacgat catcatgaac gctaaggcga tcaagacagc aaatgacacg
     8161 ctgtagaccg gattttggac atctactcct agtaagaaaa tattccctaa tgtaacgatc
     8221 aagctttgcg caatcgccat tgtcaaaaat gtcagcatac gagcaacgaa ttgttctcgt
     8281 ttcgtaaaat tgtttcggtc tttctttcct aaatagtatt ctgtcgtagc aacacttgaa
     8341 agaagaacag cgccgaccca cagacatagt gcagtataaa acggggtgct agctgaaccg
     8401 ttatttgcga ttggataaag cgcattggtt tgtagctcaa caggttgtgt aaagaagtca
     8461 ctttcttttg ttgcgtctag tttcaataat ttgatgactt cgcctagatc gacttcttgt
     8521 tcgccttttc ggatcgcgtc tgctgctttt tggataccag ctttgatatt tggccagtca
     8581 ttgttgatca agtccgcagc agcgttcaca gctgtttcga cttctggcat tttttcattt
     8641 actgttgtca atgtaccggt gatttcattt tttagtgctg gccaatcatt ttggataaaa
     8701 tcagcggcca atcctaattt ttgctgaatg atcggtaatt cattgttgta taggtctgcc
     8761 ccttcattga tgccattgac gatggtatcc atatttccat tcagcattgt attggcatca
     8821 tggatttctt gtccaattgc aggcatttct ttttgatatt tttctaaaat tgccactgca
     8881 ttcgttacag ttgctttcgt tgagctgaga agcgaatcaa agtcgatctg gtccgctttg
     8941 ctcagtgcgc cttgtgcagt cccaatcgta tcgatgactt ggtctagtag agaagtgaca
     9001 gtggaactga tttgacctgt attgatacca gcaatgatgc cattgatatt attaacaacg
     9061 gcatcaattt gatctagcaa ttcatcaata gccttcgtgt cttcattttg aacagctgtg
     9121 ttcaaagcag ataggcggtt ttgcagattg cttagcaagg gttttaattg atttagctga
     9181 tcaataattg gctgtaattt cgtatttcca gcacttgttt gcaatttagt caggaactcg
     9241 accagtttat cgattgcatt ttgttgttga gatattccgt caataaagcc gttcaataca
     9301 ttgctgatgt ttttcttttc atcatcagtc agcttaccat cttcaatagc tgttcttaca
     9361 gtatctatta acgaacctgt cgttgttgcc acttgtccaa ttgacttcaa tgtaacatct
     9421 acactgtttg tgatgcttgg tatcgcatct ttcagctgag aggcacctga ttttgtttgg
     9481 tttgctagat cacttgcctg attttctaaa tttttcacat ctggcaagat atcttgtact
     9541 tgttggatga tcgtcaagcc ttgttttgct tcatcgattc cttggttcat tgtctcttgg
     9601 atcgaagcaa aatcgccgtc gatctctgct agttgcttac cggcattttg gatctctggg
     9661 attttttctt gcaaatcaag gatgattttt gcttgatctt tcaactcagg cattttgtca
     9721 ttcaatgcaa cgactttttc acccatctca tctactttag ggatgtaatc cacgaattca
     9781 tttgctttat tcagtttttc cttgatttca ggtagttgac tttgtaattc gaggacttgt
     9841 tttgtgtagc cgtcgatcgt gtccaaattt tcatctgttg ataaaatcat atctttaact
     9901 ttattgatac ttactaggtt cgtatcgatg tcgtaaccta tctcattgaa tactttcaat
     9961 aaagtcgaac tggctgtttt gataaattca tttgtgattt gcgattggat cgaacttgct
    10021 cctttatcgg tgattttcgg tgcaatcgca ttgatttttt catttaccgt atattcgatt
    10081 tttggtttct tgatatcacc actagtaaaa ctcagcagat cttctgagaa atcctttggc
    10141 aagtaaatac ctgcgtaata ctttccggaa cggactccgt cttctaattg ttcttttgaa
    10201 tcaacgaatt gccatcctaa ttgtttattt ttatgaagcg attcgatgac ttgctcccca
    10261 atggccactt ctttaccttg aaactctgct ggcttgtctg cactgtaaac agcaattggc
    10321 agctctccag tatttccata tggatcccat aatgctttga tgttaaacca cgcatatagc
    10381 gaagggatga tcatgatcgc gatgatcaga agtgttgcaa tcgggttttt gaaaatccgt
    10441 ttccagtcaa gcaaatataa tcgaagcgta tttttgattg actgcatagt tctccccctt
    10501 cttctttttt cagctgaatt actttaccat gtatttcata cttttttcaa tcggcttttt
    10561 tcaaaaaagt cgaatttttg gacatatcac ggcaattgtc tcattgtaat ctcttacata
    10621 ttgagaaata attaaggatt acagccttta ctttatcatg aaataaaagg gaaagataat
    10681 tttatgccaa agtttttatc tattatacgt atacgcaaaa aagctaaaac attttttgtc
    10741 tttgccccta caaaaatgtt tcagcttttt tcgtttttta ttcctgtatt tcttattttt
    10801 cgaatgacag gatgattttc ccagcaggag gatgtccttc aactagctga tgtgcttgga
    10861 tgacatgctt aagtgaagca gacagattca ttgaaataaa aacatgaaag gctccttttt
    10921 ggtaggcttt gattatgcca gcaaaggctt ctgcatctag atattccttt cttggaacaa
    10981 acgattcata aaagccttcc tttttttgcc gcaaatctag atctgggagg tcatttaatg
    11041 caacatacct gccgcctggt ttcatgatct ggatgccggt ttctcctttg atacttcctt
    11101 tcgtcgcatc gattacaagg tctgcctgat cagcaaattg cagacctgga tttgttttat
    11161 cataagcagc aaatgctgaa gctcctaatt tttttacctt ttcctcattt ttactggatg
    11221 cactggttaa gattcggatt cccttttcat ggagaagctg gatcagactt gacccgaccg
    11281 cacctgatgc tcctagtatc attacagtat ctgtcggctg gatttccgtc aaatggttga
    11341 ttagattata agccgtaatt cctggcgtga ccattccggc tgcttcttcc caactcattt
    11401 tatctggaat ttttgctact tttgctgatg gcaacacgac ttcttctccg taagtcccgc
    11461 cgactgcatg gacagctact cgatcaccta catgaacagt tgtgacatct gaaccaatct
    11521 ctgtcacaat accagcgcca tcattacctg gtacataagg gaatttcaat gttcgtatct
    11581 ctttcatttc tcctaaacgc aaggcaacat cataaggatt cacactgaat gcttttattt
    11641 ctacacgaac atgtccagaa ccgacttctc tgggatgagc atcgatttct tcaaaaacat
    11701 cttgtgcttc tccgtaaccg ttaattgcaa atcttcgcat ggtcaccatc tccctttttc
    11761 tttaagttta cgtttatgcc tttattttga caaaaaaaat gtcttttcgt tttggcgcat
    11821 gattcaaaac aaaatagttg tcttttttcg cgtaacgtgt taaattattt atctaaaagc
    11881 gtaaagatta cgatttacgc taataaaaaa taattggagg aatttgttga tggctaaaaa
    11941 atcaaagatt gccaaagcaa aaaaacagca agaaacgatt gaacgctatg ctgctttacg
    12001 ccaggaatta aaagcgcaaa aagattacga aggcttgcgt aaacttcctt tagatgctcg
    12061 tccagaacga ttgaaaaatc gtgatttaat cgatggacgc cctcgcggat acatgcgtaa
    12121 attcgggatg tcccgtataa aattccgtga attagcacat aaaggtttga ttccaggagt
    12181 aaaaaaagcc agctggtaat ccaagtctgg ctgtaatgta aaggaggagg gcgcatggac
    12241 cactccttgg atcatcaaaa aagatacgtt cgcttcttct agcagaaatg ctggtactag
    12301 aagcagacgt atcttttttt acgcacagct ggtccttttt tatatgtaaa ggctgcatgg
    12361 ttacttcgct atatttattt agtaacagga gtcagtgctt cgatacccac actaattttc
    12421 aatgctcggt caacttctgc cataatgggt cgatccaaat ggcagacctt ttctttcaat
    12481 cttgatttat cgatcgttct gatctgctcc aacaggataa cggagtctct ttctattcct
    12541 gttccagtag ctttgatccc aatgtgagtc ggaagcttag gtttagccat ttttgccgtt
    12601 atggccgcaa caatgatcgt cgggctaaaa tggttaccta gattattttg aataaccaaa
    12661 actgggcgtg ttccgccttg ctccgatccc acgactggag aaagatcagc aaaataaata
    12721 tctcctcttt ttaccatagg atcctcctta ttcttgatat tctcttggta tccgctgtcc
    12781 taatccgcaa gccacttcat agtggatcgt acctaattga tctgctatat cctgcatagt
    12841 gatttctttg tctgcatttt tgccgataag cgtcactttt gttccgacag gaaattcttg
    12901 aggcaatcgg atcatcagtt gatccataca tacacgccca atcgtttcac agtagttccc
    12961 ttctaccaat agagaaaaac cctgcatctt tcgtggccag ccatctgcat aaccgatcgg
    13021 tatcgttccg atccactctg cttcaggagt gatatatgtt tctccatagc cgattccttc
    13081 acctgctggg agttttttga cttgaatcaa ttcagaaacc agctcaagtg ctggctgcaa
    13141 tggataaact tccggtagtg cgtgcccaga gggattaagt ccgtacattg ctactccata
    13201 acgaatcata ttgccgattg tttcatcatg ccataaagcc gttgcactat tgctgacatg
    13261 tacatatcga ggaagttcgg gaagtttttt cagcacttct ataaagcgtt ctttttgcag
    13321 attccaatat gtatcatctg cctgatctgc tgtagaaaaa tgggtaaata aaccttccca
    13381 ttctaataca cgactttctt tgatgaatgc agctgcctct tttacttctt caggtgtaca
    13441 aaatccgata cgacccatcc cagtgtctgc ttttagatga atcgaaagag gcgtctctag
    13501 cttacttttc tctaaaacag cagctgctgc ttgcaaccat tcccgtgtac ctgcagttac
    13561 tgataaatca tgagcaacag ctacagtcag tgcgtcgtaa ggaaccatat tcaagataag
    13621 gatgggctga gtaaatccag cttctctcaa ctcgactcct tcatctaaat ttgaaacaca
    13681 aaagcccgaa gctccacctg caactgctgc ctcagctgtt tcaatagctc catgaccgta
    13741 tccgttcgct tttactactg caaacaattc ttttccttgc ggaagtcttg caacttcatt
    13801 tgctacattt tcagttatag cttttttatg tatcactgct ttcgttgggc ggtgccaagc
    13861 gacaaccatc gtttttcctt ctttctagtc ttccaaaata atttgtgcaa aagctgtttc
    13921 atttgtatga gtaatactga cccatacatt gccttcatga ggtgaacgcg tcacaacagg
    13981 ctgaccattt tcatttttta aaatctcgac atcttgaaag gtaacttttc cgatcccagt
    14041 tccccaagct ttagagaaag cctctttgca agcgtaacgc ccgcctaaaa attctacttg
    14101 gcgatgaaaa ggcaaggact ggaatagttt catttcatca gaggtcaaga ttcgtgcaat
    14161 gaattttggt ttttcttcga tcagccgagt gatcctagga agttcgactg catcgatccc
    14221 aattcctttt atcatatgct tttctctttt caataaattt agaacactct cattctacca
    14281 aattataacc attttgccac aaataagtcc acaaataaca aaaatgaaag tttctcttaa
    14341 aaaagagaaa ctttcatttt atgtttaatc gttatttgaa cggattacaa atccgcgttt
    14401 tttatcattg tgacgtttac cgccatcttt ttggctgtta ttatttttgc tataaccgcc
    14461 ttttgatttg tttccacgat aattaccgcc gtcacgacga ttacggttgt ttccgccacc
    14521 acgtttgcca tttttattgt atcctttttt ctgcattggc aatgggcgtt ctggtgtgat
    14581 cttcactggc actgcatcag ctggatcttt tgctgtcgtt tttagcaaaa gtgcaactaa
    14641 atcttgtgca gaatattctt ctaataattt atctgctgtt tgcaggtatt tatctagacc
    14701 attttctgca agttttgttt cgatttgttc aactgcagca cctaattgac ctttgaatgc
    14761 ttctttttcg gttggtggac gtaaagtcgt catccgtttt ttcgtcaagt tttcaatcac
    14821 atgcaagtag tccatttcat ttggtgtaac gaaagtcaca gacataccgc cttttccggc
    14881 acggcctgta cgtccgatac ggtgaacgta gctttctgga tcttgaggga tatcatagtt
    14941 gtacacatga gtgacacctg aaatatctaa tccacgtgca gcaacgtctg tcgctacaag
    15001 gatatctaaa tgaccgctct taaatgaacg caatacgctc attcgttttt gttgagacaa
    15061 atcgccatgg attccttctg cacggtaacc gcgtgcttct aatccgcgtg ccaattcgtc
    15121 tacacggcgt tttgtacgtc cgaagacgat tgttaattca ggtgtttgaa catcaaacaa
    15181 gcgagtcatg atatcgaatt tttcgtattc ttttgcgcgg acatagtatt gatcgatcaa
    15241 gtcagctgtc atttctttcg ctttgatctt cacatgatgt ggatttttca tgaatttaac
    15301 gccaatattc ttgatagctg gcggcatcgt tgctgagaaa agtaatgttt gtctttgatc
    15361 aggaacttgt gaaatgattt tttcgatatc ttccaagaag cccatattca acatttcatc
    15421 tgcttcatcc aaaactaatg tttgaacggt tccaagtttc aatgtgtggc ggttaatgtg
    15481 gtcaagcata cgtcctggtg tacccacaac gatatgtgga cgatctttca agccacggat
    15541 ctgacggcca atatctgctc cgccgtaaac ggcttgtaca cgtacttttt tgtcgcgccc
    15601 taaacgatat aattcttctt gtgtttggat agctaattca cgtgttggtg cgataactaa
    15661 accttgtaat tcgtgacgat ctggatcgat tttttctaac attggtaatc caaatgcagc
    15721 tgttttccct gtacctgtct gtgcttgtcc aataacgtct tttccagcta atgctagtgg
    15781 aatcgtttct gcttggatag gcgttgcttc ttcaaaacca gcgcgttcga ctgatttcaa
    15841 caattctggt gataattcta gttctttaaa tttcaaatga atcctcctat atggttgtta
    15901 actgaggatg tagctttttt gctaccccgt cgatttgttc ggtcaaagtg tattgtttct
    15961 ttttgacagt ggccacgcac gtttttatcc attcttagcc cctgtggcac caccgaaaaa
    16021 tcactttgcg aagtttaggc attagaaaag ccaaacgggt cgcgttcagc tttatcatta
    16081 ttatgacatc tggcttcaac aagttgtttc tatggcaaaa ccagtccaat ttctcttcat
    16141 ctttcggcaa taggttattc taacatagtt tttcgttttc tgcaagttta cagattttta
    16201 tttcatttgc tgaagttgtt ctaccacttc aaataagccc atgctgttgc tgccttttag
    16261 cataatacta tctgttgctt caagattttg tttgatagca tcaatcaatt tattcttttc
    16321 tttttcaaaa tagaacacag gtagttgggg gtatttttgg ttcaattctt cttttagtgc
    16381 atgcatttgt tccccataaa ggaaaatcat ggcgaatttc tcaggatcga tatgttcact
    16441 catttgcgca tgcatattta aagactcttt ccctaattcc agcatatctg ctaacacagc
    16501 gattctgcgt ccttttgttg gcagattttt aaaagtatct aataccagtc ccatggctgt
    16561 tggatttgca ttgtagacat cgctcaaaat agctgcacca tttcctgccg ttagccattc
    16621 ggttctgttt tgagtgatag aaacatgggc gagcccttgg cgtatctcag gtatggacag
    16681 tccaaagaag cgcccgatcg tatacgcaat caaagcattc gttacattat aacttccagg
    16741 cagcgggatc gtaaatgttt ctccttctac tacaaaatcg gtttgtgctt ttccttttgc
    16801 tgtcacttcc gcatgaacat cgccatttcc aataccgaat gttgtgactg tttgtactaa
    16861 tgttgccgtt aaaggtgtca gcaacggttc atctgcgggc acaacgagta atccgtctga
    16921 tacaagtccg tcagtgattt ccattttggc tttagcgatt ccttctcgcg acccaagatt
    16981 ttctatgtgt gcttcaccga tcattgtgat tgctgcagct tttggttgag ccataagtga
    17041 aagttccgtg atttcattgg cgtgatccat gcccatttcc aaaacgatct tttctgtatc
    17101 ttggggcatg tgcaaaatcg tgtaaggaag accaatatta ttgttgtaat ttccttgcgt
    17161 cttatatgtt ttgtattttt cagacaagac agacgcggtt agatctttcg tggtggtttt
    17221 accattgctt cctgtaattg caacgacttc tgcgcctact ttttccaagt aataggttgc
    17281 caattgctgc atggctttca aaggatctgc tacaggaata actggaaaat tttttggagc
    17341 ttgttcaaca ggcaagctcc aaaatgaagc agatgctccg tttgtgatcg cttgctggat
    17401 aaattcatgt ccatctcgcg taccagcaag aggaacgaat aaacttcctt cggttatctt
    17461 ccggctgtca aattcgacat tggtaatctt tgtcagtgca gagcattcgc tgcccacggc
    17521 ttgtgcaatt tcttgtattg ttagattcat tgagatctct cctaaaaaag gttgtgaaaa
    17581 aagcgtttgg cctaaacggc gggttcgcat gactctcact tccaagtaaa tttctctatt
    17641 cgtatttaga agctagaatg aacgcggtta cgcaatcact ccagcctctt ctttatttct
    17701 ctttattcat ttttttcaaa aaaagattga cgctgatggt atcgattcat tcctaactgg
    17761 atcagttctt caatcaaatc accgtatttc aagcccatat tttcccataa gagtgggtac
    17821 atactgaact ccgtaaatcc tggcatagag tttaattcat tcaggaataa ttcattttta
    17881 tttgtcaaaa agaaatcgca ccggctcaat ccgcttccac ctaacatcgt gtaagctaac
    17941 ttcgcgtact cttgcgcttt ttgataaact tcttctggca cttcggctgg aatctgcatt
    18001 tcgattttat tattgatata ttttgcttca taatcataga atgctacgtc ttttacgact
    18061 tcaccaggca aagtcgtccg aacgtcttca tttcctaata cagcaacttc gatttcgcgc
    18121 gcttcaattc cttgttcaac gattgctcga gaatcatact gataggctgt tgctaaagca
    18181 ttttgcagct cttctcggtt ttctgctttt gtaatgccga cactagaacc catattcgcc
    18241 ggtttgacaa acatcggata aagcaaagaa ccttcacatt gatcaaatac ttttttagga
    18301 ttttctttcc attgattctt aagtactggt acataaggaa cttgcggcac accagcagct
    18361 tgtaaaatat acttggtcat gattttatcc atggcacatg cactggtcaa tacgcctgcg
    18421 ccgacataag gcatattcaa tgtctctaag aagccttgga tcgttccatc ttccccgttt
    18481 ggcccatgta aaactggaaa aacgatggct ccttcttctt tgatttcgcc cggattgatc
    18541 acttttcctg taaagccttc ctctgtctgt ccacttgggt cccatgaaag atgcaagaca
    18601 tctttgctgg caggtttttc tgttagtaat ggacctttga cccattgtcc ttcttttgta
    18661 ataaatacga gttgaacttg gtaataatta taataaatgg catttaaaac tgaaaatgcg
    18721 gaaagaatgg acacttcatg ctctgcgctg cgtccgccat atagtaaagt aatcttcaaa
    18781 agattgtcct cctgtattct aaatcgttca gtgatttact ctcatatttt agcacaaaac
    18841 aaaaataaac gaataactta tttataaaaa aacgagccag cttctaaaag aacgagcgtc
    18901 atttattttt tgtcagctag attatttgtc ccgtttttta taaaaagtta tgataaagaa
    18961 aaggagggat gatgatggcg caaacaaatc cacgcagccg cttggcagaa atcattcgag
    19021 tgttcatcaa ttacaatgta gtgccaaact ttgtacagca aaaaaatccc gaacaggtaa
    19081 aaaaagcctt tgaagaacta ggccccacct tcatcaagat aggacagatg ctttctgttc
    19141 gagaagattt gctttcttct gccttcactc aaacattcaa aacattacaa gatagtgtac
    19201 ctagcgacac attttcaacg gtcaaaaaga cgatcgaaac agaactttct ctttcattat
    19261 cagatatatt cgatgatttt tcaaaatcgc cttttgcctc tgcttctatg gggcaggctc
    19321 atcgtgccaa gctgaagaac ggtgacgcgg tagtcgttaa gatccaacac cctaacatcg
    19381 ccgaagagat ccgacttgat cttcaactat ttgaacgagc gatccctttg atcaaataca
    19441 ttcctgaaac tagcgtagtt gatctaaaag gggtactcca agaagtaaaa cgttccttga
    19501 tcaatgaaat ggacttctta aaagaaagtc aaaatggcga acaattctat caaaagaaca
    19561 atggctggaa agagatccgc agccccaaga tttatgacgc tttttgttcg aaaaaagtga
    19621 tcgtgatgga agaaatgtct ggtaaaaact tgaatcattt aatgaacgcc gaaaacaaaa
    19681 ctgaaacttt tatcactgga attcaaaaca agcagctgaa acaagaagtt gcaaagcttt
    19741 tagttgagaa ctttatgaaa caggtgtttg atgatggttt tttccatgct gatcctcatc
    19801 cagggaatct gctattccat gtactaacaa aagaagaaca gacacaagct agccgaaaaa
    19861 ctgaaacagt ccatgaaaaa gagttcggtt cctttgcttt tcgagcctcc acttctgcag
    19921 aagaccctgt tgcgccatat accatcaact acatcgattt tggtatgatg gggcatcttt
    19981 ctgcaggact taggcaaaaa ctcacacaag ccgttttagc gctgtatacg aaagatgctt
    20041 atcgaatcga aaaagcggtc cttcgacttt gtcagcaaga aggctcgttt gatgaaagtc
    20101 ggttccacca agaactgaca agttttcttg aacagtatta tgattctcct attgatgaaa
    20161 tcaacttgca agaagtattc acacatgtcg tgacgatttg tcatcaaaat aatctgcagt
    20221 tcgatcgtga tatcacgctt ttgctgaaag catttgggac attagaaggg gtgatccgcg
    20281 tcctcgatcc tgaagtttcc ctcatggaag tcgcttcgcc ttttgctcaa cattattttc
    20341 tcactcatct ggatgtagaa gatacattga aacaaagcgg attagactta ttggaaggga
    20401 tgaaggctgc gcctaagatc cctcaacagc tccaccatct attagaaatg tggacttcgg
    20461 gacaaggaaa agtcaatttg gaattgaaaa agcaagacaa attattgagc aggatcgaaa
    20521 gtatgatcaa tcggcttgtt ttcggtatga ttttagctgc attgatcgta gggtcctccc
    20581 tgcttgtcca agcagcacct gtagaaaacg cagaggtcgt ttccttatta gggatattta
    20641 cgtatgctat tgccgcattc gtcattattt ttttggcaat cgatgcattg atccaaatgt
    20701 ataagaagag gaaaaagtag aaaaaggttg tgacagaaag aatcagcttc aagaaataag
    20761 aaggggtttt acataaattg tttctcaaat ttttgtgaaa attcggctta tttttcgaag
    20821 aggctacttc tgaaacaccg agaataaaaa atgtgaaaaa gctgttctgc acccagtaat
    20881 aagaacaatc aaaaagggaa catggaacac atttatcctg tttccctgtt ccctttttga
    20941 tgtattcgag cataaataaa ataccttcgt tacctactat cttctgtact tggtaaacct
    21001 tagtcaattg ccttttttaa cgcttgacga aaagacatat gatctttctc cgtaaagggt
    21061 tttggaccct ttgtccttat gccagctttt cttaactttc cactatgata acgttgttct
    21121 agaagcgtgc cgatattcgc ttcgtcaaat tcttttccag agtgatggaa cactcgcaca
    21181 cccttcggca atacaagtga agctaaacca taatcttgcg tgatcaaaaa gtcattcttc
    21241 ttaaccatac cgacgatttt ataatccgca ctatcagctc cgcggtctac gtagacgatt
    21301 tggacatgat tagcgtattc tttggtcgta taatggtcca cactggtcac gataaccacg
    21361 tcaagaccat aggattctcc taattttatg acatcttctt ttactggaga accatctcca
    21421 tcaatgaata gcctcattct ttttcgcctt cttccataaa tgataaacag ttactaatcc
    21481 gctcagtaaa agaccaacat tgatccattt tgccaagata agcagttgta cactttctat
    21541 cggcactgat tcatggttca gcgtgatcaa taatagatgg attggctctc ccatttcttt
    21601 tgctaaaaca aacaaaagcg tcatcaataa aaactggtgg atcacactcc ctttattttg
    21661 agtagtatac ttgacaacga tccggcgatc cattggaata gctgtatcag tttgataata
    21721 ttccttattt agccagctgc ctgttactac gtgccagaaa ctaagcagaa agacacctat
    21781 cgcaaaacca tttggaatca agaggaccaa taaagaagaa ctcagtccaa gcaattgcat
    21841 agccaatgga gaccatgtta aacgtttcaa aatccatggt ccgactattt ttgctgcaat
    21901 caagcctgct gcataaggca aatacataaa aatcgaaagt ttttctaatc cgtacagtat
    21961 gccaacataa aaactgctaa ataaaaaaag gaaattccct agcattccat ttagaaaagt
    22021 aaacagattt agccagcttg gcaacttcca ttccttcttc tggtgtccta aaacaaacac
    22081 gaacaagatg aacagcagca agaaaccata aatagcaaga tcaaaaagcc tttcatcgaa
    22141 taacaatcgg gcatttctca aaagaaacaa taagccaaag aatatcaaaa ataaaacaag
    22201 ctctcgcgta gctaccagat ttcttttgat gtctttgaaa tccagttcgt aacgcggata
    22261 atgactaacc gtatggtagg ccatgacgta aaaaagtgta taaatagtaa agcttgctgc
    22321 aatctgagtc ggtgcaggca actcaatcgc ttgatacagg agaaatagcc agatagctgc
    22381 aaataagtac tttttcccat ccatattgat aaaaccttgc gtcttttcgt gaaaattgac
    22441 cgtggtatta gcaggtacaa gccatgctgc actcagccct agcaaaacac ttgaaaaata
    22501 aaataaagga aaataaaata cgcctaatat tccaagcaat gaaccagcac caccaatcag
    22561 cagagcgatc atcagcaacg tgtaactatc tagaccaaat cgtagactgt tgactaaaaa
    22621 tagtccagtc atccgaaagg cataaaacag cgtaaatggc aaaatcgtca gccaattatg
    22681 cgagtctgtt agtcccaaaa ataaaagata aggaataaaa ataaccgtgt tacttaagat
    22741 aaagggcgtt gtttgtgtaa aattacgccc aaatcgtttg agtttttcga acatgacaat
    22801 ggctccttaa acagtcttat aactaatctg ctcttcgatt ttagcattaa aggggaaata
    22861 aaccaatttt acagaatata ttcttgtaaa aaaaaataca gaaagaagca taagcttctt
    22921 tctgcatttt tacggtactt gattactcaa gcagacaagc ccttctccac aaaagtcttg
    22981 cccgacaccc ctgcatccgg caggtgataa agatagaaat caattatcct gtgcctccaa
    23041 aatcaattag gagctctgta aaccagagtc cttctcgacc cgtcgcataa atttacttta
    23101 acacagttcc tatgtttatg cgagagcttt tttcatttta taatcgacca tttgaaatcc
    23161 ttgaccgata tctgaaataa gttcttctgt aatctcaaat ccttcatgct tataaacctc
    23221 gattgcttga tgattcccct gattcactcg caaaaagatc tctctttcct ttgtttgcgc
    23281 agcaagttct tcataccagc gaaaaactga agaagtcaat ccttgaccac gtactttatt
    23341 tagcaaatat aatttactta aataaatttt tccatttatc tcttcataag cagtgtaacc
    23401 gacagtcttt tcttcgcttt ttaataaaaa gtaggacaca ccttctgtca gttctttttg
    23461 aatctgtttt tttgactgat aagttttcag catgtaatcc acttgttttt gaccaatgat
    23521 cggcacaaaa acttccggcc atacttcttg tatgactgcc atcagctcat ccagttcatt
    23581 ttctgttact tttatttttt ccatacaccc acgtcctttt ttacattata aatgaccttg
    23641 cgcttgatgg aataaaaaga gcatgatcat gctatacaca cccaccgacc acggtttcaa
    23701 gaaaatcaca atctgcataa attccctaaa agataatttc gtcaaaccag ctactagaca
    23761 gatcaagtcg tctggcgcaa agggaagcag caaggtaaca actagtactt ttttaatatc
    23821 tttcgttttt cttgtcagca attcatcaaa tttctgatac ttttttggcg ataaaataag
    23881 ctggacaaag gctacgccat agtaacggac aagcaaaaat ccgattgctt ccccaatcac
    23941 taggccaata caactatata aaagcccaaa tccattgcca aacatcagca tgcccgctac
    24001 tgaggagatc cctcccggca aaataggaat gatcacttgg atcacttgca acagaacaaa
    24061 tatcatcact gcatacttgc caaattgctg gataaacgct tgcaaagacg tgctcgatcg
    24121 aaaaatccca tgatgataag cataaagaat caacacaaag aaaaaaaaca gaccaataat
    24181 gggcatgatc tgaagacatt tttgtaaaac tgatcctttt ttagacatct atattcccca
    24241 catctttttt catttattaa aactgcctcc t
//
LOCUS       DAPBCF010000039        23672 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.040, whole genome shotgun sequence.
ACCESSION   DAPBCF010000039 DAPBCF010000000
VERSION     DAPBCF010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23672
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.040"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            287..694
                     /locus_tag="RD508_001937"
     CDS             287..694
                     /locus_tag="RD508_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736491.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            708..1109
                     /locus_tag="RD508_001938"
     CDS             708..1109
                     /locus_tag="RD508_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736492.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1111..1482
                     /locus_tag="RD508_001939"
     CDS             1111..1482
                     /locus_tag="RD508_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736493.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1518..1820)
                     /locus_tag="RD508_001940"
     CDS             complement(1518..1820)
                     /locus_tag="RD508_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736494.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2069..2269)
                     /locus_tag="RD508_001941"
     CDS             complement(2069..2269)
                     /locus_tag="RD508_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7736495.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(2574..3806)
                     /locus_tag="RD508_001942"
     CDS             complement(2574..3806)
                     /locus_tag="RD508_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDT7736496.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            4060..4629
                     /locus_tag="RD508_001943"
     CDS             4060..4629
                     /locus_tag="RD508_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7736497.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(4807..5247)
                     /locus_tag="RD508_001944"
     CDS             complement(4807..5247)
                     /locus_tag="RD508_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDT7736498.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5405..6169
                     /gene="map"
                     /locus_tag="RD508_001945"
     CDS             5405..6169
                     /gene="map"
                     /locus_tag="RD508_001945"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDT7736499.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            6201..7124
                     /locus_tag="RD508_001946"
     CDS             6201..7124
                     /locus_tag="RD508_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDT7736500.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            7200..8339
                     /locus_tag="RD508_001947"
     CDS             7200..8339
                     /locus_tag="RD508_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HDT7736501.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8332..9132
                     /locus_tag="RD508_001948"
     CDS             8332..9132
                     /locus_tag="RD508_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7736502.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            9132..9959
                     /locus_tag="RD508_001949"
     CDS             9132..9959
                     /locus_tag="RD508_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7736503.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            9937..10671
                     /locus_tag="RD508_001950"
     CDS             9937..10671
                     /locus_tag="RD508_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7736504.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            10771..11637
                     /gene="rfbA"
                     /locus_tag="RD508_001951"
     CDS             10771..11637
                     /gene="rfbA"
                     /locus_tag="RD508_001951"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDT7736505.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            11651..12223
                     /gene="rfbC"
                     /locus_tag="RD508_001952"
     CDS             11651..12223
                     /gene="rfbC"
                     /locus_tag="RD508_001952"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HDT7736506.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12245..13273
                     /gene="rfbB"
                     /locus_tag="RD508_001953"
     CDS             12245..13273
                     /gene="rfbB"
                     /locus_tag="RD508_001953"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDT7736507.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13371..14222
                     /gene="rfbD"
                     /locus_tag="RD508_001954"
     CDS             13371..14222
                     /gene="rfbD"
                     /locus_tag="RD508_001954"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HDT7736508.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14257..16290
                     /locus_tag="RD508_001955"
     CDS             14257..16290
                     /locus_tag="RD508_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736509.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16334..17614
                     /locus_tag="RD508_001956"
     CDS             16334..17614
                     /locus_tag="RD508_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HDT7736510.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            17824..18630
                     /locus_tag="RD508_001957"
     CDS             17824..18630
                     /locus_tag="RD508_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7736511.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            18642..19862
                     /locus_tag="RD508_001958"
     CDS             18642..19862
                     /locus_tag="RD508_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7736512.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            19852..21438
                     /locus_tag="RD508_001959"
     CDS             19852..21438
                     /locus_tag="RD508_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7736513.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21477..23615
                     /locus_tag="RD508_001960"
     CDS             21477..23615
                     /locus_tag="RD508_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7736514.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALKMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     ILEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
BASE COUNT         7568 a         3941 c         4851 g         7312 t
ORIGIN      
        1 tgaggggaag tacatatagt tgttgatata gttgctaata ttgttagcta atttgttagt
       61 aaaactgtat acgaatttag atagtaaaaa aacagtttgt tccttatata gaggcacttt
      121 tactactgat taaatgtcag atatgcttac aaatatactt ataaatatgc ttacaaaatt
      181 agctaatatt tccgttgaca aagctttgtt actattgtta aactaaattg actagcaaaa
      241 gtgaaacata aatttattaa ataaatgtaa aaattaggag aaatcaatgt cttatagagt
      301 acaattaata atttcagaag atgtagaaag tcagcaattt ggcactaatg ttattaataa
      361 agtaattaat ccagctcttt ctattaatgc gcctttaatt cctactgctt tatcattttc
      421 tgtaacagct gtggtgtctg agatagagga tacagaaaag ataaaaatag tagaaattga
      481 agttttaaac aagaatgaaa aacaaatttt ttctacgggt gaagtatcgg taagcttgcc
      541 tcctcaagtt aacgatataa actttaatat aaacgccaga aatgtcttgg ttgaagaagc
      601 aggagagcat tatgctgttg ttaaatttaa tggaactgag attggaaggc aaatctttga
      661 tatcaaggtc aacaaaccag tggaaaaaaa ttaaggagac gatacggatg cttgatatag
      721 taccatcaaa tacacatcgg agtggtagct taataaattt tgctgcgatt tttgcttgcg
      781 catcggtaat tctagcatct ccagttgttg tggatgcaag ttctactccg aaaactaaaa
      841 atgataatca acttgtaatt actacaaaaa atgagattaa cacaatttca agtaatgatg
      901 gcaaaatttt tgatgtgata aatacggttt taaaaagaaa agctgaaatc aatataaaat
      961 atgatgaaga tttaaacttg tatttctttg ttatcaaaac aacatctgaa ttgttttcct
     1021 cagattacga tgttttggat actctcgata atgtattatc tgactataaa tatatgggga
     1081 aatctgtagt agcaactttg ggggaataaa atgtttgact ttaatgaata tttatctatt
     1141 tccaaacaaa ttgaatcaga tgataaatat aattctaaag aatcttatag aagaactgct
     1201 gtttcaagag catactacag tgcttttaaa aaatctgatg agtatttgaa agaaaattat
     1261 gatattattt ataatggaag tagcggaaaa ggaagccacc aaaccgtttg gaatttgttt
     1321 tcaacagtta aggaattgaa taccttagga atacataata gtgggtatag aatgttagag
     1381 aaaagaaaat gtgctgacta tattcctaat gaaaccatta cgaaaacaga tatggcgctg
     1441 atgaatcgag aagcagaaaa aataataaac aaactcacct aatgaatttc aagcgagttt
     1501 gtttgttatt tttttattta atctttgtat ctttctggat caacgaaagt atactttata
     1561 tagtcataac gccgatgatc gctacgtgcg tccggcacgt cagtcacgat atcaaacaaa
     1621 aagtatacac ccttcttcat tctagttttc gcagcaggaa ttttgaaata gttcttatta
     1681 gaatagtaga gattgattaa taagctatct tcgattgcta aaaagaaaac ttctgaattc
     1741 catactttat aaaaatcttt gataaatcta ttcgaagggt caaatttaaa ccataattgt
     1801 gtttttcctt ccatcagcat aaaagttcac ctcaaaaaga gtatacgaac gaatgttctt
     1861 tttgtgaagg cggaatttaa tatactgaat aatagaaaac aagtacttgt gccaaattat
     1921 gtgccaaaaa aattcgaatt caacaaaatg taaacaaata gaaaaccttc tatattaaga
     1981 tttcctgcaa taacaaacac aacagaagac gtgtaatagt tagtcaggaa cgtacaaata
     2041 acccctgtat cctttgcggt acagggggtt attttgtata agtagacatt gtagtttcta
     2101 aactgctatg tcctaaacgt ttcgatacgc taagtatatt tactccttga taaagtaaaa
     2161 tagatgcatg cgtatgtctt agtccatcaa taaacagtcg aagagaaaat agggaaaaat
     2221 tgattactaa agaaaaactt actaggtcga cggtgtagtt gattttcata cttcaataga
     2281 ttcgaattaa acgatttcga ttggcttata ccagtcctat ccaacgaaag atatatcgtt
     2341 cttaactcta gcggtataac ttgaagcttt acgtaaagcc aatgggaatg aactggagat
     2401 gactttttat tatttttagt aatagctgat gggttaatac ttacaacttt ccttttcaaa
     2461 gtaccatata aaaaaacggt ggggttgttt agcgaaataa aggatctaag ccaatagctt
     2521 agatccttta ttctatgctt tatattattt tttgcatgtg tgcgaaagta tactcaagcc
     2581 caatcgccat ttcggaaaat cggtactgta gagccatctt cacggattcc gtcgatatcc
     2641 atcttgtcag atcctaccat gaaatctacg tgggtttgac ttctattcaa tccagcttct
     2701 gctaattctt catcggacat ttctgtaccg cctttcacac tgaaggcata agcagaacct
     2761 agtgctaagt gattcgatgc gttttcatca aataatgtat tgaaaaagat gatgccagat
     2821 tgagaaatag gtgaagggtc aggtacaagt gcgacttctc ctaaacgacg cgcaccttca
     2881 tctgtatcaa gcagttttgc taagacatct tctccttgtt cggcagaaaa atcaacaact
     2941 tttccatctt taaaagtaaa tttcataccc gagatgatgg tgccagcata actcagtggc
     3001 tttgtacttg aaatgtaacc atctactcga tgactgtcag gtgctgtgaa cacttcttcc
     3061 gtcggcatat ttgccatgaa tttttctcca cgagcattat agcttccagc gccttcccaa
     3121 agatggtttt taggcaatcc gataatgata tctgtaccgg gagcagtata gtgaagggca
     3181 gaaaattgtt ctcgattcaa ttcttctgct ttttttgcta atttttcatc atgcttcttc
     3241 catgctaaga cagggtcttc ttcatagaca cgagtcgttt tgaaaatctg atcccataat
     3301 gcctcaactt gtttttcttc tggcagttct gggaagactt ttgctgccca ttgtttacca
     3361 gccgcagcca cgacagtcca actgacttta tttgcttgag ttgccttgcg taaattcatt
     3421 agtgctttgc cattcgctga ttgataagac gctactcgat ggctatctac accagcaaat
     3481 gcatcgggat cggcagaaac aacgctgatc ctgcttgctc ctttttcaag ccattcatcc
     3541 gcttgatcga ttttagattg tggtacattc tcaatacgat ccgttgcagc atgtaaaaga
     3601 aattctcttt ggatctggtc gtcagtccat tgaacgataa cctcagcggc tcctagttta
     3661 taagcttctt gtgtgatcaa tcgagcaagg ggtgcctgtt ccacgctgat ctgtaaaaca
     3721 actgtgtgtc ctttttctgt ggctacgcca gtttctgcaa ttaagcgtgc atattttttt
     3781 agaagttcat taaaatcaga taacataata aaaattcctc ctcaccattt tttctggtaa
     3841 ctattagcat gataccattt aattatgatt caaacaatga ggctttaaat aaaaaaagga
     3901 ggttattttt ttaaggttaa gtttcatgat atatgttact acttgctatt tcagcttgtg
     3961 aagaaaatca aaaactaatt ttgcatatca aaaaaacatg ttacaatgaa attaatcaat
     4021 ggtggaagcg ttataaaaaa attaaggaga ttaaaaaata tggcaagaaa aaagacgatt
     4081 actagagaac agattttggc agctgcttat gaagtagctg ccaccgatgg atttacacga
     4141 tttactgcga gaaacatcgc gaacaaaatg aattgttcca cgcaaccgat ttatcttgag
     4201 tttaaaaata tggatgactt gagacaagct ctttttgagc agatctatga tcatttacaa
     4261 tatgaagtgt tcactgttga gcatacaggg aatacgatta tcgatcttgc ttttaattat
     4321 atccattttg caagaagaga gaagaagttg tatcgttcac tgtacttaga agaatatggt
     4381 ggaggaaaag agatgcagaa tttctcttat acttactttg tgaatacagt gaaacgcgat
     4441 ccagcttatg tgaatctttc agaagagcag atcgaatctt tgtataatgg gacatggatc
     4501 atagctactg ggatcgcagc tttgatgtct tcaagcatca tccatccaac tgatgaacag
     4561 attgaaaaga tgatccaaga cagtatagat gctatcttga aattcaaaga accaatcgaa
     4621 atcgattgaa tatactcaaa agttccacaa atcagtaggt aacaagagat gtgtcaaaat
     4681 aaggaaaagt tcgtttttct tacagcgtat gcatttttaa ctcccgaaga actcttccat
     4741 gaatgcaatg aataaaagag ccatccagat tgaataaatc tggatggctc ttttattgca
     4801 agtatattaa atttttgcga ctagttcttt agcgaaagct tctaaatttt cgatatcttc
     4861 ttcttcagca ttcagatcca ctttaacatt ttcggctcct tttgatgcgc ctgtttttgc
     4921 aaaagcagca tcgaaatcat ccaccgattt gcagaattca tcgtaaaaag tatcaccaga
     4981 tccgcagaca ccgtaaattt ttcccaatag atccaattct tgcaagtctt cataaaagtc
     5041 tacgatctca tcaggcagat cgccatcatc gtatgtataa gtagctacta cgcaaatatc
     5101 tgcctcctcg aattcatctg catctacttg ggtacattcg ttgatttcga cttcgatatc
     5161 cagattttca aatgcttctg caacaatatc ggcgatttct tcagtgtttc ctgtcatgct
     5221 agcatatacg atttttgcta aagccatgat gtgcctcctc gtttataatt atttaacaat
     5281 tatgaattat accaaaacat cattgaaaag aaaataaaac ctaaagacac ctggggaatg
     5341 tcatttggct aaatgtatgc cgctatgtta aaatgagagg gatttgtaaa aaggagacga
     5401 aaatatgatt actttaaaat cagcacgtga aattgaaatg atggcagaat ctggagcttt
     5461 attagcagat gtacataaaa atctgcgtga ttttataaaa ccaggaatca caagttggga
     5521 tattgaggta tttgtcagaa actatatcga gagtcatggc ggaattgctg cgcaaattgg
     5581 ctttgaaggg tatgaatatg cgacttgtat cagtataaat gatgaaattt gtcatggatt
     5641 ccctcgtaaa aagcctttga aaaacggtga tttggtaaaa gtcgatatgt gtatcgattt
     5701 gaaaggcggc atttctgatt cttgttgggc ctatgtagtt ggagaatcta cacctgagat
     5761 cgaccgattg atggaagtaa cgaagaaagc tttgtacatc ggtattgagc aagcacaagt
     5821 agggaatcgg attggtgaca tcggtcatgc tatccaaact tatgtagaag gcgaaaatct
     5881 agcgatcgtt cgtgatttta ttggtcatgg cgttggtcct acgattcatg aagaaccagc
     5941 agttcctcat tacggagaag ctggaaaagg gttgcggttg aaagaaggca tggttatcac
     6001 gatcgaacct atggttaata ccggaacttg gaaaatgaaa atggatccta acggctggac
     6061 tgcgtataca agagacggcg gactttcttg ccaatatgaa catacattgg ctattactaa
     6121 agatggtcca agaattttga catcacaagg agaagaaggc acttattgat ctatccagtc
     6181 aataggtacg ggagaggtac atgaaagttt ggaacaaaat aaaacaaaat gaaaatctga
     6241 tgcgctttat tgagacgact caaaagcgca tcactgattc agaaatgagt acgacctctg
     6301 tcgtcgttgc ttattattta ctcttgtctt tatttccatt gattattgct tttggtaata
     6361 ttttaccgtt tctccacatc gatcaagaga ctgtactgac ctatttacga gaagtgattc
     6421 ctgagaccgt ttaccagttt atcggtcctg caatcaaaga ccttttgaca caaagttcag
     6481 gaggcttgtt atccgtttct gcattagcgg ctttatggtc tgcaagtcaa agtatcaatg
     6541 ctttgcaaat tgcgatgaat aaagcgtatg gcgtagaaaa tagaaaaaat tttttgatcg
     6601 tccgtttctt ctcactaatt gtcattgtct tgttcatgat tgctattagt ggggtaacta
     6661 tcgttcttgg gttgggacag ctgattttgg atgctattca gccaatcgta caaatacccg
     6721 tgaactttat cgatcagttc caaactttga agtggccaat cacattggta gctttatttg
     6781 tcatcatgtt cttgatttat ttaattgtcc ctaatgctca gttgaagttg aagacgatca
     6841 ttccgggcac gatcttcgct actgtcggct ggatgctgtt atcacaagtg tttagtatct
     6901 atgctaggta ttttgcaacg aggatcagcg gttatcagat cataggaagt tttattgtac
     6961 tcatgctttg gcttaatttt gctgctacga tcatcatttt gggcggaatc atcaatgcag
     7021 ttgttcaaga atacgtgacg ggtcatcaaa tcaaaaaacg tcgagatcca agccgaaaat
     7081 ggttcaataa attgaaaact aaattttctc ataaaaaaaa gtagaaacaa gagttcttat
     7141 tgtaaattta tatcagtaat ttataataat tatgactctt aattaaagta ggtgcccata
     7201 tgcttgtttc ttttagtatg gttataagat tttttctgac aattttatta tcactgatat
     7261 taacacctgt attcaaaatc atttcagtac aaacaggtat ggtcgacaaa ccaaatgaaa
     7321 gaagaataaa taaagttcca atgccttcag cgggcggact gcctatcttt atttcatttg
     7381 ttatatcgac tttattctta ttccgtaaaa ttatccctca atcgtatatt gtaccgatct
     7441 tgattgcttc tttagtaatc atagtcacag gagtgctcga tgataaatat gagctgacac
     7501 ctaaacaaaa aagtataggg atcttgattg cttctcttat tatttatttt gtagcagata
     7561 tacgtattga ttccttcacg cttcctttta ttggatatat ccaactaggc tggcttagtt
     7621 ttcccgtaac gattttttgg atcttcggta tcacgaatgc ggtcaatctg attgacggtt
     7681 tggatgggct ggcggcaggg atttcattga tcggtttaat tacgatagga atcattggat
     7741 attttttcct ccatgcttct acagtgtata ttccagttgt tattttctgt cttgtagcaa
     7801 gtattatcgg tttttttcct tacaattttt atccggcaaa gatttattta ggcgatacag
     7861 gagctctatt cctagggttt atgatggccg tcctttcact acaagggctg aagaacgtga
     7921 cttttgtttc atcgatttct ttgctgatcg tcatgggagt gccggtaaca gacacgtttt
     7981 ttgctatcat taggagaaaa gcaaaccgtg tttctttttc tacagcagat aaaaaacatc
     8041 ttcatcaccg actaatcagt ttaggcttta ctcataaagg tgctgtcctg acgatttatg
     8101 cgatggcttt gatgttttct ttcacagcta tggtcatgaa ttatactgga agaatcggaa
     8161 cgatcatatt gattattgcc atgttgtttg ctgcaatttt attatttgaa ttgattggtc
     8221 tgatcaatga gaaacatcag tttattttaa aaacattgcg atttttaggg aataaagagt
     8281 accgtacgca agtaaaacag aaatatttga agaaatggaa ccgtcatata gatgaataac
     8341 aaattaaacc agccgatcct tattagtatt gtgacggcaa acagtgataa aatttttcgg
     8401 acactagata attttatttc aactgtaaaa gatgaaacag cagtaaaaat ccgaattttt
     8461 gacaacaatt cacttcccga gtacaaaaaa agactaacag agtataggaa atatccctac
     8521 atcgatatct attttcatga tgaaaattcc ggatttggtt atggacataa tcacaatctg
     8581 atagctagcg attctcgcta tggcattatt tgtaacccag atattttagt ggatgaagag
     8641 acagttacag cattggtctt gttattgaaa gaacatccgg aatgtgcgat gttagcacct
     8701 aagattctta atgaagatgg aacaactcag cacctcatcc gtgagcagct ggctgttttt
     8761 gattacgttt tgcgctttgt gcctttcaaa tgggtcaaaa aaaagtttga caaacgactg
     8821 gctgtgtttg aatgccgagg attgcctact gatgctaata gttatgtacg gatgatctca
     8881 ggtagtttta tggtagctga tattgataaa tttaaagaga taaaggggtt tgatgagcgt
     8941 ttcttcatgt actttgaaga caacgacttg tgtttgagtt ttgaaaaagc aggttacaag
     9001 ttattgtaca caccctttta tgcagttatc catttttacg ggaagggtgc gcatcgaaat
     9061 gcaaaactgt ttcgcgtgtt tttgacttct atgatgaaat ttttcaataa gtgggggtgg
     9121 cgttttttct gatgaaacca gaaatattag tagtcgttgt gctttatcag caactattca
     9181 gtcaatctcc agcttatgga ccattaagca aagcacttag cgaaaagcaa attcagctta
     9241 ttatttacga taatagtcct caaaggcagc aaaatgagct gtttgaaaaa gaaaatatcg
     9301 tttatcatca tgatccgcaa aatcctggtt tagcggtggc ttataatttt gcgttgtctc
     9361 aagcagatga aggaacacgt tgtctcgtca ctctggatca ggatacgagg ctagtcgacg
     9421 attattttga actattgcgt aaagtaacct ttacagatga atgtgttgct gcagttccga
     9481 tgattttttc tgggagccga caagtttctc ccctatattc agatcgttat atcaatcgta
     9541 cagctcaagc agtagaagtt gaaggcccaa cagctgaacg aatcatggca atcaattcag
     9601 gtgttgcctg gtctgtcaaa tttctaaaaa agattggcgg gtttaatcct gctttttctt
     9661 tagatttttt ggatcattgg ctgttttgga aagtggatca gttggaaaaa actgtggaga
     9721 tccttcctgt acgaatggaa catgatcttt cggttttaga ctatgaaaaa gtttcaagta
     9781 atcgataccg ttctatttta caagcagaaa atcgatttta tcatgaatat gatcaaaggc
     9841 atttatccag tcaccgacga caattattgt taagaacagc taaacagttc ttgaccgtca
     9901 aaaaccggca tatctggcgg atgactttgc gctcatatgt taagaattgg aaggtgtgaa
     9961 ttcgtgcgtt cggtttgtat agctaccttt aatggaggca gatatttaag agagcagtta
    10021 gatagtattt tatctcagct ttcagcagaa gatgaagtag tcatttctga tgatgggtca
    10081 gtagatgata catgggatat attaactgaa tacgcagaaa aagataagcg aatccagctt
    10141 ttttcggggc ctcgtcaagg attgatcgct aattttggtt atgcgatcca gcagacgaaa
    10201 ggagatctaa tctttttggc agaccaagat gatgtttggt tggagacaaa agtgaaaaag
    10261 atcactgact attttgagca gaatccggat cagctagtag tagtttctga tttaatcatt
    10321 gtggacagcg agctgcaaga gatccatgat tcgtattttt cgtttcgaaa ttccaaagaa
    10381 ggatggctta ataatgtgat aagaagtcac tatattggtg ctggtatggc tttccggtct
    10441 tctttaaaac ccgatatttt gccgatcccg tcagaagtgc cgatgcatga tatgtggatt
    10501 ggtttgctgg gaggaaagaa gactgggttc ctaagagaac cgttaactct gtaccgaaga
    10561 catgatttaa acgcgagtga gattgaaaca cattctaaat tacggcaaaa aatttcttgg
    10621 cgtgttcatc tgattacggc gttgatcaaa cgaaaatggt ttaaacgttg ataaaagatg
    10681 tttaaatcct taatatttcc atgacaaata taacaattga tgagataata acaaagtgaa
    10741 atttgaaatc aaaaaggaga gcagatatcc atgaagggaa tcattcttgc tgggggcagc
    10801 ggaacacgtc tgtacccttt aacaaaggca acatcgaaac aattgatgcc gatttatgac
    10861 aaaccaatga tttattatcc aatgtctact ctgatgttgg cgggaatcaa agaaattctg
    10921 attatttcaa cgccacaaga tacaccacgt ttcaaggaat tatttggaaa cggaaatgat
    10981 ttaggactgc agatcgaata tgcagtacaa gaaagtccag atggattggc acaagcgttt
    11041 atcattggag aagaatttat tggagatgat agtgtctgct tggtattagg ggacaatatt
    11101 tactatggtg gcggtctgtc taaaatgttg caacgagcag cttcaaaaga tacaggcgcg
    11161 acagtatttg gctatcatgt caatgatcca gaacgctttg gtgtagtaga atttgatgag
    11221 aatatgcaag ctttgtcgat tgaagaaaag cctgctcagc caaaatcaaa ttacgctgta
    11281 actggccttt atttttatga caatgaggta atttctatcg ctaaaggtat caaaccttca
    11341 gaacgtggag aactagagat tacggatgtc aataaagcat atttggataa aggaaaacta
    11401 tccgtagaac ttatgggacg cggatttgct tggcttgata caggaacaca tgaatcattg
    11461 cttgaagcat ctacctttat cgaaacaatt gaaaaacgtc agaacttaaa agtggcttgt
    11521 ttggaagaaa ttgcttaccg tatgggctac atcgataagg aacaattgct ggcccttgca
    11581 cagccattga aaaaaaatca atacggtcaa tatttattga atttggccgc tgaataagga
    11641 gtccttacag atgaaagtaa cagatacaaa attaacagat gtcaaaatcg tagaaatgga
    11701 cgtctttggc gatcatcgcg gtttcttcac agaaagttat tcaaaagcaa aatttgcaga
    11761 acatggattg aaatatgact ttgttcaaga caaccattca ctatcagctg aagctggtgt
    11821 ccttcggggg cttcatttcc aaaaaggaga agctgcacag acaaaattga ttcgggtagt
    11881 cactggagca gttttagatg tagtagtgga tatccgcaaa ggtagcccga cttatggtca
    11941 atgggacgga tttatcttat ctgaacataa tcatcgacag ttgcttgtac ctaaaggata
    12001 tgcccatgga ttcgttactt tgacaccaaa tgtgaacttc ctttataagt gtgataatta
    12061 ctataatgca gaagcagatg ggggcatcgc atttgatgat ccagatttag cgattgattg
    12121 gccaattgat ccatcaagag cgattatgtc ggaaaaagat caccgtcatc cgacattaaa
    12181 agaatttgaa gcagaaaatc catttgttta cggagaaatc taagaattaa ggagaaattt
    12241 tcttatgaaa aacatcattg ttaccggagg tgccggattc atcggctcta atttcgttca
    12301 ttacgtggta aacaatcatc cagaagtgca tgtcactgtt ttggataaac tgacttatgc
    12361 aggaaacaaa gagaacttgg ccggacttcc tagcgatcgc gtagaattgg tcgtaggaga
    12421 tgttgcagat gcagaattag tggaccgtct agtaaaagaa gcggacgcag ttgttcatta
    12481 cgcggcagaa tcccataacg ataattcatt aaaagatcct ttcccatttg tacaaacgaa
    12541 tatcattggt acgtatacac ttttagaagc ttgccgcaag tatgatgtac gctatcatca
    12601 cgtatctact gacgaggttt acggcgatct tccattacgt gaagacctgc caggacatgg
    12661 ggaaggcgaa ggagaaaaat tcactgcgga aacaccatat aatccttcaa gtccatattc
    12721 ttctacaaaa gctggttcag atctgttagt aaaagcatgg gtgcgttctt ttggcttacg
    12781 tgcaaccatt tcaaactgtt caaacaacta tggtccttat cagcatattg aaaaatttat
    12841 tcctcgccaa gtaacgagta tcttaagcgg tattcgtcca aaattatatg gcgaaggaaa
    12901 gaatgttcgt gactggatcc atacgaatga tcattcttca gcagtgtggc tgattttgac
    12961 gaaaggcaga attggcgaaa cctatctgat cggtgcagac ggtgaagaag ataataagac
    13021 cgtgatggaa ttgatcttag aaatgatggg ccaaccaaaa gacgcatacg accatgtaaa
    13081 cgaccgcgca gggcacgatt tgcgttatgc aatcgattcg acaaaattgc gagaagagct
    13141 aggttggcag cctgagttta cgaacttccg tgatgggttg gctgacacga tcaaatggta
    13201 cgaagaacat gaagactggt ggaaaaaaga aaaagaggcc gttgaagcag catatgccaa
    13261 aaatggacaa taatacagag gaaatttcac tgtattaatg gaaaaacaca tgtgaggcag
    13321 gcgctcgcct gtctcttttt taaaataaaa atcaaggagc ggataaccat atgtttttat
    13381 taactggagg aaatggacaa ttaggtacag aattgcgcca tttattagat gaaaaaaatc
    13441 tgccatatgt ttcaacagat gcaaaagact tggatatcac agatgctgag aaaacaatgg
    13501 cttatattac agaattaaaa cccgatgtta ttttccattg cgcagcttac acagcagtag
    13561 ataaagcaga agaagaagca aaagaattag atgagaaaat caatgtcgat ggcacaagaa
    13621 atgtagcact tgcagcaaaa gctgtgaatg cacaattcgt ctatatcagt acagactatg
    13681 ttttcgatgg aaaaaacaaa aatgtagaat acgaagtaga cgaccaaacg aatccactaa
    13741 atgaatatgg tcgtacgaaa ttattaggcg aaaaagcagt agaagagatt ttagaagact
    13801 attatatcat acgaacttct tgggttttcg ggatctatgg acacaatttc gtcttcacga
    13861 tgcaacgcct agcggaaacc cgcgacaaac tgactgtagt aaatgaccag tttgggcgac
    13921 caacttggac acgtactttg gcagaattta tggtatatgt catcgaagaa aaagcaccat
    13981 ttggtattta tcatttgtcg aacgaaaata gctgttcttg gtatgagttc gcaaaagaaa
    14041 tattgaaaga tacagatgta gaagttgcac ctgttacgtc agaagaattt ccgcaaaaag
    14101 caacacgtcc gcagtattca gtcatgagcc tgaaaaagac agaagcgtta ggttttgtca
    14161 taccaacttg gcaagaagca cttgcgcaaa tgctggaagc tgccaaaaaa atgaataagt
    14221 aatttccttt ttatcaaata gaatttggag catgatatgg aaaaacaaac aagaagtgca
    14281 cgacgaaaag aaaagccaaa agcgaatcag gcagattcga atttggtgct tgacctgttt
    14341 ctaaaactcc gctatcttat tggcgtttta gtcatcgtgg tcatcgttac ttttaattta
    14401 aacggaagtt cacttggtgt ttgggataaa tatgtgtcgc aaagagacga tgggaaaaaa
    14461 actgatgtga tttttggaca gaatcgggaa gtgcggtcag acgaatggct ggtgcagaca
    14521 cctttttacc tctcacaagc tgaagaggac ttttcgttgg tgaacgagga ttattcatta
    14581 aacggacaaa acatgatcat tgcgtataat tctcctgtaa aggatattac ggttatcgga
    14641 aaaccattca actggggatt ctttttcctc ggaagagatc gaggactttc cttttattgg
    14701 gcgatgaaat tagtcgtcat ggtcttgctt ggattcgaag tactgatgat attaacgaag
    14761 aggaaaaaag ctctatcgct aatcggtgca tttgcgctga cattttctcc agcagtccag
    14821 tggtggttca tgcaacatgt gggcgatttg attttcttta ctttgggact gatgattgct
    14881 ttttatcatt atttctacaa tcatgataaa aaatggctac gaacgttgat gatgcttttg
    14941 gtggttattt tcggtattgg gtttatttta gtgatttacc cagcccatca agtgatgctg
    15001 gcgtacttgc tgatttttta ttttgttggc ctgcttattt actatagcaa gaaagtttca
    15061 tgggatctgt tggatgtagt gttgattgga ggggcagttt tatttattgg cggagtcatg
    15121 gttcatttct ggctaacgtc aaaagacgca ttgttagctt ctttgaatac cttatatcca
    15181 ggaaaacggg taagtactgg aggaaagtgg acgattggcg aatttttttc tttccttaca
    15241 aattggaaaa ttccttttga agatatcaac tattcgaata actctgaagt ggccctgttc
    15301 tatcactttt ttccaactgt attcctagca agtccatttg tgttatttgg caaaaaagat
    15361 agcgaacaaa agttactggg acgtattttg atgatttttt gtctgttttc tatcttttgg
    15421 attaccgttg ggttgccaaa atggctagca gaaatcactc tgctgtctta tgttcctcca
    15481 ttaagagcca tccttacttt tagttttgcg gcttgtttat tatcgatctg gtttatcgct
    15541 tatatttgga gagaagatgt tattcctatt tggtataaat tcattttgtt ggcagtaaat
    15601 gcatggtctt atttctatgc gattacgcat tcgaaaatgg ataattattt ttcggatttt
    15661 gaaaccatcg cagttgctgt gttgggaaca gtgattttag cttttgcatt atttggctgg
    15721 agacgcttgt tttacctcgc ttttgtcgcc ttagttatcg tatctggctt tttcgtcaat
    15781 ccagtcgtag aaggtacagg agcgattttt gaaaaaacac tggcaaaaga aatccaaaaa
    15841 atcgatcaac aagatcctgg taaagtttgg ttgtctgaag atgaattata taacttcacc
    15901 ccaacattgg gagtgaaatc cttcaataca gtacgctttt atccagatat agctgcatgg
    15961 aagaaaatcg atccgaaaga agaatacgag aagtattata atcggtatgc tcatacaaga
    16021 gcttttatcg ctaaggaaga tacaaagttc attttagatc gtccagatat gttttcggtc
    16081 acgttgaatt ttgaagacgc agaaaaatta gggatcgact atgtgatcag taaacgacca
    16141 ttaactgatt acaaccaatt atatgaagcg cagttcacgc agctatatgg accggataaa
    16201 gacggttata tgatttttaa agtagaatat ccggattatc cagatgtacc acaaacacaa
    16261 actcaggaaa atcagctagt cgtacagtaa taggctagct gagaataatc ctgaaatatt
    16321 agtagaaagg agagtgaaga taattcaagc aatcgtacaa aaatttgtca acaaaatgag
    16381 tgtcggtttc ttgcttttgt tgctgacgct agtctttttt gtttggacag caggggtagg
    16441 ttttccagca actttgttta tatataacaa tagttcatta cttatcgctt ttagtgtggc
    16501 tattttgctc attttaaatg tttataaagc aaaaggcgtc gattttcttt atctaggtgt
    16561 tgcgcttgcc cttttcattt tcttttctta ctttcgggaa ttaagaaatg agtctttatt
    16621 tggagactta ctgtttcctt tgattatttt attttgttta gtaattaaat ggatcgagtg
    16681 gacaaaatgg gatcgcggta tttatctgat tgtctttacg gtcttcctcg gaatcacgtt
    16741 atatcgtgta tttacagaga tccaagtacc agaaggacaa agcatctggg ctccaggcaa
    16801 ttcgctttct gatatttgga tcaatacgaa tacaatcgga agttctttga tgactcttgc
    16861 tttattgatc agtggatttg ccagttcttt tgaacgatgg tatgttcgaa tcatcggtgg
    16921 gatagcagtc gttgcagcct ttttaggtat ttgggtctgc caatctagag gtgcattagt
    16981 cgcgttgatt gtttttgcga tattggatct tttacctaaa tcgttgatgc gtgtcattcg
    17041 tgcgccattt attgcctaca cggttacgat tcttttagct ttgccgattt cttatctggc
    17101 ggctgtctct gaaaaagtca atttgtttac cggtcgagaa gatatttggc ataaattcta
    17161 tcagacgcta ggagaaaaat ctgaacaagt tttactagga atgaaaacat ttatcttcca
    17221 gcgaggaaac caatttttag gaaaccacaa tagttataat tctattttga atatctatgg
    17281 attgatagga tttgggattg ctgctttgct gcttatcctt tttattggtc gcttaacgtt
    17341 gaaagcagat ttatccaacg ggcagatgac ttttatctgg gccttttttg cggtgatgat
    17401 gcagtcattt atggaggata cattgacttc atacccatgg gttccgatta tttatatcct
    17461 gttggctatg gccgttcatc gatatgatga accagaagtt acggaggaat tctatgttat
    17521 ggaagaggca tatgacgata tgacttatga tgatacatct tatgaggaac aaccagatag
    17581 cgctcattct tccaggatcc aacgctatca ttgataggca caaaatacga gagaggctgt
    17641 gacaaccgtc gcagcctttt ttggtttatt gcaattgtct agcatcttct gtaaaataga
    17701 aacgttagag aaaatcttgt atcatagaaa attaagaaag aaataagaac gcagctcggt
    17761 accaaaaata tggtaaaatg gcacttgact gtaattcact gaaaatcgct tggaggaaca
    17821 caaatgttta aagatttgta tttatttatg aaggacattt atcagaacag aaaattactg
    17881 ctacagtttt cgatcaatga cttcaaatca agatatgcag gatcgttttt aggaatctta
    17941 tgggcgttta tcaatccgct atttactgta ttgatttatt ggctggtatt tggtgttgga
    18001 ctgaaagcac aaatgatcga tgcaaaatac ccatttatcg tatatttagt taccgggatg
    18061 attccctggt tcttcttctc agatgcattt gcatcaacta cggttgtttt tcgggaatat
    18121 acttatttag taaagaaagt cgtattcaat attcgtatct tgcccacgac gaaaatccta
    18181 tccaatctgt acacccattt attcttcatt ctgattggca tagctgtcgc gcttataaat
    18241 ggtatatatc cttcagcaat gtctttacag ctgatttatt atttattttg catgtgtgct
    18301 ttcttgacag gattgacttg gctgacggca tcgatccaac catttttacc tgatatcatg
    18361 caattaatta cgatcgtgct gcagttgatc atgtggacat taccgatatt atggagccct
    18421 aatcagtttg attcaggtct tgtaagcata ttgaaattaa atccgctgta ctatgttgtt
    18481 caaggttatc gtgagtcatt tttaagtgaa gcttggttct gggagcatgg aacatatact
    18541 ttgtatttct gggttttcac gttagtaatg ttcgtaatcg gctctgcagt gttccgtaga
    18601 ttgaaaccac atttttcaga tgtgctgtaa ggagaatagc tatgacagaa tatgcaatta
    18661 gactaaaaga tatcacaaaa tcttataata tgtacgcaaa accttcggat cgatttcgtg
    18721 aagccctcaa tccttttaag aaatcctatc atgatgtatt ttatgcgttg aaaaacgtga
    18781 atgtagaaat aaaaaaaggt gagatgatcg gtttcgtggg agaaaacgga tcgggaaaat
    18841 ctacaatgtt gaaaatcatt acgggagtac tgacaccaac atccggcacg atggaaatcg
    18901 aaggaaaaat ctcagctttg ctagaactag gatcaggatt caatcctgag tattctggct
    18961 atgaaaatat ctatttaaat ggaatggttc taggattttc aagagaagaa gtcgatgaaa
    19021 tggtcgatga tatcattgaa tttgctgaca tcggcgacca tatttatcaa cctgtaaaaa
    19081 cctattcaag tgggatgttc gttcgtctag cttttgctgt agcgatcaat gtgaatcctg
    19141 atattttgat tgtggatgaa gcattggcag taggagatct tgaatttcaa ctaaaatgta
    19201 tggaaaaatt tacagaaatc aagaactcgg gaaagacgat tttattcgtt tctcatgata
    19261 ttagttcgat tcgccgtttt tgtgatcgtt cctattggtt gaaaaatgga aaagttgtcg
    19321 aatatggtga tacgatggaa gtaacgacga attacgaaaa ctttttgaag aaaaaatcag
    19381 ttaaaacagt agatcgaaat aaaaaccaag tagaacgctt cgcagctcca gatatcgtag
    19441 acgtgacgaa agccgaattg ttggataaag ataaaaatcc agtggatatg ctggaacaag
    19501 gagaaaaact atacgttaaa gtaacctatg aagtaaaaga cgatacaatc aaaaatccag
    19561 ttttaggaat tgctctgcgt acagtcgaca atttttatgt gtgcggactc aatactctac
    19621 tagatggtat caagatccct tggaaaaaag gtgagaatat cttttatctg gagtatgaaa
    19681 agttaggttt gttagctggt gaatattatt ttgacgttgc ggtctttgaa gaaaatgcaa
    19741 cggttccttt ggtatacaag acaaaataca tgaacttgtt tgtcagcggt tcttatatcg
    19801 gagaaggcat cgtggtctta gaccataaat gggaagaagg gactcatagc aatgaaatat
    19861 gattttgaaa tggacctaga tgaacaaagc agtgtgggaa aaattgccgc acagatcaaa
    19921 ccaggaagta aagttttaga gtttggtcct ggaaacggcc gattaacgaa acatttgatc
    19981 ggagcaaaac aatgtgaagt gagcattgtc gagctagata aggaattgtt cgattttgtc
    20041 agcgagtttg cccaagatgg attttatgga gatatcgaaa gttttgaatg ggcaaactat
    20101 tatgctggac aaacatttga ttacgttttg tttgccgatg ttttagaaca tttggtagat
    20161 cctggaaaaa cgttgaagaa agttagagaa tttttgaatg aagaaggaga aattctaatt
    20221 acattcccta accttgcgca taattctgtc atgattgatt tgttcaataa tcaattgcca
    20281 tgggcttctt atggtttgct agatgaaacc cataattctt tttatactca tgatggcttc
    20341 caaaaagttt ttgaaaaagc aggattatac atcaatattg aagattattt gtacttagct
    20401 gtaggtgata cagaattaaa atcaacttat gaagaattgc cggaagctgt acgttatgat
    20461 ttcaaaatgc gaccatttgg cgaagtctac caatacttct tctcattgat gaaacatcca
    20521 gtagcacaaa gttccattgc gcagccgcaa aattctaatt atgtgaaagt attagaagta
    20581 atccagcaaa cgaaacaaga tgaaataatt caacaaatac cattcaataa tttcacaggg
    20641 gaaaatgaga cactaagttt ccatgtatca gaattagcag aacgaatggt gtttcgcttc
    20701 gcgcagcaac ctagctttat cgaattcagc gcagaagctg ctggagaaaa actcacattt
    20761 atcgattcaa atgctgtagt caaaacagta aatgattgtt atttgtttga tggtaaagat
    20821 ttaccagagt tctttttaac ggatattgca gggaaagaag tgactatcca ttgtcactat
    20881 cgttttatcg gagaattgac accaacaatg aaagaattgc tggaaacaat ccgtccaatg
    20941 gctgaagtta caaagcagct ttctgagaaa aatgatgaat tagaaagaga aaatcattat
    21001 cttattgaga ataatacaag attagatcag acgttgaaaa caaccataaa tcgctattgc
    21061 acgttgttgg aaagtgatga atggacaatc aaacatagat tagggcgacg taagaaagaa
    21121 acatcgaaaa aaatccaaga aaaagagctt tctctatgta ttgacgaaaa aatctgggat
    21181 gcagaaacaa agatattgaa aatcatcggg tggggaatcg ctaattcgga tcgccaacca
    21241 ttgtcctata agttatcagc cgaccaatca ccattttttg aagcaattcc tgttttacga
    21301 gaagaagtca atcaagcaaa acagctagct gaaggagcaa aagcaggatt tgaactgcgg
    21361 atcctttgcg agaaggaacg ttcattctta gttgaagcag tggctcaaaa tggtcaatca
    21421 tggatcattg aaatgtaaat aatgattaac ttataaagat aaggagtaaa cgaatcgtgc
    21481 aaaaaaaaga aattgccgta tttatcgatc aaatcactcg tgaacgggcc actggcgatt
    21541 tgcttattgt gggctgggca attgatgaag tgaccaaaga aatccctacg ataaaggtag
    21601 aaaaagaaaa tgtgattgct gaagcaacac atgtcgtaag attggatatc aatcatttat
    21661 ataatcttga tgttaagacc caaagcggtt ttaaggtacg tttatcaggg aaaatgagag
    21721 gaaaagcaat cttagacttc caaacagcaa gacatcaaaa tggcatagct gtgaaattaa
    21781 acggtaaata tccttatgat gacggcattg aatcttcatg ggaaagaaaa aaaagattac
    21841 tgaaaaaagg gataaattat gcaaggactc atggcgtaaa aaaagcaatc cgccgggtca
    21901 aactggaatt gaaaccagga tcgatcgact atgcagagtg gatcagtcgt catgagaaac
    21961 ctgatctgaa agagcaaagg aaagaagtac aaggatttgc ctaccgccca ttgatttcca
    22021 tacttatgcc tgtctataac gttgaaatca aatggctcga aaaatgcatt gattcggtac
    22081 ttgatcaaac gtatgatcac tgggaactat gtatcagtga tgatgcttct actgatccag
    22141 ctatccgaaa gtgtctagaa tcctatcaag caaaagatga tagaattaaa gtcgttttcc
    22201 gacaagaaaa tggacacatc agtctggcaa ctaattctgc attgaaaatg gcagaaggag
    22261 agtttatagc gctcttagat aatgatgacg aattacctcc atttgcctta tatgaagtgg
    22321 caaaagtgct aaacgtacat ccagaactgg atttgatcta cagtgacgaa gataaaatcg
    22381 atgcagatgg gaatcgcttt gacccgcact tcaaagcaga ctggtctccc gatacattga
    22441 tgggaaataa ttatatctct cacttaggcg tatatcggac aagcattgtt aaggaacttg
    22501 gcggtttccg taaaggatat gaaggctctc aagattatga tttggttctt cgtgtgacag
    22561 aacaaattcc tgcagaacac atttaccaca ttgaccgtgt cttgtatcat tggcggacga
    22621 tcccgggatc aactgcaagc aatggagaag ctaaaagcta catctatgat tctggagtga
    22681 aagcattgac agatgctcta tctagaagaa atatcaaggg aagcgtacat cctggcagaa
    22741 tttctggttt ttatgaaatc acttatgatg ttttgcaaga agacttggtc agtgtgatca
    22801 ttccaactaa gaatggctat gaagatctaa aaacttgtgt ggattcgatc atcgaaaaaa
    22861 cgtcttatcc aaattatgaa atcattattg cagataatgg aagtacagat cctaaaatgc
    22921 aagaattatt tgcagaatac aagcatcagc tgaaagaccg atttatcgtc gaattaattg
    22981 acattccatt caattattca cgtatcaaca atctggcagc agaaaaagca aacggcaaat
    23041 actttttatt cttgaataac gatacagaag tgattgaacc tgactggatg acagcgatgg
    23101 tttcttatgc acagtttgat cgaatcggct gtgtaggagc aaaattattt tatccggatg
    23161 atacaacgca gcatgcaggt gtattattag ggatcggtgg cgttgcagga catgcattga
    23221 ataactatga tcgaacacat tgtggttact ttggccgatt ggtcattgac gtcaattact
    23281 tagcagtcac tgcagcttgt atgatggtca aggcagctga cttcaatgct gtcaatggat
    23341 ttgatgaaat attagaagta gcattcaacg atgttgactt gtgcttgaaa gtttatgaac
    23401 tgggtcgtta caatgtctat gcacatcaag cagaattgta ccatttcgaa tctaaatcaa
    23461 gaggttatga agatacacca gaaaaacaaa gacgttttgc tggggaaatc aaaaaaatgc
    23521 aagataagtg gccttcttat attgctcatg acccatttta taacgataat ctaactaaag
    23581 aaggaatcgg cgatttttcg ttgagacctg attgattaaa agaactgtat tttcattttt
    23641 attaatgaaa atacagttct tttaatttaa tt
//
LOCUS       DAPBCF010000040        22303 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.041, whole genome shotgun sequence.
ACCESSION   DAPBCF010000040 DAPBCF010000000
VERSION     DAPBCF010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.041"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(48..1343)
                     /gene="purB"
                     /locus_tag="RD508_001961"
     CDS             complement(48..1343)
                     /gene="purB"
                     /locus_tag="RD508_001961"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDT7736515.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1356..2480)
                     /gene="purK"
                     /locus_tag="RD508_001962"
     CDS             complement(1356..2480)
                     /gene="purK"
                     /locus_tag="RD508_001962"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HDT7736516.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2473..2961)
                     /gene="purE"
                     /locus_tag="RD508_001963"
     CDS             complement(2473..2961)
                     /gene="purE"
                     /locus_tag="RD508_001963"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDT7736517.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3377..4684)
                     /locus_tag="RD508_001964"
     CDS             complement(3377..4684)
                     /locus_tag="RD508_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDT7736518.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4687..5268)
                     /locus_tag="RD508_001965"
     CDS             complement(4687..5268)
                     /locus_tag="RD508_001965"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDT7736519.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5384..5481)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5840..7132)
                     /locus_tag="RD508_001966"
     CDS             complement(5840..7132)
                     /locus_tag="RD508_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7736520.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7129..7752)
                     /locus_tag="RD508_001967"
     CDS             complement(7129..7752)
                     /locus_tag="RD508_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736521.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7755..8591)
                     /locus_tag="RD508_001968"
     CDS             complement(7755..8591)
                     /locus_tag="RD508_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7736522.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8608..9495)
                     /locus_tag="RD508_001969"
     CDS             complement(8608..9495)
                     /locus_tag="RD508_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7736523.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9511..10794)
                     /locus_tag="RD508_001970"
     CDS             complement(9511..10794)
                     /locus_tag="RD508_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7736524.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11477..12160)
                     /locus_tag="RD508_001971"
     CDS             complement(11477..12160)
                     /locus_tag="RD508_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDT7736525.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12178..12795)
                     /locus_tag="RD508_001972"
     CDS             complement(12178..12795)
                     /locus_tag="RD508_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HDT7736526.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12805..13629)
                     /locus_tag="RD508_001973"
     CDS             complement(12805..13629)
                     /locus_tag="RD508_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDT7736527.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13622..14182)
                     /locus_tag="RD508_001974"
     CDS             complement(13622..14182)
                     /locus_tag="RD508_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736528.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14356..15312
                     /locus_tag="RD508_001975"
     CDS             14356..15312
                     /locus_tag="RD508_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7736529.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMIHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15617..16573)
                     /locus_tag="RD508_001976"
     CDS             complement(15617..16573)
                     /locus_tag="RD508_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HDT7736530.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCERLLTFIRESQEDAREHQENYWLRQPLYYETCFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILARIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16678..17280
                     /locus_tag="RD508_001977"
     CDS             16678..17280
                     /locus_tag="RD508_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7736531.1"
                     /translation="MQFGRFRLGMRTIKSAIAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17368..18867)
                     /locus_tag="RD508_001978"
     CDS             complement(17368..18867)
                     /locus_tag="RD508_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HDT7736532.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMNEE"
     gene            complement(18883..19407)
                     /locus_tag="RD508_001979"
     CDS             complement(18883..19407)
                     /locus_tag="RD508_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDT7736533.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19582..21231
                     /locus_tag="RD508_001980"
     CDS             19582..21231
                     /locus_tag="RD508_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HDT7736534.1"
                     /translation="MFPFFKKKPLKLQNTIILVVCFSTFVSLIVSAILIRNFILSMNR
                     SSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIMIASNLDFIVVMDPEGIR
                     YSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFRYFVPIYYNQEIIGAVCV
                     GLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMKKVLLGLEPQEIAEQLSE
                     KTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDFEVGKKISDNLYDVLFKE
                     TIEHQTTVRTQSMYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGTKQ
                     YINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVPAI
                     AGFLLGKINEAKEQSVEMLLETDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQKHE
                     RNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLIHS
                     IVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21200..21916
                     /locus_tag="RD508_001981"
     CDS             21200..21916
                     /locus_tag="RD508_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDT7736535.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     LKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22018..>22303)
                     /locus_tag="RD508_001982"
     CDS             complement(22018..>22303)
                     /locus_tag="RD508_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HDT7736536.1"
                     /translation="ALKSNHLAGFATDVFANETEVFFRSFKPWETIPDPAIQQLVEMY
                     PRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPKARQLR"
BASE COUNT         6567 a         4807 c         3904 g         7025 t
ORIGIN      
        1 ttatttttgc tattctattt taattgaatt ttgcaactca ctcttcttta ttccaaacct
       61 actcgtttga atatcacgtc aacgtttttc aaatgatgat gataatcaaa ggcatcgtct
      121 atttcttctt tagataatac cgatgtgatg gttggatctt cttctaacag cgggcggaac
      181 tgcacttggt tgtcccaagc gtacgcagtt tttggctgaa caagatcata agcttcttct
      241 cttgtcattc ccttatcgat caatttcagc ataacgcgct ggctataaat caaaccaaat
      301 gttgcagaca tattccgctt catgttttca ggaaagaccg ttagattttt aacgatattg
      361 ccaaaacgat ttaacatgta attcaataaa atcgtggtat caggcaagat gattcgttct
      421 gctgaagaat gagaaatatc tctttcatgc cataatgtga cattttcata ggcagtgacc
      481 atgtgtccgc gcaccactct ggctagacca gccatatttt ctgaaccgat cggattcctt
      541 ttgtgcggca tagcagaaga acctttttga cctttcgcaa aaaattcttc tacttcacgt
      601 gtttcggatt tttgcaatcc gcgtatctct gttgcaaaac gttcaatact tgtagcaata
      661 agcgccatcg ctgagaaata ttcagcatgt agatcccgag ggagaacttg agtagagatt
      721 tcttgtggac ggatccccaa ttgtttacat acatactctt caataaatgg cgggatattt
      781 gcgaacgttc ccactgctcc tgagattttt cctgcttcta ctccttttgc cgcatgttca
      841 aatcgttcga tgttccgttt catttctgaa taccatgtgg caagtttcaa tccaaaagta
      901 gttggttcag catggacacc gtgtgtccga cccatcatca ctgtatattt gtgttctttt
      961 gctttttcgc caatgatttc cgtaaaacgt ttcaagtctt cccgtaaaat atcatttgct
     1021 tgcttgatga gatagccata agcagtatct acgacatccg tacttgttag accataatgg
     1081 acccattttc tttcttctcc caatgtttca gaaaccgctc gtgtaaacgc aacgacatca
     1141 tggcgtgtta atttttcgat ttccaagatc cgatcgatat caaatgatgc atgctcacga
     1201 atttttttca catcttcttg cgggatttca ccaagttctg cccaagcttc atctgctaaa
     1261 atctcgactt cgagccacgc acggtatttg ttctcttccg tccagatatt ccccatttca
     1321 gggcgtgtat aacgttctaa catgtttttt ctcctctaat cccaaatatt cgtttgtttg
     1381 atttcttcca gcgtttgctg gatgtcttct gtcaagatag tgatatgtcc catcttgcga
     1441 cctttttttg cttgtttttt tccatagaaa tggaattgcc agtctggctt attctcaatc
     1501 aagcgatagc tttccagcag ttgttctccc aaaacattga ccattactgc attgcttatc
     1561 aaacgtactt tttctcctaa tggccaacca caaatacctc gaatatgggc atcgaactga
     1621 ctcatagaac aagcttcaat agaataatgt ccagaattgt gaggacgagg agctaattca
     1681 ttcacatata gcccgcctgt ttttgttaaa aacatttcta cccctaaaac acctgaaagg
     1741 ctcactgctt ctgcaatcac acgggcaata cgctcagcct cctcgatcac atcctgatca
     1801 atcgcggctg gagcaatcgt ttcatgaaga atattgttgt ggtggatgtt ttccacgacc
     1861 ggaaaagtcg tgaaatctcc ttgaccattt cctgccacca tgatcgaaat ctctttttca
     1921 aacgggatcc atgcttctaa aacacaggtt ccttctctta aaaggtccat ggcaggagct
     1981 agatccgccc gacttttcaa aacatactgc cccttgccat catagccgcc tcgagtggtt
     2041 ttcaaaacac aaggatagcc gatcccgtca atcgcatctt ggatatccgt cggactgacg
     2101 atcgttgcat aaggagcaat cacgatgtta ttcgtttcca aaaaagattt ttctaacagg
     2161 cggtcttgcg taatcgcaag caagtctgtc ccttgaggaa taaatgacat gggtaaaatc
     2221 gcatttaacg cctctacact gacgttttcg aattcatagg taatgacatc tgttcttctg
     2281 gcaagctctt tcagcgcaaa ggtgtcatca tagacacttt caatgtgcca atctgcaact
     2341 tgtgcggctg gacaatcgct cacaggatcc agcacaccta ctttaaagcc catttctttt
     2401 gcactaatcg ccatcatacg acctaattga ccgccaccga cgatcccgat cgttgaacca
     2461 ggcaacaaag gtttaaccaa gttgatcact actttctata acagttttag ccaacattga
     2521 acgtctttca gccaatttag cctccaattc taaatcatac atggaaagca tctgtatcgc
     2581 aagtagtcca gcattaattg ctcccgcttt tccgattgct gtagtagcta caggtactcc
     2641 tccaggcatt tggacaatcg aaagaagcga atccaaacca tttaatgttc gtgattggac
     2701 cggtacaccg ataaccggca aagttgtttt tgatgcgacc atacccggca gatgcgcggc
     2761 tccccctgct cctgcaataa tgattttgat tccttttttt cgagcgtttt gtgcatattc
     2821 aaacatcaaa tctggggttc gatgagcaga aacgaccttt ttttcataag acacaccgaa
     2881 ttcatccaat atttgacatg cttctttcat tgtttcccaa tctgaagtac tccccataat
     2941 cacagagatt tttgctgtca ttgtttttcc tcccagtttt tctacattca tattttaaca
     3001 atcacttttt ttgatgtcaa agaaatttcg aatgttaaca aagaaaaaca ttttattgtt
     3061 cgtgtttatt aaagataaaa aaaaggaatg tgacaaaagt taggtcacat tcctttttat
     3121 ggataaacgg tgttctcctg ccaactcctc ggtcacaagg aacaatattc aacaaacatg
     3181 agaagctttt ttttgaaatt gttccttgtg actcggagat gaacggcagg ctcacgacct
     3241 cttccttcaa cggtgttcaa tcagctgacc ctcggtatta gctcaaacaa acggcaaaat
     3301 acgaggaact atttttccgt ttgtttctct aacaatcagg tcaaaacgct gatttcacaa
     3361 cctttctttt gctctattac ttcttgaagg cttcttccaa tatttcttca tcttttttca
     3421 atccattaaa gatcaaattc aatatgatag ccgtaatgct actcattacg atgccatttc
     3481 cagtgaacat ttgcaatgtt tgcggcattt gactgaataa tgtcggcgta acattgaaac
     3541 ccagcccaaa tccaacagaa acagcaacaa tcaatagatt tttatcattg ctgaaatcaa
     3601 cttccaacag catacggatt ccttggactg ccaccatccc gaacatgact aacattcctc
     3661 caccaagtac cggctcaggg atgatttgtg ctaacgcacc gattttaggg aataatccta
     3721 aaacaatcaa gaagaatgca gagaaataga tgggttttct tgttttgatt cccgaaagtt
     3781 gaaccaatcc gacattttga gaaaagccag tataagggaa tgtattgaaa ataccgccta
     3841 agataacggc aagtccttct gcacgatatc cctttttcaa ttcttcttct ccaacatttt
     3901 tcccagtaat gtcaccaagt gcaaaatata cacctgttga ttctaccatg ctgaccatgg
     3961 aaatgatgat cattagtaaa atcgaccata cgtcgaaagt tggtttacca aaataaaagg
     4021 gttgtggaac atggaacaac ggcgcatctc caatcgcgct cagatcaatc attcccatga
     4081 aagcagctaa gatgcttcct ccgactaaac caatcaatac cgcgattgaa cgaatgaacc
     4141 cttttgccag catttgcacg cctacaatta ggagaatcgt cacaaatgca agtagcagat
     4201 ttgttttgtc accaaaatca gctgctgttg cattacctcc acccattttc tcgattgcta
     4261 caggaatcaa agtcaaacca ataacggtga taaccgttcc tgttactata ggagggaata
     4321 gttttttaat tttagaaaag acaccagaaa ctaacacaac aaagatccca gaagcgataa
     4381 tagatccgta gatagctcct actccttcat tggttccgat caagatcagt ggagctactg
     4441 cttggatcgc acatcctaaa acgacaggca agccaattcc gaaaaatcgg ttaactgtca
     4501 attgcaataa tgtcgctaat ccacacataa agatatcaat tgaaatcaaa taagtcatct
     4561 gttcttgatt aaagcctagt cctgtaccga tcaaaagagg caccgctact gctcctgcat
     4621 acatcgctag cagatgctgc agccctaaaa ccgcagcttt tccattttgt gtttcttttt
     4681 ccacgattat gcgtcctcct caagaaactc aacttgtcca ttcgtcaagg aagcaatacg
     4741 cgcaagagaa acgactctca atcccatttc ttcaagtaac tgacgtccat cttggaaaga
     4801 cttttcgatg acgatcccga ttccttctac ttgcgctcca gcttgctggc ataattcgat
     4861 caatcctttt gccgcttgtc cgtttgccaa gaaatcgtcg ataatcaata ctttgtcttc
     4921 tgaagataaa aatttacgag aaatagaaat cgtacttgtc acttgtttcg taaaagaata
     4981 aacagaagct gtcaataatt cttcatccat cgtcaaactt tttgcttttc tagcgaagat
     5041 cattggaaca tctaattctc ttgcagcaaa taaagctggt gcgatcccag aagcttcaat
     5101 ggtcacaact ttcgtgattc cttgttcttt aaatacttct gcaaaccgtt ttcccatttg
     5161 ttccatcaat acagggtcta cttggtgagt gacgaagctg tcgactttta atacgccctc
     5221 gcctaatata cgtccgtctt tttgaatacg ttcaactaat tctttcactt tatttgctcc
     5281 tttatcattt attaataccg aaataaccgc ttttgtgcaa aaacctacta tgtttctgtt
     5341 aaagaaaaac accctccact ttatcataag aaaagaaggg tgaaatagcc aatcttttac
     5401 ttatagtcca gcatttacgg tactggctag aaactgtcat ccatattatg acgatatata
     5461 agtaggtatg taaaactaat aatagtgtaa attcattttc ttgcaactgt tttgcacgtg
     5521 aaggcagttt gccatatttg aataaaaaat gttgtttcaa atattgaaaa cagtctaaca
     5581 ctactttctg aaactgacaa cgtggtttac ttattttttt gtaaaatcta atgattttta
     5641 atgcattatt cctttttgtt cgggtttaaa tagttatttt tattttctcc tatctaaaaa
     5701 agcagcccac ataaaaagaa ggcatgacaa aaagcatgtc atagcccctt tttccgaata
     5761 aatagtgttc aaaagacagc ctatcggcaa taaggcaaga ttttataaac tacgggaagt
     5821 aatttccgta aatctattct tattctttta agctgacaag ctcgtcaatc actactgctt
     5881 ttcctgaagc aatagaatga tttgctgcga ttcctgtcaa aatcgacaaa ataccatcta
     5941 cgtgagttgc tgcccgattc cacggatctt cttctttttc ttcaccaaat agatcatcta
     6001 ataaacgcgg atctcctccg ccatgtccgc ccgcttcttg ttcgacgatt acctcatatg
     6061 gctcaccgaa catcggatag acatggatgg actgaagaac ggctgctcct tcatcctttt
     6121 tatctccacc tgcattgatg taagactttt cgatcacttt catttcgatc cgtcctttgc
     6181 tgccattgaa agaaacattg aatccttccc acggcatata cgcgtttagc gaatacgtca
     6241 aaatcgcacc agtttcatat ttgaccgtta cgcctagtgt atcttcaata gagatatcat
     6301 cggaaaatac actgcggtca cgaatatatc cactgtcttt ttctgcttct aaatacattt
     6361 ctcgcaattc ctcattggct gacaggtcta tagcaaatgg atcagcttta gctagttcgc
     6421 ttccatagca tcgactgtaa aatatttcta ctccgcgttt ctccgcatta tgcatcccat
     6481 aaaagtttaa tccaccgaat gcaaatacct tttggggacg gctgttcaac caaaaattca
     6541 ctagatcaaa atgatgggta gatttatgaa caagaagccc gccgctattg tgcttatttc
     6601 gatgccatct tctgaaataa tctgccccgt gttgcgtatt taacagccat tcgaagtgga
     6661 tagaaaacac atcaccaatc acatcacttt ctatcagttc ctttatcttc gtgtgatacg
     6721 gtgcataacg ataattaaaa gtgactcgca ggcttcttcc cgtctgtttt tggaccgtta
     6781 ttatttcttg agctttttcc tcatcgatag tcagaggttt ttcgcaaata acatcatatc
     6841 cttttttcat tgcacgaatg atataatcat gatgcgttcg atctactgac gtaataatga
     6901 cttcagccgg ccgtacgtca tccagtagtt gctcaaattg tgatggcata catgtcttta
     6961 cttttttctg tccatacttg ttcacaagta tccgatttgc ataatccatc cttgtttgag
     7021 atacatcaca aaaaccgact agttcacaag tttgatgata cgtagaggca attgcctcat
     7081 aaaaaaaacg cgctctccca ccaagtccga cttgtacata ttttttcttc atttaaagtc
     7141 attctccttt tcttttaagc aaaatactgt gacaaatggc agccctggat acagtaatgc
     7201 agtgagtaaa aaatcatgct gtatacacca gaacagtcca tacaaaaggc ataaatacca
     7261 cagaaacccc ttgacgtttt ttgacaacag ccagatattc cttttgatca aataaacaag
     7321 actatctgct ttatcttctt tgcagatatc aattagcgta ctaaaaaaac tatgggatac
     7381 aaaaagcaac agacacaata gaaaaggaat cagataccaa gctccaatct ttcccactaa
     7441 taaataccaa tcaactgcaa aaataatgac aaacagctga aacaacgtaa tgatgaaaca
     7501 catccgtttg atttttcctt tcctccaaca tacctttttt tctgccaagt aatggacaga
     7561 tagataataa gaaggataca tcatcaaaaa ataaatcaga tagacaacac gagcagacag
     7621 cactaatcct aaagtgaaca aacatcctag aactaaagcg aaaagagcat tactgataag
     7681 actggttaaa aaaatccgac agacatagta gttgagcttg taaagaaaca tctcttctat
     7741 tggctttttc atattcagcc cttcagaccg cttgtactga tcccctggac aagatattta
     7801 ttgaagaata agaaaatcag aaaaaccggt agcagcgaca acgtagacat cgcaaacata
     7861 ctcgcgtaag tcgtactaga tccagcgtct gcaaataatt tgatggcaat cgataccgtg
     7921 taagatctcg gcttgtttaa ataaatcaat ggtcccatga agtcgtccca tttccaataa
     7981 aactggatga tgatcgtcgt gatgatcgaa ggtttcagca aaggaaaaat aattttggta
     8041 aagacactat acttgctgca tccgtcaata atcgctgatt catctaactc tttggggatg
     8101 ctgaccatga attgcatgat ctggtaaatg aaaaatgctt gtccaaaaaa atgtggtaaa
     8161 atcagcggca catacgtccc aaccaaattc agccgattgt aaataataaa ctgcggaatc
     8221 aaaatcactt gtgcaggaat catcatcgtt actaacatga cgacgaacca gaatcttttt
     8281 cctttgaaat cgattctcga taatgcgtaa gcaatacaag tcgagctcag aactgtccct
     8341 atcgtcgaaa ctgcagagat gacaaacgaa ttcctaaaga aagtaaaaaa tgaaattcca
     8401 gcaaaccccg cccatccttt tgcgtaattt tcccattgaa aagtctctgg aatcaaattc
     8461 agcgaaccac tcataatctc ttgatccgtt ttaaaagaac ctgcgatcat ccataagacc
     8521 ggataaatca tgactagacc taatagcaaa ataaaaccgt attgaaacca tttcgttact
     8581 gtattattca tttcttcctc ctctcattca cacaacgacc catttttttg atgatttgaa
     8641 aatcagaaag gtgacagctc ccataatcaa cagcatgatc cacgaaatag cactagcata
     8701 ccccatagaa ttaaaagaaa aagcttggtt atacacataa agagcataaa agttcgtggc
     8761 atcattcgga ccaccttggg taatgataaa tgcctgcgta aaagtcataa acgccgcgat
     8821 tgtctgcata accaagttat acaaaatgat cggcgaaaga agaggtaacg tgatcttgta
     8881 aaacgtctgc catttgttcg ctccatcgat ctctgccgct tcataatacg agcctgggat
     8941 ctctttgata cctgcagcaa agatgatcat tgccgaaccg aattgccaag cagacatcaa
     9001 aacaagaggg atcatgacca gtttttgatc gctaaaccag gaaagcgcag gtgcgcctaa
     9061 tcgttccagg aaaatattca ctaacccgtt tttagaaaac aactcccgcc aaactagagc
     9121 gatagaaata ctgccaccga tcaaactagg cacataatac aaagaacgaa agaaagtcgt
     9181 tcctttgata ttcctcgtta aaagataagc aatcaataga ccaaagatca gtttcacagg
     9241 tacagatgca aatacataga gaaaagtgac tcggatggag ttcaaaaaac gggcatcact
     9301 cagcatcttt atataattat ccaagccgat ccatgagact ggatttccca aacgataatc
     9361 ggtgaacgaa taataaagtg acaagatcat cggtatcact gttatcaata gaaatcctag
     9421 gatgaatgga gaagcaaata cgtaaccgac cacattgtct tgatccaaga accgttttag
     9481 tttttctttt ttcatgcctt cctcctgctg ctatcctaga atgtttgacg caaactcata
     9541 aagactctct gctgcttctt ctgctgttac ttcttcataa atgacttttt caactaaaag
     9601 attgtattgg tcttgaattt ccggattcaa agcactatca aagacattca cttcgccgtt
     9661 gtccatatcg gaaatcattt ctaaataatc aaatgtcgct tgcaaagttg catcatctgc
     9721 acgagcgagc tgttctcgaa tattcgacat gattggtaca ccacgttctc cttttaaaat
     9781 ttcattggct tcttcactgt tttgaaagaa atcaataaac ttagcagctt cttctttatg
     9841 ggctgagctt tttgccatac tcagcatttg cgaagaacgt aaagggatac cagattctcc
     9901 atctgctttt ctgcgaggtg gattaatcaa ctgaatctcc atatcttcag gagcccctga
     9961 caatatttct gtcaactggt tacttgatag aaacaccatt gccgcttctc tatccctaac
    10021 cgcctgaaaa gacagatccg tcgtacttgc agctccacca cctggttctg gatgggcccc
    10081 tttgtctacc agatttttac gcagctggaa aaaatctgtt agatagtctg gattttcaaa
    10141 tcccaagctg ttagatagat cttcccgatt ataaaaattc aatcctttct caacttgtgg
    10201 tatttgaata atacagccag ctataaaatc ttcgaatctt gaaatagcat agattcctaa
    10261 ttcttcagtg atttgatagc tgatttgttc aaattcatcc catgtccaat ttgaagctgg
    10321 ttcagggata tttaattgtt caaatatatt tttattgtaa gcaatcgcaa acgaattcac
    10381 cccgttagac agtccaacta attgcccgtc gtaagtcgtc gttgctaaat aggattcatc
    10441 tgcattagaa atatcaatta tcccttgctc cacatattca tctaatggtt caatctgatt
    10501 gatgtattga ggaaattgat tgttcagttg gaaaatgtcc cagatatcat ctgatgctgc
    10561 tagtgtacct aattttgtgt aatatccttc ataatcataa aattcataat cgatcgtcac
    10621 atggggattt ttttcttcat aaagctcgat tacttttact gttgcatcgt gtcggacttg
    10681 cgaaccccac caagccatgt tcagcgtgat ttttttgtca tcttcttgcc cacaagccgt
    10741 caagaagaat aacataacac ttaaagctaa gatgattctc attcttttct tcattctctg
    10801 cacctctact tccattgtta tttttcaata tactgtattt ttatacagaa catatttatt
    10861 aaacgatctt tttcaagggg aataaaaacc aagacttgcc ttatcgttct gcctaggatg
    10921 aacaactcaa tactttcaag aaaaattaga tagtgctgat tcttctttca tcgctaaaaa
    10981 cacttcttgc ttcaatgatg ggaggataat tacgcaaaga aaaaaggata tcagacaact
    11041 gcccaatatc cttgacatag ctaaataagc atgcttcttc gtgtgcgctc ttccctaaaa
    11101 aacagaaaaa taactagtaa ttctgtatga aattaggtac aatatacacg tcgatgcaca
    11161 agcattgact atggcaactt gattggtcag ttcccgctga cttttcaagc cccgacaatt
    11221 tagctgctac taaattgtcg ggtgcctttt ttagttttta ttcgtttttc attctataga
    11281 aagcgcttca ataaatcaag acattttttt gttagaatgc taataataac aaaaggtttt
    11341 aactcttctt atgtacatta caggtaaaaa aacaaaaaaa tttctctttt ttttgaattc
    11401 tgaacaaata gtactggagt acaaaagacg aggaagagcc actatctgct cttcctcgtc
    11461 ttttgattct cacctgttat tcatgattct ttttctcagt ttcccgatat ttttccattt
    11521 tacgactaaa aagctctccg ctacttggtg gcgtatatgt gatggcattt gctcctgctt
    11581 gaatggtctc agcaatactt tcttccgttg gaccacctgt cgcaatgata ggaagttcag
    11641 gatatttttt acgaaaatgg cgtactgctt ctgcagtttc tttacctgca ctgatattga
    11701 taatcgaaat accagctgct aacttttcat ctatttctgt atatttcgac gttaccgtac
    11761 tgataactgg aatatcaact actcgacaaa cttcttttac tgtctctaaa ggcgtaggac
    11821 cgttcaaaac gacccctaac gaaccttgcg cttctgcgaa catgctcatg taggaagaac
    11881 gagcaccttg tgtcaaacca ccacctacac cggagaaaac tggaatgtca gctgcctcaa
    11941 taatgctttt agtaatcgct ggatgaggtg taaaaggata cacagcaatt actgcattcg
    12001 catttgtatt acgtatgatc gcaatatccg tagtaaagat gatcgaacgg atcaattttc
    12061 caaatatctt gatcccgctt gcttctaaaa tgatttccgg tactcttacg atatcttttc
    12121 tcaattccgt catgatttct ggcgtaaatt gttctgccat cagccacttc tcctttgcta
    12181 tctccggtca tactgattca attgatacgt ctcgatgacc tggatgattt tttgcgcata
    12241 accggggtct gtcgcataac ctgcatcttg caatgcttgt gcggcttcct gatagttggt
    12301 ggccgtaatc actttttcat acagcgcagg attccaatct actccttgga cgaacagttg
    12361 tgtatggtca tccatggact gttcccatga atcatacact ttgaagtctc cttggatagt
    12421 tatccattct tcgttaacaa attcctttgt ttccaggctt actttcttct gatccccata
    12481 agccttgatc ccgaaaagat tattgtattt gctagccaag gtactttttc cccaatttga
    12541 ttctaatata gcttgtccta aaatgatact aggaagcact ccataaccat cttgtagttc
    12601 ttgggcatgc ggaacaagcc gttcaataaa ttgctgatgg gattgcgctt cattttcttg
    12661 ctgattatca gtaaaaggag aagacagatt cttcaaggaa aaaacaaagg ctaagagtat
    12721 cactgctaca ccggcaacca ctgctggcca acggatattc ttgcgctttt gctttttcca
    12781 cttttttttc gccatgatca attcctactt ttcatttaat tcattcagat attcttctag
    12841 cgtcaattgg tgtttggtga tatactcagc gttttcttta ccgacataac gtaagtgcca
    12901 aggttcatat gtgatcttag ttatatcttc gtgtcctttt ggataacgaa cgataaatcc
    12961 atactgcgca gcattatctg cgatccattt agctccaggc tgatctccgt aacttgcatc
    13021 caatacagta gaaggataac tgttgtacca gttttgatcg acgacatcga ctgccagacc
    13081 tgtgtggtgt tcgctgtatc ctggctccgt aatcgtttct ttagtaatct ttgtcgcctc
    13141 ctcttctgat acaccttgac gactcatcac atcttggaca ttttgttcga aaacttgttg
    13201 ttgggatgat acagaccggt aagctgagac catcactaat ggaaatccag ctgcttcagc
    13261 agccttggca aatgcttcat attctggagc aatgcgtttg tcgatcaagt atccgttact
    13321 taatgatgcc aattgagtag actcatcaat ttctttttct aatttgtgat ctggaccaac
    13381 caaaactagc ttccaatcgt ctgttttaac atctggcaat tgtttggacg tacgatcttt
    13441 tgtttctttg tcctttacct tgctgctggt tgtttgactg ttcttttctt tactagcagt
    13501 tgttttggtg cttgttcgtt cgactgcttg attgccggct tgaacatgcg aatcatcatc
    13561 gctaaaaata acatagccca ttgctgcgat cataatcaca actgctccaa atcctaaaaa
    13621 tttattcact tgaaaaatcc tttcgttgtt cttcacgttc cccattcgcc tcatgaacgt
    13681 aagtttcttc cagattttca ttcacccaat cgagaagttc gattttttct ccttcgatct
    13741 gtttttgaac atctgctggc agacgaaaat tcaaaatatc atcatagccc cattcatcat
    13801 attgaatact tactttcaag tcaaggtatc taccagcctg ctgattattt ttcaaaggga
    13861 tcagctcgac ttttgctgct ttgctgctaa gccatttttg cgcgatgcgt gttttgattt
    13921 gcttgtactc tgcaacggca acgtttcgtt tttcgggaaa aataatcgtt tgacgcaaaa
    13981 tcttttgcgt tagcatccat tcataatcag tgaaaagatt ttttactttc tgcatcgctt
    14041 cagatggcag atttttctcg ccatctttcc atttttgcca ttgttctgga ctgatcagca
    14101 agtattcatc taaaaaattt ttttcagttt caaactgttc taataataca ctcataataa
    14161 gatcaatata tacttgatgc acgtttatcc cctcctttta actattctac ttaagttttg
    14221 atcaaaaagc acctcttaaa tcgctgcttt catttttttt aatgtttcaa gtcctctcct
    14281 ctttattctt cgtgattttt gttataataa tagacagaca agaaactcaa tccaactatg
    14341 aaggagcgtt ttcagatgaa aaaatatcaa tggggaatcg ttggtcttgg taccatcgca
    14401 catgagtttg ccgaaagctt caatcaagag acgagcgaac taacagcagt tgcttccaga
    14461 acttcagaaa aagcggaaaa cttcgctcac cgttacaata ttccaaaagc ttacggaagc
    14521 tatcaagaaa tgttagacga tgctgaaatc gacatcgtgt acattgctgt accaaataga
    14581 cagcatatcg accatatctt ggcagcattg gaagcaggca aacacgttct atgtgaaaaa
    14641 gccatcacga tgaataaaaa agaactggct gacgctatgc gcttagcaga agaaaagaat
    14701 ttgatcttag cagaagcgat gacaatcttc aacatgccac tttatcagca gttacgctca
    14761 ataatggata caggaaaact gggggcttta aaaatgatcc aagcaccttt cggcagttac
    14821 aaagaaccag accctaaaaa ccggttcttc aatccagaat tagctggagg agcactgttg
    14881 gatatcggta cgtatgctgt atctttcgct cgtttctttt tgagctctca acctgaagta
    14941 gttgcctcta caatggttcc ttttgaaaca ggcgtggacg aacaatcagt cactatcttg
    15001 cgtaacaaag aaaatgaact tgctgctgtc agcttgactt ttcaggcaaa aatgccaaaa
    15061 gtcggtatcg ttgcctttga gaacggttat gtgacgattg ctgattaccc gcgtgctgat
    15121 cgtgcggaga tcttatttac agatggtaca aaggaattca tcgaaagcgg gaatacatct
    15181 gaagcaatga attacgaaat aaagaatatg atacacatga ttgaaggtga cttgcccaat
    15241 cgctctctct tcttgacaaa agatgtcatc gaaatcttgg atcaaatgca agttctatgg
    15301 aaaaatatgt aattttaaaa ggttgtgaaa aagctgttct gcatcaagta ataagaacag
    15361 tcaaacaaaa atagctcctc ctatttttcg tttggctgga cttattaccg cagatgcaag
    15421 cttttgaaca ccgtttaagg aagaggtcgt gagcctgccg ttcagctccg agtcacaagg
    15481 agcaatttca aaaaacagct tctcatgttt gttgaatatt gtgacttgtg accgaggagt
    15541 tgacaggaga acaccgttta aagaagaggt tgtgaactca gctttttgac ctgaatatta
    15601 gctgaattca caacctctat ttttggattt tttgttggga gaattctgcc ttgatttcaa
    15661 taaaactttt aaaagactgc aaaaactgga acaattctgc tcgatcctcg aattcagggc
    15721 gactagtcgg cagaggcatt tgccgataca atacataaac ttcttcaata cgtgctaaaa
    15781 tttgtctgcc atcatttgac tctgaaaatg tttctgcagt ataaatcaat aaaccataga
    15841 tatgttttcc ataataagct ggttgctgga ttctctctag attttccagc atgtctttaa
    15901 tcacattggc ctgtgctctt ctcatagaga agcaagtttc gtagtatagc ggctgtctga
    15961 gccagtagtt ttcttgatgt tctctggcat cttcttggct ttcgcgaatg aatgtcagta
    16021 aacgttcgca tttgatctgc acatcttctt tattttctga taaaagaaat tctgccattt
    16081 gtctcaaaat atttcgaaat tctttttcga tctgtatttg gttttccttc agctgcttcg
    16141 tacgatctgg catgtaaaca tttgcaagca aagcaaatac taatccaatc gccattaatc
    16201 ccgcttcatt gccgatcagc tgccaagaca tgttttcctc cactaaataa tgagtgacca
    16261 aaaccgaatt tactacgatc ccttcggtta atttgaagcg agaggcaagc gggatgaaca
    16321 ggaataaaaa aagactgaag ccaaaaatag tatacccaac agcaaaaaaa ctgaacagtg
    16381 ctgttgccgt agctaatata aaggctgcga ttcgattcat gcccgtacgc aatgtagagc
    16441 gcttggtatt tcctacactt aataatgcaa tgatccctgc agctggccaa tacaacagcg
    16501 ataagctacc cgctgtgacc atcgaaaaga agacactgat cactgttttg actgttcgca
    16561 ttcctatacg catttacttc cccctttttt tattttaatt atacttgaat aatgaaaaac
    16621 tagctatcag acaaaagttt aggtatgata gtaaaaagac caaaaaggag aatctctatg
    16681 caatttggcc gttttcgact aggtatgcgt acgatcaaaa gtgccatagc tgttttttta
    16741 tgtatcttgt tttttcattt gactcaacga ggaatcccga tgattgctgc attatctgct
    16801 gttttttctt tgcgtcagga cttgactaca accgtttctt ttggaaagtc taggatcatc
    16861 ggcaatacat taggtggtac attagctatc atttattttt ttgtcaaaag ctattttcac
    16921 aatgattttt tggtagaatt gatcttgctt cctattctag ttattattgt gatcgtcgtg
    16981 tcagatggta ttaacaataa ttccggtatc atttccgcaa tcgctacgtt gttgctgatt
    17041 gcgttgagca tccctcaagg cgaatccgct ttgtatgcta tccaacgtgt actagatact
    17101 tttataggga cattcattgc aatcggtatc aatttctttc ttcgtcctcc tgaaacagaa
    17161 aagaaggaag aactatcaga agatttggtc gaactccaaa agaaagaacg attgctaaga
    17221 acaaatttac aagagataga agctaagatc caaaaacaaa agaaaaatag cgaggactaa
    17281 ttttcttttg caataaaata aaaaaatgga gagaagaact ttaaaaagtc ttcctccatt
    17341 tttgattgaa cggtgaagtg tactatttta ttcttcattc atcgagtttt gttctgcctc
    17401 ttttggcgct tcatacatat ttacttggct agtagtccca cgtgtcgaca aattctctac
    17461 gatttccttc aagtcaagtc ctgttgtcgc ttttagtgtt tcttgagtag aagaaagcaa
    17521 atttgtggca taatttgtca ctcggttcgc tccactggtt tctcctgaac tgcttcctgt
    17581 atcgacaaca gagatttttt cgatatttcc tagcggctgt gctgcttcgc gcatcaattg
    17641 cggtagcata tcgataacca tactcaagac agctgcttcg ccatattcct tgaaggcatt
    17701 ggcgatcttt tgttttgctt cggcttcggc ttttcctttt gctagtgctg cttcggcttc
    17761 tgcttgtcca gctaaacgtg tcttattggc ttccgcttct gccagtgctt ccacacggaa
    17821 tcgttctgct tcggcttcag tcacttcttt gactttttga gcttgtgctt cttgttcttt
    17881 agcgtaccga tcggcatctg cttttttctt cacttccgaa tcatattgct tttcacgacg
    17941 tgtgatttct ttttcttcca gttcgatttg tttttgacgt tctacgattt taatctgcat
    18001 ttcctgttcg attacttgtt gttgtgctcg ggcactttct aaattgtagg cttggtctgc
    18061 ttttgcttta gcaacatctt gttcttgttt gtaggttgct aatttcagtt ctttttcttt
    18121 taatgattct gcgatctctg tttgtcgctg taattcagct gcttgtgatt ctttttctgc
    18181 ttgagctttt ttgatacgcg tttcttttag agcttccgct tctgctatat ctgcatctct
    18241 tttgacttgg gcgattcttg gtttccctaa agagtcaaga taaccgtttt tgtctctgac
    18301 ctctttgata gtgaaagaaa cgatgatcaa ccccattttt gcaaggtcta cagaagcgac
    18361 ttcttgtacg ctttgactga acttatcgcg attttgatag atttcttcta cagtcataga
    18421 accaagaatc gagcgcaagt gtccttctaa tacttctctt gcttcatttt ccagttcttc
    18481 tcttgtcttg cctaaaaact gttctgctgc tgtagcaatc tcttctacag atgaaccgat
    18541 tttgatgatc gaagtaccat cacacatcac cggtacgcct tgttccgtat acacttcagg
    18601 ggtggagacg tccaatttac tcgataatag actgatccga ttcgaacgtt gaaaaactgg
    18661 caagacgaat gcgccacctc cacgcacaat tttgattttg ttattgcttt catcaatgtg
    18721 cacatttttg cttcctaaat aacttccact gatgatcaac gcttcatccg gttttgctgt
    18781 ctggtacttc gctacaaaga cgatcagcaa catcagtaaa atcaaagctg cgattgcgat
    18841 cgcgataaaa acaactggta tttccattta acacacgctc ctttaagctt ttatcatgct
    18901 ttcataaggc atgacataac agattctttc cttgatctca atgatcaata ctttcgttcc
    18961 ccgctcagct gtctgttctt gggggctgta aaaacaagct ggacgactaa tggaaccggt
    19021 aacacttttc aactgaattt ctcccatacc tcgtacaggg atcggtgtga tcacaacagc
    19081 tacttgtcct tccagagttt tttcagaaga cgacatcgtt gattcggcat gtttcatcgg
    19141 catcaatata tagaaattaa gcaaaaatac caacactatc gatatgcctc cactagcaat
    19201 aaataaaaat aaagatgatt gatctgttaa acgctcacct agaaaaccaa acaagcttgt
    19261 gaaagttaac caagggataa taagcatcgg atcaagcggg ccatcaaaat cgaatacatc
    19321 tccaaaaata atcaatagga ctgccaatcc tgcacaaatc agcaatgtat accaataaat
    19381 cgtctcaagt gcgattcccc ctatcatata cacgcctcct tccatttcta cgtctatcat
    19441 accaatgttt gaaaattctg tatagcttct tttaccgact cagtggtgtt ttttatagga
    19501 aggttgtgtt tatcgttgac aatttgttaa atttttgttt tcatgttaaa attttcacaa
    19561 taaattcttt cgaggtagcc tatgtttcct ttttttaaga aaaaaccatt aaagctccag
    19621 aacacgatca tccttgtcgt ttgtttctcc acattcgttt ctttgattgt ttctgccata
    19681 ttgatcagga attttattct ttcgatgaac cgatctagtg tgtcagataa aatctctagc
    19741 attgctaaaa tcgttgccaa tgataaactc atccaaaaaa agctgcagac tggtgaccca
    19801 acacatgcga ttcaaggaat aacaaatgaa atcatgattg catcgaattt agattttatc
    19861 gtggtcatgg accctgaagg cattcgatat tctcacgcag acccaagtta catcggtctt
    19921 cctttctcaa gtcatgaaga tgtgaaaaaa gtgattggag gacaagaatt tttctctgaa
    19981 aaagaaggaa tgttagggtt cggcttccgc tatttcgttc ctatttatta caatcaagag
    20041 attattggtg cagtttgtgt tggcttaacg aacaacacga ttgacaatca agtcaaagat
    20101 ggacaaaaaa tgattgtttt ttcattgatt atcggactta gcgtaggcat cataggcgcc
    20161 gtttttcttg cccaaaaaat gaaaaaagta ctgcttggac ttgaaccaca agaaatagca
    20221 gaacagttaa gtgaaaaaac gattatcgaa aatgaagtag atgaaggaat cttagccatc
    20281 tcttctgata aaactatcct cttgatcaat acacctgcaa aaaacatttt ctaccaaaca
    20341 gagcagctat tggatttcga agtaggaaaa aaaatcagtg ataatctata tgacgttttg
    20401 tttaaagaga cgattgagca tcaaacgacc gttcggactc aatccatgta tttaaatggg
    20461 atagaaacta tttctagcgt tacacctctt tttagcaatg accgtttttt aggagcagtc
    20521 gcaactttac gaaatcgatc agaagtaatg aaattaatgg aggagcttgg ggggacgaaa
    20581 caatatataa actccatgag agctcaaacc catgaattca tgaataaact tcatgtcatt
    20641 tctggtttga ttgatttgaa gaagtatgaa gaagtcaccc attttatcca gcagctaaat
    20701 caaaattata aaaaagagat tggccaagtc tcaagtctga tcaaagttcc tgcaattgcc
    20761 ggttttttat taggcaaaat aaacgaagcc aaagaacaat ctgttgaaat gctgttagaa
    20821 accgattctt ttatccctaa aatggagatg gatgactcca tccattcact tttgcaagtg
    20881 ttagggaact tacttgataa tgcaaaagaa gccgtgctac aaaaacatga aagaaacgga
    20941 caggtccgga ttcatttaaa ctatgacaca gaagctgaag tattcatcgt gaccgtctgc
    21001 gatgacggtg tcgggatatc agaagaaatc tcagaaaaaa tatttacgct aggtttttcg
    21061 acgaagggaa ttaatcgtgg gtttgggttg aatctcatcc attcaatcgt caaacgccac
    21121 ggtggatttt tagaattttc caaacaaaca aatggcggta caatcgtcta tctagaatta
    21181 ccaaaaaagg aagatcaaaa tgatgacaaa tgtcctgata atcgaagatg atccaatggt
    21241 tgcagaattg aatcgtactt ttgtggaaag catccctaat atgaacgtaa tcgaaagttt
    21301 cagaaatgta gaagaaggaa aaaaatattt cagacaaaaa aacgcagatc tgctgctgct
    21361 tgatgtatac atgcctggcg aaagtggtat ccatttttta tcttggctta gacagcaagg
    21421 aaatgatatc ccagtgattt tgatcactgc tgcagatgat atcgaaacca taaagaatgt
    21481 gatccgctac ggtgccttag attatttgat caaaccgttc actttgcaac gttttcagct
    21541 ggcgatcgaa aagtatcttg ctttctctca gacaatccaa acgactgaaa aagccgatca
    21601 gaaattgatc gatcaagtat tcaaccacac cactcccatt cacgaaatac catcattcat
    21661 cgatttgcct aaaggtctgt taaaactgac tttaaaaaaa ataagtgcat ttattctaaa
    21721 agaagatact attttttcaa caaaagaact ggctcaaaaa agctcactgt cacgtatatc
    21781 agtcaagaaa tatttgaatt ttttggtaga acaagatata ttgaacgaaa gaatcaaata
    21841 tttggaaatc ggccggccgc taacctgtta tgaattgaca aagaatgggc ggaaaaagct
    21901 cacagattac tgttgagtca tcgaattatc ccatacaaaa tagtccaagt atacagaagt
    21961 aacaactgtt tacttggact atttttaaac attttattga cgaatatcca tgttttctta
    22021 tcttaattga cgggctttag gaagagatac ctcatttttc gtttttccag tttctattat
    22081 ttcacgaaag ttctcgaaac ttgtcgaaat catatttgat aatgcctcat ctgtatttga
    22141 acctacatgc ggggttacaa gaactctagg gtacatttct actaattgct ggatagcagg
    22201 gtctggaatc gtctcccatg gcttgaagga tcggaaaaaa acctctgttt catttgcaaa
    22261 aacatcggtt gcaaaaccag ctaaatgatt gcttttcaaa gct
//
LOCUS       DAPBCF010000041        22219 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.042, whole genome shotgun sequence.
ACCESSION   DAPBCF010000041 DAPBCF010000000
VERSION     DAPBCF010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.042"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            171..515
                     /locus_tag="RD508_001983"
     CDS             171..515
                     /locus_tag="RD508_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDT7736537.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            516..935
                     /locus_tag="RD508_001984"
     CDS             516..935
                     /locus_tag="RD508_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDT7736538.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1027..1377)
                     /locus_tag="RD508_001985"
     CDS             complement(1027..1377)
                     /locus_tag="RD508_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736539.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1343..2674)
                     /locus_tag="RD508_001986"
     CDS             complement(1343..2674)
                     /locus_tag="RD508_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HDT7736540.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2930..3496
                     /locus_tag="RD508_001987"
     CDS             2930..3496
                     /locus_tag="RD508_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7736541.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3641..3728
                     /locus_tag="RD508_001988"
     tRNA            3641..3728
                     /locus_tag="RD508_001988"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3673..3675,aa:Ser,seq:cga)
     gene            4062..5036
                     /gene="bsh"
                     /locus_tag="RD508_001989"
     CDS             4062..5036
                     /gene="bsh"
                     /locus_tag="RD508_001989"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HDT7736542.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            5361..7256
                     /gene="asnB"
                     /locus_tag="RD508_001990"
     CDS             5361..7256
                     /gene="asnB"
                     /locus_tag="RD508_001990"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDT7736543.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(7451..7897)
                     /locus_tag="RD508_001991"
     CDS             complement(7451..7897)
                     /locus_tag="RD508_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HDT7736544.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8125..8274
                     /gene="rpmG"
                     /locus_tag="RD508_001992"
     CDS             8125..8274
                     /gene="rpmG"
                     /locus_tag="RD508_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDT7736545.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            8362..8880
                     /locus_tag="RD508_001993"
     CDS             8362..8880
                     /locus_tag="RD508_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDT7736546.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(8957..9913)
                     /locus_tag="RD508_001994"
     CDS             complement(8957..9913)
                     /locus_tag="RD508_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7736547.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10079..10885
                     /locus_tag="RD508_001995"
     CDS             10079..10885
                     /locus_tag="RD508_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7736548.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            10882..11871
                     /locus_tag="RD508_001996"
     CDS             10882..11871
                     /locus_tag="RD508_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDT7736549.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            11868..12872
                     /locus_tag="RD508_001997"
     CDS             11868..12872
                     /locus_tag="RD508_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDT7736550.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13004..13546
                     /locus_tag="RD508_001998"
     CDS             13004..13546
                     /locus_tag="RD508_001998"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDT7736551.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            13566..14264
                     /locus_tag="RD508_001999"
     CDS             13566..14264
                     /locus_tag="RD508_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HDT7736552.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            14285..14497
                     /locus_tag="RD508_002000"
     CDS             14285..14497
                     /locus_tag="RD508_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HDT7736553.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            14497..15459
                     /locus_tag="RD508_002001"
     CDS             14497..15459
                     /locus_tag="RD508_002001"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HDT7736554.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            15477..15872
                     /locus_tag="RD508_002002"
     CDS             15477..15872
                     /locus_tag="RD508_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDT7736555.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16035..16400
                     /locus_tag="RD508_002003"
     CDS             16035..16400
                     /locus_tag="RD508_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HDT7736556.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            16397..18208
                     /locus_tag="RD508_002004"
     CDS             16397..18208
                     /locus_tag="RD508_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HDT7736557.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(18270..18437)
                     /locus_tag="RD508_002005"
     CDS             complement(18270..18437)
                     /locus_tag="RD508_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HDT7736558.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            18685..19674
                     /gene="galE"
                     /locus_tag="RD508_002006"
     CDS             18685..19674
                     /gene="galE"
                     /locus_tag="RD508_002006"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDT7736559.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            19686..21170
                     /gene="galT"
                     /locus_tag="RD508_002007"
     CDS             19686..21170
                     /gene="galT"
                     /locus_tag="RD508_002007"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HDT7736560.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            21194..22174
                     /locus_tag="RD508_002008"
     CDS             21194..22174
                     /locus_tag="RD508_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7736561.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
BASE COUNT         7208 a         3806 c         4620 g         6585 t
ORIGIN      
        1 taaaaaaagc gttagcaact atgcttaaaa agcatatcga ctgaataaac taagcattgg
       61 acaggctgaa agactacatt taaaatgaaa tgcgaagaaa caatagaaaa taaagttgcc
      121 ttagaaccat agttgaatca cctaacagtc gtgaagggag aataagagaa atggcagaaa
      181 aacaaaccgc aggacgagat caattaggag attttgcacc aaaatttgca gaattgaatg
      241 atgatgtttt atttggacaa gtatggtcca gagaagaatt atctgctcat cagcgtagta
      301 tcatcaccat atctgcatta atttcaggag gaaattttga acaattgcca gctcatctga
      361 agattggcaa gcaaaatggc attactagtg aagaaatagc agaaatcatt acccatttag
      421 ctttttatgt aggatggcca aaagcttggt cagcttttag tttagcaaaa gaaatctatt
      481 tagaagaaaa tagcgaagat aagaaagagg cgtaaatgac gacaaaacac gaagaaatac
      541 acaatggcgt gatttttcca gcaggtgaaa aaaacgaagc ttacgctcaa gtatttaccg
      601 ggcaaagcta tctgaatatg ttagtgaatg atcccgaagt ttctgttggt gtaggtaatg
      661 taacttttga accaggttgt cgcaatcact ggcatgtcca taaagacggc tatcaaatct
      721 tacttgtgac cggaggagaa ggctggtatc aggaagaagg aaagccagca agacgattaa
      781 tggctggaga tgtcgtcgta acgcacaaag ggattaaaca ttggcatggt gcgacaaaag
      841 acagttggtt tgaacatttg gcgatcactg ctggtaattc agagttttta gaacctgtaa
      901 cagatgaagt gtatgaagga ttggaaaatc aataatgtca agcttgaaca gctcctgaaa
      961 gtagatttta atcgaacttt caggagctgc ttttttgatt cagtctttta taaatagaaa
     1021 atagggttaa taataggaat gagaagcacg tcgaaagatc ttaatattga taatcggctg
     1081 ggcatacatg atttccacgt catcaatcaa actacctaac agatgataat cttcccgatc
     1141 atgtcgggga ttacctaata gttcttgata atagatttcc atactagggt cccgaggatt
     1201 gttcagcaaa tcagcaagta catctaaatc ttctggctga gtttctgccg taccctgtat
     1261 ctctatgaaa agcccttcct cagcaaattc tactccaata cgtatttcag ttatttcatg
     1321 ggaatataaa taagtaagaa gctcatcgat gattcttttt gataattctt tttccaagtg
     1381 tctttttttc ctttctgaca gcggtaaagt tatctagtat cggtacaagg atacctgcaa
     1441 cgaaaccagt tgaaaaacca ctgttatata gatttagtcc tccgtgcaaa gtgctgacgt
     1501 tatggacaag agcaatatgt agtacaccag ctattacacc gtaaaaactg ccgtaaaaac
     1561 cgcttatggg cgcgagacct gtcccaaaca cagctgcaac aagcatgcca gtactggtga
     1621 tctcatgaaa agttccaaac aaagaagcaa taaatattcc gactagtatc ggaaaactgt
     1681 tttttaaatg acaaccaaaa gcactgaaac ccaccgcaga taaaatagca ccgatgacag
     1741 gtccatttaa ctgaccgcca accagcaaaa cataagaaga cagcatcaga ccaactaagc
     1801 ctatgttgat caaagtagca ccaataccag aattagcaat gaaatcagtt gtcaattttc
     1861 cagatgaatc gaaaatttct cgaatcccca aaagccgaaa ggaattataa tagaaaccaa
     1921 ttccgactgt cagcgaaaaa aagccaaaaa taatccaaat gagaggaaag tgatattcat
     1981 tgaaaaccaa tgtattttcg acgattgaat agctgaataa cctcaaaaca gcagtaaaag
     2041 tcatcgcaat caacccagag gtgaatccaa tattataaag tgtgaatcca cgatggaaaa
     2101 ctaaagtttg agcagctaag ggcggaagaa gtagaccaat tgctatgcca gctaaattcc
     2161 ccaataaaat acctatcagt aaaggaaaac gcataccaaa agtgatataa ctaacgaccg
     2221 gtgataatgc gctaccaaac agtccgatca tgatgtactg agaaaaaggt ttattgacaa
     2281 atacagcgta tagatacaca cctaaaatga ttgagataga attataaagg tttttgccaa
     2341 aaaaagagaa accggtaact gttagaatcg aagcaaataa gggaccgttt aaaatcacct
     2401 tgtgccgata agctaaaagc acagaaagta aggtcaaaat ccctacattt atgaatgcgc
     2461 ttccgaaacc gcctaaagca aaataatctg tcaaaagatt gcttggcgag gtaagaatag
     2521 ttagcaatcc actccaatta tcagtaggag tattagaaag caagccaata aaaagaaaaa
     2581 aaacacctgt aaaaccaaga taaaaatact ttcttttctg tgaaacgatt cgtttttgag
     2641 gatgaatata aataacgtca gtttcgtttt ccattacaca ccttcttttt cattttcttt
     2701 aactataact tgaaatgaaa gatttggaca actatcattt aggtcaaaac taaaaatgta
     2761 agggaaccca ttgaatttaa ccaaattttt ttaattttgc aaaaaaaagt taaagaagac
     2821 tgaaaaaaaa tttaaaatat aacgttttga gtaaaatgtt tgcaaaaaat gctaaaaata
     2881 gggtacaata aaacaacata tactgcagta aagaagtggg ggagttttaa tgagaagaaa
     2941 agtctatacc aaggatcaaa ttctaaaagc tgcttatgat gttgttgcaa aggaagggtt
     3001 taaaggattt actgcgagaa atattgctaa aaagatgggg atttcgacac agccgattta
     3061 tctggaattc aaaaacatgg aagatttaaa aaatacgttg ctggattcta tctttgaaca
     3121 actaaaagaa gatgttttcc ctattgaacg tactggtgat aaaatcattg atctcggttt
     3181 gaactatatc tactttgcaa aaaagcatca tagtctttac atggcattgt acattgatga
     3241 acatggggac ggaaagaaaa tgcatgattt ttcatacaat tatttccgtg aaatagttaa
     3301 agaagatgaa agatacaatc aattatcgga tgaatatgtc gatgctctgc atactggtac
     3361 atgggtagca gtgactggct tagcgtcatt gatgtcatca aacatcatgc atccaacaga
     3421 agaacaaatc attgcactga tcaaacggac aattgactcg attttagcat tagataatcc
     3481 tgaaataatc agatagtgtt ctatcagtat gaatttgatc ggtaagtccg ttggctgcaa
     3541 actgtcaatg gacttttttg ctaaaaaaag cgatttctgt tatttatcta ttagaaatag
     3601 gcttgacatt tcgtgaaaaa agtttaaaaa tagtacttac ggaaggttgg cagagtggta
     3661 atgcaccgga ctcgaaatcc ggcgaaccgg ctaataccgg cgcgcaggtt caaatcctgt
     3721 accttcctta tatcaacgat tagaggttgt gaagaagctg tcctgcatca agtaataaga
     3781 acggccaaac aaaaatagct tttcctattt tttcgtttga ttgggcttat taccgcagat
     3841 gcaagctttt gaacaccgtt tgttcggaat aaggggctgt gacaagactt ttgtcacagc
     3901 cccttattgt tgtactttta acctacaata ttttttgatt ccccctgagt actatttttt
     3961 ataaatgcta gtaaatcaat cttctttggc ctttttttga taaaaaaaat actagatgta
     4021 agataaaagt gtaaaaacga tttgttttag gacgggaaac gatgtgtacc gcaatcactt
     4081 atgcaacgaa agaccattat tttggaagga attttgatta tgagatgtct tataatgaag
     4141 tggtcactat tactccaaga aattatcgtt tcgattttag aaaggtaaaa aatttagata
     4201 aacattatgc aatgatagga atagcagctg gggtatccaa ctatccactc tattatgagg
     4261 ctacaaatga aaaagggttg agtatggcag gactgaattt tcctggcaat gctgattata
     4321 aagaattaca agaaggaaaa gataacgttg caccatttga gtttattcca tggatactag
     4381 ggcaatgctc aaccatagac gaagctaaag aattattggc tactatcaat ctagtcaata
     4441 tcgattttag tgaaaaacta cccttgtcac ctttacactg gttattagct gataaagaaa
     4501 aatcgatagt aattgaaagt atgaaagatg gacttcattt atatgataat cctgtcggtg
     4561 tgttgacaaa taatccgcca tttgattatc aattatttaa tctgaacaat tatcgctcgc
     4621 tatcaaatgg aacaccagaa aatcattttt caaaccagat cagcttgaat gtttatagtc
     4681 gtgggatggg aggattgggc ttacctggag atctctcttc tgtttctcga tttgtaaaag
     4741 ccacatttac taaaatgaat gctgcatcag gtgattcaga atctgaaagt atcagtcaat
     4801 tttttcatat actaggctca gtcgagcaac aaaaaggagt atgcgatact ggagaaagaa
     4861 aatacgaata tacgatttat tcttcttgct gtaacgttga taaagggatt tattattatc
     4921 gtacgtatga agacagtcaa attactgctg taaatatgaa taaagaagac ttggatcgtc
     4981 atgaattggt cagttatcca gtcataaaag agcaacagat aaactatgtc aattaattaa
     5041 tgaatagatc cgtttggtat catattttct gatacagtca taattagaca cgatctttag
     5101 gtcgtgtctt tttttgctgg tttttttgga aatagcatcc actaatattt ttttaacacg
     5161 aagagaataa ggtagcctca aaaaagaaaa catggtaaat tagatattgg gactttattt
     5221 tctgtaaaaa cagaaacttt catcttttgt tttcacgtga cgaaattgta agagagaaaa
     5281 tattcgtccg ctatttattc tatgataaga tgcatatgaa tgaaataaac agtaatttta
     5341 tattaggatg tgaaagttaa atgtgcggta ttgtaggttt tgttaacgac aaggacaaca
     5401 aaaaaacaat tattaataca atgatggatc gaatcgttca ccgtggacct aatagttcag
     5461 gagaatatat cgataaacat gttgctttag gattcagaag attaagtatt attgacttag
     5521 agggcggtac tcagcctatt tacaatgaag atcggacaaa gatcattatt tttaatggcg
     5581 aaatctataa ttaccagcct ttgagagaag aattgattgc agctggccac gtttttcaaa
     5641 cacatgcaga tacagaagtc cttttgcatg gttacgaaga atggggaaca gaattattgc
     5701 aaaagatccg cggaatgttt gcttttgcta tttgggataa tgaaaagaat gagttattcg
     5761 gtgcaagaga ccactttggg atcaaaccat attattatgc agaaatgaac ggaacattta
     5821 tgtttggttc agaaatcaaa agttttctgc ctcatcctga ttttaacaaa gaattgaaca
     5881 aagaagcgtt gaaaccttat atgactttcc aatattctcc attaaacggc gaaacattct
     5941 tcaaagatgt ctatcgtttg cctgaaggcc attattatac gtataaagat ggaaaaatag
     6001 acattcagca atattgggat gcagattttg aaacaaaaga aacgcattcc cgacaagaat
     6061 ggatcgaaaa aatcgacgaa accgttcaag cttctattga agcacatacg gtcagtgatg
     6121 tagaagttgg ttctttctta tccagcgggg ttgattccag ttatgtaacc tctgtattga
     6181 aaccagatca ttctttctca atcgggtttg atgataaaac ctataatgaa gcgattgaag
     6241 ccagaaaact aaccgaacta ttggacttag ataatacagc agcagtgatc gacggagaca
     6301 tgtcgttcaa agcattccct ttgatccagt atcacttaga tgaacctgat tcaaatcctt
     6361 cttgcgtacc tttgtacttt ttagcaaatc ttgcttcaca aagtgtgcgg gtagtccaat
     6421 ctggagaagg ggcggatgaa ctgtttgcgg gataccaaac gtatggattc catacgaatt
     6481 caaaattcat ccgtgtgatt gctcaaggat tgaaaaaatt accaaaagga acacgctata
     6541 atttaggacg taaaatcgga aaaatgaaaa atttccatgg acggatccat ttatatgaat
     6601 cacttgctcc tgcaaaagaa tattttatcg gtcatgctcg agtgttcgaa gaatcagaag
     6661 catcagaagt gttaacacca aaatatcaaa cagcaccatc tgtggatgaa atcatgactg
     6721 ttcattacga gaaaacagaa ggaatcaaag atgaagtcaa taagatgcaa tatgtcgatc
     6781 ttcatcaatg gatgccaaaa gatatcttgt taaaggcaga taaactttct atggcaagtt
     6841 ctttggaagt ccgagtacct ttattggata tcgaagtcat gaaattggct caacaaatac
     6901 caagtaagtt tttattgaat caaaacaaca caaaagatat tttcagacaa gctgcgaaca
     6961 aacatcttcc ggaagaatgg tcgaatcgtg tgaaattagg attccctgtg ccaatcaaag
     7021 cttggttgaa agaagaacac ggctacgaac aagtcaaagc attattcgaa gcagattttg
     7081 caaaagaatt ttttgatcaa gaaaaaatca tgaagttgct agatgaccat cacgaaggac
     7141 gtaaagaaga gcaaagaaaa atctggacaa tcttcagttt cttgacatgg tataaagtct
     7201 actttgtaga tgaaacgatt ccgcaagcag aagcaatcga ctatgtgact gtttgatgaa
     7261 aatcaaatat caataaaaaa gaggttttct cctaccgttt aacactgagt gataagaaac
     7321 aatttcaaaa aacagctctt cccgttttat agatattatg acttatggtt cggagttggc
     7381 agaggaacac cattgtttcg aacataaggg ggttgtgaca cgattttcgt cacaacccct
     7441 ttacatatgt tcaataatcg atttcttttt cttttgtccc atctttttta taaatgaaca
     7501 aagttgattc tttgttttgt gctacttgct ttcctttttc gattgcttct ttttttgtat
     7561 caaaatggtt gcttgccttt tttgcccctt tagatttcac gatccattgt tcttcctcat
     7621 attctacgat cacatctgaa tcaagcagtt ttccagcacg aggattcgta tcgtgttcat
     7681 ccgtcttgct tggatttttt tctttttcga aagttcgttt ttctgattca ctagcatctt
     7741 cataccattt ttttgcttga tcaatggcaa ttgggatcgc acggttatca gggtaccctt
     7801 catctaataa tgcatttgcg atgtcgattg ctttttttct tgtcaattta tctaagtttt
     7861 tcattgatgc aggaaagtcc ttcatgttcc atggcatatt agtatccccc tttattaaaa
     7921 aacataatct atataaacaa gtgtaagggt atttatacaa aaagaaaaag attttgtttg
     7981 agaagtaaaa ccgttgtatt tatcgtcaag tagttttact taacaaaatc gtgaaaaaca
     8041 ctagcaatct agaaaaaatc atggtaagat aatcaagtct gagagtcatc ttagaggatt
     8101 cttgtaaaaa tgggagggaa aaacatgcgc gtaaacatca ctttagagtg tacttcttgt
     8161 aaagaacgta actatctaac aagcaaaaac aaacgtaaca atcctgatcg tttggaaaaa
     8221 caaaaatatt gcccacgcga acgcaaagtt actttgcacc gtgaaacaaa ataatgtttt
     8281 taaagttctc aattccttgc tggtcaaaga attgagactt tttttatctc aaaacatcta
     8341 aaatcataag gagcggataa tatgtttatt tccatgtggg cacaagataa aaatggtctg
     8401 atcggcaaaa atggtttgtt accatggcga ttgccaaatg atatgcgttt ctttcgcgaa
     8461 cacacaatgg atcgaatttt agtgatggga agaaagacct atgaaggaat gggggatctt
     8521 tcacttcctt atcgccatat catcgtgttg acaacgcaac caaattttcg cacgaaagaa
     8581 aatgcggaag taatgcattc gatcgatgaa cttttgtcgt atagtcaaac gatctcagaa
     8641 gatatctatg tttcgggtgg tagtcggatt tttcaagaac ttcttcctta cactggtcgg
     8701 atctggcgaa cattgatcga tagcacgttt gaaggcgata cgtatattgg gaatattgat
     8761 ttttcagact tcgcccttat agaggagtat gaggggataa cggatcaaga aaatctatat
     8821 gcccatcgtt ttcaaaaatg ggaaagagta aaaaataggg ttgcttcaaa agaagaataa
     8881 aatctatgcg tctagtttgt taataagaaa aaaagcatct cacgactaat cgtgaagatg
     8941 ctttttttag ttaaaatcaa tttagttttt ctttgatatc attgaccatt tcctgactgg
     9001 caataggtcc gttatatagc caactagatt caggtccgaa ttgcagtaca tgattgtctg
     9061 tcactgcttt tagattcttc cagcttggtt cattgaacat ggcagcatct ttgtcactgt
     9121 tcacaaggat gatgtagtca gcatctaatt cagctagctt ttcagaggaa acagcagacc
     9181 agtcagaagt ggcttttttg gagacctctt ccactagatc aggaacacca aattccagat
     9241 cgtcgtatac gattcttcca cttgaccgat ttttgctgac cataaaggct gagttgttgg
     9301 tcacccacaa cactgcagct gtcttgttct cgattttatc tgctagttct tctcgagttt
     9361 tcttgatgga tttttgataa tcggaaatga ttttttctgc ctctttttct tttgccaaag
     9421 ctttgccgac atcttttagt tgttcttccc atgtgacatc tgttccgttt tttacaacat
     9481 aagttggcgc gattttgcta tattgttcgt atttcccgcc ttcgacagta gcggaagaag
     9541 aaatcaacag caaatcaggc tcaaagctta acactttctc ataaggaagg tcataagaaa
     9601 tcgttgggac atcctttaaa tcatcttgca gataatcttg aatggaacca ctgccaacag
     9661 tccactgggc gataggtttt tcccctagtg caatcagata gtcttctaag taactgccga
     9721 tgatccgttt gggcgcgttt ggaatctcta ctttatgtcc aagtgtatct gtgactgtat
     9781 gagtactatt ggatgaagtc gtcgaattgg cagttgtagc tgtttcttta tctgaagagg
     9841 gggagcaagc gctcagtact ccagccagca gcaatatgct agataatgtg aatacttttg
     9901 tttttaattt catttctttc ctcctaacat aattgagaat ctttctcatt ggttattatt
     9961 cctgatattt cgaacgctgt caaccgcttc atttggctat agatatgaaa gtagcgcttg
    10021 acgaaatgtt gaaacagcgt cataattgag aatgattttc agcgaaagga tgggtgaaat
    10081 gacgagatta agagcagctg acattgcagc cggctacgaa aacaaaaaaa tcattgaaaa
    10141 catgtctgtt acgattcctg aagggaaaat cactagtttg attgggccaa atggaagtgg
    10201 aaaatctact ttattgaaaa gttttacccg tatactacct gtgaaatcag gaaagatcat
    10261 tgtcaataac tctgatatct ctacatacag ttcaaaagaa cttgcaaaaa aaattgcatt
    10321 attagcacaa actagtgaac accctacagg tatgacagta gaagaagtag tatcttacgg
    10381 acgataccct tatcaaaaac tgttcagtgg catggacacg caagatcatg aagcaattga
    10441 gtgggcgttg gatgctacag gtctagctgg atttcgtatg cgggatatcg caacgctgtc
    10501 tggtggacaa acccagcgtg tctggatcgc tatggcgctt gctcaggaaa cagatatctt
    10561 gatcttggat gaaccgacaa catttttaga tccggcacac caattagaga tcctacagtt
    10621 attgactgaa atcaatcaaa tgaaacaaac aacgatcttg atgtcgattc atgacattaa
    10681 tcatgcttca cgtttttcag attatttatt agcaatgaaa aacggtaagt tgatcacaga
    10741 aggtacacct gaagaagtga tcacaaaaga gtgtatgaaa aaaatatttg agattgatgc
    10801 aacgattgtc acgcttccaa gaacaaataa accagttttt ctaacctatg atttgttgcc
    10861 aaaagagcag gaggatcaat tatgaggact atgaagaaaa atagactcct gcttttggtc
    10921 tgttttgttc ttttgattat tttttttgtt gctctttcaa atggcgcagc gactgtggga
    10981 aaagcagatt tttggcaggc gttgtttgat tttgatagat caaaacaaag tcaccaaatc
    11041 atacgaaata ttcgtttgcc tcgtgtggcg ggagcatttc ttgtagggag ttgttttgca
    11101 ttgagcggtg cattgatgca aggagtgaca agaaatcctt tagcagattc aggcttacta
    11161 ggaatcaacg cgggtgcttc gttggcaatg gcccttagtt ttgctttttg gcctaaagct
    11221 tctgattttt ctgtgtttct aatgtcattg gcaggttctt ttgctgtaac tttgctcgta
    11281 tttggttttt tgcagttttc gaaaatgggc atgaatcctt tacagctgat tttagctggc
    11341 gtagctatta gttctttttt tactgctatc agccaagcac ttacccaatt ctttaatctg
    11401 cagcaggatc ttgctttttg gtttgtaggc ggagctgcca atatcacatg gaaacaatta
    11461 gcagtattgt ttcctttata tatacttgct gttttggttt ctttttcatt aggaaaagca
    11521 atatctttga ttcatttgag tgaaacacat gcattagctc ttggaagtca tcctaaacga
    11581 acgcggttga ttgttttctg tctagttgca gtgttagcag ccattgccgt ttcgttagtc
    11641 ggacctgttt catttattgg gctgttggtt ccgccagttg ttcgcggaat ggttggaacg
    11701 gactatcgtt atgttctacc tgtctctttt ttagttggcg gtggattggt tatgttggcg
    11761 gattttacag cgaggatgat caatccccct tttgaaacac cttttggatt agtcattgca
    11821 ttgattggcg ttccgttttt actgatacaa gtaaggaggg aacaacggtg aaaaaaatat
    11881 attggacgtt ctatttcttg ctttttgtac ttgtcatcct gtctataggt agtttaatga
    11941 ttggtacgcc ttttatttac ctggatcagc tttttgccac gttcataggg aaagaatcat
    12001 cttctttggc gctgattgtt agagaatttc gagttcctcg attactgatc agtttattag
    12061 caggagcttg tcttggcgtt tctggttata tcttgcaagg agtaacaaga aatgaattgg
    12121 cagattctag tatattgggc attaatgccg gagcaggatt tttagtgatg ctttatttag
    12181 gtttcttttc gcactattcg ctgccgtttc tattgctagt tgtagccttt ctaggtggtg
    12241 ttttagctgc ttgctgtgtc tatcttgcgg cctatgatcg aaatggcttt ttgggtatga
    12301 atcgaatctt attgtccggt attgccgtta atgccggcct ttctgcatta acattgctat
    12361 gcacgatcca attatctaag gaaaattatg gatttgtgaa tgcatggtta gcgggatcaa
    12421 tctggggtgc gagctggcct tatgtttggg cattgcttcc atgggcggtt atcttaattc
    12481 cgctaggagg actttatgca cagaggattg tattgctatc atttggtcaa gaacgcgcgc
    12541 aaggattagg ccttaacgtg gctaaaagtc aaaaaatcct tttgttgtta gctgttgctt
    12601 tggcaagcgg tagtgtagcg gtgacaggta gtttatcttt tgtaggacta ctagctcctc
    12661 atgctgcgaa gctagtcgta cgtaaagaaa ataactggac ctttgttctg agcggtttgt
    12721 tcggttccat ttttctgctt agtgcagata tggttgctag agtgattcta ctaagtgggg
    12781 aagtacctac aggaattttg attgcccttt ttggtgcgcc atattttctg tatgcacttt
    12841 ttatcagaca aaaacacgcg ctgaacagtt gaaattcatt aaaaaaggaa ggccaatcat
    12901 ttctaggtct tctttttatt ctatttatgc atttatttga aagttcgatt gctatttttc
    12961 tttttttcct ataccatttt atgagagaag gaagggtgag tttttggacc aattgaaagt
    13021 aagattacgc cggaaaggaa tcgaaaagct gaaaaatctg gccaaaagtg gcaagaaaaa
    13081 ggaaaaagaa cagcgaatct ataaacagct attcgccagc gagtactgga agtcagcaaa
    13141 agtgataggg acgactttat cgaatgaatt tgaactggat acacagccgg ttatccaacg
    13201 agcagaaaaa gaacaaaaga aaatagttgt acctaaaact ttgccgaaac gtcagatggc
    13261 gttttatgaa atggatgaac agtccgttct tgtacgttcg agttttggtg ttcttgagcc
    13321 acaatcagag aagctctatt tgccggagat gatcgatctc ctcattgtac caggtattat
    13381 ctacaataga gccggttatc gaatcggttt tggcggtggt tattacgacc ggtatttaaa
    13441 taattttcat aaaaaaacat gtagccttgt ttttcgtgaa caattgaatg aacaatggca
    13501 accggagagc tttgatcaga agatccaaca attgtttatt gactaaaatg aaatgggagg
    13561 ttttcatgaa ttatcaacag caaataaaat tgcgtgcatg gttaagacga ccgttatgga
    13621 cctatgcttt tttagggata cagacagcgg tcttcctcat gatggaatta tttccgcgac
    13681 ttgagatccc ttattatgcc ggaatgtatg gtccttatct tgttcacttc aatgaatggt
    13741 ggcgtttagt gacaccaatc ttcatccatt ttggactgat gcatttcgta atgaactcac
    13801 tgatactgta ttttatgggg cagcaaatcg aggcaatcta tggccattgg cgttttttct
    13861 tgatttatat gttcagcggg ataatgggaa atacagcaag ctttgctttt aacgaagcga
    13921 atgttctgtc tggtggtgca agtacttcga tattcggttt gttcggtgcg ttgtttatct
    13981 tagggtttca ttttaaacat aacccagcga tccagcagct agtcagacat tttcttttat
    14041 ttattgtgtt gacatttgtt tttggtcttc tggatacctc tgtagatgtt tggggacatg
    14101 tcggtgggct aattggcgga ttagtgttag ggaatgtttt gggtctaccg aaacaacaga
    14161 caagctattc gatacaccaa aggattcttt ctacactagt ttttgtattt ctttttgtaa
    14221 tatgtatttt actgggttta aaaaaatatg gtttacttgt ataatatgaa ggaagtgctt
    14281 aaagatggag agcttatatg atgtacagca gctgttcaaa aaatttggca tctttatcta
    14341 tgtgggtgca cgcatctatg acattgaatt aatgactatc gaattgcgta atctgtatga
    14401 tagccgtttg attgatcatg atacatacat gacagcgtgg cgcatattaa aaagagagca
    14461 ccgaattgaa gaaagccgaa agaaaggaaa tttgtaatgg acaagaagat tattgggatt
    14521 gatttaggtg gaacaacagc aaaatttgca attttaacac cagaaggaga gattcagcaa
    14581 aaatggagca tcgataccaa tattttggat gatggtaagc atatcgttcc tgaaatcatt
    14641 gaatcaatca atcatcgttt gaatttatat aatatgaaag ccgaagactt tatcggaatc
    14701 ggcatgggta ccccaggaag cgtggacagc gaagctggaa cggttattgg tgcgtataac
    14761 ttaaactgga cagaagttca atttgtgaaa aaactgatcg aggcaggaac aggaatcaaa
    14821 ttcgctatcg ataatgacgc gaatgttgct gctttaggtg aacgatggaa aggtgctgga
    14881 gaaaacgatc cagacgttgt attcgttact ctaggaacag gtgttggcgg aggtatcgtt
    14941 gctggcggaa atttgattca cggcgtgagc ggagctggag gagaaatcgg acatatcact
    15001 gtggatcctg aagggttcga atgtacttgc ggtaaacgcg gatgtttaga aactgtatct
    15061 agcgctacag gtgtggtacg cctaggtcgt ttcttggcag aagaatacgc aggggattca
    15121 aaactgaaag caatgctaga caacggagaa gaagtaacaa gtaaagatat ctttgaaatg
    15181 gctcaagaag acgatccgtt tgcattgatg gttgttgatc gcgtatgctt ctacttaggt
    15241 ttagcttgcg gaaacttggg gaatacatta aatccgtcaa gtatcgtgtt aggtggagga
    15301 gtatcggcag caggagaatt tttacgtagc cgtgtagaga aatattttaa agaatttact
    15361 ttcccgcaag taagagaatc aacaaaaatc aaattagcag agcttggtaa tgaagctggt
    15421 gtcattggtg ctgcctcatt agccttgaaa tttgcttaaa aaaacggagg cattacatgg
    15481 ttttatgggt aattaatatc attttgctat tgattgtgct tgcaatcatc ctttgggaag
    15541 tctatctacg agtaatggcc aaacgttcag caacgacttt gacagaagaa gaatttcgag
    15601 aaggaatgag aaaagcacaa gtaatcgatg ttcgcgaaaa agatgtgttt gatgctgggc
    15661 atattttagg tgcaagaaac atcccttaca ctgttttgaa agattcatta ggatctattc
    15721 gaaaagacca gcctgtctat atttacgatc aaaagaaaag tttgagcatc cgtacagcaa
    15781 ataaattacg taaagcaggt tatcaagaga tttatttact taagggtgga tatgacggat
    15841 ggtctggaaa aatcaaaagt aaaaaagtat aaaacagatg attgtatgac agctttaaaa
    15901 accgaatcaa tcattagatt ttgaccaaga tcacatgaac ggcgcaatgg atagttgtgc
    15961 cgttcatttt ttttattttg tgctattatc tacatatata agctaagcga aaaggtagaa
    16021 agaaggaaac aactatgatc aaattaaaac gtgtttacct tgatgctgaa aaagaggatg
    16081 gctatagaat actcgtggat agattctggc cacgaggaat ttcaaaagaa aaagcgcagt
    16141 tagatctgtg gttgaaagaa attgcaccta gtaatgaagc acgcaaaact tttgaccatg
    16201 taccagaacg atttgcttca tttgcaaaga aataccagca agaattgatt ttcgaagaag
    16261 aaaagaagca agctattttt aaactcagtc aacttatgaa agaacatcca gtcattactt
    16321 ttgtttatgg tgcaaaaaat gaacatcaga accatgctgt tttattgaaa aaatttatcg
    16381 aaatggaggc atgcaaatga aaatagggat cattggtgcc ggacctagag gattaagtgt
    16441 agcagaaagg attctccata ataatcagga cagacattct cttgaacttt ttcttttcga
    16501 tcccaatggt cctggaggtc gagtttggcg gttgaatcag ccaccggagt tattaatgaa
    16561 ttctgtttct caacaagtga cgctttttac agatgaaaca ttgtccagtg gaggattggt
    16621 aacacaggga cccaacttgt ttcaatggag taaaggacct gctacagatt atatcgaaca
    16681 gacggtaacc aaaaataagc aactaattat agaagaaatc aatcgtctgg aaaaagatca
    16741 gcaatctact cgatgtttat acggactcta tcaacgctgg tttttctcaa agttgcaaga
    16801 agaatttcca gcttctattc agtttgttta ttctttagta aaaaaagtaa gcaaaagaaa
    16861 agatggttat cttttacaga cagatcagca aagctattct atcgatcagc ttgttttagc
    16921 aagcggtcac tgggaaaatg atgagacaga agaagaaaga gtgtgggtag actacgcaaa
    16981 gaaaaatgtt ttactgtatc agcttccttc taatcctgca gatgtagatc tttcgaagat
    17041 accgcctaaa gaaaatgtct ttttaagagg tctaggctta agtttttttg attatgtcgg
    17101 attgtttaca gtatcaagag gagggcgctt cgagaacgaa aagggaaaac tggtctatca
    17161 tccatcaggc aaggaaccga ttgtatacag tggatcaaga agggggctcc cttattaccc
    17221 tcgaggaaga aatcaaaagc aaggcggagc aatggcatgg ccacggttac taacaaaaga
    17281 aaacctggag caatggcatc agtcgggatt tttgactggc gaaacatttt ttgactatct
    17341 gaaaaaagac gttgagttgt tttattacaa gaaaatcatc gaagaatatc acttgccgat
    17401 tccaaagaaa aattttgagc atgattttct ctccctctct tcagaggagt gtctcggaaa
    17461 gcatccagca ctaatccctt atagatggga ttggtcgtat ttagaaactc ctcttgccta
    17521 tcagaatgag cccttttcag aagctagccg aatatttatt gaagggcaga taaaagaagc
    17581 ggaaaaaggc aattgcacag gagcatttgc ttcaacattt gatgcattaa aagactggcg
    17641 tgatccaatc cggcaggcta ttgaatggca cgttttttct gctaaggaat acaaagaaat
    17701 actatgggga tggtttactc atctaaatag ctttttaacg atcggtccgc caatcattcg
    17761 gacgaaagaa ttagcagcac tgatagatgc gggtattttt catttgatcg aaccgccatt
    17821 tgatattcag caaaagcaca accgctatgt tatttctcta caagataaag aaatcagcag
    17881 tcgctatttg attgaagctc gattgccaca aacaagcttt tctcgttcaa gtaatcctgt
    17941 cataaaaaat ttgaaggaaa acaaacttgt tcgccctttt tcattttcag ataatacagg
    18001 aagttatcat tcagaagcta tagatgttga gcgaggtacg aatcgcgtga ttgatgcttc
    18061 aggggaaatc cagtctgact tttattgcta tggaatacct gttgaaggtg tggattggct
    18121 aactgcagca gtagctagac cttatacaga tccatggaat ctgagacagg cagataaaat
    18181 agcacaactt atattgactg acaaataaaa atacgcatga tgacttatct gttttttaga
    18241 aagtcttcat gcgtattttt aaataattat taacgagaaa cgcgtttacg cattgctttt
    18301 ttacggtttt cttcgatcat tgcttctttt tcgtcaattg gatcgatcac tgtttttttc
    18361 acagaagcaa ccaaaccagc aacggcagcg gctgttgcca gacttcctac taatattcca
    18421 gatacaaatt ttttcattga atccacctca tttattattt gttatatcta ttatggaaca
    18481 aaagagaaaa aaaggctagt tttacgtttg tttgtaaacc tttgcaaaaa atccttgaaa
    18541 atgtttacta aatgttttat tataaattta ccatatgaat ttacgaaatt ttactttgtt
    18601 tgttttcacc ataaaagtaa acttcgtttt ttaaattata tagaatcaac aaacacaatt
    18661 ttactaatca aaggagtgtt ttttatgaca attttagtac taggcggagc cggttatatc
    18721 ggttcgcacg ctgtagacca gctagttcaa aaggggtatc aagtagctgt ggtagataat
    18781 ttgctcacag gtcacaaaca agcagtacat ccagatgctc atttttatga aggagacatc
    18841 cgggataaag aatttctacg ttccgtattt gaaaaggaac cgattgaagg agtaatccat
    18901 tttgctgcaa gctctttagt aggagaatct gtcgaaaaac cattgatgta tttcaacaac
    18961 aacgtatacg gtatgcaaat cttacttgaa gtcatgcacg agttcaacgt gaataaaatc
    19021 gtattctctt ctactgcagc aacttatgga gagccgaaag agtctccaat cacagaagat
    19081 acaccagcta atcctaaaaa tccgtatggt gaaagtaaat tgatgatgga aaaaatgatg
    19141 aagtggtgtg accaagcata tggcatgcgc tatgtcgctt tgcgctactt caatgtagcc
    19201 ggagcaaaag cagatgcatc tatcggagaa gatcatacac cagaaacgca tcttgtccca
    19261 atcattttac aagtagctct tggtcaaaga aaagccttgg ctgtttatgg agacgattat
    19321 gatacaccag atggaacatg tatcagagat tatgttcaag tagaagattt gattgctgca
    19381 catattttag ctttggaata cttgaaagaa ggaaatgaaa gcaacttctt caatttaggc
    19441 agcagcaaag gatactcagt caaggaaatg ctagaagcag ctagagaagt gacaggaaaa
    19501 gaaattccag cagaaatagc accaagaaga gctggagatc ctagccgatt agtcgcttca
    19561 agtgaaaaag cgagagagat tctgggctgg aaacctgaat acacagatat caaagcgatt
    19621 atcaaaacag catgggattg gcatgtcagc catccaaatg gttatgaaga ataggggaat
    19681 gagatatgtc aatcagtcaa acgatttgtg attttgccac acttgcgatc gaagctggcg
    19741 gatggatgga aatggaccgc ttatatttac agaatcgtct tttagggatg gtaggagaag
    19801 atgctctaga aagcattgaa gtaagaccag ttaaggaaga atctgtagac ttattggatc
    19861 agcttgtcgc taaggcaaga gaaaatggtg ttctttcaga attgccagca gaacaagaga
    19921 tttttgaagc gcaattaatg gattttctca caccgccacc ttcagtcgtc aatgcattct
    19981 ttgcacagca ctattcgaaa agcccagagg aagcaactga gtatttcttt aatttaagta
    20041 agaaaaatga ctacatcaaa acaagagcca tcgcaaaaaa catcaaattt ccggcagagt
    20101 cggagtatgg tgaactggaa atcacaatca atttatctaa gccagaaaaa gatccaaaac
    20161 aaatcgcagc agaacgcgag gcggtaaaag tagactatcc tacctgcatg ctttgcatgg
    20221 aaaacgaagg atatagaggt cgcttgaact atccagcccg caccaatcac cggattattc
    20281 gaatgaatct agacggtgaa agctggggat tccaatattc cccttatgct tattacaatg
    20341 aacattcgat cattttatca gaacaacacc gcccgatgaa aatcacaaag gaaacatttg
    20401 ctagactgct tcggattact gaagtcttgc ctcattactt tgttggttcg aatgctgact
    20461 taccaattgt tggaggatcg attctttctc atgatcatta tcaggcagga cgtcatgaat
    20521 ttcctatggc aaaagcaccg atagaaaaac ttatcaaact agaagattat ccgcaagtca
    20581 tcgcaggagt cgtgaaatgg ccgatgtctg tgatccgttt gcaatcaaca gagaaaaact
    20641 tgcttattga agcagctaac tcagtattgg aaaaatggaa agcatattcg gatgaaacag
    20701 tatctatcag agctttttca gcagatggta caccacacca tacgattacg ccaattgcac
    20761 gaagaaggga caattacttt gagttggacc ttgtccttcg agacaacaat gtttcagaag
    20821 aacatcctga tgggattttt catccacata aagatgtcca acatatcaaa aaggagaaca
    20881 ttgggttgat cgaagtaatg gggcttgctg ttttaccacc tcgtttgaaa ccagaactag
    20941 tagaagtaga gcatttctta ttaggagaag aaaaccagat ggctgaatat catcgtccgt
    21001 gggcagaaca attaaaaaaa gaacatcctg atttgacgaa agatacggtc accgatgtcg
    21061 tacaaaaatc tgtaggtcag gtttttgcac gtgtactgga agacgctgga gtattcaagc
    21121 gagatgaaaa aggacaggca gcgtttgaac gatttactgc gattttataa acgtaaaaaa
    21181 ggaggagaga caaatggcaa caattaaaga cattgcgcag ttggcaggag tttctcctgc
    21241 tactgtttca agagttctca actatgatcc tgatctttcc gttggcttag ccacaaagca
    21301 aaaaattttt gaagcagcag aacgcttaaa ttatacgaaa catcgtaaaa atgcagcaaa
    21361 tactaagcaa acgcttcgcc tgatccagtg gtacgacgat acggaagagc ttgaagatct
    21421 ttattattta tctattcgcc taggaatcga aaaaaaggca gaagaagcaa acgttacttt
    21481 attgaaagaa acgtgggatt ccattagtga tcttccggca gatggaacga tcgcactagg
    21541 aaaattcgac gaagctcagt tattagaaat gaaaggatcc caaaatgcct tgcttttggt
    21601 agattctgac ggcacttctc aaggaatcga ctctctagtt gtcgacttta agtcaagtgt
    21661 tcaaaaagtc attgaacact ttgtctccca taaagcgcaa catatcgcta tgcttgctgg
    21721 aacagaatat acgaagaaaa accatcagcg gctaaaagat cccagaatta tggcatttca
    21781 acaagttttg gcagaaaaag gctacgacga aggtccaatt atcgaagcag atttttctgt
    21841 cgagtcagga tatcaagcag tgaagcagta tttaaaaacg aatccgcatg ttcctgatgc
    21901 gctttttgca gctaatgatg cattagcgat tggcgcactg aaagcgattc aagaaaaagg
    21961 tttagtggta ccagaagata tttctgtgat gggcttcaat gatgtcagtg tagcgaaata
    22021 tgtaacgccc tcgctttcta ctgtaaaagt ttataccgaa tggatgggag agctagcagt
    22081 ggagacgatt cttcaattaa gtaattccaa agcaccggtt tcaagaaaga ttattgtgga
    22141 aacagagttg attattcgag aatcaacgaa ataaaagatg gaaaagctgt gggaaaatgg
    22201 agtgataccg cagcttttt
//
LOCUS       DAPBCF010000042        21654 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.043, whole genome shotgun sequence.
ACCESSION   DAPBCF010000042 DAPBCF010000000
VERSION     DAPBCF010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.043"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            144..542
                     /locus_tag="RD508_002009"
     CDS             144..542
                     /locus_tag="RD508_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDT7736562.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1221
                     /locus_tag="RD508_002010"
     CDS             526..1221
                     /locus_tag="RD508_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDT7736563.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1815..2702)
                     /locus_tag="RD508_002011"
     CDS             complement(1815..2702)
                     /locus_tag="RD508_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDT7736564.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2887..3726
                     /locus_tag="RD508_002012"
     CDS             2887..3726
                     /locus_tag="RD508_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDT7736565.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3922..4896
                     /gene="sgrA"
                     /locus_tag="RD508_002013"
     CDS             3922..4896
                     /gene="sgrA"
                     /locus_tag="RD508_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HDT7736566.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5194..5550
                     /locus_tag="RD508_002014"
     CDS             5194..5550
                     /locus_tag="RD508_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736567.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5553..6710
                     /locus_tag="RD508_002015"
     CDS             5553..6710
                     /locus_tag="RD508_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7736568.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6736..7176)
                     /locus_tag="RD508_002016"
     CDS             complement(6736..7176)
                     /locus_tag="RD508_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HDT7736569.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7336..7842
                     /locus_tag="RD508_002017"
     CDS             7336..7842
                     /locus_tag="RD508_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7736570.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            8010..9923
                     /locus_tag="RD508_002018"
     CDS             8010..9923
                     /locus_tag="RD508_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HDT7736571.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9928..10929
                     /locus_tag="RD508_002019"
     CDS             9928..10929
                     /locus_tag="RD508_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7736572.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11131..11337)
                     /locus_tag="RD508_002020"
     CDS             complement(11131..11337)
                     /locus_tag="RD508_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HDT7736573.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11983..12831)
                     /locus_tag="RD508_002021"
     CDS             complement(11983..12831)
                     /locus_tag="RD508_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7736574.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12830..13897
                     /gene="gnd"
                     /locus_tag="RD508_002022"
     CDS             12830..13897
                     /gene="gnd"
                     /locus_tag="RD508_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HDT7736575.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13899..14900
                     /locus_tag="RD508_002023"
     CDS             13899..14900
                     /locus_tag="RD508_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HDT7736576.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14897..15181
                     /locus_tag="RD508_002024"
     CDS             14897..15181
                     /locus_tag="RD508_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HDT7736577.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15214..16011
                     /locus_tag="RD508_002025"
     CDS             15214..16011
                     /locus_tag="RD508_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7736578.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            16025..16858
                     /locus_tag="RD508_002026"
     CDS             16025..16858
                     /locus_tag="RD508_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7736579.1"
                     /translation="MEILSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16876..17733
                     /locus_tag="RD508_002027"
     CDS             16876..17733
                     /locus_tag="RD508_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7736580.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17755..18264
                     /locus_tag="RD508_002028"
     CDS             17755..18264
                     /locus_tag="RD508_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7736581.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18301..18702
                     /locus_tag="RD508_002029"
     CDS             18301..18702
                     /locus_tag="RD508_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736582.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18814..19167
                     /locus_tag="RD508_002030"
     CDS             18814..19167
                     /locus_tag="RD508_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736583.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19201..19644
                     /locus_tag="RD508_002031"
     CDS             19201..19644
                     /locus_tag="RD508_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDT7736584.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19661..20746
                     /gene="uxuA"
                     /locus_tag="RD508_002032"
     CDS             19661..20746
                     /gene="uxuA"
                     /locus_tag="RD508_002032"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDT7736585.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20739..21452
                     /locus_tag="RD508_002033"
     CDS             20739..21452
                     /locus_tag="RD508_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7736586.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7462 a         3324 c         4508 g         6360 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcatgcgata
     1081 acgttaggta aagagctact agatcaagta ttagagatgc cctcgattga taaagcagtg
     1141 aggggcttcc aagaagattg ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa
     1201 aaggtcgctg attacttctg aatcaatttc tccataaaat aaacgatagc cttctcgaaa
     1261 actcgaggag gctatctgac gattcaatat tcattaattt aaagtttggg tgactattac
     1321 taactattac ttatttctca tttaaacgat gtattcccta acctctaata catccttgta
     1381 actctgaagt tacgccagtt ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata
     1441 aaaatatctt tcgtgtttct ctagtataac agaataagaa gaacaagtcc agaagggata
     1501 tttttagtct tttttaaaat aacttttcag tcgagtttga gtttatgata gttgtttttg
     1561 aagcgatacg gcaagtgaaa aaatagggaa gcatgaaaga atctacttaa tggcgcattg
     1621 attcatgtga tagaaataaa aaactttttt aaattatatc ctcatgattg taacaaatcc
     1681 agtgatttgt tttggtacaa ataaaaaaag gccccgatga agttgtggca aaagtggttt
     1741 gcctcaaaaa taagaaggaa tttccaaaaa tcacttctca aattttgcca catccccaat
     1801 tgggtcaaat ttgtttattt gaatatattt tttacataag gatctttaat agttacattg
     1861 tcttttttca tcactttacg gattgtttta tccatgaatt ccgtatcaag agtttttgct
     1921 tcggtagcaa ttttttctag ctcagatttg tatttgtctt tattagaacc tttatcctgt
     1981 ttttttacca tttttactag ataatagctt tgctgataag tcgttggatc tgttacagga
     2041 atgatatcag aaacttcccc gttttttagt ttaaatgctg ctttttttac ttcagtagga
     2101 atctctggat tggttgaatc aaaattcatt tttccatcag tttcctttaa tgttttattt
     2161 tttccataag cttgaacaag cttggagaaa ttttctcctt catttgcttc tttttttgct
     2221 ttatctgctt cttctttagt cgaaaataga atgatctgtg tactaacttc tggatagaat
     2281 tctttccaag cagtgtctag atctttatct gttaatttta cattggcttt caaaccgtat
     2341 tggaaagcca gcatctgttt aaagagtttc ttatatgtct cttctgtttg gccaactgct
     2401 tttaattgtt ccttgtagtt tggaccgagt tttttgattt gttcattata ttcttttgtt
     2461 acttcctttg aagaaatctc ttttccgtat acatcatcaa atgctttgaa gacaatcatt
     2521 ttttttaata gtgtttgatt atttgattta acttttgggt tatcataaaa atcctgaact
     2581 gtaagtgttc cacctttaaa cgttgcaatc gtttcattgg acttgctaca acctgagaat
     2641 agtaaaattg cacatgctga aaggcacata attagtagtt gttttttcaa aaaatttccc
     2701 atcctttcct tattaaaaac agtctaacag aagaattagg gagacagtct ttcattttcg
     2761 taaggttgct gtagatattc ttagttcgta aaaatctatt ctctctatga tggagaacat
     2821 ttacatagtt ttcacgagac aagaaagaaa agggttgtta aacttaatat aaaggaggga
     2881 tgaaagatga tcaggattat tcggttgatt ggatctgttt taatagtctt agttggtttt
     2941 gttttaggaa ttcttgtcaa taatgcactt gcggatatgt ttattggaaa tagtgaatgg
     3001 attggagcaa ttgccggtac ggtcggacat ttagctgttt ttttactagc tttatttctt
     3061 gctagtaagg tcgaaggaaa aagaatagaa gattatggtg tttctgttcg aggaaaagac
     3121 tgggggtatt tagcgggagg tctcgttgtt ggaattggag tgtttctgct tattactagt
     3181 ccattatatt tgacgggggc gtatcggtta gattcaggaa acgcaaacat tgtgccgctg
     3241 ataacgagtt ttattttatt tattgcagtg ggggcatcag aagagctttt attccgtggc
     3301 ttttttcagc atcagatgct tagatttggt ccgttaatag caatgattgg atctgctgca
     3361 ttatttgctc ttttgcacgg attgaatcct aacatgacat ttctggcagt tttcaatatc
     3421 tttttagcag gttgcttttt cagcgcactt atctacagta caggaagttt atttacggct
     3481 attggtgctc atattacttg gaattggaca caaggagcta ttttgggtat accagtcagc
     3541 ggaacgcaag aacaaggttt tttctccact ctgatccaat cgcaaaatac aataattact
     3601 gggggaaact ttggggctga agcatctata tcaactacat tattcttgtt agtcttgatt
     3661 gttggtttgt tactctatgc atataaaaca aagcggatga agaaatacac tgctgtttat
     3721 caataaaaga tgaagaaagc aaggctgata tcggtcttgc ttttttaagt ctgtcattga
     3781 ttaaacgaaa aagtaaacaa attcaagcga atacacgaca tcttttgtta gattttcaca
     3841 actgactgtc gtgttctcat cattttcatt ttatataatt cctttatcaa atagaaggta
     3901 attatatgga gagtgataga aatgaagaaa acagcgaccg tattatttgt tattcttggg
     3961 ctgagtataa ttgcagcaat gattggaatc agtacttctg caaatgaacg ggcaaatgag
     4021 aatctttcat ttactgtgaa aactgatcgg attgtttatg acatgacaca acaagtcatt
     4081 actattccag tcaaaccaaa caaaagcgtg aatgctagtg atgtacatgc tgttctaaca
     4141 tatggttggg atggtaatgg aagttcagaa aaagttattg gggaagttta tttaaaagac
     4201 gtacaatgga ccgctggtat tgagtataca ataatgattt ctgcagaact atcgattgat
     4261 gagatcaaga gtaaagataa agttgatttg attgtttttt atgatggaca gatgacgatc
     4321 acggagaatt tgaaaccaag cagttggaca gttgttggac cgccaagcag tacggatagc
     4381 acaagtagtg aaagcagtac agaaaacacg agcggtgaaa gcagtacaga gagtacgagc
     4441 agtgaaagta gcacagaaaa cacgagcagc gaaagcagta cggagagtac gagtagtgaa
     4501 agtagcacag gaagcacgag cagcgaaagc agtacggaga gtacgagtag tgaaagtagc
     4561 acaggaagca tgagtagtga gagtagcaca ggaagcacga gcagcgaaag cagcacagga
     4621 aaagtaaata atgaacttga tttggtacct atcataccaa ctaaggaaca aaagagaaat
     4681 gcagggagca acctaaaaag tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat
     4741 catcaagaaa aagcgaaaga aacagataat agaaaaagcg atttaccaga aactggtagt
     4801 agaaccttga acaagctaat tacatggatg ggtgtgttac tcattttgat tgtaggagca
     4861 agctattttc gttctctctt ccatcgagtg aaataaagaa taaaagcaac agatctaaaa
     4921 ttgaataaaa cgatagattt ttgagtgaat atttcattcg agagtgctgt attgcctggc
     4981 gaagttgtag ctttgccaga tctatttttg tttactaaca tatttgagaa acaggaaata
     5041 acaggaacac aaatggaaaa taagagcaag aataattgac aatgcacact gcgcatggta
     5101 gtatctctga aaaatcagta acgaatctat ttgtacgtta ttcatgtagc tgtcggaata
     5161 agtctaaata atagataaaa aggagtatgt actttgtttg aagaatttat tgatatcaat
     5221 gaaaggcaag tatatcaatt tttgaactat tgttatgaaa gagacgagaa attatatgtg
     5281 gtgaaggata tcgctttaga tctaaactac accctggcta agatgaattc ggtgattcaa
     5341 caagcagaat cgttttgcga aaggtatcca gaatataaat tatcttttct ttcagaaaac
     5401 aagatgataa aagtcgagtt ttcttctcag tttttactga gtaaagttta ttctatactt
     5461 ttagagggaa cgattggtta tattttactg gattcacttt acaaaggtac ttatcaatcc
     5521 ttagaaaatc ttagtcaaaa aattatataa gtttgcgtac gattcaaaga aaattaagag
     5581 aacttaatac tattttgaaa aactatcatt tatcttgcag cttgaaaaaa ggtaatccga
     5641 tagaaggaga agaataccgt atccgatact tttttcactt gatgtattgg cagtcattcg
     5701 acgaaaatca ttctgatata ttatcaagta taaaaaataa acgtcaacta ttagaaaaat
     5761 ttgcgaaaca tgcgccatat acgcgtagta tagatagaaa gaaatggatc agcctactaa
     5821 gaatttcgtt gcaacgaatg aaacaaggcc actcgattac gtatgtccca gaagagatga
     5881 acaaatttgt gcatccattg ataacaaaag aagagtttac gcattacata ctagagcctt
     5941 tttttgaagc aaacttctgg tcgatgaatc acatcactcc aacagagcaa gcttaccttt
     6001 attttatgtt tggtgtaatg aacacctatt tggaagaaga tttgttggat actccagata
     6061 aagtacaaga aagttggggc tggattgaat cgtctattgt agaaaatttt gaaaaaaact
     6121 tcaagatttg ttttacaact tcagaaaaaa attatctata tgtcaatttg gcaatgatcc
     6181 atttgtattc aagggttttt gggacaaaaa agaaggtgga tgcttttgga aaatcagcag
     6241 aagacagaga ttttcagcat atatttccag tgatgtatcc aatcatgcaa cagtttttta
     6301 gtggggtagc tcgcagaatt ccagagctta atacttatta tgaaaagaac agacggttga
     6361 tttttcaata ctgtatgtta gtcagggata tttttataaa acacgaacaa cctgtcatat
     6421 tctatattca atcaaagtat ggtaaaacac aggaattatg ggcaaagaaa aggatattat
     6481 ctatgactga acgcccaata aaatatagtg catccgctga tcagttacct gatattgtca
     6541 ttagcgatta tcctatcgac aaaaaggcat atgatcaaac gaatacacag atattttact
     6601 ggaatggaca acctacaaaa aatgattggg cgcgtctgaa agctgaaatc ataaaaatca
     6661 ggaatgagaa aaatagatcc atattggaaa aattggattt cgttaattaa gaaaagcaga
     6721 ttgtttatgc caaaattaag acattgcaaa aagattattt tctttaaaat cgacaagatg
     6781 accagaaagc aagagttcgt tgagctcttg ctttctttta gttttagaaa ggaacatcct
     6841 gattttatct tcgctaaatc cagtcaaaag ttttgcagat tggtcgtaga taatcggttt
     6901 tttcaataaa gaaggggatg tacgaatctc aatatatagt tcactcaaac tgagttcatc
     6961 tattctgtga acaagatttt tataactaat agaatgagta gagagcattt cggtcacgcc
     7021 gttgtttgtc aattttagta agtggataaa ttcatttttg gttagtggtt gacgaattaa
     7081 gttctgttcg ataaacggta tatcatggac gataagccaa cgttttgcgc gtcttgaaga
     7141 cgagcagcca gaacctgtat acaatttaat catcatacat tcctccaata gctaagtatt
     7201 tatgaaataa taacatgaag aaatagtcga aaagtgccat ttagaggtgt aaaataagaa
     7261 aatgttgtca cgtataatgg aactagctag ataagaaata ctattaaatc aagaaaaaag
     7321 aaagaaggca caagtatgtc aaacacagcc gacgcaatag tagtgatcga tttacaaaaa
     7381 ggggtatgtt ttgattcttc gccgatacac gaattagaaa cagtgacagc attagtgaat
     7441 aaaagaatca aaacatacga aacgattggg aaaccagtta ttttcgttca acacgaagat
     7501 gctcaattag tgccacaaac aaaaccatgg gagctattgt cggaattatc tattcctgag
     7561 cacagttatt ttgtgagaaa aacccatgcg aattcatttt ataagactaa tttgagtgtt
     7621 ttattaactg aattggactg tcattcgatc gaattatgtg gggcacaagc agagtattgt
     7681 atagatacga ctgtgaagtt tgctcatgga ttaggatacc agcttatgat gtgtagagga
     7741 gcaacgacaa cttatgataa tccttttatg aaagcaaagg aaacaatcgc tttttacgag
     7801 aaaatttggg ataaacgatt tctgacattt ttggagcaat aagttgtttc ttcgtttaaa
     7861 aaaagcagaa tggatactgg tttatccatt ctgctttatt acgtaaaatg agaaaataat
     7921 cctgttctat ttttatggga taaaccattt attttttgta taaaaaatgt ttgcgtttac
     7981 atataattct cctagaaaca taaaaaggag tgaatagctt gagaacaaaa caagtattaa
     8041 agggagcgtt ggtcatctta tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg
     8101 gagagagcat ttcttccgaa tcggaatctc gggaggtaga aaccacagaa actactgatg
     8161 ctggaaatga aacgaaatcg agtacttcac aaacagaaac aaatactgaa acaacggttg
     8221 agacatctgt tactagcaca gatcaagaaa cgaccgctac cacagataac caacaaacag
     8281 aagaagcaac agctacaaaa atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca
     8341 aagagaatgg gacagaaaat gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat
     8401 atttgaatta cttcggtaaa cagatgacag aaatacttaa tggaccaaca gaagacatca
     8461 agtcaaaatt aatagagtta ttagtcactg agcttgctgt taatgattat ggtgtagata
     8521 aagagattat caaacatctg attgctactt atctattgta cgatatcgct tttgcaaaaa
     8581 acagtgtgtt gatgtcgatg cttggaggta cagatgatgg gacaacgcct acagaaaaca
     8641 caggcttcta tccaaataca aaacaacttc atcaaactgt actaaacaaa caagatggca
     8701 aaatgatgga tgtatatgca tattatgtcg atcaaggttc agataaaaca gtcatgatcc
     8761 atggcggatt tcgagggaat tggaataacg ggatcgttac agaagaatac aatgattttt
     8821 ataaggccgg gtataattta ttatttgttg attccagagc gactggtaat agcggaggcg
     8881 attatgtgac ctatggacaa tatgagtcag atgacgtcct ttactggata aatcaagaag
     8941 ttcgagagcg gccatctcaa aagattttac tttatggtgg ttcgatggga gcagctacga
     9001 tgatgtctgt attagcgaaa gatattcctg tcaatgtcaa aggaattatt gaaaattgcg
     9061 gatttgcatc aattgatgaa caactacgtt ttacgtacag ccagacagta gcccccgcac
     9121 taccggatgc cataaaaaat cagttagaca tcattgggga tcaagagcat gaagatttat
     9181 ttatgggcct tttgaaacaa tactattttg atcaggagat gcatttggat acaaaagctg
     9241 ctctacctac gattggaatg tcagattcat tgcctaaatt gattatccat ggaacagcag
     9301 atgatgtagt acctgtgtct aacgcgcaaa aattatatga gttatcagga gggtataaag
     9361 atcttttatt agtagaagga gcagggcatg gaaaggcaca ggaagttgac catgctgcct
     9421 acacgaaaca tgtaacggac tttttgaaag tagtgttcca tgatcagata aacgtaaagt
     9481 atgtggatga aaacaataaa agtctactca aagaccagga cgaaatccag ctttacggag
     9541 cttatggaga aaattatatg acagagcaaa agacattcga aggatacgaa ttagcaaatg
     9601 ttgaaggacc gactgaaggg atttttaatg agacgatacc aactattatt ttctattaca
     9661 aaaaaatccc agtagctcca ccaaaaaagc aagatccgac agagaatgca gacaataagg
     9721 gaaagaatga acctcgagag gatcaatcaa gtgatgatac gcaaccgatt cagatgacag
     9781 tgaaagtaca aaaaaagaca gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga
     9841 aacattcgct tctcatttat tcaggtggat ttttatctgt tagcacgatt atcacatgga
     9901 tttggcgaag aaagagaggg taaatgaatg aaatggttca agcgaatagt gattgcagta
     9961 ccagttatca tcgtagttat tttagtcact gtatttttga ttaatcaaat cacaccaaag
    10021 ccgattagct tgcttgttag aaaacaattt gacacaagtg aaaaagaaca agtatatgcc
    10081 cgaccagatg atttccagca aaaaatcgaa caaatcgata taaaaaaaga aatatcctat
    10141 ccttcaaagt acaaaaataa taatatggat atctacacac cgaaagtgga aaagaaaaaa
    10201 ttaccgattc ttttctggat gcatggaggc gcatatgtag gaggggataa aaatgattgt
    10261 cgtgattatt tggaatatct atgttcagac acgcagcaaa tcatcgtaaa tatagattat
    10321 gaacgatcac cggaagcaaa acatcctaca ccagttatcc aattgaacga agccattcaa
    10381 gcagctaaaa aagagataaa agatcaagca gattggtcga atatttcgat tggtggaaat
    10441 tcggcaggtg cacaaattag tggagaatat ttgttagcac ttcaaaatga agaaattaaa
    10501 aaagctgatc atcttgatcc gactttggag aacaagcaga ttacgaagtt tatttctttg
    10561 tctggtctgt tggatccttc tgcacttact caagtaagtg ataaaatctc tagctttctt
    10621 tatgaaaaat gtggatgggc ttactttgat aataaggact ttgaacaatc agagaaggtc
    10681 aaaagtttag ccttggtcag acatgcggat cgttggacgc aaaacacatt cttaacggat
    10741 ggaaatacaa atacgtttac gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg
    10801 ggggtgaaag tcacaaaagt agattatgcg gagaaaaatg ctgttttgaa ccatgaatat
    10861 cagtttgatt tcagcaataa acaagcgcaa gaaacatatc aaaagttagt aatgtttttc
    10921 aaggagtaaa gtcttatgat gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca
    10981 aggagcaatt tcaataaaca agcttttcat ggtttatgaa tattgtaact tgtgactgag
    11041 gagttagaga tggcaagggg caccttttat tcgaaatttg ggaatatcac acgattattg
    11101 tcacgatctc ttttacgtaa attttataag tcagatttgt tgttttgatc gtttaaaaaa
    11161 agcaacaaat ccgaagcctg cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa
    11221 gaatgctggt tccactaata ttccgttgtt attgatataa ggctgggaac aaagatgaat
    11281 agcaaataaa atcaatgcac tagcgaaaaa aagcaaagaa atatggatag ctttcataag
    11341 cagcacctcc ttttttataa ttgtatgata aatagattaa gaatctataa atgtgacaag
    11401 tttgttagga tgtgaataaa atgatcatct agcgaacttg aaacaaagat ggctaatgat
    11461 aagcaattaa tgattcagca atcagatagg tacaaagttt accatcatac gtctagacca
    11521 ataatagaaa atatgggaat ataatagaaa agatttagga tacccccaaa agaatttccc
    11581 caaaaattcg atgtatccta aactttttta ttttacataa caatcatatc aactgtgaaa
    11641 taaaattaca aatgataacc taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt
    11701 aattcaccaa aatttttttt aattttttag aaaataagaa acaaaaataa taaaaaaaag
    11761 aaaagataaa ttttttacta ctgtatacta actttgttat cgcatctaac aagtaactcg
    11821 aataatacca atacaacctt ctccaaagat gcgatgacat acgttctaac ccaccgacta
    11881 ttgatgttct gtaccaccct tgcagaacca aaaaagccac taccaaatat ttggtagtgg
    11941 ctttttttgt tttatggatt tttcgctttt tctgttatgg tgctattctt tgatttcaga
    12001 aatagtatgt cgaactttag cgatagaacg acgtgattct ttttcgttgt aaaacatcaa
    12061 aatcacatat agagagtcca aaatgcttag ttgagaaata cgggaagcta aagcttcaga
    12121 tcggaattct gtttcttcag aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga
    12181 agaattagct tggctagtaa taacgattgt ttttgctcca gtttttctta cggtttcagc
    12241 aatatggatt gtttcttttg attgccctgt gtgagaaatc aaaacagcac agtctttttc
    12301 cgtcaataaa gaagcttcca tcaattgaat atggtaatcc gtgctgtgag aagttgcgat
    12361 aggggaacgc aaaaatttat gataagcgtc agttgctaca atctctgaac cgccaacacc
    12421 gaaaaaatag acacgtttag attcattgat aatagtagcc gcttttttta gatccttttg
    12481 ttgtaacaac ttttttgtgt catttaaagt tgaaatacta gactcgaaca ccttttgcgc
    12541 catagtgagc tcagtatctg ttttctgaat attttcgtgg atagaaatag cagatagatc
    12601 attttcttgg atcaacatgg ccattttaaa atctttaaat ccattataac caagtttttt
    12661 tgtaaattga aaaaaagtag agtcagcaat gcccagttca cttgctaaat tgctaatagg
    12721 actatgactt actttgcttg gattttctaa aatataatcg gcgatagcct gttcttttgg
    12781 gctgaagtcg ttgtacattg ttttgatttg tagtcttatg gagacgctca tgagaattcc
    12841 tcattttcat aataagatta tcattttttc cgttctcatt aatgttaaag atacaaggag
    12901 agtaggaaaa aatcaaacaa aaaatatttt tgtaaaatct atttacaaaa aaattttttt
    12961 gtataatgag ggtataagaa atggaggcgc tatcatggaa attggtgtaa ttggtttggg
    13021 aaaaatggga ttgaatttag ctttaaactt aaaagagcac catcacaaag tacaaggact
    13081 cgacatttca agtacagctg ttagtcaggc aagagaaaat gacattcctg cttatcaaga
    13141 gatctctgaa tttctagcta cttttgagca gaaaaaaatc atctggttaa tgcttcctgc
    13201 tggagagata accgaaaaca tgttaagaaa actttttcca aaactcggac caggagacat
    13261 tattattgaa ggcggaaact cttattataa agattcaatc cgtcgagcag aagagtttca
    13321 gaaaaatgaa atcggttact tggattgtgg gacttctgga ggaatcgaag gagcacgaca
    13381 tcaagcctgc ttaatgattg gaggagataa agaaactttt ctatccgtgg aacaattatt
    13441 caaagatgta gcaattgaaa gaggatatct gtatgctggt gcatccggaa gcggacactt
    13501 cttgaaaatg atccataatg gaatcgaata tggaatgatg caagcaatcg gtgaaggatt
    13561 ccaacttgta caaaaaagtg agtatgcttt tgacttggaa caagtcgcac gtgtttggaa
    13621 tcatggttcg gtgattcgcg gctggctgat ggaaatcatg gaagatcagt taaacgaaca
    13681 tcccaattta agtaattatc ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt
    13741 tgaaacagcg ctagaaatgg ctgttccagt tccagtaatt gcaactagtt tgttcatgag
    13801 gaatctttca caggaagaag atagtttttc agcaaaagta gtttcagcac taagaaatgg
    13861 gtttggcgga catgaaatag ttgaaaaggg tgagtaaaat gccagattat catatagcaa
    13921 tcgttaattc cagcagtttc ggaagagtct ttccacacca cttggaaaga ttaaagtcag
    13981 ttggagacgt tcatttcttt actgttgatc aagagattcc aggaaaagaa ctagcggagt
    14041 tacttaaagg attcaatatc attattgcaa gtgttacgcc attttttcga cgagattttt
    14101 ttgaaaacaa agatgaactg ctattgattt cccgacatgg tattggttac aacaatattg
    14161 atttaaaagc agcaaaagaa caccagacaa tcgtatctat catacctgct ttagttgaac
    14221 gaaatgctgt agcagaaaat aatataacta atttgttgtc catgcttcga cgcacgacac
    14281 aagcacaagc aagagtcaag gacgatcgat gggaagatcg ggcggagttc gtcggtagga
    14341 cgctgtttaa caaaacagtt ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg
    14401 aaattttgcg taacggtttt cgctgtgatg ttctagctta tgatccttac aaatcagatt
    14461 tatacatcga aagctttggt gcaaaaaaag tagaacttca agaattactg gaacaatcag
    14521 atatcatttg tttatgtgcg aatttgacag aagagaacta tcacatgatt tctgataaag
    14581 aagtcgatca gatgaaagaa aatgtttatc tatctaatag tgcaagaggc gctctagttg
    14641 atgaagaagc gatgattaat ggtctgaaaa gcggaaagat cgcaggatat gccacagatg
    14701 ttttagaaga agaaccggga cgtcaagatc atccgtattt agcgtttgaa caagtagtga
    14761 ttacgccaca tatatcggcc tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg
    14821 tcagagatgt cgaacagatc agtcagcacc ttcttcctga acgttctgtc cagacaaaga
    14881 gcaactatat aaaaggatga tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc
    14941 tcaattttat ttatatgaag aaggtggtat ttcaaaagtt tctgatctct tgaaatcata
    15001 cggcgcgaaa agagtactgg tcacccacgg aacggtatca tgggaaaagg cgctacctaa
    15061 attagtattt ttgaatgacg aaacgattca atttttttat catcgttatt ctggagaatg
    15121 tagttatgct gaagccagac gaatagctac aatcatcaaa aaaatgaaat cgatttcgta
    15181 gttggcgttg gcggaggaaa actgaccgat ctagtgggtt atagtgccaa tcttgcaaga
    15241 atcgatttcg gagtcatccc tactttagct agtaattgtg ctccatggac acctcttgct
    15301 gtcatgtata aggagaatgg acaagcagaa gggaaaacag aacactttta cagacaagct
    15361 gcttttttta taacagatcc ccaattagtg attgattccc ctgttccata tttcattgcc
    15421 gggttagcag atacactagc aaaatggtat gaatctgagc tcatcttaga acaagatttt
    15481 ttgcaagatg aatcattttt gaagctagca caagatactg cgaagatctg caaagaagag
    15541 attttgaatc attctgctaa agcaatccaa gatatggcac aaagaaaact gacatcggag
    15601 ttcaaacagc tttcagagat tatctttgct gttgctggtt tagttggagg attaggagat
    15661 aaatacgcaa gaaatgcggc agcacatgct atgcatgacg ctatcagtaa atatattccg
    15721 gaaagccatc gttttctaca tggagaaaaa gtagcgtatg ggattttcta tcaactggca
    15781 ctagaaggtc gctgggaaaa aatagacgag ttatatcctt tgtatcggga attagaactg
    15841 ccggtttctc tagaacaaat gggattattt ccgaaagata aacagataat agataaaatg
    15901 gctgaattta ttgattcgaa agagaaagtg catttgattc ctatagaggt aacacagaaa
    15961 tcactgatac agtcaatgat ggaactggaa ggttatatca gaaagatctg aaggaggagg
    16021 acacatggaa atattaagtg tagtacaaag tttgttgatt gctttatggg tagccgcggt
    16081 tatgtcccgc tggttaggtg gaggagccac gttgacctta cgtttttctc ctttgatgac
    16141 tggattagtc gtcgggttga tcatggggga agttgcacaa gcgatgattg ttacagccgc
    16201 tttgcaaatg atttatatgg gggttttttc tccaggagga tcaatgccag ctgaaccatc
    16261 tattgcagca gctatcgcag taccagtcgc attattaggg gatctgtcgc cagaagcagc
    16321 gattgccgtt gcggtgccag tcggattgct cggaagttac ttgtatcagt ttcgtttttt
    16381 catcaatact tttttaggta aatatacaga caaagctgta gaagatttga atacaaaagc
    16441 tatggcccga tcaattattc tttatccaac ggttgcctca tttttattat tcgttccgct
    16501 tgttttcatt gctttatatt taggggcgcc attgatcgct gatgtaatca aagctttaga
    16561 gggaacagtc gttatccaca ttcttgaagt agtaggtgga gggttagcgg caatcggtat
    16621 cgcgacaact gtatacgtta tcggtcgaaa agattatctg gtctttttct tccttgctta
    16681 ttttatgagt gttgttttga aatctttaga tattacgatg gttacttatg ccatttttgg
    16741 gattattatc gctttgatct ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac
    16801 aagcaataac aattcagcat cttttgatga cgaagatgac tatgatgacg gattttaatt
    16861 taggaggaat gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc
    16921 acgaaaaaag atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac
    16981 tcttttgaac gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa
    17041 ctttataaag atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac
    17101 actcaattaa gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcaa
    17161 agagcagaag aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac
    17221 acgaaagcgg gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc
    17281 gtccaatata tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc
    17341 gcactttttc cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca
    17401 agacaagctt tcactatggg ccgtaatgct acaggcctaa tgcaaaacac tggtgttcag
    17461 acagcgattg aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac
    17521 tatgtaaaag tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag
    17581 gaaattcttg atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac
    17641 ttgttctata cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata
    17701 ttaattgtgc tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt
    17761 gtagtcaatt tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta
    17821 tctcaaaaaa gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa
    17881 tttatgagag atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt
    17941 acaccagaga aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt
    18001 ttgatcgcaa aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa
    18061 gaattgaata ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa
    18121 tctgtttatt taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc
    18181 gtaaagaata tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta
    18241 ttgaacaagt ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa
    18301 atgaagaaga acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag
    18361 cgccgtacaa aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt
    18421 atgagaacag atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt
    18481 tatgttggag atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt
    18541 catgcattag gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac
    18601 tctatattat tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat
    18661 aacaaaaatc ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta
    18721 gcatttggga gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa
    18781 acttttattc gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat
    18841 gatccgagtg tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac
    18901 agcgtgagat cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca
    18961 gatacaccgc tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa
    19021 gttgataagt tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg
    19081 cagttcttct atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc
    19141 aatcagatta ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta
    19201 atgttggaaa tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg
    19261 gaagtaattg tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac
    19321 atccaaacat tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc
    19381 atgctagtat ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc
    19441 aatgaactga ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca
    19501 atgttgttag aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa
    19561 caaattgtca aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa
    19621 aaattagatg aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg
    19681 gtatggtgaa aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa
    19741 tgggataatt ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat
    19801 tgaggagttg aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt
    19861 agcgatccac gatgcaatca aggcagggac agatgaacga gattactata ttgataacta
    19921 tatacgaaca atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa
    19981 accaattttt ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc
    20041 tcttttatac gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat
    20101 acacagccag tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt
    20161 cgctcagctg gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac
    20221 ttatttttta gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca
    20281 tccagatgat ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga
    20341 cttgaagaaa attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg
    20401 atctttaggg gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg
    20461 catccatttt gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac
    20521 ggcacatccc tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca
    20581 agaagggttc gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc
    20641 tatgcctgga tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata
    20701 tgaggcgata agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca
    20761 tctttgatat ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa
    20821 aatcagcaca aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc
    20881 aaacagaaat ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata
    20941 tcaaatggcg agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag
    21001 tatatacgaa aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata
    21061 caatcgtggc ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc
    21121 tatatgcctt gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac
    21181 cagagatctt tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat
    21241 ttgaagactc gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca
    21301 tcaaagatca tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg
    21361 taagtttata tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac
    21421 gatttttaga aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt
    21481 atttattgtc ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag
    21541 tatctacctt atttgtagtg aacaatttag aacaaacaca aaacgcatct actgttatct
    21601 accagtagat gcgtttaaag agaagaacga gaatcgtcca tatgagggtt tcca
//
LOCUS       DAPBCF010000043        21617 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.044, whole genome shotgun sequence.
ACCESSION   DAPBCF010000043 DAPBCF010000000
VERSION     DAPBCF010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.044"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            68..808
                     /locus_tag="RD508_002034"
     CDS             68..808
                     /locus_tag="RD508_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7736587.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(1232..1402)
                     /locus_tag="RD508_002035"
     CDS             complement(1232..1402)
                     /locus_tag="RD508_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7736588.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1596..1775)
                     /locus_tag="RD508_002036"
     CDS             complement(1596..1775)
                     /locus_tag="RD508_002036"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736589.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            2162..3274
                     /locus_tag="RD508_002037"
     CDS             2162..3274
                     /locus_tag="RD508_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7736590.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3352..3645)
                     /locus_tag="RD508_002038"
     CDS             complement(3352..3645)
                     /locus_tag="RD508_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDT7736591.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3813..4127
                     /locus_tag="RD508_002039"
     CDS             3813..4127
                     /locus_tag="RD508_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HDT7736592.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4148..6127
                     /locus_tag="RD508_002040"
     CDS             4148..6127
                     /locus_tag="RD508_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7736593.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6140..6466
                     /locus_tag="RD508_002041"
     CDS             6140..6466
                     /locus_tag="RD508_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HDT7736594.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6482..7000
                     /locus_tag="RD508_002042"
     CDS             6482..7000
                     /locus_tag="RD508_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736595.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            7000..8352
                     /gene="celB"
                     /locus_tag="RD508_002043"
     CDS             7000..8352
                     /gene="celB"
                     /locus_tag="RD508_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDT7736596.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8436..9941)
                     /locus_tag="RD508_002044"
     CDS             complement(8436..9941)
                     /locus_tag="RD508_002044"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HDT7736597.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(10033..10623)
                     /locus_tag="RD508_002045"
     CDS             complement(10033..10623)
                     /locus_tag="RD508_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7736598.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10802..12448
                     /locus_tag="RD508_002046"
     CDS             10802..12448
                     /locus_tag="RD508_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7736599.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12497..13216
                     /locus_tag="RD508_002047"
     CDS             12497..13216
                     /locus_tag="RD508_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDT7736600.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13695..14642
                     /locus_tag="RD508_002048"
     CDS             13695..14642
                     /locus_tag="RD508_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7736601.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14654..15574
                     /locus_tag="RD508_002049"
     CDS             14654..15574
                     /locus_tag="RD508_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7736602.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15615..17072
                     /locus_tag="RD508_002050"
     CDS             15615..17072
                     /locus_tag="RD508_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7736603.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17417..18031
                     /locus_tag="RD508_002051"
     CDS             17417..18031
                     /locus_tag="RD508_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7736604.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            18024..19748
                     /locus_tag="RD508_002052"
     CDS             18024..19748
                     /locus_tag="RD508_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7736605.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19745..21196
                     /locus_tag="RD508_002053"
     CDS             19745..21196
                     /locus_tag="RD508_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7736606.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
BASE COUNT         6974 a         3674 c         4364 g         6605 t
ORIGIN      
        1 ggggtatgaa ttagatgcga caccgatcga gtttgagatc gaaagaagtc agacagcggt
       61 ggtagaattg acgaaagcaa accgacttac accaggcggt gtcgtgttga caaagatcga
      121 tgaccaaagc ggggaagtcc tgcaaggagc tgtttttgag ttacaagatg ccaatggaac
      181 cgttctgcag tcaggtctaa ccacaggagc agatggaaaa ctggcgattg acggcttagc
      241 accaggagtg tatcagctgg tagaaaccca agcgccaacg gggtatgaat tggatgcgac
      301 accaatcgag tttgagatcg aaagaagtca gacagcggtg gtagaattga cgaaagaaaa
      361 tcgacttaca ccaggcggtg tcgtgttgac aaagatcgat gaccaaagcg gagaagtcct
      421 gcaaggagct gtttttgagt tacaagatgc caatggaacc gttctgcagt caggtctaac
      481 cacaggagca gatggaaaac tggcgataga tggcttagca ccaggagcat atcagctggt
      541 agaaactcaa gcgccaacgg ggtatgaatt ggatgcgaca ccagtaactt tcaagatcga
      601 aaaagaacaa gaagtggcga tctttttaac aaaagagaat agaaaagttg ctgatagctc
      661 agatataaga ggaaacaatc caacaagcag tggaaataag catcttccaa aaactggaga
      721 aaccatcatt agccagttta tattgtcaat attgggtgtg ctacttgttt tcatcagtat
      781 aaaatttaga aagaaacgaa atatatgagc taaaataaaa aattgaataa gcatagtttt
      841 taaaatcaac tagtacccat caattgaatg gaaactaccg attttagaag gggtatacaa
      901 acaaatatta gtatcggagt agagaaggtt gaacccaacc agtaaataag taaagacaat
      961 tttgtgctgc gttgagaagt gaaaaataaa cctttgtagt aatactagtt aataaaaaat
     1021 atacaaaaac actgcgaaaa tcattcttga gtttcgcagt gttttttgcc taatgactca
     1081 agtttattgg gtaatacttt gattttcttt ctacaaataa tcagcgatca gttgtaattt
     1141 tttctctagt tttaatggct ctttgtcaat aaggagaaaa acaagtcggg tcttttgtct
     1201 cggaaagctt caaccaactc gtgaataaag gttacgcctc cttgaaaggc gtggaaaaac
     1261 caagtaatcg atcaatcacc aatttcgcat ttggtagaac atgtttggtg agctgaaagt
     1321 aggtggcgtt catgtctgta actaagaatt ctatttcttt aggattagtg cagctaagga
     1381 aatagtttgt taatcgagga attttttgtg taggtaaatt ttctcgatta atttttctgt
     1441 ctcgccatcc gcggaaataa aactcagttt atcctcaacg gaaacgtgag aacgaaattc
     1501 acaaccctca acactcaaga cagaattctt ttggaagact ttggtaaata gcttctcaac
     1561 tctttcaatg tgcgaataac ggttgtcaaa gatacctaac aacttttcga aataaaaaat
     1621 aacgacactt tttcagtcag taaagaagtg attttatgtc tgacatgatt tgaaatcgag
     1681 tgccttggac ggataaaata actttgagcg ttccaatggc ttcgacagtt tttacaggta
     1741 tagcgctgct tttttaggcg tataaccatt ggcatatgat tatattattc aaagtggaca
     1801 atggtttcct tcttcttgtt tttcaccacc attaatttcc tatttccatc taccacagca
     1861 gaaccacaat ttctacagac acatggagca gggaagagaa ctgcagcaac gatcaatgtt
     1921 tttttcttct gtaaggtttc gtaagagacc tctgtaatca tcaaattttt gtctattgat
     1981 ctcagaattt ttttgataga accattcata aagcatatcg ttctctcagt tgtttatttt
     2041 gtggtgattt aatcatacaa gaaaacgata tgttttttta taaaaacatg aataggaaaa
     2101 atagttgaca agaaaatgac aacgccatat gatgttccat agtatttaca acctgtcata
     2161 gatgactgta aaaaataaaa gtaaaaagaa aggacgacaa caggtggatt tttatcagtc
     2221 tctacaacta gatccgttta ttttaaaaca aaaaatacga gaagcagctt ctaaaaaaga
     2281 aaagtgcatg tatatttgtt cattgttttt acgatcatta ttcatcgtat tgtttgccat
     2341 ttgttttatc attataatta caacattatt tgaatcgaag cataaaccat acgctgtggt
     2401 tttattctgt atgttgatga gtattcgttt tgttgacttt ggttataaga tttcccattc
     2461 gatcataggt ttagcaatcg tcatgttctc actattagta gcaccgtatg tccagctgat
     2521 caaatggtca gttatgggca tgttgattca ttttatttta ctaagcagca tattaatggc
     2581 aaccgctagt gatcccaaaa tggggaatgc ttctttgtac ggcttttcat atctctttat
     2641 tgtttattcg ttacctaaag attcgttgaa caagaatttc tttacacaaa caagtagctt
     2701 attatttttg tttttttgtt ggttttcagt tctcctttac agaaaacatc gagaaaagaa
     2761 caaagacaaa agcttgttta aagagatttt tttgaaaggc atgtattcgc aggaaaaaat
     2821 ttggatgctc atctatgcat ttggcattag tcttttgatc gttgcaggag agtatgtccc
     2881 ttttcagcga ttgatgtggg cagggtttgc attttcttct attgtatcta gctatggatt
     2941 gatgtcgatt ggtttcaaag aacgagcagt agaccgaatc attggctcat tgattggatg
     3001 tgttttattt attggtatca gccaatttat tccttttaac tgggtcggta tattaggtgg
     3061 tctagcttta ggtgtttgtt ctacctatag atataaaaca gtttttaatt cttttggtgc
     3121 tttggcaatc actgccagtt tattcggggt tccaggagca gtaacgatcc gcatttttga
     3181 gaatatcctt ggggtatgtt taggaatcat gtatattggg gtgactgaaa tacttatccg
     3241 aaaaataaga gaaaaacacg gtttgaatca ttagatgaga tcgaataaaa aataaggaaa
     3301 aagtgaagat acacatggat gataaattgc tatcattcca tgtgtatctt tttacggtaa
     3361 atcagtgaaa cgttcgactt tcatttttaa tttatacttt ttacggagtt cgtttatttg
     3421 agccatcatt tcggatttgt gatgcttttc gattgcttct tcatctttcc aacggtcgat
     3481 cagtaaaaga gattctggat cttctagtgg aaagtaatag tcatatttct cgtttccttc
     3541 ttctgcacga atcgctttga caatgtttct ttcgaccatt tcttctgcaa attttctggc
     3601 ttgtccattt gtacttgtat acaaaatatt cactgtgata ctcactaaat cccctcctga
     3661 aaaaattcta tcactagtat atcacggtgc cagaaattat tattcaagat atgatacaca
     3721 ttttttccgc aatgctacgg aaatatatat tttgaataga aaacgcttac aagatatgct
     3781 tggtttataa aaataaaagg agtgattgat ttatgaaaaa agcattgatt atttgtgcgg
     3841 caggaatgtc atcctcgatg atggcctcaa agacaacgga tttctttaag caaaaaagag
     3901 aagaggtact cgtagatgca gtttcagcta cagaaggcga taatatgatt aagaatagtg
     3961 attttgattt atttctgatc agcccgcaaa cgacgatgtt tttggataaa ttcaaaaaat
     4021 taggagaatc tgttggaaag cctgttgtta gtatcccttt ccaagcgtat gtcccaatcc
     4081 ctacaggcat ccagaagtta gcagaggtga tcgaagagaa catatgatgg aataggagtg
     4141 gatgataatg aaacagaagg aaaaattgct gttgagatat ttgattgatc acaagaagga
     4201 gtatgtcacc agtcaacgtt tagcttctga attgttatta tctgatcgga caatccgtaa
     4261 ttacttgcag cggatcaaag agttagtaga aaaaaacgga ggtaagatca ttgctaaacc
     4321 aggttatggc taccaactgc atattttaca aagactgaca tttgacttgt ttttgagtcg
     4381 gcaagaaata gtacctggat atgctagaga accgcaagga ttttatgagt ccgaagatcg
     4441 acaaaagtat atattgaacc aattgctttt ggaagatgcc attcttttta tggatgattt
     4501 ggcagaagag ctttatatca gtcgttccag tttgacaaag gacatgcaag aaatcaagga
     4561 gcgattgatt ccatattcac taaaaatcgt ttctaagcat ggtcaaggga catggatcga
     4621 aggggaagaa agaaatcgac ggcattttat catggatact ttttttggaa accattatgg
     4681 aaattcattg aaagaatatt tagggcaaag ccgttttttc ccagacatca gttttgaaga
     4741 gctagtcatt atcattctcg atgaaacaag agaagctaag ttaaaagttt cggattttat
     4801 catacagaat ctgactttac acttggcttt ggggatcaaa cggctccgag aagggtttga
     4861 aatcaaggaa ttaggcatcg aacaagaagt ttctaagcga gtagagtatc aagtggcgca
     4921 gcggatcgtt caacgtattg aggtaatcgc aggtgtatcg tttcccgaag aagaaattgc
     4981 ttatttgaca ttacatctca tggctaagtc gaatcacaaa gaaaatcaaa atgatcagga
     5041 actatcaaag gaattagcga aagttctgaa aagattgtct caggaatttc atttttcatt
     5101 agtagaggat ctccagcttt tcaatggact actcgatcat ttgtcaccga tgatgattcg
     5161 attgagccga ggtattcgca ttgagaaccc attgactgag gagataaaga aagaaaatcc
     5221 caaagtcttt gacgcagtaa aaaggcattt cagcaacatg ccggctttga aaaactatac
     5281 catcaatgaa gatgaatggg cctatttggc tttgcatctc atggcggcat tggaaaaaga
     5341 aagagctgcg cataaactac atgcattgat tatctgtgca acgggttacg gcagtgccca
     5401 actattaaag aatcgcgtag tcagtgaatt cggtaaaaat attacagtgg taagtgtaaa
     5461 aggctattat gagatcaatg aaacaacttt aaaaggaatc gacctgatta tttcttctat
     5521 tgatctttcg acaatgtttt tcaaaattcc agttttacat gtcagtattt ttttgaatga
     5581 agatgatgtt cgtaaaatac gaaaggtagt tggagaatct ataccctatc attcctcaga
     5641 tagaccgata ccagcatttt ctctacagca aaaaaagcag atttacaccg aacagttgtc
     5701 tgaaaaattt ttcaagactt atacgtacga accgaaaaag gaagaaattc ttcatgattt
     5761 gctgcaaaag ctgagcataa atgaagaaga aggatatata agagaaatgc gaaagcagat
     5821 ccagcaacgt gaaaatatgg gacaaatcat attcagtgat acagtggcag tcccacatcc
     5881 cgctgttcca gttggaatcg aaacaaaggt agccgttgca ttgattcctt ctgggatgca
     5941 gtgggatcaa tatcaagaaa ttcattttgt ttttttagtt tcgccttctt atgtcgaaaa
     6001 tgaaggaatt acggtcgtga ctaaagcaat cgttaggtta gttgaccagc taaaagtaca
     6061 gcaggaaatc ttagctgaac ctatttttga gaatttcagc agtaaattta tcaaactgat
     6121 cgaataagga ggaaaacaga tggctgaaaa aataaacagt gaaacactac aagtgacttc
     6181 ttttgatatc attttccata gcggaaatgc acggacactg atacatgaag catttcgctc
     6241 gatgcgtaaa gagatgtttg aagaagtaga agagaagttg cgacaagcaa atgaagagat
     6301 tcttcatgcg catcagtcac aaactcaact tctgaaagaa tatgccagcg ggacaaaaat
     6361 agaaatggaa attatcatgg tccatgcaca agatcatctg atgacgacga tgacattatt
     6421 ggaagttgca caggaaatga attatttgta tcaaaaaaat aaatagaaag gaaggatcat
     6481 tgtgcaggat acagtaaaaa ggaaaatcga attagaaaaa aagcaactta gtttgaaaaa
     6541 catgtatttc aatcgttatc taatcgtacg ttacctgact gcctttttct ttttcatgaa
     6601 catgcaatgg atgattctgc ttctatcagc taaaagttta ggaagtagtt taccgatgat
     6661 tctgatttta gctattttgc ctgcagtagg agaacaagta aagctttatc gaaaacacca
     6721 aacgaacgtt ccatggacaa agtggtattt tttgttccag agtgtcttta atttattagt
     6781 gattccagtg ttgtttacct caggatttac attcttgtat ccttttatgg caaataacaa
     6841 tggaggacag ttatttgttt tcattcttgt tgtaagcggt atttttgcca gtgcatttat
     6901 acagtatcgt ttaaagaaaa tttcactcaa ccaagaccaa cagtatatcc gtattaaaca
     6961 atatgaaaaa gcgttatatt taggaaagga gaataactaa tgtttgattt tttgcagaaa
     7021 tacctgatgg gacctatggg gaaaattgcg caacttaaaa tcgttcgggc tgtcatggca
     7081 gcggggatgg cttctattcc tttcacgatt gtaggctcga tgtttttggt tttaaatatt
     7141 ttgccattac cgttcccatt tttagaagga ttttttaatg caactttttt caaagttagt
     7201 gacttgtaca tgatcgtcaa tacaatgacg atggggattt tatctattta ctttgccatt
     7261 gtgtttgctt atgaattaac gtcaattgaa cgagatgaac aaaaattaaa tgttaatccg
     7321 ctcacggggg cattactatc tgtttttgca ttctttatgt gtatccctga attgatcatg
     7381 actgatggta aaatcagctt gattgcttct atcaatgaga cagaaactgt agtaaatggt
     7441 attaggatgg gctcttttgt cgaacgttta ggaacttcag gaatctttac agctattatt
     7501 atgtcgatta ttgcggtcga attgtattgt atgtgtgtca agagaaattg ggtcataaaa
     7561 atgccagatg ttgttccgcc aggagtttct cgttctttca ctgctctgat cccaacattt
     7621 gtcattgcgt ttgtggtgat gatcatcaat ggattattag ttgcactagg aacggatatc
     7681 ttcaaaatga ttgctatccc atttgggttt gttacgcagt tgacgaatac atggcttggt
     7741 gtcatggtga tttatttctt gatccatgca ttgtggatcg tagggatcca tggagcgaat
     7801 atcatcactt ctttcttgac cccgatcgta ttagctaata tggcagctaa cgcacaaggc
     7861 gcaaattatc cgttggcagg agaattcaac aattcttatg taaccgttgg tggatcaggt
     7921 gcgactttag gattgatcat ctttattgca ttcctcgcga aatctgatca gctgaaagtg
     7981 ttaggaaaag cctcacttgt accaggatta ttcaatatca atgaaccaat cattttcggg
     8041 atgccaatcg tctacaatcc ctatttagcg gttccgtttt tcttagctcc gatggcttct
     8101 gctacactcg cttattttgc cattcggctg gaaatcgtca aaccgatgct tgcacagatg
     8161 ccgtggcctt caccagtcgg gatcggagca tttgttggta gtggtggtga ttggaaagct
     8221 gctgtgttag cagtcatttg tgcaatcatc gcattcatta tctggttccc atttatcaaa
     8281 ttctatgata ataaattatt aaatgaagaa agagaaaagg cagcagaatt agctagtgaa
     8341 aagttaaaat gatttctaag aaaaaaggaa ctgtgacaaa aaatcacagt cccttttttt
     8401 cttagaaatg ggaaaccact agtatataaa taccattatt cttcaatcaa ccgcttcacg
     8461 attgcataat ccccttcata aggttcatct acaccattga ttttttgata gggatccacg
     8521 ccttttcccg caataacgac tgaatcttgc ggagcgcttt ctgctaaagc gcgtcgaatc
     8581 gcttcaggac gatccatttc ataatgaacg atcaaatctg gattagtaat tgcttcattg
     8641 atttcttccg cgattttttt cggatcttca aatgctgggt catctgccgt caaaaaggcg
     8701 atgtcagctg tttctgatag cacttttcca aaatcatgtc gacgggagat tgctttgttt
     8761 cctgggctgc ctaatacaac aattacacgg ccatctggat gttcattttt ggcaaatttc
     8821 agcaatgttt tcaagcttag ataattatgt gcatagtcca catagacatg cgctccattg
     8881 gattggatca attgatccat tcggcctggt acacgagctt cttttaatcc gtcttgtgca
     8941 tcttgactgg aggcacctgt tagtgctgcg gcaatgatcg cactggctgc attttcttgg
     9001 ttgaatcctc cagccagcaa aatatcataa gcagtatcgc agatagctaa gcgatcttca
     9061 tgagaagata aagtaaaacc gtgagtacct ttatctgaac ggatcacttg ataattgctt
     9121 tcttccgaac gaccataagt gatcgttgga atctggaata gatcggctgt ttccctaagt
     9181 aaatcaaaat agtcactttc atgatttaaa acaactgttt ttgaattcaa gatcaattgt
     9241 cgcttgcaat agaaatagtc atcaaatgtc ggatgttcga tcggactgat atggtcaggc
     9301 gagatattca agaagattcc gacatctaaa gtcaagccgt atacgcgttg tgttttgtaa
     9361 gcttgtgaag aaacttccat cactagatga gtcataccat tttcaactgc ttctgacatc
     9421 atacgatata aatctaatga ctcaggcgtt gtcaaatggg atttgaaata tgttttgcca
     9481 tctaacgttg tattcatagt agaaagcaat gctgtttttt tatttgttgt gtgatccaag
     9541 attgcttttg taaagtacgc agcagttgtt ttaccttttg ttccagtgaa tccgatcact
     9601 ttcaatttat tttgcggata gtcgtaaaaa gccatagcaa gaagcgccat tgctttacgg
     9661 atatccgtta cgatgattcc tactgctgaa ttttcgtatg gttgttctga tacataatat
     9721 tgaataccct gttcgattgc tgaatccaaa tattcttctt tgaaattcat tcctttacag
     9781 aaaaacaaag tagaagcatc agcttttctt gaatcataac ttaactgaag aaattcagct
     9841 ttttctggta catcaagatg ccagcctctt gttgaaacaa attcttttaa tagattttct
     9901 tttaatagta aatgacggat gtcttctaaa gagaagctca ttgattgatc cctcgcttta
     9961 ttcaatttct tggtttatta tagcacactc tttttaatat atcgtttgtt tccgctatga
    10021 caaaatccag ctttattcaa attttcttga cacaggggac aagcggatga gtattttcat
    10081 aaacaatgaa ctgactgtaa tagataggag aacgaatagt gtctccaaca atccaaaaac
    10141 ataataattc aaaaagacga taagactatt ggtaagtaaa agtccttgcg gcattggaag
    10201 ccgaaaaaat ttgtggaaaa taatcggcgg tatcgttata ccgccatttg aggccccgac
    10261 tgtgtacaat gtgtaaaccc caagactgaa caaaagactt cctgaaatca gtgaaaagaa
    10321 atgtgaggag atcatttcca cttttggaac aatctctaaa acaacaggaa aaagcagact
    10381 tcccgctaca gtcttaaaaa atactgattt tcctaatagg acagcggcta gaagcagcat
    10441 cataagattg atgctccaaa cagtaactga gcgttggata gaaaaggccg tttcaactaa
    10501 atgtccgatg gcgcccactc cggcggaagc tatatcgtga gggagcaaga accaattcaa
    10561 tccaactgtg ataaagaaaa gacctaaaaa tataacgggt agttttttta tttcttgtgt
    10621 cattgatatc tcctataaat gttagccata aaaggctgta tatttcttta ctttaccaaa
    10681 aaaacgaaac cgaattcaaa aaaacaattg ttcttataaa agttatataa aatcgattgc
    10741 cagtttctgt tttaccaatt aaaatgatag taatgttttg tagaaagttg gaatctgacc
    10801 gatggataat caaagaaaac cagcattaga tcaattaaca ccgcaagaaa aaatggcacg
    10861 aggctctgct tggatgaccg ccagtaatat catttcaaga ttgctaggcg ctgtctatat
    10921 cattccctgg tatgcttgga tgggcgaaaa tgctaaggct gccaatggat tattcaatat
    10981 gggatacaat atatatgcat tgtttctact gatctctaca gcaggaatac ctgctgcgat
    11041 tgcaaaacaa actgcacgct ataattcatt gaatgaatat ggcacttcac gacgattatt
    11101 tatccgtgca ttacagatga tgggcgggtt aggcctgttg tttgctttgt tcatgtacat
    11161 cgcctctcct tggctagctc atgcttctgg tggcggagaa gaactgattc caacgatgcg
    11221 ttctttgagt atcgctgtat tggtttttcc ttgtatgagt gtgatacgag ggtatttgca
    11281 aggcaatcaa gaaatgatgc cttatgcgct gtcgcagatt gtagaacagg tggcacgtat
    11341 tttttatatg ctattggcta cattcatcat catgaaagtc atggatggtg actatgtgac
    11401 ggcggtcacg caatcaactt tcgcggcatt tatcggtatg ctagcaagta ttcttgtcct
    11461 tttgtatttt ttgaagaaac atcaagcgta tacatcggcg tttattcact acagcgaaaa
    11521 caaaataaat attgcaacga aggaattgtt gttagatacc gttaaagaag cgattccgtt
    11581 tattattgtg ggttcagggg taacgatctt caaattagtc gatcagttca cttttatgaa
    11641 gatcatgtct gcatccaccg agtattccaa tgcacagtta ctggatcttt tttcgatttt
    11701 tagtgccaat ccagataagt tgacgatggt agttattgca ttggcaacat cgatcgcgtc
    11761 tactgggtta ccgttgatta cagaagctgt tacgttgaaa gatcgagtag gtctggcaaa
    11821 attgacaagc ggaaatttac agttgttttc attttttatg tttccggcga catttggtgt
    11881 tatgttactt gcctatccgc taaatacatt attttataca ccggattctc taggaagtaa
    11941 tgtactgatc caagcaagtt ttgtaggact cttcctagga ctatatatgc tagtttccaa
    12001 catgctgcaa ggaatgtttg aaaacaaggc ggcaattaat tatttggtta ttgggtttct
    12061 agtgaaactc cttcttcaat acccagccat tcgtttattt gaagtatacg gccctttatt
    12121 ggcgacaatg atcggatttg ctgtgtcttg taccttgatc ttaaagagaa tccatgaagt
    12181 agcccgcttt aaaccaagtt ttgtctggcg caggacattg ctgatcttta ttcttacctt
    12241 gattatgctt ttggcttcgt ggatcacaaa gatgattttt ggtgcttttt taaacgaaga
    12301 tagcaaattc cagtctctat tgttgattct tgtagtagca ggtatagggg ctttagtgta
    12361 tggttattta gctttgaaaa tccgcttggc agaaagacta ctaggaccag gaatagcgcg
    12421 tttacgacat aaattaaaaa taaaataagt gaatcagaag agctagattg atgctctttt
    12481 gaaatggggg aaacgcatgc gtttagataa gtttttagca gatatgggac ttggcagccg
    12541 caaagaagtc aaaggattaa tcaaaaaagg aacgatcgaa gtcaatggac aagtggtgaa
    12601 aagcgataaa gcgcaagtaa atgaattcga agatgcggtt acttatttag gagaaatcat
    12661 tacgtatcaa aaagattttt actacatttt gcataaacct gcaggagtca tttctgctac
    12721 tcaggataat catgatcaaa ccgtaatcga tttattggaa gaccaggatt atcgggaaga
    12781 tctttttcca gtcggccgat tagataaaga cacagagggc ctcttgattt taacgaatga
    12841 cggggtgttt gcccatcagt tactatcacc taaaaaacat gtggagaaag aatatctagc
    12901 tgaggttagc ggtataatga cagaagaaga tatccgttta tttgcagaag gactgattat
    12961 tgatggcgat gagcagacat tgccggcaaa actccaaatt gatcaagtag atcaagagac
    13021 agaaacttca attatccgtc tgattttgca tgaaggaaag tttcaccaag ttaagcgaat
    13081 ggtcaaagca gtaggaaaag aagtcttata tttaaaaaga atccgtatgg gaaaattttg
    13141 gctgcctaaa gatttgaata aagggcaata tcgacccatg accaaagaag agctagaaca
    13201 agtgagagaa aaataattga atggatagct aaaagaataa gcagagtagt tgtagcgcca
    13261 tctgaaaagc agacttgtcc gtctgacttt cggatggctt ttttgtgaaa tttcggctta
    13321 tttccgtaga agctacttct ggaacaccgt ttgttcggaa taagggactg tgacaagact
    13381 tttgttacag tccccattgt tccttgtgac tcagagttag atagtaagga cacgatctcc
    13441 ctaatactca ggccaaaacg ctgaattcac aacctctgat aaacggtgtt caatcagctg
    13501 accctcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttccc gtttttttct
    13561 ctaatactca ggccaaaacg ctgatttcac aacctctcct atactttgtt tcattttccc
    13621 tatactttgt ttatttattc tcattattga aagcgctata attacgttgc gaatgaatcg
    13681 aaaggggttt ttagatgaaa aaacgaaagg ggttcaatca tttttttatg aatctatggc
    13741 gttataaagc acttgtcctg atggctgtac cgggtatgct ttggatgatt tttttctttt
    13801 acatacctgt aatggcgaat gtcgtagcat tcaaaaattt tcatatttca gcagatgggt
    13861 tcttggctag cttgagggaa agtccttggg tgggttggga aaatttcaaa tttttatttt
    13921 cttcggatca agcatttctc atcactaaaa atacaatttt atataatgta gcatttatcc
    13981 ttttgaatct gctgatctca gtcgtatttg caatcattat gagcgagttg agaaataaac
    14041 gactcgttaa agtttatcaa acgatgtcct tactacctta ttttctatct tgggtcatta
    14101 tcagttactt tgtttacgct tttttaagtc ctgacaaagg aatattcaat cagtggatca
    14161 ctggacatgg aggagaagct gtcaattggt ataatgaacc gaaatattgg ccgtttatct
    14221 tggtgttcat tggtacatgg aaagggattg gttataacag cattatttac tttgcatctg
    14281 ttatgggaat cgatccgact tattatgaag ctgctatggt tgatggagct agcaaatggc
    14341 agcagatcaa acatgtgacg ataccacaac ttattccact aatgacgatt ttaacgattt
    14401 tagccgtagg aaacattttc cgagctgatt ttggcctgtt ttataacatt cctaggaatt
    14461 ccggtgcatt atatgatgtg actcaagttt tggatacgta tatctacaat ggcctgacat
    14521 ccacaggaga ttttggtatg acggctgctg caggacttta ccaatcagtt gtcggctttg
    14581 tcttgttgat gatcacaaat acgatcgccc gacgttttga tagcgattct gcattattct
    14641 aaggaggaaa aaaatgaaaa aaaagaaagt ggagagagtc caagtccgct ctttcaataa
    14701 gacggctaat tttttctcta atataatgat tgcactcttt gctatttcct gtattttgcc
    14761 atttatattt gttatcgcca tctcttttac cgatgagtcc atattgtcga ctcacgggta
    14821 cagtttttgg ccagaaaagt tcagtatatt tggttatacg tacttgttcg accagatgca
    14881 ggataaaatt ttccaagcgc ttttcgtcac tgtacttgtt actgttttag gtacactgat
    14941 caatagcacg gctacttctt tatatgctta tgcgatttca cggtcaaact ttccattccg
    15001 tcgttttttt accgtttttt gtttgattac gatgttgttc tcaccaggga tggtggccaa
    15061 ttatcttgtt atgacaaatc ttcttcagtt aaaagatacg atttgggcat tgatcttgcc
    15121 aatggctgtc agtcccttca atattattgt gatgcgcaca ttctttaaac gttcggtctc
    15181 tgattcgatt attgaatcgg cacggatcga tggagctagc gaactgcgaa tatttgttca
    15241 gatcgtttta ccgttagctg ttccaggtat tgcgacaatc agtttatttg ccgcattggg
    15301 ttactggaat gactggttca atgctttact atacatccaa gatgataagc tagttccact
    15361 acagtatctt ttgatgaaaa tccaaagtaa tattcaatat ctgacacaaa attcaggagc
    15421 aggaagccaa ttgacaggcg gattagcctc agttccagga gaatctgcca gaatggcgat
    15481 cgtagtcatc tcgacgttgc ctattgcgat cagctatcca tttttccaga agcattttgt
    15541 caaaggtcta acaatcggcg gagtaaaaga ataaagaaac aaaaatataa atcataaaat
    15601 taggaggaag aaaaatgaag ttatggaaga aactagcctt tacaggtgtt tcagcgttgt
    15661 tgttgggaac attagcagca tgcggaggtt ctggttctaa agaccaggca gaagctagca
    15721 attcggacac tttgcagatg tatcaaatcg gagataaacc agataatttc gatcaattga
    15781 tggaagtagc aaacaaacga atcgaaaaag agatcggtgt aaaagtcaat atcaattaca
    15841 ttggctgggg cgattacgaa aagaaaatga acgtcatcat ttcttccggg gaaaattatg
    15901 atatcgcctt tgcgaacaac tatgtttcca atgcccaaaa aggagccttt gctgatttga
    15961 ctgaattagc gcctaagtac gctgaaaaag cttataatga tttagatgaa gcatatatta
    16021 aaggaaatct ggtcaatgga aaattatatg ctttcccagt caatggaaat gtctttgctc
    16081 aacaagtact tacttttaac aaagctttac tagataaata cgatctttca attgatggaa
    16141 tccaatctta cgctgatgca gaaaaagtct tgaaggaatt ccatgaaaaa gaaccaaaca
    16201 cggcagcttt tgccattgga caaggcttca aagtccaagg gaactttgat tatcctttag
    16261 ggaatacgtt accatttgct attgatctgg atggagatga ttcgaaaatc atcaaccaat
    16321 acgataatga aacgtatatc ggactgttac gtacaatgca tagctggtac aaacaaggac
    16381 tcattccaag tgacgctgca acgagcaata aggattatcc actagaagga aatacttggc
    16441 taatgcgtgg agaaacacaa ggaccgtatg attatggcga tacaattttg acaaatgcag
    16501 caaaacaaga acttgtctca aaagcaatta ctgttccact aaaatctaca gctcaagcac
    16561 aaatggcaaa ttttgtcgta tcaaatactt caaaaaataa agaaaaatca gtagaacttc
    16621 tagggctgct taacagtgat ccagaattat tgaatgggct tgtttggggg atcgagggag
    16681 aagcatggga aaaagtcgat ggttcagatg ataaaatcaa attgctagat ggttatcagc
    16741 caaatacaca tatgtctgct tggaatacag gaaacaacaa gattctatat acacaagagt
    16801 ctattacgga tgacatgatt gccaaacgtg atcaatcgat tgctgatgca gaaacttcac
    16861 cgattttagg attcagcttc aacactgaca gtgtcaaaac agaattaagt aatatttcta
    16921 atgtcatgaa tcaatattta gatggattga atacagggac tgttgatcca gatgaaacat
    16981 taccgaaatt gaaagacgct ttggacaagg ctggctatga taaggtattg aaagaaatgc
    17041 aaaaacaata tgatgagttc cgacaagaat aataatgaat aaagacaaag gggttgtgac
    17101 aaaagacgtg tcacaacctc ttgttccgaa taaacggtgt tcaaaagcca gtttctcggt
    17161 attaagctaa atatatgtaa aaatgtggaa agccatattc acaaaatttt tcttactact
    17221 cgaaactaag cggctatttc acaaactctt ggtaaacggt gttcaatcag ctaaccctcg
    17281 gtattcgctc acaaaacgac aaaatatgag gaactatttt tccgtttgtt tctctaataa
    17341 tcaggtcaag gtgctgattg cccaaccttt ttttgtataa tgagaaagta taaacttaat
    17401 gtttggagga gaagatatgt tagggaaggt tttggaagag ttatttatcc ggatctgggt
    17461 cattataaaa ctaaccttgt atttctggat atatacattt gccggcggga tcatctttgg
    17521 attaggtgcg gcatggaaaa cagtcaatga actattttat ttgtacggat tcgagtataa
    17581 agaaatcaca ataaaaagag gctggaatat atataaaaga aattttttaa gaggcaatct
    17641 gctatttagt ttatttttat ctggtactgc tttattgagt tacaatttat atttatctgt
    17701 tcaaatcaaa gggctcattt ttttagctat tgattttatt ttactttttg ccttgctctg
    17761 cctatttgct acttatcaat acagtatgat tttagatagt gaatatacga tctctgttcc
    17821 taatctgcta aagctaagtt ttatttcggt tttttccagc ttttcgtctt ttctaaaaat
    17881 aattattggt agcggtataa ttttaggcgt gacttggcaa ttcaaaggat tgatcctgtt
    17941 tggtgtcatt ggtcttttga cggtttggaa tggtacgatg acaacacatt ggcgtgaaga
    18001 attagataaa cagttggaaa gttatgaata agtttcggat tctattttca aaaggaacct
    18061 tactaaatcg tctgttgcgg aaatacgcgg ttatcatgat cggtgtaacg atgactgcta
    18121 ccgttatttt tagtatccat acttgggaac aaaatcaaaa acaggcagaa aacatgacaa
    18181 gtgatgccgt tcaaagcaca agcagaatgc tgaatgataa aacaaccttg agtaggatca
    18241 tcaaaaacca gcttgtaggg aattccgaaa agatcgaaaa tgtgacgacc tacttaacaa
    18301 aacccataga tcagtatctg atgtatgtat acgaacagca aaacagtacc gatgaattag
    18361 tttctttccc aaatcaaatc aaagatctct acgcaaatta tgaagaacta agtgcgatat
    18421 atatcgtgtt gaatcaacta ccggagtatt atgaatcttc tagagaaaac aaaggtgggg
    18481 aaataaaaaa ggggacacca aaattactag acgcctttta tatcaagttg cctatcacac
    18541 aaggaggagc tgagtcagga agtattttta ttggttttca aaagaaagaa ctagatatga
    18601 ttttagaaaa tctaacgtca ttcaatggac tctctttata catgatttct ggaacgacaa
    18661 atcgactata cacattccat gataataaaa tagctaaaga aacgtttgaa agacaagaaa
    18721 tgatcatcac agagagtctg aagaaaaatt cacaattgcc gattgacgat ctggaaaaaa
    18781 acaattttgt tcaacaccaa gaactgtctg atgattatcg tatattagct gtactagata
    18841 aaaaaagtgt aaaaatcgaa acgggaaaaa atcttgcccc gctgatcatt ggtatcatta
    18901 ttttagacaa tatactgctt atctttcttt ataaaacatt caaacgatat tcacagcaag
    18961 tatctatcgt catgcaggcc atggatcaaa cagcagcagg gaatttagag acgcggatcg
    19021 acataacaaa cacggaatat gaactgaagg aactttcaat cggtatcaac gaaatgttgg
    19081 atagcatcaa tcagtttgta gaagacatct acaaattaga aatcaaacag caagacgcac
    19141 atatgcgggc gcttcaagca cagatcaatc cacacttttt atataataca ttagaatata
    19201 tccgaatgta tgcaatcagc gaaggaagtg aagaattagc agatgttgtg tatgcgtttt
    19261 ccgctttgct tcgaaacaat acgaatcaag agaaaacgat cactttaaaa gaagaactgg
    19321 acttttgcga aaaatatgtc tatttgtatc aaatgcgtta tcctaatcga gtagcctatc
    19381 attttatgat cgatcctgat ttggaaaaga tcgaagtacc taaatttgtg atccagccat
    19441 tagttgaaaa ttattttaaa cacggtattg attttactcg attcgataat gcgctaagtg
    19501 tcaaagtctt gcaggaaggc aaacgggtaa ggatcatcat caaagataat ggaaaaggga
    19561 tgactgaaaa acggctaaaa cagattgaag aaaaactgtc tcatcctaaa gtggaacttc
    19621 acggttctat cggtctgcaa aacgtgaatg aacgtttacg tgccagcttc ggcagcagtt
    19681 attatatgtc gcttgagaat aatgagacag gtggactgac cgtttctatt acattcaagg
    19741 agggatgagc gtgtatcaag tgttattggt agatgatgaa tacatgattt tgaatgggtt
    19801 aaaaaagata attgattggc aaagtttagg ctttcaaata gtagcaacag cagagaatgc
    19861 caaagaagga ctagctgtac ttgaacagcg acagattgat ttagtagtaa cggatgtgac
    19921 aatgccagaa ataaatggac tggaatttat tgaagcggct caaaaagaac gtcataattt
    19981 tgaatttatg attttatcag gataccaaga attcgattat ttgaaaggag gtatgcaatt
    20041 aggcgccgtg aattatttga tgaaacccgt gaataagttc gaattggttg aaagcctcaa
    20101 gaaaatcaaa acacggttag atcagcaaaa tgaacaaaaa aatcaacaag aaatctatca
    20161 agaactgtta ttcagtcaat ggttgaatga agaattggat gaaataagtg aagaagaaat
    20221 aataggacaa ataagtgaga agcagcatag gatagtattg attcaactgg caagaactca
    20281 tgatactctt atcaatagat ggttgcaaga acggcaacaa atcttttact atcaacgaaa
    20341 ttacggagac cgtgtattga tcacgttgtt gttggaggca gatgaagttg atggcttctg
    20401 ttgttttgtt caagaaaact ttcctgatca ggaatggctg atcagtatcg gggaagagac
    20461 agattctttg gacaaaatcc ctgaaacatt ccaacaagcg aaagacaatc tacagttgca
    20521 tcaattttat ggagataaag acgagcatgt tttttacgca gtacaagcag aaacaaaaga
    20581 tcaaaccatc gatttttcaa gtttcagacg cgtgctgcaa aataaacaat tggaagtcgc
    20641 tcaaaaaatg atcactgatt tttttgaaca gtttcagtta gcagccatga tgccggaaga
    20701 tatacgatat tccagttttt tactgtttat ggagattcaa cgggaattga ttgatctgga
    20761 agatgaggaa tatttacaag gaatcgaaaa aatccatcag gcaaaaacgg tgcaagaact
    20821 tcagcagcta cttctgtcat tcatcaaaaa gcatcagaga cagaaaaagt acagtgacaa
    20881 tgtggaaaaa gtaatcgtaa tcctgcacca gcattatcaa gaaccactta cactcaaaga
    20941 agtgtcagaa aacctgcatt taaatgtcat gtatctagga cagctgttca aaaaagaaac
    21001 gaaaaaaagt ttttcagctt atttgaacca tttacgtatg gaaaaagcga aacaactgct
    21061 tttgcacagt aatcaaaaca tcaatgagat agcaagtgag attggctaca acaacaccac
    21121 gtatttctct aaattattca agaaaatcgt cggcagatcc cctaaagagt accgagaaaa
    21181 cagtggagaa tcataaaaga aaaagccaat gtaatgaaat aacttataaa aaattgtcta
    21241 gaaatctaat tttgggctgt tcttattact tgaggcaagg cagctttttc atgacctctc
    21301 gataaacgga gttcaaaagc cagtttctcg gtattaagcc aaatttatgc aaaaatgtgg
    21361 aaagccattt tcacaaaatt tttcttaata ctcgaaacta aacagctttt tcacgacctc
    21421 tccactaaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaat ggcaaaatat
    21481 gaggaactat tttgccattt gtctctctaa tactcaggtc agaacgctga tttcacaacc
    21541 tctcaataaa cggtgttcaa aagcttgcat ctgcggtaat aagaccaacc aaacgaaaaa
    21601 tatgaggatc tattttt
//
LOCUS       DAPBCF010000044        21594 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.045, whole genome shotgun sequence.
ACCESSION   DAPBCF010000044 DAPBCF010000000
VERSION     DAPBCF010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.045"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            177..404
                     /locus_tag="RD508_002054"
     CDS             177..404
                     /locus_tag="RD508_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDT7736607.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            420..1586
                     /locus_tag="RD508_002055"
     CDS             420..1586
                     /locus_tag="RD508_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDT7736608.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            1821..2864
                     /gene="hrcA"
                     /locus_tag="RD508_002056"
     CDS             1821..2864
                     /gene="hrcA"
                     /locus_tag="RD508_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HDT7736609.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            2958..3521
                     /gene="grpE"
                     /locus_tag="RD508_002057"
     CDS             2958..3521
                     /gene="grpE"
                     /locus_tag="RD508_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDT7736610.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDRYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            3572..5401
                     /gene="dnaK"
                     /locus_tag="RD508_002058"
     CDS             3572..5401
                     /gene="dnaK"
                     /locus_tag="RD508_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDT7736611.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            5552..6718
                     /gene="dnaJ"
                     /locus_tag="RD508_002059"
     CDS             5552..6718
                     /gene="dnaJ"
                     /locus_tag="RD508_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDT7736612.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(7086..7823)
                     /locus_tag="RD508_002060"
     CDS             complement(7086..7823)
                     /locus_tag="RD508_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7736613.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(7825..9327)
                     /locus_tag="RD508_002061"
     CDS             complement(7825..9327)
                     /locus_tag="RD508_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HDT7736614.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIEKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            9586..11580
                     /gene="uvrB"
                     /locus_tag="RD508_002062"
     CDS             9586..11580
                     /gene="uvrB"
                     /locus_tag="RD508_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HDT7736615.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            11590..14406
                     /gene="uvrA"
                     /locus_tag="RD508_002063"
     CDS             11590..14406
                     /gene="uvrA"
                     /locus_tag="RD508_002063"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDT7736616.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            14669..15934
                     /locus_tag="RD508_002064"
     CDS             14669..15934
                     /locus_tag="RD508_002064"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HDT7736617.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            15938..16669
                     /locus_tag="RD508_002065"
     CDS             15938..16669
                     /locus_tag="RD508_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HDT7736618.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            16804..17688
                     /gene="rapZ"
                     /locus_tag="RD508_002066"
     CDS             16804..17688
                     /gene="rapZ"
                     /locus_tag="RD508_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDT7736619.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            17685..18683
                     /locus_tag="RD508_002067"
     CDS             17685..18683
                     /locus_tag="RD508_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HDT7736620.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            18717..19652
                     /gene="whiA"
                     /locus_tag="RD508_002068"
     CDS             18717..19652
                     /gene="whiA"
                     /locus_tag="RD508_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HDT7736621.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            20195..20845
                     /locus_tag="RD508_002069"
     CDS             20195..20845
                     /locus_tag="RD508_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736622.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            21032..>21594
                     /locus_tag="RD508_002070"
     CDS             21032..>21594
                     /locus_tag="RD508_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HDT7736623.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT         7103 a         3658 c         4712 g         6121 t
ORIGIN      
        1 ttttttatga ataaaataag gacaaaattg tttaggaaga atcatgagtg taaaaaaatc
       61 atccaagaag tcgattcttg gattttttag tggatttgtt cgccaaatac gtttagtatg
      121 cgtatatgag aggttgtaag caaagcgttg tggtctgagc acttaaggag gaatctgtga
      181 aaatagcttt tcatattttt gcagattttg acttaatgcc gaaggtcagc tttgcgatta
      241 ccgtttatcg agaggctgta aaagcaccgt gtagctccga tgacaataag caagcatttt
      301 tagagctagg tttccttgat tctaaatatg cggcttattt caatgagttg gtgcttgaac
      361 gcgattttaa gaaggtcgaa aacaggcacg acttttcgac gtaaggagaa agaatttcaa
      421 tgatagaaac aataaatccc gcagaaaaca aggtttctgc gtacattcat atcccatttt
      481 gcgagcatat ctgctattac tgtgacttta ataaagtttt tttagaaggg cagccagtag
      541 atgagtatgt ggaaatgctg ctgaatgaaa tgagattaat gctggaaagt catcctacag
      601 cgaatttgga aacactttat gtaggaggcg gaacaccaac ttctttatct gctaaacaac
      661 ttgatcgact attatcaggt gctagagaga tcctgccttt tcaaaatggt aatgagttta
      721 ctgtagaagc gaatcctggt gatttgaccc gtgaaaaact tcaagtgatg aaaaactatg
      781 gcgtcaatcg tttatccatg ggagtgcaga catttgacaa tcgcttattg aaaaaaattg
      841 gacgtaaaca tactgcagaa gatgtgtatc aaacaatgca atttttagaa gcagaaaatt
      901 ttaccaatgt aagcatcgat ttgatttatg cattaccggg acaaacacta gaaggatatc
      961 gggatacttt ggaaaaagct ttggctttgg atctgcctca ctattctttg tactcattga
     1021 tcctcgaaaa caaaacaatg ttcatgaact gggtacgaca aggaagactc gaactgcctg
     1081 atcaggaaac ggaaaccaga atgtttgaag agacgattga agcaatggaa aagcatggac
     1141 gtcaccaata tgaaataagt aactttgggc tctccggaca tgaatctcaa cataacctca
     1201 tgtactggaa caatgaccac tattttgggt ttggagctgg tgctagcggt tatcttggag
     1261 atattcgtta ccgcaacaaa ggaccgatcc aacactattt acgcccatta cgagcaaatg
     1321 aacgcccggt attggaagaa gaaaaattga cacgaaaaaa tcaaatagaa gaagaaatgt
     1381 tcttaggact aagaaaaaaa acagggatta ctaaaaaaca tttctatgat cgctatcaaa
     1441 aaacaattga atcggtgtac ggtgatgtgc taagggaatt agagcaagaa gggttacttg
     1501 ttaatgaaga agaccgtgtt tatttgacac caagagggac ttttttgggg aacaatgtgt
     1561 ttgagcgctt tttatttgaa aaatagtttg aagaatattt gttttttatc gaaacttgaa
     1621 aagaaaaagt ttagaaagtt tgacaatgag gtattgaagt attgatataa ctggatttac
     1681 atcaattatt tagaattagc actcttgtgt ttagagtgct aaaaaatgga gtctttctct
     1741 tgacaggaga agggcttctt gctatattta taagtgaatt agcacttaga atatatgagt
     1801 gctaatgaga ggtgaggaag atgttaacaa agcgacaaaa cgacatttta cgtctgatca
     1861 tccaacacta tacgagtagt ggcgtgcccg ttggttccaa aacattaatg tctgagggag
     1921 tcaaggccag ctcagcaacg attcgcaatg atatgaaagc attagaagat gaaggattgc
     1981 tgttgaagac tcactcttct tctgggcgga ttccatctgc tttaggctat cgttattacg
     2041 tggatcattt gttaaaacct gctcgcgtag cagaagatga tttgctgctg attcgtcagt
     2101 ctctaggcag agaatttcat gaaatcaatg agattattaa gcaatctgct gagatattat
     2161 ctgagctgac aagctatacg actttttcat tgggacctga aataaaagac cgccgactga
     2221 ctggctttcg tatcgtaccc ttgaataatc gacagattat tgctatcgtc gtaacagata
     2281 tggggaatgt agaaagccaa gtgttcactc ttcccgaata tatgggaagt caggaactag
     2341 aaaaaatggt acagattgta aacgaccgtc tagtcggaga tcctctgatg acggtgtacc
     2401 ataaacttcg tacggagatt ccgatgattc ttcataaata tttccagacg acagaaggga
     2461 tgtctcagtt atttgacacc gttcttggtc atgtttttga agaaaaggtt tatgtcagtg
     2521 gacaaatgaa tctcttggat tatgagcccc gtcaagatct tgatcagttc aaatcgatgt
     2581 tttcttttat gaaagactca gacggactta cacaaatgat cactccgatg gatagcaata
     2641 ttcatatcaa gattggtgct gaattaggca atgatttatt gcagaatatg agtatgattc
     2701 aagcaagtta cgagatagat ggtcatggaa gaggtacaat agccttgtta gggcctacta
     2761 gtatgcctta ttctcggatg ttcggtctag tcgatgttta tcgaagagaa ctagcagcta
     2821 aacttgctga ttattaccgc tcgcttgact tgtcaaactc gtaatgtgaa taacgaagct
     2881 atttgcagct gatcgttctc tctttcttag taagagcaat caaacagctg actgaataat
     2941 gaaaggaaga ctgtatcgtg aaagaaaatc aagaagaact agataaagaa atgacagatg
     3001 ctcagccaga accggaaatc gatgtcgaag ctgcagaaga ttcgggtatt tcagaagctg
     3061 aagcggaaga attcgaaaca gcgaaattaa aagctgagtt agaagaaatg gaagatagat
     3121 acttgcgggc tcgtgctgaa atcgcaaata tggcaaatcg aggaaaaaat gagcgtgagc
     3181 aattacaaaa ataccgttca caagatttag ccaaaaaatt acttccatca attgacaacc
     3241 tggaacgtgc attagccaca gaagtgtcag atgatcaagg ggcaggtttg aaaaaaggcg
     3301 tggaaatggt cttggaaagt ttgcgtaacg cactggaaga agaaggaatt gaaaaaatcc
     3361 ctgctaaagg agaagccttt gatcctaatc ttcatcaagc agtacaaact gttccagcga
     3421 ctgaagatac accagccgat acgattgtag aagtactaca agaaggctac aaattacatg
     3481 atcgcgtgtt aagaccaact atggtcattg ttgcacaata attgtgcgga tataaaactt
     3541 acactttcaa ttaaagaagg agacgttaat tatgagtaaa attatcggta ttgacttagg
     3601 tacgactaac tctgcagtag cagtattgga aggaaacgaa gcaaaaatca tcgctaaccc
     3661 agaaggaaac cgtacaacac cttctgttgt atcattcaaa aatggagaaa tccaagtagg
     3721 ggaagttgca aaacgtcaag ctgtgacaaa cccaaatacg atttcatcaa tcaaacgcca
     3781 tatcggtgaa gcaggttaca aagtagatgt agaaggtaaa tcatatacac cacaagaaat
     3841 ctcagcaatg atccttcaat atatcaaagg attcgcagaa gactatttag gtgaaaaagt
     3901 cgaaaaagca gttatcactg tgccagctta ctttaatgat gcacaacgtc aagcaacaaa
     3961 agatgctggt aagatcgctg gtctagaagt agaacgtatc gtcaatgaac caactgcagc
     4021 tgctcttgcc tatggtttag ataaaacaga tcgcgacgaa aaaatcttag tattcgacct
     4081 tggtggcggt acttttgacg tatctatcct tgaactagga gacggtgtct ttgatgtatt
     4141 gtcaacagct ggcgacaacc atctaggtgg ggacgacttt gataacaaaa tcatcgacta
     4201 catggtagca gaattcaaaa aagaaaacag cattgacttg tctcaagaca aaatggcttt
     4261 acaacgcttg aaagacgctg ctgaaaaagc gaaaaaagat ttatctggcg tatcaagcac
     4321 acaaatcagc ttgccattta tcacagcagg agaatctgga ccattgcatt tggaaatgac
     4381 attgacacgt gcaaaatttg atgaattaac agctgactta gtagaacgta caaaagtacc
     4441 agtacgtcaa gcgttaaaag atgcaggtct gtcacaatca gaaatcgacg aagttatttt
     4501 agtcggtgga tctactcgta tccctgcagt tgtagaagca gtacgtaaag aaacaggaaa
     4561 agaaccaaac aaatcagtta accctgatga agtagttgct atgggtgctg ctatccaagg
     4621 tggcgtgatc actggtgatg tgaaagatgt tgttttactt gacgttacac cattgtcatt
     4681 aggtatcgaa acaatgggtg gagtgttcac taaattgatt gaccgcaata caacgattcc
     4741 aacaagtaaa tcacaagtat tctcaactgc ggcagataat caaccagcag tagacatcca
     4801 tgtattacaa ggtgaacgcc caatggctgc tgacaacaaa actctaggaa gattccaatt
     4861 gacagatatt ccagcagctc ctcgtggtat tccacaaatc gaagtaacat tcgatattga
     4921 taaaaacggg attgtaaatg tatctgcgaa agatctaggt acacaaaaag aacaaaaaat
     4981 cacgatcaaa tcttcttcag gtctaacaga tgaagaaatc gaacgtatgg tgaaagatgc
     5041 agaagcaaac gctgaagcag ataaagctcg taaagaggaa gttgacctac gtaatgatgt
     5101 agacgcattg ctattctctg tggacaaaac attgaaagaa ttagaaggca aagtggacga
     5161 agaagaagtg aaaaaagcag aaacagctcg tgacgaatta aaagccgctg ttgaagcaaa
     5221 caacatcgag gaaatgaaaa ctaaacgcga tgcattgaac gaaatcgttc aaaacttgac
     5281 tgttaaacta tacgaacaag ctgcacaaca acaagctcaa gaaaatccag aagcagctca
     5341 aggcggagca gatgatgtcg ttgatgctga ttttgaagaa gtcgatggcg acgataaata
     5401 atcagttcac tgaatttcga gagaaggcca aagttgctac tttggctttt tcttttgaaa
     5461 aatagtttga agtatcggtt tttgtttcaa acaaaatatg atatgataac aagcgacgtg
     5521 aaaatgatga gaaccaatag gaggaaagcc tatggcaaca aaacgtgatt attatgaagt
     5581 cttagggctc tcaaaaggag catcagaaga tgaaataaag aaagcttatc gtaagctttc
     5641 gaaaaaatac catcctgaca tcaataaaga acctgatgcg gaagaaaaat tcaaagaagt
     5701 atcagaagca tatgagattt taagtgaccc gcaaaaacgc gctgcatacg accaatacgg
     5761 gcatgcaggc acagatccaa attacggtgc tggtggagct ggtggcggat ttggtggatt
     5821 cggcggcttc tctggtggcg gcttcggtgg ttttgaagat atcttcgact ctttctttgg
     5881 aggaggcggt cgatcagtcg atccaaatgc gcctcgtcaa ggtgctgatt tgcaatatac
     5941 ggtcgacttg tcttttgaag aagcgatttt tggtgtagaa aaagaaatca agtataatcg
     6001 ggaagaaatc tgtcatactt gtggtggaaa cggtgcaaaa ccaggcacac aaccaactac
     6061 ttgtcataaa tgtcatggtg caggtacgat caatgtagaa cgccaaacgc cacttggacg
     6121 agtgatgagc cgtcaaactt gtgatgtttg tcatggcaca gggaaagaaa tcaaagaacc
     6181 ttgtccaacc tgtcatggct caggacatga gaagaaagca cattcagtta aagtgaatgt
     6241 accagctggt gtagaagaag gacaacaaat gcgtttagct ggtcaaggag aagctggaga
     6301 aaacggcgga ccatttggtg atttgtatgt ggtctttcgt gtagaagaaa gtgatatctt
     6361 tgatcgtgaa ggttctgaaa tttactatga attgccttta agttttgtac aagcagcttt
     6421 gggggatgaa gtccaagtac caactgtcca tggagatgtg aaattgaaga tccctgctgg
     6481 aacacagaca ggtacgaact tccgtttacg tggaaaaggc gctccgaagt tacgtggtgg
     6541 tgcaacaggc gaccaacatg tcaaagtaaa actgatcaca ccgaaaaatc taaatgaaca
     6601 acaaagagaa gcattacgtg cattcgctga agctggcggc atcaaagttg aagaacagca
     6661 agaagacggt ttcttcgata agtttaaaga tgcttttggc gggaaaaagc ggaagtagtt
     6721 tttctagtaa aaatataaag tagacttgcc caaattttct atttctagta aaaacgctaa
     6781 gtcattaata attaaaaacc agacgaacaa tcatacgttc gcctggtttt tttgtagttg
     6841 tcatgtttgt accaacaaaa aagccagctt tagaataaga taatcatcat agtttctgaa
     6901 ggtggtatcg actatgtact tgatatcgtc aatgaaccga tggtactttc ttatgcgatg
     6961 gaacaggtag agcgattgct tgtttgtgca ggagaacaag cgatgcggct ggtacagtta
     7021 agtgaaaaaa caagaaacta aaaatgcccg gtcgtcatga agcaaccggg catttttggt
     7081 ttttattaaa tattcaatac tttattcaag aaatcttttg tccgttcatt ttgcggattt
     7141 tcaaagattt gttgaggcgt tccgtcttct aaaaagtttc cgtcgtcaat gaacatgaca
     7201 cgattggcca cttctttagc gaagcccatt tcgtgcgtaa cgataaccat cgtcatacct
     7261 tgttctgcta actttttcat gacgttcaag acatcaccga ccatttcggg gtcgagtgca
     7321 gatgtaggct catcaaaaag catgatgtca gggttcatcg ctagagcacg agcaatagcc
     7381 acacgctgtt tttgtccacc agaaagcatt tcaggataca tatctttttt atcttctaga
     7441 ccaactgtct gcagtaattt gattgctttt ttctctgctt cttctctaga ttctttcttc
     7501 aggtccatcg gtgctaaaat gatgttttcc aaaatagaaa gatgagggaa taggttaaag
     7561 tgctggaata ccattccgat atgttgtctc accaagttga tatctgtgct tttatccatc
     7621 aagtgggcgc cgtcaataat aatttcaccg tcagaaggtt cttctaaacg attcaagcaa
     7681 cgcaaaaatg tactttttcc tgaacctgaa gggccaatga tacagacgac atctccttcg
     7741 ttgatggata cattgatgtc gtttaatact gtgttatcgc cgtatttttt gactaaatgc
     7801 tcaactaaga ttttttctgc catcttactt caccttcttt tctaaaactt ttgctaattt
     7861 tgtcaatgct gtgatcaaaa tcaagtacat gatcgcaatg atcaagtaaa catacgtact
     7921 ttgtgttgta cgtgcaacaa tgatcttacc agtttgcagc aattcgacta caccgattgc
     7981 ggaaatgatc gttgtgtctt ttaatgagat aacgaactga ttgacgaatg atgggatcat
     8041 gatgcgtatt gcttgtggca aaatgatttt ttgcattgtc cgattataag aaagacctaa
     8101 acttctggaa gcttccattt gtccgacagg aacggcgttg atcccgcctc gaacaatctc
     8161 tgcgatataa gcacttgcgt taagagtcaa ggtgataaca ccagcaagga agtcaggaat
     8221 cgtaaatcca acgataccag gcaacccaaa gaaaataaag aacgcaagaa ccatcattgg
     8281 aattcctcgg atgatatcga cataaatact agcaattgtg cgaagagcgc gtattggtgc
     8341 tacactgaat aatccaaaaa tcacaccgat tactatagcc aaagcaaagg agatcaaagt
     8401 taggagaatt gttctccaaa gtcctttcaa caatgcttga tagttgtttt ggataagtcc
     8461 aagaaatgtt gattcatcag cagtggaaga ctcactagaa gtttctgaac catccgctac
     8521 atattctttg ataatcttat cgtattcgcc tgttcttttt aattctttca atccttcatt
     8581 gaacatatta agaagctcag gattttgtcc ttttttaacg gcaaatgcat attttccgcc
     8641 agattctttt tcgatcggtg tttccaattc ttgtccttgt ttgatcgcat aaccgattac
     8701 cggataatca tccatcattg catcgattgc gccaactttt aacccgtcgt acaattgatc
     8761 agcagcatca aaatatttga tagaatagcc atattcagat tcatggtcgc ttaaaaattc
     8821 agcactttcg gtaccaactt ttgctccgac tgtttttcct ttcaaatctt cataagactt
     8881 gatcgaagta tctccttttt tgacagctaa ttggatcccg ctatcaaagt aagaatcaga
     8941 aaaatcatag cttttctttc gttcatctgt tacagtcatt ccggcaatca ttccgtctgc
     9001 ttgtcctgat tccaaagctt gcaaagcagc agagaaacca cggtagtcca ttcggatgtt
     9061 aaatccttgc agtttggcga tgttttccat caattttaca tcgatgcctt cgtactcgcc
     9121 ctttgcgttt tgaaattcaa atggagcaaa agcagagtca ctggcaatta cgtatacgtc
     9181 ttttttgggc tctatttttt gcattgtctc gcttgtgctt gactctgccg ttgtagtgtt
     9241 gtcagcttgt gcaacatgac caaacgcaag tgtcacaagt cctgtcatta agaaaacaaa
     9301 tgagtgaaat aaatgctttc ttttcataat caacctccta aatttccaat attttattat
     9361 tataggcgaa aagtgctgaa tcagacaaga ctgtaagctc gaaaaaatga aaaaaatgcg
     9421 agtttctaac attttatgtt ataaaacgta acatgtataa taagataaaa aagtggcgaa
     9481 agtatgttcg gtgtggtata attttttagt aaggaatgcc tttgctttcc ttttcttttt
     9541 attggtcgta aaatgaaaag gaatgaatga aaaggaggac gaagaatgat tgagagagat
     9601 acctcccgac actttgagct tgtctcgaaa taccaaccgg ctggtgatca gcctgaagcg
     9661 attaaccaat tagtggatgg cgtagtcggc gggaaaaaag cacaaatctt attaggtgcg
     9721 actggaacag ggaaaacata tacgatttcc aatcttattg agaaagtgaa taaaccaaca
     9781 ctgattattg ctcataataa aacattggct ggtcagctgt acggggaatt caaggaattt
     9841 ttccctaaca atgctgttga atattttgtt tcttattatg attattatca gcctgaagct
     9901 tatgtgcctt caagcgatac gtatatcgaa aaagattcaa gtgtaaatga tgagatcgac
     9961 aaattacgac attcggctac tagttcatta ttagaaagaa atgatgtgat cgtcattgca
    10021 tccgtttcat gtatttttgg attaggttcg ccttttgagt accaaaaaca agtagtttcg
    10081 attcgacagg gagcagaact agatcgcaat cagttgattc gtgacttagt cagtatccaa
    10141 ttcgaaagaa atgatataga ttttcagcgc ggtcgttttc gagtgcgcgg tgatgtcgtg
    10201 gagatttttc cggcttcaag agatgaacgt gccttacgtg tggagttttt tggagatgag
    10261 gtcgaacgta tccgagaagt caatgcactg acaggtgaag ttttaggaga aacggaacac
    10321 gtggcaatct tcccggcgac tcactttgtg acgaatgatg aacatatgga gcatgccgta
    10381 gcgaatatca aagcggaatt agaacagcgt ttaactgtct tgcgaaatga aaacaaactt
    10441 ctggaagctc aacgtttaga acagcgaacc aattacgata ttgaaatgat gttagaaatg
    10501 ggctacacgt cgggaattga aaattattct cggcatatgg acggacgtaa agaaggtgaa
    10561 ccgccttata cgctattgga tttctttcct gaagattttt tgatcgtggc ggacgaatcg
    10621 cacgtaacca tgcctcaaat cagaggaatg tataatggtg accgagcgag aaaacagatg
    10681 ctagtagatt acggtttccg tttgccatct gctttagaca atcggccact tcggttagaa
    10741 gagtttgaaa aacatgtcaa tcagatcatt tatgtctctg cgacgccagg accatatgaa
    10801 catgaacaaa cagataccgt tatccaacaa atcatccgtc cgacagggct gcttgaccca
    10861 gtgatcgaag ttcgtccaat catgggacaa atcgatgatc tagtaggcga aataaatgaa
    10921 cgagtcgaaa aagaccagcg ggtgtttgta acgacattga cgaaaaaaat ggcagaagac
    10981 ctcacagatt atttcaaaga attagggatc aaagtcaaat atttgcatag tgatatcaaa
    11041 acgctggaac gaacagaaat cattcgagat cttcgattag gtgaatttga tgtgttagtt
    11101 ggaatcaatt tgcttcgtga aggattagac gtacctgaag tttcccttgt tgctatcttg
    11161 gatgcggata aagaaggctt tttacgtagt gaacgttcct tagtccaaac gattggacga
    11221 gctgctcgga atgaagaagg taaagtaatc atgtacgcag acaaagtaac agattctatg
    11281 cgtctagcga tggatgaaac gtcaagacgt cgtacgattc agcagaagta caatgaagaa
    11341 catgggatcg ttccaaaaac gatcattaaa gaaatccgag atttgatttc tattacgaaa
    11401 gaatcggaag atgatacaaa agaagcggta caagtctcgt acgaagaaat gacgaaggaa
    11461 gaaaaagaca cgttattgat gaaattagaa aaagaaatga aagatgcggc aaaagctttg
    11521 gattttgaaa cagccgcgaa tgtgcgagat atgattttag aattaaaagc ttcaaagtag
    11581 gaggacaaca tggctaacga taaaattacg attcatggtg cacgtgccca taacttgaaa
    11641 aatatagatg taacgattcc acgagataaa ttcgtggtcg ttacaggttt gtccggttct
    11701 ggaaaaagtt ccctagcatt tgatacgctg tacgctgaag ggcagcggag atacgtagag
    11761 agcctttctg cttatgctcg tcagttttta ggacaaatgg ataagccgga cgtagatagc
    11821 atcgacggat tgagtccggc gatttctatt gatcagaaaa caacaagtaa aaatcctcgg
    11881 tcgacagtag gtactgtgac ggaaatcaat gactatttac gcttgttgtt tgcacgtgta
    11941 ggacatccga tttgtcccaa cgatcatatc gagattacca gtcaatcagt agatcaaatg
    12001 gcagatcaag taatggcttt gcctgagcgc acaaagatcc aagtgttggc accgatcgtg
    12061 gtaaagaaaa aaggacaaca taaaaaaata ttcgaacgaa tccaaaaaga gggatacgtc
    12121 cgcgttcgag tcgatggtga gatctatgat ttaagtgaag tgcctgagct ggagaaaaac
    12181 aaaaaacatg atatcgcgat cgtcatcgac cggatcattg tgaaagaagg gattcgttct
    12241 cgcctatttg attctttaga ggcggccctg cgattagcag acggctatgc tctggttgac
    12301 gtgatcggtg aagaagaaat gttgtttagc gaacactatg cctgtcctta ttgcggattt
    12361 actgttggcg aactagaacc aagactgttc tcattcaatg cgccttttgg agcttgtcca
    12421 gactgtgatg gtttaggtgt caaattagaa gtcgatcaag atttagtgat tccagataga
    12481 acgaagacac ttagtcaagg tgctatcgtt ccatggaatc caatcagctc tcagtattat
    12541 cctcaaatgt tagcgcaggc ttgtgaaagt ttcggtatcg atttagatac accattcgaa
    12601 gaattaccgg aagagcatca ggagatcatc ttgaatggga cagatgatct tttccatttc
    12661 cattatgaaa atgattttgg tggcgttcgc gatgtagaaa cgactttcga aggggtattg
    12721 aagaatatcg agcgtcgtta tcatgatacg aacagtgatt tcacgcgtga gcaaatgcgt
    12781 ctttatatga cagaattaac ttgtcagaca tgtaaaggtt atcgattgaa tccccaagct
    12841 ctatctgttc aaatcaatgg aacgaatatc gggcaaacaa atgagttgtc tattcaaaaa
    12901 gcagtagatt tcttctcaaa cttaacgtta tctgaacaag agaaagtaat tgccaaaccg
    12961 attttaaaag aagtaaatga cagactttca ttcttggaaa atgtgggact agactatcta
    13021 actttgagtc gcgcttccgg aacattatct gggggagaag cgcagcgaat cagattggct
    13081 acacaaattg gatcgaatct ttctggagtt ttgtatattt tagatgaacc atcgatcgga
    13141 ttgcatcaac gcgacaacga tcgactgatt ggctcattaa agaaaatgcg tgatcttggc
    13201 aacaccctcg ttgtagtcga acatgatgaa gatacgatgt gggcagcaga ttatttgatt
    13261 gacgtcggac ctggggccgg agaacaaggc ggacaaatcg tggctgcagg cactcctgaa
    13321 gaagtagcta atgatgaaaa ttctttgaca gggaaatatc tttcagggaa aaaatcaatc
    13381 cctgtaccaa aagaacgccg taaaggtaat gggaaagcaa tcaagatcac tggtgcttca
    13441 gaaaacaatc tgaaaaatat tagtgttgaa tttccattag gagaatttgt agcagtcaca
    13501 ggtgtgtctg gttctggaaa gagtacattg gtcaatagta tcttaaagaa atcgttagcg
    13561 caaaaattaa ataagaattc tgctaagcca ggtaaattca agacaatttc cggctacgaa
    13621 agtatcgaaa agatcatcga tatcgatcaa agcccaatcg gccggacgcc gagaagtaat
    13681 ccagcgactt atacaagtgt atttgatgat atccgtgggt tatttgctca aacgaacgag
    13741 gcaaaaatgc ggggttataa gaaagggcgt tttagtttca acgtaaaagg cggtcgttgt
    13801 gaagcttgtc gcggggatgg aattattaag atcgaaatgc actttttgcc tgatgtctat
    13861 gttccttgtg aagtatgtca tggtaaacga tataattctg aaacattaga agtgcattac
    13921 aaaggaaaaa gcattgctga tattttggaa atgacagtag aggatgctgt agaattcttc
    13981 aagcacattc caaagattca tcgcaaactg caaacgattg ttgatgttgg cttaggttat
    14041 gtgacgatgg ggcaaccagc aacgacattg tccggtggtg aggcacaacg gatgaaactt
    14101 gccagtgaat tgcacaaaat ctctaatgga aagaatttct atatactaga tgaaccaacg
    14161 acaggacttc atagcgatga catcgcccgc ttgttgcatg tattacaaag attagtagat
    14221 gctggtaaca cagttttagt gattgaacac aatctagatg taatcaaaac agcagattat
    14281 atcattgatt taggaccaga aggtggagaa ggtggaggaa cgatccttgc gactggaaca
    14341 ccagaagaaa tcattaacgt aaaagaaagt tatacaggtc actatttgaa aaaaataatg
    14401 gtataaagag gatagatagc tgagatagtt aaaaaaacat aaaaaaatga atttttgctt
    14461 gttttattaa tatcagtgtt ctagaatcat tacatggtag ttctttctac actgattggt
    14521 atagataaaa acttcctata agttcaatcc gttcaaaaaa gaattgagca atcggaggag
    14581 tttcctttga ttgctttttt ctttatggta tgatattcct tgtgtagttg gaaaagaaaa
    14641 acaagagatt atgagtaagt gagagataat gatgaacagt attgaaaatg aagaatttat
    14701 ccctatatta ttaggaagcg acatgaacgt ttatggtatg gcacgttctt ttaatgaagc
    14761 atacggcaaa atctgccaag catatgcttc ggatcagtta gcccctaccc gctacagtaa
    14821 aattgtcaat gtagaagtta ttccaggatt tgataaagac cctgtattta tcgagacgat
    14881 gcttcgtttg gcaaaagaaa gatattctga taagagtaaa aaatatcttt tgattgcttg
    14941 tggtgatgga tatgcagaat tgatctccca acataaacaa gagctgtcag aatattttat
    15001 ctgtccatat attgattatt ctttatttga aaggctgatc aataaagtaa gcttttatga
    15061 agtttgtgaa gaatatgatc ttccgtatcc taaaacattg atcgtcagag aagaaatgtt
    15121 agtaaatgga catttggaac aggaattgcc ttttgaattc ccagttgctt tgaaacctgc
    15181 aaacagtgtg gagtatcttt ctgtccaatt tgaaggaaga aaaaaagctt ttattttaga
    15241 gactagagaa gagttcgatt taattttagg ccggatatac gaagccggtt ataaaagtga
    15301 aatgattgta caagatttta tcccgggtga tgatagtaat atgcgtgtgc taaatgcgta
    15361 tgtagatgaa gatcatcaag ttcggatgat gtgccttggt catccactat tagaagatcc
    15421 tacaccagca tcgattggta attacgttgt gatcatgcca gattataacg aaaaaatcta
    15481 tcaaaccatt aaggcatttt tggaaaaaat cgaatataca ggctttgcca atttcgatat
    15541 gaagtatgat cctagagatg gagaatataa attatttgaa atcaatttga gacaaggtcg
    15601 tagcagtttc tttgtgacat tgaacggctt gaatctggct cgttttgtca cagaagatcg
    15661 agtgttcaac aaaccctttg ttgaaacgac ctatggaacg aatcaatcag ataaagcaag
    15721 attatggatg ggtgtgccca aaaaaatctt tttagaatat gctcgggaaa atgaagacaa
    15781 aaaactagct gagcaaatga tcaaagaaaa tcgttacggt actactgtat tttatgaaaa
    15841 agaccgatca atcaagcgct ggttgttgat gaaatatatg ttccataact atattccaag
    15901 attcaaaaag tattttcatg tgaaagaagg ctagttcatg gagaattttt tcagtatttt
    15961 aggcggaatg ggcacgatgg cgacagaaag ttttgttcgc ttgatcaacc accgaacgaa
    16021 agctacaaaa gatcaagaat atttgaatta tgtcttattc aatcatgcaa cagttcctga
    16081 tcgtacagct tatattttag atcgatcaga agaaaatcca atgccgtttc tgctggatga
    16141 tattgagaaa caaaatttat tgcgaccaaa cttcattgtg ttgacttgta acaccgcaca
    16201 ctactttttt gaagagttac aagcggcaac ggatattcct atcttgcata tgccaagaga
    16261 agcagcaaat gaacttgtcc gtcagcatac gacagggaga gtagcgattc taggaacaga
    16321 aggaagtatg aaagctggaa tctatgaacg cgaagtcaaa aatcttggtt tcgaaacagt
    16381 gattcctgat actgcgcttc aagaaaaaat caattacctg atctatcatg agatcaagga
    16441 atcggattat ttgaatcaag agctctatta cgaaatctta gaggaagcgg tagagcgcct
    16501 aaactgtgaa aaagtcatcc taggttgcac agaattatct ttgatgcatg aatttgctga
    16561 agataatcat tacccagtga tcgatgctca atctatttta gcggatcgaa cgatcgaacg
    16621 tgcattagct gaaagaagcg aggcattgga tacagcatcg gaaaagtaaa aaaattggat
    16681 ttggggcaaa tatcctaaaa gatatttggt ccaaatcttt ttgtaaaaga aaaagaaaac
    16741 tggtaatgat acgcccggga tgatataatt ttattatgca caatgtgaga ggggttcgta
    16801 aatatgacag ataatttgca attagtcatc ataacaggta tgagtggtgc agggaaaaca
    16861 gtagctatcc aaagttttga agatatgggc tatttttgta tcgataatat gccgcctcga
    16921 ttgattccaa aattctggga attgatcaaa gaatcaggta aagtcacaaa aatggcttta
    16981 ggagtggatt tgcgttctcg ttccttcttt gaagaaatcc aaaacatgct gatcgaaatc
    17041 gaaaatacga acttcatcga cacttctatc ttatttttag atgcttcaga cgaagaacta
    17101 gtggctcgct acaaagaaac aagacgagca catccaatgg cgatggacgg tttgatcact
    17161 gaagggatac gtaaagaacg ggcgatacta gacgacttga aagcccaagc ttccgtgatc
    17221 attgatacga caacattgac accacgacaa ttacgtgaaa aaatcaatga gtcattcaaa
    17281 tcaaagggag accaaggatt tcggatcgaa tttgtatcat ttggttttaa atacgggttg
    17341 ccgatcgatt cggatattgt gatggatgtg cgttttttgc ccaaccctca ttatatcccg
    17401 gaactaagac cattgaccgg aaaagatcag ccagtctatg attatgtgat gtcctttgat
    17461 gaaacgcaat cattctacca taaatttttg gatcttctgg aaactgtatt gcctggatac
    17521 attaaagaag gaaaaagcag cttgacagtt gcaatcggct gtacaggcgg tcaacaccgt
    17581 tctgtggcat tgactgaacg tttggcaaat gctttaggga aaaactataa agtcaatgtg
    17641 acacatcggg acaaggataa aaggaaagag acggtgaacc ggtcgtgaaa atgaaaacct
    17701 accggataag aaaaccaaag atcgtagtgg tcggcggtgg cactggtctg ccagttatcc
    17761 tgaaaagttt acgaaatcaa ggagcagata tcacagcagt agtgactgtt gcagatgatg
    17821 gtggaagcag cggtgcaatc agagaatcga tcgctatggc tcctcctggt gacttgagaa
    17881 atgtcttagt ggcgttatcg gatatgccac aattctatga agatattttc caataccgtt
    17941 tcaaaaagga agatcagttt ttagccaatc atacgatcgg taatctgatc attgccgcag
    18001 tttccgagat gcggggaagc acttatgagg cgattcaatt attagcaaaa atgatgcatg
    18061 tagatggaca tgtttatcct tcttcagaaa ctcctttgac cttgcatgct gtttttaaag
    18121 acggaacgac tgcagtagga gaatctaaaa tcgcgatcaa ccgtaaaacc attgaccgtg
    18181 tgtatgtctg caacacaaat gataaaagtg aagccaaagc ggctcgaaaa gtcgtttcag
    18241 caattatgga cgccgacatg gtcgttttgg gacccggaag tttattcacc agtatccttc
    18301 caaatttagt gataccagaa atcggcgaag caatgctcaa gacaactgct gaaaccgtct
    18361 atatctgtaa tatcatgacc caaaaagggg aaacggaaca tttcacagat gccgatcata
    18421 tacgtgtttt acacaagcat ttgaatcagc cttttatcga tacagtattg gtcaatacgg
    18481 aaaaagtgcc tgaagattat atggacccag agatctatga tgagtatcta gtacaagtcg
    18541 cacacgactt caacggattg agaaatgaag gatgtcgagt gatttccacc gactttttag
    18601 aattgaaaga tggtggtgtc ttccacgatg gagacaaagt agtagaagaa ttgttccgtt
    18661 tagttttcgg ttcaaaatat taagcaattt attgttggag aaaggaggag aataggatgt
    18721 catttgctgc agatgtgaag aaagaactaa ctggtttgga agttcatcga gaacatgcga
    18781 aagcggaatt agctgctttg ctgcgaatga acggctcttt aggtattgtg aaccagcagt
    18841 ttattttgaa cgtccaaaca gaaaatgctg caattgccag acgtatctat tctcttttga
    18901 aagatcatta tcaggtacga agtgagctac tcgttcgtaa aaaaatgaaa ttaaaaaaga
    18961 acaatgtcta tatcgtccgg ttgaagcaag gcacaaaaga tgtgttgatg gatcttgata
    19021 tcatggatgg tatgatgttc aatggacacg tttcggacga gattatggga aattcgcaaa
    19081 aaatgcgttc ttacttacgt ggtgctttta tggcctcagg ttcagtcaat aatccggaaa
    19141 cgagtcgtta tcatttggaa atattttcta tttatgaaca gcataaccaa gacatttgcg
    19201 atatgttaaa ttattacggt ctacatgctc gaacgcttga acggcgcaat ggctatattt
    19261 cgtatttaaa aggagcagaa aaaattgctg atttcttaac attgattggt gcaaccaact
    19321 caatgctccg atttgaagat gttcgaatcg tacgggatat gagaaattcg gtcaatcgtc
    19381 tagtcaattg tgagacagca aatctgaaca agacgattga tgcggcttct aaacaaatcg
    19441 aaaacatcga attgatcgaa gcaaaggtcg gtctacatgc ccttcctgaa aaacttcagg
    19501 aaatcgcaga acttcggctt caacatccag aggtcagctt gaaagaatta ggggaaatga
    19561 ttccctcagg tgcaatatca aaatcgggaa ttaatcaccg aattcgcaaa ataaatgaat
    19621 ttgcggaaaa actgcgtgaa gaagcagttt aatccaaaga aaaaactgat acatgaagca
    19681 ggagatgcga atgtatcagt tttttttaaa agctatactt gcttttcttc cgtcaaacta
    19741 taattccaac tttactggag taacataatg ttgaaaggct tctattgttt tttaatacaa
    19801 tcgtataaaa agcggggaga caactgaatg aagattttag ttttatacat aaacttttgc
    19861 ttaatataga agtcctgata tagataggat caagtattta tctataactg gagattaatt
    19921 aaaaactgga aggaactgct cgatcaacct tgagaactgt ttttcttact tctggtcaag
    19981 attctcgtgg ttggtggata aggatggttg ataagttcat tggattagct agtcgaaaac
    20041 aaccaggtgt aattaatgta gaagttttaa caaggggatg gagtgattta ttcagtgata
    20101 atcataagtt cataaatagt aattgggatg tatggttggt atacgttata cctgaacttg
    20161 aactatcaag atttggttta gaatttgaga atcgatgttt ataaagggag ggcaaaaaat
    20221 gtgctttttt acaactttta ctatcattat gattgcagta ctttttattt ttctagatat
    20281 agcaaagcga aatacagcat ttttattata tcgggtttta cttcgagcag gtctcataac
    20341 atttatatcg atcgttggat tttttctatt cacagttatt gtatttattt ggagaactac
    20401 agcaccacca ttgccagaga ttacatatgg agaatttccg tttagtcttg aatatgaaat
    20461 agatgaggaa agaattttga ttgaagatac ggtgattgca gaatttatag gaagttttag
    20521 agggaatgtg acaactcaac ctagacgaag ttggagtata aaacttttaa ataatagtgg
    20581 agagttgaaa gcatttcatt atgaattctt aataatagaa agtgaagatg taacaatcac
    20641 tttaagtagt ggctctgctg gatattttat gaatgatggt ggaagcaagc cacagctcac
    20701 agtccgtgat cgtattgcag gttttatgca tttttctcac tatgacttag aagaagctcg
    20761 taaaatactt gcagaatatg ggatcacatt aatcaattgg gaatatgcgc caccgataag
    20821 aaattttttc aatgattatt attagtctta taaaaaacag aatgtaaaat ttatgtgcgc
    20881 gagtatttag ttttccattt tttgtttgat agatatatag cattgttgaa gcatgggata
    20941 gtggtgccaa ttttatcaat gaggttggtc aggcagttaa cataattggt gatgctataa
    21001 atccatttaa ttggaattgg aggaattagg tgtggaaaca gtgagattat ggatattcat
    21061 gaaaaatttt cgttcggctt tgagatatgt tattctggaa tcaaaatcag gttattatct
    21121 gattgacaca gatcactata ctttttgggg aggctacctt tttccgattt ttaattggat
    21181 aatcccccat aaggttatga aaattaactt gcctgcagaa gaaataaata gattaatact
    21241 caacaaagat ttacaaagga aaagagagaa agaacattct aatgttgctt ggataggtcc
    21301 agcatttgca gtagtgactt cttcaattgt cggtcctatg ctagagagta tttatagtga
    21361 tttttctatt ggaatacgtt atttatttgt tactttaagt atagctgttc ttttgtgcat
    21421 aaagggttat gttagcaaga agaataaaga tattttaaca ctaatcggtg taaacaattt
    21481 atctagtact aaaattatac tgtttcctga atctataaaa gaaggatcaa ggttgttgat
    21541 aatttttata atgcttatac tgttttctgt tttatttggg gtgatgttta taga
//
LOCUS       DAPBCF010000045        21280 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.046, whole genome shotgun sequence.
ACCESSION   DAPBCF010000045 DAPBCF010000000
VERSION     DAPBCF010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.046"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            133..507
                     /locus_tag="RD508_002071"
     CDS             133..507
                     /locus_tag="RD508_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDT7736624.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(621..1250)
                     /locus_tag="RD508_002072"
     CDS             complement(621..1250)
                     /locus_tag="RD508_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDT7736625.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1384..1456)
                     /locus_tag="RD508_002073"
     tRNA            complement(1384..1456)
                     /locus_tag="RD508_002073"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1421..1423),aa:Thr,seq:ggt)
     gene            1670..1743
                     /locus_tag="RD508_002074"
     tRNA            1670..1743
                     /locus_tag="RD508_002074"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1704..1706,aa:Asn,seq:gtt)
     gene            complement(1881..2045)
                     /locus_tag="RD508_002075"
     CDS             complement(1881..2045)
                     /locus_tag="RD508_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736626.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2340..3668
                     /locus_tag="RD508_002076"
     CDS             2340..3668
                     /locus_tag="RD508_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HDT7736627.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3870..4703
                     /locus_tag="RD508_002077"
     CDS             3870..4703
                     /locus_tag="RD508_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HDT7736628.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4719..5456
                     /locus_tag="RD508_002078"
     CDS             4719..5456
                     /locus_tag="RD508_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HDT7736629.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5611..6579)
                     /locus_tag="RD508_002079"
     CDS             complement(5611..6579)
                     /locus_tag="RD508_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDT7736630.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6811..7644
                     /locus_tag="RD508_002080"
     CDS             6811..7644
                     /locus_tag="RD508_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HDT7736631.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7678..8517
                     /locus_tag="RD508_002081"
     CDS             7678..8517
                     /locus_tag="RD508_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7736632.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8543..9103
                     /locus_tag="RD508_002082"
     CDS             8543..9103
                     /locus_tag="RD508_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDT7736633.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9302..11023
                     /locus_tag="RD508_002083"
     CDS             9302..11023
                     /locus_tag="RD508_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HDT7736634.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11188..12330
                     /locus_tag="RD508_002084"
     CDS             11188..12330
                     /locus_tag="RD508_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDT7736635.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12346..13557
                     /gene="thiI"
                     /locus_tag="RD508_002085"
     CDS             12346..13557
                     /gene="thiI"
                     /locus_tag="RD508_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDT7736636.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14130..14777
                     /locus_tag="RD508_002086"
     CDS             14130..14777
                     /locus_tag="RD508_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDT7736637.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14906..15122
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15170..17815
                     /locus_tag="RD508_002087"
     CDS             15170..17815
                     /locus_tag="RD508_002087"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDT7736638.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18125..19438
                     /locus_tag="RD508_002088"
     CDS             18125..19438
                     /locus_tag="RD508_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDT7736639.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19428..20081
                     /locus_tag="RD508_002089"
     CDS             19428..20081
                     /locus_tag="RD508_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7736640.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20136..20828
                     /gene="radC"
                     /locus_tag="RD508_002090"
     CDS             20136..20828
                     /gene="radC"
                     /locus_tag="RD508_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDT7736641.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20978..21178
                     /locus_tag="RD508_002091"
     CDS             20978..21178
                     /locus_tag="RD508_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7736642.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         7184 a         3550 c         4446 g         6100 t
ORIGIN      
        1 gtctacactc tgagatgtaa gaaatatcat aagatatttc ttacatcttt ttgttttgag
       61 caggacttta gataatttta ttaatatatg ctagcatgct tttgtaagaa aaagaaagag
      121 ggcgtattag ttatgtatct taaaattacg gaacaagcac aagaaagatt acaaaaatat
      181 attgatgaag gcgcaacagt tatattggat ttagatgatg gcgttgggga atattctaaa
      241 atgggtgttt gctctttaga tactagtttt cgtttacttc ttcttgataa agaacagaga
      301 aaaaatgatt ataaactcca attagatagt gatattgggg atgtttatat aaaagattat
      361 tcaaaaatgt acatggatga acatatgacc ctttctttag atccacgtct aggtgtattt
      421 actcttgaaa gcccaagtgg ttctttagac agtcatgttc aattagtaga tctacgacca
      481 gaaaaattct ctggaataaa acaataactt tctctctatt gtccataaaa ctagtctcaa
      541 tcaagctgta ttgaaaaaac aagacaacat tcttaccatg gtaaataaaa agacgacaca
      601 ttttgtcgtc tttttttaaa ttaactattt tcgataaaag atcgcatagc ttgtgccatt
      661 atttctggct tttctctatt caattcatgt tttccgtttt taataaagag tagccggcca
      721 ttcgttgaaa gtttatataa acgttttgct gctggtttat tcgcatgatc tttggtaccg
      781 cataaaatca atttaggaag tcgtgatgta cgaagctgtt ttttgcagtc taatgtttca
      841 agtgaacgaa gtagggtaag ggtttgtttt ttagatagac ctaatttttc aaatatctta
      901 gaaggtacgc agtaaaaata aatattctgg aaagtaagca ataagcgatt aggagactca
      961 aattgtggag cgactaaaac aacctttttt aaatatggag aaggagttgc aagatagttt
     1021 aaagcaataa cagcgcctaa agataatcca cataaaataa aaggttcctt tatctgattc
     1081 aattgtactt cgatgtattt ggttaagtcg tctaaagtag cagtgtctgt gctgtttaaa
     1141 tgattgaaca atgaaagact tttgcaagaa taactattgg gtagataaga gattacatct
     1201 ttccatgatt gttcgtcttg gcctagacca tgcaaaaaaa caattttcat attgctctcc
     1261 tttttatagt tatcatatag actttctttg tactattaaa atataaacat tcatttctta
     1321 cgtcataaaa taaaaaaaca gcgcagacac attgttaaac caacatgttg cactgtttaa
     1381 ggaagccact tgccgggctt gaaccggcga cctcttcctt accatggaag cgctctacca
     1441 gctgagctaa agcggcatta tcattaatac aaataatagg ataacgaata ttaatgtatt
     1501 tgtcaacaga attttttcga aaaaatgtgt ttctctaata ggaaaacaga ttttagaaaa
     1561 aataaaaata acaaaaaatg cgaacggttt ctttgataat ataataaaaa aattcaaaaa
     1621 aagtattgcg ttatttagaa gaaattgata ttatattcat gtacttgatt ccggcatagc
     1681 tcagttggta gtagcgcatg actgttaatc atgatgtcgt aggttcgagt cctactgccg
     1741 gagtaaataa agcttatgca aagaaaaaga aatccaatca cttgggtttc tttttctttt
     1801 attattatga tgaatcaagc tttctgtttt tgtcacgtat gttgtaatct ttacgaaaga
     1861 gtagagttgg ctactcataa tcaaccatac ttcccatcat cgctaaatac gaaataaatc
     1921 agcattccta caccaatcaa agcacaagct gcaccaagaa aagggatgac attcccaaag
     1981 ttatctgtat tcataagtat gccaccaccc acaaacaaaa agccgccagc aatcaggttt
     2041 ttcattttat tcatctcctt tcttacgtta tagtatttcc ttctttcaat gagtattttg
     2101 aaagctatct tattgtatga tgttcttcta ggcctcttct ttattataca ggccattttc
     2161 gttatctcat agaaatattc ctttttatct gaaaactatt gtataccgta tgacattttt
     2221 cttcatgaag ttgtaagtat attctcattc aaatgaaaat ttcatcatag aagagattgt
     2281 atttctaaat tcttaagagt aaaatacgaa gtataacttg gatttggaag gatgattgga
     2341 tgaaagctat tacgcctgat atgacaacaa aatttaacaa acagtttcaa gcaaatatca
     2401 aacagcaggc attgcagcgg gcagttgtga agaacggaat tactgcttct gctgaaaatg
     2461 tttcagcaca tgtggagaat acaccggtat tttctataga tttggctacg gggaaagtgg
     2521 ctaatcaaat gcaatcgggg cgttgctgga tgtttgctgc actgaacaca ttccgtcata
     2581 agatgctgaa tcaattccat ttaaaagagt ttgaattatc acaaaattac acttttttct
     2641 gggataaata tgaaaaggca aattatttct atgaaaacat cattgcaaca ggaaaagagg
     2701 caatcgatag ccggaaagta gctttcttac tcgctactcc tcaacaagat ggcggccaat
     2761 gggatatgat cgtttcatta ttccaaaaat atggcgttgt gcctaaatcg gtgatgccgg
     2821 aaagtgcgaa tagttcaaat tctcgagatt tgaataacta cttgaacaaa ttactgcgta
     2881 aagatgcagt agtgttacgg aaaatggttg ctcaaggaga aacattagac gctattgaag
     2941 aaaagaaaga agaaatgcta gaaagcattt ataacttctt agctatctca ttaggaacac
     3001 ctccaaaaga attcgatttt gagtaccgcg atgaagaaaa gaactatcat cttgaccgag
     3061 gactgacacc acaaattttt tatgataaat acatcggtgt aaaattagat gattatgtta
     3121 gcgtgatcaa tgcaccaaca aaagacaaac cattcaatcg ttcttataca gtagagatgc
     3181 taggaaatgt cgttggcggg aaagaagtca aatatctgaa tgttgatatg gaaactttca
     3241 aaaaattagc gattgctcag cttgaagaag gagaatctgt ttggtttggt tgtgatgtag
     3301 gtcaatcttc tactagaact agtggcatca tggccttaga tgcttattca atggatgatc
     3361 tatttgatac ggattttaca atgactaaag ctgaacgttt agattttgga gaaagtctga
     3421 tgacccatgc gatggtattg accggtgttg acttagtaga cgggcaatca acaaaatgga
     3481 aagtcgaaaa tagctggggc gaaaaagttg gaaagaatgg cttctttgtt atgagtgatg
     3541 cctggatgga cgaatatacg taccaaatcg ttgtaagaaa agatttattg acgaaagagc
     3601 aattaaatgc gttcaatgaa gaaccaattg ttctatctcc gtgggatcca atgggtgctt
     3661 tagcatagac gagtatttca atgaagagta tgtagtaaag ataaaaagag ctggcttaag
     3721 ccagctcttt ttatctttaa agtccattcc ctgtttttta tggtccctgt gctataattc
     3781 taaataaagg ataaggattg gaaataatcc ttttatcatt aaaaatatga tgacgaagta
     3841 gaataaaatt gggagtaggg gggaaagtca tggatatcca aactgtttta tctgatctga
     3901 aattaaatgg taaagtgatt ccagttgttg gtggagatgt taatcagacc tatcgtataa
     3961 aaaccgaaca tcgtgcttat tttttaaaaa tccatccgaa tgtaaaaaaa ggattttttg
     4021 aagcagaagt agacggatta aaagaactgt cagcattcgt acgtgtaccg gatacgtata
     4081 tgctaggtga aacaagtgaa ggcgcttatt tgttaatgga atggatcgag ccgggaaaag
     4141 gggatcaacg agatcttgct gcagctttag ctaatctcca tcagcaaaca gcgccacaat
     4201 ttggttttcg taaagataac tatttgggta cacttgttca gaaaaattct tttgaagaag
     4261 attggtggac ttttttcttt aaagatcggc ttgaatccca gatttctttg gcagaagaaa
     4321 cgaatcgatg gaatgtacag cgtcaagaaa agtatctgcg atttaaagaa cgtgtattga
     4381 aatcggttga accaaaaaag atcactccac gcctcttgca cggagacctg tggagtggta
     4441 atgtgttctt tgaccagcaa gggcatccag tttttgtcga cccagctgtt tcttatggga
     4501 atcgggaaca agatattgca atgagccagt tattcggtgg tttccgaccg gaatttttag
     4561 atgcttatca aactatattt ccattagaaa agggatggaa agaccgactg ccgatttacc
     4621 agttatatta tcttttggca catttgaata tgtttggaga aagttacggt tcccaagtag
     4681 atcaattact agaaaatttt taagaggagg gcgtgttttt ggcaaaaaaa tataccaaaa
     4741 agcatgaagt ttcatattat gagtgtgaca tcaaccaaac gatgacattt ccttcgatgt
     4801 taggagtagt tatcaaaacg tctgaagatc aaagcgacca gttgggaaga ggcagtgaat
     4861 tcgtcaatag ctttggactt acttgggtca tcacgaatta ttccatggag attaatcgtc
     4921 tccctagagt cggtgaagta atctcagtaa cgactcaagc catggagtac aataagtttt
     4981 tctgttatcg gaacttctgg atccatgatg aagatgggaa agaattagtc aaaatagaat
     5041 ctgttttcgt attgatggat tttgtgaatc gaaaaatgag cagtgttaat gaagagatca
     5101 ttgctccttt tgagagtgag aagatcaaga aaatcaagcg tcaggaaaaa attgaaaaga
     5161 ttgattcggg cttcatgttg ccatatcgtg ttcgttttta tgatatcgat agtaatcagc
     5221 atgttaataa tgcgatgtat tttaattgga tcattgacgt attaggatat gactttttga
     5281 ctacgcatgt tccagaaaaa gtaattattc gatttgataa agaagtagag tacgggaatg
     5341 agatcgaaag ccattttgaa caaatcccta tcgaaaatgg tgtcaaaaca aaacatgaaa
     5401 tccgaatgca agaacagctg tattgtgaag caaatattat atggaaaaat aaataaaaaa
     5461 gaggttgtga cagaaggggg caacttcaag aaataagaag aaatttacga aaattgtttc
     5521 tcaaattttt gtaaattttc gacttagttt tcgaagaagc tatttttgtc acagcctctc
     5581 tttttaagtt tagctattag ataatgatgt ttagttttgg ataaacgaaa tcaattcttc
     5641 acccgacaaa ccatagttta cagcaatcaa tagttttaaa cgtgcttttt gactattaat
     5701 actgttacag aaaataatcc ccattttttc tagttctttt cccccgcctt cataatcata
     5761 aacaggctct gcgattccat tgaaacaacg agaaacaagt actacaggga ttttttggac
     5821 aagaagcttt tccaaagcag ctaaggcttg tggagggaga ttccccgcac ctaaagcttc
     5881 gattaccaaa ccgtctactt tcgtatgggc gatggcttcc aataagtccc cttgcatccc
     5941 agcatatgct ttaacgatcg ggatagtccc atctacagcg gaaatgtcca gtcgctttgt
     6001 ttctaaaagt tcctgcaaga ataaaattcg attcttagtt actaagccga tgggacccaa
     6061 tgtaggtgtt cggaaagtag caacatttgt ggtatgggtc tttgtcacgt agcgtgcaga
     6121 atggatctca tcgttcatga ccaccaaaac ccccttatct agcgcttctt cacaacttgc
     6181 gacacgaatc gcactttcaa aattataaag gccgtcactt ccaagttcat tacttgaacg
     6241 cattgcccca gtcaaaacaa ttggtaattt gttgccaatc gttgtatcaa gaaaaaaagc
     6301 agtttcttct aatgtatctg taccgtgtgt gatcaccact ccggatatac ctgatgcata
     6361 agcggacaag atacgttctt ttaataccaa catgtgagaa ggcatgatgt gtggtgaggg
     6421 aagattgaag atatcttcaa ctaataattc tacatgcttg gggattgtga tttctgcatc
     6481 taataatggg tttgccacat caggactaac accgcccgtg agcatgtttt ctttcatggc
     6541 gatcgttccg ccggtgtgta gtacaagtat ttttttcatt ttacagactt ccttacgaat
     6601 aattttgcat agccgttaaa tcttattgta tactatataa aagagttttg ctatcagtga
     6661 agaataacga atagcctaac ttatcataaa aaagctgacc ttattaaaat ggaaaagact
     6721 caaccttgac ctcctaatac aatggagtat ctggttgagt ttcttttaca agaaagcagc
     6781 caaggaaatc aatcacgaag gtggccggaa atgatcagaa tcggattaac atcgtttaaa
     6841 gaacatgaca aattaactgg taaaaagaat aacactcttt atgaatatgc agggtttcta
     6901 cccttagtgg aattagatac tgcctattat ggaattcccc gaaagtcctc agttgagaat
     6961 tggataagtg aagtacctga atcatttcgc tttgtagtca aagtctatca aggaatcagc
     7021 ggtcaaggag actggaagcc ttattatcag accgaagaag agatgattgc gcatttttta
     7081 gatgttatgt cgccaatggt agatgctgga aagatgtttt gctttttagt ccaattcccc
     7141 tcatcattca aatgtacgaa agaaaatgtc cagtacttgc gcaaacttag aaagtggttt
     7201 gagggttatc ctgtttctat agaattgcgg gattattctt ggtacagcga tgaatttctt
     7261 gaacgtacaa gaaactttat gtctagagcc gctttttctt tagccatcat cgatgagcca
     7321 cagttgctga atacaacgat tccttttgat ccatttgtca ccaatccgaa ctttgctctt
     7381 tttcgattcc atggtaggaa tgcgcaagga tggcaagcaa atgataaaga gtggcgtaaa
     7441 aaaagaacgt tatatcgtta ttcagaaaaa gaactgcaag aactagcaca tgaagtcaaa
     7501 gtagttgatt ctaagacaaa agaggtaggt gtgattttta ataataattc tggtggtgat
     7561 gcggctgaaa atgcattagc actgcaaaaa atattaaata tcaagccaga tggactcaat
     7621 ccaacccaaa tggatctgtt ttaagggctt attttattca agaaaggggc gaagtctatg
     7681 atcaaagcta ttttttttga tattgacgga acattggtca ccaatcgttc aaaagcgttg
     7741 gaatcaacaa aacaagcaat tgaatatgct cggaaaaacg gcattttatg cggtgtagca
     7801 acggggcgca gcccagtaaa gatcaaagaa atcattgatg aattggaatt agatatgtat
     7861 gtcgtgtata atggtcaact ggtttttact gcagatcgca cgattatcga ccaccctttt
     7921 gaacaaaaag tattggaaca tattgttgaa tttgcagatg agaaccatcg acaaatcgtt
     7981 tttggtgcga gaaatcggtt agatggatca acgacgatgc tattaggaca atcgattttt
     8041 atcaagcgac tagtcagctt tttaccgcgt aaattcccgg tacgtctgat gaaaaaaatc
     8101 ctccaggttt ttagccctca ccgacaaaag gatcgttatg aaacgttaga gatattaaaa
     8161 gaaccaattt atcaatgtat attgctcagt ccggagtcag aacagaaaaa gttagaacat
     8221 cgctttcccg agtgtacgtt tcagcgttca aatacgtata ctgtagatat catcccaaaa
     8281 ggtggttcaa aattactagg catccaagct ttcgcaaatg ctgtcgaaat tgaaatggaa
     8341 gaaattatgg cattcggcga tcattacaat gatatcgaga tgctgaaagg tgtaggaatt
     8401 ggagtggcca tggggaatgc tcagatcgaa gtaaaacatg ctgcagactt tgtgactcaa
     8461 tcaaatgaag aagatgggat atacgaagga ctgaaacact tcggtctgat ttattagtca
     8521 atgaaagaag gaaaaaatca gtatggaagc agagacacct tttcaaaaag tagaaacatt
     8581 ccacaaaact tttgatccaa gaagaccaga gatacccacg gcttttacag aaaatgaagc
     8641 tcatacacgt gctgcgttca aaatagaaga acttgttgaa tttgttgcag ctacttcacc
     8701 taataaagaa caactgcatg aagctgttat gctgctgcac gaagcattag ataaagcaga
     8761 agaaaaaata cttggtaaaa cacagtgggg aagtgatccg ctggttgaac aagtagatgc
     8821 actgacagat atcctttact ttacttatgg ttctttttca ttactaggaa tagtgcctga
     8881 tcgaatattc gaaatcgtcc atcaggcaaa tatggggaaa ttatttccag atggaaaacc
     8941 tcattatgac cctgtaacaa ataaagtgtt gaaacctgaa aactggcaga tggaatatgc
     9001 tccagaacct aaaatcgcgg cagaaatcca acgtcagatt caagaagcga ttgctaagaa
     9061 gaaatccgct gatataggca tgtgcacaaa tgaaaaagag tgatcagagt ttcactattt
     9121 ttgttatctt tatacgatgg aaaaacaaaa gattttcgtt taagttagtg aatgcatgaa
     9181 aatagtatgc tataatctag aatagatgtc ttttgcacga gagacgtatt atttggattt
     9241 atgccaagca gaacgccatc tgttgcataa aagatgcata ctgaaaacgg aggaaccata
     9301 aatgggaaat aatgttatca tcggaatcgt cattgcaatc attatagtcg ccattgtcgt
     9361 ctttttggtt agttacttga tgaagaaaaa aaaccaagat cgattggatg ccttagaaaa
     9421 acgcaaggaa gaattatttg acttgccagt gattgaagaa gtcgatgatg ttaaaaaaat
     9481 gcatctggtt gggcaaagcc aaaatacctt tcgtgaatgg agtcaaaaat ggaatgacat
     9541 atctacttcc tcgttcgctg aactagaaag tcaaattttc gaagtggaaa acctcaatga
     9601 aagttttcgg ttcttaaaag gaaaaaaagc agttgttgaa gcagaagcta caatggacca
     9661 aatggagaaa caagtgacgg aaatccgtga aggtctaaag gaattgcggg aaacggaaga
     9721 acgcaactca ctagctgttc agcaggcact tgacgtctat gaagaactga aagaaaaagt
     9781 cagagaagac gagcatgaat acggaccagc tctttttgaa ttgcaaaaac agatcaaagt
     9841 gatcgaaaaa gaatttacgc agtttgtgac tttaaacact tctggagacc ctgttgaagc
     9901 ccgcgaggtt ttggataaag cagaaaaaca tacgtatgaa gtggaagctc tgatgaaaaa
     9961 aattccaccg ctgtatgagg agctccatac cactttccct gaacaacttg aagaaatcag
    10021 tgatacttac gagaaattga tggaagaaca atatgtattc ccagaagaag atcttgctga
    10081 agatatcgca aaagtaagtc gaagaattga aaattcatta gccaatcttg aaaaaacaga
    10141 agttgaaacg gtcgaatttg aaaaccgtga aacagctgat ttgattgatt cgttatatga
    10201 tatcttagaa cgggaaatgg aagctcagag atatgtaaaa actaaccaat caacgattgc
    10261 agagtatatc aaacatacaa caaagaataa ccgtcaatta ttgattgagc tggatcacac
    10321 atctcaaagc tatacattga accacaatga aattggccgt gtacgaggtt tccaaaccga
    10381 agtggaagaa atggaacgtc aaaatgaaca gatgattcca cagatccgtc aacacgaaat
    10441 tccttattca gaagtgcgca cgttctataa aacagtcttc aaagtcttag aagatatcga
    10501 aaagcaacaa gtagagatcg acgactcatt acatgaattg agaaaaggcg aaaaagaagc
    10561 gcaagaaaag atcgatacat tcgaattcaa attgcgcagt ttgaaacgtt ttgtagaaaa
    10621 acaacgtttg cctggcttgc cgaatgatta cctagaattc ttttttgttg ctactgaccg
    10681 tattgaagaa ctaagtgttg tcttgaataa aattcgagta aacatggaag aggtcaatcg
    10741 tttagttgct ctatgtgaag aagatctaga attattagat aagaagacac atgatttagt
    10801 agatgcagca gcattaacgg agcaaatgct ccaatatgca aatcgttatc gtcatacaca
    10861 cgaagaagtg agagaagcaa ttgataaaag ctactattta ttcaataaag aatatcacta
    10921 tcaagaagca ttagacgaaa tcggtacagc attagagcga gtagaacctg gtgctttcaa
    10981 acgcatcgaa gatttttatt ttaatcatcc agacttagta taaagcaaaa aagttagtaa
    11041 accagcaaga gcaagacgga ttattgtctt gttcttgtct ttttttgtat atttgaaaat
    11101 tgaaacaagt gaaaatttca cctgctcttg aaagcacctt ggacaaccgt tataatagaa
    11161 aagaatttca aaaaagaggg gtttcttatg atatattttg ataacagtgc aacaacccca
    11221 atctttccgc aaagcttaga tgcatatgta aaaaccagtc agcggattat tgggaatcca
    11281 tcaagcttgc atgatttagg caatcaagct aaccggttgt tgcagcaagc aagaaagcag
    11341 atcgctgatt tgatccatgt agaaccagaa gaaatctatt ttacttcagg cggaacagaa
    11401 ggagataact gggtattaaa aggaacgatg atcgaaaaaa gagaatatgg gaatcatatg
    11461 atcatttcag gagtcgaaca tccggccgtc agcgagacag cagaacaatt aaaagaatta
    11521 ggaatcgaag taagtatcgc cccagtggat aaacgcggat ttgtacgtgt cgacgaattg
    11581 aaagaattaa taagaaaaga gacagtatta gtctctgtta tggctgtgaa taatgaagta
    11641 ggatcgattc agcccatcca ggaaatcagt gatcttttgg atgattttcc taaaattcat
    11701 ttccatgtag atgctgttca ggcgattgga aaagtaccat tctcgcaatg gttgacagaa
    11761 agagttgatt ttgcaacatt ttcagctcat aaattccatg gcccacgggg aactggtttc
    11821 atttattgga aaaagggtcg tcgtttagca ccattactga caggtggagg gcaagaaaga
    11881 aatcagcgaa gtgggacaga aaatgttcca ggtattgtgg ctatggttaa agctttacgt
    11941 ttatcattag agataaagga acaaaaacct gagcagacac aacgcttaaa agtagctcta
    12001 atcaatgcgt tgaagacgta tgagaaagtg acgatttttt cagaaggaac tgactatgca
    12061 ccgcatattt tatgttttgc tctaaaagga attcgcggcg aagttctcgt ccatgcctta
    12121 gaagaaaaac aaatatttgt ttctactact agtgcctgct cctcacgtaa acatatggca
    12181 agcagtacat tgcacgcaat gcatgtacca aatgatctgg ctacatctgc tgttcgaatc
    12241 agcttagatg aaaacaattc gcttgcagaa gtcgagcaat ttatgattat tttcaagcag
    12301 ctttataaga aattttctgc aatcaattaa aagaggagtg ttcttgtgaa atacagtgaa
    12361 attatggtcc gttatgggga actttcgaca aaaggaaaga atcgaaaaag ctttatcatg
    12421 caactagcac aaaatgtcag acaagctttg aaagactttc cagaaatcaa aatccatgct
    12481 gatcgggacc ggatgcatct tttattgaat ggcgcagacg ggcagctagt tattccaaaa
    12541 ctagcaaaaa tatttgggat ccaaaatttc tctccaagta ttcgtgtaga aaaagatgtc
    12601 gaagttttga aacaagctgt tcaagacatc atgaaagaaa tttatactgg gaaagaaaca
    12661 tttaaaatta tcgctaaaag aagcgatcac caatttgaat tgacaagtaa tgaattgaat
    12721 caaacattag gtaatgctgt ttttgatatt ttcccgcata tccaagttca aatgcgtcaa
    12781 ccagatattc cattacgtgt agagattcgg cgtgatggcg cttatctatc gtatgaaacg
    12841 atcaagggag ctggaggatt gcccgtagga acaagcggaa aaggaatgct tatgctttct
    12901 ggggggattg attctcctgt agcagggtac tttgccatga agcggggagt ggaaattgaa
    12961 gctgttcatt ttgctagtcc gccgtataca agtgaacaag cactgcaaaa agcaaaagat
    13021 ctaacagcca aactagcacc ttatgtggga acgatccatt ttatcgaagt gccatttacc
    13081 gagattcaag aagaaatcaa aaagtcagtg ccacaaggat attggatgac aattactcgt
    13141 cgaatgatgt tgcgtttgac cgatgaaatt cgccgtattc gtcatggttt agtcattttg
    13201 aatggtgaat cattaggtca agtggcttca caaactttgc aaagtatggt ggctatcaat
    13261 gaagtaacga atacgccaat cattcggcct gtagcgacaa tggataaact tgaaatcatt
    13321 gaagtagcag aacagatcga tacatttaat ctttctatcc agccttttga agattgctgt
    13381 acgatttttg ctcctccaca gccaaaaaca cgccctcaac tggaaaaggt ccatcaatat
    13441 gaagagcgtt tagcaataga tgaaatgatc caacgagcac tagctggctt gaagatggaa
    13501 gagatacaag cagaatcgtc taatgaaaaa actgaagaat tttcagaatt gctataagag
    13561 gttatgaaaa tagtgttttg accagagtat tagagaaaca aaacgaaaaa atagctccat
    13621 gtattttacc gtttttgaac taatgtcgaa gattagctga ttgaatacca tttatcaaga
    13681 agttatggaa aagccggttc ttttttacta actgaaaaat aaaattttat ttagagatca
    13741 agctacagtt gataaatgat ataaaaaaga gaatttccca tgaaatagcg aggttgtgac
    13801 agaagtgggc agcttcaaga aataagaagg aatttacgaa aattgctttt caaatttttg
    13861 tgaaatttcg gcttattttt cgaagaagtt acttctggaa caccgtgtat cagaggttgc
    13921 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagtt cctcatattt
    13981 tacgtttggt tgagcttatt accgcagatg caagcttttg aacaccgttt tatttgtctc
    14041 acaccctttt ccttcctact tgtaaccttg ctcccgtgtt agaaacatgt tacactaaat
    14101 atgtgaaatt attaacaagg agcgtcgtta tgcgagaaaa aacagataca ctgccaaaag
    14161 caactgcgaa aagattacct ttatatttac gctacttgaa gatgctggat gactcaggta
    14221 taagtagaat caaatcaaat gagttcagcg aaatcaccca aattccttct gcaacgatcc
    14281 gcagagactt ctcgcaatta ggcgagctag gcagaagcgg atatggctat gatgtccctt
    14341 ttcttatcga tgtattcaat aatatcctta atactaaaga agaaaaacga atcgcattag
    14401 taggatatgg aaatcttggc aaagcattga aacacaacaa ttttagaaga aatgaaaatc
    14461 taaatatcgt gtgcgtcttt gataatgatc cagcactgat caatcgagta attgatggag
    14521 aaatgatcta tccgattgat cgtttcgcgg agatagccaa agcaaaaaat gtgacagtag
    14581 caatctctac ggtaccaagt aaatattcac aatctgctat tgatgaaatt gtcaaaggaa
    14641 atgtaaccgc tatacttaat tttgcgcctg acagagtaac tgtcccagct tatgtcaatg
    14701 ttcaatacat tgatttgaca accgagttgc agacgcttat ttactttgat gagaattact
    14761 cagaagtttt ttcttaggaa aatttgagta ggcttattga tcttgcgaga actcgtcgta
    14821 attctttcaa aaatttttta gtactaaatg aagtggtttt ttcacgacca cttgttgact
    14881 aaaaaaaaaa accattgtag aatgaagcat aacgctgaac aagaggagta actggcacat
    14941 tcattcttag agagagaact atctgctgaa aggttctcaa tgacaaccag tgaaggtagc
    15001 ttgggagttt ctgtcttgaa tggagtagag atagacgagt cgtgatcgtt aactcacttg
    15061 agaggcaata atgattgatt attgcaattt aggtggtacc gcgtaaatca tacgtcctag
    15121 aatacgaaag tattttagga cgttttttag tttaaaggag gaaaacagca tgacggaaga
    15181 aaataaccta tcaacaaaat ataatccgca agaagttgaa gctggacgtt atcagcattg
    15241 gttagaacaa gatttgttta aaccgagcgg agataaaaaa gcaaaacctt attcaatcgt
    15301 aatcccgccc ccaaatgtta ctggaaaact tcatttaggg catgcttggg atacgacctt
    15361 gcaagatatg ctgattcgtc aaaagagaat gcaaggatat gatactttat ggctgcctgg
    15421 tatggaccat gcaggaatcg cgacacaagc aaaagtagaa gcgaagctta gagagcaagg
    15481 gatttctcgt tatgatctag gtcgtgaaaa gttcatcgat caagtgtggg aatggaaaga
    15541 agagtatgcg agccacatcc gcgaacagtg ggctaaaatg ggcttatctt tagattacag
    15601 tagggaacgt tttacattag atgatggatt atctgaagca gtacgtaaag tttttgttac
    15661 cttatacgaa aaaggtttga tttatcgtgg tgaatatatc atcaactggg atcctcaagc
    15721 acgaacagct ctatctgata tcgaagttat tcataaagat atcgaaggcg ccttttatca
    15781 tatgagctat gaactagcag atggatcagg cgtagtagaa attgcgacaa cccgtccaga
    15841 aacgatgttg ggagatacgg cgattgctgt tcatccagaa gacgagcgtt atcaagcgct
    15901 catcggcaaa aaagtgattc tacctttagt caataaacaa atcccaatca ttgcagatga
    15961 atatgtagat atggaattcg ggacaggtgt agtaaaaatc actccagcac atgatccaaa
    16021 cgactttgag gtaggtaatc gtcatgatct tccacgcgta aatgttatgg atgatgatgg
    16081 tacgatgaat gaactagcag gaaaatatgc tggaatggaa cgttttgctg ctcgtaaagc
    16141 aatcgtgcaa gatctgaaag aaatcggtcg attgattaaa atcgatacga tgatccacag
    16201 tgtgggtcat tccgagcgga caggtgtcgt tgttgaacct cggctgtcta ctcaatggtt
    16261 tgtaaaaatg gcgccgttag cgaaaaaagc cattgataac caagaaacag atcaagcagt
    16321 ggaattcttc cctccaagat tcaatcaaac gtttttacgt tggatggaaa atgtccatga
    16381 ttgggtaatc tcacgacaat tatggtgggg acatcaaatt cctgcatggt atcacaaaga
    16441 aacaggtgaa atgtatgtag ggatggaagc accagcggat agtgaaaact gggtacaaga
    16501 tcctgatgtt ttagacactt ggtttagttc agctttgtgg cctttctcaa caatgggctg
    16561 gccagatacg gaaagcgaag attataagcg atacttccct actagcactt tagtaaccgg
    16621 ttatgacatc attttcttct gggtaagcag aatgattttc caaagcttgg aatttactgg
    16681 cgaacgtcca tttgagaatg tcttgattca tggattgatt cgtgacgaac aagggcggaa
    16741 gatgagtaaa tcattaggta atggaatcga tccgatggaa gtaatcgaaa agtatggagc
    16801 agatgctctc cgctggttct tatcgaatgg ttctgcacca ggacaagatg tccgcttcag
    16861 ctatgaaaaa atggatgctt cttggaactt tatcaacaaa atctggaatg cttcacgttt
    16921 cgttatcatg aatatcgaag gaatgaccgt agaagagatc gatttatctg gagaaaaatc
    16981 agtggctgac cggtggatcc ttactcgttt gaatgaaacg atcgaacgag taactgagct
    17041 atttgatcgt tttgaatttg gtgaagcagg tcgacaactg tataacttta tctgggatga
    17101 tttttgtgac tggtacatcg aaatgagtaa agaagtactt tatggagatg atgctgtttc
    17161 aaaacaaacc acccgtagca tcttagtcca tacacttgat cagatcctac gtttattgca
    17221 tccaatcatg ccattcgtta cagaagaaat atgggaacat attcctcatc agggaaattc
    17281 tctagtagtg gcagaatatc ctgttgtacg tccagagttt gatgatgaaa cagcttctaa
    17341 agggatggaa gtattgaaag aattgattcg agccgttcga aatattcgtt cagaagtgaa
    17401 tacaccattg tctaaaccaa ttacgttgct aattaaaaca aacgatgcta aaatcgatca
    17461 atttttagtt gaaaatacaa gctatatcga acgcttctgt aatcccgaag agttgacgat
    17521 atcaagtgag atcactgcgc cagatctagc gatgtcagct gttctgacag gtgcagaaat
    17581 cttcttgccg ttagcaggat tgatcaatat tgaagaagaa atcaaacgat tagaaaaaga
    17641 actggaaaag tggacaagcg aagtaaaacg tgtccaagga aaactttcta atgaacgttt
    17701 tgtttctaac gcgccggaag aagtagtaga ggcagagcgt gcaaaagaaa aagattattt
    17761 agagaagcaa acggctgtca aagaacgaat cgaaagtttg cgtactattc aataagaata
    17821 gaaaaagaga gtgtgaaatc agctagctat tactaaaagc tagctgattg aacatcgtta
    17881 caggaaagag tttgagcctc actcttagct tcgattcata aggagatgtg acataaattt
    17941 tgtcgcatct cttttttagt ctactcttat tatgtaggag aaggagggag gtggatcatg
    18001 tatcaagagt caataaagta gttgataaaa tcgttcctct ctctgtttct tttctctttg
    18061 tcatactttt atttttctta tgtgttctat ttgttataat aaaagagaaa tgggggaatt
    18121 gttgatgacg attgaagaag caatagaatg gatccatagt cgattaccat ttggttcacg
    18181 tcctggcctt gaccgagtcg aagctttatt agaagtggta gggcatccag agagaaaagt
    18241 aaaaacgatc catatcgctg gaacaaacgg aaaaggttct actgtagctt atttgagaag
    18301 cctattagaa gaggctgggc tgacagtagg tacatttact tcaccttata tcgaaacgtt
    18361 caatgaacgg atcgcaatca atggcaaaag cattccagac aatgatttga tccagcttgt
    18421 aaaaaaatat cagccactga tcaaacaact tgatcaattt gaagcagtag ctggtattac
    18481 tgaattcgag acattaacag caatggcatt tgattatttt ttgatgaaga aagtggacgt
    18541 agcgattatc gaagttggct taggcggctt attggattct accaatgtag ctgtaccaat
    18601 gctgacggga ataacaacga ttggacttga tcataccgaa atacttggag atacaattga
    18661 agaaatcgct gcacaaaaag ctggaatcat caaacaaggc gttccagtag taacaggaaa
    18721 tattgcccca gaagctttta ctgtcatcca acaaacagct aaagcaaaaa atgcaccgct
    18781 ttatgtatac ggggaaaatt ataaaataaa ctatctgcat cctgatgaga tgtggggaga
    18841 agtatttgaa ttttttaatg aaataggaaa gatccctcaa ttaaccactc cgcttttagg
    18901 gcaacatcaa gctgaaaatg caggagtagc catcgaattg tattttgttt actgtcaatt
    18961 ggaaaagctg cctttccgag aaaaagatgt tttgaaggga ttgaagaaat ctcgatggcc
    19021 aggaagaatg gagcgtttga gtaacgagcc attagttgtt ttagatggtg cccataatac
    19081 gcatgcaatg aaccggcttg ttgagaattt gaaaaaagaa ttcaaaggat atcaaatcaa
    19141 cattttgttt tccgccttac gaactaaaaa tgttagagaa atgctagaac gattgcagca
    19201 agtaccaaat gtccatattt atttgacgac ctttgaacat ccaaaagcca tcgaattaag
    19261 tgaagtatca gatttagcaa gtgagagagt atcaatcgtt tcattgtggc aattcggatt
    19321 agcagatata ttggaaaaga tgacaaatga agacgtatta gttgtgaccg gttcacttta
    19381 tttcatttca gaagttcgcc atttattaat acaattagga ggagatcatg aagtataatg
    19441 cagtgatttt tgacatggat ggtttgctgt tcgacacaga gttagtgtat tacgaagcca
    19501 cacaagtagt agcagacaag atgggttttc cttatgataa agacctgtat ttaaaattct
    19561 taggtgtttc agatgaagaa gtatgggcga attatcatat gattttctcg gaatttggca
    19621 aaacaagtgt acaaagattc atagatgatt cataccagga aacgcttgaa cgtttttcgc
    19681 aaggagcggt acaaatgaag cccggtgtgt tggaactcct ctctttttta gaagaacatc
    19741 agattcccaa agttgtcgct tccagtaacc aacgagcagt cattgaactt ttattgaaga
    19801 agaacaatct gtttgaacga tttgagacga ttgtttctgc agaaaatgtt caacgagcaa
    19861 aaccagaccc agaaattttc ttgttagcta atcagaagct aggtacagcg aagaaagaaa
    19921 cattgatttt agaagattca caaaatggta ttttagcagc ttctgcggct gagatcccgg
    19981 tagtcatggt accagatctg cttccaccat cccaagaatt gatcaaaaaa acagctgggg
    20041 ttgtttcttc tttacatgaa atccctgcat tgttaaaata aaaatccatc tcttttcgta
    20101 tcttatttta gataagatag aaaggagatg tttttttggg aaaacgattg atcaaagaag
    20161 tacctactag ctctttacca agggaacgta tggaaattta tggcgcggaa gctttatcgg
    20221 atcaggagct tttggcaatc ttactgcgta ccggtcaaca cccttatagt gtgatgtcga
    20281 ttgctggaaa tctgttaaaa acgtttggag gactggcctc tttacgacag gctactttgc
    20341 atgagttaga agagattcga gggataggac gcgtgaaagc aatcgaaatc aaagccttga
    20401 tcgaattagg tcgacgaatt cagacggatc atgaaagagc ggctccaccg gttcgtacca
    20461 gctacgaatt ggcccagcaa ttgattctgg aaatgaaaga tcacaaacaa gaacatttgg
    20521 tttgtattta tttggacacg aagaatcaag tgatcttaaa aaaaacagtg ttcatcggtt
    20581 cgctgaatca gtcagtcgct catcctagag aaattttcca ttatgctgta cgttattgtg
    20641 cagcaaggat cgttttagcg cataatcatc cttctggtaa tgttattcca tcgcagcagg
    20701 atatgaattt taccaaaagg atacaaaagt gtggagaaat gatggggatc actgtactgg
    20761 accacttgat catcggacgc aaacgatatt ttagtttgag agaagaagga atgatggaag
    20821 agaagtaagt tgctttcttg caaaaaaaat gaagcaagtg tacaattata ttgtaatttt
    20881 gtttgggaat agaagttgaa acatctgttg cacctctatc gtacacgagc aatgttacaa
    20941 tttaaattag tgcttttggc acgaggagga tattattatg gaaaacggaa cagtaaaatg
    21001 gttcaacgct gaaaaaggat ttggatttat ctcacgtgaa gatggaagcg acgtattcgt
    21061 tcacttctca gctatccaag gtgacggatt caaaacatta gaagaaggtc aagcagtgac
    21121 tttcgacgtt gaagaatcag accgcggccc acaagctgca aacgttgtaa aagcttaatt
    21181 ttatctgtaa atcaaattga tggtagacat caatttttac gagagaacaa agcgagtaac
    21241 aaaaatacct gccacaagag acaatttctc ttgtggcagg
//
LOCUS       DAPBCF010000046        20449 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.047, whole genome shotgun sequence.
ACCESSION   DAPBCF010000046 DAPBCF010000000
VERSION     DAPBCF010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.047"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            140..460
                     /locus_tag="RD508_002092"
     CDS             140..460
                     /locus_tag="RD508_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736643.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            912..1112
                     /locus_tag="RD508_002093"
     CDS             912..1112
                     /locus_tag="RD508_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7736644.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1259..4048
                     /locus_tag="RD508_002094"
     CDS             1259..4048
                     /locus_tag="RD508_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDT7736645.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4095..4622
                     /locus_tag="RD508_002095"
     CDS             4095..4622
                     /locus_tag="RD508_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HDT7736646.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4643..5833
                     /locus_tag="RD508_002096"
     CDS             4643..5833
                     /locus_tag="RD508_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7736647.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5873..7171
                     /gene="asnS"
                     /locus_tag="RD508_002097"
     CDS             5873..7171
                     /gene="asnS"
                     /locus_tag="RD508_002097"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDT7736648.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            8224..8898
                     /locus_tag="RD508_002098"
     CDS             8224..8898
                     /locus_tag="RD508_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDT7736649.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            8895..9236
                     /locus_tag="RD508_002099"
     CDS             8895..9236
                     /locus_tag="RD508_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736650.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            9266..9625
                     /locus_tag="RD508_002100"
     CDS             9266..9625
                     /locus_tag="RD508_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HDT7736651.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            10149..12230
                     /gene="cadA"
                     /locus_tag="RD508_002101"
     CDS             10149..12230
                     /gene="cadA"
                     /locus_tag="RD508_002101"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDT7736652.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            12541..14007
                     /locus_tag="RD508_002102"
     CDS             12541..14007
                     /locus_tag="RD508_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7736653.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            14622..15161
                     /locus_tag="RD508_002103"
     CDS             14622..15161
                     /locus_tag="RD508_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HDT7736654.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            15235..15675
                     /locus_tag="RD508_002104"
     CDS             15235..15675
                     /locus_tag="RD508_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HDT7736655.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            15688..15897
                     /gene="copZ"
                     /locus_tag="RD508_002105"
     CDS             15688..15897
                     /gene="copZ"
                     /locus_tag="RD508_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HDT7736656.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            15897..18083
                     /locus_tag="RD508_002106"
     CDS             15897..18083
                     /locus_tag="RD508_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDT7736657.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            18103..20274
                     /gene="copB"
                     /locus_tag="RD508_002107"
     CDS             18103..20274
                     /gene="copB"
                     /locus_tag="RD508_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HDT7736658.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         6825 a         3553 c         4436 g         5635 t
ORIGIN      
        1 aaaaagaggt tgtgacgtgg tcacgacctc tttttgacga ttatgataca aaaaacatca
       61 tttatgaaca aaatgtgaat aacgggcgtt cttgagatat gattttaatt gggaaaaact
      121 tatcgataag gaggtcttta tgaaaaaaag actgttatgg tgtttgctgt ttctatccct
      181 aagtttaaca agtcagccag tttttgctga agaaacacag cggtctccta ttacaggcac
      241 acgtctgtac aaaaatgttt atgtacagac aacagatctt gattctgcga ttcctgaaac
      301 agaagaacgg tctttgcagc caagatttgg ttacttttgg tactgtccga cctgtgatta
      361 tgaaagttgc tggcatttct tacattctac agctgcagct tttgctttta ctcatactca
      421 gaaatatgat ggacatcatc ctgttattta tgaggtatag atatgagcaa aaaagaaaaa
      481 ctaatctcgt tgatcgtatt ggtttgcctt gttcttctgg taactgtcat aggctatcag
      541 aaataccatg agaacatcag acctactaaa gaatcttccc cagcctcgac cgttgaaaca
      601 gaaccgataa gtagtcagaa agaataattt ttttagttta aagaagaaca tcagagcaaa
      661 aaaacaccaa ctgaacaata tgtcgtttat tttaaaaaaa gttcggtttt tcactttatg
      721 taatcgctga gaaaactttt tttaataaaa aaagtcgaaa aactctagct tttttgtaaa
      781 cggtatgata tactatagga gtagtttttg ttcggtaatc tgtggtagct tgtttcaaat
      841 aaacatcttc cagatataca ccattcaagt aattgcaaaa tatgtgttga tacacaagga
      901 ggatttttat tatggaaaca ggtacagtaa aatggtttaa ctcagaaaaa ggatttggat
      961 tcatcactgc agaaaacgga aacgatgtat tcgttcattt ctcagctatc caaggcgacg
     1021 gattcaaaac tttagaagaa ggccaagcag taactttcga tgttgaagaa ggccaacgcg
     1081 gacctcaagc aacaaacgtt actaaagctt aattaaccta tactaaaaaa taaacgccca
     1141 gacatttgcg tgtctgggcg tttttgtcta ttttctttaa aaagcgatga gagtattttt
     1201 ctgcactttg tagtataatt tcaaaagaac attagaggca ggagaagagg aagatatttt
     1261 gaaaccaaga acttatgcag tcgttgatat cgaaacgact gggacgaatc caaaagaaga
     1321 tcggatcatc caatttggct gcgtcatgat tgaatcaggt cggatcactt cacgtttttc
     1381 gatcgatatt catccagggc ggaagatttc aaaacaaatc cagcatttaa cagggatcac
     1441 gaatcaacgc gtccaaaaag cgccttattt cgaagatgtc gcccaaacga tttacaatct
     1501 tttggcagac accatatttg tcgcgcataa tatttatttt gattataatt ttttgaacca
     1561 tgaactcatg cgatgcggac ttcctagttt gaagatacca ggcatcgata cagtagaact
     1621 tgcacaaatt ttcttgccga cggaaccaag ctttcgctta gctgatttgt cagaaagcct
     1681 tggatttatt catgagaatc ctcatcaggc agatagtgat gccgaagtga cgggtcaact
     1741 tcttttgctg atcgaagaac ggatgagaaa attgccaatc atcacgttag agcagattgc
     1801 gcgattaagt agacacacag gtatggatac gagtcgtttc atttatcatg tgattgaaga
     1861 aatgaaagaa aaaccagagc cacttgatcc ctcattagaa atcgtcgatg ggctagcttt
     1921 gcagaaaaaa gaagtggaac tattcacatc cgtccattat ggcgagcgga catatccaag
     1981 aaaaaaacaa gcaaaagaaa aaatgtttgg taaaacactg atgtatcgaa aagaacagaa
     2041 cagactgatg aatgcggtct acgaccattt cacaaaagat gaatcaaaag atttgatgat
     2101 cgaagcagct acaggaatgg gtaaaacaat cggttatctg ctgccattga gttatttggc
     2161 tacacctgaa aaacccgctg tcatcagtac cgtttcgcta gttttgcagc agcagatcat
     2221 agaaaaagac attccattgc tgaatcaatt gctagatcag cccatacaac ctgtaattat
     2281 caaaagctat cgccactata ttgatttaca gcgttttaaa ggcacacttg tggaaccgcc
     2341 agaacaaaaa caatatgctt tgtatcaaat ggcggtctta gtttggctga cgcaaacgaa
     2401 gaccggtgat ttggatgaat tacatttaac aaatttgaac cattcattct ttgcagatat
     2461 cgcgcacaga ggtattggat ttttagcaag aaatcagtca ttttacgaac aagactttgt
     2521 tcgtttcttg caaaagaaaa tcaggcaaag taattttttg attgtcaatc atgcgttttt
     2581 aatacaagaa acacagcgaa aagaaccatt gcttccagct agtccatttt tgttgatcga
     2641 tgaagtacat catttgccgg aaatcgctga aaaagtaaat gacaaacgat taagtattaa
     2701 ctatttccat aaacaaatcc agcaattaga agaaccaaat cagctgtttg accgaataca
     2761 aagctattta ccgaaagaac atgaagcctt acgctggtta tcgatttatc gagaagaact
     2821 ttctgcgcta tgcgaagcac agatttgtat ggcagaagga ttaatgagtt tagtgagcgg
     2881 caagcaacct aacggacagt atccagaaga agtcatgatg acaaaagaga tgttggatca
     2941 gctgccactg gaatctggga cagccattga tcacctgcag cttttttatc aggagatcca
     3001 gcagctacag tcacaaatgc gtctgacttt tgagattatc caagaaagct ggacaaacca
     3061 gatgcggatc gatttagcaa gtttatatag cttatttgat caattagaca agcagtactt
     3121 gctgatggat caatggctgg aagactggcg agatcatttg atccattggt tcgttcctgg
     3181 gaacacagcg cagcagatga tttttcatct ccatgatttt caagcggcta tgttgccgtc
     3241 gactgtttgg tatcctcgat atgatcgtat tctttatatt ggaggaacgc tgaagatcgg
     3301 ccctaatcga cactatctct ctaagcggct tggcattgaa gcagcacctc ttaaagtgat
     3361 tgcctctcct tatgattatg agaaacaggc aaggatctat gtgccaaaag aggcacctgc
     3421 cgtccatcaa gtcagcaatc aagcatatat cgattattta gagacagcac ttacaggtct
     3481 tatcgaacaa gaagatcggc caatacttgt gttattcact tctcatgatg ttttgcagaa
     3541 ggtctatcag aaaatgcatc tgtctatgct agaaaaagga cgagaaatac tagctcaagg
     3601 gtttggcgga agccgggaga agcttttgaa acgcttcatt ttgtcagaaa aaagcgtatt
     3661 gtttggcgct gacagctttt gggaaggtgt agatttgcct ggggatgctt tgcagatcgt
     3721 tgtagtcaca cgtttaccct tcgataatcc gcttcgcccg atggtcaaag ctaggaacgc
     3781 ttatttagaa tcagagggga tcaatccttt ttaccaggaa tccgtaccta aagcagcttt
     3841 gaagttacgc caagcattag gtcgcttgat aaggacggag acagatcgtg gcgtattgct
     3901 tattttggat cgaagactag tcactgcaaa atatggtgca cggatcatcc atgcattacc
     3961 gaaaaaagta ccgatcaaag agctagctat ggaggaaatc tatcaggaca tccatgaatt
     4021 cttaaagaaa aatgaagaag gaagttagag gagctgtctt ttttcataat taaaatctgc
     4081 tataatgaaa aggaatgaag ataaaggagc gacgaccctt gaagaaaaaa cagacaaagg
     4141 aaaaaacgat taatcgcgtg ttacttggct tgatcgtatt tttattagcg gtcatcgtga
     4201 tcagctcgat tttttacttg cgttccagtc gtccggcggt gcaggcgaag aaagaagcag
     4261 tagaaatcgc aaagaaatat gcaaatcttg aggaagccga tcatttttat tggtttactc
     4321 gaaagaagac atacttttca ctgacaggta caaatgataa aggaaaagaa atcgccgtta
     4381 tcattcctaa atctggtgaa aaagtaaaag tattggatca aacaaaggga ctgactgaaa
     4441 acgaagcaaa acagacaatt gctgcggccc atcctgaaat ccaaatcgaa aaagctgctt
     4501 tagggatgta tgatgatcag cctgtgtggg aagtagtagg aaaagaaaca aatgggaaac
     4561 tgaattatta cctgattggc tttgaatctg gagatgaagt caagacaatc aagggaattt
     4621 aaaaggtaaa ggaatgaatg ggatggagtt atcaaaaaga acaaaacgat tagaaccgtc
     4681 tgtcactttg gcagctgcgg caaaggccaa ggcattaaaa gcaaaaggca gagatgtgct
     4741 gagtttgact gtgggagaac cggattttgc gacaccagaa aacatccaag aagcagcaat
     4801 cgaagcaatc cgcaacggga aagctagcta ttatacacca acagcaggaa tcccagagct
     4861 tcgacaggca atcgttgatt atctgaagaa aaactatgga cttgtctatg aaccttcaca
     4921 aacagtcgta acagacggag cgaaatttgc tttgtatacc cttttccaaa cgatccttga
     4981 cccgcaagat gaagtcatca ttcctgtgcc ttactgggtc agttacggtg agcaagtaaa
     5041 actggcagaa ggacttcctg tctttgtgaa aggggaagaa tccaatagct ggaaagttac
     5101 tgttgaacag ctagaacaag cacgttcaga aaaaacaaaa gccgtaatca tcaattctcc
     5161 atcgaatccg actggaatga tttatagcaa gaatgaactg caggcaatcg gtgaatgggc
     5221 agtaaaaaat gatattttga tagttgctga tgatatttat ggtcgtttag tttataatgg
     5281 caatgagttt actccaattg caacgatttc agaagcaatc aaaaatcaga ctatcatcat
     5341 caacggcgtg tctaaaacat atgcgatgac aggctggcgc attggttatg cggtgggaaa
     5401 tcctgtgatc atcaatggaa tgatcgctgt tgcttcccag tcaaccagta atccgacagc
     5461 agtcagtcaa tatgcagctg ttgaagcatt gaaaggcgag caagatacag tggaagaaat
     5521 gcggaacgcc tttgaagaac gcctgaatac gttatattcg cttgtggcag aactgccggg
     5581 tgtttctctt gaaaagccac aaggagcttt ttatcttttt cctaatgtaa aagaaacgct
     5641 acgcatgtgt aaatatgaaa atgtcacaca atgggtagaa gatcttttag aagaaacagg
     5701 ggtagcgctt gtgactggcg aaggctttgg ggcaccagaa aatgtccgca tgagttatgc
     5761 tactgatcgc gctacgttag aagaagcggt acgcagaatc aagcaattta ttgagagtaa
     5821 aagtcaaaat taatcctaaa gaaattcaag gaatataaaa ggagagtcat acgtggaaca
     5881 aattcaaatc atcgattcga aaaaccatgt gggagaaaca gtaacaatcg gcgcttgggt
     5941 cgcaaataag cgatcaagcg gaaaaatcgc atttttacaa ttaagagacg gaacagcctt
     6001 tttccaaggt gtagttgtaa aaagcgaagt gtcggaagaa gttttccaaa cagctaaaaa
     6061 tctacaccaa gaaacatccg tgttagtaac tggagaaatc cgtgaagaca gtcgttcaaa
     6121 atttggttat gaaatcggaa ttacaaatgt ggaagtggta agcgagagcc acgattatcc
     6181 gatcacacca aaagaacacg gaacagactt cttgatggat catcgtcatt tatggctgcg
     6241 ttcttcaaga caacatgcga ttatgcagat cagaaatgaa atcattcgtg caacgtatga
     6301 attctttaat caacatcatt ttgtcaaaat tgatccgccg atcttgactg gttctgcacc
     6361 agaaggcact acggatctat tcgaaacaaa ttactttgat caaaaagctt atttatctca
     6421 aagtggccaa ttatacatgg aagctgctgc tatggctttc ggaaaagtct tttcattcgg
     6481 tccgactttc cgtgctgaaa aatcaaaaac acgacgtcat ttgatcgaat tctggatgat
     6541 cgaaccagaa atggctttca ctcatcaaga agaaagttta gaagtacagg aacaatatgt
     6601 agcattctta gtacaaaatg ttttagatca ttgcgaatat gcattagatg tactaggacg
     6661 agacaaagaa gtcttaaaaa cttatacaaa attgccattc cctcgtatta cttatgatga
     6721 tgcgatcgaa ttactgaaga aaaatggatt tgatgacatc gaatggggcg aagactttgg
     6781 ttcacctcat gaaacgttca ttgcgaattc attcgaacag cctgtcttta tcctaaacta
     6841 tccaaaagcc atcaagccat tctacatgaa accacatcca acaagagaag acgtggtgat
     6901 ctgtgcagat atgatcgcac cagaaggtta cggtgaaatt attggcggaa gcgaacgggc
     6961 aacagactat gatttcttgc tagaacaaat ccgtaatcac ggtttggatg aaaaagaata
     7021 ttcatggtat cttgatctac gtaaatacgg ttctgttccg cactctggtt ttggtctagg
     7081 tcttgaacga acagtcactt ggattgctgg tatcgaccat gtacgtgaag ctattccatt
     7141 cccacgtttg ttgaaccgaa tttatccata agaggtgatg aaaaagctgt tctgcatcaa
     7201 gtaattagaa cagccaagca aaaacagctg ttcatgtttt tgaattggcg ggacttatta
     7261 ccgcagatgt aagcttttga ataccgttta gtggagaggt tgtgaaaaag ctgtttagtt
     7321 tcgagtatta agaaaaattt tgtggaaatg gctttccaca tttttgcata aatttggctt
     7381 aataccgaga aactggcttt tgaacaccgt ttaaggaaga ggttgtgcgc ctgccgttca
     7441 gctccgagtc acaaggagta atttcaaaaa acagtttttc atgtttgatg actattgtga
     7501 cttgtgaccg aggagttggc cggagagcac cgtttattct aaaaaagaac tgcgaactct
     7561 cgcagttctt tttttaaaat acgggataaa ggaagtttcc agcagacaag agaagaaagc
     7621 aaaagaaatt gctatttgat tcacaaggtt ctataacgaa atcgcaatca atcaaacatt
     7681 tacaaagaag gtaattcaaa tggaaatctg atttgatgat gcttctgctg ttgaaataaa
     7741 gcagcatcta gcacctgaaa acaaactaat agtaacattc gaagatggag taggtccgta
     7801 ttttcagcat gcaataatcc atatgtaagt tcaattcacc cttgaaatca tcggaccaga
     7861 taaagttatg accaatctat cccaagcaat ctagaagaga tattagtaaa gggacattta
     7921 ctagaagtct tagatgagcc tataaatata tgttctgatg gcgtcatcag tggtctgatt
     7981 gacggaagct taggtgtgat cgatctctct ggaccaaaca acgaaggaat caaggggaat
     8041 ccggcacgtt aagaaaaaaa tagcataaaa aactagacac ttgatgagcg ttcattcaat
     8101 tgtttgaagg gactaggctg gtgtcatttt ttatacatat attttctctt tcgtcttgat
     8161 agggcttatg ggataatata aggaagaaaa tcatcgtttt attcaaaaag gagtttttga
     8221 caaatgaaaa aacgtatatt atttatcggt gatagcatta cagacgcagg aagagaccga
     8281 gcagaagcaa ctgatctagg taaaggttat ccacttttga ttgccggaaa actaatctcc
     8341 caatatccaa cgatggaatt tgaatgcatg aaccgtggga taggaggaga caaaattgca
     8401 gatctgcaag tacgctggca agaagattgt ttagctttac aacctgacta tgtatcgatt
     8461 ttgatcggaa tcaatgatac ctggcataat actagcgatc aggctatatt cggaactgag
     8521 aaatctgctc agcaatttga atccgtttat cgaaaattac taaatgaact tcaaacagtg
     8581 ggaatctgca acatcatctt gatggagccg tttgtacttc ctataaccga cgaccgtcat
     8641 ggctggcgta aagacttaga ccctaaaatc caaattgttc gtaaacttgc taaggaatat
     8701 ggcgcattgc tggttccttt agatggtata ttcaatgctt tagggattgt ttatggtttt
     8761 tcgaaatata caagagaaga tggggtccac ccaacgattg gcggacatga gatcattgca
     8821 caaagctgga tagatgcaat tgccgcagtc gattttttta gtggagataa aaatgagcga
     8881 aagaaaagtg agaaatgatg gaaatacggt gggcagtaaa agaagatcta cctcaaatca
     8941 atcagctgat tactgatcat ccagaatcat tcgtaaaagc aaaaacggca gctgacctaa
     9001 atgataagaa taaactattg ctcgttgctg taacaaaaga aaaacggatt atcggatttg
     9061 cgcaagcgga cgtgcaacag tcagaagaac gattggatca gcgaccatca ggaaaactaa
     9121 tccaacacac attagtaaca aaagaaaata cggaagaaat ccaaaaaaaa tttgcagaat
     9181 atttgatact ggaagctaaa aaaagaagaa taaaatcatt ttttgcccag ttttaatcaa
     9241 aaacagtaat agaaggagaa atacaatgag ttgtttagga aatgtcatct ggtttatatt
     9301 cggcggacta atcggtggtc ttagctggtt agcagcgggg atactttggt gtatcacgat
     9361 cataggtatc ccaatcggta tgcaatgttt taagatcgcc tccctttctt ttgcgccttt
     9421 tggcaaagaa gtaatttatc accagtctgg catgtcattg attgttaata tcatctggct
     9481 gatcgtttca ggcctaccaa ttgctctcgc acatgtcgtc agcggcatcc ttctatgtat
     9541 cacgatcata gggatacctt ttgccaagca atctttcaaa cttgctcgat tggcgttgat
     9601 gccattcggt gcagaaattg tataaaagag aataataaag gttagataaa gcatagagtc
     9661 aggtgggata catgtatttc acctgactct atgcgttctc ctgtataagt tcttccatgt
     9721 gacttttacg tcttttattt atatggggtt actgtttatg gaaagttgaa ataattttca
     9781 ttaaagaact ctttctatat ttttgaaagc gtagtggagc ttcgaatatc tgggaaggac
     9841 attttgcagg gattgaaaaa agatattgtc ctatcgaaaa attaatgaat ttagacaaat
     9901 tgccagcaac aggcttcaaa cttagttgct atcctgtcaa gatcaagaag gcaagtgcgg
     9961 gttggataag agcagtggca atgatcgaaa agaaaaagaa agaataagcc aaaacatctg
    10021 tatggaagaa attttccgat gcagatgttt ttcatttttt ctttcggata ccttgacata
    10081 tgaataaccg ttcatttata attagttatg aagagatatt catatgttga ggcgaggagg
    10141 tcattaaaat gaaaagttac agattagaag gtttagattg tgcgaactgt gcaatgaaaa
    10201 tcgaaaaagg agttcagaag atcaatggag tcaaggaagc aacggtaaac ttcacttctg
    10261 gaaaactaac gattgacgca gaggaagatc atttggctac gattgaacaa gaaataaaaa
    10321 aagtagtgaa ggaattagaa ccagatgtca aagtaacaga aatagataag gaaaaagtat
    10381 ctgaacatgg aaatgaaaaa gagagaaata cgctgttccg gattttattt tcccttgcag
    10441 gtatcgcttt attgctatta tttgatttta atgaaccaat tcgcttgata gggtatttat
    10501 tgatttatct gctgatagga tatgatgtag tgaagaaggc agtgatgaat atcgtcaaag
    10561 gaaaaatctt tgatgagaat tttcttatgt ctgttgctac gattggcgct atgttgatcg
    10621 gtgaatatcc agaagccgta gcagtgatgc tattttatca aatcggcgag tatttccaag
    10681 gattggcagt cagtcattca agaaaatcga ttcgcgaatt gatggcgatc cgtccagaaa
    10741 cagctcacgt gcagacgacg gaaggattga tgaccgtgaa ccctgaagac gtgcagatcg
    10801 gtcagtttgt acttgtgaag cctggtgaac gtgtaccgtt agatggaacg atcatcgaag
    10861 gagaatcatt agtcgatacg tcagcactta caggagaatc agtccctaaa tctgtatatg
    10921 ttggtgaaac agtattaagt ggatttatca ataaaaataa accattttta gttcaagtag
    10981 aaaaatctta tgaaaattct actatcagca aattattaga attagtagaa aatgccagca
    11041 gtaaaaaagc accagctgaa aatttcatta ctaaattcgc gcgctattac acaccagtcg
    11101 ttgtaggatt ggccgtttta ttagctgttt tacctccact tgttgtttct ggagcggcgt
    11161 tttctgaatg gatctatcga gcattgacat ttttagtgat ctcatgtcca tgtgcattag
    11221 tgatctccgt accccttagt ttctttggcg gtatcggagg agcaagtaaa atcggtgtat
    11281 tagtaaaagg ttcaaattac ttggagttgc ttgcacaaac tgagacagtg gtattcgata
    11341 aaaccggcac attaacgaaa ggtgactttt cgatccagac gatcgataca aaaatcgatc
    11401 caaagatatt catgcaatat gttgcgagtg cagaacagtt ttctacacat ccgattgctc
    11461 aatctgtttt agaaggctac gcaggtccgc ttttaccaac agctaatatc caagaatttg
    11521 caggtgaagg gatcttagct gaagttgatg gcaaacaagt attagcaggt aatcacaaat
    11581 tgatggaaag atttgaaatc tcttttcctt caagtcaaga aatcggtaca ttgctttatc
    11641 tagcgatcga tcaaagttac agtggttatc ttgttattgc agataccttg aaagaagatg
    11701 ccgtagacgc attggttcaa ttaaaaaagg ctggtgtgaa gaacacagtc atgttgacgg
    11761 gcgattcgaa aaaaattgct gatcatatcg ggaagcaagt aggcgtggac aagatatata
    11821 gcgaattgct tccagaagat aaagtgcagc ggttagagga aatcttacaa agaaacaata
    11881 aaaagaccgc atttgtcgga gatggaatca acgatgcacc ggtgctagca agagcagatg
    11941 taggaatcgc aatgggtgga ttgggaagcg atgctgcaat tgaagcagca gatgtagtca
    12001 tcatgaatga tcaaccatcg aagattgcag aagcaatcca tttagcaaag aaaacattga
    12061 aaatcgtcaa acagaacatt gtctttgcta ttgggataaa aattttggta cttgccttag
    12121 gtgcttttgg ttttgcatca atgggagatg cagtatttgc agatgttggg gtgacagtat
    12181 tagctgtttt gaatgccatg cgaagcttgc atgtaaaaaa taaacgttga tcaatgaaga
    12241 ggacgaatga acgtcctctt ttttttatat ccttttctta atgaaaaatg taaagaaaat
    12301 agataggatt ataaaataac taatgttttt aattttgcag aaaattcaaa atagcttgaa
    12361 attcaataag gtaaatgaaa taaaagaaaa taacttattt ttttgatgga aaaaatatga
    12421 aaaaacgatg tgtattaaat aaaagaatac acacataaaa taacactgtc ttgtaagttt
    12481 gttaaaaatt gaatatgatt acatctggat aacaaatttt tatcataaag gagagaacga
    12541 atgaacaaca aacaattacg ctggtttact gttgcgttaa ttgcatttaa catggtttgg
    12601 ggcatgggga atgtagttaa taactatgct cagcaaggag tatcagttgt cacctcttgg
    12661 ctattgattt tggccattta ttttattcca tacgcattga tcgttggaca attagggtca
    12721 gccttcaagg atagtaaagg aggcgtcagt tcatgggtcg aaaatacgac atctaataaa
    12781 cgactggcat actatgccgc ttggacttac tgggtcgtcc atattcctta tttggcacaa
    12841 aagcctcaag caatcctgat tgctggcggt tgggcagtcc aaggaaatgg aaatatcgta
    12901 aatacgatgt cagtacaaat ggtagcagtt atttcactta ttatatttct tgccttttta
    12961 tatttatcaa caaaaggact ttctactttg aaagtgattg gcggactggc cggaacagcg
    13021 atgttcgtca tgtcgatctt atttattctt ttagctgtaa cggcaccgtt catcaatcca
    13081 acgatggaat ttgccacacc acatatgaat caagtgaaaa catatattcc aacatttgat
    13141 ttcagttatt tcacaaccgt ttcgatgcta gtatttgcag ttggaggagc ggaaaaaata
    13201 tccccttatg tcaactctac aagaaatcct gcaaaggaat ttcctaaagg gatgatcttc
    13261 ttagcagcaa tggtagggat ttgtgctgta ttaggctcag tcgcaatggg tatgctgttt
    13321 gctagcgata atattcctaa agacttgatg gcaaatgggg catacagtgc ttttcaaatt
    13381 ttaggtaatt actatggtat cggtaactca ttgatgatca tttacgcatt gacaaacatg
    13441 attggacaaa tctccgcatt agccttttca attgatgcac cactaaaaat cttgttagca
    13501 gatgcggatc cagaatttgt accaaactgg ctacgtaaac gtaatcgtaa aggtacattg
    13561 gtgaatggtt atcttctgac aggtatacta gtaggaatca ttattttgtt gccgatcttt
    13621 ggtatcaaag atatgaatga attagtaaaa tggttgacga acttgaactc agttgtcatg
    13681 ccaatgcgtt acctatgggt gttcttggca tatatgatgt tgaataaagc ttataagaaa
    13741 ttcaattctg aatataaatt tgttaaaaat ccaaaaatcg gttttatctt tggtgcttgg
    13801 tgctttgcct tcactgcgtt tgcatgtatc ctaggaatgg tgccaaaagt agattatact
    13861 gctgatccta aagcatggtg gttccaatta ttcacgaata tcatcacacc aattgtcttg
    13921 atcttattag gtatgatctt gccagcaatt gctcgtcgag acaaaaacaa agaaatcact
    13981 gaaccagaaa cagtggttca gccttaaaat agaaatactt gttacaagag gttgtgacag
    14041 aagtggtcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttctca aatttttgtg
    14101 aagtttcggc ttgtttttcg cagaagctac ttctggaaca ccgtgaatca gaggttgtga
    14161 aaaagctgtc ctgcatcaag taataagaac agccaaacaa aaatagcccc tcatattttt
    14221 cgttttgctg ggcttattac cgcagatgca agcttttgaa caccgtttaa gaaagaggta
    14281 gtgagcctgc cgtttaactc cgagtcacaa ggagcaattt caaaaaacaa cttctcatgt
    14341 ttgttgacta ttgtgccttg tgaccgaggt gttggcagga gaacaccgtt taaggaagag
    14401 gttgtaaaat cagcgatttg acctgagtat tagaggaaca aacgaaaaaa tagctcctca
    14461 tattttgccg ttttttgagt taatgctgaa ggtcagctga ttgaacacca tttattcgaa
    14521 acaagggact ttgacacgac ttttgtcaca gtcccttgtt tttttgcggc gttataagtg
    14581 gtatgatcga accaaattcc aaagagaagt gagggagaag aatgaagatc atcgtgattg
    14641 gacaaagtgg gtcgggaaaa tcgaccctcg caaggaagat caaagaaatc accgactttc
    14701 cgctactgcc gctagacctt ttatggcata caacagacta cagtattcag gcaaaaaagt
    14761 ggtttttgca agaacagcaa tcgtttatgg tatctaatcc gtcatggatt gttgaaggaa
    14821 attatacttc tacattagag gaaaggatta aagaagcaga taagatcatt tggcttaaag
    14881 tgccgcgtta tctcgccatc taccgagtag tttggcgttc tctaaaaaga aagataaaca
    14941 aaaaatctcg gccagatatg cctgaatcat tttcagagaa actaaacagg gaatacttag
    15001 aatttttatc ttttatctgg cattttgaag aaaacaatga accgaaaata cagcagctga
    15061 tccaagtagc taatgcaaga aataaactga tcatccttaa aacaagacga gagaaacaag
    15121 aatttttaac taaattgaaa atagagagca aaaataattg acagtttttg tttacaagcg
    15181 taatctgtat tcataagcta atgattacat ttgtaaacga aaggtgtgaa ataaatggaa
    15241 aaagtcaaaa cgccagtaaa gatcagtgat tcagagtggg agatcatgcg tgttatttgg
    15301 acacttggac agacgacagc ccaagaaatc acgcagatct tagctgattc gatggattgg
    15361 aaaccagcaa cgatcaaaac tttgctggga cgtttggtaa aaaaagaagt gatctggaca
    15421 gaacaagaag gaaaaaaatt catttatcat ccagctgtct cggagatgga aacagttcgc
    15481 agtgcgacgg aaaatctttt ttcccatatc tgtgcaaaaa ggattggaga gacgattgcg
    15541 gatctagtag aagaagccac tttgactcaa gaagatatca atgagatttt gaaacaactg
    15601 gaacaaaagc aaccagtaga tacgatcgaa tgtaactgta tcccaggtca atgtgaatgt
    15661 aaacaacatc aataggagga agaaaaaatg aaacaacaat tttcaatcga aggtatgagc
    15721 tgcaatcatt gtgcagcaag agtagaagaa acagtaagcg cacttgacgg cgtgcaaaaa
    15781 gtgaaagtaa atttgaaaaa agcaaacggt acggtcaagt ttgatgaaac aaaagttcaa
    15841 tccgaaaaga tttgtcaagc aatcaatgga ttgggttata aagcagaggt gatttgatgg
    15901 caacagcaga aaccaaaatg gatacgttcg tcattacagg tatgacttgt gcaaattgtt
    15961 ctgctaggat cgaaaaagag ctgaacggac aacctggtgt ggtcaatgcc acagtcaact
    16021 tggccactga aaaagcaagt gtcaaatatg aagggacgac cactgaaaaa ttaatccaaa
    16081 gcgtagaaaa catcggttat ggtgcaattt tgtacgatga agcccacaaa caaaaaattg
    16141 cagaagaaaa gcaagcgtat ttgaaaaaaa tgctattcga tcttatattg agtacggttt
    16201 tgactttgcc gttgatgttg tcaatgattg ctatgatgtt aggaagccat gcggcgattg
    16261 ttcacttttt tcattttcca atcgtccagt tagtgctgtc tgctcctgtc caattttatg
    16321 tcggtgctcg tttttataaa ggtgcgtacc atgcaatcaa gacgaaagca ccaaatatgg
    16381 atgtattggt agcaattgga acatcggctg cctttgcatt gagcatttac aacggatttt
    16441 tccgtggaca cccccaagat ctttattttg aaagcagcag tatgatcatc acgctgattt
    16501 tgctcggcaa atatttggaa catacagcaa aaacgaaaac aggtaatgca atcaaacaat
    16561 tgatgtctct tcaaacaaaa accgcccaag tgataagaaa cgggaaagaa gaaacgttag
    16621 cgattgaaga agtagtcgtt ggtgatcaac tagtcatccg tcctggtgag cagattccag
    16681 cagatggtcg aattatttca ggaagcagtg cgatagatga aagtatgctt actggtgaaa
    16741 atcttcctgt agaaaagaat ccggatgaca cgctttttgg cgggacaatc aatacgaatg
    16801 gtctgctaca catggaagtc acacaagtcg gcaagcagac agtattagcg caaatcattc
    16861 aaatggtgga agatgctcaa gggagcaaag ccccaatcca aaaaatcgca gatcggatct
    16921 cagggatttt tgttccgatc gtattagtca tcgcgtttat cacgctcata gctacaggtt
    16981 tgatcactgg tgattggcaa ctcgcattga tccatagtgt ctctgtatta gtcattgcgt
    17041 gtccatgtgc attaggttta gcgaccccaa cagctattat ggtaggaacg ggtgttggtg
    17101 cacgaaatgg aattttaatt aaaggcggag aagcattaga agcagctgct cacttagaca
    17161 gcattgtttt ggataaaact ggaacgatta cagaaggaaa gcccaaagtt acagatctag
    17221 tcggttcaaa agaagtccta tctatttttt atactttaga acaagcttct gaacatccac
    17281 taggtaaagc aatcgtggaa tacggaaaac tgcaagaagc agcaacatac gatatgattg
    17341 attttacagc ccacccaggt gctgggatca gcggtacgat taatggagta cgctattttg
    17401 cgggtacacg taaacgatta attgaattga acctatcatt tgatgaatac caagaacacg
    17461 cgttagaatt agaacagcag ggaaaaacag tcatgttttt agctgatgaa aagcaagtga
    17521 tcgggtggat tgccgtggct gatcaaatca aactagaagc caaacaagca atcaagcagc
    17581 tccagaataa aggattagat gtttttatgc tgacaggaga caacaaactg gcagccgaaa
    17641 cgattggtaa acaagttggt attgatccaa agcatatctt tgctgaagta cttccagagg
    17701 ataaagcagc ctacgtagaa aaacttcaga aagatggcaa aaaagtcggt atggcaggcg
    17761 atggaatcaa tgatgcaccg gccttagcat tagctgatgt cggtatggca atgggaagtg
    17821 gaacggacat tgcgatggaa acagccgatg tgacgctgat gaatagcagt ttggcatcca
    17881 ttgcacaaac aatcgagttg tctaggttga cattgagaaa aatcaaacaa aatcttttct
    17941 gggcttttgt ctataatacg attggtattc cttttgccgc actaggcttt ttgaatccaa
    18001 tcattgcagg aggagcgatg gcgtttagtt ccgtcagtgt attgttgaac tccctgagct
    18061 taaatcgaca catgaaaaag taagagaagg gatggagtaa aaatgaatgg gaacgatatg
    18121 gagaaaaaac atgagcataa aaaagaagta gtaaacaaag aaagtacaga atctcatgaa
    18181 aaacagatgg agatgaaaca tgaccatagt cagatggatc attccatgca catgggacat
    18241 aaccatggag atatagcaaa cagcaaacaa atggaccatt cgatgcacat ggatcacgaa
    18301 cacggcggca tggatcattc catgcacatg gggaatttca aacaaaaatt ttggctatcg
    18361 cttatcctag ctatcccaat cattcttttt tcaccaatga tgggaatgga atttccattt
    18421 caagtaacgt ttcctggttc tgattggctc gtattgatct tagcaactat actatttatc
    18481 tatggcggtc agccattttt aagtggagct aagatggaat tgaaacaaaa aagtcctgct
    18541 atgatgacac tgatcgcgat ggggattaca gttgcatata tttatagtgt ctattcgttt
    18601 atcgcaaatc tgctcaatcc acatacacac gtcatggatt tcttctggga attggctact
    18661 ttgatcgtta ttatgctact aggtcactgg attgaaatga atgctgtgtc gaatgccagc
    18721 aatgctttac aaaaactagc agaattactg ccagaatcag tgaaacgctt gacgaaagat
    18781 ggaaaagaag agacagtttc attgaaagaa gtaaacgaag gtgatcgttt gatcgtccgg
    18841 tctggtgata aaatgccaac agatggtgta atcttgaaag gtgaaacaat tgttgacgaa
    18901 tcagctgtga ctggcgaatc aagaggaatc aaaaaacaag ccaatgacaa agtgattggc
    18961 ggttctatca atggggatgg aacgatcgaa atcgaagtaa ctggaactgg tgaaaatggt
    19021 tatctagcga aggttatgga aatggtgcga aaagcacaag gagaaaaatc caagctagag
    19081 tcattatctg acaaagtggc aaaatggctg ttttatgtcg cattaattgt gggtatcctg
    19141 gcattcatcg cctggttgtt cttgacagat cttcctaatg cattagaacg tatggtaaca
    19201 gtctttatca tcgcctgtcc tcatgctcta ggtttagcta tcccattagt tgttgctcgc
    19261 tccacatcaa tagcagctaa aaacggatta cttttgaaaa accgcaatgc actggagcaa
    19321 gccaatgatc tagatgtgat catgctggac aaaacaggaa cactaacaga aggaaaattt
    19381 actgtaacgg gtgtcgaagt acttgatgat gcgttcaata aaaatgaaat ccttcaatat
    19441 ctaggagcct tggaagcgaa tgccaatcat ccattggctg ttggcattat gaattatttg
    19501 aaagaacatg aaatcaagcc ttatcaagct gaaaatctaa aaaatctttc aggagtcggg
    19561 ctagaggcaa cagtcaaaaa acaacaagtg aaaatagtta atgaaaaaga agttgagcgt
    19621 ctcggattaa acgtagaaca agcattattg aaaccttacc aagaacaagg aaataccatc
    19681 agcttcctga ttttagaaaa tcatctagct gcaatcgttg ctttaggtga cgtagtaaaa
    19741 acagaagcaa aagaatttat ccgaacattg aaagaaagaa aaatcactcc tgtcatgctt
    19801 actggtgaca ataaaaacgc tgcccaagca gtagcagatt atttagggat cgaagaatat
    19861 tatggcggtt tattaccaga tgataaagaa gctgttgtcc agaaatacct tgaccaaggg
    19921 aaaaaagtaa tcatggtggg tgatgggatc aatgatgcgc caagtttagc ccgtgcttca
    19981 atcgggatgg caatcggtgc agggacagat atcgcaatcg attctgcgga tgtcgtattg
    20041 acaaacagcg atccaaaaga tattttgcat tttcttgatc tagccaagca aacgcgaaag
    20101 aaaatgatcc agaacctctg gtggggggca ggttacaata ttcttgcaat tccgctagca
    20161 gccggaattc ttgcgccaat tggtatcata ttaagtccag cagttggtgc tgtcttgatg
    20221 tcgttaagta cggtagttgt agctctaaat gctttgacat tgaaaatcaa ataataatga
    20281 aaaaaggggc tctttgtcaa taaggactga tgggttgtac aaaatcaaat ctgggtcaga
    20341 atgaacctca ttctggctca gattttttgt tatcttactt tgattaattg attgatcaaa
    20401 aagattctaa ttctcatgtt ctcaaatgat ttaaatccgt aggatactc
//
LOCUS       DAPBCF010000047        20250 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.048, whole genome shotgun sequence.
ACCESSION   DAPBCF010000047 DAPBCF010000000
VERSION     DAPBCF010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20250
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.048"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            195..2237
                     /locus_tag="RD508_002108"
     CDS             195..2237
                     /locus_tag="RD508_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7736659.1"
                     /translation="MNKRIREILKLIIKNPEMKLSTLTSELDLTRRQINYAINQFNEE
                     LKTKNIPLIQRSHSGNITVPIEVIQMISQPDYDIGDDQELVVLTDSERQALIVMTLIA
                     NIDYISLDHLVDAVDVSKTTVMEDIKRTEPFIRNYSLTIRYNRMNGYQLVGSEHRILQ
                     LLSDLVKRFPIFRREMIRRKLAQDVSEEEIVHLIHNMEQMLHLSYSDESVDYLQTSAR
                     FLVSRGIKMSDKHAFFPDDVTDTPEFRMLMILVHETGWSLSKSYMEWFTLLFLTSNIF
                     ESKTTQNYDSDQELRKLISQMVENFQNQTLILIDDREDFERRILSHLRPACFRIRYNL
                     SLGVYSIDSLIKDSNHAILIDLMKELIIPIENWLNKAFPNDELDLLSYYFGYQLSNHN
                     KLNKQRQRAVVVCTNGVMVSKLVRANMEKLFPEIHFLASLSVRDFYKFEADYDLVFTT
                     TPLKSSMLQFMIEPIMTYQQQISLRYRVLSDLGITKVDRAMDELLTIIRKYANITNPV
                     SLREELQYFLIKEDGSTPLDNFNVLPSLTYYLRPSYVQIVEEEMSWERAVEVACRPLL
                     EHQIIDSRFIADCLDQIRQPGYAGYLGMKTCIPHTTVDKGVISDGVSILVCKKPIRFP
                     NGEDVSLILPLSFFDLTKHLRAINQIADIAKDDSLIEQLLIADDEKTVYQLLRQRS"
     gene            2248..2868
                     /locus_tag="RD508_002109"
     CDS             2248..2868
                     /locus_tag="RD508_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HDT7736660.1"
                     /translation="MRLADYPKLTVIMRGYTFDQADAILQAMQEFDHQFAVEMTMNTK
                     GALENIHELNQRYGDTTYIGAGTVRTLEQAQACYEAGAKFLLGPHMFTKEMLSYANKK
                     GLLAVPAAMTPSEVDRMFKEGADIVKVFPAAVVTPRFFKDIQAPLGKLPLMGVGGISK
                     ENAKEFFEQGASYLGLGSGMFNKQDIEELNVKNLARSMKELIEAIK"
     gene            2880..3338
                     /locus_tag="RD508_002110"
     CDS             2880..3338
                     /locus_tag="RD508_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7736661.1"
                     /translation="MELYLNEELVFRNVQAKTDSEVLAFLASEMYKKNYVKEEYIQAI
                     QEREKEYPTGLPSTPPGIAIPHANYEMVNKTTLAIATLKDPVLFHNMEDNNEQLPIQI
                     VIMMAIGEPHGQVEMLQKIVGIIQDEPLRQEMIRAGNDTELLELLKKAVF"
     gene            3357..3635
                     /locus_tag="RD508_002111"
     CDS             3357..3635
                     /locus_tag="RD508_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7736662.1"
                     /translation="MKRILVACGNGIATSTVVATKVREYLQQHGIDVSTTQTKLMEVP
                     GKVQDYDLLVTTGQFDGQTGGVPVIKGMPILTGIGADQTMEEILNLLK"
     gene            3660..5027
                     /locus_tag="RD508_002112"
     CDS             3660..5027
                     /locus_tag="RD508_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002386123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDT7736663.1"
                     /translation="MKIIMNVFNFFIDAGPTVMLPVIITIIGLIFGLKISRAFKSGLT
                     LGIGFAGIKLILDFMTTNVGPAAKAMVDRTGVKLDALDVGWGSIAAVTWASPIIPILI
                     FAILLVNIVLLILKRTHTLDVDIWNYHHMAIVGVIVYFVTKNVFLGVGASVVMAIATF
                     KISDWSQPMVESFFGIPGVSLPTVSALSSLVIAWPLNWLLDRIPLFRKSKFTIKDAQK
                     YLGFFGDSMIMGLVIGMVIGVLAGYDIKAVLQLGVSMSAVLVLIPKMTSLFMEGLMPI
                     SDAAQKWSQKKFKGTRLFIGLDAAVVVGNPDVITTALIIIPLTIALALVLPGNRVLPF
                     ADLAVVPFRVAMVVALTRGNLLKNIIIGLVVTASLLWCGSATAPMLTAIAKSVGINLG
                     TSSMLISSFAATSMIQSYLVFIAFAYKPIIGIPVLLLAFAGAWYYFDGIKKVNHEMDE
                     PLKAQ"
     gene            5042..6187
                     /gene="dgoD"
                     /locus_tag="RD508_002113"
     CDS             5042..6187
                     /gene="dgoD"
                     /locus_tag="RD508_002113"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HDT7736664.1"
                     /translation="MKISDVTVYKVKPRWIFVKISTDEGIEGWGEMISGTKTETVVAG
                     AYEIGNRLIGRNPFEIERLFQEMHRSFFRGGPINGTIVSGLEMALWDIKGKAFNVPVY
                     ELLGGAARDKIKVYSWIGGDRPSEVAEQAQDRFDRGFTAVKMNATEELHYIDSYQKVD
                     EVVERVASIRERFGDAMDIGVDFHGRVHKPMAKVLAKALEPFHPMFLEEVVLPENEEH
                     FKEVADSVAVPLATGERLYTRWQFKNLFKQGTVDIIQPDVALCGGILETRKIAAMAEA
                     YDMAVAPHAPYGPVALAATLQVDSCTPNVFIQEQSLGIHYNKGFDLLDFVKNKEVFQY
                     KDGYVDLPSKPGLGLEMDEDKIKEIAQEGLIWTNPQWKNYDGTIAEW"
     gene            6214..6705
                     /locus_tag="RD508_002114"
     CDS             6214..6705
                     /locus_tag="RD508_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736665.1"
                     /translation="MAEALMITVFLGLLIILQIIDQKKIIVFAQSSPVRKSLSILLTV
                     AILLIFWPEHLTDQIKLVAFASVILINGFLKEGLAKDSVVRFGVLNGNFNRYPQVQVE
                     KLGDDKSFISFYKSKNNSFSMIFDKDQTEMMDVFQELDIHSKITLDQSSEEKRAVVKK
                     DNE"
     gene            7148..8347
                     /locus_tag="RD508_002115"
     CDS             7148..8347
                     /locus_tag="RD508_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7736666.1"
                     /translation="MRDQTSGKMIRFYYTSLHFLYWMMFCSVYGFATLFLIYFKIDPA
                     KIGGILALVNIVSTVLQPFVSQVIIKKRKIPLITVLKTMIAGLGVILLAGVLIPNLPI
                     ITYILGGILVVSMQSFLNALAFEYSNTGYRINFGFSRAGGSFSYAVTSFLLGQLLAIY
                     SAAILPILVIVEAVIFFVILHLLPDVKNQEVFPMTKEQDRSVSLRKKYPFLILLFLGF
                     SFLFTFHTMINSFLAQIFENIHGGSKEVGIALMIAALCELPGMIFFEQLVKKKSSKFW
                     LSVASISFAVRGFMMLLASSILMMEMTHLLQAFSFALFIPASAYLFNQFLADDDRVFG
                     QTMIIIATTLGGVIGNVLGGSLLQHFGVWEMLIFGTGFAVLGALLTILGIRKIPKTGN
                     DSDSLVE"
     gene            complement(8842..9600)
                     /locus_tag="RD508_002116"
     CDS             complement(8842..9600)
                     /locus_tag="RD508_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7736667.1"
                     /translation="MDTKLSESEKYLWDFIQSHILEIPSYSIVKLSEYANVSTATVVR
                     TMKKKGYEGFTSFKHSLKEKENTNINFAALDKVDEGIKTAILKNEQEVIRTINMVESG
                     NIEDAIQRIKAARRIMIFARGFSELIAQEMMVKFQLTGKYCEMHTDPNIIKNISRKLS
                     KDDIVIFVSLNGETKELTTAAENCYKAEIGTILLTANRHSSLMEHIEIPFVGFKSEGS
                     FFPDYEVRSRLPLSILARILLDSYALRTSGFTQH"
     gene            9768..10703
                     /gene="pfkB"
                     /locus_tag="RD508_002117"
     CDS             9768..10703
                     /gene="pfkB"
                     /locus_tag="RD508_002117"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDT7736668.1"
                     /translation="MSVYTCTLNLAIDLFIETDEMKPSQVNRTNDDDIQANGKGVNVS
                     LIMKQLGIDSTALGFKAGFTGNYIEDYLHQKDISTDFISVPGMTRINVFTQVNKTNEE
                     FKLVNKGPEIPQEQIKTFLNQIQKLQADDYLCVSGSLPRGVSPEILIDISRICFENKV
                     HLIIDSSYPEIIDCLPYQPFLLKPNEEELQSWYNVELSDREGYIHYAERLIADGAKNV
                     LLSLGGEGGIFLNKDIVYSGNSPKGKVVNTACAGDTLLGTFLAGYLKGEQVDINLKKS
                     LAAGSSTAFRKGLTDFSDVAELEKQIEIKEGASKK"
     gene            10700..12145
                     /locus_tag="RD508_002118"
     CDS             10700..12145
                     /locus_tag="RD508_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7736669.1"
                     /translation="MTTYKIVAATGCPTGIAHTYMAQEALEQAAKRKGVSIKVETHGQ
                     VGIENELTPEEIKNADAVIIAADKDVQAERFAGKRVIDVPVSKGIKDADQLIEDALAG
                     KGSITAENKTVDAAGEKAEMGVAAGIGHSIYKNLMNGVSHMLPFVVAGGVIIAISFAI
                     WGVYSFDPNDPTYNPTAAMLKGVGDAAMGMMVPILAAYIAEGIAKRPGLVVGFVGGLL
                     ANSGGAGFLGGIFAGFLAGYFILLLQKVMKGLPKQLDGLKAIFLYPVIGVLFVGVVMS
                     LLANPMEAVNQGMMNFLAGFQNSNPLILGIIVGCMSAFDMGGPVNKAAYVTGTALLAQ
                     GNHTFMAGVSAACIAPPLITGFAALFFGKYFDTNDRNAGLVNFILGSTHITEGAIPFA
                     AKDPLRVLPTMMLGSSIAAVLTYMFGVQVPAPHGGFLVLPVVTGKVAWVGSILLGSIV
                     GGVILGLIQKRSVEKREAEAAAVEMKEATNN"
     gene            12173..12628
                     /locus_tag="RD508_002119"
     CDS             12173..12628
                     /locus_tag="RD508_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7736670.1"
                     /translation="MTLIKTNKVFMNKNFTTQDEVMNFLADQSIVLSISEDRDAVYEK
                     LMEREEESTTGMMDGFAIPHAKDASIKDADIVIVRLNGKVDWKSLDGEGTDFVIALFI
                     PDSEAGTTHLKFLSQVARLLMHKDVTEGLKQAQSAEEIAELLNQKLEEN"
     gene            12647..13621
                     /gene="lacD"
                     /locus_tag="RD508_002120"
     CDS             12647..13621
                     /gene="lacD"
                     /locus_tag="RD508_002120"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HDT7736671.1"
                     /translation="MPLTEKKKTYIRQLSNESGIISALAIDQRGALKKMIGKFQNKSA
                     TDEQIINFKKIISSELTPYASAILLDPEYGLPAAEVRDKNAGLLLAYEKTGYDASTPG
                     RLPDILSIWSVKRLKEQGADACKFLLYYDVDESDDINDQKKAFMERIGSECVAEDLPF
                     FLELVSYDANDPDTSSKEYALKKPHKVNEMMKEFSKPRYGVDVLKVEVPVNMNYVDGY
                     TKNEVAYTKEEAAAYFKEQSETTNLPFIFLSAGVTAELFQETLKFAKEAGSTFNGVLC
                     GRATWANGVEPFVTKGEYAAKEWMQTQGRKNIEELNNVLKETATAIKL"
     gene            complement(13732..14293)
                     /locus_tag="RD508_002121"
                     /pseudo
     CDS             complement(13732..14293)
                     /locus_tag="RD508_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364878.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            14437..15051
                     /locus_tag="RD508_002122"
     CDS             14437..15051
                     /locus_tag="RD508_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7736672.1"
                     /translation="MELAFKQLEKKDYKKAIQFAIKGMHFDWYTKNKLLLNLYGRYFW
                     YLELNRATQIIALYADDELAGVLLADIKGKSKKHHSFSQKLYVKLFDFLQNAFVKDSK
                     GGYDDTNDELLSDYLKKHSPDGEIVFLAANPDLKIKGIGSKLLKEFERREQGKEVFLF
                     TDSGCTYQFYERRGFERKKEKDNVMKILNKEVDLRCMLYSKIIQ"
     gene            15292..15675
                     /locus_tag="RD508_002123"
     CDS             15292..15675
                     /locus_tag="RD508_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7736673.1"
                     /translation="MPKYKEIALALKERIVEGKYQEGSKLPEQESLAREFKTSRVTIR
                     KAIQLLIDEGLLYTRRGSGTFIRSNIRQDNENVTQVNNVFGTSSQENTNVTSKIIRFD
                     VRFPTDYERRLSATYFRSPSCKSWV"
     gene            16038..16547
                     /locus_tag="RD508_002124"
     CDS             16038..16547
                     /locus_tag="RD508_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HDT7736674.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILEVFAEAELYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            16647..17297
                     /locus_tag="RD508_002125"
     CDS             16647..17297
                     /locus_tag="RD508_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736675.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEVRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            17748..18686
                     /locus_tag="RD508_002126"
     CDS             17748..18686
                     /locus_tag="RD508_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDT7736676.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            18699..19751
                     /locus_tag="RD508_002127"
     CDS             18699..19751
                     /locus_tag="RD508_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7736677.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            19809..>20250
                     /locus_tag="RD508_002128"
     CDS             19809..>20250
                     /locus_tag="RD508_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HDT7736678.1"
                     /translation="MTYVFLPKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISV
                     FGDVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILAVATVGLYGIGDCI
                     FTGLFSINTNESSWNLSTWIHNTGSGLGYAGFLLFPLLLVLLYRQ"
BASE COUNT         6417 a         3217 c         4277 g         6339 t
ORIGIN      
        1 accgaatatt taatattcac attagcccta aaataattgt cataccatgt tacatttgat
       61 ataacagcgt tcattttaaa aatagctgtt agtgtgacaa aacattaaac caagtgtgac
      121 aaaaaacgtg atgaaagctt tccggaaacg tatgtgaaca agtatataat gattttgtca
      181 ggaggatagt caaaatgaat aaacgaattc gtgaaatact caaactgatt attaaaaacc
      241 ctgaaatgaa actttccact ttaacaagtg aacttgattt gacacgtcgt caaatcaatt
      301 acgcgatcaa tcaatttaat gaagaattga aaacaaagaa cattccgtta attcagagaa
      361 gtcattctgg aaatattacg gtaccaatcg aggttatcca aatgatatca cagcctgatt
      421 acgacatagg tgatgatcag gaacttgtcg ttctcactga tagtgaaaga caagcattga
      481 tagtgatgac tctgatcgct aatatcgatt acatcagtct ggatcatttg gtagatgcgg
      541 ttgatgttag taagacgact gttatggaag atatcaaacg aacggaaccg ttcatcagaa
      601 attatagtct gacaattcga tataatcgga tgaatggtta ccaattggtt ggttcggaac
      661 accgtatctt acagctgtta tcggatctag taaaacggtt tccgattttt cgccgagaaa
      721 tgattcgcag aaaattggca caagatgttt ctgaagaaga aatcgtccat ttgatccata
      781 acatggaaca aatgttgcat cttagttatt ctgatgagtc ggtagactat ttgcagacat
      841 cagcgagatt tttagtaagc cgtgggatca agatgtcaga taagcacgcg ttttttcccg
      901 atgatgtgac ggatactcct gaattccgaa tgctgatgat cttggtacat gaaacaggtt
      961 ggagtctatc caaaagttat atggagtggt tcacgttatt atttttaact tccaatattt
     1021 ttgagagcaa aactactcaa aattatgatt cggatcaaga attgcgaaaa ttgatcagcc
     1081 aaatggttga aaatttccaa aatcaaacgt tgattttgat cgatgaccga gaagactttg
     1141 aacgtaggat actgagtcat ctgcgtccag cctgttttcg aatacgctat aacttgagtt
     1201 taggagttta ttcaatagat agtctgatca aggatagtaa tcatgcgatt ttgattgatt
     1261 tgatgaaaga attgattatt cctattgaga attggctaaa taaggccttt ccaaatgatg
     1321 aattagatct tttatcctat tactttggct atcaattaag taatcataat aaattgaata
     1381 agcaacgaca aagggctgta gttgtttgta ctaatggtgt catggtctca aagttagtac
     1441 gagccaatat ggaaaaactt tttccagaga tccatttttt agcttcccta tctgtgcgtg
     1501 atttctacaa atttgaagct gattatgatc tggtctttac tacgacgcca ctaaaaagtt
     1561 ctatgctgca gtttatgatc gagccaatca tgacatatca gcaacaaatc agtttacgat
     1621 atcgagtttt gagtgattta ggaattacta aggttgatcg agcaatggat gaattgttaa
     1681 caatcattag gaaatatgca aatatcacca atccagtttc gttgcgagaa gaactgcagt
     1741 actttttgat caaggaagat ggaagcacgc cgctggacaa cttcaatgta ttgccttcat
     1801 tgacttatta cttgcggccg agttatgtac aaatcgttga agaagagatg tcttgggaac
     1861 gagcagtgga ggtggcttgc cgaccgttat tggaacatca aatcattgac tcgcgtttta
     1921 tcgctgattg cttggatcaa atcagacaac cgggatatgc aggttacttg ggaatgaaga
     1981 cttgcattcc ccatacaacg gtcgataaag gtgtaatcag tgacggtgtc agcattttag
     2041 tttgtaaaaa gccgatacga tttcctaatg gtgaagatgt cagcttgatt ttgccgcttt
     2101 cattttttga tttaacgaag catctgcgag ccatcaatca aatcgctgat atcgccaaag
     2161 atgattcatt gattgagcag ttattgattg ctgatgacga aaagacagtt tatcaactat
     2221 taagacaaag atcttaagga ggaaaacatg agactagcag attatcctaa attgacagtg
     2281 atcatgcgtg gttatacttt tgatcaggca gatgctattt tacaagcaat gcaggaattt
     2341 gaccatcaat ttgccgtaga gatgacaatg aacacaaaag gagctcttga aaatatacat
     2401 gaactaaatc aacgttatgg tgacacgact tatatcggcg ctgggacggt aaggacatta
     2461 gaacaagccc aagcctgcta tgaggctggt gcaaaatttt tattaggacc acatatgttc
     2521 acaaaagaaa tgttgtctta cgccaataag aaaggattat tggcggtacc tgccgcaatg
     2581 actccttcag aagtcgaccg tatgtttaaa gaaggagctg atattgtaaa agtatttcct
     2641 gcagcggttg ttactccacg ttttttcaag gatattcaag cacctttagg taagttacca
     2701 ctaatggggg ttggtggaat cagtaaggag aatgcgaaag agttttttga acaaggtgct
     2761 agctatttag gtcttggttc cggtatgttc aacaagcaag acatcgaaga gctaaatgtt
     2821 aaaaacttag cacgttcgat gaaagaatta attgaggcta ttaaatagga gtgaggactt
     2881 tggaacttta tttgaatgag gaactcgttt ttcgaaatgt tcaagcaaaa acagatagtg
     2941 aagtcttagc gtttttagca agcgagatgt acaaaaaaaa ctacgtgaag gaggaatata
     3001 ttcaagcaat ccaagaacgg gaaaaagaat accctactgg attaccatca acaccaccag
     3061 gaatcgcaat tccccatgca aactatgaaa tggtcaataa aacaacttta gcaattgcga
     3121 ctcttaaaga tccggtccta tttcataata tggaagataa caatgagcag ttaccaatcc
     3181 aaattgtgat catgatggcg attggggaac cacatgggca agttgaaatg ttacaaaaaa
     3241 ttgttggaat catacaagat gagccactgc ggcaagaaat gatcagagca ggcaatgata
     3301 ctgaattatt agaactatta aagaaagcgg ttttttaata taaggaggaa atcataatga
     3361 aacgaatttt agtagcatgc ggaaatggta tcgccacttc aacagtagta gcaacaaaag
     3421 ttagagagta tttgcaacaa catggcattg atgtttcaac gactcaaaca aaattgatgg
     3481 aagttccagg aaaagttcaa gactatgatc tattggtgac gactggtcaa tttgatggtc
     3541 aaacaggtgg tgtaccagta atcaaaggga tgccgatttt aacaggtatc ggtgccgatc
     3601 agacaatgga agagattttg aacttactga aataatagct gatcaaagga gctgaaaaaa
     3661 tgaaaatcat tatgaacgtc tttaacttct ttattgatgc tggaccaaca gttatgttgc
     3721 cagtcatcat cacgattatt ggtttgattt ttgggttaaa gatttctcgt gcttttaaat
     3781 caggtttgac attaggtatc ggttttgccg ggatcaagtt gatattggac tttatgacga
     3841 ccaatgttgg accagctgcc aaggcgatgg ttgatcgaac tggtgttaaa ctagatgctt
     3901 tggatgttgg ctggggttcg attgcggctg ttacttgggc atcgccaatc attccaatct
     3961 tgatttttgc cattctattg gtcaatatcg ttttgctgat tttgaaacgt acacatacgc
     4021 tggatgttga tatctggaac tatcaccata tggcaatcgt tggtgttata gtgtattttg
     4081 tgactaagaa tgtcttctta ggtgtaggtg catcagtagt gatggcaatt gcgactttta
     4141 agatttcaga ctggtcgcaa ccgatggtag aaagtttctt cggaatccct ggtgtttctt
     4201 taccaactgt ttctgcgctt tcatcactgg ttattgcttg gccgttaaat tggctgctgg
     4261 atcgtatccc gttattcaga aaatcaaaat tcaccatcaa agatgcacaa aaatatttgg
     4321 gattttttgg tgattctatg atcatggggt tagttattgg gatggtgatt ggtgttttag
     4381 ccggctatga tatcaaagcg gttttacaat taggtgtcag catgtcagct gttttggttt
     4441 tgattcctaa gatgacttca ttatttatgg aaggattgat gccaatttca gatgctgcac
     4501 aaaaatggtc acaaaaaaaa ttcaaaggta cacgtttatt tatcggattg gatgctgcag
     4561 ttgttgtagg taatccagat gttatcacaa cagcattgat cattattcca ctaacgattg
     4621 cattagcttt agtattgcca ggaaaccgtg tgttaccatt cgcagattta gcggttgttc
     4681 ctttccgcgt ggcaatggtc gttgccttga ctcgtggtaa tttattaaaa aatatcatta
     4741 ttggcttagt tgtgacagct tcattgctat ggtgtgggtc agctactgcg ccaatgctga
     4801 cagcaattgc caaatcggtt ggtattaact taggaacttc ttcaatgtta atctcatcat
     4861 ttgctgcgac ttccatgatc caaagttatt tggtatttat cgcatttgct tacaaaccaa
     4921 tcatcggtat tccagtgttg ttattagcct ttgcgggcgc atggtattac ttcgatggta
     4981 tcaaaaaagt taatcatgaa atggatgaac cattgaaggc acaatagtag gagggtttaa
     5041 attgaaaatt tcagatgtca cagtgtataa agtaaaacca agatggattt ttgttaagat
     5101 ctcgactgac gaaggaatcg aaggctgggg agaaatgatc tcaggaacta aaacagaaac
     5161 ggttgttgct ggagcttatg agataggaaa ccggctgatt ggacgtaatc cgtttgaaat
     5221 cgagcgcctc ttccaagaaa tgcatcgatc tttcttccga ggcggtccta ttaatggaac
     5281 catcgtttcg ggtttagaaa tggctctgtg ggatatcaaa ggaaaagcgt ttaatgttcc
     5341 ggtttatgaa ttattgggcg gtgcagcacg tgataaaatc aaggtttatt cttggattgg
     5401 tggagatcga ccaagtgaag ttgcagaaca agcacaagat cggtttgatc ggggctttac
     5461 ggccgtcaag atgaacgcga cagaagagct gcattatatc gattcctacc aaaaagttga
     5521 tgaagtggtg gaacgagttg cgtctattcg cgaacgtttt ggtgatgcaa tggatattgg
     5581 tgttgatttt catggacggg tccataaacc gatggcaaaa gtgctagcaa aagctttgga
     5641 gccattccat ccaatgtttt tggaagaagt cgttttacct gaaaatgaag aacactttaa
     5701 agaagtagct gattctgtgg ctgtaccatt agctactggt gaacgcttgt acactcgttg
     5761 gcaattcaag aacctcttta aacaaggtac tgttgatatt atccaaccag atgtggctct
     5821 ttgtggggga atcttggaaa cccgtaaaat cgcagcgatg gcggaagctt acgacatggc
     5881 tgttgcgcct catgcgccat atggtcctgt tgcactagca gcaactctgc aagtagactc
     5941 atgtacgcca aacgtcttta tccaagaaca aagcttaggg atccactata acaaaggttt
     6001 tgatctgtta gattttgtga agaacaaaga agttttccaa tataaagacg gctacgtaga
     6061 tctaccttca aaaccaggtc tgggcttgga aatggatgaa gacaaaatca aagaaattgc
     6121 acaagaaggt ttgatttgga ccaatccgca atggaaaaat tatgacggta cgatcgctga
     6181 gtggtgataa atgaaaataa aggatgatga aagatggcag aagcacttat gatcacagtt
     6241 tttttaggac tgctgattat tttgcaaata atcgatcaaa agaaaattat cgtgtttgct
     6301 cagagtagtc ctgtaaggaa gagtttgagt attttactga cagtcgccat cctgttgatt
     6361 ttctggccgg aacatctgac tgatcagatt aaactggttg cttttgcttc tgtcattttg
     6421 atcaatggtt ttttgaagga gggtctagca aaagattctg ttgttagatt tggagtattg
     6481 aacggtaact ttaatcgata tcctcaagtc caagtagaaa aactaggtga cgataaatca
     6541 tttatttcat tttacaaaag caagaataat tctttttcaa tgatttttga taaagatcaa
     6601 actgaaatga tggatgtctt tcaagaactt gatatccatt ccaaaattac tttagatcaa
     6661 agttcggaag aaaaaagagc agttgtaaaa aaagataatg aatgattcta ctaccgaaat
     6721 tatgatttct ttatcacgaa taatgaaact tgttttaatg aatcatattg attgaagtat
     6781 acaatgtata ttaagttttg gaaagaaata tattggtaca agatatagca ggaatcgatt
     6841 actcgatccc tgcttttttt aacttccttt gcagcaaaaa aagctcgtaa tctaagagat
     6901 gatggatagt ttttagaata tatatatttt cttcaattcc agaaaaaaat gaccaagcta
     6961 gtatgctaaa aaagtacgat gcttctatga tcttttttcc gtctttatta acagatgttt
     7021 taattgatca acgcatattg taatctaccc taatttccat agttcttcac cacttttaaa
     7081 aatagtaaaa cccctacaag tatgctatag taaattgcta aagaaaaacc aataaggtgg
     7141 gagatgtgtg cgcgatcaaa caagcggaaa aatgattcgt ttttattata caagtttgca
     7201 ttttctttat tggatgatgt tttgttctgt ctatgggttt gcgacattgt ttttgattta
     7261 tttcaagatt gatccagcta aaatcggagg gatcttagca ttggtcaata ttgtttcaac
     7321 ggtgcttcag ccttttgtca gtcaagtgat catcaagaaa agaaagatcc cactgatcac
     7381 cgtgctgaag acgatgatag caggattagg agtgattctc ttagctgggg tattgattcc
     7441 gaatttgccg atcattactt atatcttggg tgggatttta gtagtttcta tgcaatcatt
     7501 tctcaatgcg ctggcatttg agtattcaaa taccggctac aggatcaact ttggcttttc
     7561 aagagctggt ggttcatttt cttatgctgt aacttctttt ttactgggac agctgttagc
     7621 gatttattct gccgcgattt tgccaatctt ggttatagtt gaagcagtga tatttttcgt
     7681 tattttgcat ctgctgccgg atgtaaaaaa tcaagaagtt tttcctatga caaaagaaca
     7741 ggatcgctca gtttctttga gaaaaaaata tcctttcctg attttgttat ttttaggttt
     7801 cagttttctt tttactttcc acaccatgat caacagcttt ttggcacaga tctttgaaaa
     7861 tatccacggc ggcagtaaag aagttggcat cgcattgatg atcgccgctt tatgcgaatt
     7921 accgggaatg atcttttttg aacagcttgt caaaaagaaa tccagcaaat tttggctgtc
     7981 tgttgccagt atttcatttg ctgtcagagg attcatgatg ctgctggcca gttcgatcct
     8041 gatgatggaa atgacgcatc tcctacaagc cttcagtttc gctttgttta ttccagcttc
     8101 ggcttatttg ttcaatcaat ttctggcgga tgatgatcgt gtatttggac aaacgatgat
     8161 catcatcgcc acaactcttg gtggggtgat aggaaatgtc ttgggcggca gtctgctgca
     8221 gcatttcggt gtatgggaga tgctgatttt cggtactggt tttgcggtgc taggtgcttt
     8281 attaactatt ttgggcattc gaaaaatacc gaagacagga aacgatagtg attctcttgt
     8341 tgagtagcat aaaaatactt agatactagt tttatataaa taacatatag tgattattgg
     8401 cgtaattaca aaaaacgaga ataacttaag taagcatttc taaataattg agaaacctca
     8461 tctaaaaaga taagaaaata tccctaataa aacttctgta acattttaga taactgattg
     8521 taatctgaat aataaactat aaggagacgg ttagacggtc tccttttttt gcgtattata
     8581 attctagaat tgttggaaat tgataataat taacaagaaa tattagacag gaacttcgaa
     8641 ctgcttatca cattcttatt attatatatt tgcgtaagta gtcctggtag tctcaatgca
     8701 ctattctatc ttgaaactaa gaagttatag aaggagcaat gatagaaagc acgagaatac
     8761 aaatagcgat taaatatttt tctagacaac cttagttaat tcacacagat atattttagg
     8821 tacagtctta cagatataga gttagtgctg tgtgaatcct gatgttcgca gtgcatagga
     8881 gtcaagtaag attctagcca gtatagaaag tggaagtctg gagcgtacct cataatctgg
     8941 gaagaaggag ccttctgatt taaagccaac aaaaggaatc tcgatatgtt ccatcaaact
     9001 tgaatgacga ttagcagtaa gcaaaattgt cccgatctca gctttataac agttttcagc
     9061 tgcggtagtc aattcctttg tttcaccgtt tagtgaaaca aagatcacga tgtcatcttt
     9121 ggataatttt ctactaatgt tttttatgat attgggatca gtatgcatct cacaatattt
     9181 accggtaagt tgaaatttga ccatcatttc ctgagcaatc aattctgaaa aacctcgggc
     9241 aaaaatcatg attcttctag cagccttgat tcgttgaata gcatcttcaa tattcccgct
     9301 ttctaccata ttgatggtgc ggattacctc ttgctcattt ttaagaatag cagtctttat
     9361 tccttcatca actttatcaa gagcggcaaa attgatattt gtattttctt tttcttttaa
     9421 cgaatgttta aaagacgtaa acccctcata tccttttttc ttcatagtac gaacgacggt
     9481 tgctgttgaa acgttggcat attcacttag ttttacaatg gaataggagg ggatttcgag
     9541 tatgtgactt tgaataaaat cccagagata tttctccgat tcacttaatt ttgtatccat
     9601 attttgcctc cgattagtta ggataattct attgtaaagc gggagtttcc tttacttcaa
     9661 gtttatttaa tatattttgt aaaagttttc aatgaattta gtcatttatg aaaacattta
     9721 cattcgatct tgatacataa tgaatatgta agaaaggagg agcgtaaatg tcagtttata
     9781 catgtacttt aaacttggca atcgaccttt ttatcgaaac agatgaaatg aaaccatccc
     9841 aagtcaatcg aacaaacgat gatgatatac aagctaatgg aaaaggtgtg aatgtttcat
     9901 tgatcatgaa gcaattaggt atcgatagta cagctttagg atttaaagca ggttttaccg
     9961 ggaattatat tgaggattat ttgcatcaaa aagatattag cactgatttt attagcgtac
    10021 cgggaatgac tagaatcaac gtttttacac aagttaataa aaccaatgaa gaattcaaat
    10081 tggttaataa aggacctgag attcctcagg aacaaatcaa aacttttcta aatcaaatac
    10141 aaaagctgca agctgacgat tatttgtgtg tttctggcag tttgccgcga ggggtctcac
    10201 ccgaaattct tattgatatc agtcgtattt gttttgaaaa taaggtccat ctgattattg
    10261 attcaagcta tccggaaata attgattgtc tgccgtatca gccgttctta ttaaaaccaa
    10321 acgaggagga attgcaatct tggtataatg tcgagcttag tgatcgtgaa ggatatattc
    10381 attatgctga acgcttgatt gccgatggag cgaaaaatgt tctcctttct ctaggaggag
    10441 agggaggaat atttttaaat aaggatatcg tttattctgg gaattctcct aaaggtaaag
    10501 tagtcaatac agcgtgtgct ggtgacactt tgttgggaac atttcttgca ggatatttaa
    10561 aaggtgaaca ggtagatatt aatttgaaga aaagtttagc agctggaagt tcaaccgctt
    10621 ttcgtaaagg attaacagat ttttcggatg ttgcagagtt ggaaaaacaa atcgaaatca
    10681 aagagggagc gagtaaaaaa tgacaactta caaaattgtt gccgcaacag gatgtccaac
    10741 aggaattgcc cacacttata tggctcaaga agcattggag caggcagcta agcgcaaagg
    10801 ggtatctatc aaagttgaaa cccatggtca agtagggata gagaatgaat taacaccaga
    10861 agaaataaaa aacgctgacg ctgtaatcat tgcagctgac aaagatgttc aagcagaacg
    10921 tttcgcaggt aagcgtgtaa tcgatgtgcc tgtcagcaag gggattaaag atgctgacca
    10981 attgatcgaa gatgcgttgg ctggtaaagg ttcaatcact gcagaaaaca aaacagttga
    11041 cgctgctggt gagaaagcgg agatgggggt tgcagcaggc attggtcaca gtatttataa
    11101 aaatctcatg aacggtgttt ctcatatgct gccgtttgta gtggcaggtg gggtaattat
    11161 tgcaatttcg tttgccatct ggggtgtgta ctcttttgat cccaatgatc ctacttacaa
    11221 tccgactgcc gctatgttaa agggtgttgg tgatgcggca atgggaatga tggttcctat
    11281 tttagcagct tatatcgctg aaggaatcgc taaacgtcct ggtttggttg ttgggtttgt
    11341 tggcggactg ttagccaatt ctggcggagc cggtttctta ggcggaattt ttgcaggttt
    11401 cttagcaggc tactttatct tactattgca aaaggtcatg aaaggcttgc ctaaacaatt
    11461 ggatggtctg aaggcgatct tcttatatcc ggtgatcggt gtcttgtttg ttggtgtagt
    11521 catgtcttta ttagcaaatc caatggaagc agtcaaccaa ggaatgatga atttcttggc
    11581 aggattccaa aattctaatc cattaatttt agggattatc gttggctgta tgtcagcatt
    11641 tgatatggga ggtccagtca ataaagcggc ttatgttaca gggactgcgt tgttggcaca
    11701 aggtaaccat acatttatgg caggggtttc ggcagcttgt atcgcgcccc cattgattac
    11761 tggatttgcc gcactgtttt ttggaaaata tttcgacacg aatgatcgca acgctggttt
    11821 agtcaacttt atcttgggct caacgcacat taccgaagga gcaattccat ttgcggctaa
    11881 agatccgctg cgtgttctgc caactatgat gctaggttca tcaattgctg ctgtactgac
    11941 atatatgttt ggtgtccaag ttcccgcacc tcatggaggt tttctagtat tacctgttgt
    12001 tactggtaag gttgcatggg tagggtcgat tttacttggt tcaatcgttg gcggagtaat
    12061 tttagggttg atccaaaaac gtagtgtaga aaaacgtgaa gcagaagcag ctgctgttga
    12121 aatgaaagaa gcaaccaaca actaaaggtt attctagaaa gaaggatttc aaatgacttt
    12181 gatcaaaaca aataaagttt ttatgaataa aaattttacg acgcaagatg aggtaatgaa
    12241 cttccttgca gatcagtcaa ttgtcttgag cattagtgaa gaccgagatg cagtttacga
    12301 aaaattgatg gaaagagaag aagaaagcac gactggtatg atggatggtt ttgccatccc
    12361 tcatgccaaa gatgctagta tcaaggatgc cgatattgtg attgttcggt taaacggtaa
    12421 ggtcgattgg aaaagtttag atggagaagg aacggatttt gtaatcgctc tgtttattcc
    12481 agattcagag gctggaacaa cccatctaaa atttttatct caggtagcca gacttttgat
    12541 gcacaaagat gtgacagaag gtctgaaaca agcccagtct gctgaagaaa tagctgaact
    12601 tttaaaccaa aaattagaag aaaactaaaa aggaagtagt gaaatcatgc ctttaacaga
    12661 aaaaaagaaa acttatattc gtcaactaag taatgaaagt ggcatcatca gtgcgttagc
    12721 aatcgatcaa cgtggtgcct tgaaaaaaat gatcggtaaa tttcaaaata aatcagcaac
    12781 cgatgaacaa atcatcaatt tcaaaaaaat catttcttct gaattgactc catatgcttc
    12841 agcaatctta ttagatccag aatatgggtt gccggcagcc gaagttcgcg ataaaaatgc
    12901 tggtctgttg ttggcctatg aaaaaactgg ttacgatgct tcaactccag gacgtttacc
    12961 ggatatttta tctatttggt ctgtaaaacg tctaaaggag caaggggccg atgcttgtaa
    13021 gttcttgtta tactacgatg tagatgaatc tgatgacatc aatgaccaaa agaaggcgtt
    13081 tatggagcgg attggttctg aatgtgttgc tgaagatttg ccatttttct tagaattggt
    13141 ttcttatgat gccaacgatc ctgatacttc ttcgaaggaa tatgccttga aaaaaccgca
    13201 taaagtaaat gaaatgatga aggaattttc taagcctcgc tatggagttg acgttttgaa
    13261 agtggaagtt cctgttaata tgaactatgt ggatggttac actaaaaatg aagttgctta
    13321 taccaaagaa gaagctgctg cttatttcaa agaacaatcc gagactacca acctgccatt
    13381 tattttcttg agcgcaggag taactgctga attgttccaa gaaaccttga aatttgcaaa
    13441 agaggctggc tctacattca atggggtact ctgtgggcgc gcaacttggg cgaatggtgt
    13501 agaaccattc gttactaaag gtgaatatgc tgccaaagaa tggatgcaga cacaaggacg
    13561 caagaacatc gaagagctga ataatgtttt gaaagaaaca gcaacagcta ttaaattgta
    13621 agaaagcttt aactataacc ttaagtttgt aacctaatga tttttaataa tcaatttgag
    13681 cttttaaata aagaattgga agcgtcccga cgcttccttt ttcgtttgtt tttaaggcat
    13741 gataggttct atgttgtcgt tcaataagcg caagaaggtc agcatttttt tcttagagta
    13801 tgcaaaattg cttttctacc caatgattta aaacggagag gcacccttgg atatggtaga
    13861 tggtgaagta acgcatttct tctgtgatca cggttttttt gtcttcttgt agccagattt
    13921 ttaaataatt ttcttcgatc agattattta atctcttttg aaattggata tctccgtggt
    13981 tgatgacgaa taacttgtat acgaacgtat tcgtatagac atagtcgatc aattgagcgt
    14041 atagatcctc gtagctatgt gtcgtatcgt aggaaatgat ttcatccaag tcttggaaaa
    14101 agctattttc cagtttttca taaagatcat agatatccgt ataatgtgta taaaatgtcg
    14161 aacggtgaag atcagcagtt tcggtcagtt cacggatggt gatgttttga atttttttat
    14221 ctactaataa ttttgataat gcttctgcta acgctttttc tgtttttttg acgcggcgat
    14281 cctctttttt cattttgcag cctcctaatc aacataatca aggaattgtg tcggttatcc
    14341 gacaatttca ccgctatctg aacatagata accgacacct tgtctattat aatataagta
    14401 tagcatatca atatttaaag aataggagaa taagtgatgg aattagcctt taagcaactg
    14461 gaaaagaaag actacaaaaa agccattcaa ttcgcgatta aaggtatgca ctttgattgg
    14521 tataccaaga acaaactcct tttgaatctt tatggaagat acttttggta tctagaattg
    14581 aatcgcgcga cacaaatcat tgctttatat gcggatgatg agttggcagg tgttttatta
    14641 gcagacatca aaggaaaatc aaaaaagcat cattcattta gtcaaaagtt atatgttaaa
    14701 ctatttgatt tcttacaaaa tgcatttgtg aaagacagca aaggcgggta tgacgacacc
    14761 aatgacgaat tgctttcaga ctatttaaaa aaacattccc cagatggaga aattgtcttt
    14821 ttagctgcca accctgattt aaagatcaag gggatcggta gtaaattatt aaaagaattt
    14881 gaacgccgag agcaaggaaa agaagtattt ctgttcacgg atagcggctg tacgtatcaa
    14941 ttttatgaac gacgcggttt cgaacggaaa aaagaaaaag ataacgtcat gaagatcctt
    15001 aataaagaag tagatctccg ctgtatgtta tatagtaaga tcattcagta atgtttttta
    15061 ctatcagaaa gcagaagtac cacgaaggtc aatggaaaaa gcgagtaatt gatccattta
    15121 gatgaagata ggtgtagtct caaagatatt agctggcaaa gatatcccca gttaaaaata
    15181 gatttctgta tccaacaata aaaatatttt tgtatttatt agtatatata ctttacaaaa
    15241 atttgtatat atactaattt ttttgtagga tcaatgaaat gaggggaaaa tatgccaaaa
    15301 tataaagaaa tagccttggc tctaaaagag aggatcgttg agggaaaata tcaggaaggt
    15361 tctaaattac ctgagcaaga aagtctggct agagagttta aaacaagccg tgttactatc
    15421 cgcaaagcta tacaactcct tattgatgaa ggtttgttat atacgagacg tggatctggt
    15481 acttttatac gaagcaatat cagacaggac aatgagaatg tcactcaagt aaataatgta
    15541 tttggcactt cctcacaaga aaatacaaat gtgacaagta aaataatccg ttttgatgtc
    15601 cggtttccga cagattatga aaggcggctt tctgcaacct acttccgatc cccttcctgc
    15661 aaatcatggg tataaaaaat aggcatatta agcgggctag gaggagaaat attcacatat
    15721 cattttttca ttccgcaagc tgcgtcaagt tatttggaat ttgtagaaca gatgagagag
    15781 gtagaagcag cactacaaac tacttttcaa taagtaggaa ttatagaaat tttactcaaa
    15841 aaatcttcat taaaaaatct gactaaataa gttgagaaaa cagaatatac ttcaatatcc
    15901 agtgatttat aaatatcatt cactcatgat acccagctcc gtatcataag tgatgcggtt
    15961 tttatcattg atcctaaaaa tcttagcaag acaaaaagta cgtaagaaag taaagactaa
    16021 atacttcgga ggaacaaatg aataacaatg ataggttatt gcgattgcgt tatgcgattg
    16081 atttgaaaga tacggatttg attaaagctt ttgagctagg cggtgtacca ctgactaaag
    16141 aagaagctca ggcggtactg accaaagtac aggataagaa caaagataat gcagaaaata
    16201 atgtgtatga aaaaaccatc aacaaccaag tttttgacgc attcctaaat ggcctgattc
    16261 tcttggcgcg tggtccgcaa aaagataagc cgatagtaga cacgccgcaa aaaagcaagg
    16321 aaatcaaata tatcaacaat gtgttgctaa aaaaattaaa aatcgccttg tctatgacca
    16381 ctgatgatat tttagaagtt tttgctgagg cagaactcta tccatcaaaa ggcgaaatcg
    16441 gggcattttt gagaaaagaa ggccaacgaa attttaagcc ttgcggagat aaatatatgc
    16501 gtaattttct caaggggtta ggaatttata atcggagaaa agtataaaga aatttcatga
    16561 gaaatcaaaa caatggttgt tttgatgaga gctagttttt gtatgagatt aaaatattat
    16621 cttaatcgag gagctggatt ggttttatga atgatgaata taagaatgat gaagataaga
    16681 tgctttttga agagatagag aatcgatgta ggctcaattt tgagcttcgg ggaaagatgt
    16741 ctttaataca acaaaaaaag tatttagcga ataaatcaga gtttactctg ggacatgttg
    16801 aaaaattaat ctcggattgg attagtagta gaagcgaatt tacaaaaata aaacagccga
    16861 ttaaatttga catgaaaaaa cttttgttaa ataagagtga gataggtaat agagatcaat
    16921 atattagagc taaagggcaa gaaataattg attcattagg tgaagtgagg tcatacaatt
    16981 atttgtatgt aacacataga gctgatggaa tggtcattac tgtggggaaa tcttcttcta
    17041 atgatatttt tttagatgga gatctttttt atcaactcaa tacaaatcac ttgtctggca
    17101 ctgaaaatat aattttaagg acggaatatg gcaatgaaat atttgcaaaa tatgatgaga
    17161 ttttaaaaaa ttatttggac tgggcttgga taattccggt tgagtcagga gatgctaaga
    17221 aactggagag attattgggc gatgaactaa ttaataaaaa agtaccaatt ttaaattatt
    17281 attcccatag acaataaaag gctatttttc atgataatac tagttataac tgtaaaaatg
    17341 gaagaaaatc tgggaaagaa gtttttaaat aagtgtattg ttcgatttta ataaataata
    17401 agcaatacca tccgtctgtg ttgcgcaaca tcgtactaca atgaatattt tttcacaaaa
    17461 agaaaatcat ccatcgaatg aatggaaggt tttagtatac acgaggttaa tgtcccctct
    17521 tttataatca gaggagtgag gttttttcta tgaatgtttc tattttctta ttgctagtct
    17581 agtttctctt acgatgaaat tgggattcta ttccagtttt tattgatttg ctgataaaat
    17641 aacttgaatg gtggatataa acatgataaa taagagaaga ataacaaaac aaggttgtga
    17701 aatgattctc aaataagtat aatagaaaga aaaaggagga agaatcaatg aaaatagcaa
    17761 ttgcaggcgc tggcgcaatg ggaagtcgct ttgggttaat gcttcaccaa agtgggaacg
    17821 aagtattatt aatcgatggc tgggcagaac atgtccaaca aatcaaagaa catggattac
    17881 aagcaaattt taatggtaaa gaggtagaag caaaactacc aatcgttctt caatccgaag
    17941 tagaaaaaga agatcaagtt gatctgatta ttctatttac caaagcgatg cagctggaaa
    18001 aaatgctgca ggatatccaa tcattaatca aaaaagatac agaggtctta tgtctattaa
    18061 atggtatcgg gcatgaagat attattgaga aatttgtacc aatggaaaat atctatattg
    18121 gaaataccat gtggacggca ggtcttgaag gtcctggtca ggtcaaatta tttggaagtg
    18181 gttcagtaga attacaaaat ttaggtgatg gaaaagaagc agctgcaaaa aaattagcag
    18241 acaaattgtc tgaatcagga ttaaatgctc atttttctga caatattcac tattctattt
    18301 atcgcaaagc atgtgtgaac ggaacaatga acggactatg cacaatctta gacgttaata
    18361 tggctgagct aggaaaaaca tcgactgctc ataaaatggt ggcgacgatt gtcaatgagt
    18421 ttgccaaagt agcagcagta gagaagattg aactagatgt cccagaagtc attgcacatt
    18481 gtgaatcttg ttttgacccg gaaacaattg ggttacatta tccttcaatg tatcaagact
    18541 tgattaagaa ccatcgatta acagaaatcg attatatcaa tggcgcaatt tctagaaaag
    18601 ggaagaaata tggtgttgcg acgccttatt gtgatttctt gactgagctt gtccatgcaa
    18661 aagaagatag tttgaacgta aaataaagga gagattgaat ggaaacttca caaaaaatat
    18721 caccgaaaat ttttctgaat aaagtcctcg ctggtacagc aacaggaatc attattggat
    18781 tgattcctaa tgcagtatta ggtgctattt taaaatattt tagtgcgtat ccctttgcgg
    18841 taacgatcgc acagttagca gttatttttc aattagcaac acctttgatc attggtggtt
    18901 tgattgcctt acaatttgga tttgatccga tgagaatgat ggttgtagcc ggagcttctt
    18961 ttgttggttc tggtgtagtc aaattcacac ctgatttggg tgaaacgggt gtttacgttg
    19021 gtgctggtac aggcgatatt attaatacga tgctgacagc atcgattgct gtcgggctga
    19081 ttttactgat tggaaatagt tttgggtcag tgtcgattgt gttaacaccg attgttgtag
    19141 gtgtaggtgc aggtttactt ggtttttatt tattcccttt tgtaacagca attacttctg
    19201 caattggatc attgattaat aacttcacta ccttacaacc gctgttaatg tctatcttga
    19261 ttggttgttc ctttgccttt ttgattatct ctcctatttc aacagtagca atcggaatgg
    19321 caatccaact agatggtgtt tctgctggtg cggctgcgat gggcgtagct gcaaccactt
    19381 ttgttttagt agtgaactct tggaaggtta ataagtcagg tgtgacaatt gcgattgctt
    19441 taggcgctat gaagatgatg atgcctaatc tatttagaaa acctgtgatt cttattcctt
    19501 gtttagttag tgcagtgatt acagctattc ctgtcgctct attttctatt tcaggtacgc
    19561 ctgcttctgc tggtttcggt gtggtcggac ttgttggtcc gttggcttct ttagatgcag
    19621 ggctaaatgg ctttcttgtt gttctttgtt ggttagtcat ccctgttttt gcggcactaa
    19681 ttactcaatt tttatgcgag aaagtattta aactgtatga tcgagaagaa gtcttcaaat
    19741 ttttaggcta gtagatttta ctaagaaatt ttcaatcaat ggatgcgtaa gtgagatgtc
    19801 aacaacatct gacttacgtt tttttgccaa aatatggttt ttatttttta ttattaggtg
    19861 tgattagtga tttatcgaca ccgtatatcc ttggcctttt ttatcccaaa ctgaatcaaa
    19921 tgactaccgt aattagtgtg tttggtgacg tagatagtcc agtcagacgt gctttcttgg
    19981 tctggtcagt tgtatctgga cttttttttg ttctttcgtt gcctgcgttg tatcacctat
    20041 ttgttggaac atcaaaaaca cttgcaatac ttgctgttgc aacagttggt ttatatggga
    20101 taggtgattg tatttttact gggttattca gtatcaatac gaatgaaagc tcttggaatc
    20161 tatcgacttg gatccataat acaggttctg ggctaggcta tgcaggcttt ctacttttcc
    20221 cattgttact tgttctgctt tatcgtcaaa
//
LOCUS       DAPBCF010000048        19996 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.049, whole genome shotgun sequence.
ACCESSION   DAPBCF010000048 DAPBCF010000000
VERSION     DAPBCF010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19996
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.049"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            4..816
                     /locus_tag="RD508_002129"
     CDS             4..816
                     /locus_tag="RD508_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HDT7736679.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            813..1613
                     /locus_tag="RD508_002130"
     CDS             813..1613
                     /locus_tag="RD508_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDT7736680.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1774..3042
                     /gene="rseP"
                     /locus_tag="RD508_002131"
     CDS             1774..3042
                     /gene="rseP"
                     /locus_tag="RD508_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HDT7736681.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3110..4819
                     /locus_tag="RD508_002132"
     CDS             3110..4819
                     /locus_tag="RD508_002132"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDT7736682.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5031..9383
                     /locus_tag="RD508_002133"
     CDS             5031..9383
                     /locus_tag="RD508_002133"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HDT7736683.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            9527..10000
                     /gene="rimP"
                     /locus_tag="RD508_002134"
     CDS             9527..10000
                     /gene="rimP"
                     /locus_tag="RD508_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDT7736684.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10024..11199
                     /gene="nusA"
                     /locus_tag="RD508_002135"
     CDS             10024..11199
                     /gene="nusA"
                     /locus_tag="RD508_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDT7736685.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNSKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11221..11514
                     /locus_tag="RD508_002136"
     CDS             11221..11514
                     /locus_tag="RD508_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HDT7736686.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11511..11822
                     /locus_tag="RD508_002137"
     CDS             11511..11822
                     /locus_tag="RD508_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HDT7736687.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11835..14141
                     /gene="infB"
                     /locus_tag="RD508_002138"
     CDS             11835..14141
                     /gene="infB"
                     /locus_tag="RD508_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDT7736688.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14168..14515
                     /gene="rbfA"
                     /locus_tag="RD508_002139"
     CDS             14168..14515
                     /gene="rbfA"
                     /locus_tag="RD508_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDT7736689.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14623..14844)
                     /locus_tag="RD508_002140"
     CDS             complement(14623..14844)
                     /locus_tag="RD508_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7736690.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            15292..17655
                     /locus_tag="RD508_002141"
     CDS             15292..17655
                     /locus_tag="RD508_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HDT7736691.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKLGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRNDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFHSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAATLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            18023..18946
                     /gene="truB"
                     /locus_tag="RD508_002142"
     CDS             18023..18946
                     /gene="truB"
                     /locus_tag="RD508_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDT7736692.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            18950..19891
                     /gene="ribF"
                     /locus_tag="RD508_002143"
     CDS             18950..19891
                     /gene="ribF"
                     /locus_tag="RD508_002143"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HDT7736693.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKKDEQATAEYFSQQ"
BASE COUNT         6862 a         3513 c         4389 g         5232 t
ORIGIN      
        1 agaatgttac gtttttttcc gcaaaaaaac aaatatattc aagaaaaaag cgaatttcaa
       61 tttaataccg atggaccaat tcctcagcac attgccatca tcatggacgg caatggtcgt
      121 tgggcgcaaa accgtcgttt gccacgagtt gctggccata aagaaggcat ggaaacagta
      181 aagaaagtca caaaaaaagc atcaaggctt ggagtgaaag tgttgacgct ttatgccttt
      241 tcgactgaaa actggaagcg accaaaagat gaagtaagtt ttctcatgca actacctgtc
      301 gacttctttg atacgttcgt accagaattg attaaagaaa atgtcaaagt tcatgtcatg
      361 ggttatgaaa acgtattgcc agaacatacg caagatgctg taagacgtgc aattgagcaa
      421 acaaaaaaca atactggaat ggtattgaat tttgctttga attatggaag tagagcagag
      481 atcgtgactg ctgtccaaga aattgccgaa gaagtagcaa aaggagaaat acacgcagaa
      541 gaaatcgatg atgaattgat tgctaagcat ttaatgacag gtttcttgcc taaagagtta
      601 caagatcctg agctgatgat ccgtacaagt ggagaagagc gaattagtaa ttttctgtta
      661 tggcagatcg catatagtga gctgtatttt acaaaagcgc tttggcctga ttttgatggt
      721 gcgcatcttg aagaagcaat cgcctcttat caaaatcgag accgtcgatt cggcggtgta
      781 aaaaaaacag aagatgagaa aggggatcag tcatgaaaca acgtgtgatc acagcagctg
      841 tggcgctagt cttgtttatt ccgattatat ggatcggagg catagcggtt gagcttacag
      901 cagcaatctt agcggtagta ggagtttacg agctgttccg gatgaaagga ttgacactct
      961 taagttttga aggagtttta tccgccgttg gtgcagtgtt acttgttttg ccaaaagaaa
     1021 gatggttttt ctttcttcca gagaatgtaa gtacatttat gttattttat cttatagtta
     1081 tgattctttt aggaacatca gttatttcta aaaatacgta tacgattgat gaagcaggtt
     1141 ttcctgtgct tgtcagcttg tatgtgggaa taggtttcca gaattttgtc aatgcacgaa
     1201 cagaaagctt ggctgttttg atatttggtc tatttattgt ttgggcaact gatatcggag
     1261 catatatggt tggtcgacgt tatggtcagc ataagttaag tcctgatatt tcgcccaaca
     1321 aaacgattga aggtgcgctc ggtggtatcg gtagtgctgt tgtagtcgca tttctttatt
     1381 tattgctata cccagcaaaa gaactattca atcatggtat gtttgtcatg cttctgatga
     1441 cgattatttt ttcagcagtc ggacaatttg gtgatttggt cgaatctgca atcaaacgtc
     1501 attatgatgt gaaagactcg ggaaatatct taccaggcca tggtggaatc ttagaccgtt
     1561 tcgacagttt gctgtttgta tttcctatca tgcatttatt tggcattatt tagtaagtat
     1621 acctgcgttt ctttgtgaat ttcataaaag acgcaggttt ttatttttca ttatattgat
     1681 actattggtg tctttggtat actatggtaa aattatagtg ttttatcgtt gttttataaa
     1741 aaacacaaaa aacaagtaaa ggagaaaaaa gctatgaaaa cgattctgac atttatcatc
     1801 gtttttggta tattagtgat tgttcatgag tttggtcatt tcttctttgc gaaacgatca
     1861 ggaatcctcg tccgcgaatt tgctatcggt atgggtccga aaatttatgg gcatcaagca
     1921 aaagacggga caacatatac gcttcgccta ttacctattg gcggttatgt tcgaatggca
     1981 ggcaatgggg atgatgaaac agaaatggca ccaggaatgc ctctttctct tttactaaat
     2041 tctgacggca tcgtagagaa gataaattta agtaagaaaa tccaattgac aaatgctatc
     2101 ccgatggaat tgagccgtta tgatttagaa gatgagctga ctatcactgg ttatgtgaat
     2161 ggagacgaaa cagaagtagt aacctaccct gttgatcacg atgcgacgat tattgaaaac
     2221 gacggaacag aaatcagaat tgcgccaaaa gacgtacagt tccaatcggc taaattgtgg
     2281 cagcgtatgc tgaccaactt tgctggaccc atgaataact ttattttggc aatcgtgtta
     2341 ttcatcattc tggcatttat gcaaggtggt gttcaagtga cgaacactaa tcgcgtagga
     2401 gagatcatgc ctaatggagc tgcggcagaa gcaggcttaa aagaaaatga tgaggtagtc
     2461 agtgtggacg gaaaagaaat ccattcatgg aatgatctga caacagtcat tacgaaaaat
     2521 ccaggtaaaa cattagactt taagatcgaa cgagaaggtc aggtgcaatc tgtcgacgtg
     2581 acaccgaaat ctgtagagtc aaatggcgaa aaagttggcc aacttggtat aaaagcccca
     2641 atgaatacag gttttatgga taagatcatt ggagggacgc gtcaagcttt cagcggttca
     2701 ttggaaattt tcaaagcctt aggatcacta tttacaggtt tcagtttaga taaattaggc
     2761 ggacctgtca tgatgtacca attgtcttca gaagcagcaa atcaaggtgt aacaactgtt
     2821 attagtttga tggcgcttct ttcaatgaat ctcggaatcg tcaatctgct tccgattcct
     2881 gccttagatg gcgggaaatt agtcttgaat atttttgaag ggattcgcgg gaaaccatta
     2941 agtcaagaaa aagaaggaat attgacatta gctggctttg gatttttaat gttgttgatg
     3001 gtgctagtta catggaacga tattcaacga ttctttttct agaaaaagtt gacaaatagg
     3061 gtataataac aaacgataac tattttgagg aaataaagga gtatatagaa tgagacaatc
     3121 aaaaatgttg attccaacat tacgcgaagt tccaaatgat gcagaagtat taagccatca
     3181 aatcttgcta agagctggat atatccgcca agtatcagcg ggtatttatt catatctgcc
     3241 attagcaaat cgtgtattgg aaaaactgaa acgcattatg cgggaagaat ttgaaaaaat
     3301 cggagcggta gaaatgctga tgcctgccat cttgccagca gaactttggg aagaatccgg
     3361 gcgttacgaa acatatggac caaacttgta tcgtttcaaa gaccgcaatg atcgaaaaat
     3421 gatccttgga ccaactcacg aagaaacttt tactgatttg atgcgtaatg aaatcaattc
     3481 atataagaaa ttacctttaa atctttatca aatccaacct aaatatcgtg acgaaaaacg
     3541 acctcgcttc ggtttgcttc gcggaagaga gtttatcatg aaagatgcat attctttcca
     3601 tgcaacggaa gaaagtttgg acgagacata taaagattac gaaaaagcct ataccgaagt
     3661 attcaagcgt tgtggcttag aatttcgctc gatcatcgga gacggcggcg caatgggcgg
     3721 gaaagactca aaggaattca tggcgatctc agaaatcggg gaggatacga tctgttattc
     3781 gactgaaagt gattatgctg caaacttgga gatggctaca agctactatg tatcaaaaaa
     3841 atcgcatgaa acacagcttg aattggagaa agtagctaca cctaacgtaa aatcaattga
     3901 cgaagtagca gatttctttt ctgttgaacc tcaaaaaatc atcaagtctg tattgttcat
     3961 tgcggatgaa caacctgtcc ttgttttggt acgtggagac catgaagtca atgacgtaaa
     4021 actgaaaaac tttttatctg ctgacttttt agaagaagca acagaagaag aagcacaaaa
     4081 atatctaggt gctgagtttg gttctgtcgg accagtcggt gtttcagatg acgtaaaagt
     4141 atatgcagac cgttatgtcc aagatttagc gaatgccatt actggagcga acgaaacagg
     4201 attccactat aaaaatgtga atccagaacg cgatttcact gtgctttctt atgaagatct
     4261 tcgttttgta caagaaggag atccttcacc agacaacaac ggtgttcttg cctttactcg
     4321 aggaatcgaa atcggacata tattcaaaat cggcactcgt tacagtgaat ctatgggagc
     4381 aactgtacta gacgaaaatg gacgagaaaa atttgtgatt atgggctgtt atggtatcgg
     4441 tgtaagtcgt ttattatcag caatcgtaga acaacattca gatgaacaag gaatcaattg
     4501 gccaaaagga attgcgccat ttgatctgca tatcgtccaa atgaatctaa aagacgaata
     4561 ccaaacaagc ctgacgaatg aactagaaga agcgatgaca aaagctggct atgaagtact
     4621 ggttgatgac agaaatgaac gcgcaggagt gaaattcgcg gattctgatt tgattggctg
     4681 tccaatcaga atcactgtcg gtaaaaaagc agtggatgga atcgtagaag tgaaaatcaa
     4741 gaaaactggc gaaatggttg aagtacgtaa agaagaattg gcgaatactt taccaatcct
     4801 cttgaaccaa ggcgaataat aagcgttaaa acacagaaaa taaaaatagc tgaatcagct
     4861 gtttttgaca atctgatgat tcgcttttaa aattggaact gcgatttgaa tcgcagttcc
     4921 aattttttaa tgtaaaactc agaaaaaacg agtatactaa aaggtactga aaaagaagag
     4981 gataagatgc gatcaattgc attgtttctc atcagaaagg gcgtatatct ttgtcagaaa
     5041 aacgagattt atttgaaaaa ctgttggaac aaatccaact agaggaagca gaaaaaaatc
     5101 atccactgct tactgctggt gaaatggata gtgtagtggt ccatcgtaaa tcgcgtttat
     5161 gggaatttac gctacatttt tccaaaattt tgcctattat gctatatcgg tcattgactc
     5221 agcatctgac tatcgctttt aaagatattg cacaagtcaa actgaatatc ttagcagatg
     5281 accagacatt cgatgaacag ctcttgcaag attactgggc ccaagctttg gaaaatcagc
     5341 aatgcgatac accactagca cagcaagtat tgaaaacgca ggtacctgtg ataaaagatc
     5401 gtaaagtcat cttgccaatc gacagtacag gagctatttc ttatttgaag caacaatact
     5461 tgccattagt agaagagttg ttcgtcagtt acggattccc aaaatttcgt atcgaaccag
     5521 aagtggatga gcagcaagcg gaacgtgtat tgaaactttt tgaagaacgc aaacaagaac
     5581 aggcagaagc ctttatgaag caagcagctg aaagtctagt tgtccacgaa caaaagaaaa
     5641 aggaaagaaa agagcaatcg ccagctcttg aaggacccat ccagctagga cgaaatattc
     5701 cagccgatga accaacgaca ccaatgatca gtatcgttga agaagaacga agagtcacac
     5761 ttgaggggta cgtattcgac aaagaagtca gagaactacg ttcaaaacgc aagatcttga
     5821 ctttgaaaat cacagattat acttcatcat ttatcgtcaa aaaattctcg aacggcgaaa
     5881 aagatgaaca agtatttgat gcgatcagtg tcggtagctg gttaaaggta cgaggaagta
     5941 ttcaagaaga tacgtttgtc cgtgatttgg tcatgaatgc gcaagatatc atagaagtca
     6001 aacatacacc tcgcaaagat tatgctcctg aaggggaaaa acgagtagag cttcatgttc
     6061 atagcaatat gagtacgatg gatgcaacaa acagcatctc tgatcttgtg gcacaagcag
     6121 gaaaatgggg acaccgagct atcgccatta cagaccatgg tggtgcgcaa gcctttccgg
     6181 aagcacatag tgctggaaaa aaagcaggtg tgaaaatctt atacggcgtg gaagcgaatg
     6241 tcgtagatga tggtgtccca attgcttata atgatgcaca tgaagcattg agtgaagcca
     6301 catacgtcgt atttgacgtg gaaacgacag gattgtctgc agtatatgac acgatcatcg
     6361 agctagccgc agtcaaaatg tataaaggaa atgtgatcga aagctttgat gaatttatcg
     6421 atccaggaca tccattgtca cgaacaacgg tagatctgac tggtatcacg gatgaaatgg
     6481 ttcgagggtc aaagtcggaa gaagaagtat tgcggatgtt ccttgaattt tcaaaagata
     6541 caattttggt agcccacaac gcggcttttg atatggggtt cttgaatact agctacgcaa
     6601 ggtatggtat tcctgaagcg gccaatccag tcattgatac gttggaatta gctagatatc
     6661 tgtatcctca attcaaacgt ttcggattag gtgtgttatc taaaaagttt ggtgttagct
     6721 tggaacagca tcaccgagca atctatgatg ctgaagcaac tggtcactta gcatggatct
     6781 ttgtgaaaga ggcaatggac aatcataaca tgctttatca tgatcagcta aatgagcata
     6841 tcggagaagg agattcttac aaaagggctc gacctttcca tgtaacgatt ttagcaaaaa
     6901 atcaggcagg actgaaagat ttgttcaaac tgatttcaat gtcgaatgtc gaatacttcg
     6961 aacgcgtccc acgaatacca cgctcccaat tgaaaaagat gcgtgaaaat ctattgatcg
     7021 gctcagcttg tgataaggga gaaatattcg aagccatgat gcaaaaaggg gtagaagagg
     7081 caagaaaccg agcaaaattc tatgattata ttgaagttat gccaaaagcg gtctatgcgc
     7141 ctttgatcga gcaagaattg gtaaaaaatg aacatgattt ggaagaaatt atccaaaatt
     7201 tggtagaaat cggaaaaagt ttggataaaa tcgttgttgc aacaggtaat gtacattatc
     7261 tgaacgaaga agatgccatt taccgaaaaa ttttgatcaa ttctatgggc ggagcgaatc
     7321 cgttgaatcg tcatagtttg ccggatgtcc atttccgaac aaccgatgag atgctaactg
     7381 catttcactt tttaggggaa gaaacagcga aagagatcgt agtagaaaat acgaataaaa
     7441 tcgcagatat ctgcgaagaa gtgattccag tcaaagatga actttataca ccgaagattc
     7501 caggttcaga agatgaaata tcagaattga gttacacaaa agcaaaacaa atgtacggag
     7561 atccgttacc tgagatcatt caaaaacgat tagaaaaaga gttgaattct attaatggta
     7621 atggcttctc ggttatttat ctgatcgccc aaaaactagt gcataaaagt aatgaagatg
     7681 gctatctagt aggttcacgt ggctctgttg gctctagctt tgttgcgacg atgacaggaa
     7741 tcactgaagt taatccatta gcccctcatt attattgtcc agagtgccaa tattccgagt
     7801 tttttgaaga tggtacgtat ggttctggat ttgacatgcc agaaaaacaa tgtccaaaat
     7861 gtggtgcacg cttaaacaaa gacggtcatg atattccatt tgagacattt ttaggattcc
     7921 atggagacaa agtgcccgat attgatttga acttctcagg tgattatcaa gcagaagccc
     7981 ataactatac gaaagtattg tttggcgaag actatgttta ccgtgccgga acgattggta
     8041 cagtcgccga caaaacagca tatggctatg taaaaggata cgaaagggac aataatctgc
     8101 agtttcgaag tgcagaagtc gacagattag caaaaggcgc tactggagtc aaacggacaa
     8161 ccggccagca tccagggggg atcatcgtta ttcccgatta tatggatgtc tatgatttta
     8221 cgccgatcca atatccagca gacgatcaaa attcagaatg gaaaacgact cattttgatt
     8281 tccactcgat tcacgataat gtattgaaat tagatattct agggcatgat gacccaactg
     8341 ttattcggat gcttcaagat ttatcaggga tcgacccaca aacgatccct acggatgacc
     8401 cggaagtgat gcggatattt gccggtcctg aagtacttgg agtaagtcag gaacaaattt
     8461 attccaaaac agggacatta ggtattccag aattcggcac tcgttttgtt cgagggatgt
     8521 tagaagaaac gcatcctaca acttttgcag aactactgca aatttccgga ctatctcatg
     8581 gtacagacgt atggttagga aatgcggaag aattgattcg acgaggagat gcgacactgg
     8641 cggaagtaat cggctgtcgt gatgatatta tggtttattt gatccatgct ggattagata
     8701 gcgggatggc atttaaaatc atggaaactg ttcgtaaagg acaatggaac aagatccctg
     8761 atgaattgcg agaaacctat ctatcggcga tgaaagaaaa taatgtgccc gactggtata
     8821 tcgattcttg ttcaaaaatc aaatatatgt ttccgaaagc ccatgctgca gcttacgtat
     8881 tgatggctct tcgtgtcgct tatttcaagg tttatttccc tattttgtat tactgtgcat
     8941 acttttctgt acgtgcagac gactttgatc tagtctccat gtgcaaagga aaagatgctg
     9001 tgaaacaagc aatgaaagaa atcacggaca agggattaga tgcttccgta aaagaaaaga
     9061 atcaactgac agtgctggag ttagccaatg aaatgctgga acgaggattc aaatttggaa
     9121 tgattgattt gtataaatcg gatgccgtta actttgttat tgaaggtgat acgttgatcg
     9181 caccatttag agctgtccca agtttgggaa ccaacgtggc gaaacaaatc gttgaagcaa
     9241 gaaaagacgg tccattttta tccaaagaag atcttgccac ccgcggtaaa gtttcaaaaa
     9301 cattgatcga atatatgaac gacaatggcg tattgaaaga tctaccagat gaaaatcaat
     9361 tatcgttatt cgatatgcta taagcatctg ttttcctgtc tgcttgtaat tttaagcaga
     9421 gtatggtata gttcttatag gtaatgatac taactgtgag tgagcggatt tttcgctcac
     9481 tctttttaat ggaattacgc acttaatttt taaggaggcg aaacttttga gtagcgtcgt
     9541 tgaaacagtc acagaaatgg tgacaccgat tttagatgaa caaaattttg aacttgtcga
     9601 agtcgaattt gtaaaagaag gaaaaagctg gttcttacga gtatttattg acaaagaagg
     9661 cggtatcgat atcgaagaat gcgcctttgt cagtgagaaa ctgagtgaaa aacttgatgc
     9721 agcagatcca gatccgattc ctcaagctta tttcctggag gtatcctccc cgggagcaga
     9781 gcggccattg aaaaaagaaa gcgactatga aaaggcactt ggtgattatg tccatgtctc
     9841 cttataccaa ccagtagatg gcgaaaaaca atatgaagga tttcttcaat catttgatgc
     9901 tgaacagctt acattgaaaa tacgcataaa aacacgagaa aaagaattga cttttgaccg
     9961 aaaaaatatt gcaaaagctc gcttagctat ccaattttaa tcacggagag gaatcagaaa
    10021 aaaatgagta aagaaatgtt aaatgcgtta gacgctttag aagctgaaaa agggatctca
    10081 aaagaaatcg tgatcgatgc attagaagca gcattggttt ctgcatacaa acgtcactat
    10141 ggccaagcac aaaacgtcga agtggaattt gatcagaaaa aaggaaagat ccatgtctat
    10201 gcggtaaaag aagtaacgga agaagtgatg gattcacagt tggaagtctc attgaaagat
    10261 gcacttttaa tcaatccagc atatgagatc ggtgatacga tccgttttga agtaacacca
    10321 aaagattttg gacggatcgc tgcgcaaacg gctaaacaag ttattttaca gcgtgtacgt
    10381 gaagcagaaa gaacgattat ttataacgaa ttcagtgctt atgaaaaaga catcatgcaa
    10441 ggaatcgtcg aacgccagga taaacgttat atttatgtca atcttggtaa aattgaggca
    10501 gttctttcta aacaagatca aatgccaaat gaattttatc aaccacatga tcgaatcaaa
    10561 gtttatgttt cccgagtaga aaatacgtct aaaggtccgc aagtatttgt tagccgcagc
    10621 catccagacc tattgcgtcg cttatttgaa caagaagtac cagaagtcta tgatggaatc
    10681 gttgaaattg tcagcatcgc ccgtgaagct ggcgatcgtt caaaagtggc agttcgctca
    10741 aatgatccaa atatcgatgc agtcggtaca tgtgtcgggc caaagggaca acgagttcaa
    10801 gcaatcgtca atgaattaaa aggcgaaaac atggatatcg tcgaatggaa tgaagatcca
    10861 gctgtattca tcgcaaatgc attgaatcct gcacaagtca tggatgtgat cttcgatgag
    10921 acaaattcaa aggcctgcac agttgtcgtt ccagactacc aattatcgct agcaatcggt
    10981 aaacgcggac aaaatgcacg tttagctgct aaattgacta accataaaat cgatatcaaa
    11041 tcagaatctg acatgacgga attttatgaa aatcaagaac aacaaaaaga aacagaagaa
    11101 ctgcatgatg aagcaatcgt tcagtcagat ttaacagacg atgaatatga aacaattgca
    11161 ttcaacaatg aaacggtcga agaaaaacca gaagcttaac tttagtaagg aggcaaagag
    11221 atgaaacaaa ggaaaattcc tttacgcaaa tccgtggttt caggtgaaat gaaacctaaa
    11281 aaagagatgg tccgaatcac ccgttcaaaa gaaggggaag tatcgatcga tccaactgga
    11341 aaaatgcctg gacgaggagc gtatgtctca cttgagccgg aagaagtaca acaagcttgg
    11401 gataaaaaaa ttctcgatcg agtactcgaa acaacattaa cagatgagtt ttatcaagaa
    11461 cttcttgact atgtcactca ccaaaaagca cgtaaagagt tatttggaaa atgaatacag
    11521 ttaatcggca aaaagccatg aatctcatcg gtctagcgat gcgcgcggga aaactaatca
    11581 cgggtgaaga actgaccatt gctgaaatcc gcaaacaaaa agcaaaattg gtgtttgtgg
    11641 caaccgatgc aagtgagaat acaagaaaaa agataaaaga taagagttca tattatgaag
    11701 ttccttgctt tgagctattt tctgaagcag aaatcacgca gatgatcgga aaacctcgca
    11761 aggtattcgg aataatggat gccggatttg cgaagaagac caaggagcta attgaaggtt
    11821 aggaaggtga ttgcatgggc aacaaaagaa tctatgaatt agcaaaagaa ctcaaaaaat
    11881 ctagtaaaga cgtcgtggaa aaagcacaac aacttggcat cgatgtgaaa aaccatatgg
    11941 gtgcgattac tagcagtgat gagaagaaat tgcaacaagc gttcaaaaac ccaagcacga
    12001 aacaacaagc tgcacaacaa gcaagcagaa aaccagccaa tcaacagccg aacgatcaac
    12061 gtaaaaaaga aacaacgaac aatcaacaaa aaaataaaaa taaccgcagt tatcaagatc
    12121 gcggtcaagg gagcggtcaa gtgaatcaag gaaaaaaacc aacaacaaac caaaataata
    12181 cgggaaatac cagcagccaa aatcgtcaag gaacgagcca aggcggcaat caaaaccgta
    12241 ctaacaataa caacaaacca aacaataaca atcgcggcaa atttaataat aataaccgta
    12301 atcgttataa taaaaaaggt aaaaaaggca aacagcaaca atcaactaaa ccagctgtac
    12361 caccacgcaa attccgtgaa ttgccagatg tattagagta tactgaaggt atgaacgtag
    12421 cagatattgc gaaaaaaatt catcgtgagc cagcagaaat cattaaaaaa ttatttatgc
    12481 ttggtgtcat ggtcaatcaa aaccaagcac tggataaaga tacgattgaa ctgttagcga
    12541 cggactatgg catggaacca caagaaaaag tccaagttga cattgctgat atcgataaat
    12601 tcttcgaggc agaagaagtc gatccagata aattagtctc acgtccgcca gtagtaacga
    12661 ttatgggaca cgtagaccac gggaaaacaa ccttattgga tacattgcgc cattcacgtg
    12721 taacaagcgg cgaagccggc ggaatcacac agcatatcgg tgcctaccag atcgatattg
    12781 atggtaaacc aatcactttc ttggatacac caggacatgc ggcctttaca agtatgcgtg
    12841 cacgtggagc aagtatcaca gatatcacga tcttagttgt tgctgcagat gatggcgtca
    12901 tgccacaaac agttgaagca atcaaccatg ccaaagctgc aggcgttcca atcatcgtcg
    12961 ctgtaaataa aattgataaa ccaggtgcaa atcctcagca tgttatgcaa gaattaagtg
    13021 agtatgaatt aattcctgaa gcatggggtg gagaaacgat ttttgttgag atctcagcga
    13081 aattcggcca aaacatcgaa gaattgctgg aaatgatcct gttagtcgca gaagtagaag
    13141 atttaaaagc agatccaaca caacgcgcaa tcggaacagt gatcgaagca cgtcttgata
    13201 aaggtaaagg tcctgtgtca accttacttg tccaagaagg aacacttcac gttggtgacc
    13261 caatcgttgt cggtaatact tacggacgtg tccgtgtaat gacaaacgat cttggccgtc
    13321 gcgataaaga agcaggacct gcaacgccag tagaaatcac tggcttgaat gatgtacctc
    13381 aagcaggtga ccgtttcgta gtcttcgaag acgaaaagac agcacgtgca gcgggtgaag
    13441 aacgcgcaaa acgtgcatta ttggaaaacc gtgctgccac aagccgtgtg actttggaca
    13501 acttatttga aagcctgaaa gaaggcgaat tgaaagaagt taacgtaatc atcaaagcag
    13561 atgtacaagg ttcagcagaa gcactggctg catcattgaa gaagattgat gtggaaggtg
    13621 tccgtgtaaa aatcgtccat tcagctgtcg gagcaatcaa tgaaagtgat gtaaccttag
    13681 cagcagccag caacgctatt atcatcggtt tcaacgttcg tcctacaccg caggcaaaag
    13741 tgcaagctga tactgaagaa gtcgatattc gtcttcaccg tatcatctat aaagccatcg
    13801 aagaaatcga aactgcgatg aaagggatgc tagaccctga atttgaagaa aaaatcaccg
    13861 gtcaaatgat cgttcgtgaa accttcaaag tttctaaagt tggtacgatt gcaggtgcct
    13921 atgtaacaga aggatatatt cgtagagata gcggtgtccg tgtaatccgt gacggaatcg
    13981 taatctatga aggccaactt gcaagtctga aacgattcaa agatgacgtg aaagaagtca
    14041 aaatgggtta tgaatgtggt gcgatgattg aaaaattcaa tgacatcaaa gtagatgacg
    14101 taattgaagg atttatcatg gaagaagtca aaaatgacta aaaactgata aaaggaggcc
    14161 aatcattatg gctaactacc gtgatcgccg agtcggtcaa gaaatcttaa aagaagtcaa
    14221 tgatattttg cgcaaaaagg tccgtgaccc tcgtgtggag aacgtaacga tcacagatgt
    14281 gaaagttacg ggggacttac agcaagcaac gatctattac agcattttat ctgacttagc
    14341 atcagataag aaaaaagcac aagatggatt gaataaagca tcaggattga ttcgtcgaga
    14401 gttagggcac aatctaagta tttataagac acctgaattg ttctttgaac ttgatgaatc
    14461 agttgtctat gggaaccata tcgatgaatt gcttcgcgac ttgaacaaag actaatcaaa
    14521 aaatcccgca aatcctgtga aatcaggggt tgcgggattt ttttgttttc attaagacgt
    14581 attacctaag agttccatga ctttagtctg gtagcgtgtc agctaaccaa aaaagagaaa
    14641 aagaaaagta aaaaattcga ctttcttttt tctatagtat ataaattttt gcatatagat
    14701 aaagatcaag ataccgataa cggaagctag attgtaatct attttagtga cagtcaggta
    14761 tagccaagta actagaagat cagtggaacc tgcaccataa aagtttgagt ttgtcggtcc
    14821 gttgacagtt aaaagaaaaa tcacgttgaa gttattgata tttccgatta cgccgcttcg
    14881 atttggtcac gatccaaatt ttggataatc cctgtagaaa ttagcatagt agctgggata
    14941 ccaattcaca tattgacaaa gataacagag acttttacat aaaacggatc aatcaggaaa
    15001 ggaattgctc gatccagccc cagttttcca acaatgtgtt aactggccta gcgtcattca
    15061 gcaaattatg catgatgagg agcgaaatga actgcggaac agccattgtg ataacgacaa
    15121 gttttttgga tcaatgtaaa aaacgtcagc gaaaggaaaa atttcgtggt tttttatacc
    15181 tgttcatttg gctagatata aaatccaaac aaatgaacag aagtgcttat taggtttcaa
    15241 ttgggagtat ctgcgctaga ataagagtaa taatgaaaag gagtgttatg tatggattat
    15301 tctagtaaag aatactttga taaaatgacg gcttggtggc gtgctgctaa ttatctttct
    15361 gttgggcaac tttatcttaa agataacccc ttactgagac gtacactgaa accagaagat
    15421 gtcaaaaaac atccaatcgg tcattgggga acgattcctg gccaaaattt tatttatgtc
    15481 catttgaacc gagtcatcaa taaatatgat ttgaacatgt tttatatcga agggccagga
    15541 cacggcggac aagtcatggt atcgaatgct tatttagatg gaagttacac agagatctat
    15601 ccagaagtaa cggaagatga gacaggaatg caaaaattat tcaagcgatt ttcatttcct
    15661 ggaggcattg cttctcatgc agcaccagaa acaccaggtt ctatccatga aggcggagag
    15721 cttggatact ctctttcaca tgcagtcgga gctgtattag acaatcctga agtaatctct
    15781 gctgtcgtga ttggtgatgg tgaagcagaa accggtcctt tagctggaag ctggttctca
    15841 aatgtcttta tcaatccagt gatagatgga gctgttttac cgatccttca tttaaatggt
    15901 gcaaaaatag ccaacccaac gatcttggca cgtaaatcag atggagaatt agcaaattac
    15961 tttaacggac ttggctggga gcctttcttt attgaaggaa atgatccaga aaaattaaat
    16021 cctgttatgg ctgaaaaaat ggatcaagca atcgagaaaa tcaaatccat ccaaaaagaa
    16081 gctcgcctga agacagcaac agatgtcgtg atgccaaaat ggccagtatt gatcgtacgc
    16141 acaccaaaag gatggaccgg tccaaaagaa tgggacgggg aaccaattga aggaaccttc
    16201 cgagcacacc aagtaccgat tcctgtagat caagaacata tggatcatgc agatgcttta
    16261 ctccgttggc tgaaatccta tgaaccagaa aaattatttg atgcacaagg acgtatttta
    16321 gaagaaatca gagaaattgc gcctactggt gaccaaagaa tggcaaaaaa tcctatcacc
    16381 aatggtggaa tcgatccaag accgcttatt atgccagatt ggaaaaaata tactttgcaa
    16441 tttgaaaaac taggctccgt taaagcagaa gatatgaccg aacttggtaa attcgttcgc
    16501 gagatcattg agaaaaatcc agaaaatttc cgtatatttg gaccagatga aacaaaatca
    16561 aaccgattga atcaagtttt caaaacgaca aatcgccaat ggatggaaaa aatcgaacca
    16621 gaaaatgatg aatggctttc gccatctggt cgcgtcatcg acagtcaatt atcggaacac
    16681 caagatgaag ggttcttaga agggtacgtt ctgactggac ggcatggttt ttttgcaagt
    16741 tacgaatcat tcttgcgagt ggttgactct atgttgactc agcacttcaa atggatacgg
    16801 aaatcacatg acctttcttg gcgaaatgat tatccttcgc taaatctcat tgcaagctca
    16861 acagtcttcc agcaagatca caatggatat agccaccaag atccaggaat attgacacat
    16921 ttggcagaaa agaaggcgga gttcatccgt gaatatctgc ctgcggatgc aaatacattg
    16981 ctcgcagtca tggataaagc attccactcg tcagaaaaaa tcaatttgat catctcttcc
    17041 aaacatccgc gtgctcaatt ttactcagca gaagaagcag ccgtcttagt gaatgaaggc
    17101 ttgaaaatca ttgattgggc ttcgacagca aaagaggagg aacctgaatt ggtcattgct
    17161 gctgcaggaa cggaatctaa cttagaagca ttagcagctg caactttgct gctggaagaa
    17221 ttcccaaaac taaaaattcg gttcattaat gtcgtagatt tattgaaatt acgtcatcca
    17281 agtcaagatc cgcgtgggtt gagcgatgaa gaatttgatc aatattttac aaaagacaaa
    17341 ccgatcttat ttgctttcca cggttatgaa acattggtcc gcacgatttt ctttgatcgt
    17401 cataaccatc atttaatgat tcatggctac aaagaaaatg gagatatcac gacaccattt
    17461 gacatgcgtg tagtaaatga acttgatcgt tatcatttgg caaaagacgc agctttaaaa
    17521 atcaaaggaa gtcaagcaga agattttgcg gaaaaaatgg atcagaaatt acaagaacat
    17581 caaaactata ttcgtgaaaa tggtattgat ctgccagaag tattggattg gaaatggaaa
    17641 aatcttgatc aataaaatga taaaatcgat cccgcaaaac agaatttttt acattgatta
    17701 agaaactgaa aaaataaata aaaaaaacgg aaaaaagact ggaagaatgg acagtctttt
    17761 ttttcgtttt tgggaagtga aaaccaaact atttacctgt aagccaccca taaatccaat
    17821 caaatggtgc aaagaaaaaa tcttccattc tattccctcc tttaaaaaaa cataacatga
    17881 tttctattta cgtgagcatg aattttgtta cgtttttatt gccgaaaaat aaaaaccgtt
    17941 cattatgatg tcaaattcgt cagtaattga tgcaatgtgt tataataatt cagttaaatc
    18001 aaaaatgaaa tggagaaaag acatggacgg gttattacct ttatggaaag aacgcggaat
    18061 gacaagtcat gattgcgtat tcaaattaag aaaaatctta catacgaaaa aaatcggaca
    18121 tgggggtacg cttgacccag acgtagacgg tgtgttgcct atttgtattg gaaaagccac
    18181 aaaagttatc gagtatttga cagattctgg gaaaatctat gtaggcgaga taactctagg
    18241 tttcagtaca acgacggaag atcgatccgg agaacgggta gaaacaaaac cagtagatat
    18301 gtctttatct gaagaaaaaa tagatgaagt gatggcttca tttattggtg agatcaccca
    18361 gataccacca atgtactcag cggtaaaagt caacggtaag cggttatatg aatatgcccg
    18421 caataatgaa acagtggagc gtcctgttag aaaggctcag atttaccgtt ttatccggac
    18481 aagtgaattg acaagagacg aagtgacagg aaccatttct tggcgcttcg aagtagaatg
    18541 cgggaaagga acctatgtcc gcacattagc tgtagataca ggcaagaaac ttggttaccc
    18601 tgcgcacatg tctgatctga cccgaacagc aagtgccggt atgtcccaga aagatgctct
    18661 gacattagaa gaagtagctc aagctgtgaa aaatgggaca atcgatgatt gtttgctgcc
    18721 aatagaaaaa ggagtgaaac gattcaaacg agtagatatt actgatgaag tatggcagaa
    18781 agtaaaaaac ggtatgagac ttgattatac tgtatttgcg ctcccagaaa tgccgtcaga
    18841 agaaattgct ttgttttata aaggcaaagt tgtcagtatc tatcagccaa acccgaaaga
    18901 aaaaaacaaa ttaaaaccta gtaaagtatt gagaaatgag gaataacgaa tgaatatcat
    18961 caagatcaga catccttacc aatcagaaca aattccagaa gacgatgtcg ttttagtact
    19021 gggatttttt gacggcgtgc atattggaca ccagaaagtc ataaagacag gtatggaaat
    19081 tgcacaaaaa gaaggattga aattagcatt gatgactttc aatcagcatc catcgattgt
    19141 ctttaaaaag atcgatccta gcagcgtgaa atatttgact agccttaagc aaaaagaaga
    19201 aaaaatggcc gctttgggta tagattattt atatgaagtt gattttactt cttcttttgc
    19261 tcatttagca ccgcaggaat ttgttgatca atacatcgta gggttacatg caaaatatgc
    19321 tgtttccggt tttgattata cgtatggacc aaaagacatt gcagatgtcg ctcattttcc
    19381 tgaatatgcc aaaggaagat tcaaaatcgt cacagtttct aaagaagaag aacaaggtga
    19441 aaaaatcagc tctacccgta ttcgaggatt actagacagc ggacaagtaa aagaagcagc
    19501 aaaactatta ggttgcacat atgaggtaga aggggtagtt gtccatggcg atgcacgagg
    19561 cagactacta ggattcccta cagcaaatgt caaagtaaag agcacagttc atttgcctaa
    19621 agaaggtgtt tatgtatcgg aaataaaaat tggggaaact tggtatccag ccatgggttc
    19681 aattggacat aatgatacat tcggtgaagg acgggagctg actgtagaat tgtatatttt
    19741 ggactttaat caagatatct atggtgaaca tgtcgcagta cgctggaatc aatttttaag
    19801 agatcaagtg aaattttcta gtgtagagga attgattgaa caactcaaaa aggatgaaca
    19861 agcaacagct gaatattttt ctcagcaata aaacattatg cataaaatct cttgtttatg
    19921 tataactagc aatttcaata aaatgggtga taaataagcc caggaaaggg gctgtgacaa
    19981 aagtcttgtc acagcc
//
LOCUS       DAPBCF010000049        19423 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.050, whole genome shotgun sequence.
ACCESSION   DAPBCF010000049 DAPBCF010000000
VERSION     DAPBCF010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.050"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            283..522
                     /locus_tag="RD508_002144"
     CDS             283..522
                     /locus_tag="RD508_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736694.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="RD508_002145"
     CDS             complement(884..1144)
                     /locus_tag="RD508_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736695.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="RD508_002146"
     CDS             complement(1329..1826)
                     /locus_tag="RD508_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HDT7736696.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1956..2666)
                     /gene="budA"
                     /locus_tag="RD508_002147"
     CDS             complement(1956..2666)
                     /gene="budA"
                     /locus_tag="RD508_002147"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HDT7736697.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="RD508_002148"
     CDS             complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="RD508_002148"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HDT7736698.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4548..5210)
                     /locus_tag="RD508_002149"
     CDS             complement(4548..5210)
                     /locus_tag="RD508_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7736699.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5220..6035)
                     /locus_tag="RD508_002150"
     CDS             complement(5220..6035)
                     /locus_tag="RD508_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7736700.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6297..6740)
                     /locus_tag="RD508_002151"
     CDS             complement(6297..6740)
                     /locus_tag="RD508_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HDT7736701.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(6874..7212)
                     /locus_tag="RD508_002152"
     CDS             complement(6874..7212)
                     /locus_tag="RD508_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7736702.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7200..7577)
                     /locus_tag="RD508_002153"
     CDS             complement(7200..7577)
                     /locus_tag="RD508_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7736703.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            7801..8994
                     /locus_tag="RD508_002154"
     CDS             7801..8994
                     /locus_tag="RD508_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7736704.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9160..9582)
                     /locus_tag="RD508_002155"
     CDS             complement(9160..9582)
                     /locus_tag="RD508_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7736705.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            10172..10627
                     /locus_tag="RD508_002156"
     CDS             10172..10627
                     /locus_tag="RD508_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736706.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            complement(10789..11961)
                     /locus_tag="RD508_002157"
     CDS             complement(10789..11961)
                     /locus_tag="RD508_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7736707.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12167..13596)
                     /locus_tag="RD508_002158"
                     /pseudo
     CDS             complement(12167..13596)
                     /locus_tag="RD508_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            complement(13593..15095)
                     /locus_tag="RD508_002159"
                     /pseudo
     CDS             complement(13593..15095)
                     /locus_tag="RD508_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345213.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            complement(15092..17419)
                     /locus_tag="RD508_002160"
     CDS             complement(15092..17419)
                     /locus_tag="RD508_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7736708.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            complement(18262..18555)
                     /locus_tag="RD508_002161"
     CDS             complement(18262..18555)
                     /locus_tag="RD508_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HDT7736709.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            19057..19287
                     /locus_tag="RD508_002162"
     CDS             19057..19287
                     /locus_tag="RD508_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736710.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
BASE COUNT         5693 a         3778 c         3321 g         6631 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatgatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat taaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg gatttctgct
     1981 gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc
     2041 tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc aaaatccatt
     2101 acatgtccgc caaatgtatg tgtatcatcg ataaaatgca agtgaaatcc cgctgcagca
     2161 actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggac attgctttgt
     2221 tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc
     2281 ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc caaaaatagg
     2341 ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc tgcagttttt
     2401 gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca
     2461 cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac gccatctaaa
     2521 aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc tttttctaat
     2581 atatgagcaa tcgtttctgt tccatccatc aagccagcca tcaaagctcc taatgtcccg
     2641 tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg atctggtaag
     2701 attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat aattacgggt
     2761 ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact tgtagctcgg
     2821 attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc aaagtctaca
     2881 cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta gtgtccatca
     2941 ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa atcctgggca
     3001 gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg acgcaccaat
     3061 gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt actgaataac
     3121 aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg actacctaca
     3181 tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat aacttctaaa
     3241 ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt taattctgct
     3301 tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc taatgaacct
     3361 gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg ctgcataaaa
     3421 ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc
     3481 cagtttcttg cttcatattc gattggatca tagccaatag caataactag atcacttcgt
     3541 ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa gaaatgcgct
     3601 tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg caatgctgtc
     3661 tttccaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg catacctact
     3721 aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat atcatctgca
     3781 gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattcccttg gacaggtgca
     3841 tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact cttagccata
     3901 cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc tgcactgtat
     3961 tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa cttcaataga
     4021 tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc tgtcgctgtt
     4081 accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac tactcctggc
     4141 tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc
     4201 acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat ttttgcacct
     4261 ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac agatttcgaa
     4321 ccttgtttca ttttttcgtc cattgaacat cgtccttttt atgctttatt tttaattatt
     4381 agttagaaat aatcacaaat aattgataca gtttctaaac ctgtttcatt caaaagtata
     4441 gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga atgacagttt
     4501 ttacataaaa actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata
     4561 gttctcatca atttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt
     4621 agaatacacc attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa
     4681 tctagtaaac tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga
     4741 tttggtttcg acgctggatt tctcacctga aaataccagt agttgatgct aaaggaaact
     4801 gataaacaag caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata
     4861 aaaaagaaac aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa
     4921 aatcccttta gccaaaattg gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt
     4981 ttttcttttg ctaattcttc tgtcatacct atcatcacga tgcaacctgg accaataaaa
     5041 agtaaagaaa aaataaagga aaagacattc cttccatcta tcgacaaaag gaacgcagct
     5101 gctatataca agatattgac acaccaaaaa caaaggctac ttgccaatga ttgatacaac
     5161 caataaaaga attccatata aacatttttg tcaaaacgct gctctttcat aatcacctcc
     5221 tattccttca ttcctgatga agcgatccct tctacaaaat atttttgcat cgctaaaaat
     5281 ataaaagcaa caggaagaac agaaacaact gaggcagcca tgattaatgc gtactctgca
     5341 tcaaatagcc caataaacat tttcaaccct aactggattg ttttattttc cgtagaagac
     5401 aaataaatga atggccccat ataatcgttc catgtattaa cgaatgtgat gatcgtcaaa
     5461 ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc gatagattcc ccactctgat
     5521 aagccatcga tccgcgcact ctcacataaa gaatctggga tactactgta gtattgcttc
     5581 aacaagaaca caccaaaagc attgaacgct tgtaatagca ccaacgacca caacgtatat
     5641 gttaaaccca cttttctcat cataatgaac tgcgggatca tataagactg ccaagggaca
     5701 gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc ctttaaaatt tagtttagaa
     5761 aacccgtaag cagcaaaact agaagtaaac aactgaatca acgtgatcac aacgcttaaa
     5821 aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag accaaataac cagataattc
     5881 tctaaatgcc aagttttagg gatccattga atcggaatcg tgaacacttc attatttgct
     5941 ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg tcaataaagc taatacaatc
     6001 agcagaatca tacccaacca ttgaataaag ggcatgtttt ttgaacgaat ttttgctttt
     6061 tttctttcat ttcgaacacc tccaaagtta taatcttcat ttctttgtaa tgattacaat
     6121 ccagaacaac ggttattata gctgattcat ttccgttctt cttatgtttg taagcgctta
     6181 tttaacaagt tatgtaaatc tctttatttt ttttgattta aaaatgaaaa aatacaaaag
     6241 caagactgtc atacgtctcg cttttgtatt gaaatttctt cgattagaga tacttattac
     6301 tgttcaaaag cttctttgaa acggtgaatc aattcattga ctacaggtga taaaatccga
     6361 ttctttttcc agactagcat gcagttcgtt tcaatcattg ggtcaagcgg aacgaatgtc
     6421 actcgctttg aaagatgact tacagcacct tctatgacta aagcagcacc tacctgattc
     6481 tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc ctgtgatcag caactgctcc
     6541 ttttttatgc ctaaccagtc agcaaacatt cgctgtattt ctggacgctt tgagatcaaa
     6601 agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt tttttgctaa aacagaattt
     6661 tctaaaatga gcaatcccca tttttccttt cttggtaaca aaatcgtttc gtatttctct
     6721 gtatctactg gatctagcaa aatcgctaaa tctaacaggc ttttttctag tcactccgtg
     6781 atatcatcac ttgttccgct gtggatatga aattgaacgc tgggataatc acggatcaac
     6841 ttttctagta atagtgccaa tgtattcgaa ttatcagctt ccacacagcc gatcgtaaat
     6901 cggccgctga ataattgttt ttttctgttc tcgaattctt gagtggtttg attcgttaaa
     6961 tctaaaattt cttctgctcg gcttttttag aaaataacct gcttctgtca agatcatttt
     7021 gcggttttcg cgtacaaaca gttctgttcc tagttcctct tctaactcct tcagttgtcg
     7081 gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct tgagagattg ttccttcttc
     7141 tgcaattgtc caaaaatatt ttagtaagcg taactccata gcgatgctcc ttgatttttt
     7201 tacttgatac attccatttt atttctagat aacacacgat catatttctt gatttttcct
     7261 tgtaaacgtt ccaaacattc ttgcatttca gcaatttttt tcgtcaaaag ttcactttct
     7321 tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc cttcgctaga taggcgaata
     7381 tattcaatca aagactcgat cgataatccg gcatttcgca tacagatcgt aaagtcgacc
     7441 cattttaggt cttcttctgt ataatcacgg attccgcctt ttgtccgatt aactggtgga
     7501 atcaacccga ttcgttcata atagcgcaat gtatcggccg aaatgccctt ttcttcactg
     7561 acttgtttga tattcatctg atcactcttt ctcttaattt cttgccactt tacttatgta
     7621 ttttatttat tctacaactt taagtgtact ccaagtcaat actcatttct attaaaacta
     7681 agctggatta tctatatcgg ttgtttgtgt attatttcaa ataaaaaagt cttgtttttt
     7741 tattcttttt tggatatact tttaacaatt tagggaaatt ttaggaaaag gggtataaaa
     7801 atgacaacgt atcagcgaaa gttattatta tcgacatcgg cgggaattgc tttagagaat
     7861 atggatatta tgtttttagc tttttcatta tcttcaatga ttacttcttt tcatattagt
     7921 ggtacgcaag cgggtttcat ttcaacgatc actaatttgg ggatgctcat tggaggtatt
     7981 ttttttggca tcatagctga taaatatgga cgtgtgaaag tattttctca aacggtcctt
     8041 ctgttttcga ttgcttcttt attgatgtat tttgcttcaa acatctactt ggtttatctc
     8101 tttcgcttta tcgcaggtgt aggagcggga ggagaatacg gggcgtgtat gtccttgatt
     8161 tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt cggttgctgg tattggtgcg
     8221 caggtcggtg cggctttggc tgcgatttta gctgctgtga tcattccaac gtttggttgg
     8281 aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg tcttgttcat tcgtcgcggc
     8341 ttgactgaac caaaggaatt caaatctgta caatctgccg aaaagaaaac caaacttagc
     8401 agactgtttg aatcaaaaca tcttgcttgg caaacatgtg gccttagtat catggtaact
     8461 gtccaaattg ccggctattt tgggttaatg aattggctgc cttcaattat gcaaaatcga
     8521 ttagggcttt cggtttctgg gtcttcattg tggatggtca gtactatttt aggcatgtct
     8581 ttggggatga tgacttttgg cataatcatg gataaattgg ggcctaaact agccttttct
     8641 ttgtttttaa tttgttcatc cttatctgtc tatctacttg tgttagccca tagccagtgg
     8701 agtttggtag cagccgctgt gatagtcggc tactttatca atggcatgta tggtggatat
     8761 ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg cgacggcgaa taatttcatt
     8821 atgaaccttg gacgagctgt tggtggtttt tcttctatcg tcatcggttt cttgatggat
     8881 cattatagtt taactgccgt aatcttgttt ttgagcggta tttacctagt cagtctgctg
     8941 gtcttgacaa ctcttactgg tgttacagca ttaagggaaa gcttgcagca ttgatagttg
     9001 agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc atctgcggta ataagaccag
     9061 ccaaatcaaa aacatgagac actgtttccg tttggctggt cgtattactt gatgcagggc
     9121 agctttttca actgctaatt tccttctatc tggcggctac tattctttga cgtccgtcat
     9181 ttcaaagtac tttactaata acttagcata acgaaaaact gtggatacac tcgtatattg
     9241 agcgtctgca taatcttcca aatttttctc aggatgttga tacatgaatt caatcaaatg
     9301 ataattatat gattttctgt agaaatgaag ataaataatg tagattggga agttctcctg
     9361 cttttccata gaaaagcgcc gattattctc attcttcaaa atgaccttat caggatattt
     9421 ttggaacaat tcttctaaat ctgttagata attcaagata gacttacttg ataccttcaa
     9481 ttcgttttgt agttcttcta ttgaacacca acgttctgtt tcaagcagta aatgaatcat
     9541 tttaattttc ttttgagaaa cttttgttaa aaaagtctgc atattttctc ctcctgtatc
     9601 tactttacta tactacatac aagaaaaaaa acggatacaa atatcatatt gtcacaccgt
     9661 caatagtgca taaacctgtt attatttctc tttttttcct aagtattcta ttgatatgaa
     9721 tcatttaatc gtttattata taaatgtcaa taatctaata ataaaataac gtacatattt
     9781 tattattgca tacttaataa cagaactata gcaaaaaatc ccgtgtatca aaacgggatt
     9841 agattaagtt tcctcaatca ctattcataa cacaattatt ataacaagta agtaaacaat
     9901 tgaaaaggac atttattgaa aacggttgtt ttttacttaa ggaggaaatt tagtgaaaaa
     9961 attagttgca ttgtttttgg tcgcaggaag tttgttgagt gggtgtggtg ctactacgtc
    10021 tactactcaa agcacaagtt cagctcaggc ttccagcagc agtaccacga tctccgaaag
    10081 tacggcagat tcatcgaaag aacaagaaca aattgaaaag aaaaaagaag aagagaaaca
    10141 aaaagcggaa aaagctgcac tagaaaaaaa agtgacagaa gcggaatctg ctttgtcaca
    10201 agctgaagca aatcctacaa aagaaaacta tgcaactgct tcagcagcta tccaagcgct
    10261 acctgaaaac aaacaagagt tgacaagccg tcttgctgca attgattcca caatcaaagc
    10321 aaaagaagca gaagaagaac ggaaaaagca agaagaaatt gcacgacaac aagcagaaca
    10381 agcgcaacaa gaagcaatcg cacagcaaca agcagaacag gcgcgacagc aagcagcagc
    10441 tgaacaggcc tctcagcagg cacaagccgc agctcctgag caaaataatg aacaaactgt
    10501 ctatgtcaca ccgaccggtt caaaatacca tacacataaa tgtggaaatg gtacgtatac
    10561 ccctgccact ttaagcgaag ctcaagctcg tggtttaacc ccttgctcca aatgttatgg
    10621 aaactaattc aaaagttata ctataataat aaaattcttc tgaaacataa aaaaatagaa
    10681 gctggcgttc cagatagtaa accaaaaata gcagtttaca cgtccatttc gtcagcttct
    10741 ctcttttttc atttagtctg ttccctctgc ttttttggac atcttcattc attctttctc
    10801 aatcaaatag tacacctctt tttcttttcg cagtttatat cttccttttt tcaatttcat
    10861 tgaaaactgt ttcgaatgtt tatgttttac atggatttta agcaggagct cctcatgttg
    10921 caagcgatag ttcctgcctt ttaaatcaga aaatctcact agtccgtatt catcagaagc
    10981 tttcacaaat ggaacttttt ctctagtaat atagtgtttg ccgttgagcg tttttacaga
    11041 aaagaccatt ccttcgattg gtcgtccgtt tgtgttcttt acataaaaag ataaaggata
    11101 gtttcgctta gcgatggcca aagaatctaa ataagcgatg agtagccaaa ctaagccgat
    11161 tgatccaagt agtataccga taaaccaaat aaaaaatttc cattttttcc attgatcaat
    11221 tccttggatc gctttttttg cctcttttgc ttgataagga atacgatgcc ccgtcacaag
    11281 cagtcgatgt gtattgacca tataaggagt acaggtaagc aaagtcacga gatctctgcc
    11341 tttttggata cccaaagaat ctacttcatc aggtaagacc acttggattt tttctacttg
    11401 atacgccaat gtctttccat tgatctggat gaaaaactgg tctccttttt tcaacttagg
    11461 caaatctgta aataattttg cttctgggag tccacgatgc ccagaaagaa cggcatgggt
    11521 gtttttcccg ccagtcggat aagaactttc ttccaataat gacgttcctt tttgcaaaaa
    11581 tatttccgtt gtctgatcga atataggtaa gctgacattg atttttggga tttcgatgac
    11641 tccaagcata tgttccataa aaaaggcatt actaggtaaa tcttttaatg cttttgcatc
    11701 aactgcttgg ttgaaactgc ctatccctgg tgatacgttt tgctctgcca actgttggtt
    11761 tttctttgtc attttttcct gctgtttttt tatttcctct gaattcttat tcgatgcttg
    11821 cttttgataa tggatgatca tttgctgggc aagaaaatca ttcagtgaat cttctacaaa
    11881 aggataagaa aagatcccga tcccaacgac taaaatgatt gccatgaaga tgtccagtat
    11941 tcttattctg cttttattca tcatgtccac ctattttcta atatgtatat gaagaggttg
    12001 tgaaatcagc gccttgacct gagtattcgc tcaacaaacg gcaaaatagt tcctcctatt
    12061 ttgccgtttg ttgagcgaat accaagagac cgaccacttg tcacaacctt tctccccatt
    12121 tgaatcacta tcgtttattt atcgtatgat ttttgtttcc aatagtttaa gcttctgttt
    12181 cttgatggcg ttttttgaag tagatcactg ctcctccaac taaagcagta cctaccaaga
    12241 tgaatacgat gatccccata ccaccagttg aaggcaagat tcctttaggt tggttatcga
    12301 tcgttgtttc atcagaagtt gttggatcat catctactgt aaattcagtg tacgcagctt
    12361 cattcttagg taatgcgtag ccttctggtg cttttgtttc ttgaaggcag tatgcccctt
    12421 gtttcagccc ttcgattgaa aatttccctt ctgaatcaga aatcaatttc acttcttccc
    12481 agtcagaacc tgtgacttca tctgaccaag catatgggta ttctcctgag gcaagatttg
    12541 ctattttttt cattaattta acagttggat cttttgctct tagaatagaa aattctgcat
    12601 cggctaattt ttcttgcgtg ttcacatctt gtttgatgaa gtggaaatca ccgtagtttt
    12661 ggacattttc tacagtaatc gtgttatccg tagttgtatt ttcccgattg actacaccgt
    12721 ttggattccc aagattggct tcatctgcgc catggatgat accggttgtt tgttgcaatt
    12781 ttccgttttt tactataaaa gtagtttctt tttgtggatt ggttaattga taaccatctg
    12841 gtgcttttgt ttcaactaaa gtataattgc cgtctattaa tccattgaca ctgatggatc
    12901 cttcagtatc agttgtgaat gtcaacgctg actcagcagg atcatagaga gcgacaccag
    12961 tgttttcatc aaaaccggtc acgaattgat tctctgaatt tttgatctgg aattgcgccc
    13021 ctgctaactt atctacccct gaaaagttcc cagctttctg gattttgata ttgctttctt
    13081 tgatgacatt tttagcatat aggtgaatcg tgtctaaagg tttgtcaggg tctgatgaat
    13141 tcgggttata aaagggtaag cttaacacga tatttggcga cgtttcgaca ccgggctttg
    13201 gtgtttctac aaagacgtat acagcatctt tcccatcaga tttacctgga agagtcaggt
    13261 tagctaatcc ttcaccagaa gtcgttacac ttgcgaaggg tgtagcgtct gctggaactg
    13321 ctgtgtcttt acttggatag tacgtagcag tgatgtcata tacgttgaat tcaacgccgt
    13381 tcaacggttc gctattcgga aatgtcaatt ccgttccgtt gtttatttga ttttctggtg
    13441 ctgaagtgaa tttcaattta tgcaaattaa ccgtaacatt ttctggtgta ggtgatacgg
    13501 cctagaaacc tctgcagttc ctaggccgag aacgaaagga agcagcatga tagcagttcc
    13561 taaaaacgtc catatttttg ttttgatgtt tttcatttta tttccctcct attgtttcct
    13621 ttttgttgtt ttttataaaa ccaagctgtc cctgttgaaa ggactagcaa caaccctaaa
    13681 attgagaaac ctccaagcat ctcttcgctt gtttttggaa agcttcctcc atttttttca
    13741 tttgatggac catttgtctg catctgaact ggcgtttttc cattattcgt cggatttgct
    13801 tttggttcgt tgatgatttc caatggtata ggatgaagcg gatcataact gcctttttca
    13861 acttcaaaga gaatggttga ttgactcaat atatatcctt taggcggttt aatctccact
    13921 agttcgtaac ttccaaaaga caatccatgg acagaaaatg ttccatcttt actggaagta
    13981 aaaatcgttg ctcttgaatc atctttggct acccaatgat ttatcccgtt ttcttgcgct
    14041 aagtattggt catttttttt gactagaaat tgagcatctg ctagtttttg tttcgtttgc
    14101 cgatccactt tgacaaattg tttgcctcct gtttggatgg caagatgtgt ttctactgtt
    14161 tgattgtcag tcgtcaaacg tacatcgtta tcaaatgtcg ttttttcact gttttctttc
    14221 aatgtcattt ggtaacggat cgttaatttt ttcccagcaa acgaactaag atcttttcca
    14281 gaatctgata agacaaaacc atgttttgtt ttttgtgtgt gaaatgtatg aatcttgtct
    14341 ccaccaatca aaaaatcgat cgtttctggt tctagccata actgaggatc agctgtatct
    14401 ttgatcgtat aggttcctat ctcgttgatg ttctcaggaa ttgttacggt gatgagataa
    14461 ggaactttat ccccatctgc aaaatctgtc tgcttattct ctactgtttt tgttaatgtg
    14521 agtgcagcag gtattttttg ttcgctcttt ggatacaagt ggatggtcgt caatttatga
    14581 ttagatgaat ctgtcacagg aagcacaacg acaaatggtg ctgatttttc ttttacttaa
    14641 tctgaagtct ttatttccgc aaatcggtaa acagcgtcac gaccttgctc atctttgtcc
    14701 gatgcactaa aagaagcaat gccctcttcc tcgtctactg tttttgtcac attttctgcc
    14761 agtatttttt cactatcact tttttgtgct agttttcttt gtgcgtcttc cacactactt
    14821 ccttctgacc gcagcttgta aaattcatcc gagacatcat atatagcgaa agtaacgccg
    14881 ttcaaccctt ttactccttg aaagttatcc gggatattta ttccgtcgtt ttgactgata
    14941 cttggcatct tatcgctttc gaacattcga ttatgcaaag taaatgtaat aggtgattct
    15001 ctagctgaca cagtcggaga acctataaaa aagaccagta ggataaaaaa gagaacagca
    15061 aatatatcca cacgtacatt ttttgttttt ttcatcgctg ttcacctgct tttttcttac
    15121 gatggataaa ataaaagaag ccagaaaaaa taaagatcag tcctaaaaag acaaagggca
    15181 gtagacctat cccacctgtc gaaggaagca agagagtcgg attgatcgtc aacttagcgg
    15241 tatctgttgc gataatcgta taattattgt ttacacttcc ttcgcctaaa ctaatcgtta
    15301 ctatttgtga tccaatatct gtccggctgt taactgttag ggtataatcc aatgattcgc
    15361 ctaagacaac accggtaacg tggagatttc caaccgaaat cgagtgactt tgggcatcat
    15421 aattaaaggc agcgtcatcg acagtaatca ctgcgttagc tttatagatg gtataagttc
    15481 ctgatgtgtt ggctatatca gtaaatgaca acttgggatt tgctgctttg actttgtcta
    15541 ttccgctatt cgttagttta attgtatagc tgccagcatt aaccatattt tttgctgatt
    15601 gtgcatctgc tgtgtaatcc atactgctaa gtgccacttg tactggagta agcgaactag
    15661 tgacaccctc tgctagcttg acatggattg acgggacacc tgcttttcca tcatatgtct
    15721 tactgccact gagctctacc gcaccgctga tttgcttaat cgtatagaca tcagatgtct
    15781 gcacgatagt aaataaatag tttgttctgg cagctagttt agctagtccg ctttttgtca
    15841 attgccaaga cgtataggtt ccaatttcag taggcgcagt tacttcaact cccttttcat
    15901 tcatcgcttt gaaatcagtt ggattccatg tgatttgatc aatactgaga tcattgttta
    15961 aaagggatgt tgattctgtt ttatcattaa aggcatattt aacgatcggt acaacagaaa
    16021 gaccatcata gtacttactg ccatttgcat tgattgatac tgttgcattt gtcttataat
    16081 ataggatgac ttcagaaatc tgttttccat ttgcgtcctt tacgattaca tttccatttg
    16141 tatctaaact agctaaaaca ctcattgctg attggttctt tgtttctgtc gctgaaacag
    16201 ctgtaaaggt atatccgttg atagtaggcg tattagtcgt caggtcttgt gcagcacttc
    16261 cgtaagtaag attcattatt ttagaaggag caatcatctg tccaaaatag tcttgatact
    16321 taatagtgat tggtgtttgt ttgcctgtat aggtcaccgt atcgacgtta ctttctaggg
    16381 ctgtgaaaga accgtttgtt tgtgcaaaag aatagcccgt tactgctgtt ggagtgataa
    16441 ccactttgtc acccacatgg attccagata atgtagtccc gtacgttccg atttttgctg
    16501 ctccaccatt gactgtataa gaaaaagttc ctgtccgatt cgcattgacc tgaaccgttg
    16561 ctgcttgata ggttggaaaa tttgaaacat ttcccttacc atcaacgatc tgcccatttt
    16621 tgatcgagta ccccgtgaat ggaatatcat ttgctaactg tataccgatt gaaaaagtac
    16681 tcatacctcc tccggcagga agccctcccc atgttgaggg tgtaaaagaa taacttttat
    16741 ccgcattggg tgtaactgaa tcgatcgtat ttccagcggt agccaccccc atatagatac
    16801 tttttgggaa tgtgatagta gtaccattta ctgtggagcc aataaacaga ttatggatat
    16861 ctggacggtt atcaataaaa gcgattgctt tggttacgcc ttgtaacgca gttttatccg
    16921 cactcatcga tccgttaacc gcaacaatga ctccatcttt ggcatatatc actgtatatc
    16981 catctggtat ggtatgtccg ttgaaattcg cagtggccgc aacagtacta aatgtctggc
    17041 ttctacctgt ttctgaataa gctttctccc ctgctgcttt tgctgctgtg atttcttttt
    17101 ctgtcggatc aatcagttga gtcgaggatg tggttgaggt tgtctcgttg ttgctagact
    17161 gattggtgct ttctatggac tgtatttcag aatagggtgg actatttgtc tcctctgtcg
    17221 tttggttagc aaaatttgac gtttctgtat aaacgtttac ataaatactt gataagctcc
    17281 ctaagaaagt aaaaatcaag atgatcgaaa tcataatggg atgtaagtat tttcttttag
    17341 atacagcttt gagtctagaa acaaaatgtt tttgacatat acgttggatt ttattttgag
    17401 ttttcttaat cattttcatc cctcctctca ataaaaaatc atcaaataat cctttacacg
    17461 ttattctaaa tttaattttt attattttat tgatgtatag aaagtttggg gctttttttc
    17521 tctttttatt ctaaggttat tttagtcttg tcctttaata caaagatttt atttttaaat
    17581 aaaaaatact ctttttttac gattattgaa aaaaaaagat aaaacttgat taattgaagt
    17641 attgcttaaa tttggaagct atgagggaag aataaaagag ttaggacggg attatctact
    17701 atttttcttt gttttaaata tttgttatct ttgaacataa aagagaaatg tgtcgactgc
    17761 agtgttgtgt ccctcatcac gaataaacgg tgttcaatta gctgatcttg tattcactta
    17821 aaaaatggta aagtacgagt tgctattccc cattttcaat tttctaacgc tcaggacaaa
    17881 atactgtttt cacaacctca ttggaataaa agcatatata ttgtttcaag aacgaaatct
    17941 tgttatcttt ttaaagggca tctgtccaaa atctaatttt aggaggtacg ttttggtatt
    18001 tattcgtaca aataaaagag aattatcttt attcatgtaa cgcatccaat tgattttttc
    18061 atgtacgctc ctggaacgat tttactgacg attgcttatt taactgcgaa tcgctcatta
    18121 gcttttatca tagctatcca tattttgaat aacgttcttg gctttgtatt atagatacag
    18181 atgacaaaaa aagttcaagt atgcggtgta gaaccaatat cgcatacttg aacttttttc
    18241 aatgagtata aattaaaact tctaattttc aattcccatc atctgatatg cccgaccgtc
    18301 tgaacttctt ttgaaaaagc caaatgtgat tagataacgt ctttgttcga cataatcgcc
    18361 actagaaaat acgttcagca gtatcgaatt aacctctgtt tctgtataag tcactccatg
    18421 gtcaaagcgt ttcaagactt ctttcaatag gatgtatttc ttttttgttg aacttggtac
    18481 ttgttttact tttccatcat tcatgaatgt gtctaaaact ttcatctttt cttgctccgt
    18541 ataagtataa accatcttct ttctcctttt gattctaaga atactccatt tatgttagaa
    18601 tattctggat tttttattaa agcggttact cttaagaaag atattatcat agtgctcttt
    18661 tttttactac tacttatagg tagatttatt ctaatccatt attctcccct accaataatt
    18721 aaagaaaaaa ctggatcagg gtgttcaaat tacatgctaa gaaaaaagaa cccttgaata
    18781 ccaagggttc tttctcagtc tgataacaat gattaacgac ggatttcttt gatacgagca
    18841 gcttttccgt gtaatgcacg taaacaaaac cactatattc tattatgtat ctaacaccct
    18901 caaaacagct ataaatcaac aataccgaca taaaataaac actatgttca atctgagata
    18961 tatcaaaggt aaacgcattt ttgccccctt tttgcccctc aaatatcgct ttacaacaag
    19021 aacgtaagtt cgtataatcg ttttgaggtg atttttatga tggaagaatt tattagaaaa
    19081 aatatcagtg atgaatatgc agacttttat gatcaaagca gtaaaaaaga taaattccag
    19141 atggatgttt caatcttagc tatattagct ttttccgaaa ataaacaacc tgtaactgca
    19201 aaaaaagaaa cagtattctc tgaaggcaaa ataaaaactc gatatatatt agaggtagaa
    19261 actaatttta aaaacagatc ggagtaatgg ttatgctttt taatgagaca caattatggt
    19321 ttaaatttga cccttcgaat agatttatca aagattttta taaagtatgg aattcagaag
    19381 ttttcttttt agcaatcgaa gatagcttat taattaatct cta
//
LOCUS       DAPBCF010000050        17764 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.051, whole genome shotgun sequence.
ACCESSION   DAPBCF010000050 DAPBCF010000000
VERSION     DAPBCF010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17764
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.051"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(46..756)
                     /locus_tag="RD508_002163"
     CDS             complement(46..756)
                     /locus_tag="RD508_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736711.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGDESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(774..1270)
                     /locus_tag="RD508_002164"
                     /pseudo
     CDS             complement(774..1270)
                     /locus_tag="RD508_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(1307..1759)
                     /locus_tag="RD508_002165"
     CDS             complement(1307..1759)
                     /locus_tag="RD508_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7736712.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWSFVKKGNKRIY"
     gene            complement(1894..2499)
                     /locus_tag="RD508_002166"
     CDS             complement(1894..2499)
                     /locus_tag="RD508_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDT7736713.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(2949..3569)
                     /locus_tag="RD508_002167"
     CDS             complement(2949..3569)
                     /locus_tag="RD508_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HDT7736714.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(3571..4440)
                     /locus_tag="RD508_002168"
     CDS             complement(3571..4440)
                     /locus_tag="RD508_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HDT7736715.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANKAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(4463..4870)
                     /locus_tag="RD508_002169"
     CDS             complement(4463..4870)
                     /locus_tag="RD508_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDT7736716.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDRHKLAELYEQVGLKFSELHENDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(4889..6178)
                     /locus_tag="RD508_002170"
     CDS             complement(4889..6178)
                     /locus_tag="RD508_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7736717.1"
                     /translation="MSVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINDQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     ILLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(6205..6507)
                     /locus_tag="RD508_002171"
     CDS             complement(6205..6507)
                     /locus_tag="RD508_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7736718.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(6532..8625)
                     /locus_tag="RD508_002172"
     CDS             complement(6532..8625)
                     /locus_tag="RD508_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7736719.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLEEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(9114..9842)
                     /locus_tag="RD508_002173"
     CDS             complement(9114..9842)
                     /locus_tag="RD508_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HDT7736720.1"
                     /translation="MGLCLFALPTQGFAVAGGHGGGTSSGRSSGRGSFGGRSYGGSYF
                     GSRSYGRDSYGYYGPSTGPSSYEQTGFLALAVLSVGGVSAFSIVKNKRQKKRLKSEIL
                     SRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFAEHQKVLQKNKAD
                     GVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLISGSKTQRQYFSQ
                     IWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(9987..12608)
                     /locus_tag="RD508_002174"
                     /pseudo
     CDS             complement(9987..12608)
                     /locus_tag="RD508_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298916.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
     gene            complement(12722..14053)
                     /locus_tag="RD508_002175"
     CDS             complement(12722..14053)
                     /locus_tag="RD508_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7736721.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRVMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKANFGQLNELVPFGFAGMIASFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKNAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQSGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFVGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(14019..15497)
                     /locus_tag="RD508_002176"
     CDS             complement(14019..15497)
                     /locus_tag="RD508_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7736722.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLKNPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(15802..17637)
                     /gene="tdc"
                     /locus_tag="RD508_002177"
     CDS             complement(15802..17637)
                     /gene="tdc"
                     /locus_tag="RD508_002177"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HDT7736723.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEQVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     EQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIQ"
BASE COUNT         5052 a         3809 c         3017 g         5886 t
ORIGIN      
        1 aaaaaaaaaa cggcaatgaa tgccgctctt cttatttcga ttcttttata attctgcttc
       61 tgattcatct ttggttagtg tgtgtctaac actagttacg ccaaatgttt gatcgatttt
      121 ttccttcaac gcttcgattg cctgtgcgcc acgtgccgct tgttcagcat tgatggattc
      181 aatgaccagc accgctgctt gtgtttcttc cgtcagcatc gttctttggg cttcacgcca
      241 gttgagacag cgacagatcg ctccttgttc atcatagtag atgatttctt ccggaagtgc
      301 cggagcatcg gaatctgcac ctaaaggcag gaatgattcg tcaccttggg cttttcctaa
      361 atgcagattt cctgcgatct tttcgatatc ttctccgccg caaggtacgc caaaagacaa
      421 ggaaatacta ttatagatat ctacaagcgg attgattggg aaaaattccc gttcttgatt
      481 tgcacgtttc agtaaagctt caatagaaga acgtgcacct tttttagtct tgaatgtggt
      541 aaatgcctga cgccactgag caatgacttc gttttggctg aatgtttctt ctgtaaggta
      601 atttcttgct tcttttgctg cctcattcaa taattgatga tacgtttctt cactttcttt
      661 tgttacgtgg ttatcgatac catttacgga taagatttcg atggttgctt caggaaatac
      721 ttcccagaaa ttggtatcca ctattacttt tttcatctgt tcacacctct tgattagaat
      781 aattgcttga tgaatagata gtctgtttgg ggatcatctc ccatataaaa aacatgttcg
      841 ctgtatttga taaatccttt tttacgataa aaagcgagcg caacatcgtt gtgttcccaa
      901 acaccgagcc aaatggctgt tttttgcttt tcttttgctt tttcaatagc tgtatctagt
      961 aaaaatgtac cgataccttg atgtttaaat ttttttcgta catagattcg ctcgatttct
     1021 aaaaaatgat cagccatttc ctcagattga ctcgttcctg tatttagttt caggtaaccc
     1081 gcaggctctt gatcgatact cactaggaaa aaatctgttt ctttatcttt tagctcttct
     1141 gtaagttttt ctagtgcata agcttgtgtc aagtaatcag ctaaatgctc cggtaattat
     1201 cttttccaaa tgtatctgta aatgtttcga tactaatttg ttgtagtaag tctacatctg
     1261 aaggcgtcat ttttcgaatt tcgtatttat tcacggcttc ttcctttcaa tagatccttt
     1321 tattgccttt tttgacaaaa ctccaatctt cgctaacatt cttgcatact ttatttaaaa
     1381 gatattccaa ttgttttgct tcttcgtcag aaagaccatt taatgcgact gcattggagt
     1441 agttgttttc tcgaatgatg aaaggataga tttctgctcc ttttttagtc ggatagagtt
     1501 tcttgatttt tttattttct ttatcttcca aacgttcgat catcccattg gattctaatt
     1561 tcttgattgc tcgggcagtc gttgtacgat ctactttgat catttctgct agtttttctt
     1621 ggatgattcc aggattttcg caaatacgta ctaaataaag atactgtcct cttgttaaat
     1681 cgacttcttt gaattcgata ttgctaatag agtctagcgc tcgggcaatc attccgatgt
     1741 ctcgaaggat ttcagccatt tcatcccacc tttattttgt ttgtaagact agtttacctc
     1801 tttttgttgc aagtgcaact atttttaata aaaaaatcaa gttctttttt aataactagt
     1861 aaagtatatt cttttcttct tttacgaaaa agctcaatca caatagatct ggtttttgtt
     1921 ttctaaaata agtaactgtt tcttcgttgt tcgcttttct gatagctttg gcaactcttc
     1981 tatactaaaa aatcccatgt tggaagtttc attattctca ataaacttgg cctcttcacc
     2041 gtggatcgca caagcaaaaa caagtttata atactgaaaa agctgtggaa tatctttttg
     2101 tttattcgta tcaaaaactg ctcgcaactg agtagtttct actgttaatc ctgtttcttc
     2161 atagacttct ttacgcacat tttcttcagg agacaatcct atttcagcaa atccaccagg
     2221 aagtgaccat tctttcgtcc gtttatcttc gattagtagg accttgccat cttttttgat
     2281 ataggcacga acatctactt ttggtgttgg atgtccttct ccaatcgttg tgagcgcttt
     2341 tatttcttcg aaagtttctt ttcctatttc actgatcagt tccaatgaaa tcgtccggat
     2401 ctcctcaaaa cgctctttat caaatacatc ttttccataa tatagaccag cttgagaaag
     2461 tgcgagtagt cttttgtatt gagccaactt cttgttcatt ctcttccctt cttttttagc
     2521 aaatgtatga ctatgtaatc aagtatagaa gactggttta attacggcaa ataaatataa
     2581 tgaaatctgc aataaataaa agaatgttaa aaaactcgag aacaaaagac attcgacttc
     2641 tctggggctg tgaataaatg gcgttcaaaa gcttgcatct gcggtaataa gccccatcaa
     2701 acgaaaaata tgacgagcta ttcttgtctg gctgttctta ttaattgagg caggacagct
     2761 ttttcacaac ctccccacta aacggtgttc tcctaccaac tcctcggtca caagtcacaa
     2821 tattcatcaa acatgagaag ctgtttcttt gaaattgctc cttgtgactc ggagctgaac
     2881 gacaggctca cgacctctcg gtaaacggtg ttcaaaagcc aatttttcga tattaagcca
     2941 tttctttgtt acttattgtc attgatttct ttttctaatt tatccaatag tggagtgtaa
     3001 tccacttgag tatagtctgt tacatcaaat tcatatagtg ttcctaactg gaatttgtca
     3061 tattttcggt cggcgatgat ctttttgaat gcttctttcg taatatgatt ggtccctttc
     3121 gttcgatctt ccaatacgtc accatagtga taatgatcca tgatatagct caaatgacga
     3181 tctgattcac gatcacgttt gtaccgacgt tgccataaca cttcaaagtc tgctgttagg
     3241 cgaatcgtga tcacctgata tccgtatcta tctgctaatt cttggagtcg tgctttttgc
     3301 ttatcactaa aaggatactc ggacacaatc actttctttc ctgcttccat atacaaatca
     3361 agtgctttgt aatagaaagg ataaactttc gtcctttctt gttccgcccg ttcttccaaa
     3421 ttgttaaacc cgatggattc tgcatagtat tccttgattt catcgagcgt gatggcatac
     3481 atatctggaa atcgttcccg tagtttattc ataagatatg tttttcctgt accaggacta
     3541 ccagccagaa gaatgaaata ctttttcatc tcatttattt cctaagttaa ttggactttc
     3601 caagttcata aacagtccaa tcttatgctt gacaatttct tttactgctt tatttgctgg
     3661 aatcacatta tggcgaagag acttgttgat ttctgtttca ctaaaggttt ctttagctac
     3721 tttcgtccag ttgactaaaa gctccgttcc aacattgaat ttgcggatcc cgttattgat
     3781 caattcagga taatcttctt ctttcacacc tgttcctcca tggataacta gggggacatc
     3841 aactactgca tcgatttctt tcagcaaggg aatgtttact tctgtttttg atttgaattg
     3901 tccatgattc gtaccgatag caatagctaa tgcatccacg cctgtagctt ctacaaattt
     3961 cactgcgtct tccggtcttg tatatacctt gtcattttca gcgacatgga ttccttcttc
     4021 tgtaccgccg attgttccaa gttctccttc tacggaaaca ccgtgcgcat gggcatattc
     4081 tactactgct tttgtcttca agatattttc tttgaaaggt agatgggacc cgtcatacat
     4141 gacagaagta tatccgctat cgattgcttc tttgatatca tcaaagtctc gggcgtggtc
     4201 taagtgtaag actgcatcaa ccatttcttc ttctgcaata gctgtcatta cattgactaa
     4261 cacatgcatg ccgatatatt tagcggtatc gacacttgtt tgaataatga ttggcgaacc
     4321 catttctttt gctgcgccta gcatggcagg aagcatttct aggttatgcg tattaaaagc
     4381 tccaactgta aaattcaact cttctgctgt ttttgttact tctttcaatg ttgtatacat
     4441 cttttattgc caccttatct ttttatttgt ttcctttgat cgttacttgt tttgcaattt
     4501 gtcgcatctc atccattttg cccatgtagt aatcgatccc ttgatcatca ccagcacgag
     4561 cagcatctgc acgcttctgg ttatagaggc tcatcagttt tttataccca tctccgatcg
     4621 tctgtttatt ttccaagctc ttttctaaat attggatggc ttgatcgttc tcatgcaatt
     4681 cagaaaattt aagtccaact tgttcataaa gttccgctaa tttatgccta tcttgggtag
     4741 tggaaatctc ttgtttcaat tgtgtaatct ctgattgaat cttttcggtc gcttctggcg
     4801 atagggcttt ttcttctttt gccagaactt ttttcggttc tttttctttt ttcttaaaaa
     4861 atccaaacat cattttccct actttcaatt aaaacgcttt caaaactggg cttaagatcc
     4921 aggcatataa gagtgctgcg gctactgtat ctacatcggt tgctgtagca ttgatgaatc
     4981 ccatcgaatt aaagatcgtt actagcaaag cgggcaataa tgtaataaag aaaccatgag
     5041 caataccgcc aatgatcgct cctcggcgtc cgccaactgc gttgccaaat atccctgctg
     5101 tccctccggc aaagaaattg gttagcatac caggtaaaat catcgctaag ccgaacatgg
     5161 gcaaagtaaa catggcaata atcgtaccaa tcgttgtcgt aatgaaacct aaaatgacgg
     5221 catttgggct ataaggaaag aaaactggac aatctaaggc agggatcgca tcaggaacta
     5281 atttcatagc tatccctcga aatgccggca cgatttcacc taacagtaga cgtacaccag
     5341 ctagcaatat atacacaccc actacgaatt ggatggcttg taaaaaggca aacatgatat
     5401 agttttgatc tcctgataat tcagaagcga atggttcgcc tgcaaataaa acagtgatga
     5461 tatatagcgg gaccatcacg accatgacag acaaataagt atcttgcaga aattcgaaat
     5521 gtgtcggcaa cttgatatct tcgatcgact ttttattttc gcctttctca ccaaaaagct
     5581 tagcaacacc ggcttcaaat aagtacccga tcgtacaaaa atgacctaaa gcaatatcat
     5641 ttgatccagt gattttacga atgatcggtt gcgctactgc cggcatagca atggcgaaac
     5701 aagctccgat aaaaccaccg accaagatca atacgatccc tcgcagaccg gcaaaatagc
     5761 caaagactgt cgtcatcgtt gccatccata aaattgcttg accagttaaa aaaatgtact
     5821 tccattttgt gaaacgagcc aaaataatat tgaatacaaa aatggctaag aacgtcagtg
     5881 caatatctct acctaaaccc aaatcattca ttgcttgatc attgatagat tcaatagaag
     5941 ggatgatccc ttgcatatga aatccttcag taaagatttt cccgaaataa gttaaacttc
     6001 caacgatgat gctcgaaccg gcactcaata cttgaaatcc taggagtgtt tttaacgtgc
     6061 cagagatgac ttgtcctgct gatttcttct gcagtagtag acccaacata gcaatcaatg
     6121 caatggtgat cgatgcctga gtcaaaatat tttcgatgat aaaattgata acgctcatgt
     6181 ttttaccctc ttttcttttt gtatttagat aactccctta tcttgcagaa ctggggtgat
     6241 tttttcttca atttcatttt ttgaaacaat atttttcaaa tagatcatcg ccgttttagg
     6301 atcaactgcg aacttttcga actgcgaacg aaaattttct gctgtgatga tcacatctgg
     6361 tttcatggaa actgcggaag aaatatcaca atggtccagt ttggcttcta ctcctaattt
     6421 gttcaaaaca tcctcagcag acatctgtgc tgcaaaacta cttcctaaac ctgcgccgca
     6481 tacgaataaa atgttcaatt tgttcatctt tgttctcccc cgtatcattt attatttctc
     6541 aactactgaa aaaagcagtt gtttgaaatc ttcgatattt gtgcattcaa tcaatcgatc
     6601 caacttctct tcgttgttga tcaattcaat tagttctttc atgatgttca gatgggagta
     6661 ggagtctact gctgccaaac aaaaaataat ctttactgga tccatttcag gattaccgaa
     6721 atcgattggt tgctcaatcg tagctacgct gactcctaat ttattgaccc catcttctgg
     6781 tcgggcatgg gctagtgcca tgtgtttgcc aatcacgata tacggtccgt aatcattcac
     6841 tgcacgaatc atcgcttcga catagcgctc ttcgacaatg ttttctttaa ccaatggtct
     6901 agcagctagt tcaatcgatt cctcccaagt agtggctttt tctttgatca tgatattgct
     6961 gtccgtcaaa atatctttta acataggctg gatctccctt ttgttgattt ctaaattgtt
     7021 tgtttcgaat aatttttcta acttgccata gatgattcga tctactcggc caccactttc
     7081 tttcatgaca tctattattt gagtgaataa ctccgtcgat tcatgactgt taggctctaa
     7141 ccgctgtagt tcttcatttc ttttcaaaaa gtcttctata accaagatat tcgtctcagt
     7201 taaaatcgga tcgacaacta aaagcggctt atttcgataa ttcaattgaa aggtgctgaa
     7261 aaccagattg acatccaatt tatctactaa ttcgatttct tttgaactta aaactgcagt
     7321 aatctcgatc tgaggaaact tttctttcag attctctgct aacagatttc cagtagccat
     7381 cccatggtta cagacaacga ctgatttata aacataattc aagtctcgct tgattacact
     7441 ggcgatcgtc gaaaagtgga tgacaagaaa agctatctcg tcctccagta tcttgccacc
     7501 aattacttct tcgatcgtag gaacaaaatg agtgactgcg cggtagattg ggaaataatt
     7561 tgttcggatg ttttctttca atggattcat gacttggata tgattcttga ttcttacaat
     7621 cagtgcagcc atgtgcttat agagattttc gaataaggct tcttccttta gatggaaagg
     7681 tacgtgtgtc tcgttctcta caaattggat caattggatc gttagtaatt gagcttgtac
     7741 ccactcgatt gaattggaga tatctctagc attgaacgtc tcaatagtga aacgaagata
     7801 atttctttct acttgcggga cattgtccaa ttgaaattcc tcgatcatgt ggtcaataaa
     7861 tgcagaaaag ctactgtctt ttatttctgt atttttccaa ttaatggcag agataaattc
     7921 atgtttcctg attcgctgga tccagatcaa tgtaaaaagc aggatttgtt ttttataaat
     7981 atcatcttct tgtttcaaca acttattgga atagatctcc tgtatttttt tgatttcctc
     8041 caaaggaaaa taatggagaa agattttttg agccggtgtt aattgtgcat cttgattcat
     8101 aaagaagtcg gtcattccca gattctgatt gataaaatca tagatcatcg tacggataga
     8161 tcgttctgaa cctttataaa ccagtccttg ctttccataa ctgacgatct ctatcccata
     8221 actgaccagt gttgctcgta accgtctcat atcttcatct aatgtacttt tagagatttg
     8281 aaattcttct tcttttttgt ttagatggat cgggattcgg ctgtaagcaa cggctaaaac
     8341 tagatcaaaa atacgttcgc gccgattcaa aaagccgtct ttcacatctt ttatttcagt
     8401 ttctaatcga gcttgctttt ccttttccag cttcaacaaa aaacctttgt tgcgaattgt
     8461 acggatctcc ggaagctttt tactgctcaa ccagatattc gcttcaagaa cttcctgacg
     8521 aatcgtccgc tgactgacat tgaactcact tgctagatgt tttgctttta ctggatattg
     8581 ggctgtcatg attctgtgaa gtatttcaat tgttcttgtt ttcatagaaa tgatctcctt
     8641 ctgatttcaa gtatatggtt ccgcttacat aataaaaagt agatatttct gccacttgaa
     8701 gtggaaagaa agtaagcaaa gcaaacaaaa aataagccat atgctttttc atctcctcaa
     8761 cgaaaaagac atacgcctat tattacaaaa attttgccca tctatacaaa aaagaggttg
     8821 tgaaaaagct gtcctgcatc aagtaataag aacaactaaa ctaaaatagt gcttcctatt
     8881 ttttgtttgg ttgttcttat tatcgcagat gcaagctttt aaacaccatt tagtggagaa
     8941 gctgtgacag agatgttcag ccttgagcga taagaagcga ttttgaaaaa tcgcttccca
     9001 tattttacaa aatcgtgcct tattgccgat aggctatctc tggaacaccg tttattcaga
     9061 aaaaggagct gcgacaaggc ttttgtcaca actccgttca taaatatttc ctgtcaatcc
     9121 agcataatcg gttgaataaa atcggcttgc catctttttt ctttctcaga aaaatcaaaa
     9181 taccatatct gagaaaaata ctgtcgttgt gtcttacttc ctgagatcaa tcgcccatct
     9241 tttcgatcga ctgaataatc acagcatctg aaatcaattc ggatggcaaa actattttcg
     9301 tggatctgtc gataatttcc tacttcctga atagttattt ttttagtatg atttcttaca
     9361 ccgtctgctt tgtttttttg cagaactttc tgatgttcgg caaacagctt gtctgtataa
     9421 cagcttctgg ctttttcagg agtttcttct tcccaagcgg attggatctt catgaatatc
     9481 ttttggattt ccaaaaactg tgctttcttt tctttagccg ttcctgacat gcgggacaat
     9541 atctccgatt tcagcctttt cttttgtctt ttattcttga cgatagaaaa agcagaaacc
     9601 cctcctactg acaaaacagc taatgcaaga aaccccgttt gctcataact agaaggacct
     9661 gtacttggac cataataccc ataagaatct ctgccgtaag aacgactgcc aaaataactg
     9721 cccccatatg aacgaccgcc aaatgaacct ctgcccgaac ttcgaccgct agatgtacct
     9781 ccaccatgac cacccgcgac agcgaatcct tgggtcggca gagcaaacaa acataggccc
     9841 actaacaaaa tgattgctaa ataattgatt ttttcattgt cttcctcgtt atcttttatt
     9901 acaaaaaact attttatcat agccttgcta aaaggaagag tcaataacca gatgcataaa
     9961 ctgttttttt agcaattttg tcttatttag tcattgagta acatcggaca gatgtatgtg
    10021 tcggcagtcc ataattcctc tatcttcagc atgaacaagc ttgcagacaa gagatctgcg
    10081 cttcctccag gagagatttg gttttcctga caaaagtgca acagtgctgt aaatggacga
    10141 tttggtaaag cactttgact agcagcatga gcaagttttt gcatttccac taacgttttc
    10201 tgatcactgc gatgcaatac gcatgtgtca tctagcgaac tcatcaaaac taacaacata
    10261 tgcatttgtt tctgtacata tgaatcatta tctagctcct tagctgcttg gattgcaagc
    10321 ctgatatgcg gataccctaa tatcgcttct tcatatgcac catttacgcc atatttttgc
    10381 ttcaccctat gaccatgagt ggttttttta tgacgatatt ttgtatcagg aaaagcagca
    10441 agcttgctga catcatcaag tattttcgat aaagaaaaag gctgttccat actgattttt
    10501 tgtgcaatga cactgatcaa tagccccatt gcccaaatcg ctcctttatg ggtattgatg
    10561 ccatttgtag caatcagcat tgccttttcc gcttttcgcc caatctcagc aattctttct
    10621 cttaactcct gatcaatagc ataatgccat gctatttgag ccatttcttc aaaaaaagga
    10681 gttagcgtct tagcagactt atccaaaatg cgccgacctt cttttacggc ttttgcgatc
    10741 gtatggaaat tatcatctcc taaaaccata tcagctgcct gtttgcttac ttcactacct
    10801 ttgattccca tagcgattcc tatatcggct cttttcaaag caggtgcatc atttacgccg
    10861 tctccggtca ttccgacgat ttctccattt ttctgcaaag ctttcacgat tcgcagtttg
    10921 tgttctggtg tcgttcgagc aaagacgtcg acttttggta cttgtcgaat caactcttct
    10981 tcagacataa gatccaaatc gatcccttct aaaactttag cagtatgttt taagccaatt
    11041 tgttccgcga tcgcttttgc tgtatctttg tgatcccccg taatcatttt cactgagatt
    11101 cctgcttgtt ggcattcctt tacagctttg actgcacttt cttttggcgg atcaatcaac
    11161 ccagcaatcc ctgcaaaagt taattgggtt aaagactcat gcgtgagttc ctgtttcgaa
    11221 tctacttttt tgtaagcaaa tcctaaaaca cgctgacctt ttttcgcaaa cgctgtggct
    11281 gtttgacccc atgcttctta ttctgaagaa gaaagagttg atttagccaa taatacttct
    11341 ggcgcacctt tgacgtaaat cacccctcct ttttcctccg catgcatcgt tgccatatat
    11401 ttgtattcag agctgaacgg aatttttgct tctatttttt tcaaaggcag atcggctgtt
    11461 tcggtgtggc gaatcagtgc aagttctgtc ggattgccac ttaaattttc tgttttctgt
    11521 tcttctttcg tctttaattc ctgacaattt ttcataataa acagtacgcg agtttcttcc
    11581 tttgctgcta catccacaac tgtcatttca ttttttgtca atgtccctgt cttatctgaa
    11641 cagatcactg tcatagaacc taatgtttct acagaaggca gtcctttgat gatcgccttt
    11701 tcttttgcca tttcatgtac tccgacagat aggatcatgg tcaacacagc tggcaatcct
    11761 tcgggtacca ttgacaccac caaagcgatc atagctgaaa gaaggatatg ccaatccatg
    11821 ccatagcgga atgttgtaaa aacaactaag aacaagatca aacaaagaat gccttgaaaa
    11881 atttgtttgt tcaatcggtt gatcttcttg atcagaggcg tcgtttgttg ttcgaccgat
    11941 tgcagtgctt gattgatttt accgatttct gtcgtgtttc ctgtttctac aacgacaccg
    12001 actgcagaac cagattgtac aagcgttcct gaaaaagcca tatttttttg gtcaccgatt
    12061 gattcttctg ctgccaaaac ggaatgattt ttttcagatg cttctgattc tcccgtcaaa
    12121 atcgattctt ctactagtag atcatgtact tcgatcaacc gaacatctgc tggaacgacg
    12181 tctccggcac gtaagacaat gacatctcct tttactagtt ctttcgcagg gattttttct
    12241 tgcatcccgt tcgatagtac tatcgcttct tgtcccatca gctgcttcaa accattcaac
    12301 gattcttctg cttttctttc ttgccaataa ctaacgagtc cgttgacgat cactacgaat
    12361 aaaataatac ttccttcgat gtattcgctc gaagcaaatt tcaaaaaaga ggcaatgatc
    12421 aacacgatca tcagcagatc agtaaagtgt tttgctattt ttttccatcg ttttgtctgc
    12481 tgtcttgctt ctatctcatt atatccttga tcagtcaggc gtttctgccg ttcttcttgc
    12541 gacaagcctt ctgttgatgt ttgatagttt ttcaatacat cttctaccgt caatctgtac
    12601 cagttcatcc tatcccctcc tgtttaattg atactgttat tatacgcagg gaagtttttt
    12661 caggcgtatc gattatttca ggggggtctg aaataattcg ttttgcagaa tgtatctggg
    12721 cctaactgat atttctattg cttattcttt tatatacaaa atttaagaat acaaaccaga
    12781 taaccaataa aaaaggaata aagcgtgtcg tgctttcgaa taacaagctg aaagcaattg
    12841 aagtaaaaaa caccaacaaa gcaagatctt tatatctttg tgtagtgttc cgtttctttt
    12901 ctttaataaa ttgaacatgt gcacacaaga tcgaagacca cacaaataga aaacaactcg
    12961 ttgtcatgcc tgccaaaagc tgaaaaaaca atcgactatc agctacaaaa aaatgtagac
    13021 aaagaccgac aaaaaataac atccctgtaa ttaaaatacc gtgtaaaggt acgcctttct
    13081 tagaaagcgc acaaaaccaa tggggcaaac ttttctcttt tgctgtttga tataaaatcc
    13141 tgctagtact gtagactgca ctatttgctg aggacaaaga agcaaccaaa atcattagat
    13201 tgacaattgc tgctccgctt tggcaatgga tcacttgcag catagtcact aaaggacttt
    13261 cttttaaatc taaacaatgc catggaacaa caaataaaat cgacaaaatc gttcctatat
    13321 agaaaaagag gatacgccaa ggcagacagt tgattgcatt tttcaaattc ttttgtgggt
    13381 cactcgtctc accaactgtt aatccgatca tttcaattcc agcaaaactg aataaaacca
    13441 taggaaatga agcaatcatt ccagcaaagc caaacgggac taattcattg agctgtccaa
    13501 aatttgcttt gattccaata gactgggtat gaaaatctga gacactcaat cctataccca
    13561 ataagataaa aaggaaaatc cccaagatct tgatgattga gaaaaaagat tccaattcac
    13621 caaaccactt gactgcaaca aggttgactg ccattaagat cattagtgcg ctacctccgc
    13681 ttatcaaagc tggtacatgt acaaaccaga aatggatata caatcctatt gctgttaatt
    13741 ccgcaagtcc agctccaagc cagcaaagcc aataagtcca attgacaaaa aatgcccact
    13801 ttttgcctaa ataatagtca acgaaatcac tgatagagtt aaatgtacta tttgctaaaa
    13861 ataaatcacc catgacccgc atcaaaccat aaatagccaa accgcatatc aaataaacga
    13921 gaataacagc tggccctgct gatgcaattg cctttgctga acctaaaaat aatcctgttc
    13981 caattgcgcc acctaatgcg attaactgga tatttcgatt agttagagtc cgtttcattg
    14041 ccggtttttc catcaagttc acctttttct ttttcaagca gcatggcgac ttcctgttcc
    14101 caagaaggtt tctttatttt ttcaatacag agtggtacta caaacaaaat gacactgatg
    14161 gctgtgactg caattagatt gatccatgtc ccagctttca tcgtcagtcc gacagaaaat
    14221 ccgattgccg caaataaaac aataacgaca gtccaaactc caagattgct ctttttctct
    14281 ttttttccaa ttctaaatgg tcgattcaac tttgcatgtg tataacgcaa tctcaaaact
    14341 gcgatcccca tgatgacata gacgatacag tagataacag tagttgaatt tacgagcatc
    14401 aaaaatgctt gattgacgcc aggaatcagc aaataaaaaa gtgcaaagat tgagataatg
    14461 acagactgag tcaaaataac ggatttggat acgtcaaatt gattcgtctt ccaaaaattg
    14521 aattttggtg gatacgcacc ttttctagca ctttctgtca ctgtctttgc tggtcctgag
    14581 gcccaagcag ataattggac tgctacacca atgaagacaa gtaaactaaa cagattcaca
    14641 ataagatgtg gcaaaccaag aatttggcaa taaatcgaaa tagattgcgc gatattattc
    14701 aattccattt gtccttttgg tacgacattt gctacaacta aagcattcaa aatattgacg
    14761 aaaaatataa aaattaacgc ggcaaatact ccgcgaatat acgttttaac tggatttttc
    14821 aaccgagtga tatacacaga ggacatttcg ataccagtaa aaataaacat gatcggcgca
    14881 aaataaacaa atgaggatgc agtcgtagta tctggtatta atttgtccca tgaaaaactg
    14941 cctaatgttc cggttggtac gatcccaact ttgatccacg cagcaaaccc taataagagc
    15001 atcatcgtca aaggcacgta caatcctaac caaacaccga cttttccgcc gatttttgcc
    15061 atatcaaatt tcaaattcaa aaaagtgatg atccaataaa cgactaaaat gacaactaat
    15121 gtaaatttgc tgttcaaacc aagcggcaca ttatcgataa tattaccaaa caacggagca
    15181 agtgctgaag cgaccatcac catcccagga aacatttgga cccataacag ccatgagaca
    15241 acgaaccccc atttttttcc tagagcattc gatacccaaa gttctggacc acctttttgg
    15301 ggaaacattc cggcaaattc accagagatc aatgagattg gaaaagcgta caataatact
    15361 gcaaccagca tgtaaaaaat catcgtccag ctcgttgctg ctacatctgg aatatttcgt
    15421 acacttgcta caagggcgca ggtcattccg ataaaggtca tggtcgtgat ttgctttgat
    15481 gaaccagtat ctttcatctt tattccttct ttcaatagcg acatatgttt ttgttttctt
    15541 ttatttttgt tcaagaacag aaatgacaag gtttcatcga ttcagtacaa aacccagtat
    15601 caccgaaaca tccattgaac gatcttagtg aactgggttt gatacatgaa acgaacgatc
    15661 caacttatag aacgttttat aaaaaagaat atcttggcga ggaatatatg aaaaacaggg
    15721 ggaaatacaa ttgttttgat gaagcaaata attgtctgtt ctccatatgt ctcttgttat
    15781 tctttcacac aaaaatcagt tctattggat gatttcgttt agtttctttt ccattgcttt
    15841 ggcgatttct tttgtataaa aattgaaaat tcgatcatca ttcaaataag gagtcatgat
    15901 agccgcacgt agcagagtga ttttctgttc ttttttccat tcttctttcg ttagacccat
    15961 tctttcaaca aaacgaatcg gagaatcacc gtaatcttct tgtgtaaatg tagtatgaga
    16021 agtaataaac cgttcaccat aaacatcgcc atccatataa gaagaccgat cgaacatttt
    16081 ttcatttaat tcattgatag cgttcaaatc tgtacagcct tgttctttga atacccaatt
    16141 gaccatatta aaatcaggat gattcaatgg atagacttcg attgtttttc ctttaacagt
    16201 aaaagtcaga tgatcgagaa attctctgaa tctttgagct gcctcgattg aagccccaat
    16261 caattgacca tatccggtca cattcaatgg caatacacga tgtgctgtcc agactgcggc
    16321 ggcggttgct ccagcttttg atccttccaa aatataagct cctaacatat ctggagcctt
    16381 tactgatttt tcaaacacat atggcgcgaa ataagaaatg atatttctca tatttttatg
    16441 tttgattacg attcctccag cagcataagg gacatagccc atcttatgag gatctatcgt
    16501 gacagaatcc gcttctgaaa tagctctgaa cccttcatat acctctttgt caatcgttac
    16561 gcagtggtgg aaaacatgat gttcttcaaa gaattcagct aaggaagcat acggcacaaa
    16621 ttctcctgct tcgtttagaa acagtgaacg cgcatagccg ccatatgcgg catcaacatg
    16681 taaatagaaa tagatccctt catcttttaa cctttctctt aattggacga ttttatctac
    16741 actgtctact tgaccttctt ctgtcgttcc tacgacagca accacaccta gaattgggat
    16801 tttttgttca gctaattcac gaattgtttt ttccaaagca ttaatatcca ttcgataatc
    16861 ctcttgaact gggatagcaa ccatctgatc taagcctact ccgcaaatat ctaacgcctt
    16921 catccaagaa tagtgttttg tttgaggcac cagccatttc cctaatcttt ggatattttt
    16981 tccgctacgg gaagaagctg ctttgacctc atccatttct tcgtccgtaa agctttcggt
    17041 catttccaaa atttcttcaa cagataaatt caaaagttcc cactcagaca tttttttcac
    17101 ttgttcaggc agcacttcct tgacagctaa aggaatcgat ttgatgcagc gggcgtacca
    17161 taatccttca agattagcaa tagaaccatc tgctgcaatg tgtccccatc cgtctgtcat
    17221 attgaataat gaagcaaaat cctgtcctac ttctgcttcc atttgcgaag ttgccataga
    17281 agattccaat gcaacattat ttgggttcca cagcatcgca tagttgtaag ctaataaagc
    17341 aggcatcaat gtttcagcat tcatttgtcc ccagtaacgg cctgctgaat gccatgggat
    17401 cgatcctgcg cgtaatcgct gactgacttc atccaagacc tctatcatat ggtcgcgggt
    17461 ggctagataa tctggagtga gcttatctcc ttcgctaatt gcaggcatat ctgaaggaat
    17521 ataattttct ctccatccaa gatgttcatc taccatcttg ttcaacaaca ttttataaac
    17581 tggtccattt tcagctttgt cgcctataaa gacggccttg atatccatat ctttcatttt
    17641 tcttccctcc atattttgtt ggtcaatgtc tcgcagatac atgtgtttat ctgtaacacc
    17701 tcttcactat agcgccaaaa atgagaaatt tttttttata acatcaaatc cacgtagatt
    17761 ttta
//
LOCUS       DAPBCF010000051        17755 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.052, whole genome shotgun sequence.
ACCESSION   DAPBCF010000051 DAPBCF010000000
VERSION     DAPBCF010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.052"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..1350
                     /locus_tag="RD508_002178"
     CDS             <1..1350
                     /locus_tag="RD508_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7736724.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2815
                     /locus_tag="RD508_002179"
     CDS             1484..2815
                     /locus_tag="RD508_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7736725.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFIFSFVKLS"
     gene            complement(2802..3761)
                     /locus_tag="RD508_002180"
     CDS             complement(2802..3761)
                     /locus_tag="RD508_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7736726.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            4005..5456
                     /locus_tag="RD508_002181"
     CDS             4005..5456
                     /locus_tag="RD508_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HDT7736727.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            5805..6437
                     /locus_tag="RD508_002182"
     CDS             5805..6437
                     /locus_tag="RD508_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HDT7736728.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            7025..8464
                     /locus_tag="RD508_002183"
     CDS             7025..8464
                     /locus_tag="RD508_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7736729.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            8759..8977
                     /locus_tag="RD508_002184"
                     /pseudo
     CDS             8759..8977
                     /locus_tag="RD508_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            9226..9441
                     /locus_tag="RD508_002185"
     CDS             9226..9441
                     /locus_tag="RD508_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736730.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(9658..9914)
                     /locus_tag="RD508_002186"
                     /pseudo
     CDS             complement(9658..9914)
                     /locus_tag="RD508_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10101..11012)
                     /locus_tag="RD508_002187"
     CDS             complement(10101..11012)
                     /locus_tag="RD508_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7736731.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(11031..12035)
                     /locus_tag="RD508_002188"
     CDS             complement(11031..12035)
                     /locus_tag="RD508_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDT7736732.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(12032..14155)
                     /locus_tag="RD508_002189"
     CDS             complement(12032..14155)
                     /locus_tag="RD508_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7736733.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(14160..16607)
                     /locus_tag="RD508_002190"
     CDS             complement(14160..16607)
                     /locus_tag="RD508_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7736734.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(16594..16983)
                     /locus_tag="RD508_002191"
     CDS             complement(16594..16983)
                     /locus_tag="RD508_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7736735.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(17043..17546)
                     /locus_tag="RD508_002192"
     CDS             complement(17043..17546)
                     /locus_tag="RD508_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDT7736736.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(17559..17720)
                     /locus_tag="RD508_002193"
     CDS             complement(17559..17720)
                     /locus_tag="RD508_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002392227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736737.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
BASE COUNT         5680 a         3310 c         3264 g         5501 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttttcgttt gtcaaattaa gttagacaaa
     2821 tcatcttttg tgacgtaact caaaaatact tccattggtg tccgatagtg taatgatttt
     2881 ctaggaatat gatttcgttt cgatgccacc gattggataa aggtttcaga tacaccatta
     2941 aaatccatag ctttatacaa accatcttta cgtaataagc catttgaatg ttcattcaat
     3001 cctcgttgag aaggtgttcc tggatccgca aaataaattg aaatatcgtt ggtattacta
     3061 atctttttcc aatttgagaa ttcttttcca caatcaaatg tgatggattt aaataagttt
     3121 tttgggacac aacgaaacca ttgattcagc ctattttcaa tgtctttagc ctgtctgcct
     3181 tcgggtttca aggtaatgat gactttagat agccgttcaa ctaatgtgat gaccgcgctt
     3241 ttatgttttc cacccacgat agtgtcacct tccaggtgac caaattcatg atcaaactgg
     3301 gtatagtctg tctttctgtc tcggattgac cggcgaaacc cttgttttcc tcttttttct
     3361 ttatgaccgt ttggttttct ttttcccttc attggtaaat cgtgagtgtc aaaggtttta
     3421 tctttaaaca ttcgatacag tgtgcgtacc gaacaagcaa taggaaactc tgctcgacca
     3481 ataaggacat caggagccca cccttgaaca accttttttt gaatgtattc ctgttgctca
     3541 tcaggtaaaa caatcggatg tcttccgcag ttacgtttgt ttttcttata ttgtttatag
     3601 tagctcattg cgcttccacc agatttaaga aaacgataga ccttataaat agtttgtcga
     3661 gaacgttgta acagattggc tacttttgaa acaggttgtg attgattgaa ataagcttct
     3721 atcattacga gttcagttgg tgtaagatgg ttataggtca tttgtactca ctccttataa
     3781 ttctttcgtc ggaactattt tgagtgtagc acaaatgact ttttttagtt gtctagctta
     3841 attttacaat cggcgtttta aaggcagtaa caggattaaa cattgaaaca taatcgttac
     3901 taaatgaaat caagaaatat actgtattac tcaattcatt gaaaatattt atcataattt
     3961 ttaatagaaa acactattaa agagaaaaaa gagaggtaaa tcaaatgaaa aaatctttaa
     4021 aacttgcatc agcagttata ttaatgtccc aactccttat agcaacacct ttccatgtgt
     4081 tggcaagcga aaattcaaca tacaaaattg caaaagaaag aaccgagacg actgaaatga
     4141 gtaattccga tgtaacagca gagagtagtg aacttttgac aacttcatca agtgaaagta
     4201 gtacgacttc aaatgccgag tcttcaacaa cttcatcaag tgaaagtagt acgacttcaa
     4261 atgccgagtc ttcaacaact tcatcaagtg aaagtagtac gacttcaaat gccgagtctt
     4321 caacaacttc gtcaagtgaa agtagtacga tttcaagtac cgaatcttca acaacttcaa
     4381 gtagtacaag tgaaataact tcttcgaaag tgacaaaacc aaaccatata gaatcttcaa
     4441 aaaaggaagc gccaaaaacg gaaggacaaa caaaaacttt ttcgacacca cagcaaatag
     4501 aatcaacaga atctttccaa tcacaaccaa tactatctgg taatgaagaa attcattttg
     4561 acaaaaatga atctgtagaa aattttatta tgaaaattgg tgagtctgcg agaaaaattg
     4621 gtcagaaata tgatttatat gcttctgtta tgattgcaca agcgatctta gaatctgcca
     4681 gtggtcaaag ccagttagct caggcaccga attacaattt atttgggata aaaggaactt
     4741 ataatggaaa ctttgtcatt atggtaacaa acgaagattt gggtaatgga acgctttata
     4801 cgacccaatc aaaatttaga gtgtatgaaa actatgagga aagctttgaa gattatgcca
     4861 aattattaac taagggaatt agtggaaata aagattttta tgcaggagca ttaaaagcta
     4921 atagtaaaac atatcgagaa gcaactaaat tccttacagg acggtatgca acagatacac
     4981 aatactattt gaagctaaat gaattaatta aaacctacga tttaaccaac tatgataaag
     5041 aagttaaagg tccacaaatg agtaagactg gataccaagt gcctattcat aattattcaa
     5101 taaccagttt gtttggaaat cgtggaaatg aatttcaccg aggacttgat atggcagcta
     5161 cacagggtga gccgattcat gcagttaaag ctggtaaggt tgttaaagca gagtttcact
     5221 actcttgggg aaattacgtg gtgatacaac acgaagatgg atcaaccgcg ttatatgctc
     5281 accagcaaca atacctagta aaaactggag ataatgtttt gcaaggacaa ataattggct
     5341 atgtaggaag tactgggaat agtactggcc cacaccttca tttggaaatt tgcaaagata
     5401 gtagtctttc tcagagcatg ttagttgatc cgaaaacctt attattcgga gactaaaaaa
     5461 ggtaatcaat ctgacaaagt aacaagaaaa tggttggatt cttagacctt tgatcaggat
     5521 attgagactg gaattgatat ctcgattacg atgggtttga caaataaaac aagtccatta
     5581 tcgaatatcg agtgtattat tgccgtcttt atgctcatat tttgagcagg tttcactaga
     5641 tgaaaacaat ttatctatct tgaggatttc gtgtacgtat cgttcagtct tgtattgtaa
     5701 attagtcata aaatcagact aagaaaaatt ggaaatattt ttttctgatt tattaaaagt
     5761 taattgaaat tatatggtac ttctttcttg ggagggtagg tgcagtgaag gaaagatatg
     5821 gtcaccttac tgttgttgag gagattactc ataatggata taaaaaatat cgttgcctat
     5881 gtgactgtgg gaatgaaacg attgtatatc gatcaaactt actaacaggt agaaccaaaa
     5941 gttgtggatg tggaaattat aaaaataggc ataaatataa aaatttgaca aataaaactt
     6001 ttggtaagtt agttgcaatc aagccaacta aactgcgaag tgaaggaact gttgtttggg
     6061 aatgtcaatg tctgtgtggg agaaaaaagt tagtatcggc aaagcgactt ctaaaaggtg
     6121 atgtaaaaag ctgtggatgt ttgaaatcaa aaaagcatca cattgaaaat aaaaaattcg
     6181 gattacttac tgcaaagtat cctttggaca ataactgttc atggaaaaca aaatgggttt
     6241 gtcattgtga gtgtggcagt atgtgtgaga taagttatag taacttattt tttggacata
     6301 ctcaaagttg tggatgttta aaaaggcaag aaacaaggac atgtgttgaa gggacagtaa
     6361 tagagtgtct aacgtcaaaa ttaccgaaaa ataatacaag tggtgttaag ggagtttatc
     6421 gttctaaaga gaaatagatt gcgtatataa ctttaaaaaa aaagaggtac tatttaggat
     6481 cgtatgattc tattaagagt gcagctcaag ctagaaaaga tgctgaaaat aaattgtttc
     6541 aacctttgat tgacaaatat cgaggtaatc attaattatt gtggataata attaacagtg
     6601 atatataaac atctataata tattattcat actattgata tttagtataa tcctatggaa
     6661 ttgaatatca tagcaatgta tttgaaaagc aaattggaaa acaaataggt gcaacaccat
     6721 aaatatgaaa aaattgggaa aaagtagaat ggaaatttgc ttacgtctca cgagatagct
     6781 cacactatta atctgaagaa caatgaagtc gacttttaga aattgctaga agaaagtaaa
     6841 gcgaattatc actagttact atagagtaag ttcaaataaa gcatctccaa cttacatggt
     6901 tacatgagga tatcaaatcg aaattactca agcttcctat ggctagagtc gcgagaagtt
     6961 gttgggcagt agacataggt tatattgttc ttagctacac gatcattaga aaggaaatcc
     7021 tattatgtat agttatcaag aagatgcaaa agtccaaaaa aatcgctggt ggattttgat
     7081 tgctatatct atgtttacct tcatgtccac attggatggc agtattgtca atattgcact
     7141 acctaccatc tcagatgata tgggcatacc aatgaatcaa gcggaatggg tagtgtccgt
     7201 ttatctgatg attgtctgtt cttgtttgtt gctgtttggt aaaattggcg atagccgtgg
     7261 gaaaatcaaa gtatttcgga ttggtacgct gatctttgtc ttgggatcgc tgttgtgtgg
     7321 gttcaatcat tcgctaggta ttttattgtt cgcacgggtg gtacaagcca ttggtgctag
     7381 tatgactatg gctacaaatg ccggaatcat cacggaagtc tttcccatac atgaacgtgg
     7441 tcgggcattg ggagcaatag gtgcgtttgt ttcattaggc tcgattgctg gaccaggtct
     7501 tggcggcttg attttgtccc aattttcttg ggcgtacatt ttttggatca atgtaccggt
     7561 gggaatcgta acgatgttga ttgctgaaaa attcttacca aaagatatca ccatgagcgg
     7621 ccatacaatc gatggagggg gctttgctgc cattgcggct acgattatca gcttttttgg
     7681 agcaatcttt ttggggcaag aaagtggctt tttccatcca gtcccccttg tactgttcgt
     7741 aatttcagtg attgcctttg tcagcttttt aaaagttgaa aagaaagcag cctctccatt
     7801 gatttctttc ggtattttta agaacaagat ttttaccatg agcttgatta cagccttgtt
     7861 gattttttct tccaacttct ttgtcaatgt agtgattcct ttttatctgc aaaatgctcg
     7921 cgggttgagt cctagctatg ctgggctgtt gatgatggtc tttcctttga tgatggtcgt
     7981 cggggcgcct ttaagcggct acctgaccga ccgggttggc ccggagattt tggtattagt
     8041 aggcttgggc ttattgtcgg taacccaggt catgtatatg tttttgtcag tggactctcc
     8101 tttgtggcta tacattgtcg ctactgccat catgggtgcc ggcaatgcct tgttccagtc
     8161 ccccaataat acgatggtta tgagctcggt cactatcgaa aacttgggac tggcaggctc
     8221 gatgaattcc tttgcccgaa atttggggat ggtcagcggg atttcgcttt ctacgacggt
     8281 cttatatcaa gcgatgtctg ctaagatggg ccagcaagta actaactata tcgcaaatcg
     8341 gccggatgtc tttttatatg gaatgaagat taccttttta ggcagctttg ttttgtgttt
     8401 tgttgccttt ttcctgacta tctggcgtat caaaaaacaa ggaggtattc agaaaaatgt
     8461 ctgaaaaaac cactgttgaa gaatttttgg aggcctgcgt atgggtgagt gggatttcca
     8521 tggatgatgg aagatgaagt gaacttctaa aagccgaaaa actcaagtat tatcttcaaa
     8581 atactagtgc tcaatgagat gcttgatttg atcacaagaa gactgcgaaa gccgctggca
     8641 accgcaagct aggtatccca ccgatggact acgttttaga ggctactggt tatgaatacg
     8701 gagccaacgc tctcatctgc ataagaatac atcacccaga ttatgtaaag attttcgata
     8761 cttctgtcaa aaaatcatta agatagataa atgatttccg tctagtcaaa ttggttcaga
     8821 atgtagacac acagatggta agaagtcact cacaattcga gaatggactt gtcctatttg
     8881 ccgtatacat cataatcgaa acgtcaacga tagtatcaat attttgacca agggctatga
     8941 atacaagcat tgccttagaa aacatcaaga accttaggaa caacggggat agcttggtta
     9001 ataagagata ccgctgttta ggcttgcaag tatactcttt tatcaagaat tccgtggctt
     9061 tagtcatgag aggcttaata ctatgaaaat tttctttagc atttttgatt taggttcctt
     9121 ttctaattat aataagatga ccactacagt aacctactga aatatataaa cagccactgt
     9181 agtaccattt tcaaagtagt ctatgagagg agaatcttca ttcttatgaa cgctggaatt
     9241 gcggatatga atttaataaa aaaaaccctt aatgatttta cttccaattc aatatcaaaa
     9301 ggtactggta tcaatttaag cacaataaaa aagctgaaaa gtggtgaaag atcagtggaa
     9361 aagctgaatc ttttagatgc tataaaaata acggaatttg ctatgaaaaa tggaaaagct
     9421 gagattgaaa tatggagata attatcgtct agtgaattac ttgccactta gctgaattta
     9481 acgatccttg gtgcttgaag ggggagattc ttgggaatag agcatacttg caagcctatg
     9541 tctttactaa caacgatatc tcttattaac caagctatcc ccgtagttct aaggctttta
     9601 cttttatcta agcaataatc gtattcaaag gaaatttttg acccttagaa agtctcattt
     9661 tatcagacgt gagcttaggc attgctgaat tttgttaatt cggttttagg ttgtgctttg
     9721 agcataatat gaaagtattc tttatcacga tttcattcat ctaaggtaat gtgatgtgat
     9781 tctgaaattc tttcaaaggc agtttttgca taagctgaca ttacatcatc aatgacatgt
     9841 ttacaatgtt tcactactaa aataaggggg taaccaagaa gaaaaactga atgattattt
     9901 gtatctaatt ccatggtata tcaaccattt cctatataga ctgattatga catggattaa
     9961 aataaaaagg cactatgtct taattgtcgg ttttcgagtt accgaatggc attcatcacc
    10021 cacctataga ggatgggcga cttctgcctg aaataagtta cactacttat aacttctaat
    10081 aaaattagat tgagtcatta ttatttaaca tcaacgattt tccagtttcc atttttttgt
    10141 aatactaatt tgtactgaaa gtagctagtg gtttttgata cattatcaag gtattttatc
    10201 tttgtactca ctagaaaatt ttttccgttt tgtagataaa ctggattctc taactccgaa
    10261 aactttaagt caatattgat tggtcgcatc gcaccatttt caacataata ctccaattct
    10321 ttttcagaag ctgatggata aagtttaaaa aatgtttcta aaaaatcggt gatttcttcc
    10381 gttgttttgg catcaatttc tgaatcgttt tctacttgtt ttgcttcata ttttgccttg
    10441 tctggctttc caatcattgt tggcaaacta gttactaaat gattcctgtt ttcatcttca
    10501 aagattgtca ctcgatatgc agaagaaatt gattgcgtct tttttccctc tgtaatatgt
    10561 tgctccacta aaaatgaaac gacaaattct tccgagtgtt tttcaacatc tagaattttt
    10621 acagattgaa cttcggaact cgtgggaata tctgctcgaa ccatatcttg gattaaagcg
    10681 agaccgtttt ctgtaaggta ctgttcgaga ttactcattc tcttttcaat tgcttctttg
    10741 ttatttttcc atgaaaaata ttctttcgca aaatcctctg taaaactttc aacgccagaa
    10801 gtattcacta ccttctcttt tataaccact ttttcatgag ttgtatgttg atcaatggcg
    10861 gtgaaatttt tataaacgcc aaaagcaaga ctacaagaca ataaaagcca aagggcaagc
    10921 accatttttc gatgcttacc cacggataca actcgttctt ttttcttttt tgggctcttt
    10981 tccttttgat tccgttcaat ttttatcttc attctttttc ctcttttctc ttatttgtat
    11041 cggccagctc cgataagatg ctgccgccaa tagttttccg ttagattcgt ccaccccact
    11101 ggatctcctg catgaaacat gcgattctcc cctgcgtaaa tgcccacatg ggtcacataa
    11161 gtaccggcat cataggttga atgaaagaaa actaaatcac ctggtttggc atcttttaga
    11221 tcaatatgag tcatggcatc atattgatcc tgagccaccc gaggaagttt caggtcaact
    11281 ttggcataac accattgggt caagccacta caatcaaacc ccgtttctgg acttgagcca
    11341 ccaaacacat aggccgttcc ttcatactta aatgcctcat caaaaatttc ttggactatt
    11401 ttgtcatcaa actgagttgt agttaggtat tgcttcacta ataaacagta aaacatattg
    11461 ccataattat accgccaccc accattttcc ttaatcgcga ttgggttggg gtaatcgact
    11521 ttttgaccac ctgatttttc ctttgaaaaa gattcagcta aagcaaaact atgcttcttc
    11581 ccgtttttcc cgacatgatc tagatacccg ccaccatagt tataggcctg aataatacta
    11641 tcttgatcac accctagttc tttggaacgc ttaaccaaag acgcaaaata gagacagcct
    11701 tgtttgatgg atgcctcggt acttaatgaa ttaggtggta atccggctga ctcagaactt
    11761 tgcataacgt cttccattgt gccaccagat tccacttgaa taatcgccaa aagaattgga
    11821 atatactctg ttatatccga ttctttggca tacttttcca ccattgcacg gtgtttcaat
    11881 acttcttctg agacactagt tccgccagga gaagtgccag aactaccatt tccctcactg
    11941 tcttcaccaa acaacaaacc cacacacatc aaaataccca taaaagagat ggtcagaaaa
    12001 gttaatgaaa taacacccac tttcttcaag ttcatttttt ctcacctgac cttgattttg
    12061 gacgatggtt cattcttttt tgtacttttt gattggtctg ctttggcaga gtggacctct
    12121 gtttcacttg ttggaaagaa tttttcttac ttgctgattg gcttttccct tttgaaatga
    12181 tttcttgact agttagtttt cgtttgattt cgggattcag atttgctctc acaatccgct
    12241 ttggtgcttc ttttttcagc atcatatctt tctgaggttg agctgcttta tctattggaa
    12301 tattcgccct tctttttccc tgacgatttg ttgcttcact cagtatcttg cgtttttcgt
    12361 ccattttcgc atttcttcgt tgtcgttgtt tttctcgcaa atccactcga tccgcttttt
    12421 cttggaacag tccgcgcttg aattcttctg gtgctttttt cgacttttcg attcctttat
    12481 ggagattgta tttcaaattc gttggcgtat tccttacctg atcctttact tgtttagtct
    12541 tatctttcac caaagcttgg gtatccaaaa ctttgccgat ttttctccca gccaaattca
    12601 ttcgggattg tttcttatta tttgaaactg gattctcctt agttaagtca gatagtattt
    12661 cgtgatcgtt cggtaatcgt gaattctttc gtagagaaga accggatggc ttaaatttgg
    12721 attttgattg ttcctttgcc aacttatttc cgactgctgc accaccacca aaagccaaag
    12781 ctcgtcccac atttcgattg agttgccgca attttcgatt cattaacatt tgcggttttc
    12841 gcatgacgcg tcttcccatt gactggctat cattactctg gaggttgaac atactcataa
    12901 tgtcgcccaa tttgaaatag ataccggcaa aggtcacaat ttgcagaaaa gcaaccatga
    12961 aaaatggata ggttgccgaa atattgaaaa acatcgtgga gatgctaaat gcagtcgtaa
    13021 tcaccaaagt aacacccgct cgcatcataa tcgtattgaa taaacgaata atcgccttct
    13081 ttcctaaact ttcataagtc ggcaacatgg acaataagaa actaattggc agaaacatcg
    13141 caaagataat gaagagaatt tgcgagaaca acataatccc tgttagaaga aaaacaaaga
    13201 aggaaatgcc aatattgaac aataccaaaa agaccacggt ccctaaacgg ttcatggtct
    13261 tggtaatact gagattcgca ttgtcattgt cttcaatctc tgccttgacc gcttcttccc
    13321 gatctttgcc tttgttttca tctggactca cagatagaat cttgttgacc cggtcttcac
    13381 caatttcttc tatgttggaa tcatcaaatt gcagtagtaa ccaaggttgt tggacttgaa
    13441 tcgaaaacaa actatcccga atcaaatcca cactatcttt tccttggctt tctgaattgg
    13501 gtacaacgat ctcggttcca agggtaaggg ccgcttcact aacatctgag ctaaagtcat
    13561 tgatttttgt gatataggta ggcgcataag caatgaacga acccgatagt agaaaaatca
    13621 tcacaaaatt aatcacggct cgaactgctt tcgtggtttc tcgttttaat aatccggtat
    13681 acgccacata cacccccaga gctaaaatca tcaataatag aaacccaaaa taaaatccgg
    13741 aggtctggag tccattttca gtaataccag ccaatgtttg gatattcttt ccaatacttt
    13801 cagccgtatc cgaaatgaaa tctaatttgt aagcctcttg aaccacataa cccgtggcgt
    13861 tcgacaaata caaactcacc gtccaaatga aattagtaat ggcataaaga ccatacatca
    13921 cgcttttccc taagccatca ccccaattcc aaggcaacca atcccaagag ctatccacaa
    13981 agaaatctag ttgatagttg ttcagtgaat atttggaata tagatttcct gcttcaactg
    14041 tatcatcaac tagccctgtc gcctcggcta ccgtaccaac taaactcaat agaactatca
    14101 gagtgagtat gctaataaaa acgattccca caatccgaaa aagtttcttt ttcatcccct
    14161 cactccattc tctcttgaac aggtggacgg gtatcaaagg catggaagag ttcttcaaag
    14221 actggatgta cctgaaccac gcctacccga ccatacaaat cctgcatcaa gcattggcca
    14281 ttttccaaat ctcgtaggcg tttttgattg ctttcatctt ctcgatccaa gccaaagaat
    14341 tccaaggttt tcttgatttc atgaatatcg gtactgcgaa acgcaaactt caacccgata
    14401 ttattcttca agcgttcatc cagtaaatca tcactatttt gcgtgacaaa gtaaaccccg
    14461 gcattcatag cccgcccagc acgaacgagc ttattcgata atgttttccc ttgcgctact
    14521 tgaagaaaac tccacgcctc atctaagtct acaattttga agatttctcg attactatgg
    14581 ataaagtcca aggcaaaagt ggaaatgacg attagcatgg aaacactaag caattccatg
    14641 gtggtatatt cttcaaaagt ggtttctgca tctggtaaaa ccaaatccgc tacttgaatg
    14701 atatttaact gcctatctaa actaatcgac tgggtaatcg aaccatctga gaaaagcaaa
    14761 tgggcaaaat cataatcggt aaaggactcg atgtgatccg cgatattttc cgcaactggt
    14821 gagccttctt ttcgaagctc attaattact tgtaataatc cccgttgatt gctttgggta
    14881 accgtccgaa tggccttacg caacactgga aacttctccc catctcgact agaaattcct
    14941 gttaaaaagg tcagaatatc aattgctaga ctttcagaat ccttcttttt ctccataatc
    15001 acataaggat caagtaatcc ttgatttttt ggcttactag ttaagttgag aatattgatt
    15061 tcatccgcaa tttctggcaa ggtttctttc cagccacccc gttccccttt tggatcgaca
    15121 atcacagctt gtccaccaaa aaggacggcg taataaacta agagattgtt actaaaggac
    15181 tttccgccac cgagtgaacc gaggaatgcc gctgctagcg cattggtaac tgaatccttg
    15241 accccttgtg aggccaatgc cggtttcagg taaacattgc gccccgtatc tacgttataa
    15301 ccaaagtaaa tgccttccaa ctcccctaac atctgagtgg cgccaaaacc aagtccggcg
    15361 agaaaatcag acgtaacata ctggatataa tcattcatgt atcgcttact agaaggtaag
    15421 aattcttcat gtagccccat catatcgcca aaaggccgga ctagttttac attggtatca
    15481 tcataaaaat ctagcacttc atcacaccgg cgctttagtt catctactga ttcggcactt
    15541 actcgaacca catagctcag tttgtacatg gattctttgg actgatccaa ggtagtttcc
    15601 aattcatcta cggaatccaa tgcatctaag acattggaat ttgtttcatt gtcagattga
    15661 taggcatggt tgtccaagtc ttttaattcc tttttcttat tgcgaacggt agcaagtgcc
    15721 tttttgttcg tcacaatctc cacattcata ctagtgtcaa ttgggaatgt aaattgttgt
    15781 tgctggtaat agaaaagttc tgaggaggga aactccattt cccccacaat tgtattaatt
    15841 gttaagtacg ctacatatga ttcatgattc tcatgttcca tgcataagta ccggggcttt
    15901 tcttcaatca aacaacgact gggacgtaat aagtcgtaac gtttcaccaa agtttccgac
    15961 ttcagctttt tctttggtag ctgaaattca tattcttcaa atggtgtacc cttttcgcca
    16021 tagatatgtt caatcaaata catcagatca ctcggtgtga ctcgtctgac tttaaatctt
    16081 cgagccaatt tactttccat tagtttttca agcttggtat atcggcgaat ttcttcattg
    16141 gataaggaaa caaaatcgcc catcaaatga tgattcactc catagacaaa ttcttgaaag
    16201 ccggagaaga aagatttctt gagattcttt agattgacct cttcatctgt cgcaatcagt
    16261 ttgaagccaa taaaaaagcg ataatcaatc tgactatcgc caatcatgga tactaatgcc
    16321 tctgtctgta aatcaattcg ttgtttcgct acttctgtta atcgcccggt aatttccttt
    16381 tttgatcgtt cttgcgtggc acgaatacta ctttctgtgg caatttgtaa ggcatgaatc
    16441 ttgccttcac gattttgcgc aatcaattga cgaaagttat cgtggacttg atatttctgt
    16501 tcaggtgaca aaaaggagta attgtaaggt attaactcat agtaggcaaa acattctccc
    16561 tcttgattaa agacaagatt attttcaata tacttaatcg ggtacatagt tcacactcct
    16621 taccagagta atgggttcgt cccatcgttt cttctgttct ttgactttct ttcctgcgaa
    16681 agtgacctta aatcgtaagt gatagctaat aaaagatcgt aaaaatccca atggtttctt
    16741 accgtcaaac gttttttgcg acatgaacca agtaactgcc accggtatac ctaagtattt
    16801 taaaaaggcc ccctctatca tagatagtgg aggcacatgg gcaaatacga tgacaaacag
    16861 caaggataaa acaaaccaag ccatctggtt aaaagtcaca ggaaaaggca gttgaaagtc
    16921 attaattgca taaatgacct tttcaactgc ccaaatactg gtgtagcttt ttattttctt
    16981 catcaaatca ttcctttaaa aagaaggata gtttagaaat caactaccct tcaataattt
    17041 tgttaatatg gatactcaaa aacacctcga ctcgttacca aataattgcc tccaatctcc
    17101 aagtctctac cacacgcatc aaaatcaata tacgtcttca agtgttctgg tacttctcca
    17161 aaatcaccag cttctacaat caagaaatat gctacatcac tcatatcatc gcaatctgga
    17221 taatagataa tatcatccac atgctctacc atctcctcaa aagaattgaa gaaagcatgt
    17281 tgaatctcag aagcaacttc accaactggc gttccttcaa gttcctccgc taagccacac
    17341 aaccgattaa tttcctcaat tggcgtatac tcatcaatct caaagggaag ttcataatca
    17401 tgaattgcat attcctcgta ttcgtcattt aacccaattc gttctttcac ttcatcaaaa
    17461 tcgacaggtg gggtaaacca cgcccccacc aattcacctt cgttatattt cccgaggttc
    17521 gcaatataaa cacgcatctg ttccatcgtg cttccccctt acgcaccgac aattcggtta
    17581 aacaaactga gtaagacatc cttcacccca gaagcattaa agaccaatcc gaccgcaatc
    17641 aaagcaatca ccaaaaagcc aatcagtttg gaaaactccc gcttaaatcc taaaaacaaa
    17701 ccaatgacca caattgccag taagactaag gattgggcat tggttaaaaa ccatt
//
LOCUS       DAPBCF010000052        17740 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.053, whole genome shotgun sequence.
ACCESSION   DAPBCF010000052 DAPBCF010000000
VERSION     DAPBCF010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.053"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..1030)
                     /locus_tag="RD508_002194"
     CDS             complement(<1..1030)
                     /locus_tag="RD508_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7736738.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="RD508_002195"
     CDS             complement(1112..1801)
                     /locus_tag="RD508_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDT7736739.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="RD508_002196"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="RD508_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDT7736740.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="RD508_002197"
     CDS             complement(2328..2831)
                     /locus_tag="RD508_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDT7736741.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="RD508_002198"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="RD508_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDT7736742.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="RD508_002199"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="RD508_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDT7736743.1"
                     /translation="MAKKVEKIVKLQIPAGKATPASPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="RD508_002200"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="RD508_002200"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HDT7736744.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="RD508_002201"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="RD508_002201"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HDT7736745.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="RD508_002202"
     CDS             complement(6443..7462)
                     /locus_tag="RD508_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDT7736746.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="RD508_002203"
     CDS             complement(7635..8540)
                     /locus_tag="RD508_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDT7736747.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="RD508_002204"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="RD508_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HDT7736748.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="RD508_002205"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="RD508_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDT7736749.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="RD508_002206"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="RD508_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDT7736750.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="RD508_002207"
     CDS             9753..10397
                     /locus_tag="RD508_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7736751.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="RD508_002208"
     CDS             complement(10453..10956)
                     /locus_tag="RD508_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDT7736752.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="RD508_002209"
     CDS             11553..12518
                     /locus_tag="RD508_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HDT7736753.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="RD508_002210"
     CDS             complement(12617..13789)
                     /locus_tag="RD508_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7736754.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="RD508_002211"
     CDS             complement(13776..14921)
                     /locus_tag="RD508_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7736755.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="RD508_002212"
     CDS             complement(14935..15867)
                     /locus_tag="RD508_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7736756.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="RD508_002213"
     CDS             15984..17063
                     /locus_tag="RD508_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDT7736757.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="RD508_002214"
     CDS             17060..17689
                     /locus_tag="RD508_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7736758.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
BASE COUNT         5332 a         3698 c         3191 g         5519 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tgaagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg
//
LOCUS       DAPBCF010000053        17538 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.054, whole genome shotgun sequence.
ACCESSION   DAPBCF010000053 DAPBCF010000000
VERSION     DAPBCF010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.054"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(37..846)
                     /locus_tag="RD508_002215"
     CDS             complement(37..846)
                     /locus_tag="RD508_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7736759.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            1139..2575
                     /locus_tag="RD508_002216"
     CDS             1139..2575
                     /locus_tag="RD508_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDT7736760.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            2745..3941
                     /locus_tag="RD508_002217"
     CDS             2745..3941
                     /locus_tag="RD508_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDT7736761.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(4003..4188)
                     /locus_tag="RD508_002218"
     CDS             complement(4003..4188)
                     /locus_tag="RD508_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HDT7736762.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            4419..7733
                     /gene="dnaE"
                     /locus_tag="RD508_002219"
     CDS             4419..7733
                     /gene="dnaE"
                     /locus_tag="RD508_002219"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDT7736763.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLGPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            7901..8863
                     /gene="pfkA"
                     /locus_tag="RD508_002220"
     CDS             7901..8863
                     /gene="pfkA"
                     /locus_tag="RD508_002220"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDT7736764.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            8937..10721
                     /gene="pyk"
                     /locus_tag="RD508_002221"
     CDS             8937..10721
                     /gene="pyk"
                     /locus_tag="RD508_002221"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDT7736765.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(10756..11658)
                     /locus_tag="RD508_002222"
     CDS             complement(10756..11658)
                     /locus_tag="RD508_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7736766.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            11844..12413
                     /locus_tag="RD508_002223"
     CDS             11844..12413
                     /locus_tag="RD508_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HDT7736767.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            12471..12650
                     /gene="rpmF"
                     /locus_tag="RD508_002224"
     CDS             12471..12650
                     /gene="rpmF"
                     /locus_tag="RD508_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDT7736768.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            12820..14241
                     /gene="gndA"
                     /locus_tag="RD508_002225"
     CDS             12820..14241
                     /gene="gndA"
                     /locus_tag="RD508_002225"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HDT7736769.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDEAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            14434..15120
                     /locus_tag="RD508_002226"
     CDS             14434..15120
                     /locus_tag="RD508_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7736770.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            15117..16622
                     /locus_tag="RD508_002227"
     CDS             15117..16622
                     /locus_tag="RD508_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7736771.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            17309..>17538
                     /locus_tag="RD508_002228"
     rRNA            17309..>17538
                     /locus_tag="RD508_002228"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT         5672 a         3060 c         3681 g         5125 t
ORIGIN      
        1 tgtcacaacc tcttttttgt ggaatctaat tctctattat agtttaagta gtttttccag
       61 ataaacagct aaaccgtctt cctgattgct caaaggagtg acatcatttg caatgccttt
      121 gagttggtca gtaccgttag ccatagctac tccccaacct gcataatcca acaattccaa
      181 atcattatgc tcgtcaccaa aggcaatgac gtctttttga tcgatagaca ggtagttagc
      241 aatctcttgc acgccttttg ctttttggat tccttttgaa acaatctcta agatggcagt
      301 aggtccaccc catgtccgaa catcgacata actgccaaat tgacgtgtta attcagcaga
      361 tacagctcct gcaaaacgtt tgtctgttcg gacaagcaaa gatgtaggat ttgtcgtcaa
      421 atttttagga gaaagcaaat tcttctctcc tggacgagaa gaagcaaaaa ttttttcatc
      481 aaagaaatca aaactgtcaa taaaaaaagt atcacgattt tcagcagcga taaaatctaa
      541 atttagctgc tttttttgcg ataagatttc aaaagcgatt tcacgattga tcaacgtttc
      601 tctttcacca tcccagtgct gattagggat gtgtactaat gcgccgttaa aattaaccat
      661 cggtgttgtt aattctaatt gttggtaaaa ctgatggctc attcggaatg ggcgtcctgt
      721 agcaatactg acatgatgac cggcattgat tgcttttttt agagtctctt ttgttttaga
      781 tgtaatcatc gaatcttgat tgagggtagt tccgtccaga tcgatggcaa ttaatttttt
      841 attcaataag ggtccttcct tcctcaacta gcatttgttt tagtctagca tattttaggt
      901 aattaacaag agcaatcagc tattcctaac aaaaactaca gttatggcta tataaatagc
      961 taaacataag ctaaacacga acgttaagta ttattttcgc tttttttgtt aaaaaaacgt
     1021 tgaaaagcga atgaaacgtc tatataattt gaaattgttc gatggatttg ccctatttta
     1081 cttatttttt attattatag ttttccatca gaaaaaaatt cagggagtgg aactttttat
     1141 ggaaaagttt ttcggtttaa agaaaaacaa tacaaatgta tcaactgaaa taatggcggg
     1201 agtaacgaca ttctttgcca tgagttatat cttattcgta aatccgacga ttttgtcagc
     1261 atcaggtatg cccttccaag cagtatttct agcgacaatc attgcatcga ttattggtac
     1321 gctggtaatg ggattgttcg caaatgtacc atatgctcag gcacctggta tgggattgaa
     1381 cgcatttttc acttttacgg tcgtttttgg gcttggttat tcttggcaac aagccttggc
     1441 aatggtgttt atttgcggat taatcaatat ttttattact gtcacaaata ttcgaaaaat
     1501 gattattcgg gcgattcccg aaagtcttca acatgcgatt ggtggcggga tcggtatttt
     1561 cgttgcgtat gtcggaatca aaaatgcagg attcttatct ttttcagcag accagtcagc
     1621 tatttcgagc tctgtcgttg aaggcggaaa agcgacaaat gttacgataa atggtggaat
     1681 cgtccctgcg ttagccaact ttgacaacgc tcctatctta ttggctgtga ttggtttggt
     1741 actgacagcc attttagttg taaaaaatgt ccgtggggct attcttatcg gtatcgtagc
     1801 gaccacagtc cttggtattt ttatgggtgt tgttgattta agttccattg attggcaaac
     1861 gaattcgtta ggtaattcat ttaaagaatt aggaacaact ttcggtgcag catttggttc
     1921 tgaaggcatg caatctttat tcagtgattc ttccaagatt cctcaagtat tgatgacgat
     1981 catcgcattc agtttatctg atactttcga tacgatcgga acatttatcg gtacaggacg
     2041 ccgcacaggt attttctcaa aagaagacga gatcgcgttg gaagatggtc gtgggttcaa
     2101 aacaaaaatg gataaagcac tatttgccga tgcgatcgct acttctgtgg gggctatctt
     2161 tggtacatcg aatacaacaa cttatgtcga atctgcagct gggatcgggg ccggtggacg
     2221 tactggtttg acttcagtag tagtggcagt gctattcgca ttaagtagtt tattctctcc
     2281 actgatcgcc attgtaccaa atcaagcaac tgcgccagca ttgattttag ttggagtaat
     2341 gatgatggct tcttttgcag acatcaaatg gctagatatg gaagaagctt taccggcctt
     2401 ctttgcatcg atctttatgg gattgtgcta tagcatttcc tatgggattg cagcaggatt
     2461 tattttctat acaattgtga aagtaatcaa aggaaaatac aatcaagttt ctgttgcttt
     2521 gtggatcgtt gatattttat tcattatcaa cttcatcatt ctagcaacaa tttaactaaa
     2581 gagaagggat tggaacagta tttgttctga tctctttttg ttttacataa aaagaacgtt
     2641 acatataaaa tgacctttgc gggatttttc tctttttact ggcgagatcg ttgcttgttt
     2701 attcgaaaat aggtatgata aaagagacga aagagggatg atagatggag attaattgga
     2761 gaaaaaattt agtgattgcg tggattggct gttttttcac tggtgcaagt attagtttag
     2821 ttatgccatt cataccagtt tatgttgagc aactaggaac accaaaagat caaatcgaat
     2881 tgttttcggg actagcaatc tctgtgactg cttttgcatc tgccgtggtt gcaccaatct
     2941 ggggaaatct agctgatcga aaaggccgaa aactcatgat gatccgtgca gcagcaggga
     3001 tgacattaac aatgggatct ttggcttttg taccaaacgc gtattggctt ttgatcatgc
     3061 ggttttggaa tgggattttg tctggatata ttccaaatgc cacagcgatg attgcttcac
     3121 aggcacctag agaaaagagc ggatgggcgt taggaacatt gtctaccgga gcgattgctg
     3181 gaaatctgat cggaccttca atgggcggtg cactggctca gtggtttggt atggaaaatg
     3241 tattcttgat cacaggggct ttgttgatga tcacaacggt attgaccatt ttcttagtca
     3301 aagaagattt ccatccaatc gagaaaaaag atctgataag caccaaagaa attttttcaa
     3361 aaatggatca tctctctatt ttgatcggtc tcttcattac gaccttgatt ttacagatag
     3421 gaatcactac gatcagccct attttgacct tatatattcg tgaattgagc ggaagtacag
     3481 aaaatatcct ttttgtcagc ggcttgattg tttcgatagc tggtgtttcc gctgtctttt
     3541 cttcaccgaa actaggaaaa ctaggggata agattgggaa tcaaaaagtt ctaattggag
     3601 gactcatttt atcattttgc tgttatttac ctatggcatt cgtcactaca ccgctccaat
     3661 taggtatact tcgctttatt ttaggctttt caactggcgc tttgatgcct tctgtcaata
     3721 cactgatcag taagattacg cctcaagaag gagtcagccg aatctatagc tacaatcaga
     3781 tgtttagcaa ctttggacaa gttttaggtc ccatgctagg atcgacagtc gcgcatgctt
     3841 ataattacag tgctgttttt attgtgacaa gtttgtttgt tctgtcaaat attcttcttt
     3901 ctttattcaa ctttcgtaaa gttcttcgca gcagattata atggtggtga ggagtagaaa
     3961 ataaaaaaga gcttgagaaa tctcaagctc ttggctgttt ttttacgaat gggcagaggt
     4021 ttcttttctt ggcgcaactg caccaatcaa aaggataatg acacccgcaa tgaatgaaat
     4081 gattgttgtc aaagtaaaat catatgttcc gcttgttaat gcagcaccaa tataaccgac
     4141 tacttgacct agaacgacag cccagaataa tgtaacgata tatcgcataa agaacacctc
     4201 ttttctatct taattttacc agattttctt tgaatgtaaa gaaacgagac caaatctcaa
     4261 taaaatttga gttcttgcga aagaactcat tcctacagat tacaagcaag caaatgaagt
     4321 ggaataatca acttcagcgc ctgctatctt aatgaaagta aaaggatcaa accttttaac
     4381 gctagtgaat tttaacgaaa aaaaaggcgg aatgcaagat gtttttccca caactttata
     4441 caattacttc ttattctctt ttacaaagta cgatacgtat tcgagaatat gtacaagaag
     4501 caaaaaaaca aggctacact tcattagcca taacggataa agatgtctta tacggtgcac
     4561 ctgaattcta tcgtatttgt gtagaagaag gagtacagcc aatcattgga ttacatctta
     4621 gttatactta tgaagaaaaa aattatggct tgcttgcgta cgcaaaagat gaaataggtt
     4681 atcagcagct gatgaaactt tccagccgaa aaatgatcca agaaaaattg gaacttgcag
     4741 aaatgacaga aaccgaccat ctagcgtttg ttgttccggc aaatcattct gtttctgagg
     4801 ctttcaataa agaggataac tttttcggtc attggcagtt tttacttgaa aatgttttta
     4861 ctagaaattt ttatatcggc ttgacagaaa acacgcctga tcaattgcct gaatggtatc
     4921 agtatgtgat aaaagaaaat tattcgcttt gtgcattaca tcccatcgct agtttacaac
     4981 aagaagaact ttttgcactt gaagtgatga aacatatcaa agagggaagc caaatacctt
     5041 tagaaaattt atctgcatct ttaccactaa cagcaaatgt ctatcttctt tcagaacaag
     5101 aaatgatcaa acgattcgaa aaagcgggtc tttcccaagc tgtaataggc gcccagcgtt
     5161 tagctgaatc gatttcattt gaattccagt tccatcagaa attacttccg cattatccag
     5221 ttcctaatgg aaaacaagct ggagaatatt taagagagtt atgctattcg caagtggaac
     5281 gccgaatcac tgactataca aaggaatacc aagaacgttt ggactacgag ttatctgtca
     5341 tccatcaaat gggattcgat gattatttct tgatcgtatg ggatgtaatg gcttttgctc
     5401 atagaaacaa aatcgttacc ggtgcaggtc gtggttctgc tgcgggttca ttagtagcct
     5461 atgtgttaga aatcacagat gtggatccat tagaatatga tttgctgttc gaacgctttt
     5521 taaaccccga acgctttacg atgccagata tcgatttgga tattcctgac aatcgacgtg
     5581 aagaagtatt gaattatgtt cgagaaaagt atggacaata tcatatggca caaatcgcaa
     5641 catttggcac aatggcagca aaaatggttc ttagagatgc agctagagtg tttggtttat
     5701 cgcaaagtga agcaaaccgc tggtcaaaag caatacccaa tcaattgaaa atcacattga
     5761 cccaagctta taaaacttcg catcaattag tagaattagt tcaggcaagc gaaaaaaacc
     5821 aacttttatt caaaactgca gtgattttag aaggattgcc aagacatgtt tcgactcacg
     5881 cagcaggtgt agttatcagc gataagaatc tacttgaact agttccgctc caacgcggtt
     5941 ctgatgaagc ttttctgacc cagtatacga tgaatgaggt agaagcaatc ggtcttttga
     6001 aaatggactt tttaggacta cgcaacttat cgattattga ttttactttg aaagctgtta
     6061 agcgagtaga agggtatgag atccgattaa aagagatccc gctaaatgat gcaaaaacgc
     6121 tgctcttgtt tcaacgaggc gaaacctcag gagtatttca atttgaatct gctggtatcc
     6181 ggaacgtttt acgaagatta ggtccagaaa acatcgaaga tattgccgca gtcaatgcat
     6241 tgtatcgacc aggccctatg caaaatatag ataccttcat tgccaggaag aaaggaaaag
     6301 aagccattcg ctacccagat gattcactga tcccgatttt gaaaaacaca tatggagtga
     6361 tcgtctatca ggaacaaatc atgcagatcg cctcgactat ggctggattt acattagggc
     6421 agtcagatat tctgcgacgg gcagtgagta aaaagaaaaa agacgtatta gatgaagaaa
     6481 agtcgcattt tgtatcagga gcattacaac agggatattc ggaaaaaaca gcagcgaccg
     6541 tatatgaata tatcgaaaaa tttgcaaact atggattcaa tcggtcacat gcatttgctt
     6601 attcattcgt gggattccaa atggcgtatc taaaagccca tcatccaggt gctttcttta
     6661 ccagcctgat gaattctgtt cggcataaca catcaaaatt gaaagaatat attgcagaag
     6721 cacgtaaaaa taaactcaaa ctttcctcgc cgtccattaa tcaaagtaat tccagttttg
     6781 agttggtcaa taaggaagaa atcagattcg gactgacagc gataaaaggt attcggcgtg
     6841 attttgtaga agatatatta aacgaaagaa aacaaaatgg cccgttccag tcagtggatc
     6901 aattcctcat acggatcgat aagcgttggc tgaaattaga gttactgcaa tcactgacag
     6961 cagtaggcgt ttttgatgaa ttatctccta acaggaaaca attgatgctt gatctcgaag
     7021 gaaaaatcca aaatatcgtt tacagtggtg gaagtcttga cttgctggga atcatggcat
     7081 taaaagaaga agaagtcgct gactatacac tagaagaacg cttgaagctg gaagaggagt
     7141 acttaggtat ttatttgtca ggtcatcctg cagaagggtt tgatcgtctt cgtttagcta
     7201 aacaagttca gctgattaca gatatcgtcc ctaatcaacc agtcaattta ttagtgatga
     7261 tcaaggaagt tagagaaatt cggacaaaaa aaggagaact gatggccttt gttgaaggaa
     7321 ccgacagtag tggagaaatt tctgtcacag tttttccaac tctttatcgt aaatatcgta
     7381 atttgtttgc cgttgatcga gtgatctttg ttcaagggcg gagcgaaatc agcaaatata
     7441 atcaggaact gcaactaatt ggagaaagct ttgctgatcc taaccagtta gaagcccagt
     7501 atccttcaca aacttgctat ttgcgtatta cagaagaacg ggaagatccc gagataatga
     7561 aacaattaca agtgattttt cagaaacacc caggatatat accagtagtt atgtatcacg
     7621 aaaaaacgca acgaaaagta gttctgtcag atgcttattg ggtggatgac agcaagagta
     7681 taaaggggca acttatttat ctgcttggcg aagataatgt ggttttcaaa taacttacgg
     7741 taaaaaatac tacttgcttt catttttttt cattttttta tccgtaaatc aagacaagtg
     7801 agaaaaataa tgttagaatg ttagtcgtgg ttaacgcaaa aatggttgta aacctaagtc
     7861 atacttagga taaagtattt taatgaggtg aatgtttatt atgaaacgca tcggaatttt
     7921 gaccagtggc ggagacgcac ctggaatgaa tgcagctgtt cgtgccgttg ttcgtaaagg
     7981 tatttacgaa ggactggaag tatacgggat caattatggt tttgccggtt tagttgctgg
     8041 agatattcgt cgtcttgatg tggcagatgt aggtgacaag atccaacgtg gtggtacatt
     8101 cttgtattct gcacgttatc cagaatttgc aactgaagaa ggtcaattaa aaggaatcga
     8161 acaattgaaa aaattcggaa tcgaaggtct agtggttatc ggaggagacg gctcttatca
     8221 tggcgcaatg gctttgacaa aacgcggttt cccagcagta ggtattcctg gaacaatcga
     8281 taatgatatt cctgggactg atttcacaat cggttttgat acagcaatca atacagtact
     8341 agaatcaatt gaccgtattc gtgacacagc gacttctcat gttcgtacat tcgttatcga
     8401 agtaatggga cgcaatgcag gagacatcgc tttatggtca ggtgtggctg gcggagcgga
     8461 tgaaatcatc atcccagaac atgattttga tatggcttca gttgctaaaa aaatccaaga
     8521 aggccgcgat cgcgggaaga aacattgctt gatcatcttg gctgaaggtg taatgggcgg
     8581 aaatgaattc gctgagaaac tttcagaatt tggcgactat catacacgtg tatctatctt
     8641 gggacacgtt gtccgtggtg gagcaccaag cgcacgcgac cgcgtgttgg caagtaaatt
     8701 cggtgcttac gctgtcgaat tgcttcaaga aggaaaaggt ggattatgtg tcggtatcca
     8761 tgacaacgaa atcgttgcgt ctgacatcat tgatacactt gaaaacaaca aacataaacc
     8821 agacttatca ctatatgatc taaataattc actttcattt taagagtgaa agaaaccaag
     8881 ctatttaagc tgtgtacagc tttaaataaa caaaattgaa tgggagagtt ttttaaatga
     8941 aaaaaaccaa aatcgttagt acattaggac cagcaagtaa ctcagtagaa attatttctc
     9001 aattgattga atctggggca aatgtcttcc gctttaactt ttctcatggt gaccatgaag
     9061 aacaattatc acgtatgact atggtccgtg aagcagttaa aaagacagga aaagatgtcg
     9121 gtattctttt agatacaaaa ggagctgaaa tccgtacaac tgttcaaggc acaacagaag
     9181 ctgattttgg tcgtgcagga tacatcaaat ttgaagtagg agatcaaaca cgcatctcta
     9241 tggatcctga acatgtaggt tcaaaagaaa aaatcgcggt tacttaccca ggattatttg
     9301 acgatgttca cgttggcgga cacattttat ttgatgatgg tttgatcgat atgcaaatca
     9361 ttgaaaaaga cgaagcaaac cgtgaattag tcgtagaagt taaaaatgca ggtatgctag
     9421 gatcacgtaa aggggtaaat gcaccaggcg tttctattag tttgccaggt attactccaa
     9481 aagatgctga cgatattcgt tttggtttag acaacgatat cgactttatc gctgcaagtt
     9541 ttgtacgtaa agcacaagac gttctagata tccgcgaaat cttagaagaa aaagacatga
     9601 ctcatgttca aatcttccct aaaatcgaat ctcaagaagg tatcgacaac attgacgaaa
     9661 tcatcaaagt ttctgacggt gttatgattg cccgcggaga tatgggtgtt gaaatcccag
     9721 ctgaactagt accaatggtt caaaaacgca tcatcaaaaa atgtaatgct gctggtatcc
     9781 cagttatcac tgctacacaa atgttagaat caatgcaaga aaacccacgt ccaacacgtg
     9841 cggaagcttc tgacgttgct aacgctgtat ttgatggcac agatgcaaca atgctatctg
     9901 gtgaatctgc aaacggggac tacccagttg aagctgtttc aacaatggca cgtatcgacc
     9961 aagaagctga aaatgcatta tcagaattag gtacattcca attgaacgaa ttcgataaaa
    10021 cagatgtaac tgaaacaatc ggtttatctg tagctcgtgc tgcaaaaaat ctaggcgtga
    10081 aaacaatcgt tgctgcaact gaatcaggat acactgcaaa aatgatttca aaatatcgtc
    10141 cagatgcaga tatcttggct gttacttttg acgaacgcac aaaacgtggt ttgatgttaa
    10201 actggggcgt ttacccaaca gttgctgaaa aaccatcaac aactgatgaa atgtttgaac
    10261 tagcagctaa aaaagctgtt gaattaggtt tcgcatcaga aggcgattta atcttgatca
    10321 ctgctggtgt accagttggt gaacgcggaa caactaacgt gatgaaaatt caaatgattg
    10381 gttctaaatt attagaagct caaggcgttg gacaaaaatc tgtcgttgca aatgcagtta
    10441 ttgcttcatc tgctgaagaa gctgtaaaaa aagcaaaaga cggaatggtt ctagttgtac
    10501 catcaactga caaagaatat atgcctgcaa tcgaaaaagc agctgctgtt atcgttgaag
    10561 aaggcggatt gacttctcac gctgcagttg taggaattgc acaagatatt cctgtaatcg
    10621 ttggtgctaa aggcgcaaca acaacaatta cagaaggtga attgattacc gttgattcac
    10681 gtcgcggcat cgtttaccgt ggcgaaacaa cagctatcta atttagctta ataaaaaata
    10741 aaaacagctc ttcttttacg aagagctgtt tttttgtgct gtaacgaatt catggataac
    10801 ttggactact tgttcttgaa gaggcgtgac gatctgctgt gttcgttttg ccaatgaaat
    10861 caagaagcga ggctgaactt catctgaaag agggaggcaa actaaatgat cttcaggatg
    10921 gacagcaatc tctgccaaaa aaccgatacc cacattttct cggaccatac tctttaaaat
    10981 cgtcaagtca ttgctttgat aaacaacttt tggatgagta tgtgtttgtt tagaaagctt
    11041 agtgaatgct gcggggtgga cataatgttc gttcaatagt acaaactgtt catctgctat
    11101 atctttgaaa gagacagtat cctgcttgga aagaggatgt gtaggtggca cgacgatcat
    11161 gaaacgtttg tccaaaagta actctgtttc taaatattga tccacgattg gctgtgttga
    11221 gcctaataca gctaaatcga tcctcccttg tcggatcatc ccgtataagt cccgagagcc
    11281 tccatcggta atctcaattt gattcatcaa ttcatgcttg ataaagtaac ttgacagttt
    11341 aggaaagtat tcattgccga taataggagg catgccaaaa cgaagctttt tcttttgcaa
    11401 ctgagtgatt tcagctcttg cagtagaaat ctcttggaga atggtttgtg catggagaaa
    11461 cagctgcttt ccagaaggcg tgacgattaa ttcgtgatgc gatcgatctc ttgtaataag
    11521 tacggtgtca aactcttttt caagacgttg taatgcatat gtaatagtag gttggctcac
    11581 acggaaataa ttagccactt tcgtaaaatt tttttgtttg acgatttgga catagtattc
    11641 gatatctttc gtgttcatga agatcatccg ctcctttaat ggaataatga ttattgtaaa
    11701 tgattctgag gatgatagca aacagaggct ttctaataaa gatttttctg tttttttatg
    11761 aactgcaagg tgtcaagaaa atttcattga caacatgctt tttgccctgt ataattgctt
    11821 ttgttgctta ggagtgatga aaaatgaaat ggtctttatt ggaattgaga aaataccagg
    11881 agacaccgtt aacttttcat gagacgctcg acttgaaagc cgctctcatg aagcgagaca
    11941 atttaatact tgatgttgcg ccagtggaag tcgaaggttt ggtctcagtt gataagaaag
    12001 gctatatcgt tcattacact gtgcagacga ctttgacagt tccttcaaca cgttcactag
    12061 aacctgttga actgcccatg gatttttctg tagacgaagt attcatgaca gaagaacaat
    12121 tccaaagtag agatgaacaa atgtctgcgg atgagatttt gctaattgaa ggtccattat
    12181 tgaatttagc agagtcgatt gaagacaaca tcttattggc gattccaatg cgggtattga
    12241 caaaagaaga ggaagcagca acagaacttc caaaaggcaa tgattgggaa gttgtttccg
    12301 aagaagaata ccagcgcaga aaaatggaag aagccgagaa taaaattgat cctcgtcttg
    12361 caaaactatc tgaacttttt gattctaaat caaaagacga cgataacaag taagattgga
    12421 atatattgtg tctaatttag atacaagact ttacaaggag gtgtagcaaa atggcagtac
    12481 cagctagaag aacatcaaaa gctaaaaaag caaaacgtcg tacacactac aaattgacaa
    12541 tcaaagggtt aaacgaatgt ccaaactgtg gtgaaatgaa aaaaagccat cacgtatgtg
    12601 caaattgtgg ttactatgat ggtaaggacg taatgtcaaa agaagcttaa tacattttaa
    12661 ttagaaaatg taaaacctca aggctaacca tggagccttg aggtttattt ttttgtagtc
    12721 ggtaaataaa aaatatgttg ttctttagtt tgcaatgtag ccgtgttaag ctataatgta
    12781 agagattagg gagaaatccc gtatgtagga ggagttcata tgtcaaaaca acaaatcggc
    12841 gttgtcggta tggccgttat gggtaaaaat ctagccttga acatagaaag ccgcggctat
    12901 tcagtggctt tattcaatcg tacaggggct aaaacaaccg ctgtagtaga agaacaccca
    12961 gataaaaatt tcaaagcaac atatacaatc gaagaatttg tagaatctat cgagaaacca
    13021 cgtcggatct tgctaatggt caaagcagga ccggcaacag atgcaacgat ccaagagttg
    13081 cttcctcacc ttgataaagg cgatattttg attgacggag gaaatacatt ctttaaagat
    13141 acgatgcgtc gtaatgaaga gttagccaac tctggcatca actttatcgg tacaggcgtt
    13201 tccggtggtg aagaaggagc tttaaaagga ccttcaatca tgcctggtgg acaaaaagaa
    13261 gcctatgcgc tagttgcacc aatcttagag caaatttctg caaaagcaga agacgaagca
    13321 ccatgtgtca catatattgg cccaaatgga gccggacatt atgtgaaaat ggtacacaac
    13381 ggtattgagt atggagatat gcaactgatt gctgaatctt atgacttaat gaagaatatt
    13441 ttaaaccttt cagtagaaga aatggctgat atctttaaag aatggaatca aggcgaatta
    13501 gacagctatt tgatagaaat cactgctgac attctgacac gtaaagacga tgaaggaaca
    13561 ggtaaaccag tagtagatgt gatccttgat gcagctggga ataaaggaac aggtaaatgg
    13621 acaagccaaa gcgcgcttga cttaggtgtg ccacttccat tgatcactga atctgtattt
    13681 gcccgctata tttctgctta taaagaagaa cgcgtacaag caagcaagat tttatctcgt
    13741 acgaacgatt ttgagttcac gggagacaaa aaagaattgg tcgaaaaaat ccgagaagcg
    13801 ttgtatttca gtaaaatcat gagttatgcc caaggatttg ctcaattacg tgtcgcttca
    13861 aaagaatttg attgggactt gccatttggt gaaatcgcaa aaatctggcg cgctggatgt
    13921 atcatccgag ctcgattctt gcaaaaaatt acggatgcct atgacaaaaa tcctgagatc
    13981 gaaaatttat tgctagatga ttacttcgtt gaaatcacga aaaaatatca gcaatcagtc
    14041 agagacgtcg ttgccttggc tgtccaagct ggcgtacctg taccgacttt ctcatcagcc
    14101 atcgcttact tcgattcata cagagcagaa cgtctgcctg caaatataat ccaagcccaa
    14161 cgcgattact ttggcgcaca tacctatgaa cgtgtcgaca aagaaggaat cttccattac
    14221 tcatggtacc atgaagaata atagtctttc ggctgttagg aaatgagaaa ataaaaagag
    14281 gacgaaagag ctgaagtcga ttgttatgag tagacttcag ctctttttta aaattgctat
    14341 ccatgataaa atgactatag atttttaagc atattatcgg tataatgata gagtttttaa
    14401 aaagccagta gaatagaaag gataaaataa taaatgagca atattctaat cattgaagat
    14461 gaaaagaact tggcacgatt tgtcgagcta gagttgaagc atgaagggta taacgcagaa
    14521 gtccactaca acggccgaac tggtttagat gcggcattaa ataatgagtg ggatgccata
    14581 ttgttggatc tgatgctccc agaattgaac ggtttagaag tctgcagacg tgtacgccaa
    14641 gtcaaaaata caccaatcat tatgatgact gcaagagatt ctgtgatcga tcgtgtatct
    14701 ggacttgacc acggagcaga tgactacatc gtcaaaccat ttgctatcga agaattatta
    14761 gcacgtcttc gtgcattgtt gcgtcgaatc gatattgaag gcgataaaaa tgtggctaaa
    14821 caaactacta ttacttatcg cgatttgact atcgaaaaag aaaaccgtgt cgtacgtcgc
    14881 ggaaatgaag taattgaact aacaaaaaga gaatacgagt tgctgcttac tttaatggaa
    14941 aacgtgaacg tggtattagc acgtgacgtt ttactaaata aagtgtgggg atacgaaaca
    15001 gaagttgaaa caaacgtagt ggacgtatat attcgttatc ttcgcaacaa aattgacgtt
    15061 cccggggagg aaagctatat ccaaactgta cgcggaacag gttatgtgat gcgctcgtga
    15121 taaagccgaa aaaatcggaa aaaagagaac tgaaagggcc ctccttgaca atcaagtggg
    15181 cctttgcgag ttctttcttc atattcgttg tgtttacaat tttcgctgtc attacctata
    15241 aatcatctat caatctgatt gtggcaaaag aaagaaacaa tgtagagcgt acgatttcag
    15301 aagtagcttc tcgtttggct aactcggatg aagaactgac attagtaaat acgtatcgta
    15361 atctgacgaa agcgacaaat gacggagatg aggtcgtaga tcatacttca ctggtcgaag
    15421 gaaacttaat gaagatcgat tcctttatag ctgagctagg gcagccatca atggatcttt
    15481 atgtttatga tttggacgag aacttgattt ttaaaaccca tgaaaacagt cgaaacctga
    15541 ttcagactac acgtaaagtt ccaacgatcg ttacactaga aggaaaaact ggctttttat
    15601 ctatccagcc tatatattct aaaggtacaa gagaaaagat cggctatgcg caaagcttct
    15661 atgaattatc ttctttctat gatattcgaa ataagctatt attgactctt attgttttag
    15721 aagttgtttc tttgatctta agtagtattt taggtttctt tttatcttct tatttcttaa
    15781 aaccactcaa ggtactcaga gatacaatgg atactatacg taaagatccg caatcagata
    15841 tccacatgcc tgaaatcgac acaaatgatg aattggcaga tttagctgaa atattcaatg
    15901 agatgcttga ccgtatgcgt ttgtatattg aacaacaaga gcaattcgtg gaagacgtat
    15961 ctcatgagtt aaggacacct gttgcaatta ttgaagggca tcttagtctg ctaaatcgtt
    16021 gggggaaaga tgatcctgag atattagaag aatcattaag cgccagcatg caagaaatta
    16081 gccgtatgaa aagcttagtt caagagatgc tagacttatc aagagcagaa caagtagatg
    16141 ttcattatgc gaatgaaaca actaaaggaa aagaagtcac ctatcaagtt tataataatt
    16201 tcaagatatt atatccagac tatgtgatca ctttagatga tgatttgaca aaagaagtga
    16261 ccctgcaaat ttatcgtaat cactttgaac aattaatcat tatcatattg gataacgcag
    16321 taaagtattc aactacacga aaagaagtcc atatctctat ttcttccact ctgaatgaat
    16381 ttgagatcgc gattcaggac tttggcgaag gaatacccaa agaagacctt aataagatct
    16441 tcaatcgttt ttatcgagtg gataaagcaa gagctagaac gaagggtgga aatggtctgg
    16501 ggttgtctat cgctaaacaa ctggttgaaa actataaagg acgtatctta gcagaaagtg
    16561 tagtagggca agggacaatt tttagaatct ttattcctat cgcaaaggca gaagacaagt
    16621 aaagcatgtg ctttacttgt ttttttatat atccaacaaa gaataaggta caaaatacaa
    16681 gcaagttaga aattcaggga tgtcattata aaaaaaacta gcgaacaatt aaatagaata
    16741 acatccgtta attaaacgta agtagctttt agatgaacga aaaaacaatg aaatgctgta
    16801 atattcgtgt ttaaaaataa taaataaaaa tagggaattt tctattgcaa ttttataaag
    16861 agattgctat attattattt gttctaaatg attcctttaa ggtgtcacta aaaattataa
    16921 aaaatagggt tgacgcactt ttgatgtcat gttataataa cgaagtcgtt tggatgaggt
    16981 agctaataaa gcttgatttt atcgaaaaaa acttcgaaaa agttgttgac aaataacaat
    17041 aaagatgata tgataatcaa gtcgctgcta atgagtgaca aagacgttta gaaaaaataa
    17101 acaaagaagt tgttgacatt ctcttctgaa tctgataaga ttaaagagtt gttgaaacaa
    17161 aaagattaga cctttgaaaa ctgaacaaag taagacaaac caaatgtgta gggcgtcttg
    17221 attcaattca agacaacaaa catttttaac aagcaagcaa tatgctagca aacaaattga
    17281 gcttaacaat cgcaagattg ttcgaacttt ttatgagagt ttgatcctgg ctcaggacga
    17341 acgctggcgg cgtgcctaat acatgcaagt cgaacgcttc tttttccacc ggagcttgct
    17401 ccaccggaaa aagaggagtg gcgaacgggt gagtaacacg tgggtaacct gcccatcaga
    17461 aggggataac acttggaaac aggtgctaat accgtataac aatcaaaacc gcatggtttt
    17521 gatttgaaag gcgctttc
//
LOCUS       DAPBCF010000054        17006 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.055, whole genome shotgun sequence.
ACCESSION   DAPBCF010000054 DAPBCF010000000
VERSION     DAPBCF010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.055"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..127)
                     /locus_tag="RD508_002229"
     CDS             complement(<1..127)
                     /locus_tag="RD508_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HDT7736772.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(231..542)
                     /locus_tag="RD508_002230"
     CDS             complement(231..542)
                     /locus_tag="RD508_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDT7736773.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(544..741)
                     /locus_tag="RD508_002231"
     CDS             complement(544..741)
                     /locus_tag="RD508_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HDT7736774.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1135..2862)
                     /locus_tag="RD508_002232"
     CDS             complement(1135..2862)
                     /locus_tag="RD508_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HDT7736775.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2855..4048)
                     /locus_tag="RD508_002233"
     CDS             complement(2855..4048)
                     /locus_tag="RD508_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7736776.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4235..4879)
                     /locus_tag="RD508_002234"
     CDS             complement(4235..4879)
                     /locus_tag="RD508_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7736777.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4973..5107)
                     /locus_tag="RD508_002235"
     CDS             complement(4973..5107)
                     /locus_tag="RD508_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HDT7736778.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5109..7241)
                     /gene="feoB"
                     /locus_tag="RD508_002236"
     CDS             complement(5109..7241)
                     /gene="feoB"
                     /locus_tag="RD508_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDT7736779.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7238..7711)
                     /locus_tag="RD508_002237"
     CDS             complement(7238..7711)
                     /locus_tag="RD508_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDT7736780.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8112..8336
                     /gene="nrdH"
                     /locus_tag="RD508_002238"
     CDS             8112..8336
                     /gene="nrdH"
                     /locus_tag="RD508_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HDT7736781.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8495..10654
                     /gene="nrdE"
                     /locus_tag="RD508_002239"
     CDS             8495..10654
                     /gene="nrdE"
                     /locus_tag="RD508_002239"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDT7736782.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10704..11669
                     /gene="nrdF"
                     /locus_tag="RD508_002240"
     CDS             10704..11669
                     /gene="nrdF"
                     /locus_tag="RD508_002240"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDT7736783.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11758..12897)
                     /locus_tag="RD508_002241"
     CDS             complement(11758..12897)
                     /locus_tag="RD508_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7736784.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13206..13919)
                     /locus_tag="RD508_002242"
     CDS             complement(13206..13919)
                     /locus_tag="RD508_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDT7736785.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14173..14874)
                     /gene="nagB"
                     /locus_tag="RD508_002243"
     CDS             complement(14173..14874)
                     /gene="nagB"
                     /locus_tag="RD508_002243"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDT7736786.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15108..16640
                     /locus_tag="RD508_002244"
     CDS             15108..16640
                     /locus_tag="RD508_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7736787.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16831..>17006)
                     /locus_tag="RD508_002245"
     CDS             complement(16831..>17006)
                     /locus_tag="RD508_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7736788.1"
                     /translation="FMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQT
                     VVFKGKRNLENKK"
BASE COUNT         5278 a         3493 c         2910 g         5325 t
ORIGIN      
        1 atgaaaaaac acattccact aaatttgatg ccggttttcc ttgaggtttt gttccagcac
       61 ctcctttaat ttttttaagc tcttgatctg aacattgttt agcatttagt ctattttttt
      121 cttccattac gattccccct acaaactata aatactttta tgtcactgat tcaatatacc
      181 tatttttcta atcaaaaaat tttgagacat atttaatatt ataagtatca ttaaaattga
      241 gatttatctc cataatctgc tcgatataaa ccatttattc cagcagttct tccaatttca
      301 ctcaaatttc ttattaattc ctcttgatat tcagtgaatc ttattttatt agtataagca
      361 gtaaaatata gataattcac caatctattt attaaaggac tgggatctaa ttcatatttt
      421 tgtttttcta attttaaata taccttttgt aaaacctcaa gaatatcaga atatttagga
      481 tctttactta tagatatatc attatataat tcatgaacaa tttgcttagc attttttttc
      541 attttagcac ttccctggaa ttgctccacc taaaaaacca cctatagaca ttcctgcaat
      601 acaagtagtt gccttggccc aatcgaccgt acatttattt ttagtgcaat acactccatt
      661 tccataatat tttccactat gagtggtacc cccatagata agttgtgtct ctttaataga
      721 caaaattttt aaatgtttca taatctaatc acccctaaat taatgttttt agactattat
      781 tctaacattc attaaatttc aaaaaacaat tccttcttga aacgtagcaa aataattcct
      841 gaataagaat ttaatcactt ttaagtatat aaactatgta tattctttaa tattttttga
      901 gaatgcactt cgtacataat aaactttaat cacattagtc tttcatacct acgatcgatc
      961 tctttgactc gcacccataa attcataata gtttgtcggc gtctttgaac gtttcgaaga
     1021 tgagctacgc attctctttt tttatagaca aaaaagatag agacgaacat ggagcttcca
     1081 aatttggata tttgatccaa ttttggaagc tccatttatt tcgtgtctgt ctttttattt
     1141 tttccagctt tcgactaatt cttggttctc tttgatccag tcttttgctg cttgctgtgg
     1201 atcttttcca ttgttgattt ccaacataac tttttccata tctttttctg accaatggaa
     1261 attgtctaat actttgtaag cttctggctg gtcttctttc aatccttttc gaaccatcgt
     1321 atggatctgc tcttcgcttc ccattccgtt ttcaggatct tctaagtatt tcagatcata
     1381 tttggcaaac atccaatgag gtgtccatcc tgtaactaca attggttcgt gttttttgat
     1441 cgcttgacct agtgcaacgg tcattgctcc tgaagaagat gtctctactt tccagtcttt
     1501 caagttgtca tatttttgga tcgtgttttc agcagccgta actacaccag ctcctggctc
     1561 gattcctatg attttcttac ctgcctgatc ggttaactca tcgatcgaat ttacatccat
     1621 gtaggctggc actgctaaac caacttttgc tcctgtcaaa ttggcaccta ggtcttcgac
     1681 ttgatcttta tattgtgcat attgtgaacc atgagtttta ggtagccaag ctgaaaccat
     1741 ggcatctgac tcgccatttg aaacagattt ccacatgatt gaattatcta atggcgtcat
     1801 cgttacatca tagcccattt gtttcaatac ttcaccgact acatttgttg aagcaacttc
     1861 tgtatcccat tcaacataag ataagttgat acgttttgtt tctttggcag atgaaaaact
     1921 ccctatacca atcgcaccta agatcactac tactacagca ccaatgatca gtccttgacg
     1981 ttttttactt ttctgtgttg ttgctcctgc agctttttta ttgtttggct ggttcaaatg
     2041 ctgtgtaaaa cggtcaatga tgattgctaa gataactaat gcaaccccgt tgacaaatcc
     2101 attcccgact tgtgctcttt gcaatgctga taatacgccg cgtcctaagc cgggtgcacc
     2161 gatcatagag gcaataacga ccattgaaag tgacagcatt gttgtttgat tgatccctgc
     2221 catgatcgta cttttagcta aaggcaattc tagtttgaat agtttttgac gacttgtgct
     2281 cccgaatgaa tcagaagctt ctactaattc tttaggaact tgtcgaatcc ctaaattcgt
     2341 aaaacgaacg gttggtggca gagcaaagat gactgaggca aatacccctg gaaccatccc
     2401 gataccgaaa aatgcaactg ctggaatcaa ataaacgaat cctggcattg tctgcataaa
     2461 gtcaaggatc ggtttgataa tactttgggc tttactgctt tttgccatca agatccctaa
     2521 tggtacccca atgatgatcg agatcacact agataaaaga acaagtgtga cagtattcat
     2581 caaatcattc catagacctt ggttataaat aaaccataga ccgattaatg tgaacaacgt
     2641 aagtcctgga cgtttcttag aaataaagaa agctgctacc gtcaataaca agataaacaa
     2701 aggagctgga atcactaaca gtaaatttgt aattcccgac atcactgcct gtccaatcgt
     2761 ttgtaaaaat gaaaataggc cagaaaaagt tgtcgtaaac cattctgtga tattttctac
     2821 ccagtttgcc actggtaatt gatagttcaa tagattattc atgttcactc acctcgcttg
     2881 tttctgctaa tgcttcaatc acactacctc ggatgacgac accttttaat tttccatcct
     2941 ctacaactgc aagtggagtc ggtgagtcat aaataatatt gaaaatatca cttaccacca
     3001 tgtctttccc aatcaccgtc acattttcat ctaggaagtc gatcaatgga cgtttttgct
     3061 tcctagcttc taacgcttga tctgcagtga tgatcccttt caggtgtctc tttctgtcaa
     3121 cagccatcag catgctgact tcttcattac gcatccttgt caatgcaacg tttggtccat
     3181 cagattcgat attcgtcgtc aatgcaggta ccatgatgtt ttgagccgta agcactttgg
     3241 aacgatcgac ttcttccaca aattcacgta cataatcatt tgctggattg gtcaatattt
     3301 cttcacctgt tccgatctgc atgatttcgc cgtctttcat caaggcgatt ctgtccccaa
     3361 tccgtaaagc ttcattcaaa tcatgggtaa tgaaaataat cgttttttga acattggctt
     3421 gcaggtccag taattcgtct tgcatttctc gccggatcag cggatcaaga gccgagaacg
     3481 cttcgtccat cagcaagatc tcaggatcat ttgctaaagc tctggctagg ccaacccgtt
     3541 gttgcatccc accagataac tgactaggat attggtcttt aaatgaaagc aaactagaat
     3601 tttctaatgc tttttctgct ttttcttgtc gttcttcttt aggtacacca cggacttcta
     3661 acccgtattc tgtattttcc aagatcgttc gatgtggaaa cagaccgaag ttttggaaaa
     3721 ccatattgat tttatgacga cggacttctc gcaattcttc tttgcttaac ttcgatacat
     3781 cttctccatc aatatagata ctgcccgaag ttggctcaat cagacgattc aatagacgga
     3841 tcaatgtgga tttcccactc ccggaaagcc ccatgatcac gaagatttct ccttctttta
     3901 cgtcaaaatt cacgtcatac acaccaaccg ttgcaccggt tttctttaaa atctccgttt
     3961 tcggctggtg atcattcatc atatctaaag cggcttgtgt ctttttacca aatatctttg
     4021 ttaaatgttt tacttctact tttaccaaac aaattctcct tttttatgta aattcatttt
     4081 tctttctgaa aaaagtgacc acactatgtt aacatcatgt agtcactttg tcaaaaatga
     4141 aagaaatttg cttgtccaaa ctgaaaaaaa cttggctaaa tctttgtaaa taaaaggttt
     4201 agccaagtta atattttttt aatatttcac acaatcattc tgcaagctga tgctccgggt
     4261 aaaaaaagtt tgtcatacgc tgtagtgtat attcatttcc aataaaatga acgatgtccc
     4321 ctgccgtaaa tttagcatag gggccaggtg aaacaagcag ttcttcatta tgagaaattg
     4381 cgataactgt ggcgccagtc gcctgccaga tattcaactc gctaattgaa cggtccagat
     4441 gcattgcttt ttctgataaa gataattcaa acggaagtaa aggattcatc ttatgtattc
     4501 gcttcgtttg attgaccagc tgatccaata attgagaaaa atgattcagc tcatcttgtt
     4561 gcttctccac acttgccatg atttctgctt ttgtatcttg gatggattgt acatcttgat
     4621 attgcaatag gaaatctttt gctttttcct tcgaagcaac aaatgcccca cttccatgcc
     4681 gtacttccat gattccaaga tctaccagca cattgatagc cttgcgggta gtctcaggag
     4741 aagcattgta cgtactggca agtgttgagc gggcatggat cttctcaccc actttatatc
     4801 ggttttcaac gatacgttcg gctaaatcaa cagcaatctg ctggtagcgc gggcggacga
     4861 tttttttctt tccagacatt ttctttcctc tttctttttt tactttccct catcttacta
     4921 tgctctagca aaataagcaa aaaaggggag aatagcctct tgcaacgact gatcatcgct
     4981 tgatctgttc cttttttact gggcaagctg tttgacagtc atcacaattc ttaccggatt
     5041 ttaaacgagt atagacaatt gcgcctgcac ttccaaagat taacacactt aataagaatg
     5101 tcgccatcct attcctctcc ttctaatgac aatatagtat aaaactggtt cttggatttt
     5161 ggctgacgga acaaaacata aacgagtcct atcatcagta aaatagcaag atacgtccct
     5221 aacgctacct gtccaccctc caataagtgt cccaactgat aaatcacaaa actaactaaa
     5281 taagctaaac cgcattgata gcctatggcg atccaagtcc atttcttggc attcatttcc
     5341 cgatggatag ccccaattgc cgcaaaacaa ggcgcacaaa gtaaattgaa ggctaacaat
     5401 gaataagctg ctgcgggagt atatgtgtgt tgtagcactt gccagatttc tctgccattt
     5461 tcggatactt ccgcatgacc aaacaaaata ccaaatgtgc caataatatt ttctttagcg
     5521 accaatcctg taatcgctgc gactgttcct tgccagtttc cccaaccaag cggctgaaaa
     5581 acaactgcca ggattcgccc gaaaaaggct aagatacttt ggtcttcaga aacaggttga
     5641 gcataaaaat tataagaaga gctgaaccag atcacgatac tagaaacaaa gataatcgtt
     5701 cctgcttttt taacaaaaga cttgctgcgg tcataggttt gtcttaggac cgctgaccat
     5761 tgaggaaaat gatatgcggg caattccatg ataaaaggag ctgtatctcc agcaaacaaa
     5821 cgtgtttttt tcaagctgat tccagagaaa ataattgcag tcataccaag aaaataggca
     5881 gaaggagcta cccaagattg atgaggaaaa aaggcccctg ctactaaggc aataatcggc
     5941 aactttgcag aacaaggcat gaaggttgtg accatgatcg tcaaacgacg atcttgctcg
     6001 ttttcaatcg tgcgactggc catgacgcct ggcactccac atcctgtagc aatcagcata
     6061 ggaatgaagg attttcctga aagaccgaat ttcctgaaaa gtcgatccat gacaaaagcg
     6121 atcctcgcca tatatccgca gtcttccaga aagctcaagc ataaaaacaa tataatcaat
     6181 tgcggtagaa atcctaacac tgctcccacg cctgcgatga tgccgttcaa gatcagctcc
     6241 tgcatccatc ccgctacttg ccattcagct aacaatctgc caacatgttc tggtaaccat
     6301 gtaccaaaca atgtgtcatt gatccaatct gtccccattg ttcctactgt ttgaatagcc
     6361 agataataga tcagccacat cacaaatgcg aagatcggca aggctaacca acgattcgtt
     6421 gcaatctgat cgattttgtc actcatcgat aattggaaag aatcatttga cacaacacag
     6481 agtgtacata gttgggtaat aaattcataa cgttcattga ccagaatcgt ctcactatcg
     6541 tcgtccaata gtttctctgt taactggatc agttgctcga tctctttttg ctgagaaact
     6601 gctatctcgt aatcctctct taccttctga tctcgttcaa aatatttcat tgcataccag
     6661 cgtttcttgc cgctttgttc tcctagtaca tcttcaattt catgtaaagc tgcttctaaa
     6721 cgtggatcat atgtacaggg aacaggaata gaaggccgct tttttgcaga ctcctgaatc
     6781 ttttcgatta gtttttcgat tccttgcttt ttcaatacgc tgattggtaa aactggtaca
     6841 ccaagaccat aggaaagctt ttctagattg attttttttc cttctttttt gatgacatcc
     6901 atcatattca gaccaatgat cataggaatg tctaaatcca ataactgcgt agttaaataa
     6961 agatttcgtt ctaaattggt agcatcaata atgttgatga tcagttcagg ctgttcctga
     7021 accaaataat ctcttgcaat cacttcttct ggtgtataag gagacaaaga atagatgccg
     7081 ggtaggtcct gaatatgaat gttcggattt tttttcaacg atccttcttt tttttctact
     7141 gttacgcccg gccaattccc tacatattga ttcgaaccag tcaagagatt gaacaagcta
     7201 gttttcccgc tgtttggatt tccgactaac gcgatattca ttctttttcc tccctttgta
     7261 tcaagattag ttcggcctct gactttcgta acgtcagttc ataccctcgc actgtcagtt
     7321 cgattggatc tcccagaggg gctagttttc ggataactat ttttacattt cgcgtcaatc
     7381 ccatatccat taaccgtcgc ttcactgcgc cttgtccgtg gattgctacg acgatcccag
     7441 tctctcctgc ttttaattga tcaagagaag tccagctttc agaggaagca gtctttttat
     7501 tgacaaagat ttgacctagt atttcccgac ttactgccac tcgatgactt tttaccagta
     7561 aaatggcatt gttgcctgat aaattgacga cgacgatttt acttccggca acgatcccga
     7621 tattttgcaa atggcgtttt gttttttctt ctgtttcgat tcgttcgact tgataaacga
     7681 aattctgctt tgcctgcgct aaggtctgca tattgattcc tctcttgtga aataaatcat
     7741 gtattaaaat cattcattat atgttctaat tttcttacgt gttacgcaaa taaatgagaa
     7801 tcattctcac atagaatact ctcggtaatt gagaatgtca attatacttg tgatattatg
     7861 agcgaatctt tagtattgat agataaaaat gagaaaaaaa tatttcttca tagttttcca
     7921 caattttttc tctattaaat ttgctatttt cccacacgat acttgttttc agctcttttt
     7981 tcaaaaacac aaaacttagt attccacagt ttccacaaca caatatgtag tgtttgttgt
     8041 ttgacttttt tactaagagt tttatactat ctattataga taataagaat gtgttagagg
     8101 aggcactcac catgaacgta aaaatctttt ctaaaaataa ttgtatgcaa tgtaagatgg
     8161 tcaaacggtt tttaacagaa aatcaaattg cttttgaaga agtcaatatc gatgaacagc
     8221 ctgaagcagt agactggttg aaagcacaag gattccaaag tgttcctgtc attacttctg
     8281 atgcagaaac agttatcgga ttccgtcctg atcagttgcg taaacttgcc agctaacatg
     8341 actaaaagaa tcaaaacgtg atacatggat ttgaagggct tgagacagca ccagtttttg
     8401 tcgcaaactt ccaaatcctt ttttaaagct taaaaacaat gcaatgattt gcaatcaagc
     8461 atcatcaaat acgaaatgaa ggttgggcgt acgtatgagt cttaaaaatt tacaagatgt
     8521 cagttatttc aagctgaata atgaaatcaa tcggccagtc aatggtcaaa tccctttgaa
     8581 taaggataaa gaagctttag ttgccttttt tgaggaaaat gtcaaaccaa atacgatgac
     8641 ttttccatct attatggaaa aaatcaatta cttgatcgat caagaatata tagaagcaga
     8701 attcattcaa ttgtattcac catcatttat tgaaaagcta tatcaatttt tggacgagca
     8761 acatttttct ttcaaatctt ttatggctgc ttacaaattt tattctcaat atgcgttgaa
     8821 aaccaacgac ggttccgctt atctggaaac ttatgaagat cgagtagcct tcaatgcgct
     8881 ttactttgcg aacggggatg aagaattagc acttgctctt gcagacgaaa tgatccatca
     8941 acgatatcag ccagctacac cttctttctt gaatgctgga cgtaaacgtc ggggcgaatt
     9001 ggtgtcttgt ttcttgactc aagtcactga cgatatgaac tctatcgggc gctcaatcaa
     9061 ctctgctttg caattgtccc gtattggtgg cggcgtaggg attactttat caaatcttcg
     9121 tgaagccggc gctcctatca aaggatatga gggtgctgca agtggtgtcg ttccagtcat
     9181 gaaattattc gaagatagtt tcagctattc taatcaatta ggtcagcgtc aaggagctgg
     9241 cgtggtttat ttgaacgttt tccatccaga cattattgct ttcctttcag caaaaaaaga
     9301 aaatgcagat gaaaagattc gcgtaaaaac tctttctctt ggcgtgatcg tacctgataa
     9361 attttatgaa ttgacacgta aaaacgaaga tatgtattta tttagtccat atagtgtcga
     9421 aaaagaatat ggtgtcccat tctcttatgt aaatattaca gctgagtatg atcatctagt
     9481 tgcaaatcca aacattcgca aacaaaaaat caaagcgcgt gatcttgaaa atgaaatctc
     9541 aaaattacaa caagaatctg gctatcctta cgtaatcaat attgatacag cgaaccgcga
     9601 gaatccaatc gatggcaaga tcatcatgag taatttatgt tcagagattt tacaagttca
     9661 aacgccttct gtgattaacg gcaaacagga atatgaagta ttaggaacag atatctcatg
     9721 taacttaggc tcgacaaata tcgtgaattt gatgcaaagc cctaactttg gtcaatctgt
     9781 gcgtacgatg actcgtgcat tgacatttat tacagatgca tctgatatcg atgtcgtacc
     9841 accgatccaa aacggaaata agctgaatca tacgattgga ttaggtgcca tgggcttaca
     9901 cacttatctt gcaaaagaac aaatggaata tggctcagag gattcattag actttacaaa
     9961 tatttacttc atgctgttga attattggac acttgttgaa agcaacaata tcgctcgtga
    10021 aagaaaacaa gttttccata attttgaaaa atcagcttat gctgacggca cttatttcga
    10081 aaaatacgta actggagaat tccagccaaa atcagaaaaa gtcaaagcat tgtttgaagg
    10141 catttttatc ccaactgctg aagattggaa tgctttgaaa caagcagtaa tgaaagatgg
    10201 actgtatcat caaaatcgct tggcagtagc accaaatggc tcaatttcat atatcaacga
    10261 tacgagtgca agtattcatc ctatcactcg catgatcgaa gaacgccaag agaagaaaat
    10321 cggtaaaatt tattacccag cgccttatct atccaatgag acgattccgt attacacttc
    10381 tgcttatgat atggacatgc gtaaagtaat cgatgtttat gcaacggcac aacaacacgt
    10441 cgatcaaggc atgagtttga ctttattcat gcgttctgaa atcccagaag gcatttatga
    10501 atggaagaca acaacgaagc aaacgacacg tgatttgaat attttaagac attacgcttt
    10561 ccacaaagga atcaaatcca tttattacgt acgtaccttt actgatgatg cagaagaaat
    10621 cggaagcaat caatgtgaaa gctgcgtgat ctaatatcat agatagattc gcttattcat
    10681 attttaatta aaggagcatt ctcatgtcag aaacatatta tgaagcaata aactggaatg
    10741 aaattgaaga tatcattgat aaatccactt gggagaagct gacagagcaa ttttggctag
    10801 atacacgtat cccactttca aatgacctag atgattggcg tacattgtct caattggaaa
    10861 aagatacagt aggacatgta tttggcggtt tgacactgct agatactgtc caatctgaaa
    10921 gtggcatgga tcagttgcgt aaagatgtcc gcactcccca tgaagaagcc gttttgaaca
    10981 atattcaatt catggaatcc gttcatgcca aaagttattc ttctattttt agtacactga
    11041 atacgaaaaa agaaatcgaa gaaatttttg actggacaaa tacgaatcct tatctgcaaa
    11101 aaaaagctga gcgtatcaat gaaatctaca aacacggtac accgctagaa aagaaaattg
    11161 ccagcgtctt tttagaaaca ttcttgttct attcaggttt ttatactcct ctttattatt
    11221 taggaaacaa caaattggct aacgtagcag agatcatcaa actaatcatc cgagatgaat
    11281 ctgtacatgg aacctacatc ggttacaaat tccaattagg attcaacgag ttacctgaag
    11341 cagaacaaga aacgttaaaa gactggatgt acaatcttct ttatgagctt tacgaaaacg
    11401 aagaacgtta tacagaagaa ttatacgatc caatcggctg gacagaagaa gtcaagacat
    11461 tcctacgcta taatgccaac aaagcattga tgaacctagg gatggatcca ctctttccag
    11521 atactgccaa tgatgtcaac ccaatcgtaa tgaacgggat ttcaacaggc acaagcaacc
    11581 atgacttctt ctcacaagtc ggaaacggct atttgttagg tcatgtagaa gcgatgaaag
    11641 acgacgatta tttgattgga ttggaataag gatttatttt aattcaaaaa tttttcgaaa
    11701 aataaaaaga gtttagcgta cagatatttt aaatgtacac tgaactcttt tttatgctta
    11761 ttcacttgtt tcttccagca cttttggact gtctaacttt tccgaaacat gttccattct
    11821 tctcaataaa tagattttcc ggatatttaa tattatcgtc ttaatcactg catagacagg
    11881 tatgcaaatc agcatgccta atattcctgc gacacttcct gctccaatca ataccaagat
    11941 gatcgtcaaa ggatggatat tcattgattt cccaaataac aacggcttga tcaaatttcc
    12001 atctaattgt tggatcacta aaatcgacaa cgccatatac aaagcttgaa atggagagat
    12061 aaacaaaccg acaatgattg ctggtaccgc tccaataaaa gggccgacat acgggataat
    12121 attcgtgatt ccgcaaatga ccgcaagcaa caagctataa ggctgatcga atattctcat
    12181 tgccaaaaag ctcattacac caataatcaa agcatctaag atcgtactgc tgatataggc
    12241 agataatgtt tcgtttaatt cttttaccgt ttggcgtaac tctttacgaa tcgctttcgg
    12301 aaagaagtga gacaacgcat caataaattt gtgcccatcc ttgaacataa atagcaaaat
    12361 aaatggaacg gtaaataaca aaataaaaaa ttgcatcata aatgaaatga tttttgagac
    12421 acttgcagat aaactgacta atatgatatt gaacaaatta ctaagagata aatttgctga
    12481 tgctaattgt tcttccaaat tgaaattttt aaactcttcc cgctgcgcca attcatttaa
    12541 ccatttgctt gtttcatctg catacattgg caagctctgg gtcaattgaa ttgtctgttc
    12601 cattaactga ggcactacat tcatgacagt taaaacaact aaaatgatta cgaccaaaaa
    12661 cgtcaataaa aaaccgaaca ctctcgggat ccgatgcttt tcgagaaaaa caacgattgg
    12721 atcgaacata taatagataa aaccagcaac aagcaatggt aaaaaaattg ccgaaagcat
    12781 tttcaatatt ggactaaaaa tattcggcat ttgtaaaata aagtacacgc cgatgatcgt
    12841 gagtactagc tccactgtcc agaaaaataa ttttgattgt ttaaaacgtg attgcataca
    12901 tctcctccaa ggtcctttga tacttctatt ctatcattta acaaagagtt acgcgctgag
    12961 attttcattt gcttaaaaaa aacaaaaaaa ataaacatat tttaatgagt agacgagtac
    13021 ttaaacaaaa acacggtttg gagtagtgac aaaaattata ctgcagtccc tttttccaaa
    13081 taaacggtgt tcaaaagctt gcatcttcgt aataagccca gccaaacgaa aaatataagg
    13141 aactattttt atttggctgg gcttattact tgatgtagga catctatttt acaacctcag
    13201 atcatttatt gcgcaatact gactaaatgc aactttgtga tatttttgtg tacggacaac
    13261 tcctcgatca catcggcata agtgagccct tttggaagat caatcgtata gatatttttg
    13321 tacactcggt agtcatcaac gaattttacg tcaaaattca catcttcgat tacgatattt
    13381 ttctcttcaa aataatcggt aagaaaatct ttggtttctt ttctatggat aaattggatt
    13441 tctaactttt tagtcgtagg tacatggatc acgcgtttca ctactgtgag tgcaatagca
    13501 atcccgataa aactgatgat cgcaatggaa tagtaaccca tgccgatggc gatccctaat
    13561 ccagcaattg cccataaaga agcggcagtc gtaagtcccg tcaccgattg tttcgtgacg
    13621 atgatcgttc ccgcgcctaa gaaaccgaca ccactcacca cttgagcaat cagccttgct
    13681 tcatctgaac gaatcgttcc agcaagctgt ggatactcta aagcatctct taatgcacca
    13741 ctagcgatct caacttggat caatgcaatg atacatgctc ccatacaaac taaaatatgc
    13801 gtacgcatac ctgctggacg atttttatat tgtcgttcaa aaccgattgc tccgccaaat
    13861 agcatagcga tccctaaacg taaaataatc tctggaattg tcaataccat atcattcatc
    13921 taaacaccct ccagtccaat atatcatgtc tgaaaggagc agacaaaaaa agtgcaattt
    13981 ttacctctta cgaaaaaagg actgtgacaa aatttttgtc atagtccttt ttatgaataa
    14041 acggtgttca atcagctgac cctcggtatt actcaacaaa cggcaaaata tggggagcta
    14101 tttttccttt gtcttctcta atactcaggt caaaacgctg atttcacaac ctctttagcc
    14161 tactattgaa aattacaact tacttgctgc ttcttcatcg atgatcacaa caacattgtc
    14221 gtgattttgc aatacacttg ctggcaaatg attcgttaca ggtccttcaa tcatcccttt
    14281 gattgcatca gctttgcttt cgccaaatgc catcaagacg atttctttac ttttcataat
    14341 tgaaccgatt cccattgaaa cagcttttgt tggtacatct tctgctttat cgaagaatcg
    14401 tttgtttgca ttgattgttg attctgttaa gtcaactact gaagtcgttc cgtcaaatga
    14461 agcaccaggt tcattgaaac cgatatgtcc attttgcccg attcctaaga tttggatatc
    14521 gattggatgt gcatcgatga tttgatcata ctttttgcat gctgcttcca gatcttctgc
    14581 ttttccatct ggtacaaacg tttctttgaa tggtttttta tcaaataatt ggacatccat
    14641 gaaatgacgg tagctttgtt catctgaacc gcctagtcca acgtactcat ctaagtttac
    14701 agaagtcatt tcactgaaat ccaaatcgct tgaagtcatt tctttatata aagtaactgg
    14761 tgtgcttcct gttgccaatc ctaatacttt tgcacctttg ttcatacctt ctttgatgat
    14821 ttcaaatgct ttttttccgc cttcttcagc gttttttaca cgaatgattt ccatagtgat
    14881 tgctccttta tattttggta tagcccaatt atagcattct ttttttcttt ttacaataat
    14941 tagtatagac caaattgcat ttttttcatt ttcttgacaa taaataggaa tccgtgttag
    15001 gtttcataag atggttcaat caaacaatcc atgttgcatg aaaaccaagc aagtgattca
    15061 ctgtggacgc tttatgtctg cagttttttt atgaaaaagg agttattatg agtatactga
    15121 cattaaacaa cattacccag caatttggcg acaaaatcct ctatgaaggt gtcgatctgc
    15181 aattaaatgc tggcgaacat cttgggctga ttggacaaaa cggagccggt aaaagtacat
    15241 tgattaaaat catcactggt gagatcttac cagatgacgg acagatccat tggcaaaaaa
    15301 atattcacaa aggttacctc gatcaatatg tggaagtcga tgaaacatta acaatcgaag
    15361 aatttctaaa aactgcgtac gcaaaagaat acgaaaagga agaaaaaatt gcttttcttt
    15421 accaaacata tagcgagacc ttcgatgatt ccttgctgga aaaagctggg aaactccaaa
    15481 cggaattaga ccaaggagtg ttttatcaaa tcgacacctt agttgctgag atgagcagcg
    15541 ggttggggat cgatgtctta ggtttagatt cactgttgaa aaatctaagt ggtggacaac
    15601 gttcaaaggt gattttagca aaactacttt tagaaaaccc agatgttctg atcttagatg
    15661 aaccaaccaa tcacttagat gatcagcata tccaatggct gacgcagttt cttcaggatt
    15721 ttgacggtgc gtatatcgtg atttcccatg accaagaatt tcttgatcag atcaccaccc
    15781 atatcgcaga catcgagttt ggaaagatta ctaagtatac tggccatcta aaacaagcat
    15841 tgaaacaaaa ggaacaaaat cgcgaaagct atttgcgcca atatcatgct caacaaaaac
    15901 aaatcgaaaa gaccgaagct tatattcgaa aatacaaagc cggttcccga tcaacgatgg
    15961 caaaaagccg acaaaaacaa ttagataaaa tcgaacggct gacgcctcca gcttcagcaa
    16021 gtaaagctgt ctttgatttt ccattctcgc ctattgtcac gacattagca gtggaaacaa
    16081 ctgatttagt catcggatat gatcgaccgc tacttgcacc catcaatttg accatccgct
    16141 ttggtgaaaa tattgccatt cgaggcttca acgggattgg aaaatctact ttattaaaaa
    16201 cactgatcgg tgagattgaa aaaataagtg gcgatttcca cttcccagat aacacaaaaa
    16261 tcaattactt ttcacaagat ctgtactggg aaaatccatt agaaacacca ctacaatatt
    16321 taagcagtca atttccaaaa gcgactatca aagaattacg tcgccaacta gctaaagcag
    16381 ggttagttaa tcaattagca agtgaacctc tcactacatt aagtggtggg gaacaaacta
    16441 aggtgaaact tgcacagttg acaatgaacc aaggtaattt actgattctc gatgaaccga
    16501 cgaaccatat cgatcaagaa acgaaagaaa gcttacaaga cgggatacag aaatttccag
    16561 gaacagtaat catcgtctct catgaacaag aattttatca agatcttgtg caacgagtca
    16621 ttgagattga accaaaataa acgtttgatt gaatagttga aaaaaaggag ctgtgacaaa
    16681 agttttgtca caactccttc ttctgaataa atggtggcca attagctgac cttcggtatt
    16741 agctcaaaaa acggcaaaat atgaggagct atttttattt ggctattctt attacttgat
    16801 gcagaacagc ttttcacaac ctcttttcgt ctatttttta ttttcgagat ttctctttcc
    16861 tttaaaaaca actgtttgaa agaagaacgc acatccttga aaaacaagcc cgctaaccgt
    16921 tacacctaac cagccatact gctgccacat tgtcgtccct agcaatgaac cagccgcacc
    16981 tccaataaag tacataaaca taaata
//
LOCUS       DAPBCF010000055        16597 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.056, whole genome shotgun sequence.
ACCESSION   DAPBCF010000055 DAPBCF010000000
VERSION     DAPBCF010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.056"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..323
                     /locus_tag="RD508_002246"
     CDS             <1..323
                     /locus_tag="RD508_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7736789.1"
                     /translation="YNEELRTAYHFCQLLRYYFVKRGTEGFQETLKTISSTLPQSFKK
                     KFTIFHCYQSGISNAFKVSHSNGVTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGL
                     IFEN"
     gene            complement(706..1434)
                     /locus_tag="RD508_002247"
     CDS             complement(706..1434)
                     /locus_tag="RD508_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HDT7736790.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1412..2986)
                     /locus_tag="RD508_002248"
     CDS             complement(1412..2986)
                     /locus_tag="RD508_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDT7736791.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEEKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            3215..4153
                     /locus_tag="RD508_002249"
     CDS             3215..4153
                     /locus_tag="RD508_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7736792.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            4165..5076
                     /locus_tag="RD508_002250"
     CDS             4165..5076
                     /locus_tag="RD508_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7736793.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            5100..6572
                     /locus_tag="RD508_002251"
     CDS             5100..6572
                     /locus_tag="RD508_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7736794.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6623..7234
                     /locus_tag="RD508_002252"
     CDS             6623..7234
                     /locus_tag="RD508_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7736795.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            7264..9177
                     /locus_tag="RD508_002253"
     CDS             7264..9177
                     /locus_tag="RD508_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HDT7736796.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            9305..12286
                     /locus_tag="RD508_002254"
     CDS             9305..12286
                     /locus_tag="RD508_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HDT7736797.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            12283..13944
                     /locus_tag="RD508_002255"
     CDS             12283..13944
                     /locus_tag="RD508_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HDT7736798.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13984..14916
                     /locus_tag="RD508_002256"
     CDS             13984..14916
                     /locus_tag="RD508_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HDT7736799.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
     gene            complement(15275..16537)
                     /gene="guaA"
                     /locus_tag="RD508_002257"
                     /pseudo
     CDS             complement(15275..16537)
                     /gene="guaA"
                     /locus_tag="RD508_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
BASE COUNT         5297 a         2724 c         3352 g         5224 t
ORIGIN      
        1 gctacaacga agaattgcga actgcgtatc atttttgtca attattacgc tattatttcg
       61 ttaaacgagg tacggaaggc tttcaagaaa cccttaaaac aatttcatct acgttacctc
      121 agtcgtttaa aaagaaattc acgatcttcc attgctacca atcgggtatt tcaaatgcct
      181 ttaaggtgtc ccactcaaac ggcgtcactg aggggctgaa taacaagatc aagctgatta
      241 aacgaattgc gtttggttat cgcaactttt ataactttcg ggcacggatc tatttacaac
      301 aaggtctgat ctttgaaaac taaaaaaata tgcggcgcac agaacgcgcc gcatatcgga
      361 ctaagtttta ttcaaatttg tcttcaccaa cacgatttga cgaagagcct atttaaataa
      421 ctacatccat ctattctatc ttctaaaata gcctttttca tttcagttaa atagttcagc
      481 gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc tcagcggggg
      541 ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta aatattctaa
      601 tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact tttcaatggc
      661 tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata gaagcttttt
      721 acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa aatagctcac
      781 gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt ctttcagtag
      841 agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat aacctgtttc
      901 ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag ctacatcttt
      961 gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt gaattgactc
     1021 attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca ttttttcttc
     1081 ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac ttttaataga
     1141 taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga caatactagt
     1201 aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag aaattttccc
     1261 catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt taaatgcttc
     1321 gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca aaagataatg
     1381 ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca acatgcatat
     1441 tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg ctttctataa
     1501 caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt gagatgccga
     1561 tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc agcttgtctt
     1621 ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt gtttcagttg
     1681 catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta atataatttt
     1741 caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga tcaatcagct
     1801 gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg tcgatattaa
     1861 ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga tacaacttgc
     1921 tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca gtcattcgaa
     1981 taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt gctgcatact
     2041 tttcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta gcattatcta
     2101 aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg ttttcgatat
     2161 tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt tcctgatact
     2221 gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga ataaacaaac
     2281 tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa taatttggat
     2341 tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt ttccatttag
     2401 aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa gaataattgt
     2461 aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga atcaatgtag
     2521 catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt ttttcgtttt
     2581 ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat atatttttaa
     2641 cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg gagcgatcct
     2701 ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca ttaaggtttt
     2761 cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata cgattatatg
     2821 tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt tctttttcaa
     2881 tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata aaaaaaatca
     2941 atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa agtcctcatt
     3001 ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg taaacgcttt
     3061 gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat tctattgtag
     3121 aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa ccaagtgggt
     3181 ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag ggttattagg
     3241 aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt tatggttatt
     3301 tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt tcagaatttc
     3361 atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg aaaatttcaa
     3421 atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg tttataacgt
     3481 tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc tgagccaaat
     3541 ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta attttttatc
     3601 atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag gattaattaa
     3661 tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac cgaagtactg
     3721 gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat ccatcattta
     3781 ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag ttgatggtgc
     3841 cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga ttattgtcat
     3901 tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt tttatcaatt
     3961 gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt atgtctaccg
     4021 tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat atcagtcatc
     4081 agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag atcctagttc
     4141 agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat gtacttttcg
     4201 ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag ctgtattttt
     4261 ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca actcaacggt
     4321 tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat acaagatggc
     4381 ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg aacgttgatt
     4441 actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt cccttaccgg
     4501 aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat ggttccttct
     4561 tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt gattctacct
     4621 cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa gtcgattcca
     4681 gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt ttttttccaa
     4741 atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc aagcttaggt
     4801 tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt gattccattg
     4861 caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa taatgacatt
     4921 acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac acgaatggca
     4981 atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca aaaatacttt
     5041 gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga tgttaaaaga
     5101 tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc cttggcctat
     5161 taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc acaaaagtta
     5221 cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca aaagtcaacg
     5281 aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg gacggggatt
     5341 atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt tgtttcgtca
     5401 atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc aacgatcatt
     5461 tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt gaaggtgggg
     5521 caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca acggaatatt
     5581 ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat gttgaaggtg
     5641 tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat acgaatatta
     5701 cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt atcggtggtg
     5761 gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat acttatgaga
     5821 ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa ggatatattt
     5881 tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa aactggtttt
     5941 taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa gctctagcgg
     6001 gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga tttgcaagag
     6061 tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg aaattgttga
     6121 attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt gaaggaaaac
     6181 actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat tattatcaag
     6241 gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt acagaagaaa
     6301 gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg tctcctattt
     6361 taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta caaaatatcg
     6421 tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa tatgtaccag
     6481 agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct gctcaagaac
     6541 aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa gaatagacta
     6601 agcagttagt ggggggattc aaatgaacga aaacaaatgg accaaaggat ttaattgggt
     6661 ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag gatttggaat
     6721 tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc gaaaaaaata
     6781 tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt ttgttagata
     6841 taatctatat tgctggtcag caactttgtt gttggccggc aatattacta cgatctggct
     6901 ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat cggtaattac
     6961 actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg ggttgtggat
     7021 gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc caacggtagt
     7081 catgcaaggc ttggtgcttg gaatttattt ccgaatattg atgattttgc ctgtgatttt
     7141 tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg aaagagcgtt
     7201 agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg agtatttctt
     7261 tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca acttgagatt
     7321 ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac aaaggctaat
     7381 gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tttgcttgtc ttattcacat
     7441 gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc tcaaggagga
     7501 gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt agatgcttct
     7561 cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt agcgttgatg
     7621 gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga ccttccatat
     7681 tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt tgaatttgct
     7741 tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt gacccaattt
     7801 ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact gatcggtgaa
     7861 gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat gtatcagaca
     7921 gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg atatttaagc
     7981 ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg tgtgttatca
     8041 attgttgata aatataagat gaaaccaatg atttggagtg atttcattta taagctatta
     8101 gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc attagcagct
     8161 aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga tgaagtttcc
     8221 tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca ttacgtttta
     8281 gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac agaagcaatt
     8341 gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat gttaactact
     8401 tggggagatg aagggcagga aacagagcat tggcattcct taattggggc attaaaatta
     8461 gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta cgatcgttta
     8521 ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga agtggatacc
     8581 attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg gcaagatccg
     8641 ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac tagaacaatt
     8701 ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg gaatccaaaa
     8761 caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat tttagcacaa
     8821 aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct tgcaggatta
     8881 atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt ggcatctatt
     8941 catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt agaacaacga
     9001 tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa tcatcttcag
     9061 gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca atatcaagtg
     9121 ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta caattaacga
     9181 aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt tcgttttcta
     9241 ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta ggaagtgaga
     9301 aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata cagaaccatt
     9361 acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt tagaaaggga
     9421 aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt atccttctgt
     9481 ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg atagaatttc
     9541 tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca atgtatctta
     9601 tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg tatatcggcg
     9661 tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag gagcagatag
     9721 taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga gtcatagtac
     9781 atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc aaattctagt
     9841 gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa tgagcggtct
     9901 atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt atcaactacg
     9961 gacgttgact gatcctaaaa aaggaagcgg aacattaatg gtttcttttc aacgatttac
    10021 tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg gacgtctcat
    10081 agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag attgcctttt
    10141 ttggacagca gaaacgccta aattatatac attactttta acatgtaatg gtgaatattt
    10201 taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat tgctgaacgg
    10261 aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag gcacgccagt
    10321 gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa atgtgaatac
    10381 tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg atgagattgg
    10441 tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc tatatgatac
    10501 tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga ttatggaccg
    10561 agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt ggtctatggg
    10621 gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac ggaaattgga
    10681 tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc aagtgaatga
    10741 ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg ttcatcgtca
    10801 ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc acgctatggg
    10861 caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg attcctttct
    10921 tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt tagaaacgcc
    10981 atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt tttgcgtaga
    11041 tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc gtaatattca
    11101 ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct tgagcaatat
    11161 aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata tagatggaaa
    11221 aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa gttgttcatt
    11281 gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt cgctatctgt
    11341 ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag aaaaaatgag
    11401 attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag gcacagagct
    11461 gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg cgttcacttc
    11521 tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa tttggcgtgc
    11581 accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat atgctgaaat
    11641 gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc tgatcgaaac
    11701 gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca tacagttgaa
    11761 aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc cgatttttcc
    11821 agatttccct cgctttggga tggactggcc gttgaatgat actttttcga aggtttctta
    11881 ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga tgtttggtat
    11941 ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag aatatggtaa
    12001 ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca tgacggttta
    12061 tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg aaaagtcaca
    12121 ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata aacaaaatgg
    12181 tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta tggaagatac
    12241 ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga aacaaagatc
    12301 aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa ccattgctta
    12361 aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg tttcgaacag
    12421 ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca gctcataaat
    12481 gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca tttgaaaaat
    12541 gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc agcaaacctt
    12601 cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt aggagatcaa
    12661 ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg aggaatcatt
    12721 gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt ttcatatatg
    12781 aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt attacgtaaa
    12841 aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct tttatctgct
    12901 gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga tattgatatt
    12961 acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat tgagcttggc
    13021 gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg tgctgctaaa
    13081 cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt agaggaatat
    13141 cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata tgataatcgt
    13201 catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt accgttcttt
    13261 tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca ggaaatggct
    13321 tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga ttatttagag
    13381 gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct ttctaaggag
    13441 agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc ttcaaagttt
    13501 acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc tttggaaact
    13561 tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta tcttacctta
    13621 accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga attactgcta
    13681 gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc agtaaaatgg
    13741 atccagcaag aacaacatac atctagattg agaacagaat tggagccttg gttacaagca
    13801 atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc aaaagaagca
    13861 gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt aactgcccat
    13921 ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa aaaggagaac
    13981 aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat gacgtcaaaa
    14041 gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga aacggttgct
    14101 aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc atttggtgca
    14161 gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg actaccaaat
    14221 gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat tcctaaatta
    14281 aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc taaaacaaat
    14341 atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga aacgatacaa
    14401 aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg cactggagta
    14461 accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc gggattgatt
    14521 attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa agaggcgatt
    14581 atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg gtctatccca
    14641 ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata tgatttgtta
    14701 acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt gcggcaatta
    14761 gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc tggatacggg
    14821 ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg aatgcgacat
    14881 accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa aaatggttaa
    14941 attgattatt taagtgggaa catacttgag atatcagcta acttctgtca ctttaaaaaa
    15001 gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact aggatagcag
    15061 aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct cttattgttc
    15121 ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta ggaaaaatgg
    15181 tagggaacca tatcattttt aatgaaaatc aagcatttca aaagttgaaa aacgttgatt
    15241 tatcggcatt ccccatccat attatattta cgtcttattc ccactccact gttgcaggtg
    15301 gtttgctggt aatatcatac acgatacggt taacgtgtgc gacttcattt acgatacgga
    15361 cactgatttt ttgcaagact tcccaaggga tacgggcaaa gtcagcggtc atgccgtcaa
    15421 tagaagtgac agcacggata cctacagtgt agtcatacgt acggccatct cccataaccc
    15481 caacagagcg aatgcctggt aggacggtga agtattgcca gatgtcgcga tctaaaccgg
    15541 cattggcgat ttcttcgcgc aagatagcgt ctgattcacg gacgatttct aatttttctt
    15601 ctgtcaattc accaaggaca cgaataccta agcctggtcc agggaatggt tggcgccaaa
    15661 cgatgctgtc aggcatgcct aattgggtac ctaattcacg tacttcgtct ttgaacaatg
    15721 tgttcaatgg ctcgatcagc ttgaattgca tgtcttcagg taatccacct acattgtgat
    15781 gtgatttgat ggtttgggca gtttcagttc ctgattcgat cacatcggta taaagggttc
    15841 cttgtgcaag gaaagaaacg ccttcttcac cggcaagttt ggttgcttca tcatcgaaga
    15901 catatacaaa ttcatttcca atgattttac gtttttcttc tggatcagac acgccagcaa
    15961 gttttgataa gaaacgttct ttggcatcga cttttataat gttcaagcca aattttccgc
    16021 caagactttc cataacttgt tctgcttcac ctttacgcaa caatacgtga tcaacgaaga
    16081 tacatgttaa ttgatcgccg atcgcttttt gtaaaagaac accaacaaca gaggaatcta
    16141 ctccgcctga aaggcctaat aaaacttttt tgtcaccgac ttgttcacga atttttgcga
    16201 tctccatgtc gatgaagtta tccattgtcc agtcaccagt acattggcag acatctagtg
    16261 taaaatggcg caacaagtca tttccatatt cggaatggcg aacttctgca tggaattgga
    16321 ttccgtacat tttgcgttct gcattttgga tcgatgcgat ggggcaatct ttgctggtag
    16381 caacgacatc gaaatcagtc ggtgcttggg taactaggtc accatgactc atccaaacgg
    16441 tttgtttttc aggagtgttt tggaaaaggg ccgcttctgc agaagtgatt tccaattctg
    16501 cttttccgta ttcacggttt ttggctggtt taacagaatt aggcagaagt cgcccatcct
    16561 ctataggtgg gtgatgaatg ccgttcggta tgagggt
//
LOCUS       DAPBCF010000056        15939 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.057, whole genome shotgun sequence.
ACCESSION   DAPBCF010000056 DAPBCF010000000
VERSION     DAPBCF010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15939
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.057"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(173..475)
                     /locus_tag="RD508_002258"
     CDS             complement(173..475)
                     /locus_tag="RD508_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736800.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(695..1061)
                     /gene="ssrA"
                     /locus_tag="RD508_002259"
     tmRNA           complement(695..1061)
                     /gene="ssrA"
                     /locus_tag="RD508_002259"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1232..2005)
                     /locus_tag="RD508_002260"
     CDS             complement(1232..2005)
                     /locus_tag="RD508_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7736801.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2149..2499
                     /locus_tag="RD508_002261"
     CDS             2149..2499
                     /locus_tag="RD508_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDT7736802.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2480..3196
                     /locus_tag="RD508_002262"
     CDS             2480..3196
                     /locus_tag="RD508_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7736803.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3196..4644
                     /locus_tag="RD508_002263"
     CDS             3196..4644
                     /locus_tag="RD508_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7736804.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4714..5223)
                     /locus_tag="RD508_002264"
     CDS             complement(4714..5223)
                     /locus_tag="RD508_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736805.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5213..5938)
                     /locus_tag="RD508_002265"
     CDS             complement(5213..5938)
                     /locus_tag="RD508_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736806.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(6161..8281)
                     /locus_tag="RD508_002266"
     CDS             complement(6161..8281)
                     /locus_tag="RD508_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDT7736807.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            8511..9689
                     /locus_tag="RD508_002267"
     CDS             8511..9689
                     /locus_tag="RD508_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HDT7736808.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            9705..10463
                     /gene="aroD"
                     /locus_tag="RD508_002268"
     CDS             9705..10463
                     /gene="aroD"
                     /locus_tag="RD508_002268"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDT7736809.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            10486..10971
                     /gene="ybaK"
                     /locus_tag="RD508_002269"
     CDS             10486..10971
                     /gene="ybaK"
                     /locus_tag="RD508_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HDT7736810.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(11042..12295)
                     /locus_tag="RD508_002270"
     CDS             complement(11042..12295)
                     /locus_tag="RD508_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7736811.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            12412..13761
                     /gene="gdhA"
                     /locus_tag="RD508_002271"
     CDS             12412..13761
                     /gene="gdhA"
                     /locus_tag="RD508_002271"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HDT7736812.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            13873..15219
                     /locus_tag="RD508_002272"
     CDS             13873..15219
                     /locus_tag="RD508_002272"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDT7736813.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(15527..15913)
                     /locus_tag="RD508_002273"
     CDS             complement(15527..15913)
                     /locus_tag="RD508_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7736814.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         5217 a         2844 c         3191 g         4687 t
ORIGIN      
        1 cttataattg gagtggtagt taattagtga cttatttttg attttatagc actgatacta
       61 taaaatatag atatcatcat attacacaat cttaatacta acttaaaaaa tatccctttt
      121 ataagtatgg tgataaaatc cgttccgggc tacctttttt aggtagccta ctttaatctt
      181 tatacctttc tggatcaacg aaagtatact tcaaatagtc ataacgccga tgatcgctcc
      241 gtgcgtctgg cacatcagtc acgatatcaa acaaaaaata cacatctttc ttcattctgg
      301 tttttgttgc cggaatttta aagtagttct tattagagta atagagattg attaataagc
      361 tatcttcgat tgctaaaaag aaaacttctg aatcccacac cttataaaaa tctttgacaa
      421 atctattcga aggatcaaat ttaaaccata attgtgtttt tccttccatc aacataatgt
      481 tcacctcaaa aagagtatac gaactaatgt tctttttgta aagtaggaat atcattgata
      541 atatggatgg aacatatata ttaaaaagtg ttctttttga atgctatttt gaatgccatt
      601 ttcattcatt taacgaaaat ctgcgaaaat aaaaaatgct caaaccctta taaaataagg
      661 atttaagcat ctagcgaaat ctgctgaaat ctcacaatgg agacggcggg agtcgaaccc
      721 gcgtccaaac acatcgccac ttaaaaatct acgttcatag tcaactcatt taaggattca
      781 ctttacagct tgccgagtga caggcattct gtatcgctag tctgatgttc tctttttcaa
      841 cttacagacg gaaagttgaa acgtatccca ctaaagttag gacccttact cgagcacatg
      901 ggcgatgccg agaggatcta cgctaactgt ttttaggcag ctaaagcgta agagttgttt
      961 tcgtttttag cagttatatt taactgtaac gtttttacgt agacgtaacc tacgaaacgc
     1021 aattcaagct cgactgtgcc tgtcgaatcc gtaacgtccc cgttagctaa caagggttac
     1081 gtgtattttt catacaaaat tagtatagca tatattggga taaattcaat aaaaaagcga
     1141 atcatatccc attatttata taataactgc ccctttctta agaaaaaata agcgattttc
     1201 ttaagaaaag aggtagcttc aaaaaaagat cttaaatcag atcaaaatac ttcaatgcgt
     1261 ggacaattcc gccttctgta tttttctttg tgataaaggt agaaagttct tttaatccgt
     1321 cataggcgtt gcccatagcg attttgttgt cgcaagcttc caacaaggca aaatcattcg
     1381 gaccatcgcc aaatccaaaa gtaggaactt tttccagctg aagttctttt tgcagacgtt
     1441 tgacacctgc cccttttgag attcctttct tcactgtatc gatcgagtaa ggaccattcc
     1501 gataaaaagt tagctcagga aaatgttcgt gatagtattc gtcacctgat tgagataaga
     1561 tcagcaacat atttactgtg ttttctttaa agcctaaagg atcaatttcc ggaacatctg
     1621 aatgaatgaa gtcgtaagca ttgatcattg tttggctatg accggtacac cagattttct
     1681 gatcgttata gtaagaaagt tcatgaccgt tcaactgtac atgatcatac attttttgac
     1741 attcttctga agaaaatgtt tgagaataga tttcttcgcc gtctactcga atgaaagaac
     1801 cattcatggt gaccgcagaa gtaatgcccg catcttccat gatagagtgg atttctgctt
     1861 ctgtacgtcc tgtagcgatg acggggagaa cattgttttc ttttaatgcg ttcatagctt
     1921 ttgccacttc gggtgtgatt tttgatttcg catctagtaa tgttccatca agatcaaaga
     1981 aagtgattgc acgataattt gacacaaata aaactccttt tttattggaa taagtttatc
     2041 ttaacaaaga atgaacaaaa gacaaacctt tcgtgaagaa ttcctgaaca tattggttca
     2101 gtcaacaatt tagagtatac tataagaaga gaatttagga gggaaagaat gatttttttc
     2161 agtattggta tcttattctt aataattggc agtctttttc ggattctgcc ctcaaaagga
     2221 aatctgcctt tttatgggta tcattcgcct cttgccgcaa aaacagacgc tcattggcgg
     2281 ctggctcaaa agacaagcgg aaactggttt tttcttatgg gcttactgat ggcattgatc
     2341 ggctattatt taaagacatc tgggcatacg aattattttc tgattgaaat gcttctgcta
     2401 gtatttccaa ttatgcctat ttttattatg acagaaaaga aattacagaa atatgacctg
     2461 gaaactggag ggaacgataa tgaatatttt aatgattgaa gataatcaat ctgtttctga
     2521 aatgatgcag atgtttttct taaatgaagg ttgggaagca actttcaagt atgatggaaa
     2581 agaagggctc gatgcctttt tagaaaaccc acaacattgg gatatgatta cactagacct
     2641 gaatttgccc acactggacg gtatgctagt aggaagagag atccgcaaag tttcaagtac
     2701 tgtgccgatt atcatgctga cagctagaga ttctgaaagc gatcaggtga tcggcttaga
     2761 gatgggggca gatgattatg tcacaaaacc tttcagtcct ctgacgctta ttgctcgaat
     2821 gaaagctttg catcgccgta gtgagttggc agaagcaaga gaagaagcag tagtttcaga
     2881 tgatcatttt gatatcgaga ctagtcattt caagatgaat acgaaaacac gagaagcgta
     2941 tctggacaac cggccaattg aaggactgac gcctaaagag ttcgatctat tgtttacttt
     3001 agcaaaaaaa ccacgtcaag tattctctcg ggagcagttg cttgaattag tctgggatta
     3061 tcagtacttt ggtgatgaac ggacagtgga cgcccatatc aagaaattac gacaaaaaat
     3121 cgaaaaggtc ggaccacaag tcatccaaac tgtttgggga gtcggctaca aattcgatga
     3181 ttctggtgtt gcctaatgcg ttatttgtat cagcaactct tagctttctg cggaatggtc
     3241 gcgttgatct tattgatcgt tggagtttct tttacacaac tgacaaaaca aacgattgaa
     3301 gaaaacaatt accagcaact gtttggatat gctgaatcag ttgaaaagac aacgcaaacc
     3361 tatgccgata cgctcccgca gtttagtcaa gatcaggcgt ttcaaaatgc attgctgctg
     3421 acagagcaag tactgacaga acaaaatgtg aactttatat ttatcgataa aaacgaacgt
     3481 gtcatttatc cgactaatac agctttactg aattttacct taacagctga tcaatggaaa
     3541 aatctgagga atggacgtca agaaaaattc acatcgaata aaaatatttt aggacaagca
     3601 caggcgacct cttacgcact tgtgccattt aatttgaatc atgaattcta tggagcactt
     3661 gtagttagtc aacctgcgcg aaatatcgat aacagcgttc gtccaattac actgaacctg
     3721 ttcaaaggat ttattttttc cagtatcgtt gcagttattg ccagctatgc ttttgcagca
     3781 ttccaagtta agcgtatcaa tcggttaagg aatgcgacga aagaagtgac gaatggtaat
     3841 tttgatgtac agctccccgt acatgacaaa gatgaatttg atgagttagc agatgatttc
     3901 aataaaatga cgaattcatt gaaagaatct caagcagaaa ttgaagaaca agaaaatcgt
     3961 cgaagacaat ttatggcaga tgcttctcac gagatgagaa cacctcttac gacaatcaac
     4021 ggacttctgg aagggttaga atacaatgca atccctgaaa atcagcgaga aaacgcgatt
     4081 aaattgatga aaaatgaaac agagcgtctg atccgtttgg tgaatgaaaa cttggattat
     4141 gaaaaaatcc gtacgaatca aatcagtatg gtcattaaaa aattcaatgg aacagaaaca
     4201 ttgaaaaata ttgttgcaca gttagaagct aaagcagaag cagcaggaga tacattgaca
     4261 ttgaaagccg ttgatgatat tgatgtttac gctgattatg accgatttgt ccaaatcatg
     4321 gtcaatatta ttcaaaacgc gatacagttt actgaaaacg gccaaatcac gattacttta
     4381 gaaaaaggct atcttgaaac gatcatcacg attgaagata cgggaattgg aatgtctgaa
     4441 caacaaatga aaagtatctg ggatcgttat tataaagtag atccttcaag aaaaaataca
     4501 aaatatggtg aatcaggatt aggtttacca atcgtgcagc aacttgtacg cttgcataaa
     4561 ggaaaattag aagtagaaag cgaactagga aaaggaacaa aattcgctgt tcgtttgcct
     4621 gacgtagaaa tcaaaaaaga gtaaaaaaca agcggtataa aagatcatga atcgatcttc
     4681 tataccgctt gtttttacta taaaatgatt gatttagccc gcgggctcta aacgatcaat
     4741 ataaggactt tgagcaatag tagcatcatg agtaaagagt aagatacctt gattttcttc
     4801 atgagctaaa taagaaagca agtggagtag ctcttggatc tccaatacac taagttcatc
     4861 aaatgtatct tcaataacaa tattgtttcg cttggaaagc aaggcatgaa gtaattgcag
     4921 ctttactttt tcaaaagacg tcaactcagc tgccgcacaa ttaagcaagg aaggagagat
     4981 atcaagtttt tcttgatagg ccaaacgatc ttgtttgatt tctttttccg gtacatccaa
     5041 caggacatgg tctttaagat tcagataagg aaacatcggc caattttttt ggatgatcgc
     5101 aaaattatcc agttttgcaa caagaacctc ttttttcaag tgctccaata ttttatgctg
     5161 tttttcgaga ggacacaaaa taacggtcaa gtgttcagca tgaatcaaat attcaggttt
     5221 cattacgtcc aggcctccta ctttgcaaat gatggataaa aaaagtgaaa gggaatagac
     5281 taagaatgag acagcatcca ctgagcccaa taagagtttg ggcaaatccc ttaagtatat
     5341 ctgtgaaaaa aagatcattt tggaaatcga tggtaaaaaa agtctgttga tccatcggaa
     5401 ttgtaagtcc gcttaccgaa gtcaagatat cacggatatc tggcagttca gtagtcttta
     5461 agacaagaaa attgatcctt tgaagaagcg cttcataaac tgactggaag cttacgatcc
     5521 acaataaaac caagatacaa caaagaaaga gaggaaagaa cagctgccag aaaataaaaa
     5581 ggaataattt ggttttagaa agaccagtca ggtgccaatt gatcaattcc tgcttgtttt
     5641 gcctgactga atagtaaaag aaaaagataa aaaggaaggc aaatagaaaa aataaactga
     5701 atatgccttt tatataaaat cggctagcta attctaaagc cggaagaagc tctgtagatg
     5761 cagaagcgcc aataaatgaa agccgatctt ggacttgatt ggctaaagcc gattgcaaat
     5821 ggtaaagagt caggcatgct atcaataaaa aagcagaaaa gcttgaaaat aaacaataga
     5881 gtattgtctg ctttttgtaa taaattaatc gagcagtagc atagcggatt attttcatac
     5941 ttttcacctc tataaaaagt atagaaaatg aatatgaata aagtatgaaa ttcctttagt
     6001 gaaatcacga attaaaacca gaaaatattt tgtaaaaagc aagaggttgt gaagaagctg
     6061 ccctattcta ttaccgtaga tgcaagcttt tgaacactgt ttattcgaaa agaggagcag
     6121 cgacaataat tttgtcgctg ctccttttaa atttatttta tcattcggaa gaacttgtgg
     6181 tcgttccgtg aagttcttgg tacgtttgcg ttttataaag atcaacagtt gattgtccgt
     6241 tgtgttcact aaagacacta gttgacttgt caccaagaga tttttcagct tcttttaatt
     6301 tctctaagcc attcttgtag tcataatcac tggtatcaat tggatctaat ccactattcg
     6361 tatagaaccg aagaagatca ccattattga tttggtcaga aacagctaac tgtttatcaa
     6421 ctttttcttt cagtgaatca atttcattct gtacttcctc agtaggttca gtaatagctt
     6481 caccagtttc gttactatag atcgtaccac cgtagtaagt atattttggt gtaacaaaat
     6541 caccatcacg gaaagaaaca agctgttcat gatctttcga gaatagatct tgtcctaact
     6601 gaatataatt ttttgtatct acacctagta agtgaagtaa tgtaggcaag gcatcaactt
     6661 gtccgccgta agtgtgattg attccgccct gtgtttgtcc agggatatgg atcatataag
     6721 ggacacgctg catttgtgca ttgtcgtagt ttgtccaagt agaacttgtt tttccaacta
     6781 attcagctag atttttattt cttgaattcg agacaccgta atggtcaccg taaaggacga
     6841 tgactgaatt atcatacaag ccgctttctt tcaaataatt gaagaattct tgtacggcgg
     6901 tatctaaata attggctgtc gcaaagtaac cgttgatcgt ttcatcattt gtattggcta
     6961 acgggaatcc tgcttcgtca ttggtgaatt ttgaataagg ataatggtta gatacagcaa
     7021 tgaattttga ataaaatggt tgttgcagac gttccaagta ttgtacggat tgttggaaaa
     7081 atggtttatc atgcaacccg tattggaacg aattgtcatc attaacatca taataagaag
     7141 aatcaaagaa ataatcatat cctaaattct tgtatgtctc gtttcgattc cagaatgtac
     7201 cagcgttccc atggaatacc gcactaatgt aaccttgtgt ttgacttaaa atatcaggtg
     7261 cagcttggaa agtatttttt ccgcctaatt gtgtgaacaa ggagccttga ttcaagccaa
     7321 acaatgaatt ttccatcagc gtttccgcat cgcttgtttt tcctgctttt acttgatgga
     7381 aaaagttgtc aaaactgaac gtgctgttgc tgtggtaaag actattgatg aaaggtgtaa
     7441 cttcatgctg gagaccattc tcatctgtca atttataatc gatcaggaat tgctggaagc
     7501 tttctaaatg gatataaatc acattttttc ctctagcgag cccgaacaaa tcgtcatttg
     7561 gtgctgcata atgttctttt acataatttt ctacttcttt catatcattg ggacttgctt
     7621 ctgcccgcac ttggtttgtc tggtaagttt gaacaccgtc ataaaccatg aaagcattca
     7681 agccaagata tttgaccaaa taatcacgag agaatgttcg agtcagcaat tctggacgat
     7741 cagcttccgc cataaaaaga tttcctgaga aaatcataac tgctaatgta gagatcgcaa
     7801 aagccattct tgctcggatc gggcgagggt ccaacttgat tttttttgca atcagcagaa
     7861 cagtcaagat aataaaatcg atccaataga tcacatcata tgggcgaaac agtcgaatgg
     7921 cactttctcc cagaccactc gctactttcc cagcacctaa aatcgtgttg atcgtaatga
     7981 agtccgtgaa ttctcgataa taagtgacat tcgaaaaaac aagcaatgtc aaaagaaaat
     8041 aaatgaccat catcgtgata taagcaactc tagggcgtct gatataaaga gcaattccaa
     8101 gtaataacaa tgtagttgca atagggttga taaacaagat aaagtattga atgccacttt
     8161 cgattccgag atggaaatca actaaatagg caaaaatcgt tttcaaccaa agtaaaacga
     8221 ctagtaaaga aaaaaatccg agcctcttat tcaaaaaggc aggtgttttt atacatttca
     8281 agataatctt cctttctgca cttcttaatc acagaagtgt cctgaaacca tgttacacag
     8341 ctcacttatt ctcatttatt ttactagtat gacaatatag tgtcaattga aaccagaagt
     8401 ttatgctgtt tcattaaggt tttctttaag cttcatgaaa aaatgagcag taagacaagt
     8461 cctatgtttt ttgttatact tgggaagaga aagctaaagc aggtgaagga atgaaagtaa
     8521 aagtaaaaaa aagagcaagc aatcgattga aaaaaggata tccactgatc caaaaagaag
     8581 accttgctca tccccaaaaa gaaaccacgc aatgggtgga attagttgat tcgcaaaacc
     8641 aatttatcgc aaaaggatat ctaggaaagc agaataaggg aatcggttgg gtattgagcc
     8701 agcagaacat cccatttgat caatcttttt ttgaagaatt ttttgtgaag tcaaaagaaa
     8761 aaagaacttt ctttttttca gatgattcta ctaccgcttt tcgtatattc aatggagaag
     8821 gagacgggat cggcggtctg attgttgatt attatgcagg ttatgctgtt ttttcttggt
     8881 ataacgaaac gttatatgca catcgtgaat tattgattca agcttttcgt gaaatctacc
     8941 cggaaatcat aggaggctat gagaaaattc gatttgaatc agtaaatctg cctgagagcc
     9001 agttcattta cggaaaagag gcaccggaac ccttgatcgt aaaagaaaac ggagtaaaat
     9061 ttgccgttta tttaaatgaa ggattaatga ctgggatctt tttagaccaa aaagaagtac
     9121 ggggatcatt agcagaaggt ttcgcttctg ggaaaacagt tttgaacatg tttagttata
     9181 ccggcgcctt ttctgttgct gccgcaatgg gaggggcaat cgaaacaaca agtgtcgatc
     9241 tagcaaaacg cagtttaaaa aaaacacagg aacagtttga agtgaatggt ttggatgtcg
     9301 atcagcaaaa aatcattgtt atggacgtat tcgagtattt caaatacgcc aaaagaaaac
     9361 aatttttata tgacatgatt gtattggatc caccaagttt tgccagaaat aagaaaaaag
     9421 tctttcgcgt agcaaaagat tatggggaac tggtcaagga tagtctggat attttagcag
     9481 aagacgggat acttattgcg tctacaaatg ctgcgaatgt ctcgatagaa caattccaaa
     9541 caatgattga agaggaattc catgccaaaa atgtttcttt tgaacaactt gctttatatc
     9601 gtctgccaaa agatttccag acgacggata cctttttaga aggcaattat ctgaaagtgt
     9661 ttgtttatca aattaaaaat aaccattaga aggagcgatg cagaatggtt cgggtaaagg
     9721 gattgaatat aggaagcggt agaccaaaga tttgtgcgcc tcttatcggg gccgtccgag
     9781 aggaagtatt acgtgaagca gttcttgcac gtgaagcagg ggccgattta gtcgaatggc
     9841 gagtcgatca ttatcgtgaa gttttttctt ttgatgaagt agcagaaaca ttggttctta
     9901 tccatgagat gcttgatgga ctgccgttat tatttacgtt tcgtacctta gctgaaggcg
     9961 gagaacaaga catatcgatc cgtcagtatc gcgaccttta tgaacatgtg atacacacag
    10021 gattagtaga tatggtcgat atcgagttgt tcaaagtaga aagtctagga aaaagactga
    10081 tagaggaaat caagtcttta aacattcctt taattatcag tagtcatgat tttaaagaaa
    10141 caccagcaga ccctgtcttg ctttaccgat tgaatgttat ggaacatttt ggagccgata
    10201 tcggaaaact ggcagtaact cccaataatg aacgagatgt tttgcggttg atggagttga
    10261 ctagacgggc aaatgctttt gtctccatgc ctattattac gatgtccatg ggaaatcttg
    10321 gtaaaatttc tcgtctggtt ggcggaacga cgggttccgt tatgacattt ggttccttaa
    10381 gcagcgattc tacttctgct ccaggacaat taccggtcaa agcattgaag caaattattc
    10441 aattattaaa tgaaccgttg tagaacaagt ttgaggtgat attttttggc aaagaaaaaa
    10501 atagtaaaaa cgaatgcaat ccgtatggtc gaacaaaaaa agattcccta tacagagcac
    10561 gaatatgagt gggacgaaag ccacctaagt gcgtcatcgg tcgctgaaca gcttccagaa
    10621 agccaatctc gtatatttaa aacactggtt gctgtgggca atgtgacggg gcctcttgtt
    10681 gctgtgatac cgggagaagc cgaattgaat ctaaaaaaat tagcaaaagt ttcagggaat
    10741 aaaaaagtag aaatgctcca tttaaaagat ttggaagcaa cgaccggata catacgtggt
    10801 ggctgctcgc ctataggtat gaaaaaacta tttcctactt atttagatca aattgcagaa
    10861 agctatgaac aaatcattgt ctcggctggc agaagagggc tacagatgga gttagcacct
    10921 caagatatct gtgcattaac gagcggacaa tttgcagata taaaacaata aatcatacgt
    10981 ataaaagaaa gaaggaggcc gggatgttgt ttgtccagtc tccttctttc ttttttatac
    11041 attatgctct ttgcccggca ttcattcctg ctacatgccc tgtagcgaaa gccgctgtga
    11101 tattaaagcc gccagtataa ccattgacat ccagtaattc tcccgcaaaa tacagaccat
    11161 caatgatttt actctccaat gttttaggat aaatttcctt tagagaaacc cctccgccag
    11221 ttacaaatga tttctcaata ggaaaagttt tgttgattga tagcttaaac tctttgcata
    11281 gttgaacaaa atcttgaatt tgtttttgag aggcttgttg tcctgtcaga tgatccattt
    11341 caagccgctc aagaaagaaa actaacaatc gctcaggcaa tataccatgc caagcattga
    11401 ccaagttctt tttggttgct ttactttttt ctgtcaatat atgaataagc tcttgtttgg
    11461 tttgtgtagg gaaacaatcc agagaaagtg tcactggttc tcccgttttc tctaattctt
    11521 tattgacaaa acttgaacaa cgcagtgcag ccggaccaga aataccgaaa tgggtgaaaa
    11581 gtaaatccat cgtatgttca gtcaatacac gacctttttt atttaaaacg cgtaaagtga
    11641 tgtcttgtaa agaaagccct tgaagtgttt tctcctgaat atacggttca tccgatatca
    11701 agggggactc tgtcgcataa agaggcgtca ccgtgtgacc cactcgcttc acgatcttgt
    11761 acccatctcc agtagaacca gtagatggat aagtccgtcc accagttgtt aagataatgg
    11821 caggagcatg gaactcttcg aattccgtgc gtataccgta aattttatgt tctttgtgga
    11881 tcaatttctc tactcgagta gagaatagaa gcgtcacatc tagttctttc agacgattga
    11941 gcaatgcttc gataatcgtt tttgatttat ttgttacagg aaacatccgt ccatgatcct
    12001 cttcttttaa atgtacgcct tgtgattcaa agaagttcat gatatcgaaa ttattccatt
    12061 gcgcaaacgt actatataaa aactttccat ttccaggaat atgtgcaatc aaatcatcaa
    12121 caggacgatt gttcgtaaca ttgcaccgac caccacctgt catcagtagt ttttttcctg
    12181 cttttttgtt tttttcgatc aagagtacgc gtgcgccttg ttcagctgca ctgatcgctg
    12241 ccatcatccc gcttgttcca gcgccgacta cgatcacatc atacagtttt tccattccct
    12301 cacctcaagg aaagtgtagc atatctgaag aaagaaaaca gaaaaaaatg ttttgagcca
    12361 aaagagaaaa tgagctaaaa tgagggaaga taagcaaagg agcgtggaac gatgacaaac
    12421 gcaacagaat atgttcaagc aattcaagaa aagctacatc aaaaggatca agggcaagaa
    12481 gaatttttac aagcaatcga tgaattcatg cccacggtta tgtctttttt ggacactcat
    12541 cccgaatata tcgaaaagaa tatcttagaa cttttaacgg aaccagaaag agttattcaa
    12601 tttcgagtgc cttggcaaga tgatgaagga aactggcgag taaatagagg gtaccgtatc
    12661 caatacaact cagctatcgg cccttataaa ggtggattgc gcttccatcc tagtgtcaat
    12721 ctaagtatct tgaaattttt ggcttttgaa cagattttca agaatagttt aaccggtctg
    12781 ccaatcggtg gaggaaaagg cggaagtgac ttcgatccta aaggaaaatc tgataatgag
    12841 atcatgcgtt tttgtcaaag tttcatgctg gaattgtcaa aacatatcgg cccatcgatt
    12901 gatgttcctg cgggagatat cggtgtagga gctagagaaa tcggctattt gttcggcgaa
    12961 tataaacgat tgaaaaaata tgatactggt gtgttgacag gtaaaccttt ggatttttgg
    13021 ggaagtaaga tacgtacgga agctactggt tatggattag tgtattatgt caaacatcta
    13081 ttgaacgaag aaaaagattc atttaatcaa aaaacagttt ttgtttccgg aagcgggaat
    13141 gtagccattt atgcaatcga aaaagtgcaa gagctaggcg ggaaagttgt tacatgttca
    13201 gattctagcg ggtacatcta tgatccagaa ggaatagatg tgaaactatt gaaagaagtc
    13261 aaagaaatca atagacaacg tttgacggaa tacgcaaacc aacgtccttc tgctatttat
    13321 catgctggag aatctgtttg gacattgaaa gaaaaagcgg atatcgcttt gccatgtgct
    13381 actcaaaatg aaatagacga aagcttggcc gaaatcttag tagaaaatgg gatcaaaatc
    13441 gtagcagaag gcgctaatat gccatgtaca gtaaaagctg tttctgttct tcatgaagca
    13501 ggcgtgtggt attgtccagg aaaagctgct aatgctggag gagtagcagt atctgcttta
    13561 gaaatgagtc agaacgtcca gcgattgact tgggaaagag agcaagtgga tgagcagctg
    13621 gatcaaatca tggaaacgat ttaccatacg tgtcgccaaa cagcagccga gtacggcgac
    13681 gaaaaaaatc tgcttcttgg agcaaatgtt gctggatttg aaaaagttgc caaagcaatg
    13741 gcagcagaag gtttagtttg aaaaatgaaa ctttcttgga aatattgtca gcattttgtt
    13801 tatttgcttg aaaaataata aaaaaaaacg taaagtatta cctgtagagt aaacctataa
    13861 ggaggagaac aaatggcaca cattcatttt gactattcaa aagtagcacc gtttgtcaac
    13921 gaacaagagt tagggtacat gcaaagccaa gtaacagcag cccacaacga attacgggaa
    13981 ggtactggcg caggaagcga cttccgcggc tggatcgatt taccaacgaa ctatgacaaa
    14041 gaagaatttg cacgtatcaa agaagcagct aaaaaaatcc aatctgattc tgaagtatta
    14101 gttgttatcg gtatcggtgg ttcttattta ggcgctcgtg cagcgatcga cttcttgaat
    14161 cacacattct tcaatttatt agatagcaac acaagaaaag caccacaaat cttctttgcc
    14221 ggaaattcaa tcagctcaac atatattgct gacttgatcg aagtaatcgg tgatcgcgac
    14281 ttttcagtaa acgttatttc aaaatctgga acaactactg aaccagcgat tgcgttccgt
    14341 gtattcaaag agcttcttgt taagaaatat ggacaagaag aagcaaacaa acgtatctac
    14401 gctacaacag ataaagcaaa aggtgcagtt aaagtagaag cagatgcaga aggttgggaa
    14461 actttcgtga ttcctgatga catcggcgga cgtttctctg tattaactgc tgttggtttg
    14521 ttaccaatcg ctgttagtgg tgcagatatc gatgcattga tgcaaggtgc cgctgatgca
    14581 agcaaagcat actcaagcga caaactagaa gaaaacgaag cttaccaata cgcagcaatg
    14641 cgcaacattc tttaccgtaa aggcaaagta actgagttgt tgatcaacta tgaaccagga
    14701 atgcaatact tctcagaatg gtggaaacaa ttgtatggtg aatctgaagg aaaagaccaa
    14761 aaaggcatct atccttcaag cgcaaacttc tcaactgatt tgcactcttt aggacaattc
    14821 atccaagaag gacgtcgcaa tatttttgaa acagttgtga aggttgaaaa acctcgtaaa
    14881 tcaatcacaa ttcctgaaca agcagaagat ttagacggtc taggctactt gcaaggaaaa
    14941 gaagtggact tcgtaaatac aaaagcattt gaaggaacat tgcttgctca tacagacggt
    15001 gacgtgccta acttgctagt caaaattcca gaaatggatg cttatacatt gggttataca
    15061 atgtacttct ttgaaattgc tgtaggtatt tcaggttact tgaatggaat caacccattc
    15121 gaccaaccag gtgtagaagc ttacaagaaa aacatgttcg cacttctagg caaaccaggc
    15181 tttgaagatc ttgctaaaga attgaacgaa cgcctgtaag ataagggttt ttcgctagat
    15241 ttaaataatc agtgatagaa acatgttcgc tttaaaatga aaactggtac ccatttaggt
    15301 actcaaacat actgcatcgt ttattcagaa taaggggctg tgacaagacg tttgtcacag
    15361 tcccttgttt gtatagaaat cgattgattg ccttgctctt tagtttgttt taggacttta
    15421 agaacagtga ggctgacttc gaaggttaat tctgtttttt tgttttctag aatcagtaag
    15481 caaaaaagca ctcacttcga gtgctttttt gcgatatatt cttagcttaa gataggccta
    15541 atttttcttt tacagatgag ggtaccttat cgctggtaat tacttttttc tctatgatcc
    15601 gcttttcgct tgctttcaac tgcaagatcg ttccttcggg gtaagcagaa ccattggcag
    15661 agtcaccaga agtaatgaca tcgaaatcta actgtctttt ttcaccgttt tcagcataag
    15721 catctacgtt gtatttaaaa cctcttccaa ttacttcccc attatctgct ttgatatcag
    15781 tttctgcagg cattggagct ttgactaccg cataataatc tttacctaca taagtagact
    15841 gatagtagtc ccaacctttc catcctataa aagcaatcaa tatgataacg atcaacccta
    15901 aaattttttt catgaaagat ctcctttttt atttttatt
//
LOCUS       DAPBCF010000057        14764 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.058, whole genome shotgun sequence.
ACCESSION   DAPBCF010000057 DAPBCF010000000
VERSION     DAPBCF010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14764
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.058"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            4..2376
                     /locus_tag="RD508_002274"
     CDS             4..2376
                     /locus_tag="RD508_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736815.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLARLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSSEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="RD508_002275"
     CDS             2437..3897
                     /locus_tag="RD508_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HDT7736816.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEMKVEPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKGCERVDGKYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VRKDWNDQLKHEIQQQEIRKQKRAMLFQQNRQQERE"
     gene            3908..6112
                     /gene="topB"
                     /locus_tag="RD508_002276"
     CDS             3908..6112
                     /gene="topB"
                     /locus_tag="RD508_002276"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDT7736817.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLENLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGVPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPVDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIEILKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPRCQEQEVILYQKVAACTSEVCDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6128..6277
                     /locus_tag="RD508_002277"
     CDS             6128..6277
                     /locus_tag="RD508_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736818.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6352..6945
                     /locus_tag="RD508_002278"
     CDS             6352..6945
                     /locus_tag="RD508_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HDT7736819.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6958..7857
                     /locus_tag="RD508_002279"
     CDS             6958..7857
                     /locus_tag="RD508_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HDT7736820.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTILKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7860..8345
                     /gene="ssb"
                     /locus_tag="RD508_002280"
     CDS             7860..8345
                     /gene="ssb"
                     /locus_tag="RD508_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDT7736821.1"
                     /translation="MINNVTLVGRLTKDPDLCYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMANLARKGSLTGITGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDVATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            8713..8973
                     /locus_tag="RD508_002281"
     CDS             8713..8973
                     /locus_tag="RD508_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736822.1"
                     /translation="MNNYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9414..9620
                     /locus_tag="RD508_002282"
     CDS             9414..9620
                     /locus_tag="RD508_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HDT7736823.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9620..9871
                     /locus_tag="RD508_002283"
     CDS             9620..9871
                     /locus_tag="RD508_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736824.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            9886..10323
                     /locus_tag="RD508_002284"
     CDS             9886..10323
                     /locus_tag="RD508_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736825.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFESIEKNGAFYTIESEEKDNE"
     gene            10316..11023
                     /locus_tag="RD508_002285"
     CDS             10316..11023
                     /locus_tag="RD508_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736826.1"
                     /translation="MNKVVYQLTTEDVSQFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGK"
     gene            11404..11583
                     /locus_tag="RD508_002286"
     CDS             11404..11583
                     /locus_tag="RD508_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736827.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11924..12187
                     /locus_tag="RD508_002287"
     CDS             11924..12187
                     /locus_tag="RD508_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HDT7736828.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12181..12531
                     /locus_tag="RD508_002288"
     CDS             12181..12531
                     /locus_tag="RD508_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDT7736829.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12555..13169)
                     /locus_tag="RD508_002289"
     CDS             complement(12555..13169)
                     /locus_tag="RD508_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7736830.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDVFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            13618..14076
                     /locus_tag="RD508_002290"
                     /pseudo
     CDS             13618..14076
                     /locus_tag="RD508_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
     gene            complement(14161..14418)
                     /locus_tag="RD508_002291"
     CDS             complement(14161..14418)
                     /locus_tag="RD508_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HDT7736831.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(14411..14680)
                     /locus_tag="RD508_002292"
     CDS             complement(14411..14680)
                     /locus_tag="RD508_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDT7736832.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
BASE COUNT         5406 a         2452 c         2954 g         3952 t
ORIGIN      
        1 gacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ttagcacgat tgcaaaatga actaaacgaa caaatcgaaa agatgtttga acaccaaaga
      121 aagaccaacg gtcaaccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gaacgtttag aaaacaaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacag
      241 gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgataa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgccacgatc cgaaaatatc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 ggctatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctgca
      661 ccaactgatt ctctgaagga gaaagaaaaa gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt agaattgatc
      781 gatcaactta aaacgttgga taaccaatac gctgcagaag caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagta gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaccccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat caaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttcttctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaaggat tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctacacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tgtagaaacg gcagaacaaa agaatattgt tcctgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccacagcata atcaagtaat tttaaaagga
     2221 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 tcattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagacta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac cctaagcaac aatttaaagc agccactgat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgagacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gctgaactaa agccaaaaca tgaacggcaa aatttcttag ttcgagacga tcgtttggat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaaag agacagtagg ggcgagttat
     3001 caaggaacat ttattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggatttaac ctaaagatcg gtgaccctaa acagttaaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     3181 gatacgtggt tagtctctat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccattga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagttgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aagtcattta tgaagaagtt gcaaaagaaa tgaaagttga acctgaagca
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaact ggtttccgct
     3541 cacaaagtaa atgcgtcttt tggtcagcag ctttctgtta acgattcaat agaagctatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aaggttgtga acgcgtggat
     3661 ggtaagtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc tcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggttataaaa atcatgaaca tgaatttgta
     3781 cctgaagtga gaaaagattg gaacgatcaa ttgaagcatg agatccagca acaagaaatc
     3841 agaaaacaaa aacgtgccat gttgtttcaa caaaacagac aacaagaaag ggagtgaaat
     3901 cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca caagcgaaag cttatgccga
     3961 tagcttctct aaagccaccc gaaaagacgg gtattttgaa atccaagatc gattgtttcc
     4021 tggtgaaact gtgatcacgt atggttttgg tcatttagtc gagttagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agagaatttg cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatcgcttg
     4261 gacgatcatt caacaagcag gcgccgatca tggaaagata tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcaa ttacgagacg cagaagagac
     4381 ctatcccaaa tttgaagaag cacaagcacg ccagatcgct gattggttga tcggcatgaa
     4441 cggcagccca ctgtatagtt tactcttgca gcaaaaaggc gtaccaggaa gtttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcag ctgcaggaaa agattagaaa
     4561 cttccaaaaa gagccttatt ttgaaggaaa agcccaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggtacg atccaccaag ttgaaaccga
     4741 gaaaaaaagt gcggcaagtc cacgtctttt ttctctatcc agccttcaat ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagatac tttggaagcc atgcaagggt tgtatgaagg
     4861 gaaatatcta agctacccac gaacagatac cccttatatt acagaagggg agtatgcgta
     4921 tctgttggat cacttagacg aatacaaaca ctttttaaag gccgaagcca ttcctactcc
     4981 tattcataca ccgaatagtc gatatgtgaa taataagaaa gtccaggaac attacgcgat
     5041 cattcctaca aagacggtca tgacggcagc ggcttttgaa caattaagtc cactgcagca
     5101 ggccatttat gaacaagtgt taaaaacaac ggtggccatg tttgcggaaa aatataccta
     5161 tgaagaaaca acgatcttga cgcaagttca gcagcttcag ttaaaagcaa tcggaaaagt
     5221 gccggtagat ctaggttgga agaagttatt tggaaaagag agcgacggaa aagagaagga
     5281 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtag atctacaagt
     5341 ccttgaaaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcgat
     5401 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtaga
     5461 aggaatcggt acagaagcga cacgggcaaa tattattgaa atcttgaaac aaaaggaata
     5521 tatcaaggta gagaaaaata agctcgtggt gacgaataaa gggattttgc tttgccaagc
     5581 cgtggaaaaa gagccgctgc ttacgagcgc cgaaatgacc gccaaatggg aaagctactt
     5641 attaaagatt ggagaacgaa aaggaacaca aaccactttt ctagctaata tccaaaaatt
     5701 tgtctctcac ttattggaag tcgtaccagg gcaaatccaa tccactgatt ttggatcgac
     5761 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     5821 tccaagatgc caggaacaag aagtcatact ttatcaaaag gtggcagcat gtacgtctga
     5881 agtctgtgat tttaaattat ggacaacgat tgccaaaaag aaactcacag cgacacagct
     5941 gaaggagatt attcaaaata gccgaacaag ccaaccagtg aaagggttaa aaggtcagaa
     6001 gggttcgttt gaagcaacga ttgttttaaa agaagacttc actacaggct ttgaattttc
     6061 tgaaaagaaa aaaacgaact tcaagaaaag aacacgacgc actacaaaat aatggagggt
     6121 taatcttatg cgtaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagccaaaat
     6181 tcgttcagaa caggaaaaaa tgcgtgccag caaacgaaga ctgcagcaat taaagaacca
     6241 gcagcggatt caaaaagaaa ttgaattaga tcgatagaca ttaaccttgt tacaaataca
     6301 ctatcatgat atatttaatg tagtgtattt gtaacaaaag gggggaagta aatgcaagag
     6361 aaactgaaag aattgttggc tattcgcgat ggaaatttat ctatgaagga agccagaaaa
     6421 ttaggaatcg cagcaaccac tgtacaaaga ttggtgaatc aaggaaaatt gatcaaagtt
     6481 gatcgtggtt attatgtaga ggatggtcat ggaatagatg atttattttg gcttcagcaa
     6541 cgattttcca ggggaatctt ctctcatgaa acgactttag atatttacca gctttctacg
     6601 aatatgccga aattcattca cttaactttt ccccatggat ataacgttga tcgttcaatt
     6661 acaaaagagc agcagttaca atttcatttc gtgaagaaag aagtttatga actaggaaaa
     6721 gtagagggaa cttcctttca aggaaatcct attactatgt atgataaaga gcgtacactt
     6781 tgtgatattt ggaatccgag atatgaaatt gaatatgaaa tgaaattaga agcattaaaa
     6841 gagtacatgg aagacccatt gagagatcca agtaaattaa gagattacat gacaaaacta
     6901 catgtagaaa aagaaatgaa ataccacatg caaagcttat attgatggag gaaaaagatg
     6961 acaccgacac aatttgcagc aaaaacaaga aatttagcaa agagtacagg attaaatgca
     7021 cagttagtgc aacggcattt tatgatggat cgtctaattg aacaaatttc tgaatcaaag
     7081 tacaaaaatg acttcatttt gaaaggcggc tttttattag gatcaaaata tggaatcgat
     7141 agaaggacaa caattgatat cgatacgaca tttagaaata gcaaattaac tgaagaaaaa
     7201 ttgaagagca tttttaatga tttaactaga aaacccacaa aagaaggcat tgttttctct
     7261 attcaaggaa tgaaggaaac aagagaagcc gatttttatc ctggatttca aattaaattg
     7321 gtggctaatt tagagaaagt acgtgtaccg tttaaaatgg acgtgacaac aggagattct
     7381 atttatcctg aagtagatac acactatcac caattaatgt ttgaagataa aaaagtggag
     7441 attccagctt atccaacaga acaaattatt gcagaaaagc taagtgctac gttcagcttt
     7501 ggcacagata attcgagagc aaaagattac tacgacttat ttaccattct gaaactagaa
     7561 aatatcgata cgaaagagtt atacaaaagt gttcgaaata catttacaaa acgtggagat
     7621 acaaagcctt tatcctttta ttatgaaaga gaaatggata agatcagggg aaacgactat
     7681 ttggaaaagc agtgggaaaa atatcgctca gttaacacgt ttgcgaattc catttcattt
     7741 acagatacag tcaacgaaat tgatcaccta atgaaaagtg tgatcaaaat tgaaaatcaa
     7801 gaaagaaaaa ggcagtttaa aagatcacaa caaatgaatc aagaaatgga gagataaaga
     7861 tgattaataa tgtaacttta gtaggacggt taaccaaaga tccagattta tgttataccg
     7921 caagtggcac agcagtggct acttttaccc tagccgttaa tcgtaatttc acgaatcaaa
     7981 acggcaatcg agaagctgat tttatcaact gtgtgatttg gcgtaaacct gcagaaacca
     8041 tggcaaactt agctagaaaa ggtagtttaa caggaattac aggacggatt caaacacgaa
     8101 cttatgacaa ccagcaagga caacgggtgt acgtaacaga agttgtggcc gataacttcc
     8161 aattattaga aagcaaagca gcaacagaaa gccgtatgca cgctgatcaa tcgtccagca
     8221 gtccaagtcc taccaccttt gaacaacggg atgtagctac gcctaacaac aatggattga
     8281 atgcttcaca gaatccattt ggtggacaat caatcgatat tagcgatgat gatctaccgt
     8341 tctaagtaga atattctatt gtatcggttg catttgtgac taattatgat ataatcaagg
     8401 taacaaaaaa caggttcata ttacgaccga aaaccactag cgggctggct agtggttttc
     8461 ttttacgttc ttttcagatt aacgggtagg cttactgtct tttttggcaa ttttgcaatc
     8521 aagccatttg cagatatagt gggctgctac ttctgccgca attgcaaaaa taaaatcaaa
     8581 aaacagactc attaattacg acctcctccc cttgccagat taggccgggg tagcagacag
     8641 caaaactatt atagcataat tgaaatatcc aaatgatttg atttttgcta taattttatc
     8701 gaggtgattg tgatgaacaa ctatgttggt ttgcttgata aaatccgagt aataaaaacg
     8761 caaccgttat tggttcgctt tactttacaa acgattcatg aatcgattaa ttgtgtagtt
     8821 gcagatattg aaattatcga taaattgcta attatggatg atggaaaata caatattgcc
     8881 gtcacaggtc acttcaataa acgaaatcag ctagttattg ctagcatgta tgttagaaat
     8941 cccgatcatt ttacgcgatc gatgggcata taaataaaag aagagttgta gtcctaaatg
     9001 aggattgcag ctctttttgt tttacataga aacaggaaaa gaccttttta ggaagacaca
     9061 agtgccttct caattgaaaa acctttctct cactccaacc gccaccgccg ttcgagaaga
     9121 aaggaagtga acgctgcacg ttcactaaga tatggtgtct tgcaaagcaa gacaaaatag
     9181 acaaaacttc ctctcaccaa aaggttcgtt cctgttcgtt atctctttat tgatttgcca
     9241 gaccggcaac aagttgcctt ttatcaccaa aaagcgacaa ggacaagggt aaatggcacg
     9301 ctgcgcgccc ttgtccttgt cgcttttcgt tgatttattc tggccaacaa atcaataaag
     9361 aaagaactaa cgaaaggaag taaaaccttt cctaagagga ggcagaatca aacatgcgaa
     9421 agaaatttga ttattggggt gttcccttca gcgaattatt cccaaactat catgcaccac
     9481 atactgttga atgcgattgt ggagaaagag cgaaatgtat caaaagctat cgtttgtatc
     9541 aatgtccaac atgcgggaaa aaatatacct tgtcttatgg cgattacatt ttgattgatg
     9601 agaaaggaaa gaaacgctga tgaaaacaca acacaaatta ttgactgtaa aagaagtcgt
     9661 tcaaattttg gtggacaaag aagtcatttc tgaaaaagta gcagaagctt tacttattcc
     9721 gcggtactgg acgatagaaa cccctttagt agaggatgca ccgactatgc tatttgaaga
     9781 cctagtgaag attgcaggat atgaactgca ttatcaagaa aacatggaaa cttatgaaat
     9841 cgaatattgg ttaaccaaat tagagaacta aaaaggagaa aaaatatggc tcaaaattac
     9901 tatgacgaat ttgtcaaatt acctttggat aaaatggcac aaaaaatgga ggatatgacg
     9961 ttcctatacc atgaaacacg tgtacccaaa aaacattaca aggaaaaatt gtcagtcgca
    10021 gtggaagaaa tgattgaatc aggtgtcgaa atgaatctca ttgcgacgta ctatcgaaca
    10081 ctggaagaac tgaaaaaaca aaatggaaaa tggtttttcc aagccttact atgcttggaa
    10141 gtaggtgtca aaccaagcac tatcaaacct tccgaatatc aagccttaga actgacttat
    10201 gcaaaattcg cacagattaa gaaagctaaa gcaatggcta gcgactggct agatactttt
    10261 gaaagtatcg aaaaaaatgg tgcattttat acgattgaat cggaggagaa agataatgaa
    10321 taaggtggtt tatcagctaa caacagaaga tgtttcgcaa tttttaacaa acaaagaaca
    10381 cttgaatgaa gtaatcagac ggattcaaaa agactttagt tgtatggaag aaatgaagta
    10441 ctttattcaa agagtggaag aacagttgta tatggaaagc gaaacaagtc aaacgaaggt
    10501 cacagtcagc cataatcatt tagacgtgta taaacgtcgt cctgaaacgg taaaaaaagg
    10561 aacagagctt ctacgactag aaacagaaaa atacatcatg aatgtgtacc tagaaaggag
    10621 tgagctggtc gaaaactttg tcagctacac gatttgtagg aaacactatt actcagaatc
    10681 agaatattat tcaattttcg agagcatgga attaatggaa gaagaaatgg aagagctaaa
    10741 cagcaaaaat gcgacggtag acgattatta ccttgtattt actaggtttt tgacgtgtgg
    10801 gacggaatct atcgtgttaa tgggaatgga ttatgaactc gctgtacccg aagcattttt
    10861 gagggaatat gtagaagaag tagataaccc aggcgacgac tggtacacga ctttaactga
    10921 ttttttagac acctacactt acgacgatac agaagaaatc caaaatgaac ttgaccgtaa
    10981 acgaatgcca tatcaacgat ttgaaaggaa aaaaggtaaa taaccattta taccgaaaag
    11041 tgaggatgtg tgaaataaga acaaaaaacc ttgaaattaa gggaatggtt cttatttcgc
    11101 accaatcgct ccaaccgccc ccgccgctta ggtggtgcga aataagcggg caaagcccga
    11161 taacctaaga gaaagaagga gatccatatg aataaaatca ttcctctatt gttcgtactg
    11221 tttgttggcg agatacttat gcgtcatgct gcagctgtac atttaaactt cgtagtattc
    11281 ttaggaatac tggtattttg tttgatcttt tggcgatttg tattagccct tgtgagtcta
    11341 ctattcaaga tgattgcagc catatttttc atagggttat ttcgatgaaa ggagagagta
    11401 ctaatgccaa ttgcaatagg aaataaacgg ttacccgtga cattagatga aaagagacaa
    11461 aaagaattgc agcaactaaa gcagaagtac ggaaaaagtg aatctaagat tatgtgtatt
    11521 gcgttagatc tattgatcgc gcaagaaaaa gcaggatttg atataccagc actaaaaaag
    11581 tgacgtcact tttcatttga agaaacaaaa gtgatagcac ttaattgttc ctactattta
    11641 gaatattttc tatgtccttt ttattccatt ttgtatcaat aactatgaaa tctttaaagt
    11701 atccagaaga gattattttt agatcaattt ttttcttacc tgattctaaa gattttgttt
    11761 tcttaaacat attatgattt cctttcgact attttcatat aaatgttaac atagtttatg
    11821 gattcatgga atgttaatct aatttaatag aaaaggataa ttaagtatat acgttttttc
    11881 ttatgtatgt tatactatgt atatacagaa agaggtgtct actatggaaa tgttacctat
    11941 aaaaaaatgg ggaaatagta atggccttag attgccaaag tatattatgg aatatcttgg
    12001 aattcataca gaagacaaag tgaagataat acaagaagaa gtaaacggtc agaagcggct
    12061 aattatcgaa gcggctaata tagaaaatga attaacaatt gaacagttat ttgaaaatta
    12121 cactgatgaa agaaatcatg tgacgattca aaatttaggt gaagcagtag gtaatgaaaa
    12181 atggtgagaa aacctagaca aggcgatatt ctattattga atacagcacc tcgatctgga
    12241 cacgaacaga caggtaaaag accttatatt gttttaagtc atgatattat tgcggattat
    12301 agtaacgttg ttacagttgc tccaatttct agtacaacta gaaactatcc gctatatgta
    12361 aatataaact cagaatatga aatgaagaca acaggaaaag tattattaga tcaactaacg
    12421 acaattgatt atgaagccag agagtgtatt tttttggaaa aagcgcatga tagtttagtt
    12481 gaggagttat tgatgaaagt tagaacagtt tttcaaaaag taagcaaata aaatagaaac
    12541 agcagcatga tcaactattc gtgattgacc atgctgtctt tttttattct atatacggtt
    12601 tgtctcgtaa cattgtagtc ttttgcaatc ttagcgatcg caacaccttt ttttagatcc
    12661 tcaacgatgt ttttataaac aagacgacgt tggggatctt ttgcattggc actgtatagc
    12721 ttaggacgtc ctttataaac accgttcgct tttgcaatct taatgccttg tgcctgacgt
    12781 cgtttagatt cggtacgttc ttgttcagcg atcatggcca aaatttgaat gatcaaatct
    12841 ttaatgaatt tatccaggag aggattgcca attgcttcgg ccatgatcgg tagacttgtg
    12901 atgatcagct gcacattttt cttcttcaag taattgactg aagcgatgat ctcgtcgtaa
    12961 tttcttccaa gtcgatcaat agcttccaca ataaaaacat cttgatctcg gacgaaatcc
    13021 agtgcttctt gaaaaacagg tcgatgagta atcgttgcgc cagattgttt ctcaatgaaa
    13081 attctctctg caccgaattt tttcatttct tcaatctgcc gttgttcatt ttgatcgatg
    13141 gatgagacac gtatgtatgc aactctcaaa atttttacct actttctgca actatttaaa
    13201 aaacacccta atcatacacg agaaaaccag atttttcaat gtcgcggtcg tgtctagtta
    13261 gggtatacct tatatagaca aaaactaatg atggaggaaa tagtatgaga attttttgta
    13321 agtgtctact gataacttat tctcaaatgt tgtaaggatt ttattcattt gttaatatta
    13381 aagaacggaa ctccaaaaaa gtccgtactc taatttgcgg tctctcactc ttttagagtg
    13441 agagttttta ttagattttc aaattaatta gtaaagtgat agaataaatt gatcatacaa
    13501 atcaaaagaa gaagcagggt gatagcatac ctatgcttct tttttatgta tttagctatt
    13561 tcttctttac aatatcgaac atatgtttgt ataatgtgaa agaatggagt gttatttatg
    13621 atggattatt caaaagagcc agtaaatgat tactttttaa tcgatatgaa aagcttttac
    13681 gcaagtgtcg aatgtataga aagaaactta gatccattaa caacagaact tgttgttatg
    13741 agtcgtgctg acaacactgg atcagggttg attttagctt cttcaccagc tgcaaagaag
    13801 aagtacggta tttctaatgt cagcagacca cgggatctac cacagccttt tcctaaaacg
    13861 ttacatgtcg ttccaccacg catgaatctc tatattaagc gaaacatgca ggtaaacaat
    13921 attttcagaa ggtatgtagc agacgaagat ttattgatct attcgatcga tgaatcgatc
    13981 ttaaaagtga ccagatcact gaatcttttt acgactgaag gaacaagaag tcagcgcagg
    14041 cagaaacttg ctcaaatgat ccaggaacat attaaatgaa ttgctaagaa acgtaatgta
    14101 atgaaaaaaa tagaggtcaa aaacttaaaa gtttctgacc cttcccttac ttccaattgg
    14161 ttaatagtga tcttttgcag aataaataaa tatcgtttca ttttcaactc tatatatcag
    14221 tctatgttca tctgtaattc ttctggacca ctttccagat aaatcatgct ttaatggctc
    14281 aggttttcct aatccagcaa agggagaacg atcgatatct tttattaact tgttaatctt
    14341 ttttatattg cttttgtttc cttgctcatg ccaataaaga taatcatccc aagcatcatc
    14401 agaccaagcc ttaatcatca gattcaacct cgattaagtc atgtgtttta aatgcacctt
    14461 tggagaattg ttcatctcct cgacgaattt tttccatgac gtaattatta gaaagtgttc
    14521 tcaacgtttc ttgcatagaa tcataatctc tttttgataa tacaacaact gtatcttcta
    14581 catctttact tgttacaata agtgtttcag catcctcatt aacttgtttc atataactac
    14641 gtaaattttg gcggaaattt gaataagcta ctgcttccat tcctttcacc ccttatttat
    14701 ttctataaaa caattgtaca ttatattgta caattaagca aatgattaat attctaactt
    14761 ctta
//
LOCUS       DAPBCF010000058        14753 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.059, whole genome shotgun sequence.
ACCESSION   DAPBCF010000058 DAPBCF010000000
VERSION     DAPBCF010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14753
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.059"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..152)
                     /locus_tag="RD508_002293"
     CDS             complement(<1..152)
                     /locus_tag="RD508_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7736833.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWV"
     gene            235..384
                     /locus_tag="RD508_002294"
     CDS             235..384
                     /locus_tag="RD508_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit S"
                     /protein_id="HDT7736834.1"
                     /translation="MKAIINSKDYEGYKAKHPEAKPFKYPQEMKRAWRKMLDDELIPL
                     ENELR"
     gene            complement(1133..1746)
                     /locus_tag="RD508_002295"
                     /pseudo
     CDS             complement(1133..1746)
                     /locus_tag="RD508_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406632.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(2967..3671)
                     /locus_tag="RD508_002296"
     CDS             complement(2967..3671)
                     /locus_tag="RD508_002296"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012610.1,HMM:NF019322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7736835.1"
                     /translation="MIFDKVKEQIRKVYITTDRKSELLPSERDLAQEFSVSRPTIRKA
                     LASLEDEGIISKNEGRGYLVKPASEKYVDHELDSFIGFFQDAVQQGKKISSKIIQQTI
                     IPADSTISECLEIEQNTLVLVLERIRYIDDYPTCIAKSCIPLSVLPEIVEHDFAKESL
                     FSVLESRGIRLAYAKRSIEVTPPTDLENLYLDLEKNEPVFVFTSIGFAKNQKPFEYEI
                     SKYPAYKTKFESTVSK"
     gene            complement(3686..4555)
                     /locus_tag="RD508_002297"
     CDS             complement(3686..4555)
                     /locus_tag="RD508_002297"
                     /inference="COORDINATES: protein motif:HMM:NF012585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDT7736836.1"
                     /translation="MKIAVICSGGDSPGMNSALLAIKKTIDSEPDSEVVFFKNGYAGI
                     FKECIASVSLKEVEVFKAGTLIGTARFEKMRDLESRKIIIENLNKMEIDNLIVIGGNG
                     SLKGAELLKNESELQVSVIPGTIDNDFPNTDYTLGFDSALNTIIRSIDDLTSTANAHD
                     RIIIMEVMGRGCFALPEYASIANNTYWVERDDKEYLHLICKKFESEFYSPILLLPEGI
                     SNKQKIIEFITKNLPKETKYLNLAYLQRGSSPTFYDRYIGYLWGQLAAKELIEGKSGI
                     LSQKNGNIMLIPW"
     gene            complement(4663..5679)
                     /locus_tag="RD508_002298"
     CDS             complement(4663..5679)
                     /locus_tag="RD508_002298"
                     /inference="COORDINATES: protein motif:HMM:NF013539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7736837.1"
                     /translation="MFNFDQERFLKTQAGAVATNEQISNILESIASDLEEIYFIGSGG
                     VGILFDSTIEFARTRSTFPFHRVIAAEFMIHPNKTFSNKSLVVIPSLSGTTKETLELV
                     EYCNEMNVKTLALVGSPKTPLEKAATYSIYNDVLDDTSSENYYLQGLLIALFLMKQRN
                     EIDINQYNTYIEDLKKIPEALVHAKEQAEPMAKSFAKKHKDTSYHILTGAGDSFAEAY
                     YYGMCILEEMQWIKTRPVHAADFFHGTLELIEAGVSVIITEGEDDSRPLTERVKNFVP
                     KFTDVHVTVDTKDYDLPGISEDTRKIISPVVLATVFERISAFLEEERNHPLTTRRYYK
                     QMEY"
     gene            5869..8592
                     /locus_tag="RD508_002299"
     CDS             5869..8592
                     /locus_tag="RD508_002299"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012385.1,HMM:NF013070.1,HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7736838.1"
                     /translation="MKTKILKELNDLLNSYDFPQYFPEECNAQYIAQKFQIKRNTASK
                     HLNELMEQKKVVKINGRPVLFFPVHTIERYISHSLDSFEFSSIDSFREKISKKKADHF
                     FDDLIGAKQSLKEAVQQGISAMKYPGGLPIMYFGSSGVGKSYLVEKLAEYCRQTGIIH
                     ENAPFIELNCAQYFNNPELLTSQLFGHMKGSFTGADSDHIGIIEAADGGIVFLDEIHR
                     LPPEGQEKLFIHMDKGVFRRVGDSGPWRLSHVRYIFATTEQEENFFLETFRRRIPIVC
                     TLPNYQDREISERKEIVFHLLEKESTLINKEILVSEAALSFLIRLDLYGNIGELDGLI
                     KQTIANKLFSGSNKKYIEIHISDLPSRYLLTENIELKNQIASQRFYIFSNGNYVHDCD
                     ETSTVTTNLRGLIHRVSKYYSECHDVNRNSEEFRRFVKDQMAEFNDRFIYQKNSEVLV
                     KYYLPEIQNIVQKISPSLFVHLSGNTVQAIATYLAIRDQWGYGKENASANEIEKLYEN
                     LKCNYLTDLNVFLLIFENALDTTLTIWDKLYISLCVISETGNEAKDINAIILAHGYAT
                     ASSIANVANRLVNQFVIDSIDMPLDISFSEVIDRLLHYIEYRKSKNGLVIFVDMGSLA
                     QIKTEIEQVIEVPTMIINNVTTEMAIETAQLIQSTSDIQKVVKKLPYSQFEKQVLYPI
                     KIRKRTIVVSCNTGLGTSIKIKEMMENNLSKDLGIEFLPYENETLRDTQQLEFLIKTK
                     DIIAIIGTDDPRVSNIPYISLEELFDGEIGKLYKVLLRVYGKEIAEAINQNIVKNSSL
                     NRLIDSLTILDAEKVVNQIEESLKDYQMRVGKTLSSLSKINLYVHISCMIERLIRNQG
                     VSSYPAIDQFLKRYETEVASIQKALSKIEKLYNIKIPMEEIAYVCNIIVSY"
     gene            8720..9142
                     /locus_tag="RD508_002300"
     CDS             8720..9142
                     /locus_tag="RD508_002300"
                     /inference="COORDINATES: protein motif:HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose IIA subunit"
                     /protein_id="HDT7736839.1"
                     /translation="MRQILCMSHGPLAKGMIETLSIIVGDLDNIDFRCAYVDGNNDVE
                     MIIDDYLKESMGNETIVVTDIFGGSINNEWLRRLPDLSKVYLISGMNLSLLVDLYLKF
                     QLVSSDQIEEIIDHAIQASSGSIKFCNQLDYEQTVDDF"
     gene            9160..9630
                     /locus_tag="RD508_002301"
     CDS             9160..9630
                     /locus_tag="RD508_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7736840.1"
                     /translation="MIKLVRIDHRLIHGQVALTWTNAISADCILVANDEILNDPIQKT
                     TLKLAAPHNVKVVIKSIQDSIDAINSGKTDKYKLFVVTKTISDAKRLANGVEQIKSVN
                     IGSVKETSGSSALTHTIFVTEEERAELKGMVSEGIEVFAQQVPTDKAIDLKKSL"
     gene            9654..10436
                     /locus_tag="RD508_002302"
     CDS             9654..10436
                     /locus_tag="RD508_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017867004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7736841.1"
                     /translation="MDSLLVQAILLGLLTAFIVIDWMTGTNNLSRPIVSSVFVGLIMG
                     DLKMGIMMGATLELAFIGAITIGAARPPDTVSGGILGTAFAIATGKGAEFALTLAFPI
                     AALFLLVDNLLTLLVLPMIARKADRYAEKGELKNVSKMHVLGFILVKSLPRALFVGFS
                     FYLGSPVMERILNAIPTFVQDGINIAAGIMPALGFAILLQMLLKKDVFVYFVIGFALF
                     SYLHVPILGIAIFGACLAYIIVNMETKAAMGSRGEEMVEDDF"
     gene            10420..11250
                     /locus_tag="RD508_002303"
     CDS             10420..11250
                     /locus_tag="RD508_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014093338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7736842.1"
                     /translation="MKMTSSGKALTKDDLTKICIRSCALEASWNFERQQHMGFAFAMM
                     PALEKIYSGNEEEKQKAAQRHLEFFNTAPPLSTFIMGIVASMEEENAKNPDDFDTSTI
                     TSIKTALMGPLAGIGDSMFWGTLLVIGIGVGASLAKEGNILGPFLFLLIFNVPNFLLR
                     YFGVMQGYNFGTKLLENIESSGVMKTLTHAASILGLMVIGGMSGSMVSIKVAGSIGQG
                     DEATKIQSIIDGILPNLLSVLCVFLIYWMLKKGFKTTYVLFGIFIFGIIAAFFGFLTT
                     "
     gene            11285..12283
                     /locus_tag="RD508_002304"
     CDS             11285..12283
                     /locus_tag="RD508_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017867002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7736843.1"
                     /translation="MLNYNAKEMKKKGKRIYGIREDVEKIAKQAYDSGISNIFFTASG
                     GSVAVMQPFEYVLMTESSIPVYSMTAAELVLMGHKQLNEKSLVILYSKSGDTKETIKA
                     AEYLKERNVPTVGIVSKEDTPLEALSTYAINYLDGRPQEMPLYFLIMSIMNLNGEFPE
                     YTRFADELKNLPTALNSVREQADEKGKKYAEEFKEDPYQIWIGSGNLWGITYSYSMCV
                     LEESQWLRTKSVSSPEFFHGTLELVEKGVCVTLLKTEGETRLLDARVEKFAVQYTDKF
                     NVFDTKDYELPGISDEFRKYFCAPVMWAALGRVSVHLEDIRNHSLDKRRYYRVVEY"
     gene            12300..13154
                     /locus_tag="RD508_002305"
     CDS             12300..13154
                     /locus_tag="RD508_002305"
                     /inference="COORDINATES: protein motif:HMM:NF012515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736844.1"
                     /translation="MTAYVIGFGDNVVDYYENLNQKFPGGNAVNFAVNAKKSGVKAYY
                     VGSLSSDPDGVLLQHAISSEGVDISFSEVIDEPTEQAHVTIKDGDREFIGGVRGSRLT
                     PALSAELIDLMKNSSLVHTSCHSRTETKIKELKKYDVKVSFDFSDLDKYRTHEYLSDV
                     CPSIYIAQFSVATDDQEEINRLISECKDFEVPYLLFTRGSKSPVFVDTRENKTYEGFI
                     RKVESPHDTMGAGDAYFAAFASNFVLSKREKSMIEHVIDCFHKGANLAYETLMIDGSF
                     GHATPINP"
     gene            complement(13728..14753)
                     /locus_tag="RD508_002306"
                     /pseudo
     CDS             complement(13728..14753)
                     /locus_tag="RD508_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS110 family transposase"
BASE COUNT         4724 a         2331 c         2839 g         4859 t
ORIGIN      
        1 acccaacgat aaatcgtagt atgacaaaca tttattccac gatcatataa caattcctga
       61 acttcacgat agcttagatt gtaacgcagg tagtaaccaa cagcgacaat aatgacgtct
      121 tttttgaatt gtttgccttt aaaatgattc attactctgt cctctctgtc ttttttctca
      181 attttacact aaaatagatt ttttggaaaa ctttgcaaca gaaccatttc taatatgaaa
      241 gcaattatca acagtaagga ttacgaagga tataaagcca aacatccaga agcgaaacca
      301 tttaaatacc cacaagaaat gaagcgagca tggcgtaaaa tgttagatga tgagttgatt
      361 ccacttgaaa atgaattgag gtaaatgaga agagttaaga aaattgtacg attcaaagat
      421 agtagtaaag tggaagtgta gaaaataggg atagatgtct tttatttgtt cacattttat
      481 aacgaagtat ttaagacagc tattgaataa tgtttcctcc acctttttca ttcatttacc
      541 ccaccccgtt gttatatgac cgtgtttcga gaggaaccaa taaaaagcat aggctaacta
      601 ggggttcctt tttcttttga ttttttggaa tccgcttaag tgaaatgtat ctgaaatgaa
      661 acagagataa agtgattttt tgctgtaatg acaaggtttt agctgtttca gataccatgt
      721 aacccaaaat agtttattga gaaaatagga gagtatttga tactaactag taggaaaaaa
      781 tgagataaaa agtaaatgga atcatttcag gtaatctcaa ataaaaaata tacaggcctg
      841 tggcacttta cctacgggac tgtatatttt ttactctcag cgggcttgtt ttgactccgt
      901 gtttgactcc gtcgtattga ttttaaatga tattcgatga ccaattaata ggtcgttttt
      961 gaaatttttg tctctatatg actcagtttg ataattattg atagatcgat ttgggtctat
     1021 atcgaacaag ggaagattgc aaaagtcgaa gcttaaagga ttgatattaa aggattaaga
     1081 ggtaaaaagg tatccccata atatcctctg actccgtttt tgacctcgct tatcatccgt
     1141 tcatgtaaga atcaaataat tcgactgttt cattttgccg attttttgat actttaatat
     1201 aaatgtccat gattgtttta gaagaagaat gtcctagcct atcttgtaca tcttttactt
     1261 gagcacctgc ttcaaagaga agggtagcat gagtctttct gaagccatgg actttgatta
     1321 tcttcatatc tgggaacttc cgtgctactt tatccatgac atggttaggg tagcctttgt
     1381 aaaggaagtc ccttttttta ttccctttga tagtgctgat tacaggtata tcatctatat
     1441 tatctatccg aatccctcta gaaaggttct tttatgttac agaacgtttc cattttttag
     1501 aatacgtaag gttccattat caattgaaat tactcccttt gatttgtctg tttttgtagg
     1561 attaatacat agagagccct cggatagttc tactaacgtt ttgttgaagc agatagtttg
     1621 attatcgaaa tctatgtctc tacatgtcag tccgagtatt tctccttttc gttcccctgt
     1681 ataagaagct attctaaaga atactaaagc acgctcatct tttaacttat gcaaacattc
     1741 aaaaaacaga tatttcacat atatctaaaa ttcggagatt gaaagaatga atttatctaa
     1801 gaattttcac taatgttgcg aatataatat cagaaaattt cgaaataaat tttgttaaaa
     1861 attagaaaaa tccgaatact tagtagtgga taaatttttt tcaggaatag tacgttttat
     1921 taaaatgaaa actaatccga catcaacttt tttatcgaag caaacatcaa gcggtaaaaa
     1981 gacctcttta gtttgaaaag tgttgctttc atattgattt aaattttggt taagtaggta
     2041 aattaagaaa tgatcagtgt aagtatttcc tgatttagcg caccttgttc actttgaaaa
     2101 tacaggtttt tgatggacag attttgcttc aaatgtttaa agaacatgcc actgtacttg
     2161 gtacaggtcg gcgcccccat ttggagttgc gtcagatcga gtcgtgacga ttcattttgt
     2221 acaaattaga atttaaaatt gaatacatga cgcgcacatt ttcccagaga gccatattct
     2281 gtaattaatc acagcaatta gtgattatgc acaatctaaa aaactgattt ataataaaaa
     2341 tattattcaa ataaataata ataactgccc gcatgatgtt gacagttaca atagcacata
     2401 gatagactgg caaagatggt tcttaatctt tcactttggt cagaattctt gggttatcct
     2461 tccagtgaaa gtcagcagaa aatccttaat gcttacaaat aatttttgcg aaataggttt
     2521 tattggtaaa ggactcaatc atgaatatga attactttta tctggtaaat ttggaaaaat
     2581 tttgcaaaga aataaaaatt agacaaattt gctacacata atcaaagatt aaaaaagttt
     2641 ttaaaatata gttgtttgaa tggggatatg aattagagaa aattggttga ttcaacgggt
     2701 gctatcattt ttgatagcgt catatgtgaa gtaagcacac ctaatgaaaa aggttcaggc
     2761 ttgctttgaa gacttattaa caactatgtc gactatcctt gacttagggt agaggagtac
     2821 ctccacacac cttaattaga tgataatgtt tggactgtag gctacttagc ggattaagat
     2881 aaagaggaag tagaaaaaga gccttgcgga aagacacttt atctgttatc cgcgaggctc
     2941 tttatacatt taagcatatt taaaaattat ttggaaacag tactttcaaa ctttgtctta
     3001 taagcagggt acttagatat ttcatattca aacggtttct gatttttagc aaatccaata
     3061 cttgtaaaga caaagactgg ctcatttttt tctaaatcaa gataaaggtt ttctaaatct
     3121 gttggcggtg taacttcaat tgagcgtttg gcataagcta atctaattcc cctactttct
     3181 aatactgaga acagggattc tttggcaaaa tcatgttcaa caatttcagg taaaacagat
     3241 aggggaatgc aactttttgc aatacaagtt ggatagtcat cgatgtatcg aattctttcc
     3301 aagacaagca ctaaagtatt ctgctcaatc tccaaacatt cactaattgt tgaatcagca
     3361 ggtatgatgg tttgttggat aatcttagaa ctgattttct ttccttgctg aaccgcatct
     3421 tggaagaatc cgataaaaga gtcgagttcg tggtcaacat atttttctga agctggtttc
     3481 actagatacc cgcgaccttc atttttagaa ataattcctt cgtcttctaa agaagctaaa
     3541 gctttccgaa ttgttggacg actcaccgaa aattcctggg ccaaatctct ttccgaaggc
     3601 aataattcag atttccgatc agtggtgata tacacttttc gaatttgttc ttttactttg
     3661 tcaaaaatca tagtaatcca tccttttacc aaggtattaa cattatatta ccattttttt
     3721 gacttaatat cccagatttt ccttcaatta attccttcgc cgctaattga ccccacaaat
     3781 agccaatata tcggtcataa aaagttggag atgatccacg ctgaagatac gcaagattta
     3841 agtatttggt ttcttttggt aaatttttgg taataaattc aatgattttt tgtttgttag
     3901 atataccttc tggtaaaagc aatataggcg agtagaactc cgactcaaat tttttacata
     3961 ttaagtgtaa gtattccttg tcgtctctct caacccaata agtattattt gcaatggaag
     4021 cgtactctgg aagagcaaag cagcctcggc ccatgacttc cattataata atacgatcat
     4081 gagcattagc agtagaagtt aaatcatcga ttgatcggat tatagtgttt aaggcgctat
     4141 cgaagccaag tgtataatcg gtattgggga aatcgttatc aatagtccct gggatgacag
     4201 atacttgtaa ttctgattca tttttcaata gttcagctcc tttcaaggaa ccgttacctc
     4261 caataacaat taagttgtcg atctccatct tatttaggtt ttcaataata attttccgac
     4321 tttcgagatc tctcattttc tcaaatctgg ctgttccaat aagtgttcca gctttgaata
     4381 cctcaacttc ttttagagaa actgaggcaa tacattcctt aaatattccg gcataaccat
     4441 tcttaaaaaa gactacttcc gaatctggtt cgctatcaat tgtttttttt attgctaata
     4501 aagctgaatt cattccggga gagtcgccac cactacagat aactgcgatt ttcattttag
     4561 atcctcctaa aaaaggtgac tgcgattcta ttctcccatt agagaaaatg aagcaatcaa
     4621 atgggcaatg gagtcgcggt cacctttttc atatttttat gattagtatt ccatttgctt
     4681 ataataacgg cgagtagtta aagggtggtt acgttcttct tctagaaaag cactaattcg
     4741 ttcaaagaca gtagctaaga cgactgggga aataattttt cgcgtgtctt ccgaaatgcc
     4801 aggtaagtca tagtcctttg tatcaaccgt tacgtgaaca tctgtaaact taggaacgaa
     4861 attcttcacg cgttctgtga gaggtcgaga atcatcttct ccttctgtaa tgatgacact
     4921 tacacccgct tcaattaatt caagagttcc atggaagaag tctgctgcat gaacaggacg
     4981 agtcttaatc cattgcatct cttctaaaat acacatgcca tagtaatatg cttccgcaaa
     5041 gctatcacca gcaccggtta aaatatgata tgaagtatct ttgtgttttt ttgcaaaaga
     5101 ttttgccatt ggttccgctt gctctttagc gtgcactaag gcttcaggta ttttttttaa
     5161 atcctcaata taggtattgt attgattgat atcgatttca tttctttgtt tcattaagaa
     5221 gagagcaatc agcagtcctt gaaggtaata attttctgaa gatgtatcat ctaaaacgtc
     5281 gttatagata gaatatgttg cagctttttc taggggcgtt ttaggacttc ctaccaaagc
     5341 taatgttttg acgttcattt cattacagta ttcgactaac tcaagtgttt cttttgttgt
     5401 accagataaa gatgggataa caaccaaaga tttgttagaa aatgttttat tgggatgaat
     5461 cataaattcg gcagcgataa cacgatgaaa agggaaagtg ctacgagttc tcgcgaattc
     5521 gattgttgaa tcaaaaagaa taccaactcc tccagaccca ataaagtaaa tttcttctaa
     5581 gtcagatgcg atggattcta aaatattgga aatttgttca tttgttgcaa cggcaccagc
     5641 ttgagtcttt aaaaatcttt cttgatcaaa attaaacata aaaatctctc ctttgattac
     5701 caatggtaat attttgtttg cataaataaa ataccacagg taataaaaag tgtcaaatat
     5761 tttttaggaa aaataccata ggtattgtta aagtggaaag atgtttataa agaatattga
     5821 attttatagt gaaaatcatt tattattaag taaaggaggt gggttcattt gaaaacgaaa
     5881 attttaaaag aattaaatga tctacttaac agctatgatt ttccacaata ttttccagaa
     5941 gaatgtaacg cgcaatatat tgcccaaaaa tttcaaataa aaagaaatac ggctagtaag
     6001 catctaaacg aactaatgga acagaaaaaa gttgtgaaaa tcaatggtcg tcctgttctt
     6061 ttttttccag tccatacaat tgaacggtat atatcacatt cattagatag ttttgagttt
     6121 tcttcaattg attcgtttag agaaaaaatt tcaaagaaaa aagcagatca tttttttgat
     6181 gatttaattg gtgcaaaaca aagtttaaaa gaagcggttc aacaagggat atcagcaatg
     6241 aaatatccag gtggattacc aataatgtat tttggatcgt ccggagttgg gaagagttac
     6301 ttagtggaaa aactagctga gtattgccga caaactggta ttattcatga gaatgctccg
     6361 ttcatcgagt taaactgcgc tcagtatttt aataatccag agttattaac aagtcagttg
     6421 tttggccata tgaagggatc gtttaccggc gccgattctg accatattgg tataatagaa
     6481 gcagcagacg gtggaatcgt ctttcttgac gaaattcatc gtttaccacc agaaggacaa
     6541 gagaaacttt ttattcatat ggataaaggc gtttttcgaa gagttggaga tagtggtcct
     6601 tggcgtttat cacatgttag atatattttt gcgacaacgg aacaggaaga aaattttttt
     6661 ctagaaactt ttcgacgaag aattccgatt gtttgtactt tgcctaatta ccaagataga
     6721 gaaattagcg aacgaaaaga gattgtcttc catttattag agaaagagtc tactctgatc
     6781 aataaagaaa tattagtttc tgaagccgcc cttagtttcc tgattcgctt agatttgtat
     6841 ggaaacattg gtgagctgga tggactaata aaacaaacta ttgcgaataa actatttagt
     6901 ggaagcaata aaaaatatat cgaaattcat atttctgatt tacctagcag gtacttgcta
     6961 acagaaaata ttgagttaaa aaaccaaatt gcgagccaac ggttctatat ctttagtaat
     7021 ggtaactatg ttcatgattg tgacgagact tcaactgtaa ctacaaattt acgaggtttg
     7081 attcatcgtg tttctaaata ttattcagag tgtcatgatg tgaatagaaa tagtgaagag
     7141 tttcgacgtt ttgtgaagga ccaaatggca gaatttaatg atcgttttat ttaccaaaaa
     7201 aattcagaag tcttagttaa gtattattta ccggaaatcc aaaatattgt tcaaaaaatc
     7261 tctcccagtc tttttgttca cctttctggc aatacggtcc aagctatagc tacctatctc
     7321 gctattaggg atcaatgggg gtatgggaaa gagaatgctt cagcgaatga aattgaaaag
     7381 ttatatgaaa acctaaagtg taactatttg acggatttaa atgtattctt actgatcttc
     7441 gagaacgccc tggatacaac attgactatt tgggataaac tgtatatcag tttgtgtgtt
     7501 attagtgaga ccggaaatga agcgaaagac attaacgcaa ttattttagc ccatggatat
     7561 gcgacagcta gtagtattgc taatgttgcc aatcgtttgg ttaatcagtt tgtcatagat
     7621 tctattgata tgcctctaga tatcagcttt agtgaagtaa ttgacagatt acttcactat
     7681 atagagtatc gaaagtctaa aaatggacta gtgattttcg ttgatatggg aagtttagct
     7741 caaattaaga ctgaaattga acaagtaatc gaagttccaa caatgattat taataatgtt
     7801 acaaccgaaa tggctattga aaccgcacaa ctgattcaaa gtacgagtga tatccaaaag
     7861 gttgtaaaaa aattgccgta ttctcagttt gaaaagcaag ttctatatcc catcaaaatt
     7921 agaaaacgta caatcgttgt ttcctgcaat actggtttgg gtacctccat aaaaattaaa
     7981 gaaatgatgg aaaataattt gtcgaaagac ttgggcattg aatttctgcc atacgaaaat
     8041 gaaactctta gagatactca gcaattagag tttctcatta aaacaaagga tatcattgcc
     8101 attatcggaa cagatgatcc gcgtgtgtcg aacattccct atatttctct tgaagaatta
     8161 tttgatggtg aaattggcaa actctataaa gttcttttga gagtctatgg aaaagagatt
     8221 gctgaggcaa ttaatcaaaa tattgttaaa aatagctcat taaaccgctt gattgacagt
     8281 cttactattt tagatgccga aaaagttgtc aatcaaattg aggaaagttt aaaagattat
     8341 caaatgaggg tggggaaaac gttatcatca ttgtccaaaa ttaatcttta tgttcatatc
     8401 agctgtatga ttgagcgact aattcgtaat cagggagtaa gtagttatcc agcaatagat
     8461 cagtttctta agcgatacga aactgaggtt gcttctattc aaaaggcact tagtaagatt
     8521 gagaaacttt ataatattaa gattcctatg gaagagattg catatgtgtg caacatcatt
     8581 gtaagttatt gataaaataa agtgacacta ttcacagcga tggaaatagt gtcactttat
     8641 tttttgtacg ccctttcatt taagtggtga cagtaattgg cacagtattt gctaataaca
     8701 aagcgaaagg agttcgggta tgagacaaat attatgtatg agccacggtc ctctagcaaa
     8761 aggaatgatt gaaactttga gtattatcgt aggagatttg gataatattg attttcgatg
     8821 tgcctatgtc gatggaaata atgacgtaga aatgatcatc gatgattatc taaaggaatc
     8881 tatgggaaat gagacgattg ttgtaaccga catttttggt ggaagcatta ataatgagtg
     8941 gctaagacgg ttgccagatc tttctaaagt ctatttgatt tctggaatga atttaagtct
     9001 tttagtggat ttatatttaa aattccaatt agtttcatct gatcagattg aagaaattat
     9061 tgatcatgca attcaagcat cttctggttc gattaagttt tgtaatcagc tagattatga
     9121 gcaaacggtt gatgactttt aaataaagga gggaagagaa tgattaaatt agtgaggatc
     9181 gatcatcgtt tgatacacgg tcaagttgct ttaacttgga cgaacgcaat cagtgcggat
     9241 tgcattttag tagcgaacga tgaaattttg aatgatccaa ttcaaaagac aactttgaaa
     9301 ttagccgcac cacataacgt gaaggttgtt atcaaatcaa ttcaagattc gattgatgca
     9361 attaatagtg ggaagacaga taaatacaaa ctatttgtag ttaccaaaac catttccgat
     9421 gctaaacggt tggcaaatgg ggttgaacaa attaaatctg taaatatcgg tagtgttaag
     9481 gaaactagtg gcagtagcgc tttgacgcat acaatttttg taacagaaga ggaacgagca
     9541 gaacttaaag gaatggtctc agagggcatt gaagtgttcg ctcaacaagt tccaacagat
     9601 aaggcaatag atttaaaaaa atctttgtaa taaaaaaata agggggtaat ttcatggata
     9661 gtctcttagt acaagcaatt ttgcttggtc tcttgactgc gttcatcgta attgactgga
     9721 tgacaggtac gaataactta tcaagaccaa tcgtatcttc cgtctttgtt ggtttaatta
     9781 tgggcgatct taagatgggg attatgatgg gggcaacact ggagttagca tttatcggag
     9841 caataacaat cggagcggca cgtccgcctg atacggtatc tggtgggatt ttagggactg
     9901 cgtttgctat tgcaactggc aagggagcag aatttgcgtt gaccttggca ttcccaatcg
     9961 ctgcgctatt cttattagtt gataatctac taacattgct tgttctacca atgattgcta
    10021 gaaaggcaga tagatatgct gaaaagggcg aactaaaaaa tgtgtcgaaa atgcatgttt
    10081 taggttttat cttagtaaaa agtttaccac gggctttatt tgtcggattc tcattttact
    10141 taggaagtcc tgttatggaa cgaatcttaa atgctattcc aacttttgtc caagatggga
    10201 ttaacattgc tgcaggcatt atgccagcac taggttttgc tattttattg caaatgcttc
    10261 ttaagaaaga tgtctttgta tatttcgtaa ttggttttgc actctttagc tacttacatg
    10321 tgccgattct ggggattgca atcttcggcg catgtctagc ttatattata gtaaacatgg
    10381 aaaccaaagc tgcaatgggt tcaagagggg aggagatggt tgaagatgac ttctagtggg
    10441 aaagctttaa ctaaagatga tttaacaaaa atttgtattc ggtcatgtgc attagaagca
    10501 tcatggaatt ttgagcgcca acaacatatg ggctttgctt ttgctatgat gccagcgtta
    10561 gaaaaaattt atagtggcaa tgaagaagaa aagcaaaaag cagctcaaag acatctagag
    10621 ttttttaaca cagctccgcc attatcaaca ttcataatgg gaattgtggc ttctatggaa
    10681 gaagaaaatg ccaaaaatcc tgatgacttt gatacttcta caatcacttc tattaaaact
    10741 gcattgatgg gaccattagc tggtattggt gattcaatgt tttggggtac cttattagtt
    10801 atcggtatcg gtgtaggtgc ttcattagca aaagaaggca atattttggg tccattttta
    10861 tttttactaa tcttcaatgt ccctaatttt cttctccgtt actttggagt tatgcaggga
    10921 tataactttg gtacaaagct attagagaac attgaatcct ctggcgtcat gaaaacgttg
    10981 actcatgctg cctcaatttt gggtcttatg gtaattgggg gcatgtctgg aagtatggta
    11041 tcaatcaaag tagctggttc tattggacaa ggtgatgaag caacaaaaat tcaaagtatc
    11101 attgatggta ttttaccaaa tctgctgtca gtattatgtg tatttctgat ttactggatg
    11161 cttaaaaaag gctttaaaac aacttacgtg ttattcggaa tctttatctt tggtatcata
    11221 gcagccttct tcggattttt gacaacttaa ttgaataatc taaataattg taaggagaga
    11281 actaatgtta aactataatg caaaagaaat gaaaaaaaaa ggcaaacgga tttacggtat
    11341 tcgtgaagat gtagaaaaaa ttgcaaagca agcttatgat tctggaatta gtaatatttt
    11401 ctttactgct tctggtggat cggtagccgt aatgcaacca tttgagtatg tattgatgac
    11461 tgaatcaagt attcctgttt actctatgac tgcagctgag cttgtcttaa tgggacataa
    11521 acagttgaat gaaaaatctt tagtaatctt atactcaaaa tctggagata cgaaagaaac
    11581 tattaaggca gctgaatatt taaaagaacg aaacgtgcca accgttggta ttgtaagtaa
    11641 agaagataca ccgttagagg ctctatcaac ttatgcaatc aattacctag acggccgccc
    11701 tcaagaaatg ccactttatt tcttaattat gtctatcatg aatttgaatg gggaatttcc
    11761 tgaatacact cgttttgctg atgaactgaa aaacttacca acggctctga attcagttag
    11821 agaacaggct gatgaaaaag ggaagaagta tgccgaagaa tttaaagaag atccttatca
    11881 aatttggatt ggtagcggga atttatgggg aatcacctac tcttattcaa tgtgtgtgct
    11941 tgaggaatct caatggttgc gtacaaagtc tgtctcatca ccagagtttt tccatggtac
    12001 cctcgagtta gtcgaaaaag gagtttgtgt aacacttttg aaaactgagg gggaaacacg
    12061 gcttttagat gctcgagttg aaaaatttgc ggtccaatat acagataaat ttaatgtttt
    12121 tgatactaag gattatgagc taccaggtat tagtgacgaa tttcgaaagt acttttgtgc
    12181 tccagttatg tgggcagccc taggtcgcgt cagtgttcat cttgaagata ttcggaacca
    12241 ctctttggat aaacgtcgtt attaccgagt agttgaatac taaaagtagg tgattaatta
    12301 tgacagcgta tgtgattgga tttggcgata atgttgttga ttactatgag aatttgaatc
    12361 aaaaatttcc agggggaaat gcagttaatt ttgctgtgaa tgcaaaaaag agtggtgtta
    12421 aagcatacta tgtcggtagt ctatcatctg atcctgatgg cgtgttatta caacacgcca
    12481 tcagttctga aggtgttgat atctctttct cggaagttat tgacgagcct actgagcaag
    12541 cacatgtaac tattaaagat ggagataggg agtttatagg tggcgtgcgt ggctcccgat
    12601 tgacacctgc tctctcagca gaacttattg atttgatgaa gaacagttca ttagttcata
    12661 ctagttgcca tagtcgaaca gaaacaaaaa ttaaagaatt aaaaaaatat gatgttaaag
    12721 tttcttttga tttttctgac ttagataaat atagaacgca tgaatacttg tcagatgttt
    12781 gtccgtcaat ttatattgca cagttttcag tcgctacaga tgatcaagag gaaattaatc
    12841 gcttaattag tgaatgcaag gactttgagg ttccgtatct tctttttacg cgtggtagta
    12901 agagccctgt ttttgttgac actcgagaga ataagactta tgaaggattc attcgcaaag
    12961 ttgagtcacc tcatgataca atgggcgcag gtgatgcata ctttgcagct tttgcaagta
    13021 attttgtctt atctaaacgt gaaaaatcaa tgatagaaca tgttattgat tgttttcaca
    13081 aaggtgcaaa ccttgcatat gaaacattga tgattgatgg ctcctttggt catgctacac
    13141 ctattaaccc ttagctttgt gctttgggct tttattgctg gaatttgtat agtagactca
    13201 tcataactat atttttgtat gtgaaaaggc aagaggctat gatgaaaata acactggcta
    13261 attgcatgag ggagcatatc gttgttaaag cgtcattgat agtatgaata aatatctcga
    13321 taatattata ttgttattta cttaatttat tgattagtca agcaaagata atcttctgtt
    13381 acttaacgag actagtaggt acaagcactt catgttatgt acgacccaaa aatattgctg
    13441 ttgattattt gctgaaatta ttgcgagctt caatttattt ttaaaggact tggtaggctg
    13501 cgtgatgaaa taagacttgg aaggctgtct aaaccaatat atagtagact aaatagtaaa
    13561 aaagagcatg gtaattgtct ctttgtcaat aagtctaatg gtaataagac aagttggaga
    13621 ttgagaatat ttttattgtg taacctattt tgaagcgtac ttaactagcc ccggccaaaa
    13681 tcaaattttt tcggggtata tcaagggttt gcgtcaataa cagaatgtta tttatctatc
    13741 acgttccttg gtggcgtgta gagttgatgg ttacgtagta gcgtatctac cagacgcgta
    13801 aattttcttg cggttaagac gtgtgctcgt ttgtgtttat ttttgggacc tctttacatt
    13861 tgctttgata aaaagcttta tattgaggaa gatatttttt tacagagttg gaagcttcaa
    13921 ctaagtagta tctaaaatag cgactccttt gttttgtcag aggtgtattt tgtgaccgat
    13981 agttaacaga ttgtttgcct ttccaacata agcctgcgta ttttgccaat tttgtttgat
    14041 cttcaaatcg ttcaatttga ccgatttcag cgattaatcc agcggcgtgt acctttccaa
    14101 tacctggaac actagtcaaa tattgatatt ctggaataac gacaacaaat tgctcggttg
    14161 ctttatccaa gtctttgatg ttcttttcaa gcgcacgaat ttcacataca aaaacattta
    14221 gaacgacatt gatggattct tatgcaagac tatctaaccg ataactcacg gcaattgcac
    14281 gttgaatcga tttggcattt ttttctggat ctttaaagcg acatttcctt tttcttttag
    14341 taagtcacag aaagcttcca aaggaagcac agccaattca tctagcgtga agtcttctgt
    14401 cacaagagta atgacagtgg cactatagag acttgtcgat tcatcgcgca tttatcgagt
    14461 aagcgtattg catttgtacg ttagattttc cagaaagtgt tgttttgtac gagtgaagtt
    14521 gcttaatgag tcgatagcga gtgcgtgtta aacgctgtaa agccacgtac ttctcttctt
    14581 tgataggaga agttgtgaac cgttgaatac gcaataaatc agcaattctt aacgcgttgt
    14641 ttcgatcagt cgtatcttcc tcaaacatgc gactgaattg tttcatccga aaaggatttt
    14701 caatcctcac aagtgcattg agttttttta gctctgcatc ttcatggaaa aac
//
LOCUS       DAPBCF010000059        14212 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.060, whole genome shotgun sequence.
ACCESSION   DAPBCF010000059 DAPBCF010000000
VERSION     DAPBCF010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.060"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(163..2160)
                     /gene="tkt"
                     /locus_tag="RD508_002307"
     CDS             complement(163..2160)
                     /gene="tkt"
                     /locus_tag="RD508_002307"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDT7736845.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2262..2513)
                     /locus_tag="RD508_002308"
     CDS             complement(2262..2513)
                     /locus_tag="RD508_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HDT7736846.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2660..3283
                     /gene="lexA"
                     /locus_tag="RD508_002309"
     CDS             2660..3283
                     /gene="lexA"
                     /locus_tag="RD508_002309"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HDT7736847.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3463..3681
                     /locus_tag="RD508_002310"
     CDS             3463..3681
                     /locus_tag="RD508_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736848.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3970..4482)
                     /locus_tag="RD508_002311"
     CDS             complement(3970..4482)
                     /locus_tag="RD508_002311"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDT7736849.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="RD508_002312"
     CDS             complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="RD508_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDT7736850.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6935..7378)
                     /locus_tag="RD508_002313"
     CDS             complement(6935..7378)
                     /locus_tag="RD508_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HDT7736851.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7379..8167)
                     /locus_tag="RD508_002314"
     CDS             complement(7379..8167)
                     /locus_tag="RD508_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7736852.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8164..9105)
                     /locus_tag="RD508_002315"
     CDS             complement(8164..9105)
                     /locus_tag="RD508_002315"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HDT7736853.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9282..9869)
                     /locus_tag="RD508_002316"
     CDS             complement(9282..9869)
                     /locus_tag="RD508_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HDT7736854.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10090..11397)
                     /gene="obgE"
                     /locus_tag="RD508_002317"
     CDS             complement(10090..11397)
                     /gene="obgE"
                     /locus_tag="RD508_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HDT7736855.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11700..12710
                     /gene="gap"
                     /locus_tag="RD508_002318"
     CDS             11700..12710
                     /gene="gap"
                     /locus_tag="RD508_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDT7736856.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12795..13730)
                     /locus_tag="RD508_002319"
     CDS             complement(12795..13730)
                     /locus_tag="RD508_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7736857.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13916..>14212
                     /locus_tag="RD508_002320"
     CDS             13916..>14212
                     /locus_tag="RD508_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7736858.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKER"
BASE COUNT         3968 a         3160 c         2510 g         4574 t
ORIGIN      
        1 tctcaagaaa cacaaactaa tccgaagaat tctttgtttt gtcatttaaa tgtaacatag
       61 ccgaaaacga aaagtaatat tgatttattc ttctaacaca taaagaacag ctgtctccaa
      121 cttgcagaca gctgttctta tcagtcaaac aattgcttgg atctatgata gttgattgta
      181 cgtattcacg acattttcta ctgtaaatcc aaattcttct aaaattttag tgccaggggc
      241 agatgcaccg aaatgatcga ttgtaatcgt tgcgccctct gttcctacgt agcgttccca
      301 tccaaatgat gcagcagctt cgatagccac acgtttcttc actgatttag gaagtacact
      361 ttctttatat tcagaagatt gtttttcaaa gaggtcaaag cttggcatag aaacaacaga
      421 aacatctttg cctttttcag ccaattcttt ttgagctttc acagccaaat caacttcaga
      481 acctgttgca atcaaaatac cttctggtgt ttctccttgt gatggagaaa gaacatacgc
      541 gccttttttc accatttcat ctgctacttc ttttgtagaa ggcaatactg gaaggttttg
      601 acgactcaat acaaggatag taggcgcatc tgttgtctcc atcgctactt tccaagcagc
      661 acgtgtttca tttccgtctg ccggacgaat cacttgaaca ccaggcatgc agcgaacaga
      721 tgctagttgt tcaatcggtt cgtgcgttgg tccgtcttct ccgacagcaa ccgagtcatg
      781 tgttaagacg taaacaacag gagtatgttg gattgctgct aaacgaactg ctggtcttag
      841 ataatcgaca aagacaaaga atgttccacc gtagatacga gttccgccat gaagttggat
      901 accattcata gccgaagcca ttgcaaattc gcggacaccg aaccagatgt tgcgtccttc
      961 ataatgttca ggagtgaaat ctttatctgc agccaccatt gtattattgg aacctgacaa
     1021 gtccgctgaa ccaccccaga agcttggtat agctttcgat aattcttgga tgacttcttt
     1081 acttgaaaca cggcttgctt gactgcttcc aacttcataa gttggcaatt ctgcatccca
     1141 gttttctggt agtttgccat caaaagcatc ttcaaattgt tgtgctaatt caggataagc
     1201 ttttttataa ttggcaaaca tttcattcca tgcatcttca gctttttgtc cttcttctat
     1261 catcgtttga tggaagcggg cagctacttc ttctggaaca gtgaaatctg gatactccca
     1321 accataaact tctttagcca tcttgatgcc atcttcacca agaggagcac catgaacagc
     1381 agatgttcct tctttaggag caccatagcc gatgactgtt tttacttcga tcaatgttgg
     1441 tttgtctgtt tcagcttttg cttcttcaat cgctttagag attgcttcta ggtcatttcc
     1501 gtctttcact aagatatgtt gccagccata tgcttcatag cgagcaccaa cgttttctgt
     1561 gaaagctttt gaagttggac cgtctagtga aatatcgttt gaatcgtata aaacgatcaa
     1621 tttccctagt ttcatatgac ctgccatcga acttgcttct tgagataccc cttccatcaa
     1681 gtctccgtca ccgcatattg catacgtata gtgatccatc acattaaagt tttctttgtt
     1741 atacgttgct gcaaggtgcg cttctgccat tgccataccg acagccattg caatcccttg
     1801 tcctaatggc cctgtagtgg cttctacacc atctgtatga tgtacttcag gatgtcctgg
     1861 tgttttagaa tcccattgac ggaattgttt caaatcatcg attgtcactt gatagccagc
     1921 taaatgaagc aagctataca acattgctga cccatgtcct gccgaaagaa cgaaacggtc
     1981 gcggtcagcc cagttttttg atgtcgttgg atttactttc aggtgttttg tccataacgc
     2041 atatgccata ggtgctgcgc ccatcggcaa tccaggatgt cctgagtttg ctttttggac
     2101 tgcttcaata cttaatgtac gaattgtgtt aacgccaagt tggtcaattt tgtcaaacaa
     2161 aataacccct cctattaatt taggtttttt ttacctttat ttcttacact ttcattctat
     2221 aagatgtcac acgaaaaagc aatctttttc agtatttttt actaaaagtt gtcatttcgg
     2281 ttgtgtaagc cttttttctt ttggatttct tttaattttt ccggggtcac gtcattgccc
     2341 tcaggatcga cgactttcat tccttcgata tgatgacgca taccggaacg aaaagcttcc
     2401 aaatactctt tgcgcaagtt gatttgttct tgttcttcgg cttttgagag accattttcc
     2461 ttctttttac gtgcaagttc attgatccgc tctatttttt caggtgacag catgctcagc
     2521 cctcctttta ctctccttca tattatataa aaactgaaaa aaaaacaact agataaacta
     2581 aataaaatac gaacattcgt ttgatttagc gctttttata tggtactatt tatttatcaa
     2641 gtgaaagaag gtgtaccttg tggcccgaca aactgaatca agacaaatcg aagtcttacg
     2701 atatatccat gaacaagtaa cccaaaaagg atacccgccg actgtccgtg aaatcgggga
     2761 agctgttcag ctttcttcta cttctactgt tcacggtcat cttgcacggc ttgaaaaaaa
     2821 agggtttatc caaagagatc cgacgaaacc tcgtgcaatc gagttgacaa aacaaggttt
     2881 agaaaagatt gggattcgtc caacaactat tccagtactt ggcgtcgtaa cagctggaga
     2941 acccatttta gcagtagagg atgcttcaga cttctttcca atccctccta atctttcttc
     3001 cgaagaaggc agtctcttta tgctgacaat tcgtggagat agtatgatca atgctgggat
     3061 attggatggt gacaacgtga tcgttcggaa gcaagaaact gctcaaaatg gcgatattgt
     3121 cattgcaatg actgccgagg acgaagcgac ttgcaaacga ttctataaag aaaaaaactt
     3181 tttccgtctg cagcctgaaa acgacttgct cgaaccaatc atcttagatc aagtatctat
     3241 attaggacga gtagtaggac tttatcgtag tcatatctat taattgctac taattaaaag
     3301 aaaacttttt aaaaagagtt tgagacgttg gtctcaaact cttttttcgc ccgggttctt
     3361 cttctttcaa atttttatca cttccctctt tacaaaccga acaaatattc gtatactaaa
     3421 tatacgaaca attgttcgca taaattaaag aggtgagaat tcatgaaatc aatgagacgt
     3481 cttggcttag tattaactgt tttgttttta ggtattatta ttggtaattt cggcatacgt
     3541 ccagctttac ttgtgtttgt tccgttattt actttgtggt tcatgttgtg ggatgaaaag
     3601 aagtaccgtc aatctgagcg gcgcagaatt catgaagatc atttctatca tgagccctac
     3661 tacagatcca ggcaatcata ataaggattg actgctaatt attcaaaaga caagaagtta
     3721 aacttttacg ggggtgtgac aaaaatcggt cacatccttt ttttcgaata aacggtgttc
     3781 taaagccagt ttttcggtat taagtcaaat tgcggaaaaa gtgatttttt aaacttctac
     3841 tggtctttgc ttgtttccat ttataaaaaa atagcgaccc tcaaaagtca gatagagaat
     3901 ctgacttttg agggtcgctt taaaatcgct tctttaagaa taacatcaag aatagcttct
     3961 tttttctgct taatattcca ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc
     4021 atggagatcc atcaattcga tcaaaaatgc gcagcctacg actacaccgc ctaattgttc
     4081 gatcagttcg atcgtcgctt tgattgttcc tccagtagct agcaaatcgt cacaaatcag
     4141 cacacgttga cctggtttaa tggcatcctt atgcaatgtc aatgtatctg ttccatattc
     4201 taatccataa gtcacttcga tggtttctcg aggtaacttc ccttttttgc ggactggggc
     4261 aaaaccgact cctaactcat aagcaacagg acatcctacg atgaatccac gggcttctgg
     4321 cccaactacc atatcaattc gtttttcttt tgcataattt acgatttgtt tagtagcttc
     4381 ccgataagcg tcaccatctg ccatcagtgg ggaaatatct cgaaacacaa ttccttttga
     4441 cggatagtcg ggaatactgg caatataatc ttttaaatcc actctttgtt tcctcctagg
     4501 ttgttaacca tttctttatg gtaggaatat cgctcaaaag caaaaattcc tcaactttga
     4561 ttttattgag ccgtcgctgg tataatctgc tctcagtcaa aggatgactt tctgggctag
     4621 cgactttttg taaaacaccg ttctctattg taacaaattt caattcaaaa aacacctgta
     4681 tcataaaaat taataatttt tcagggatac gcaaatattg agctattgct tttattttat
     4741 gacgtatatc aattcgttct tgagaatgga tcaatttaaa caattttgcg tactgttctc
     4801 ttgtgcctac cccattcaaa taggcctcat caggtgaaat ccccatcaga taaacacgat
     4861 tgaatgaata agaccgaaaa acttctttca gatccgctaa atcatctgga caatccataa
     4921 caactagaga gtttggtttt cttttttcaa ttattgcctt tacagaatct agtccttcga
     4981 aaacaatcgc agcttcctgg ataatctcag gcacgaattt caacgtcgaa gaatcaaatg
     5041 ctaaataaag gctaccttcc gacgttcggc tctgttcacg gaaacgtttt gcccgccaat
     5101 caaatacttg cagaccaccc acagaaaaat cagataccat cagctgcggt ttcttacgcc
     5161 cgttccattc attgatcgaa agctttccta ccacatctac ctgattattc agcagttctt
     5221 cttcttgagt accaaaacca aaagcgaccg catcaagctg actcgatgca tcggaaagga
     5281 caaatttcag atgctgttgg tttgctccga ttcttttgat attttctgct tggacttgtc
     5341 gaaataaaaa ctgaggcaaa ggattatccg taccaaatgg cgccaatagt ttcagctcat
     5401 caattcgctc tactgttact tcatttggca gcaatacttc atcaattctc aactcaggcc
     5461 ctctcatcaa gtcaatttga tgatcgacta tatattggtt catcttctcc tgtagtatag
     5521 tgacattttc acttggcatc gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa
     5581 ataaatctcg catctggtca agcatttcaa aaagattcaa ggcttcaata ctacgtccag
     5641 atcctttagc tgatccatct tcttttaaag taaggacaag cgttggttta cccgtttcat
     5701 tcattatttt cccagcaaca atgcccaaaa cgccttcatg ccatcctcgg tttaccaata
     5761 gatggatatg attctcctta ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga
     5821 ttgcttttct ttcttcattg atctcattca atttttttgc ttgaacggat gcttcctctt
     5881 catcaaacgt cgcaagtaac gagacggcag gacgtggatc gcccatccga ccgattgcat
     5941 ttagtctggg agcaatcgaa aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc
     6001 cgctttcttc aaatagcgcc tgaagtccta tccgttctga atgatgaatg gcatcgattc
     6061 ctaatgaaac aaggattcga ttctcatcag tcaatgaaac taaatcggcg atcgttccta
     6121 tcgctactaa atccaaaaat tctgcaggcg gttcttccaa taatgcagaa gctactttga
     6181 atgctactcc gactcctgcc aaatctggaa atggatagtg ccccgctgga tgacgagggt
     6241 gaacaatcgc ataagcgtct ggtaaattct caggtagttc gtgatgatct gtaatgatca
     6301 cgtctacacc agcttgctga gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa
     6361 cagtgatgat caactggatt ccttcttcga tcttttcttg gtataccgat tggtttggtc
     6421 catacccatg ctcaaatcga tttggcagga atacttctac ttctgcacca agtaattcca
     6481 gtgtttcttt cattaccgtt gcactggtga tcccatctgc gtcataatca ccgtaaacga
     6541 ggattttttc tccactgatt acagcttctt ggattcggct gattgcttta tccatatcgt
     6601 gtatcagata cggatcatgt aattcttgtt cctttggatg taaaaatcgg ttgatatcct
     6661 tttcctcatg gtaacctctt tgccacagta acttaccgac aaatggagat aatttcagtt
     6721 cacggatcat ttggagaaag gattcagaag gctctgtctc gcttaacttc caatcaaaat
     6781 ttgcttgtct cactttctca ctcctaactt agttattata gcaaaggaaa tcagcaaaaa
     6841 aaagcagaaa gaaagaataa aaacagatca gatccgctag acagatgttc agcaggacct
     6901 gatcttttgt acgaccattt atgaaatatc cctattagtc aaaataattg aagctttgtt
     6961 tgggcgattg agttttttgt tcttccggcg ctttcaattg actgatttgt gcggttttcg
     7021 cttgtaactc cgcctgataa gcagcttcca actccgcacg ttcgtttcta aactcgcgtt
     7081 gctgttcttc ttttgcttct tcaattttct tttgaagttc tgtttgatat tctgacattt
     7141 cctgagtcag ctgtttgatt tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa
     7201 atacaatcag tgcaccaatc agcgcagaac cgatgatcac taagatcaat ggcgcagaaa
     7261 aggaagtgaa gccaaaactt acaggaacat ttttattgtt caatacagca aaaagaacaa
     7321 taatcaaaac taaaacaaat ccaagaatca cattgctttg ctttttcaat tccttcacct
     7381 actttttgtt aaaaattccg ctggctaaat aatcaccaat cgttggaaac agcgtataaa
     7441 attttgatgc aacttctaaa ataaacggtt gattgatttc ccgttttgga tgtctcatat
     7501 tgcggacgat catttttgcc aacttggcag gttctaaaac gatttgtccg actttttcca
     7561 aatagcttcc gcttggatca gccttatcga agaaatttgt ctcgattgga cctggattca
     7621 ctgtcgtaac agctacgcca agtggtttca attctaatcg caaagcgttg gagaagccaa
     7681 ggactgcaaa tttcgtggca gaataaaccg ttgattttgc agttgccatt tttccagcca
     7741 tagaggcgat attaatgata tgaccttgtc ttctttctgc catatcgatc gcaaattttt
     7801 gtgtcaaaac catcattcct aagatgttga cttcaaacat atcgtatgct tttccaaggt
     7861 cgaatgtaag gaagtcttcg aaaatcccaa aacccgcatt gtttaccaga atatcgacgc
     7921 gcccgacttc ttccatcacc ttttcatata attcgtccac gctttcagga ttgctgacgt
     7981 ctaccttgaa agcataagcc tctttgccgc tcaagcgtct gcactcgtct ctgacacctt
     8041 ctacaaatgc cattcttcgt gcgcaactta taacgattgc tccttgcttt gctgcttcat
     8101 aacagatttg tgcgcccaga ccgcctgaac tacctgttac taaaacaact ttatcttcta
     8161 aattcatgcc tcttcctcct cgcgaaatgg aatctcaatg ctatcaaaat ctttcataat
     8221 cgtcgtgttt tcaaacactt cttgtgcttc tttttcaagc tctaaagctg cttttcctaa
     8281 atatctcgca ctgatatgag taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc
     8341 agcagcttga tgagtcgtgg aatggaaata gttgtgcgcc attcttgctt catctttatt
     8401 aaatgtgctt tcatgtacca gaatatcgct attttccgca agcacaacgg aattatgtgt
     8461 ttttctcgta tcgcctaaaa tagtcacgat tcgtcctttt ttatctggac ctacgaaatc
     8521 ttttccattg atcgtccgcc catcttctag ttggatcgtt tcaccttgct tcagtttgcc
     8581 gtacagtggt ccagctggaa tacctaattc ttttagacga tccacctgca attctccttt
     8641 atgatcatgt tcaaccacac gataaccaaa actgtcgatc ccatgattta gtttttttgt
     8701 ataaacagaa aattgctgat cagtaaaaat cggggctgtt tcatttagct caatgaattt
     8761 cagcggataa cttaaacgcg tttgcgaaat acctaaagag acttttatgt attcctctat
     8821 cccttttggc ccgtaaatct ctaatggcgt atccccacct tgaaatgacc ggctgctgat
     8881 gagcccggga agtccaaaaa tatgatcgcc gtgtaaatgt gtaatgaaaa ttttaccgat
     8941 ttttctcgga cgaatagtcg ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa
     9001 caaccaaact tcattgcgct cgtctaaaag tttcaatgct atacttgtca catttctatg
     9061 ttttgcagga acacctgcac ctgttcctaa aaattgtaat tccataatct acctgacttt
     9121 ctttaagttc ctctttaatt ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa
     9181 tgggttcaaa ttaaaaataa cgttctaaag cgatagcgtt ttctttgaaa attactataa
     9241 aaacagcagc gaacccgttt gagatcctct gctgtttttt attaatttga agatccagaa
     9301 ctttcattgt cgttggaagt ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct
     9361 ttcgcatgat tttcagcttc tttcgcatca tgcacatctt tttcgacatc ttcataatcc
     9421 aagcgagtaa tttctccgcc taattccatc attaccaatt gattcagtgg gcgattgtcc
     9481 tcttcatcag caatcaagat cagtcctgta gctccttcac cgattttatt tcctacaaag
     9541 tcgaacacgg tctgggcatc ttttatttct ttggcatctt gtgtcgcacc gatcattcct
     9601 ccggcaaacc atcctaataa aatccctagc ggaccaccta atacaccaac caacattccg
     9661 attaatccac ccgtagaaga tttgttatta ccggtaaagt cgataaaatc ttctattttg
     9721 aattgatgtg tcccattagg atcatggctg acaactgcca tctgttctcc tttaatcgaa
     9781 cgaacagcat gtaacttttt gatttctgaa aatgcctgat atgcctggct ttctacttga
     9841 aaatttaaaa tgattactcg tttgctcatt aaaaacgccc ctttcatacc ttcttgttat
     9901 ttattttacc tttaattgta aaataagaaa agaaaagcac tctttttttc caataaaata
     9961 gggctgtgac aaaagtcgta tcacagctcc tttttccgaa taaacggcgt tcttgaagct
    10021 gatcacttct gtcacaacct cccttaaatc tgaatctata ttttttggta tttgttttta
    10081 tttgcttgcc tattcgacaa attcaaattc aaactcaccg atacgtacaa ggtcgccatc
    10141 tttcgcaccg cgtgcccgaa gagcttcatc cacacccata ccacgtaatt gacgagcaaa
    10201 acgcatcact gtttcatcat gatcgaaatt cgtcatttgg aataattttt cgatcttctc
    10261 accagataag atccacgttg catctgaatc acgatcgatt tggaactcag gaccttctgg
    10321 attgaatcca tagtgtacag tttcttcttc cagttcttct tcgtacaatg ggaattctgg
    10381 cgttacttct aacaaatctg ctgtagcatt caataacgcg tccaatcctt gtcgagtcac
    10441 tccagaaatt ggaaatactg ggatgtcatc agcaaattca tcttcttttt ccttgttcag
    10501 ctgttctttg aatttcacta gattttccgg tgcatccggc atatccattt tgtttgccac
    10561 gatgatttgc ggacgctcta gcaagcgtaa gttataagta gataattctt tgttgatggc
    10621 aagatagtct tcataaggat ctcgtccttc catcccactc atatcgatca catgtaaaat
    10681 tactcgtgtt ctttcgatat gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc
    10741 tccttcaatc aagcctggca agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac
    10801 cattcctaga ttaggtacga gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga
    10861 tgaaataacg gatagtaaag tcgatttccc gacagatgga aaacctacaa gtccaacgtc
    10921 tgccaatact ttcaattcta gttcgatttt tcgctcttgt cctggttcac cgttttcagc
    10981 aatttccggt gcaggattcc gaggagaggc aaaacggata ttccctcgtc caccgcgtcc
    11041 accttttgcc acaactagtg tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt
    11101 ctccgcatct cggacagtgg ttccttgtgg tactttaaca taggtatctt ctgaaccacg
    11161 accgtgcatc cctttactca tcccattttc acctggctgc gctttgaaat ggcgattgaa
    11221 ccgaaaatcc atcaatgtac gtaacccttc atcgacgatc aagatgacat cgccgccacg
    11281 accaccgtct ccgccagccg gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac
    11341 cattccgtct ccgcccttgc cagctttcac atcgatcgtt acttgatcta aaaacatgga
    11401 cataattaag tcctcctatt attcatttat ttatttgact gcctgaattt ccacaataaa
    11461 caaaagtctt acttatttta tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga
    11521 ttgtttacct tcttcttttt ttatcatttg gtaaggtttc caaccttttt tctgctacca
    11581 agtataattt tttgacaaaa tattctttgc gtagcagaat aacagtgtat taattgtatt
    11641 aattgtatta attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata
    11701 tgacagtaaa agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca
    11761 tcaaagaagt ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta
    11821 tgttagcaca attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg
    11881 caacagaaga ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg
    11941 caagcaaaat cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt
    12001 tttatacatc tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta
    12061 tttctgcccc agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag
    12121 atgaaaacga caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg
    12181 cttatttctt aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct
    12241 acacttccac acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc
    12301 gttcagctgc tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag
    12361 ttatccctga gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg
    12421 gttcattaac tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg
    12481 aagcaatcaa aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg
    12541 tttctagcga tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag
    12601 taacaactgc tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg
    12661 gatttacttg ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat
    12721 caatcgataa aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct
    12781 acttttaaac tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat
    12841 ttttcaggat ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct
    12901 tttggtccct tcgttgcacg atagacctta tctaacattt caaatggtac aaatgtatct
    12961 tcgtctccat gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt
    13021 gcttcaccga aaaagtagcc agcacggact tttgtcacta gactcgttac ttgcataagc
    13081 ggaaatgctg gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa
    13141 gaataaccgc aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc
    13201 atcataactg ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca
    13261 ttgttttcta gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat
    13321 ccaatgtaat ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa
    13381 cccatatcat gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca
    13441 tgagccacaa gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat
    13501 ttcagaccgt cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat
    13561 ttatgtgcat ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag
    13621 tctttctcag aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca
    13681 acaatcagag ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca
    13741 tctcatttct cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc
    13801 aatgttcatt tttataaccc gcgaattgta aaattaagtt agaaaaataa aaaggcattt
    13861 atggtacact caaattgtat ttccgacgaa agaaaacaaa ggagtgtaac cataaatgac
    13921 ctacaaacat cttaccatag acgaactgac aatgatagaa tcatattatc ttcaacataa
    13981 taagccggtt gaaatcgcta accgaatggg acgtgctata caaactattt ataatgtagt
    14041 caataagttc aagcaaggca agactgctct tgattattgg caccagtata aagaaaataa
    14101 gaaaaaatgt ggtagaaaag tcattcaatt acctgctcat gaagtagatt acattaaaga
    14161 gaaagtcact cttggttgga cgcctgacgt cattatcggg cgaaaagaaa gg
//
LOCUS       DAPBCF010000060        14118 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.061, whole genome shotgun sequence.
ACCESSION   DAPBCF010000060 DAPBCF010000000
VERSION     DAPBCF010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.061"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..556)
                     /locus_tag="RD508_002321"
     CDS             complement(<1..556)
                     /locus_tag="RD508_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HDT7736859.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGA"
     gene            complement(572..1051)
                     /locus_tag="RD508_002322"
     CDS             complement(572..1051)
                     /locus_tag="RD508_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HDT7736860.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1057..2081)
                     /locus_tag="RD508_002323"
                     /pseudo
     CDS             complement(1057..2081)
                     /locus_tag="RD508_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2098..3204)
                     /locus_tag="RD508_002324"
     CDS             complement(2098..3204)
                     /locus_tag="RD508_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDT7736861.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="RD508_002325"
                     /gene_synonym="adhC"
     CDS             complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="RD508_002325"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDT7736862.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="RD508_002326"
     CDS             complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="RD508_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDT7736863.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="RD508_002327"
     CDS             complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="RD508_002327"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDT7736864.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8175..8873
                     /locus_tag="RD508_002328"
     CDS             8175..8873
                     /locus_tag="RD508_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDT7736865.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9041..11680)
                     /locus_tag="RD508_002329"
     CDS             complement(9041..11680)
                     /locus_tag="RD508_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7736866.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(12299..13330)
                     /gene="queA"
                     /locus_tag="RD508_002330"
     CDS             complement(12299..13330)
                     /gene="queA"
                     /locus_tag="RD508_002330"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDT7736867.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            13523..>14118
                     /locus_tag="RD508_002331"
     CDS             13523..>14118
                     /locus_tag="RD508_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7736868.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
BASE COUNT         3959 a         3096 c         2543 g         4520 t
ORIGIN      
        1 aagcgcctac gagataacct cccataaaca aagcagagat cgaagcacca ccagcaacaa
       61 gtgaatacat gataaaagca gtacttggag gaatgaccat acctgtcgga gctgacgcga
      121 tattgaccgc tgtcgcaaac ttccggtcat atccttcttc cacttgctga gggatcaaca
      181 ctccaccaat cgcggtagaa gcggcaatgg ccgagctaga gatggaacca aataaagcat
      241 tccctaacac attcgtatga gccaaagccc ccggcacgcg cccgacgaac aacatcgcaa
      301 aatccactag tttcttagct atccctccat tattcatgat aatgcccgag agaacgaaaa
      361 acggaatagc gatcagcgaa aaactattga tacttcccac cattttttga gctgaactaa
      421 aagcagaaac atcaaacggt ataactaaca ataaagtcat catcgatgag aatgcaatac
      481 ttatagcaat cggcatccct aatacaagca acacaacaaa tacaaaaaat aacactaatc
      541 cggcttctat tgccatttta ttcctccatt tttatatttt ttcttgaatt gctggcttgt
      601 tgcttaatgt atcgattaga ttgatcaggc tatagataat gatgagtacc cccgatacag
      661 gtactgacag ataaacatat cccataggaa tacttaaaga aggcgagatc tgccccattg
      721 tcaatgtgac agcattccat ccgccataca ccatgatcat cgcagcaaat accagaaata
      781 aactttgaac aacaacttct aaaattttac tttttttgcc agttaatttt tcacttaaaa
      841 ccgttacggc taaacgtgct ttttgtccca caacatacgc ggaagacaac atggcaaacc
      901 agacaagacc gaatcgaaca agctcttccg tgaccgtatt tggatttcct aaaaccgttc
      961 tggaaaatac ttgccataaa acaacagcga ccatcccaac aagcaaaaca gctcccagga
     1021 tctctaatac cttgtttaaa atcattttca ttacagctac gctccttgct cttggatctt
     1081 ttgataaagg tctttgtagg taggatcgtt tttgaatata tcatgaagtg gggcaactgc
     1141 ctctcgaaac ggtgtattat ctacatcatt gaattggact ccatgttctt cttgtgctaa
     1201 agctttttct tcttcaattg cttttgcaaa agcttcaatt tcaaaaaccg ttgattcttt
     1261 cgctgcttct tcaatggctt tttcctgttc atcagttagc tgttctttga tggcatcatt
     1321 catgatgatg atatctggca cacgtgtatg ctcatcatag gaatagtatt tagctacccc
     1381 gccatgtcca gctgtataca agacaaattc attgttttct gatccgttga tcaaattgga
     1441 ttgaagagac gtgtacactt catcacttcc cataggtacg ggcgaaccgc ctaaaagctc
     1501 taccattttg atagcggttt cgctttgcat cacacggatc ttctttccct tcaaatcttc
     1561 cggcgtatgg atcggaccgt ctaccatata aaagctgcgc tgaccagaat cataataggt
     1621 caatccggta aatcctaaat ttttggtcga ttggtagatt ggctccatta tttcttcatt
     1681 atccatcacc ttaaagaaat gttcttcatc attgaataga taaggaacgg aaaaaatcga
     1741 ataatcttta gagaaacttt ccaacgctga ggcacttact tttgtgaaat ctactgctcc
     1801 tgactgtgtc aattcgatca gttcacgttc tccacccagt tgtccatctg ggaaatactg
     1861 gatctgtacg gaaccatctg ttttttcttt tactaaacgc ccaaattcat tcattgcatc
     1921 aattactggc tgttgcttgc ataagcaaag cgcaaggtaa ctatctcatt tacgtctgca
     1981 tctgcgacag ttgccacact agaattattt ccgcagccgc ttagacctag cagacctagg
     2041 ctaagcgaac ttgctgcaaa cagcagtgat gtttttttca tatgggtttc ctttctttta
     2101 acaataagag acgagcaatt ctgtcaaaca aagcaccgtt aacgactgtc cataaggcat
     2161 tgctgtgatt ccgatattcc gataaaaatc taaactgtcc cccattcctg tcccgattga
     2221 aacgttttga acttctcctt tttcatcgat ttgttcaagc aatccttgga tagcacgata
     2281 agcgacttct ttatattctt gtggtaaata acgtttatgg accgctttca aaataccgta
     2341 agcaaatcct gcagttgcag aagattctac gtaagaagaa ggatcatcca acaacgtatg
     2401 ccataaaccg ctttcagact gataagtttt taatgcacgc acttgtgctt caagtgtttc
     2461 gatcaataat ttgcgcaatg catcttcttt cgataattct aagatttcaa tgatctctgg
     2521 aatagcaatc gtcaaccagc agtttccacg agcccaaaat gcttcggcat agttatgatt
     2581 tccttcaaac gtccagccgt gataccacaa tcctgttcgt ttatccatca agtatttgat
     2641 atggatcata aactggtaac gagcttcttc taaatattct gggcgattca acagtttccc
     2701 gatttttgcc aaaggaagca ctgtcatcat caatgtatcg tcccacaact gattcttatt
     2761 ttccggtcca tatgtggcat gctgtaaccc gtcttcattt gtccgaggca tgtcattcat
     2821 gacccattct gcccattgtt ctaaataagg caaatagcgt gaatctttcg tgtcttcata
     2881 caagtaagcc atagtcaata gcggtgccat tgtattgacg tttttgggcg gagcgccttc
     2941 ttccatacga tcctcaaacc attcattgac cacttgataa gcgcgaggat tttttgtcat
     3001 ctggtaattt ttataaatac catatagacc gacaccttgt ggccaattcc acactgtcca
     3061 gcttttgtca tctactttca gtccatcaaa gtccaacaaa aattcaccat tatcgtcttt
     3121 gatcgttgtc aggttttcaa cgagcaggtc aattttttct ttcactaatt ctttaggtac
     3181 aaaaatctct tctttaataa tcatctttac gccacctttt taaacgcttt cattttatat
     3241 ccttaatata gcagtaatac cgtccactat aaatatcgct ttttgaacaa aaactgtcta
     3301 aaattgacct aaatgttaaa taacaaaagt aactttcagt tacttggaaa ttaaaaaaag
     3361 aacttggaga aacaacgttt tccaagttct ttttcatcta ttttcttatc ttttttctac
     3421 gctttctttt gcttatccgt tgtaagcatc aatgatgatc tgtttcaatt cagagatcaa
     3481 tggttctttc ggattagctg tcgtacattg gtcttcgtaa gctaattcag ccatacggtc
     3541 tacggttgta tctagtgttt cttgtgtgac tccttgagct tttagactca tgttgatgcc
     3601 gacagatttt cctaattcat aaacagccgt tgctaaagct tcgactaatt cctctgttgt
     3661 ttcgcctttc agacctaaga attttgcgat atctgcgtaa tctgtatctg cacggaaata
     3721 gtcatattta gggaacatcg catgtttttg tggatctttt gcattatagc ggataatatg
     3781 cggtaaaaga atcgcatttg tccgtccatg agggatcccg tattccccgc cgattttatg
     3841 tgcgactgag tgacaaatac ctaggaatgc gttagcaaac gccataccag ccattgtaga
     3901 agcgttgtgc attttttcac gtgattccat atcaggtgtt tttactgatt tttctaaata
     3961 gtcaaagact aacttgattg cttgtaggct caatccacgt gtataatctg aagccatgac
     4021 tgaaacatag gattcgattg catgtgttaa cacatccatc ccggtatctg ctgtgacaga
     4081 tgctggaact gacatgacga attgaggatc gacgattgcg acatctggcg tcaatgcata
     4141 atctgctaac ggatatttca catgtgtttc actgtcagtg atgaccgcaa atggcgttac
     4201 ttcagaacca gtccctgatg ttgtcgggat acatacgaat tgtgtttttt ctggtttgtc
     4261 gatcttatat gtccgtttac ggatatccaa gaatttttgt tttgcaccaa agaaagatgt
     4321 gtctgggtgt tcatagaaca tccacattcc cttagctgcg tccattgcag aaccgcctcc
     4381 aagagcgatt actgtatctg gcttgaagtc tgccatcagt ttcgttcctg cgtatacggt
     4441 atttgtcgat gggttcggtt caacatctga gaagacttcg atcttcacat catttttacg
     4501 tcgtgccaat acttcacgaa ctgtatcgca gtaaccgaat tggaccatac cagggtcaca
     4561 aacgatcatg acacgttcaa cgttttccat tttctctaag tacaatagag agttcttttc
     4621 aaagaagatt tttggcggta atttgaacca ttgcatgtta tttctccgtt tcgctacagt
     4681 tttgacattg attaagttta cagcagagac gttacgagaa acagagttct taccataaga
     4741 accgcatccc aaagtcaatg acggaatcat ttcgttatag atatcaccga tgccgccttc
     4801 tgcagatggt gtattcacta aaatacgaca agctttcatt cgaagaccga atttgacatg
     4861 caactcttcg ttttctgaat ggataactgc tgtatgtcct aatcctccaa gattcaacat
     4921 accttcacac aaatcaaacg catggtccgt gttgttagct ttgatcatgg caagaactgg
     4981 agaaagtttt tctcttgata gcggataatc tgggcctacg ccttccaatt cagcaatcag
     5041 cattttcgtt ccttttggta cactgattcc tgccaatttt gcgatttcca tcgcagaatg
     5101 tccaacgatt gatggattga ccgcatattt tccttcgttc atcactgcat cttctaattt
     5161 ttgcaattca tctggtttta cgatataaac ttggtgtgct tggaattctg cttttactgc
     5221 tgcatagatt tctttatcca cgatcacagc ttgttcagaa gcacaaatca ttccattatc
     5281 aaatgttttc gaaacgatca aatcgttcac tgcacgttta atttttgctg ttttttcaat
     5341 ataagctggt acgttacctg gacctacacc taaagctggt tttcctgtag agtaagcaga
     5401 cttgaccatt ccagctccac ctgtcgctaa gacgatcgcg atacctggat ggttcattag
     5461 catagaagtc gcttcgatcg aaggatgttc gatccattgg atacaatttt caggagctcc
     5521 ggcagcgata gcagcatcac gtaccactcg tgctgcttct gcagaagatt tttgggcact
     5581 tggatggaaa gcaaaaacga ttggatttct tgttttcaac gcgatcattg atttgaaaat
     5641 cgttgtggaa gtcggattcg ttgttggagt tactccgcaa accacaccga ctggttcagc
     5701 aatttcaatc aacccttttt ggacatcttc attgatcaca ccaactgttt tatcatgttt
     5761 gatattatgc caaatatatt cggacgcata catatttttg attgctttat cttcgtaaac
     5821 accgcggcct gtttcctcta cagccatctt cgctaatggc atatgttgat ccaaagctgc
     5881 cattgccatt tcatgcacga tatggtctac tttttcttga tcaaagcttt ccatttcttt
     5941 caatgctgca tttgcttttt ctgccaaatc atcaatcatt gcttgtacgt caattgtctt
     6001 cgttttttct ttttctatta ctttagccat cattatcctc ctaatgggtc atggttattt
     6061 gttaaataat tcacatgtat atcatacaat atttattttt ctatgtaaac acttttttgt
     6121 gatttttttc acagttattt ttaaatataa aattgcttta tttacaggtg tttgtataga
     6181 aaaatatata aagttattta ttattattta tatgacacac ccgattattc aatattgagc
     6241 aatatatccc atgctcttat ctctttcttt tttgaataaa aaatgaggta ggacatcttt
     6301 ctgccctacc tcgtctttaa ataagctttg atacttattt ttcttccttc tcttctgtct
     6361 cttccagcgt ttctgttgtt tcagttttta cttcaactgt ctcagctggt tcttctgttg
     6421 tttcaacagt agtcgttgca tcatttgtta cgacagtccc tggtttgacc gttttgattg
     6481 ctgcacgatc gtactcaagg aagatccctt cgcagtctaa aacaactgtc cgtttgtcat
     6541 tgtcgatttc tgaaacaact ccatgtaatc cgccgatcgt tacgactgaa tcacctggtt
     6601 tcatgctatc taacaagttt tgacgttctt gctgttgttt cttttgcgaa cgtgacataa
     6661 aaaaccacat tgctaatagc gcgataaaca tcacaagcat tggtaatgtt cccatttttt
     6721 tcacctcact aattctgtat ctacaaaaaa cactttagca gaaaaatgct gataacacta
     6781 gttttttact taatttttaa aagattttcc tttagaagct ttttgcgttt tctttattga
     6841 acccgtattc ttcaaaaaag gcttctctaa attcaagcaa attatcatcc atgattgctt
     6901 gacgtacttg tttcattaga ttcaacaaga agtataaatt gtggtaagaa gtcaaacgaa
     6961 tcccaaatgt ttcatcacat ttgatcaaat ggcggatata ggcacgtgta tagtttttac
     7021 atgtataaca atcacatttc tcatcaattg gacggaaatc atgggcatat ttcgcatttt
     7081 tcactactag acggccttga gaagtcatac atgtgccatt tcgagcgatt cgagtaggca
     7141 agacacagtc aaacatgtct actccacgga taacaccatc gatcaatgaa tcagcagcac
     7201 cgacacccat caagtaacgt ggtttgtttt cggggatcaa cggtgtagtg aattctaata
     7261 cacgattcat ttctgattta ggttccccga cagataaccc gccgattgag taaccaggga
     7321 aatccatccc gactagatct ttcgcgcttt gacgacgaag atcttcaaac cctgctcctt
     7381 ggatgattcc aaataatcct tgacggtctg gattagcatg agctttcaat cctcgttctg
     7441 cccatcgaga cgtacgttct actgattttt tcacgtagtc gtaactttca tcgaatggtg
     7501 gacattcgtc aaaactcatc atgatatcag agcccaattt attttggatg ttgattgctt
     7561 tttctggtga taaaaacata cgcgaaccgt tcaagtgatt tttgaaatgc acgccttctt
     7621 cttcgatatt ccgcatatca cttaatgaaa aaacttgaaa gccgcctgaa tctgttaaaa
     7681 tcggttgatc ccagttcata aatttatgca gtccgccagc ttcttctact aagtcttcac
     7741 cagggcgtag ccataaatga tatgtattac ttaaaataac gccagcaccc atttctttca
     7801 actcttctgg ggacattgtt tttactgtag ctaatgttcc tactggcatg aacattggtg
     7861 tggggaaagt tccgtgtggc gtgatcaatt cccctaaacg cgcgccagta tgtttttctt
     7921 tcttgattaa acgatagcga atggcaggtt gcgtcattca tttccctact ttctatataa
     7981 aatatcttga caactcccac catcataatc gtttcaagtg ctttttgcaa gttccctcgg
     8041 cttccttcta ctttatttaa tattcttttt tttatccttt ttttatgaat aacaaaaaaa
     8101 agaaaaacat tatgacagaa atattttttg atacatggta tattggtgtt attaaagaaa
     8161 aggagggaaa aatcatgcaa tcttctgcag aattaaaacg ccaagcaaaa gagagtctaa
     8221 aaggacgttg gggacaagct gttttactaa atctaatccc tacattgatt ggtattgcta
     8281 ctattcttct tattatgatt cctattatct tgtttgccac caccatatat gatggatcag
     8341 cgagcgtctc agaagcgaca acttcaggag gcggtagttc aggaggcggt ggcggaatta
     8401 tttccagcat cattagcgct ttgttcatga gcggtatttc ttggacttat cttgatattt
     8461 tacgtggaca aaaagatcag atcgaaccat tcaaagatgc atttcgtgga ttcaaaggtt
     8521 tgtttatcgg cggagtgatc agcttagctg tgctgatctc gatctttaca acattatggg
     8581 gtttgctatt agttattcct ggaatcatta aaagctattc ttattctcaa agctatttta
     8641 tttactacga tatcgtccaa gaaacaggac aaacacctaa agtactggat acgatcactg
     8701 caagtcgaaa attgatggat ggttataaag gacaactttt ctggttagat ctttcattta
     8761 tcggctggca tatcttagca ttagcaactg ctggtattgg ttatctatgg ctcagcccat
     8821 acatttctgc aacaaaagca gcattttatg aacaattgcc aaaagatatt taaaagagag
     8881 tgtgacttgt gaccgagggg gtggcaggag aacaccgttt atcgagaggc agtaaaagaa
     8941 acattcagcc cattagcaaa aaggaggtgt gacaacattc atgtcacacc tcctttttgt
     9001 atagttccag taaaaagaaa atcaacttag aaacagttaa tcattcctct tcttctgctt
     9061 ccggtaatcg atggaacttg atcagttcat tcaccgcgat tggtacgata gataaaatcc
     9121 ctaccaagaa ccagtgattc aaactgatgt gtactaggcc gaatagttct tgcgtaaatg
     9181 gcagcaaagc aacagccgtt gtaatagcta atgccagtaa cgccatttct accaaagctt
     9241 tattggtcgc taaattgact ttgaagatcg attggctgct gcgtacattg aacacatgca
     9301 gaatcgatga ataagctaag atcaagaatg caacagtttg accgacatgc tgacttgcgt
     9361 ctacccatgg gctgatagta tcgacataac tacctaaata ataaccaaac aaggttacga
     9421 tggtgaagac ccctgcattt atggcaattt tttgcaataa acctcgagca aagatccctt
     9481 catttttcgg aatgggtggc tgatccatga tgccgtgttc cgctggctct cttcctaaag
     9541 caaatcctgg aagtccatca gcaactacat tgacaaacag tagttgcaca gctgtaaatg
     9601 gtgctcccca tcctaacagc atcgcaatca aaacaataaa gatctccgaa atattacagc
     9661 ttagcaaaaa gttgatagct ttacgaatat tctgataaac cgaacgtcct tgactgacag
     9721 cgtctacgat cgtcgcaaag ttgtcatccg tcaaaatcat atctgcggca ctttgcgcca
     9781 catctgttcc tgtgatcccc atggcacacc caacgttact tgctttcaac gctggtgcat
     9841 cattcacacc atccccagtc atcgctacga ctgcacccgt acgttgccaa gatttgacga
     9901 tccggatctt gtcttctggc gttacccgag catagacaga gagagctttg acacgcgcat
     9961 ctaattcttc gtctgataat tgatgcagtt ctgatcctga aagtgcttct gacggatcat
    10021 tcaagatacc taattctttc gctatggcac tggcagtcac cacatgatct ccagtgatca
    10081 tgactgtttt gatgccagcc tttttcgctc gcttgattgc tcctttactt tctggacgtg
    10141 gtggatcgat cattccgatc agaccaatca aacgtaagtc tttttccagt gcttcagaag
    10201 aaatatcttg cggttcttcg tcataagtag cataaccaac agcaatcact ctcagtgccc
    10261 gtttaccaaa gcgatcatta acgatcgccg cttgttctac atcgcctgaa ctaaagcgcg
    10321 gagcaagaac atcgaatgct cctttggtga ttgagatgta tttttcgccc atttggtgaa
    10381 ctgttgtcat catttttcgt tcagaatcaa aaggaagctc gtttactcgt ggatattttt
    10441 cttctaattc tgcctttgta tgataattct cttcaacagc ccttacgatg gctacttctg
    10501 ttggattacc tttgataaca aggtcgtcat cttcttgctc gaccgtcaca tctgtacata
    10561 gtgcagccat tttcaatatt tccatcgcgc tgttcgtcat tgaatcttcg atattcgtta
    10621 cttcatcttc tttgctccat acccggcgga cgcgcatttc attttgtgtc agcgttcctg
    10681 ttttgtctga gcagataaca ttagcggttc ctagcgtttc aactgctggc aactgtcgga
    10741 tgatcgcatg tttcctcgcc atcttctgca caccgtatgc aagtgtcaac gtaacaataa
    10801 cagtcaaggt ttccggtaca gctgcaacag ccaaggaaat cgaagtcatg aacatctcaa
    10861 ggagtggttc tccttgcagt tcaccaatca caaatactaa agccgcagcc gctaaagcga
    10921 tcatactgat tcgtttgcct agctgattca atcggacctg taaaggtgtt ttttgcatag
    10981 tattttcgtt caaaagatcc gcgatcttac ccatttctgt agccatgcca atggcagtga
    11041 cgatcgcttt cccacgacct gcagcaaccg tacatccttt aaataccata ttaagttggt
    11101 cacctaatga ctcatcttct tcagcaataa atgctgcatc tttttcaact gcttcacttt
    11161 ctccagtcaa cgccgattct tctacacgta attgtgatgc ttcgatcaaa cgggcatcgg
    11221 cagaaatagc atcaccggac tctaaaacaa gaatatcacc cactaccagt tgctctgact
    11281 caacagtggt cactttgccg tctcgtatga cagttgccgt ttgtttattc atatcttgca
    11341 aggattccag tgctttttct gcgtttcctt cttggacaat cgccaatacc gagttgatca
    11401 caacgatagc gatgatcagc agtccttcaa ataaatcccc atgttctgta gcaaatgcgg
    11461 tataaaagga aatcaccgct gctacaagaa ggatgatcgt tgtaaaatcg gacaagcttc
    11521 gaaagaattt tttgatcatc gattctttcg gcgcctcatc gaatttattc aatccctgct
    11581 tttttcgccg ttcatccact tcttgtgaag acaacccagt atctggatct gcttctgtta
    11641 ccttctttac ttcttctatt gtctgcttgt attcttccat cctattcctc ctttaaaatc
    11701 ttcgtacaaa aaaaggtact tattttacta taacatcctt tttttattta cttcaaataa
    11761 agggcttatc gattatttgt taagaaagcg taaaatttaa agtgcttata tttgcaaacg
    11821 ctaccaaagg atgctattat atagatgtaa ggaaggagga taccatcaaa tagacagaag
    11881 aatttctcga tagaacagtg taagcaaaca aagttgttag aagtacaggt ttcacccaga
    11941 catgcgtgta gagtacaaac ctataaatag tgaatgcgta tggatgtttg gatcacgaag
    12001 tatccgaaac aagaagtaat gcgatacgta acaattgaat aacgtaaacg tctgaaaatt
    12061 gaataggaac aagagatgtt tcaaatgttg aagatgtaac gaaaacaaaa tttttgttta
    12121 acatgaagaa attcaacacc gtgctttgca tgtatgatgg aaagttacaa tcatttctgt
    12181 ttatttgaat ccttccgagg tacaagaaag ccgagcttat cgagagctcg gctttttctt
    12241 tgtcataaaa tctttgtaaa gcttttttgt tattcaaaac tagcggcttt tcataacctt
    12301 atttcacgaa catcgcatct ccaaaactaa agaaacgata gcgctcttca atcgcatgct
    12361 ggtaagcaga taaagtcaat tctcttcctg caaaggcact aactaacatg actaaagtcg
    12421 attttggcaa atggaaatta gttgagaaag cttctaccac tttgaattca tagccaggcg
    12481 taatgaaaat atcagtccat ccgctgtctg ctttgatttc tccattaaat ttcgttccaa
    12541 tcgtttctaa tgttcgaatt gaagttgttc cgacagccac gattttcccg ccatttttac
    12601 gtacttggtt caatcgctca gccgcttctt ccgtcaaacg gtagaattca ctatgcatat
    12661 ggtgttcttc aattttatct acgctgacag gtcggaatgt acctaaccct acatgtagtg
    12721 tcagatagac taattcaaca ccctttgctt cgatctcatc aagtaattct ttcgtaaaat
    12781 gcaatccagc tgttggcgct gcagcagaac cattttcttt cgcatagaca gtttgatagc
    12841 gatctgggtc ttccagacgt tctttgatat atggaggcaa tggcatttct cccaatgatt
    12901 caagaatctc tagaaaaatt ccttcatact caaagtcaat gatccgtccg ccgtgttcca
    12961 attcttcttt cactactgct tgcaatctgc catcaccaaa agagattctt gtcccaactt
    13021 tggcacgttt cgcaggtttg atcaatgtct cccacgtatc tccttgtgta ttcgttagaa
    13081 gaaggacttc taaatgcgca ccagtatctg gtttttctcc atataaacga gcaggcagaa
    13141 ctcgtgtatt attcataact agcgcatcac caggctgtaa ctcttcaatg atttcatgga
    13201 aatgtttatc ttccatctct ccagttttcc gatccaaaac aagtaaacga gaatgatcgc
    13261 ggtcttttaa tggtgtttgt gcgattaatt cttccggcaa gtcaaaatca aaatcttctg
    13321 ttgttaacat atcgtcactc actttctatc atgtgcttca tcattctatc atgtttttcg
    13381 ttctgttggc aaaatcagca ctttttcact tctatttttt gttttcctaa ataaaaaaac
    13441 taccctattt gtattttttc attgttttag gcatactagt aatagatagt tcttcattga
    13501 aaatagaaaa agaggtggca ccatgattga atttcaaaat gtgtcaaaaa tttataaagg
    13561 tggaaaagtc gctgtagagg acgtcaatct ttcatttgaa aagggtgagt tcatttgttt
    13621 tatcggtacg agcggaagcg gaaaaacgac gacgatgcgg atgatcaacc gaatgactga
    13681 tccaacacaa gggaaaattt tgattgatgg aaaatccatc caagaaattg atccagtgga
    13741 attgcgacgt cagatcggct atgttatcca aagtattgga ttgatgcctc acatgacgat
    13801 ccgtgaaaat atcactcttg tccaaaaatt gttgaaagtc agtcaagaag aacggaataa
    13861 aacagctgaa aaaatgattg atcttgtgga attgccccgt gagatgttag atcgctaccc
    13921 acatgaatta tctggtggtc agcagcagcg tattggagtc gttcgtgccc ttgcagcgaa
    13981 tcaagatatc atcttgatgg acgagccatt cggtgcgctt gatccaatca ctcgtgattc
    14041 cttgcaagac cttgtcaaag atttacaaga gcgtttggga aaaacgatcg tatttgtaac
    14101 ccatgacatg gatgaagc
//
LOCUS       DAPBCF010000061        14004 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.062, whole genome shotgun sequence.
ACCESSION   DAPBCF010000061 DAPBCF010000000
VERSION     DAPBCF010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.062"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            39..1340
                     /locus_tag="RD508_002332"
     CDS             39..1340
                     /locus_tag="RD508_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDT7736869.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            complement(1418..1567)
                     /locus_tag="RD508_002333"
     CDS             complement(1418..1567)
                     /locus_tag="RD508_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736870.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            1963..2163
                     /locus_tag="RD508_002334"
     CDS             1963..2163
                     /locus_tag="RD508_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7736871.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            2731..3294
                     /locus_tag="RD508_002335"
     CDS             2731..3294
                     /locus_tag="RD508_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736872.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(3355..3720)
                     /locus_tag="RD508_002336"
     CDS             complement(3355..3720)
                     /locus_tag="RD508_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736873.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(3796..4041)
                     /locus_tag="RD508_002337"
     CDS             complement(3796..4041)
                     /locus_tag="RD508_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7736874.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(4111..4365)
                     /locus_tag="RD508_002338"
     CDS             complement(4111..4365)
                     /locus_tag="RD508_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736875.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(4529..4852)
                     /locus_tag="RD508_002339"
     CDS             complement(4529..4852)
                     /locus_tag="RD508_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736876.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            5039..5112
                     /locus_tag="RD508_002340"
     tRNA            5039..5112
                     /locus_tag="RD508_002340"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5073..5075,aa:Ile,seq:cat)
     gene            complement(5497..5994)
                     /locus_tag="RD508_002341"
     CDS             complement(5497..5994)
                     /locus_tag="RD508_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7736877.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(6034..6843)
                     /locus_tag="RD508_002342"
     CDS             complement(6034..6843)
                     /locus_tag="RD508_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7736878.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            7177..8034
                     /locus_tag="RD508_002343"
     CDS             7177..8034
                     /locus_tag="RD508_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HDT7736879.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            8027..8929
                     /locus_tag="RD508_002344"
     CDS             8027..8929
                     /locus_tag="RD508_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HDT7736880.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            8962..9312
                     /locus_tag="RD508_002345"
     CDS             8962..9312
                     /locus_tag="RD508_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDT7736881.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            9361..10284
                     /locus_tag="RD508_002346"
     CDS             9361..10284
                     /locus_tag="RD508_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDT7736882.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            10362..11255
                     /locus_tag="RD508_002347"
     CDS             10362..11255
                     /locus_tag="RD508_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7736883.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            11293..11856
                     /gene="amaP"
                     /locus_tag="RD508_002348"
     CDS             11293..11856
                     /gene="amaP"
                     /locus_tag="RD508_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HDT7736884.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            11870..12058
                     /locus_tag="RD508_002349"
     CDS             11870..12058
                     /locus_tag="RD508_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HDT7736885.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            12071..12973
                     /locus_tag="RD508_002350"
     CDS             12071..12973
                     /locus_tag="RD508_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7736886.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            13005..13247
                     /locus_tag="RD508_002351"
     CDS             13005..13247
                     /locus_tag="RD508_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7736887.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(13503..13874)
                     /locus_tag="RD508_002352"
     CDS             complement(13503..13874)
                     /locus_tag="RD508_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736888.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4917 a         2398 c         2625 g         4064 t
ORIGIN      
        1 aattgaatca ccacaacaca atcaaaggag cgttctgtat gcctgatctt catcatatca
       61 aactactact tggaatcaaa gataaaaaca ttttcatcac aaatgtggaa tcgaagagca
      121 ttaagaatat caagagtctt gttgtttctg cgacgttaag taaagaaatt cgtcgctgtc
      181 ctttgtgtaa acagatgaat catgaaggca tgatcgttaa gaacggaaag aaaaaatcgc
      241 tcattcaact taataaatgt gcgaaccaac tgacttatct tgctttagcg aaacaacgct
      301 accactgtcg tggctgccac acctatttta cggcgaatac ctacattgtc gatagaaact
      361 gctttatcgc taaacaagtg cgctataaaa ttttagaaga gctaactgaa aaacaagcaa
      421 tgacgacaat tgctaagcat tgcggcgttt cttggtcgac cgtttctcgg acactcgctt
      481 ctctgatccc catgacaaaa gtaaaaagaa attggttacc gcgttgttta ttaatggatg
      541 aatttcgttc actgaaaaat caagtcggtc cctactcctt ttcttgtatg gatggcgata
      601 ctggaaaatt actggatatt cttccttcac ggaagaaaaa ggctctcgtt tcttatttta
      661 tgcaatttga acgacgcgca cgattgaagg taaaggtcat cgtgacggac atgaatgttt
      721 cttatgcctc tctgataaag gaatgttttc caaaggcaaa actcgttgtg gatcgttttc
      781 acattgtcaa acatctcatt cgtaaatttg aggatattcg cgtacgaatc atgaaaagct
      841 ttgatcgaaa cgatccaaca caagccaaat attatcgaca attaaaggcg ttgtctcggc
      901 ttctgatcaa acgacaggac aagcttgttt atgacaaatg gaccaaatgg cgcaattttg
      961 gttgggcgta tctcaccgaa agtgaagtgg tggatcgtct gctttcgatc tctgacgaat
     1021 tacgaatcgc ctatttttac tatcaagaaa ttcttcaagc gtttcacgac aaagaggcgg
     1081 acactttctt taaacttgta agaacgatgc ccaattccgt tccaaaagaa ctgcattcta
     1141 taaaaaaagc ttttataaac tatgaatccg gcattcgttt agccctcgaa ttgccttatt
     1201 caaatgccaa aatagaaaat ctgcataccc acatcaaagc attgaaacga gtcgcttatg
     1261 gctttcgaag ctttcggaaa atgaagacca gaattttctt actaaataat ctgattacct
     1321 atgaatcaaa aaacatctaa agtagaaaag gaattctacc ttagatgttc ttatctcact
     1381 ctatcagtcc tatttgacaa agagccgttt ccactcctta tgcagatttt tttaattctt
     1441 gcactgcttg ttcgatcgta acacctgtcg ctacatgatt ggtattttct ttgtcaaaaa
     1501 cgacaaatag attcaaatct gtatccaagg ttactcgata ttgtatatct ttgttataga
     1561 atgtcatagc cattctcctt tctttaaata cttgctgaaa ggcaacgaac gcgttgataa
     1621 cgaaattcca tttataagta taccaccaat tgaaaggttt tcatagttaa gaaattttaa
     1681 agtcaaaagt tgcagataaa agcaaataaa caagaaaaca aaaagtgaat caatcgcggt
     1741 tattcaactt tttcttcgat tcgaagacaa tagaagacaa tgaattttat atttcattgc
     1801 attatccttg tgttattaga aaaagcatga tatattaaat gagtaatcta ttttgaaacg
     1861 taatttgagc gatatatcta catagataaa actccttttg cctatcaaat atttattgca
     1921 acgaaaaaac gtacattgat acgtatcagg aggaatttat ttatgaataa cggtacagta
     1981 aaatggttca acgcagacaa aggttttggc tttatcactg gtgaagatgg aaatgatgta
     2041 tttgcacatt tttcagctat ccaaggtgac ggcttcaaaa ctttagaaga aggccaagca
     2101 gtgtcttacg atgttgaaga tggtcaacgt ggccctcaag caacaaacat tgttaaagct
     2161 taataaaaat tgacttttaa ccgtcttttc gaaagaaaag acggtttttt tgtacgaaaa
     2221 aattcattgg tcgttgaatg ggctgaatag tagtgtataa aacaattttg tggagcgtga
     2281 agcttttatg gtagaggaaa atacgaataa agtgatgttg ataaaaagat tcctatcttg
     2341 aatatgaatc gagatgtctt gaaaatgaat gagtttgacc aatcattatc ctatcgaaat
     2401 ttacagtttc gttcgattgg tctgtcaatt aatgaaaaag taaaaaagaa tatgttctag
     2461 gaagagggcg gcacatctaa atttttaagt aacggacagt tcaaatatca agcattgaaa
     2521 gaggctatcc tactgtttga aggaatacga atatataaaa acgacaaaga ggaaaaagta
     2581 gttcattaaa tcccttcaag tgatgaaaga atgagatcta ataaaacctg atctttcatc
     2641 tgttttttta ataacgtaat aattttttta ttttttgtgc tttcgccgtt attgtagagt
     2701 gatttagcat tcttattttt aaaaataact gtgttatata ttaaaaaagg cataatagtt
     2761 ataagctttt ttaaagaata tttagaaatt attaattttc gtctgaaaac aaaaaaagaa
     2821 agcgttatta ttttagtcta ttttcagggg gggaacctta tgataaaaaa actattttta
     2881 ctatcaatat taacgctagc aatggcaggt tgttctgact ctggcttagc aactgaactg
     2941 atcacaaaat caactgaagc cacgacagag gagttaaaat gtggaaacga tcacagtgac
     3001 tacagaggct taaatcgacg atgcatggga atattaggca gaagcaattg taagcatcga
     3061 tgtagtaatc gaagaaggtg tagaagaagc aacagaaaaa tcaaaagaaa gatcaaaaga
     3121 agcaatctgt gctgtgcatc gtatacagac gtcgaagatg cggtactttt aaaccacgtc
     3181 aggagatgtt catttatgtc tagggaagtt ggcgatgaac caaaactaga gtacgctttt
     3241 agttttgcac gtgaggatga agataaccct aaaacttacg acattttagc ttgatctaag
     3301 atggttaaag ctttttaatg aagtaagagg agatagaagg cttttctagt tatattaggt
     3361 aagataaatt cctttttgct ccaaatttgc taaacattct gctagataaa cttcatcgtg
     3421 ttccggataa atcggcacgt tgcgctctac agtaggtaaa tcaaaaaatg cttcgcatga
     3481 tttgccacga tacataggat ttttccactc tggtgctggg ctgtaaccac gtttttccat
     3541 ttcatccatg acaagctgat gatattggaa taatctataa ggagaatagt gaaaaacata
     3601 atccacagta gcatgtttct ttccccagcc atttcctctt aatgcacagc attcccgatg
     3661 ttgtcctaaa agctgttgac gaggaagctt tgaaatcaat ttttcatgcc ataatcgcat
     3721 agaaatgtct cctttatata tagattgtta accttagacg ttaaatgaaa aaaccagcac
     3781 caaggctgga aaaaatcact tcagtttgct tgctgtttct gagcgaccaa ttaggtaatc
     3841 aacggaaata tcgtaaaagt cagcgatata gattaattca atgatgcttg gaatttcttc
     3901 tccttcttcg tacttacgat atttgaataa aggaatactt aacgcgctag aaacagctac
     3961 ttgagataaa gatcggccag ttcttaagaa attcagacga caacgtaaag tatccagtaa
     4021 aatagcttct tcgatactca tttaatcacc tttcattata gtagaatagt tataatgact
     4081 atagaaagct acacatgcaa tcaatagtac tcaatgtttt ttatttaaac gtatcaaata
     4141 aagaatgacg atcaataaag acaaaaccag tcctgataat tcttctataa aaacactatc
     4201 gggttcaaag tagttgtaat taaaaacttt ccacataaag tagatagccg gaagagtcaa
     4261 aatagctaaa taaaaccgtt ctttgttcca attcataaga taaacaatac ttgcgaccag
     4321 tgcgaccgca ggcacccaaa acaaaactct caccaacgta atcatgtaac ggactcctca
     4381 acgattcata taataaaaga taacatgtta ttgcatacat cacaaatgaa atgctaggaa
     4441 aataaaagaa gaatagatca atgaaaaatg aaaaagcaga acagttttct gctgataagc
     4501 aggaactgtt ccgctgaatg tgtcttatct atcgagaaaa aatcaatgga ttgatatcta
     4561 agtaattcaa tacatataaa aagaggacga tcgcattcac taaaaaggaa agaatgatga
     4621 tcccatagcg aatggaaaca tatttaacaa atacttttgt ttgaatacgg gcatatcttt
     4681 ttcctttata gctgagcatc atgacaagaa gcaaaagggt aatcacacct tgaaaaatca
     4741 ttccaataaa cagaattcct gaggtttgat aatttaattg gagaaaataa gctgctgccg
     4801 caactaaatc gaataaaatc gcaataaatg gcaaaataat cactcctaac attgagaata
     4861 aataaaagaa taacattttt tctaaaataa gcaaataaaa attaaagtaa caaaatagtt
     4921 atgacacaag taaaagaaat aagaataaca atattatttt acttatattt tgaaacttgt
     4981 gagagtttgt cattcgtgct atagttgaaa agtaacaaaa ataaatttta tttatgatgt
     5041 acctttagct cagttggtta gagcagacgg ctcataaccg tccggtcgta ggttcgagtc
     5101 ctacaaggta cataagaggt tgtgaaaaag ctgccctgca tcaagtaata agaacagcca
     5161 agtaaaaaca gcttcttatg tttttacttg gctgttctta ttactgcaga tgcaagcttt
     5221 tgaataccgt ttaaggaaga ggttgtgaaa tcagcgtttt gacctgagta ttagcttaac
     5281 aaacggaaaa atagttcctc atattttgcc gtttgttaag ctaataccga gggtcagctg
     5341 attgaacacc atttaagaaa gaggtcgtga gcctgccgtt tcactctgtg tcataaaaaa
     5401 gccaatctac tttgatagaa aaagcacgta ggactaaaac agttctgcgt gcttttttta
     5461 ttgtgtgtta aatatcgtaa atgaagatag atatttttat gattcgacga tagagacgtt
     5521 gaaatctttc aacagctcta aagcggattc tccgtgtttt ctactggaga ctaacattgg
     5581 atcaacaaaa aagtctgctt caggaaaagc actctgcagg cctatcagat tagagagtac
     5641 acacaagttt gtttcaatcc cgactacttc gatctctttt tgttcttctt tgctttcaaa
     5701 taaagtttcc tggatttcag ctaaagtttc aggtggaatc gtaaagtaat actttttaat
     5761 cactcgttca ttttcttgtg gagaaagaag agggatcaat tgcaaatctt ctcgttcttc
     5821 ttctttgtcc ttcagttcaa ctggtatatc ccgtgtgaag agaatatatt cattattttg
     5881 gcgtgcttta gctaatcttt gagcaatacg ttctgccaat tgatctgact ctggaatata
     5941 aaattcgctg tttggatcaa gaatatgatt ttgcatatca ataataacta acattttctt
     6001 tcctcctaca ttcatatcgt cattttattc tttttaatag aagtttttta aaatataagc
     6061 aacaccagct tcttcattcg tcagtgttac ttggtttgca atttctttta cttgtcgctg
     6121 tgcattcccc atcgcaatac tcaacccgct gtaattcaac atagcaatgt cgttttcttg
     6181 atcgccaaaa gccatgatgt cactcgattc gattccaagg taatccgcca gaaaaacaag
     6241 tgaatgagct ttagtgatac ctgtaggcgt gatttctaag aaatgcggat cagagaatac
     6301 tgattggata ccatctgctt gcagatctct ttgtagcttc tgtagttttt cttcactctt
     6361 atctgttaat gctaatttaa gatagctaag agaaggatct tccaacatat ttaaaatttg
     6421 atcaaaagaa tggttctgta aattgaaatg ttcataataa gggtcatctt tgactagatt
     6481 tgattcatcg aatgtcagct gatcatcttg ggtttctcgg ctagcaatga tggatatttt
     6541 cgcttcttga gcatagaaga aggcttttct cagtgtatcg ctatctattt ttgaacgtct
     6601 gagaactttc gccatttttc catccttcat ttcagcaatc agtgaaccat tggaagaaat
     6661 caaatagcca ccgattccta attcggaaaa aatatcttta gcagaaatgc tgttccttcc
     6721 ggtagcgacg gttacgattc cgccattttc atcaaatttc cgaagtgctt ggatattttc
     6781 ttctggtatc tttccatttc gatcaagcaa ggtaccgtct aaatcaatcg ctgctagttt
     6841 cattttatct tcctactttc tttttacata tctattttcc tgttacctta agattaaatg
     6901 agaatttaaa aaaatgaaac taacttgctt tgtcattatg aattttttca aaaaacattc
     6961 ttaagaaaaa ggtggctata tatagtagtt tttggtcaat acctttgaat aaaaagccat
     7021 gaaaaacgaa tagttagcgc ttaccgatgc gttttgtgat aaaaaaattt taaaatattc
     7081 aatgaaaaca aagcatatat tttgctttaa aaccaaatga ggaatattct agatgtagaa
     7141 caggttagaa aaagattaga aaaaggagtg attttgatgg agaagagata cggcgtagtt
     7201 cctgtggtaa ctgcttcaga cgaaaattat gctccttact tgagcgtgat gatcgcaact
     7261 gcattagaaa attgcaataa aacaagacgc ataaaatttt atgtgattga cgatggtcta
     7321 tcagaatata gtaaagaagg attggaagaa acggtaaata aatattcaag taatgcaagt
     7381 atccaattcc tgacagtgga aaaagatatc tacgaagact tcctagtcag tgaccatatc
     7441 acaactaccg cttacttaag aatttcttta ccaaacttat tagctaaaga ggattataag
     7501 aaagtccttt acttagattc agatgtgtta gtactagacg atatcgtaaa actatatgat
     7561 gagccgttaa atggaaaaac aatcggcgct attatcgatc caggccaagt gaaagctttg
     7621 gaaagattag gaatcgattc cgatgacttg tacttcaatt caggagtgat ggtgattgac
     7681 attgatcaat ggaataaaaa agaaattaca gaaaaaacta tccattacct cagtgaaaat
     7741 ggcgatcgaa tcatctatca cgaccaagat gctttgaatg ctgtacttta tgaagattgg
     7801 gaacaacttc atccaaaatg gaacatgcag acttcgctga tttttgaacg tcatccagca
     7861 ccaaatgaaa aatatgaacg tcagtataaa gaaggaaatg aaaaaccttc gatcgttcac
     7921 tttacaggac atgataaacc ttggaatacg ttgaaagatc atccgtatac caatttatac
     7981 ttaaaaaaat tagcacacag tactctaacg aaagtaggcg agatcaatga ataaaaaaga
     8041 aatagcagta gtcgcaagtt gtaacacaaa attcgtacca catttagctg cattatttgt
     8101 ctcagtatta gataattgca acccgtctaa atttgttcgg ttctatgtga ttgacgatga
     8161 tatcgatttt gaaagtaaac agcttttacg cttctcagtg aaaaacgcac gaatgaactc
     8221 agatgtggaa ttcttgaaaa tcaataaaga attctttaca aatgtggtaa tcagcgatcg
     8281 tattccagaa acagcttatt atcgtattgc gattccggaa ttgttccgcg gcacagaagt
     8341 tgaacgtatc ttatatatgg attgcgacat gatcgcttta caagatatct ctaaattatg
     8401 gcgtcttgac ttcggtgatt caatcgtagc agctgttgaa gacgctgggt tccatcaacg
     8461 actggaaaaa atgaaaattt cagctaaatc aatgcgttat ttcaactcag gtttgatgct
     8521 gatcaatgtg aaaaaatggt tagatgaaaa tattacgcaa aaagtattag atttcatcga
     8581 acataatcca gaaaaattac gattccatga ccaagatgca ttaaatgcta tcttacatga
     8641 ccgttggtta ccacttcatc cgcgttggaa tgcacaaggc tatatcatgg caaaagcaaa
     8701 aaaacatcca acagcagcag gtgaacgtga atacgaagaa actcgcaaca atccttacat
     8761 tatccatttt tcaggacatg tgaaaccgtg gagcaaggat tttgaagggc caacgaagaa
     8821 atattacgaa aaatatgcag ggatgacggc tttccgttgt gtagctaaat tccctaaata
     8881 tccaaaatat gcaaaagttc aaccaaaaac agatgtagtt gttaaataat agaagacaac
     8941 aactgaagag ggggagtagg aatggaaatt acaatgtcta aaaatgcagt agagacgtta
     9001 attgaaaagg ttggggaaaa tacaaaaatc gcactcgcgc ttatcaatga ttccgatcca
     9061 tttctaaggg acaaaggtgc ttttgcaaaa ggcagctttt ttcaaatcat tccttttgtt
     9121 tcggaatttg gagaatatgc gactaaaatc gagcatccat tattggacat ctatacatct
     9181 aaattagagc aaaattattt cggtaaacga ttgaacatgg acttcaacaa acagcttgac
     9241 agcttttcat tagaaaatga aatcgcagta ctcgattata atatcaaatt aaagaactgc
     9301 ttcttcagct aatagtttcg agaaagtcca aaaaggaggt atacattgag atactacttt
     9361 gtggatgaag aaaagaatgt aatagaaaca gatgaaaaaa aatataattg gctcgtactt
     9421 gatagtgcaa agcccgaaga gattgagcaa gcaatcgaag aattcgagct tcctgatgat
     9481 attttcgtag gaaccgaata tccggaagaa gtttctcgga tggagcgcct ttatgagacg
     9541 aaactagagc atccattttc tttggtagtg attaatctag atcagtcaga taatcgtatc
     9601 gaaaaaaaat taacgccaat atcttttgta ctttccgata atctcttgat tacttgtatc
     9661 gatagaaaaa ccgaatttgt ggatcggctg ctgacaaagc atggaaatca tttaaactcg
     9721 tttgaaaaga tcatcacgta tacattatta gatatttaca cccattacgt gaaagaacta
     9781 agagagatga aaaagcgaat tgacgctttg gataaagcag ctcgtaaaac aacggaaaat
     9841 gaagaactgt ataaacaggc agatcttgaa agagacatcg tatatatcga tcatacctta
     9901 agagatcaac gggaaacaat ggatcaatta tggaattctg aaactttcat caaacgttta
     9961 gacgatgaac agctactcta tgatgtccat ttgagacagc gacaaacaga aaaaatgatc
    10021 gagatctatc gagatttatt agagagtatt ggtgatctat tcaacgggat gatggacaat
    10081 aatctaaatc atatcatgaa atatctagat tcagctgcat taatcatttc cgttccggcg
    10141 ttgttcgcag ggatttgggg aatgaataca ggaggattac cgggtaaaag ttctgctcta
    10201 ggctttatac tcgtagtctt tggctctttg atagcagcag tagttttagg ttaccattta
    10261 taccggaaag attatacaaa ttaaagaatc tatttaaaac aggtatcaaa caaagaaatt
    10321 tgttttggca atacaattta aaaactagga ggaatacagc aatgacagaa ccaaaattaa
    10381 tcgacccgcg aaacttgtac catacggaga aatttcctaa acaagatcag gatacaccag
    10441 ctttacagca gaatatgatt cctgttcctg attgtggaga agaatcctat gaaggcaata
    10501 atcaactaga aaaccgccgt gtactaatca ctggtggaga ttcagggatc ggtcgtgcag
    10561 cagcgattgc atttgctaga gaaggggcag atatcgctct tcaattcttc ccaggagaag
    10621 aaaaagatgc agaggaagta gcaaaatacg tgaaagttgc aggacgtaag attgtcttac
    10681 taccttttga tcttcgtgac gaacaagcac ctaaagaaat catagataaa gccgtgagtg
    10741 aacttggcgg gctagatacg atggtactaa acgcaggaca gcaaatttct tgtcagtcta
    10801 ttgctgagtt accacttgag caagtcaaag acacatttat gataaacatc atcgctatgt
    10861 ttgctttagt gaaagaagct gttccgcata tcccagcagg aggagcaatc gtaacaacaa
    10921 cttctgttca agcattcaat ccaagcgaac atttattaga ttacgcagca acaaaagctt
    10981 caatcgctaa ctttacgatc ggtttagcaa aacagcttgc acctaaagga atccgtgtaa
    11041 atggtgtagc acctggtcca atctggacac cattacaact agacgaagga caaccttctg
    11101 attcgatccc tgaatttggt cagcaaagtt tactagaacg tgcaggtcag ccaggagaat
    11161 tagcaccagt ttatgttttc ttagcatcga ataaagcaag ttatgttaca gcccaaattt
    11221 acggagtaac tggtggagaa gcgatcaact tataagaagt tgatcgtttc acccctatga
    11281 ggaggtgcga aaatgaataa aggtgtaaaa acgatcggag tgatcggaac attacttttg
    11341 ctatctgtgc ttttgtttgc gatactatta agtgcaacct atccattgcc ttttcagcta
    11401 gagaagtttc gattcttttc catcactaat tcatacgtgc aacaatatgt attttggctt
    11461 gccgttgcat ttgctatttt gacaattatc acgttacttg ttttcctgtt ttatccaaaa
    11521 acaatcggaa actttctact gaaacatggt gatggggagt tgacgttgga taaaaaagca
    11581 attgaaggaa tggttcgttc tcacttgcat gaagatgaat tcatccattc accaaaagta
    11641 aatgtcaaag caacgaaaaa caagatcgcc gtcaatgtaa aaggggagtt gaaacgaact
    11701 tcagcactca ttggtaaaac aggaacattg atgaaagaaa tcgaaaatga agtacaacac
    11761 atattgggaa caaaagagcc agtgaaagta tcggtgaaat acacaggctt tgaagaacca
    11821 gctaaacgaa gcaatgaccg caaacgagta gaataggggg ggaccaaaaa tgaaagaact
    11881 attttcgaca tacaagctcc ctatcatctt tggggtactt ggattgatat tagccgtttt
    11941 atggatcacc gtgggctttt tcaagacctt attgatcttg atcatggcag cgatcggcgt
    12001 cgctatcggt ttttatctga aacaaacgaa aatcttagat cactatttta aatcttagga
    12061 ggaaacatcc atgaataaca ataacaaaaa taataacaat aaaatgaaca accaaaaacc
    12121 agtgtctgca catccagacc caacgacacc aaaccaatca aatggtgtga acgatgaaaa
    12181 gaacaaaaca gcaccagtat ctgcacatcc agatccagta gtccctaacg ttcaacaagg
    12241 agtagaagag aagaaacatg atgcagaaaa gcatgcacct catcatccag gaactccaga
    12301 atctaaagtt ccagaacaac atgatgcaat cgatccttct aaacctgtgg aagagcaaaa
    12361 acatccttct gaccatgcga aagcacaaga aaaacttagt tctgaccaca caaacggaca
    12421 aggaaaactt ggttctgatc atacaaataa ccaaggaaag catgattctg aacaggaaga
    12481 ttcaatgcgc ggtgagctga attatgaaga taaagttgtg caaaaaatca tcggaatcgc
    12541 aattgaacaa gtagacggtt tattatctgc aaacggtggt ttcttctcta atgtggcagg
    12601 aaaacttgtg aatacagata atgtaacggc tgggatcgaa acagaagtcg gtaaaaaaca
    12661 agtagcagtt gatatggatg tcattgtgga atatggcaaa gatatcgaaa aaatctttga
    12721 agaaatgcaa gaagtaatcg gcaaagaagt aaaaaatatg acacatttag aagtgatcga
    12781 agtcaacgct aacgtagtgg acatcaaaac aaaagaagaa tttgaaaaag atcaagaaac
    12841 ggtgcaagac aaagtaactg acgcagcgaa aaaaaccggt gaatttgctt cgaatcaaac
    12901 agataaagta aaatcagcag ctggaagcgg cgcacaaaaa gtaaaagaaa atacagaacc
    12961 acgggttcag taataaggaa gtaaaacatt aggaggaacg aaacatggga tttatttggt
    13021 cacttatcgt cggaggaatt atcggagcaa ttgcaggagc aatcacgaat aaaggttctt
    13081 cgatggggat tattgcaaat gtcgtagcag gtttagttgg atcagcactt ggtcaagcat
    13141 tattaggttc ttggggacca agtattgcag gaatggcaat cgtgccatca ttgattggtg
    13201 ccatcatttt agtactaatc gtatcattct ttgctcgaaa actgtaaaaa gacttttaaa
    13261 aagaggtcgt gaaaaagctg ttcttcatca agtaataaga acagccaaac aaaaatagct
    13321 tctcatattt ttcatttggt tgggcatatt atcgaagatg caagcttttg aacactgttt
    13381 atacggaata agaggctgtg acaagacttt tgtcacagcc tcttatttat gcgggcaaat
    13441 tcccaattag atttttaaaa gtttttcctt aaatgtgtct ttattgatac agagaagctt
    13501 ctttaataaa acaatgcctc cctaaatttt cttgagatag gaaaggtgaa catacaaaat
    13561 aatacgacca ctttgaaaac ccagatgatc cacaaatgga tcgtatgata ctgatgaagt
    13621 aaaaagcaat ggatcagaaa ctcaaagaga ttgaaaaaga caaggaagaa ataatatctc
    13681 ttttttactc ttgtctgttt tagccaataa tagctcgtaa agtaatctag acaaacaaat
    13741 agaagtaaac aaagtttcgt aagagcagca atcgtatcat gttgctctgc tagacgattg
    13801 acgagcagga aaaatgttgg taatggaata tagatcacga gtaatgaaag aaaaaagtaa
    13861 acaataaatg gcatactatt cctcctaatt gtgtgagttc gccctcattt taaaataacg
    13921 atatttgttt gtgaagcttt ttcgtgtcgt aacaaatgtt atctaatgta tttttaaata
    13981 aataatcatt attatcaaaa taat
//
LOCUS       DAPBCF010000062        13979 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.063, whole genome shotgun sequence.
ACCESSION   DAPBCF010000062 DAPBCF010000000
VERSION     DAPBCF010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.063"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(141..1085)
                     /locus_tag="RD508_002353"
     CDS             complement(141..1085)
                     /locus_tag="RD508_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDT7736889.1"
                     /translation="MDTILITGGAGFIGSTLANYLGKENKIVVVDDLSMGKKENLDMD
                     KQVTFIEGDVSDSQLMERIMKEYQFAYIFHLAAVASVADSVERPVETHRVNFDSALLL
                     LELARKYQSNLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKAEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILSGMERYLKTEI"
     gene            complement(1219..2610)
                     /locus_tag="RD508_002354"
     CDS             complement(1219..2610)
                     /locus_tag="RD508_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HDT7736890.1"
                     /translation="MLNERFLKYVKGWYFIYFGFILMLRAIGPYLLLPTRYDTLLFWP
                     AGIAGVVLIIIDAIIAFREKNLKKYDWLLIAFIGAMLVSSLMNLKYGYSENIKLIMWQ
                     LIFFFMIYQFGKDYSSNFFFKVFTWILSLVWFLANLVSLYWFVIQYGIKIPIKYKYYP
                     VRLGWLGNRLFGVYTDPNFGAVISLIVIIIAIYYLVTYKHLNLLFKIFFVINIFIQFS
                     FIALSGSRTTLVCLLITTFVFSFFTSYSSRFLKTNTLKRWLTALVVGLLSIIAMYYVT
                     DITAHAWAHVPHITEVKKDTSDSSGTTSSNKVDLKRPDTDSGDVSNLRFELWKSAIEI
                     FKSKPISGGSPGYYIEYAHDKLPYTLMGKDTLTAHNFIFLVMAATGGLGLLTLLTFLF
                     IQCFKALRYCFTQPNLVKDKHFFAILMILTIAVSALFITELILVSTIGSFIFWGYLGS
                     IQKTISKEEGVTN"
     gene            2736..3146
                     /gene="tagD"
                     /locus_tag="RD508_002355"
     CDS             2736..3146
                     /gene="tagD"
                     /locus_tag="RD508_002355"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HDT7736891.1"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQYGDYLIVALSTDEFNWNA
                     KQKKCYFSYEKRKQLLEAIRYVDLVIPEENWEQKVKDIKEYHADYFVMGDDWAGHFDE
                     LEQLTDAQVIYLPRTPEISTTQIKNELNSLNSDK"
     gene            3322..3735
                     /locus_tag="RD508_002356"
     CDS             3322..3735
                     /locus_tag="RD508_002356"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7736892.1"
                     /translation="MISISHSIKELFTIKDKNIEINSFQETFYKDKKAIVIEGPLVRT
                     FRHCLFCKESAKQIEKNGKKISMIILNRSGNKQTYLRLRKQHYHCQSCGKYFTAHTYL
                     VAPSCFISKQVHYTILEELTERQALKTIAKRCDFQ"
     gene            3892..4149
                     /locus_tag="RD508_002357"
     CDS             3892..4149
                     /locus_tag="RD508_002357"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7736893.1"
                     /translation="MTFCPAGEKKDLIAYFMRFTRKAHMGVRYIVTDMNAPYFSLVKE
                     PFPNAQIIIDCFHIGQHLNKFFDRVRKRVMKQLNQKCQRHL"
     gene            4236..5474
                     /gene="istA"
                     /locus_tag="RD508_002358"
     CDS             4236..5474
                     /gene="istA"
                     /locus_tag="RD508_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HDT7736894.1"
                     /translation="MRKDIREGVMIYVINEIKPNYAALAKQYDCDYRTVKHAYEEAQV
                     KESKPPERKKRPSKLDPYREIIQDKIKDQCSAYSIFKFIEHKGFGGSYSLVKTYCRQI
                     KQAKVHKATVRVEHSPGLSAQVDWKEDMRLISNQGEIFEFNIFLYVLPYSKKKYVTLT
                     FDRKQDTLFECLDDAFYQTGGVPKEIWFDNMKTVVDHSRSQFSKPHFNKRFYAFSKDA
                     GFTPIACRPFRPQTKGCVEALARTVDRLRVYNHEFYDAVELCHLVNNLCVELNNEVSQ
                     STDQTPDERWQTNEKEHLHPYQKNLLNPYFEDFIRRKVTKEEMVIFRKCRYSVAPRYI
                     GKEVEIELSDKEDQVQIYYNGELIRSHPLTTKQLNYHEEDYFQILKSDVMSHKEDDGI
                     RAYTRESLKQYDLVEVADEE"
     gene            5464..6204
                     /gene="istB"
                     /locus_tag="RD508_002359"
     CDS             5464..6204
                     /gene="istB"
                     /locus_tag="RD508_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HDT7736895.1"
                     /translation="MKNSHYQELMTNLETLGLNHMREYVPNYIEVANREELSLTEALL
                     ELTRREVDHQNKQKMNRVVARARFSKRTSLEEFDFAFQPSINKREVLDLRHMGFVEKH
                     ENLVFIGSPGVGKTHLTIALGIEACRQGYRTLFITCHELLLRLRTAYEKGTLERVLKR
                     YARYDVLIIDEIGYLPIQKQEADLFFQLLAMRYEHRSTIITTNIVLSRWGELFQSSEI
                     AAAILDRLVHHVKVFKITGKSYRMRDKI"
     gene            6614..6778
                     /locus_tag="RD508_002360"
                     /pseudo
     CDS             6614..6778
                     /locus_tag="RD508_002360"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6845..8272)
                     /locus_tag="RD508_002361"
     CDS             complement(6845..8272)
                     /locus_tag="RD508_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HDT7736896.1"
                     /translation="MKKTVKDIFYNAIYQVFLIVLPLLTIPILSRRIGSTGLGIYGYV
                     FSISQFLMTVIAVGMNPFRIRNIAKSRKDKKALSLQFWNIYFLQFLIGLSVSFLYIAY
                     IYFFDVKYKNLYLIQLIFIAGLTLDISWFFQGIEEFSKVVIRNTVIKLSSVLLIILFV
                     STKDDLWIYVFITSITNFLGSLVFWLSIHGKVGKPLFNSNVFKQLWKPAFIILTPQLF
                     MQVYTTLDKTIVGYFVDPTALSYYDQSQKIARIILAVLTSITIVMLPKISKAQAEGKS
                     ENILVYTKKSFDYTIIIALILFSVVFINTKEFVPWFFGENFKPMTINMLISCLIIVVS
                     PIGGVFANQFAIAIEKDKEYAYPMIIGAIVSIIGNVAFVPTYGAVAATIVLVVVELLV
                     FFFRVFFVRKEIKISYFFGKNVVLFFIVNLTLTTSAYYFLPQLFSSSFLDMAIKSIMI
                     FIIYLPFVYFLFPDIRNEVRKIIRK"
     gene            complement(8269..9411)
                     /locus_tag="RD508_002362"
     CDS             complement(8269..9411)
                     /locus_tag="RD508_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDT7736897.1"
                     /translation="MKNIKKFFSRNIFPVFIKILPIQKNLIVFSSFGGRNYSGNPRVI
                     SEKIHEKKLNYRIIWLIKKEAIITDLPDYIKRIDSDSFLAAFYLYTAKYWIDDSRKTI
                     KYAKRKKQFYFQTWHGTPLKKIEFDAKDKLPKRYLSYAKKDSESITYLLSGNRYSSEK
                     YVSAFNIVPSKILEVGTPRNDELASSKEQVFDLKKKQINVLFAPTFRNNIEDNGITQL
                     EWLGVDNLREFFKKQQQELNLMTKFHPNVHSKLATDSKSIEYMKKHQITLINDGIPLE
                     MLFEEIDVLITDYSSIFFDFALTKKPIILFNYDEKEYSLERGFYIQLSELPIISVQDS
                     YGLVDVFKNQQEKLLKSSQELLDYIGNYETGASTEKVLELLERDIK"
     gene            complement(9415..10410)
                     /locus_tag="RD508_002363"
     CDS             complement(9415..10410)
                     /locus_tag="RD508_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7736898.1"
                     /translation="MHKISVIVPAYNVENYLENCLESISNQTHSNIEIIVVDDGSPDR
                     SGEIAEEYKKKDMRLKVIHQVNGGLSAARNSGLDSATGDFVCFIDSDDWIEPDYLELL
                     YFGTQTYGADISVLKIKKISSLEQLKEHTIAERKWEIFDREQAMKNLFINNKIGYSAN
                     NKLFNRNLFDNIRFPLGKLMEDKATTYLLIDHSEKVAVNSSAKYHYYQSPKSILRGSF
                     NPRIFDSFEVHEDILVFIDKFYPELSINVRTRYVYEAIRMMMTMIKNNYTNKEDYLRS
                     INILQRFEKEVKIDPDFSPKLKKLVKFLLINKNLPYYMSSSKIASKFLIKIESVR"
     gene            complement(10524..11513)
                     /locus_tag="RD508_002364"
     CDS             complement(10524..11513)
                     /locus_tag="RD508_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7736899.1"
                     /translation="MNQNLEKQTKLSIIIPFYNAKNTLRRAVDSVLTQGYPNIEILLI
                     DDGSTDGSSDIGDEIANLESKVACYHLENAGPSVARNYGIKEATGNLVGFLDSDDYFL
                     PDCFNNVLKDYHRNHPDIIAFGLSKGKNIENANLFVPEKKIGCSSEEAIEQMFRSKAV
                     DFYVWNKFFKRELFNHIVFPENKLYEDMVPMYEAFRAASKIDILPFSGIFYYQNNDSI
                     VYQSFNSKQYDNILQRKILVDEVKKDYPRLINLANARLVDGYLSTGFKITGKNQNQKE
                     KQKYYNQSKREIKSIYSKIRSNNEISIAKKLALFLYLINPKTYFILYKKVLKK"
     gene            complement(11485..12315)
                     /locus_tag="RD508_002365"
     CDS             complement(11485..12315)
                     /locus_tag="RD508_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7736900.1"
                     /translation="MENKNISILLSLYDKEKPEYLKEALASIFEQTVMPAEIVLVYDG
                     PINEKLQAVVTYFQQKVPHLFTVVKLEKNQGLGIALATGLEHTKNRLVARMDTDDIME
                     PHRLEKQLEIFQEYPEIAIVGSNIEEFTGTLSNVIGRRIVPEYNDEIRVFSKRRNPFN
                     HMTVMFDKNAILEVGNYRPLIGFEDYYLWVRLLKAGYKGYNIQEILVHARAGADMYAR
                     RGGSKYLLPGIKGRYRVWKDGLGSLKDFLIVICGHLVISLLPNKIRGKVYESKLRKTN
                     "
     gene            complement(12353..13744)
                     /locus_tag="RD508_002366"
     CDS             complement(12353..13744)
                     /locus_tag="RD508_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDT7736901.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENISS
                     LAESAFPKEKTYR"
BASE COUNT         4731 a         2537 c         2073 g         4638 t
ORIGIN      
        1 agttctcttt ttcatgtaaa atatttaatt atatatttcc taaataaaaa gtaaaacaag
       61 aattaaatag ttggttatac aactttaatt cttgttttac tttttagaat tatttatcca
      121 aagatgcaat cattttttca tcaaatttct gtctttaaat accgttccat tccgctcaat
      181 atatcaaatt taggctgata gcctaaagaa cgaatttttg aaatatccgc taaggaatca
      241 cgaatatccc ctgaacgctc cgcttcatat ttaagcgcta gctctgttcc taagatttga
      301 tcaattgaat ggatcaattc aagtagcgta gtgctttttc ctgtaccgac attgaattgc
      361 tgtcctaaag ctttttcttc cttggcaaca agtaaaagtg cttgtataac atcttctata
      421 taaacaaagt ctctagactg actcccatcg ccaaataaag taaattccgc tttttctcct
      481 gccaattgtt ttttgtaacg atccactaga atcgaaatga ctccgctata tggagagttt
      541 ggattttgat ttggaccata aacgttaaaa aatcggacag cactagtcgg aacatcatat
      601 aaatgacagt aatccaaaac atattgttct gctgcaaatt tatcgatagc atatggtgtt
      661 aatggacgga tgactgattc ttcttttttt ggcagtgttg gttcatcacc ataaactgca
      721 gctgatgaac taaatactaa tcgttttaaa ttagattgat atttccgtgc taactcaagc
      781 aataaaagcg cactgtcaaa atttacacga tgtgtttcta caggccgttc tacagaatct
      841 gccacactag ctacagcagc tagatgaaaa atataggcaa actgatattc tttcatgatt
      901 ctttccatca attgagaatc tgatacatcc ccctcaatga aagtcacttg tttatccata
      961 tccaagtttt ctttttttcc cattgataaa tcgtcaacta ctacgatttt gttttctttt
     1021 cccaaataat tcgctagcgt tgaaccgata aaaccagctc cgccagtaat caatatagtg
     1081 tccatcaaat tcactccaat tgcacatttt cgtatcaaat aatattagtt taccattttt
     1141 atattgtaaa aactataaaa tttgttgaag ttgggataac tagttttctt ttctactttc
     1201 atatacctaa aaatagtttc aattagttac tccttcttct ttagatatag ttttttggat
     1261 agaacccaga tatccccaaa aaataaatga acctatcgta ctaaccaaaa tgagttctgt
     1321 gataaataat gccgaaactg ctattgtaag aatcattaaa atagcaaaaa agtgcttatc
     1381 ttttactaga tttggttgtg tgaaacaata acgcaaggct ttaaagcatt ggataaataa
     1441 gaaggttaac aatgtcaata gacctaatcc tcctgtagca gccatcacta agaaaataaa
     1501 attatgagca gttaaagtat cttttcccat taatgtatat ggtagtttat catgtgcata
     1561 ttcaatatag tagcctggag aacctccgga tatcggctta ctcttgaata tttcaattgc
     1621 acttttccaa agttcaaacc ttaaattaga aacatccccg ctatcagtgt cagggcgttt
     1681 taaatcaact ttattgctgc tagttgttcc tgatgaatca gatgtatctt tttttacttc
     1741 tgtaatatgc ggaacatgtg cccatgcatg agcagttata tctgttacat aatacatcgc
     1801 aattatactt agcaatccta ctactaatgc agttagccat ctttttaaag tattagtttt
     1861 aagaaaacga ctactataac ttgtaaagaa actaaaaaca aaagttgtta ttaataaaca
     1921 aactaatgtg gtgcgtgaac ccgataaagc aataaacgag aattgaataa aaatattaat
     1981 tacaaaaaat attttaaata gaagatttaa atgcttgtaa gtgaccaaat aatatatagc
     2041 aataatgatg acgattaatg atataaccgc accaaaattt ggatctgtat atacaccaaa
     2101 taaacggttg cctaaccacc ctaaacgaac tgggtaatac ttatatttta ttggaatttt
     2161 tatgccatat tgaatgacaa accagtataa tgatactaaa ttagctaaaa accataccaa
     2221 tgaaagtatc caggtaaata ctttgaaaaa aaagttacta ctatagtctt tgccaaactg
     2281 ataaatcata aagaaaaaga ttaattgcca catgattaac ttaatatttt cgctatatcc
     2341 atattttaaa ttcattaaac tgcttactag catcgcgcca ataaaagcaa ttaatagcca
     2401 atcatatttt tttagatttt tttctctaaa tgcaataatt gcatctataa tgatcaagac
     2461 aactcccgct attccagcag gccaaaaaag taaagtatca tatctagtag gtaatagtaa
     2521 atacgggcct attgctcgta acattaaaat aaaaccaaaa taaataaaat accaaccttt
     2581 cacatatttt aaaaatcttt cattcaacat ttttcctcca tccacctatt tctcataaat
     2641 atttcttatc ctttttagga taaactggtc ctttcaattc taacaaaaaa atgctaaact
     2701 aacaatgtat attaatgaat ttcgagaggt gaaagatgaa aagagtaatt acttacggta
     2761 cctttgattt gcttcattac gggcatatca atttactgaa acgagcaaaa caatacggag
     2821 actatcttat tgttgccctt tctacagatg aattcaattg gaatgcgaaa caaaaaaaat
     2881 gttattttag ttatgaaaaa agaaaacagt tacttgaagc tattcgctac gttgatttag
     2941 ttattcctga agaaaattgg gaacaaaaag taaaagatat aaaagaatac catgcagatt
     3001 atttcgtgat gggcgatgat tgggctggac attttgatga acttgaacaa ctaacagatg
     3061 cacaagtgat ttatttacca agaacacctg agatctctac aactcaaata aagaacgaac
     3121 ttaattcttt aaatagtgat aaataatatt ttttaaacaa taaaagaaca atatatctgg
     3181 ataagacgta aaaaaatggc tctataattt ctaggactga tagaattttc tgtcggtcct
     3241 agattttttg taaaaaaaaa cagacataaa aaaattccga tagaatagag tcgtctaaaa
     3301 catcaatctg aaaggaagtt tttgatatcc atttctcatt ctatcaaaga gctcttcact
     3361 attaaagata aaaatattga aattaattct tttcaagaaa ctttttataa ggacaagaaa
     3421 gccatcgtaa tcgaaggtcc attagttcgc acttttagac attgtctatt ttgtaaagaa
     3481 tctgcaaagc agatcgagaa aaacggcaag aagatttcaa tgattatctt aaatcgcagt
     3541 gggaataaac aaacctattt gcgtcttaga aaacaacatt accactgcca atcatgcggg
     3601 aaatatttta ctgctcatac gtatcttgtc gctccttcat gttttatttc gaaacaagtt
     3661 cattacacga tattagaaga gttgaccgag cgtcaagcat taaagacaat tgcgaaacgt
     3721 tgtgattttc agtaacgaca gttcaacgga cattatctgc tctatcggca acgctgcgac
     3781 agaagctaga ctatttacct cattgtttac tattcgacga gtttcgctct ctttcaattt
     3841 tccatgggaa gttctccttt tcttgtatga attgagagac agggaagctc tttgacattt
     3901 tgtccagccg gagaaaaaaa agatttgatt gcttatttca tgcgttttac aagaaaagct
     3961 catatggggg ttcgatacat tgtcacagat atgaatgccc cttatttttc attagtcaaa
     4021 gaacccttcc caaatgcaca aatcatcatt gattgctttc acattgggca acacttgaac
     4081 aagtttttcg atcgtgttcg aaaacgtgtg atgaagcagt tgaatcaaaa atgtcaacgg
     4141 cacctttaaa atgtaggaaa acggcaattt aaaattgttg gtttacctac atttttgtat
     4201 gctcttctta tcccaaatga aatggaggct cagggatgag aaaagacata cgcgaaggag
     4261 tgatgatcta cgtgatcaat gaaatcaaac ccaattatgc tgcactagca aaacaatacg
     4321 actgcgacta ccgaacagtt aagcatgctt acgaagaagc ccaagttaaa gaatcaaaac
     4381 ctccagaacg taagaagcgt ccaagtaagt tagatcccta cagagaaatc atccaagaca
     4441 aaatcaaaga ccaatgcagt gcttacagca ttttcaagtt tattgagcac aaaggatttg
     4501 gaggaagcta cagtttagta aagacctatt gtcgccagat taagcaggcg aaagtacaca
     4561 aggcaaccgt ccgagtcgaa catagccctg ggctttctgc tcaggttgac tggaaggaag
     4621 atatgcgact aatcagtaat cagggcgaaa tttttgagtt caatatcttt ttgtacgtct
     4681 tgccatattc caagaaaaaa tatgtcacac taactttcga ccgaaaacaa gacacactct
     4741 ttgagtgctt agatgatgcg ttttatcaaa ccggtggcgt tcccaaagaa atctggttcg
     4801 ataatatgaa gacagtcgtt gaccattctc gtagtcagtt ttccaaaccg catttcaaca
     4861 aacgttttta tgctttcagt aaggatgccg gcttcacacc aattgcctgt cggccatttc
     4921 gtccgcaaac aaagggctgt gtcgaagctt tagccagaac tgttgaccgc ctacgggtct
     4981 ataatcatga attttatgat gccgttgagc tgtgtcattt agtgaataac ctttgtgttg
     5041 agttaaataa cgaggtttct caatcaactg atcaaacacc agatgaacgt tggcagacga
     5101 acgaaaaaga gcacctgcat ccataccaaa aaaacctttt gaatccctat tttgaagact
     5161 ttattcgccg taaagtcacc aaggaagaaa tggtcatttt ccgtaaatgc aggtactctg
     5221 tggcgcctcg ctatatcggt aaagaagtcg aaatcgaact ctccgataaa gaagaccaag
     5281 tacaaatcta ttataacgga gaactgattc ggtcgcatcc attaacgaca aaacagctga
     5341 actaccacga ggaagactat ttccaaatct tgaaatccga tgtcatgagt cacaaagaag
     5401 acgatggaat cagagcgtat actcgtgaaa gtctcaagca atatgatctg gtggaggttg
     5461 ccgatgaaga atagccatta ccaagaactg atgaccaact tagagactct tggtttgaat
     5521 catatgcggg aatatgttcc taactacatc gaagtggcca atcgagagga gctttcttta
     5581 acggaagctc ttctcgagct gacacgcaga gaagttgatc atcaaaataa gcaaaaaatg
     5641 aatcgtgtgg tggcacgcgc ccgcttttcc aagagaacca gcctggaaga gtttgatttt
     5701 gccttccagc caagtatcaa taagcgcgaa gtgctagact taaggcacat gggctttgtg
     5761 gaaaaacatg agaacttggt ttttatcggc agtcctggtg taggcaagac acatctgacg
     5821 attgcattgg gaatcgaagc ctgtcgtcaa ggctatcgga cactattcat cacctgtcat
     5881 gagctgcttt tgcgtctgcg aacagcctat gaaaaaggta ccctagagcg tgttctcaaa
     5941 cgatacgctc gctatgacgt cttgattatt gatgagattg gctatcttcc gattcaaaaa
     6001 caggaagctg atttattctt tcagcttctt gccatgcgct atgaacaccg ctctacgatc
     6061 attacgacga acattgtctt atctcgttgg ggggagttgt tccaaagttc tgagatcgca
     6121 gctgccatcc ttgaccgttt agtacatcac gtcaaggtgt tcaagatcac aggcaagtct
     6181 tatcgtatga gagacaagat ctaaagtgtc gattgtcgac aattactatt gccgaaaacc
     6241 tacattttta tcctgcccaa aacctacaat tttaagctgc ccttgacatc aaaaagacac
     6301 ttcacaagct aagtgctatc gacaattgaa acctttgtat aaattacttc tataatcaga
     6361 tgacgagttg gattatacaa cattcaagaa atggcagaat tttcaatggc gctatttaac
     6421 agaaagtgaa gtagttgatt gtctaccctc aatctcttat gaacttaaaa tggcttagca
     6481 gtattatcaa aagctgctta acaattatca caagaaacag ctagctactt cgagaaatga
     6541 ccaaagaagt tccctcgaaa cttcactatc ttaaaaagcc tttttcatat ctgaaaaagg
     6601 cttttaacta gcattttcga aaaagtattt taatacaaaa ttagagaatc ttcgcacaca
     6661 tatcaaaaca ttgaaacgat ttgcttatgg attttgcagt tttaccaata tgcgcttgtg
     6721 gatttttcta atcaacgggt taataagcta tgcattaaaa gctagtaaat cttactaact
     6781 ttgttgatca taaatgacct tatcagcccg atttgacaaa gaactacttt tttacaacat
     6841 tattttattt tcgaataatc tttcttactt catttcgtat atctggaaaa agaaaataaa
     6901 caaacggaag ataaataatg aaaatcatta ttgatttaat tgccatatct aaaaatgaag
     6961 aagagaataa ttgtggaaga aagtaatagg ccgaagtagt caaagtaaga ttgactataa
     7021 aaaataagac aacgttcttc ccaaagaaat aggatatttt tatttctttt cgtacaaaaa
     7081 atactctaaa gaaaaagact aataattcta ctaccacgag tacgattgta gccgctacag
     7141 cgccataagt aggcacaaaa gctacatttc caataatact tacaatcgca ccaatgatca
     7201 ttggataagc atactcctta tctttttcta tagcaattgc aaattggtta gcaaaaactc
     7261 caccaattgg actaacaact ataattagac aagaaataag catgtttatt gtcatcggtt
     7321 tgaaattctc cccaaaaaac catggaacaa attcttttgt attgataaac accacactaa
     7381 aaagaattaa tgcaataata atcgtgtaat caaaagattt ttttgtgtaa actaaaatat
     7441 tttctgattt tccctctgcc tgtgctttag atattttagg caacataaca atagtaattg
     7501 atgttaagac tgccaatata atacgagcaa ttttttgaga ctgatcataa taagataatg
     7561 ctgttggatc cacaaaatac ccaactatcg ttttgtctaa agttgtgtac acttgcataa
     7621 acaactgagg agtcaaaata ataaaagctg gtttccacaa ctgtttaaaa acattagagt
     7681 taaagagtgg tttacctact tttccgtgga tactcaacca gaaaactaaa cttcctaaaa
     7741 agttagtaat tgaagtaatg aacacataaa tccacaaatc atctttagtt gaaacaaaaa
     7801 ggattattaa caataccgat gataatttga taactgtatt tctaataacc actttcgaaa
     7861 attcttcaat tccttgaaaa aaccaagaaa tatctaatgt tagccctgca ataaatatca
     7921 attgaattaa gtataaattt ttatacttta catcaaaaaa ataaatatag gctatataga
     7981 gaaaggaaac actcaagcct attaaaaatt gaagaaagta aatattccag aattgtaaag
     8041 atagtgcttt tttatctttc cttgatttag cgatatttcg aatacgaaaa ggattcattc
     8101 ccacagcaat gacagtcatt aaaaattgtg atattgagaa aacataccca taaatcccta
     8161 aaccagttga acctattcta cgactaagta taggtatagt aagtaagggc aaaacaatca
     8221 aaaagacttg atatatcgca ttataaaata tatcttttac tgtttttttc actttatatc
     8281 cctctctaac aactcaagaa ccttttctgt acttgcccct gtttcataat ttccaatata
     8341 atcaagtaac tcttgagaac ttttcaaaag cttttcttgt tggtttttaa aaacatcaac
     8401 aaggccataa ctatcttgta cgcttataat tggtaactca cttaactgta tataaaaacc
     8461 tctttctaag ctatattctt tttcatcata gttaaaaaga ataattggtt tttttgttag
     8521 cgcaaaatcg aaaaaaatag atgaataatc tgtgattaaa acatctatct cttcaaaaag
     8581 catttcaaga ggaatcccat cattaattaa agtaatttga tgttttttca tatattctat
     8641 acttttagaa tcagttgcta atttactatg aacattagga tgaaatttag tcattaaatt
     8701 taattcttgt tgttgctttt taaaaaattc acgtaagtta tccacaccta accattctag
     8761 ttgcgtaatt ccgttgtcct caatattatt tcgaaaagtt ggagcaaata agacattgat
     8821 ttgtttcttt ttcaagtcaa acacttgctc tttactagag gctaattcat cgtttctagg
     8881 agttcctact tctaatattt tagaaggaac gatattgaat gctgaaacat acttctcaga
     8941 actatagcga ttaccagata ataaatatgt aattgactca ctatcttttt tcgcatagct
     9001 taggtaacgt ttaggtaact tatcttttgc atcaaattca atttttttta aaggcgtacc
     9061 gtgccatgtt tgaaaataaa attgtttttt cctttttgca tacttaatcg ttttccgact
     9121 atcgtctatc caatacttag ctgtatacaa ataaaaggca gctaaaaaag aatcggaatc
     9181 aattctttta atataatctg gtaaatcagt tataatcgct tcttttttga ttaaccaaat
     9241 aattctgtaa ttcaattttt tttcatgaat tttctctgaa ataactcttg gatttccaga
     9301 ataattacgc ccgccaaaac ttgaaaatac aattaaattt ttttgaatag gtaatatttt
     9361 aataaaaacc gggaaaatat tccttgaaaa aaattttttt atattcttca tctcttacct
     9421 cacagattct atcttaatca aaaatttact tgctatctta ctacttgaca tatagtaagg
     9481 caagttttta tttattaata aaaactttac taattttttt aattttggtg aaaagtcggg
     9541 atcaattttc acttcttttt caaagcgttg taaaatattt atagaacgta aataatcttc
     9601 tttattggta tagttatttt taatcattgt catcatcatc cttattgctt catagacata
     9661 gcgagttcta acattaattg ataattccgg ataaaactta tctatgaata ctagtatatc
     9721 ttcatggact tcaaaagaat caaaaattct aggattgaag cttcctctca gtatactttt
     9781 agggctttgg taatagtgat atttagcaga tgaattgaca gcaacttttt cggaatgatc
     9841 gatcaacaaa taagtagtag ccttatcttc cattaattta cccagtggga atcttatatt
     9901 atcaaataaa tttctattga ataatttatt atttgcagaa tagccaattt tattatttat
     9961 aaataagttt ttcattgctt gttctctatc aaatatttcc cattttctct cagcaattgt
    10021 atgttctttt agttgttcta aacttgaaat cttttttatt tttagcaccg agatatctgc
    10081 tccataagtt tgcgtaccaa aatatagtaa ctcaagatag tctggttcta tccaatcatc
    10141 gctgtcaata aagcacacaa aatctcctgt tgcagaatca agaccagaat tcctagccgc
    10201 acttaaacca ccattcactt gatgtatcac ttttaatcgc atatctttct ttttatattc
    10261 ttctgcaatt tccccacttc gatccgggga accatcatcg actactatta tttcaatatt
    10321 tgaatgtgtc tgattggaaa tagattctaa gcagttttct aaatagtttt ctacgttata
    10381 tgcgggtact ataacactaa ttttatgcac tctcttcact tcctaaaaat catctttttt
    10441 atttttacaa atgtatcatt accagtaaca attttagtct tccgaagtta ataaacataa
    10501 aaaataacat atcgaaaaaa actttatttt tttagaactt ttttatataa aataaaataa
    10561 gttttaggat taattaagta taaaaataaa gctaattttt tagcaattga tatctcattg
    10621 ttacttctta tttttgaata tatacttttt atttctcttt tagactgatt ataatatttt
    10681 tgtttttctt tctgattttg atttttgcca gtaattttaa accctgttga aagatatccg
    10741 tctactaacc gagcattggc caaattaata agtcgaggat aatctttctt tacttcatca
    10801 actaatattt ttctctgcaa aatattatca tactgttttg aattaaaaga ctgataaacg
    10861 atgctatcgt tattttgata ataaaaaata cctgaaaatg gcaaaatatc aattttacta
    10921 gccgccctaa aagcttcata cataggaacc atatcctcat ataatttatt ttctggaaaa
    10981 actatatgat tgaataattc ccttttaaaa aatttattcc atacgtaaaa gtccactgcc
    11041 ttacttctaa acatttgctc aattgcttct tcacttgaac aaccaatctt cttttcggga
    11101 acaaataaat ttgcattttc tatatttttt cctttactta atccaaaagc aatgatatcg
    11161 gggtgattcc tatggtagtc tttcaaaaca ttattaaaac aatcaggtaa aaaataatcg
    11221 tcactatcta aaaatcctac caaatttcca gttgcttctt ttatcccata gttcctagca
    11281 actgatggac cagcgttttc caagtgataa catgctactt tactctctag attagcaatt
    11341 tcgtcaccaa tgtcactact accatctgta gatccatcat caattaacaa gatttcaata
    11401 ttgggataac cttgcgttaa gacgctgtct acagctcttc ttaaagtatt ctttgcattg
    11461 taaaaaggta tgattataga aagtttagtt tgtttttcta agttttgatt catatacttt
    11521 tcccctaatt ttattcggta ataaactaat tacaagatgt ccgcaaataa ctatcagaaa
    11581 atcttttagt gatcctagac catctttcca tacgcgatat cggcctttaa ttcctggtaa
    11641 aagatattta cttcctccac gtctagcata catgtcagca cctgctctag catgtactag
    11701 aatctcttgg atattatatc ctttatatcc cgccttcaat agtcttaccc acaaataata
    11761 atcttcaaat ccaattaatg ggcgatagtt tcccacttct aaaatagcat ttttatcaaa
    11821 catgactgtc atatgattaa aagggtttct tcttttcgaa aacacacgga tttcatcatt
    11881 atactcaggt acaatccttc ttccgataac attgctaagt gtgccagtaa attcttcaat
    11941 attactccca acaatcgcta tttctggata ttcttggaag atctctaatt gtttttccaa
    12001 tctgtgtggt tccatgatgt catctgtatc cattctggcc actaagcgat ttttagtatg
    12061 ttctaatcca gttgctaaag caatccccaa tccttgattt ttttctaatt ttacaactgt
    12121 aaacaagtga ggaacttttt gctggaaata agtgacaact gcctgaagct tctcatttat
    12181 agggccatca taaaccaata cgatttctgc cggcatcacc gtttgctcaa agatactagc
    12241 taatgcttcc tttaaatatt ccggcttttc tttatcatac aaagaaagca gtatacttat
    12301 atttttattt tccaatgttc tctcctactt ctttgctcaa aatttttcca atctaacgat
    12361 acgttttttc ttttggaaat gcactttctg ctaatgaact gatattttca tcttcatcta
    12421 gtccttgtga ggacatctta tcaaataaga ttttgattgt ttgaagtaaa atcttcaaat
    12481 ctaatagtaa ggaatacttt ttgatataca acaaatcaaa acgtagttta ctgttataat
    12541 ctgatacata ttttccgtat acttgtgcat atccggtaat tcccgcacgt acattgtgtc
    12601 ttaagtaata ataaggattt tcttcattga actgatcaac gaaaaatggt ctttctggcc
    12661 ttggaccgac aatcgacata tcgcctttca atacattaaa gatttgaggt aattcgtcaa
    12721 aacgtacagc acggataaat ttacctactg gtgtcacacg tgcatcgtta cttttagcca
    12781 agactggtcc tgattttgct tcagctgtcg cactcatgga acggaattta tagattgaaa
    12841 attccttttg atttttcgta atacgtactt gtttatagat gattggtcca ggtgaagttg
    12901 tttttaccaa aatcgctgtg attagcataa aaggtgaggc gaggatcagt aaaataagcg
    12961 aaacgatgat atcaaagaga cgcttgaata gttcgtattc tggttggatt ctgaacccag
    13021 aagcttcaat gatgctttca tcttcaaaat tcataatatt cggatttatc attgtcagat
    13081 tctcaaaagt cgtatttaaa aataatttct tctctttttt agtcactaat tgataaatgt
    13141 tgattttttc atcttctggg attttagaag ccaaatagac gatatccata tcatcgatca
    13201 atttttttgt attttcgtaa taattatcga ttgccactgc ttcaacctta tgtttattgt
    13261 ttttcttaga ttgaaaattt tggatagctg gtgcgacatc tttctccaaa cccacgataa
    13321 ggactttctt atcacgactg actcttaagt acagtttgta aacgactatc cggtaaacac
    13381 taagtaatat cgtacctagg ataaacgaga tcaaaatgac gccacgcgga aatgcaaacc
    13441 atcggccagc aaaagtaact accatgatcc ccaatgctat tagtacttgt ccaataacag
    13501 taatgaagac aatatcactg atcattcggt tatagaatac ataagctcct aacaaaatat
    13561 tcaacgcaat aaagatgatg gaaataaaaa ttgctgaatg ctgaaaggtt tctaagtttc
    13621 tcactggtac ttctccctgg aatttcagca aaaaactaag atagatcgat acatttaata
    13681 caagtacatc cataagaata atgaatattc tgcgtgccgc attccactcc ccatttttat
    13741 tcatatatac actcctaacc ataaaataat gcctctatca tcttaccata gcaaagttta
    13801 aaaacctagt gaataaccaa attgtaaagg aaattaaaag aaacggggaa aagcgtttat
    13861 tgtctgttta tatgtgtatt tctgcataac agaaagttgt ctcagaagtc ccatcacttc
    13921 ctttatgctg aactagtatt ctcctgctaa ttccttattc acaagttaca atattcata
//
LOCUS       DAPBCF010000063        13732 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.064, whole genome shotgun sequence.
ACCESSION   DAPBCF010000063 DAPBCF010000000
VERSION     DAPBCF010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.064"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(63..1268)
                     /locus_tag="RD508_002367"
     CDS             complement(63..1268)
                     /locus_tag="RD508_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDT7736902.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            complement(1291..1444)
                     /locus_tag="RD508_002368"
                     /pseudo
     CDS             complement(1291..1444)
                     /locus_tag="RD508_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(1447..2832)
                     /locus_tag="RD508_002369"
     CDS             complement(1447..2832)
                     /locus_tag="RD508_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDT7736903.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(2861..3247)
                     /locus_tag="RD508_002370"
     CDS             complement(2861..3247)
                     /locus_tag="RD508_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7736904.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(3263..3577)
                     /locus_tag="RD508_002371"
     CDS             complement(3263..3577)
                     /locus_tag="RD508_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7736905.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            complement(3930..4409)
                     /gene="rlmH"
                     /locus_tag="RD508_002372"
     CDS             complement(3930..4409)
                     /gene="rlmH"
                     /locus_tag="RD508_002372"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDT7736906.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            4837..6126
                     /locus_tag="RD508_002373"
     CDS             4837..6126
                     /locus_tag="RD508_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDT7736907.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVMMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(6165..6770)
                     /locus_tag="RD508_002374"
     CDS             complement(6165..6770)
                     /locus_tag="RD508_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HDT7736908.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVASYGMICSARELHLPNAPEKKGILVLPEDAVVGEVFPK"
     gene            complement(6966..7430)
                     /locus_tag="RD508_002375"
     CDS             complement(6966..7430)
                     /locus_tag="RD508_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7736909.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKALEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(7452..7772)
                     /locus_tag="RD508_002376"
     CDS             complement(7452..7772)
                     /locus_tag="RD508_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDT7736910.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VIKG"
     gene            complement(7915..8994)
                     /gene="pepA"
                     /locus_tag="RD508_002377"
     CDS             complement(7915..8994)
                     /gene="pepA"
                     /locus_tag="RD508_002377"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HDT7736911.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            9194..9544
                     /locus_tag="RD508_002378"
     CDS             9194..9544
                     /locus_tag="RD508_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDT7736912.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKTSFLKEGAIEGAWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLDISRKKGAID"
     gene            9729..10682
                     /locus_tag="RD508_002379"
     CDS             9729..10682
                     /locus_tag="RD508_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7736913.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            10695..12482
                     /locus_tag="RD508_002380"
     CDS             10695..12482
                     /locus_tag="RD508_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736914.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            12469..13671
                     /locus_tag="RD508_002381"
     CDS             12469..13671
                     /locus_tag="RD508_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736915.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
BASE COUNT         3938 a         2689 c         2519 g         4586 t
ORIGIN      
        1 aggttttgtc caaaattcat aaaaatgttc tcctctctat attcaatgaa tttgtatttg
       61 agttattttt ttgttgttat cacgtcctgt tcttttactg actgttgctt caaaatctgc
      121 ttgtgtcggt ctgtcagttt cgcatggtcg agaatgtctt ttacaacctg cgtctggttg
      181 atttcatcaa gtttaatcgc aacctttaag gtcggggcaa cttgatgaga tagccagttc
      241 agcgtccttt ggaaggagta aggctctggt tttgtggtta gttttaatcg ttcacgattg
      301 ttcccaataa accaagccca ttcttcattc agtttccaat cagaacgagg tttggaatcg
      361 tctttatcta caaaacggat ataccgattg ataattttaa aggcggtatg ctctggattg
      421 tcatagacga gtaaatcacg gactgcataa taggcacgct catttttcaa tcgaatctca
      481 aaacggtttt ttacttctgc gtcttcaatg ggaatatcat ttttcttgta ctgctcgtag
      541 tccttttcat agatacagaa ataaacttca ctttgtaatg aaccgatata gagggtgttt
      601 cccatacatt ccttttcctc tttgcgtacc agttcgccac tgcgatagct tttaaaactg
      661 cggaagacgg agatacattc ttcctgttgg cacttttcag tgagtacagg gatatttaaa
      721 atccctgtct tatcgttaat ggcaaggtca aggcgtttca tcacaccgcc agccaccaaa
      781 acgtccataa agaactcata ccagcttctt tgttgtgcca gaagatagct ttcaaattgt
      841 ctgcacccac gacctttcaa ttccaccaga actcctttgt ccagttcatg ggagcaaagg
      901 acgaatatgt cgcctaaagc ataatgctct gaataagaat agaaaccata gtcctcatga
      961 agaaaatagg acagtttcag ttgtaagatg ttttcgacca cctgctgtac gtctgttgtc
     1021 ggaaagcgaa ttcttacata atcaaacagc atttcaaggg gagcgtcggg attgaagcgt
     1081 tccagagctt cccaaaggga ctgctgtaaa tcctctgatg gcttgacttt tcctgtttca
     1141 atatcgctta gatactgcct tgtaatacca gtcgcaacag ctaaacggtt ttgagatagt
     1201 ccataagcca agcgtttttc ttttaaatgc tgtaaccaag tttgttcatt cagtaaaaat
     1261 ccctccaatc aaaaaggcgt atgtcaactt ttaaagccca tttgacatac gctgaaattt
     1321 tgtaaatccc ttgtaaccaa aggattttct aatgtttttt tgactgtttc ctgtcgattt
     1381 gtacccccct gttagatacc gaggggttaa gtgctggcgt ggctattgcc acaccagcca
     1441 gcaagatcag tccacacctg cgacttccgc ttcgcacgtc gcctgcgtgg actgtctgct
     1501 gttggataac tttttaattt cctccaagaa atcatatcct tttggtacaa ggggagtata
     1561 aaactctgat atgacacttg ttcctacatc aacatagcca cgacctttga ttcgctttaa
     1621 gaagaaatcc ttttgtacgt cactgccaaa catcatgcca tagcccattt cagacatacg
     1681 acctaaagcc actctgaaat taaactgatc acggattccg tcgcctaaat attttgcgtc
     1741 tggacgttga caagccagta ttagaaagaa gccagcttga cgacctaaca tgacaatctg
     1801 tttcagctta ttcataactg cggtgttttc ttttgttccc agcatttcca tgaaagcgac
     1861 gtattcatca aagattaaga agtgtgccgg gagacctaag taagcataat ttttgccagt
     1921 cttatagttc ttcatctgct tcatttcctc actacgtttc atcatttctt catagaatgt
     1981 ttcaatgcaa gaaagcaagt cttcttttct atagtagaca tttgccatca cagaacctaa
     2041 gtccgcaagg tcagcatttt tcgggtcaag aatatacagt tttgaatctg tatgaagcaa
     2101 ggcttcaatc agtgtcagta taaagtaagt tttaccgcca cctgtaccac cagcaatcaa
     2161 catatgaggg agcttatcat attcccacca tacgtttttc attaagcgaa gtttaccatc
     2221 tttagcttct acttcatcaa tagaaatacg actggctatg gtgtcataga gcaaagtata
     2281 ttccacatag gaatccttta actctttatc cgtcagctca cagtacaagc cactctctaa
     2341 tttcttttcc aagtgtaaga gttggtcttg atattttccc agcgtgattt ccacccgtat
     2401 ctgtatcaag ccatttttaa gtcgataata cattttaggg aagtaggtta tcttttcctt
     2461 tgtacgacca gcactatctt taaagaaacc ctctgttttg acctgttcag attcatacca
     2521 cttgttttca agtatcatct ttgccagttt ttgacggtgg taaagttgtt taaccgtatc
     2581 atagcgaacc cgtttgaata caaacgctac cagcaagcag ataagaattg cgacactgaa
     2641 actgataatt aaatagggaa tgtcaatctt atctgcttgt gataggttaa aatcctgcca
     2701 gttgatctgc tggattgtct tcacatgaaa cagtccgaca accagcagga aaacaggcag
     2761 gagtgacgct atcgtaaaat gaaagactaa atctttacca gatgggcgaa tccttttacc
     2821 acgctgtttc atgcgaaaaa gtctcctttc tacctagcga ctatttgtct tgtgtcggtt
     2881 ctttctttgc ttgtggttga gctttgaatg aactagaatc ctttgtcagc acaatatcgt
     2941 ctgccttgat ataccagtca acatctgctc cttgataggt ggcagtagca acggtgtccg
     3001 caatgggatt gataagttcc acccgtgcgt tataatcaaa ctctttcaaa ggcacgctgg
     3061 caggaatact tacttgaatc atgcgtcctt gtcctttgga ttttaagtca taggtacgtt
     3121 ccttgatttc atctgaaacc gacccgtctt cattttggat tctcacttca cgacgtagag
     3181 cagagaattt caattctcca aaagtcgtgt ctttatctaa tacaatgcca tttgctaatc
     3241 tcatcatttt tcctctcttt ctttattctt ttatcatgtc gtcagcatgt aaaaggtaat
     3301 ttgtaaaacc acgagtgccg attttgtagc cctctgcggt aatacgtgga ttgactaact
     3361 tcacacgttc ctcaaagccg aaatgttttt cgccagcttc agcaggaagc accaccacaa
     3421 tatcatctgc tctttgaaca tcagaataga gattatagct tcttgataag acagttagcc
     3481 gtccgttgat tcttcgctga acgactttat cctcgccagc aaattctaaa ttgccgaatg
     3541 ttttttccat gttgggaatc acaaatttaa gttccatatt tttacctatc ctttcttttt
     3601 tattggctga atgaatgttt gatggtctta aagagtgggg aacgaccttt tgattcttga
     3661 ttttttgttt tcataagttc acttcctttc aaaatcgggt aaaaaaatag acacctcatt
     3721 ttttgaagtg tctacctatt aaatattcaa attttattgg aagtatcttt atatcttcac
     3781 ttttcaagga taaatcgtcg tatcaaagct cattcataag tagtaaatta gtagtaaatt
     3841 gagtggtttt gaccttgata aagtgtgata agtccagttt ttatgcggat aactagattt
     3901 ttatgctatt tttctcttaa aaaatatcat tatttgtggt atggagcccc cgcgttgatc
     3961 cggaaggcac ggtagatttg ctcgacgagg atcaggcgca tcaattgatg tggatacgtc
     4021 attttgccaa aagagatctg agcattgctt cttttcatga cggcttcgct gagtcctaaa
     4081 gaaccgccga taacaaaaac aaggtggctt tttccttgga tacctaattg gtcgatttgt
     4141 ttagcaaaag attcgcttgt gggatttttc ccttcaattg ctaagccata gacgtattct
     4201 tgttctttga ttttcgctaa gatccgttct ccttcttttt cttttacttg tctcatttgc
     4261 gcttcgctta aattctccgg ggctttttcg tcaggaactt cgatcaattc gattttcgca
     4321 taggcattca gccgtttgac atactcattg ataccttgga tcaagtattt ttcttttaat
     4381 tttcctactg aaataatttt gatattcatg ttttctctcc tttgatcttc acgctcactt
     4441 tgtttattat aatcaatttt ttcgtctata tgtttatttt gactattttt gttaaaaaga
     4501 tttccccaac agttatgcac aacatccaca ggtttatcca cagaaaacag cgttgtttta
     4561 ccttatttca tcacattcat taggcaaaca tacgttttat aagaatttat ccactttata
     4621 cacaggctgt ggatatgttt tatcccttat ttttccaatc ctatccgcgt agttttacac
     4681 aatatctgtg gaaaaagaaa atcaaatatt ttcatctgaa aacaatgatt tttcctaaag
     4741 tttttcataa aaagttcaaa gtctcaaagt agactaaagt caacaaataa gactatacta
     4801 acagtagata aatgaatgta attggaggag gaacacatgg atagaaaaaa tgtgacacca
     4861 aagatgaaaa aaaataaaaa taatagcctc tggcgtaagt tgggtctggg gcttgttgga
     4921 gggatcgttg gaggactact gacagctggc attttttatg cagcgatggg cactggcaac
     4981 aatagttcta ctgctacaag cggcaatcaa aattctgccg gtgaaacagt tgtggaaaat
     5041 gtcaaagtca atgtagattc tgatatcacc aaagcggtag ataaagttca agacgctgtc
     5101 gtttctgtta tcaacttaca aagtcaaaac caatcaagcg gttttggcgg attattcggg
     5161 cagcaagaag aaagtagcag ctcagatgat agtaatttgg aagcttatag tgaaggaagc
     5221 ggcgtaatct acaaaaaaga cgggaatact gcttatgtag tcacaaacaa tcacgtagta
     5281 gatggacagc aaggtttgga agtcatgatg aaagacggta cgaaggtaaa agctgaatta
     5341 gttggaacag atgcctattc agatttagcg gtgttgaaga tcaattcaga caaagtcgaa
     5401 acggttgcct cttttgggga ctcaagtgct ttgaaggttg gtgaacctgc gattgcgatt
     5461 ggttccccat taggatctga atatgcgaat tctgtcactt caggaatcat ttcttccttg
     5521 aaccgacaag taacaagtac gaatgaatcg aacgaaacag tcaatatcaa tgcgatccaa
     5581 acagatgcag cgatcaaccc gggaaattct ggtggtcctt tagtgaatat cgaaggacaa
     5641 gttatcggta tcaactcaag taagatcgca agtacttctg aatcgacttc taatgtaagc
     5701 gtagaaggaa tgggatttgc catcccaagt aacgatgtag tgaatatcat caaccaactg
     5761 gaaaaagacg gaaaagtgac acgtccagct ctaggtatca caatggtcga cttatctgcc
     5821 gtttctactc agcaacaaga acaaatcttg aagattcctt catctgtaac taacggtgtc
     5881 atcgtgacaa atgtccaaac agctacaccg gcagaaaaag ctgggttgaa acaatacgac
     5941 gtcattacta agatcgatga caaagaagtt tcttctggtg tagaacttca atctgctttg
     6001 tataagaaaa aagtgggaga ttctgtcaaa atcacttact atgaaggctc gaaagaaaaa
     6061 acaactactg ttgaattgac gatcgatcaa tcggcattaa aacaaaatca aaatagtgaa
     6121 aattaataaa aaagaggttg tgacaaagac ttgtcacaac ctctttattt tggaaatact
     6181 tctccgacta cggcatcctc aggcaatact aagattcctt ttttttctgg agcatttggc
     6241 aaatgcaatt cacgagcaga acaaatcatt ccatagctgg ctacccctcg caaagttcct
     6301 ggccagatca tcattccatc tggcatcatg gctcctggtt ttgcaacgac aactttttgt
     6361 ccagcttcga tatttggtgc accgcaaaca atttgcaata ctgtcccatt gtccacttct
     6421 gtctcagtaa tcgataaatg gtcagagtca ggatgcggga cgcatgtttt tacatacccg
     6481 acaacgatct tcggttcatg atcagcttca agctgttctt cgaatcctgc ttctttaatc
     6541 aatcgattca atttcgctaa ttcttcatct gttaagctta cttggccgtt cccttcaatt
     6601 gttagatgat cggagatatg gaaaaagttc caagcaacaa cttgaccttg ttcatctttg
     6661 atccgagcaa cattccattt acgttcgaca gtgttttctg ttcctttatc gtcggctatg
     6721 ataaccatca aagtgtctcc gacgtgtgct ttgttataag caaaaatcat gttctttcct
     6781 ccattatcct ttgctgagat ttatcttaac aaaaaattgc attcactgca tgagattttt
     6841 ttcatgcttt atttccgaag aagcttcttc tggaacacca tttattcgta acaagggact
     6901 gtgacaagac ttttgtcaca gtccctttac tgtttgatta aaaaggttat acaagttcca
     6961 cttgcttaat tactcggctg ttcttcttcg tcagaaacga tcaagacatc acaaggtgaa
     7021 tgacgtatga cgtagctggc tacacttcct gtcataaagc gttcgactgc atttagtcca
     7081 gactgcccaa ccatgattag atcgattgca tatttttttg gcaatttgac tgccatggat
     7141 tcacgaacag agccgtatgc aataattcct tctatatttg tgtaatcaac agattttcca
     7201 tattctttac attcttcgat catttgcttg gctgtttcag tttgctgatc gactagattt
     7261 tgatcaatag gagcatagcc cataaaatta taaaattgct gatcgattac gtttgctaca
     7321 tatactttcc cattattacg gcgagccact tctaacgctt ttttgaaagc agcaagtgct
     7381 tgttcactac cgtcaatacc tactaaaatg ttcttatatt cttgattcat cttgacccct
     7441 cctaacagat gtcagccttt tattacactt tctaggaacg attcgatttc ctgttttgtt
     7501 ttacgatctt tattcactag acgacctaat tcttttccgt cttggatcac gacaaaactt
     7561 gggataccaa aaatgttcca ttcagcggct acatctatgt acttgtcacg gtctacttca
     7621 ataaattgcc aatcagaaaa gtcattttcg atttcaggca tttgcggttt gataaaacgg
     7681 cagtctccgc accagccggc agtaaagaaa aatacacttt ttccagtttc tacgtagcct
     7741 gctaattctt ctaaactatt tgggataatc attctttttc ctctactttc tgtttatgta
     7801 tttttcaatt aaattataca cctttctttc gaactaacaa acattgatcc tctttttata
     7861 aaaaaaatct gacaaaaggt tgcttttgcc agattttata gtttcactat cgcgttattt
     7921 cccgtatacg atcgtgttca ctgttgattt atctaaacct ttcaatgttt gaatcaacat
     7981 ttctcgtgca gcttcaaaat cgcgaatact gaacatcgtt tgatgcgtat ggatataacg
     8041 tcccactacg ccaatcactg tacttgggat tccttcattt tgtgtatgag cagcacctgc
     8101 atctgtaccg ccttttgaaa caaagtattg ataagggatg ttgtttgttt cagcgatatc
     8161 tagcaagtac tcacgcaaac gaggaagcat gatcaaacct ggatcttgga tacgcatcaa
     8221 tgtaccttct cctaaatgtc cgaatgtgcc atttttcgtc actgtgtcat ctgctgcaga
     8281 gcagtctact gcaaagaaca gatctggctt gaatttattg acagaagctt tagaaccacg
     8341 caagcctact tcttcttgga cattcgcgcc tgcaatcaat gtatgaccta atgtttcatt
     8401 ttgtaacgct tctaaagctt ctaataccat tgtacagcca tagcggttgt cccacgattt
     8461 gctgatgata ttcttcccgt tggctgtttt gatcgtttca gcgtaaggaa cgattgtgtc
     8521 tcctggaaga acaccgtaac tcattgcctc ttctcttgat tcaaacccag catcgaacaa
     8581 aatatctgtt acttctactg atttttgtcc gcttgttcct cgtaataaat gtgggggaac
     8641 ggaagaagaa atacatggat aattcttacc agtagaggtt ttaagtgtaa aacgttgagc
     8701 agaaacaacg taagggttcc atccgcctag aggtacgact ttaaaaagcc cgttttcttg
     8761 gatttgtgtc agcatgaatc cgacttcatc catatgtgct gcgaccatta cacgaggtgc
     8821 atccgcttct tcatggtggc gcagcccaaa aatgccgccc aaaccatcta actgtaactc
     8881 atctaccagc ggttccatat gactttccat ataggcgcga acgtcttgtt caaaaccgct
     8941 tgttccttgt aattctgtta actctttgat tcgttgaaat gttttttctt ccatatgcta
     9001 ttcgtctaaa tttcagacta aactcctctc agacttatat tgatctgcgg ataaaatatg
     9061 attttttctg cagaccgatc gtatttatta tagcttattt tttctggtag cggttattta
     9121 tttcaaagaa aatatgagag tgtggtaaaa taaacacaaa gagtagcaag tgagaagaag
     9181 gaggtatatc cacatgtatg aagaaagcga attaagctat tttaaaggcg ggttagccgt
     9241 tgggatcggt ctaggattat tgagtggggt agcttcaacg atttggtatc atcgcaaaaa
     9301 agtgttatca gcagaccaag tgcttgaaaa tatcaaaaca tcttttttaa aagaaggcgc
     9361 aatcgaaggt gcttggatct cttttgaaaa agaacctatt cggaaattcg ccgttcggtc
     9421 gagtgcttat cggggtgggc tttcccggat agaagatggc gaaactgttt attatgaatt
     9481 tttagcagat gctcatacag gaaccgtatt agacatttca agaaaaaagg gcgcaataga
     9541 ttaatacgtc aaaaaaatga aataacgaat acgcacccac tatctaaaag agaggtatcc
     9601 tatccttctt ttatagtggg tgatttttat aaaaataggg ctatttcctc ttggaatagc
     9661 tagtatttgt agttattata cggtattctt gaaataagat tagttttatt atataaggag
     9721 agtgacaaat ggaatcacgt gaaaaaattg ccgtgctcat tccttgttat aacgaagagg
     9781 cgacaatttc aactgttatt gaagatttta aaagggaatt accagaagca gatatttatg
     9841 tctatgataa taattcgacc gatcgaacat acgaattggc cgttcaaggc ggagcaatcg
     9901 taaagaaaga accacgtcaa ggaaaaggga atgtaatccg tcaaatgttt tttgatattg
     9961 atgccgatta ttatttgatg gtagatggtg atgatactta tcctgcagaa gctgcacatg
    10021 gtttgcttga gaaattacgt tctggcgaag cagatatggt cattggcgat cgtctatcaa
    10081 atggaaccta ttttgatgaa aataagcgtc ctttccatga ttttgggaat aatctggtta
    10141 aaaatacaat tacttactta tataaaacaa aaattcgcga tgtcatgacc ggctatcgag
    10201 gattcaatcg aatttttgtc aaaagcttcc ctattatgag ttctggtttt caaatcgaaa
    10261 cagaattgac gattcatgct ttagataaaa aattcaagtt cgttgagatt ccaatcgatt
    10321 atcgcgatcg tcctgaaggt agcgaatcaa aattgaatac attctctgac ggattcaaag
    10381 tgatcatgat gatcatcaaa atgtgcaaag attataaacc tttgcttttc tttgggatct
    10441 ggaccatctt cttcttttta tttggattgg tcatggggat tcctgtgatt cgtgaatata
    10501 tgctgacaag ctttattaca cgcatccctt ctgcgatttt aagtactgga ttgatgactt
    10561 tagcccttct ttcattagta acagggttga ttttggatac ggtcgtcaca aatgccaaga
    10621 aagaatatga attgaattta taccatgtct accacgaata tcaaaataaa gaaatgaagt
    10681 aggaggcctt ttttatgcat aagaaaaagg agaatctatt tcctactttt tttgcaactt
    10741 tatttgcgtc aggttttgct ttttttactt cttatggtct aggaactttg aatccaacag
    10801 taatcattgg tttagccatg gttttgctac ttgcttttaa gcaatatgga atagagttgt
    10861 tttcaataaa aaacaaagtt gcagctattg cccgattgtt tttttctgca gcttttgctc
    10921 ttacactttc tattggcaga cagatacaat ttcagtatgt ctcagcaaac tatacaaaga
    10981 caacgattgc tgatggaagt attttttact ttcttgttta tttctccatt tttgtgtatt
    11041 cttttttatt tttacaatcg atttatttat caatgccaaa actggaaaca ttttttactg
    11101 ctcaaaacac acaggctttc tcttcaagaa aatatttttt attctttact gtctttttag
    11161 ttctgtgttg gcttccttat ctgttggcat tgtatcctgg agtggttttg cctgattcgt
    11221 taagttcggt cgcccaatct atgggtgatg ttcctataag caatcatcat ccagtcttat
    11281 tcaccttact ggtcaagcta tttgttcatg atttaccaac tgatacgatc aatcacggtg
    11341 tatttttatt ttcgattttt caaacattga taacagcttc agcgataagt tattctcttt
    11401 gctggctgtt aaaaagaaac atccattttt ttccggtact cattagttta tgctattttg
    11461 catttgcacc ggtttttcca atctacgcct tgaacatgca aaaagatact ttgttctcta
    11521 tcgcttgctt tttattttcc ttagcggttt ttgactttat ttttcaacga gaaaagccaa
    11581 cgattctcaa tcagatttac gtaatcatcc ttgctttact gaccacctat ctaagaaata
    11641 atgggattta tgtagtaacc ggcacaggtt tgatttgcgg cttgattatt ttgaaacaaa
    11701 aaaggtatca agcattcttt caagtggtgc tgggttatac agtgattgct ggactactca
    11761 tccacccgtt gatggctcgt tatgctattc ctacagaaac tgctgaacaa ttaggtgttc
    11821 ctttgcagca aatttctaga actattgtta tggatggtga cttgtctaag aaagataaag
    11881 cattcatgaa tcagctactc ccgataaaag attatgaagc gtattctcct agtcttgcag
    11941 actcaatcaa gtggcataaa aattttaaca atgagttttt gaatacacat aaaaaagaat
    12001 ttctatcact atgggcaaga aatttaccaa gtaatataaa aatctataca gatgcttata
    12061 ttttagaaac gttcgggttc tgggtacctg gtacaaaaaa tagttacggc tttttagata
    12121 ctcgtgtaaa cacgaataat tatggtatga agcaagtaga tttgattgaa catcttactg
    12181 gattgtcagg aatgaaaaaa atcatcgatg ctcgtgattt ctttggttcc ggcacattac
    12241 tgtggttagc tatcggcagt gcacttttag caatctttaa gaaaaaatat cggtatttac
    12301 tcctttttct tcccggtatg cttgtttttg ctactattat gattgctact cctgtggctt
    12361 ttagtttacg gtatgtgttt gttttagcat taggtctacc tgtttatatc ctctctcctt
    12421 ttttactaga taaaagagaa aaaatgaaaa cagatatagg agatactcat gaaactattt
    12481 aaaaagatat tttttgcttt tgttctcttg atcgctagct attgcgtact actgacaatt
    12541 acttttttca ttccgcagca ctctattgaa tcgaatgcag aaaaatctct acagatggtt
    12601 gaaaaagaag gaatgtatcc ttctatcaat caaggaaata tgctaggcac tcggttagat
    12661 aattttactg atcatttgat gatacgaaaa acaaaagcag atcctgaatt gaactccttg
    12721 gagaacgcga tgtctatggc ggattatccc cgttattggc atggttatca gcttttttta
    12781 cgacctttac tgctagggat gagtttgggg agtattcgaa tgatttacgc agccattctt
    12841 tttctgctga ttggattgac gagctacttt ttaaccaagt gtagcgacat ctatttaacg
    12901 acagccttgt tgatttcgct tgctatagga aatgctgcaa cctttttctt cagtatgcaa
    12961 ttttcaaata tttggatttt gactttattg tctgtattac tatttttaac aaaaccacaa
    13021 ctctccaaca ccaaccaaca attattcttg tatttctttg tcattggttc tttagctaac
    13081 ttttttgact tgttgacaac accggtcatc tcttggggga tacctgtgat cattatttat
    13141 tatgtaacaa ataagtattt aatggataaa cgcagttcat tgagcaaaca agtaggcagt
    13201 tttgttttta ccggtatctt ttggggatta ggctatggtt tgacatgggt ggctaaatgg
    13261 atcctatcat cgatcatatt gaacaaaaac attgtaaaag atgcaatcaa ccaaatcctc
    13321 tttcgaacgg aaggaaacga caaatacccg ttgcatcgat tagagatgct gaaaagcaat
    13381 attagattga tgtatccaaa agtagcaata ttattgctat tgattacttg tcttgttttt
    13441 ctctattttg cttatcgtaa acgaaatagc tggcgtccgt tccaacttct agttttgttt
    13501 gttttagctg ctgtaacgcc gtatatttgg tacaatattt tagctaatca ctcacagatt
    13561 cattattggt ttacgtatcg tacgcaaatc atcacaagtt ttgctatact tagtgctttc
    13621 gcctttttga tccctcctga gaaatcaaaa gacgaactaa attactttta agaataccga
    13681 tgtactaatt catttttaaa cataaaaact ccagctgtca gagatagccg ga
//
LOCUS       DAPBCF010000064        13337 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.065, whole genome shotgun sequence.
ACCESSION   DAPBCF010000064 DAPBCF010000000
VERSION     DAPBCF010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.065"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(180..737)
                     /gene="frr"
                     /locus_tag="RD508_002382"
     CDS             complement(180..737)
                     /gene="frr"
                     /locus_tag="RD508_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDT7736916.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(740..1462)
                     /locus_tag="RD508_002383"
     CDS             complement(740..1462)
                     /locus_tag="RD508_002383"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDT7736917.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1598..2479)
                     /locus_tag="RD508_002384"
     CDS             complement(1598..2479)
                     /locus_tag="RD508_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDT7736918.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2578..3360)
                     /gene="rpsB"
                     /locus_tag="RD508_002385"
     CDS             complement(2578..3360)
                     /gene="rpsB"
                     /locus_tag="RD508_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDT7736919.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3719..4198
                     /locus_tag="RD508_002386"
     CDS             3719..4198
                     /locus_tag="RD508_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HDT7736920.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4415..5506
                     /gene="phnW"
                     /locus_tag="RD508_002387"
     CDS             4415..5506
                     /gene="phnW"
                     /locus_tag="RD508_002387"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HDT7736921.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5499..5627
                     /locus_tag="RD508_002388"
     CDS             5499..5627
                     /locus_tag="RD508_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HDT7736922.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5631..6176
                     /locus_tag="RD508_002389"
     CDS             5631..6176
                     /locus_tag="RD508_002389"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HDT7736923.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6630..8321)
                     /locus_tag="RD508_002390"
     CDS             complement(6630..8321)
                     /locus_tag="RD508_002390"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDT7736924.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8741..9688)
                     /gene="arcC"
                     /locus_tag="RD508_002391"
     CDS             complement(8741..9688)
                     /gene="arcC"
                     /locus_tag="RD508_002391"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDT7736925.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9803..10822)
                     /gene="argF"
                     /locus_tag="RD508_002392"
     CDS             complement(9803..10822)
                     /gene="argF"
                     /locus_tag="RD508_002392"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDT7736926.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10913..12142)
                     /gene="arcA"
                     /locus_tag="RD508_002393"
     CDS             complement(10913..12142)
                     /gene="arcA"
                     /locus_tag="RD508_002393"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HDT7736927.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            12603..13304
                     /locus_tag="RD508_002394"
     CDS             12603..13304
                     /locus_tag="RD508_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDT7736928.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
BASE COUNT         3753 a         2711 c         2368 g         4505 t
ORIGIN      
        1 acttaaaaga ttcccactat cttaagtatt atagcaatat ctaactgttt ttcctatgaa
       61 atcattgttt ttttatttaa aaactgaata attttttctt tttttaattt ttaaataaaa
      121 gaaatataaa taaaaacaga ggaagcggaa tgatccgccc ctctgttttt atgattttat
      181 taaacttcca ataattcttt ttctttatca gcagcgatct tatctacttc tttgatgctg
      241 ttatctgtca atgtttgtac gtctttttct aatccgcgca aatcatcttc ggtaatatca
      301 ccattttttt gttgtttttt atattcatcg atcgcatcac gacggatgtt acgaatcgcg
      361 atttttgcat tttctgcttc ttttttcaca tctttagcta attcttttct gcgttcttct
      421 gtcagttgcg ggataactaa gcgaatgaca tttccatcat tggttggact gattccgata
      481 tcacttgcca taatagcttt ttcaacatct tgaagaatgc tcttgtcaaa aggtgtgatc
      541 attaaaacac gtgcttctgg aatttggatt gatgccattt ggttcaatgg tgttggcgca
      601 ccgtagtagt tcacagtaat acggtccaaa aggctagcgt tcgcacggcc tgcgcggatt
      661 tgcccaagtt cacgttgaag attttgtgct gcttttttca ttttttcttt tgcttctgtc
      721 ataattgcat ctgccatttt tatttccccc ttacagttgt tccgatattt tcgcctaaga
      781 ttgcacggcg aatatttccg tgttcattta aattgaagac aagcagtgga atatcattat
      841 ccatgcttag tgaacttgca gttgaatcca tgacttgtaa tcctttggca ataacttcca
      901 gatgagtcag ttcttcaaat tttactgcat ttgcatctac tttcggatca gcagaataaa
      961 caccgtctac attgttttta gccatcagga taacatctgc gccgatttct gccgcgcgta
     1021 atgctgctgt tgtgtctgtc gagaagtacg ggttgccggt accgcctgca aagataacga
     1081 tccgtccttt ttctaaatga cgttctgctt tacggcgaat atatggctct gcgatttgac
     1141 gcatttcaat cgaagtttgc acgcgtgtcg gtacacccac gttttccaac gtatcctgta
     1201 aagctaaggc attcataact gtagctaaca tacccatgta atcagcttga gcacgttcca
     1261 tgcccatttg tgctccgatt tgtccgcgcc agatatttcc gccgcccaca acgattgcca
     1321 tttcaacgcc cagctcgtga acttctttga tttcttggat gatttctttg attactggtg
     1381 gtttgattcc aaatcctgcg tccccagcta aagcttctcc actcaatttt aagactacac
     1441 gctgatattt cggtgtgacc atgttcattc ctccaatatt ttctattgcc attttaccat
     1501 acttagatga tttcgacact ctaagactgg tttttcttgt tttgcttaaa aaaagggagc
     1561 gcacaaaccg tgcgttcccg tctgttattc aacagaatta ttttttcact tggctcataa
     1621 cttcttctac aaagttatct tcgcgttttt cgataccttc gccaacttcg aaacgtacga
     1681 atgttttaac agttgcgcct tttgatgcaa cgtatttttc aacagtcata tcaggatctt
     1741 taacgaatgg ttggtccacc aaagcgattt ctgctttgaa tttcttcaag cgtccttcta
     1801 ccattttttc aacgatattc gctggtttgc cttcgttcaa tgcttgttct gtaagaacag
     1861 ttttttcatg ttctaattca gcttctggaa tttgtgattc gtttacataa cgaggattga
     1921 tagctgctac gtgcatagct acgtctcttg caactgtttc gtcagttgtt ccatctagaa
     1981 cagtcaatac ggcaatacgt ccgcccatat gcaagtatcc accaaatgca gcattgtcgt
     2041 ctttttctac aacttcaaag cgacggaagc tgattttttc tccgataact tgagttgctt
     2101 cgatcaagtc agattcaatt gtacctttat ctgttttgat tttcattgca gcttccatgt
     2161 ctgctggttt gttttcagca acaagttctg caatttcttt tactaaatct tggaacattt
     2221 cgtttttaga aacaaagtct gtttctgagt ttacttcaac gattgctgca gtgttacctt
     2281 tcacagcaac tgaagccaat ccttcagctg caatgcggtc atttttcttc gcagcctttg
     2341 ccattccttt ttcacgtaaa agatcaactg ctttttccat gtcgccttct acttcaacta
     2401 atgctttttt cgcatccatc attcctacgc cagtcatttc gcgtagttct tttaccattt
     2461 tagctgtaac gtctgccatg tttaactcct cctgtgtgtt tttcttttta aaaaaagctg
     2521 cttcaaagga gagtgaggct tgtcgcccag cctttgaaac agctccatca ttcaaaatta
     2581 ttctgctgaa gaattgtcgc cttcaacaac atctacgatt tcttcgattg atgttgctgt
     2641 gttttcttct gtgaaatctt cttcaactac ttgatcttca ccttggtttc cttcgatgaa
     2701 agcatcagcc atttttgaag taatcaattt aacggcacga attgcatcgt cgtttgaagg
     2761 gattactacg tcgatttcat ctggatcgca gtttgtatca accatagcta cgattgggat
     2821 atttaatttg tgtgcttctt gaacagcaat acgttcttta cgtgggtcaa cgatgtacat
     2881 tacatctggg attcttggca tatcagcgat accgcctaag aatttttcaa gacgttcacg
     2941 ttctttgttc aaaccagcaa cttctttttt aggtagaact tcaaaagttc catcttcttc
     3001 cattgcattg atttgtttca aacggctgat acgtttttgg atagtatccc agtttgtcaa
     3061 tgttccgcct aaccaacgat ggttaacgaa gtattgtcct gcacgagttg cttcttcttt
     3121 gattgcttct tgtgcttgtt tttttgtacc tacgaataat gctacgccgc cttcttcagc
     3181 aacgctcttc atgtaatcat aagctgcatc tactaattta actgtttttt gcaagtcaat
     3241 gatgtagatt ccgtttcttt ctgtgaagat atatttcttc atttttggat tccagcgacg
     3301 agtttggtga ccaaagtgta cgccggcttc tagtaattgt ttcatagaaa ttactgccat
     3361 gtttgtttcc tccgatttgg ttttattttt cctcttctta tcttctacct tgccggcaaa
     3421 ctttttcaag cacctaccga caatccaata agaatgtgga tttgctgatg cataaagcac
     3481 cctcagctat tatacagaca aaagatccgt atcgcaagag caaatatact tttctgctca
     3541 acattcaata gtttacctga aagataaaaa gaattcaaga aaaacagtag atttctcttt
     3601 gtttctttat tatccttttt ccataaaata attttaggta taaaagacga atattattgg
     3661 gcaatccttc ttttttttgt tatgatacat gtgaaatctt tcgtaaagga gaaagaaaat
     3721 gcgcaaagct caaagacatt tgctgattaa acaagtcatt gaagaattcc cgatccgtac
     3781 gcaagaagaa ctattaaaca aacttgggca ttatggcgtt accgccacgc aggcaacgat
     3841 ttctcgagat atccgtgatc taaaaatcgt gaaggcacct gatgaaaatg gcgtttcccg
     3901 cttcgtattg tttcgcgaaa aaggaactcc tgagactagg actgaggaag aggatcggct
     3961 ggttcaaatg attgaagaca ttgtattgaa agtcgaacga gtccactttt tgacgatcgt
     4021 caataccttg ccagacaatg ctcatttatt tgcatctgtt ttagatgaga tcaaacctcc
     4081 ctctattgtc agtacaattg ctggattcga tacgatcatg gtcatctcgg aaaatgagga
     4141 ggacgcaaaa cgagtagaag aatttcttca ccatccaact gaagtatcac ttttttaatc
     4201 agagcacgta ttcctaatat ggaatgcgtg tttttttatt ttcaatattt tccttattga
     4261 ataaaccttt acactcttta caaaaataca tcatttttta ttcaaatttt tcaacacctt
     4321 gattgaatca caataatcat catttatatt ggatgttaac aagagcagct tcttgctctt
     4381 tgtgtatttc aaaaaagaaa tgaaaggaaa tcatatgtat aaattattaa cttctggacc
     4441 attgacgact tctgaaacag tgaaaaatgc tatgctgatc gatcattgta cttgggatca
     4501 agaatacaaa gaaattacac aatggataag aaaaaaatta ttggatcttg ctcaagtatc
     4561 ggaaggaata tacacaacgg tcttaatgca aggtagcagc tccttcgggg tagaatcggt
     4621 attaagttct gtgatcaggc cagaagatac tgtactgatt tgttcaaacg gcgcatatag
     4681 acaacgaatg atcaacatgt gcgaatgtct gaaactgaac tataccgttt atgaggtatc
     4741 ggaacatcaa atcctccaag ctcatgtgat tacacagctg attgaagaga atccgtctat
     4801 ctccgcacta gcaatggtcc atagcgagac tacttccggt attttgaata atttggaaga
     4861 gattgctgct gtcacacaag aaagagatct tttgtttata gtggacgcga tgtcaagctt
     4921 tggtgggata ccgatttgtg tagccgaact agggattgat tttttgattt ccagctcaaa
     4981 caaatgtatt caaggtgttc caggcttttc ttttgtactt gctaataaag cggaactgga
     5041 aaaacgaaaa aatgttagcc gaagtttgtc acttgatcta tatgaccagt accgcgtgat
     5101 ggaaaacgag aatggcaaat ggcgtttcac ttcccctacc catacggttt tggcttttca
     5161 acaagcgctg aaggaactag aggcagaagg aggaatcgaa actcgatatt cacgttatct
     5221 cgccaataat catgtgctac gacaaaaaat gacagagatg gggttccagc ctttcattca
     5281 agaatatcag gggccattca tcacctcttt tctttaccct aaggactggc gatttgattt
     5341 taatcatttt tatcagtatt taaagcaaaa tggatttgtg atctatcccg ggaaaatcag
     5401 cgatcatgaa tgttttcgta tcggaaatat tggcgagatc tatccggaag atattttgga
     5461 actgacagca attatcaaag actataagga gaacgttaat gattaaaact gtaatttttg
     5521 attgggcagg aacaactgtg gactttggct gtatggctcc tgtccacgct tttagaaatg
     5581 cttttctaga aaaaggaatc caactgactg acaaagaaat ccgctaaccg atgggaaaat
     5641 taaaatggga tcatatccaa cagcttcttt ccctcccttc tgtcaaaaaa caatggatag
     5701 ctatttatgg acaactacct caggaaaaag aggtggagga attgtatcaa caatttgaac
     5761 attatctgtt taaagatttg gtcaagcatt ctaccttgaa acccgacaca ttggaaacga
     5821 tcgaacggtt gagaaacgct gggatcaata ttggttccac gaatggattt aatgctccta
     5881 tgatgacaat cgtagcagaa accgcaaaaa aagaaaggta ttcaccagac ttcatggcaa
     5941 cttttgaaga cgtcgaaggg tatggtcgac cgtttcctta tatgatccat aaaaacatgc
     6001 agtacttcaa aaacaagtcg gttgatgaag taatcaaagt cggagatacg gtctcagata
     6061 tccaggaagg gaaaaatgcc ggagtgttga cagtaggtgt aattgaaggt agttcgctaa
     6121 tggggatttc ttatgatgag taccaaaaat tagagatggg gaaaaagatc gtttaaaaca
     6181 gtctgttgct cttagattcc aacaagccgg cgctgatatt tgtgtaaaca atttaaaaga
     6241 gttaacagaa tacattttgt acgctgacaa gaatccagaa tgacttttat acaaaataag
     6301 aggttgtgaa aaagctgtcc tgtatcaagt aataaaaaca gccaagcaaa aatagctcct
     6361 catatttttc gtttggttag gcttattacc gcagatgcaa gcttttgaac accgtttatt
     6421 cgaaaaaaaa aagggagctg tgacacgact tttgtcacag tccccttatt tgcaaacaaa
     6481 cagtgtttaa gagacaacct ctccactaaa cggtgttcat tcagctgact ctcggtattt
     6541 gctcaaaaaa cgataaaatt tgaaaagcta ttttctcttt tgtttctcta atactcggat
     6601 cagaacgctg atttcacatt ctctttttct tacatcttat ctggtgcatg aagtcctagc
     6661 aaacgaaggt cttctttcaa taatacagtc actgcataaa ctagagctaa gcgtgcttct
     6721 ttttgttcat catcagctaa aatcttcgta tgagcatagt atttgttgaa tgcttgtgct
     6781 aatttgattg catgtttcgc aatcactgac ggttcgtatt tttccccagc agacaagacc
     6841 gtttcagggt atttttgaac taatttaacc acttcccagc tggtatcgtc attcaatgca
     6901 tagtctgctg tttctgaagg gacaaatcct gctttttcca acaggctgac tgcacgagca
     6961 tgtgtatatt gcacataagg tccagtttct ccttcaaatc gaacaacttc ttccaggtta
     7021 aagtcaaatg tattcagtcg atcgtttttc aaatcgtgga aaatgactgc cccaacccca
     7081 acttgtttag ctacagcatc tttgttttcc aaatcagggt ttttctcgct gatttgttct
     7141 ttagcagatt ggattgcttc atttaatact tcttctaata agacgatctt tcctttacga
     7201 gttgataatt ttttaccacc ttgcgtgatc aaaccaaatg gaatatggtg catgtcgtca
     7261 gaccagtcaa agcccatttc cttcaagaca gctttcaact gtttaaaatg atagctttgt
     7321 tcattcccta ctacatatag agattgtttg aagtcgtaag tacgtttacg gtacaatgca
     7381 gcagctaagt cacgtgtaat gtatagtgtc gcaccgtctg acttcttaat caacgctgga
     7441 ttcaggtcat aagcagatag gtcaacgatc tctgcacctt tatcctcgtt cagcaaatgt
     7501 ttttcttcta aaagtttgac gatttcatcc atcttgtcat tgtagaaagc ttcaccgttc
     7561 aacgaatcga aacgtacttc cagcagatca tagattttat tgaattcttt catcgattca
     7621 tcacggaacc attgccataa ttgaatagcc tctttatcgc cttcttccag acgtttgaac
     7681 caagcacgag cttcttcatt taattctggt tctgtttcag ctacttcatg gaattggacg
     7741 tataaacgaa gcaattcatt gattggttct gctttaacag cttcttctgt accccatttt
     7801 ttgtaagcga cgatcagttt tccaaactgt gttccccagt cacctaaatg gttgatgcgg
     7861 attggctgat aaccgatttt ttccataatg aaaccgatcg aattaccgat aactgtcgaa
     7921 cgcaaatgtc ccattgagat tggtttggca atattaggag aagacatgtc gattggtact
     7981 gttccttgat tcccgatgtt gctatcccca taatgttctt tttctttcac tacggtttgc
     8041 aaaacttttt tgctgataag ttctttattc atgaaaaagt tcaagtaagg tccgacaact
     8101 tcgatttttt caaagttggc agaatcgatt ttttctgcta aatctgcagc gatttgctgt
     8161 ggcgcttttc ggtaaacttt tgctaatgaa aaggctggaa atgcaacatc tccgtgttca
     8221 gctgattttg gattttctag taattgctcg acttgttcca gtgttaaatc atctttgaca
     8281 gcgtcataga cagcttttgc gacaagatct ttattattca tctttattcc tcctaaagtg
     8341 ttcccttgat tgttaaacaa aaaaaatctc tagcgacggc atacttagta tgccatcact
     8401 agagacgaga tttcccgcgg taccactcca attgtcctaa aaaaggacca gctccatctg
     8461 atatcggtag acgaccgtct gtttaaaaca gaattctcca agtgcgcttc gttgtatctt
     8521 cttcattcgg cttccaccac ttccgaattc gctagccaag aatgatacaa gtactctctt
     8581 gttcaacaaa tcttagtctt attaaacttt cttgaattat atcagaaaaa aaaacgaaag
     8641 gctagtcgtt tcataaaaaa aaaatccaga tggcctaaag gagaagaaat accacctgga
     8701 tagctataaa tcatttcgta aatacgaaag acttaacaaa ttaatcagct acgataatcg
     8761 ttccttcttc agaagctaaa agattctcga tattttctaa agaagtgatg attgccttag
     8821 cgtttggttt tgcttcaaca aatgcaatag ctgcttctac tttcggaagc atgcttcctg
     8881 gagcgaattg cttttcatca atgtattgtt tcatttctga aacagtaaca gtttctaatt
     8941 tcttttgatc tggtttttgg taattgacat acacattgtc tactcctgtc aatacgatca
     9001 gcaaatccgc atcgatgatt tcggctaatt tttctgaagc aaaatcttta tcgattacgg
     9061 cttctcgtcc ttctaatcca gtagctgttt ctacaacagg aatcccaccg ccaccaacag
     9121 agactgtgat aactccttga tcgaccagcg tttcgatgac acgtgcttct ttaatcgaga
     9181 tgggtttagg ggaagcgact acttttctcc atccacgtcc agcatcttct ttgaatgtca
     9241 cagtggagtc agcattcatt tgttctttgg cttcttcttc cgtgtagaat ggaccgactg
     9301 gtttacttgg atttttgaat gaaggatcat tttcatccac aataacttga gtgactaaag
     9361 aaaccacatc tttatcgatc cctttttcct tcagtacttc gcccatggcg ttttgtaacc
     9421 agtaaccgat agatccttct gtcattgcaa cacatgtatc taaaggcatt gccggtgttt
     9481 tctcagaatc agcagcttgc tgctgaatca ataggttacc gacttgcgga ccatttccgt
     9541 gggagatgat caattcatct ccttgttcga taaatttcac taaatacttt gctgtttcca
     9601 ttaacgcttc ttgttgggct tttgcacttg catccgtaga caagatggca ttgcccccta
     9661 aagcgacaac tacttttcgt ttggccattt cattcgtcct ttcttcagtt ctaccgaatt
     9721 ttctagataa caaaacgagc cagcgttttg tgattttccc tcaatgctga ctcgtttttt
     9781 cgtgagatga atgtggttat gcttaaacgc gagggataaa caagttacct aatgttgctg
     9841 ccatgatcgc tttgattgag tgcatacgat tttctgcttg gtcaaattga cgagcatatt
     9901 tgctgcggaa gacttcatct gttacttcca tttcagtgat gccaaagcgt tctttcattt
     9961 gttcaccgta aacagtgttt gtatcatgga aagctggcaa gcagtgcaag aagatcaaac
    10021 gatctgtgtt gtgtgttttt tctaccattt ccatattgat ttggtaaggt ttcaacaatt
    10081 tgatacgttc ttcgaattta tcttcttcac ccattgatac ccatacatca gaataaagga
    10141 cgtctgctcc gtctacacct ttatcaacat cgtcggtaat catcaattgt gcaccggatt
    10201 tttcagcaaa gccttctgcc attttgacga tttcttcttc aggttgtaat tcttttggtg
    10261 caacgatacg catattcgct cctaaaattg cacctgtgac taataaagag ttagccatat
    10321 tgtttcgacc atctccgcag taagcaacag tgataccttc tactgttcca aagttttctt
    10381 ggatagttaa aaagtcagcg atcatttgtg ttggatgcca ttcatcagtc aagccattcc
    10441 aaactggaac accagagaat tctgctagtt cctctaccat tttttgactg aatccacgga
    10501 attcgattcc gtcaaacata cgtcctagta ctttagctgt atcttctgtg gattcttttt
    10561 tacctaattg gatatcattt gcacctagat attcaggatg tgcacctaga tcgatcgctg
    10621 cagtagtaaa tgcagaacga gtacgtgtag atgttttttc aaataaaagc gcaatatttt
    10681 ttccttctag atagtgatgt gggataccac gttttttcaa gtctttcaag tgttctgaaa
    10741 aatcgatcaa atattgtaat tcttcttttg taaagtcttt ttctgctaat aagcttcttc
    10801 cttggaatac tgattctttc atattaaaca ttctccttta gattgttttt atttaagatt
    10861 aaagaggaaa tcccgacggc agctgacagt aagactgccg tcaggaaaca aattacttca
    10921 agtcttcacg gacaagtggt tggctcatgc agcgtggacc accacgacct cgtgacaatt
    10981 cacttgaatt gatttctaac actttgatgc catagctacg aagcaattcg ttcgatacat
    11041 aatttcggtt ataagtgact acaacacctg gagcgattgc caatgtgttt gatccatcat
    11101 tccattgttc tcgaggtgca acgatctcat ctccattacc agttgggatc agtacaagat
    11161 catctaatcc aagagcagct ttcatcgttt cgtgtaagtt atctgaatga gtaatcttga
    11221 tatcatcacc atctggttcg attgtaaaga catccatctt accgtcttta ctttgaattg
    11281 ctggatggat agtgaattta tcgtgatcta ccattgtaaa tacggtatcc aaatgcatca
    11341 ttgcacggtt gttcggaatt ttgattgcca acactttttc aaatcctgaa ttttttgcga
    11401 ataggtggcg tgctaatttt tctaaagctt tcgcattagt tcgttgagaa atcccaacag
    11461 ctactacttt atcgcttaag atcaattcgt ctccgccttc gatatgatct ggattttcac
    11521 gatccaacca tacttcgatt cctttatttg caaatcttgg atgatgtttc aaaatatatt
    11581 ctgtaaacat cgattcacga cgacgtgctt caaaagtcat cttattgact gtcatcccat
    11641 ttcccattga tgcggaaggg tcgcgtgtaa agtacaagtt tggcattggg tccatgtaaa
    11701 atggatagtc atcgtctgct gacagatcat atagactgct agaacgtact tcgatatctt
    11761 ttgtacgaac cccagccatg attttatcta ccatttcttg cgtttccatt gatagaagga
    11821 actcatgaag accctctctt acagcattcg atgcaatatg agattcatcc aacattttat
    11881 tcaagaattg ttctttgaca ttgcctgcgt caatcgcttc tgccgctaat ttttccaagt
    11941 aaagagtctc gacgccttca ttttgcaatg tcttcgcaaa gttgtcatgt tcttcttgag
    12001 caatcggaag atatggaata tcatcgaaca acagacgatc cataatatct ggtgtcaaat
    12061 tttccacttc ttgtccaggc cgtttcagta aaactgtctt taatttccct atttcagaga
    12121 aaacgtgaat aggtttatcc atgttgtgtt gcctccttct ttttgattac atgtatagga
    12181 tatcctcctt ttgtaatcac tttcataatt ttgtctcatt caaaatgaga cattcctcac
    12241 attaatattc gataattaaa taattaaacg tttttctatt tttaagcgta atttattcat
    12301 tttttattct gtatacactt tcaaaaaaat atttattcat tgaaaaaatt tttttgaata
    12361 aattaaaaaa ataaattata ttatcgttgt tagcgtttac tatatgtatt attgttgttt
    12421 tttatacaca aatcattcgc ttcaaaacaa attattcaat accattgtat attttttaca
    12481 taataacaaa ttatatttgt aaagtattaa aacttgtttc taatgttggt atgttaaaac
    12541 tttacaaatt ctttaaaaaa agtgacaata aatatagtga acaataagga gaggactttt
    12601 taatgcgtgt taataaaatc gattttcact tttcaaaact cagatatcaa cctgattttg
    12661 aacatttctc ggatgaagag ttccaacaga tcaaggaaca tactgttctt cgttcttata
    12721 aaaaaggaca gatccttttc gacgatggtg atcccagaca acggttgtat atcttgacca
    12781 aaggactcgt tcgtttagaa cgttatgatg aaagtgcaac ttattactac tatgactatg
    12841 tgaatacaaa taaccttttt cctatgtcag gaatgtttgg agaagagacc tacacttata
    12901 cagctcaagc gatgactgat attgaaacat tctaccttcc tgtttcctac tatgaaaaat
    12961 tagcacgaaa aaatcccgaa cagttgatct atatgataca aaaaatttct aaagtagttg
    13021 aaatacatga attgcgtatc caaatcggat tgacctctag cgcctttgac cgggtaaaac
    13081 aaaatttatt cattttgaaa gaagaattgg gcgtaccaac aaaagatggt catatcacca
    13141 ttccttatcc gatcacctta aaagaattag cagtgaatag cggcacgaca cgtgaaactg
    13201 ctggacaagt aatcaaacaa ctacgtgatt ccgggctgtt agattatgac aaaaagcgtt
    13261 ttactttctg taagacagct actactccag ctatgagaga ataacgcgaa caaaaataag
    13321 cagtgaccct gataaat
//
LOCUS       DAPBCF010000065        13184 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.067, whole genome shotgun sequence.
ACCESSION   DAPBCF010000065 DAPBCF010000000
VERSION     DAPBCF010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13184
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.067"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..192)
                     /locus_tag="RD508_002395"
     CDS             complement(<1..192)
                     /locus_tag="RD508_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736929.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEK"
     gene            330..1844
                     /locus_tag="RD508_002396"
     CDS             330..1844
                     /locus_tag="RD508_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HDT7736930.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(2247..3230)
                     /locus_tag="RD508_002397"
     CDS             complement(2247..3230)
                     /locus_tag="RD508_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HDT7736931.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(3235..3882)
                     /locus_tag="RD508_002398"
     CDS             complement(3235..3882)
                     /locus_tag="RD508_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7736932.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(3967..4599)
                     /locus_tag="RD508_002399"
     CDS             complement(3967..4599)
                     /locus_tag="RD508_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7736933.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(4615..5166)
                     /gene="coaC"
                     /locus_tag="RD508_002400"
     CDS             complement(4615..5166)
                     /gene="coaC"
                     /locus_tag="RD508_002400"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HDT7736934.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNTITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(5163..5900)
                     /locus_tag="RD508_002401"
     CDS             complement(5163..5900)
                     /locus_tag="RD508_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HDT7736935.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(5897..6886)
                     /locus_tag="RD508_002402"
     CDS             complement(5897..6886)
                     /locus_tag="RD508_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDT7736936.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            7144..7686
                     /locus_tag="RD508_002403"
     CDS             7144..7686
                     /locus_tag="RD508_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7736937.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            7703..8788
                     /locus_tag="RD508_002404"
     CDS             7703..8788
                     /locus_tag="RD508_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7736938.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            8800..9606
                     /locus_tag="RD508_002405"
     CDS             8800..9606
                     /locus_tag="RD508_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7736939.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            9607..10434
                     /locus_tag="RD508_002406"
     CDS             9607..10434
                     /locus_tag="RD508_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7736940.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            10431..11504
                     /locus_tag="RD508_002407"
     CDS             10431..11504
                     /locus_tag="RD508_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7736941.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            11932..>13184
                     /locus_tag="RD508_002408"
     CDS             11932..>13184
                     /locus_tag="RD508_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7736942.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNE"
BASE COUNT         4145 a         2341 c         2758 g         3940 t
ORIGIN      
        1 cttttccaga aaataaggga tttcaaataa aattaatgtc agtaataaaa gcattgtatt
       61 tccccagtgt tggttccaga cctgatccac tagcataata acgacgatga tacgtaataa
      121 aatatagatt ccgtttgtga ttctacctgc agtttttgta ctgttcgtaa aaaaggtttt
      181 caaatgattc ataaaataac tccttcatgt atatccttaa ttatactaag aagcgtgtgt
      241 ttaccaaagc tatatgactt aaagaaaaac agagttgata ttgtgaaaaa aatcacttaa
      301 tatagtataa ggagaaaagg gggatacaaa tgaaaaaatt agttgctggt ttattaacag
      361 ccgttgcact tcttgctatg agcgcatgcg gcgcagatca gaaaaataca gcgcagacaa
      421 gttctagtac gaaggaatct gccgaagtat catcaggcgc ttctgaacaa gtatatacag
      481 atccaaaaga aatgaaagaa tcttatgatg tcgtgattat tggagctggt ggtgcaggga
      541 tggcagcagc tatcgaagca aaagatgctg ggttgaatcc agtaattttg gaaaagatgc
      601 ctgttgccgg aggaaacaca tctaaatcat caagcggtat gaatgcttca gaaacaaaat
      661 ttcaaaaaga agaaggaatc aaagactcga atgatgcctt ctatgaagaa acgctaaaag
      721 gtggtggagg aacgaatgat aaagaaatgc ttcgatactt tgtcgatcac tctgctgatg
      781 cggtcgattg gctagatcaa aacggtatca aactggacaa cttaacgatc actggaggga
      841 tgagtgaaaa gaggacacat cgtccgtctg atggctcggc tattggtgga tacttagtgg
      901 aggggttatt gaataacgtc catgagcggg aaatccctat ttttgtcaac gcagatgtga
      961 cagacattaa gaaaaatggg gaaacggtca atgaagtgac tgtacatgtt caaggagaag
     1021 aaccaaaaga ggtcaccgga aaagcaatcg tagttaccac aggcggtttt ggtgccagca
     1081 aagaatttat tgaaaaatat cgtcccgatt tagctgatta tattacgaca aatcaagaag
     1141 gatcaactgg agatggtatc accatgattg aaaaattagg tggacaaacc gttgatatgg
     1201 ataaaataca aattcatcca actgtgcagc aggatgaggg ggtcttgatt ggtgaggttg
     1261 ttcgcggaga aggagcaatc ttggtcgatc aagaggggaa aagatttgtc aatgaaatgg
     1321 atacaaggga taaagtatct gcagcaatta cagcattgcc tgaaaaatca gcttatttga
     1381 tttttgacca aggcgtgcgt gatcgtgcca cagctattga attttatgac caaaaaggat
     1441 atgtcacaac tggaaagaca atggaagaat tagcagaaaa aatcgattta ccaaaagaaa
     1501 cactagcaaa aacagttgat ggatggaata cggatgttgc ggagaaaaaa gatgctcaat
     1561 tcaaccgtgc cacagccatg gaacatgact tatcgtctcc gaattattat gcgatcaaaa
     1621 tcgcaccagg aatccattac acgatgggcg gtgtgaaaat caatacgaac actgaagtat
     1681 tagataaaga aaaccagcca attagggggt tatatgctgc tggtgaagtc acaggtggct
     1741 tacatggaaa caaccggatc ggtggaaatt cagttgcgga gatcattatt tttgggcgac
     1801 aagcgggcat acaagcagct cgatttgctt cggaaaatga atgaaataga acgtaaataa
     1861 aaagaggttg tgaaatcagc gttttgagct aataccgagg gtcagctgat tgaacactgt
     1921 ttagtgaaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag ccaagtaaaa
     1981 acagcttctt atgtttttaa cttggttgga cttattaccg cagatgcaag cttttgaaca
     2041 ccgtttattc ggaaaaagag cgtgggacaa aagtaaagaa cacttttgtc tcacgctcta
     2101 aacacgtata aacggcggaa gcagaagaaa ttccttcgga aataagctga aattcacaaa
     2161 aatttgaaaa gcaattttcg tgaatttctt cttatttctt ggagttaaac gcttctgtcc
     2221 cagcctcttt tttgatcagc atgattttat tcagttatct tcaaaatgat ttttccgatg
     2281 tttttgtttg cttccatata ttcatgcgct tgtttgactg cgctgaattg gaatgtacgg
     2341 tcaatgattg gccgaatctt gccattttct agaaaaggcc cagctttttg cataaaagtt
     2401 tgtgcgagct ctgctttata ctgatcactt ctaggtgtca ataatgtacc aagcagttgg
     2461 acacgtttcc caatcaatac accaaggtct atctcaggca cgatggtccc acctagcata
     2521 ccaatcaaga cccaacgtcc atcaacggct atagaagcta aattcttttc ccagtaagaa
     2581 gcgccgatga aatccaaaat aacatcgact ccccgacctt cagtgatttt tcgtacctct
     2641 tcttgaaagt cttgtttttt atagttgatc aattcatctg caccaagttc tttacaaaag
     2701 gcgagttttt cttctgatcc tgcagtaacg atgattttcg cgtgagaaag ctgtctagct
     2761 aattggatcg ctgctgttcc cacaccactt gctcctgcat ggatcaagac agtttcgcct
     2821 tcttgtaatt ttccaagcca gtaaagtgtt tgataagcag tcaaaaaaac ttctgagatt
     2881 ccagcagcag aaacatagtc tagcgtatca gggagaagga ttgcacgatc ggcaggcatc
     2941 acagcatatt cggcataacc acctagattg actaatccgt atacttttgt cccaggagta
     3001 aaagtggaga tatcactttt attctcaact acctctccag ctacttcgac tcccaaaata
     3061 gggtagggag gtttcaaaga gactgattct cttttcataa tatctgttcg attgacagct
     3121 gctgtatgga ctttgatcag taattcgcct tgttttggtt taggaacagg cacttcaatt
     3181 tgttctaata catctacaga accaggatgc ttgattgaaa tggcacgcat ggatctattc
     3241 ctcctttgcc cattcttgga atgctgtatt caactctttg ctaccttcag aaagtactag
     3301 agtcgtacga gaaatatccg tttcttccac tagagcggca agtacagcag caactgtaga
     3361 gcgagtgatc gtttttgatg ccttctcatt aggcttagtt aattgaatgg aagtaacttc
     3421 ttcatcgtta gtcaatgtga ctggttgaag aatgacaaaa tctaagttag ttcgtttcag
     3481 ccattcatct gcataatgtt tagtaatata ataatctgtc atggactcag gccattttgc
     3541 tggttcatct gcataaacag cactgaccat cagatagcga gagacatgcg cattttcagc
     3601 tgcgatcact gttttgattg cgccatccaa gtctacttgc agaagattct ttccttgaga
     3661 gccggcagca aaaatcaata catcgatgcc tttgaatgct tcggtcattt tttccacgga
     3721 ccaagttaaa tcaaaagaga catacgaaac attctctttt tttactaatg tttgggaagc
     3781 aacatctctc acccctgcaa aaatttcatg ggaacttgga gctaaatctt ttatcaggtg
     3841 tcggccaatt tgtccgtttg cacctacaac aaaaattttc atttggatca tcctttcgac
     3901 gtcaaatctt tccattcaat agtaacacca aaagagaaaa aaatcagaga tcggctacga
     3961 tgactatcag ttagtaagag aagggtgctt gaagtatctt aacaagacat tgcatactgc
     4021 tgcagtcgca agacctgcga cgattccttc aggtatacca cttgtaaaaa taaccgctag
     4081 aatagctgaa taaacagcat ttaaatttgt tccgatgact ttggcataat cttgctggaa
     4141 taaaaagtag atcatattca tcactaaaat cgtattggtc aatgaaccgg aaagtccagc
     4201 taagaataaa gaaacggaat ctgctttttg tttcattagt ttgcgcagac ctttataaac
     4261 gaaataagga accaccccaa tcaagatgcg aggaataaac gcgatcagca aggctttcca
     4321 gcttccatgt tctgttccga tgactgggat aaacggagaa aagacaaaag acaaaggtgt
     4381 ttggataact gtgctacgga tcatgctgat cagtccaaat gtaccgccaa gaaaagcacc
     4441 tagtcttggt cctaaaacga tcgaagcaat gattacagga atatgcatgg ttgttgcatt
     4501 gattggaccg atagggataa aacctaaagg cgtaacagct aataaaatca aaatagctaa
     4561 aaacatcgca gttaatgtaa agttttttgt atttttcata agtactcctt ttttctaagc
     4621 atttctttca ttaagagtca gcatgacctg ttcgatgatc gtctgaatat cagctaaggc
     4681 accttttcca aaatctccac aagctaaaag agattctctt ggttcaattt cctgatagcc
     4741 gacagatctc aatgtttcca gattacgctg agtgatcgtg ttttgataca tattcgtgtt
     4801 catggcaggg gcaatcaatt ttggtgttcc cactggaagc gccattgcga ctgttgaaag
     4861 aagatcgtct gcaatgccat ttgctagctt gccgataatg tttgctgtag caggcgcgat
     4921 gagaaacaag tcagcttgtt ttgctagttc gatatgattg attacctgcg gatttgattc
     4981 ttgcatgacg tctgtatgga ctgcgcgctt cgacagagat tgcaaggtta atggcgtgat
     5041 aaaatgtgtg ctgcttttag acataatcac atctacctgg gcacctaatt tgacgaattg
     5101 acttgtaaga tcagcgcttt tgtaagcaga aatacttcca gtaacgccta gtaagatctt
     5161 tttcattttg attcctccag tctaattttc tcagtaatca atgcagcaat ctcagattta
     5221 ctttgagctt cttccactgt tccatcttta gataagagat agccgtggtg tgtctcgcca
     5281 tggatttccg tcaaatcatt tgcgaaaata aaatcagttt tgttatttat cagactattt
     5341 tttgcgactg ccagaagaga ttcctttggt acatctacta atagtttgaa accaatgatt
     5401 tttgcttttg gctgccattc acgtagataa gaaatgattt ttggtgtttt cttcaaaacg
     5461 agcacaagat gctcggtgtt agaagagatc tttgaaacag tggtatctgt ctgttcattt
     5521 tccgcaaacc aattgtccag ttcttcttgc gttgaagaag tgggtaggtt ttttgccagc
     5581 tgttcttctg aaaaactaaa agcaggagta aaatcactga ctgccatact gtggataatc
     5641 gcatcgtagt gttctttttt cgttagttct tctaattgta aaaataagtc cagtgcagat
     5701 tcgatcgtat aaatcgttat attggagtgt cttttcggtt tcagtgcttg tttcgtagtc
     5761 acgtaatcga ttgtggtatc cggattggca gctaaataat cagctaatgc ttgccctaat
     5821 cgtcctgtcg aatgatttgt aatagcacgt acttgatcga ttttttcagt cgttcctcca
     5881 gctgtgatta gaatcttcat ttatggtcac ctacatttac tagtgttctt ccttggtgtg
     5941 ttccagcaag tagtttagat gctgtttcag gcaattgatc cagagtaatc tcttggacga
     6001 ccagttcatc tgcaatctgc aaatccgcca tctgttgcca taaagaaaga cgttgatcta
     6061 ttggtacatt gacagaatca attccaatca actggatgtt tcgcagaata aaaggcaaga
     6121 cagtcgcgtt tagtttgatt cccccagcat tgccacataa agctactgca ccgttataag
     6181 agatcaatgg aagaagactg cttagctgct cgccacctac tgtgtcgatg acatagtcga
     6241 tttgctgttt tcctaaagct tttgttgtct ctggcagaaa ttcatcaggt cgtacgactt
     6301 gcaaagcacc tagacttttt agccatgtga cagactcttc ttttctggaa aaggcaatga
     6361 ttgactggaa tcctagttta tgtaacaggg ctatcgctgt actgcctaca ccgccagaag
     6421 caccagtaac gacaactttt ttatcggagg tcataccttg acggattaaa gcgttcacac
     6481 acaacatagc agtaaaccct gctgtaccaa ggatcatcgc ttgacgcagc gtcatatttt
     6541 ttggtagagg aactaaccag tctcctggta ctttttgata ttggctataa ccgcctggat
     6601 gggtgacgcc aagcccaaaa ccagtagcaa gtacaagatc ttcttttgaa aaacgtggat
     6661 tgttactttg gacgacagtt ccggataaat caatccctgg agtcatcgga tatgttcgta
     6721 tcacctgacc agactcgctc attgccaatg catctttata attgacatca gaataggcaa
     6781 tttttaccaa gacttcattt tcagccaact cagtaaatgg cagatcactg attgctgtat
     6841 ggaaaacagg ttcctttatt acctgaaaag atcgaaaagc gttcattcgt gagacactcc
     6901 ttttaaaatt ttcttttatc ataccataaa gcctactctt ttattcttgt tcttccgtaa
     6961 atttagacaa aaattaggtg aaaaataaag aatcaaacaa ctagaattta ttccaaaaga
     7021 taaagaaata ttcagcaaaa aaaattttac aaagggttgc ctttttcaat aaatttcgta
     7081 tactaatacg agtggtagta aacaggaagt ttactattag aaaacttcga ttcggaggaa
     7141 attatggaaa ttggtgagaa gttaagaaat ttgcgcatcc aaaagaattt gacacaagaa
     7201 gaactaggcg aacgcacaga tttgtcaaaa gggtatattt cccagttgga acgagattta
     7261 agttcaccat caatggaaac attcttttct attcttgaag tcttaggtgt gactccagaa
     7321 gaattttttc atcaagaagc agcgaatctg caagtggttt attcaaaaga agatcatacg
     7381 gtttatttcg atgaagaaaa cgggtatgaa ttggaatggc tcgtggctga ttcgaatgaa
     7441 aaagaaatgg agcctgtctt gctgactttt gaaggtgcag gagaatataa gacgtttgaa
     7501 ccttcattat ctgaaacgtt tatttttgta ttagaagggg aattagagtt aagcttagga
     7561 gagacggtct atgtggcaaa agcaggacag tcgatctatt atcaagcgac aaaacaacat
     7621 caattaagga atcatctcaa aaaacgaaca aaagtattga ttgttgcaac gcaatcatat
     7681 ttgtaatata gggggtaaaa acgtggggaa accaatcatt tcatttgatc aagtagtgaa
     7741 acgctatgat gatgaaacag tattaaaaaa agtaagtttt gagatcgaac aaggaaaatt
     7801 ttatacactg cttggtcctt ccggctgtgg taaaacaacg atcctacgta ttatagctgg
     7861 attcaccgaa gctacagaag gggacatcta ttttgaaggg aaacggttga atgatttgcc
     7921 agctaataag cgacaagtaa atacagtctt ccaagattat gcactttttc ctcatatgaa
     7981 tgtttttgat aacgttgctt ttggattgaa gatcaagaaa atgtccaaat cagatatcga
     8041 aaagaaggta aaagatgctt tgcgtatggt ccagcttcct ggatacgaaa aacgggagat
     8101 tagtgaaatg tctggtggtc aaagacagcg tgtagcgatt gcacgagcaa ttgtaaatga
     8161 accgaaagta ttgctattag atgaaccgtt atcggcgctt gatttgaaac tacgtacaga
     8221 tatgcagtat gaactgcggg atctgcaaca acgattagga atcacgttta tttttgttac
     8281 tcatgaccaa gaagaagcgt tggcaatgag tgatgagatt tttgtcatga ataaagggaa
     8341 aatcgtccaa agtggtacac ccgtagatat ttatgatgag ccaatcaatc atttcgttgc
     8401 tgattttgtt ggggagagca atatcgtgga cggtgtaatg atcgaagata atctagttga
     8461 gtttgttggt aagcaatttg aatgtgtcga tggcgggatg cgtctaaatg aaccagttga
     8521 agttgtttta cgcccagagg atttgacgat cacgacacca gataaaggaa aactagtcgt
     8581 aacggtcgat actcagctgt ttcgtggtgt ccattatgaa atcatctgtt atgatgaaca
     8641 gcaaaatgaa tggatggtcc attcaacgaa aaaagctaaa gaaggaagca aagtaggatt
     8701 ggcctttgag ccagaagata tccatgtcat gcgtttcaac gagtctgaag aagaattcga
     8761 tgcacgtctt gacagctacg aagaataggg gggacaagaa tgaaaacaat gcgcaggatc
     8821 tattccgtcc cttatatttt gtggctcggt ttattcgtga tcgcgcctgt attaatgatc
     8881 atttatcaat ctttttttga tatgaatggg caattcacgc tgaataatta tctatcttat
     8941 tttacgtcgg ggacatcgct ttctatgacg atcaattctg tatggtatgc atttttgatc
     9001 acgtttttca cgctgatcat cagttacccg actgcttatt ttttaacaaa actgaagcac
     9061 aagcaattat ggctgatgct gattattttg cctacatggg tgaatctgct gcttaaagct
     9121 tacgcattta ttgggatttt cagtgtgcac ggcagcgtga atcatttctt tgattttatc
     9181 gggatcgggc cgaaacagat attattcaca gacttcagtt ttctgttcgt ggcaacgtat
     9241 atcgagattc catttatgat tatgccaatt ttcaatgcat tggaagagat gaatccttct
     9301 ttgatcagtg ctagtagaga tttaggcgcg aatagctttg agaccttccg acgagtgatt
     9361 tttccgttat cattaaatgg tgtgaaaagt ggtgtccaag cagtatttat tccttctctt
     9421 tctttattca tgctgactcg tctgattggc ggaaatcggg tgatcacttt aggaacggct
     9481 atcgaacagc atttcttggt tacacaaaac tgggggatgg gttctacaat cggtgtgatt
     9541 ttaatcattg ctatgttcat cgtgatgctc ctgacaggcg agaagaaaaa aggaggtcgc
     9601 tcataaatga aaaaatttaa atggtcgtat ctttatttag ggatcgtctt tttattctta
     9661 tatgcaccga tcttctatct gattttttat tccttcaatg aaggaggaac gatgaacagc
     9721 tttacaggat ttacttggga aaattatgaa gctgtttttg aagatacacg tttgatcatt
     9781 atcgtattga atacgttcat gctggctttc ttatctgcat tgatcgccac gatcatcggg
     9841 acatttgggg ctatgggaat ctattacacg aaaaaacgac gtgcacggac agcgttgttg
     9901 agcatgaata acatcttatt agtctctcct gatgttatta tcggtgctag tttcttgatt
     9961 ttctttacac tactaggatt cggattaggt tttcagagtg tattgctttc ccatattgct
    10021 ttcagcattc caatcgtcgt cttgatggtc ttgccaaaat tgcaggaaat gaacgattca
    10081 atggtcgatg cggctagaga ccttggtgct aataatttcc aagtagtcaa aaatatcatt
    10141 ttgccttatc tttctccagg aatcatagct ggatatttta tggcatttac ctattctctt
    10201 gatgattttg cggttacatt tttcgtcaca ggaaatggct ttacgacgct ctcagtagag
    10261 atctattctc gtgcaagaca aggaatcagt ttagaaatca atgcgctaag tgcgttagtt
    10321 ttcttgttct ccatgatatt ggtcattgga tactacttta ttagtaaaga aaaccgtcca
    10381 aaacggctga agaaaaacag aagagtacgc gagggggtgg cacggctgcg atgaaaaaat
    10441 tacaatctct gtttttaggt attctcatca ttattgcggt gctgctgctt ggtgttcgtc
    10501 aacttgaaaa aacaagtggc atgagtggag caaaggtact taccatctat aactggggag
    10561 attatatcga tcctagtttg atcacgaaat ttgaaaaaga atatggatac aaagtgaatt
    10621 atgaaacatt tgattctaat gaagcgatgt tcacaaaaat ccagcaaggt gggacaaact
    10681 acgacatcgc tataccaagt gaatatatga tccaaaaaat gatcaaagaa aaactagtac
    10741 ttccattaga tcattcgaag atcaaaggat taaataatat tgatccacga tttttagact
    10801 tggattttga tccagataat cagtattcga ttccatattt ttggggaact ttagggatcg
    10861 tatataacga taaattcttt gatgcaaatc aaattaagca ttgggatgat ttgtggaagc
    10921 cggaattaaa agacagtttg atgctgattg acggtgcacg agaagttatg gggctttctt
    10981 tgaatagttt aggctattct ttgaatagta agaatatggc acagctgaca gaagcagcaa
    11041 ataaattgaa tcatttaaca ccaaatgtca aagcaatcgt ggcagatgag atcaaaatgt
    11101 atatgatcaa tgaagaagcc tccgtggcag tgacattttc tggcgaagct gccgatatga
    11161 tgtgggaaaa tgaacattta cattatgtga tcccaccaga aggatccaat ctttggtttg
    11221 ataatatcgt tatgccaaaa accgtgaaaa ataaagaagg tgcctatgat ttcatcaact
    11281 ttatgctaga accggaaaat gcggcacaaa atgcagagta tattggttat tctacaccaa
    11341 atgaagaagc aaaagcgtta ttgccaaaag acatttcgtc ggacgaacaa ttctatccat
    11401 ctgatgacac gatctcccat cttgaagtct acaaagatct aggatcgaaa tacctaggca
    11461 tctataatga cctattctta gaattcaaga tgtataggag ataatggcaa aactcagtaa
    11521 gaatggggac ttatcaacgt tctaaagagc taaaaatcgt cctttttcta tctgagtttt
    11581 ccaatcttct accaaaagcg gatgaaacgc cgcttttttt gtgttatttt attttttcta
    11641 ccacgttttt ctaccagaga aaagtggaca aaaccattgt aaaatagggc ccgagacggg
    11701 ctagtaaatc taagattgaa aaagttacag aaggataaag taattggaaa ctatgcaaat
    11761 atacttaacc cttctgtaat ctattaataa aactaatata tgaatccagt tcaatatttg
    11821 tagctatgaa aaaacataaa aatcatatta gataaaaact aaattggtag ataaattatt
    11881 ttgtcagata tctgaggcaa atattcgact atttgtgttt caaagtaaaa attggaatac
    11941 aaatatagaa tagacatatt gcagccgata gtttattatg cttttagaca cattaaactg
    12001 gaggaaaaaa tgaaaaagag cgctaaagat cgagtttttg atgagctgat acgactaaca
    12061 gggaatatgt cttctgtcac tgccgagaaa atttcgaaga atctaggtat ctctcgtcag
    12121 aatgccagcc attatttgac gagattagtg gaagataaaa aggtcgagaa attaccggga
    12181 aagcctgttt tgtggaagcc tttagatgaa tatgcggttg tagataatac ggagcaaata
    12241 aacgaagcct ttcattctgt agttggtcat gacggaagtc tgagagaggt cattcaaaaa
    12301 tgtatagccg ctgtcaaata tccgcctaac ggactcagtg tattaataaa tggagccacg
    12361 ggtgttggaa aaagtttttt agccacaaaa atttttgaat acgctatcca tgagcaaatt
    12421 attgaaaaag atgcaccatt tgctatctta aactgtgccg attatgcgga caatcccgaa
    12481 ctgctttcgg caacactgtt tggatacaag aagggggcct ttacgggggc tgaaaaggat
    12541 accgatggtt tattggcaac ggccaacaac ggctatcttt ttctcgatga ggtccatcgc
    12601 ctatcgaaag aaaatcaaga aaagctcttt ctatttattg atactggaaa ctatcgtcca
    12661 gtcggtgaaa atgtaaattg gcattctgct aaggttcgtt ttattttcgc cacgacggaa
    12721 aaaggtgaaa attatttatt agacaccttt gatcggcgta ttcaaattag tgttatgttg
    12781 ccaacttttg aagatcgccc cattcgagaa cgattagagc tgattcaatt attttttcaa
    12841 aatgaagcgg atgttttaca aaaagatatt attgtttcaa gagaagcctt gtctttaatg
    12901 ttatctcatc cctttagtgg gaatattggt aagctgaaga atatcattaa aatcagttgt
    12961 gcggatgtgt atagtcgaac acaagaagaa ccattaacga ttgggaaaaa tgagatcttg
    13021 attcagttaa atatgctgga atccgaagta gaaagcttgc cgattgctag tttattgata
    13081 aagaaaaatc aaaagataaa aacggatcga atcaaaccgt ttgattatga ttcgattttg
    13141 gaaaaaatta ctcagctgat aaatgaaggt aatttcaatg aaaa
//
LOCUS       DAPBCF010000066        13146 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.068, whole genome shotgun sequence.
ACCESSION   DAPBCF010000066 DAPBCF010000000
VERSION     DAPBCF010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.068"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(77..149)
                     /locus_tag="RD508_002409"
     tRNA            complement(77..149)
                     /locus_tag="RD508_002409"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="RD508_002410"
     CDS             530..1099
                     /locus_tag="RD508_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HDT7736943.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="RD508_002411"
     CDS             1086..1946
                     /locus_tag="RD508_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7736944.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="RD508_002412"
     CDS             2136..2840
                     /locus_tag="RD508_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7736945.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="RD508_002413"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="RD508_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HDT7736946.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="RD508_002414"
     CDS             4677..5993
                     /locus_tag="RD508_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736947.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="RD508_002415"
     CDS             5994..6863
                     /locus_tag="RD508_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HDT7736948.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="RD508_002416"
     CDS             6918..7727
                     /locus_tag="RD508_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDT7736949.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="RD508_002417"
     CDS             complement(7830..8459)
                     /locus_tag="RD508_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HDT7736950.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="RD508_002418"
     CDS             8629..9921
                     /locus_tag="RD508_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7736951.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="RD508_002419"
     CDS             complement(9997..10659)
                     /locus_tag="RD508_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDT7736952.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="RD508_002420"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="RD508_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDT7736953.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="RD508_002421"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="RD508_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDT7736954.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4369 a         2265 c         2833 g         3679 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt tttgtgtgta
    13081 attataatga aaatagttat ttttaatagt tataatattt tatctattaa aagtaaatat
    13141 ccattc
//
LOCUS       DAPBCF010000067        11897 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.069, whole genome shotgun sequence.
ACCESSION   DAPBCF010000067 DAPBCF010000000
VERSION     DAPBCF010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.069"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            747..2624
                     /gene="ltrA"
                     /locus_tag="RD508_002422"
     CDS             747..2624
                     /gene="ltrA"
                     /locus_tag="RD508_002422"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDT7736955.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            2755..3132
                     /locus_tag="RD508_002423"
                     /pseudo
     CDS             2755..3132
                     /locus_tag="RD508_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            3132..4337
                     /locus_tag="RD508_002424"
     CDS             3132..4337
                     /locus_tag="RD508_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDT7736956.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTEHLHLGFTRMDWRQAQGHAFTDDGTWIDP
                     LPFLNSSKK"
     gene            4353..4997
                     /locus_tag="RD508_002425"
     CDS             4353..4997
                     /locus_tag="RD508_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736957.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTFKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            5008..5814
                     /locus_tag="RD508_002426"
     CDS             5008..5814
                     /locus_tag="RD508_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736958.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLSHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDHVKDEDYEQHAINYKVKGYKKEQKAAQKQIESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKENI"
     gene            5837..6067
                     /locus_tag="RD508_002427"
     CDS             5837..6067
                     /locus_tag="RD508_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736959.1"
                     /translation="MKRANLVGKDTFAEQKVLIKAYLKVVKAKEICQEVNLSNTTISE
                     LKNGRKSLDTLKFRSFEALYIAAKKYFTAERK"
     gene            6331..7203
                     /locus_tag="RD508_002428"
     CDS             6331..7203
                     /locus_tag="RD508_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736960.1"
                     /translation="MKSSDWMEHTWLPLKRNSKRKEFWILQLWPLGKLCSYLARFILD
                     LIIYSIVVFGTAYYLLNDPNRIAASDIFTVLMTLIFVMLFTIFTQIAMQFTRQKLTAG
                     KLFKSLFDLIIVNAILATLIKQIEQFGRTTKGLKEFLMTFVHFVNGYMYLFEVGIILF
                     LFGYISTKLIKRSIEKEIEIDLIPTLFGYEYYVDFGRYDELINTGIVHTSIYEATVKG
                     IRTTLKDGQESKAIDRRKEIYNFYEVEASLRYGIGKLSLDGRNIPQNKPYIGWKSDAL
                     EVSKKLSMEEDELQ"
     gene            7200..8597
                     /locus_tag="RD508_002429"
     CDS             7200..8597
                     /locus_tag="RD508_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfJ domain-containing protein"
                     /protein_id="HDT7736961.1"
                     /translation="MSSINLNHLFEDISNHFQQFSIEDNDELMGLFQIEKEYDYLTFI
                     CREGRIIDPKESKIISHLRRFKNYISKNKETISEIKFDGTTNLEYLVRVTYQRNRRLI
                     EDDQGVLICAGEEYDSLKFTQLKFESIGRSIYFESRPFYIRYNDFQHLFLQDEPNGLT
                     ILERRGKKQITLSYERPLTFMDGSCESIFQKINPFIKEMMKEKDSLPFTWAEIIEAKN
                     KYELLCKKYPSKKFTKKVNKYPLRHTYALIKLKPRVTRKQFRRIEAAIEQEDIDVFPS
                     ERFDFIRKNSREFVKSLLISYVQNCILPSFATIILSDLMDMSFYLNQKLEFNFKTERG
                     LLRQHNQIVEEYNLKQAKRLKTFKLKQHGKYRLLVKHLQNHPHFNLIKTNKELFMEGS
                     TMHHCVYNYLEKIQRGGSTIWKYERQKHRYTVEIEKRKYGNYEVVQCYGKYDSLPDKQ
                     ELDEIKKVVRAIPYK"
     gene            8863..9138
                     /locus_tag="RD508_002430"
     CDS             8863..9138
                     /locus_tag="RD508_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736962.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            9180..9602
                     /locus_tag="RD508_002431"
     CDS             9180..9602
                     /locus_tag="RD508_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736963.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKSNKTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            9621..11213
                     /locus_tag="RD508_002432"
     CDS             9621..11213
                     /locus_tag="RD508_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736964.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPDE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKSLKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIESMD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            11234..11569
                     /locus_tag="RD508_002433"
     CDS             11234..11569
                     /locus_tag="RD508_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736965.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            11710..>11897
                     /locus_tag="RD508_002434"
     CDS             11710..>11897
                     /locus_tag="RD508_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7736966.1"
                     /translation="MAHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYRSGDI
                     LALNLITKTFVDAVENYP"
BASE COUNT         4512 a         1770 c         2416 g         3199 t
ORIGIN      
        1 agtgccataa tggtgcgacc tgttctgcag tgaaaagctg tgggttgcaa gtagtctaaa
       61 aactattgta ataactctta taacgagaag tcaaatgagt gggtaacgcc acaaagggct
      121 tccactgata ctccgacatg caacaagtag tttatgcaga ccaacgttgt gtgaagctcg
      181 gtgaagtcgg ctgaaggata ccgtaaggta aaagaaatag tgaataccac gaaagttctt
      241 tagaggtaaa gggtgtatcc gataagtcgg gtgtccaaaa aaacttaata tggtgagtat
      301 gtacaaacgt actgacgaac tagcgaatgt actgtccgaa aggcatagct cctagaaatg
      361 ggagagacag tgagcaaaaa atcactcatt gtgctaactt gtggttgagt aaaagtcgtt
      421 gttatgaaag accatgctgc gttacaggcg taggagaagt tagggggcaa aagctagcat
      481 ctaagttaag gcatgtggat agatataagg gaacagggga agccatcaac atggagagtg
      541 catactcgat gaagtggtag taagaaatat gtgaatgaca aataacttac tttagtgatg
      601 gtgaaagtag agtcacgact gatgaaggtt ctgtaatgga actggaggaa caggctcgat
      661 tcgtctgtaa aagtcatgaa acccgttcaa ccatgggatt ctcgtatgac taaaaaggtc
      721 acgagccaat tggagcgtga taaaccatga caaaagaaac aagtccaaaa gataggaagt
      781 tgcggcatgc agaatattat ggcatgacgg aaatcttcga taagatatac tccaaaagtt
      841 tgaagggaga taatttcaag aatctaatgc agattatcat ttctgataac aacattgtcc
      901 tagcatatcg taatatcaag agaaatcacg gtagtgtgac aagaggagaa gatggagtaa
      961 cgattaaaga tattgaaaat ctcaaccgta atgaattcgt agaaattgtt aggaagcgat
     1021 tcgcacatta taaccctcgg aaagtaaggc gtgtagaaat tcctaaatat aatggtaaat
     1081 taagaccgtt gggtattcca tcaatatggg atagaatcgc gcagcaatgc atcttacaag
     1141 tattagaacc aatatgtgaa gcaaaattca ataatcacag ctatggtttc cgcccaaata
     1201 gatcagcaga acacgcaata gcagattgta tggcccgaat gaatcaaagt cacatggaat
     1261 atgtggtaga tgtagatatc aaaggtttct tcgacgaagt caatcatact aaactcatga
     1321 gacaaatctg gtctatgggt atacgagaca aacagcttct cttaatcatt aggaaaatgt
     1381 taagagcacc cgtagtactt ccaaatggga agttgatata cccaacaaaa ggaacaccac
     1441 aaggcggaat acttagccca ttacttgcga acatcaatct caacgaattt gactggtgga
     1501 tagcaaatca gtgggaggaa aaagatgcca aagagctaaa acatcatttt aggaaaaatg
     1561 gagcttggga taaaggtaat atctatcaca agctcagaaa gagtacaact ctaaaagaaa
     1621 tatacctagt gagatacgca gatgatttta aaattttctg tagaaattat aatgaagcga
     1681 aaaaagtttt ctatgcaact aaaatgtggt tacaggagcg tctaaagtta ccaatatctg
     1741 aagaaaagtc aaaaatcaca aatctttcaa aagaagaaag tgaattttta ggctttacga
     1801 tgaaattagt gaccaaaggt aacaaaaagg ttgttaatac gcatataggt acaaaagcac
     1861 aaagcatgat taaagtgaaa ctaaaaaaac aaatcaaacg aattcaaaaa agtcctaata
     1921 gcaaagatac ctttatctat attggagtct ataacagtat ggttattggg attcataatt
     1981 acttcaaaat tgcgactcat tgtagtgtag caatgcgaaa aattgcaaga gaactcagac
     2041 caagttttga aatacgacta cgagaacaag gaatctcaaa agaaggacaa tacggaaagt
     2101 acgaaggata caagccttac ctacggtcag gacaaatacg atatataaga gggtttccaa
     2161 tattaccagt agggtatatt caacacagac atccgatgtg taaaaaaaga aatattaata
     2221 aatacaccga agaaggtagg gaagccattc ataagaagca acaaaccgta gaagaatgga
     2281 agatatcgtg gttgtgtagc aatccagtgc ttagtaagag agcaacgatt gaatttgcgg
     2341 acaatcgaat ttcaaaattc atcgctcaaa agggaagatg tgcagtaaca ggtgaggagc
     2401 ttatcttatc tgaaatgcat tgtcatcata ttatccctta tcatgaaagc aaaagtgata
     2461 gctatgaaaa cctagtgatt gttactgagg aggttcatcg ggtaatacac gctacacaaa
     2521 gtgaaacgat tgaggaactt ctaaaatatc taaaattaaa tccaaaacaa aaagaaaaac
     2581 tcaatgagtt gagattaaaa gttggtaacg aagaaatatc ttaataaata tttgtaggac
     2641 gggaaaacag aatgtctttt atagacgagg gaacgccgta tgcggtgaaa gtcgcacgta
     2701 cggtgtggac tgggggaaaa gacggagata atatcaaact cttacctatc agtatcgatt
     2761 aatccagatt ttattgaaac ggtaaattat gtcacaaact ttcaacgaga aatgcgtaaa
     2821 gtagaagcaa tgactgtttt agctacacaa tccccacaag aaatggtgcc agaaaatatg
     2881 tcttctgata acttctcgaa actgaagaaa gtctttgaat tttcttctac gaagatcttt
     2941 atgcgtatgg atgaatctat tttacgtcat atagaaggat tagttggtaa atcaatgaca
     3001 aactcagaat tagaatccat tcctcaacaa aatcaaggag acgctgtgat caattttggc
     3061 tcaaaagaaa ccattcgtgt tcattttagt ccgaacaaac gtcaattaaa attgtttgat
     3121 ggaggaaaat aatggaaaac caaaatgaaa gtttaatcaa gcagtatgtt aagcgtcgtg
     3181 caaagcgacg cttatttttg tggttgtttg gtacttctgc aggtttgatt actattttga
     3241 ttactgtgtt cgtgaccctt tttctaatac ttgcggcggg ttcgattgat aattctgatt
     3301 cggattcaag tagtggtggc gaagctttta caggagaata ttcggaagga ttacccattt
     3361 ataaagaaat caaaggaaga ggcccttttt ctgatgagat tgcgcaatat gctgtaggtg
     3421 cagcagtcaa atataaatta ttaccaagtg tgatcctttc gcaatacggg tatgaatcag
     3481 cgtttggtac gtcggcgtct gcaagaaatg atctcaatta ttttgggatt acttggttcg
     3541 atggctgttt atttcccaaa ggaactgcgc gtggaattgg tggcattgaa ggtggctggt
     3601 acatgaagtt tcccaactca aaagctgcat tttcctatta cggatttatg gtagccacac
     3661 aatccaattt taatgcttgt gtcggaaata aaagccctgg tgcaagctta ttgatcttag
     3721 gacgaggcgg ttatgccgct gcaggaatta cggaagatag tccgtattat acaggttgta
     3781 tgtcaattat cacttctaat aaattaaccg aatatgatga attcgccatc aaacattggg
     3841 gtgaaggtgg caataacaac ggcacgatca ctggtgaatg gacgaatcca ttccctggca
     3901 gcagtttaga taaaagttcc tttagcggtg gtcaattatt tggaacgaat ccagggggag
     3961 agttccgacc gaatggtttc catgacggat tagattttgg ttcagtcgat catccaggaa
     4021 gtgaaattca cgcggtgcat ggaggaaaag tcgtgtacgt tggcaatcct ggtatttcag
     4081 gtttaggtgc atgtgtgatc gtgattaatt acgacggttt gaatatggtg tatcaagaat
     4141 ttgcgaatag tacaggaaat tctcgtgtga aggttggaga tcaagtgaaa gttggtcaag
     4201 taatcgggat acgagataca gaacacttgc atttaggttt cactcgaatg gattggcgtc
     4261 aagcacaagg acacgcattc acagatgatg gtacatggat cgatccatta ccatttttga
     4321 atagcagcaa aaaatagatc aggagaaaaa atatggaaaa taaaacttta aaaatcgtct
     4381 taacagctgc aattagcgtt agtttaatcg gcaatatcgc gttgttttgg cagcttaaag
     4441 aagaacaaga gacaaatacc tttaaaattg aagaagtggc taaaaacgcg tctgagaagc
     4501 tcaaaaaaaa ttcctctgag gcacaggcga agatcgacaa gttaaatcaa accatcaatg
     4561 agaaaaacca agaaatcgat cagctgaagc aacaagatgg cacaaaagca aaagaggaag
     4621 tcactgaagc acaaagaaag acggcagaag agttcgggca attggccatt gataaatcat
     4681 taagcagaaa tgaattaacg gaaaaactaa aagatgtcgc aacccaagaa gtgatcgaca
     4741 aattaagtcc tgcagacgat gatcaccaac atgatgatta cggaagttac tcctttacat
     4801 taggtgacgt gcaaacttac gctcaaacaa gcagtgtaaa agaggaacaa aactttgtgg
     4861 tatttgttga ttatacaatt ggcaatcctc aattcaaaga tgtcaaacca caaaaaataa
     4921 aaggtggatt aactgtcact gaaaaacagg tagatggtca atggaaagtc acagacttta
     4981 gttatttcac tcgttaggag gaagaaaatg agtaagaaaa aaggagcaag acaacgtttt
     5041 aaaaaacgaa aaagttatct tagatggctg ggaatcttta tgattctcgg ctttttgatt
     5101 cttgctagtc cgatttacac gcataagaag gtagacatac cagatgaagt aagcacgaac
     5161 gcctttttaa acacgaagga actgacgatg gtttcaaaag aaaaaggagc gaaccagcaa
     5221 ttagtttttg aatttgcgat cgacgatgaa gatcagagct tattaaaaga actagctaat
     5281 cttaattatc gtgtagaagt aaagacagct aaaggggatt atcaagcaat aaaagccaaa
     5341 gtgatcaagg tgtctgatga ttattttgta gtgaagctat cgcatgtacc agaagaatat
     5401 attgctatgc gattaaccat tatccctgaa aaaattgatc caaaggtgga tatgcaagaa
     5461 ccgcaagatc tgatttatta cgttcacgaa gataaggtca aagatcacgt gaaagacgaa
     5521 gattatgaac aacatgcgat caattacaaa gtgaaaggat acaagaaaga acaaaaagca
     5581 gcacaaaaac aaattgaatc tttccaagca accatagatt tgaatgaaga attagtgaag
     5641 aaactaaaag atcagttgcc ttatcaagtt gcagacgatc aggaaaatac tgaaaataag
     5701 attaatagtt accagcaaga aattgaaaca tcgaaaacgc aaatgaaaga tcaagaagag
     5761 atcattcaaa aacttcaaga aaaaattgat cgtatgacaa aagaaaatat ttagaagaat
     5821 aggtggagta aaagaaatga agcgagcaaa cttggtcggc aaagatactt tcgctgagca
     5881 gaaagtattg attaaagcct atctcaaagt tgtaaaagct aaagaaatat gtcaagaagt
     5941 gaatttatct aacacaacaa tatctgagtt gaagaatggt agaaagagtt tagatacctt
     6001 aaaattcaga tcatttgaag ctctatatat agctgcaaaa aaatatttta cggctgaaag
     6061 aaaataaaaa caggaggatt ttatgtgaaa aaagtatatc aaaaatgttt atggatcagc
     6121 tatatcaccg taggtatagc tgtttttttc tttagtttag ccgttatcgt cggtacaatt
     6181 tttctttggt ttatcaataa agatttatca tttaattggt tcatgagtct attgtcgttc
     6241 attatgttga tctttttatg tttagaaatc cgcgaattca tgccttctca ttggcaagat
     6301 aagaggaaag agtttagaga agaaatcgaa atgaaatcga gcgactggat ggaacatact
     6361 tggttaccat tgaaaagaaa tagcaagcga aaagaatttt ggattctaca attatggcca
     6421 ttaggtaaac tttgtagcta tttggctcgt tttatacttg atttaatcat ttactcgatt
     6481 gtagtatttg gaacggctta ttacttatta aatgatccca ataggattgc agcatcagac
     6541 atttttacag tgctaatgac gttgattttt gtcatgctat ttactatttt cactcaaata
     6601 gccatgcaat ttaccaggca aaaattaaca gcaggaaaac ttttcaaaag tctattcgat
     6661 ttaattattg taaatgcaat tctagcaact ttaataaaac aaatcgaaca atttggaaga
     6721 acaacaaaag gactgaagga atttttaatg acgtttgttc actttgtaaa tgggtacatg
     6781 tatttgtttg aagtgggtat tattctcttt ttattcgggt atatatccac gaaacttatt
     6841 aaacgttcaa ttgaaaaaga aattgagatt gacctgattc cgacactttt tggttatgag
     6901 tactatgttg attttggaag atatgacgaa ttgatcaata caggtattgt tcacacgagt
     6961 atctatgaag cgaccgttaa gggcatcaga actacgttaa aagatggcca ggagtcgaaa
     7021 gcaattgacc gaagaaaaga gatctacaat ttttatgaag tcgaagcaag tctaagatat
     7081 ggtattggaa aattgtcgtt agatggaaga aatattccac aaaacaaacc atacattggc
     7141 tggaaaagtg atgctttaga agtatctaaa aagctttcta tggaagaaga tgagcttcaa
     7201 tgagttcgat caatttgaac catttatttg aagatatcag taatcatttt caacaatttt
     7261 caattgaaga taatgatgaa ttgatgggat tattccaaat agaaaaagaa tacgactatt
     7321 tgacatttat ttgtcgtgaa ggaagaatca ttgatcccaa agaatcaaaa atcatttccc
     7381 atttaagacg attcaaaaat tatatcagta aaaataaaga aactatttca gaaataaaat
     7441 ttgacggaac aacaaactta gaatatttag taagagtcac ctatcaaaga aaccgccgac
     7501 tgattgaaga tgatcaggga gttttaatat gtgctggtga agaatacgat agtctcaaat
     7561 ttactcagtt aaaatttgaa agtattggtc gttctattta ttttgagtca cgaccatttt
     7621 atatccgata taatgatttt caacatttgt ttttacaaga tgaaccaaat ggattaacca
     7681 ttctagaacg aagagggaag aaacaaatta cattatccta cgagagaccc ctcacattca
     7741 tggatggttc atgtgaatct atttttcaaa aaatcaatcc gtttattaaa gaaatgatga
     7801 aagaaaaaga ttcattacct ttcacttggg ccgagattat agaagcaaaa aataaatatg
     7861 aattattgtg taagaagtat ccgtcaaaaa aatttactaa gaaggtaaat aaatatcctc
     7921 tacgtcatac ttatgcgctg attaagttaa aaccaagagt aaccagaaaa cagtttagaa
     7981 gaatagaagc tgcgatcgaa caggaagaca ttgatgtttt tccttcagaa agatttgatt
     8041 ttataaggaa gaacagccgt gaattcgtaa aatctttatt aattagttat gttcaaaact
     8101 gtattttacc aagttttgca acgattattc tatctgattt aatggacatg agtttttatt
     8161 taaatcagaa actagaattt aattttaaaa cagaacgagg attattaaga cagcataatc
     8221 aaattgttga agaatataat ttgaaacaag ctaaaagatt aaagacattc aaattaaaac
     8281 aacatggtaa atacagattg cttgtcaaac atttacaaaa tcatcctcac tttaatttga
     8341 ttaaaacaaa taaagaactc tttatggaag gatcaactat gcaccattgt gtatataatt
     8401 acttagaaaa aatacaacga ggtggttcaa ctatttggaa atatgaacgg cagaagcatc
     8461 gttatacagt tgaaatagag aaaagaaagt atggcaatta tgaagtggta cagtgctatg
     8521 gaaaatacga ttcattgcca gataaacaag aacttgatga gatcaaaaag gttgttagag
     8581 ctattccgta caaatgatat cacctcaagt tcttcttaat ttttaaagag cataaggaaa
     8641 cgtgatatca ctttctcacg aaaggtgtta ggtaggctgt gcctaccacg tttctaagaa
     8701 agataaatga tatcaaaatt ttggatttgt gtgtagattt gtgggtagga tgaaagcgaa
     8761 tgtgggcagt aaaataagcg tttgtgtgta gcaaaatcaa aaaatgtgta gggatatgtg
     8821 tagctacaca tatccctaca cataataaat ttggaggaaa atatggactt attaattaga
     8881 aatattgaag aaaagtatat taataaaatt gacaaacgtt gtgaagaact tacggtcaag
     8941 actggcaaaa aatggagtcg aaatcaatac ctaaaagttt tgatcgaaaa tgattttgat
     9001 cacgctcttc tgaattataa aaaagaccaa tttgatcggt tgttagaaaa atttgtggat
     9061 attcaaactt ataatacgaa aactttagaa gaatatattg caacaaataa tcaattaatt
     9121 ggtttgttaa ttgaataata aaaatagtat tgtgaattta taaaaggagg aaatcaattt
     9181 tggcaaaagc aacaagaaaa catgtatatc tttacgatat gcatatcgaa gtacttgatg
     9241 aaataatttc tactcatgaa gatatatcta attatagtga agcagtcaga catttgtgta
     9301 tgatgtatga tccaaaaatc gaagaaaaaa taaatccaat tcaaattaaa ttgaatgcaa
     9361 tgggaaaaga aatttctatt ttaaccgaaa tggtttcaga gtttgcggat cttcatttga
     9421 aagatacagg aatactaatt ggtacaaatt caacggttta ccaagaagca aaagaacgtg
     9481 tggaaggaaa aattaaatcc aataaaacca aaaaatattc ccctcagttg aagaaacctg
     9541 tgaatgaatc tgttcatgct agagtagatc catttgatcc aacgaagatt ctaaaaagat
     9601 aaaagtagaa gggaaacatg atgaataaat cgcctgcagt cattctcact tgtcaattta
     9661 ccttgcccaa taaaaaatct ttttcaacat acattgatta tatgacaaga gaaaaagcgc
     9721 tggaagaaaa ggaacgacgc acgccggacg aagaacagga actgcaacga atcaagaatg
     9781 ctttagagga tttttatatt cctgaaggag aaactttttc ggagagtaag acagataaag
     9841 aattcagtga aacgtcgaat gaagctcaat cgttgatgga acatggaatc aattttgaca
     9901 agttagagga acaagatttt accaaatatc tttcttatat gacccgtcac tatgcgttag
     9961 aacaaaagaa agaactgacg caaagggaac aaaaagaata ccaacggttg aaccaagcaa
    10021 tgaaaaaata tcaaacagag ccacataaaa aagcttcagg aaatcttcct ggagtttttt
    10081 ctatggcttc agacgaagtg aaaggaagtg atctgaagga gatcaaacaa atcttccaaa
    10141 gagggcaaca aaaaggctca atcatttatc aagatgttgt ctctcacgac aattcgtatc
    10201 ttgaaaaaat gggcttgtac gatcccaaaa cagatacctt agatgaagaa ggattaaaag
    10261 cagctggaag aaaaatgatg gagacattat tcgagaaaga acaattgaat gaaacaggtt
    10321 actggatggc aacgattcac cgtaacacta agcatatcca tattcatttt gcagttgttg
    10381 aaaaagaaaa tacgcgtaaa ccttacacgg aggttgaaaa tggtgtgagt tatatcgtac
    10441 cgaaaggtaa gagaagacaa gcaacattag acgcaatgaa gaccaattat gtacatgagt
    10501 tagaacgttt ttcttatgaa aaggatcgaa tgattggtat ggagaaacga aatttattga
    10561 cgcggaaaag tgatttgcgt aacaccttaa caaaagtggt aaaagagcca gcgcgttacg
    10621 atcgacacgc aatgaactta ttaaatgaag tatataaaac cctacctgac aaacgttcgg
    10681 aatggcatta tggggatgaa aaacgaacca aactttcacc atacacaaga gagaaactcg
    10741 atgagttaac caaatatgtg ttaacaaaag aacctgaata tcaagaatat atacagattt
    10801 caaaatcatt gaaagaagaa gcaaaaagtc tttatgggga aagcaagaga gaatcaaagg
    10861 atgcagaaaa aaatgctctc tttgatttga agaagcgcac aggaaatgcc attctaacag
    10921 aactgaagaa acaggatagt caaataaaac ctttaataga aagtatggat cagatgcaat
    10981 ctatttacaa tgaacgatcc tttcgaacgc ttaaacagtt accaacgaat gaatacaaat
    11041 atagttacga agaattcatg aagcgcagga aacaattcca acaaagagtt gtcacgcaac
    11101 ggagtttgcg tcaattaaat cgaacgatta atgcccatga agaaaaatac cacgcaagta
    11161 aagcctacga agagcaacaa cgaagaattc aaatggaaca agaaagacag taaagacagt
    11221 aggaggaata gcaatgaaac aatatttaga tcaatggaaa gtcatagaag gatcattaag
    11281 agaagaacga atcgaacaac ttcccgattg tttagaaaaa gagcatttgt ttcagataag
    11341 agaaatgttg agaaacgaac agtttgatcc aaatcaattt ttagtcgttg agtacccagc
    11401 tactggtgtg tactgttgta atcatgtgaa gggtgaaaaa tattttatca ttcaagaata
    11461 tgagggcaag ttagcgcctt attatactac ttgggaaatg aatgaagagg ggatcaataa
    11521 cttcccgtgt aaaagcattg aagagtctat ttcactcaca gaatgttagt tgttaagtga
    11581 ataaaagaag taaaagagtc ctgaacataa tttgtccagg actctttttt tcaatgaatt
    11641 gttttccgcc aattcattga gtggtgcgat ttccgtctac attatatcaa aagaaaggag
    11701 gaaaaagaaa tggctcattc aacgattgga gttgttgttg aaaaaagcag agacaatctc
    11761 gtttttgtga cagaaattca aacaggtaga tcttttgtcg tcacagacaa agcggcaaaa
    11821 gcttatcgaa gtggcgatat tttagcgtta aatctgatta caaaaacgtt cgttgatgca
    11881 gtagaaaatt atccatt
//
LOCUS       DAPBCF010000068        11750 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.070, whole genome shotgun sequence.
ACCESSION   DAPBCF010000068 DAPBCF010000000
VERSION     DAPBCF010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11750
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.070"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..141)
                     /locus_tag="RD508_002435"
     CDS             complement(<1..141)
                     /locus_tag="RD508_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7736967.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQ"
     gene            complement(315..2390)
                     /locus_tag="RD508_002436"
     CDS             complement(315..2390)
                     /locus_tag="RD508_002436"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDT7736968.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDIKTDRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKDHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEV
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2392..3309)
                     /gene="glyQ"
                     /locus_tag="RD508_002437"
     CDS             complement(2392..3309)
                     /gene="glyQ"
                     /locus_tag="RD508_002437"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDT7736969.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRF
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARSVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(3693..4505)
                     /gene="recO"
                     /locus_tag="RD508_002438"
     CDS             complement(3693..4505)
                     /gene="recO"
                     /locus_tag="RD508_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDT7736970.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFLSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHAYPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKMPEKNMPEKEIPEKEE"
     gene            complement(4648..5547)
                     /gene="era"
                     /locus_tag="RD508_002439"
     CDS             complement(4648..5547)
                     /gene="era"
                     /locus_tag="RD508_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDT7736971.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYTALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5562..5957)
                     /locus_tag="RD508_002440"
     CDS             complement(5562..5957)
                     /locus_tag="RD508_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HDT7736972.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQIDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(5941..6417)
                     /gene="ybeY"
                     /locus_tag="RD508_002441"
     CDS             complement(5941..6417)
                     /gene="ybeY"
                     /locus_tag="RD508_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDT7736973.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6434..8626)
                     /locus_tag="RD508_002442"
     CDS             complement(6434..8626)
                     /locus_tag="RD508_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HDT7736974.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNTGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8650..9621)
                     /locus_tag="RD508_002443"
     CDS             complement(8650..9621)
                     /locus_tag="RD508_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDT7736975.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10326..11705
                     /gene="brnQ"
                     /locus_tag="RD508_002444"
     CDS             10326..11705
                     /gene="brnQ"
                     /locus_tag="RD508_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDT7736976.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
BASE COUNT         3177 a         2454 c         2150 g         3969 t
ORIGIN      
        1 ttgcttgaag aacagatata ctttatggat cgtttgtctt gaacgattca agcaatgggc
       61 agttttagca acagattgat tcattttgaa ataagactct attattacaa gttcatccgt
      121 tgtaagatgg gtataggtca tttgtactca ctccttataa ttctttggtc ggaactattt
      181 tgagtgtagc acaaatgact tttttagttg tctagcttaa ttttacaatc ggcgagttat
      241 ttatatttat aacaaataaa ccagagaaat agcctatttt gtgcctgttc tctggtttat
      301 ttacatatta gaaattattt tgtgatgatt tgatctaaac ttgctagtga caaagccatg
      361 gcagcaattt gacttaattg cgttaatcgg ttcttacgta ctgctggttc ttctgccatg
      421 accatcgtct gatcaaaata attttcgatc agtgggcgaa ggcttacaag ctgatcataa
      481 ttttcgttga tcgtttggtc agcaaagctt gttttcatta cctctactgc tttgtgcagt
      541 tctttctccg cttcgttttc gaacagttca gggtctactt ctgattgttt ttcaagctcc
      601 gcttttttcg ctaagttcac gacacgtgtc aaagcttcca tcgatggttt gaagtcttca
      661 tctgcaagat gctgcttgaa caattgtgct gctgcaaata cttttgtcag atctttttgt
      721 tctgcgttca aaacagcttc gatgacatca tgacggatat tcttcgttgt caataattgg
      781 cgcagacggc ctttgataaa gtcgatcacc tgttgttgtc ccgctgacaa gccaatgcca
      841 aaacgatccg tatctttact gataacttca ctaatcgttt cttgcagaac agacaaagga
      901 aaggcccatt ttttcgattc gatgattcga acgacaccat atgcttgacg gcgcaaagca
      961 tatggatcgt ttgagccact tgggatcatc ccaactgcaa agaaagaaaa gatactatct
     1021 aatttatcag caatcgctaa aacagaacct actgtagtct caggtaaatc tccttcactg
     1081 gatataggca tgtaatgttc acggatcgct gttgctacgg ctggtttctc gcctttaagc
     1141 agagcatatt tttctcccat gatcccttgt agttcaggga attctcctac catgttggtt
     1201 actagatcaa atttatagat ttcagcagcg cgttgcagat ccatcaattc ttcctcagac
     1261 agtcctactt gttcgcctat gatgcgagcg atgacttgta cccgttgcat tttctcatag
     1321 atgctaccga ttttttcatg gaaagtaaca gtttttaatt tttcaacgta ttggtcgatt
     1381 gaagctttct tgtcttcatt ataaaagaat tccgcatctt ctaaacgagc agtcaatact
     1441 ttttgattgc ctcgtaccac attttccaat tttacccgat cgccattacg agcagaaata
     1501 aaatgaggaa gcaacatacc ttgatcgttc cgtacttcga aataacgttg atgttctttc
     1561 atagaagtga ctagtacttc ttcaggaaca gatagatatt tttcttcgaa gtcgccagaa
     1621 aagacagttg gatattcgac tagattgttg acttcttcta gtaaatcttc atctagatca
     1681 atgatccagt gatctttttc tgctaattcg tttgcttgtg tgatgatcat ttcttttctt
     1741 ttttgcggtg aagcaataac aaattgttca tttaattttt cttcgtattc ttttgcatgc
     1801 gcaaatgtca catcttcgcc taagaaacga tgacctcttg aagctctgtc tgttttgata
     1861 tccaagatct caaacgggat tacttcgtca tctaacaatg ccacgatcca gtgaatagga
     1921 cggatatatt caaaatcgta ttctgcccaa tgcatcgtta ctgggaaagt gaggctttta
     1981 atgacatctg ctaaacctgt caatacttct tttgcttctt tgccgtgagt gtatttcgtt
     2041 acatagacat attccacgcc ttttaattct ctaaaagtga tagcatctgt cgtcagacct
     2101 tgtccgcgga caaatccttc cgctgctttc gtccagtttc catctgcgtc caaagcaatt
     2161 tttttggctg gtcctttgac ttcttcttca ctgtctgctt gacgttctgg aatgtttgtt
     2221 actttgattg ctaaacggcg cggtgtagaa aatgtttcaa tcgtatcata agtcaattgg
     2281 ttttcatcta aaaattttgc tgttttttct tctaattgtt tcatgcttgg tgtgacaaca
     2341 tgagcaggca tttcttccag cccaatttca agtaataagt cttttgccat cttattcagc
     2401 ctccttcacg ttttctggat ttgctgtgtt tttattcaat aaagggaatc ctaatttttc
     2461 gcgttctgcc acaaagattt tggctacaga acgagccatg ttgcggatac gggaaagata
     2521 acctgcacgc tccgttacgg atactgcacc gcgggcatct aataaattga atgtatggct
     2581 gcatttcaaa atataatcat acgctggatg aacaagattt tcatcgatac agcgtttagc
     2641 ttctttttca aaacgatcaa agttgcttag tagcaagtct tggtcgctta cttcaaaaga
     2701 atatttggaa tgttcatatt ctggttgttt gaagatctcg ccatatttca cgccatcagc
     2761 ccattctaag tcatagacac tttcaacttc ttgaatatat gaagcaagac gttctagtcc
     2821 ataagtaatc tcagaagtaa ctggtttaca aggtagtcct ccgacttgct ggaagtacgt
     2881 gaattgtgta atctccatcc catcaagcca tacttcccaa cccacaccgg cacaacccat
     2941 cgatgggttc tcccagttgt cttcaacaaa acgaatatcg tgttctaatg gatcaattcc
     3001 taaaaaacgc aagctttcta aataaagctc ttggatattt tcaggtgaag gtttcattac
     3061 gacttgaaat tgatgatgct gatacaaacg gtttgggttt tctccataac gcccgtcagc
     3121 tggtcggcgg gatggctcta cataagcagc attccatggt tccggtccga ttgcccgtaa
     3181 gaatgtatat gggctcatcg tacctgctcc tttttctgta tcataagctt gcatcagcat
     3241 gcagccgttt gatgaccaaa atttttgtaa tgttaaaatc atatcttgga cggtcaattt
     3301 tttactcatc tgttttgccc ctttcaattt ttaagcgttg ctgtcaataa gaatacagga
     3361 aagaaaacga caaaaagtcc ctatgtctga ttacagacat agggacgaat aatttcgcgg
     3421 ttccacccta cttccgaata aagattcggc agcttcattt atcgtactcg caagtgcctc
     3481 ttcaaaaatc gtttgggtcc ggcttccact ctcccgaact cgctaaacca cgtgtttttt
     3541 actgatcttg gtcaatgtac gtattcattt tgcagttttc ttgtttatat aatagatcct
     3601 ctcagtgaac gatctattta atctacggtt aataatagac ggaagtccct gtatttgtca
     3661 aatagttttg atttttttgt tgtatctttc atttattctt ctttttcagg tatctctttt
     3721 tcaggcatat ttttctctgg catctttaat acgtgtgccc aagacttcat ttgatcaatg
     3781 aactttttgc tttttagatg aataccgaca tattcatcat acaactggtc aatgaggtca
     3841 cggattgcct gcttcgtttc ttctttcaag tggattccac tgatcttatc ataagaaata
     3901 gccgaaaaca ttcgaacgaa ataaacagcg cgaggatatg catgataacg gtgttcgtcc
     3961 attggccagt gtttctcgca tatcacgccg ccatatttgg aagaatagtc aaattttcct
     4021 tttgtttccc cgcatacgac acagtgcgtc caaattggcg cgattccgaa gcgttgcagt
     4081 atttgaactt caaagatatt cgtgatgatt tctgcatcat ctccttggtc catccgctgc
     4141 agagcttgtt gcgtaaattg gaataagtgc gggtcatatt gatgatcttc gattgctgca
     4201 tctactagat ttagcaaata cgtaccataa ccgctcaaaa agatatcttc ttggatgttc
     4261 cgaaacgcat ggacgtcttt gacactgctt aaaaacgaca aaccttcact tagaaaatta
     4321 ccgatataga ctgcttcggt aaaggggagc aaagccggag ctaatggctg attttgccga
     4381 tggattcctt tgatataaaa catcattttg ccagaagatt ccgtaaagat tttgactaat
     4441 ttatcttttt ctttgtaatt acggctagat aaaatcaagc ctttcgattc tgcaagctgg
     4501 ctcatattct ccctcctaaa aaataaatct ggaaaagcag attctgccga tccagattat
     4561 ttatgttacg atctttcgct gtttttctca acgtacggat ttttatccag tttatttcta
     4621 tacctaacct ataagaagtc cagaatatca gtactcgtct tttcggtagc cgaagtcttg
     4681 cagatagact tttttgtctc gccagtcttt ttggactttg acccaaagtt ctagaaatac
     4741 tttgtctcct aaaagatttt cgatatcctt tcttgctttc gttcctactt gcttcagcat
     4801 ttttccacct ttgccgataa tgattccttt ttggctatct ctttcaacga tgatcgtggc
     4861 ctggatatgg attttatcat tctcgtttcg cttcatcgaa tcaacaacga ctgcgacaga
     4921 atgaggcact tcgtctcgtg ttaaaaacaa gactttctca cggatcaatt cagaaacgat
     4981 gaagtattca ggatgatcag tcacttgatc atctggaaaa tattgtgggc cctctggcat
     5041 ttcactgact aatacatcca ttaagcgttc gacattgttt ccttctgtag cagagatcgg
     5101 aatcacttgt gcaaaaggca tctgcgtcga ataatcttcg atgattccca gcaactcgtc
     5161 tggatggatc ttatcgattt tattgataat cagataaact ggagaatgca cgttttttag
     5221 acgttcaata ataaaatcgt ctccccggcc gcgtttttga tcagcactga tcataaataa
     5281 gactgcatcc acttctttca acgcagtgta agctgcttct accataaaat ctcctagacg
     5341 atgctttggt ttatggattc ctggtgtatc gataaaaatc agctgagctt ctggtgtagt
     5401 atatactcct tggattttat ttctagttgt ctgtgccttg tcactcataa tggcaatttt
     5461 ttgacccacg attcggttca ataatgtgga ttttcctaca ttcgggcggc cgacgattgc
     5521 gacaaaccct gatttatgtt ctggcatata cgttctcctt tttaattaaa caacaaatga
     5581 tatattttag ggacaaataa aatcaaccca atgatgacag caaaacaagc ggtcactaaa
     5641 actgctccag ctgccatatc tttgattttt ttcccaatcg gatgaaaatg aaaatccgta
     5701 aacatgtcca ctacattttc aaaaacagta ttgatgatct ctactatcca aacgagaaaa
     5761 acagctaaaa gcagccataa ccactctatc cgatcaatct ggaaaatcac gcccataaat
     5821 aaagcaagga taccgaacgc aacatgtttc ctcatattgc gttcttcctc aaaaacggtt
     5881 ttgactcctt ggacagcaaa ttccacggac atcaggaaat gtttgttttt ctctacgttt
     5941 ttatcttttg agtccatagg catccaagat ctctttctgt aaaccaaaca tttctttctc
     6001 atcttctggt gtcatatggt catacccgtt gatatgcaag aatccatgta ccgctaaaaa
     6061 gccaagttcc cgatcatatg aatggccgta agcttctgct tgttcagcag cacgttcaat
     6121 agagatcatg atgtctccta gtacacgagg caatggattc tctccatctt caaaaatcac
     6181 tgggatttcg tcttcgcctt cttcttccag agcaaaactg atgacgtctg tcggtgcatc
     6241 ttttccacgg taatcacgat tgattacttg gattgccgca ttgtccatga aagtaacaga
     6301 catttctgtt tcctctggca gctttaaata agatgctgca aattgcagca agtcatcgat
     6361 ttctttcatt ttctcttctg agacttggtt tgtttcatcc ataaaggtaa tatccattat
     6421 acatcgcttc tttctattct tcttgttctt cctttatctt ctcaacttct gttttcattt
     6481 taggatattt gatccgagaa tggaaggtgc tacttaaacc gctgatcaat gatttttcca
     6541 cttttcggat ttctttcaag gtcaatccac tatcgtctaa ttgaccatcg gaaatacgct
     6601 cttcgataag attatggaca aaactttcga ttttttcgct cgttggatga tccattgccc
     6661 gtactgcagc ctcacaactg tcagcaatat tgacgatccc tgcttcacga ctttgcggtt
     6721 ttggtccagg ataacggaat tgctcttctg ttacttccgg attgcgttct ttcgctttga
     6781 tgtagaaata acgcattagc gtggttccat gatgctgttt gcaaatatcg atcaccattt
     6841 gcggcatatt ataatcttcc aatattttgg ctccatctgt cacatgtcca aagataatat
     6901 gtttactgtc ttctggcaat aagaaattgt gcgggttttc cgctcctgaa ggcaagttct
     6961 caacgaaaaa gctagcatgt ttgatcttgc cgatatcatg ataatagcaa gctactcgag
     7021 ttagtaaaga acgtccgccg atttctgcta cagcgttagc acttagatta gctaccatca
     7081 tactatgatg atacgtacct ggcgcttctt ccagcaactg tttcaataaa ggatgatttg
     7141 gattgctgag ttcatttaat acaattacac tgtcatcatt gaccatcaat tcaatatatg
     7201 ggtgtagacc gatcgtcagc aagaatgaga agagtgcacc agtgaacccg cagacaagca
     7261 ttaaccaagt cgttgcatca ccaaagctca ttccttgata gacgatcaaa atgacatcca
     7321 tcatcacagg aaaaataatg acccacatgg cagcagataa tccttgttct gagatccgtt
     7381 tacgtctgac aatcgttgcc atgagcccag agaaaacata agacatcaag ataatcgtta
     7441 gaaagttcgt gccaatcgaa tcataaaaaa tgaaaagtgc ggatactgct tggaaaatac
     7501 cagccatgat ccctgctctt cgattcaaga aaaagcttaa aacaagtggt gcaaaagcag
     7561 cgggataaaa cagcgggata taagtagctt gttccgtttg gaataattgg aaaaatttca
     7621 tcagcactat gctgactgac atagctgtca catagaaaag aacgtatttt gttctttctc
     7681 ctgtattttg gaattgaagt gaattataaa tcagtacgcc gatttgaagc aaaacagcta
     7741 aaaccatggc aattagcgga aaaatcgaag ttgtttgatt agtcagtcct agtaattcca
     7801 attttttcat agctgaagca tcaatttgat taccttcacg aacaatgatt tctccttgga
     7861 agatcatcac tggttgtaca gcttctcgtg cggattgttt caattcttct gtctttttct
     7921 cattcaatac gtcattcact acgatacctt gatccactaa gtagcgaatc atttgttgtt
     7981 gtgctggtgt gacattcaaa tattggattt gctcttctgc ttcttgttta aaagcttcca
     8041 attcactttc acgaacttgt ttgctcatct gttcgtcaat gagcttcaga ctctcatccc
     8101 tcacagtatg aatctcagtt tcagtcattt caaatatcgt cgaataaaaa ttgttcggta
     8161 gtttttgata aaacacaaca ttttctgcat tcacattttc aaaatttttc ttcagcgcgg
     8221 cgatccgctc ttctgtagta ggctttggga tattttcatc ttcctttgcc ttatcaatct
     8281 tttcgtcata agatttgttg atggcatcat tcgtcttatc gatcaattca aatagttgct
     8341 tgatccgatt gttctggtca tctgcaagat ctttttggta agtgtattct ggagtgactg
     8401 cttctgctgc cagttttctt ttttgttcgg tttcttccgt gttctcgatc gttttgttcg
     8461 cacggatact ttcttctgct acttggcctt ctctgaaatc attggccttt tgtttgacac
     8521 tactaaatgt aacgccgcag ataatgataa aaaacaagaa cagcaggaaa ggcaatgctg
     8581 cctttccaag tttttcttgt agtttctgca gtgttttatt caacatgtgc ttatcctcct
     8641 aagcaaagct tattcttgat ggagatctgc cttttcataa gctttgatga tttcggcaac
     8701 tacagggtgc cgaacaacgt cacttgcttc aaaattaaca aaatcgattt tcttgatttg
     8761 ctttaatgtt cgttctgcat gaacaagacc acttgttgtc cctcgaggca gatcaatctg
     8821 actcgtatct ccattgacaa tcatttttga ttgataacca agacgtgtca ggaacatttt
     8881 catctgagca actgtcgtgt tctgtgcttc atccaaaata acgaatgcat catccaatgt
     8941 ccgcccccgc atgtaagcta aaggagcaat ttcgatcacg cctcgttcca tcaatcggtt
     9001 cgtatgatct aatccaaaaa tttggtataa agcatcataa acaggacgca gataaggatc
     9061 tactttttct tttagatccc cgggaagaaa gcctagattt tcccctgctt ccacagcagg
     9121 ccgcgtcaaa atgatttttt gcacttcacc ttttttcaag gcagcgattg ctaatactac
     9181 tgcaagaaaa gtttttcctg tcccggctgg tcctacgcca aatacgatat catgtttggc
     9241 taccgattcg acatatttct tttggccgct gttttttacc cgtataggtt ttccattacg
     9301 gtctttgacg atctcttcct catacatctc aacaaaataa tctaatgtgc ctttttgccc
     9361 cattttcagt gccgtcacga catctggtgt acttacatgg attcctcgtt tgatcaattc
     9421 ctgcaatgtc cgaatgactg aggcagccaa ggaaatctgg gattgttcgc caatgatctg
     9481 aatgatttct ccacgtgtat ggatggttgt ttctgttgtt tcttcaatca gttttatgtg
     9541 cttgtcgtgt gcacctaaaa gcatgctgac atcatcagca gccgtcaatc taatctctaa
     9601 agaactagac tcttccgtca aaaatagaca tccccttttt ttcgattcat tctttcctat
     9661 tttaccatac tcagaagaaa ctatatagca aataagaaaa ggttctaaaa gagttgctta
     9721 accataagta ccaagaaacg ttaaaaaata gctgcttcca ttctctaaag gtctcgtttg
     9781 aataaaaaaa gctgatcatg taagctatgc ataagataga ggacaagtat tccgtctaac
     9841 ttagcaagta ttctctgggt atttttcttg tttcaaaaaa agaaaacaaa atatttgaaa
     9901 tattcttgca tttcaaaaaa aacaggtgta ttataacgtc aacaaataaa tatacagcaa
     9961 agcgtcgagg aaaacagtag gctattcagt gatttattcc cagtgagtca tgtaagtgag
    10021 aaatgacaat aaatcgaata gacgaacatc atttccgagt caatgtcgaa aacgtagatc
    10081 attgtggctg cctccattat caggccagcg gataacttta tcgaaaagcg tccgtgaatg
    10141 aagaagcttt tttaagcgaa aaaaggtggt accgttctag aatctagagc ccttttccca
    10201 agtggaaaag ggcttttttt atattttaag gtggtggttt tcatggaatc tgatattagt
    10261 ggtatttcta gtttctgcaa cgtttatttt gttactcaaa atgataatta ttggaggaaa
    10321 aatttatgga agaaacaaaa acttattcat ggaagcaatt attgatggtc agttcactta
    10381 tcttcgggat gttcttcggg tcaggtaatc tgatctttcc tgtccactta ggtcaaatgg
    10441 ctggatcaaa ctggatcagc gctggtgtag gatttgccat ctcaggcgct cttttcccat
    10501 tattagctat cttagctgta gtagtgacaa aaagtgatgg tctgtatgac ttagctaaac
    10561 ctgtcggaaa atggtatgct gccttgttct tgatccttgt tcatttaacg atcggaccat
    10621 tctttggtac accgcggaca gcagcaactg cttttgaaat ggctgctaaa ccctttttgc
    10681 ctgaaaaata tgattcatta ggtatgtttt tattctctgc tcttttcttt ttacttgctt
    10741 atttccttac tgtacatcca acacgtttgg tcaaatatgt cggaaagtat ttaaactcct
    10801 tgtttcttgc attattagct atcatttttg tcgtttcttt attccaaccc atggggaatc
    10861 taaaccaatc tgctgcagat tcttatcaga cgaacgcttt gacaaatggc gttttagaag
    10921 gatacaacac ggttgatgca gtagctttac ttgctttaag tgtcactttt gtccatgcag
    10981 ttcgtgatct tggttttaaa gataaaaaag tcacagaatt aacagcaaaa gctggtagcc
    11041 tgagcgttgc gttagaagtc atgatttatt ttggtctggt ccttctcggt gcgatgagtt
    11101 tgaataagat gtctttatca gaaaatggcg gaactgcact ttctcagatc actaattttt
    11161 atttaggtaa cttcggtgct agcttcttag gggtaatggt cacattaggt gtcttcacta
    11221 ccgctatggg actcgttgtt tcttttgcac aagatttcca taaactgttc cctaaagtca
    11281 gttatatgac atggctgcgg ttaacgactt ttgtctcttt tgtcgttgcg aatgccggat
    11341 tggataatat catccaatgg tctttaccag tattgatgct tttgtatcca ttgtcacttg
    11401 cgttaatctt gctttcctta acagcaaaat tcttccaaaa gagtccattt gtctatcaag
    11461 taacgatgtt cttttctgcc gttccagccg tattggatat gttggcaaat tcgcctgcat
    11521 tagtgagtca gcaaactgtc gtagcaagct tactaggatt ttatcatcat tatgttcctt
    11581 ttgctgcatt aggacttggc tgggtcgtcc caacgttgct tggttacgct ggcagcttgc
    11641 tcttttatta tgtatatcgc gtatcaggat ataaacaaga agcaagtgag ttaccagaag
    11701 aataaccaaa tcaaacacaa tttaacataa gagatattaa acaggaaaaa
//
LOCUS       DAPBCF010000069        11441 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.071, whole genome shotgun sequence.
ACCESSION   DAPBCF010000069 DAPBCF010000000
VERSION     DAPBCF010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11441
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.071"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            127..1386
                     /gene="lysA"
                     /locus_tag="RD508_002445"
     CDS             127..1386
                     /gene="lysA"
                     /locus_tag="RD508_002445"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDT7736977.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKERSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1373..2173
                     /gene="dapF"
                     /locus_tag="RD508_002446"
     CDS             1373..2173
                     /gene="dapF"
                     /locus_tag="RD508_002446"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDT7736978.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDTDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2176..3057
                     /locus_tag="RD508_002447"
     CDS             2176..3057
                     /locus_tag="RD508_002447"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDT7736979.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGKEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3054..3770
                     /locus_tag="RD508_002448"
     CDS             3054..3770
                     /locus_tag="RD508_002448"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDT7736980.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3776..4471
                     /gene="dapD"
                     /locus_tag="RD508_002449"
     CDS             3776..4471
                     /gene="dapD"
                     /locus_tag="RD508_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HDT7736981.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAGTVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4487..5488
                     /locus_tag="RD508_002450"
     CDS             4487..5488
                     /locus_tag="RD508_002450"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDT7736982.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5485..6846
                     /locus_tag="RD508_002451"
     CDS             5485..6846
                     /locus_tag="RD508_002451"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDT7736983.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYSKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6806..7957
                     /locus_tag="RD508_002452"
     CDS             6806..7957
                     /locus_tag="RD508_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDT7736984.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSGAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFHYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSRSKEERVYNDEFIQSI"
     gene            7932..9101
                     /locus_tag="RD508_002453"
     CDS             7932..9101
                     /locus_tag="RD508_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7736985.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPKHVKQAGIAAIEEDFSHYTGMRGLEELREAACMFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9277..10656
                     /locus_tag="RD508_002454"
     CDS             9277..10656
                     /locus_tag="RD508_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7736986.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSVSDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            11060..11441
                     /locus_tag="RD508_002455"
                     /pseudo
     CDS             11060..11441
                     /locus_tag="RD508_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3823 a         2003 c         2541 g         3074 t
ORIGIN      
        1 aaaaatattt cgaaatatac tagacaattc agaaaatttt gtttaatatt attccaataa
       61 aattcaaatc tttatcaaat gaaattccaa taaaaacgga aaaaaagtga aaagaggaat
      121 gaaaaaatga cagaattgat aattggcgga gtcacagcaa gcacattggc agaaaagtat
      181 aagacacctc tgtatgtgta tgatgaagaa aagatgagac aaacgatgct gtcattcaag
      241 cgaggctttg tatcgaaacg ttttgataca aaagtacttt acgcctctaa agcattccaa
      301 acgattgaga tgctgcattt agttcgtgaa tatggattcg ggctagatgt tgtcagtggt
      361 ggggaaatct ataccgcttt gcaagctgat ttccctagag atactatcta cttccatggt
      421 aacaacaaga cgccagagga actgatctat gcacttgaaa atgatttgtt gcatattgtt
      481 gccgataatt tgatggaagt tgaattatta gcagaattaa gccaacgcta tttaaaaaaa
      541 atctgtatca tgcttcggtt gaatgtcgga gtagaagcac atactcatga atatatcgtc
      601 actgcgcata ttgattcaaa attcggcatg agctatgaaa gtaaagagtg ccaacaagcc
      661 cttcagttga taaaagaaag aagctatcta gagttagaag gatttcatgc tcatatcggg
      721 tcacaaattt ttgatgttac tgcttggtta gctgaaatcg acaaattgac gaattactta
      781 accgattttg accaacctct ttccttgaat cttggcggag ggtttgggat tcgttataca
      841 caaaatgatc agccaatccc agtcgaagag gcactaaaaa aactgattga atatacggaa
      901 gaagctttgg aaaaacgaaa actgaccatt cgtcaattac tgattgaacc gggtagaagt
      961 attgttggag aagctggtac aacactatac acgattggtt tcatcaaaaa gacaccacat
     1021 aaaaaatatt actttgtaga tggcgggatg acagataata tccgtccagc tctgtatcag
     1081 gcagaatacg attgtgattt agcagcaaaa ctgtcggaag aaaaaacaga gaaagtgacg
     1141 attgcaggaa aaatgtgtga atcaggcgat gtggtaatta aagaagctta tttgccgaaa
     1201 gcagaatcgg gtgatctttt agctgtttat tccacgggag cttatggata ctcgatgagc
     1261 agcaactaca atcgagcgac acgaccagca gttgtttttg tcaataatgg ccaatcaaga
     1321 ctgattgttc gcagacaagc attttctgat ctactaaggg gggaagtttc ctatgatcct
     1381 tcataaatat aatggctgcg gaaatgattt tatcttatta gattacgcag aagacacaga
     1441 ttatagtcaa ttagccgctt ctttatgcac aaaagaaaaa tatgatacag acggattgat
     1501 cgccgtaaaa atcgatccgt tggaaatgat ctattacaac aaagatggca gccgcgcgcc
     1561 gatgtgcgga aatggcattc gctgttttgc tcgatacgta aatgatcaga acatgatgaa
     1621 tgaacaggaa ttcaacgtag agacattagc aggcacaaga aaaattacgg tgttggatcc
     1681 ctcacctttt tattgcagcg tagatatggg agtgccagat gattctccgg aaaaaatcaa
     1741 agctaatcaa acttatccaa taaaaaacca ggaaatagag atcaatggtg aaaaagtaac
     1801 gatcactagt ttatttttag gaacgattca taccgttgtt tttgttgaaa atgcgcgtga
     1861 ggaagtctgg agaaaaagag gtgaactgat ctgtcatcat cctttgttca aagaaaaaac
     1921 caatgtcaac tttgtagaag tagtcaatga acaagaattg atcgtccgta cctatgaaag
     1981 aggagtaggt tggacacttg cttgcggtac aggttgctgt gcctcttatg tggttgctaa
     2041 ggaaactggg aaaatttcag cagatcaggt agttgttcac ttggaacaag gagacttgat
     2101 gatctctggt gaggatgcga tacaaatggc tggcccagca gttcatgaat ggacaagaat
     2161 attggaggaa tgaagatgat aaaaggttcg atcgtggcgc tgatcacgcc gatgaatgaa
     2221 gagggatcag tagattatgc tggtttggaa aaattgatcc aattccattt agatgaacaa
     2281 acagacggat tattagtttt aggtacaaca ggagaatctt ctacgctcac acaatctgag
     2341 gaggagcaga tccttcaact gacagtaaag aaagtggctg gccgtgtgcc ggtgattgca
     2401 ggagctggaa cgaataatac gaaagaaacg attgaaaaag cgaagcattt tgcttctttg
     2461 ggggcagacg cacttttggt catcacccct tactacaaca aaacaagtga tgcaggacta
     2521 gctgctcatt ttacagcaat tgcagaagcc tcaccgattc cgcttatttt gtataatgtt
     2581 ccttctagaa caggcatgtc gattccaatc catgtattag taaatttagc agaacatcct
     2641 aatatcattg gtttgaaaga agcctcagga gatatggctt atgtgatgga tgccgctcgg
     2701 ttgattggaa aagaattctt cctttacagt ggaaatgatg atttgatcct accagtaatg
     2761 agtgtaggag gaagcggtgt aataagtgta tgggcgaata tccaacctaa aatagtccat
     2821 gaattagtaa aagatacgca ggacggaaga tggcagcaag caaaagaaaa gcaattaaat
     2881 gcacttgaac tgatccatgc cttgttcagt gagaccaatc ctattcctgt caaagcagcc
     2941 atgtcattat tagacttacc ttccggacct ctacgcctgc ctttagtttc tctttcaaaa
     3001 gagaaaaaga aacaattagc tcagcttttg ttaaaagaaa ggacggttga aaaatgaaaa
     3061 tcggactgat tggcagtgga cagatgggaa atagagtcga agaagttgca caagaaagag
     3121 gagatacggt ccttctttta cggacggcac ctaaagaagc aactacgctt gcttttacgg
     3181 aactgccaga actgcttatt gatttttctc atccagataa tttagagaaa atcctttcgt
     3241 atagcttgtc ttatcaactt ccgttagtca ttggcacgac aggttataca caatcacagt
     3301 tccaagaaat aaaagaacat gccaaacatg tacctgtgat gtatagtgct aatttttcgt
     3361 tcggcatcat ggtgatgaat caactaatca agcaagcagc tgcaatgttg caaggctggc
     3421 agatcgaact gattgaaaaa catcatagtc gtaaaaaaga tgcaccatct ggtactgcaa
     3481 atatgctgct tcaaacaatc caagaagtgc aaaagctgca gcccgtatac aactggcaag
     3541 ggaaaaaaag agaagaaaac caaattggtg tacacagtat tcgtgcaggt tctttacctg
     3601 gtgaacatga tgtattgttt gctgctactg atgaaatatt tacgatcaaa catgaatctt
     3661 tttctaatcg aatctttgct gcaggcgcag tagaagcagc ggactggttg aaagatcagt
     3721 caccaggtta ttacaaatta gaagatttat taatggacaa aggggtgtaa aaaacgtgga
     3781 agctcaagaa atcatccgct acattcaaac ggcatctaaa aagacgcctg tgaaagtcta
     3841 tctgaatgta accgagccaa tcgaatttaa agaaagtaaa gtttttggtg aaggaagcag
     3901 cttcgttgtt tttggtgact atgagacgat tgctccggtt ttagaagctg aatcagaaaa
     3961 aatcattgaa atcgaaatcg aaactgctgc aagatacagc gcagttcctt tgctagatat
     4021 taaaaaaatt aatgctcgta tcgaaccagg tgctattatc agagatcaag tgtcaatcgg
     4081 caacaatgcc gtgatcatga tgggagcgat tatcaatatt ggtgcagtaa tcggtgaaaa
     4141 cacgatgatt gatatgggtg ctgtcttagg tggacgagcg acagtgggca aaaactgcca
     4201 tattggtgca ggagctgtct tagcaggtgt gatcgaacca gcatcggcca aaccggttat
     4261 cgtagaagac ggcgtactgg taggtgcgaa tgcagtgatt gttgaaggtg tccatattgg
     4321 aaaagatgca gtcgtggcag caggagcagt ggttttagaa gatgtggcag caggaactgt
     4381 tgtcggtgga atacctgcac gtgtattaaa aataagtgat gatcagacaa aagaaaatac
     4441 agcattgatt gctgcgttac gcgaattata gaggagatgg agaaaaatgc gcgaaataga
     4501 tacctgtatt gtgggggcaa ccggattagt cggccaaacg atgctcaaag tgttagaaga
     4561 atatgatttt ccagtaggac gattgaaatt attagcttca aaacgttcag ccggtaaagt
     4621 ttgtgtattc aagaaaaaga aacacactgt acaggaattg acagaaactt catttgaagg
     4681 atatgattta gcgctatttt ctgcaggtgc ttctgtatcc aaagagtttg cgccaatcgc
     4741 acgaagtcag ggactatttg tcatagataa ttcctcagca tggcgggaag attcggatat
     4801 tccattaatc gttccagagg tcaatctgga agactataca ttgaatcggc tgattgcaaa
     4861 tccaaattgt tcaaccattc aagcggtact tccgcttaaa gctttacaag aagcctttgg
     4921 tatccagcga gtcaattatt cgacctatca agcagtttct ggttccgggc aaaaaggcat
     4981 tgaagatctt catcgtacgc aaaatgacga ggaaccagtt ttgtatcctt ataatattag
     5041 ccaaacggtg attccggaaa tcgatcagcc tttggaaaat gggtatacaa aagaagaaca
     5101 gaaaatgata aatgagaccc gtaagattct gcatcagcct gctttgccag tatcagcaac
     5161 ctgcgtacgt gtgccaatcg aaaatggaca tggagtctct gtggcagttc aactgcaaaa
     5221 agagtttacg acggaagaaa ttagagagtg tctcagccag tttccaggga ttcaattaga
     5281 agatgatcta gcagcacata aatatccgac gagcattctt gctagaggaa cagatatggt
     5341 ttatgttggg aggatcagaa aagacacttc tttagagaac ggattgttgt tctatacgac
     5401 tgccgataac atacgcaaag gagccgctgc gaatgccgta cagattgctg cagctttaat
     5461 gcagaaaata gcggaggtgg caagatgagt aatacgctga aagtagcgaa attcggcgga
     5521 acatcgatgt ctcatgaaga gcaattcaaa aaagtccgta caattgttct ttcagatccc
     5581 aatcgccaag tgatcgttgt ttctgcttta ggcaaacgta cgtcagatga tgacaaagta
     5641 acagacttac tttatttgat ttatgcttac cttcagcatc atgttgattg gacacccctt
     5701 tggaaaagga tttgtgatcg tttcattcaa gtaagagatg ttcttgccct gcagttacct
     5761 attgaagatg aactagcacg catacagaaa caactggaag acgaaaagat aactgaagat
     5821 tatttagtaa gtagaggtga atatctgact gctcaactga tggctgagta tcttggttac
     5881 cagtttattg acgcaaaaga cctgattttc tttgactatg atgggaaaat cgatcaggaa
     5941 aaaacagcac aggaaatcac aaaagcattt aaaagatatt cgaaaatggt tgttccaggg
     6001 ttttacgggg cgaaccctgc aggaaaagaa aaattattgg gccgtggggg aagcgacatt
     6061 accggcgcga tactggcgaa gatgttgcaa gcggaaagtt atgagaattg gacggatgtt
     6121 tcaggaatca tgatggctga tccgcgaatc atcgatcatc ctaaaatcat cgaggaaatc
     6181 tcttttagag aactgagaga gatggcttat atgggggcta acgttcttca tgaagcagct
     6241 gttttcccag ttcaagaggc tgatatcccc atccaaataa aaaataccaa tgatcctttc
     6301 gctcaaggga caaaaatatc gaatcacgaa atagaaaagg aaaatggact gacaggaata
     6361 gctggacgca aggattttct ttccatcact ttatttaaac gacatatgtc cgatgaaatc
     6421 gggtttatct ggaaagcaat gagcattttt gctaaacatg agatatcaat cgaacatatt
     6481 ccttcaggga tcgacaatat cggagtgatc gtctcagcag aagcgattgc cgataaatta
     6541 tttctcatca cgaaagaatt aaaagaaaca cttggcgtgg aagaaatcgt cgtgattgaa
     6601 gacttagctt tgatctctgt cgttggcgga ccacataaag aattgatcgg tttatctgga
     6661 aaagtgttat cgatattgaa caaattagaa attcgcacat cgatcttatc acaaggagca
     6721 caggagttga atctgatcat cggtgtaccg aataaccaat atgaaacagt agtgaagggt
     6781 atctatgaag ggatggtgaa tacggatgct gaaagaatat cgaatggcac tccatcaaat
     6841 tcctgaaatc ggatttcatg aattcaagac aaaaaaatat ttatatgaac aagtaaaaaa
     6901 cagcggggcc gttatccatg aaatcggcga aacaggacta ctcctttatt ttgataatca
     6961 gcaagaagaa acgattgctt ttcgaacaga tatcgatgca ctgccagtca aagaagaaac
     7021 gaatctctct tttgcttcta agcatgaagg gtatatgcat gcatgtggtc atgacggaca
     7081 tatggcgatg cttttagggt tgactgactt tataactaaa cacattgagg atcttattta
     7141 taatgtagta ctgatctatc agccatcaga agaaatttcc ggtggcgcac aaagcgttat
     7201 tcagtcagga ttgttggata aatatgaagt acaagcaata tttggctttc atctatggcc
     7261 tggactagct aagggagaag ttttctctcg accaggacct ttgatggcac aaagcagtga
     7321 aacagacatt atcattaaag gccagtctgc acatattgct tctagtgaaa aaggaatcga
     7381 tagtctggag gcagctgtac gatttttgaa gaatgtttat gattttgacc ggcaattacc
     7441 ggcagagtgg aatcatctaa tgaaatttgg ccaaatccaa ggtggaacga tccgaaatgt
     7501 tttagctgga gaagttattg tatctggaag tatccgttct tacagttcag atatgcaaaa
     7561 ttatttgaag aggggattag accatttagc agaacagttt cactctacag ctactatttc
     7621 ttttcactat aatgacggct atccagctgt aatcaaccat agaggcttat atgcagcact
     7681 gttagattca aacaaactac atgaattaga tgctccagtt cttcaagccg aagattttgg
     7741 catatatacg caacaatatc catgtgtatt tttcttttta ggtgtcggtg atacccctgc
     7801 tttacatgat ccgacgttcg attttgatat ggatgtttta gaaaatggtg tagaatggta
     7861 caaaacgatt ctttttacag aaaatcttct tgtaaaaatc gatagcagat caaaagagga
     7921 gcgagtatat aatgatgaat ttatccaatc gatttagtcc caggctttct agaatagaag
     7981 tatcaaaaat acgacaattc gatcagcaaa tatcgtcgat accagatgtg atcaaactca
     8041 ccctgggaga accggatttt ccaactccta aacatgtcaa acaagccgga atagcagcga
     8101 ttgaagaaga cttttctcac tataccggaa tgagaggatt agaggaactg cgggaagcgg
     8161 cttgtatgtt tcagcaacag cgttatggat taacttatga tccgcaaacg gaagttttga
     8221 cgacagttgg tgcaacggaa gcgattgcct ctgcgttgtt atctgttttg gaagaaggag
     8281 acaaggttct tattccagcg cctgcttatt caggatatca gccattagtg gaactagctg
     8341 gtgctgaatt gatcccgata gatacttctg atacagggtt tgtctgtcag ccggaacaat
     8401 ttgaacgagc atttgaacaa tatggatcag ctgtcaaagc agtcatttta aactatccta
     8461 acaatcctac tgggacgaca ttgtctgcaa aacaattgaa agcaatcgct gaggttttaa
     8521 aaaaatatcc ggtatttgtt ataagtgatg aagtatatgc tgaattgact tatagtggaa
     8581 cgcatatgtc catagctact tatcttccag aacaaacaat cgtgataagc gggttatcca
     8641 agtcacatgc gatgactggt tggcgagtgg gctttatttt tgctcaaaaa gcccttattg
     8701 acgaactaat taaagtccat caatatctgg tgactgccgc tacaacgatg tcgcaaaaag
     8761 ctgcagctga agcgctaata aatggggtga aagatagcga gaatatgaaa gagcaatatc
     8821 aaacacgaag agactatctg gtccagcaat tggcgccttt aggatttgaa gtgacccagc
     8881 caaacggtgc attttacttg ttttgcaaac tcccagctgc cattcaaact gactcttggc
     8941 agttttgtgt agaattagcg gaacaggcaa aagttgcgtg tatcccagga attgcatttg
     9001 gcccagaagg agaaggttat atccggattt cttatgctag cagcatggaa aaattacatg
     9061 aggcctgcaa acgaatcaaa gactttttaa cagaacagtg attcatagat tttatcaaaa
     9121 aaacaatcgt taattttgcg gtatattctg caaaattaac gattgttttt taaatttagt
     9181 tcaaatgaac gcgtttcttt tgattcataa ctaatgtaat gttaagttta aattgtttag
     9241 aatgatttta aaagaatatt caaggaggtt tcatcaatgg aaaaaatcaa agttgtcatt
     9301 gtaggtgcat ctcatggagg gcatcaatca atcttggaac tattgacacg atacggtgaa
     9361 aatgtagata tcacgctatt tgaagcagga gactatattt ccttcatgtc atgtggtatg
     9421 gagctgtatt tagaagacaa ggtaacagat gtaaatgatg tacgtaattt cagaccagaa
     9481 aactttccgc aatccaatgt tcatatttta aataatcacg aagtaaaaac gatcgatgcc
     9541 gataaaaaaa cagtaacggt tactagcgta tcagataacg aaacaaaaga atatccttat
     9601 gacaaattga ttttgagttc tggtgtcaaa ccaaacaatc tgccagtacc aggagcagat
     9661 ctagaaaatg tctacttgat gcgtggatac aattgggcaa ccaaaatcaa agaaaaatta
     9721 aatgatccgg ctattaaaaa aatcgctgtc gtaggtgcgg gttacattgg gatcgaagca
     9781 gcagaagcaa gccgaaaagc tgggaaagaa gtcgtattgc ttgatgtgat cgatagacct
     9841 ttaggcactt atttagatgc tgagatgaca gatattttag aacaacacct aaatgaaaac
     9901 ggtattgaag ttttgacaaa tgcaaaaatc gaagctttta ctggtaacgg aaaagttgag
     9961 gcaatcaaaa caagtgaaaa agaaatccca gcagatctag tcattcaagc tgccggtgtg
    10021 aaggcaaata cagaatggtt aaaagggatc gtcgacttag atgaacgtgg ctggatccaa
    10081 acaaatgaat acttgcaaac gaatcttcca gatgtgtatg cagtaggaga tgctacactt
    10141 gcttattcta tcccagcacg caaaaaaatg ccgatcgctt tagcgactgt tgcacgtaga
    10201 gaagcacgtt atgtagtaaa acatcttttt gaagaagtac caaacaaacc gttcggcgga
    10261 gtcgtaggtt cctctgcatt aagtgtcttt gactatcatt ttgcagcaag cggattgaat
    10321 agctttacag cagcaaaagc aggagtagat gtacgagtgt cttattatga agatacgtta
    10381 cgaccaaaat atgtaccaga agaacaagga aatccaaaag tgtccatcca attattctcg
    10441 gatccaatga cccatcaatt gctaggagga gcagtattat ctacctatga tgttacaggt
    10501 caaggaaatg tattggcact agcgatccaa aacaaactga ctttagaaga actagcagaa
    10561 gctgacttct tcttccagcc aggctttgac cgacaatgga gcatgttgaa tctagccgct
    10621 caacaagcgt taggagaaga accatttgta gaataagaaa acgaaatatt tgaaaagagg
    10681 ttgtgacaga agtggtcagc ttcaagaaat aagaaggaat tcacgaaaat cgtttctcaa
    10741 atttttgtga aatttcggct tatttttcga agaagttact tctggaacac cgtgagtcag
    10801 aggttgtgaa aaagctgcct tgcatcaagt aataagaaca gccaagtaaa aacagcttct
    10861 tatgttttta acttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt
    10921 ttcaaaaaag ggactgtgac acgatttgtg tatcgacccc caaaagttag accaaaaaat
    10981 ctaacttttg gaggtcggta ttttttatgg ttaaatatac ttttgaactt aaattaaaga
    11041 tcgttcatga ttatttggat ggcaaaggcg attggaccgt aaaaatccag atcaagagat
    11101 tgaagcggaa atgcttaaaa ttcgggagaa gcacaaggat tatggctgtt tacggatgac
    11161 caatgaacta agaaaccgcg gtttctctat caacaaaaag aaagttcagc gcctgatcaa
    11221 gaagctagga ataaaagtaa cggcatacac acctaaatca cggcgctaca attcttatcg
    11281 aggacaagtc ggagcagtag cccaaaatcg gatccatcgt cgtttctaca ccagtatctg
    11341 ccatcagaaa atcacgacgg atacaactga atttaaatac catgaagtgg atgccaaagg
    11401 cattatccgt caaaagaaat tgtatctaga tccttttatg g
//
LOCUS       DAPBCF010000070        11361 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.072, whole genome shotgun sequence.
ACCESSION   DAPBCF010000070 DAPBCF010000000
VERSION     DAPBCF010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.072"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(57..284)
                     /locus_tag="RD508_002456"
     CDS             complement(57..284)
                     /locus_tag="RD508_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7736987.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(387..2975)
                     /locus_tag="RD508_002457"
     CDS             complement(387..2975)
                     /locus_tag="RD508_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HDT7736988.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(2995..3654)
                     /locus_tag="RD508_002458"
     CDS             complement(2995..3654)
                     /locus_tag="RD508_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7736989.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(3703..4206)
                     /gene="trmL"
                     /locus_tag="RD508_002459"
     CDS             complement(3703..4206)
                     /gene="trmL"
                     /locus_tag="RD508_002459"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDT7736990.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(4427..5293)
                     /locus_tag="RD508_002460"
     CDS             complement(4427..5293)
                     /locus_tag="RD508_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDT7736991.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            5402..6043
                     /locus_tag="RD508_002461"
     CDS             5402..6043
                     /locus_tag="RD508_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDT7736992.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(6105..7466)
                     /gene="mgtE"
                     /locus_tag="RD508_002462"
     CDS             complement(6105..7466)
                     /gene="mgtE"
                     /locus_tag="RD508_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HDT7736993.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(7484..8383)
                     /locus_tag="RD508_002463"
     CDS             complement(7484..8383)
                     /locus_tag="RD508_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDT7736994.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(8385..9182)
                     /locus_tag="RD508_002464"
     CDS             complement(8385..9182)
                     /locus_tag="RD508_002464"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HDT7736995.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(9160..9864)
                     /locus_tag="RD508_002465"
     CDS             complement(9160..9864)
                     /locus_tag="RD508_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDT7736996.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            9995..10570
                     /locus_tag="RD508_002466"
     CDS             9995..10570
                     /locus_tag="RD508_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HDT7736997.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            10688..>11361
                     /locus_tag="RD508_002467"
     CDS             10688..>11361
                     /locus_tag="RD508_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HDT7736998.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLS"
BASE COUNT         3230 a         2471 c         2040 g         3620 t
ORIGIN      
        1 tttttcacat cttctattca attgtcccgc aaaccatttc ctcacgattg aaagaatcaa
       61 ggattcgcag ggctgccagg attcgttgga ttgttcggcg tgttaggcgg aaaaataggc
      121 gccttgtcta acgttttttc tagttttgat tcttcacgat cgtctcgttc tacatcagga
      181 ctttcattca atttgaattc tttttccatc tcatctaact ttttaaagtc attgccagat
      241 tcttttgcta atttcgctaa tttatcttcg gtttctttag ccataaagta acgcccccct
      301 tttgatttca gcttagcata tcacactgaa aaaacaaaag aaaacgctaa ccaacgatca
      361 tttttagcta tttctcatct ttaaaatcaa gcattttttg ccggtataaa atcgtaggga
      421 gaactgtttt ccataccaat catcggatct actaactggt tatcgatcac ttctgctgta
      481 agaacgaaat ctttagaaac agcaggttct acctcttctt tcttttcttc tccaacaaat
      541 gaagaaaaca gatctggttc cactgtttcc attacttggt ttttcgtttc attcgtccca
      601 ctgtcatctt ctacaggtag cttttctttt acaacccgtg gctcttttgt atagttccca
      661 tcttcaaatg gatcatttcc gaccaaagaa tcttcataag ctgctagttt ggtccggaga
      721 gtgatattca ttttatcatt atccatgatc cttgatttca acgtagtcat ccggcttgct
      781 gattcattcg ctacacaagt gacataggct tgctcttccc ctaacaaaat caacagttcc
      841 ttactgcgag tcactgccgt gtagagcaaa ttacgctgaa gcatccgctg atattgatgg
      901 accatgggca aaataaccat cttgaattca ctgccttgtg atttatggat tgagcaacaa
      961 taagaaagag tgattttatt ccattcgttt cttttataag tgacctcatt tgcatcaaac
     1021 tggataacta attcatccac tttatcttca gaatcttttg ccaagatgat acccgtgatt
     1081 tctcccatat ctccattgaa tacattcaat tcgggagtat tgactaattg gaggactttg
     1141 tctcctatcc gataaacggt gtcgttccaa tgtacttcct tttttccagg tttccctgga
     1201 ttgaatatct cctgcatcat tttatttaac gcatcgatcc ctgcaggtcc ccgatacatt
     1261 ggtgctaata cttggatatc ttgtgcacgg aatcccttat ttttcgcttt ttccacaatt
     1321 ttagagatca agggttcaat ttgataagca tcacttcgga aataggaacg atctttttga
     1381 ttctttgtga aatcttttgg cagacgtcct tctttgatct catgggcaag aggaataata
     1441 ctagaaccat caccttgccg ataaatctga ttgagttcca ttttgggaat ttgttcgatt
     1501 tccaaaagat catggagtac ttgaccagga ccgacagagg gaagctgatc tttgtctcct
     1561 actaagataa cttgcatatt cgtcggaatc gctttgaata atgtgttagc cagccatgta
     1621 tcgaccatag acatctcatc aacaatcaaa agtccgcctt ctaattcttt cgtactgact
     1681 gaaggtgttt tttcccgtcc attcagcccc agaagacgat ggatcgtact ggcaggcaga
     1741 cctgtcgttt cgttcattcg tttagctgct cggccagttg gtgctgcaag tagaatagga
     1801 aaaatttctt gggtatattt tgaaggatcc aattccagtc cgttcaactc tgcaaaaaga
     1861 ttgacgattc cgttgatcac agtagttttc cccgtacctg gtcctcctgt taaaataaat
     1921 agaggggaac ggattgcttc agcgatagct tgttcttgcg aaggtccata ctgtatgccg
     1981 aatatttttt cgatacgccg aatattcttc tgcacttctt tttcaggata atggatttct
     2041 tttttacgac tgagaaggcg ctggatcgaa ttaccgatcc cccattcaga aaagtacaaa
     2101 ctgttttcgt aaagattagt ctcttcttgt tgtatctttc cttcttcaac aagttggata
     2161 attacagtag caacctgatc aggctggatt tcaattgggc gacttgtttc taaaatacgg
     2221 atcgtttgct gaagcaatgt ctccgccggt acgtatgtat ctcctgtttg aactgcatgc
     2281 tgaaaaatct gatgcaagat agctgctcga attcttctcg gtgaatctgc tgcaataccg
     2341 atttgttcgg ctagattatc tgcacgtttg aacccgattc cttctatgtc ttcgactagc
     2401 tggtacggat tttcttcgat gatatccaaa gactcgttct tataggcctg gtagatactg
     2461 aaagctaact gactaccgaa cccgtaacga ttcagtccca tgatcacttg atccatcccg
     2521 tggtttagcc gaatcgtctc agcaagcatt tctctttttg gcttcgtcaa accggagatt
     2581 tgttttaata ccgaaggatc agcaatgatt ttttcgatag catcttctcc cagcaattct
     2641 acaatttttt ctgctgtttt cttcccgatt cctgggaatt tttcgctgga aagatacgct
     2701 acgatcccat ttgcagttgt tggcttttct tgctcatatc tttcgagttt aagctgcctt
     2761 ccgtatttag gatgatccac taattctcca taaaaacgat aagtctcatt ttcttgaata
     2821 tcgccgaaac ttccggtgac tacaatctct ttttcacggt aatcagctgt ggtttcactg
     2881 atgtgtacca aaagcacttt gtaaaaatta ctaggatttt gaaaaaaaat cgcggcaact
     2941 gtaccaacga aataaggcat ttcttctggc tgcatcggaa gccgcctcct tcttctatag
     3001 taaaggttct ggtgctgttt cagttcctaa aaaatctgtt tggttccata ctttcagttc
     3061 atatggcaat aatctgcaag gctcttcagt ctctaaaatc gtcaaactac tattgaacaa
     3121 tccacccatt tcacgcaact cacttagctc ttttcctgtc atccattgaa tggctgcagt
     3181 taaagaagct ccatgtccta cgaataaaag tgggccatct ttatgtcggg caaccgcatc
     3241 tgctacaaca gtttcgatac gtgtgattgc cgattcaatc gtttctccgt gaaaaggaga
     3301 aggatcatac agatctaaat gattacgcaa attcggcaga ttatccggat atttctggta
     3361 catttcatcg atcgactgac cttctaaagt acccagccct agttctctta gcttatctgt
     3421 ataaaaaatc tctaccggac gagcaagctc tttgttgata ccttctgctg tatcacgtgc
     3481 tcgctttgct gtactggaat aaattgcttt aaaaggaaca tattttacct ttttcccaaa
     3541 tgctttgatt tcttcgtaac tttgtggcaa aagcggagaa tcgccattgc tcccttgaaa
     3601 acgtctttcc tgattccatt gtgtcttccc atgtcgggta aaatatagtt ccatacgcag
     3661 caaactcctg tctttctttt attttactct ataataaact gtctaatcca gcttgtcatt
     3721 ttcatagtga tgcgtcaatt ctaaattagg gaatccttgc tggcgaagtg cttcatacac
     3781 tatcattgca gctgtattcg ataaattcaa tgagcggaca tgctcatcat tcatagggat
     3841 gcgtaaacac ttttcttcgt tttcacgcat aaatgtttct ggcaaaccgg ttgtttcttt
     3901 tccaaataaa aagaagtgct cttctccatc agcaaaattt tcgtcactat atactttatg
     3961 ggcaaatttt gagatcaaat gtagtttacg attacctaaa aatgttaaaa aagcttctaa
     4021 attactgtgg taagtaatat ttacatcatt ccaataatcc aaccctgccc gttttagatg
     4081 tttgtcatca gttgaaaaac ctagtggctc gattaaatga agcggagtat tcgtggctgc
     4141 acacgtacgg gcaatatttc cagtgtttgc agggattaat ggttcaaata aaacgatatg
     4201 attcatcagg atcattcctc tcatatttat gttcgtttct attttctgac aatttgattt
     4261 ttgcataaaa aaaaacgtat caactcggtg tcagtcactg cgagtcgtta cgttagtgaa
     4321 gctcttctca ctaactttta tcagaacagg aacctgataa aaaccaatga aaaaacaact
     4381 tgttgctaat ataacaccct caactttttt ttgcaacctc tactcattaa aaactgctag
     4441 aaaaacgttt tctcttagtt ccttttaata attctatgtc aattgtaatc ttcttcaaag
     4501 gattcttata taagtctgct ttgattcgct cttctacctg ccattctaaa ggtgacatgg
     4561 ccaaaagatc tttttgattt tcctctggta tctcaaattc ataggttaca cgctgacgtt
     4621 cagttaattt cattgcttca gcaaacttgg ctactacacg ttcattggaa taactctgtt
     4681 tttcaggttg attcggataa aaagcctgac gtagttcctt taaataattt tcttgtggca
     4741 ccaccttcaa cacttctcca tcttctgaga gtacacgttg gaattcttgg taatgagaag
     4801 gcgaaaagat atttaaaacc gcgttgaatg tttgatcagc aaacggcaaa ttggtcaaat
     4861 cagctacaca ccaaaatgct tcggcagatt gttctgtagc tgcgtagact ccttcttttg
     4921 aaatatcaaa tccaacagca ttttgaatct ttttcaattt tgaaagttca ttcaagaagc
     4981 taccttctcc gcagccaaca tctaatagcg agacttcttc aggtaaatgc tgcgcaatag
     5041 tctcaataac gggctgatac atgccagatt ggatcattct acgccttgga acgaacattc
     5101 cttgatcgta ttctgtttta accgcatggg ataaaaaata aagtgttcct tttttggaaa
     5161 ggtcaaaacg gtgattattt ttgcatatca agccattatc agactttttt acttcttctt
     5221 ggcaaaccgg acagcggaac agctgatgat tttctgccaa aaactggcgt cctcggtcaa
     5281 ttttttttaa catagttccc cctcatttct gttttatctt accgttagat gctcactttg
     5341 gcaactgcta aaaatatgat acaatgccta gaagaaagtg aaagataaag gagaagatta
     5401 gatgatcaaa gaattttgcg ctgaaaacta cacatctatt cctctagcaa ttgctagagg
     5461 agccgatcgg atcgaattgt gtgacaactt agcggtcggt ggcacaaccc cgagtactgg
     5521 tgtgatcgaa gaaacgttaa gttatgctgg ggaaaaagat atccccgtaa tgacgattat
     5581 tcgtcctaga gggggcgact tcgtctataa cgatatcgaa ttgaaaatca tgcatactga
     5641 tttgattgaa gcaaagaaat tagggacgga tggcgtagta tttggttgtc ttactccttc
     5701 aggctggcta gacgaagagg ccttagaact attgatcgaa acagcagaag ggttgcagat
     5761 caccttccat atggcttttg acagtattcc tgaagatcgg caattcgaag caatcgattg
     5821 gctggtagaa catggtgttg accgtatctt gactcatggc ggtcctgctg acaaaactat
     5881 tgtagaaaat ttcccacggc ttaaagaatt gattgcctat acagatggcc gcttaatcat
     5941 tttgcctggt ggtggtgtca ctgcagagaa tgcagcacat gtagctaaag aattgaacgt
     6001 aagcgaagta cacggaacca aaatcgtgga tcttcagtta taatcttata aacaaaaaaa
     6061 catttgcaac aggcataatg cttattgcaa atgtttttgt ttttttacat aaaatagccc
     6121 ataaataaag aagcaatatt gaaataaatc agtacactcg tcaaatcgct caaagtcgtg
     6181 ataaagggac cgcttgctac tgctggatca aatcctagac gatccattag catcgggatt
     6241 aaactacctg caagattcgc cactgtgatt gcaaatagca tagccatccc tatgacaaac
     6301 cccaagataa aattatgttt ccaaaaacct acgattagaa aaatcgtgat ccccgtaaca
     6361 gctcctgtga caacgccggt caagacttca gccaaaacaa gtcgaacaaa tccatgatct
     6421 ttctcatcag aaatcgcaag tcgacgaaca gccacagcta gcgactgggt tccagcatta
     6481 ccggcagttc ctgtaatcag cgaaatgaag actgctaaaa tactcgcttc acttaccaag
     6541 tcttcatagt gactgattaa agaagcggtc gacataccta aaaacaacag agtgatcagc
     6601 caaggcaaac gtcgagacgc tgcctttact ggattttcat taatttcttc cacattgacc
     6661 ccggcaagtc ctgaataatc gctagcagct tcatcatcaa taacgtcgat gatatcatcg
     6721 actgtgacga ttcctaacaa atgatcatca taatcggtaa caggaagagc taagaagtca
     6781 taatctctaa atgtttgtgc cacatcttct tggtcgtcgc ctacatgaac tgaaagcact
     6841 cgttcgctca tcagatcaga aatcattgcg tcgtcatcat tcacgattag gtcgcgcaga
     6901 gaaataaccc ctactagctg accttcttga ttaacgacat agatgtaata gattgtttca
     6961 gctacatctg cttcgttctt cagcacgtac atcgcagagc gaacagtttg attggctacg
     7021 atcgaaacaa attcagttgt catgatcgcg ccagccgttt catcctcgta atggagaagt
     7081 tccttgattt cactggcatc gtctgccgac atcaaactta aatatttagc aatttgcttt
     7141 ttatccagcg tattaagcaa gtcaacagca ttatctgtat acatctcaga aagcatatca
     7201 gctgcatagc taggacgcat ttcatctagg tattctttca tatgttcgtt gtcttcttca
     7261 atcacatcga acatatccgc taattcttta ggcgacagat aggaatagat cagctgcctg
     7321 ttctcttctg taagagattg gtagaattgc ccctgctcat agatatgcat ctctaaaaaa
     7381 ctgtttctga atgcctgaat attattttcc cttaaatctt gagtcaactg ggcaaatctt
     7441 tcctctaatt cttgattttc atccaaacca atctcacctc gccttattct tcaaaccgtc
     7501 tcacaactgc ctccatgtct gcggctaaag gctgcttgaa ctccagcaac tcttctgtaa
     7561 atggatggta aaaacgcaga tcataacaat gaagggcttg tctttttatt cccagatcca
     7621 ttcgcccgcc atacatatca tcaccgagca gggcacagcc aattgcggaa aaatgaactc
     7681 ttatttgatg tgtccttcct gtatgcagct ggatatcaac taacgcgatt tctgttagtc
     7741 gcttctctat ccagtactca gtctgtgccg aacgtccttc atcagagacc attcgcttca
     7801 atagcgaaga ataatctcgg gcgatcggca aatcgatatg tccatgtgcc gataaatctg
     7861 aaagccttcc actgactaag gcctgatatt ttttcacaaa cttcttttca cgaagttgca
     7921 tatctaattt tgcgtgcgca aatccatgct ttgcaaaaag catcaagcca gatgtatccc
     7981 gatctagtcg cgtcaccaca tggattactt ggttttcgta accttgtttt ttataataag
     8041 cctttacacg attagccatt gtcccatttg gatggtattg ggcaggaata gacgaaacgc
     8101 ctgctggttt atttactacc agaacgtgtt catcttcata cacgatatcg atcggtgttt
     8161 catccaaaag tacggtttca tgttctcctt cagcaggaat cacaatggtt accttatcat
     8221 ccttagctag agaaaacaag acattttcta cttgatcatt aactttgatt tgaccgcctt
     8281 gaaattttat tttcgctaac agaccctttg agatcccttt ttcttttaaa aaatatttta
     8341 cttgctgaga atgatctttc tcataatccc atgtaaactg catatcaatc ctcactaata
     8401 aaggcatctt tcacacgatg ccaaaaatgc atatgtcgat aagaagcaaa atggatccgt
     8461 tcttctgcta ttcgataata aattgagcgg atatttgctt ttgcgacatt caattgatca
     8521 accgttacaa gataatcttc tgtattttcc aattttattt ctagccattc atcatgggca
     8581 atcacgatcg gagaacccaa agtacgaaac actcgattat tcagtgaagc aatctctgcc
     8641 aactgaaagg cattgatact aggatggatc acagcaccgc cgacactttt attatatgct
     8701 gtcgaaccag taggcgtaga aatcgtcaat ccatctcctc taaaactttc aaacagctcg
     8761 tttttgatgt atacatcggc taccatcgta cgattggccc gtttaatcgt tgattcattc
     8821 agtgctaaaa aatgctggtc cggtgtttca tccaaataac tgatccgaac atccagcaag
     8881 ggataactaa cactttgttc ccggttcgtt cgtaagctgt ctactagttc ttccagctcg
     8941 taatcccgcc aatccgtgta aaaccctaaa tgacctgtat gcacgcccaa gaaacgcaca
     9001 tcattcagac aatgactgta gtgatggaac gccgacaata atgtgccgtc tccgccgact
     9061 gagatgacca attctggctc atgatcatct cgttgaatcc ctgcttgttc taaaagtgcg
     9121 ttcaaacgtt ctgtcacttc tatagtcttt gcttctttat tatgaacgat cgctactttc
     9181 atcccctgcc tcctctcttt cgctttcttt cttcaaaagc gttcgatagt agacatcatc
     9241 tgattttcct cttccatggg agaataaccg ctgtgcttct tggatttctt cacggatact
     9301 ggacatctct tcatccaact gataggcagc ttctgccgca cgctgaagtc gttcactcat
     9361 ttcttctgga aaaacgcctt gatatttata attcagcgaa tgctcaatcg ttgcccagaa
     9421 attcatcgca agagtccgaa tctggatttc cgccaaaatt ttcttctcac cgctgatcag
     9481 ctgtacagga tactcgatca ccagatgata agaacggtag ccacttgctt ttttatttgt
     9541 gatgtaatct cgttcttgga gaactttcat gtcttttctt ttacggatga tctcaacaac
     9601 ttgatggata tcttctacaa actgacacat gatccttaac ccggcaatat cagacatttc
     9661 ttcttctaaa cgtcccattg gaatatgccg taattgtgat tttgttacaa tactatcgac
     9721 tggcttgact ctcccagtga caaattcaat cgggacatgt cgattttgtt cacggaactg
     9781 tttgcggatc ccccgcagtt tcactttcaa ttctgataca gtttgttcat atggtgctaa
     9841 aaatgcttcc caatctcgtt ccatagctga tacctctact tcattaacat tcattgttta
     9901 ttctaccata tatgcaaagt tttttcgtac tcttgattta tgcattgacc aaaaaaagaa
     9961 aattaggcaa aatagacaaa aaggagtcga tcaaatgaca caaatgcttg aaatcgaata
    10021 taaatctatg ctgacaaagc aagagtacga gatattcatc gctcactatc aattaacaga
    10081 taaagatttc cgtgtacaga ctaatattta tttcgatacc gttgatgaac agctgaagaa
    10141 acaaaattgt ggcctacgga tccgtttcgt tggtcatcaa gctgaatata cattaaaaac
    10201 acctgctgaa aaagggcgtc tcgaaacaac ggataccttt ataacagaag aagcagaagc
    10261 atttatcttc gaaaaacgtc tgcctcgttc aggcgcagtt tttcaaaaac tttctgattt
    10321 gaatatcgat cctgcttcat taatccaaac cggaaagctt acaacaaaac gagctgaatt
    10381 ccctattgaa gaaggacttt tagctattga tgaaagctgg ggagacaatc tacacgattt
    10441 tgaactggaa ctagaggtag gggatgcatc tgtgggaaaa attgctttta taaatttttt
    10501 aaaacgtttt tctttacctt atcgtcctgc taagaacaag atccaacgta tgcttgaagc
    10561 taaaaattag aaacctttca ttttcacaag gcacttgagt tcattttttt acttttttct
    10621 gttaagttat aggatgtgaa agaatctagt cactagttgt atagaatcta ttttggggga
    10681 gattcatatg atcgaaatct atttatttgt taatccttta ggggaatact gtttcgaaat
    10741 ggaacaacag ttattacaat ttatcgaaga agagtacggg acaccatcaa aagaaaagat
    10801 gcaatttcgc tttcttcctt tggtcaattt gcagacaatt ggggatgtca tgcaacaaaa
    10861 aggaatttct cagaacaatc ttgaggaacg taatcactta ttctcaatga cttattctgc
    10921 agcattggac tgcaaagcgg cgcagtttca aggaaagaaa aaaggccgcc gttttttgat
    10981 caaattgcaa gaagcagtcg gctgtaatga cataccatat tctcaagaac ttgctgaatc
    11041 catatttgaa gaaatcggcg gcgatttgaa tatgtttaaa gaagatcgtc agtctgactt
    11101 cgttaaagaa gtattctttt ctgatcaaaa aattgctcgg gaaatgggca tcacaaaaca
    11161 cccttctgca gtcgtttaca attatgcctg cgaccgtgat tttggtgttt tagtagaagt
    11221 aaaaggtaca agtagccttt ggagaatcac agagctgtgt aaaacaacag ataactcata
    11281 tcaagttttt aatggtgaac atttacatac aaatgattct cagttccatt caagaactag
    11341 ccatttacac ttgctttcta a
//
LOCUS       DAPBCF010000071        11253 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.073, whole genome shotgun sequence.
ACCESSION   DAPBCF010000071 DAPBCF010000000
VERSION     DAPBCF010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.073"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="RD508_002468"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="RD508_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDT7736999.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="RD508_002469"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="RD508_002469"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDT7737000.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="RD508_002470"
     CDS             complement(2169..2906)
                     /locus_tag="RD508_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDT7737001.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="RD508_002471"
     CDS             complement(2997..3524)
                     /locus_tag="RD508_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737002.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="RD508_002472"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="RD508_002472"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDT7737003.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="RD508_002473"
     CDS             complement(4401..4886)
                     /locus_tag="RD508_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDT7737004.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="RD508_002474"
     CDS             complement(5039..5236)
                     /locus_tag="RD508_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737005.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="RD508_002475"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="RD508_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HDT7737006.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="RD508_002476"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="RD508_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HDT7737007.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="RD508_002477"
     CDS             9211..9423
                     /locus_tag="RD508_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HDT7737008.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="RD508_002478"
     CDS             9425..11104
                     /locus_tag="RD508_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDT7737009.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3265 a         2429 c         1971 g         3588 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaa
//
LOCUS       DAPBCF010000072        11150 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.074, whole genome shotgun sequence.
ACCESSION   DAPBCF010000072 DAPBCF010000000
VERSION     DAPBCF010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11150
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.074"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            6..305
                     /locus_tag="RD508_002479"
     CDS             6..305
                     /locus_tag="RD508_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7737010.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="RD508_002480"
     CDS             378..1739
                     /locus_tag="RD508_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDT7737011.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFLSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLLFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGILTMPIYLYGATYLAPILSDSAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="RD508_002481"
     CDS             1761..2021
                     /locus_tag="RD508_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737012.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="RD508_002482"
     CDS             2035..2787
                     /locus_tag="RD508_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDT7737013.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="RD508_002483"
     CDS             complement(2881..3486)
                     /locus_tag="RD508_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7737014.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIEQAREWTDHLLTK"
     gene            complement(3542..4516)
                     /locus_tag="RD508_002484"
     CDS             complement(3542..4516)
                     /locus_tag="RD508_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HDT7737015.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DCPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4894..5613)
                     /locus_tag="RD508_002485"
     CDS             complement(4894..5613)
                     /locus_tag="RD508_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7737016.1"
                     /translation="MPKYEEIANILRERIRSKEYPPDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5740..7011)
                     /gene="celB"
                     /locus_tag="RD508_002486"
     CDS             complement(5740..7011)
                     /gene="celB"
                     /locus_tag="RD508_002486"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDT7737017.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7164..8561
                     /locus_tag="RD508_002487"
     CDS             7164..8561
                     /locus_tag="RD508_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7737018.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWNHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSRLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKAIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGTIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8642..9082
                     /locus_tag="RD508_002488"
     CDS             8642..9082
                     /locus_tag="RD508_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7737019.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9229..9555
                     /locus_tag="RD508_002489"
     CDS             9229..9555
                     /locus_tag="RD508_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7737020.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9556..10305
                     /locus_tag="RD508_002490"
     CDS             9556..10305
                     /locus_tag="RD508_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737021.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10331..10741)
                     /locus_tag="RD508_002491"
     CDS             complement(10331..10741)
                     /locus_tag="RD508_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HDT7737022.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNK"
BASE COUNT         3538 a         1948 c         2291 g         3373 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttcgaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcctgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtctta ttgctgcttt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattacca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcctc acgatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgattcagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaaggaccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcaaaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgggagat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc tcgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccaatc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa aaatgaagta gcatgaagag
     3541 attattcacg ttttttattt gcatcacttg tatcgaaagg acggacatag gcttcaatgg
     3601 cttcacgacg ttcttctaag aatggaggaa gagatagttt ttctcctgct gattctgctg
     3661 gttcatcttc aaggaatcca ggacaatcag ttgctaattc aaacagtacg tgatgagcgg
     3721 ctaggaagta ctcagattgg aaatagaaac gatcgacgaa accagaattt ggcaattcaa
     3781 tcttattgat tacttgaatc cagtattcca atgcttcttt gtctgctaca cgcaatgcta
     3841 agtgatggat atttccaaat ccttcgattg cttttggcaa gtctgtccga tgttcaataa
     3901 tgatgcttgc accatttccg ccttcaccga tttcaaataa gtagaaatct cctgaatggt
     3961 ctgtttcttt gaatcctaag attttttcaa gaatcaagcg gatatgctct aattgactga
     4021 cacggacaaa gacaggtcca agtcctgtga tcgcaaactc tgtcggtaca ttgctgtttt
     4081 tccaaggaat gccagctgct acaccttgat tgttttcgtc agagatcaat tgataatact
     4141 gattatcgaa atcttcaaat tcgatatatt ttttgccgaa acgttcattg attgctgaat
     4201 gagtaacgtc atatttttca aaacgttcca accaaaagtc taatgctgcg tcacttggca
     4261 cacggaaaga agcacgagag atcgtatctg ttcctttttt tccttttggc tgatttggaa
     4321 aatcaaagaa agtcatatct gttcctggcg caccagtatc gtctgtaaag taaagatggt
     4381 aagtttcgat gtcatcttgg ttaactgttt ttttgattaa gcgcattcct aaaatatctg
     4441 taaaaaagcg gtagattttt gtagcgctag atgtcattgc tgtgacgtgg tgaattcctc
     4501 tgatttgtgt atccatgata aatttcctcc tgtcaactta caaaaagtaa gtagttgatt
     4561 tagacatagt atagagggtg catctctatt ttgcaattaa tttgtcttct aaagtatcag
     4621 gaaggaatca agaatggaaa agaggaggga cggatcaata aaataaaaag acttacgact
     4681 agctgtatcg atttcaaaaa aactagcttt aaaaagctaa ctttagaatc attacgggtg
     4741 gtcataagtc tttttatgct gagttatttt ttcatttttg agctaatgct taggatagga
     4801 tagaatgttg atttcacgat ctcttcttgt tacttgaaac tgcttactac tgtcacgatc
     4861 tcttggtaaa cggctttttc acaacctctt catttaagtt gaacgcacat ccagcacaga
     4921 atagttccga acatcaaatc ggtttcggct ggaagaatat tcaatcggct gtccatcttt
     4981 gagatagacg acttgctgaa cttccagtac aggatcgttt tctgcacagt tcaaatattg
     5041 ctgatcatat tcatcacttt tatctgcaga aatagcacga taagcccctg caaaatggac
     5101 attcaattct tgatgaagat gatcatagat agaggctaac aaatgttctt tttttaaacc
     5161 cggcacaaga tggactggca taaaagtatg ctctaaaaca tatggctcgc catctaagat
     5221 ccttaaccgg tgaatattgt agacaggttg ctcggcatcg atcatcaatc gttcttggat
     5281 atattgatta gggaattcaa catcaaaatg aatgatttga ctcttcaaag aacgatgtct
     5341 gcgtttcatt tggagactca aaccttcata ctcgttagcg ggcgatgtgt ctttttgcat
     5401 aaatggatga ttcaagattt tcgttcctga tcctcgctgc gaatagacaa gtccttccat
     5461 tgctaagata ttgatggctt ttttgattgt catccggctc gcaccaaatt ctttgaccaa
     5521 gtccacttga ttaggcaaaa aactatcggg aggatactct tttgaacgga tacgttctct
     5581 taaaatattt gcgatttctt cgtattttgg cacgttattc acctcttcta gagtataacg
     5641 aaagattatg cttccgacaa ctcgaagtag catctggaac attgtttatt cgaaaaaaga
     5701 ggtcgtgaca agtttttgtc acaacccctt aatgatctat taagcaatat ctaaatctgg
     5761 ttgtttatct agtactttca ggaatgggta ccagataaag gcaacgatga caaagtcgat
     5821 gacttgcagc ataccaccaa gccatgaatt tgttgctaag acaccgcttg caatgattgg
     5881 cacagtccat ggaacagaga cgccagttgg tgcagggaca agtccagcag ccattaccaa
     5941 ataattgaac gtcgttacga ttagaggtgc cacaacccaa ggaataagga ttgttgcatt
     6001 caatacgatc ggtagaccga agatcgctgg ttcatttaca ttgaaaatac caggtgctaa
     6061 agctaatcgt ccaacatcac gatactgttt ctttttaaga acaaaggcca tcaataaaac
     6121 gacagctaaa gtcattccag agccaccaat accaacagtg aaggtttcca tgaatggttt
     6181 tgtgatgatg tgtggtaatt cttttccatg ttgataagct tctaagttat caagcatcag
     6241 tgtattccaa atcgggtcca ttacagagtt gacgatgatt tgtccgtgaa gtccgaagaa
     6301 ccataagaat tggacaaaga acaaagcaat caatgttgca ggtaaactac ttcccaaacc
     6361 agttaatggt ttttggatca cttcataaac gacgtcatgt aagttagcat tgaaaatacc
     6421 agtcatcaca gcattgatta ctaagaaaat agttagtgtc actacagcag ggatcaaagc
     6481 ggcaaatgat tttgttactg caggcggaac tccatcaggc attttgatct gccagccgcg
     6541 tttcgtgatt ctgcagtaga tttctccagc caagaaagca gcgatcattc caatgaacat
     6601 tccttttgcg ccaagacgat caagtgaaag cacaccagtc acatcttcac cgccagcggt
     6661 tttcattgca aaaggcgtaa gaatcaagaa gctggcaaaa gacacggcac caccgaaaat
     6721 accttcaacg tcataagatt ttgataaata atagccgata ccaaaagtaa caaaaaccga
     6781 catgatgctc attgttgcat tttgcccatt accgaataag ttcgataaag ttccctttgt
     6841 tgcgtcactg aaaaaaggca agttattgat aacgacaacg atcgaaccga acatcgttaa
     6901 agggaaggaa agcatgaaag catcccgcag cactgtaagg taacgatttt gccctaataa
     6961 attagctaag ggcatgattt tctcagaaag cttgtccata aaaccgttca tttttattca
     7021 cctcaaattt atttgcaatc gattacatac aaagtataac gccaaaaatt ttaaatgtct
     7081 agtcattttc ataaaaagta ttgatttatt ttttagggtt cgttatgatt acgatatcaa
     7141 gaaaaaagag aggaagtaaa aaaatgaaaa cctacacatt cccagaaaat ttttggtggg
     7201 gttctgctgc tagcggaccg caaacagaag gaagagtaag tgatgatggt aaaggagaaa
     7261 atatttggaa tcattggtat gaattagagc ctgaaaaatt cttcgatcaa gtaggacctg
     7321 aaaaaacttc gcaagtttac acaaaataca aagaagatgt tcagttaatg aaagaaactg
     7381 gccataacac atttcgtaca tctatccaat ggagtcgttt gattccagaa gggacaggtg
     7441 aaatcaatca aaaagctgtt tctttttatc gagattattt tactgaattg ctggataatg
     7501 gtatcgaacc ttttgtgaac ctttaccatt tcgatatgcc actaccactg caagaaaaag
     7561 gcgggtggtt atcaagagaa acggtcgacg cttatgtttc ttatgcagca gcgtgctttg
     7621 aactgtttgg agatctggtc aaaaaatggt ttactcataa tgaaccaatc gtacctgtag
     7681 aaggaggcta cttgtatcaa ttccactatc caaatcatat caatatgaaa gaagcggtcc
     7741 aagtaggcta tcatgagaat ctagcaagcg caaaggcaat caaagcctac catgaaggcg
     7801 gacatgatgg tgagatcgga atcatcttga atctgacacc aagctatccg agagatgaaa
     7861 cgaacccaga agatgtaaaa gcggcgaaga tcgctgacgc attcttcaac cgatcattcc
     7921 ttgaccctgc agtgaaagga gagtttccac aagagttgat cgaaattgtc aaagaattgg
     7981 ctataatgcc agagatccat gaaggagacc tagaactcat ccgtgaaaac acgattgacc
     8041 tgctaggaat caattactat cagcctcgtc gaatcaaagc aaaagaaact ccaatcaatc
     8101 acgaacatag ccccatgcca gatgattatt ttgataatta cgacatgccc aataaaaaaa
     8161 tgaatccata tcgtggatgg gaaatttacg aaaaaggaat ctatgatatt ttaacgaata
     8221 caagagaaaa ctatggtaat atcaaatgct atatttctga aaatgggatg ggggtcgaag
     8281 gagaagaacg atttgttaac agcgaaggaa ctattgaaga tgattaccgg attgagtttg
     8341 ttacggatca tttgaaatac gtccatcaag caatccaaga aggaaccaat tgtgtgggtt
     8401 accacatgtg gacatgtatg gacaactggt cttggacaaa tgcttataag aatcgctatg
     8461 gctttatcgc tgttgatttg gcacaagacg gtaaacggac gatcaaaaaa tcaggtcgct
     8521 ggtttaaaac ggtctctgaa aaaaacggat ttgatgcctg atattttttg ataaaacgtt
     8581 cacaaaatgt ttgttctaac actgtaatcg tgctacacta acagtgaagg aggcgtttac
     8641 aatggtagat acttatcgta atattttagt agcaattgat ggttctgaaa aggcagaaaa
     8701 agcatttctt gaggcaatca cgattgccaa acgaaatcag gcaacgttgc acatcctgta
     8761 tgtcaatgaa gtaacaggca attactttgg tgattttgca tttgttacaa caagccttca
     8821 ggaagaattg gatgaggttg cggaaaacca gatgaaagaa catcgaaact tggcaattga
     8881 aaaaggcttg acagatatcg agacatatgt tctttacggt tatccaaaga cactgattgc
     8941 taatttccat gaatcgaaag aaccaatcga tctgattgtc atgggggcga caggtctgaa
     9001 tgcggtagaa cgtgcactag taggttccac tacttcctat gtagtcaacc acgcatcatg
     9061 taacgtcatg gttgtaaaat aaataaatta agggaacaga aagcaaaaaa gcataacgct
     9121 tcttttgctt tctgttcctt taattttttg taaaaaatta ctttacctga tgaagtaatc
     9181 atgctattct aattacaacg acagatggag taatatggag gaaagaaaat gatttcaagt
     9241 gatggaatac gcggatacaa tgatgcgatt attttatcga tccttaacaa aaacgattct
     9301 tatggatatg aaatttctaa aacgattcgt gagaggacaa atgattccta tgtgatcaaa
     9361 gagacaacac tttactccgt ttttgcccgt ttagaaaaga atcaactgat tgtttcgtat
     9421 cctggagaag tgactcatgg aaaaaagcgg acatattata aaatcactga aatagggcgt
     9481 aatcttttag aagaaaaaaa gcaagagtgg ctgacgacga aagacgtagt cgatcaattt
     9541 ttggagggaa attaaatgga tacaatccgt aattatttag acagtctttt tatcggagta
     9601 cctcaaagta ccgagataga taagctgaaa actgatttgt tggcaaatat ggaagaccat
     9661 tatcatgaat tgatgggaga aggaaaaaat gaacaggagg ccatcggtac agtaatttcg
     9721 acatttggtt caatcgatga attattagaa gaactagatg tcgaaaaaaa acatcaagct
     9781 gacgagacgg aaacaaacac agcttctatt tatttaagcg aagcagaaaa ctactggaaa
     9841 gaatacagag cggcaagtct ccaagtggca tcaggtgttc tattcattag cttatctttt
     9901 gcaagttttc ttttcttttg ttcagcaggg tatgtgttca tgggtatttc ttgtctgatt
     9961 ttcggtatag cattagctgt cggttttttt attgcttctg gtatgaaaat cacacgttta
    10021 aatcactttt tgcaccatcg gaaaatacct gaaaaagtat tagcagaagc aaaagaaaaa
    10081 gaagaagagt atcagcgaag ttttggcttc tcactgattg caggaattgg attatgtatt
    10141 ttttcacttt tcccactttt ggcttcttta atgtggtata tggatggtag tatcggtgcc
    10201 tctatatttt ttgttacggt aggaacggga gtcttcttga tcatttatgg cagtctggtc
    10261 cgtcattctt atcgtcaatt cactcaaagt gcttattact ggtgaatgta ttcagatttg
    10321 taaaaatatt ttatttattg cttacccatg taaaatcgtt atagacagat ttcagttgac
    10381 ttctgcgcca ttgtacaggg ataaaaagac gcatactatc ttcattgaat ccgactaata
    10441 atttctttcc gtcagtaatg atgggacgtt gtaacaaagt aaaatgcgag acgatcagat
    10501 cgacaagctc tgaggtcgta cattggtcga tttgatcttt caaattttta taatcaatcg
    10561 agcgtttagc taatagatcg tcaaatccgt tttctgttaa tgacaataaa taaaatatct
    10621 ctttccttgt taaaggctgt ttaggtgtga aaattcgttc tctgtaaggc atttgatggt
    10681 ctttcagcca gtttgccatc agatggtaac tatgtgtgcg agaagaatag atcgtaagca
    10741 taaaaaaact ccttaaatag tccattaatt tgttagatct gttgagataa ataataggta
    10801 aggagctgtg cataagcatt gatcaaaaca acccaaacat cattagaaat aactttctaa
    10861 agtcttaaac ttgcgacgag aaacaactag actaatagaa aaaatgtctt agccatttgg
    10921 cttcctgttt gtttttttgc ttatgctgca gctcctcggg aaagggttct aacaatttga
    10981 agaaggttga tgattgatct agtttaaatt gtgtgaaatt tgaaatctgg tgtttttact
    11041 agatgaatca cctaacaact atgattataa cttatagaac ttctgttttg tacttggttt
    11101 tgttatagtt gttataaagt tttattttat tacagaacat ttttaattaa
//
LOCUS       DAPBCF010000073        11134 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.075, whole genome shotgun sequence.
ACCESSION   DAPBCF010000073 DAPBCF010000000
VERSION     DAPBCF010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11134
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.075"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            117..353
                     /gene="secG"
                     /locus_tag="RD508_002492"
     CDS             117..353
                     /gene="secG"
                     /locus_tag="RD508_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDT7737023.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            456..1211
                     /locus_tag="RD508_002493"
     CDS             456..1211
                     /locus_tag="RD508_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDT7737024.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            1214..3571
                     /gene="rnr"
                     /locus_tag="RD508_002494"
     CDS             1214..3571
                     /gene="rnr"
                     /locus_tag="RD508_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDT7737025.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            3593..4057
                     /gene="smpB"
                     /locus_tag="RD508_002495"
     CDS             3593..4057
                     /gene="smpB"
                     /locus_tag="RD508_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDT7737026.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            4359..5078
                     /gene="atpB"
                     /locus_tag="RD508_002496"
     CDS             4359..5078
                     /gene="atpB"
                     /locus_tag="RD508_002496"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDT7737027.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMVISLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            5131..5346
                     /gene="atpE"
                     /locus_tag="RD508_002497"
     CDS             5131..5346
                     /gene="atpE"
                     /locus_tag="RD508_002497"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HDT7737028.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVVALILVFGV"
     gene            5437..5961
                     /gene="atpF"
                     /locus_tag="RD508_002498"
     CDS             5437..5961
                     /gene="atpF"
                     /locus_tag="RD508_002498"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDT7737029.1"
                     /translation="MLNQLAIAEVGNAMLGNVIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            5948..6490
                     /locus_tag="RD508_002499"
     CDS             5948..6490
                     /locus_tag="RD508_002499"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDT7737030.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYAYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMNYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLENMRNQLNR"
     gene            6513..8069
                     /locus_tag="RD508_002500"
     CDS             6513..8069
                     /locus_tag="RD508_002500"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDT7737031.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            8083..8985
                     /locus_tag="RD508_002501"
     CDS             8083..8985
                     /locus_tag="RD508_002501"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HDT7737032.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            9008..10414
                     /gene="atpD"
                     /locus_tag="RD508_002502"
     CDS             9008..10414
                     /gene="atpD"
                     /locus_tag="RD508_002502"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDT7737033.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            10428..10850
                     /locus_tag="RD508_002503"
     CDS             10428..10850
                     /locus_tag="RD508_002503"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HDT7737034.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         3701 a         1966 c         2450 g         3017 t
ORIGIN      
        1 aataacagct gaaagttttg aactttcagc tgttattcca tttatataga gttgtcacgg
       61 acttttatct atgataaagt taaagagacg atatcttttg ggaaggaggc tgcgatatgt
      121 ataatttaat tttgggaatc gtgatcgttt tatcgattgt tatggtcatt gcgattatga
      181 tgcagccaag caagcaaaat agtgcagcga gtgcatttac cggcggtgcg gatcaactat
      241 tcggcaaaca aaaagctcgc ggctttgaag ctgtcatgca gcgatcaact gcagttatgg
      301 gagctatctg gatgatctta ttatttgtcc tagcatattt atcttcgaag tagttgaata
      361 agcctctcgc aaaacggcgg gcggcttttt ttattgcaaa gagaacgctt aagaagaagt
      421 tatgaaagaa actatggtaa aatgaggcga aagaggtgag acgagtgaga caattaccaa
      481 aaccccttta tgcaaaacat ggaaagcgag cggttttgct gcttcacgct tactcaggaa
      541 gtccaaacga tgttcgaatg ctcgcacgat ttttggaaaa agcagattat acagtttatg
      601 cgccgctttt taaaggacac ggaacaatgg agccatatga tatcttgcaa gaaaaagcag
      661 aaagctggtg ggcagacact aaaaaagcca tccatttttt acagtctgag cagttttctg
      721 atattgccgt attaggatta tcaatgggcg gcatctttgc tgtacgagca ctagaagaag
      781 aatcagtgat tggcggcggt tttttctgtt cgcctttgtc tcctgtaaaa acaaacgtgc
      841 ctgaaaactt tgaaaaatac gtacgtcaag tgctgaagac agcaggtaaa tcagagaaag
      901 aaatcaatga aaaagcagtt gcttaccgct cgttagctga acaacaatta atggatatac
      961 aagatcaggc agcaatcgta gaaagtaggt tgtcagatat ccaacagccg atatttttag
     1021 ctcaagctgg gaaagatgaa atgatcgacc ctaatggcgt atttgaaact gcacgcaagt
     1081 tgagccgtca gcgagtgaca cttcaatggt atcctgaaag tggtcatgtg attacagttg
     1141 gtacagcaag acgcgaatta gaaaaagacg tcttggaatt tttagaaaaa ttaccttgga
     1201 atgaggaata aatatgacaa aagaaacgat aaaagagaaa attctctttt tcatggaaag
     1261 cagtcgcaaa cgcagttttt ctatggaaga aatcgctgaa ggtttagggt tccaaaaaag
     1321 cgatgatttt aaattactag tacaaacgat tgctcaaatg gaaagagaac agagtatagt
     1381 tttcaataaa aaaggaaaag tgaaacttcc tttaaaacca atcttgatcg aaggaacatt
     1441 tcgagcaaat gaacgaggat ttggatttgt aacgattgat cccgaagaag atgacatcta
     1501 tatcccaaaa gaagcgactg gttttgcaat ggatggagac accgtagcaa tcgatatcat
     1561 gaagcgagca aatacagata tggatcgcgg agcagagggg aaagtagtcg agattcgaga
     1621 ccgggcgact actcagttag caggggaatt cgttgcttat tcagaagaag aaatacaaga
     1681 aacagatctt tacggcgttg ttatcccgaa agatagaaag ctcaaccaat ttaaagtata
     1741 tgcagcagca gagggagttc gtccagttga cggaagtatt gtgctgatcg aactgaccca
     1801 ttaccctgaa aaagggtatg cgactagttt agaagggata atcaagcaag tgattggtca
     1861 taagaatgac cctggcatgg atatcctctc aattgtcgtg gctaatggta tccctacgaa
     1921 atttcctgat gatgtattgt ctgaagcaga tgaagttcca gatcaaatca gcgaaaagga
     1981 tataactgga cgtagagatt taagaaatca gctcattgtt acgattgatg gagaagatgc
     2041 aaaagatcta gatgatgcag ttacggttaa aaaattagat aacggtaatt attttcttgg
     2101 agtacacatt gcagatgttt cttactatgt gacacaaggc agtcaattgg acagagaagc
     2161 atatgaaaga gggacaagtg tatatttgac tgatcgagta attccgatga tcccgcaacg
     2221 tttatcgaat ggtatctgtt cactgaatcc ccatgttcca aggctgacca tgagttgcga
     2281 aatggagatt gatccaaatg gacaagtagt ctctcatgat attttcccaa gtgtgatcca
     2341 aacaacagaa cggatgacct acacagctgt caatcaaatc ttagaagatc aagacgaaga
     2401 aacgatgcaa cgctatgctc agctcgtacc tatgttccaa gaaatgggtg aattgcaccg
     2461 aatccttgaa acgatgcgaa tcaaacgtgg cgcgatttct tttgaggatc gcgaagcgaa
     2521 aatccttgtt gatgctgaag gacacccaaa tgacatccag ctaagaagca gaggaattgg
     2581 tgaacgcttg atcgaatctt tcatgcttgc ggccaatgaa acggtagctg aacattataa
     2641 taaattaaat ctgccgttta tttaccgaat acatgaacag ccaaaagaag aaaaaatgca
     2701 gcgcttcttt gattttgctt cagctttggg cattctggtc cgaggaacga aaggaacgat
     2761 cacaccaaaa gatttacagc atgtgatcga aggagtagaa gacaaaccag aagctgcagt
     2821 tatcaatact atgttgctaa gaagcatgca acaagcacgc tattcagaag acaattttgg
     2881 gcattatggc ttagcggcag attactacac acactttaca tctcctattc gacgctatcc
     2941 cgatctaatc gtccatcgtc tgatccgttc ttacagtgaa gataaaagtg aaagcaatca
     3001 aagttcgtgg gctgcggaac ttcctgaaat tgcagatcat agttctaaga tggaacgtcg
     3061 tgcagtagaa acagaacgtg aagtagattc catgaagaaa gcagaattca tgatggacaa
     3121 agtgggagaa gaattcgatg ggatcatcag ctctgttgtg aaattcggcc tgtttatcga
     3181 actgccgaat acagtagagg gattgatcca tatcaatgaa ttgaaacagg actacttcca
     3241 ttttgttgaa aatcatttag ctcttgtagg tgaaagaact ggtctgactt ttaaaatcgg
     3301 acagaaagtg cgagtaaaag tagtcaaagc tgatccagat gaacgagcag tagattttga
     3361 acttgtatcc gcagaagagg ttacagcgtt ggaacggcca aaaacacgaa atggaaaatc
     3421 aggaaaacgc gaaggaaaac aagcaggaaa acgcccagaa agaaatggca agaagaacaa
     3481 acgatatagc gatagtaagc aaacgttcgg taagaaaaaa gggaagaagc cattttacaa
     3541 aggtgttaaa aaaaagaaaa agaaaaaata aaatgagttg gaggaaacag ctatgccaaa
     3601 aggcgaggga aaattaattg cacaaaacaa gaaagctcgc catgattatt cgatcatcga
     3661 cacgatggaa gcagggatgg tcttgcaagg aaccgagatc aagtcgatac gaaacagccg
     3721 gatcaatcta aaagatggat ttattcgcgt ccgcaacgga gaagctttct tgcataatgt
     3781 tcatatcagt ccttatgaac aaggaaatat ttttaatcat gatccgttgc gcacgagaaa
     3841 gttattatta cacaaaaaac aaatcatccg gcttgaaaat gaattgaaaa atactggaat
     3901 cactgttgtt cctttaaaag tctatattcg taacggctat gccaaggtat tgattggtct
     3961 ggcgaaaggg aaaaaatctt atgataaacg ggaagatttg aaacgaaaag atatcgatcg
     4021 acaaattgat cgaacattaa aaaatttctc tagataattt cattatcctt tttcgcatat
     4081 tcggtgcttt tgcttttact taatgataaa atttgttagc atttaatctg ataaaacatg
     4141 attatcatag gttttttctt agatcaggag caccgtgtat aaagaaaaat tcgcttcgtt
     4201 tttgactgaa ataaaaaagt gtctaatttt catgaaaatg ttttgaattt tctgtttcat
     4261 ggtggtatga taccgtgtgg ttagaaaccg attggaaaaa accagatacg cacatgaatt
     4321 gattttatgt gaatttcggg gaaaagaggt gaaatggatt ggatgaacgc tcgctaacgt
     4381 tccacattgg accaatttgg tttgatggta cagtttgtat aatggtgtta ctgacctgtt
     4441 tgattgtttt cttcttagct tactttttta caagaaatct taagttgaaa ccaacaggca
     4501 aacaaaatgc gatagaatgg gtcattgatt ttagtcgagg aatcgtaaca gataatctgc
     4561 ctagaaaaga attgagcaat ttccatttgt tggcatttac attgttttta tttgtttttg
     4621 ttgcaaacaa catcggttta gtaacaaaaa tcgttttacc taacgaaaca acactttgga
     4681 aaagcccgac agcagacccg tttgttactt taactttggc atttataatg atcttactta
     4741 ctcacttatt tggggtgaaa aagttaggct tcaaaggata tttcgtaaat tcgttcttga
     4801 aaccatatag ttttatgttt ccgatgaaac tgattgaaga atttacaaac ttattaacac
     4861 ttgctttacg tctttatggg aatatttatg cgggggaagt tttgctaacc ttgattgcaa
     4921 aaatggtaat aagcttaggc tggttctcat tgccgttagc aattccatta gagatggtct
     4981 ggatcgcatt ctccttgttt atcggaagca tccaagcatt tgtcttcgtt actttatcta
     5041 tggtttatat gagccataag attgaagtgg aagaataata ttcgttttaa aaacaaacta
     5101 ctatttatct aatttaggag gaaaacaatt atgaattata tcgcagcagc aatcgcaatc
     5161 atgggagcag caatcggagc cggttatggt aacggtcaag ttatctctaa aacaatcgaa
     5221 tcaatggctc gccaacctga aatgtctggt caattccgta caacaatgtt tatcggggta
     5281 gctctagtcg aagctgttcc tatcttaggg gtagttgtcg ccttgattct agtttttggt
     5341 gtttaattga atcagtatta aggcagaaac aatttggttt gttactgctt ttttacatga
     5401 aaactagaag tacttcaaag aaaggaaggc tcgcctatgc tgaatcaatt ggcaattgca
     5461 gaagttggca atgcgatgtt aggaaatgtc atcgttgtca gcggctcatt tttgatacta
     5521 ctggctctct tgaagcattt tgcttgggga ccaatcagcg atattttgaa aaaacgtgaa
     5581 gacaagatcg ccaatgattt ggattctgca gaacaatctc gcatcaactc agcgaaaatg
     5641 gaacaagaac gcgaacaaca attgttagcc tctcgttctg atgcagctga tatcatcaaa
     5701 aatgcgaaag aaagtggaga attaagccgc caaaatattt tgaaggatgc tcaagaagaa
     5761 gcagctcgtc taaaaagtaa agcccaagct gatatcactg tagaacgtga ttcagcgctg
     5821 aactctgtaa aagacgatgt tgcagaacta tctcttcaaa tcgcggaaaa aatcttgaac
     5881 aaagaattat ctccagaaat gcacgaatca ttaatcaatc aatatatcga aggtctaggt
     5941 tcttcaaatg aaactagata aatatacagt aggaagacgt tacgggaaag ctttatttga
     6001 actggcgatc gattcaaatc aagcagaaga aatctatcaa gatctcgtaa gcttacgtca
     6061 aatctatgaa caagtacctg gattaggtaa tatgttaagt gatgttcgtc tagaacctca
     6121 tgaaaaacga gaaatcatgg acaagcttgt tagtggctat gatggaatcg ttaaaaactt
     6181 tttagaagtt gtttatgcgt ataaccgaat ggatgatctt ttgttcatga tcgaagaata
     6241 tgaacgtcga tatgatgaac atcaaggttt gctgttggga agtgtcacaa cagcagttcc
     6301 actttcagac gaacaacgaa tacaattaga aaagaatgtt gcaaaaacaa tgaactatca
     6361 atcagtcgaa ttaaaacaaa tcgttgattc ttctattatt ggtggcgcga ttgttgaagc
     6421 taaccatcga gtaatcgacg gaagcattcg cacgcaatta gaaaatatgc gtaatcaatt
     6481 aaatagatag tacaaagagg taggtgaatc gaatggccat caaagcagaa gaaattagtg
     6541 ccttgattaa agaacaaatt gaaaattatc aaaacgtgct ttcagtcgaa gaaatcggta
     6601 ccgtaactta tgtaggtgac gggatcgctc gtgcacatgg tttagaaaac gcgatgagtg
     6661 gtgagttgct tgaattttca aatggctcat acggaatggc gcaaaactta gaatcaaatg
     6721 atgtaggtat cattatcctt ggcgatttcg agtccattcg tgaaggagat aaagtaaaac
     6781 gaacaggaaa gatcatggaa gttccagttg gagaggcctt gatcggacgg gtagttaatc
     6841 cgctaggtca gccaatcgac ggactaggtg aaatcgttac tgacaaagct cgtccagtag
     6901 aagcaatggc accaggcgtt atgcaacgta aatctgttaa cgaaccaatg caaacaggtc
     6961 taaaagcaat cgacgctctt gtaccaatcg gacgtggcca acgtgaatta gttatcggtg
     7021 accgtaaaac agggaaaact tctattgcga tcgatacgat catcaaccaa aaaggtcaag
     7081 atatgatctg tatctatgta gcaatcggac aaaaagattc tacagttcgt acacaagttg
     7141 aaacattgaa aaaatatggc gcaatggatt acacaatcgt tgtgaatgcc ggtgcgtctc
     7201 aaccagcgcc gttgctttat atcgcaccat atgctggtac tgcaatgggt gaagagttca
     7261 tgtacaacgg taaacatgtc ttgatcattt ttgatgatct ttcaaaacaa gctgttgctt
     7321 atcgtgaact ttccttgcta cttcgccgtc caccaggtcg tgaagcttat ccaggggatg
     7381 ttttctactt acactcacgc ttattggaac gtgcagcaaa attaagtgat gatttaggtg
     7441 gcggttcaat gactgcctta ccatttgttg aaacacaagc tggagatatc tctgcttata
     7501 tcccaacaaa cgttatttcg atcactgatg gacaaatctt cttagaaagc gacttgttct
     7561 acgcaggtac tcgtccagcg gttgatgccg gactatctgt atctcgtgta gggggttctg
     7621 cgcaaatcaa agcaatgaaa aaagttgctg ggactttacg tctagactta gcaagttacc
     7681 gtgaattaga agcatttaca caattcggtt ctgacttgga tgcagcaaca caagcaaaac
     7741 taaatcgtgg acgccgtaca gtagaaatct tgaaacaaaa attgcatgca ccgctagctg
     7801 ttgaaaaaca agtagtgatt ttgtatgctt tgacacatgg attcttagat agtatccctg
     7861 tagacagtat tttagacttc gaacatgaat tattcgaata tctggatacc aatcattcag
     7921 atatctttga aacaatccgt acaacaaaag atcttccaga agaagaagcg ttgaacagtg
     7981 cgattcagga atataaagac atgttcttag ctacaaaagg aaataattcc tctacagaag
     8041 ataaattgaa atccattcaa aatgcatagt gaggtgagat gaatgggtgc ttcattaaat
     8101 gaaatcaaga cacgtatcgc ttcaacgaaa aaaacgagcc aaatcacgcg ggcaatgcag
     8161 atggtgtctg cttctaagtt gacaaaatct gaagcttctt cacagaagtt tcaggtttat
     8221 gcaacaaaag taagagaaat cgttacgcat ttgactgcta ctcagttaaa tgatattgcc
     8281 tcagaaaatc ctagagggga tatcaattac aacagcatgc tgctcagccg tcctgttaag
     8341 aaaactggtt atatcgtcat cactgcagat ggcggtttag tcggtggata taacagctcg
     8401 atattgaaac aaacgatgtc tattttagaa gaagaccacc aatcacccga tgattacgtg
     8461 atgatcgcaa ttggcggaac tggtgcagac ttctttaaag cacgcggtat caatctagca
     8521 tatgagctgc gcaatctatc tgatcagcca agctttgatg aagtccgcaa aatcgtaaat
     8581 atggcaacaa ctatgtacca aaacgaagta ttcgatgaat tatacgtatg ttataaccat
     8641 catatcaatt cgctaactag tcagtttcgt gtagaaaaaa tgctgccaat ctcagactta
     8701 gatccagaag aagcaactac tttcgaacaa gaatatattt ttgaaccttc aaaagaagaa
     8761 atcttgtctc agttattgcc tcagtatgct gaaagtttga tctacggtgc gatcgttgac
     8821 gccaaaacag cagaacatgc tgctggtatg acagcaatga aaacagcaac tgataatgct
     8881 gctaatatca ttgatgagct gacggtttct tataaccgtg caagacaagg ggctattacc
     8941 caagaaatta ccgaaattgt tgccggagct tcggcactag aatagtattg agattggagg
     9001 aaaaaagatg agttcaggca agattgttca agtaatcggt cccgttgtcg acgtggaatt
     9061 ttctttagac caatccttac cagatatcaa caacgcatta gttgtttata aaaatgacga
     9121 aaataaatca aaagttgttc ttgaagcagc gttagaatta ggggacggag tgatccggac
     9181 cattgcgatg gaatcaacag atggtttaca aagaggaatg gaagtcattg atacaggcaa
     9241 agcaatctct gttcctgtag gtaaagaaac attaggtcgc gtattcaacg tactaggaga
     9301 tacgatcgat ttagaaacac ctttcccaga agatgcggaa agaagcgaaa ttcataaaaa
     9361 agcaccagcc tttgacgaat taagtacaag tacagaaatt ttggaaacag ggatcaaagt
     9421 tatcgatttg cttgccccat atttaaaagg tgggaaagtc ggactattcg gtggtgccgg
     9481 tgttggtaaa accgtactga tccaagaact gatccataat atcgcccaag aacatggtgg
     9541 tatttctgta tttactggtg taggtgaacg tactcgtgaa ggtaatgact tgtattatga
     9601 aatgaaagat tcaggagtta tcgaaaaaac agccatggtg ttcggacaaa tgaacgaacc
     9661 accaggtgca cgtatgcgtg ttgctttgac tggtttgacg attgcggaat atttccgtga
     9721 tgtagaaggt caagatgtac tgttgtttat cgacaacatt ttccgtttca ctcaagctgg
     9781 atctgaagta tcagccttgt taggacggat gccttctgcg gttggttatc aaccaacatt
     9841 ggcaacagaa atgggtcaat tgcaagaacg tatcacatct acgaaaaaag gttcgatcac
     9901 atcgatccaa gcaatctatg tgccagccga tgactacact gacccggcgc cggcaacagc
     9961 attcgcccat ttggatgcga caaccaactt ggaacgtaaa ttaacagaac aagggattta
    10021 tccagcggta gatccattgg cttcttcttc aagtgcttta gcacctgaaa tcgtgggaga
    10081 agaacattat aaagtagcaa cagaagtcca acacgtattg caacgatatc gtgaattaca
    10141 agatatcatt gctatcttag gtatggatga attatccgat caagaaaaag tgttagtttc
    10201 tcgtgcccgc agagtccaat tcttcttgtc acaaaacttt aacgtggctg aacaatttac
    10261 tggtcttcca ggttcatatg tccctgtaga agaaacagtg aaaggattcc gcgaaatctt
    10321 ggaaggcaaa tacgatgatc ttcctgaaga agctttccga agtgttggcc gaatcgaaga
    10381 cgtcgtagaa aaagcgaaaa cactaggcta ctagaaaggg gtgccccatg gatcaatatt
    10441 taacagtaaa tgtggtaact cctgccggtt tggtctatga tcaccatgca gctatcgtcg
    10501 ttgcacgtac gacagctggt gagcttggga ttttgcctaa acatgcacca atcatcgttc
    10561 cattgacgat tgatgaagtt cgtgtaaaac gaacagattc agatacccac gtcgattgga
    10621 tcgctgttaa tggcggaatc atggaagttc gtgataatgt tgtttcaatc gttgctgata
    10681 gtgcggaacg tgaacgtgat atcgatgtat ctcgtgcgga acgtgcaaaa caacgcgcag
    10741 aacgccaaat cgaagaagca aaagcaaaac aagatacgaa cgaattgaaa cgggcaactg
    10801 ttgcgttgca ccgagcaatc aatcgtatca aagtatctaa gcactcataa aatgagatgc
    10861 ggatgtttat ccgtgtttaa gaacagtaaa aagaggttat gacagaagtg gtcagcttca
    10921 agacataaga aggaatttac gaaaattgct tctcaaattt ttgtgaaatc tcagcttatt
    10981 tttcgaagaa gctacttctg gaacaccgta tatcagaggt tgtaaaatca gcgttttgtc
    11041 ctgagtatta gagaaacaaa tggaaaatag ttcctcatat tttgccgttt tttgagctaa
    11101 taccgagggt cagatgattg aacaccgttt attt
//
LOCUS       DAPBCF010000074        10956 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.076, whole genome shotgun sequence.
ACCESSION   DAPBCF010000074 DAPBCF010000000
VERSION     DAPBCF010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.076"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..154
                     /locus_tag="RD508_002504"
     CDS             <1..154
                     /locus_tag="RD508_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HDT7737035.1"
                     /translation="SLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTL
                     RYSLGY"
     gene            complement(235..1218)
                     /gene="istA"
                     /locus_tag="RD508_002505"
                     /pseudo
     CDS             complement(235..1218)
                     /gene="istA"
                     /locus_tag="RD508_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311512.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(1613..2455)
                     /locus_tag="RD508_002506"
     CDS             complement(1613..2455)
                     /locus_tag="RD508_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDT7737036.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            2780..3196
                     /locus_tag="RD508_002507"
     CDS             2780..3196
                     /locus_tag="RD508_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDT7737037.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3193..3663
                     /locus_tag="RD508_002508"
     CDS             3193..3663
                     /locus_tag="RD508_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7737038.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3677..4450
                     /locus_tag="RD508_002509"
     CDS             3677..4450
                     /locus_tag="RD508_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7737039.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4464..5276
                     /locus_tag="RD508_002510"
     CDS             4464..5276
                     /locus_tag="RD508_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7737040.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5330..6295
                     /locus_tag="RD508_002511"
     CDS             5330..6295
                     /locus_tag="RD508_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7737041.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6432..9155
                     /locus_tag="RD508_002512"
     CDS             6432..9155
                     /locus_tag="RD508_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7737042.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLYSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIINFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            9168..9800
                     /locus_tag="RD508_002513"
     CDS             9168..9800
                     /locus_tag="RD508_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7737043.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            10005..10232
                     /locus_tag="RD508_002514"
     CDS             10005..10232
                     /locus_tag="RD508_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HDT7737044.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10301..10567
                     /locus_tag="RD508_002515"
     CDS             10301..10567
                     /locus_tag="RD508_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HDT7737045.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10557..10826
                     /locus_tag="RD508_002516"
     CDS             10557..10826
                     /locus_tag="RD508_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDT7737046.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
BASE COUNT         3635 a         1742 c         2142 g         3437 t
ORIGIN      
        1 ttccttagaa aaattaggtt gtcaaaattt caactcacgt tctgttaaag ggctagagag
       61 tagatttgaa agcatattac tggcttacag tgttctatta agtcgagcac aacgacgttt
      121 tgaaggaact ttgagatatt ctttaggata ttaaaattaa ctagcaccac gggtaaaata
      181 aatagttttt ctatcaagta tattgaacta cgataaattt gttattttgt tttgtttaat
      241 ttcgttgtac ttattggctt tgacttcgat ttctttaaat actgggtaat cggtgtccgg
      301 caaagctagc aaatctgttt tttctgtgtt ccatagatca ttgataatga catgtttttc
      361 gtaatggatt cgctctcgat cgtgtgacag ctccaccgct aatgcctcgt tgaaactggc
      421 gaaatccttc ataatcggtg tagatgaaaa gaagttgtac cgtacatagc cgactttgtt
      481 ttccatacta cctttctcgt ttccgctacg tggattgcac acctgtgtct caaaaccata
      541 gtgcatagaa aatcggagga aaccgtcagt cagcaccgct tgttcagtct ttgtttttgt
      601 ctaagtaacg gccgttgaca tattatcaat ccgtattttc cgaggaacgc cacctgattg
      661 gctgaagagt tctttcatgc cttccaacaa acattcttga ttctcggcgg ggagtacaac
      721 ggcgaatcct gcattactaa aagggaaagt catcactaat accttcacat ctttaaacgc
      781 tccatcgtga caaacttcca tcgtaccaaa atcaagttgc gcttctgctg gcgggtgttc
      841 aagacgctca aagccttggt cttccagtgt ttccaagtag tgtgtcgctt tccaatcttg
      901 aatgaataca cagactgttc ggtaggatcc tggaaagcca tcggctttta aagcagtagt
      961 cattgcttca gcagtcctac gctttttatt tggcagctta gcatcttctg aaagccatag
     1021 ggaaacgatg cctccccact tttctgtata catcatacca gtctttttgc gtgctttagg
     1081 ttgcggcagc aaatcatcat ctgcatattt tttagccgtg cgccaattta catctagctc
     1141 ctttgcaata tgattaatgg atttatcatg attatttcgt aaatttctga tagtattaat
     1201 atcggtcatt gtgagcatac ctttcttacc tccagttaca gtgtcgagac tataacttta
     1261 gaggagtttc aggttgcccg caatggcttt ttatcttaac ttaatcgatt tgcggagttg
     1321 tgtagttttt cgttgcactt gtatgtactt ttattctgcc ataaacagct taatgaatgt
     1381 ccacttgaaa aagtgaataa acgaaataga tgactcgatt taataaggaa gtaaacccac
     1441 acagaaatat aggtgatttt ccttgaatga ccaagatatt gaaagttagt gaaaaaacac
     1501 aaaaaggtag ccctattcac agaaggtctg ccttttgtgt tatcgccagc aaacattaga
     1561 gggggtattt catatagctt ttgtcctctc gacagtccta tcagtttctc ttttaactta
     1621 tctctaagtg ctgtccagtt ttaatagctt ctagcttgtt tcctaactgt gtttttaata
     1681 tgttgaaggc ttttgaacct gtgcagtggc aagtaaggat tttttctact cgtgagtcat
     1741 tcaatttatt tccaattttc attacctctt gctcaggtag acctaaatta tttatataag
     1801 gtatgccaat catatggaag ccaccaatta ggtattttat gggtttagtc ggaaatgttt
     1861 caagagcaat ttccatcata tcgataatgc catgatgact acagccagta aagacaatca
     1921 gaccgtcttc ttgctcaatt acgaccaata attcatctga aaaatcatca taaacaaatt
     1981 tatcatccat ctttttgtat aaattcttgg tggtcgagtt tgctttgcct agggggatga
     2041 tatggaagct cggagcaagt tctgttttcg tttttattgt atgtaaattc tcatgcattt
     2101 taaggatttc atttttagga ataccaacat acagaaacgt ggttaaaatc tttaaataat
     2161 ggggtaaagt tacaccttca gctgtataaa taggggcgtt tcctgatttt aaatatctta
     2221 acccgccggt gtggtcagaa tgaccgtgtg aaataatcac tgcctccaga tcattcaaag
     2281 tttcccccat tttagtcgca ttatagacta attttttatt agcgccagca tcgaagagat
     2341 atttcttccc tgagtagtta attaagagag ataacccatg tccactttta aagttcaaat
     2401 ttattcttga gttttcaaat aaaaccttga tttccactat aacatctcct ttcacatgaa
     2461 cgtgtattca tatattgtag cacattaagt tctatttttt gttgtaatta ccgaaaaaaa
     2521 tattaatgga cgctttttac gctttatttc gtatgtggaa gaaaatttct taggatgtgg
     2581 cgggggattg gggcaaagct aaattccaat tacagtgatc atttaattag acacctttaa
     2641 atacccacac tttcatcaac actataattt agggaaagaa aagtgttggc atgatataga
     2701 aaaaccttta attaacagcg tttcctaaaa ttggcacgca tcttgcttat agaaaagcgt
     2761 aaggatagga ggaatgaaaa tggcaactat aattcttgcc agccatgggg aatttgctca
     2821 aggattaaag caaacagcga caatgattat tggagatagt gtaccaattc atgccttgtc
     2881 agcatttaga gatgaagatg aatctatttt ggtacaaata aaaaaacttt tagccacaat
     2941 agatatagaa gaaacctaca ttttaactga tattctaggt ggtagtgtga ataatgatat
     3001 gctcactatt attaaagagt atgagggatt gcaattaatt actggaatga acttaccttt
     3061 agttatttct attgcaacct ataatggaaa aattggggaa agtgagctag aaaagcttat
     3121 taaagagagt caacaatcag tgattgattg tagaaaatta ttagtagaac aacttactgg
     3181 aggagatgac ctatgattaa gttagtacgt attgaccatc gtttgttgca cggacaggta
     3241 gtattttctt ggagtaaatc attaaatatc aatcgtatta ttattgccaa taaagaggca
     3301 gcgaatgatg aattcaaaaa aatgtctttg aatttatcta aaccgactgg cattaaatta
     3361 acaatttttt cagttgaaca gttactagaa aaaatgccta aaatcgaaac acttaacgaa
     3421 aatatcatgc ttatttttgg taatacaaaa gaaattcgtc aattttgtga agcctatcct
     3481 aaagtacaag aaatcaacta tggagggata atcaaaaaag aaggttccaa gcaatttagt
     3541 aatgccattt tcttgaatga atctgagcaa gaagatgcca aaaaattaaa agctcttggc
     3601 attaaacaat ttattcaaca ggtaccaact tctaaaaaag aagatttgaa tacaatgtta
     3661 taaaggagga atgaaaatgc tcgttcagtc aattggttta gggttaatcg gtgttttttg
     3721 tattttagac tcaaggcttt taggaagaat gaattttgaa cgaccgttga ttgtcagtac
     3781 gcttgttggt ttggtacttg gagacatgga aaaaggatta attgttggag cctctttgga
     3841 attgatgtcc ttaggattag taaatatcgg agctgcttca ccacctgata tgaatatggc
     3901 atcaattatt gctacagcct ttgccatttt atcaaatgcg aatgcagaag cagcattaac
     3961 gattgccatt ccaatttcag tgttaggtca aatactaggt atcttaatgc ggacgatttt
     4021 gtcaaatttg actcacgttg cggatcgctt tatcgaacaa ggaaaattta gccaagcaag
     4081 gagaattcat atactttatg gctcgggatt atatgctctc atgtatttta ttcctatttt
     4141 tctagcaatt tattttggaa cgaatcttgt ttctcagatt gttgatgcga ttcctgagtg
     4201 gctaacaaat ggcttaacgg ttgcaagtaa aattttacca gcatatgggt ttgcgttgtt
     4261 attacaaacg atgttaacga aaaaaatggt gccattttta ttacttggat ttttaattac
     4321 tgcttattct ggattgggaa tcattggtat tgcagccttc gcatgtattg ttgcgtttgt
     4381 catggttcaa gttcaaggta aaaactcaaa tggtaaccaa aatgagccag atccattaga
     4441 tgacttataa ggaggtagat taagtgaaag agaaagatca aaatgcatgg aaatatcggc
     4501 agttcttatg gcgttcatgg gcaattcaag cctcatggaa ctatgaacga caaatgaaca
     4561 tgggttttat gtacggaatt gcaccaattc tagataacat ttacaagaat ccagaagatg
     4621 aagcaatgaa gaaagaagct tacgagcggc atatgatgta ctacaactgt acccctcaaa
     4681 caagtgcatt tgtgttaggg ttaactgctt ctatggagga gcaatactac gaagaccaag
     4741 aaaactttaa tccggaatca atcagtgcag tgaagacttc tctgatggga ccgctatctg
     4801 gtgttggtga ttctttcttt caaggaacga ttcgggtatt agcctttgga ctaggaatta
     4861 atttagccca acaaggtagt attttaggtc caattctagc aatgttaatt tcctttgtac
     4921 cttccttttt agttacttac tatggtggga aaattggcta taacatgggg aataaatact
     4981 tgtctaaact gtatcaagaa ggtttgatgg ataaagtaat gtatgtttgc tccattgtgg
     5041 ggttgatggt cattggttcg atgattgcca gcatgatcgg gattacaaca ccaattcaaa
     5101 tgggtaaagc ttttgtctta caagatgtat tagatagtat tatgccacaa tttttaccat
     5161 taggattaac cttcttcatg tactggttat tgcagaaaaa ggtcaaaaca ggatggatgt
     5221 tggcaatctg tttagtcgga ggaattattt ttagtttgtt aggtatctta caataaggga
     5281 ataaccaata aatttggttg aataatataa ataaggagga attcaattga tgaattcaaa
     5341 agaaattgtt aaagaaatcg tagcgaaaaa agaggtaaaa tcaatcgtat ttgttggctg
     5401 tggcgcttca aaagcggacc tttatcctgc aaagtatttt ctagaccaaa atgcgaagca
     5461 gttacggatt agtcattaca cagccagcga atttaactat gcaacaccag catctgtaga
     5521 tgagtcaact gtcgttattt cagcttcttt aggaggtacg actccagaaa cagttgaagc
     5581 taacgcagta gctaaagaaa aaggtgctac agttattagt ctaacacgaa gcattgactc
     5641 accgttaaca aaagatgcag attatgtaat ttatcatcga tttgcagaga actatgctgc
     5701 taaattagaa aaaacaggct actgtttaga attggcagta gaacttttac atcaagtaga
     5761 aggttatgac cattatgaag caatgcaaga aggatttgct actatctatg atcttgccca
     5821 aaaaagtgca gaatcagctc gtaaagatgc gaagaaattt gctgaacgct ttaaagatga
     5881 aaaagttatt tatgtaatga gtagtggtgc tacacatgaa gtagcatact caacatcaat
     5941 ttgcttgatg atggaaatgc aatggattaa ttctggtacc ttccattcag gagaattttt
     6001 ccacggacca ttcgaaattg tggataaaga cgtaccgttt atattattaa tgaatgatgg
     6061 aaaaactaga aatatagatg ctcgagcatt aactttcctt gaacgctttg atacgaaaac
     6121 agaagttgta gatgccttgg attatggctt gtcttcacat attgctaaag aagtcttaga
     6181 ctactttaac ccattcgtga ttactgcagt atttagagtt tatgcagaag aattgtcaga
     6241 agcaagagaa catccattaa ctaagagacg ttatatgtgg aaactaactt attaaaaaat
     6301 agatcaaact aaataaggtg gcttgagaaa ttaagccacc ttgttttctt caatgtgatt
     6361 ttatacatat ggtaaaataa ctagtacata tggtaaaata actagtacat attgtgaaag
     6421 caggtggcaa gatgcagcga ttaaatgact atctttatca actaacattg cttttgaaat
     6481 ctacgccttc agataattat tcagctcgca gtatttcgca agctctacag ttgaatagaa
     6541 gtacaatcag tagctactta aatgaaggtg ttcgtgaagg gcttttcata aaagtaaaaa
     6601 gttacccggt tttattttta catagaacag ctcttgaaga actacatatc acactgaata
     6661 actccgaaat agaatcaatt gaaagcttgt taacaatttc tcaaaaaccc gcattagatc
     6721 aagtaattgg ctctaaagga agtttgaaag aagcaattga tcaaattaaa acggcagtct
     6781 tatatcctgg aaaagggttg cctttattat tgatcggcgc tagtggatca gggaaaacct
     6841 ttctagcgaa taaaatatat gaatatgcag tagaagaaaa ggtcattcac acatcggcac
     6901 ctttcataga ttataattgt gcacaatatg tgagcaatcc agagttacta tactctgctt
     6961 tatttggcta cacgaaagga gcatttaccg gagcaagcca ggagcatact ggtttgctag
     7021 aaaaagccga tggaggagta ttgtttttag atgaagtgca tcgcttatct gaagaagggc
     7081 aagagaaatt atttacattt atggatacgg gtgaattctc tcctatgggg gataatagta
     7141 ttcggaaaaa agccgatgtt cgattagtct ttgcaacaac agaaaatata tatacgactt
     7201 tcttaccaac ttttcttagg agattgccag ttattgttaa tctacctaga tttcaacaac
     7261 gtccgtcgtt tgaacgtctg tcattgattg atgaattttt tgtttctgag agccaaattt
     7321 tagctaagga actatctgtt tctgatgcat tgattcattt cttaatgaat agtgattttg
     7381 aaggtaacgt ggggaatatt aaaaatatta tcaagtatgc ttgcggaaac gcatatatcc
     7441 accagaagag tcagcaaaca attcaagtta aattattgga tatgccttta gagtacagtt
     7501 ataaattcaa ggagcaacta aataaaccca gaaagaaaag agcagatcga atctactatc
     7561 cagaagaaac acgacaagtg caactagaaa gaaacaatca gctttttgtt caattttttg
     7621 accaattact tactggattc tctgaagtga ttgaaaataa caaggatatt aaactatttt
     7681 tagaagaaat ggttaccaag gtaacacaag taatggatac gcttattttt caagaggatt
     7741 acgaaaaaga gcagtcttta tacgccattc taaactatca tattcgtcaa agtattgatt
     7801 ttatgcgaga aagctacggg tttgaacaag atggtaaccg ggtagtcgct ttggccaact
     7861 atctatatgt caaggataat caagtgattt ttgaaaatag tcttcaagaa aagaaaacca
     7921 aagatcagct taacgaattt tttgctaatg ttcttgaaac cccttattgg tatgcaaaaa
     7981 aaatcttaag ccttttatct gagtgtttag atcaacctgt gtatgaagag gacattttct
     8041 ttattacgct atatttttat agtttgaatg tcacgaatgt taaaacaggt attaagagta
     8101 ttgtgctagc tcatggttat tctacagcta gtagtatggc gaatgttgcc aaccgtatgc
     8161 tgaataagaa cgtttttcaa gcttatgata tgcctttaga tattacatta gagaaaattg
     8221 aagcaaaatt gattcaattc cttggagatt atcgaacaga ttcaggcttg attttattgg
     8281 tagatatggg ttcactaaac caactaggcg gtttattagt gaatcatcta aatggaccac
     8341 tgttaatcat tgatcatatc aatacaccgt tattattgga agtcggccaa caagtattaa
     8401 acaataaaag tatcaccgaa ataggagcag aaattgaaac aagtcttact ttcaaaaagc
     8461 agttactact tcccaagaaa aagaaaaaga aagccatcat tacttgttgt tatacaggga
     8521 ttggtagtgc gacccagatt caggagattt taacgaaatg cttgaaagat gcagttagag
     8581 aattagtaat tattccgtat gattacaaaa agctgttaga aaacaagaat tttgagactc
     8641 cttttcaatt atacgatgtc atcatgattg taggtacaga agatcccaaa attaatcaga
     8701 ttccatatat tggattagat cgcctgatta atgggggaag cattggcgaa tttgttcatt
     8761 acttggaaaa agagctgact attgaagtga acgatttaca aaaagaatta attatcaatt
     8821 tttcaattag taaaattgtc gaaaatttaa ccattttgga tccagataag gtgctatctt
     8881 ttgtacaaaa agcaattaaa gaattatcga agttattaaa ttttgatttt tctaataatc
     8941 agctgttttt gttgtacctt cactgtagtt gtatgattga acgaattgta cgtaaagaaa
     9001 gtgtggatga gcaagaggac attgaagaat atatgcaagc aaatggagaa ataatggata
     9061 aaattcatag cgcttttttt gagattgaaa gggaatacac aattgaaata ccagatttag
     9121 agttgcgatt attgagcgat attgttcaag gataggagtg aattcgaatg acaatgggag
     9181 taatttttga tatggatggg gtactcatag atagcgagac attttatttt gagagaagaa
     9241 tgaacttctt tcaagaactg gagatagatc caggatcaaa ccagattgat gattatgtgg
     9301 ggaaaacaga agctgcaata tgggaaacat tagttcctga ggacaaatca ttaagagagg
     9361 aactttatcc gaaatatgta gattatcgaa aaacgcatcc aattgatttc gctaaagctt
     9421 tacgaaaaga agtgaaaccg ttacttgact tcctcaagaa gcgggatata ccattggcac
     9481 tggcatcttc ttctccagct gtcgagatag agagtatgct cattcaatgt gaacttactg
     9541 aatatttttc ctttgttata agtggtgagt cattaaaaca aagcaaacca catcccgaaa
     9601 tatatttaaa agcgaaacag caattagact gtgacttctt tattgcagta gaggattcaa
     9661 cgattggtat taaatcagca aaggcagcaa atatctatac ggcggcacta aaacaaccaa
     9721 tgcaaatcga tcagagtgaa gcagacatac aaattgaaag tctacaagaa ctggaacaaa
     9781 ttgttttaga aaaaggttag tgaattaatg gaaataaggc tatatatctg tgctagctat
     9841 tttgactaac caaaaaaact tgctataatt caggtgtagt aaaaggtgct ggtaacacct
     9901 tttacgaaaa tgcttcggca gtgataatgg gattggcttt ttaagttttt tattttgttc
     9961 gcaatcccta aggtcatgtg aatgatccta gggattgcta gaatattttg caacagaacc
    10021 aaaatacgaa tagttatcaa gcagccatat tgactgcggt caatttagga ggggatactg
    10081 atactactgc tgccgtaact ggtgctcttg cgggtattct ttacgggggt gaagtgatcc
    10141 ctgaaaattg gagaaaatcg cttcaaaatg accagcttct taaaacgatc agtcagagat
    10201 tttgcgatac cgtgctatct caaagaattt gaataatgga tatgatgcaa atcttgtttg
    10261 tactaacgtt gtattgacaa aaaggatttt atttagtaca atgttagtac aaatgatgaa
    10321 cggaggtaga atcatgtctc aatcaaccat tacatttagg attcccgacg atgaaaaaga
    10381 actggtatta gaatatgcaa aagcacacaa ttcttcattg accgaacttt atcgaaatgc
    10441 tgtactggat aaaatcgaag atgaaatcga tctacggact ttacggagtg caattgaagt
    10501 ttccaaagag aaaaaagaga gtggtatttc tcaagaggaa atggagaaac tgctaaatga
    10561 attataaagt catctacatg ccgcaagccc agaagcaatt aaaaaaaatg gacagaaacc
    10621 aagctaaaat aattgtcgcc tggatcagaa agaatttaga aaacacgact gacccgcgtc
    10681 agcacggaaa aggtttgact ggaaataaga gtggggaatg gcgctatcga attggaaact
    10741 atcgaatatt ggctaatatt tgtgattctg aaattgaaat ccagatattc tcaattggac
    10801 atagaagtac aatatataaa agataaccgt ttttggaacg aagtagagtt tcgaaagtca
    10861 atgtataatc ttttgaattt tgcataatac cacaggtaga aactacccga tactatcggt
    10921 tggtttctgc ttttttattt ggtcttgaag aagaaa
//
LOCUS       DAPBCF010000075        10927 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.077, whole genome shotgun sequence.
ACCESSION   DAPBCF010000075 DAPBCF010000000
VERSION     DAPBCF010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.077"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            57..1142
                     /locus_tag="RD508_002517"
     CDS             57..1142
                     /locus_tag="RD508_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDT7737047.1"
                     /translation="MSTENQSQKMIIKNWGYKATNVYIEKYYKFPSFLIQNSKYSKMK
                     DSSKIAYMLFKNEFRRALHEKWIDDDGLLYLEFTQADLMDKLNCYQGKVKTILNELET
                     YNLISVVKGEFNPKTKKNEKNKYYLLQPEISADDLFIQNSFDDDLSETIDKSTSSRNA
                     EIARREETAKTLDNTGNAEIARREKTAETLDNTGNAEIAQDYYINKSLDTKRHLKDTE
                     TDQLQNQVLLDNFVEIMKEDSINTFVPEKVLSLIKTFSNTYEEAQQTVTTIHNAKHKA
                     EELEKTVVVYEELESYGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFIEK
                     AIAAKLANEQRETFNELPTVSTENWLE"
     gene            1976..2308
                     /locus_tag="RD508_002518"
     CDS             1976..2308
                     /locus_tag="RD508_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HDT7737048.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKNPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            2899..3228
                     /locus_tag="RD508_002519"
     CDS             2899..3228
                     /locus_tag="RD508_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737049.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDITTIIEGILYGEVDGEISSTKDLLEFLNKNKDRFVVLTDYEE
                     DTTNEKL"
     gene            3215..3556
                     /locus_tag="RD508_002520"
     CDS             3215..3556
                     /locus_tag="RD508_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HDT7737050.1"
                     /translation="MKNYDPNMRRGTHTIKVSFQRWEYKGFVMFRKGGNCKGLSVLSL
                     DEEDLYYQPLTDNPIGFGLLPEDDEGNEWFKMTLKNDEGDELLVEDVWEELGDYIVGL
                     EIVTFVADKEQ"
     gene            3572..3862
                     /locus_tag="RD508_002521"
     CDS             3572..3862
                     /locus_tag="RD508_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737051.1"
                     /translation="MKFFKVKAPFYYALIAAKDKEECMDLYDKVVTDIEDREEFIRCL
                     QELDRNEAIEKDAKTISEETLEPIGMEEATKEIFSIINEQKSCVLSIDSALV"
     gene            4067..4726
                     /locus_tag="RD508_002522"
     CDS             4067..4726
                     /locus_tag="RD508_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737052.1"
                     /translation="MLYILTLLFATIGSSTLIAGIFIVKNMFIVFLGLFFLLFLLFVP
                     RIRGVKSNYEKIIEKELIQSHYWFSQDFRSNMNIEVTIGEIHKNGKVDFIVFVTDDKY
                     LFKKYLIGSYDKEQLTNIQIVNIEFLKLPKIFSALEEESIYFYKLHSKSSKERFYAEG
                     ITTNNQKVEIIASNEDIEIKIDDKTKTTKKLLEITNSYVDIESQGLIVATTRNSKMSK
                     F"
     gene            4809..5063
                     /locus_tag="RD508_002523"
     CDS             4809..5063
                     /locus_tag="RD508_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737053.1"
                     /translation="MKKVFKIFLWIAFITLTIATFFFAVAASYGTILAWFMNGLLFNE
                     NLFAFKWFMFQVICLILTATLRYGVGKLCKKLSMEEDEIQ"
     gene            5369..5584
                     /locus_tag="RD508_002524"
     CDS             5369..5584
                     /locus_tag="RD508_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737054.1"
                     /translation="MAKSVLEPINMDSLTKGKYIQLLARGYTPRDVFRSLAEGTNMKK
                     STLRKEFDYWRIQNGIKELKPVRPVVK"
     gene            5671..5910
                     /locus_tag="RD508_002525"
     CDS             5671..5910
                     /locus_tag="RD508_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737055.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKMMKQKHLKRLSVMQYINDMKIT
                     GKEKACLLGSMKNFEQLRRTYVKTGSNCQLLLEVS"
     gene            6037..6726
                     /locus_tag="RD508_002526"
     CDS             6037..6726
                     /locus_tag="RD508_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HDT7737056.1"
                     /translation="MNKNNKTLFNPYVGVIIVFLLFSYFAYQGYQKDKIAEKVDGVTK
                     TIHIQEQAKTYQDNLTSLTDISKRQLITNQKQALEKDLKGEIAGKLVFSSTGFILPVF
                     QGANSDTLSLGVASTYYLDTEMGNGNYILAGYNVDTPSVLLSDMTDLSEGEEIDLIDA
                     HYKYQYEVSKRGKISDYSQVVQSKENNSFLSLPKAGKKPLLTLLAFQANNMKKCDVIQ
                     CELVNVEKINK"
     gene            6732..7898
                     /locus_tag="RD508_002527"
     CDS             6732..7898
                     /locus_tag="RD508_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HDT7737057.1"
                     /translation="MSHIQELVEKLINKMSAIFLLLLVSILYLIWTVGLNPPTILFIY
                     DNAAQLVTFFVGCLFLLNLYKVKRNDLFFIAAGILFYLFFSFFRSYRGDTFYGDLIVP
                     TIIAIILIVKWTKFTVIDRSLYLVVFYVFLLVTVYRVFTEIPVPEGQSIWNPSNKLSD
                     IWINTNTIGSSLMTLALLITGFASSFGKWYMRLLSLPALILAGATIWVCQSKAALYAL
                     VIFIILEILPKKVFRNTHLSFWMYAAVSVLALPISYFAAMSDKVHLFTGREEIWRKFY
                     ETLGEKTGQIFVGMKPFFFHRGNQILGNHNTYHALVNHYGLIGFVLSIILLLSFLWLL
                     VRKSELTNGQLTFLWAFLAIMCQSFMEETLTTISWVPIVFLMLAMATHQYKTTR"
     gene            7980..8651
                     /locus_tag="RD508_002528"
     CDS             7980..8651
                     /locus_tag="RD508_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HDT7737058.1"
                     /translation="MKKWLFGFLGVALIVVCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVHEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            8704..10680
                     /locus_tag="RD508_002529"
     CDS             8704..10680
                     /locus_tag="RD508_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7737059.1"
                     /translation="MAINRYVKKAGMIVGMLGIIAGCFQGYRAYAEDVTQKTPPERVN
                     ITVHKLMYDQSTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGEEHSFQIGDAVNYQGTIHIPTDIAGGTDGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYDNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGAISAVVYFKKKA"
     gene            10693..>10927
                     /locus_tag="RD508_002530"
     CDS             10693..>10927
                     /locus_tag="RD508_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7737060.1"
                     /translation="MIIRHPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTI"
BASE COUNT         3956 a         1531 c         2128 g         3312 t
ORIGIN      
        1 ttcacttgtt gaaaatcctg aatatataca agtttctaag aagaaggaga aatttaatgt
       61 ctacagaaaa tcaatctcaa aaaatgataa ttaaaaattg gggatataaa gcaacgaatg
      121 tttatattga aaaatattat aaatttccta gttttttaat tcagaattct aaatactcta
      181 aaatgaaaga cagctcaaaa atagcctata tgctttttaa aaatgaattt cgtagagcct
      241 tacatgaaaa atggatcgac gatgatggtc tattatattt ggaatttaca caagcagacc
      301 taatggacaa attaaattgc taccaaggca aagtaaaaac cattttaaac gagttagaaa
      361 catataattt gatttcagtc gtaaaaggag aatttaaccc aaaaacgaaa aaaaatgaaa
      421 aaaataaata ctatttactt caacctgaaa taagtgccga tgatcttttt attcaaaatt
      481 ctttcgatga cgatttaagc gaaactattg ataaatcaac ctcttctcgg aatgcggaaa
      541 tcgcacgtcg agaggaaact gctaaaaccc ttgataacac tggaaatgcg gaaatcgcac
      601 gtcgagaaaa aacagctgaa acccttgata acactggaaa tgcggaaatc gcacaagatt
      661 attatattaa taaatcttta gacactaaaa gacacttaaa agacactgaa acagaccaat
      721 tacaaaatca agttttgcta gataacttcg ttgaaatcat gaaagaagac agcataaaca
      781 catttgtacc agaaaaggta ttaagcttga taaaaacatt ttctaacact tacgaagaag
      841 cccaacaaac cgtcaccaca atacacaacg caaaacataa agccgaggaa cttgagaaga
      901 cggtagttgt gtatgaagaa cttgaatctt acggaattga tgcggataaa ggattatata
      961 tgacgttgct gaaagcttat caaaaacaaa agactgagaa agtaaataat ttgcagaatt
     1021 tgatttttgt gtatgtaaaa aactggttta ttgaaaaagc tattgcggca aagcttgcaa
     1081 acgaacaaag agaaacattt aacgaattac caacagttag tacggaaaat tggctagagt
     1141 agttgataaa aagcgaacac tataaaaatg atcaatttta aattagaact tttttacaat
     1201 tttaatttta ttacaaatgt tacaaataaa tagttattat tccggagttt ttagattaaa
     1261 agtttatgaa aacaatcaca aacgtaggtt ttaatgtcat aatcgttaga tattttagtt
     1321 atttttcatt caaaaaaaca gggaactagt gtttgcatat gtattttttt gagttataat
     1381 aattcatgaa gagaggtaat tcacttattt acccaagctg aaaagcctga tattacttct
     1441 tttcaggcag tgctgctaat attcaattac acttttttgt ataaatttag ttgttttaaa
     1501 tttaattgtc tgctatgctt gtgatgaatt gattttcgtt ctgcactttt ggacgataaa
     1561 tttggacaat tgaaaataca aaaaaaagaa aggccctgtg agactcggaa ggctaccaac
     1621 cttcgtcgac gtccacaggt ggcattaaga tcacccttaa tgcgtttacc tttcagtgtt
     1681 acggtactat ccgcaacgga ttcagtataa cagatattca aaagtgatac cacttttttt
     1741 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcataatgtt
     1801 ataaaaatgt ccgtgtggct ctttgccgta tgatgaacgc tgaaattaga gggaacgcat
     1861 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
     1921 aaaataacaa gaaaaactta ttaaaaatat ttaaagtaag tgggtggatt attttatgtc
     1981 atatacagga attttgagtc tcgaagatat ttgtcactac ggtaaacggt gtaccgctac
     2041 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
     2101 atatataatc cagaaagaca aagtctcaga agaaatgatt tattacattg ggaaacaaaa
     2161 gcaaataatt ttaaagaatc ctatcccttt aaaagagcta tatccaacca tcaaacatgt
     2221 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
     2281 aaaagggatg gggcgtttga tcagctgaat tgatcattct cataacttgt attttatcgt
     2341 ttttcgcttg cttgaaaata ttgtcgagac ttctaaagga acttagaatc attagaaaaa
     2401 taaggagtag acttgatcta tcaacaattc ccttcgggga gtgacggggt aggtttttac
     2461 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgccc ttgtttggat agtggtgaaa
     2521 tgaatttgtg taaataatat gcacagagta aacaagaggg aatttagaag ttagacaagt
     2581 tagaatagcg cctagattaa tcatgagcag ctactaaggg atctaggctt tgacgcaaac
     2641 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaaaaaa ttgtgtcgtg
     2701 tgctgcagta catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac
     2761 cgctgtctac tagggtttct cgtttcggac gccataaacg agtctattta ttttatatat
     2821 ttttgagtga acgaaaaacg ataaaaatat tcgttatgaa gtaaaactaa tttagtagat
     2881 agcaaaggtg gtagaggaat gattcaaaaa tttgcgaaaa tgagtaaaac tgcatggatt
     2941 gaaaagcttg aaaatgactt gagtgtcatg cgattagctc caaagaaatt caaacgagag
     3001 attgcagaaa aagaagcaat tttgtcggta ttgaatgcgg tagacgataa atgtccagta
     3061 aaaattagtt tttcagatat aacaacaatt atcgaaggta ttttatatgg tgaagttgac
     3121 ggagagatat cttctacaaa agatttatta gaatttttga acaaaaataa ggatcgcttt
     3181 gtagtactga ctgattatga ggaggataca acaaatgaaa aattatgatc caaatatgcg
     3241 aaggggaaca catacgatca aagtttcttt tcaacgttgg gagtacaaag ggtttgtgat
     3301 gtttagaaaa ggcggcaatt gcaaaggatt aagcgtctta tcgttagacg aagaagattt
     3361 atattatcaa ccgctgactg ataatccaat cgggtttgga ttacttcctg aagatgatga
     3421 aggtaatgaa tggttcaaaa tgaccctgaa aaatgatgaa ggggacgaat tgttagtgga
     3481 agatgtatgg gaagagttag gtgattacat tgtaggtctt gaaattgtta cttttgtagc
     3541 agataaagaa cagtaaacgg aggaatagac aatgaaattt ttcaaagtaa aagcaccatt
     3601 ttattatgca ttgattgcag caaaggataa agaagagtgt atggatctat acgataaagt
     3661 agtaacagat atcgaagatc gtgaagaatt tatacgttgt ttgcaggaat tagatcgaaa
     3721 tgaagcgatt gaaaaagatg caaaaacaat cagtgaagaa acgttagaac caatcggtat
     3781 ggaagaagct acaaaagaaa tttttagtat tatcaatgaa caaaaatctt gtgtgttaag
     3841 cattgactct gcacttgttt aaggagataa gatgatatga aaataaatac agatagcaca
     3901 gtttctctaa ctacttttcg gttgaggaaa gagtatcaaa aggaattaac caacaaaaaa
     3961 caaggaaaga acagatgatt gtatgaagca atttctcagg atgaaaaaaa taaagactct
     4021 gaatcgatta gatataatgt tggtaaactc tgtaggagat tctgaagtgt tatatatatt
     4081 gactttactt tttgcaacaa ttggaagttc tacacttatt gctggaattt ttattgttaa
     4141 aaatatgttt attgtttttt taggactgtt ttttctatta tttttactgt ttgttccaag
     4201 aatcagagga gtaaaaagta attatgaaaa aattatagag aaagaactca ttcaatctca
     4261 ctattggttt tctcaggatt ttaggtcgaa tatgaatata gaagttacaa taggagaaat
     4321 tcataaaaat ggaaaagtgg attttattgt ttttgtgaca gatgacaaat atctttttaa
     4381 gaaatattta attggatctt atgacaaaga acaactaact aatattcaaa ttgtaaatat
     4441 cgaatttttg aaacttccga aaatttttag tgctttagaa gaagagtcga tttattttta
     4501 caaattacac agtaaatcta gtaaggaaag attttatgca gagggaataa caacaaataa
     4561 tcaaaaagta gaaattattg cttcaaatga ggatatagag ataaaaattg acgataaaac
     4621 taaaacaact aaaaagttat tggagataac caattcttat gtagatatcg aaagtcaggg
     4681 gttgattgtt gcaactacga gaaatagcaa aatgtctaaa ttttaaattt agatcttttg
     4741 aagctctata tctaacagta aaaagtactt taaagatgat gataaataaa aattaaggag
     4801 aataccatgt gaaaaaagta tttaaaatat ttttatggat tgcttttatc actctaacta
     4861 tcgctacttt tttctttgct gtggccgctt cctatggcac aattctcgct tggttcatga
     4921 atgggttgct cttcaatgaa aatttatttg catttaagtg gttcatgttc caagtgatat
     4981 gtcttatatt gacagccaca ctgcgatatg gtgtcggaaa attatgtaaa aagctttcta
     5041 tggaagaaga tgagattcaa tgaatacgat caatgaaggt gaataaatat gtttaactta
     5101 ttacttacag aattccaggc atatcttcat tgttttattt tctactggtt ggtaaaacta
     5161 tctatttttt tattcaacaa agcttttaaa attgagtata aatttgatat aaaagacgtt
     5221 aaaagatact tttttaaaag cttaaatagt tcattttttt atttattgct attgaattta
     5281 atcgtgtgtt ttgcattttt aattatagat ataatatttt attttgttat tactgtaaat
     5341 tgaatgtttt ggataatgga ggtaagaaat ggcaaaatca gttttagaac caataaatat
     5401 ggacagttta actaaaggaa agtacattca attattagct cgaggttata ctccaagaga
     5461 cgtttttcga tccctagcgg aaggaacaaa tatgaaaaaa tcaacgttga gaaaagaatt
     5521 cgactattgg cgaattcaaa atggaattaa agagttaaaa cctgttcgac cagtagtcaa
     5581 atgaaaaata taataactag agtaaatcaa aggcgtatgt aagcataggc ttttttattt
     5641 ttgcaaaaaa caaggaaggt aggaaaactc atgaattatg aagaaatcga aaacagaaaa
     5701 aaagtgtcga aagaaatgga agaaaagttg ctaaaaatga tgaaacaaaa acaccttaaa
     5761 agattatctg tcatgcaata tatcaatgat atgaagataa caggaaaaga gaaagcttgt
     5821 ttgttaggtt caatgaaaaa ctttgaacag ttgaggcgaa cttatgtaaa aacaggttcc
     5881 aattgccaac tattattaga agtttcttga cgattatgat atgaaaatga tcaattatga
     5941 tgtggcattg ttattgaata aaaagaatag taaaatttaa catggtttat cttggttaga
     6001 tgtaggtaaa ttaattcata tatagaaggt agatagatga ataaaaacaa taaaacttta
     6061 tttaatcctt acgtgggcgt aatcattgtt tttcttcttt ttagttattt tgcttatcaa
     6121 ggttatcaaa aggacaaaat cgctgaaaaa gtagatggtg taacaaaaac aatccatatt
     6181 caggaacagg ctaaaaccta tcaagataat ttaaccagtt taacggatat ttctaagaga
     6241 caactgatta ctaatcaaaa acaggcatta gaaaaggatc tcaaaggtga aattgctgga
     6301 aaacttgttt tttcttctac aggatttatt ctccctgttt ttcaaggagc gaatagcgac
     6361 acgcttagtt taggagtagc ttctacttat tatctagata ctgaaatggg aaatggaaat
     6421 tatattcttg ctggttataa cgtagataca ccaagcgttt tattatccga tatgactgat
     6481 ttatctgaag gagaagaaat tgatctaatc gatgctcatt acaagtatca gtatgaagtc
     6541 tccaaaagag gaaaaatttc tgattacagc caggtagttc aatctaagga aaacaattcc
     6601 tttttatcct tgccaaaagc aggtaaaaaa ccactactca cactgttagc ctttcaagca
     6661 aataatatga aaaagtgcga tgtgatccag tgtgaattag tcaatgtaga aaaaatcaat
     6721 aaataaggga agtgagtcac attcaagaac ttgtagaaaa attgatcaat aaaatgagtg
     6781 ccatttttct gttactgttg gtatccattc tatatttaat atggacggtg gggttaaatc
     6841 ctcctacgat attatttatt tatgataatg ctgcacagtt agtgacgttt ttcgtaggct
     6901 gtttgtttct tttgaatctg tacaaggtaa agagaaacga tctattcttc attgcagcag
     6961 gcattctttt ttaccttttc ttttcttttt ttagaagcta ccgaggagat actttctatg
     7021 gtgatctgat cgttccgaca attattgcta ttattttgat tgtaaaatgg acgaaattta
     7081 ctgtaattga tcgtagcttg tatcttgtag tattctatgt ctttttactc gtaacggttt
     7141 atcgagtatt tactgagata ccagtaccag aaggacaaag tatttggaat ccatcgaaca
     7201 aattatcaga tatttggatc aatacaaata cgataggtag ttctttaatg acattagccc
     7261 ttcttatcac aggatttgct agttcatttg gaaaatggta catgcgattg ctatcattac
     7321 cagcgttgat tcttgctggg gcaacgattt gggtttgcca atcgaaagca gcattatatg
     7381 cgcttgttat cttcattatc ttagaaattt tacctaagaa ggtttttcga aatacacact
     7441 tgtccttttg gatgtatgca gcagtttcgg ttctagcttt accgatttct tattttgctg
     7501 caatgtcaga caaagttcac ttatttacag gacgagaaga aatttggcgc aaattctatg
     7561 aaacattagg cgaaaaaaca ggacaaatat ttgtagggat gaaacctttc tttttccata
     7621 gaggaaatca gattctaggt aatcataata cgtatcacgc actcgtcaat cactatggat
     7681 tgattggttt tgttctatcg attattcttt tgcttagttt cttatggttg ctcgtaagaa
     7741 aaagtgagct gacaaatgga caactaacat tcttgtgggc ttttttagcg atcatgtgtc
     7801 aatcgttcat ggaagaaaca ttaacgacaa tcagttgggt gccaattgta ttcttaatgt
     7861 tagcaatggc tacacaccaa tataaaacca ccagataaat gaaatagaat agtaataaga
     7921 gaaaacactt tttcgttgtg aaaaagtgtt ttttgttttg tctgaaagga ggcagatgga
     7981 tgaaaaaatg gttatttggt tttttaggag tcgctttaat cgtcgtttgc agtgtgtttg
     8041 gctatgttag ctaccaaaaa catgaaggag aggtgtttaa gcaaaatata gaaaaaaaga
     8101 tgcccgtaga tcaaatcaat gcacacgcaa agagttataa ggaggatgca acgaacgtca
     8161 ataatgatat gtctttgggg caaatgttgt ccatacaaaa agaagcaatc gaaatgggcg
     8221 tcaataaaca agtatttgca caaattcaga ttcctgcact tggtttagca ttgccaattt
     8281 ttaaaggggc aaatcaatac actttgagtc ttggagcggc tacttatttt tatgaagatg
     8341 ccgaaatggg taaaggaaac tatgtcctag caggtcataa catggaaatg ccaggtgttt
     8401 tattttctga tattcaaaag ttgtcattag gggaggtgat ggacttagtt agtaacgatg
     8461 gcgtctatcg ttacaaggta acgcgtaaat ttatcgtaca tgagtacttt aaattaatcg
     8521 atggcgttcc tgaagagaac tctttcttgt ctttaccaaa gaaaggagag aaacccttat
     8581 taacgttgtt tacttgtgtt tatacgtcac aaggaaaaga aagatacgtg gtacagggag
     8641 agctacaata acaagaattt aatcaacgcg agtcgttgaa atatgaaatg aggagagtaa
     8701 aaaatggcaa taaatcggta tgtaaaaaaa gctggaatga ttgttggaat gttaggaatc
     8761 attgcaggct gctttcaggg gtatcgagct tatgcagaag atgtcacgca aaaaacgcca
     8821 ccagaaaggg tcaatatcac ggttcataaa ttaatgtacg atcaaagtac gcaattgaac
     8881 gttgatattg acggaatcaa aaatgatggt tatacgcacg atcaatatcc tacaggtgta
     8941 acgaaataca acaaggcaga ttatggtgat gttgagttta cgttaggaaa tattacggat
     9001 caagtattac cgactgaaga ttctgatcta accaacgcga aagtggacga aatcgttaaa
     9061 gatgtagaag acaagggatc taacagtgag tacgtcaaga atgcaaccaa taaaattact
     9121 tcagctgtag atgaaaatgg tgagatcact tttgctgatc aaccagccta tgtcaattcc
     9181 aaagggaatg tatatgtggt ttatgaaagt aaatccgctg ctggattagt cacacaaaaa
     9241 gcaaaaccaa tggttgtgat tgcgccaatg actgataata caggttcagg ttttttaaaa
     9301 gacattcact tatatcctaa aaatattgtt tctaagttga gttttgaatt aacgaaattt
     9361 ggtgacgatg gcacagctca aagcaaacaa acacctttaa aaggggcaaa atttgagtta
     9421 tacaagggcg aacctggaaa aggaacaaaa ttaggagatc ttgtatcgga tgatcaagga
     9481 aagctgactg caactgattt gacgttagga aaatactact ttgtggaagt tccttcagaa
     9541 gttgtagttg gatcagatca agaaccaaca gcagaccaat atttgttagg cgcagacgct
     9601 cgcaacgatg cgcacaataa gttaaccttt gaaattacga atgacggcgt gacaagtgat
     9661 ttaaaagctt cctacgtgaa ctataaagca ccagtgatcg ataaaacagt gacaaatgga
     9721 acaggagaag aacattcttt ccaaattggt gacgcagtga attatcaagg tacaattcat
     9781 atccctacag atatcgcagg tggaacagat gggattacag taaatggtgt aaaaagtgaa
     9841 acttctcctt acagtgtatt taaatggggc gacacagcag gtaaaggact ttcttatgtt
     9901 gctgaaaaag cagatattaa agtaacaaat aatgatggtt cagtcgtatt aaaagaaaat
     9961 actgactata aaatcgaaaa ttctgatagt ggttttgtga tcgattttat cgtaaataat
    10021 ggacaagtaa gtgatacagt tgcgaattta catggtcaag atctaaaaat gacttataac
    10081 atgtttgtga atgatagtgc tgaaatcgca aatccattaa caaatagcgt ggatttcgtt
    10141 tatgacaata atccatttaa tcaggaagaa caccacgaaa aaacgaaagc tgacgttgtg
    10201 acttatggcg caaaattctt aaaagtcgat agcggcctat ttggaacagg tatcaaagca
    10261 acaccgcttg aaggcgcaga atttgcagct aagaatgcag aaggtaagta ctacggtgga
    10321 cttactgata cagataaaga tggtgtcaaa gaagcagttt gggtagacga tgtagcaaat
    10381 gcagcaatcc taaaatcaga taaagagggt cattttgaaa tcactggttt aactgaagga
    10441 gattactcac tggaagaaac aaaagctcct gaaaactatc aaaaattaac aaaagagatc
    10501 tctttcaaag tagacaaaga ttcatacaaa gaagaaaacc gaatcacgat caaaaataat
    10561 caaaaagctt ccgtaccaat gactggtagc aacggtttcc aatcttacgt attgatctct
    10621 tgcttgttgc ttggggcagg cgcaatttct gcagttgttt actttaagaa gaaagcctag
    10681 aaggatcagc taatgattat cagacaccct aagaaaaagc gaatcatggg taaatggatc
    10741 attgctttct ggttactttc agctgttggt gtcttacttt tgatgcctgc tgaagcgagc
    10801 gtggcgaaat accaacaaaa tcagcagatt gccgcaatcg atcgaacagg aacggcagca
    10861 gaaacggatt cttctttgga tgttgctaag attgagttag gcgatcctgt tggtattctt
    10921 acaattc
//
LOCUS       DAPBCF010000076        10497 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.078, whole genome shotgun sequence.
ACCESSION   DAPBCF010000076 DAPBCF010000000
VERSION     DAPBCF010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.078"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..361)
                     /locus_tag="RD508_002531"
     CDS             complement(<1..361)
                     /locus_tag="RD508_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HDT7737061.1"
                     /translation="MATVWMGLALVGNTFSPNSAMEGQGVIDVLTHIYTTGPAEYAKS
                     ILVNVFFGAFFGRVLVDSGIAATLIRKVVELGGDKPRITMSLLCIVTAVIFMSMTGIG
                     PVISIAVIVLPILMSLGI"
     gene            complement(713..1072)
                     /gene="rplT"
                     /locus_tag="RD508_002532"
     CDS             complement(713..1072)
                     /gene="rplT"
                     /locus_tag="RD508_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDT7737062.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(1125..1325)
                     /gene="rpmI"
                     /locus_tag="RD508_002533"
     CDS             complement(1125..1325)
                     /gene="rpmI"
                     /locus_tag="RD508_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDT7737063.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(1397..1921)
                     /gene="infC"
                     /locus_tag="RD508_002534"
     CDS             complement(1397..1921)
                     /gene="infC"
                     /locus_tag="RD508_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDT7737064.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(1965..2090)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            2241..2873
                     /locus_tag="RD508_002535"
     CDS             2241..2873
                     /locus_tag="RD508_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDT7737065.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(2875..3780)
                     /locus_tag="RD508_002536"
     CDS             complement(2875..3780)
                     /locus_tag="RD508_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDT7737066.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(3865..4524)
                     /locus_tag="RD508_002537"
     CDS             complement(3865..4524)
                     /locus_tag="RD508_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDT7737067.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     CVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            4840..5784
                     /gene="mvk"
                     /locus_tag="RD508_002538"
     CDS             4840..5784
                     /gene="mvk"
                     /locus_tag="RD508_002538"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HDT7737068.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            5777..6754
                     /gene="mvaD"
                     /locus_tag="RD508_002539"
     CDS             5777..6754
                     /gene="mvaD"
                     /locus_tag="RD508_002539"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HDT7737069.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            6767..7852
                     /locus_tag="RD508_002540"
     CDS             6767..7852
                     /locus_tag="RD508_002540"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HDT7737070.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            7849..8913
                     /locus_tag="RD508_002541"
     CDS             7849..8913
                     /locus_tag="RD508_002541"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HDT7737071.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(9162..9965)
                     /locus_tag="RD508_002542"
     CDS             complement(9162..9965)
                     /locus_tag="RD508_002542"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HDT7737072.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(9985..10290)
                     /gene="kduI"
                     /locus_tag="RD508_002543"
                     /pseudo
     CDS             complement(9985..10290)
                     /gene="kduI"
                     /locus_tag="RD508_002543"
                     /inference="COORDINATES: protein motif:HMM:NF002091.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
     gene            complement(10272..>10497)
                     /locus_tag="RD508_002544"
     CDS             complement(10272..>10497)
                     /locus_tag="RD508_002544"
                     /inference="COORDINATES: protein motif:HMM:NF018513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HDT7737073.1"
                     /translation="LWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKIIKEAIPSLLLI
                     VIIIGGILTGIFTAVEASAIAVIYKWVIRF"
BASE COUNT         3107 a         2220 c         2008 g         3162 t
ORIGIN      
        1 aaatacctaa tgacatcaag atcggcaaca caataactgc aatagaaatc actggtccga
       61 ttcctgtcat cgacatgaat ataacagcgg ttacaataca tagtaagctc atcgtgattc
      121 ttggcttgtc ccctccaagt tcaactacct ttcgaatcag ggtagctgcg attccgctat
      181 ctactagaac acgcccgaaa aaggcaccaa agaagacatt taccaagatc gatttggcgt
      241 actcagctgg ccccgtcgta tagatatgcg tcaacacatc aattactcct tgcccttcca
      301 tcgccgagtt tggtgaaaac gtgtttccga ctagcgctaa tcccatccat acagtagcca
      361 tgatgacaaa agccgaccat caagttgtag ccttttacac agtaccagac catgaaaaag
      421 aatgagataa ctaacaaaat accaataata atatcactca tgttattcct ccgtccattt
      481 tgtttttctg ataagcaaac taatatatca gtcaaactca ttctaactta tgtagttagc
      541 gctttcatta aaggatgacc ataaatgttc agttttcaat taaaaaacct taattatgtt
      601 attttagact tatacgttat tgtcctgttt catttgatgg aggattgtaa ataaaaaaag
      661 aggaaagaac ataacttttc gttatcttct ttcctcttta taattgttta gcttatttag
      721 ccaaagcttc ttttgcttgg tcagccaatg cagtaaatgc tgctgcatcg ttaacagcca
      781 agtcagctaa cattttacgg ttgatgtcga tttcagcaac tttcaaaccg tgcattaatt
      841 ttgagtagct caagccattc atacgagctg ctgcgttgat acgagcaatc cacaatttac
      901 ggaagtcgcg tttcttttga cgacgatcgc gatatgcgta gttgtatgaa ttcattactt
      961 gttcttttgc tgttttaaat aaagtgtgtt ttgaaccgta gtaacctttt gctaatttta
     1021 gcactctttt acgacgttta cgagttactg ttccaccttt aacacgtgcc atgtataatt
     1081 cctcctaata aaaataaatc ttcagattct gttatttgta cttcttattt catttttgct
     1141 agttgttggc gaatacgttt gaagtcgcca ctagaaacca tgcttgcttt acgcaattga
     1201 cggcgttgtt tttttgtttt gccgtggaaa cggtgacttg taaacgcgcg gaagcgtttc
     1261 aatccgcctt taccagtacg tttgaaacgt tttgctgatc cgcggtgtgt tttttgtttt
     1321 ggcatgacta tatttcctcc tcaaaatctt tcgttatccg actatcggct gtccaacagc
     1381 cagttagtca ttcaaattac ttactgtcgt ttttcggtgc cagcgtcaag aacatgctgc
     1441 gtccgtccat tttcgctttt tgttccactg ttgcaatatc cgcagtttct tcagctaagc
     1501 gattcaagac tttttgacca atttctttat gggtaatggc acggcctttg aaacggatag
     1561 aagctttcac tttatcgccc ttttccaaga acttacgtgc attacgaagt tttgtattga
     1621 agtcattcaa gtcgatcgta ggacttaagc gaacttcttt tacattgatc actttttgtt
     1681 ttttacgcgc ttcgcggtct ttcttttgtt gttcgaaacg gtatttaccg tagtccatga
     1741 ttcgcgcaac tggtggtttc gcaccagggg caactaacac aagatccaag tttgcttgtt
     1801 ctgcaatatt caatgcttct gcttttgtct taactcctaa ttgctcacca tctgaaccga
     1861 tcaatcgtaa ctctcgtgca cgaatgccgt cgttaaccat catatccttt gctatggtca
     1921 ttcacctcca aatattatga gagaaagaaa agcttaccga ataaacggca ataaaaaaac
     1981 gagttctctt acagaacccg cgcgtacttc acctaataga accagtgaaa actatctagc
     2041 ccagtgacat tatcaactaa ggcgagaagc gggtgcttct gcttttattt ctcaaccatt
     2101 atagtatagc aaaaactaat ctttttgtca atgtttttca tacagtttgt cttccttttc
     2161 tgaaaatgat tagattagca ggctttctag cagtgattcc cgcttctttg ctatactaaa
     2221 gaaaaacgag gtgaacccac atgaaaaaaa tcgaacctat tccaccttct cttcctcttc
     2281 ttacaaaggg agagttttat ttagaagatg aggagatctt ctctggtctt ctgatcaacg
     2341 gaggtaacca aagctatctc gatgccaaaa atatggtatt aagagagagt catatccaaa
     2401 aacttacgat gcaaaaaaca ggtttacgtc attttgaatg cagtaatgtc atttttgaaa
     2461 aatgtgattt ttccaatctg gagtggattg gtggcagttt ccaccaagtc gtgtttcatc
     2521 aatgtaaatt aacaggtacg aattttgccg aaagttatct tcgagactgt actttcactg
     2581 attgtattgc ttcgatggct tcctttagta gtacaaactt gaaagctgtc tccttcgatc
     2641 attgtcaatt agaagacagc gaattttatg aggtcacttg gaaaaacctt tttttgtctg
     2701 acaatcagtt aaccggttcg aactggtttc gaacttctct gaagggatta gactttacga
     2761 ctaatttctt cacaacaatc gctttatctc aagattcttt ggcgggacta atcgtcaatc
     2821 aagagcaagc acttgtgatc gcccaagccc ttggtttgca gatcaaagac tagatcaacg
     2881 aatccgccgc cacagtgcaa taagcatcca aatagataag accaaactga tgatcaaggc
     2941 gatttcccat ccgaaaacgg aatgggtaaa gggtaactgg agattcattc cgaagaatcc
     3001 tgtcacaata gttggaacgg tcaagatcag cgaccagacc gtcaaaaatt tcatcgtgtc
     3061 attcaagttg ttattcagca aattattata agtgccagag agctggtcta aaatctgcga
     3121 agctaagttc gtcatttcaa ctgcttgtcg tgcttcgatc agtgcatcgt ccaactcttc
     3181 tttttccttt tctgacaact tgcgataaat agccagtgcc ttgatttgtt ctaaaagtac
     3241 tacattttgt tttgttcctg taactaagta aaccaaaccg atctctaaat ctgaaagttg
     3301 cagcagattc ttgttcgttg ttttttctct taatttcaga ttaagccgct gacgttcact
     3361 attcacttcc tcgattaaag gaaaaaagga atcagaaatc aaaaacaatg tacgaaacaa
     3421 taaactgtat acactcatgt ctggcatccg ttccaaaagc gatcgaatta gtcgaatcac
     3481 gtactcggta ttcggcgtgg taaatgtaaa caaaccgtct tcttttaaaa taaaagcgat
     3541 aggactagtt tcataatgat tatcgacttt ttgctggtgc ggaacatttg atacaagcag
     3601 taacgcttca tcaaaagaat cgtactctac gcgcgcccgt tcatttttat ctagagaata
     3661 agtcagcatc tcgtcactaa tgccatattc ttcttttaag tttttaacag ctagcacatc
     3721 gttttgctgt acattgatcc aaaaattacg gtcttgatta aaatagtgtt tttcccgcat
     3781 actctatcct cctgacattt gtttccagta taaagaaaaa agtcgctcaa ataaaggttt
     3841 accctttatt tgagcaactg taaatcaaat ggatactttg gtttggcgaa tctctgctaa
     3901 tttttcttcg atcattttca agacttcttc ttttgcttga ggatcttcca caaaattata
     3961 gcggtctcca tcgatttgga tttttggact ttctttgtat tcttcatacc attgatcata
     4021 acgtctgttc aattctttgt aataatcgta tagacttggg tcaaaggaca attgttcata
     4081 cgaacgacca cgtttttcga tacgctctaa catcgtatca aaagatacac gaatatgaac
     4141 taataaatcc ggatgttttt tatgggcagc atagggaagt tcttccatca tgttttccag
     4201 cagttcatca tacacacaaa cttctgtttc tgttgctctt cctagatctg catttagatg
     4261 gaaaagcagt gaatcttcat aaatcgaacg gtccaataca ttattgtcat ctttcattgc
     4321 ttgtttgatg cttgcaaaac gtttattcaa aaaataaatt tgcagcaaaa aagcatactg
     4381 ttcagggttt gcataaaata agggcaagac ttcattatca tcaatcgatt cataaaatgc
     4441 ctgactatca aagtgttcag ccatcatttc tgttaaactt gattttccgg caccaattgt
     4501 acctgctaaa acgatcacgc tcatttacct ccagctcact tcatcactaa atattgtgtt
     4561 taactccaac cttttttaaa tataccccca atatctagta gtgtcaattg tattttttct
     4621 agtcaaagaa gaaaaaaagt caaaaaattc ttaagaaaaa agtgtttttt ctttagaaaa
     4681 cgtattctta gttttacttc tgagatggtt ttagtaaaat aaaggaggaa tgttttttga
     4741 gacccttagt ggacaaaaaa attcgtgaag cagcgcaact cgttttgggc gctttatttt
     4801 ttgcttaaaa atcactttta cgtgagaagg agttagatta tggcaaacta tggccaagga
     4861 gaatcaagcg gaaagatcat attgatgggc gagcacgcgg ttgtttatgg agaaccagcg
     4921 attgcctttc ctttctatgc aacaaaagtc accgcattcc ttgaagagct ggatgcaatg
     4981 gacgatcaac tggtttcttc ctactattca ggaaatttag ccgaagctcc tcatgcatta
     5041 aaaaatatca aaaaattatt cattcactta aaaaaacagc atgacatcca aaaaaacttg
     5101 caactgacca ttgaaagcac gattcctgct gaacgtggaa tgggatcaag cgctgcagtc
     5161 gccacagcag tcactcgtgc tttttatgat tacttagcat ttcctttgtc tcgtgaaata
     5221 ctattagaaa atgtccagct ttcggaaaaa atcgcccacg gtaatcctag tggaatcgat
     5281 gcagccgcta ctagcagctt gcagccgatt tattttacaa aagggcatcc ttttgactac
     5341 ttttctttga acatcgatgc ttttttgatt gtcgctgata caggaatcaa aggacaaaca
     5401 agagaagccg tcaaagatgt cgctcacctc tttgaaaccc agcctcatga aactggacaa
     5461 atgatccaaa aattaggata cttgacgaag caagcaaaac aagcaatcat tgagaattca
     5521 ccagaaacgt tggcacagac aatggatgaa tcacagtcac ttctggaaaa gctgacaatc
     5581 agcaatgatt ttcttaatct attgatccaa acagcaaaag ataccggggc attgggtgcc
     5641 aaattaactg gcggtggacg cggtggctgt atgattgcat tagcacaaac aaaaacaaaa
     5701 gcccaagaaa tcagtcaagc acttgaagat gcgggtgctg ctgaaacttg gatacaagga
     5761 ttaggagtac atacctatgt ttaaaggcaa agcacgcgca tataccaaca ttgctctaat
     5821 caaatattgg ggtaagaaaa atgaagaact catccttcca atgaacaaca gcctttcgtt
     5881 aacattggat gcattttata cagagacaga agtcatcttt tctgatagct atatggtaga
     5941 tgaattttat ctagatggca ccttacaaga cgaaaaagca acaaaaaaag tcagtcagtt
     6001 tcttgacctt tttcgtaaag aagccggcct ctcactaaaa gcttcagtaa tcagtcagaa
     6061 tttcgttcct accgcagctg gattagcctc ctctgccagc gggctagctg ctttagcagg
     6121 agcttgcaat actgctctta agcttggatt agacgatctc tctctttcaa gatttgctcg
     6181 acgcgggtct ggttcagctt gccgaagtat tttcggtggt ttcgttgaat gggaaaaagg
     6241 ccatgacgac ttaagttctt acgctaagcc agtcccttcc gattctttcg aagacgattt
     6301 agcaatggtt ttcgttttga tcaacgacca gaaaaaagaa gtgtccagca gaaatgggat
     6361 gcgtcgaaca gtcgaaacat ccagttttta tcaaggctgg ttagattccg ttgaagggga
     6421 tctatatcaa ttgaaacaag caatcaaaac aaaagatttc caacttctcg gagaaacgat
     6481 ggaaagaaac ggactaaaaa tgcatggaac gactttagct gcccagcctc cattcactta
     6541 ctggtctcct gacagcttaa aagcgatgga tgcggtgcgg caattgagaa aaaaaggcat
     6601 tccatgctac tttacgatgg atgctggccc taatgtcaaa gttttagtgg aaaacagcca
     6661 tttatctgag gtacaagaaa catttaccaa attatttagc aaagaacaag taattactgc
     6721 ccatgctggt ccaggaattg cgattattga ataaagggag atttttatga ttgaagtatc
     6781 tgcaccaggc aaactctata ttgccggaga atatgcagtt gttgaaacag gacatccagc
     6841 agttatcgct gcagtcgatc aattcgtaac agtcactgta gaatccgcac gaaaagtcgg
     6901 aagtatccaa tctgcacaat atagtgggat gcctgtacgt tggacaagac gcaacggaga
     6961 attagtttta gatattcggg aaaatccttt tcattatatc cttgctgcta ttcgtttgac
     7021 tgaaaagtat gcacaagaaa aaaacattct tttatccttt tatgatctga aagtaacaag
     7081 tgagttagac agttcaaatg gccggaaata tggattgggt tctagcggtg ccgtgaccgt
     7141 tgcaacggtc aaagccttga atgtttttta cgcgttgaat ttatctcaat tggagatttt
     7201 caagattgca gcactagcca atttagcagt tcaagataat ggttcctgcg gcgacatcgc
     7261 tgctagctgt tatggtggct ggatcgcttt ctcaaccttc gaccatcctt ggctccaaga
     7321 acaagaaact cagcattcta tcagtgagtt acttgccctg gattggccag gtctatccat
     7381 tgagccattg attgctcctg aagatttacg tttattgatt ggttggacgg gtagccctgc
     7441 ctctacttct gatttggtcg atcaagttca ccgttcgaga gaagacaaaa tggtggctta
     7501 tcagcttttc ttaaaaaaca gtacagaatg tgtcaacgaa atgatcaaag ggtttaaaga
     7561 aaataatgta acgttgatcc aacagatgat tcgaaaaaac cgacaattac tgcatgattt
     7621 atctgcaatc actggggtcg tcatcgaaac gcctgctttg aacaaattgt gtaatttagc
     7681 tgaacagtat gaaggagccg caaaatcttc tggtgcaggt ggtggcgatt gcggaatcgt
     7741 aattgttgac cagaaatctg gcatccttcc tttaatgagt gcatgggaaa aagcagaaat
     7801 cactccactg ccgttacatg tctatagcga tcaaagaaag gaaaaccgat gaatcgaaaa
     7861 gacgaacatg tttcactagc taaagccttt catgataaac aaaaaaacga atttgacttc
     7921 gtacggatca tccataaccc tttgccgcaa atagcagttt ctgatgtcga tctaagtaca
     7981 caggcagttg ggtttacact aagcagccca ttttatatca atgcgatgac tggcggaagc
     8041 gaaaaaacaa aaaaaatcaa ccaagatctt gcaatcgtcg caagagaagc agatttgatg
     8101 attgccactg gttcagtcag cgctgccttg aaagaccctt ctttagccga tacttatacg
     8161 attatgcgac aagaatatcc tcacgggaaa atcattgcca acatcggtgc agggacttct
     8221 gtcgaaagag cccaagaagc tatccgattg tttcacgcag atgccttaca gattcatttg
     8281 aatgcacctc aagagttggt tatgcctgag ggagaccgtg attttaccaa ttggaaagta
     8341 cttattcaag agactcaaac agccattgac gtccccctca tcgtaaaaga agtcggtttt
     8401 ggcatgacaa gagaaacgct caatgatcta gctgctttag gagttcatac agttgatatc
     8461 agcggtcgaa gcggaacaag cttcacccag atcgaaaacg cccgtcgctc caagcgggaa
     8521 ctgagttatt tagctgactg ggggcaatcg acagtctctt cattgcttga agcaaatgaa
     8581 gcagacactt ctatggaaat cctagcctcc ggaggtatcc gcaatgccta tgacatattt
     8641 aaagcccttt gtctcggcgc aaatgcagtg ggtacttcag gaaccgtact gacgcatctg
     8701 atgaatcacg gcgtagaaga aactattata ctgatgaagc aatggcaaga agagcttcgt
     8761 ctgctttata ctatggtcgg cgcaacgaat accgcggccc tacaccaaca atcactgatc
     8821 ttttccggac cagtgaagga ttggtgcgaa gcaagaggga tcgacttagt gaagtatgga
     8881 agacgcacag aaaagagcgt gggacaaaag taaagaacac ttttatccca cgctctaaac
     8941 acgtataaac ggcggaagca aaagcaactc cttcggaaat aagctgaaat tcacaaaaat
     9001 ttgaaaagca attttcgtga attccttctt atttcttgga gttaaacgct tctgtcccag
     9061 cctctttttt cgaataaatg atgtttaatc agctgtcctt cggtattcgt tcaagccgct
     9121 gatttcacaa cctctccact aaacggtgta ctaaagctct tttaaggttg ttttccgata
     9181 taggcaagta tgcctccgtc cacatacaag acatggccgt taacgaaatc agatgcgcta
     9241 gaagccaaga agacagatgg tccagccaaa tcgattggct cgccccagcg tgctgctggc
     9301 gtacgtccaa cgataaattg atcgaatgga tgacgttcac cgttttcttg tgtttcgcgt
     9361 aatggagcag tttgcggtgt agcaatataa cctggtccaa ttccattaca ttggatattg
     9421 tattgaccgt attcagaagc gatgtttttc gtcagcattt ttaatccgcc ttttgccgca
     9481 gcataagcac tgaccgtttc gcgtcctaat tcactcatca tggagcagat attgatgatt
     9541 ttaccgccgc ctttttcgat catatcccga ataactgctt ttgaaacgat gaatggggca
     9601 tttaaatcca cgtcgattac ttggcggaag tctgccgcat ccatttcgat catcggtgtc
     9661 cgtttgatga tccctgcatt gttgactaga atatcaactg aacctacatc ttctttgatc
     9721 tgttgaacca tcgcttgaac cgcttcttca tcggtcacat cgcagacata accttttgca
     9781 tcgatgcctg cttctttata atgcgctata ccttcatcaa ctgattcttg attcaagtta
     9841 ttaaatacga tttttgctcc tgctgtagct aaagagcgtg caatctcaaa tccaatacca
     9901 tagacagcac cggtgactaa tgctactttt ccatctaaac gaaacatatc catactaaat
     9961 tccatcattt tctctccctt atgcttattt taattgatcc atttgcacca tatccatgtc
    10021 tgtataggtg atattttctc cgcacattgc ccagatgaat gagtaattgc ttgtacctac
    10081 acctgaatgg atcgaccagc ttggcgaaat aatggcttgt tcattgtcta cgactaaatg
    10141 ttttgtttca tctggtttgc ccatcatatg gaacacacgt gtatcttcat tggcataatc
    10201 aaaatagaca taagcttcca tacgacgttc atgtgtatga caaggcatcg tattccaagc
    10261 acttcctggt tctaaaatcg tataacccat ttataaatga cagctatcgc tgaagcttct
    10321 actgctgtaa atatccccgt caagatacca ccgataatga tgacaatcaa tagaaggcta
    10381 ggaatcgcct cttttattat ttttccagca tgagccatct gtcctttttc gacaacaggg
    10441 tatttattct ttttagcaac gatgaatgct actagcatga ttcctagcgc ccacaaa
//
LOCUS       DAPBCF010000077        10380 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.079, whole genome shotgun sequence.
ACCESSION   DAPBCF010000077 DAPBCF010000000
VERSION     DAPBCF010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.079"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(49..1515)
                     /locus_tag="RD508_002545"
     CDS             complement(49..1515)
                     /locus_tag="RD508_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDT7737074.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1902..2498
                     /locus_tag="RD508_002546"
     CDS             1902..2498
                     /locus_tag="RD508_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDT7737075.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2556..3038)
                     /locus_tag="RD508_002547"
     CDS             complement(2556..3038)
                     /locus_tag="RD508_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737076.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3144..3341)
                     /locus_tag="RD508_002548"
     CDS             complement(3144..3341)
                     /locus_tag="RD508_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737077.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3636..4394
                     /locus_tag="RD508_002549"
     CDS             3636..4394
                     /locus_tag="RD508_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HDT7737078.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4454..4882
                     /locus_tag="RD508_002550"
     CDS             4454..4882
                     /locus_tag="RD508_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737079.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4928..5000
                     /locus_tag="RD508_002551"
     tRNA            4928..5000
                     /locus_tag="RD508_002551"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4961..4963,aa:Gln,seq:ctg)
     gene            complement(5150..5521)
                     /locus_tag="RD508_002552"
     CDS             complement(5150..5521)
                     /locus_tag="RD508_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7737080.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5736..5921
                     /locus_tag="RD508_002553"
     CDS             5736..5921
                     /locus_tag="RD508_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737081.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6004..6192)
                     /locus_tag="RD508_002554"
     CDS             complement(6004..6192)
                     /locus_tag="RD508_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737082.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6216..6479)
                     /locus_tag="RD508_002555"
     CDS             complement(6216..6479)
                     /locus_tag="RD508_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737083.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6637..6894
                     /locus_tag="RD508_002556"
     CDS             6637..6894
                     /locus_tag="RD508_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HDT7737084.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6965..7156)
                     /locus_tag="RD508_002557"
     CDS             complement(6965..7156)
                     /locus_tag="RD508_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737085.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7297..7617)
                     /locus_tag="RD508_002558"
     CDS             complement(7297..7617)
                     /locus_tag="RD508_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737086.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7640..8074)
                     /locus_tag="RD508_002559"
     CDS             complement(7640..8074)
                     /locus_tag="RD508_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7737087.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8409..9047
                     /locus_tag="RD508_002560"
     CDS             8409..9047
                     /locus_tag="RD508_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7737088.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(9371..9454)
                     /locus_tag="RD508_002561"
     tRNA            complement(9371..9454)
                     /locus_tag="RD508_002561"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9418..9420),aa:Leu,seq:cag)
     gene            9982..>10380
                     /locus_tag="RD508_002562"
     CDS             9982..>10380
                     /locus_tag="RD508_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7737089.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSV"
BASE COUNT         3279 a         2043 c         1663 g         3395 t
ORIGIN      
        1 aaacaggaac tgctgcaaat aagcaattcc tgtttttatg ttcattgatt aatgaataga
       61 gcccattagt tttttgattg gttctttcac agtaaatagc aagataccac cgacgattgc
      121 tactgcaccg ataataccga agtaagcaga ttctgttccc ggtgtgtaga agcgtgcaat
      181 ttgtgcattg attgcttgtg aagaagcatc agctaagaac caaatagcga ttgtttgtga
      241 ttcaaatgct cgtggtgcta attttgttgt cacagacaaa ccaactggtg aaagacacaa
      301 ttcagcaata accacgatga agaaacttcc caacaaccac aatggactta cttttccact
      361 tgtaccataa agcatacccg gcaacatcaa tagcaagtac gataatcctg caaataaaag
      421 tccaagagag aatttcacta ctgtagatgg ttgacgttca ccaagtttcg tccacatcgt
      481 tacgaatact ggtgtcagaa taaagatgaa aattggattc aatgattgat accagcttgc
      541 ttggatcgtt acaccaaata gcgtagattg tgtacgttca ctagcaaata aagctaagat
      601 agatgaacct tgttcttgta atgaccagaa aatgattgct gcaaggaata atgggatata
      661 agcccatact cttggttttt cttcagcagt tacatctttt gaagtcagca ttttgataaa
      721 gtaatacaac ggtaagataa tccccaatac actgattgta ttgacaaaaa agtcaattgt
      781 cagatgacca gttagttgtg ccccgccgaa tactgcagcg ataacaacaa gtgcgatgat
      841 caagttacgg atgaatcctt tacgttcttc agttgtcaaa ggattcggcg gtgttgtacc
      901 cactccgtct aatgtcttgc gtccttggat gatgtattgt aataatccaa agaacatccc
      961 aatagcagct aaagagaacc ctaaatgata gttatattct tgaccgattg taccaacgat
     1021 tagtggtgct aataatgccc ctaagttgac acccatgtaa aaaatcgaaa atcctgcatc
     1081 tcttcgcaag tcagtctttg aataaagatg tccgaccatg ccagaaacat ttggtttcaa
     1141 aaaggcggtt ccgataataa tcaatgccat cgaaacaaac aatgtactta caccaaatgg
     1201 taaagccaag acgatgtggc caagcataat gaaaactcca ccgaagaata cagtgcgttt
     1261 tgctcctaac actcggtcag atacccatcc gccgacgata ctagacatgt agatcaaaga
     1321 tccgtagatc gacatgatag ctaatgctgt tgctcgtggt aatccaagtc ccccgttggc
     1381 aactgtatcg tacatataat agataagtaa tgcacgcata ccgtaataac taaatcgttc
     1441 ccacatctca gtgaagaaca aagttgacaa tcccttcggc tgcccgaaga agcccttgtc
     1501 ttgctgtttt tccataatct ataccccaat tctttaaatt ttcagaaaat attatacatc
     1561 tttaccgaaa aatttaacta aaaaacttat ttaagaaata taaactaatt ttctataaaa
     1621 gcaagtaatt tttaatggca atatcataaa aaaaagaaga tagagattta ataattatat
     1681 atcagctgtt tttttcaaat aagcaaaaat tcctaaaaca caacaatgaa agcgataact
     1741 aagaaaatcc ttacataacg atttttctta ttaaaattgt tttttgaact tcgcttattt
     1801 tttgtgagca tatctgttta cttacttttt gtaaggtgct atacttcatt tcgtaatcaa
     1861 ttaaaaaaat gcaaaacgca aatcaaagga gaaattttat tatgacaact tttactgaca
     1921 ctttgaaaaa ccgccgttca atctatcatc taggacgtaa tgtttcactt tctaatgaag
     1981 aattaacaac tttgatcaaa gaagcaatta aagaaagccc aactgctttc aatgctcaat
     2041 caacacgcgc agttatcctt ttcggagatg cacatgaaaa actttgggaa atcactgaag
     2101 aagcacttcg cccattgact ccagcagaag ctttcccaaa tacacaaaac aaattagctg
     2161 gtttcaaaaa tggttatggt acagtattat tcttcaaaga tactgacgtg gtaaaaggtc
     2221 tacaagaaca atttgaatta tatgcagaca acttcccaga ttggtcagaa caatcaaacg
     2281 gaatcgcaac agctaatact tgggtagcat tagttgataa aggattgggc gcaaacttgc
     2341 aacattacaa cccagttatt gacgaagcag ttgcaaaaga atggaatatc ccttcaaact
     2401 ggaaactacg ttcgcaatta gtattcggtt caccagaaac accggctggg gaaaaagaat
     2461 acatgaacga tgccgatcgc ttccgcgtat ttggataatt ttatttgaaa taaaaaacag
     2521 aggttgtgac aaacatcttg tcgcaacctc tgtttttatt ctggatcaat cataatatca
     2581 atctctgcct catcgtttaa gcgttgggac aaaaatggaa ctaattcttc taatgatgca
     2641 gaaaatttca gcatcggtcc tcgccatccg tttcggaaaa aattcatttt tacgatttta
     2701 gaaccttttg gctgatataa tacaatttta ttgatctcag aaaaaggaac accttttttg
     2761 tcaaagctat tcaaaacaag tccttcttct gtgattcctc tactgtccaa caaaaaacta
     2821 ataaaaatca ttgctgacaa gatccctttt gccaattcat ctgctgtagg atgactgatg
     2881 agtgtatacc aaatgactag tgacactaag aagggtatca ccaagtagac ccatcgattt
     2941 cgcacagtcc gataaataat ttcttttcga accagccaaa gaaataaaaa catcacaaca
     3001 acgaataaaa acaatagaac cgtaaagaat gttaccatga caactcgcct cgctttttct
     3061 tctccagaaa ataggaaaag aatactgatt taccttctca aagaaattgg acttgcagca
     3121 cgccgcacgt ccaattgttt tctttattca aatgtatcat attttgcaac aaccatgctt
     3181 gctttttcat ctaataattc ttggtcctct gcagcacatt gggcaacttt gaccacggcg
     3241 cagtttgtca tttttgatac aacttcacca atgaccgttt ttgtaaaacc aattggtttg
     3301 catgcatatt gttctcctaa attaatcatt tcttccgtca tcaaaatcct cctaaactgc
     3361 tggaactttt ctccacatta ccactgctat ttctttggag atttaactca ttgattttta
     3421 tttacagtta aaaatcaacc ttacaggcat tatagcgtac tgttttcgtt ttcacaatta
     3481 aaacagctgt tgtatttaga agaatttttt tcaaaaaatt aaaacatatt ccttaaaaac
     3541 taattatttc ctacatatta aaatataata cttccatttc caataaaaat acatttataa
     3601 taggaaagat aaacagctga aaagggagat ttcaaatgaa gaaaaaaacg ttcaaaaaac
     3661 tattgtttct agggggcaca gctgctcttt tattaagcgg tacaagttat tacctacata
     3721 tccattctcc agaacataca atgaacactg cacaaaaaag ttcaacacaa aaaacgaaaa
     3781 agacaaaaga gaaagcagaa gttttactag atgttccatt agagagccag tttgattctc
     3841 cttctttaga aaatggctgt gaagtcactt cgctttctat gcttttatct ttttatggtt
     3901 atgaaacaac taaaaaccag ttagctgagc aattggatta cgtccctgtt ttcaatgcag
     3961 atgggactca tggcgatcct aatgaaggat ttgttggtga tatcagtggc ggagactggg
     4021 ctatggtcgt ctatgttccc ccagttgcct cccttgctca gcaaatcgtc caaacggatt
     4081 atcacacttt tccaaaaacc gatgctcaac tcgatgatat caaaaaagca ctatctaaag
     4141 gaaatcctgt ctggacttct gtgactatca attttgaagt cccagatgaa actgatttta
     4201 tgacttggac cacaaataat ggagaagtaa gagtcactcc tcttgttcat gcttgtgtag
     4261 tcactggata tgacaaagaa aatatttatg tcaacgatcc ctatggtgta aaaaatcgag
     4321 cagtaccgat caacgatttt tcggcgattt tcactgcaat gggtggacag atgctaactt
     4381 tggagaaaag ctagtaattc aaacaaaaat cccttatact caagatacca aacctttgaa
     4441 gggagcgtag ataatggaaa aattcacaca taaaaaaatg gatccaaatg aaattccgat
     4501 tatttttgtc cgtgactgca agggaaatgt tcaaggtaaa gtctctatta atgagtggaa
     4561 cgagcgtcgc agacctgcta ccctcaatga actggaaatc aaattgtatc gtcaatctct
     4621 tgtttattac gcagatcaag agtacgagaa agccaccgat ttattgaaat ttctaattgc
     4681 tcgaacagag tatactcgct ttgaatatat tgaacgttta gcaaacatct atcatattat
     4741 gaatgaacct gtcaaagaat atcagttatt ggacaccgtc ttgtcagtag cagaactgat
     4801 tgcccttcct gctggattag aaaagaaact agtacgccgc cttttacgag taaagcaaca
     4861 actatccgat caagaaaaat aacttgcgtt tttttaggaa agtgctatga ttattttgtt
     4921 gaataaatgg gatgtagcca aactggtaag gcacttgact ctgaatcaag caattgtagg
     4981 ttcgaaccct gccatcccaa tttgatgtgc ttgctgaaaa aatgaacccc ctgtaaaaga
     5041 acaatctttt tgcaggggga ttattgtatt atttttacta cttgtattta gtttacataa
     5101 ttaaattatg aataataaaa tcgggcgtat tcttaataca aaaactgatt tacccaataa
     5161 ttgctaatgc tttctccgga actttttctc taggaacttc ctcatacgtt tctatgtgtg
     5221 ctcctttatt gctaattttc aaataatgat tttcttttaa cacagaaaga ccattaaatt
     5281 caaccgttcg ttctttccca ttggcatcag cagctttctg cacatacctt gctgtaccat
     5341 attcatttac ttcctctggt ttttgtgtct ttacatagac ctctcctttt tcaactaatg
     5401 gatttagctg atcaagtata ccagggattt ctccataact tccttcagta taatatttca
     5461 gtccaaatag caaaatacca ctaatcgccg ccagtccaat caaatattta atcactttca
     5521 tctttctacc tccttgttat atattcagta tatgggtcag ttaaagaaat tccatccgtc
     5581 ccaagttgga gatttttctc ctactttaga agcgagaatc gagtgttttt ttagtaaaaa
     5641 tgatcgttat ttgatattat tgacgtgtgg ataaatcagt ttttctcgtt ttgtccatgt
     5701 aaaaaatcat gttgatagca aaggatgtgt tcaaaatgaa tcaagaagaa ttatttcaaa
     5761 aagtcaagga aatgattaag aacggcaatt tcgatggcgc aaaacgattt atcgaagaac
     5821 ataaagaaca attaggacct tataaagaga aagcccaaaa tcttttaaaa gatgtaaata
     5881 tcgacagtgt caaaaacaaa tttaaaaatc tattcaaata agtaaaactt tcacttttgt
     5941 aaaatcaaag gaggacaatg ctgctgcatc gtcctccttt ggttcttttc tgaatacttc
     6001 atactaaaat aaacgtgtcg gatcgtaatg ataagtcaca ttgccgttca gtgaggcttt
     6061 tcccaccaca tatttacgat tctccaactt cagccacgct tctcgaaaag ccattaattc
     6121 ttctcttttt acatcaatct tttcgatttt tccatcgatc aaatcttgaa taagttgttc
     6181 atatggattc atttttttcc tccatctgct gtcaatcaat aagttgtaaa aataggttca
     6241 tatgcttttt tggtatctag atcttctctg actttgactg tcgtataaat aattttttct
     6301 actgggatac tataataact tccttcacca ttattgaatc ggtgaacgtc tttctttgct
     6361 aaaataccat ttattttatt cgtcagtaca cgttgttcga cactgttact tacaacatag
     6421 taaatcaccc gaatattatt gatcaaatgc aaatcgattt ctaacactac atgatccatg
     6481 aaaatcccac tccttctttc actttgatta tagcaagttt ctcctctaat ttcaaaatcg
     6541 atacagattt taccggataa atccacaaaa ctgcttgcgc catttcgcac aaagtgttat
     6601 tttgtatcat ggactttatt tatcggaggc aatagtatga tcgcgatcgg tcaatttgtt
     6661 ttttatattc ctttttttat tatgataagc attcttttct attacataaa atggacaaaa
     6721 aagaagtttt cagttttact ggcctcttta cctgctgtat attttactta tcaaattttt
     6781 tcttttaggc attgggaaac aacgtctgta ttaataacac acatcatcga attgacgctt
     6841 tcagtaattt ttcttattat ttggatctat tttttatata agaatcagaa ttgaatccct
     6901 cgcatgttta aaaagaaaac gattaaagat gcagcaaatt tctgccgatc tttaatcgtt
     6961 ttttctattc tgttatacca aaaaaatgtt tgaatcggtg aaggatcgtt ccttgtttta
     7021 attctataaa ttcttgtgcg atcgggtact tttcttccaa attttctttg ttcttttcga
     7081 tcaggctttt cgcttcttca tattttttat ctgcacatag tgcttttact tcctgtaata
     7141 cttttcctgc ttccatttgc ctcaccctct tgccatttta ttgctttaag ttttatttaa
     7201 gttatacgca ttattctagt ttcatcccaa ataacctttt ttcattttta ctcctcgaac
     7261 taatcagttt tctaaaggct gattggttcg tcttttttat ttttcctcca tttcattctg
     7321 ctcttctgtt aatttatcta atgctttgat tgatgctgcg gctcttgcat aatcatagct
     7381 gtataattcc ataaatttat caggcagaac aaaccacgct ggatgataac cgttagctgt
     7441 gacagggaat cctttatctt gttggttatc tccatcccat ctcagagcaa cacctttttt
     7501 tcctttccac tttactaaag cgatcgagta tcccttcttt gtttgtgtgc cgtcttcaat
     7561 aattgctaaa atttctattt tttcttttgg cgcacggact tcttgaggac gaaccatttt
     7621 ctattcctcc cttatctcat tacttcacga ccaacacact gcaaggggca tgtgatacga
     7681 cataagaagc ggtcgatcca actaatgctt gttgtatagc accttttcct gtcgctccca
     7741 taacgatcaa atcaatattt tcttgtccag ggatgacatt ggcaatcaaa tttcttggat
     7801 ctccagtttc aactattgcg tggatctcag caatgccgta ctctttggca tcattgattt
     7861 ttttcagcat ggctacttct gttctttgtt tttcatctgc atagattttt gaaaaggcat
     7921 aggcactatg ggtcagctca actttgttga tgattgacac gataaataag tgggcttcat
     7981 tgtcctttgc taagtcaagg gcttcagcga acgctttgat cgattgtctt gatccgtcaa
     8041 ctgctaccat gatgttctgg tatcttttac tcattggaac cgcctccttt ttcttttatt
     8101 gtaacatctc aagcaaaaat acaaaaaata tacgcaatat gtaaataaaa tgatgaacaa
     8161 aagcaatttc tttcaagtta tttatacatt tcttttctca tcagaacacc tgttctaatc
     8221 ccattatttc tgcattatgt gaaattcctc atcatttttc acatcgagcg aacatcattc
     8281 tgttacaaaa aacgtggatt tgtcataaat tgtcatgctt cttttaccta tgaaatattt
     8341 tcacgtgtta aagtattcct cgttgaacac aacaaataaa actttttaac gaataaagga
     8401 gatttttcat gacatcactt aaaactttac tttttggaac aactttggct gccggcgctg
     8461 cattcttcat gggaacgact gctcatgcgg acgaagctta taccgttcaa tcaggtgata
     8521 ctctatcaac gatttctcaa aaatacgttg gtgataactc cttgatcaat gccattgcag
     8581 aatcaaattc aatttctgat attaacctga tctactcagg acaacaatta acaatcccaa
     8641 cagaaggctc tgcacaagca gctgctgaac ctcaagcagc cgttcaagaa gcaccagtcc
     8701 aagctgaacc tgttcaagct gaacaacctg ttgtacaaga aacggttcaa acggaaacac
     8761 aagcagcgcc tgttgctgaa acacaacctg ctcctgctgt aacagaaact gctgctactc
     8821 cagcaagtac aagctctgca aaagaatgga tcgcacaaaa agaatcaagc ggttcttaca
     8881 cagcaacgaa cggacgttac atcggccgtt accaattaga ttcttcttac ttaaatggtg
     8941 actactctgc tgcaaaccaa gaaagagtag cagaacaata tgttacttca cgttatggtt
     9001 cttgggaagc ggcgaaagca ttctgggaag caaacggttg gtactaagat tcattatttg
     9061 aacgtttaaa cacattcaaa atatagtaag aggtcatgcg atttattctt tcgcatgacc
     9121 tctttttgag tttaagttta gtctttattc cttaactatc gtttgccagt atttcttgta
     9181 tcagaatcta taaatctact atttgaatca atctattagg ttttaaactg tcccaccttc
     9241 acacaaattt tttttgattt atttgaatct ggttccgttg tttaaaattt ttcctatatt
     9301 cttttagata atatgttatt ttctttctca tcgctccagg tgtaccttct ctttataaaa
     9361 aaacaaatta tgcggctaag aagactcgaa cttccacgag gtcaccctca ctagcgcctg
     9421 aagctagcgc gtctgccaat tccgccatag ccgcatcaca tcttttagtt taggattaca
     9481 tgtgtttttt gtcaagaaca tatttttgtt ctttttcatt tctgtacgcc ctcccttatg
     9541 ccatctacac aaataattca tccgagcaac tccatcatct attgagggtt ggtgaaaaaa
     9601 tctgttttat ccatatgatc gatttcaatg ttaaacgaac gactctggga ttagtaacta
     9661 ttttattttt ttcttcattt cttttttcct ctttttctcg attcagctat cttctttcat
     9721 ttggatattg attatttctt ctgttgatta ctatccttct ggaattctag acgctgaagt
     9781 aattcacgtt ttctttcttc tagagatcat aagtaacgaa tgaacgaact tcaaataatt
     9841 tttttattgt aattcatatt tgtattgttc gatgattctt aatacgatat gacacaataa
     9901 ataaaaatag gcatggctat ttacaacaat agtgctatag tagaaaacaa atgaataagg
     9961 ttacttaaag aggtgaatac gatgaaactg atcaaactat gggaagcaga tttaaagaaa
    10021 gcttatcagc tacaaactag ctttggacca aatgagagtg gatttatcaa caatgcttat
    10081 ggctatacat ttgctgaatt tttagattat gtaaaaaaat gcgaaaaaac gtctttagga
    10141 atcgatcttc ctgagagtta cgttcccgca accgtcttta ttttagaaag tgatgaacat
    10201 gagtatgtag gaatttttaa tttgcgccat aaactgaacg aaacattaag aaacggcgct
    10261 ggccatattg gttacggcat ctcccctaat tatcgtaaaa aaggatatgc cacacaagga
    10321 ttagcattag tactacaaga ggcaaaaaaa atcggcattg atgaggcact tttgtctgta
//
LOCUS       DAPBCF010000078        10202 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.080, whole genome shotgun sequence.
ACCESSION   DAPBCF010000078 DAPBCF010000000
VERSION     DAPBCF010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.080"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..297)
                     /locus_tag="RD508_002563"
     CDS             complement(<1..297)
                     /locus_tag="RD508_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737090.1"
                     /translation="MENENRTDWTLPRKNLNPKTKQPYKRGRNWWIVVYPESLPENWK
                     EIISTEPVAISPLHDKDVNADGTKKKPHYHIVFNRIRQKSPILYRWVMNAVRYEG"
     gene            complement(421..576)
                     /locus_tag="RD508_002564"
     CDS             complement(421..576)
                     /locus_tag="RD508_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein repA"
                     /protein_id="HDT7737091.1"
                     /translation="MVEVEKKKVTLSLPVESNDKLEKMAQKYGMTKSGLVTFLINQAD
                     DKGTIFK"
     gene            complement(1120..2331)
                     /locus_tag="RD508_002565"
     CDS             complement(1120..2331)
                     /locus_tag="RD508_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003672456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HDT7737092.1"
                     /translation="MSFAVARMQKVKSGNLVGVGNHNQRNTDNHSNKDIDVERSHLNY
                     DLVNRTENYKRDIEQFINDNKSSSRAVRKDAVLINEWIITSDNPFFKDKDDKEIKDFF
                     DTAKSYFADKFGDNNIRYAQVHLDETTPHMHLGIVPFNDEHKLSAKTVFNRQALQAVQ
                     DELPKYLNERGFELERGEKGSERKNLTVPEYKKAKDELKEITTTLEQRKSEVLALSND
                     KAPTIKKESLDLKDETKTVKVPSGETIGIGKLRHEFMKNEERKTGNVIIPESKLNAVI
                     KSYEELYKANEKLKNYAETDLPKEITRVKEKYRELAKDYNRLVRKSNQNIETLEELEK
                     ENKSLKNEIKGIYKGFNQFMENTLGATVGQAKKLMNNLMSEVKEFVKGGEFEKIHRNE
                     TKTRDRDELSR"
     gene            complement(2584..3231)
                     /locus_tag="RD508_002566"
     CDS             complement(2584..3231)
                     /locus_tag="RD508_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-8 chloramphenicol O-acetyltransferase"
                     /protein_id="HDT7737093.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKEFDITLLKSMIKN
                     KGYELYPALIYTIVNIINQNKVFRTGINSEGNLGYWEKLNPLYTVFNKETEKFSNIWT
                     ESNVSFNSFYNSYKSDLLEYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNS
                     RFLLPIITIGKFYSKNNKIYLPVSLQVHHAVCDGYHVSLFMSEFQNIVDSVNEWI"
     gene            complement(3567..3800)
                     /locus_tag="RD508_002567"
     CDS             complement(3567..3800)
                     /locus_tag="RD508_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737094.1"
                     /translation="MSKELKKLVADLQGNMDVVGEFMDSPQSVLDKYNVQGKERTVML
                     AKDSEGLNKLGFSSQLVEGALSGAHSQRCHAPI"
     gene            complement(3852..5063)
                     /locus_tag="RD508_002568"
     CDS             complement(3852..5063)
                     /locus_tag="RD508_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HDT7737095.1"
                     /translation="MRILSIFFTNDRKCIIASMLSKTGNYRLYYSLYPFEKKDMICER
                     SFMIVPIGIKKGKLIYKEKNQVNHFYVPNCKASGFLNNVRSIDYNTLLHDTYKNLSLT
                     VTNDKGGNIVFVNQEKLNIPVHFTVKNCYFLDNKTLILLCSSTLNSSMLVYYSIPERE
                     LNYLKMTSQLTFPLSFFEHQIIGEKKIPCLTHINRSDDTVLICLHGGPKYHYNHEYLD
                     LIFDFYHNFNNICLVNFPGSTGYSQKYENELIGNGGVVDVEAVKSVVSYYDSQGFKIK
                     IYGESYGAYIAICLSQFINFSIARIVSVSGFTNLFYMYLCSDSRNLIEKYFSDYRKFS
                     PEKNLAMKELLPIRFLHGSEDKTCPIAQINYFVKKYEGMHLTVLDGFSHYEVDIKKEK
                     IRNKRIVRLLK"
     gene            complement(5075..5881)
                     /locus_tag="RD508_002569"
     CDS             complement(5075..5881)
                     /locus_tag="RD508_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7737096.1"
                     /translation="MMPSQFREQHYLGIKGLKIIVKNELNAFLRNKGLIISQLVQPIL
                     YYIFIVLGINSFVTNIAYEGKTISYADYALTGILGILIISQMTQTIYRITIDKRYGLL
                     ALKRQSGVSPFYYIIGMSMYPTIGICIQSSVLYIIATLFGSSIGLINYLAGIIVVIIV
                     LYFWTSIAALITMKINDYQRRDSIISFIITPLGFTAPAFYLITNVPTFIKVIGYFNPL
                     TYQLYAIRSIVFATPANSLLIIVLVFLATLIMISISSFAVSKMSLVLTER"
     gene            complement(5883..6803)
                     /locus_tag="RD508_002570"
     CDS             complement(5883..6803)
                     /locus_tag="RD508_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7737097.1"
                     /translation="MKKNVLDIKDLSLKYGKKFAIKDINLSIFTGEIVALVGHNGAGK
                     SSLFNIIAGIQTPTTGSVEFDQDFIEKRLFATIGFSPQTQVMDWYTNVWDNVYLGSQL
                     AGIDAKTGKLLTEKALDLLSISDLKNKPVDALSGGQQQRVQIARSIVHQPDFYLLDEP
                     TTGLDAETSNRLLSFLKKEAAKGKSVFVSSHDLHLLEEFCDNLVLIDKGRVLYAGDLK
                     NFLIENAPKKSYQITTDRSIHEEIIHKLNEKGIAVTGLDNFQYRFILNQESDLTQLFM
                     DTKEFFRIDEIVKETMSLRDLYIHYREGGL"
     gene            6866..7156
                     /locus_tag="RD508_002571"
     CDS             6866..7156
                     /locus_tag="RD508_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737098.1"
                     /translation="MAERTIDQKIQNVLKKFIDSYKDNRSLTPQTSYLFYDFIILSYH
                     NKRKNRYSISTLSEILLAEGIEANLLINIYAHSLYVLALNDGKQIYDKGFLI"
     gene            7153..8460
                     /locus_tag="RD508_002572"
     CDS             7153..8460
                     /locus_tag="RD508_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HDT7737099.1"
                     /translation="MNYYDRVKRQHGIYFNLLSKYNLHPLKKDHWIYAYKQMYNKKKQ
                     GFKIHLSANTNNAINIAKKFLNYNETKQLDFKIVSTLAKFDIQNTGALGYSQIGKLIT
                     IYPNDDDEFLYTLNELELIFKSDLSPEIPSDFRYMLSSVVNYRYGEIVVDPNFNDLRD
                     KTIPNDIIIPVDDYYIPRLKEIPKHLLLLKVIKKTGKGGTYQCLDLKRNELVLLKQGI
                     HQGDLTIDNVDTINLLSLEKRSLLKLNKENQFPTFIDDFYLENSYFLEINYLNKETLY
                     QFMKKEPLSPEKIKSIILKIISVVKLLHEKYNIIHRDISFDNVLIDEHQEISVIDFEF
                     SYDLKQWNPPSIIMGTPGFYNANRLNIDQYTDVYSIISLLYFMDNFDLYCNYKNDHNK
                     LTLQRNSIDKGTSSFYFIYLQAQYHSARYSLDMLEHDLRTLSV"
     gene            complement(8751..9743)
                     /locus_tag="RD508_002573"
     CDS             complement(8751..9743)
                     /locus_tag="RD508_002573"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737100.1"
                     /translation="MSKSNKRGDLEYARLFHTSVKEYKAVVDVLEETTDENRVTKLKI
                     KMMLLRKYISDRENVQIKSIVPKLKTLIPGQATIIAQYYTDFTNETNKKMIHVNALGE
                     EQDVRAVFNDITYGYYLHADFDKVERLRNTNQTFLWVMVDGFIESIEEIIFKLDNLIL
                     DQELTSEMSEPVLPCEPVIRYKEVPENKKNKQSGVWANLIADEITDDALKDIVASMSE
                     DDFKCMLKAQEFMDALGKETVPTVETMRSIVLEERIQDWEDFTRIHEIIAGLKDCGLS
                     TRVEYGENGQEASIKLFREVGEGFIISDPQLVHVPTIELCLNSSGEWRVFGFAI"
BASE COUNT         3374 a         1873 c         1292 g         3663 t
ORIGIN      
        1 accctcatac cgaacggcat tcatcaccca cctatagagg atgggcgact tctgcctaat
       61 tctgttaaaa actatatgat aatgcggctt tttctttgtt ccgtctgcat taacatcttt
      121 atcatgtaat ggactaattg ccacaggttc agttgaaata atctctttcc aattctctgg
      181 caaactttca ggataaacaa caatccacca gttacgacct cgcttataag gctgtttagt
      241 ttttggattt aaattctttc taggcaatgt ccaatctgtt ctattttcat tttccatatt
      301 tttctacacc ttcctagtta ctctactagg aaaacaaggg aaaatttgat aaacttgagt
      361 tgcgaaatca aagaaaacca aatcttgcga gcccttgcta tcttcctagc agggcttttt
      421 ttatttaaaa atagtcccct tatcatcagc ttgattaatt aaaaatgtaa ccaaacctga
      481 tttagtcatt ccatattttt gtgccatttt ttctagtttg tcattcgatt caacaggtaa
      541 agataaagtc acttttttct tctcaacttc aaccacaaaa tgcacctcaa ttctcttcaa
      601 aatctctttt acactgtaat tatattatac atacgacagg aatacaagat tttacaaaaa
      661 actttttttc acctcgaaat aggtgcttaa aacgttcata taaaggtatt tacaagacat
      721 ttaatctttt tatctatttg gacaatggac aatggacaca tggggggtgt cgtagtgccc
      781 ccatgttttt tcgctccaaa aattcccatg ttttttcgcc ccctgctccc actaaatttc
      841 caaataataa aaccgtgggc tattcgccca cacccaacaa gcgcaaagcg cttgaccttg
      901 cctctgaaaa gcaacttgat aactgcattc gtttctttcc gtcgtcttag caaaagctaa
      961 acaactcaaa aaaagagatc aagggtaaat acactcacta cgttcgccct tgacctcttt
     1021 tatttcgctg ttttttacgc atttgccgac gaaaagtaaa caatatgcag aattacccta
     1081 gttttgataa aaaagcgctt agaacgcaaa tatgagcttc taacgactta attcatccct
     1141 atctcgtgtt ttagtttcgt ttctatgaat tttttcaaac tctccacctt ttacaaactc
     1201 tttaacttcg ctcataaggt tattcatcag ctttttagct tgtccaacag ttgcaccaag
     1261 ggtattttcc ataaactggt taaaaccttt gtaaatgccc ttaatttcgt ttttaagcga
     1321 cttattctct ttctctaatt cttcaagtgt ttcaatattc tgattactct tacgtaccaa
     1381 cctattgtaa tctttcgcta attcgcgata tttctcttta actctagtga tttctttagg
     1441 taaatcagtt tccgcataat tttttagctt ttcatttgct ttatatagct cttcatagct
     1501 tttaatcact gcatttaatt tactttcagg gataattaca tttcccgttt ttcgttcttc
     1561 atttttcata aattcatgtc gcagcttacc aatcccaatg gtttcgccac ttggtacttt
     1621 gaccgttttc gtttcgtctt ttaaatctaa actttctttc ttgattgttg gtgctttatc
     1681 gttcgataac gctaaaactt ctgactttcg ctgttccagc gtggtagtta tctcttttaa
     1741 ttcgtccttt gcctttttat attcaggcac cgttaaattt ttacgctctg accctttttc
     1801 gccacgttca agctcaaaac cacgctcatt taaatacttt ggcaattcgt cttgtaccgc
     1861 ttgtaaggct tgacgattaa aaacagtctt tgctgatagc ttgtgttcgt cattaaacgg
     1921 cacaattcct aagtgcatat gcggtgtcgt ttcgtctaag tgaacttgag cgtagcggat
     1981 attattatcg ccaaatttgt ccgcaaaata tgatttcgca gtatcaaaaa aatctttaat
     2041 ttctttatcg tctttatctt taaaaaatgg gttgtcagaa gttatgatcc attcgtttat
     2101 taatacagca tcttttctga cagcacgact acttgattta ttgtcgttaa taaattgctc
     2161 aatatctcgt ttataatttt ctgtccgatt gaccaaatca taatttaaat gcgaccgttc
     2221 aacatcaata tctttgttgg aatgattgtc tgtatttctc tgattatgat tacctacccc
     2281 gactaaattt cctgatttta ccttctgcat tctcgccact gcaaatgaca tgtaaacact
     2341 cctaacttcg gcacaacttc catgtaaagt ataacccact agacttattt actacgtttc
     2401 ataagtcatt aatgcgtgtg ctctgcgagg ctagtttttg tgcaagcaca aaaaatggac
     2461 tgaataaatc agtccataag ttcaaaacca aattcaaaat caaaacacca gcaaccaaaa
     2521 atggtagttg ctataaactt ataaatatca taattactta agtttatgaa agttatttta
     2581 gatttaaatc cattcattta cactatcaac tatattttga aattcactca taaataatga
     2641 aacatggtaa ccatcacata ccgcatgatg aacttgcaat gagactggta aatagatctt
     2701 attattctta ctataaaatt tacctattgt aataattggc aataggaatc tactattatt
     2761 accaatattt aaattaaatg aactaaaatc aatccaagga atcatcgaaa taggaactgt
     2821 gttttcaggt attggttttt taggaaacat ttcattttta tctttatatt caagtaagtc
     2881 actcttataa ctattataaa aagaattaaa actaacattt gattctgtcc aaatgttaga
     2941 aaatttttca gtttctttat taaagactgt atataaaggg tttaattttt cccaataacc
     3001 caaatttccc tcactattaa ttcctgttct aaatacttta ttttgattta taatatttac
     3061 aattgtataa atcaaagcag gatacagttc atatccttta ttttttatca tacttttaag
     3121 taaagtgata tcaaattctt tagtaacact gtaagttgtt tgttgattga aataatgatt
     3181 aaaatattct tttctatccc aagtttccaa attaataata ttaaaagtca tatataattt
     3241 tcctcctaaa tttcatctta tctctttgta tttaggagga ataatcctct gattttttca
     3301 tatattgtgt cacctcttaa acgttaatta tactaaagta acattttgta taaaacaaag
     3361 ttactttact tccaaaatct aaattcacgt tgccaaaaat caatctgctt ttgcaattgt
     3421 ttttcgttcg cttttaaagt cgatttcatt aaacttcaac tttgcaaata aatcagacta
     3481 tttaagtata attgattgac ttaacaatgc tattagcaca ataatatccc tctacataaa
     3541 taaagtagag gaatatggaa atatttttat attggtgcat gacatctttg actgtgagca
     3601 ccagataaag ctccttcaac taactgactc gaaaacccta gtttattcaa accttcgcta
     3661 tcttttgcca acatcacagt tctttcttta ccttgtacat tgtatttatc caagacactt
     3721 tgaggactat ccataaattc accgacaaca tccatatttc cctgtaaatc tgcaaccagt
     3781 tttttcaatt ctttagacat aatactgcac ccccgtaaag tttataatta tatgataaca
     3841 ttcatcagta attacttcaa taatctgact attcttttat ttctgatttt ttcttttttt
     3901 atatctactt cataatgaga aaaaccatct agtactgtca aatgcattcc ttcgtatttt
     3961 tttacaaaat agttaatttg tgcaatcgga caagttttat cttcacttcc atgaagaaat
     4021 cttataggta ataattcttt cattgccaga tttttttctg gagaaaattt cctataatca
     4081 gaaaaatact tttcaataag gtttctcgaa tctgaacaaa gatacatata aaataaattt
     4141 gtaaatccac taacagagac tattcttgct atactaaaat taataaattg agagagacag
     4201 attgcgatat acgctccata actctcacca tatattttta ttttaaatcc ttgagaatca
     4261 taatagctaa cgacagattt tacagcttca acatcaacaa cacctccgtt acctattaac
     4321 tcattttcat atttttggga atatcctgta cttccaggaa aattcaccaa acaaatatta
     4381 ttgaaattat gatagaaatc aaagattaaa tctaagtatt catgattata gtgatattta
     4441 ggtcctccat gcaaacatat cagaactgta tcatcacttc tattaatgtg agttaaacaa
     4501 ggaatttttt tttcaccaat tatttgatgt tcaaaaaaag aaagagggaa agtaagttga
     4561 ctagtcatct ttaaataatt taattctctt tcaggaatac tgtaataaac tagcattgag
     4621 ctattcaaag ttgaactaca taaaagaatc aatgttttgt tatcaagaaa ataacaattt
     4681 tttacagtaa aatgtactgg aatatttaat ttttcttggt ttacaaatac aatattgcct
     4741 cctttatcat tcgtaacagt taaactcaaa tttttataag tatcatgcaa cagagtatta
     4801 taatcaattg atctgacgtt atttaagaaa ccagaggctt tacaattagg cacataaaaa
     4861 tgattcactt gatttttttc tttatagata agctttcctt tttttatacc tattggcact
     4921 atcataaaag atctttcgca tatcatatct ttcttttcaa atggatacag cgaataataa
     4981 agtctataat tacctgtttt acttagcata cttgcaatta tacattttcg atcattagta
     5041 aaaaaaatgc ttaggattct cactcagtca ccttctatcg ttctgtcagc actaaactca
     5101 tcttggaaac agcaaatgac gaaatactta tcataatcaa tgtggctaaa aatactaaaa
     5161 cgatgattaa taaactattt gctggtgtag caaatactat agaccttatt gcatatagtt
     5221 gataagttaa cggattaaag taaccaataa ctttaataaa tgtagggaca tttgtaatta
     5281 aataaaatgc aggagctgta aaccctaatg gagtaataat aaacgaaata attgaatctc
     5341 ttcgctgata atcattaatt ttcatcgtaa tcaacgcagc tatggatgtc caaaaataca
     5401 agacaattat cacaactatt atccctgcca aataattgat taaaccaatt gagcttccaa
     5461 acaaagtagc tataatataa agtacactag actgaataca tatgcctata gtaggataca
     5521 tactcattcc tataatgtaa taaaatggtg aaactccact ttgacgtttc aaagctaata
     5581 gaccatatct tttatctata gtaattcgat aaattgtttg agtcatttgt gaaataatca
     5641 atattcccaa aatcccagtt aaagcataat cggcataaga aattgttttc ccctcatagg
     5701 caatatttgt gacaaaacta ttgataccta agacaataaa aatatagtac aagatcggtt
     5761 gaaccaattg tgatatgatc aatcctttgt ttctaagaaa cgcatttagc tcatttttta
     5821 caatgatttt taatcccttt attcctaaat aatgttgctc cctaaattga cttggcatca
     5881 ttttaaagac ccccttctct ataatgaatg tataagtctc ttaatgacat agtttcctta
     5941 acaatttcat ctattctaaa gaattctttt gtatccataa acaattgtgt taaatcactt
     6001 tcctgattta atataaatct atactgaaag ttgtctaatc ctgtcacagc aatacctttt
     6061 tcatttaact tatgaataat ttcttcatgg attgatctat cagtagtaat ctggtaactt
     6121 tttttaggcg cgttttcgat caagaaattt tttagatccc ccgcgtataa aacccttcct
     6181 ttatctatca aaactaaatt atcacaaaat tcttctaata aatgtaagtc atgtgacgac
     6241 acaaaaactg atttcccttt agctgcttct ttttttaaaa atgacaacaa ccgattagat
     6301 gtttctgcat ctagtcctgt tgttggctca tctaacaaat agaagtcagg ctggtgaaca
     6361 atggagcgcg caatttgaac acgttgttgc tgtcccccag atagtgcatc tacaggttta
     6421 ttttttaaat ccgatatact taataaatct aaggcttttt cggtcaataa ttttcctgtt
     6481 tttgcatcta ttcctgctaa ttgactgcct aagtaaacgt tatcccacac atttgtgtac
     6541 caatccatca cctgagtctg cggtgaaaaa cctatagttg caaataatcg tttttctata
     6601 aaatcctgat caaactctac tgaacccgtc gtcggagttt gaatcccagc aataatattg
     6661 aataagcttg atttacctgc tccattatgc ccaactaatg ctactatttc accggtaaat
     6721 atggaaagat taatgtcttt tatcgcaaat ttttttccat atttaagact taaatctttt
     6781 atatctaata catttttttt cattactaaa ctccttttct aaggtataat taattaaatc
     6841 ttacttaaaa gagagggatt ctaatatggc tgaacgaacc atcgatcaga aaattcagaa
     6901 tgttttaaaa aaatttattg attcctataa ggataatcga agtctcacac cccaaacctc
     6961 ctatttattt tatgatttta taattctatc ctaccataat aaaagaaaaa atcgttacag
     7021 tatttctacg ttgtcagaaa tattattagc ggaaggtatt gaagcaaatt tattaataaa
     7081 tatatacgct cattcccttt atgtactagc attgaacgat ggcaagcaga tatatgataa
     7141 aggattttta atatgaacta ctatgatcga gttaagaggc agcatggtat ctattttaat
     7201 ttattatcta aatataactt acatccccta aaaaaagatc actggattta tgcatacaaa
     7261 caaatgtata acaaaaaaaa acagggattt aaaattcatt taagtgctaa tactaataat
     7321 gccattaata tagctaaaaa atttttaaac tataatgaaa caaaacaact agactttaaa
     7381 atcgtttcta ctctagcaaa atttgacata caaaatactg gggcattagg atattctcaa
     7441 ataggaaagt taatcactat ttatccaaac gatgatgatg aatttcttta tacacttaat
     7501 gagctagaac tgattttcaa atcagactta tctcctgaaa tcccttcaga ttttagatat
     7561 atgttaagtt ctgtggttaa ttatagatat ggagaaatag ttgtagaccc taatttcaat
     7621 gaccttagag ataaaactat tccgaacgat ataattatac ctgtggacga ttactatatt
     7681 cccagactaa aagaaattcc taaacattta ttactattaa aagttataaa gaaaactggt
     7741 aaaggtggaa catatcaatg ccttgattta aaaagaaatg agctagtact attaaaacaa
     7801 ggtatacatc aaggtgattt aacaatcgat aatgtggata ctattaatct tttatcttta
     7861 gaaaagagga gcctcttaaa actaaataaa gaaaatcaat ttccaacgtt tattgacgat
     7921 ttttatttag aaaactctta tttcttggaa ataaattatc taaataaaga gactctatat
     7981 caatttatga aaaaagaacc gttgtctcct gaaaaaataa aatcaattat tttaaaaatt
     8041 atttcagtag ttaaattgct ccatgaaaaa tataatatta ttcataggga tatttcattc
     8101 gataatgttt taattgatga acatcaagaa atttctgtga ttgattttga attttcctat
     8161 gatttgaaac aatggaatcc accttctatt attatgggta ctcctggatt ttataacgca
     8221 aaccgattaa atatagacca atatacagat gtttacagca ttatcagtct attatatttt
     8281 atggataatt tcgatctata ttgtaattat aaaaatgacc acaataaatt aactttacaa
     8341 agaaattcaa tagataaagg tactagttct ttttatttta tctatttaca agctcagtat
     8401 cattccgcta ggtattcact agatatgctt gaacatgatt taaggaccct aagcgtttaa
     8461 attgttatag ttaaactcaa ctaatctgca caacttaaat gtcctctatc aataaattat
     8521 tctattgaat aacgctaagt ccaacagggt atactctgtt ggactaaaaa tacaaacaca
     8581 tatgtgataa aagtatattt ttattatcaa ccctattcca tgctgtttca aataaattta
     8641 agttagattt tattcttgca atatgtgaga accagtagat tcattaaata cgagggtata
     8701 tatttgagaa ccatgctatt ctattttatc cttatggaag aagattctgg ctaaatggca
     8761 aaaccaaaca ctctccattc gccgcttgaa ttaagacata actcaatagt tggcacatgt
     8821 acgagttgtg gatctgatat tataaatccc tcgcctactt ctctgaataa ctttatactc
     8881 gcttcttgcc cattctctcc atactctact ctcgttgaca acccacaatc ctttaaaccc
     8941 gcaataattt cgtgaattct tgtaaaatct tcccaatcct ggattctttc ttctaaaact
     9001 attgaacgca ttgtttcaac tgttggcaca gtttctttcc ccaacgcatc cataaattct
     9061 tgtgctttaa gcatacattt aaagtcgtct tcagacatac ttgcaacaat atcttttaaa
     9121 gcatcatcag taatttcatc cgctataaga tttgcccaca cacctgattg cttatttttt
     9181 ttattctctg gtacctcttt ataccgaata acaggttcgc atggcaaaac tggttcactc
     9241 atttccgaag taagttcctg atccaggatc aaattatcca atttaaaaat tatctcttca
     9301 atactttcaa taaacccatc gaccatgacc cacaaaaaag tttgattcgt atttcgcaat
     9361 ctttcaactt tgtcaaaatc tgcatgaaga tagtaaccgt aagtaatgtc attaaacaca
     9421 gccctaacat cttgttcttc acctagagcg tttacatgaa tcatcttttt atttgtttcg
     9481 ttagtaaaat cagtatagta ctgagcaata attgtagctt gaccgggaat caaggtttta
     9541 agtttaggta cgatactttt tatttgtaca ttttctctat cagatatata ttttctgagc
     9601 aacatcattt tgattttgag ttttgtcact ctattttcat cagtcgtttc ttctaaaaca
     9661 tccactacag ccttgtattc ttttactgaa gtatggaaca atctcgcata ttcaaggtcg
     9721 cctcttttat tactttttga catttctttt atcctcttac ttttctaaaa ttaaactaac
     9781 ttttaattct ttcaattttc ctctatctaa gttatactat atgcaaacaa ggagctgcgc
     9841 tttaacatag ccccttaaag cgtagtccgt ttaagacggc agctgaattt aatacgtaaa
     9901 taaatccgtc aattctcgct aaagtctatg acgggtttat tttttgttgt ttttgctaat
     9961 tgttagcata atgccaacta aagcaaggac gaatgatcca aattgaatca tcaaaccaat
    10021 tgcttcagca acagacaaaa aatgctactc ccttctacga agtaggaaaa tgcacataag
    10081 catcaccccc tgagtagcca ccgtcataaa ctcactacaa atatattata gcatatctag
    10141 ctaaatcctc ttattataat tttgctcatg tttagaattc atattttcct tcatcatcat
    10201 tg
//
LOCUS       DAPBCF010000079         9327 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.081, whole genome shotgun sequence.
ACCESSION   DAPBCF010000079 DAPBCF010000000
VERSION     DAPBCF010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9327
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.081"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            316..1101
                     /locus_tag="RD508_002574"
     CDS             316..1101
                     /locus_tag="RD508_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7737101.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            1114..1965
                     /locus_tag="RD508_002575"
     CDS             1114..1965
                     /locus_tag="RD508_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HDT7737102.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(2089..2541)
                     /locus_tag="RD508_002576"
     CDS             complement(2089..2541)
                     /locus_tag="RD508_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7737103.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLMQTDISLVS"
     gene            complement(3006..3374)
                     /locus_tag="RD508_002577"
     CDS             complement(3006..3374)
                     /locus_tag="RD508_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HDT7737104.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            3524..4006
                     /locus_tag="RD508_002578"
     CDS             3524..4006
                     /locus_tag="RD508_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HDT7737105.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSEHMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLLNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            4043..5053
                     /locus_tag="RD508_002579"
     CDS             4043..5053
                     /locus_tag="RD508_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HDT7737106.1"
                     /translation="MISYPLLERNTTIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGINLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(5168..5881)
                     /locus_tag="RD508_002580"
     CDS             complement(5168..5881)
                     /locus_tag="RD508_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737107.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSSDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPTHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
     gene            complement(6071..6661)
                     /locus_tag="RD508_002581"
     CDS             complement(6071..6661)
                     /locus_tag="RD508_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HDT7737108.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            7184..7855
                     /locus_tag="RD508_002582"
     CDS             7184..7855
                     /locus_tag="RD508_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HDT7737109.1"
                     /translation="MEPKDKYLDYARVNKDKFIETIIKGKIPDDEKDAVFMAGSPGAG
                     KTEVALGLAENYDNHVVIDADYFRAQFPEYNGKNSSVFQKASSWLVEQSLKYVLEHGY
                     SFILEDTFAILSAEKNIIRALKNNFRVTIFYVYQDPKVAWDFTRKRELAEGRHVPKEM
                     FINAFFKSRENIEKVKNRHPEVVLHIMIKDYQNDISEVHYAADNIQLVLPNTIYFKRV
                     GGGIT"
     gene            7852..8013
                     /locus_tag="RD508_002583"
     CDS             7852..8013
                     /locus_tag="RD508_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737110.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMKYVADEANRK
                     QRKLVGLDK"
     gene            8497..9267
                     /locus_tag="RD508_002584"
     CDS             8497..9267
                     /locus_tag="RD508_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HDT7737111.1"
                     /translation="MNPTLITKKELLKKLDISTGVLADLIRNGMPKEGEMFNLDKIIT
                     WRENWSKNILGELEVGRVYTNKEISEKFKCFKQGGMRRSHQTNTLVLFSDQTGSNVYK
                     DKWLNGILQYTGMGLKGDQVLDKNQNKVLANSKSNFVKIHLFETFKPKEHTYLGEVYL
                     AGQIYTVNEKDSSGNSRKVYKFPLALINQEQLIEDKDIYNQEENQTRHIRNLSDAKLE
                     EEARKVSNYNKKMAAKYVNEEEFCFSKTKIYKRTRGAS"
BASE COUNT         3209 a         1445 c         1762 g         2911 t
ORIGIN      
        1 gctgtgacaa aagtcttgtc acagcctttt tttccaaata aatggttttt cagaagtagc
       61 ttcttcggaa ataagccgaa atttcacaaa aatttgagaa gtaatttttg taaattactt
      121 cttatttctt gaagctggcc acttctgtca caacctcttt ctttatagaa ataaaaggac
      181 actagcaatt catgaaaacg attgctagag cgtatcattt gctttagact atatatcttg
      241 gtgtacactc actttaagac ggaaataaaa gttatccgta ataacaggtt taggtatgaa
      301 aaaggagtgg gtactatgta taaggaatta gaaaacaaag tcgcagtagt aactggtggc
      361 tcaaagggga ttggaacagc gattgctcaa cgattcggga aagaaaaaat gaatgtagtt
      421 gtcaactata actcggataa agaaggagca gaaaaagcag tcaaagcaat cgaagaggca
      481 ggcggaaaag cagtctctgt acaagcagat gtcagttctg aagaaggaat acagcgttta
      541 cttgatacgg ctttagaaaa ttttgggaca ctggacgttt ggattaataa tgctgggatg
      601 gaaaatcagc atccaaccca tgaacttagc cttgaagatt gggaaagagt attaaaagtc
      661 aatttgactg gcgtttttat cggaacgaaa gcggctttaa attactttac agagaatgat
      721 aaaaaaggaa atatcatcaa tatgtcttct gttcatgaac aaatcccatg gccaacgttt
      781 gctcattacg ctgcttcaaa aggcggagta aaactattca ccgaaacggt agcaatggag
      841 tacgcaccaa agggaatcag aatcaatagt ataggacctg gtgctatccg tacacctatt
      901 aatgcggcaa aatttgatga tcctgaacaa aaagaactct tggaaagtat gatcccacta
      961 ggacgcgtag gtgaaccaaa agaaatagcg gcgacagctg catggttggc ttcagacgaa
     1021 tccagttatg ttacaggtat tacactattt gcagatggtg ggatgacttt atatccttct
     1081 ttccaaggtg gaaaaggata agggtgaata aaaatgggtt tattgattgc attgatcccg
     1141 gcagttgggt gggggatcca gccactgatt ttgaaaaaga ttggtggcag accaacaaat
     1201 gagatattag gaactggtat tggagccgtg ctcgttggct tacttgttca attattcgct
     1261 tctccagctg gtatttcagt gactacattt ttgattagtt tactttctgg tgcattctgg
     1321 gtcatcggac aaacaggaca gtatacatct ttcaacttga ttggtgtttc taaaacgatg
     1381 ccaatttcga ctgcattaca gttagtcgga acctcattga ttggtgtctt cgcttttgga
     1441 gaatggtctg gaagtatggg aaaaatcatt ggtgcagcag caatcattct tcttgtattt
     1501 ggttctgctt taacggcaat cagtgatgat cctggaaaaa aaggcggtat cacaaaagga
     1561 atcagtctat tagcatcaac aagtattggt tattgggttt acagtgcatt gcccaaacta
     1621 gttgatgcaa gcggactttc cattttcttt ccgcaaatga tcggtgtctt tttaggggca
     1681 gtgatttatg tgattttccg aaaaccaacc gcattttctg aagacaagag ttggaaagca
     1741 acaatagttg gagccatctt cagtgtgtca gcattggctt atattttttc agcaaatgaa
     1801 aatggggttg ctactgcata tatcattaca cagctaaacg tagttatctc tacattaggc
     1861 ggtatgtaca tcctgcatga aaataagaca ccaaaagaaa aaaaattaac gattatcgga
     1921 ttattgctga tcgtagtagg aagcatggtc acggtcttta tttgaggata aagatggtaa
     1981 aatctcattt attaaaaaaa tatttgtttg aaccaaacag taagtactta taaaaaaata
     2041 gcgctagaat ttccaacatc tctggaattt ctagcgcttt ttaattgttt aagatacaag
     2101 tgaaatatct gtctgcatca ataatttttc attgatccat tgactaaagt ttacgacata
     2161 attgaagtta ccaccgatta gtatctccgc atgattgtct ttataaagat cgtattgtaa
     2221 aagacggtct tttttatttg cgtaaacatc gttatggtac tggactaatt gttctcggaa
     2281 ttgattgatt gctgtaaaat cacgatactg aaggttgaaa cgcatcgtga ttggtgcatt
     2341 tagcatgaat cgctgcattt cttttgctgc ttcctctgct tgatctccgt ataggaactc
     2401 aaaaagatta cgttcagaaa atttccattg cccgccaacc tttgttcctt ttagttttcc
     2461 ttcatgaaga taatttctga tagaacgtgt agtaacacct aattgttcgg ctaattcatt
     2521 tactgagtaa aaatctttca atgttcaccc tcctatgtga atggttctac tgacttagtt
     2581 gatatttgct taatcacgaa atgtagaaag aacgatttta attaaggtca ttgtaaaaat
     2641 caagtcagaa aattctaact tttctttctc taaagaaatt cgttctctcc taaagtgata
     2701 ttatatttaa atatacctga aaataatggg cagtattatg aaagatcact gatattttct
     2761 cgtatttttt ccttattcaa aagttttgca ggaaaattgc tgaaaaaata attttactaa
     2821 gtggaaaatt caaagccatt caatcagtga tttttttcag cacaagaaag actccttata
     2881 aaaatagcag atactttgtc aattaagtgt ttaaccaggg atgataaaaa ggataggatt
     2941 gaacaaaacc tgtataagct gatgaatagt ttcctcgcca gtaaaaggtt tattcgtata
     3001 aagctttatc gccaaaattt atcatgacct tttttatctt caatattaaa tgaaatcaat
     3061 tgttcaatca attcccagtt gattacactt ttccaaggaa ctttgatgac gttatctgta
     3121 tatacgtagc ctgcttcttg gatatttttt tcaagggcac gaatcgctgc tttttccggt
     3181 gcgatagaaa aatgattttt agcaaaacta aatgcaataa taaaggtacc atggtcagta
     3241 aacataggtt ggttccattt tacagttgtg tctagctggg gatacgtttc tgttatctta
     3301 gcaaaaaggt ctttgatctt ttgttgatgt tctttttctt tgatctgatt gatgatcggc
     3361 tgaaattttt ccattctaaa acgcctccat taagtggttt gatttatttt accagaaaaa
     3421 caatagttat gtataaaaaa cgaacaaaac acaagtaatg ttgtaaccgc tatatttata
     3481 tgataagatg tctcaaataa taaaatagaa aagagacata aaaatgattg acttggcaaa
     3541 gaaattctta cacgaaaata tatattttga gttgtatcat catcgagcca tttatacaaa
     3601 tgaagatgct ttggtaataa agaaagaaca aggatttaca ggtacagaga ccaaaagctt
     3661 attcttaaaa gataaaaaag ataataacta cgtatatctg acttttacta cgaaacaaac
     3721 ggatttcaaa gcattgggga agatcgtcgg taaaaggctt tctattgttt catcagaaca
     3781 catggaagaa caaacgggac aaaagcaggg cgctgtttct ccgtttggtt atgaaaaaca
     3841 gattccgatt attattgatg aagagctctt attaaatgaa aaacttgttt ttgcaccagg
     3901 tagaccagat caaacgatgg tcatccaaac ggttgactta aacaaaatca tccagctact
     3961 tgagatgccg atatttttga tgccggcaaa cgaaaaaaac aattaaccaa gtaaaatagt
     4021 gcatacttgg aggtgaagca acatgataag ttatccatta ttagaaagaa atacaacgat
     4081 tggggttact gcaccatcct caggcgtatc agaggaacac cattcgttac tcgaatcagc
     4141 tttaaagaga atggaagaaa aatctttcca agtagttact ggaaagacgc tttggacgca
     4201 agataaggaa aaatcaggtc cagcaagaaa acgagcagat gaattcaatc aaatgatgca
     4261 agatgaaaat atccaaatga tctttccgcc ttggggagga gaattattga ttgagattct
     4321 cgattttgtc gattttgatg ctctacaacc aaaatggata gtaggttatt cagatattag
     4381 tacgttgcta cttgctgtca cattaaaaac agggatagcc actgcacatg gaatcaacct
     4441 tattgattta agaggagagt acttggatga aacgacagca atgtgggaaa gtgtactgaa
     4501 aacaagagaa ggagaatcga ttctacagca accttctgaa aagtatcaaa aagagtggcc
     4561 ccatgagcat tcatcatctt ctgttttcca tctcactgaa ccaacaaatt ggcaatcagt
     4621 cagcggagat gcagtaagga tgaagggacg attattaggt ggctgtattg atacgatcag
     4681 tcatttaatc ggtacccctt atggagatgt ccaatctttt aaaagaaagt ataatgatgg
     4741 aaagccgatc ttgtggtttc tagaaaattg tgagctatcg tcagttgatt taagaagatc
     4801 acttgttcag atgaaactgg caggatggtt tgatggcagc tcggggatca tgttcggtag
     4861 aagtgcagca gaggatttgt tagattataa aatgaaggat gtatacgaag atctgtcaaa
     4921 ggaattaaaa ctaccgatct tgtatgatat tgattgtggt catgtaccgc cacaactgac
     4981 attgatcaat ggtgcctatg cagaagtagc ggtagaagat agaaaagcga ctgttttgca
     5041 aacgtttatt taaaaaattt tttcctgcct tggagtttat caaagaccaa caaatctaaa
     5101 tagaaaagaa aatgaaagaa gctgacagta ttttgccagc ttctttttgt atgatctatt
     5161 agaaatttta attatccata actatcacat tgatcagctg tttcacatca tttggattac
     5221 ctgtaggaat agctactaca gatgcattat caataatttc ttgagttgtt tctctaatga
     5281 acgctggata agatgtttga tctgcaggca tttgccaatg tgtaggaact ggataactag
     5341 tgattgtccc gtcatggtta cttgaataca ctaaaactcc ctggtaactg tatttcccag
     5401 tgagcataac cacatctttc ggatagactg cactccctgc atcataaggg gcgataggtg
     5461 ttcctgcagg ataatgaata acatgtagtt cgaaatcact cgatgtatct ctaaaagtat
     5521 tacctctaat agctagccaa acacgtgcgt actcaatttg tagatcagaa tatcctgcta
     5581 acggatctat tgactgagaa gactgtgagg aagttgtgtc tattgttgaa gaagaaatat
     5641 ttgtctcaac tgtactacta gatgtagaag aagtattggg ctctgagact ttactgcttg
     5701 ttgaagatgt attcgtttca gtagaagctg atttctgagt acttgatttt tcagctgaac
     5761 tggtttgtct gattgaactt ttgtctgtgg tcgcagatgg atcactattt tctttactag
     5821 gagacgtaca tcctacaagg aataaagaga ccaacaataa aataaaacct aactttttca
     5881 tataaaatac ctcattattt ttttaatacc agtatagcgt aatcctgaat ttttgaatcc
     5941 gtaaaacctt gtctatgaat ataaatagag tatatcttct ttgataaatg tcagaaaaag
     6001 tgtgacaaat aaccatcagt aaaattactt gtcatactat tgagaaggag tatttaattg
     6061 aagagaatga ttaggagaaa ggatctccgt actttttata gtaatcatag aatccaagtt
     6121 tgtatagacg aatcgttttt tctcttattt cttctgtttc aaaatggact gcttgaagaa
     6181 tcaagtctgt gaattctata ggagctgttc cattcgcagt aatcaaatta cgatctttca
     6241 cagcttgttg ttctataaaa tcttctttat tctgataatt ttccgattct aaccaaggaa
     6301 attgcgcatt tccggtgtgt ttgtaacctt gcaataatcc gctctgagct aaataatcaa
     6361 ctgccccaca aatagcagct actggtacgt ctgtttttaa caatttatcg attatttgat
     6421 ataaatgatg attttttatg tcccatgaat tgccaccgat cataataaaa aggtcaactt
     6481 tttcaggtat ttgttcgatt aagtaatcga tttttgtttt taatcctcca atggaagtga
     6541 cctctgattg gatagaagca gttttgtttt gccatccctc tttttggttt agtgtgctag
     6601 taatataagc accttcccaa tcggcatatt cctctaatag aaacgtaatc gcagttttca
     6661 ttttcaagct ctcctttact atctatgaca aggacaacag ttttaacata cagacattca
     6721 ttaaatttgg atagcgacag cgaaaacaac aattcttaag ttttagacag agtatacaga
     6781 cagtcaactt aattaaatac gaactaaata aaaatgacag gtaatcattt ttgtttacca
     6841 gcattataac attttgcata catggatgac aaaagaacca attcccactt gcttgagtac
     6901 aatcttaaaa gaaactggaa ggcaaaaagt aattatagaa acgaaaaata aatcatatcg
     6961 ggcactcaga catgaaaaca accctagaaa tatataacta gtccaatgaa aaaacagcga
     7021 atgccgtaga aaacaaggat tctgcgtaca ttcatatctc attttgcgag catatctgct
     7081 attactgtga ctaaatgtta atatggttaa aatgaccgtt atatttttta tataaatatc
     7141 gtataattag tatgaatata gaagaaggaa agaaggtgca atcttggaac ctaaagacaa
     7201 gtatttagat tacgctaggg tcaataaaga taaatttatt gaaacaatca tcaagggaaa
     7261 aatccctgat gatgaaaaag atgcggtatt catggctgga agcccaggag caggtaaaac
     7321 agaggttgca ctaggtttag ctgaaaatta tgacaaccat gttgtgattg atgcggacta
     7381 ttttagagca caatttccag aatacaatgg aaagaactca agtgtttttc agaaagcttc
     7441 ttcttggtta gttgaacaat cattaaaata tgtactggaa catggctatt ctttcatact
     7501 agaggatact tttgctatcc ttagtgcaga gaaaaatatt attcgagccc ttaaaaataa
     7561 ctttcgcgtt acgattttct atgtttacca agatcccaaa gttgcctggg atttcactcg
     7621 aaaacgtgaa ctagctgaag gacgtcatgt gccaaaagaa atgtttatca atgcgttttt
     7681 taagtccaga gagaatattg aaaaagtcaa aaatagacat cctgaagtag tccttcacat
     7741 aatgattaag gattatcaaa acgacatttc tgaagtgcat tatgcagcag ataatattca
     7801 attagtacta cccaatacaa tatacttcaa aagagttgga ggaggaatta catgactgag
     7861 aaagaacaag tacaacaaat cgtgaagaag tataataaaa gtatcgctga tttatcagaa
     7921 aacgcctcag cgaaagaatt taaaacagta atgaagtacg tagcagatga agcaaatcgt
     7981 aagcagcgaa aactagttgg gttggataaa taaatttttt aaaccatatc cttgtaaagt
     8041 tgagtttttt gttttaatga attaagacta ttaaatagat aattattgta acttaaaaaa
     8101 cacagctaaa aattagttgt gttttttatt aggtttactt ttctggtata aaaggaacta
     8161 gctacttttt caaaatttct aaatcattca atatgtagcg cttactaaat tattcgccat
     8221 aaaattttat aattggatca ctcattgttt tacctaagtc atatttaagt aataaccggt
     8281 gtttttacat aagaagactt ggggtatttt ttagtttgat tagctctgat atacctataa
     8341 agaatatgct aaggtaagaa tagtaaaaat tcacatagat gaggtataat aatgatgttt
     8401 ttatatatta cagataactt gacacaaaat gagttttttt cgatttttca agttatctaa
     8461 tgcaattata ttgatatcat taggagctgc attgttatga atccaacatt gattactaag
     8521 aaagaattac taaaaaaatt agatatttct actggtgtat tagctgattt aattagaaat
     8581 ggcatgccaa aagagggaga aatgtttaat cttgataaga ttattacatg gcgagaaaat
     8641 tggtctaaaa acatattagg tgagttagaa gttggtagag tatatactaa caaagaaatt
     8701 tcagagaagt ttaaatgttt caaacagggt ggaatgagaa gatctcatca aactaatact
     8761 cttgtactgt ttagtgatca aacaggaagt aatgtttata aagataagtg gttaaatggt
     8821 attttacaat ataccggtat ggggctaaaa ggggatcaag tattggataa gaatcaaaat
     8881 aaagttttag ccaattcaaa aagtaatttt gtaaagattc atttatttga aacatttaaa
     8941 ccaaaagaac acacgtatct gggagaagta tatttagcag gacaaatata tactgttaat
     9001 gaaaaagata gttcgggcaa cagcagaaaa gtatataaat ttccattagc tttaataaat
     9061 caagagcaat tgattgaaga taaagatata tataaccagg aagaaaatca aactagacat
     9121 attcgtaatt tatctgatgc taaattagag gaagaagcaa gaaaagttag taattataat
     9181 aaaaaaatgg ctgcaaaata tgttaacgaa gaggagtttt gcttctcaaa aacaaaaata
     9241 tataaacgta cccgtggtgc tagttaattt taatatccta aagaatatct caaagttcct
     9301 tcaaaacgtc gttgtgctcg acttaat
//
LOCUS       DAPBCF010000080         9310 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.082, whole genome shotgun sequence.
ACCESSION   DAPBCF010000080 DAPBCF010000000
VERSION     DAPBCF010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.082"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            85..222
                     /locus_tag="RD508_002585"
     CDS             85..222
                     /locus_tag="RD508_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737112.1"
                     /translation="MILLKKEYEKFYDRLIYSLQLPKKLNRQLQKTYETKSTEEWESY
                     C"
     gene            664..1044
                     /locus_tag="RD508_002586"
     CDS             664..1044
                     /locus_tag="RD508_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HDT7737113.1"
                     /translation="MSEQNQNLASNYSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVASG
                     DAQRLSENLKIMQKELQKIWQQLR"
     gene            1026..1940
                     /locus_tag="RD508_002587"
     CDS             1026..1940
                     /locus_tag="RD508_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDT7737114.1"
                     /translation="MATIKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            2180..2869
                     /locus_tag="RD508_002588"
     CDS             2180..2869
                     /locus_tag="RD508_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737115.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFL
                     GFIFYLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYVKDTKI
                     EEACSDLFGDTNPWFASEEEKKEKQQSVTYERYEILLQQATNMQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(2990..3076)
                     /locus_tag="RD508_002589"
     CDS             complement(2990..3076)
                     /locus_tag="RD508_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDT7737116.1"
                     /translation="MFELFICPLLVGVCVSLFSYWLNNRNKK"
     gene            3720..4457
                     /locus_tag="RD508_002590"
     CDS             3720..4457
                     /locus_tag="RD508_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDT7737117.1"
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEI
                     FTFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDK
                     VNETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKG
                     HWFVKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAY
                     KGNKIGSLQIYFEENIPSITLDNWLEK"
     gene            4485..5024
                     /locus_tag="RD508_002591"
     CDS             4485..5024
                     /locus_tag="RD508_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HDT7737118.1"
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKV
                     VLRSGVLQLASNLGNQRLLYRLHEYEQENDKNVYISSKNVIVNELLDKLREENEFLRE
                     QLSLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTTILSEET
                     ESIEKHTKKKKQKWWQLWK"
     gene            5040..5210
                     /locus_tag="RD508_002592"
     CDS             5040..5210
                     /locus_tag="RD508_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737119.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            complement(5524..5985)
                     /locus_tag="RD508_002593"
     CDS             complement(5524..5985)
                     /locus_tag="RD508_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7737120.1"
                     /translation="MEDLGSKLRELRVKKGYTQEYVARKFNVTRQTISKWENNKTTPD
                     IETLKKICEFYSTNINSILNEDNLKNKQNNLLVLTAIIFNIFVTILGLFELIQMNFFS
                     FTHGIFTWFALSGLIVIDILNYFYIYYSYLKNEKFFYTIFFPLVILIILLS"
     gene            6118..6492
                     /locus_tag="RD508_002594"
     CDS             6118..6492
                     /locus_tag="RD508_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HDT7737121.1"
                     /translation="MKKFLCLSALMGVLLTSGGIVSATEALNLDVPEDHTAIYGGGME
                     ATEEGFSSSKLRYAAGGGDFNCGVNGFKVYANYYHARAKHSATAKNGRGGQVRSVQKA
                     GVRAYATCNATLTGNTGWWNVY"
     gene            6546..8672
                     /locus_tag="RD508_002595"
     CDS             6546..8672
                     /locus_tag="RD508_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737122.1"
                     /translation="MLKKINAVLSLFVCITILFFSTNVINGIKTSEALYKNTAEIHMQ
                     YKDDMDFNSYINALYEISTQENINISQYSFTAVNQLTILATNPNANKHWKFSKKNILA
                     RNDSKVHYTNNKNSKYQLKLPNNFLNINIYPFSHVENIGLSEILYVQGNSNKLIPVLK
                     KYGTPTISNINQSDTFQINTNIVLVICYLSIFIVITTIIFAFSKMKEITLKKMLGYNS
                     FDTIKDSIKELNLLFCSLIITFILSIFLSIYYSNENFFLSFLLCSIFHFIISFLFIIV
                     TLSIYHLSSIKNYLKNSRPLKLNLCILNICLFLSMILLLIASTKVINIHNEAENNSLK
                     YWERTTNLYKTNITNQLNRNNTVEENNYLKKASKFVYKIQKNYKTFIIAPYNYATIQE
                     NNKEFFIGQKVYPNFEDYVSQPAGAGICVDLNYLKYYNPISFEESTDLNLINSDPLTT
                     YILVPKKYKEYAKMIEKNYLEDIQFRLEDSPPQAPYKTPNLKNLKIKLIFVNNNQKYF
                     SFNTLYGKAKDNYTITDPIVRVINPEITESLFWGNILTSDGGLFFDQKHTSNQNFFNQ
                     INPYIKEFNLENIINFSYSVFQETGELLSQKKVNKLNAYLQYLLILGLFIIINFQMIF
                     VSFTINSKKIALKKIFGYSPISQVLDLCLLPFTIELFATMCFQLIFSKNTYLYFIIFM
                     IFLINLITSIIIYKKNSFKYFKENIL"
     gene            8669..9289
                     /locus_tag="RD508_002596"
     CDS             8669..9289
                     /locus_tag="RD508_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7737123.1"
                     /translation="MILSVENFTLSINKKKIKQNWNFSISEKDFIIVTGKSGSGKTTL
                     LNNLSLIDKQYTGNLFYFEKKVSKHDIQRLRRNHISYLFQNYALLENQTVQYNFELAK
                     KFNSNISNDHIYNLLTDFSLPKDILKEKIFLLSGGEQQRIALIRNMLKPFDILFADEP
                     TGNLDKENSTFIMNFLKNLTEKEKKAVVLVTHDLNVLNYGTNIIEL"
BASE COUNT         3602 a         1411 c         1449 g         2848 t
ORIGIN      
        1 actagcacca cgggtattta ttttatattc catctctcct atcccaaaat ttaaataatc
       61 acttaataaa aaggaggcac ccaagtgatt ttattgaaaa aagagtatga aaaattttat
      121 gatagactta tttattcttt gcaattgccc aaaaaattaa accgtcaatt acaaaagact
      181 tatgaaacta aatcaactga agaatgggag agttattgct agatttttgg tagaagtaac
      241 aaaaagtgga catattatca taatgactcg ccgaaagtct gataaaaaat tggctaaaaa
      301 tattgctgaa tgtttaataa aactatcagt tttagctaaa tagttagtag tttacacaaa
      361 aaagcattta tgttttttgt tgcaaagcaa caatttcatc ttcggtgaaa taagcgaaac
      421 tttacaaaaa gtggctagca tttgctagct ttttttgtat tgtggagcgt gggttttgag
      481 ggggattcaa gggggagctt gcgccccttt gacaagcggt tatttgcacc aaatacggag
      541 gtatttggct agcaaatata gagcttgcca aaccctttta gtgagcttta ctcattgtac
      601 ctttttaggt acaatggtat tgcgaacgat acgtccgtag gacgtactga aagggtggga
      661 cttatgagcg aacaaaatca aaatttggct agcaattatt ctaaaaaata tacctatcga
      721 tccgagccaa aacaaatcag ttttcgagtg agcgaatccg aatttgcaaa gctgaagcaa
      781 tcggctgaag ctttgcaaat gagtgtgccg gctttcgtga aagccaaggc acaaaacgcg
      841 cgtctggtga caccgaaagt ggcgccagac attgcccagg caatcgcgcg cgatttagcc
      901 aaagctggag ggaatatcaa tcaaattgct aagtggtgca atacacacca acatgacgtt
      961 gcttctggtg acgctcaacg tttatccgaa aacctaaaaa tcatgcaaaa ggagctacaa
     1021 aagatatggc aacaattaag gtaagccgaa ccacttcttg tagtcgtgca attaattatg
     1081 cagaaccacg agcaaccatt aaaacaggaa taaactgtga cgtcgattat gccaaaagtg
     1141 aaatgaaaca aattcgcatg ctgtatggaa aagacgaccg tgtacaggca cacttattga
     1201 ttcaatcttt tcgaccagga gaaattaccg ctgaaaaagc taatcaacta ggggcagagt
     1261 atgcaaaaaa aatagccccc gatcaccaaa tagctattta cacacataca gacaaagacc
     1321 atattcataa tcacattgtc attaactccg ttaatctgga gactggaaaa aaatttcaag
     1381 ctcatggtca agcatttcta aacaaatgtt atgacctaaa tgacgagatt tgtcttgcac
     1441 ataacttacc aatcactgag cgaggaaaga agccagaaaa acgaaccatg tctgaaataa
     1501 aattaaaaga aaaaaatgaa cctgtttgga aagacgaaat tcggattgcg atcgatcaaa
     1561 caatgaaaaa caaaaaaacc agaacctatg accaattttg taattccctc aaaacattgg
     1621 ggattcattg cttcaatcgc gggaaaaatt tcacttacga attgatccac aaaaagaaaa
     1681 aagtacgatc caacagacta ggaaaggact acgaaaagga gacgatttta catgagctgg
     1741 acagacgaga acgaacctat aaccaacagc gaaccaacga gctacgaaga gctcgagcta
     1801 gcattcgcga aactgcagaa gaagtacgaa gagaacaacg aactcttacg cctgaacaac
     1861 cggaaattag accggctcga agaaaccatg aacaacacgt tgaaagagga acagaccacc
     1921 aacaagaatt atcgctctaa aacgttaaaa gacatagaaa acgaaataaa gaaacaacgt
     1981 gcttttctcg ttccttatac gcaagaaagg atacaaacta cgattgattt acaagttaaa
     2041 aaactccatc aagagctatt agaccagcga aataaggaac agaaaaaggt gcttactcaa
     2101 cgatcattgg attttcttgc ccccttatgt tgcttagtcc tgacactgtt cgcattttgg
     2161 ttagtatggg gaggctaaaa tggcatttta tttaccctat ctactcattt ttgttagtat
     2221 ttcaggaagt atttggctca tctataaaat ttttcaaaca agatattcat taaaaggctc
     2281 taaaattcga tttaagcgat ttttctttct tggctttata ttttacttga taatcgtttc
     2341 aagcggctta ttcggcgttt tagagggaaa taagcgcgtt tctagaagta ttttattagg
     2401 aaatgtcact caaaagtatg aatcagcgcg tgataaaaag aaaaaagagc aagcattagc
     2461 acaaaaaatg gaagagttta ccacttgtta tgaggaaatg aacgatattt ttgtgaatca
     2521 agaaaaacgt ttgacggata aaaacatgga aaaactcact cgtctttatc aaaacttgcc
     2581 agaaaaacag caaaaagagg ttcaagacaa ctatgagcga accaaaaaag acgtgcaata
     2641 tgtaaaagat acaaagatag aagaagcctg tagtgatcta tttggagaca caaacccttg
     2701 gtttgccagt gaagaagaaa aaaaagaaaa acaacaatct gtcacatatg aacgctatga
     2761 aatcttgctt caacaagcaa ctaacatgca aaatccgaca aaaaaagaaa ccgccttaaa
     2821 ctatctaaaa agtgtcaagg aatggttaga tcagcaacaa caaaattgaa tttgatttaa
     2881 aatcatgtta aaatgaatgt gcaaatgatc aaacattaga tacacgaaag ccccagagag
     2941 gtcggattct ctggggcttt ttttcaggtt gatgtcgcct ttattgattt tacttcttgt
     3001 ttcggttatt caaccaataa ctgaataaag agacacaaac tcctacaaga agggggcaaa
     3061 tgaacagttc aaacattaga tacacctcct tccagtcgca agactgtcgg ataggcgaca
     3121 agttattata tcttaaaaaa ttaaatttgt gtggtgtttt taagtatcac ttgttttagg
     3181 gttgttaggg cttgccctga ccgcctgtaa ggcgcttctc gactagatta agggaattaa
     3241 tcaagaatta tcttagaacg gcttagacaa gctttcagag cctcacacct cctctttgaa
     3301 caacggtttt agcaaaggag ccggaggcga ctgcgcagta taatatgaga gcatagcgat
     3361 cacacctttt tagcgaccgt agggagcaag ttttccagtt tagaaaaatt cgcgaacctt
     3421 tttggaggaa aaagtaggag ttttttaggc gggaaattca atgtgctttt aagatatact
     3481 gttagatata ctgttagata tactgttaat aataactgtt agggattagc aaccttatgg
     3541 gagagtaagt attgacatag gtagtggggg ataaattgtc acactatggg ggataaattg
     3601 tcacactatg ggggataaat tgtcacacta tgggggataa attgtcacac tatgggggat
     3661 aaattgtatt ttacatcctc ttatgtctat gataacataa tttattgagg tgatttttat
     3721 tgagtaacga tatagttcga tataataatg gattaaattc tgtcccttta agaaaattta
     3781 cccctataga tatggattta ttttggggaa tatgttctaa aatgaaaaga aaaggtacaa
     3841 aagaagaaat ttttacattt aaacaaataa aagaattaat tgattacaat ataaatgcac
     3901 gtggcgaccg ttttgctaat gatttaataa aaatgtcaaa aaaaatcatt actttgtctt
     3961 ttatttatga agacgaaaaa acatatgaac aattaaatct gtttcaaaaa tttaaaatcg
     4021 ataaagtgaa tgaaacatta ttaataaagg tttctgaaga atttgaatat atacttaatt
     4081 caatcggaac taattttact cgtttcgaat tagaaaatat gacaaactta aagagtagct
     4141 acgttaaaga gttatatcgc caacttatgg ctcataaaga cagaagatct aaaaaaggtc
     4201 actggtttgt aaaaatagaa gattttagag ctctattagc aataccagaa agttatcgca
     4261 tgagagatat tgataaacaa atttttgccc aagcgaaaaa agaattttta aacgttaatt
     4321 caactcaccc tgctattttt aaaacttttg aaatcaaaaa aattaaagcc tacaaaggaa
     4381 ataagatagg atctctgcaa atttattttg aagaaaatat accttcaatt accttagata
     4441 attggttaga gaaataatac ctaacaattt aggaggcaat tatcatgcaa cccaaagaaa
     4501 cctttacaat aaaggaatta tctgaattat ttgaaataag taggcaagca atctctaaac
     4561 atgttgataa attagacccg tccttattag ctaaaaatga gcgtggttat aaggttgtat
     4621 tacgttctgg agtattgcaa cttgctagca acttaggtaa ccaaaggtta ctatataggt
     4681 tgcatgagta tgaacaagaa aacgataaaa acgtttatat atcaagcaaa aacgtgattg
     4741 taaacgagtt gctagataag ttgcgtgaag aaaatgaatt tttacgagaa caactttccc
     4801 tcaaagagca aaataattct aatatgcaaa aattactcga ccagcaacaa cagctcaccc
     4861 tacaggcaaa tcaacagatc gaaaaactgc aagaacagtt acaattagct tatacggaag
     4921 aaactccaga agatgaatca actactattc tttctgaaga aacagaatcg atagaaaaac
     4981 acacaaaaaa gaagaagcaa aaatggtggc aactttggaa ataactggag ggaacattca
     5041 tgacaagaaa aaatcttcta ttcggttcta ttttactagg aattctagga ttcagtccga
     5101 tgttattgtc agtaatcaat aaagggaata aacatggtga attgaaattg aatccaaatt
     5161 attacaacag tcctaacgaa gaattgtttg taaaagagac ggataaataa taaaaaagac
     5221 tgctcttccg agcagccagt taaaaaaata atgagagttt attcttgaaa aagcaacgcg
     5281 cttataaagc gctaccaaaa ttttatcata ttttataaaa aataacaatc cagtaaaaaa
     5341 tgactggtaa aaattcacaa agaaacggaa agaagcaact acagaaaatc aagccttaaa
     5401 aagagctttt tacctagacc aattaaaaat cacaaagtga gcgtctctat ccattggtag
     5461 aggggcaact tggtctagtg tacattatgt caactatgca attaaataac taactacttc
     5521 atattagctt aataaaataa tcaaaatcac taggggaaaa aatattgtat aaaaaaattt
     5581 ttcatttttt aaataagaat agtaaatata aaaataattt aagatatcta ttactattaa
     5641 tccagataga gcaaaccaag taaatattcc gtgtgtaaag ctaaaaaaat tcatttgaat
     5701 caattcaaat aaacctaata tagtaacaaa tatattaaaa ataatagctg tcaataccag
     5761 taaattattt tgtttatttt ttaaattatc ttcatttaaa atagaattta tgttagtact
     5821 ataaaattca caaatttttt ttagtgtctc tatatctggt gttgttttgt tattttccca
     5881 ctttgaaata gtttgacgtg taacattaaa ttttcttgcc acatattctt gagtataccc
     5941 ttttttcact cttaattctc ttagcttaga tcctaaatcc tccatttttt ctcctatgta
     6001 aacgattatt tacataaaat tttatcataa aaatactaac gcgccaaaaa agttctttat
     6061 tttataaaac acactaaaat aaaataattc tagtaaaaaa gataggagaa ataagttatg
     6121 aaaaaatttt tatgtctttc tgctttaatg ggtgtcttat taactagtgg aggaatagtt
     6181 agtgctacag aagctttaaa tctagatgta cccgaagacc ataccgccat ttacggagga
     6241 ggaatggaag ctacagaaga aggattttct tctagtaaat tgagatatgc tgctggcggc
     6301 ggagatttca actgtggggt taatggattt aaagtttatg caaattacta ccatgctaga
     6361 gctaaacata gtgcaacagc taaaaatgga cgaggcggtc aagtacgatc agttcagaaa
     6421 gctggagtaa gagcttatgc aacatgcaat gccacactta ctggaaatac tggttggtgg
     6481 aatgtttatt aaaaaagaga gtttaaactc tcttttttat ttacatttga aaggaaattc
     6541 aaaatatgtt aaaaaaaata aacgctgttt tatcactttt tgtctgcatt acaatactat
     6601 tcttttctac taatgttata aatggtataa agacttctga agcgctatat aaaaataccg
     6661 ctgaaattca tatgcaatat aaagatgata tggactttaa cagttatata aacgctttgt
     6721 atgaaatatc tacacaagaa aatattaata tttctcaata tagttttact gctgttaacc
     6781 aactaactat tcttgctaca aaccctaacg ctaacaaaca ctggaaattt tctaaaaaaa
     6841 atatattagc aagaaacgat tctaaagtcc attatactaa taacaaaaat tctaagtacc
     6901 aattaaaact tccaaataat tttttaaata taaatattta tcctttttct catgtggaaa
     6961 atattggatt aagtgaaata ttatatgtac aaggaaactc aaacaaatta attcctgtac
     7021 tgaaaaaata tggaacacct actatttcca atatcaatca atcagatact tttcaaatta
     7081 atactaatat tgttcttgtt atctgctatc ttagtatatt tattgtaatt actacaatta
     7141 tatttgcttt ttcaaaaatg aaagaaatca ctctaaaaaa aatgttaggc tataactctt
     7201 ttgatactat aaaagattct attaaagagt taaacctctt attttgttct ttgattataa
     7261 ctttcatttt atctattttt ttgagcatat attacagtaa cgaaaatttt ttcctatcat
     7321 ttcttctatg tagtattttt cattttataa ttagtttttt atttatcata gttactctaa
     7381 gtatctatca tttatctagt ataaaaaatt atctaaaaaa ttcacgacca cttaagttaa
     7441 atctttgtat attaaatatc tgtctattct taagcatgat ccttctgtta atagcttcta
     7501 caaaagtaat aaatatccat aatgaagccg aaaataattc tcttaaatat tgggaaagaa
     7561 ctactaattt atataaaaca aatattacta atcaattaaa tagaaacaac accgtagaag
     7621 aaaataacta cttgaaaaaa gctagtaaat ttgtttataa aatacagaag aattataaaa
     7681 cttttattat cgcgccatac aattacgcaa ctatccaaga aaataataaa gaatttttta
     7741 ttggacaaaa agtttatcca aattttgaag actatgttag tcaacctgct ggtgcaggaa
     7801 tatgtgttga tttaaactat ctaaaatatt acaatcctat ttcttttgaa gaatctactg
     7861 acttaaattt aataaactct gatccactaa ctacttacat tctagtacct aaaaaatata
     7921 aagaatatgc aaaaatgatt gaaaaaaatt atttagaaga catacagttt agacttgaag
     7981 actctcctcc tcaagctcct tataaaactc ctaatttgaa aaatttaaaa ataaaactaa
     8041 tatttgttaa taataaccaa aagtatttta gttttaatac cttatatgga aaggcaaaag
     8101 ataactatac aataactgat cccatagtta gagttattaa tccagaaata acagaatcat
     8161 tattttgggg aaatatattg actagtgatg gtggattatt ttttgatcag aaacatactt
     8221 caaaccaaaa cttttttaat caaattaatc cgtatataaa agaatttaac ctagaaaata
     8281 tcataaattt ttcttattct gtttttcaag aaactggtga attattatct caaaaaaaag
     8341 taaataaatt aaatgcatat ctacaatatc ttttaatatt aggattattt ataataatta
     8401 attttcaaat gatttttgtt agttttacta taaattcaaa aaaaatagct ttaaaaaaaa
     8461 tatttggata ttcaccaata agtcaagttt tagatttatg tttactccct tttacaatag
     8521 agttatttgc tactatgtgt tttcaattga tattttcaaa aaacacttac ttgtatttta
     8581 taatttttat gatcttttta ataaatctaa ttacttctat tattatttat aaaaaaaata
     8641 gttttaaata ttttaaggag aatattttat gatattatca gttgagaatt tcaccctgtc
     8701 aattaataaa aaaaagatca aacaaaattg gaacttttca atatcagaaa aagattttat
     8761 tatagtaaca ggaaaaagtg gtagtggaaa aactactctg ttaaataatt taagcctaat
     8821 agataaacaa tataccggta acttattcta ttttgaaaag aaagtttcta aacatgatat
     8881 acaacgtcta cgaagaaatc atattagcta tttatttcaa aactatgctc ttcttgaaaa
     8941 tcaaacagta caatacaatt tcgaattagc aaaaaagttt aacagtaata tttccaatga
     9001 tcatatttat aatttattaa cagatttttc tttgccaaaa gatatcttaa aagaaaaaat
     9061 ctttctctta agcggtggag aacaacaaag aatagcatta attagaaata tgttaaaacc
     9121 atttgatata ttatttgcag atgaacctac aggaaattta gataaagaaa actcaacttt
     9181 tataatgaac tttctgaaaa atttaacaga aaaagaaaaa aaagccgttg tactagtaac
     9241 acatgactta aatgttctaa actatggaac taatattata gaattataat ttttacccgt
     9301 gatgctagct
//
LOCUS       DAPBCF010000081         9103 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.083, whole genome shotgun sequence.
ACCESSION   DAPBCF010000081 DAPBCF010000000
VERSION     DAPBCF010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9103
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.083"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..153)
                     /locus_tag="RD508_002597"
     CDS             complement(<1..153)
                     /locus_tag="RD508_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7737124.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWV"
     gene            complement(574..1116)
                     /locus_tag="RD508_002598"
     CDS             complement(574..1116)
                     /locus_tag="RD508_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDT7737125.1"
                     /translation="MINVSEIKTNKPQKYETLLQEKVYAALESLDISYERVETDEVIT
                     MEDCEQVNLKLDMHMVKTLFLCNRQKTNYYLFITSGDKPFKSKDFSKALGISRVSFAS
                     KEDMTSMLQTKIGAATVFSTLIDTKNKIKIIFDKDVTDDRWYGCSDGTTTGYLKISTN
                     EIIAKLLPYTKHQMEIVKIS"
     gene            1238..2104
                     /locus_tag="RD508_002599"
     CDS             1238..2104
                     /locus_tag="RD508_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7737126.1"
                     /translation="MDMNIQKYIAFLKTVELKSFTKAAEALNYSQSGISRMINDLEDE
                     WGVTLLERNRTGLRLTSDGINIYPYVKNLFDEYESMQRKLEELNGIKFGVIRIGTFSS
                     VATHWLPQLILNFQNKYPNIKFELLLGDYDEIEHWILTGRVDFGFLRLPTLPKLSTQF
                     IHQDDFKVIVPKNHFLEKKDSVSLNDLSGLPFILLDKNGNSNITTLFETMDFSPDINF
                     TTWDDYAIMAMVEKGLGVSILPELILQRVQYDLTILDLDVPLYRKIGIAYKEEKNLSL
                     ASKKFLDLLFFE"
     gene            complement(3126..3269)
                     /locus_tag="RD508_002600"
     CDS             complement(3126..3269)
                     /locus_tag="RD508_002600"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737127.1"
                     /translation="MKKYNRSYGEFEEKATRKEFMTVLQWVAEESNRKQRKIAGLDKE
                     EEQ"
     gene            complement(3554..4579)
                     /locus_tag="RD508_002601"
     CDS             complement(3554..4579)
                     /locus_tag="RD508_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase NADP-binding
                     domain-containing protein"
                     /protein_id="HDT7737128.1"
                     /translation="MKTIAVVGGHGQVGKGNVRELTNHGYFVVLMGRNLKKMEVFAQE
                     FLPILEQSEVDLNKFVIPEKLADLDMVIVCLDQTDTQFVEQCQKLGIDYLDISANSDF
                     LKKVNLLPIPEKSKRVIGLGLAPGVTNLAAAAYTKKEPSAQMIVIDVLLGIGDRHGEA
                     AVRWTFEQLNRTYIHPKWAQPIENFVYSRKTDFGPPFGKRRSANFGFADQHLLFSADP
                     SRNYVTFLGLDQNWLTALLRTIKKVGLARLFKNPRVIKSPVWFMKRGLVGDRSFVVKV
                     SNGQVKDPEKIVLFGEEEAKMTAEIAVFVANKILIETLPNGHYHLTELTTMSEILSQL
                     PRLSATE"
     gene            5238..5597
                     /locus_tag="RD508_002602"
     CDS             5238..5597
                     /locus_tag="RD508_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDT7737129.1"
                     /translation="MSDNLFLEVQPEVFKQVPRLKDGFLLTLNDGSNQFSSAEGCCMI
                     GDHFLLVSTQHYIPAYDLTIPCEEATVKTSEYDTTFINGHLVLEVTPSNQTIRLKNES
                     GILDSNVQVYFDSSDAS"
     gene            complement(5670..6488)
                     /locus_tag="RD508_002603"
                     /pseudo
     CDS             complement(5670..6488)
                     /locus_tag="RD508_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341332.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
     gene            complement(6902..7333)
                     /locus_tag="RD508_002604"
     CDS             complement(6902..7333)
                     /locus_tag="RD508_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7737130.1"
                     /translation="MLNKRIANKNDYKLVLEIWEKSVKQTHDFLAEADFNFYKAIIPE
                     NLDEVKLYLWEDNGEIVGFSGVSAEELVMLFLDPDFIGKRYGSQILIELIETEDIKRI
                     DVNSQNKYAKHFYLSHGFEIESEEDLDGFGKPYPITHLVKK"
     gene            7434..7733
                     /locus_tag="RD508_002605"
     CDS             7434..7733
                     /locus_tag="RD508_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737131.1"
                     /translation="MTKIYFMLTSNSGVGSTTIFATRARRNIDDLLAFFSQYYDVSAN
                     YTKDKDMIDLLVLPEPFGPFNNERNLPVIQIPTILFLERDFEKIKTHIDAYLAKK"
     gene            complement(7778..8428)
                     /locus_tag="RD508_002606"
     CDS             complement(7778..8428)
                     /locus_tag="RD508_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HDT7737132.1"
                     /translation="MPKVAVMAGTPIDTRMGADLLNEISCELLEVPISGNPAQQTYFQ
                     TLPVFEKMHQIEVKIKDLQSKKIDLLLVYCNSLSASIDFDFLAKKYSMKIITPFQVYA
                     DLAQKHERIGVLTANGQGAAGIESVLVQHHSTIRVYNVTNLDWVHAVEAKIHPSIIVE
                     QFGLTDSMSFFMKNQVEAILIGCTHFPYFLTEYQSRTRIPCINPDDALIEKVKSIL"
BASE COUNT         3023 a         1586 c         1276 g         3218 t
ORIGIN      
        1 tacccaacga taaatcgtag tatgacaaac atttattcca cgatcatata acaattcctg
       61 aacttcacga tagcttagat tgtaacgcag gtagtaacca acagcaacaa taatgacgtc
      121 ttttttgaat tgtttgcctt taaaatgatt cattactctg tcctctctgt cttttttctc
      181 aattttacac taaaatagat tttttggaaa actttgcaac agaacccttt tattgaaagt
      241 aagaagaaca ggctttttta ttagaggcgt tcaaaattgt ttgagcggtt agcttttatt
      301 ttttagaaat aatttcaaaa gtatttttgt tgtgtaaaga aagttgtgcc aaccacttta
      361 tttttaatgt ttcaggatat ttatggaaat ttagcttatt tgcaccaatc acaatggctc
      421 cgaatgaaac cagtattatc tcatagccaa gattttgaat atcggttaaa acatcatcca
      481 ttttatcgaa agattagata ttatttttac caattgtatt tgttaaagtt gtatttccaa
      541 ctttaattac aatcctgtct ctatgaatgt tcatcaggat atttttacaa tttccatttg
      601 atgttttgta tagggtaata actttgctat tatttcattt gttgaaatct tcaaatatcc
      661 agtagtagtc ccatcactac aaccatacca cctgtcatcc gttacatctt tatcaaatat
      721 gattttaatt ttattctttg tatcaattag tgtgctaaaa actgtagctg ctccaatttt
      781 ggtttgtagc atacttgtca tatcttcttt ggaagcaaaa gacactcttg agattcctaa
      841 agctttacta aaatctttag atttaaatgg tttgtcgcca ctcgtaataa ataaatagta
      901 atttgttttt tgtctattac acaaaaagag tgtttttacc atatgcatat ctaatttcaa
      961 attcacctgt tcgcaatctt ccatagttat cacttcgtct gtttctacac gttcatacga
     1021 tatgtctaaa ctttctaaag cagcgtaaac tttttcttgt aaaagtgtct catatttttg
     1081 aggtttattg gtttttattt cactaacatt aatcaatctg aatccttctt tcacttaata
     1141 tttactacaa agaaacttta tcatgtataa ttacatcaca aaagagaata tatcagatct
     1201 ttagtatgat aaaaccagat attaatgagg tgtaagcatg gatatgaata ttcaaaagta
     1261 tattgctttt ctaaaaacag ttgaattgaa aagttttact aaagcagctg aagctttaaa
     1321 ttattctcaa tcaggaataa gtaggatgat aaatgatttg gaggatgaat ggggtgtgac
     1381 attacttgaa cggaaccgaa caggtctacg tctaacttct gacggaatta acatttatcc
     1441 atatgtaaaa aatttatttg acgaatatga atctatgcag agaaagctag aagaactgaa
     1501 cggcattaaa tttggcgtaa ttagaattgg gaccttttca agtgtggcta cgcattggct
     1561 acctcaactt atcttaaatt tccaaaataa atatccaaat ataaaatttg aattattact
     1621 tggagattat gatgaaatcg aacattggat tcttactggt agggtagatt ttggatttct
     1681 aagattgccc acactgccaa aattaagtac gcaatttata catcaagatg atttcaaagt
     1741 tatagtaccg aagaaccact ttttagaaaa gaaagattct gtttcactca atgatctctc
     1801 tgggttacct tttattctct tagataaaaa tggaaactcc aatatcacta cattatttga
     1861 aacgatggac ttttcacctg atattaattt cactacttgg gatgattatg caattatggc
     1921 catggttgaa aaaggattag gtgttagtat acttccggaa ttaattttac aacgtgtaca
     1981 atatgatcta acaattttag atttagatgt tccattatat agaaaaatag ggattgcata
     2041 caaagaagaa aaaaatttat ctttagctag taaaaaattt ctagatcttt tattttttga
     2101 ataattcatc aaaagtctta gctcaaaata tatttacaat cataaaatca aatcgttttc
     2161 agactatttt gataaaatac gagatagagc ctaatatcat tacctgacca ctaccgatca
     2221 taataattac ttataacaag attgagttta tccgaaacta ttccaaaaga aatttatata
     2281 ctaatcacac ttcactaaaa ttatttcacc aatacaaata ttttcctata agcaagtcta
     2341 aaaaaactgc tataagacaa aaaaatagcg atttacgatt tttttaccac aatcagtatc
     2401 gagtttaata taatagtatt atcaaaaagg gagtgtgatc aacatgcaaa atataaaaaa
     2461 aatactatta gtagaaatga aacaagttga aagaaacgaa gctgttaact gtgttgcagg
     2521 agctatcagc gaaggactag ctagtattga ttttgaagct gctagggtct aatgatatgt
     2581 ctactaaaaa caaatccaaa ggacttatag tatcaactat tattttttca tgctttattc
     2641 tattaggtat ccataatttc agcacaaacc tttcaatccc aaaattatta ttaaacagtt
     2701 tagggatctt cttgtttatc cttttactct ttctttcgat aagagaatta ttcaaacggt
     2761 aaaaactata ctgtttgttg caacaatttt atttatctaa taaaaaaaga tagtcttcaa
     2821 agaaaaagct attcttaaca tatggcattt tcatattttt aattacctat gacgttctat
     2881 gggagattta ttctcattat gatacaaaat aaagttatat aatttgaaga acacttaaat
     2941 agccttagta ttgcacacaa aagccgacta cttcaattta tgatgtagtc ggtctttttt
     3001 aaatattatt tgtactagat actcactatc agtagcttct tgtaaaacag attttaggat
     3061 tacaatttaa aattcattta cttccttttt aggcattttt actaagaaga acagtgggct
     3121 tttgcctact gctcttcctc tttatccaat cccgcaatct ttcgctgttt ccgattagat
     3181 tcttcagcta cccactgtaa aacagtcata aactcttttc gagtagcctt ttcttcaaat
     3241 tctccatagc tgcgattata ttttttcatt atttcctcag cttcttctct ttcaatcaag
     3301 taacttcaca tccaattcgt tttaagtata agtgtctcgc aatataaggt cgatatctgt
     3361 cacagcaaga actattattg taatctggtt gatatagaat tttattacta tagaaaaaat
     3421 taaatactat aatttaatct aaaaaagcta ttgcatacta caacatattt gttgaaatga
     3481 tagaataaaa gaataatttt aacaaattag agaagcttgt ttccattttt catagtgtaa
     3541 aaagtttttc aatttattct gtggctgata aacgtggaag ctgacttagt atctccgaca
     3601 tggtagttag ttctgttaaa tggtaatgcc catttggtaa tgtctctatt aaaattttgt
     3661 tcgcaacaaa taccgcgatt tctgcagtca tttttgcttc ttcttctcca aagagaacaa
     3721 ttttttcagg atctttaact tgtccatttg atacttttac aacaaaagaa cgatctccga
     3781 ctaatcctcg tttcatgaac catacggggc tctttattac tctcggattt ttaaaaagtc
     3841 ttgctagtcc aacttttttt attgttctta acaatgcagt caaccaattt tgatccaaac
     3901 cgagaaatgt tacataattg cgtgaaggat ctgcagaaaa aagtaaatgc tgatcggcaa
     3961 agccaaagtt agcactgcga cgcttcccaa atggtggtcc aaaatccgtt tttcgactat
     4021 agacaaaatt ttcaattggt tgtgcccatt taggatgtat atacgtacga tttaattgct
     4081 caaaggtcca tcttactgct gcttcaccgt gacgatcacc tattcctaaa aggacatcaa
     4141 ttactatcat ttgagcagat ggctctttct tagtgtacgc ggccgcggct aagttggtaa
     4201 caccaggtgc taaccctaaa ccaatgactc tcttgctttt ttcaggaatg ggtagcaaat
     4261 taactttttt caaaaaatca ctattggcac tgatatccaa ataatcaatt cctaattttt
     4321 gacattgttc gacaaactgg gtatccgttt ggtccaaaca aacaattacc atatcaagat
     4381 cagcaagttt ttcaggaata acaaatttat tcaagtctac ttcactctgt tctagaatgg
     4441 gtaaaaattc ttgggcaaat acttccattt tttttaaatt tcttcccatt aaaacaacga
     4501 aatacccatg atttgttaac tctctaacat taccttttcc aacctgtcca tgaccgccaa
     4561 ctactgctat cgtcttcatc tttcttctcc tttatctacc aagttaattc atttttaccg
     4621 ataggctaaa tcgtataaaa actaaccact tttaatcatt attttattct tagttttatg
     4681 tgagataaat taaccatttt aagtttacaa atgtaatcaa tttctattac tttataagta
     4741 tcgtttacat tcgtcaacga tagagcttga aatattttta tttgaaaatt ttgtatttag
     4801 atgattatga actaatacag tgtcggagga tacctatgta tttaaactaa actattttag
     4861 aaaaaccagt aatcctttga attttctatt ggaaaatgaa gtaaaatatt ataagaataa
     4921 cctttaaagt tgggcaacta ttattcaaac atctaaacat actcctaaga gaaatagata
     4981 tataatagac taaggaagcg ttttaaatat tgtagaaaat agagaaaatt tatcagatct
     5041 tcggtttaat ttttacagcg ttaatcgctc ttgatatgaa tgagctctga taaagccgaa
     5101 gtaaattggc gatttgaaaa gttcaattat ttgagaatag aatatttttt atatagaatt
     5161 gagttatagt taagggggaa taggtgtgtt aaataaaatg tcaatttcaa ctgtggaagt
     5221 cgatggtggt cgtgaaaatg agcgataatt tatttttaga agtacaacca gaagtattta
     5281 agcaagtacc tcgtttaaag gatggattct tgttaacttt aaatgatggc tctaatcaat
     5341 tttcttcagc agagggatgc tgtatgattg gtgatcattt tttattagtt tccacacaac
     5401 attatattcc agcatatgat ttaacaatac cttgcgaaga agcaacagtt aaaacatctg
     5461 aatacgatac tacctttatt aatgggcatt tagtattaga ggtaactcca tcaaatcaaa
     5521 caattcgttt aaagaatgaa agtggtattt tagatagcaa tgtccaagtc tattttgact
     5581 catcagacgc ttcgtaaatc tgttctaaat atagttttaa aacctcgaat atttcttata
     5641 tcgaggtttt ttgatgaatt acctagtgtt tacgtgttaa ggaacaatcg atcgagcgtc
     5701 actaaaacac cgtcttcgtc atttgaagga cattgatgct tagcaacttg cttaacagct
     5761 tccgttgcat tatccattgc ataactcaga ccacaatact ccaacatctc aatgtcattg
     5821 cccccatctc caaaagcaac gcactggtca ggattaatcc ccaagcgctc aactaacatt
     5881 ttcaagccga aagttttatg gcactcagaa agaatcaagt ctacagaacc atgaccacta
     5941 ctggtaggta ctaatagccc ggctaatttt tcacggaaca attcaacgta aaattcggtt
     6001 ttttcaacag gcatagtcgg agcaaatttt aaaattttat cttgaacttc tgcaaaatca
     6061 gctacccatt ctaatctatg gtaatagata ttggttagat caaaaaatgc ttgactcacc
     6121 tttcctcttt cacagtaggc actattcaga ccacacatca cattttttac ttcaggatag
     6181 tctttacata aatcaaggac cacctcgatc gcttttctag gcatatcggc tgaaaatagt
     6241 acctctgttt tatctttaac aaaagcacca ttttcagcaa caaaacttaa ttcatcataa
     6301 taatttggaa ataacgatct caattggtag tattgatttc cacttgcaac aacaaattga
     6361 caatcaacag ctttcattca cgataaaaca gccttgaacc ttgggatatc gtatgtgtaa
     6421 tcagtacgag caaatgttcc atccatatct actgctacca actttagatt atgaggattc
     6481 ttattcataa aaacactcct gtcgcctttg atatcttcat tatattgaaa aagtattcag
     6541 acctaaagca gcctattttt cttactccgt taaaaataag aacatttcta atttcagtta
     6601 actatctaga tacatacaag ccattttttg tattaaaagc taccgacctg tctttctcct
     6661 aacccacagg tcagcctaaa tcagtgttga cataagattt ttatcatttt tactttaact
     6721 gattttctat aactggtaca tccttggtca gctagtatca taagttgatc ctaagataag
     6781 caccttatta ctgaatgtaa tacacaaatt tgatctggat aattcataac ctagaaatag
     6841 gccatcaaaa taaaaatatt acttttattc atgttcaatc aggtaataaa ccattcatga
     6901 attatttttt tactaaatgc gttatagggt atggtttacc aaaaccatct aagtcttctt
     6961 cagattcaat ttcaaatcca tggcttaaat aaaaatgttt tgcatattta ttttgactat
     7021 taacatcaat tctttttata tcttcagttt caatcagctc aattaatatt tgactaccat
     7081 atcgcttacc aataaaatct ggatcaagaa atagcataac taattcttct gcacttacac
     7141 cactaaaacc gacaatttct ccgttatctt cccataaata aagtttaacc tcatctaagt
     7201 tctcaggaat gattgcttta taaaaattaa aatctgcttc agctagaaaa tcatgggttt
     7261 gctttactga cttctcccaa atttctaaaa ctaatttata atcattttta tttgctattc
     7321 ttttgtttaa catgctctta ttcccctttt cttataattt taactttatt tgcaagcata
     7381 gttagtcaaa cataaagcta ccgctatatt ttatttaaaa aggagaattc gtaatgacta
     7441 aaatctattt tatgcttact tctaatagtg gcgttggttc taccacaata tttgcgaccc
     7501 gcgctagacg taacattgat gatcttttag cttttttctc tcagtattat gacgtatcag
     7561 caaattatac caaagataag gatatgattg atctattggt gctaccagag ccctttggac
     7621 cgtttaataa tgagcgtaat ttgccggtca ttcagattcc gactatttta tttttggaga
     7681 gagactttga aaaaataaaa acacacattg atgcttattt ggctaaaaaa taaaacaaaa
     7741 aaatcctaag ttattgtctg tgtcaaacca atgcttatta aagtattgat ttgacttttt
     7801 ctattaatgc atcatctgga ttgatacaag gaattctcgt tctggactga tattctgtaa
     7861 gaaaataagg aaaatgagta caaccgatca aaatcgcttc gacttgattt ttcataaaaa
     7921 aactcattga atccgtcagt ccaaattgtt ctacaataat actagggtgg atctttgctt
     7981 ccaccgcatg tacccaatcc agattcgtga cattataaac tcgtattgtt gaatggtgct
     8041 gcactaaaac actttctatt ccagccgctc cttgaccatt agcggtcaac acaccaatac
     8101 gctcgtgttt ttgagccaaa tccgcatata cttgaaatgg tgtgataatc ttcattgaat
     8161 atttcttagc cagaaaatca aaatcaatcg atgcactcag tgaattacaa taaaccaaca
     8221 gtaaatcaat ttttttactc tgtagatctt ttattttcac ttcaatttgg tgcatctttt
     8281 cgaagactgg aagtgtttgg aaataggtct gttgagctgg atttcctgaa ataggtactt
     8341 ctaacaattc acaggaaatt tcgttcaata gatcagctcc catcctagta tcaataggtg
     8401 ttcccgccat tacagccact ttaggcatac tgatcattcc ttcaaaatga atttttgcct
     8461 attatactct aaaaatcaaa tttgaagaat agcgatccgg aagttaaact gaaaattcta
     8521 aagtaattct ttgatttatt tagattcaac ttaacatctt tagtgtacta ataaaaaatt
     8581 cgctcaatat ttctagctat actttatatc ccaatataca taagcttccc tatttttaca
     8641 ggttacaagt gaaaattaaa ctgcttatat tgattgcatt taactactaa ggatgatgct
     8701 tgttgttagt atgtcagaaa aatccaacag tatagttttg tcagcacatt catcattctt
     8761 tcctgtaaaa caaaaagaga gtagacctat tcttccactt catcatcgtt atctaaaaca
     8821 gcaattttct gctgtaaaat agtcataaat tttttctagt agccttctct ttaaactcat
     8881 cataatctca attatctttt tttaagattt gctcaacttt ttccctcttg attattgcaa
     8941 ttcacacctt ataaagtttt aaactaatgg gagacgtcat ctagcttaac ttatagtccc
     9001 tgctccgttt aatctacact tgttatcttg tattattgat aaaagataga ctagttacgg
     9061 attgaaatta ggttgcaatt ctaaaaatcc agtagtctaa aat
//
LOCUS       DAPBCF010000082         8972 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.084, whole genome shotgun sequence.
ACCESSION   DAPBCF010000082 DAPBCF010000000
VERSION     DAPBCF010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8972
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.084"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..543
                     /locus_tag="RD508_002607"
     CDS             <1..543
                     /locus_tag="RD508_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7737133.1"
                     /translation="GKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDP
                     IEARLTYNDGSAQVIDKSTGKDITSEGTLTYDSNSRTLKWEASADFLNNNLLDGREIQ
                     LIFTAKTPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTIL
                     AVSLLLLVLATFGYAVLKFN"
     gene            complement(579..2636)
                     /locus_tag="RD508_002608"
     CDS             complement(579..2636)
                     /locus_tag="RD508_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HDT7737134.1"
                     /translation="MKLLNPKTVIAIGTFAATVALAGSADAASTNVMYRLYNPNNHEH
                     FYTSSTKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVTSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNTLDSAYKGLKKKPAPTVNKTELQALYNQVKSTAKGDFTEGSWNNFQTAL
                     SNAKKVLDDSKASQTQVNNAKNSLDSAFKGLQHKPKPSEYAVTVRHMNRQTGTLLKEE
                     HVSVKAGTSYTAKARTDLTNFEAPQYQVNGNETQTQTINTNTTFTFYYDEVFLVEVKA
                     RPNKVSDTDPNIQELYNYSKSYPVVYGQSITIEAPMFTNFVLDPRESSSNTVTLNNVT
                     SNQGINFAYTHQYNVTVNHINVDTNAVLSTETQTVYEGDSFSTSWKNMTDQNYFLCRN
                     DDSSVTVDKNGQRVINNVDQNRTITFKYKNISLSDLNNYVRQKELAWLNSYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENINSFYLYVD
                     EILSDTGAVNAMVMWKDSAAHNANLLYNNQSIVGLSHAYEVSADGSLSSDNVFISANP
                     IFK"
     gene            complement(2780..2971)
                     /locus_tag="RD508_002609"
     CDS             complement(2780..2971)
                     /locus_tag="RD508_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737135.1"
                     /translation="MYADKEKIEWLLFETGKTAYEISKHSSVAESTIADLIKKKSAIE
                     KMRFDNAAKLTKYAESISS"
     gene            3159..3614
                     /locus_tag="RD508_002610"
     CDS             3159..3614
                     /locus_tag="RD508_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737136.1"
                     /translation="MKKLIMVFTSLIAMIVILGGCGSEKNKQDSQDNGVLKPGTVWKE
                     EVGGLVHNLKIIDDTTWEYSESVWHPEQVQITVEKLKDYKGLERYKVIDSGGVDLFIG
                     KTALIVPYNKDGLETFKFIPTNEKEHRDKSEILKEYSTKSGYKLQKTSE"
     gene            3611..3853
                     /locus_tag="RD508_002611"
     CDS             3611..3853
                     /locus_tag="RD508_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HDT7737137.1"
                     /translation="MIASLFIYPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            3871..4173
                     /locus_tag="RD508_002612"
     CDS             3871..4173
                     /locus_tag="RD508_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737138.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAGVAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGIILAAASIVVSLFGMFGQTPQGL"
     gene            4242..6296
                     /locus_tag="RD508_002613"
     CDS             4242..6296
                     /locus_tag="RD508_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737139.1"
                     /translation="MYFTITGNTKKDKELIKKATKEVGKRASFLPKTIKYSVIETEEQ
                     LHVLGKVLEQESQSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVSQVSEVEVNDEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDLVEA
                     NEEPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWERTKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCIE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMERHGQIQQELQAQIPKWKKEYEIQQQELKEQEEKQRQEEKEREQLELKKREQH
                     LAEQKVAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTAESSMENSKESDPSKAKEGSSDSTVHSNTSESSESNE
                     VK"
     gene            6296..8905
                     /locus_tag="RD508_002614"
     CDS             6296..8905
                     /locus_tag="RD508_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDT7737140.1"
                     /translation="MRIRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGSFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYQDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNIL
                     STAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHQGKK
                     FHEERVKVGYRGFCEINFDCHLEQGDHVCLKYDHRGKEYVAWYEFSQRVLKDEEGNIV
                     YRKKRGETHLPELEKEAVLTLDEDKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHII
                     VSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNMLW
                     DLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENST
                     INSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNHG
                     ETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDIYARRLYHNMH
                     DQIEEEAKENIFIKIVQSLDNSTAQKLLIQFYEEKQIDRLQEYLEKLRQNEEITEVIR
                     KRLLLEAEKAVKE"
BASE COUNT         3114 a         1449 c         1801 g         2608 t
ORIGIN      
        1 ggtaagaagg gtacgccgac agctccttta aacgcaggat ctgaagtaca atatctagtc
       61 acacaaaaat ggcacacaaa aggcgtagac gctgcgtcag atcactacaa acaatttagt
      121 attcaagatc caattgaagc tcgtttgaca tataatgacg gttctgcgca agtaatagat
      181 aagagtacag gaaaagatat tacttctgaa ggcacactaa cctatgatag caattcaaga
      241 acgctgaagt gggaagcttc cgctgacttc ttaaataaca atcttttaga tggacgagaa
      301 attcagctga tatttacagc taaaactcca ttacaatcag aaaaaaatat tgataaccaa
      361 gccgtagtag cagtagataa tgtttctaat aaaacaaatg ttgtgacaat tggggttgat
      421 cctaacttgc cacaagttat tgttcctaaa acaggttcta cacatttagt aacgatttta
      481 gcggtcagct tactattact tgtgttagca acttttggct acgcagttct gaagttcaat
      541 taaacaaaaa aacaaggctg aaaatcagcc ttgtttttct atttgaaaat gggattggca
      601 ctaataaata cgttgtctga agaaagtgat ccgtctgcag aaacttcata agcatgggat
      661 aaaccaacga tactttgatt gttgtaaagc aagtttgcgt tatgagcagc gctatctttc
      721 cacataacca tagcatttac tgctcctgta tctgaaagga tctcgtcaac gtaaaggtag
      781 aaactattga tattttctcc tttagcaccg tagcagccta agctttctaa gagatcttgg
      841 aaagtaccgc cgccaggtcg gtaatgactg aagcttactt gtaattcttt tgcacgaata
      901 tctgcagctt gttgaacgat atcattgaat tgcattgggg caacgccatt ttgttgacgg
      961 tagctattta accaagcaag ttctttttga cgcacatagt tgtttaaatc acttagtgag
     1021 atatttttgt atttgaaagt gatcgttcga ttttggtcaa cattattgat tacacgttgt
     1081 ccatttttat caacggtaac agatgaatcg tcatttctac acaagaagta gttttgatcg
     1141 gtcatatttt tccaagaagt agagaaacta tctccctcgt aaaccgtttg tgtttcagta
     1201 gataaaacag cgtttgtgtc aacgtttata tggttcacag tgacgttgta ttgatgagta
     1261 taggcaaaat tgattccttg attacttgta acgttgttta aagtcacagt gttgctagag
     1321 ctttctctag gatcaagaac aaaattagtg aacataggtg cttcaattgt gatgctttgt
     1381 ccataaacga cgggataact cttactgtaa ttatagagtt cttggatatt tggatcagta
     1441 tccgagactt tatttggacg agctttcact tcaactagaa agacttcatc atagtaaaaa
     1501 gtaaatgtgg tatttgtgtt aatcgtttgt gtttgtgttt cattcccatt tacttgatac
     1561 tgtggtgctt caaagttagt caagtcggtt ctagcttttg cagtgtaact tgtaccagct
     1621 tttactgaga catgttcttc ttttagcagc gttccagttt gtcgattcat atgacggaca
     1681 gttaccgcat attctgaagg tttaggtttg tgttgtaacc ctttaaatgc agaatcaaga
     1741 ctatttttag cattatttac ttgggtttga gaagctttag aatcgtctag tactttttta
     1801 gcattggata aagcagtctg aaaattattc caagatcctt ctgtaaaatc tcctttagca
     1861 gttgatttta cttggttgta caaggcttgt aattccgttt tgttcacagt aggagctggt
     1921 tttttcttta atcccttgta agcagaatct aatgtgtttt tggcactatc cacttgtttt
     1981 tgagtcgctt ttgagtcatt taacactttt ttagcattgt ttaaagcggt ttggaatgcg
     2041 ttccaggtat tgtcggtata gtcacctttt ttagttccct taacgctcgt ataaagagct
     2101 tctaaagctg atttattcac tttgggttta gaggtgtcag caccatacca accaatacct
     2161 tcgtatttcc agccatagtc tttggttaac cattgtactt ctttccaact tgcagtgtag
     2221 tgatgcgaac cagaggtaac acctggaagg aaaaggcggt agatcggttt attatttttt
     2281 tcggcagaac gccatgcagg cccttcataa gtccaaccgt aatttttggt caaccatttc
     2341 acttcatccc aactagctgt gtaatggtga tcacgaaggc ctttattgta taaacgatag
     2401 acaaggtggc caccgctagt cggtgcttcc caagcggggc cttcataatt accccactta
     2461 attttcacta ggtgatcacg ttcttttgtg ctagaggtgt aaaaatgttc atggttattt
     2521 ggattataaa ggcgatacat gacgttagtt gaagcagcgt cagcagatcc agcaagagca
     2581 actgtggcag caaatgttcc aatagctata acagtttttg ggtttaataa tttcatgttt
     2641 tcaactccta ttaaatgatt aaatattttg tttacattca taatatacca cggtataccg
     2701 aggtagtcaa cggtataccg tggaaatttt gaaataaaaa agccgcccta tgaagagtgt
     2761 aaggatggct gtttatatgc tatgaagaaa tggattcggc gtatttggtt agtttggcag
     2821 cattatcaaa tcgcattttt tcaatcgcac tttttttctt tattaaatcc gcaattgttg
     2881 attctgcgac tgaagaatgt ttgctaattt catatgctgt cttgccagtt tcaaatagta
     2941 accattcgat tttctcttta tcagcgtaca ttgcaatgct ccctcttgat tttttcttta
     3001 ttatagctct tttttgtaat aaatcacaat atcaagagga aaagtttcta tagaaaggtg
     3061 ggaaattatg agtatccgtt ccccgtgtat caaaatgagg tttgttgcta ctttcgttat
     3121 ttgatatact aaaataaaac aacgaaagaa ggaatagaat gaaaaagtta ataatggtat
     3181 ttacttcgtt gattgccatg attgttattt taggtggatg tggtagtgaa aaaaataagc
     3241 aagatagtca agataatggc gtgttaaaac caggaacagt gtggaaagaa gaagtaggcg
     3301 gacttgttca taatttaaaa attatagatg atacaacatg ggaatattcc gaaagtgttt
     3361 ggcatcctga acaagtacaa ataacagttg agaagctaaa agactataaa ggattagaaa
     3421 gatataaggt aatcgattca ggtggagtag atttattcat aggtaaaaca gccttaatag
     3481 ttccctataa caaagacggt ttagaaacgt ttaaatttat tccaacaaac gaaaaagaac
     3541 atcgagataa aagtgaaata ttaaaagaat acagtactaa atctggatac aagttacaaa
     3601 agactagcga gtgattgcta gtctttttat ttatcctgaa ggaggaatca cagtggcaaa
     3661 agctaaaacg ccatttgaaa aagccgcgtc taaaatctta gaacgtcgcg gtgtatctga
     3721 aacacagtgg aaacaagaag tccttgaaaa agcacaattt gacctattac ggggaaaaga
     3781 caaggactta gaaggatata tctatcaacg tgaacgtgaa aagcttgttt tcgatgaaat
     3841 tattaaacac taaaaggagc gaacaatttt atgtttgaat caattacaat gaatttttta
     3901 acacaaccga aagtagtagc tgcggttgat atttttagag cattacaaac tgcagcaact
     3961 agcttaaaaa acaatttaat gatttttgcc ggcgttgcgg ccgttgcttc cattgttatt
     4021 ggggggcttt tcttcttatt tggacgaaga ggtgctgaaa acgggaagat gcatgtggga
     4081 tatgtattga tgggggtagg aattatttta gctgccgctt ctattgtggt ttcgttattt
     4141 ggaatgtttg gacaaacccc acagggatta taaaaacaaa atgaaggagt aaaaagtaca
     4201 tagctacttt ttactccttt ttttatgaaa ggagaatact catgtacttt acgattacag
     4261 gaaataccaa aaaagataaa gagttaataa aaaaagcaac gaaagaagta ggaaagcggg
     4321 cttctttttt accaaaaaca attaaatatt cggtcattga aacggaagaa caactacatg
     4381 tattagggaa agtactggaa caagaaagtc aatcttctgt taagttgact ctcacgttac
     4441 atgacacaga aggaaaaata gagaaagctg gtacagaata tgtttttggc ccgctggatt
     4501 atcaaatttc agaaggtttc tatcctacat tgatggattt gatccgcctt gatgtgttta
     4561 aggaaacgga tgaaaccatg agtgtggaag agtcttatcg aaacgaaaaa ctgctacaag
     4621 ttttagaaga agagttagag agcgaccaaa gaaaagttag tcaagtgagt gaagtcgaag
     4681 taaatgatga agtaccatgg gaacgaccaa tctttccaaa gaaggagtca aaagaaaaag
     4741 agacagtcta tgttgacgaa caagctgata ttccgactca gaaatcgata tttgaggaag
     4801 agaacgatgt aatgggtcaa ttggaggtag atccctttga agaaacaatg gaggatgaag
     4861 agacggccga agtagaagtt gatctagttg aagctaatga agagccaaca tggactgaag
     4921 gggattctca ggaatatatt gaaccactta tcagtgaaga agtagagaaa aacgaaacag
     4981 agatacaaaa ggcaactgta tttgattata ttttggatca atatccgcca gagcatgaat
     5041 ggatgaaaga aaaaaataaa ttatttttaa atgagcttta ttcgaaatat caattacccc
     5101 aaacctatca agcattttta gagagtaaag aagaattaat ctcacagggt aaaggcacac
     5161 ttttagaaca gttagagtct gttcaatcaa caaattggca tgagcttgca caagaagatt
     5221 tattagccac ttttgaagaa cgtcaacaag aaacagatca agaaataaat gagtatgcga
     5281 cggaacagtc atctaattgg gagagaacaa aagaggaact aaataaagaa gaacaacgag
     5341 tgattgaaga agaagtacaa aaaattaaag agcgatacga aaagaaacgc gacaatgcgt
     5401 attccttgtg tatagagaaa attaataact ttactaaaac taatcaagaa gctttatcga
     5461 aagaaaaaga aaacttgtta aaagaacgta taaaagaacg aaaagaagag ttctaccgag
     5521 gtttacgtac agataagcta aagattagca aagaattaaa tgaacaactg aataaacttt
     5581 atcaaacaac gactgaagtt cttatggaaa gacacgggca gatccagcaa gaattacaag
     5641 cacaaattcc aaaatggaaa aaagagtatg aaattcaaca acaagaattg aaagaacaag
     5701 aagaaaaaca acgacaagaa gaaaaagagc gcgaacaatt agaactaaaa aaacgtgagc
     5761 agcatcttgc agaacaaaaa gtggcgatag aaaaacaacg gttagagcaa gaaaaggaaa
     5821 aagaagcagc tgctcgtaag gaacgtcaag aacaaatgga tacattgcga caagcacagt
     5881 tgaattatct agcacaacct caaccagtag ctgctgttca aacgccagtg aacaaccaag
     5941 caaatttaac tccttcacca cagcgttcct ttaacggatg gatggtggga tgtattgcaa
     6001 gtttaagctt gcttctaggt ggaggaacag tatttgcttt taatcatatc aatcaatctt
     6061 cacaggcaga ttctgtagcc acaacggcgt caatcaagga agaagcccag gaacaagcaa
     6121 gaaaagagta tgaacaacaa ttggaagaat tattgaatcg taccaatcag tcaacagcag
     6181 agtcaagtat ggaaaatagc aaagagagtg atcctagtaa ggctaaagaa ggatcaagcg
     6241 attcaactgt acactcaaac acttccgaaa gttcagaatc aaatgaggtg aaataatgcg
     6301 tattagagaa acaacgagac gaaaagacaa acgattcaat ttagaaaaga ataggtatct
     6361 ttctcatttc tatcgctata ctccttcagg agaagagcta ccagaaaaac atgacaaacg
     6421 tatttctcaa aagatttttt atagtggctt agcttatctt cctttaaact atgttgttac
     6481 aagaatacca gaagcatttc atcgatttga gattattcca ggaagtttac aaggagtgaa
     6541 tatttttcag ttacaagaaa tgccgcagtt attccatttt gattcaactg gtttttggaa
     6601 tcctttgacc ccaacaacaa gtttaggcac acgtttagtt gtttctacga tttgtgttgt
     6661 tccagctgta cttatgggat tgaaaatgga catgtggttt cgtccgctag cagatgggca
     6721 aaaaggagat aaccgattaa aaacgttaaa ggaaatccaa caaatttatc cgcaaatacc
     6781 agaatcaaag ggaagttttc ctggttatgg cggaatacca attactcatt ataaaaaata
     6841 ctggtatatt cagacggata cagtaaatac ttgtattgtt ggtacttccc gctcagggaa
     6901 aggccagata gaagttttag caaccattga caatttgtct cgtgcagaaa gacaaagttc
     6961 aatggttgtt aatgatccaa aaacagaatt atatgttgct agtaaagatg aactagaagc
     7021 tagagggtat gatgtgtatg catttaatat caccgatcca ctgcaatcaa tgagtgataa
     7081 tccattggca ctcatcgtga aatactggaa gcgaggagac atagacacag cgacacagtt
     7141 aaccaatact ttcacgaata cgatttatta tgatgccaac gcttcagaca ataaatactt
     7201 taacgaaaat gcgcaaaaag ctgtcaatgc gcttattttt gcgttattgg aacaagcgga
     7261 tcagacaggg gattactcca aattaacacc gaataatctc gtcgaacttc tttctgagat
     7321 tggtggtttt aattaccaag atcctgataa tgaattcaag cagctcaatg ctttagatga
     7381 atttatgaat cagttaccac ctggaaacat agcaaaaaaa caatatgggg caacaaaaat
     7441 tggttctgat aaagcgaaag gcaacattct atcgacagcg atcacaggac taaatccatt
     7501 tacactgacg aaaattgcga aaatgacttc tcaatcaacc attgattata agtccattgg
     7561 ttttccgaag tatttggatc tcaaactaca cgagagtctg ttaaaccagc gaattgttgt
     7621 agagttttat catcaaggaa aaaaatttca tgaggaacgt gtcaaagtag gctatagagg
     7681 tttttgtgaa attaactttg attgtcattt agaacaggga gatcatgttt gcttaaaata
     7741 cgatcatcga ggaaaagaat atgttgcttg gtatgagttt tctcaaagag tattgaaaga
     7801 cgaagaggga aatatcgttt atcgaaaaaa acgaggagaa acccatttgc cagaattaga
     7861 aaaagaagcc gttctaacat tagatgagga taaaagtaac ttattagtag agtctattcg
     7921 gatgcactat accgataaac caatggctat ttttatgctc acacctgatt atgatccatc
     7981 taaccatatc attgttagta tttttcttag tcagttgtat aaagaattat ctacgcaatg
     8041 tgttaagact aaaggagata aatgtcaccg taggattcat tttattttag atgaatttgg
     8101 gaatatgcca ccaatggata atatggaagg aatcatgaca gtcacagctg gtagaaacat
     8161 gttgtgggat ttgtttatcc aatcctatca gcaactttat gcgaagtatg gggaacaaaa
     8221 cgcagcgatt atcaaagaaa attgtcagac acatatttat attatgtcga cagacgataa
     8281 taccatagaa gaattttcca aaaaagtggg gaataagacg gttgaacaag agaacagtac
     8341 catcaattca ttaggtatga atactcatat caatcgcaat gttgattcag atcgcatctt
     8401 aactcctgaa agaatttcta cttttttaga aggtgaaacg attgtactcg ctcctttaaa
     8461 acgacaagat ttgaaaggtc ataaaatacg gccgtatcct atttttaatc atggggaaac
     8521 gaatcttcct tatgcttatc aatatattga agatttcaat ccatcgtggg atatcaatga
     8581 tatagacata cattgtacac atgcggactt ggatcttaag gctttacaaa ttgattacga
     8641 ttattttcta cctgatatct atgcacgtcg actttatcac aatatgcacg atcaaataga
     8701 agaggaagct aaagaaaaca tttttattaa aatcgttcaa tctttagaca actcaacggc
     8761 acaaaagtta cttattcaat tttatgaaga gaagcaaata gatcgtttgc aagaatacct
     8821 tgaaaaattg cgtcaaaatg aagaaattac agaggttata aggaaacgac ttttgctaga
     8881 agctgaaaag gcggtgaaag aatgatcatt ggaggaatat tttccggcat tgccgactgg
     8941 tggtcaggct tatttgggga tggggatgca ga
//
LOCUS       DAPBCF010000083         8691 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.085, whole genome shotgun sequence.
ACCESSION   DAPBCF010000083 DAPBCF010000000
VERSION     DAPBCF010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.085"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(83..641)
                     /locus_tag="RD508_002615"
                     /pseudo
     CDS             complement(83..641)
                     /locus_tag="RD508_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302360.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            810..2921
                     /locus_tag="RD508_002616"
     CDS             810..2921
                     /locus_tag="RD508_002616"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012579.1,HMM:NF013070.1,HMM:NF019826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7737141.1"
                     /translation="MNTKDLKLLETIVRSHVTNSQQLKSLVHFSTRQITYSIKKINDE
                     LSLHGLSLIKRSNSGEWLYEANDLQKLLIYMNQAMVFKEGAIPEYINDDLAYSEIRRY
                     SELLFILANPKKVTTQEIMAFIGISKNTARNDFSKIKKELPPDYTLIFDPQNGYMIES
                     SMAKLHTLLLEVFNYLFERHATVNRFESLFSEEREFVGFFIHTYEQTFKLKFSDNSLT
                     KLYYLIGLSLSSFKRRTKGQIDFSYDLQELDEFQMIRSCIDQHYQHAEIAIDYEWLTL
                     LFLSFNTISNEFEILDSRIYQVIMEMITLFQSKSAIRISNKEELTNRLMNHLRPAIYR
                     IRYELPFEIDDLAEIVKENHEVSAVLNFVKESIVPLEAFLRKTIPETELYLISVYFCS
                     ELLNSSIIETPVRKKAIVVCSNGLIMANVMAKTLKEIFPDIQFVASSSVREMDKFVED
                     VDLIFSNQPLKSEIPLYIIQPIMNEEEKNRLRNRVLIDFSTNNISKETRNLTEIIKRY
                     SAVQNEESLQTDIERFLINYANSLIYLDRQSKQAQKISFVELLVSEGIILVSTKQLTW
                     QNAMELSCQPLLKEQVINQNYQTILMSQMADEEAYYFLNNRIAIPHSSPENGVIKGGC
                     SLLISVDPIIFPGNRPIHFISPFAIGKKENYLLAINQLLQLSKDEEYQQEILLCTTED
                     EVRKKIKNFLRRKQYVNNEFS"
     gene            2899..3549
                     /locus_tag="RD508_002617"
     CDS             2899..3549
                     /locus_tag="RD508_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HDT7737142.1"
                     /translation="MSITNFPELTIILRGYSFEEAMFVMEELAAMNTSVGIEVTTNND
                     DFARIITEGNKKFGQQLLIGAGTVLTFSQADQAIAGGAKFLLGPKKFSTPIFSLAKER
                     GVVTVPSAFTPSEIQVMFDEGADIVKVFPAVTVGPTYFKQLAGPFGIRPLMAVGGVTI
                     DNIAAFKKAGVVYFGVGSSMFQKADIQNRNGQAIRKSIQSYLDKLAEAGSEEDESH"
     gene            3536..3988
                     /locus_tag="RD508_002618"
     CDS             3536..3988
                     /locus_tag="RD508_002618"
                     /inference="COORDINATES: protein motif:HMM:NF012579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7737143.1"
                     /translation="MSLIKLEEKNILLNQSFSNQEEYFQKITKKLMTENMVKEGYLES
                     ITKRETTYPTGLYIGERSIAIPHTDYQLSNVTAILVSVLKDSLHFQRMDDPEEMVSVN
                     VIIHLLFDSPDKQPQLLKELMSKVTNQDFLQAIMEAKSKTEVLTAFNQ"
     gene            4005..4310
                     /locus_tag="RD508_002619"
     CDS             4005..4310
                     /locus_tag="RD508_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIB"
                     /protein_id="HDT7737144.1"
                     /translation="MSKKTIIVACASSMITSTMAANKIRKIAKTNGLPEPRILQLKFS
                     EVAGALESNQVDFIVPTGKLQENVTKGIKVIPGTPFVTGVNEEKSESLVLEALKELD"
     gene            4322..5599
                     /locus_tag="RD508_002620"
     CDS             4322..5599
                     /locus_tag="RD508_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010492829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS maltose transporter subunit IIABC"
                     /protein_id="HDT7737145.1"
                     /translation="MNIVIDALNWISSLGPMIMMPIIILILGLFFRIKLNTLLKSALT
                     VGIGFAGVNIIINWFISQVGPSVQLMVKNWGIQTSIMDVGWPARAAATWSFPLAAVMV
                     FIILGINVLMLIFKKTNTVMVDFWSYNHYIFVAALVYYATDKNIILAVIFGAIDAIIS
                     FKLADWTTPLVEDYFELEGVNFPTANSVGWAPLAWLLNKLWDRIPGLNKVDARPEKIQ
                     ERFGFVGEPMFMGFVIGLVIGLLAKEPVDKVLIVGMSTSATMVLTPKMMQILMEGLLP
                     FANSVKKFLNVKFPGNNFTMGVDAALTVANSSAIATGIIMVPITLVLAAILPGNKLLP
                     ISDIAYQAMWLSAWPVAFSKGNIIRGILSTTIITACVLLIATSLAGIHTQLALAGGFQ
                     LPAGMTQISTEDAGTHIIGFILMKIAEFISNIF"
     gene            5618..6766
                     /gene="dgoD"
                     /locus_tag="RD508_002621"
     CDS             5618..6766
                     /gene="dgoD"
                     /locus_tag="RD508_002621"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HDT7737146.1"
                     /translation="MKISKITVYKVKPRWIFVKISTDEGIEGWGEMISGTKTETVVAG
                     AYEIGNRFLVGQNPFAIERLFQEMHRSFFRGGPINGTIVSGLEMALWDIKGKALNVPV
                     YELLGGAARDKIKVYSWIGGDRPSEVVEQAQDRVDRGFTAVKMNATEELHYIDSYEKV
                     AEVVERVASIRERFGDTLSIGVDFHGRVHKPMAKVLAKALEPYHPMFLEEVVLPENEE
                     HFSEVANAVAVPLATGERLYTRWQFKSILQQGAIDIIQPDVALCGGILETRKIAAMAE
                     AYDIAVAPHAPYGPIALAATLQVDSCTPNVFIQEQSLGIHYNKGFDLLDFVKNKEIFQ
                     YKDGFVDLPTKPGLGLEMDEDRVKEIAQEGLVWTNPKWKNYDGTIAEW"
     gene            6778..7680
                     /locus_tag="RD508_002622"
     CDS             6778..7680
                     /locus_tag="RD508_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aryldialkylphosphatase"
                     /protein_id="HDT7737147.1"
                     /translation="MINTVTGPIEAESLGTTFIHEHLYVIPNELRKYEDYTLDDIYHS
                     IAEVMAFKQAGGKTIVDLTPINYGRNPLALKMISEATGVNVAFVTGFHKEEFQPKWLT
                     TLNDDEIFELLYSEITHGVTSQNLLPGAMKVGTSKNEVTLAEQRILAIAGQVQKKTGI
                     PIITHCDGGTMGLEQINCLTKNGAKASNICLSHVDLTKDFHYLAQICETGASICMDHI
                     GRELANHDADRVQLIKRLVDAGYENQICLSGDMGRKKYLPTYGGTPGLTYILTSLKEE
                     LLKVMSEPTFNKMIEMNPINILSK"
     gene            complement(8354..>8691)
                     /locus_tag="RD508_002623"
     CDS             complement(8354..>8691)
                     /locus_tag="RD508_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7737148.1"
                     /translation="DYLLSIDNQLRQSYEVYQELLAAFDAKDFTEFFNLIESLPHSLN
                     DGFKKAICYLKKHTEAITNSLKYPYSNGKLEGKNNLIKVIKRIAFGFRTFRHLRMRVL
                     IQQNICEII"
BASE COUNT         2835 a         1324 c         1776 g         2756 t
ORIGIN      
        1 taaaaaaata tttggcgtca ctactcagtt tgagtaacaa aaccaaatat tatagaaccg
       61 gctttttcag ttttttccct tcacaaacaa catcgatgat tttctcggca tgggtacggg
      121 tatcattcat taattctgta tcggttggat atttgatgtt ttgtggagca caagtggcat
      181 ccaaaatcaa tgttccggaa ttgaaatcgt cataagaatc gttgtcctta tcgtcttttt
      241 tcttgtcgaa gacgagtatt ttttcattga tttctatcaa cgttgtttcg tccaagcgtt
      301 tccggaaata gaccattgta gagcatcgaa aggcttggca tcttgatagc ccggcaaacc
      361 gatgaagaac tataaatacg ggttttcttg aatttgtaag accgtttctt cgtcgctata
      421 gctatattcc ttttgaatca gtagagctcc gaaggtcatg cgaaagggtt ttgcgacgtt
      481 tccttttttt tacgaaaatt tttagcgtag tctttttcaa gttcagccca tggaatgagc
      541 tctgcttttt gaatccaacg gttagacgga ttcattttga gacctatcgg ttgattgaaa
      601 tcttcaaaag ccaattgaac ggttgtttgt aatttataca tgaaaagcct ccaaaattga
      661 gtggtactcc acaccattct gatggtgcat aagataaaaa attaaagaag tgcctgtcat
      721 ttgtctgatt taagccaagg tttgacaaat tttggatatt ccaattaata ctgtaagcgg
      781 ttatatttaa ctcagggagg tagatgaatg tgaatacaaa agatttaaaa ctgttagaaa
      841 ccattgtacg atcacatgtg acaaactctc aacaattgaa atcattagta catttttcga
      901 ctaggcagat aacttactct ataaaaaaaa ttaatgatga attatccctt catggattga
      961 gtctgataaa gcgaagtaac tcaggggagt ggttatatga agccaatgat cttcaaaaac
     1021 ttttgatata catgaatcaa gcaatggttt ttaaagaagg tgcgattcct gaatatataa
     1081 acgatgattt ggcttatagt gagataagaa gatattcgga actgttattt attctagcca
     1141 accccaaaaa agtgacaacc caagaaataa tggcgtttat tggtatcagt aaaaatacgg
     1201 ctagaaacga cttttctaaa ataaaaaaag agttgccacc agactacact ttgatatttg
     1261 atccccaaaa tggctatatg attgaatcaa gcatggcaaa gcttcataca ttgctcttag
     1321 aagttttcaa ttatttattt gaaaggcatg caacagttaa ccgttttgag tcactctttt
     1381 ctgaagaaag ggaatttgtt ggttttttta ttcacaccta cgaacaaact tttaaattga
     1441 aattttctga taattcacta accaaacttt attatttgat aggtttatca ctttctagtt
     1501 ttaaaagaag gacgaaagga cagattgatt ttagttatga tttacaggaa ttagatgagt
     1561 ttcaaatgat tcgaagctgc attgatcaac attatcaaca tgctgagata gctatagatt
     1621 atgaatggtt gacgcttctg tttttatcat tcaatacaat ttcaaatgag tttgaaattt
     1681 tagattcaag aatctatcaa gtaattatgg agatgattac cttatttcaa agtaaatcag
     1741 ctattcggat tagtaataaa gaagagttga ccaatcgatt gatgaatcat ttacgacctg
     1801 caatctatcg aattcgctac gaattaccat ttgaaataga tgatttagct gaaattgtta
     1861 aggaaaacca tgaagttagt gcggtactta attttgttaa agaatccatt gtacctttgg
     1921 aagcattttt gcgtaagacg attcctgaaa ctgaattata tttgatttct gtttattttt
     1981 gttcggagct attaaattct tctattatcg aaacacctgt tagaaaaaag gcaatcgtcg
     2041 tatgtagcaa tggattgatt atggccaatg taatggcgaa aacattgaaa gaaatttttc
     2101 cagatattca gtttgttgct agttcttcgg tcagagagat ggataagttt gtcgaagatg
     2161 ttgatttgat ttttagcaat caaccattga aaagtgaaat tccattatat attatacaac
     2221 cgattatgaa cgaagaagaa aaaaaccgct tgcggaaccg tgtactcatt gatttttcta
     2281 cgaataatat cagcaaagag actaggaacc ttactgaaat tattaagcgt tactctgctg
     2341 ttcaaaatga agaaagtcta caaactgata ttgagagatt tttaattaat tatgcaaatt
     2401 cactaatata tctagatcgt caaagtaaac aggcacaaaa gatatctttt gtggaattgc
     2461 ttgtttctga agggattatt cttgtatcta cgaaacaact tacttggcag aacgcgatgg
     2521 aattgtcttg tcagccttta ttaaaggagc aggtaattaa tcagaactat cagactattt
     2581 taatgagtca aatggcggat gaagaggctt attattttct taataatcgt attgctattc
     2641 cacattcatc gccagaaaat ggggtaatta agggcggttg ctcgttactt atatcagttg
     2701 atccaattat ttttcctgga aataggccta tccattttat ttcccctttt gcaattggaa
     2761 agaaggaaaa ttatttactt gcgattaacc aattactaca actttctaag gacgaggaat
     2821 atcagcaaga aatacttctt tgcacgacgg aagatgaagt gagaaaaaaa ataaaaaatt
     2881 ttttaaggag gaagcaatat gtcaataacg aattttcctg aattaaccat cattttaaga
     2941 ggatatagtt ttgaagaggc gatgtttgtc atggaagaat tggctgcgat gaacacttcg
     3001 gtaggaattg aagtaacaac caataatgat gactttgcac gtatcatcac agaaggcaac
     3061 aaaaaatttg ggcaacaatt attgattggt gcagggacag ttttaacatt ttcacaagca
     3121 gatcaagcaa ttgctggtgg tgcgaaattt ttattaggac caaaaaaatt ttcaacacca
     3181 attttttcgt tggctaaaga acgtggggtg gtaactgtgc catcagcttt tacgccatcg
     3241 gaaattcaag ttatgtttga tgaaggtgcc gatattgtaa aggtttttcc agcagtcact
     3301 gtagggccaa cctactttaa acaactggcc ggtccttttg gtatacggcc tttaatggca
     3361 gttggaggag tgacgattga taatattgcg gcttttaaaa aagcaggagt tgtgtacttt
     3421 ggggtaggat caagcatgtt tcaaaaagct gatatacaaa accgcaatgg gcaagctatt
     3481 cgaaaatcaa ttcaatcata tttagataaa ctagctgaag caggaagtga agaagatgag
     3541 tctcattaaa ttagaagaaa aaaatatttt gttaaatcaa agtttttcaa accaagaaga
     3601 atactttcaa aagattacaa agaaactgat gacggaaaac atggtaaagg agggatatct
     3661 cgagtcaatc actaagagag aaacaactta tccaacgggg ctatatattg gggaacgctc
     3721 aatcgcaatt ccacatacag attatcagtt atcaaatgtt accgctattt tagtatccgt
     3781 tcttaaagat agtttgcatt ttcagcgaat ggatgatccc gaagaaatgg tttcagtgaa
     3841 tgttattatt caccttttat tcgatagtcc cgataagcaa ccgcaattat tgaaggagtt
     3901 gatgagtaaa gttaccaatc aggatttctt acaagcaatt atggaagcaa agagtaaaac
     3961 agaagtttta actgcattta atcaataaat tggagggaaa tacaatgagt aaaaaaacaa
     4021 ttatcgtcgc atgtgcatca tcaatgatta catctacaat ggcagctaat aaaattcgga
     4081 aaatagcaaa aacaaatgga ttaccagaac ctcgaatttt gcaactaaaa ttttcagaag
     4141 ttgcaggtgc tttagaatca aatcaagttg actttatcgt tcctacaggg aaattacaag
     4201 aaaatgtaac caaaggaatt aaagttatac ctggaacacc atttgttact ggagtgaatg
     4261 aagaaaaatc tgaatctttg gtgttagaag cattgaaaga gcttgactag gagggtgaaa
     4321 aatgaatatt gtcattgatg cgttaaactg gatctcaagt ttgggtccga tgattatgat
     4381 gcctatcatt atcttgattt taggattatt ttttagaatt aagctaaata cattactaaa
     4441 atcagcgttg actgtgggga ttggttttgc gggtgtaaat attattatta attggtttat
     4501 ttcacaggta ggtccatctg ttcagttaat ggtcaaaaat tggggtattc aaacaagtat
     4561 tatggatgtc ggctggccag ctcgtgcagc agccacttgg tcttttcctc tagcagcagt
     4621 tatggtattt attattttgg gtattaatgt gttgatgctg atttttaaaa agaccaatac
     4681 agtaatggtc gatttctgga gttataatca ctatattttt gtagctgctt tggtttatta
     4741 tgcaacggat aaaaatatta tattggcggt aatcttcggg gcgattgatg caattattag
     4801 ttttaaactc gctgattgga caacgccgtt agtagaggat tactttgaac tagaaggggt
     4861 taatttcccg actgcgaact cagttggttg ggcacccttg gcttggctac ttaacaaatt
     4921 gtgggaccgc attcctggat taaataaggt agatgctcgt cctgaaaaaa ttcaagagcg
     4981 gtttggtttt gttggtgagc ctatgtttat gggatttgtc atcggcttgg ttattgggtt
     5041 attagcaaaa gaacctgttg ataaggtatt gatagtggga atgagtactt ctgcaacaat
     5101 ggttctaaca cctaaaatga tgcaaatttt aatggaagga ttattaccct ttgctaattc
     5161 tgttaagaaa ttcttgaatg taaaatttcc aggaaacaat tttacaatgg gtgtggatgc
     5221 tgcgttgaca gttgctaatt caagtgccat tgctacgggt attatcatgg ttccgattac
     5281 cttagtgttg gctgctattt taccaggtaa caaactctta cctatttcag atattgccta
     5341 ccaagcaatg tggctatctg catggccggt cgccttttca aaaggaaata ttattcgcgg
     5401 aatactttcc accacgatta taacagcttg tgtgctttta attgctacta gtttagccgg
     5461 catacataca caattagctt tggctggggg attccaatta ccagcaggaa tgacacaaat
     5521 atctaccgaa gatgcaggta cacacattat tggtttcatt ttaatgaaga ttgctgagtt
     5581 tatttcaaat attttctaat attcaggagg gcatacagtg aaaatttcaa aaattacagt
     5641 ctataaagta aaaccaagat ggatttttgt caaaatatct acagatgaag gtattgaagg
     5701 ctggggtgaa atgatttctg gaactaagac tgaaacagtt gtggcaggag cttatgagat
     5761 aggaaatcga ttcttagttg gtcaaaaccc atttgcaatt gaacgtctgt ttcaggaaat
     5821 gcatcgttca tttttccgag gtggtcctat taatggaacg attgtctctg gacttgaaat
     5881 ggctttatgg gatattaaag ggaaagcctt aaatgttcca gtttatgaat tactaggtgg
     5941 agcagcccgt gataaaatca aagtatattc ttggattggt ggagatcgtc cttctgaagt
     6001 agtagagcag gcacaagatc gagtagatcg tgggtttacc gccgtgaaaa tgaacgcgac
     6061 agaagaatta cactacattg attcttatga aaaagtagct gaagtagtgg aacgtgttgc
     6121 ttcaattaga gaacgttttg gagatacatt gagcattggt gtcgattttc atggtcgtgt
     6181 tcacaaacca atggctaagg ttttagcaaa agcactggaa ccctatcatc caatgttctt
     6241 agaagaagtg gttttgccgg agaatgaaga acatttcagt gaagtagcca atgcagttgc
     6301 tgtaccacta gcaacgggtg aacgtttgta tacaagatgg caatttaaat caattcttca
     6361 acagggagcg attgatatca ttcaaccaga tgtagcttta tgtggaggga ttttagaaac
     6421 aagaaaaatt gctgcaatgg ctgaagctta tgatatagca gttgcccccc atgcaccata
     6481 tggaccgatt gcgttagcag ctacattaca agttgattct tgtacaccta atgtgtttat
     6541 tcaagaacaa agcttaggta ttcattacaa caaagggttt gatttgttag attttgtaaa
     6601 gaataaagag atattccaat acaaagatgg cttcgtagat cttccgacaa aaccaggttt
     6661 agggttagaa atggacgaag atcgagtgaa agaaattgca caagaaggtt tagtttggac
     6721 caatcctaag tggaaaaatt atgatggtac aatcgctgaa tggtaggaga tgagtgcatg
     6781 atcaatacgg ttacaggccc aatcgaagct gagtctttgg gtacaacatt tattcatgaa
     6841 catttatatg tcattcctaa tgagttaaga aagtatgaag attatacctt ggatgatatt
     6901 tatcatagta ttgcggaagt tatggctttt aaacaagctg gtggaaaaac tatcgttgat
     6961 ttgacaccaa ttaattatgg acgaaatccg ttagctttga aaatgatatc tgaagctacc
     7021 ggagtgaatg tagcatttgt tacgggattc cataaggaag agtttcagcc aaaatggttg
     7081 acaacgctca atgatgatga gatctttgag ttgctttatt ccgaaataac tcacggagtc
     7141 acttcacaaa accttttgcc aggagcaatg aaagtaggta cgagtaaaaa tgaggttaca
     7201 ttggctgaac aacgaatact agccatagcc ggtcaagtac aaaaaaaaac agggattccc
     7261 attattacgc attgtgatgg ggggacgatg ggactggagc aaattaattg tttaacaaaa
     7321 aacggtgcga aagcaagtaa tatttgtttg agtcatgtag atttaactaa agattttcac
     7381 tatttagctc aaatctgtga aacgggagca agtatttgta tggatcatat tggccgagag
     7441 ttggcgaatc atgatgcaga ccgcgtccaa ctaattaaac gactggttga tgcgggttat
     7501 gaaaatcaga tttgtctttc aggtgatatg ggacgaaaaa aatatttgcc aacttatgga
     7561 ggaacgcctg ggcttaccta tattttaaca agtttgaaag aagaactatt aaaagtaatg
     7621 agtgaaccaa cttttaataa aatgattgag atgaatccaa ttaatatact gagtaagtga
     7681 agtcaattga atcattcaga agaactaatg aaattagttg ctttcgcagg gttaattctt
     7741 ctctctgggt ttggaaaaga gggcttagct tcggattccc tagttaaact aggggtttta
     7801 tcaggttatt gtactgatta taagtacctg aattattcat gaaatacttt ttccgtcgtt
     7861 ttataggcag ttgggtcaat aaaaagatca gaaaaacgaa cgagagactc tcataacgtg
     7921 ccactaaata aaaatcgtac gttattttaa aaaatgggtt gattctaggc agtactttgt
     7981 cggtctattt ttagaaaaag aggttctttg tcaaacatac atgaattcgc aagctcattc
     8041 accctgaagg atgaaaggca gaaactgtag tatactaatg gtggaaagga aaaaaagccg
     8101 ccagcaattt ggaaaagaac gttatgtcga ttgtcaaact ggcttgcttt atttctcgag
     8161 aaccctgaaa tatagccaat gagcatgtgt ataaaaaatt gattttatat gaaataaagc
     8221 actcctttcc taaaattatt ggaaaggagt gcgtttttta tggaaattat ttaggttctt
     8281 tgtcaattgc tattgttttg ctcaaatcgt atgttaggaa atgcttcggc atttcctttc
     8341 cttttttgcg ttattaaatg atttcacaga tgttctgttg aatcaggaca cgcatccgga
     8401 gatgacgaaa agtccgaaat ccaaaagcaa ttcttttgat tactttgatg aggttattct
     8461 ttccctccaa ttttccgttt gaatagggat attttaagga gtttgtgatt gcttctgtgt
     8521 gctttttcag ataacaaatt gcctttttaa acccatcatt caaggaatgt ggcaatgatt
     8581 caatgagatt gaaaaattca gtaaaatctt ttgcatcaaa agcagctaat aactcttgat
     8641 agacttcata gctttgtcgt agttggttat ctatagagag taggtaatca a
//
LOCUS       DAPBCF010000084         8608 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.086, whole genome shotgun sequence.
ACCESSION   DAPBCF010000084 DAPBCF010000000
VERSION     DAPBCF010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8608
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.086"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            197..1489
                     /locus_tag="RD508_002624"
     CDS             197..1489
                     /locus_tag="RD508_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDT7737149.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSECRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
     gene            complement(1701..2543)
                     /locus_tag="RD508_002625"
     CDS             complement(1701..2543)
                     /locus_tag="RD508_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7737150.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
     gene            complement(2580..4046)
                     /locus_tag="RD508_002626"
     CDS             complement(2580..4046)
                     /locus_tag="RD508_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7737151.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            complement(4102..5946)
                     /locus_tag="RD508_002627"
     CDS             complement(4102..5946)
                     /locus_tag="RD508_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7737152.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            6548..7500
                     /locus_tag="RD508_002628"
                     /pseudo
     CDS             6548..7500
                     /locus_tag="RD508_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300609.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            complement(7545..8178)
                     /locus_tag="RD508_002629"
                     /pseudo
     CDS             complement(7545..8178)
                     /locus_tag="RD508_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(8438..>8608)
                     /locus_tag="RD508_002630"
     CDS             complement(8438..>8608)
                     /locus_tag="RD508_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737153.1"
                     /translation="QDLFNDVVKELDLFREKYPIVPELDDRGEIIRTTSQIKQDTEDS
                     LRKGWGMNNKVR"
BASE COUNT         2643 a         1748 c         1407 g         2810 t
ORIGIN      
        1 gttttagtga cgataatatg aattttaaga ccataaaaat aagcgttttt cgttgagtta
       61 tagcccctac agctctatac tttttgatgt tggtggatga caccagcatc ttttttattt
      121 tccaaaacat atagaaaaga caccttgaaa tcctttagaa ttaatttggc gaaccaaccc
      181 aaaaggagga atcaagatgt cttacactca ccttatcaaa gaaacattag atattctaga
      241 cttatcagtt acttttaacg aaaattgtct cacaaaagaa aaatacaaag ggcaaatctg
      301 tcatatttat cgtggaaact tgatttatac agcccaagaa tgcatccact gtaaacacca
      361 gattgcttca gatattgtgc gttggggtac aacaaccgtc cggttgttaa tgaacgatgt
      421 ttctgaatgc cgtacctacc tcgaattgaa aaagcaacgc ttcaaatgca aagcttgtca
      481 gcggaccttt gtcgcagata cttctgttgc gaaaaaacac tgtttcatca gtgagaaagt
      541 ccgctggtct gtcgtgactc gtctgaaaaa aaatacctca atgacagaga tcgccgctca
      601 gaaaaatcta tcggtctctt ctgtttaccg tattatgaag cgattttatc gtccgttgaa
      661 tccttttcgg acaccgttac ctaaggtact ttgttttgat gaattcaaat cagttcgggg
      721 tgtttcaggt gctatgagtt tcatcatgat ggatggacaa acacagcgct tgttggacat
      781 tgtcgagaac cgacaactgc cttttttaaa acgttatttt agtcattttt cacgagaaat
      841 tcgtgaagcg gtcgaatgga tcgtgattga tatgtacgct ccttatgtat cgctcgttaa
      901 aaagctgttt ccaaaagcac agctgattat tgaccggttt cacatcgtcc aacatattgg
      961 tcgtaccttt cgcaatcatc gaatcaaaga aacgaaccaa ctattaaaaa gcaaagaaca
     1021 aaaacactat caattaggta agcaattaaa aagatactgg aaacttcttc aaaaagatga
     1081 acgcaagctt gattatactc gacgcctttg gcgacctggc ttcaaagctc atttaacaga
     1141 gaccgatatt gtggatcgct tactgaaagg gagccctgct ttgcgtgtag gctatcagtt
     1201 atatcaagac tttctttacg ctgtaaagga acgagactac gtatcgtttg aagaactact
     1261 taccaataat atcatgcttc ccgaaggcta tcagacgacc ttgagaacgt tccagaaatt
     1321 tctgccacaa atcaaaaatg ctttacaaca aagttattca aatggcccac ttgaatgtct
     1381 gaacaaccat atcaaagtgt taaaacgaaa tgcatatggc tttcgtagct tttataattt
     1441 caaattgcgc atcatgattc gtcatggcaa cgcattgatt ttcaactaaa aaagatcaag
     1501 aggaactgat ccacttgatc tccaattatt ctaagatttc tctttaccaa catcatttga
     1561 caaagagccg agatttttta ttatcttacg ttaatccttt ttaaatgtct cttatagata
     1621 acaaacagct ggaaatcacc ttgtttttac tataatccat ctctaaagat tttaaaagca
     1681 tcaatagtat tactgagcgc tcacccatta gcatgtttca tcaaccgatt gatgtggaca
     1741 cctaggtata caacttcatc gttcggaatt gttttatgat aaactttttc aatgtagtct
     1801 ttgatcttag ctgcgctttc catggcagac gggtataaga tccacatttg attgtagaat
     1861 tcttcctcac catcatccaa caaagcatca gaataatatc tttctacaaa gaaacgtaca
     1921 tgtgtaatga agcgggcata atggatcgaa ttagtatcga tatctttctg caacgaatac
     1981 cggaccaaat tgacgatccc gccgatcatt tttgcatact tgaatccagc gccgctatca
     2041 ggatcttccg attgtgcatt gatcaaatgg aaagcaatgt ttgaggcttc ctctttagga
     2101 agatcaattc catattgctc gttcaaaagg gtgagtgcgt acttcccaat ttgaaattct
     2161 ttgggatagt agatttttat ttcccagtac aaacggtttg caatatttac ccctttttgt
     2221 gcgcgttcaa ctgcaaaatg caggtggtct gttaaggtta aatagactcc aggattcagt
     2281 tttttatcta atcctttttc tgcttcaaaa acgatagtac gagtgatttc aaaaaattca
     2341 ataggtattt cttcaactaa ctctaatagt tgtgaagatt tcttttcttc aaaaggcaga
     2401 aatattttat ctactttatc tcctgatatt tcatccccag ctttctgtcc aaagcctatc
     2461 cctttaccta atgcaatcat ttctttgcca ttttcttcaa ccagtaccac acttgaattc
     2521 aatacttttt ttattgaaat cactcattat ccccctatcg ctgcttaaaa agatcgagac
     2581 tactcgaata aggatgcacc gtttgtttcg atcacttctt tgtaccagtt gaacgaatcc
     2641 tttttcaagc ggttatatgt cccatttcct tcatcgtctg catccacata aataaatcca
     2701 tatcgtttag acatttgaga agttcctgca ctaactaaat caattggtcc ccagctagta
     2761 taagctatca aatctacacc ttcatcgatt gcttctttca tttgttggaa gtgtgcttta
     2821 aagtagtcga tgcggtacgg atcatggatt ttaccatcta ctacctgatc gactgctccc
     2881 ataccatttt ccacaatcat caacggtact tggtaacgat cataaagttc gatcaacgaa
     2941 attttcaaac cttttggatc gatttgccag ccccaatctg ttgaaggcaa atgaggattc
     3001 ttaaccccta aaacagtatt tcccggtgtg cgttctgcgt ttggatcagc tgattctgcc
     3061 atggacatgt aatagctgaa agaaacaaaa tctacggtat gtttctttaa aatttctcga
     3121 tcttcatctt ccattttaat ctgaattccc cgattttcca aatccttttc gattagagca
     3181 ggatattctc ccttaacttg aacatctgca taaaaattat tttctaagtt ctttttcaag
     3241 gtcagctcaa cgtcttctgg tgcgcaagtt aatggataag tcatcaattt cgttaacata
     3301 caaccaactt ggcttcctgg aattttttca tgagcatctt ttgtcactaa cgcactcgca
     3361 acaaattgat gatgcaatgc ttgatagata tcttgagctt cttgaccttc tgcgcttttc
     3421 tcttggataa ttccagctgt tgtaaatgga tgacggtgga tgctgtctat ctcattaaat
     3481 gtcagccaat attttacgta tttgccgaag cgatcaaaac aaacgttagc gaagcgaaca
     3541 aaatcatcaa ttactcgacg ctccacccag ccattatatt taactgctaa agctaatggc
     3601 atttcataat gagatagtgt cacaatcggc tcaattccta aacgttgcat ttctttaaag
     3661 acgttttcat aaaatgcaac ccctttttca ttcggttcca gctcttctcc tgtagggaac
     3721 aagcgagtcc aagcaataga gaggcgcaag gttttaaagc ccatttcggc aaataaagct
     3781 aaatcttctt tatagtgatg ataaaaatca acgccccttc tttttgggta ccatttatca
     3841 gatttgtctt cactagcttc ttttatagac tgcagggtga catgcatatg agcagcaaaa
     3901 tctttgttgt ctaaatttgg tttataagta gccatatccg ctactgaaag acctttaccg
     3961 tctacattcc aagcaccttc tacttgattt gctgctatcg cgccgcccca taaaaatcct
     4021 tttggaaaac ttgttgtgtt tgtcattatt ctattctcct ctattccttc attcaatata
     4081 ttttttttca ctatcttgtg tttaagctat cggactgata gctaagagat cactatcatt
     4141 ggttaccaat ttttctaggt taaatgaacg gatagtgtaa ttatccttat tggttaccac
     4201 acagataact gtggggtcga atcctgcttc tttgattaaa tcaatatcaa atgcaatcag
     4261 cttttgtcct ttggctactt tttcaccaga acgaacaaat gcctcaaacc cttttccttc
     4321 taactgaaca gtatcaatac caatatgaaa aagaagttct gcaccattag ccgtttttaa
     4381 accaatagca tgcttcgttt caaataccat tgtgatttct ccatcttcag gagctactaa
     4441 tatcccttct tcaggaatga ttgctactcc atcacctacc ataccactag aaaaaacagt
     4501 gtcttttact tctgatagtg agattacttt tccattcacg ggacttgaaa gaacagcatc
     4561 tgaaacaacg gccgtttcca tcttagtttc aacttcattg acaacttctt tatctttata
     4621 aagaaccaac gctgcagcaa aagcaaccac aaatgaaatc cccgatactg caaatgccca
     4681 aaccagattc attgggtcag ctttgtcagc gaacatcgtg atacttgcaa tcccaggacc
     4741 cactaaagca aaggcttgaa gtgcaacgat tcctgcaaat gctcccccga tcaggctaga
     4801 aaacataacg gcatataaaa cacgtttgtg cagaatcgtt accccgtaaa gagctggttc
     4861 agtaattccg aataatgcag atatacccgc agaaacagcc gtagatttca attttttgtc
     4921 ttttgttttg atactgacag caaagcatgc gccagcttct gaaatattgt gtgccaatga
     4981 agccgggaga taaagaagtt ctgcacccaa ttcactcatg gatgaaacag cgtaagggat
     5041 cattgcttta tgcatacccg ttacaaccat taatggcagt acagctgcta agactccggt
     5101 tgcaacccat ccaaattgat tgtacaaaga cacaatgata gaagagaaag ctgttcctac
     5161 attataacct aatggtccta gaagcaacaa agcaatagga actgtaatca ataagctcat
     5221 cataggtaca aagaaaatac gaattggttt tggtgaaact tttgtaaacc atttttcaag
     5281 ttgagcataa aataaaacag ttaagatggc tgggaatact tgagatgcat acgctatatt
     5341 atccaatcca aaagataaga atgtagcacc ttccgccaac atagctgtca tttcaggaag
     5401 gatcaatgca ccgacagcag atactgcaac caattgattg actttcaatt tattagccgt
     5461 agtcattgcc accagaatag gcaagaaata aagcggtgcc ccgccgacca aatttaaaat
     5521 ctgataggtt tgagattggt cactaatcag ccctaagata gaagctagta gcaacaagga
     5581 cttcaatact cctccacctg caatcgcagg aattaaaggt tggaaaatag aaataataaa
     5641 atctaataga actgaaccta atttttgttt ttgttttggt gcttcttcag tatttgaaac
     5701 attgtcacct aataacgctt tcacttcatc atacacttca acaacatcgt ttccaatgat
     5761 tacttggcat tgcacatttt ggcgaacgcc cataacgcca tccacttttt ctaactggct
     5821 catatttacc ttgctgttgt cttttaacgt aaaacgtaaa cgagttgagc aatgctccaa
     5881 atgggatatg ttttcttccc caccgatgta ctgcaatact tcttctgctg tttgtttgta
     5941 attcatggtg tttccctctt ttcttttttg agtgatgaac ttttgagtcg aagtggccat
     6001 cctcaacaca aaaaacaggc agaaactaaa taaattgaca acaaggcaaa cgtgtattga
     6061 aacgcataca ttgttattca acttatttag gtcctgcctg cattaccagt cacatgcctg
     6121 tttaagttat attcaattta acatattaga atgtaaacgt aaataataaa atgatttttt
     6181 aatcattttt tcattttatt cgttcaatat agttttcgtg ttctaaaagt tttgtctttt
     6241 ttctaagaat atcttccaac atatataact cttattctct tctatcttct agcagatgtt
     6301 ctgtcttttt aagacctagt ataaaaagaa tgggttcatt ttttctttct tgcaggatga
     6361 ggttttttat ataaacttta tttgatataa agaaaaggca ttcataattg tgctatacta
     6421 ctaaaaaatg ataatacagt gaattagatt agcgctttat taaattaaga ggacagcata
     6481 tcgatattgc ttcctttttt ttgctattta tttaagggat agaagtttag aaaggactgt
     6541 ttataagatg aaaaatgata tagtgactta tgcaaacaca aaatgtgaag aaattggcat
     6601 cagtaattta gaagagtgct tttttgacac aaatgacctg tcgcaatttt taagaacggg
     6661 aagaacaaat gccagtaaac ttgccaatga cttagttgca aagaacgttc tatttaaaat
     6721 caatactcgt ccagtgttat ttgccatcaa agagcgcttt gaagagcact ttttgattcc
     6781 ggtaaaagat gtatacgaaa gtatatctga attaaaaaca gacttggagc ccaattctac
     6841 agattccatt ctacaaaaga tgattgggta tgatatgagc ttatccgatg cggtggaaca
     6901 aatgaaaact gctgtcttct atcctggaag agggcttcct atgatgatca ctggagatac
     6961 tggagttgga aaaagttttt ttgttcatac tgcttatcag tttatgaaaa aagtgaacgt
     7021 tattcatgag aatgctcctt ttaaagtact taattgtgcg caataccata ataatcctga
     7081 attattgtcg gggatactat ttggctatgt taaaggtgct tttaccggcg cagatgaaga
     7141 tcgaaatgga ttgttgcaag atgcagacgg tggagtactg tttttagacg aagtacacag
     7201 attgcctcct gaagggcaag agaaactatt tgtttatatg gagatggcgg aacttattct
     7261 agagtcggtg aaactatcca tcacgcctcc aatgtacgtt tagtttttgc gactacagaa
     7321 ggcaaagagg attttctgga aacctttatg cgaagaatcc ctatacatat ccatatccca
     7381 aatattgagg aacgaggtat tttagaaaaa aaacaaatta tcgaaaatac tctctttagc
     7441 gaaagcaaaa actttagcaa ggctattgat gtttctccta aagtcactag tgttgcataa
     7501 atatagtcag aatattctga attattattt tcttgaaaaa agtaaaaaaa atcgtatccc
     7561 aaactttcat ctacatttcc agaaagatct tcatgttgat aatcaattcc tgaatcaatg
     7621 accgctacct tcacatcctt agaacccttg gtttcttccc aagcggatgg catgctaatc
     7681 tctcttaaat tagcttgttt actccaatta ggatcgttat cgatttccta aagaatcagt
     7741 tgtatttggc tcctcaacat cattcaacgg ctctagttca accacatagt ttggctctgc
     7801 ataattgacc atatcagaag cattaaatgt tcttactgcc tcttccacac taatttcttc
     7861 gttcaatttc actaataata cttgatctcg cttattataa tcgctttcat ttgtcctaag
     7921 agtcaaatct ttttccacca taacttttac acccaataaa ttttgcggtt tatttttctc
     7981 tgttgaaatt ctttgtgtag cctttaaact gacaattagc tcattgggta catactctat
     8041 ttgagagtca tctaattggc tcataatcct ttctttttgg ttagtatctg cagttacttg
     8101 tttagtatga gccatgaacc caaacatact taccccaaca accaatccta aatatatttt
     8161 ctttttaaac tttttcatct acatctcctc ctaatagttt tattttagag ttagctctat
     8221 tacttattta ctaactcaac aacagattat catacacttg ttaatgaaat cacaatatct
     8281 cattaaaaca caccctaaaa tcataaccgt tcctatgctc attttttgga ttttttaatc
     8341 acgtaaccag aaaaataaat cccctctatt tcacgcaaat caaagaagaa ctaagtaact
     8401 accgtttaaa ggtagttact tagttcttct ttgattatta tctaacttta ttattcattc
     8461 cccacccttt gcgcagtgag tcttcggtat cttgttttat ctgactggta gttcttatta
     8521 tttctccacg atcatctaat tctggaacaa ttggatattt ttctctgaac aagtctagtt
     8581 ctttcaccac gtcattaaac aaatcttg
//
LOCUS       DAPBCF010000085         8251 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.087, whole genome shotgun sequence.
ACCESSION   DAPBCF010000085 DAPBCF010000000
VERSION     DAPBCF010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8251
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.087"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..197
                     /locus_tag="RD508_002631"
     CDS             <1..197
                     /locus_tag="RD508_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737154.1"
                     /translation="WFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLIIAIIAVGLV
                     FNAAGVKDILLELFNRIIGA"
     gene            314..811
                     /locus_tag="RD508_002632"
     CDS             314..811
                     /locus_tag="RD508_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDT7737155.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            898..1290
                     /locus_tag="RD508_002633"
     CDS             898..1290
                     /locus_tag="RD508_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7737156.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            1274..3721
                     /locus_tag="RD508_002634"
     CDS             1274..3721
                     /locus_tag="RD508_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7737157.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSDGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            3724..5907
                     /locus_tag="RD508_002635"
     CDS             3724..5907
                     /locus_tag="RD508_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDT7737158.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGERIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            5904..6905
                     /locus_tag="RD508_002636"
     CDS             5904..6905
                     /locus_tag="RD508_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDT7737159.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            6920..7834
                     /locus_tag="RD508_002637"
     CDS             6920..7834
                     /locus_tag="RD508_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7737160.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            8079..8195
                     /locus_tag="RD508_002638"
     CDS             8079..8195
                     /locus_tag="RD508_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HDT7737161.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
BASE COUNT         2568 a         1568 c         1755 g         2360 t
ORIGIN      
        1 actggtttct atcaaacgct caatcactgg tgcttttagc aatcgttgtg attggcttgt
       61 atcttggctt caagcgtgag tttagcaaac tgattggctt tttaattatt gcgattattg
      121 cggttggctt agtcttcaac gctgctggag taaaagacat tttactagag ctattcaatc
      181 gcattattgg tgcttaaata aaaccgttct tttgtggaat ataagtggtt ttcttatgtt
      241 ccgcaaagga atggtacacc aaacgaagtg cggtagggat ttttgaatct ctacaaagaa
      301 aggacgtgaa tatatggacg atatgcaagt ctatattgcg aatttaggca aatacaatga
      361 gggcgaattg gtcggtgcgt ggtttacctt tcccattgac tttgaggaag tcaaagagaa
      421 aatcggcttg aatgatgaat atgaggaata cgccattcat gattacgagt taccctttac
      481 ggttgacgaa tacacttcta ttagcgaact caatcgccta tgggaaatgg tatcggagtt
      541 gccagaagaa ctacaatcgg agctatctgc tctgctcact catttttcaa gtattgaaga
      601 actaagcgaa catcaagaag atattatcat tcattccgat tgtgatgata tgtctgacgt
      661 ggcacgctac tacattgaag aaacgggtgc tttaggcgaa gtgccagcca gtcttcaaaa
      721 ctatattgat tatgaatcct atggtcggga tttagacctt tcgggaacgt ttatctcaac
      781 caatcacggg atttttgaaa tcgtctatta aatctgtcgg tacattctta ctggcagatt
      841 ttcttgttta cggggtagtc aaaagactat ccccattttt atgaaaggat tgattacatg
      901 aagaaaatac gaagctatac cagtatctgg tctgttgaga aagtgttgta ctccatcaat
      961 gactttagac ttccgtttcc cataaccttt acgcaaatga catggtttgt cgtgtcactc
     1021 tttgcagtta tgatacttgg caacttgccc cctctttcta tgatagaggg agcatttctc
     1081 aaatactttg ggattcctgt ggctttcaca tggtttatgt ctacaaaaac ctttgatggt
     1141 aaaaagcctt atggattttt gaagtctgtc attgcttatg cactgcgacg aaagctgacc
     1201 tatgcaggaa aaaaagtaac gcttggcaga aaccagccac aagaagccat tacagcagtt
     1261 aggagtgaat tttatggcat atccaattaa atatattgaa aacaatctgg tctggaataa
     1321 agatggggaa tgttacgctt actatgagct tgttccctac aattactcat ttctaagtcc
     1381 ggaacagaaa atacaagtac atgattcttt cagacagctt atcgcacaaa atcgtgatgg
     1441 caagattcat gctttacaaa tcagtacaga atccagcata ctttctgcac aagaacgttc
     1501 caaaaatgaa gtcactggaa agctcaaaac ggttgcctat gacaaaatcg accaacagac
     1561 agacgcttta atatccatga ttggcgaaaa tcaagtggac taccgtttct ttatcggttt
     1621 taagttgctt ctcaacgatc aggagttttc tatgaaaagt cttaccgttg aagcaaaaaa
     1681 tgcttttact gattttgtct atgatgtgaa ccataagctg atgggcgatt ttgttagtat
     1741 gagtaatgat gaaatcctgc gttttcagaa gatggaaaag cttttagaaa ataaaatctc
     1801 ccgtcgtttc aaaatccgaa gattagataa ggatgacttc ggctatctga ttgaacacct
     1861 ttacggacag acaggcactg cctatgaaga gtatgagtat cctctatcaa agaaaaagct
     1921 ggaacatgaa acactgatta aaacctatga cctcattaag cctactcgct gtctggtgga
     1981 agaaaaacag cgatatttga aaatccagca ggaagacgaa accgcctatg tagcttactt
     2041 taccatcaac agtattgtcg gcgaactgga cttcccgtcc tctgaaatct tctactacca
     2101 gcaacagcaa tttacctttc cgattgatac gtcaatgaat gtggaaattg tagcgaatcg
     2161 taaagcccta tctactgtcc gcaataaaaa gaaagaactg aaagacttgg ataaccacgc
     2221 ttggcaaagt gataatgaaa ccagctctaa tgtggcggaa gctctggaaa gtgtgaacga
     2281 gctggaaacc aatttagacc aaagcaagga atctatgtat aagctgtcct atgttgtaag
     2341 ggtatcagca aatgaccttg acgaacttaa acgtcgttgt aatgaagtga aagatttcta
     2401 tgatgatttg agcgtgaaac tggtacgacc ttttggggat atgctgggct tacatgaaga
     2461 atttttacct gccagcaaaa gatatatgaa tgactatatt caatacgtga cctctgattt
     2521 cctcgctggt ttaggttttg gtgctactca aatgctgggt gaaaatgagg ggatttatgt
     2581 tggctacagc ttagatactg gacgcaatgt ctatctgaaa cctgctcttg ccagtcaagg
     2641 ggttaagggt tcagtaacca atgcgttagc gtctgccttt gtcggttcgc tgggtggtgg
     2701 taaatccttt gcgaataacc ttatcgtcta ttatgcagtg ctttatgggg cacaagcagt
     2761 gattgtagac ccaaaagcag aacgtggcag atggaaagaa accttgccag agatttccca
     2821 tgaaatcaat atcgtcaatc tgacttctga tgagaaaaac aaaggcttac ttgaccctta
     2881 tgtaattatg aaaaatacca aagattctga atcactggct attgatattt tgacattcct
     2941 tacggggatt tcctctcgtg atggggaacg cttcccaatc cttagaaaag ccattcgtgc
     3001 agtaaccaat agtgaagtgc gagggttgat gaaagtgatt gaagaattac gggttgagaa
     3061 tacgccacta agtaccagca tagccgacca tatcgaaagt tttacagact atgactttgc
     3121 ccatctgctt tttagtgatg gttatgtaga gcagtctatc agccttgaaa aacaactgaa
     3181 cattatacag gttgccgact tggtacttcc tgacaaggaa acttcctttg aggaatatac
     3241 cacaatggag ttactatcgg tagcaatgct gattgtcatt agtacctttg cgttggactt
     3301 tatccataca gaccgaagta ttttcaagat tgtagactta gacgaagcat ggagcttctt
     3361 acaggtggca caagggaaaa cactatctat gaagctggtt cgtgctggtc gtgctatgaa
     3421 cgctggggta tatttcgtga cccaaaatac agatgacctc ttagatgaaa aactgaaaaa
     3481 taacctcggc ttaaaatttg cctttcgttc cactgacctt aacgagatta aaaaaaccct
     3541 tgcctttttt ggtgtagacc cagaggacga aaacaatcag aagcgattgc gtgatttgga
     3601 aaacgggcaa tgccttatca gtgatttata tggtcgtgtc ggtgtgatac agttccaccc
     3661 tgtatttgaa gaactgctcc atgcctttga taccagacca cctgtgcgaa aagaggtgta
     3721 aatgtgaaac catcaatatt aaacagaata aaatcaaact ggacgctgaa acgtctaggt
     3781 aaagtggcaa tgacagtggc tttcacactt gtgattgcca tttttctttt agccatgctg
     3841 ggaacggtgg ttcaagctgc gggcttggta gatgatacgg tcaatgtggc aaatgaatac
     3901 agccgatacc cacttgaaaa ctatcaactg gatttttatg tggataatag ctggggctgg
     3961 ctaccgtgga actggtcgga cggaattgga aaacaagtca tgtatggact atatgccatt
     4021 accaatttta tttggacaat cagtctttat gtttccaatg cgacgggtta cttagtacag
     4081 gaagcctatt ccttagactt catttccgct acagcagatt ccattggcaa gaatatgcag
     4141 acccttgcag gggttacgcc tagtggacta tcaacagagg gtttctatgt tggattcctt
     4201 ttactcttga ttttggttct tggggtttat gttgcctata caggactgat aaagagagaa
     4261 accacaaagg caattcatgc cctcatgaat tttgtgctgg tttttatcct atcggcttcc
     4321 tttattgcct acgctcccga ctacattaaa aaaatcaatg acttttcatc agacatcagc
     4381 aacgctagtt tgtcactggg tacaaaaatt gtcatgcccc attcagatag tcaaggcaag
     4441 gacagtgtgg acttgatacg tgacagccta ttttccatac aggttcagca accgtggcta
     4501 ctgcttcaat ataacagttc agacattgaa agtattggta ttgaccgtgt ggaaagcctg
     4561 ctctcaacca gtccagattc caacaatggg gaagacagag aaaaaattgt tgcggaagaa
     4621 attgaagata gaagcaatac caatatgacg attacaaaga cgattaaccg tttaggtaca
     4681 gtcttcttcc tatttgtctt caatattggg atttccatat ttgtattcct attaacagga
     4741 atcatgattt tctcgcaggt actttttatc atctatgcta tgtttctgcc tgtgagcttt
     4801 attttaagca tgattccatc atttgatggt atgtcaaaac gagccataac aaagctcttt
     4861 aataccattt tgacacgagc tggaatcaca ttgattatta cgacagcatt tagtatttca
     4921 accatgctct ataccttatc ggctggttat ccgttctttt tgattgcttt tctacagatt
     4981 gtgacctttg caggaatcta ctttaagctg ggcgatttaa tgagtatgtt ttctctacag
     5041 agtaacgatt ctcaaagtgt gggaagtcgt atgatgagaa aacctcgtat gcttatgcac
     5101 gctcacatgc accgtctaca gcggaaactt ggacgctccg tgactgcttt aggggctggg
     5161 tctgccattg ccagtgctac gggtaaaaaa ggacagtcgg gttcgggaag ttctgcgagt
     5221 acacaagcag atcactctcg accaaacggg caggaaaaat caacactagg agagcgtatc
     5281 ggtcaaacca tcggtacagt agctgatacc aaagacagaa tggtagatac tgctggtaat
     5341 ttgaaagaac aggttaagga tttgccgacc aatgcaagat atgcagtata tcaaggaaaa
     5401 tctaaagtga cggataatgt ccatgattta accagaagta tttctcaaac caaagcggat
     5461 aaagccagtg gacgcaagaa acagcaggaa caaagacgga aaaccattgc ggagcgtcgc
     5521 tctgaaatgg aacaggtcaa acagaaaaaa cagccagctt cttccgttca tgaaagacca
     5581 gccactaagc aagaacaatc tcatgatgga cagacttcaa ggcaaacaac tgtacaggct
     5641 tcctataggg aatctcaaca agccaaacaa gagcgtccaa cagttaagtc cgattcttca
     5701 agtttaaaaa cggaacgtca aagtaataca gttcaagaaa gaacggttca aaagccagta
     5761 acttcaactg caccaacaga tagagcttca caacgttcaa tcacaaaaga acgtcagtct
     5821 actgttcaaa gagtaccact acaaaataca aaaagtagac caccaatcaa aaccgccacc
     5881 attaagaaag gcagtaagaa accatgaagc tgaaaacttt agtgattggt ggttcgggat
     5941 tattcttgat ggtcttctca ctgcttctgt ttgtcgccat tttattttca gatgaacaag
     6001 atggcggttt ttccaacatt cactatggcg gtgtggatgt ttccgcagaa gtgctggctc
     6061 ataagcctat ggtagaaaaa gttgccaaag aatatggaat tgaagaatac gtcaatatac
     6121 ttcttgcgat tatacaggtg gaatcgggtg gtacagcaga agatgttatg cagtcctcgg
     6181 aatccctcgg tcttccacct aattcattga gtacagaaga atccattaag caaggtgtga
     6241 agtatttcag tgagttatta gccagtagcg aaaggcttgg tgtagattta gaatcggtta
     6301 tccagtccta caattatggt ggtggtttct taggatatgt ggctaatcgt gggaataaat
     6361 atacctttga actggctcaa agtttctcaa aagagtattc gggtgacgaa aaagtgtctt
     6421 accccaatcc catagccata cctatcaatg ggggctggcg atacaattac gggaatatgt
     6481 tttatgtgca actggtaacg cagtatcttg tcacaacaga gtttgatgat gatacagtac
     6541 aagccatcat ggacgaagct ctgaaatttg aaggctggaa gtatgtctat ggcggagctt
     6601 ccccgactac ctcttttgat tgtagcggac tgacacaatg gacgtatgga aaagctggaa
     6661 tcaacttacc acgaacagca caacagcaat atgatgtaac ccggcatatc ccattattgg
     6721 aagcaaaagc cggcgatttg gttttctttc attctaccta taacgctggc tcttatatta
     6781 ctcatatcgg gatttattta ggcgataacc gtatgtttca tgcaggcgac cctatcggtt
     6841 atgccgactt aacaagctct tactggcaac agcatttagt gggagcagga cgaatcaaac
     6901 aataagaaag gacgattcaa tgatgaaatt cggaaaaaat cagaatacag aaaaacagac
     6961 accaaaggaa aagaaacctc gtgtctataa ggtcaatcct cgtaaaaagg ttgtgattgt
     7021 cctatgggta cttttaggac ttagtttcag ctttgcgata ttcaagcact ttacagccat
     7081 tgatacccat accattcatg aaaccaccat catagaaaag gaatatgtcg atactcatca
     7141 tgtggaaaat tttgtagaga actttgcgaa agtctactat tcatgggaac taaacgacaa
     7201 gtccattgat aatcgcatag aaaacctgaa agcatatctg acagaggaac ttcaagctct
     7261 gaatgtcgat acagttcgta aagatattcc tgtatcgtct tctgtaaaag gatttcagat
     7321 atggacggta gaagcagatg gcgacaatca atttgatgta acctacagtg tagaccaact
     7381 cattacagag ggggaaaata caaagaccgt ccactctgct tatatagtga gtgtctatgt
     7441 agacagtact ggaaatatgg tcctcattaa gaatccgacc attactagca taccaaagaa
     7501 atcagactat aaaccaaaag ctattgaaag tgagggtacg gttgattcca ttacaaccaa
     7561 tgaaatcaat gagtttttaa cgacgttctt caagctctat cctacagcga cagccagtga
     7621 actttcctac tatgtgaatg acgggatatt aaaaccaatc ggaaaagagt acatctttca
     7681 agaactggta aatcctattt acaatcgtaa ggataatcaa gtcacggtat cgctgacagt
     7741 ggagtatatc gaccagcaga ccaaagcaac gcaggtatct caatttgatt tggtacttga
     7801 aaagaacggg agtaattgga agattataga ataacaaata ttggtacatt attacagcta
     7861 ttttgtaatc acgtactctc tttgataaaa aattggagat tcctttacaa atatgctctt
     7921 acgtgctatt atttaagtat ctatttaaaa ggagttaata aatatgcggc aaggtattct
     7981 taaataaact gtcaatttga tagtgggaac aaataattgg atgtcctttt ttaggagggc
     8041 ttagtttttt gcacccagtt taagaatacc tttatcatgt gattctaaag tatccggaga
     8101 atatctgtat gctttgtatg cctatggtta tgcataaaaa tcccagtgat aagagtattt
     8161 atcactggga tttttatgcc cttttgggct tttgaatgga ggaaaatcac atgaaaatta
     8221 ttaatattgg agttttagct catgttgatg c
//
LOCUS       DAPBCF010000086         8066 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.088, whole genome shotgun sequence.
ACCESSION   DAPBCF010000086 DAPBCF010000000
VERSION     DAPBCF010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.088"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..883
                     /locus_tag="RD508_002639"
     CDS             <1..883
                     /locus_tag="RD508_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HDT7737162.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            931..3060
                     /locus_tag="RD508_002640"
     CDS             931..3060
                     /locus_tag="RD508_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HDT7737163.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3035..3724
                     /locus_tag="RD508_002641"
     CDS             3035..3724
                     /locus_tag="RD508_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737164.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(4132..4818)
                     /locus_tag="RD508_002642"
     CDS             complement(4132..4818)
                     /locus_tag="RD508_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7737165.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(4954..5148)
                     /locus_tag="RD508_002643"
     CDS             complement(4954..5148)
                     /locus_tag="RD508_002643"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737166.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5198..5638)
                     /locus_tag="RD508_002644"
     CDS             complement(5198..5638)
                     /locus_tag="RD508_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HDT7737167.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(5642..6487)
                     /locus_tag="RD508_002645"
     CDS             complement(5642..6487)
                     /locus_tag="RD508_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HDT7737168.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6636..8054
                     /gene="pepV"
                     /locus_tag="RD508_002646"
     CDS             6636..8054
                     /gene="pepV"
                     /locus_tag="RD508_002646"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HDT7737169.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
BASE COUNT         2480 a         1515 c         1713 g         2358 t
ORIGIN      
        1 tatttcagta ccggttgcac tgttctcatt tatgggctcg attatggctg gaatctttgc
       61 taatatcgtc aatttcaaac aatatcaaac gatttatgct ggtttcaatc cagcggctga
      121 aagctatact tataatgact atttccaaat tggtatgatt gggatgattg taagcttagt
      181 tgtggtacta acggtcgcta atatatcaat gaacaaaaag aaacgctatg caatggcagc
      241 aaacgtacca gctgaaggtg gcgacgcacc aatgatctca tggttagccg tattattacc
      301 agttttaggg gtcgttcttt tagatcttca aatcatctta ggttttattc tagcaggtat
      361 ctgggcattg ctgtttactg gaaaattgcg cggaggttat aaagaaatct gtcgtcagtt
      421 tgcgaaatta tttacagatg gcgcagtcga tgttgcacca atggttggtt tcttgatgac
      481 cttagcgatg ttcaataatt cagctgcgta tgcttctcct tatttttcag ctatttttgg
      541 agattggata ccgcaatcac cattagtctt ggcaatcgta tttgctatat tgacaccact
      601 aggatttttc cgcggtccaa tgaatctagt cggttcaggc tcagctattt tagctgtcgt
      661 gttagctgtt aatccaacga tgtcgccagc ctttttgttc ccgttatttg caattacaac
      721 gattgctcct cagcatttag atattacaca atcttgggtt gcttggggat taggttatac
      781 aaaagtaact tctcgagaat atatgaagaa atccatccca actggttgga tcatcggtgc
      841 gatcttatgc ctgatcacgt tcttattgta cgggaacgcc tagtaaacaa aacgtcgata
      901 aaaacgatta gataaatgga ggaaaagaaa atgaaacgtt ttgtgcgaat gggaattgat
      961 gttggcggta cacatacgaa agcagtcgca atcgataatg cgacgcacga aatcatcgga
     1021 aaatcttcag tgaaaacaac ccacgatgat gtccgtggag tagctgcagg tgtcgttcag
     1081 tcttttcaaa attgtttgcg ggaaaataat atcagtccag aagatgttgt gtttgttgca
     1141 cattctacca cacaagcgac taatgcactg attgaaggag acgtagcaaa agtcggcgta
     1201 atcgggatgg caaaaggtgg attagaaggt tttttagcaa aacgacaaac tagattgaac
     1261 gatatcgatt tagggaataa gaaaaaaata gagattgtca atgcattctt acctgtcaaa
     1321 aacttaaatg tagaccgtgt ttcagaaacg atttcttctt tagaaagaga aagagcggag
     1381 gtcttggttt cttctatggc atttggagta gataatgggg aaccagaacg agttgtttat
     1441 gaagcagcat ctgtgaaagc gatccctaca acgatggctt ctgacatcac aaaattatat
     1501 ggattgacaa gaagaactcg gacagcagca atcaacgcat ctattttacc aaaaatgcta
     1561 gatacggcaa cctcgacaga agactccgta cgagaagcag gggtcaatgt ttctttgatg
     1621 attatgcgcg gagacggcgg agtaatggaa atcaatgaaa tgaaaaaacg acctgtttta
     1681 accatgcttt ccggtcctgc tgcatcagtc atgggctctt tgatgtactt gagagcgtct
     1741 aatggtgttt attttgaagt aggcggaaca acaaccaata tcggggtcat taaaaatgga
     1801 cgtccagcaa tcgattattc aattgtaggt ggccacccaa catatatctc ttcattagat
     1861 gttcgggttc taggtgtggc aggcggttcg atggtacggg ctaatcagtc aggaatcatc
     1921 gatgtcggtc cacgttctgc acatattgcc ggtctagatt atgcagtatt tacggagaca
     1981 gaaaaaatca aaggtcctaa ggttgaattt ttctctccta aagaaggaga ccctgctgat
     2041 tacgtcaagg tagtgatgga agacggagaa gaagtgacta ttacaaatac atgtgcagcc
     2101 aatgttcttg gattagtgca agaagaacat ttttcttatg gaaatgtccc atctgcacga
     2161 aaagccatac aggcattagc agactattgt catacgacgg ttgaagacat cgcagagcag
     2221 atcatggaaa aatcctatgc taagattgaa ccggtgattt tagaattggc agacaagtat
     2281 cacttggaga aagatcagat ttctcttgta ggtgtagggg gcggcgctgc ctcattgatt
     2341 acttacttta gtaataaaat gggtgtgaaa tattcgattc ctgaaaacgc cgaagtgatt
     2401 tcttctattg gtgtagcact tgcaatggtc cgagatgttg tagaacgtat catcccttcg
     2461 ccaagtaaag aagatatacg atcgttgaaa aatgaagcga tgaataaagc gattgaatca
     2521 ggcgctacac cagaatcgat cgaagtccac gtagaaatcg atccacatac ttcaaaagta
     2581 acggctatcg ctactggttc tacggaagtg aaagcaaccg atctaaccaa ggagatcaca
     2641 acagaagaag cactagagct tgctgcagag gatatgcgat taaataaaaa tgaagtttgc
     2701 ttattggaaa atacaccttt cttttatgta tgcggcgaac agaatcgttc aaaaaatgct
     2761 ggaagtcttc ggatcatcga tcaaaaagga tttatcaagg tccaacgtgg acatgcttca
     2821 tgtatgaaaa caactgcagc caattatatg acagctgtcg aacaactttg ggaagatatg
     2881 gcagtttatc aaactgaatt gattgcccga ccagaatttt atctctgctt aggagcaaga
     2941 gtctctgatt ttacagcgac ggatctggaa caactacagc ttttgatgga tctggaagta
     3001 tctactatgg aaccggagga agaagtgatc gtcgttgccg gaaatatcaa acaaacataa
     3061 gttagaagag ttactaaacg aattacaaca gatccccgaa gaaatttggg gattctacca
     3121 gtttcggcga gatttatttt ggaaaaagat tcctttgtcc aagcagaaaa ttcttataca
     3181 acaatcaatc gattgtggta tcgaaacggc atgtagcatc aaaaaaaagt acccttttgc
     3241 cgatgtagga gaaatctgtg aacaaatggc tgttccaatc gtttcctgtg aatcagagca
     3301 aataaacgaa cgaatcactt ttgcaactta tgcagaagat gaagggatcc gattgatgac
     3361 ggagccgtta gaaaaattaa aatgttcagg actagcttcg atctctaaag aaacagcgca
     3421 agctttgatt attggacatg aactatttca ccacatcgaa gcttctgtta agggaattta
     3481 tacgcaaagc gaaaaaattg tgctgtggcg gttgcctttt tatacacatc aatcaaacat
     3541 tcgtgcattg agcgagatag cagcgatgag tttttcaaaa gagatgaatc aaagcgattt
     3601 ttcgccttat gtattagagg cagtcttact ttggccatat aatgaaattc gtagccaagg
     3661 gatcttagaa gaaataaaag aaatagaaaa aagatgtacg gagtatgatt tagattacaa
     3721 ataaagagac tgtgacaaaa gtcgtgtcac agtccttttt ttccgaataa acggtgttct
     3781 cctgtcaact cctcggtcac aagtcaaaat attcaacaaa catgagaagc tgttttttga
     3841 aattgttcct tgtgactcgg agatgaacgg caggctcacg acctcttgga aaaaggtgtt
     3901 caaaagcttg catctgcggt aataagaaca gccaagttaa aaacataaga agctattttt
     3961 acttggctgt tcttattact tgatgcaggg cagctttttc acaacctctc aataaacggt
     4021 gtgcaatcag ctgaccctcg gtattagctc aaaaaaaacg gcaaaatatg aggaactatt
     4081 ttgccgttta tttctctaat actcaggtca aaacgctgat tccaaaacct cttatttgat
     4141 gggtctgtcc tgaatatctt caaaataatc ggggtaatta tgaatcacgt attcttgctc
     4201 ctcgataatc atatgtaaat gcatcgtgca aagaaatccg acttcatcaa agttatgatc
     4261 aatcattgat tgaagcattg tctgatgttc atctaatact cgaccccagt ctaattctga
     4321 aatcgtcaaa cgtaaccatc tgaaacggtt caagtgcgta ctataacttt ctagccaatc
     4381 ccaaatttct cgttttccag caatttcata acaagttcgg tgaaaatcag tatccaaatc
     4441 aaaaaaagct tttttatttt gagcgatcac tgcctgatcg gtttgttcta gtattttttc
     4501 tagtttagct tgatcttgct tggtcatttt cgcactgcat tcttgcagga tcggtttttc
     4561 caacttttcc cgcgtataac gggctaatga agcagatcgg atatcgattt ttgaaacata
     4621 agtgccggac tgtggaatgg tttttacaag ctcttgattg cgcagttgga tcagtgcttc
     4681 tcgaatcggt gtacgcccga tagctagttg ttcttctaac actttatcgg agattttact
     4741 tccgggtgct aactcggaat aaatgatttg tttacgtata gattcataag cttgctgttg
     4801 caaattattg ataaccattt aaccttcctt tctatgcaga tataatctat tataacataa
     4861 atcgcttaca aatcgtgtgg gcataaaaac acagtctgca aaaaaagccc tgataggcat
     4921 gcctattaga gcctcgaaaa gaaaaatatt gaatcaatct ggtcgtacct cttggatcgg
     4981 tttgacacga ccgccgattc ttttagcaaa agcttcggat tcttttttgt ctttgaaaat
     5041 gagcagattg tctaagtttt tttcccgagt gcgacagcca gttttatcga tgtaaccgtg
     5101 cattacttta acgacataca tggggatcac ctgctttttt cttttcatta tacgaactac
     5161 tcgacacaat acaagaaaaa tgcttagacg gtctttatta agaatttaca tcatccaaag
     5221 aagcgtacgc ttggaataac tgttctaact ccggattgac tttgctcagc ttcactaatc
     5281 gttgcgaatc agaaagtaaa aaacagtgtt tactactgcc agtagttttt aattttttgt
     5341 cttcagttcc cacaatttcg tagctaaaat ccaaccgtgt tcccgtatac ttttggatag
     5401 ttgggtggat gctcactttt tctccgtaat ggatcatttc tttatagctg caatttactt
     5461 ccagaacggg gatgatgatc ccagattctt cgattttttt atagggaaac cctagatgta
     5521 ccaataaggc tacccgagcc tcttcaaacc agcggatata attgctgtga tgaataatcc
     5581 ccatttgatc tgtttcataa taaaaaggtt ctcgcacata acctgtaaat ttctccatga
     5641 ctcatgcctc gttttccatt gattttttac aaaaataatt catccacttc ggaagtgctt
     5701 cgctgatttg tgtcggcaaa acaatatatt gttcttttgc cagctggtct ccaatgaaac
     5761 tatgaagata aacagctgct gcaatcgttt ggtcattttg aggaaactgg gctaaaaatc
     5821 ctgtgatcat cccagctaaa gtgtcaccca tgccgcctgt tgccatagca gcagaaccta
     5881 aaggattggt gtagaagtgc tggtgaccat aaatttttgt ctcatgactt ttcaaaacga
     5941 gcacagcacc gatttcctgt tgcttctttt tgttttcttt atcccgttgt tcttgtatcg
     6001 gtagagaact caaccgttgc cactccattt gatgaggtgt aagtacagtt tgttcgggat
     6061 agggtagcaa aagatgatta gcaacaagta aacttaaagc agagccatca atcaccagcc
     6121 attgttcttt tgattggttt tctagtactt gtttgaaacg ttccaaactc ttagaagaag
     6181 tacccaatcc gggaccaatc aagagtacat ctgcttgctt tattacggaa agaaactggt
     6241 cagtatccgt ccaatctaca atcattgctt ctggcagatg actgtgaaga gcactccgat
     6301 ttttttcatc agttactaca gtcgtgagac ccgctccact gtgtacggca gctaaagcac
     6361 tcataatgat tgctccgcca tattgttcat tgccgccaat caaaacgata cgtccaaatg
     6421 ttcctttatg tgaaatcttt ggacgaggtg tgatgactct tttcactagt tgttcgttta
     6481 tcagcatcga aaaacctcct tttactcatt atagcgtata ttttttttag agaaaaacag
     6541 ataagaaaag gaattgtcag attttttgaa ctattttttt ctgtaatttg tggtatcatg
     6601 aacacgaaga cttaaataag tggaggatta actttatgac aattgattgg caaaaagaag
     6661 tagaagcacg taaagaagac ttgcttgaag acttgaaaaa tcttttacgt gtcaacagcg
     6721 agcgcgatga ttcaaaagta acaccagatg caccatttgg acctggacct cgcgacgcat
     6781 tgaaacatat gttagcttat ggcgaacgtg atggatttaa agtaaaaaat gtcgataact
     6841 atgcagggca tattgatctt ggcgaaggag acgaaacgct agggatattt ggacacatgg
     6901 atgtcgttcc tgcaggagat ggctgggaca cagatcctta tgaaccagta atcaaggatg
     6961 gaaagatctt tgcacgcgga tcaagcgatg acaaaggtcc aagtatggca gcttactatg
     7021 cgatgaagat cattaaagaa cttgacttga aactatcaaa aaaagttcgc ttcgtagtcg
     7081 gcagcgatga agaaagcggc tggggcgata tggcttatta tttcgaacat gaagaagaac
     7141 cagattttgg tttctcacca gatgctgaat tcccaatcat caatggtgaa aaaggaaatg
     7201 tttctttagc tttacgcttc aaaggcgaca atgcaggaga ttatgtcttg aaatcttttg
     7261 tttccggact tcgcgaaaat atggtgccag gaacagcaac tgcagcactt caagtaccaa
     7321 gtgcagatgc agctatcgcg atggaagaag cattttacca attcatcgaa gcaaatccag
     7381 taagcggaac gattgaagcg gacaatacgt atgtaaaaat cgaattagtt ggtaaaggcg
     7441 cacatggtgc aagcccacaa tctggtatca atgcaggttc tttcttggca ttgttcttag
     7501 ataactatga attcctagga tctgctaaac aatttatcca tgtagcagct gcttatgtcc
     7561 atgaagattt ttatggagaa aaactaggag tcgcttatga agatgaaaaa atgggcaaat
     7621 tgacaatgaa tgctggacta tttgcttttg aagaaaatgg tacagaggaa gcgaacttca
     7681 tcaatatgaa tttccgtttt ccaaaaggtg taacagtaga cggattgcaa agtgacatcg
     7741 aacaaacagt ggggcaagaa ggcgcaacag ttactcgagg tgctcgcgta atggaaccac
     7801 attacgtacc aatggatgat ccattggtgg ctacattatt gcaagtctat gaagaccaca
     7861 ctggagaaaa aggctacgaa caaatcatcg gtggcggaac ttacggacgt ttgttgaaac
     7921 gtggcgttgc ttatggagcg atgttcccag gatatactga tacaatgcat caagcaaacg
     7981 aatttatgag tcttgatgac ttgttcagag caacagcaat ctatgcagat gccatctatc
     8041 gtttggcgaa ataaaaatac taaaaa
//
LOCUS       DAPBCF010000087         7851 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.090, whole genome shotgun sequence.
ACCESSION   DAPBCF010000087 DAPBCF010000000
VERSION     DAPBCF010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.090"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(393..710)
                     /locus_tag="RD508_002647"
     CDS             complement(393..710)
                     /locus_tag="RD508_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDT7737170.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTIHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            complement(711..965)
                     /locus_tag="RD508_002648"
     CDS             complement(711..965)
                     /locus_tag="RD508_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7737171.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTVQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            complement(1225..1443)
                     /locus_tag="RD508_002649"
                     /pseudo
     CDS             complement(1225..1443)
                     /locus_tag="RD508_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(1709..1903)
                     /locus_tag="RD508_002650"
     CDS             complement(1709..1903)
                     /locus_tag="RD508_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737172.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(2003..2089)
                     /locus_tag="RD508_002651"
                     /pseudo
     CDS             complement(2003..2089)
                     /locus_tag="RD508_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            complement(2473..3663)
                     /locus_tag="RD508_002652"
     CDS             complement(2473..3663)
                     /locus_tag="RD508_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDT7737173.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKMELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNITKSFTEEVTAFKGRELHDSYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVNNRKEVCDDFKMV
                     YQASSKEVALEARGAFAKKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            4600..5640
                     /locus_tag="RD508_002653"
     CDS             4600..5640
                     /locus_tag="RD508_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDT7737174.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPITAKVSSEKRLNYE
                     SSPSTITKDWLE"
     gene            6464..6796
                     /locus_tag="RD508_002654"
     CDS             6464..6796
                     /locus_tag="RD508_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HDT7737175.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            7415..7756
                     /locus_tag="RD508_002655"
     CDS             7415..7756
                     /locus_tag="RD508_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HDT7737176.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     NEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         2637 a         1251 c         1354 g         2609 t
ORIGIN      
        1 atattggact tcctctttta aaacacaaaa ataaatacta ccttatttag gtagtattta
       61 ttaaaagtta cgtcaatttt gattaaaaat atactacttg aacctctcat gagtaaagtc
      121 acgaaatttt tgggaataga gcgtacttga tatcttattt tttcactaat agcagtgtct
      181 cttattcacc aagcgatccc cgtagttcct acggttctta atttttctct agaccaatga
      241 ttgtatcttt agaccttcgg ccataacatg gagcaaaata aaaaggtact aagtcttata
      301 tatcaatctt cgagtaaccg acggttaaca accatatcga gcggcattaa tcacccacct
      361 gtagaggatg agcgactttt gcctaattat tgttaaaagc ctagtttcat ttgtttagat
      421 tggaaaatac gtcctacaag tatctctttt ttttcatggt cgatccgata aaataaggca
      481 tagcttttgc cgatcacgat ccgatatgtt gggatatcca ttccatagat ttcggaaact
      541 tcctcatgta tagttggaaa atttttggtt agttctaaag ccttctggat cgcacctaca
      601 aatcttttta tgctggctgg agaaagagca agctcatttt cccattcttc tattatcgtt
      661 tcaaggctgg tctggaaact tttagaataa actagcgtgt actctttcat ctattcactc
      721 cagccgtatt ttccgaaagc ttttaccatt tcaatttctg aaactgttaa acctttctca
      781 aagtcttgga aactttcttc aatcaatttg cgatcgtgtt cttttgctat ttgagtagta
      841 tctaatatga ataagttgcc ttcttgtttg gcttggacag tgtctccgct ttttaatcca
      901 agagagcttg gaaggatcac tcccacacta ttgccgatct ttctaacctt tagttctttt
      961 cccatgttat cacactcctt ttagtttttg atgaataaat tataacatgt tataacaaca
     1021 attgccaacg gtgtttctta agggattcca ctccatatta ttattggaca aaataagcca
     1081 cttagaacgc tgaaaacata tacaaacgat atcaaaatac gagtgaacta ctcaccatac
     1141 acttccgtta acatccattt aagtaggtat ttttattgta tatagattta acatatgtcg
     1201 gtcggttgat tgatatagct aaagttataa ctcaaccgaa gccgattcat ctacacgaat
     1261 aaagttgcga gtgttctcgg ctaattcata ataattgtta tgtgttccat atagcaatac
     1321 tggaataact ttattttctt gaatctcata agcaactcta tacacggtga ccgcatactt
     1381 aaatccatta gaccaattac ctgataaacc tccagttttt tgctcttact taaatggatc
     1441 aatagcaatt tcatcacaaa cctatagagg acgagtgact tctgcctaat tacgttaaaa
     1501 aatattgaaa gtaactctat gtagcaaaaa atatctagaa tttcatttcc tcaaaactga
     1561 tcgatattgt atctaaaaat atatactacc taaaataggt agtatatatt aaaatatgtg
     1621 cttttgttag aaaaatcaat acataaatta tcatatctgt atatgtcatt taggtatttc
     1681 agttatgtta taatagtttt gctgtctgct accccggcct aatctggcaa ggggaggagg
     1741 agatataatg aaataccttt ttgattttgt ttttgcaatc aagccatttg cagatgtagt
     1801 gtgcagttac ctctgcaaat ggcttgattg caaaattgcc aaaaaagaca gtaagcctac
     1861 cagttaattc tataatatag aaacgtaaaa aaaaccccat cagcctgcac gctgatgggg
     1921 tttggtgata taatgaaata cctctttgtt actcatagtt ataccataat tagtcacgaa
     1981 tgcaaccaat agaaaaaact acttagaacg gtagatcatc gctaataaca atgcattgtc
     2041 caccaaatgg attttgtgaa gcattaaata cattgttatt aattgtcgct gcttttaact
     2101 aggcctctcc ccttctatta taaaagaaga tatatatcat ttcttaatta cctactacct
     2161 taaaccaaaa tttaagtact acctaattta agtagtactt aaacaatcta aaaaatagtt
     2221 atcccaattg ttatgctttt ataatacgat tatttgtaac aaaatgaata ttatataatt
     2281 aaacactacc atatttaggt agtgtttaat tattagcaaa acaaaaaata tttattctat
     2341 tctcttaact tcaactaagt tatgctgcac acctttatat aaatcatatg caactcatta
     2401 gctagacaaa ctacaagcat ggggagcgtc aataattttg tgtaaatggt tcctccctac
     2461 tgtagattgt ttctaattct caatcagttg gcttagcatt tgttcaagtt cgccttcggc
     2521 ctgttgaaag cctttatgac tgcgacctag gaatttttgg ttgtaagtat caaaagacga
     2581 gactaagaaa cgttccatcg actcttcgtt ttggaactgt tccttgcggt ggctgtattt
     2641 cttgatttgc ttattaaagg attcaatcaa gttcgtagaa taaatactct tgcgtatggc
     2701 caaggggaaa tcatagaaag tgagcaagtg atcgttcgaa agaatcgatt caaccacttt
     2761 tggatagctg gttttccatt ttttcgcaaa agcaccacgt gcttccaacg ccacctcttt
     2821 agacgaggct tgatacacca ttttaaaatc atcacagact tccttacgat tattgacacg
     2881 cactttgtga ctgatattac gggaaacgtg tacacaacaa tgttgaaaac gagctttggg
     2941 atagaaccga ctaatcgctc ctaccatccc ctttaagcca tccgtgatga acaggaggac
     3001 atttttcaaa ccgcgctctt gaaggtccaa taaaatttcc tcccaaatcg tgatggattc
     3061 agtcggtgca atcgcatagc tcaatacttc ctttgatccg tccgggcgaa tgccaactgc
     3121 gatatgaata gcttccttgg cgacggtttt ccgctttaac ggaatatacg ttgcgtccat
     3181 ataaatagca gcataactgt catgaagctc ccgcccttta aacgccgtta cctcttctgt
     3241 aaatgatttt gttatattgg acatggtttg gggcgtgtag tgatgcccat acattttctc
     3301 aatcaagtct gcgatttccg acatggtaat accttttcgg aagaggtgaa tgacggtctc
     3361 ctctaaggta tcattcgtcc gtctataagc gggaacagtc tgttgcttga actcgccgtt
     3421 gcggtcgcgc ggaatctgga gatgaagttc cccgtactcg gtcttgaccg tacggtcata
     3481 ggagccgtta cgagaattac ccgtgttaaa accaatgcga tcgtactttt cgtaatcgag
     3541 gaaagccgtt aactccattt tgagaagcgt attgacagct ttttccaaat ggacacggaa
     3601 taattcattc aaatcgcctt tgttcgctag agtctttaga atttctgtag taaaatcgtt
     3661 catatggaag tcctcttttc tgtgaatgtg ttgtggtaac tctattctac agaagggact
     3721 tccttttttt ctatttacac aaaatatttt acactctcca agcatgtagt tttatctgtt
     3781 aattatgtac tacctgaata aagtagttta taattaacaa gtatatatat ttaaaaattt
     3841 aagattaatt tttttatgac ttgtacaaat ttatctgata ttctcttatt aagaactacc
     3901 taatttgggt agttcttatt ttttacattt taagtagtat ttaattgcaa tttggtagta
     3961 tttttttatt atcttattct tagaacggta gtacttaata taaatatagg tagtatctaa
     4021 tttaagtatt aatggtagta tctaaattaa caggtagtat gtaactactt taaagtaatt
     4081 tttttcagat taacacagta gtatcttatt aaataagtta attttaatgg tagtacataa
     4141 ttattatata tatctgaaat tggtagtact tattgtattt tttagtagta tataatctat
     4201 tgttttctag cctaaagcct tgtcttataa gaataatata atatatacta ctgaaataag
     4261 gtagtatata ttactagtaa tggtagtatg ttttatatgc ataaggtagt tcttaattta
     4321 ttttttgttt tgacactggt agtacttaat tatctttaat tttaaaacta aattttattc
     4381 atacgttttt ctggtagtat ttaattataa ataatattta tttaaagtag ttcttaatga
     4441 ctttaaaggt agtacataat tcattttatt tctgatttta ggtagtattt aattaaaaaa
     4501 cagttttaat gcgtttgcat tttttattta tctttgctat tttcgaaaag agtaggtaat
     4561 tttacataaa taaaacaacg tgaaagtaga ggatctacaa tgactgattt taaatttttt
     4621 aaggcggata gagtttacaa cgaattattt tatcaatttc caaaagtctt tattgtttct
     4681 gacgaataca aaaaaatgaa agattcaact aagattgcct atatgctttt aaaagcaaga
     4741 ttagagatcg caatcagcaa acggcaaatc gatgaagaag gtaatgttta ttttacttat
     4801 acgacaaatg aactatgtag agtattaaac tgccaaaaac aaaaagcgat agcaatcaaa
     4861 aaagagttgg aatcctttgg tttattatta caaaagcaga tgggatttaa caaacagtta
     4921 gggaaaaata atcctaatag actatatcta gcagaattaa aagtctcaga aaatgatatc
     4981 tacttactcg aaaaatttga tagagagaat agggaaaacg ttgataaatc agagggtatg
     5041 aaaatcatac ccaccctcga cgaaaaatca gacgctgaat cccttggggc tcaagagggt
     5101 atgaaaatca taccgtgcca aaacgttgat aaatcagagg gtatgaaaat cataccagaa
     5161 cttaataata atatattaga cactaataga cacaatatag acactgaaaa agaccgccta
     5221 caagatcaat tgttgttaga caattttgag acaattatga caaacgacag cattgctacg
     5281 tttgtccctg aacgagtatt aaatttgata aaaacatttt cttcaagtta cagtgaagct
     5341 caaaaaaccg tccagactat tcataatgca aagaaaaaag ctgaaataga aagtggtatt
     5401 tcgatagttt ttgaagaact cgatagttat tatgtcaatg cagaacaaga attatacacg
     5461 acactgttaa aagcctatca aaaattaaaa accgaaaaag tcgaaaatat ccagaacctg
     5521 atttttgtct atgtaaaaaa ttggtttatc gaaaaaccaa taactgctaa agtatcaagt
     5581 gaaaaacgtt tgaattatga aagctcccca agcactatta cgaaagactg gttagagtga
     5641 aactttactg acaaagtgat tgttgcttca tggagtaaca ttaaaattaa aaatttttta
     5701 ttattctaat tatattacga atattataaa ataatagcta ttttaataga atttataagt
     5761 taaaatatta tgataaaaat cacaaacgta gccttttacg tcataagtgt taaaagaaat
     5821 aattaatttc aaatatagaa aagggaacgt atgtttgcat actccttttt tttgagttat
     5881 aataatacgc gaagagagat aatttcatta tttaaacaag ctaaaaatct tgatattact
     5941 tcttttcagg caatacgaat attattcgct tacatttttt gtataaattt aattgtctgc
     6001 tatgcttgtg atgaattgat tttcgttctg cacttttgga tgataaattt ggacaattga
     6061 aaatacaaaa aaaagaaagg cggtatgaac tcggaaggct ggtaaccttc gtcagcgttc
     6121 atacacggca ttaagatttg gcccttaatg cgttaacctt tcagtgttac ggtattaccc
     6181 gcaatggatt tagtataaca gatattcaaa agtgatacca ctttttttgg ctgtgttaag
     6241 gttaaaaata cgtgatatta cgatgaatct atgcctaagc ataatgttat aaaaatgtcc
     6301 gtgtggctct ttgccgtatg acgaacgctg aaattagagg gaacgcatgt ttggatgcgt
     6361 tccctctttt ttgtttgtca tgaacgaaaa tcaattctct atttttgaaa aataacaaga
     6421 aaaacttgtt aaaaatattt aaagaaattg ggtggtttat tttatgtcat atacaggaat
     6481 tttgagtctc aaagatattt gtcactacgg taaacggtgt accgctacag agaaaatcac
     6541 gaagaaacta tcaactggcc aaagtaaaac cgttgtgcag tgtaagaaat atataatcca
     6601 gaaagacaaa gtctcagagg aaatgattta ttacattggg aaacaaaagc aaataatttt
     6661 aaaagatcct atccccttaa aagagctata tccaacaatc aaacatgttt atgaccaaaa
     6721 cggtgtactg attggtcgaa gaaaaaatgg agtcttgcgt tgtaccgcaa aagggatggg
     6781 gcgtttaatc agctgaattg atcattctca taacttgtat tttatcgttt ttcgcttgct
     6841 tgaaaatatt gtcgagactt ctaaaagaac ttagaatcat tagaaaaata aggagtagac
     6901 ttgatctatc aacaatttcc ttcggggagt gacggggtag atttttacga ttggtaacgt
     6961 aaaaaattgg tcaatcgagt aaatgcgctt gtttggatag tggtgaaatg aatttgtgta
     7021 aataatatac acagagtaaa caagagggaa tttagaggtt agacaagtta gaatagcgcc
     7081 tagattaatc atgagcagct actaagggat ctaggctttg acgcaaactc atggaataag
     7141 gagtaggtct tctcgtaatg gggaggacgc acaagaaatt gtgtcgtgtg ctgcagtaca
     7201 tgtagatact tgcgaggacg ttggtcattg gatcaatcga gcatttaccg ctgtctacta
     7261 gggtttctcg tttcggacgc cataaacgag tcgatatttt ttatgtattt ttaagtaaac
     7321 gaaaaacgat aaaatatgaa cgagtcctga ataaagtgaa aaaattgata taaaacatag
     7381 agaaaatgaa atttacgtaa tggaggaatg acaaatgaaa aattatgatc cgaatatacg
     7441 attgggcaca catactatta aggtttcttt ccaacgttgg gattacaaag gttttgtgac
     7501 gtttagaaga ggcggaaatt gtaaaggatt agatgtttta gcattaaacg aggatgattt
     7561 atacgatcaa acattgactg ataatccaat tggattcggc ttgctacctg aagatgatga
     7621 aggtaatgaa tggtttaaaa tgacgcttat gaatgataat ggagacgaat tatctgttga
     7681 agatacttgg tcatatttga gtgattatat tgtcagcttt gaaatcattg aatttgtagc
     7741 ggataaagaa gaataaaaac tggaggaata aattttacag ataaaggctt agaaggagtc
     7801 acgacgatta ataaaaaggt agtattacct taggcattga gtaaggaatt t
//
LOCUS       DAPBCF010000088         7762 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.091, whole genome shotgun sequence.
ACCESSION   DAPBCF010000088 DAPBCF010000000
VERSION     DAPBCF010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.091"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..189
                     /locus_tag="RD508_002656"
     CDS             <1..189
                     /locus_tag="RD508_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDT7737177.1"
                     /translation="KLQNLLTYEEGITNAMIYPYSNGKIEAKNTHIKTMKRVSYGFKS
                     FENMRIRIFLINQLINVR"
     gene            complement(368..697)
                     /locus_tag="RD508_002657"
     CDS             complement(368..697)
                     /locus_tag="RD508_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDT7737178.1"
                     /translation="MNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSKYH
                     TKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQRL
                     EERMEEL"
     gene            complement(687..959)
                     /locus_tag="RD508_002658"
     CDS             complement(687..959)
                     /locus_tag="RD508_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HDT7737179.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(1410..2213)
                     /locus_tag="RD508_002659"
     CDS             complement(1410..2213)
                     /locus_tag="RD508_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDT7737180.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(2191..3315)
                     /locus_tag="RD508_002660"
     CDS             complement(2191..3315)
                     /locus_tag="RD508_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7737181.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(3331..4146)
                     /locus_tag="RD508_002661"
     CDS             complement(3331..4146)
                     /locus_tag="RD508_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7737182.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(4136..5008)
                     /locus_tag="RD508_002662"
     CDS             complement(4136..5008)
                     /locus_tag="RD508_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7737183.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            complement(5093..6382)
                     /locus_tag="RD508_002663"
     CDS             complement(5093..6382)
                     /locus_tag="RD508_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7737184.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(6526..7037)
                     /locus_tag="RD508_002664"
                     /pseudo
     CDS             complement(6526..7037)
                     /locus_tag="RD508_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7104..7247)
                     /locus_tag="RD508_002665"
     CDS             complement(7104..7247)
                     /locus_tag="RD508_002665"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDT7737185.1"
                     /translation="MITAHSGSDNTEENSWAFLRFCLDRQLCFEVDVRQQTDGTLILA
                     HDR"
BASE COUNT         2408 a         1662 c         1193 g         2499 t
ORIGIN      
        1 aagcttcaaa accttctgac ctatgaagaa ggtatcacca acgcaatgat ctatccttat
       61 tccaatggaa aaattgaagc gaagaatacc cacataaaga caatgaaacg agtatcctac
      121 ggatttaaat cattcgagaa catgagaatt agaatctttt tgatcaatca attaatcaat
      181 gtaagataac aaaaaatctg aaccagaatg tggttcattc tgacccggat ttgattttgc
      241 acaactcatc agtccttatt gacaaagagc caaaaatctg agccagaatg aggttcattc
      301 tgacccagat ttgattttgt acaacccatc agtccttatt gacaaagagc ccttcttttt
      361 agtattatta taattcttcc atgcgttctt ccagtcgctg taaatcgctt ggacttaatt
      421 ccccaatttt tttccatttg acctttttgt tgtttttggg taattcgttt agagttccta
      481 cgtcaatcca agattctttt tttagtcctg cctgtttcca atcccttatt tcaacgtatt
      541 tcagctttat tttatcggat ttagtatgat attttgaagt aattgacaga aacgaaattg
      601 tgtccagtcc attttttaga atatagacag gccggcgttt accgccctct gcagctgtga
      661 aagcaacgta gacggttgct atatcattag tattcatctt cattgaacca ttcttcaatt
      721 ttttcgtcag tgtctagttt ttggacaggc aatttttccg ctaatctttg aatattatgg
      781 attcgtttac ttttttccga caattcaata gaaaatggga tttttccttg ctcaacaatt
      841 tgcttataaa aaacggtgac ggctgttttg gggctcatgc ctagttcatc aataatgctt
      901 tctgcttcat ttttcaattt ttcgtccata gaaatttgta acttagccat tttctccacc
      961 tctttctgac aaacacatta tatcacggaa agagttcaaa tggaattaat acaactactt
     1021 ttgaactcct tgaaatgcag tgtatttatc taaatataag gaaaggatat agtgctaaat
     1081 ggccttgata gatagaaaag tttcaaaatc cgccacagcg ataattgaag cgaacactca
     1141 acgacacaca gaacaggaaa agactcctaa aagaaccaaa ttaactagga cgtgtctgaa
     1201 aactccacaa agatgtggta tgctctggta aaaaacgaat ggcacaacca cgaagaccga
     1261 tatggttctt ggaaaacttt ctccaccctt tttgtaattg gagggatagt ggtttattga
     1321 tagcgatttt ccaagttctt caagtggaac cagacattga gcaccacggc taaaaagtga
     1381 atgaagtctt tatttttaat caataatttt taatgattac cagtaattgg ttttttcatg
     1441 cgccctattt ctatttgatg tggagttaaa taatgctgat aagtaaaaat ttttccgtca
     1501 attaaactgc cactagtgaa tcctgttcta ttggtaaaaa gagaatagtc tgggtattca
     1561 tctacaccaa atgataaaga ttcagccata aactgttttt taccagcaaa ttcagcactg
     1621 ctaccttgat ggatatggcc tacaaaaata cctaaaatat cactttcggc aatcaattca
     1681 gcaaaacctt ccggaacttc agttacaata gatggatctt cccacgacaa tggatgatga
     1741 accaataaaa tcgttccctt ttcagcaggt gtacccaacc actcttgtaa ttgaatcatc
     1801 tgtcctatcg atatttttcc ttcgtgctgg gtatcttgag cagaatccaa ggaaataatt
     1861 cgtaacccat tttgattcgt acaatggata tactctcccg tttcattgct ttcaacactc
     1921 attccttcaa agaaaacact gcgacgatca tgattcccac gacaaaaata gtaaggtgtg
     1981 gttgggaaat attgatccaa cattttccgt aagacttgat aatcagaaat ccccccttca
     2041 tgtactaaat cacctgttaa tagaataaaa tcgtacactg ttaacgagag ttcttgtaac
     2101 aatttttcca atgccaactg tggattttta attgttggaa atagttcagc agtaaacaag
     2161 ttagtttgat agttttctct aaaatggata tcagagagat gcaaaaagcg catggctatt
     2221 ccctctttct tcaataaaat aatcaggata tcctaaattt tcttgcgtct gataatcaaa
     2281 aaaatgcatt ctttcaggtt ctatgcggag attgactgca tcaccaatct gccaagtagg
     2341 tttttcatta aggacaatca tttctatacc atcgacttta acggtgtacg cataactttg
     2401 acctaatagc tcacgatact tcacttgacc gtgtaaatcg cttgtttctt ttgaaaaggt
     2461 tacgtgttct ggtcttatgc ctaaatacaa tgagccacta acctgaagaa gttgtttttg
     2521 ccaagctgga ttcaatgtta aaaattgact ggctaccttt aatgttcctt gatcataagt
     2581 aactggcata atattcatgc ctggcgaacc aataaaattt gcagtaaaag tatttttagg
     2641 tttcgtataa acatttttcg gcgtatcaat catctgaatt ctaccttcat tcaataaaac
     2701 aatccggtca gctaacgtca tcgcttcaat ttgatcatga gtgacgtaga caaaagtttg
     2761 tttataacgt tgatgaattt ttaccaattc ttttcgtgca tccaatcgta aacgcacatc
     2821 caaatttgat aacggttcat ctaataaaaa ataattactc cgtttaacca ccgcacgagc
     2881 caatgctaca cgctgccgtt gccctcctga caaatcttta ggaagtcgat cttggtatgg
     2941 cgttaaacct aacatcttca aagcttcttc caaacggtgc tgaatgtcag ctgtcttaat
     3001 tttattcgcc cttaatgcaa aaataatatt ctcctttaca gtcatgtgag gatataaagc
     3061 ataattttga aaaaccattg cgatctctcg ttctccacaa ggtagcttat ttgctagttg
     3121 tgtacctaaa aaaagctctc cactcgtaat tttttccaaa ccagcaatca ttctcagcaa
     3181 agtagatttt cctgaaccag atggtcccag taacacaatt cgttctccag cggccacagc
     3241 taaatcaatt tcttttaaaa tggtatgttc tccatatttt tttccgatat ttcttaattc
     3301 aagcgtttct cccatgattt gtcctccaat ttatttaata cctgcagaaa caaaagtccc
     3361 gataatatat ttttgaaaaa ttgcatacaa gactaacggt acaaacattg taattaaact
     3421 aatcgccatt gctacggtaa aatttgtccc accttcagaa ctaatatagg tctgcatcgc
     3481 caacggcaaa gtataattat ctactgtccg taaaattaat accggccaaa catactcatt
     3541 ccaagaggta ataaaaaacc aaataccggt agaagtaatc gcatgtctag taagaggaaa
     3601 aacaatttta ctcatgacgg ttgtttgttt gatgttatcc aatgccgcca catctagaag
     3661 gctcactgga atttcccgca ttgtttgcgt caataaaaaa atgcccatcg catcagcaaa
     3721 ttgtggtatt atcacacccc aagtagtatc aattaaatta agttttgcaa tcaacaaata
     3781 attaggaatc atcgcaacag taaaaggaat gaacatcgta ccaatgatga taaagtacca
     3841 gattttcttc cctttgattc ggcaataagt aaaactatat gccgcaaaaa aagctacgcc
     3901 taacttaaca accgttataa ttgtagcaat aaaaaaagta tttctcgtaa ttttgataat
     3961 tggaagattt tcgaacaaat agcaaaaatt ttccaaggta aacggctgtg gtatcaaact
     4021 agtaatcgtc tgataggcat ctttcaatgg cttaaaagaa ttggccataa taaacaataa
     4081 tggatagata ataatgatta tgatgaacat aaataagaga tgtggcaacc agcgtttaat
     4141 tttcatagta aacccccttt tccacaaatt taaatattac ccctaagaaa acagcaaata
     4201 ttaataaagt taaaactgaa attgctgaag attctccgac tttatacatt tcaaaagcct
     4261 tttgataagc ataatagatc acgtttgcac taccattatt cggtccacca cgagtgatga
     4321 tcttaatcgg agtaaacaca tactgcagac cttgaacaat ggtcatcacc aataaatata
     4381 gtcctgtcga actactcata ggcaacacaa ttgtaaaaaa aatgcgccag atgggtacac
     4441 gatccaactt agctgcttcg atcatctctt gatcaattcc cacaattgct gcaaaaatga
     4501 caatgaaatt ataaccaaaa actttccaag cagtaatacc tgcaatcaca gcaattaccc
     4561 aaccttgtaa attcatccac ataggcagtc ttaaaccaaa atttcccaac aagacagcaa
     4621 ttggtcccga taccggattt aatatccatg taaaaaccat ccccgccact accaaagaaa
     4681 tcacagctgg aataaaaaat aatggtttat acaaattctg ccctttttct ataactattc
     4741 ctaataaaaa ggatgtaata tatgggaaca cacagctcag caagacaaat agaacggtat
     4801 aggacaaagt attcttcaac actttatgaa agactggatc agtcagcacc tttacatagt
     4861 tggcaaagcc aacaaattct ttagtggggg ccaccatatt ccagtcaaaa aaactcaaat
     4921 agatcgtata aatcaatgga taaaaaacaa acacgcccaa caaaataatt gctggcgcca
     4981 gatacaaata acctacatag cgcttcattt ccgacagcct cctcatcctt atgtcaaaag
     5041 cagacgacct tgtttttcct ttcttacagg cgctgtcgtc tgcttgcttt gcttatttga
     5101 gtaactcatt aatttccttt tgagtagctt tcatcgtttc attgacggaa ttacctgata
     5161 aaattttatc ccgcatatcc aacaattttt gttcagcttc taatccagca tctccaggaa
     5221 atgaactcca actgaccatc ttatccatct gatcaattgc tggtatcatc atctgatttt
     5281 cagctaagaa agcttttaat ccattttggg cgtctgcaac atctttacgt ggtggtaaat
     5341 aaccagtacc ttctgtccat ttagctaaag attcaacact ataaagatat tttaagaaat
     5401 cccaagttgc ttcctttttc ttatccgttt gtgatgtaac agctaacatt gcgccaccag
     5461 caggtagttt aacttttttc ccttcccaac ttggtgactc aactgcttta gcagtaaaag
     5521 tactattttt ttgaatgttg tccctttgag caatagtggt atagaccatc gcgacgttac
     5581 catcaataaa gctttgcaca ccttgttccc acgtagtgtg taatgccgtc tggtctttta
     5641 ccatcctttg atataattca taagcagcga taccatcttt agaagcaaag gtagctttgc
     5701 catcttttat tacacttgcc ccattacttt ctaaaattgc ttgttgtgcc caattatcag
     5761 caggttcttg aatatacacg ccatactttc cagttttttc ttttattatc ttagaaaaag
     5821 tttgaacttc ttcccaagtt tttggaccat tttcatccaa gcccgctgct tttaatatat
     5881 cttgatttaa atataaaacc ggattactaa tggagtaagg aatacccact tgtttaccat
     5941 ctttttcaga cagtgccatg atattgtcta aaaaatgatc tttaaaataa tcagcattat
     6001 ccggatccac ttcttctact aaagattgag gattagtata tttgaaattt tctgcaaaat
     6061 aatctttaaa agcccatccc acttgtacta cgtccggtat ttctttggag gcaacagaag
     6121 cttgtaaatt ttgcatcaag cctttataca tatcaggatt atattttgct acaaccttca
     6181 ctttgtcttg agattgattg tatttatcta ctaattcatt cactgttttt ccacctaggg
     6241 tatccgcatt aacatgccaa tactctatcg ttacacgacc ctccgatttt tttgttgtct
     6301 tggtattccc actaccacaa gctgccaaag agatgacact taaaacagac acaaccccta
     6361 taacaagatt tttctttaac ataacattaa cttcctccta atttctttat ggccattttt
     6421 ctaatcaaga aatattatga actaccaatg taaatttcta gttaattttc tgtaaataat
     6481 tcgaaatttg tgcatttcgg ggtacagggt cactggacat atccatcaag ctaagaataa
     6541 agcccccata tggtcatgta tcccatctcc aaatctctta actcctctgt tttgattata
     6601 aaatagttta ttctgtgctc ctttcttcca taaataggcc catgcacaac gtgaggttat
     6661 attataaaca ccacagcgcg caaggtactc aatcgtttct agttcattga ctgtccatac
     6721 agaaaatgtc aatcctagct gctgccccac ttcacgggcc aacttagtta accatccttc
     6781 atgaatattg acgatttgaa cgctttgata ggctaatttc tgtaaggtat cgatcaaatc
     6841 tgcttcggta atatccccaa gttttttccc ttcgaactga ttttcaatat tataaaatat
     6901 atgctttccc caaatcgcag cccaagataa ttgtacatag ccactaagaa caatttgtgg
     6961 ccagattgat aggtttgtgc cagcgaaaaa acggccattt ccaatccctc ttcttttaaa
     7021 tcacagttaa tggtcatggt tgccttctca ttggccactg cttgaaacac ctgctcaagg
     7081 gttaccgaat ctgggacaac ttcttacctg tcatgggcta gtattagcgt accatctgtt
     7141 tgctgacgca catctacttc aaaacaaagc tggcgatcca aacaaaagcg aagaaatgcc
     7201 cagctattct cctccgtatt gtcactacca gagtgtgcag tgatcatggt cattttgacc
     7261 cctcctttaa ttccgtgatt ttctcccaca cgtccactat accgatgaag cgttaatttc
     7321 ttgttaattt cttgtaaatt ccctgcgttt tttcagtaaa ctagttgtaa atcttgcatg
     7381 ctccttccta cgaactcatg aatcgtcgat tttgcccttc tagctagttt caccaattaa
     7441 gtagttctac attccccgct tttaacctac tacacctttt tttgttttca gctattcctt
     7501 cttcttgctg aaagtccttg aggttctttc ttacaggata ccatcaaggt gttcaatggc
     7561 ttattcccat tgaatgaccg agacttacta tcagatttct gctcgttgaa ccaagtcttt
     7621 gatacaggat ttcttccgtc atcttctcac aaataccacc ttgcgtttct ctagcgattg
     7681 gtcgatgtgc accctcccag tggactgtca ctaccccttt ttgctatgcc tagcccacaa
     7741 aaaaagctgt cctcacagac ag
//
LOCUS       DAPBCF010000089         7628 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.092, whole genome shotgun sequence.
ACCESSION   DAPBCF010000089 DAPBCF010000000
VERSION     DAPBCF010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7628
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.092"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(16..708)
                     /locus_tag="RD508_002666"
     CDS             complement(16..708)
                     /locus_tag="RD508_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7737186.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1145..1714)
                     /locus_tag="RD508_002667"
     CDS             complement(1145..1714)
                     /locus_tag="RD508_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDT7737187.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1788..2111)
                     /locus_tag="RD508_002668"
     CDS             complement(1788..2111)
                     /locus_tag="RD508_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737188.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2265..3077)
                     /locus_tag="RD508_002669"
     CDS             complement(2265..3077)
                     /locus_tag="RD508_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737189.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3431..4279
                     /locus_tag="RD508_002670"
     CDS             3431..4279
                     /locus_tag="RD508_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDT7737190.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4424..5365
                     /locus_tag="RD508_002671"
     CDS             4424..5365
                     /locus_tag="RD508_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HDT7737191.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5355..7526
                     /locus_tag="RD508_002672"
                     /pseudo
     CDS             5355..7526
                     /locus_tag="RD508_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2273 a         1512 c         1372 g         2471 t
ORIGIN      
        1 agaggggggg attttttatc gttgtggaat atttaaatac caacgcttgt catgaaaatc
       61 ttgtgctcca cccttagtat ttccttctgg atcgtttgtc gcacgcatca tgacgtatac
      121 tttcttatta gggaaatcac gcatattgaa agatacatga tagccaacat ttcctaaagt
      181 attataagct tgatttacgt ctggtctata aatcccatca gctcttactc tagctagttc
      241 ttttccagta ttgtagtcca taatgaaaat atactcgtat ttataattag caatgtgcca
      301 tccagctaca tgcaagtttg cgttttcgat ttctccgaac tgatcaatgt gggcgtaatt
      361 tgttccatct gtcagcgtag aatttgcagc acctgctcga gttggatcaa ttactggttt
      421 atcctccgaa gtagttggat tatcatccgt aaaaccatga gccaaatcat aggctagttt
      481 ttctttactt acacctattt cagaaagata accgtaagga tctgtatgat cgccccaaat
      541 attttgtgtt acccataaat gcgatttgat tcctggttgg ttataaggag tgtctaatgt
      601 taatggaata ccatatttca ttgctgaatc tcttgccaat tcaacgtata ctttatagtt
      661 cttttcaaaa gtttctttat catgtgtgtg ttgtaactcg atttgcacag gacttttggc
      721 tcacgaggtt gtcctactct acatcttgct gatagatatg ctgaaaggaa aacaccaaca
      781 ttatgttttg ctttttcagc tagaacgaga caagcaggaa tacctttaga agatatcaaa
      841 ggttttttag gtcataaaga tgtttccact acacaagtct atgcccatat ttctcccgaa
      901 gtgaaaaaaa gatcaatgaa tcaactagaa aactatatag aagagcaaat aaaaaagcac
      961 tcaaattgag tgctttttta agctcactat cactaaaact atcactaatt ttatttataa
     1021 gcgaacatgt ttctatcact gattttttaa atctagcgaa aaacccttat cttaaaggcg
     1081 ttcgttcaat tctttggcaa ggtcttcaaa gcctggcttg cctagaagtg cgaacatggt
     1141 tttcttatag ctcatgtaga aaaattttct tgatgatgat tttatccatc aattgagatt
     1201 gactgttttg ctctcctatg atttcagcta tgattgtccg attttgcggt tttcttctta
     1261 actggtagtt gattttccca gtttccatca actcgctaag catatccacg actccgccaa
     1321 atccggtctt tttcgtaata aaacctagtg ctaccattcg ttcatctaga ttttttgctg
     1381 taatcgtcac accagtaatg agcgagtgct gtaatgtttg ggccagctct tccatccctt
     1441 cagcattgga tacgacggaa gctgttttgt taataggttc ttcgtttatt tcttttggtt
     1501 ctttcctctc cactttcact gtttgacgaa ggacatctag ttcttgcaag agcgtttcgt
     1561 attgttcttg ggtcagcatc acgccagcta ctttttcacg attaaatata tatacgccag
     1621 ttcccgcgtc tcgcgcttga gcaaatacat ccatcggcga tcgtttcact tctgtgatcg
     1681 aagatgtggg aacttctaat ttctttaatt ccaatggatt tcctccttta ctaatcgctt
     1741 tttattatag cacagactga cttgttttga tcttttttcc aaaggtttta tcggtttttg
     1801 cctaaccagt aattgatatc ggtaagaagt ctttcgatac caaatgaagg atggtacaga
     1861 tacgtttttt gatcttcgtt atggtctagt ggaaaaaaat gatcgatgat cactagatct
     1921 gcataccgag gcggcttatt tcgagtacat acatgtatag agatccgttt tcgatgtctt
     1981 agcgttttgt tcagtacccc agcaagtctt cttgcttctt ggtgttcata gcgaaaaaaa
     2041 aagacgattt tcacttcagg agggtggaca tctaaatacc ctcgttcctg gagtgttttc
     2101 agtaaaagca tcccccactc tactgcgggg tgtgcaagtg cttgttggat cgctagccga
     2161 aattgatata gtttatcttt ggaattggga aatttttcta atgtttcctg ataataacga
     2221 acttcttcta tcagccggtc atggatacca attacgtaac gaagtcattc ttggtaaagt
     2281 acttttgtca gctttgattt gctttcgctc tcaaattcgc tattcagcca aaacagcgaa
     2341 tcaagctttt cagtcacaat cgtcaatttc cgatagtctt gtgtctcttc tatccgtttc
     2401 caccgctttt cagtaatctg gttacagctc aagcgcaaaa ttgctagata atttttttct
     2461 tttattggca aaatctgctc ctctctaaat agcaattcag gaaacaattc aaagaatagt
     2521 gttcgactgt ctcctaaaat ctcgatttct gccggatcct ttctttgctt caataattgg
     2581 atgaacatct cagaaaagga ctgctctcca tcatctgcaa aaaaatgcgg aaaatctttc
     2641 aaaaagcaaa acagcagata tcttactttt ctttctgaac caaagatctg tgctttttta
     2701 taagaaaaag aaaggtggta ctcgccaaac cactttctca atcgctcttg cgtagaacga
     2761 tcgtacttct gctcgtaagg ttcattcaat agcagatttt tcagtaaaca aaacgggggt
     2821 gattggatca gaaaaacaaa caagagataa ggttcgctat atccttgatc ataaactaac
     2881 tgaacggttt tcttatgaag aatcagctga atgggacagt cgctttccgc caaacgtttc
     2941 agatgccgat ccactgtttt aacatcgatt ttcagttctt cagctaaatc agcttttcgc
     3001 cagatcaaat ctttcattag attgattagt gaaaataaat tctgtgcatt ttttgataat
     3061 agtttttgcc atctcatcga tcatttctca cctgatttct aaacatattg tttgatcaaa
     3121 atgggttcac tcctaaaaag ataaaaaact ccctttctat ttatttaaat acgcaaatct
     3181 tcctcattat tttttatttt actcaattta atcgtattct catttcaaaa cgaatgtact
     3241 ttaaaaaaac ataataagat cactttgctt gtaggatgta ttcccttcca ttacaatgaa
     3301 ataaatagcg attttatgag aaggtgatgt gaaaatggaa gaaaaaatag aagaatccaa
     3361 acaaaaaatc gatcagttga tataagaatt agaaaaagcg gtcatcggca aacgttcaac
     3421 tatccaattg atgatcgtgg ccctattagc aggtggtcat gtcttattcg aagatattcc
     3481 cggtgtaggt aaaacgttac tggtcaaagc actagcaaaa gctgtacagg gaaccttcag
     3541 cagagtccaa tgtactcctg atctgctgcc tagtgatatt cttggttttt ccgtatacaa
     3601 ttcacaatca aaagagtttg aatttcgtcc gggaccgatc tttaccacga tcttgttagc
     3661 agatgagatc aatcgtacga ctcctcgtac tcagtcagca cttttagaag caatggccga
     3721 gaatcatgca acgatcgaca acaatacata ccctctagac aatcattttt ttgtcttagc
     3781 tacgcaaaat ccaatcgagt acgaaggaac atatcctttg ccggaagcac agctcgatcg
     3841 ttttttattc cgactacaaa tcggttatcc ttcttttgat gacgaacttt tgctactttt
     3901 ggataaattc gaaaaagtgt tggataactt aaatgaagta ttgaacagtt atgaaataga
     3961 agaaataaaa acaaatgtgg cgaatgtctt tgtcagtccc gaagtggcat cttatgcctt
     4021 gcagttagtg tcagcaacaa gaagtcatgc tgccatccag cttggcatca gtccacgagg
     4081 aagcctttcc tttattcagg cagcaaaagc ttatgcttta atccatggga gaaattacgt
     4141 cacgcccaaa gatttgcagg atttagttcc ttacgtgttt tcccatcgcc tgatttttta
     4201 cgatcgttca ttgaaggaag acgaaaagaa acaaatcatt catactcttg ttgcacaaat
     4261 tcctattcct gtgaggtaga ttgaggtaga caatggaaaa aatcaaagat tatttcatta
     4321 attttgtgtt atttctggta tatttcatca ttgtgctttt tgctcttgta ttcaacaatt
     4381 ctttaggctg gttcttgttg gcctttttta ctctttatgt atcatggagc ttgatttcat
     4441 taagcagctt tctaaagaaa ctttcggtta cttgtacatt gcagccactc gtttatcgca
     4501 aaaaaagtat gcaggttatt ttttccatag caaaaaagag aactttttct ttacctctcc
     4561 ctcgtttaca aatcggcttc ccagcaatct ttgcagaaaa aaacaagaga ttttgattct
     4621 tacaaataaa ccgcaagaag tccaattgct ttggcagcca aaagaaagag gatgccatga
     4681 aacattaact gtcattttta cagcctatga tagtctagga cttttcagaa aaagtgcaaa
     4741 aagagagatc tcttttcctg tgactgttct gcctgctttt tgtaagattc aagcagaaaa
     4801 attacagaga gttctggaaa aaaaacagca gctgaacgcg taccaaagag gtcttgattt
     4861 tcgggaacat cgcgcttatc gtccaggtga ttctttcaac cgaatcgatt ggaaattgtc
     4921 tgctcatact caagagtggt tataccgtga atacgattat caagaagaag aatgttctcc
     4981 tcttttttgc ttttggggtt cgcccagtcc aaaatttgaa cctctgctag acttgtattt
     5041 ttctttatgg catttgagaa aagaaaagca gccggaactt ctgatattag gcaaccgcgc
     5101 ctttcatggc aaagaccccg gtcataccta ttttgcttct ttggaagctg gcgatgagaa
     5161 aacttttttc gcacacttga aaaaatatgc aaaaaaacaa atcgtcctct ttgttcctga
     5221 gaattctcct gaagtctcag aagctattga aacattgtca aaagatcgaa cggtttatct
     5281 tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa gacaagatat gttcattgcc
     5341 aggaggtgaa tggattgacg attaaacggg aaaaatggct gcgtggcgtt tactcctttg
     5401 tgatactaag tgtaggtgct ccgatatttg tagtagctaa tcaattgcaa aacagctacc
     5461 ttcttatcct aactattggt gtcctatgcc ttattgtctg ctgtattcct aaaaaatggg
     5521 tacgtttgct gctttctttg ccagtaatga taggttgttt gtttttatat tttccttcga
     5581 agacattttc catattatgg atcttacagt ttttttcgtc agttacagag gaattcttcc
     5641 atctatccca aggtaaactt tattatttgc cagaaaagac agcttttttt ctcataatgt
     5701 tgctgatcta tttatttatt acattgaccg tggattacga ctattggtac gcaccctttc
     5761 tttctttgat ggcttacttc atgatgctta ccgtttttcg gaaaaaagat ttactgtacg
     5821 aaatgattgc ggtagtaact gttttgttcg tgtatctggc agcaaggcaa tttttctcca
     5881 tccggttgtt gtcgagaaac actcgattcc agtcattgac tacagttctg cttatttgtt
     5941 tcttaacttt tagcgctatc ttgcctttat atcttccgaa agtacaccaa tctctcgagg
     6001 aaacgagtga accgatccga gaatatctta atgatgaagg gctttatgac acactccatg
     6061 agtatcaatt aaccggaagt gcaagaacag gcttcagtga gaatgatgaa cagcttggtg
     6121 gacctttata tgataatggc gaagttgttt ttacagcgaa ccaaaaagga aatggctatt
     6181 ggaagatcga aaataaaaat cattacaccg gttctggatg aatagaagat caggacgcac
     6241 ccatccaacc aatccaagaa ttccctgttg acatcacgag ctaccaaacc gttatagaag
     6301 acaaagaaaa cattacattg accctaaaaa aacaagcttt cttaccttat ccttatggaa
     6361 atactacctt gactgatttt tcattagcta gtggacaaac gctttactat ttgcctgaaa
     6421 gccagcgatt cattcctgtc ccgaatgaat cgacacgttc tgcaacttta caaacagaaa
     6481 ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt aaaagctgat gatttagaaa
     6541 atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa acgtattgag gacttggcgg
     6601 tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt cgaagctgtc taacagtatt
     6661 taaaaacaag cggaaatttc cgctattcca aaacggatac cgggcatact ccaaaagaac
     6721 acgattatgt ggattatttc ctctttgatt caaaagtcgg ctattgtgac aacttttcaa
     6781 cttctatggt cgtccttctt cgaacacttg gtatcccagc tcgctggaca aaaggtttta
     6841 caaatgggct cagaacaggc acagataatc aagggaatga ggaatacagc attctcaata
     6901 gtcatgctca ttcttggcca gaggtatact ttcctggatt tggctggctt ccatttgaac
     6961 caaccccttc atttgccaat ccaatgggtt cacaaccagt tgctgaaaca accgaaaccg
     7021 tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat ggcagaaact atttccagtg
     7081 agagatctga ggtcattcca tcagaagaaa caacactcac accagcttat aaaatcgtct
     7141 tattcagcct tggagtgtgt ttatccgtct tgttgttctt tctattgtta ttcagaaaat
     7201 ctctgcgctg gacaagttat cttatctatc ttcatttttt tgcttctact aatacgattg
     7261 catatcaaaa acttcttaac cctttggaaa cattggtacc gcgcaaaccc gcagaatctt
     7321 tgcaggaata tagcctgcga atagaacaag aattcaagct agatctgcgt ttcattcgat
     7381 taactactca atatgaagca gaaatatatg gacgacaagc agatccggta aaattcgata
     7441 aaaaaaccta tttagaaata acgcatataa taagaaaaac ggtatacaaa aaaattctga
     7501 caaaagggag ccgcttcaaa aaataagata aaatttctgg agaatctact tctcgaatgc
     7561 cgagaaccag ctgattgagt atcgattact cgaaaaaaag gttgtgacac gttttttgtc
     7621 acaacctt
//
LOCUS       DAPBCF010000090         7609 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.093, whole genome shotgun sequence.
ACCESSION   DAPBCF010000090 DAPBCF010000000
VERSION     DAPBCF010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.093"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            1103..1621
                     /locus_tag="RD508_002673"
     CDS             1103..1621
                     /locus_tag="RD508_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HDT7737192.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            complement(2758..3165)
                     /locus_tag="RD508_002674"
     CDS             complement(2758..3165)
                     /locus_tag="RD508_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HDT7737193.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLVVYIATYDKDFDQLKYEVINTIKTHTKPI"
     gene            complement(3162..3395)
                     /locus_tag="RD508_002675"
     CDS             complement(3162..3395)
                     /locus_tag="RD508_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HDT7737194.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDVAISQALTEYDTTFRELVDK"
     gene            3728..4813
                     /gene="xerS"
                     /locus_tag="RD508_002676"
     CDS             3728..4813
                     /gene="xerS"
                     /locus_tag="RD508_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HDT7737195.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVTTITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKNTLSKRALIYYHRDVERDLAINALILGSGLRLSE
                     VVNINLDDLSLDKNKVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            5165..6055
                     /locus_tag="RD508_002677"
     CDS             5165..6055
                     /locus_tag="RD508_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737196.1"
                     /translation="MSENNYKKIGYNSLLNMSYEEAIHYLLNKYGEVSDDYFKEKSYA
                     RFLRGEIKTITKGKYSKTSEGLYCHHIYENKYENISSLYYINCFKYPFKYQKKESLVY
                     CDLFEHLILHALIIKETEAEYGLHGYEEYLYPIAIDWFLNETDPKPEWMKKCKERAYL
                     NQQDAEKIINKIHEIISPFKEARSAMLEEEYKKSIKKNIASKLGMTVSEYEEYLVQEE
                     KEAKKRLKLEELERLNEFNKKYPNLQKINVNNTTPRKKILNFLYELAYSKDFPKRKDF
                     YKAKISLIRDELLEELNDIL"
     gene            complement(6492..7046)
                     /locus_tag="RD508_002678"
     CDS             complement(6492..7046)
                     /locus_tag="RD508_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7737197.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQS
                     ITKRYIGITEDEIGASLKGFKLGI"
BASE COUNT         2726 a         1144 c         1149 g         2590 t
ORIGIN      
        1 tatcaagtac gctctgttcc caagaagctc ccacttcaag cgttaagaac cgtcaggttt
       61 agctaagtgg gggtagttca ctaaaacata taagttgaaa tgagcagcat ttttgataaa
      121 atagtactcg taaacgtcca tactatagac tttttaggta ctgtccgtta gtgaagtttc
      181 agaataagaa agtcataaaa atcgacaccg tgtcaaccaa cttaacagag tatcggtttt
      241 ctataattgt ttaaaaagaa gttatttttt tgccaacctt aaacaatcta taacaccagc
      301 ttgatccctt aattttggaa aaaaatttcg gaagattaac ataattattc ataattttag
      361 taaattcgcg gtgaattttc ttttgcaagt gtatctgttt cattacaccg caccctagaa
      421 gaatatctgg tgaaaacatc attgtagtat tataaatgca ttgtgcaaca taaaaagctt
      481 caatttccta aaaaggatga tcttcaggta aatcttgacc tttaatagtt cgtcgagcga
      541 ggcgtgaata tggcaatcgc ttttttagaa ttaaattttc ttcgagttgg tcatttcgtt
      601 tttgtagctg tttcatctga tgagccgtaa ggaacgtgtc atcgtcaatt tttacttcat
      661 aatatttttt acccaacgcg caatcgaaga aagagcgatg ctgtaatcct atataaagca
      721 ttttgagttt taccactttc gtgaagttta acaatggatt ttgtgaacta tcctcactta
      781 actaaactta acagttctta acgcttaaag tggtagtttt tattagtaat tgatagtagt
      841 taacatgatt ttgatattta cgaagaaaat gatatgcaaa ccagtccgat tttactacaa
      901 aagaaatata ttcgtatttt ttagctcctt gctgacgatc aacatttctt tagatgagac
      961 gttgggatat tttataaatc attcacatat gagttagaca gtcaatgcat atcagatatg
     1021 cattgtagaa cggattaaaa tatcgtggat gaaattatag atgaattaaa ggagacaatt
     1081 aggaatttat ggaggtaata taatgagaac atataaaaat aaagaagaat taaaaaaaga
     1141 aataaatagg acttatacta aatatatttt agaatttgaa actattcctg aagaattgaa
     1201 ggataaaaga gttgaggaag tggatagaac acctgctgaa aatttagcat atcaagttgg
     1261 ttggacgaat ttaattctaa aatgggaaaa tgatgaaaga aatggattat ctgttaaaac
     1321 gccttctgat caatttaaat ggaatcagtt aggagagtta tataagtggt ttacaaatac
     1381 ctatgcacat ctaccattga aagaattaga ggaaattctc aatcgtaata ttgatgatat
     1441 taacatgatg attgattcaa tgagtgatga agatctattc actgcacaca aaagaaaatg
     1501 ggcagacgag gcaaccaaaa cggctgtatg ggaagtatat aaatttattc atgtaaatac
     1561 agttgctcca tttgggactt ttagaacaaa gataagaaaa tggaagagat tagctttgta
     1621 aattcccgtt tactgctaag caattgtgga aaggagacct cttgtatgtt aacagtaaga
     1681 acatacgact acataagttc tttgctaact gccggttttt attgggtgaa tgcaagtgca
     1741 ctcccctaga atgccgtaga gggtgcatcg ttagattgta tcaattttgg ttggccaaca
     1801 gataaaccat gactcacttc gataaaatga gattatggtg ccatatccgc tgcaaaggga
     1861 cttaggagac tagcagggga aagatttttt tatttttggg atgtttttca gaccgccgat
     1921 agtaccgaca attcccttta aatatggaat ctcaacaacc cacatgaagg gtaaggcaag
     1981 tccggtaatt atatcttctg actttgggtt aggaagaatt gaaattgtta agaacgattc
     2041 aacgcttatg gtttataatt tggagatagc ctttgttaat atgctaaagc caacatacga
     2101 tacagatttt gagcagttta ttctaaccat caaagggtat gtggcctatc gcctatccta
     2161 ttactgatac tgaagagatc ttaaataaat tctatacggg atttgaagat cctgaaggtg
     2221 aaatcgtcat ttatcagaat aaataaatca aatagtagaa gttcaaagaa tgaggggaac
     2281 attagttttt attgcttagt ttaatcccag taacgatttc tgcaagatgt aaaaggtctt
     2341 tcatttcata agttttcaga agcaagttca tacgcgctaa ctcactttcg attgagtagc
     2401 aatcgtcaac aaactttact atcagctgtt atttttattc tttcgcgtta tctaaatacc
     2461 atcaatttat aagttgtagg tgtatttaat aaaagaacaa ataactttag tatttttatt
     2521 aatctaactt acaaactagt agtatagggg taaatttgcg attattcata aatataccaa
     2581 gtaaaagtat agggtatagt aaaaatatga taaaataaat agtcgttatc ttaatccaac
     2641 tatatagaaa atttacgttt tctatatact tggatttgga ttatagctat ttgtaattta
     2701 cttcaattat ttcgctatag cagctattaa cactataaag acacatacag caactcctta
     2761 aatgggtttc gtatgtgtct ttatagtgtt aatcacttca tattttagtt gatcaaaatc
     2821 cttatcatat gtggcaatat ataccactaa atttacagca tctttttgat caatagctaa
     2881 aagctgtcca ttgattttca aaaagacaaa agtagctaag aaagcagtac gtttatttgc
     2941 attatgaaaa ggatgtttct ttatcaattg tataagtaag atagctgctt tttcataaat
     3001 cgaaggataa acctcttctc caaaagctga ggctcgaagt tgccctacac acatttctaa
     3061 agcattcgca tcctttacac caaggggttc attaggagag tattttttta tttggattac
     3121 attcattttt ataatatctt tggcttctag gtaatgaata ctcatttatc gacaagctct
     3181 ctaaaagtag tatcatattc agttaatgct tgagatattg ctacatcaat ttcatcagat
     3241 aaggcttgtt tttttgtaat tgcggctcga agtttttctt catctaaaaa aaccgtatct
     3301 ccgggattta acccattttc tttaagaaat tcctttgaaa tagttaatac tactgagttc
     3361 cccacttccc taaattttct ttctttaatt gccatagtct tctccccctt tttctttgta
     3421 tatacagtat atacgcttgt tgattttaaa tcaagcatag cccctctcat gtctaactct
     3481 atagaaagat tgttctttct atataattaa ttaagaaaat tcaaaaaatt tagattgctc
     3541 ccttctattt ccttccctat ttatgtatac catttatttt aaattaataa acgtatacct
     3601 atttatatgc tttttttgaa acaaattaat aaattttaga gcataccaat tgacaaaaca
     3661 ttctataatt ggtatagtcc aattatagag atactcttct cccctactta ttgaaaggat
     3721 gaatgacatg aaaaatacag aaatatatca aaaaatagat acaatcatac ttcatatgcc
     3781 cgattatata aaagattttg ttcaagatcg tgaggataaa gatcaatcac ctcgaaccac
     3841 tttagaatat ctaaaaaatt ataagctctt ttatgaatgg cttctgagtg agtctatcgt
     3901 tcctgatact tctatcacct cgataagaca gttaactgcc tatgacctaa acttgtacaa
     3961 atctcatttg aaacgtcgca caaaagaaaa tgtaaaaaaa gagacaacaa aaactaagct
     4021 caaagataat aataacttag gtctatctac ttctactatc aatagaaaca tcacagcatt
     4081 aaaggttcta tttaaatatc tttcgaaaag ttctaataat cccctaggaa aaccatactt
     4141 agacaataat cctatggacc aagtaacaac catcacagat aaaactacgt tagctgcacg
     4201 tgccaatgcc attgagaaaa aattatttct agatgaggat acacaaaatt atctagatta
     4261 tattgccaat gaatataaaa atactttgag caaacgagct ttgatctact accatcgaga
     4321 tgtagaaaga gacctagcga tcaatgcact gattttagga tctggattga gactctccga
     4381 agttgtaaat attaacttgg atgatctatc tttggataag aataaggtgg tagtaactag
     4441 aaaaggaaat aagagagatg cggtcaatat agcagcattc gcaatggaat atttagctaa
     4501 ttatctagct attcggaaag aacgatataa agtgacagaa aacgaaaaag cattatttct
     4561 agcaatttac caaggagaag ccaaacgtat atccggtatt gcaatcgaac ggatggtagc
     4621 aaaatattcg aaaggattca gagtacaagt cagtccgcat aaactgcgtc atacattggc
     4681 tactagactc taccaacaga caaattcttt ggtattgact gcccaacaat tgggacattc
     4741 aagtacaaat acaacaactt tatatactca tatagataat gcagctacca ttgatgcatt
     4801 gaacgcttta tgagtataat atataaatag ccaaaatagt aaagtgagaa taatgaatga
     4861 aaccatgaat ccttttaacg taaatggatt catggttctt tttttgttgt aaccaataat
     4921 cttttgttaa taaatatgat taactattga gtaattcata ataaattata attactggca
     4981 agtagaggtg gtttatagga atattgataa cttcattgaa tttcaatata gagaaattga
     5041 aaattaaata agcgtataat attaagggat tatatgtttt ttgtaagtaa attccaactc
     5101 taaagtgata ggatatattt ctcatactct attcttaaaa tagtaaggag cttggtttat
     5161 aattatgtca gaaaacaatt ataaaaaaat aggttacaat tctttattaa atatgtctta
     5221 tgaagaagct attcattacc ttttaaataa atacggagag gtttctgatg actattttaa
     5281 agagaaatca tatgctagat ttttacgagg agaaataaaa acaataacta aaggaaaata
     5341 tagtaaaaca tcagaaggct tatactgtca tcatatatat gaaaataagt atgaaaatat
     5401 ctctagccta tactatatta attgttttaa atatccattt aaatatcaaa aaaaagaaag
     5461 ccttgtttat tgtgatttat ttgaacattt gattttacac gcattaatca tcaaagaaac
     5521 agaagctgaa tacggtttgc atggttatga agaatatctc tatcctatag ctatagattg
     5581 gtttcttaat gaaacagatc ctaaaccaga atggatgaaa aaatgtaaag aacgtgctta
     5641 tttaaatcag caggatgctg aaaaaattat aaataaaatt cacgaaatta taagtccctt
     5701 taaagaagcc cgttccgcta tgttagagga agagtacaaa aaaagcatta aaaaaaatat
     5761 tgcgtctaaa ttaggtatga ctgtttccga atatgaagaa tatttagtac aagaagaaaa
     5821 ggaagcaaaa aaacgactta aacttgagga attggaaaga ctaaatgaat tcaataaaaa
     5881 atatcctaat ttgcaaaaga taaatgtcaa taatacaacc cctcgaaaaa aaatcctaaa
     5941 ctttttatac gaattagctt acagtaaaga ctttcccaaa agaaaagact tttataaagc
     6001 aaagatttca cttattaggg atgaactatt agaagagcta aacgatatac tttaaaaatg
     6061 tttatttctg gaactttatt agaaataatt ttgaattttt gagtgagttt gtttttcatt
     6121 attttctcct gataccataa taactctcaa tagtttgtag gaaatactct tcaatttaat
     6181 tactttaata attagttcga tcaatcattg taatatttta ttgattcgaa ctgtggtatt
     6241 tattaagtta gtttattgca tggtttttat atttcatatc acgagctata attctatttc
     6301 tattatccta tttagatttt gaagaactaa aatgtttttg ttgattcata cagaccattt
     6361 tgaaaattcc aagattttta agaagtccaa ctaacttaaa aaaccttcaa gaatatcttg
     6421 gaggtttttt atttttttcg aaataggaga atcgattcaa tatattaatt tttgttacaa
     6481 gcaggtactt actaaatacc taatttaaag ccttttaaag aagcgccaat ttcgtcttct
     6541 gttattccaa tgtatctttt agtaatcgat tgagaactat gattaaaaat aaacattaag
     6601 gtagcaatgt ctctagtttt cttgtagtag tgatacccaa aagtttttct taatgtatgt
     6661 gttcctatat catctcttcc taatttttct gctatatctg catatatctg atagacacga
     6721 tcccttgtta tatgtcgacc ttgttgccga cttggaaata accaatcatt ttcttcttta
     6781 ccttcagtat ataataaaat ctcttctctc aaattatcta taaaaatcgg ttttcgctta
     6841 cctgttttat gttcaacaat aataggctta cttttacctc gtatatctcc aacttttaat
     6901 cctataatat ctgacatacg taatccatta ttgatgccaa acaaaaataa aaaactatct
     6961 ctttccggat tacttgttct tcttagccaa aactgaaaat cttgtatctc ttcatttgtc
     7021 cttaacggtt gtacattata gctcactatt gtttcccttc ttaaaaatat tctgagttta
     7081 tgattatgta tatattttac cataatcatg aacttatata tatactatgt taaaagtcaa
     7141 gaaaatcaag gggttcagtt tatgatttta tatcatttca gtaactcaga atattccgac
     7201 ttttttgtac aaaaaaatta accttactta tatgaagatt ctaacctctt atttaaattt
     7261 tagacgggca attatccgta gaagttctta gaatagctaa tttacataat taaattatat
     7321 gaaatttaag tttgaacaat atactaagaa ctccccttac tataaagtga aataaattag
     7381 catatgaata accgtgctac caagcttttc attaataaaa tatttttatt gatattttat
     7441 aactttacgc aagatcataa ttttgtctgt gtagatattt cgttatatca ctaaagataa
     7501 taagatttaa tgacctcatt aatattgttt gctagatcca aactcttatt aaactttcct
     7561 tgctataaaa cccaaacata gtaataaaag aataacttat tacctttaa
//
LOCUS       DAPBCF010000091         7600 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.094, whole genome shotgun sequence.
ACCESSION   DAPBCF010000091 DAPBCF010000000
VERSION     DAPBCF010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.094"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(943..1356)
                     /locus_tag="RD508_002679"
     CDS             complement(943..1356)
                     /locus_tag="RD508_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HDT7737198.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="RD508_002680"
     CDS             complement(1812..2297)
                     /locus_tag="RD508_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737199.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="RD508_002681"
     CDS             complement(2436..2651)
                     /locus_tag="RD508_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HDT7737200.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="RD508_002682"
     CDS             2875..3675
                     /locus_tag="RD508_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7737201.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="RD508_002683"
     CDS             3694..5562
                     /locus_tag="RD508_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDT7737202.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="RD508_002684"
     CDS             5555..6046
                     /locus_tag="RD508_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HDT7737203.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /gene="srlA"
                     /locus_tag="RD508_002685"
     CDS             6034..6588
                     /gene="srlA"
                     /locus_tag="RD508_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDT7737204.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..>7600
                     /locus_tag="RD508_002686"
     CDS             6606..>7600
                     /locus_tag="RD508_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDT7737205.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2237 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg
//
LOCUS       DAPBCF010000092         7370 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.095, whole genome shotgun sequence.
ACCESSION   DAPBCF010000092 DAPBCF010000000
VERSION     DAPBCF010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7370
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.095"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(200..1084)
                     /locus_tag="RD508_002687"
     CDS             complement(200..1084)
                     /locus_tag="RD508_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HDT7737206.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEADGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(1179..1616)
                     /locus_tag="RD508_002688"
     CDS             complement(1179..1616)
                     /locus_tag="RD508_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737207.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(1833..2744)
                     /locus_tag="RD508_002689"
     CDS             complement(1833..2744)
                     /locus_tag="RD508_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDT7737208.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(3121..3759)
                     /locus_tag="RD508_002690"
     CDS             complement(3121..3759)
                     /locus_tag="RD508_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7737209.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(3763..5745)
                     /locus_tag="RD508_002691"
     CDS             complement(3763..5745)
                     /locus_tag="RD508_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HDT7737210.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFILLFVERFNQAFHTDYATNIFE
                     DFENSYSYSVISSTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNGFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHETPKEIAGED
                     YQVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSTYWERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            5925..6587
                     /locus_tag="RD508_002692"
     CDS             5925..6587
                     /locus_tag="RD508_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7737211.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALRIAHNLV
                     KF"
     gene            complement(7068..>7370)
                     /locus_tag="RD508_002693"
     CDS             complement(7068..>7370)
                     /locus_tag="RD508_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7737212.1"
                     /translation="LGVKGQNLLADDSFWQIEAFYLAQCAYNTTLMLSPDRIIFGGGV
                     MKQEHMKKKVQDKFVELINGYVEIPPIASYIVTPELGDSAGIIGGLALARKAIRNK"
BASE COUNT         2353 a         1391 c         1115 g         2511 t
ORIGIN      
        1 aaggaacttt gagatattct ttaggatatt aaaattaact agcaccacgg gtttaaaata
       61 tgtattttta tggcaaattt ttctgttagg tgaaaatttc ttttttgtac aaaaaaaggc
      121 tgtgacaaaa gtcttgtcac agtcccttat tccgaacaac cgatgtcctc ctgacaactc
      181 ttcggtcaca acctccattt taacaataaa cctgtaaatg tgagggtaac actttgattg
      241 tcacaggtaa tttatcccct tcatctccat caacattcgt cgtcaattct tcctcatcag
      301 ctaatgacac aactaattgc tcacaagtaa gataggctag atttttcgta gattcatcta
      361 ctccttttaa taggtctggc aatgttttaa gcgtatcgat caaagaagaa tcttttaaat
      421 aaaccaaatg gagcttacca tcatccactt ttgcatttgg aagtaatgtt tcaaaaccgc
      481 ctactgagtt agttagtcct atcagcaaga tactgctctc aatttcttcc ttctttccat
      541 cagcttctac gtgaaacgag taggattgtg tggaagctaa ctgtttgatt cctgacatga
      601 aataagctag ttttccaaat ttcgtcttct tctccgcatc tacatcattg attgcttcag
      661 ggatagagcc aattgcgacg acattcataa aatagtcgtc atttattttt ccaatatcca
      721 atggcttgac tgattcaatc gaaaaatgat tgatcgcttc ctcaggttct agcggtatcc
      781 ctaatgctcg agccaagtca ttcaccgtac ccaatgggaa aaatccgaaa tttggccgat
      841 gttcttgttc agcgattcca ctgattcctt cgttgactgt tccatctccg cccatgacaa
      901 acacactatg atacccttcc gtagccgctt cgcgagtaaa gttttttgca tcccctgctt
      961 tttttgtatg caagacgacc acttcatcaa acaccgattc caattttgct atcgctaatt
     1021 gctcaaattc ctttgcttgt tcaccgcctg aactggggtt taccactaat aaaacttttt
     1081 tcatcacttt ctttcccttc tgattgattt ctttaatata acgatagcat aaagaaaaaa
     1141 attaggctgt gatgaagtac tgttcatgaa acattcattt attttttgac aagataaaat
     1201 acccatacta tgaaactgag gaaaattaaa acaatgatat aggaaataaa agaaaatgat
     1261 aggcattgta tacctaataa agtaaaaatc ttaggtggca gataaaaaca caaaaatagc
     1321 aagagaatgt aatagcgttt cttccacttt ttgttatcag accttatagc gatcagagga
     1381 ataccaaatg cataactgaa aaactcttga tgtactgtta atatgtcacg accttgaata
     1441 ataaatgcaa caatccccgc tataattagt gtgcctaata ccaaaacgga aaattgatga
     1501 atatatttta tatacaaatg atccattgta cttcctgcct ttttatttgt gagaaaaaca
     1561 aatccgtata cgtgaataac ttctagaaat aaaagaaatt tgcaaaacca ctccatttat
     1621 ctacttctac gtgcattttt taatatcgtt ttctttattt aagattatac agaaaaatat
     1681 ctagggtggc tggattctaa gtaaaaaaaa tttttaaaat aaaaagaact aaatcaagta
     1741 ataattaaac tactgttgat ttagttctaa taaaaagatt tagatgaaca gttttattga
     1801 tttaaatagt tcatattttt tatttatacc gcttatttac tacttgctgt actagaatct
     1861 gaagtgaatg tactcaaaac attttcaaag tctttgtctt tgatttttac attagcgtct
     1921 ttcaatactt cgccaattac tttattctgg aaggtactgt cacttaattt tgtgtctgtt
     1981 gcaatttctt tcaattcttt tttgtattta tccatgtcgt tgcctttgtt ttggtttttc
     2041 accattttaa ccacataata ttccgtagta taagttgaag cattggtaga agtgatcaca
     2101 tcagaaactt gaccatcttt caacttaaag gctgcttctt tgacttctgc cggaaccgtt
     2161 gtagtagtgg aatcaaattt cacttttccg ccatcttctt ttgtcgtagt atcagttgac
     2221 ttgtctttgg ctaatttaga gaaatcgtct cccttatcag cagctttctt cacatctttt
     2281 gcatcatctt cacttgctac ttggataatt tgagcttcca cttctggatg gaaagattcc
     2341 caagccgttt ttaaatcttc atcggtcaat ttgatatgtt tctttagacc ttcttgaaag
     2401 gctagacttt gtttgatact gtctttgaat gtttgttctg tgtaacctgc agatttcaat
     2461 tgtgaatcaa atgaatcacc caattgtttc tttgtttgat catattggga atcgatttct
     2521 ttggttgata cgtcatctcc atatttatct tcaaatactt gataaacgat caactgttgc
     2581 acagcggaat ctgctccttg catttttttc aagctatcca ttacttcttg ttcgctgatt
     2641 gtaccgcctt tataactaac ggctgttttt tcaccggcat tcgtacagcc tgacaataag
     2701 ccagtgccta gtacgatggc aagtgctaaa aatctttttt tcatttatca attctcctac
     2761 ttttcgtttt ttgcgaattg ctaaaaacaa aggtgttcaa gatgaaaatc atcaagaaca
     2821 cctttactaa tctgctcgat acgtcctgaa tagatataag gctacacaat ccagaaagtt
     2881 cgctcagcag aataaatgtc aagtagcaca tcacacctta atatactact tcttttgtta
     2941 ccgtttttca agtctatctt gcgttccgta tttaacgtaa ctaattctta gaacaaatgt
     3001 tatcgatttt gtttttcttc ttccgctgtt gggatattca aatcagacac ttttatgttc
     3061 gattttccag acattttttt gttgttttta ttagaaaaag tttgtttttt catttgtttt
     3121 ctaaagcatg atcttcttgt ttcctatttt ggtcagatat ggatcatgcg tgaccacgat
     3181 aactaacgta ccttgggaag cctgttgcga taagatttca acgacttgct ccttatttcg
     3241 tttatctaat gatccagttg gttcatcggc taaaatgatt ttgctattct tcaataagac
     3301 tctcgcacag gcgattcttt gcttctcacc accagataat gtgtagatag gcgtacttag
     3361 cttcttgttt atatttactt ttttcaatgc ctcatacttt gctgttcgct tatctgaaac
     3421 atttaaattc gaaaacttca atccaatatc taaattaaaa tcgattgttt catattcaat
     3481 caacccaaaa tcttgaaaaa gaaaagagag ggcatttctt tttatcaagc gcttctctct
     3541 tccagttaaa tgttttgttt cttgattaaa taaataaaat tgccctgaac tgaattgatc
     3601 attcaatcct aatatattca ataaagtact tttccctgct ccgctctctc caactacagt
     3661 cacaaaatcc ccagcatccg cagtgaaacg atccaaatga agaatcgttt tgtttcgaat
     3721 gatttttttc gcacctttta tcactatcaa cggctccaat tgttaacctc cattcatcag
     3781 caataactga cttttctttt ctgtagacaa aataaaaaca actgaaagaa taaaatcaat
     3841 gaagctaaag aaaaaaatat taaaaagata tttaggctct ctttctataa gaaaaaggaa
     3901 gattacactt gtcgttcccc atttgatgag gttcatcatg aagaaatctt tatacgtttc
     3961 aaagagcgaa taaccacttg aacgaaagat agcgattttc cgacaattgt agacaaaata
     4021 tatgcataac atgacatagc tcaacaagaa gaaagaaaag aaagtgagta aaaatatctg
     4081 tatcaagtaa tgaaatgatc tgcttaacac tttgacagct atctcttcag tctgagtata
     4141 cggaaatgat aactgcaagt tatcacgtaa ctgactttct tcaatcagct caaataacct
     4201 ttctttcgac aaagagccta tcttgatctt taacggtgga tagatttctc cgctgagaat
     4261 atttctttcc caatacgtac tgtttttcaa tgtcagtatt tcaacaaccg gataatgttc
     4321 gatccagggg atagaaggaa taaatgtata aatgggttga ttgtttttta taaatagaaa
     4381 tttcggttct ttttcactga tttcttgata atattctgtt atttgcgcca ggtcattttt
     4441 taaatctgta tgtctatatc gttcagggat caatataaca gggtgcgttt ctttttcggt
     4501 tatttggatc aaccttccag agacatcaat caaaggaaat ttcttaagat aattcagatt
     4561 tatttttatc cctctgccaa actgttcatt ttcttcattc aagtaatctg atacattgac
     4621 taatatactt ccgtttttat tcaaagtttc atataattcc tgatcggctg ctgatgcaaa
     4681 acgattggaa taaataaaat ccacgtggtt tttcccgatg gttactggat aaaatacctg
     4741 atagtcctca ccagcgattt cttttggtgt ttcatgggaa acagctaact gtgaagaaga
     4801 aaaaacgata gttgctaatt cgacattggc aacggtcaaa agaagagaaa acaacaatcc
     4861 aaatgtaaaa agaatgtatt ggatatagtt gaacgcttct cttaacgaag cgattttttc
     4921 aactaataaa agagaaatca aagagatacc atatattccg ctgaacaaga aaacgtacat
     4981 ctggaacaaa taaagaaatt gctccttata atacataaaa ataaaaccac caatgattcc
     5041 tgcaattatg aatgtaataa tgattttctt tttccccaat aaacaccaca atacttgatg
     5101 taatgaaaag ccattattca acaataaact gatttcttta ttcatcaata agaaaaagga
     5161 tgataacaaa aggaataaaa gaatcaatcc aatagttaaa tacactcgat aattatatac
     5221 gtctgtactt gaaataaccg aatacgaata gctattttca aagtcttcaa aaatattagt
     5281 ggcataatca gtgtgaaatg cttgattgaa tcgttccaca aatagtaaaa tgaaccgttc
     5341 ataggcttct ttttctctcg tcatcaagaa aaattcacct tcaaaatctt ttattttgat
     5401 cgattcttca atggacgtta cgcgaaagga ggtattagaa tagggtacct tctcgtgaga
     5461 agatttgaca tccccttgat aatacaatgt catttcaagc tttggctgta tcttgaagtt
     5521 ccaagatgta tctacttcat tggattcatt tactgttttt ttcatataag aaagctcagt
     5581 ttctgatgag acattttcaa ataccatgat tagctgctca tattcttctt gcccaataaa
     5641 atgttgtggc aatcgaatcg gagtataagt atctgtttga tggaaaaatt catttgtccg
     5701 atagagtacc tgtttattta tactaaccaa ggcaaaacca ctcatgatac cggtcactat
     5761 gattgtgagt aaaactgtga actttttttt gattatcacc actctccctt acttaaatga
     5821 ttctttgata aaatcatacc gtttttcatc aaaaaaacgt atctatcaaa tgtataggtc
     5881 atgtagaata aatctatata ctgtagaatc gaaaggagaa gaagatgaac atcggagaaa
     5941 aaatacgaac ttaccgcaga aattgtaagc ttacgcaaaa agaattaggc gaaaaaatcg
     6001 gtgtttccga taaaacaatc tctagttggg aaaattctcg tacaatgcca gaccttgaaa
     6061 tgctgtcact tttacatcag actttaggtc tgccgattga ttttccttct attgaatcag
     6121 ctaccgaatc aatagaacca acattgccgg atgaacctct tgttatcaag aaatcttatt
     6181 catcaaaaca acccttctca ctcaaaaaga cactatcttt ctttctgctc gtcttttgtt
     6241 tggtctatct ttttcttatc aattatcaat ataaaaatga aacggttgat cgattcaatc
     6301 cttttttgaa accacaaatc ggctatacca cactccctgt aggatacgtg gaaaattcca
     6361 tcgaacattg ggtatgtaat gatatctttg ttcatggtac atggctgtct tttcacgctg
     6421 gagaggtaga aaaaggtaag aatcatgctg taatcaaaca caaaggaaaa cacgtcatga
     6481 acgttcgcct gctcacttgg gaagccattc cctcagatta ccaagaaatc ctcatccaag
     6541 actatgacga tgccttaaga atagcacata atttagttaa attttagttc ttttttatat
     6601 ttctacagcc tgttaataag taaaatttta cttttgtata atgatttacc ccacagatcc
     6661 ttccatatag attttcaaat tacacactag tttaagataa aacaaacaag gaaaaactta
     6721 ccatttactc aaaaaattaa ctcatataag tacattagaa tgtaaaatag actggtcaaa
     6781 atctggtcaa aaaagtagat gtgacacaag ttcgcattca aagcgatgat ccatgatttc
     6841 gtaatggtca attatatgga tcaaagccac gcgacaagag cgcaatggat gtctctaccg
     6901 attggttgaa taaacgaaat aaatagaatg tgaaaaagga tcggacaaat gttccagttt
     6961 gctcgatcct tttttatttg aattcatttt cgctttatca aacatcattt gattactcag
     7021 ttaaatactt ttgacatgag taccaatgaa acatttattc attaaaatta cttatttctt
     7081 atcgcctttc tagccaatgc caatccgccg attattccag cactatcacc taattcgggc
     7141 gtaacaatgt agctagcaat tggtggtatt tcaacatatc catttataag ctcaacaaat
     7201 ttatcctgaa cttttttctt catgtgttct tgtttcatta caccaccgcc aaaaataatt
     7261 ctatctggcg aaagcatcag tgttgtattg tatgcacatt gggcaaggta aaaggcttca
     7321 atctgccaaa acgaatcgtc agccaataaa ttctggcctt ttacacccaa
//
LOCUS       DAPBCF010000093         7367 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.096, whole genome shotgun sequence.
ACCESSION   DAPBCF010000093 DAPBCF010000000
VERSION     DAPBCF010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.096"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(99..1229)
                     /locus_tag="RD508_002694"
     CDS             complement(99..1229)
                     /locus_tag="RD508_002694"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HDT7737213.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="RD508_002695"
     CDS             complement(1878..3080)
                     /locus_tag="RD508_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7737214.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="RD508_002696"
     CDS             complement(3140..3343)
                     /locus_tag="RD508_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HDT7737215.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="RD508_002697"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="RD508_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="RD508_002698"
     CDS             4880..5692
                     /locus_tag="RD508_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7737216.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6868)
                     /locus_tag="RD508_002699"
     CDS             complement(6716..6868)
                     /locus_tag="RD508_002699"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDT7737217.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7059..>7367)
                     /locus_tag="RD508_002700"
     CDS             complement(7059..>7367)
                     /locus_tag="RD508_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7737218.1"
                     /translation="LGVKGQNLLADDSFWQIEAFYLAQCAYNTTLMFSPDRIIFGGGV
                     MKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGIIGGLALARKAVRNKQP
                     "
BASE COUNT         2268 a         1477 c         1133 g         2489 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaa
//
LOCUS       DAPBCF010000094         7195 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.097, whole genome shotgun sequence.
ACCESSION   DAPBCF010000094 DAPBCF010000000
VERSION     DAPBCF010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.097"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            445..855
                     /locus_tag="RD508_002701"
     CDS             445..855
                     /locus_tag="RD508_002701"
                     /inference="COORDINATES: protein motif:HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDT7737219.1"
                     /translation="MYTIILASHKNLAKGMKETVEYILGPAPFIKVMTAYTDDNYDIE
                     KDTNILLDGTDKVLVITDLLGGSVNNHWMNYVYEKKLTKKITVIAGMTLSLIMELSMN
                     IEDYKLREKISMIIAESQKSIINCSELMEVEDND"
     gene            848..1303
                     /locus_tag="RD508_002702"
     CDS             848..1303
                     /locus_tag="RD508_002702"
                     /inference="COORDINATES: protein motif:HMM:NF015769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7737220.1"
                     /translation="MIKLLRIDDRLIHGQVAMAWTKSVSADYIIVVDDASANDKMKQM
                     ILSLAKPVSTGLDIITSADFLSTFEKRKNQNLMIVTSSPKSAFEIVNAIPGEVDSINI
                     GGLRYAEGKEKVNEYVAITSEDKNYLAKLKESGFKLIMQATPTGKAKIY"
     gene            1320..2051
                     /locus_tag="RD508_002703"
     CDS             1320..2051
                     /locus_tag="RD508_002703"
                     /inference="COORDINATES: protein motif:HMM:NF015566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7737221.1"
                     /translation="MIECILIGIVGYLTTIDERYFGASMMNRPIIVGPVVGLILGDLH
                     QGILIGAALEAMFIGIVTIGAALPPDVGVAGTIATALAIKSGAGADVAVTLAMPFAVL
                     AQGLNMLAFTINSFTVSQGRKAIENRKLSSFQKWHFFPLIVRLPSAVLTFLVVYFGAN
                     ATESFVNIMPEKLMTGFTVASGLLPAVGFAMLIQGMIDKKSVPYFFIGYLLAAYLGVP
                     VVGVAVAAIMVALLVIQTKRNPVNI"
     gene            2068..2880
                     /locus_tag="RD508_002704"
     CDS             2068..2880
                     /locus_tag="RD508_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017867010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7737222.1"
                     /translation="MGDSKLTKKEINKVFWRSFALQGSESYTDMQGMGYSFSILPALN
                     KIYQGNDEKYYEAVYRNTEFFNTTPHISTFIMGMSLALEEENAKTDQFETETISSIKA
                     ALMGPVAGIGDSFYWGTFRVIAAGIGLSLAAQGNILGPILYFSIYTLLHFLGRYGCLR
                     IGYRMGANAIEKAFENNYLESFSLAASIVGLMSIGAMTSSLVRFTIPAVFKSKGGEIN
                     VQQMLDDIFPGILSLGLTFFVYFLLKKKVKVLWIILAIFVFSIVGVYIGLLG"
     gene            complement(3096..4379)
                     /locus_tag="RD508_002705"
                     /pseudo
     CDS             complement(3096..4379)
                     /locus_tag="RD508_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(4454..5865)
                     /locus_tag="RD508_002706"
     CDS             complement(join(4454..5310,5310..5865))
                     /locus_tag="RD508_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDT7737223.1"
                     /translation="MAKYPFELKLKIVKEYLSGVGEYRHLANKYGISSKSQVSDWVNA
                     YREYGEEGLLKKHQNQKYSVQFKLNALELYQTSEMSYREVASTLEMNNPALIANWMRN
                     FREAGIEGLSKEKGRPLTLTRKKENKKENTTTEERERIKALEKQVRSLQIENAFLKEL
                     RKLRKQEAQQRRKNQSHESSPASEDPFKLVELLETLKFPKATYMYWQKRFDRPNPDQE
                     IEEKMLEIRKEHKDYGCLRLKKELENQGIHVNKKKIQRLIKKLGIEVKSYTRKSRRYN
                     SYHGKVGTVAKNRIHRRFYTNICHQKITTDTTEFKYYEVDTTGVVRQKKLYLDPFMDF
                     YNSEILSYRISEKPNALAIMEGLEEAIQMTNDCPFRRTFHSDQGWAYQMNAYKNKLKQ
                     HKIFQSMSRKGNCLDNSPMENFFGLLKQEIFHGEVYRSLDELKTKIDQYIYYYNHKRI
                     KKKLNWRSPVQFREAVKTAV"
     gene            complement(5846..6037)
                     /locus_tag="RD508_002707"
     CDS             complement(5846..6037)
                     /locus_tag="RD508_002707"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737224.1"
                     /translation="MGKYSFEFKSTIVQEYLEGEGGLGYLAKIQGVRSKKGTRMDQSK
                     VRPKNLTFGGRYLYGKISF"
     gene            6554..6782
                     /locus_tag="RD508_002708"
                     /pseudo
     CDS             6554..6782
                     /locus_tag="RD508_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            6893..>7195
                     /locus_tag="RD508_002709"
     CDS             6893..>7195
                     /locus_tag="RD508_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7737225.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYARSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEK"
BASE COUNT         2189 a         1277 c         1254 g         2475 t
ORIGIN      
        1 tatagataaa ttattttctt taaacttata ctcattttta gatattttat aagaatactt
       61 catgtcttcg ccagtaatat aaagaacatc tgtctctcca tttggacttg ggttatctat
      121 tttgggtgta acatactata catacaaccg atacataaaa gatttgacat ctggacaaaa
      181 cacaatgctt tacttcattt ttataggctt tgtttacacc atcacaaaaa tcacctccta
      241 atttacaaat tcattaaaca aacagaaata aaaaatcacc acgatagccg cgttcaaaaa
      301 aatttacaaa agagaatttt agttaaagtt tttagattcg ccccactaat taccaaaggt
      361 attttattta ttcttaatac gaaataattt attgacattt agattaccaa tggtatatta
      421 tttataaata aatggaggtg gattatgtac acaattattc ttgcaagcca caaaaattta
      481 gcgaaaggaa tgaaagagac agtcgaatat atccttggcc ctgcaccatt cataaaagta
      541 atgactgcat acacagacga taactatgat attgaaaaag atacgaatat tcttctcgat
      601 ggaactgata aagtccttgt catcactgat ttacttggtg gtagcgtaaa taatcattgg
      661 atgaattatg tttacgaaaa aaaattaaca aaaaaaatta cagtaattgc aggtatgact
      721 ttgtccttaa ttatggaatt aagtatgaac attgaagatt ataaattgag agaaaaaatt
      781 tccatgatta ttgctgaaag ccaaaagagc attataaact gttcagaatt aatggaggta
      841 gaagataatg attaaactat taagaattga cgatcgcctg atccacggtc aagttgcaat
      901 ggcttggact aagtccgtat ctgctgacta cattattgta gttgatgacg cctctgctaa
      961 tgacaaaatg aaacaaatga ttttatcatt agcaaaacct gtatcaacgg gactagatat
     1021 tattacttca gcagattttt taagtacctt tgaaaaaagg aaaaatcaaa atttgatgat
     1081 agtcactagt tcccctaaaa gcgcatttga aattgtaaac gctatcccag gggaagtcga
     1141 ttcaattaat atcggtggtt tacggtacgc cgagggaaaa gagaaagtta acgagtatgt
     1201 ggctatcaca tcagaagaca aaaactactt agcaaaatta aaggagtccg gcttcaaatt
     1261 aattatgcag gctactccaa ctggaaaagc gaagatttat tagaaggtgg ggaataagaa
     1321 tgattgaatg cattttaatt ggcatagttg ggtatttaac gacaatagat gaaagatatt
     1381 ttggggcatc tatgatgaat cgaccgataa tagttggacc tgttgttgga cttatcttag
     1441 gggatctcca tcaaggcatc ttgataggag cagcattaga agcaatgttt attggcattg
     1501 taacgattgg tgctgcacta ccaccagatg taggtgtagc tggtactatt gcaacggctc
     1561 tagcaataaa aagtggagca ggtgctgatg tagctgttac attggcgatg cctttcgctg
     1621 tattggcaca aggattaaac atgttggctt ttacgattaa ctcctttacc gtttcacaag
     1681 gtagaaaagc aattgaaaac cgcaaattat catcttttca gaagtggcat ttttttccat
     1741 taatcgttcg cttaccttcc gcagtactta catttttagt agtatatttt ggtgccaatg
     1801 ctacagaaag ttttgtaaat attatgccag aaaaattaat gaccggtttc accgtagctt
     1861 ctggtttact ccccgctgtt ggatttgcca tgctaattca aggaatgatt gacaaaaaat
     1921 cagttcctta ttttttcatt ggataccttt tagcggcata tttaggagtc cccgtagttg
     1981 gtgtagctgt tgctgcaatt atggttgctt tattagttat ccaaactaaa cgcaatcctg
     2041 taaatattta aagggagagt gataattatg ggagattcta aattaactaa aaaagaaata
     2101 aacaaggttt tctggcgttc atttgcttta cagggatccg agtcatacac tgatatgcaa
     2161 ggaatgggat atagtttttc tatattacct gctttaaaca aaatatatca agggaatgat
     2221 gaaaaatatt atgaagctgt ttaccgaaat acggaatttt ttaatacaac gcctcatatt
     2281 tcaaccttta ttatgggtat gtcattagca cttgaagaag aaaatgcaaa aacagatcaa
     2341 tttgaaactg aaacaatttc atcgataaaa gctgcattga tggggcctgt agctggtatt
     2401 ggtgatagtt tttactgggg aacatttcgc gttattgctg ctggcatcgg cttatcttta
     2461 gctgcccaag gaaacatttt aggtccaata ttgtattttt caatttatac gctgttacat
     2521 tttcttggca gatatggctg cttacgtatt ggatatcgga tgggagcaaa cgccattgaa
     2581 aaagcatttg agaacaatta ccttgaaagt ttctcgttag cagcatctat cgtaggttta
     2641 atgtcaattg gagccatgac ctcatctctg gtacgcttta ctattcccgc cgtatttaaa
     2701 tcaaaaggtg gagaaataaa tgttcagcaa atgctcgatg atatttttcc aggaattctc
     2761 tcattggggc taacattctt tgtttacttt ctattaaaga aaaaagtaaa ggttctttgg
     2821 attatacttg ctatcttcgt ctttagtatt gttggagttt atattggatt attaggttaa
     2881 ttaatccaga ataaaactag atcagacatc aacttaaacc ataaaatacc caaagataaa
     2941 tgtaaatatg agtaaaaaga gcatggtata aattattagg atctataatt tatgggtctg
     3001 atgaatcaga attgattctg tagtgaccta aaaaagatag atgttttcgg agtggagaaa
     3061 attcactccg tttttctttg cttttcttga tgattttaga cagctttgaa tgctattact
     3121 ctaaattgca ccagactctg ccagtttagt ttccttttca tacgctcatg gttgtagtaa
     3181 tgaatataac catcaatggc ttgcttcaat tcttcaaaga tacgatagtc tcttccataa
     3241 taaatttcct gctttaatag actaaggaag ttctcaatga tcgaattatc taagcaggtc
     3301 tccttacggg acatactttg gaagatctta tgttctttca acttatgact ataagctttc
     3361 atttggtagg tccatccttt ttggagtgaa aagttcgacg atagatacat tccgttgcgc
     3421 agatagcttc ctctaaagct tccatgatag ccaacgcact tggcttctca gaaatgcgat
     3481 aaaataaaat ttcactgttg tacatatcta aaaatggatc aagatacagc ttcttttcac
     3541 gattggcacc gtatttatcc atttcaaaat attttagttc tgtcgtatct gttgtaacct
     3601 tttgatgaca gttgcttgtg taaaagcgtc gatgaattcg attttttgta atcatgccga
     3661 ttcttccacg ataagtatta tagcggcgat attttctcgt aaatgatcgt acttcaatac
     3721 tcagctttcg aatcaaacgt tgtacttttt tcttgttaac atggaaccca cggtcccaca
     3781 attcctttgt catacgtaaa tagccataat ctttatattg acttcttatt ttaagcattt
     3841 cctcttcgat ttcttgatct gaatttcttc gatcaaatcg tctttgccaa tacataaagg
     3901 ttaattcagg aaatttcaag gtttcaagaa gctcaactaa tttgaatgat cctcggaggt
     3961 tgtcgatgat tcgtgcgatt gattcgttcg tctttgttag acttcctgtt ttctaagctt
     4021 cctcaattct tttaaaaagg tattctcaat ctgaaggaaa cgcacttatt tttccaattc
     4081 tttgatacga ttatgctctt taggcgtcag tttgcttgtt tcttcctttt attctttctt
     4141 agacaaaatg gaggaggacc ctttcatttt tgagagcccg tgcaatcctt ttgaacaaaa
     4201 attttcatcc aattgacaac taacgcaggt tggtttatcc ctaaatgatt cgccacttca
     4261 cgataggata gctcacccgt tttttataac tctatcgcat ctatcttgaa ttgaacagaa
     4321 taacttcgct tatttcgctt acgcaagagg ccttcttctc caaattctcg ataagcattt
     4381 gtagcgaccc caaaaagtta gacttttatg gagtggagaa atccactcct tttttgtacg
     4441 ataaaattaa ctgttagaca gctgttttta cagcttctcg aaactgaacc ggacttcgcc
     4501 aatttaattt ctttttgatg cgtttatggt tgtaataata gatatattgg tcaatttttg
     4561 ttttcaattc atctaaactc cgatagactt ctccatgaaa aatctcttgc tttaataaac
     4621 caaagaagtt ttccataggt gagttatcta aacaattccc tttacgagac atactctgga
     4681 agattttatg ctgcttcaat ttattcttat aagcattcat ttgataggcc catccttgat
     4741 ctgaatggaa ggttctacga aatggacaat catttgtcat ctggattgct tcttctaatc
     4801 cttccattat ggctagtgcg tttggttttt cagaaatccg ataagataga atttcactat
     4861 tgtagaaatc catgaaagga tctaaataca gctttttctg acgaacgaca cctgtggtgt
     4921 ctacttcata atacttaaac tctgtggtat cagttgtaat tttttggtga cagatatttg
     4981 tataaaaccg acgatgaata cgatttttgg cgacagtgcc aaccttccca tgataagaat
     5041 tgtaccgtcg agattttcga gtgtaagact ttacttcgat acctagtttt tttatcagac
     5101 gttgaatctt ctttttattg acatgaatcc cttgattctc taattctttt tttagtcgca
     5161 gacagccata gtctttatgc tccttgcgaa tttcaagcat tttttcttca atttcttggt
     5221 ctgggtttgg tctgtcaaac cgtttctgcc aatacatata ggttgcttta ggaaatttca
     5281 atgtttcaag aagctcaact agtttgaatg atcctcggag gctggcgatg attcgtgcga
     5341 ttgattcttg cgtctttgct gggcttcctg ttttcgcagc ttcctcaact cttttaaaaa
     5401 ggcattctca atttgaaggg atcggacttg cttttctaat gccttgatac gctcgcgttc
     5461 ttcagttgtt gtattttctt ttttgttttc tttttttcta gtcaaagtaa gtggtcgccc
     5521 tttctctttt gagagcccct caatacctgc ttctctgaaa ttacgcatcc aattggcaat
     5581 aagcgcaggg ttgttcattt ctaaagtgct ggcaacttct cgataggaca tctcacttgt
     5641 ttgatataac tctagcgcat ttaacttaaa ttgaacagaa tatttctgat tttgatgctt
     5701 tttcaataga ccttcctctc cgtattcacg ataggcattc acccaatcac ttacttgaga
     5761 cttgcttgaa ataccgtatt tgttggcaag atgccgatat tcgcccacgc cactaagata
     5821 ttctttaacg atttttagtt ttaattcaaa aggatatttt gccatacaaa taacgacccc
     5881 caaaagttag attttttggt ctaacttttg attgatccat ccgtgtacct ttttttgatc
     5941 tcactccttg tatttttgct aaatatccta atccaccttc tccttcaaga tactcttgaa
     6001 cgattgttga cttgaattca aagctatatt ttcccataaa aataccatcc cccctgaagt
     6061 tagattttgg tctaactttt tagggtttgg acatcaccag tcccattttc attcacgtaa
     6121 tgcaagaaac tgactgaagt cattaaacaa aaatctgagc tagaatgaag ttcattctga
     6181 ctcagatttg attttgcaca actcatcagt cttcgtaaaa tatattttgc ctaataagtt
     6241 tcttttaaag tatctataaa acacaaattt ttttgaataa catattcctt ccggaattta
     6301 tttcgttatt gtgtgatttc tcagagtaca atggatgtat ggaaaggatt caacgagaat
     6361 ttgctaatca gtcctgtagc tttgtctacc ttcataagtc tgttatccaa agcgctgtgt
     6421 ttactatcaa ctcattagct cttttattac cgtattctat taggcgaggt cgtgaccaca
     6481 cagtgagttt ctgtggaatc ccacagtatc gaagcatttt ctagaattta tatcgaaaat
     6541 aggtttttat tccatgaaat tatttgttgg taatgacgtt agttctgaaa aattagacgt
     6601 ttgcttccta acagacgacg atcagctatc tatattgact gaaaattctg ttgctaatga
     6661 cattgaaagg gctccattga cacgagaact gattcttgtg ttcaatgaaa acaatcactt
     6721 cggtcaaatc gttattgaga tggaattaaa cgtccatgta cagctttcat ccttcgatgt
     6781 ttttgattac gtccatataa ttgtgtaaaa gtgaagcatc aaaaaagcca ttgatctcag
     6841 ttaggagtac aatgtttttt gcagaaaaca tactcgaata ggactgatat caatgactca
     6901 agtacatttt acttttgaaa gcgaagaaat tcaagcaatt ataaacgaaa gcggtgcgaa
     6961 tgataccgca aaaacactta tgactatcat gtttaatcag ctgatggaag aacaacgaaa
     7021 tcaatatatt caggcaaatg cctatgaacg ttcagaagaa cggcaatcac aaagaaatgg
     7081 ttactacgct cgttcgttta caactcgaat tggtacgtta gaacttcatg ttccacgaac
     7141 cagagacggt aagtttagtc ctactatctt tgaaagatat cagcgaagcg aaaaa
//
LOCUS       DAPBCF010000095         6802 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.098, whole genome shotgun sequence.
ACCESSION   DAPBCF010000095 DAPBCF010000000
VERSION     DAPBCF010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.098"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..543
                     /locus_tag="RD508_002710"
     CDS             <1..543
                     /locus_tag="RD508_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7737226.1"
                     /translation="GKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDP
                     IEARLTYKEVSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQ
                     LIFTAKTPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTIS
                     AVSLLLLVLATFSYAVLRYI"
     gene            570..1034
                     /locus_tag="RD508_002711"
     CDS             570..1034
                     /locus_tag="RD508_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737227.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLEIYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRMKEKLIHDGSQSNKYKLQKTSE"
     gene            1031..1273
                     /locus_tag="RD508_002712"
     CDS             1031..1273
                     /locus_tag="RD508_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HDT7737228.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            1291..1593
                     /locus_tag="RD508_002713"
     CDS             1291..1593
                     /locus_tag="RD508_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737229.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            1664..3718
                     /locus_tag="RD508_002714"
     CDS             1664..3718
                     /locus_tag="RD508_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737230.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGSLDYQISEGFYPTLIDLIR
                     LDIFKDTDETMSVEESYRNEKILQVLEEELESDQRKVNQVSEVEANEEVPWERPIFPK
                     DESKEKEKGIIDEQADILTHKSIFEEENEVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEDPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVE
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLRISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQAQIPKWKKEYEIHQQELKEQEEKQRKKEKEREQLELKKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLTHPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            3718..6330
                     /locus_tag="RD508_002715"
     CDS             3718..6330
                     /locus_tag="RD508_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDT7737231.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFSEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNEEISEMI
                     GKRLLLESEKVVKE"
     gene            6327..>6802
                     /locus_tag="RD508_002716"
     CDS             6327..>6802
                     /locus_tag="RD508_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737232.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKIKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTA"
BASE COUNT         2548 a         1030 c         1356 g         1868 t
ORIGIN      
        1 ggtaagaagg gtacgccgac agctccttta aacgcaggat ctgaagtaca atatctagtc
       61 acacaaaaat ggcacacaaa aggcgtagac gctgcgtcag atcactacaa acaatttagt
      121 attcaagatc caattgaagc tcgtttgaca tataaagaag tttctgcgca agtaatagat
      181 aagagtaaag gaaaagatat tacttctgaa ggcacactaa cctatgatag caattcaaga
      241 acgctgaagt gggaagcttc cgctgacttc ttaagtaaca atcttttaga tggacgagaa
      301 attcagctga tatttacagc taaaactcca ttacaatcag aaaaaaatat tgataaccaa
      361 gccgtagtag cagtagataa tgtttctaat aaaacaaatg ttgtgacaat tggggttgat
      421 cctaacttgc cacaggtcat tgttcctaaa acaggttcta cacatttagt aacgatttca
      481 gcggtcagct tactattact tgtgttagca acttttagtt atgcggttct gagatacatt
      541 taaaataaaa aaacgaaaga atgaataaaa tgaaaaagtt aataatagta gttacttcct
      601 tgattgccat gattgttatt ttagtcggat gtagtaatga aaaaaataaa caaactaatc
      661 aagataatgg cgtattgaaa tcaggaacta tgtggaaaga agaagtaggt ggtcttgttt
      721 ataatttgaa aattatagac gagactacct gggaatactc tgagagtgta tggcatccag
      781 atcctgtaca aataacagtc aagaggcaaa aagactataa aggtttagaa atatacaaaa
      841 tagtagattc agctggtgtt agggaattta taaacaaatc tgattcttta tttattgttg
      901 ttccctatga gaagaatggc gtaaaaaaaa taatttttct tggatctagc aaggatgaaa
      961 agcgaatgaa agagaaattg attcacgatg gatcacaatc caataaatat aagttacaaa
     1021 agactagcga gtgattgcta gtctttttat ttgtcctgaa ggaggaatca cagtggcaaa
     1081 agctaaaacg ccatttgaaa aagccgcgtc taaaatctta gaacgccgcg gtgtatctga
     1141 aacacagtgg aaacaagaag tccttgaaaa agcacaattt gacctattac ggggaaaaga
     1201 caaggactta gaaggatata tctatcaacg tgaacgtgaa aagcttgttt tcgatgaaat
     1261 tattaaacac taaaaggagc gaacaatttt atgtttgaat caattacaat gaatttttta
     1321 acacaaccga aagtagtagc tgcggttgat atttttagag cattacaaac tgccgcaact
     1381 agtttgaaaa ataatctgat gatttttgct gctgttgcgg cagtggcttc cattgctctt
     1441 ggaggtattt tcttcttctt tgggcgaaga ggagctgaaa acgggaagac acacgtaggt
     1501 tatgtattgt tgggggtagg agttatttta gctgccgctt ctattgtagt ttcaatgttc
     1561 tcaatgtttg gacaaacccc acaaggacta taaaaaaaca agtagaagga gtaaaaagta
     1621 cgtggctact ttttactcct ttttttatgg aaggagaata ttcatgtttt ttacgatttc
     1681 aggcaatgca aaattggata aagagttaat aagaaaagca acgaagaaag tgggaaagcg
     1741 tacttccttt ttaccgaaaa caattaaata ttctgtcatt gaaacggaag aacagctaca
     1801 tgtgttagga caagtgttag aacaagagaa tcaatcttct gttaaattga ctctcacgtt
     1861 acatgataaa gaaggaaaaa tagaaaaggc tggcacagaa tacgtttttg gctcactgga
     1921 ttatcaaatt tcagaaggtt tttatcctac attgattgat ttaatccgcc tagatatatt
     1981 taaagatacg gatgaaacca tgagtgtgga agagtcttat cgaaacgaaa aaattttaca
     2041 agttttagaa gaagagttag aaagcgacca aagaaaagtg aatcaagtga gtgaagtcga
     2101 agcaaacgaa gaagtaccat gggaacgccc aatctttcca aaggatgaat caaaagaaaa
     2161 agagaaagga attattgacg aacaagctga cattttgact cataaatcaa tatttgagga
     2221 agagaacgag gtaatgggtc aattggaggt agatcccttt gaagaaacaa tggaggatga
     2281 agagacggcc gaagtagaag ttgatccagt tgaagctaat gaagacccaa catggactga
     2341 aggggattct caggaatata ttgaaccact tatcagtgaa gaagtagaga aaaatgaaac
     2401 agagatacaa aaggcaacgg tatttgatta tattttggat caatatccgc cagagcatga
     2461 atggatgaaa gaaaaaaata aattattttt aaatgaactt tattcgaaat atcaattacc
     2521 tcaaacctat caagcatttt tagagagtaa agaagaatta atctcacagg gtaaaggcac
     2581 acttttagaa cagttagagt ctgtccaatc aacaaattgg catgagcttg cacaagaaga
     2641 tttattagct acttttgaag aacgtcaaca agaaacagat caagaaatta atgagtatgc
     2701 gacggaacag tcgtcgaatt gggagaaagc aaaagaggaa ctaaataaag aagaacagcg
     2761 agtgattgaa gaagaagtac aaaaaattaa agagcggtac gaaaagaaac gtgacaatgc
     2821 gtattccttg tgtgtagaaa agatcaacaa ttttactcag acgaatcaag aagcattatc
     2881 gaaagaaaaa gaaaacttat taaaagaacg tataaaagaa cgaaaagaag aattttaccg
     2941 agggttgcgt actgataagc taaggattag caaagaatta aatgaacaac tgaataaact
     3001 ctatcaaact acgactgaag ttctgatgga aaaacacgag cagatccaac aagaattaca
     3061 agcacaaatt ccaaaatgga aaaaagagta tgaaattcac caacaagaat tgaaagaaca
     3121 agaagaaaaa caacggaaaa aagaaaaaga gcgcgaacaa ttagaactaa aaaaacgtga
     3181 acaggatctt gcggaacaaa aaatggcgat agaaaaacaa cggctagaac aagaaaagga
     3241 aaaagaagca gctgctcgta aggaacgtca agaacaaatg gatacattgc gacaagcaca
     3301 gttaaattat ctgacacatc ctcaaccagt agctgctgtt caaacgccag tgaacaacca
     3361 agcaaattta actccttcac cccagcgttc ctttaacgga tggatggtgg gatgtattgc
     3421 aagtttaagc ttgcttctag gtggaggaac agtatttgct tttaatcata tcaatcaatc
     3481 ttcacaggct gattctgtag ccacaacggc gtcaatcaag gaagaagccc aggaacaagc
     3541 aagaaaagag tatgaacaac aattagaaga attattgaat cgtaccaatc agtcaacaac
     3601 agagtcaagc atggaaaata gcaaagagag tgattctagt aaggctaaag aaggatcaag
     3661 cgattcaact gtacaatcaa acacttccga aagttcagaa tcaaatgagg tgaaataatg
     3721 cgtgttagag aaacaacgaa gcgaaaagac aaacgattca atttagaaaa gaataggtat
     3781 ctttctcatt tctatcgcta tactccctca ggagaagagc taccagaaaa acatgacaaa
     3841 cgcatttcga aaaagatttt ttatagtgga cttgtatacc tccctttaga gtatttagta
     3901 acaagagtac cagaagtttt caaccgattg gaaattgtta agggaagctt acaaggaata
     3961 aatctgtttc aattacagga aatgccacag gtctttcatt ttgattcagc tggtttttgg
     4021 aatccattta ctcctacaac tagtttgggt acacgtttag caatttcgac agtttgtgtg
     4081 gttccagctg tacttatggg attgaaaatg gacatgtggt ttcgtcctct agcagatgga
     4141 caaaaagggg ataatcgatt aatgacctta aaagaaatcc aacagattta tccgcaaata
     4201 cctgaaacaa aaactacttt tccaggttat ggaggtattc caatcacaca ttacaaaaaa
     4261 tattggtaca ttcaaacaga tactgttaat acgtgtattg ttggtacctc tcgatcaggg
     4321 aaaggtcaga ttgaagtgtt agccaccatt gacaatttat ctcgtgcaga aaaacaaagt
     4381 tcaatggtcg ttaatgatcc aaaaacagaa ttatatgttg gtagtaaaga tgaactagaa
     4441 gctagagggt atgatgtata tgcctttaat atcaccgatc cactgcaatc aatgagtgat
     4501 aatccattgg cactcatcgt gaaatactgg aaacgaggag acatagatac tgcaacacag
     4561 ttaaccaata ctttcacaaa tacgatttat tatgatgcca acgcttcaga taacaaatac
     4621 tttaacgaaa acgcgcagaa agctgtcaat gcgcttattt ttgcgttgtt agaacaagct
     4681 gatcaaacag gagattactc caaattgaca ccgaataatc tcgttgagct tctttctgag
     4741 attggcggtt ttaattatta tccagatcca gacaatgaat tcaaacagtt gaatgcctta
     4801 gatgaattta tgaatcagtt gccacctgga aacattgcaa aaaaacaata tggggcaacg
     4861 aaaattggat ctgataaagc gaagggaaat attttatcaa cggcaatcac gggattgaat
     4921 ccatttactc taacgaaaat tgcaaagatg acttctcaat caacgattga ttataaatcg
     4981 gttgggtttc caaaatactt agatttgaaa ttacatgaaa gtcttttaaa tcaacgagtc
     5041 gtagtagaat tttatcataa gggaaagaaa tttcatgaag aacgtgtcaa agtaggctat
     5101 aaaggattta gtgaaatcaa ttttgattgt catttagttg caggtgatca agtttgttta
     5161 aaatacgatc atcaaggaaa agaatatgtg gcttggtatg aattttctca aagagtattg
     5221 aaagacgaag agggtaatat cgtttatcgg aaaaaacgag gagaaaccca tttgccagaa
     5281 ttagaaaaag aagccgttct aacattagat gaggaaaaaa gtaacttatt agtagagtct
     5341 attcggatgc actataccga taaaccaatg gctattttta tgcttacacc tgattatgat
     5401 ccatctaacc atatcattgt tagtattttt cttagtcagt tatataaaga attatctacg
     5461 caatgtgtta agactaaagg agataaatgt caccgcagga ttcattttat tttagatgaa
     5521 tttgggaata tgccaccaat ggataatatg gaaggaatca tgacggtcac agctggccga
     5581 aacatgttgt gggatctgtt tattcaatct tatcagcaac tttatgcgaa gtatggagaa
     5641 caaaacgcag cgattatcaa agaaaattgt cagacacata tttatattat gtcgacagat
     5701 gataatacca tcgaagaatt ttctaaaaaa gtggggaata agacggttga acaagagaac
     5761 agtaccatca attcattagg tatgaatact catatcaatc gcaatgttga ttcagatcgt
     5821 atcttaactc ctgaaagaat ttctactttt ttagaaggtg aaacgattgt actcgctcct
     5881 ttaaaacgac aagatttgaa aggtcataaa atacggccgt atcctatttt taatcatggg
     5941 gaaacgaatc ttccttatgc ttatcaatat attgaagatt tcaatccatc gtgggatatc
     6001 aatgatatag acatacattg tacacatgcg gacttggatc ttaaggcttt acaaattgat
     6061 tatgattatt tcctaccaga tgaatatgct agaaatctct atcatggact gcatgatcaa
     6121 ttagaagaaa aaaacgaaga aaatatgttt tataaaatcg ttcaatctct tgagaatgag
     6181 acggctaaaa aattgttaat tcaattttac gaagaacaag cagcagatcg acttcaagaa
     6241 tatgttgaaa agttgatcaa aaatgaagaa atttctgaaa tgattgggaa acggttgtta
     6301 ttggaatctg aaaaggtggt gaaagaatga tcattggagg aattttttct ggcatagccg
     6361 actggtggtc aggcttattc ggagaagggg atgcaaaccc caaaaccgta acgaaagtct
     6421 tacaagatta tggtaattat ctgcagtatc aagatgtatt cagttggatt tgtaatactt
     6481 ttttatgggg tttgattaaa gggttatata atctcaatac tttactagaa aaaacaattt
     6541 atcaaagctt tgatttaaaa gacttattga acgccgctgg tgttaatgaa ctgtttcaaa
     6601 gtttgattag taaggtattg gctctttttt gtgtcgtcac attaatttat ttaggcttaa
     6661 aattttttat gagtaaacat ccaccaaaaa tcaaaaatat cttggttaat ctatttatgg
     6721 ccatgatttt gatttttggt ggtagttctt taatcgatga agggctaaat attagtaaaa
     6781 acttttacgg agacgtgact gc
//
LOCUS       DAPBCF010000096         6747 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.099, whole genome shotgun sequence.
ACCESSION   DAPBCF010000096 DAPBCF010000000
VERSION     DAPBCF010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6747
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.099"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            682..1650
                     /locus_tag="RD508_002717"
     CDS             682..1650
                     /locus_tag="RD508_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7737233.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1661..2476
                     /locus_tag="RD508_002718"
     CDS             1661..2476
                     /locus_tag="RD508_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HDT7737234.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2544..3254
                     /locus_tag="RD508_002719"
     CDS             2544..3254
                     /locus_tag="RD508_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7737235.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3290..4789
                     /locus_tag="RD508_002720"
     CDS             3290..4789
                     /locus_tag="RD508_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDT7737236.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKNVSTEDFFNYCRLEESG
                     VTVTSGTDLPLFITDIPESIIRAVFRRFPEGEEVWEKETSFTTTELLKSFTSNSFKVN
                     GLSEYGEIKVGKSASLAVFSEDLCTDDWQKVMAAEVIATYLDGDLVYKK"
     gene            4837..6237
                     /gene="yfcC"
                     /locus_tag="RD508_002721"
     CDS             4837..6237
                     /gene="yfcC"
                     /locus_tag="RD508_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDT7737237.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            6270..6437
                     /locus_tag="RD508_002722"
     CDS             6270..6437
                     /locus_tag="RD508_002722"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737238.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFTGSVAKF"
     gene            6491..6747
                     /locus_tag="RD508_002723"
                     /pseudo
     CDS             6491..6747
                     /locus_tag="RD508_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT         2159 a         1042 c         1420 g         2126 t
ORIGIN      
        1 aattcaccaa aaaggtgagt aatgccattt ttgaaaattg agcttgtttt atgtctacat
       61 ctgtatccgt atataatcca aaggattata aactcagaag agtctttatt ttttctgaat
      121 ataactactg tatcaaaaac aatcgattat gagacaaaac aaaatgacct cttttattta
      181 agaaaggagg tcattttttg tatcataaat tgtattaaaa tcaatgtatc actttttaat
      241 cagttttaag accataaatt gcgtactaaa agaaattctg caattcaaaa taaagcattt
      301 taagccattt tcaaatttaa gtgcacccat ctacccgtca aatcacttta ttttccactc
      361 cagtagtttc ctaattcaac tgtgtgcaaa aacgatttct tctaaacaaa tcaagacaaa
      421 cttataaacc ttcatcccag caccataatt atttaaatca taggcatttt tcgaaattag
      481 tatatgtact caagtttcac tgcagattat ttatattttt tagagaaata aatttttcct
      541 attgacaaac acaaagaaag cggatacaat gcaattatgt cacatgacgt tatatgacgt
      601 tatgtgatat ctttacattt aatcagttac ttttattttg gataaaatta acatttttaa
      661 aattttaagg aggaaatgtt gatggatgta gcaaaaacgg ttaacgcaat tgtagaaaaa
      721 aatgatggag agatttctgg aatttatttg gtggcttgtg gcggttcgct ggtagatatg
      781 tatgtctcag attattttct taaagccgaa gcatcgaagt gtattacagg cttatataca
      841 gcgaacgaat ttaaccatgt aaccccaaag caattagatg ataaatctgt tgtcattcta
      901 tgttctcatg gaggaaatac agcagaaacg gtaaaagcag gagaagtcgc tcaagctaga
      961 ggagctgtga ctgttggtct gactcataat aaaactgcgg atttattaaa ggtttctgat
     1021 catagtttcc tttacgaatg gggagatgat gcaaaaatag tcaataatcc tatggccatc
     1081 attcttgatt taactgtatc tttggtcaat gttaccgaaa catttgaaca ttacggtaaa
     1141 ttcagagaag gcatgaaggt tatcgatacc gtaattgaaa atggcattaa gcaggtgcag
     1201 gatcgtatta aagtgtttgc tgataagtac aaagatgaaa caatgtttta tatcttaggt
     1261 agtggaccat catatggaca tgcttatggt ttttcaattt gctctttgat ggaaatgcaa
     1321 tggcttgatt caacttctgt tcattctgga gaattcttcc atggaccttt tgaagtaaca
     1381 gacaaagata cgaattttat tctcttgatg agcattggac gcactcgtgc tttagatgaa
     1441 cgggcaaaac gattccttga taaatatgca gaaagagtag aaatcgttga tgcaaaggaa
     1501 ctaggattgg atatgatatc agatgaagtt tctgaattct tcaatcccat tttattctac
     1561 agtattcttt cagaatatcg ttcagcttta gcagatgtac gcaatcatga tttagatgtt
     1621 cgtcgctata tggggaaagt ggagtactag gaggattaaa atgaaggtat taggcttagg
     1681 tgataacgtc gtcgataaat atgaaaatct gggaattatg tatcctggag gaaattcatt
     1741 gaattttgca gtttttgcaa aaaaactggg acatgaaagt agctttatgg gagtttttgg
     1801 ctcagatgag gaggcagctc atgttttatc agcaataaaa gaaataggac tggacaacag
     1861 tcactctcgc tttgaaaaag gcgagaatgg ctgtgccaga gtgaagattg atgagggcga
     1921 ccggattttc cttggcagca attcgggagg tgttactcgt gaatacccga ttcagcttac
     1981 tgaagaagac agagaatatt taaaccagtt tgaattgatt catatgggat tatatagcca
     2041 tgtcaatcat ctattagaag agttacaaaa tgtttctgga aagatttctt atgatttttc
     2101 tgacgacttt acggaagaag aggttcagcg ggcaattgat aaagttgatt ttggcttctt
     2161 ttctatagaa gacttttccg atgaagaagt aaagcagttt ttgatgaagc atttttgtga
     2221 gcgaaatgat gtattgattg caacccgagg agaaaaaacg gctattggtt atgatggagc
     2281 aaagttttat gaagtgaacc ccgtgctaga agaaccagtt gatacaatgg cagcgggaga
     2341 ttctttctta acagctttcc tactttattt tctcgaaggg gacgatatag tcaccgcgat
     2401 gaaaaagggg aatgaatttg ctgggaagtc ttgtctggtt gacggttcgt tcggctttgg
     2461 tattcattac gattgagctt gttttaaatt cctgcatttg ataacctaaa gaaagaaatc
     2521 ccggtaaagt ggaggttaaa aaaatgctgg atacaaatgc acaattacca ttgtacttac
     2581 aattaaaaga aatattaaaa aataaaatca atacagggga gtatcccgag aatacgaaaa
     2641 ttcccgctga atcagagctg atagaaagtt atgaggtcag ccgaatcaca gtgagaaaag
     2701 cagtagaaga actggtagaa gaagggtacc tacttaaaaa acaagggaaa ggaacttttg
     2761 tcaaccggca taaagttttt cgtaaaattg aatatattat gggtttcagt gagagttgta
     2821 aatctaatgg ttttacaccg actagcattg ttttggaacg caagatcatt ccagcaactg
     2881 aagggatggc aaaaaaactc gatatcgctc aaggtgatga tgttttatat atccagagaa
     2941 agcgaatggc ggataacatc cccattatgt tagaaaacaa ttatttttct tatgaaagat
     3001 atagtttctt aatggaggaa gagctgactg attctttgta tgaagtactt aaagtccaag
     3061 gtaccttagc catcaatcct ggggaaactg cacttgaaat tgtcacagct gatgaccaaa
     3121 ttgccaaaat aatggaagta gctgttggga cgcccttttt ctttatggat actttaatca
     3181 acgatcaaaa caacatacca attcatgtag gtaatcaata ttacctggga gaagtatatc
     3241 gtttttactt atgatttcct gtttggattt caaggagtag attttattta tgaagcaaat
     3301 attgcggtca aaaatgattt ttgatggaga gcagccacct ttcaaaggtt atattgtaat
     3361 caatgaaggg atcattgaaa aggtggaaaa caactggaat tacagtgatc tattaaatga
     3421 aaacacggaa ttaattgctt atgatgatca attcgttatg ccagcaattc atgataatca
     3481 tgtatttttc agtggttatt tggctatgaa tgctggcata gatttaagcg atacatcttc
     3541 agctaacgag gctgtagagc gtattaaagc tgtaatgaac cataaaaaag cagatgaacc
     3601 aatttatgct catggctggg atgctgccct gtggaaaact gacccatcag aagagctatt
     3661 gaatgaaata aaccactttg gtccaatcac agcgatcgac aaaaatcgca gccattgttg
     3721 gatgaatgct attgctaagc agacttatgg ttttacagaa aaagaaacca gtgctgaaag
     3781 tcgagtatta ttaattaagg aaatgctagc aaacaaaaag cttttagcag aggtttacgc
     3841 tgaatttgaa gcattactgc tttcaaaagg tgttatatca atgaaagaaa tcgtttttga
     3901 tgacgcagaa tttctttcta atatacctca gaggaaaata cttagtaacc tatatgtgca
     3961 ggcagtccaa gaacctctac agcatgaact tctatatgag tataaggaaa aagttttccc
     4021 tgaaaaggtc cgctttggtg gagtgaagat catggtagat ggtgttgttg cggatagaag
     4081 tggagatatt tacggtgttt atcagtcagg agtagcttca cccgagattg actatgaggc
     4141 aattaaagca gaagttgctg cattcaatga agtagagatt ccttgctgtt tgacaacgga
     4201 aggagataaa gcgggttata aagctgcgtc aattcttgtc gaatttggaa agcggttacc
     4261 tgaaggcgtt tttaattcga ttagtgattt ggaaatggtt actcaaaaga cagcagaaaa
     4321 aatgaacgaa ggacaagtag tagcagaggt atatccacaa attctcggct tgaatcaaac
     4381 gttagaagag gcttacatgt caactgttat aaaaaatgtt tccacagagg acttctttaa
     4441 ttattgtcga ttagaggaaa gtggtgtaac agtcactagc ggtacagatt taccgctgtt
     4501 tattactgat attcctgaat cgattataag agcagtattc cgtcgttttc ctgaaggaga
     4561 agaagtctgg gagaaagaaa caagcttcac gacaaccgag ctgctgaaaa gttttacaag
     4621 caacagcttc aaagtaaatg gtttatcgga gtacggagaa ataaaagtag ggaaaagcgc
     4681 cagcttagct gttttcagcg aggacctctg tactgatgac tggcaaaaag tgatggctgc
     4741 ggaagttatc gctacctatc ttgatggtga cttagtttac aagaaataat gcttttcgat
     4801 ataacgttat aaaacgaatt gaagagaggt taaaaaatgg aaacaatgaa aagaaaattc
     4861 accttcccac atagttatac attgattttt atcttaatta ttttggctgc aattttaact
     4921 tggataattc ctagtggtca gtttgagaca gttgttgaaa acgtcgcagg tatggaaaaa
     4981 acaacggttg ttccgggaac ctatcaccaa atcgataagg cagattatgg acaaggtttt
     5041 tcctctatac taatggcacc agctgaaggg attatttcag ctgttgaggt tgttgctttt
     5101 gttctcatcg ttggtggtgc cttcgggatt atcctaaaaa cgggagccat cgatcgaggg
     5161 ctgtttacct tagcaaaagt tctgggagac aaggggatct tagttattcc gatgtcgatg
     5221 attctattca gcttaggagg atcaaccttt ggcatgagcg aggaagtcat tcccttattt
     5281 gcggtgttta tttctctgat gttttctctt ggctatgatt ccatgactgc gatcttgatt
     5341 ctatttttaa gtacacaagc gggatatgtt gggtcgacga ttaatccctt caacgtttta
     5401 atcgcacagg gagtagctgg cgtttacgga aatcccctgc tttggtttcg gatgctatcc
     5461 tggattgtca ttactgggat ttcaattgtt ttcaccatgc tttatgctag cagagtcaaa
     5521 aagaatccac tgtcctctat tgtttatgag agtgatttaa aggttaagca taagtttcaa
     5581 aattttgaca ctgaaaaaga gttttcaaca caagataaac taattatcgc cggttttatc
     5641 gtaggtttag gaatcatgat ttggggtatc atttccaagg gatggtatat ggttgaaatt
     5701 tctgcactat tcttaggatt aggtcttttt gctgggggca tcgctagatt ttctcaaaag
     5761 gaaattgctg aagcttttgt cgaaggctgt tcagatttcg cctatgctgc tgtaatcatt
     5821 gggctagcta gaggagtctt ggtaatcttg gaaggtggaa tgattattga cactattcta
     5881 aacagcttgg ctaacctttt aggtggtctt ccaaaattcc tgttcactac gattctactc
     5941 atttctcaag taattgtttc cttttttgtt ccatcctcct caggagctgc ggcattaacg
     6001 atgccggtta tggcaccatt gggtgatcta atgaatgtaa gtcgtgatgt tgttgttcta
     6061 agtaaccagt ttggaaatgg tttaatgaat attatctccc caactagtgg tgtattactg
     6121 gcaggattag ccatcgcaga gattaatttc tctaaatggt ttaaggttgg cttcaaaata
     6181 tttgccatct taacccttgt ttctgctgtt ttgttataca ttgctacact cttttagtct
     6241 taatcatcca ttaataggag gcaatagtta tgattaaaat aaatcaatta gcaggaatga
     6301 atatccacta tttattttat tctctcaaag aatttttcgc ttatcaacag aaaattggta
     6361 tttcttctgt tgaactttgg ggaggtgctc cgcatttttt catagatgct tttactggtt
     6421 ctgttgcaaa gttttaaatc tactatcaaa taaggtagaa taatagaaaa agatagcagg
     6481 aggaatgacg atgaatcatt ttaaaggaaa gcaatttcag caggatgtga ttattgtagc
     6541 cgtgggctac tatcttcgtt ataaccttag ctatcgtgaa gttcgagaaa tcttatatga
     6601 tcgtggcatt aacgtttctc atacgacgat ttatcgttgg gtgtaagaat atggcaaact
     6661 actctatcaa atttggaaaa agaaaaataa aaaatccttt tattcatgga aaatggatga
     6721 aacgtacatc aaaattaaag gaaaatg
//
LOCUS       DAPBCF010000097         6370 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.100, whole genome shotgun sequence.
ACCESSION   DAPBCF010000097 DAPBCF010000000
VERSION     DAPBCF010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6370
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.100"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            206..1480
                     /locus_tag="RD508_002724"
     CDS             206..1480
                     /locus_tag="RD508_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7737239.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQQMFPGFYTGLFSTSANGEKIYGTLNAI
                     QVFCEALMMGIVPIIMRKLGVRNTLLLGVTIMCVRIGLCGFASTPLSVSCIKMLHALE
                     VPLFTLPMFRYFTLHFDTKLSATLYMIGFQIAAQIGQVILSTPLGILRDNVGYQPTFK
                     IISLIVLLAGIYAFFILKQDDRDVQGDPFIRG"
     gene            1534..2961
                     /locus_tag="RD508_002725"
     CDS             1534..2961
                     /locus_tag="RD508_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HDT7737240.1"
                     /translation="MTKKAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPGDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDRLYMKPVRELEQLRVG
                     SGVETTVNLAGEIIIAQDASFKEALIDVLLTKSKNQEIKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            2974..3846
                     /locus_tag="RD508_002726"
     CDS             2974..3846
                     /locus_tag="RD508_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7737241.1"
                     /translation="MLIGSIEAGGTKFVCAVGDEDYRVQDQIICPTTTPRETLKKTVD
                     YFKQFDINALGIASFGPIEIRKNSPKSGYITSTPKVGWRNVNVLGYLQDELNVPMSWT
                     TDVNGSAYGEYIMSTLSNEKINSLVYYTVGTGVGGGAVVDGKLLGSFGHSEMGHTFVK
                     RHPDDIDFKGICPYHGDCLEGLVAGPTFEARFGKKGEDVSLTDPIWDVMAYYLAQAVI
                     QTTLIIRPDKIVFGGSVVNEKLLEKIRVNVNKLLDDYVEIPPLSKYITRPLIKNNGSA
                     TLGNFALGLNQLQE"
     gene            3941..4936
                     /locus_tag="RD508_002727"
     CDS             3941..4936
                     /locus_tag="RD508_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7737242.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKNN"
     gene            5619..6236
                     /locus_tag="RD508_002728"
     CDS             5619..6236
                     /locus_tag="RD508_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7737243.1"
                     /translation="MAKIGYARVSSLDQNLDRQLELLSECDKIFSDKASGKDTNREGF
                     QEMMKFIREGDIVVVTELKRLGRNNKELTETMNLIQLKKATLEVLNLPALTGITDDNL
                     RRLLNNLIIELYKYQAEEERRYIRETQQQGIALAKAKGKYKGGTPKYRENDPRLQLAF
                     NLFLTGSTDKEVEELTGINRRTFRRYRMKHGITNEVREQKNKSFS"
BASE COUNT         2241 a          869 c         1234 g         2026 t
ORIGIN      
        1 tataaaaaat agtgccatta aaaaagaaaa gcgacacacc aataaaagtc atatcctgtg
       61 acattatatg gcattatcca aatagaataa ccggttgaca tgtaagcgga tttcttttat
      121 aattttagga gtacaagtcc ttttctaaaa atgttaaccg gttatcatga aaggggatac
      181 aaatatatcg ttggaggata aaaatatgtc aaaagttaac gtatttaaaa atcaatctta
      241 tttacaaagt tcagctacat tattactatt ttttgcttct tggggtgttt ggtggtcatt
      301 ttttcaactt tggctaacat ctgaatcaaa tggtttaggg ttatctggca gtgctgtagg
      361 aacagtattc tcggcaaatt cgttagttac cttaattttg atgtttattt atggaacatt
      421 acaagataaa ttgtatatta aacgaaattt attaattttt gcttctgtat tagcgacact
      481 tgttggacca ttttttatat ggatatatgg gccattgcta gataacaatt ttaatttagg
      541 cattattatg ggagcgctat ttttgtcagc tggatattta gcttctgtag gagtttttga
      601 agctgtgtca gaaaggttta gtcgtttatt tggctttgaa tatggacaag caagggcgtg
      661 gggatcattt ggttatgcct tggtagcgct tttggcagga tttttatttg taaaaaatcc
      721 tcatttaaac ttttgggcgg gatctttctt tggttcttta ctattgttaa atttattatt
      781 ttggaaccct aaagttgaac gggaagcaaa tcaaaatttt aatcaagaac aagctgaatc
      841 aaatagtatt ccttctttaa aagaaatgtt tgatctaatg aaactgcctc aattatggac
      901 gataatcatc tttattgttt ttacatggac attttatacg gtattcgatc aacaaatgtt
      961 tccgggattt tatactggtt tgttttcaac atcagctaat ggtgaaaaaa tatatgggac
     1021 attgaatgct attcaagtat tttgtgaagc gttaatgatg ggaattgttc caatcattat
     1081 gagaaaatta ggggttcgaa atactttgtt attaggtgta accattatgt gtgtacgaat
     1141 tggattgtgc gggtttgcct cgacaccatt atctgtttca tgcataaaaa tgttgcatgc
     1201 tttagaagta ccattattta cattaccaat gtttcgctat tttacacttc attttgatac
     1261 aaagctatca gcaaccctct atatgatagg atttcagata gctgctcaaa ttgggcaagt
     1321 gattttatca acaccattgg gaatattaag agacaacgtt ggctatcaac caacatttaa
     1381 aattatttct cttattgtat tactagcagg catatatgca ttctttattc ttaaacaaga
     1441 tgatagagat gttcaagggg atccatttat tcgaggataa tggaaaccaa cagaataaaa
     1501 aacaatttta tctagaaagt gagcgaatat attatgacaa aaaaagctat agaattaaca
     1561 aatacacgtt atcgtttggg atatcatgtg tctgcaccat caggatggat taatgatcca
     1621 aatggatttt gctattttga tgggtattat catgtgtttt atcaacatca tccatatagt
     1681 gctgaatggg gaccaatgca ctgggcacat gctagaagta aggatttagt tcattgggaa
     1741 tctttaccac ttgctttgac tcctggagat caagaagatg aaggtggttg tttttcagga
     1801 agcgctattg aaaaaaatgg tgtgttgtat ctgttctata caggacatca ctattatgga
     1861 gacaatgatc cagatcattt ttggcaaaat caaaacatgg cgtatagtac ggatggcatt
     1921 cactttacta aatatgaaaa aaatcctgta atagcaaaag caccagaaga taacacacat
     1981 catttcagag atccaaaagt atggaaacac gatgaaaaat attacatggt tttgggtagt
     2041 caagaaaaag atggattagg tcgtgctatt gtttatcagt cgttagattt attaaattgg
     2101 gattacattg gaccaatttc taaagcgaag gaagtactta cagaaggatt tatgtgggaa
     2161 tgcccagact tttttgaatt aaatggaaaa tctattcttt tattatcccc tcagggaatt
     2221 gaagcaaatg gaaaagatta tttaaatcta tatgaaacag gctactttat cggtgattat
     2281 gattatgaga cagcaaaatt cattagagga aatttttatg aattagataa gggacacgat
     2341 ttctatgcaa cacaaacaac tttatctcca gatggtagac gtattgttat ggcctggatg
     2401 gatatgtggg aaagccctat gcctgaaaaa gtagacggat gggcaggagc attaacgctt
     2461 cctcgagaat tagagttaat tggagatcgt ttgtatatga aacctgtgag agaattagaa
     2521 caacttcgag ttggcagcgg cgttgaaacg acagttaatt tggcaggaga aataataatc
     2581 gctcaagatg cttcattcaa agaagctcta attgatgtac tattgactaa atcaaaaaat
     2641 caagaaatca aattttcatt aaaaacaaaa gatgaagagt taatcaatat tttttattct
     2701 aaggataaaa atgaatgtac cttaactcgt aacggcaaaa atgatccaag gtatggaacc
     2761 attcagatgt gtgatagatt atcacttcga gtgtttatcg ataaaagttc ggcagagatt
     2821 tttattaatg atggcgagct tgtttttaca gagcgttatt atacagaaaa tcaaccaagt
     2881 atgcatttga gtgttagtga agaagctttt gtctcgagta caatttatca tctaaaaaaa
     2941 gatgcaattt cttacgagta aggaggtttt atgatgttaa ttggtagcat agaagcaggt
     3001 gggactaaat ttgtatgtgc cgtgggagac gaggattacc gagtacaaga ccaaataatt
     3061 tgtccaacga ccacccccag ggaaacattg aaaaaaactg ttgactattt taaacagttt
     3121 gatataaatg cattaggtat tgcatcattt ggtccaatag aaattcgaaa aaattcacca
     3181 aaatcaggat atattacgtc tacaccaaag gtgggatggc gaaatgttaa tgtgttaggt
     3241 tatttacaag atgagctgaa tgttccaatg tcttggacaa cggatgtgaa cggatcagct
     3301 tatggagagt acatcatgtc cactttatcg aatgaaaaaa taaattcatt agtttattac
     3361 accgttggta ctggcgttgg tggtggagct gttgttgacg gaaaactatt aggatcgttt
     3421 ggtcattcag aaatgggcca tacgtttgta aaacgccatc ctgatgatat tgattttaaa
     3481 ggaatttgtc cttatcatgg tgattgttta gaaggcttag ttgcgggacc aacgtttgaa
     3541 gcacgttttg gaaaaaaggg tgaagacgtt tctttaacgg atcctatttg ggatgtaatg
     3601 gcctattatc tagcacaagc tgtgattcaa acaacattga ttatacgacc ggataaaata
     3661 gtatttggtg gaagcgtagt aaatgaaaaa ttgttagaaa aaattcgtgt taatgttaat
     3721 aaattattgg atgattacgt ggaaatacca ccgttaagta aatatattac gcgtccttta
     3781 attaaaaata atggatcggc aacactagga aactttgctt tgggcttgaa tcaattacaa
     3841 gaataaaaca tagaaaaaat atcgattatc aggtatagta gttctataga gttctttttt
     3901 tcgatagtta attattgcat tatttaggag agacaagaga atgcgcccaa aattagaaga
     3961 tgttgccaaa agagcaaatg tatcaaaaac aactgtttca cgtgtattaa acaatcgtgg
     4021 ctatttaagt caaaaaacga ttgataatgt ttataaggct atagaagaac tcaattatca
     4081 accgaacgtt gtagcgcgtc aattatttca aaagaaaact aacattgtcg ggttactatt
     4141 tcctacagta gccaatcctt tttttagtga actcgttgag gcattggaaa aaaagttata
     4201 tgaaattggt tataaggtat taataggcaa ttcgatgaat aataaagaaa aggaaacaaa
     4261 ttatttaaat cagttattgt ctgatcaagt agatggttta attgttggta cacataacca
     4321 aggaattcag gaatataaat atcagaattt accgattgtt gcaattgatc gagtgatgaa
     4381 tgaagatatt ccagttgttg aatccgataa ctacaatggt ggaaaacttg caaccaagtt
     4441 attaattgca caaggtgcaa aaaatattat tcatacaaac ggtccaattg acttacagac
     4501 tccggctaat cgtcggagac tagcctatga agatactatg aaagcatatc agttaattcc
     4561 acgaactgtg acattagatt tcaatatttc ttatgtaaag aaaaaacaga tttttttcca
     4621 aatgtttgag gattatccta aaatagatgg tatttttgct tcaaatgaca tcgatgcggc
     4681 cctaatatta caagtagcaa aagaaaaggg gttaaatgta ccagctgatt tattagtagt
     4741 cggatatgat ggtactttaa tgactcggag tatattacca gatctgacaa cagtaataca
     4801 accaattaat gatatagcag acacagctgt tgctattttg atgaaacgaa taaataaaga
     4861 agaaacaaaa aaggaatata ttttacctgt cacattatgg atggggaaga catcagtaaa
     4921 gaaaaagaac aattaaattt ataaagacta tcaatgataa tttcattatt aattcgtgat
     4981 ataaaaaatt gttaaatctc ttataataga ctatgataca aaatcatgct tttaatctgt
     5041 gtagatgttg ccaaatattt gaaagacata gaacttgtca gaaaaacctt aacaattcct
     5101 caatgggcgg ataagctagg caaaagggct ggcataaatt tttcagtcct tctaacagaa
     5161 tcaattgcag ataaagcaga taacattctt cgttctggaa gaaataatta gaactcaaaa
     5221 gggtcagaaa cttaaaagtt tttgatccct tttttattcc tcatttcata gcttttttag
     5281 tagctcaatt aattaggtca gaaagttact tttttaaaag gacaccagag tataccctgt
     5341 tgggctcttg gtgttctatt gaatgtaaat gagtgtcatt tttatattta attggcacag
     5401 ttttttctaa ttatttgtca tattcatagt caactatagc tacaaaagca actaattttg
     5461 gagatagatt gagatattta aaaatctatc atgaaaaatt agttgctttt gtcacttagc
     5521 gctgaaaatt tatgccattt atctagaaaa atgacaacag agttgggcaa cagaatttaa
     5581 aaatgatccg gatttcagaa ttttaaagga gttttattat ggcgaaaatt gggtatgctc
     5641 gagtaagcag cttagatcaa aatttagacc gacaattaga attattatca gagtgtgata
     5701 aaatttttag tgataaagca agtgggaaag ataccaatcg agaaggattt caagaaatga
     5761 tgaaattcat acgtgaaggt gatattgtcg ttgtgacaga attaaaacga cttggacgaa
     5821 ataataaaga gctaacagaa acgatgaatt taattcagct gaagaaagct acactggaag
     5881 ttttgaattt gccagcgtta acaggtatca ctgatgataa tttacgtcga ttacttaata
     5941 acttaattat cgaactatac aagtaccagg ccgaagaaga acgtcggtat attcgcgaaa
     6001 cgcaacaaca aggaattgca ctcgctaaag caaaagggaa atacaaggga ggtacgccaa
     6061 aatatcgtga gaatgatccg cgacttcaat tagcatttaa tttgtttttg actggatcta
     6121 cagataaaga agttgaagag ctaacaggga ttaatcgtag aacgtttaga agatatcgaa
     6181 tgaaacatgg tattactaat gaagttaggg agcaaaaaaa taaatctttc agttgaggct
     6241 aatataattt tgcaagaaag ggatttttat gaaagaaatt agattttcaa atcaaaatat
     6301 gcagaattac tataatgaaa ttatgaatat ggaaactagt gaattgaatt taattatagc
     6361 cgaaaaaaaa
//
LOCUS       DAPBCF010000098         6189 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.101, whole genome shotgun sequence.
ACCESSION   DAPBCF010000098 DAPBCF010000000
VERSION     DAPBCF010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6189
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.101"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            4..243
                     /locus_tag="RD508_002729"
     CDS             4..243
                     /locus_tag="RD508_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737244.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            310..519
                     /locus_tag="RD508_002730"
     CDS             310..519
                     /locus_tag="RD508_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737245.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            579..1250
                     /locus_tag="RD508_002731"
     CDS             579..1250
                     /locus_tag="RD508_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HDT7737246.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGKVFKQNIEKKMPVD
                     QINEHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQAFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1303..3279
                     /locus_tag="RD508_002732"
     CDS             1303..3279
                     /locus_tag="RD508_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7737247.1"
                     /translation="MAINRYVKKAGMLVGMLGIIASCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEIVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGIGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPTGYQKLTEDIAFKVNKNSFKEENRITVKNNQKAAI
                     PLTGSNGFQTYVLISCLLLGAGVLSAVVYFKKKA"
     gene            3294..4046
                     /locus_tag="RD508_002733"
     CDS             3294..4046
                     /locus_tag="RD508_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7737248.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            4062..4823
                     /locus_tag="RD508_002734"
     CDS             4062..4823
                     /locus_tag="RD508_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737249.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLISNGETKTIDQQT
                     GVFEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            4836..5096
                     /locus_tag="RD508_002735"
     CDS             4836..5096
                     /locus_tag="RD508_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737250.1"
                     /translation="MKLIKLLLFNLSCLTAVFLYCGLLFSQLSILPSYQLYLMRILNI
                     PAVSMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            5093..>6189
                     /locus_tag="RD508_002736"
     CDS             5093..>6189
                     /locus_tag="RD508_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7737251.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDFGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYTHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVND"
BASE COUNT         2261 a          972 c         1278 g         1678 t
ORIGIN      
        1 tagatggcgc gaccagtttt agaggcgatg gatatggata ctttgacaaa aggaaggtat
       61 gtacagctgt tagctcgtgg ttattcacct aaagaagtat tcaaagcctt atctaaagga
      121 acagatatgg aaaaagaaag attgcgaaaa gaattcgatt attggagaac ccataatgga
      181 atcaaggatt tgaaaccagc acggccagta attaaacgaa agaaaaagat aacccaagac
      241 tgaagtgtag agcgtatgtg atcataggct tttttatttt tgcaaaaaac aaggaaggta
      301 ggaaaactca tgaattatga agaaatcgaa aacagaaaaa aagtgtcgaa agaaatggaa
      361 gaaaagttac taaaaacgat gaagcaaaaa caccttaaaa gattatctgt cgcgcaatat
      421 atcaatgata tgcagttaac aggaaaagag aaagcttgtt tgttaggttc aatgaaaaac
      481 tttgaacagt tgagacgaac ttatagaatt catttttaaa actttttcta tggaaatgag
      541 aaaaagattt tttgttttgt ctgaaagggg gtagctggat gagaaaatgg ttatttggtt
      601 ttttaggagt cgctttaatc gtcttttgca gtgtgtttgg ctatgttagc taccaaaaac
      661 atgaaggaaa ggtgtttaag caaaatatag aaaaaaagat gcccgtagat caaatcaatg
      721 aacatgcaaa gagttataag gaggatgcaa cgaacgtcaa taatgatatg tctttggggc
      781 aaatgttgtc catacaaaaa gaagcaatcg aaatgggtgt caataaacaa gcctttgcac
      841 aaattcagat acctgcactt ggtttagcat tgccaatttt taaaggggca aatcaataca
      901 ctttgagtct tggagcggct acttattttt atgaagatgc cgaaatgggc aaaggaaact
      961 atgtcctagc aggtcataac atggaaatgc caggtgtttt attttctgat attcaaaagt
     1021 tgtcattagg ggaggtgatg gacttagtta gtaacgatgg cgtctatcgt tacaaggtaa
     1081 cgcgtaaatt tatcgtacct gagtacttta aattaatcga tggcgttcct gaagagaact
     1141 ctttcttgtc tttaccaaag aaaggagaga aacccttatt aacgttgttt acttgtgttt
     1201 atacgtcaca aggaaaagaa agatacgtgg tacagggaga gctacaataa caaggtttta
     1261 atcaacgcga gtcgttgaaa tatgaaatga ggagagtaaa aaatggcaat aaatcggtat
     1321 gtaaaaaaag ctggaatgct tgttggaatg ttaggaatca ttgcaagctg ctttcagggg
     1381 tatcaagtac acgcagaaga tgtcacgcaa aaaacgccac cagagaaggt caatatcacg
     1441 gttcataaat taatgtacga tcaaggaacg caattgaatg ttgatattga cgggatcaaa
     1501 aacgatggtt atacgcacga tcaatatcct acaggtgtaa cgaaatacaa caaggcagat
     1561 tatggtgatg ttgagtttac gttaggaaat attacggatc aagtattacc gagggaagat
     1621 tctgatctaa ctaacgcgaa agtggacgaa atcgtgaaag acgtagaaga caagggatct
     1681 aacagtgagt acgtcaagaa tgcaaccaac aaaattactt cagctgtaga tgaaaatggt
     1741 gagatcactt ttgctgatca accagcctat gtcaattcca aagggaatgt atatgtggtt
     1801 tatgaaagta aatccgctgc tggattagtc acacaaaaag caaaaccaat ggttgtgatt
     1861 gcgccaatga cagacaatac aggatcagga tttttaaaag atattcattt gtatccaaag
     1921 aacattgttt ctaagttgag ttttgaatta acgaaatttg gtgacgatgg cacagctcaa
     1981 agcaaacaaa cacctttaaa aggggcaaaa tttgagttat acaagggcga acctggaaaa
     2041 ggaacaaaat taggagatct tgtatcggat gatcaaggaa agctgactgc gactgatttg
     2101 acgttaggaa aatactattt tgtggaagtt ccttcagaaa ttgtagtggg atcagataaa
     2161 gaaccaacag ccgatcaata tttattaggc gcagacgctc gcaacgatgc gcacaataaa
     2221 ttaacctttg aaattacgaa tgacggtgtg acaagcgatt taaaagcttc atacgtaaac
     2281 tataaagcac cagtgatcga taaaacagta acaaatggaa caggacaaga acattctttc
     2341 caaattggtg acgcagtaaa ttatcaagga acgattcata tcccaacaga cattgcaggc
     2401 ggagcagacg gtatcacagt aaacggcgtg aaaagcgaaa cttctcctta cagtgtattt
     2461 aagtgggggg atacagcagg acaaggactt tcttatgtcg ctgctaaagc aaatatcaaa
     2521 gtaacaaata aagatggatc tgtggtatta aaagaaaata cagattataa aatccaaaat
     2581 tcagaaaatg gctttgtgat cgattttatc gtgaataatg gccaagtaag tgatactgta
     2641 gcaagtttac acggacaaga tcttcaaatg acttataaca tgtatgtaaa tgatagcgca
     2701 gctgttgcca atccattaac aaatagcgtg gatttcgttt ataacaacaa tccatttaat
     2761 caggaagaac accacgaaaa aacgaaagct gacgttgtga cttatggtgc aaaattctta
     2821 aaagtcgata gcggactatt tggaatagga atcaaagcaa caccgcttga aggcgcagaa
     2881 tttgctgcta aaaacgcaga aggaaaatat tatggtggat tagttgatac ggataaagac
     2941 ggtgtcaaag aagcagtatg ggtagacgat gtagcaaatg cagcgatcct aaaatcagat
     3001 aaagaaggtc actttgaaat cactggttta actgaaggtg aatattcact ggaagaaaca
     3061 aaagcaccaa ctggttacca aaaattaaca gaagatattg catttaaagt aaacaaaaac
     3121 tcatttaaag aggaaaatcg aatcactgtt aaaaataatc aaaaagcagc tattccatta
     3181 acaggtagta atggtttcca aacgtatgta ttaatctctt gcttgttgct aggagcaggg
     3241 gtactttctg cagttgttta ctttaagaag aaagcctaga aggatcaaaa ccaatgatta
     3301 tcaggaagcc taagaaaaag cgaatcatgg gtaaatggat cattgctttc tggttacttt
     3361 cagctgtagg tgtcttactt ttgatgcctg ctgaagcgag cgtggcgaaa taccaacaaa
     3421 atcagcagat tgccgcaatc gatcgaacag gaacggcagc agaaacggat tcttctttgg
     3481 atgttgctaa gattgagtta ggcgatcctg ttggtattct tacaattcca agtatttctt
     3541 taaaactacc aatttatgac ggaacgtccg acaaaatttt agaaaatggt gtaggtatta
     3601 cggaaggaac tggtgatatt acaggaggaa acggtaaaaa tcctttaatc gcaggtcata
     3661 gtggacttta taaagataat ctttttgatg atttaccttc agtaaaaaag ggagaaaagt
     3721 tttatatcaa agttgatggt gagcagcacg cttatcaaat cgatcggatt gaggaagtgc
     3781 aaaaagacga actacaaaga aactttgtca cttacttaga accaaatccc aatgaagatc
     3841 gagtaacgct aatgacatgt acgcctaagg ggatcaacac acaccgtttt ctagtgtatg
     3901 ggaagcgagt aacctttaca aaatcagaat taaaagatga agaaaataag aaacaaaaat
     3961 tatcttggaa atggctttta ggaagtactg tttttctttc agtcatgatc attggttcgc
     4021 tatttgttta taaaaagaaa aaataaagga gggtaaccaa catgagaaat agaaaatggc
     4081 tatttgtttg tgcagccgct cttttttctt tcactgccta cacacagttg acgtttgcag
     4141 acagacaaga aagcacggat agcacagaac aaacaatcca aacgtcagat agcagcacga
     4201 ttcaaagcag cgatgaaacc gtcgattcgt caacagttga ttcttcagaa gaacctaaaa
     4261 ttgctgaaga cgatcaaata gtcaaacaga ccattcacgt tcaaaaaatt atttcttccg
     4321 aacaattaga caaccagggg caaaagcttg aaaaacaaga aggagtaaat ggcgcgaagt
     4381 tttctgttta tgatgtatcg gacattttac aaaagatgga tgttaaggat ctcactactg
     4441 accaaattga atcccaatta aaagatcgag tgaaaaaact atccagtgat caactgaagc
     4501 taatttctaa tggagaaaca aagacaattg atcaacaaac aggtgtcttt gaattctcgg
     4561 tagaagtaca ggcaaatcag aaacaagctt attatattgt caatgaatca agtcctgaaa
     4621 acatttctaa tagcgaggat attttgctat taacacctgt ttctgataaa aatggtgaat
     4681 tcttaaagga tgtgtggatt tatcctaaat cagaagcttc gcaacctaaa gaagaagtaa
     4741 aaaaaatcgt atctactggc gtaaagaaaa acttctttga gaattgttgg gattttgtta
     4801 ctcacttgtt ttctagagat taaggaagaa ataagatgaa actgatcaaa ttattattat
     4861 tcaatctttc ttgtttaacc gcagtctttt tgtactgcgg tttattattt tctcaactat
     4921 ctattttgcc aagctaccaa ctatacctaa tgaggatttt aaacatacca gctgtttcca
     4981 tgccgctaga tattatggaa aagctcatta ggaatccatt atttactacg atcaatttga
     5041 tcgttattgt cggaatttca ctagtcattt ataaaaaaga ggggatgaag ggatgaattt
     5101 taaacactcg tggacaagac ggttaaaata tgtttttccc ataatgatga tgttaggtac
     5161 attgtttggg ttaaaaacag ccaatgtctt tgctgaaaaa gttattgtcg atccgtcaaa
     5221 tccaatacag aacgtaaaga ataattttat tattccaaaa gatgttccta atgcaaaaac
     5281 aaatattact gtaaacggag cgtcaaaagt ttacaaatat catgttgatg ccaacaaagg
     5341 tggttttaca gacgactacg taggattagt ggagggaaac aaaaatatac gctatccttc
     5401 tttccaaaag gaatacggtg aaacaaacct tgttttagaa ggcgtaacaa ccaacaccaa
     5461 agtcaatatt gactttggaa aaatcggtac gtataacggg aaaaaagtca atatcaagct
     5521 agttttatct aatattcact tatactcgga tacgttgccg tggaatctac tagataataa
     5581 ctatacaaaa actcattttc gagacgatgg ctataaaaat acgaatggtg caatgagtaa
     5641 atctaaaaaa agaacagtac tttggatctc agacaatctt ttctcaggaa ttgtttacca
     5701 ttcaacacaa atgaatgtgc agctagtagc cacatatgag gacggtagcc ccgttcaatt
     5761 ttcaggagat acatttatca gttttaactc tttgaaccct gcaggaggaa aaagcacgga
     5821 tcttaaagga gaatataccc actatgacaa aatgaataca acagattggt atgtcagaaa
     5881 agatacggtt ctttcagaat ttaaatcttt ctacaacaat ctgaacgtgg taggtggcca
     5941 cccaggagga agctctaagc tgacacaagc ggataatgat ttcaataatt tgcatgataa
     6001 attaggagat ccgaagtttg gtcaaggtac tgtgtccttt aaaatatctg aagcaaatcc
     6061 gacgtttgtg attggttctt ctaatgttca aacctggttt actttatctt ctgcgacaat
     6121 ctttagtgtt gtacctgatc aacctgaaaa aacaggggtt gataaaaatg gaaataacgt
     6181 gaacgataa
//
LOCUS       DAPBCF010000099         6138 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.103, whole genome shotgun sequence.
ACCESSION   DAPBCF010000099 DAPBCF010000000
VERSION     DAPBCF010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6138
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.103"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            725..811
                     /locus_tag="RD508_002737"
     CDS             725..811
                     /locus_tag="RD508_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDT7737252.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="RD508_002738"
     CDS             complement(932..1621)
                     /locus_tag="RD508_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737253.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1866..2726)
                     /locus_tag="RD508_002739"
                     /pseudo
     CDS             complement(1866..2726)
                     /locus_tag="RD508_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(2727..3107)
                     /locus_tag="RD508_002740"
     CDS             complement(2727..3107)
                     /locus_tag="RD508_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HDT7737254.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3557..3844)
                     /locus_tag="RD508_002741"
     CDS             complement(3557..3844)
                     /locus_tag="RD508_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDT7737255.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3864..4088)
                     /locus_tag="RD508_002742"
     CDS             complement(3864..4088)
                     /locus_tag="RD508_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HDT7737256.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4543..4713)
                     /locus_tag="RD508_002743"
     CDS             complement(4543..4713)
                     /locus_tag="RD508_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737257.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4728..5261)
                     /locus_tag="RD508_002744"
     CDS             complement(4728..5261)
                     /locus_tag="RD508_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HDT7737258.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5282..6124)
                     /locus_tag="RD508_002745"
     CDS             complement(5282..6124)
                     /locus_tag="RD508_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDT7737259.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1625 a         1145 c         1031 g         2337 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcttac tttaactgtt gccatatctt ttgtagctcc
     2761 ttttgcatga tttttaggtt ttcggataag cgttgggcgt cgccaggatc aacgtcgtgt
     2821 tggtgtgtgt tgcaccactt ggcaatttga ttgatattcc cgccagcttt ggctaaatcg
     2881 cgcgcgattg cctgagcaat gtctggcgcc actttcggtg tcaccagacg cgcgttttgt
     2941 gccttggctt tcacgaaagc cggcacactc atttgcaaag cttcagctga ctgcttcagc
     3001 tttgcaaatt cggattcgct cactcgaaaa ctgatttgtt ttggctcgga tcgataggta
     3061 tattttttag aatgattgct agccaaatat tgattttgtt cgctcataag tcccaccctt
     3121 tcagtacgtc ctacggacgt atcgttcgca ataccattgt acctaaaaag gtacaataag
     3181 taaagctcac taaagctcac taaagggctt ggcaagctct atatttgcta gccaaatacc
     3241 tacgtatttg gtgcaaataa ccgcttgtca aaggggcgca agctccccct tgaatccccc
     3301 tcccccccac tctccacaat acaaaaaaga ctagcaaatg ctagccactt tttgtaaagt
     3361 ttcgcttgtt tcaccttcgg tgaaattgtt gcaaatcaat aattaggtag agctacattt
     3421 ttttcgttgt tcaaagattc ttatgccatt tactattaat aaatctataa atatgataat
     3481 ttttcggctc tataatttat gggactgatg aatcagaatt gattcttcag tcccattttc
     3541 attttattcc aaagaattaa ctccaaatac caatagaagc ccatcctcta tatacttgag
     3601 attccttact aacaatttct tgtaattcta ttaaagattt aggtaatcca aatttatgtt
     3661 ttaaaatata tcttccaaga aaactactta atttcatact aacttcacca acactttttc
     3721 cctcactgat ttctttagaa taaagaaaga gcttttcttt taagtcagga tagtcatcta
     3781 tagttgcttc attgtatact ttactaattg catttaaaag tttttcttct ttagtaaaat
     3841 ccattataat aacctcccta ccactacctt ctaggtgccc atggaccatg attaacccaa
     3901 ccattaacaa taatttttcc aatttctcct ttagcttgat tccaatctac ccaacatttt
     3961 tctttgttac aataaagacc atttccatag taagtagctg catcaacttt tattcctgta
     4021 ccgatgccag ctagacaagt tcctaatatt cctagaataa cacaatgttt taatactttc
     4081 tttttcatga ttgtttttcc ttttcgtttt tttaaaattg cttgttatat taaataatct
     4141 tagtaatttt attatataac attttattat ataacaatga ttaacgtcat aaaaagtagt
     4201 tttgaattca taatcgttta aataaaatta taagatcagt tatttaaaca gctagtagac
     4261 ataatgtcga tactaccaag taacgcctgt accaagggat ccaggcgctg attttgtgaa
     4321 tttttattgg tctaggttaa aagctctttt taaggcttgg ttttctgcgg ttgtttcttt
     4381 ctaattcttt gtgaatattg atcggtcatt ttttaaatac ttgttatttt tgtttgtgtt
     4441 tgttatgctt tttacatatc tcatattcat ttattattct tttctaaggt taataatagg
     4501 ataatctctt tcagaaagac tgctcgtacg agcagtcttt tcttatttat caagtttttc
     4561 tacaaatact tcctcatttt gactgttgta gtaattagga ttgagtttta gttccccttt
     4621 tttatttcct ttgttggcca ctgataataa cattgggcta aagcttaata ttcctagtag
     4681 gatagaaccg aatagcaagt gtttttttgt cataagtatt tccttcttca tttccatagc
     4741 tgccaccatt ttttccaatt ctttgtttgt tcgtccattg tttctgttgc ttcagaaaga
     4801 gtcgttgaac tattctctga agactcttcc gtataagtca actgcagttg ctcctgaagt
     4861 ttttcgattt gttggttggc ttgcagggtg agttgttgtt gctggtcgag tagtttttgt
     4921 atatgagaat tattttgctc tttgagggca agttgttctc gtaaaaattc attttcttca
     4981 cgcaactgat ctagcaactt gtttgcaacc acgtttttgt ttggtatata agcattttta
     5041 tcgttgtttt gttcatgttt atgcaactta tctagcaacc tttgattgtc taagttgcga
     5101 gcaagttgca atactccaga acgcaataca accttataac cacgctcatt tttagctatc
     5161 atggaagaat ctaatttttg gatatgtttc gatattgctt gcctactcat cttaaaaaga
     5221 tctgacaatt cctttattgt aaaggtttct tgtggttgca tactggttgc ctcctaggtt
     5281 gctactggaa taaattatct aaatcagata ataaactttt tttctctttt tccgaaagtg
     5341 cggactctgt ttgtttttca agagcttttt tctctttttc tagttgtttg atttgttgga
     5401 ggagttcaag ttctcgtttc ttctgtttga ttttttcgtt aattgttgta gcgggttctt
     5461 cgtattcttt ttgtttatca gctaaagcca atgctttatt ttggtcttct ttggttggtg
     5521 catgtttgtt aaagtcgtct gcttttttga tctcaggttt gaacgtaaat tgatagccaa
     5581 taacaggttt tccccgtcct tttccgtatt tctttttgat tgttagtcct ttgaagattg
     5641 cagttagttc ttgacgtata ggttttataa ctcgtttatc tatatcaggt tgcttataac
     5701 ttttaggaat atctaataat tcaagaaagt cttctttgga gaaatatgcg aaacctttgg
     5761 ttctgtattg ctttaacaga cgaaacatag tctttgcata gccactttgt agctcgttga
     5821 attgttgtaa agaatagcgt acccactcgt ctaaattatt taacaaaggc agtgcttttt
     5881 cgtaaattcg tatatctacg taaggatttt ctacgtcccc gttgatttta aattctgtaa
     5941 acattacaaa catatcgtaa gaaagcccag actcacttct acgaccaaag cgtaaagata
     6001 agattttttc ataagttgct tttaaatctt ctacaaatcg tacatttgca gttgctttgt
     6061 agttacttaa atcttttagt tggtcaaacg taaaacgaac tgtcttatcc cctttttcac
     6121 gcattctaga cacgatgg
//
LOCUS       DAPBCF010000100         6133 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.104, whole genome shotgun sequence.
ACCESSION   DAPBCF010000100 DAPBCF010000000
VERSION     DAPBCF010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6133
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.104"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(207..1169)
                     /locus_tag="RD508_002746"
     CDS             complement(207..1169)
                     /locus_tag="RD508_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7737260.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="RD508_002747"
     CDS             complement(1171..2610)
                     /locus_tag="RD508_002747"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDT7737261.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="RD508_002748"
     CDS             2795..4741
                     /locus_tag="RD508_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HDT7737262.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..5877
                     /locus_tag="RD508_002749"
     CDS             5005..5877
                     /locus_tag="RD508_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7737263.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1946 a         1054 c         1084 g         2049 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggga ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc
     5281 atgaaaaaag aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat
     5341 ggtgagtatg tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt
     5401 acgggtgttg gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca
     5461 gaaatggggc atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca
     5521 tttcatggca actgtttaga agggatggcc gctggacccg ccatcgaaaa ccgcttaggg
     5581 aaaaaaggac aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt
     5641 gctcaatgtg cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt
     5701 ggtgtgatga aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc
     5761 aatgggtatg tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac
     5821 aacgctggaa cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg
     5881 aaaaaaggct cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat
     5941 aaccagttag gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat
     6001 gagataaatt cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt
     6061 gcaatagttt tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat
     6121 atatctttgc ttc
//
LOCUS       DAPBCF010000101         6124 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.105, whole genome shotgun sequence.
ACCESSION   DAPBCF010000101 DAPBCF010000000
VERSION     DAPBCF010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6124
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.105"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..855)
                     /locus_tag="RD508_002750"
     CDS             complement(<1..855)
                     /locus_tag="RD508_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HDT7737264.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIK
                     IIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLK
                     IHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHKIHEKLALKG
                     ITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSVKGLESRFES
                     ILLAYSVLL"
     gene            1071..1682
                     /locus_tag="RD508_002751"
     CDS             1071..1682
                     /locus_tag="RD508_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDT7737265.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            1755..2686
                     /locus_tag="RD508_002752"
                     /pseudo
     CDS             1755..2686
                     /locus_tag="RD508_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
     gene            2755..3581
                     /locus_tag="RD508_002753"
                     /pseudo
     CDS             2755..3581
                     /locus_tag="RD508_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033645.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
     gene            complement(3629..4807)
                     /locus_tag="RD508_002754"
     CDS             complement(3629..4807)
                     /locus_tag="RD508_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDT7737266.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKSFTEEVTSFKERELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERG
                     VKNVLLFITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKKAALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLASMFTE
                     "
     gene            4905..5003
                     /locus_tag="RD508_002755"
     CDS             4905..5003
                     /locus_tag="RD508_002755"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7737267.1"
                     /translation="MKERGLSGVKMVISDAHIGLTKAVKEYLLCAS"
     gene            5034..5435
                     /locus_tag="RD508_002756"
     CDS             5034..5435
                     /locus_tag="RD508_002756"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7737268.1"
                     /translation="MSDKFSKKISSDIKEDFKAIFKTASIELAGERKQLIMDKYGEDK
                     KVATACKILDEGFEDAMQVMVLPENIRQRLRTTNVLERLNEEVRRRERVVRIFPNCDS
                     VIRIIGALLMEKDDEWTSAPRKYLEFDRNEI"
     gene            complement(5642..>6124)
                     /locus_tag="RD508_002757"
     CDS             complement(5642..>6124)
                     /locus_tag="RD508_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7737269.1"
                     /translation="KEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKEQ
                     QVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFSN
                     NQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVIK
                     "
BASE COUNT         1911 a         1038 c         1170 g         2005 t
ORIGIN      
        1 taatagaaca ctgtaagcca gtaatatgct ttcaaatcta ctctctagcc ctttaacaga
       61 acgtgagttg aaattttgac aacctaattt ttctaaggaa gaaaaaacag tctcaactgt
      121 ttttctttgt tttccaagta agctgtggtc tagtttttct gatttatcca tgtttttacg
      181 tggcggaacg gatatagtaa tgcccttaag ggcaagcttt tcatggattt tatggctaat
      241 atatcctttg tcccctagga tattgggaag attcgcttct tccgataaag tctctaacac
      301 tttcacgtca tggacacctg gattcgtgat tgagtaagta atcggaaagc cagtcttagt
      361 aacgatcata tgaattttaa gaccataaaa ataagatttt tttgttgagt tatagccaac
      421 tttggctatt tgattcaata gttttgcttg tctatttcta actggtttac ataatggact
      481 aggaaaacta tctataattc cgactagttc acctttggtg agcttcttga tgaaaaagta
      541 tcgaataatc ttgatagtgt aagctaagtt tgaacttaag cgagtgaatc gactcctact
      601 aggaaagtca ccattaggaa ataagacgga acaaaccgct ctatacgtgg ctctttggct
      661 agtatagcca ttaattatgc cccatataac acaagcaata atcactgtat cgcgttgctt
      721 cagttgatca gtatttcttc ggtttttaat cttatctggt acacaattgt ggtatatgtt
      781 agaaacagtt ctcataattt ccttgaatgt tataaaagta tctgtataat gttcagtata
      841 ttttgatgaa cgcatatgta gtcctcattt cttgggagtt ttgagactac tatatgcgtt
      901 tttttgttga tttaccaaca tgtttagaca tttccctcta ggaaaaaatt aactagcacc
      961 acgggttatg atataataaa atgtattata ggcatttttt tacaagaaat agaagcttga
     1021 agtttatatg aagttataaa atttaattta tattggaagg aggaaaataa atgtatttta
     1081 tactacctac actttatagc cttttatgtg taatggcacc atgtattatt tatatggtat
     1141 ttttttgcaa aaaaaatacc ctgaaacaca atatcctgat tttgattttt atgctgtact
     1201 gttggaaagt ttttgaattg actggtacag gtggactaac agatattttt tatagacctg
     1261 atacaggtag gaaattttct ctagtacagg gcagtgttaa tcttgtacca ttcagtggac
     1321 taaacattag ctttatatta aatatagtaa tgtgtgtgcc cttaggattc ttactaccaa
     1381 tcatatggaa aagttatagg aaaatagttc ctgttttctt ggctggggct ctattttcac
     1441 taattattga agtctcacaa attataacta caagagcaac agatattgat gatttaatag
     1501 caaatacctt tggtgcggtt ataggcttta tactgtgggc tgttttaagt agagtggtgt
     1561 ccttgaagga caagtcatct acagtagatt atttagaacc ttatatttat atattgattg
     1621 gttttaccgg aaaattctta ctgtattttc ctttctggtt tgcttttgaa gtattatcct
     1681 gataattcca tagaaaataa tgagtttgag ttgagaaaga atattcttgt acacaactct
     1741 ggaaaggagg aagtatgaaa agattcttaa aatgggggct tgttctttta gcgtctttga
     1801 ttgtgattct aatgtgtaca gcggttgtta tttcttatgt gaatcggccg tatgcaagag
     1861 ctgtttatga taggattaaa cgcattcttg acaaagattt ttatgaccat ctatatctag
     1921 gttcttcatt tgaaataata aaccttgata caatggatat tcatagctat atgaaaaaag
     1981 accaagaaga attacccgcc tcattgagca aattatttac gattgattat gcgcttagtg
     2041 tcctaagttt agatgaacag attacaatta gtcctactgc acttgacatg cagaaagctg
     2101 actcatctac tgcacatctt caagaaggag atattttatc tgtttatgac attatctgtg
     2161 ctatggtctt accctcagga aatgatgcag cttatagttt ggcaatttat acaggtggaa
     2221 aactcttgat cctgatgcaa agaatgatga agaacgctat caaagcttca tgaaaaactt
     2281 agatcgttat ctaagtgagc aaggctataa acatactcat tttactgacg ctgctggcta
     2341 tgactccaat gctacaacat cagcggaaga tttgacaaaa gtagctgcaa agctactaaa
     2401 gaatgataaa tttgcagaaa tagttgccaa ggaaacttat agagcaaaat caattaaggg
     2461 aaatgtttat aactggaata ctacgaatca atttatgcaa caagataata gatactttac
     2521 tgaaggtgta aaaggtgtaa aaactggatc gtttgatggg agatacaatc tatgtgtgta
     2581 ttatacatct agttctgata accactattt acttgtaagt tttggttcag agagtgatag
     2641 taggcgttat gtagatgttc aaaatctatt gcataatctg ccttgaaatt tcgtgccttt
     2701 aagcgcgtat ctaaagtttc tttgaaaagt ttgagaatga agaaagtgag cagtcgaaaa
     2761 acggttgctc acttttttgc cctaaaatcg aaaaaatata aaaaagtcct ttacaacacg
     2821 tctcaggaaa aactgctaag tcaattctaa tatcttgtgg agcaagactt gcaccttttg
     2881 atataagaga gcttagagaa ctaatgagcg aagatgaact agaactcgat aaaattggag
     2941 atagaaaaac tgccttgttt gtaataatat cagatacaga tgatacattt aattttgtag
     3001 tttcaataat gtattctcaa ttatttaatc tactatgtga taaggcagat gatgtgtatg
     3061 gtggaagact tccagttcat gttaggtgtc tacttgatga gtttgcaaat atcggtttga
     3121 ttcctaaatt tgaaaaacta atagcgacaa ttcgttcaag agaaatatcg gcaagtataa
     3181 tactgcaagc acaatctcaa ttaaaagcaa tttataaaga ccatgcagat acaatagttg
     3241 gtaactgtga ctctacactt tttctaggag gaaaagaaaa aacaacagta aaagaattat
     3301 cagaaacctt aggaaaagaa accatagacc tatataacac atcagaaaca agatcaaatc
     3361 aaaaatcttt tggtctaaat tatcaaaaga ctggcaagga acttatgagt caagatgaaa
     3421 taactgtaat ggatggtggt aagtgtattt accagctaag aggagcaaga ccttttctat
     3481 ctgataaatt tgatattaca aagcataaga attacaaatt gttggaagat tatgataaga
     3541 aaaacttgtt tgatgtagaa gagtatttaa aacaaagata gcgtaaaata ttttgtgtaa
     3601 ataactcgtc cttctgcaaa ataatgggtt actcagtaaa cattgaagct aatgtatccg
     3661 tcacttgttg gaagccttta tggcttctat ttaagaattt ttgattgtat gtatcaaaga
     3721 tggatactag gaaacgctct agtgattctt cattttgaaa ctgctctttt ctgtggctgt
     3781 atttcttgat ttgcttatta aaggattcaa tcaagttcgt agagtaaata gtcttgcgta
     3841 tggctaatgg aaaatcatag aaagtgagca ggtaatcgtt cgaaaggatc gattccacca
     3901 tttttggata actggttttc catttttccg caaaagcacc acgtgcttcc aatgccgcct
     3961 ttttagatga cgcttgatac accattttaa aatcatcaca gacttcctta cgatcatcga
     4021 cacgcacttt gtgactgata ttacgggaaa cgtgcacaca gcaatgttga aaacgggctt
     4081 tggggtagaa ccgctgcacg gcccctgcca tcccctttaa gccatccgtg atgaaaagga
     4141 ggacgttttt cacgccacgt tcctggaggt ctattaaaat ctcttcccaa atcgtgatag
     4201 attcagttgg tgcaatcgca tagctcaaca cttcctttga accgtccggg cgaatgccaa
     4261 ctgcgatatg aatggcttcc ttggcgacgg ttttccgctt taaagggata taggttgcgt
     4321 ccatataaat agcggcataa cggtcatgaa gctcacgttc cttaaatgaa gtgacttctt
     4381 ccgtaaatga tttagtcata ttggacatgg tttggggcgt gtagtgatgc ccatacattt
     4441 tctcaatcaa gtctgcgatt tccgacatgg taataccttt tcggaagagg tgaatgacgg
     4501 tctcctctaa ggtatcattc gtccgtctat aagcaggaac agtctgttgc ttgaactcgc
     4561 cgttgcggtc gcgcggaatc tggagatgaa gttccccgta ctcggtcttg accgtacggt
     4621 cataggagcc gttacgagaa ttacccgtgt taaaaccaat gcgatcgtac ttttcgtaat
     4681 cgaggaaagc cgttaactcc gttttgagaa gcgtattgac agctttttcc aaatggacac
     4741 ggaataattc attcaaatcg cctttattcg ctagagtctt tagaatttct gtagtaaaat
     4801 cgttcatatg gaagtcctct tttctgtgaa tgtgttgtgg taactctatt ctactgaagg
     4861 gacttccttt tttctattta cacaaaatat tttacactct cggattgaaa gaacgcggtc
     4921 tttcaggagt aaagatggtc atctcggatg cgcatatagg gctcacaaaa gctgtgaaag
     4981 aataccttct ttgtgcgagc tagcagagat gccaagcaca tctccttcgc aacatttccg
     5041 acaaattctc caagaaaatc tcaagcgata tcaaagaaga ctttaaagcc atcttcaaaa
     5101 cggcaagcat cgagctggct ggagaacgta aacaacttat tatggataaa tatggggaag
     5161 acaagaaagt cgcaactgcc tgtaaaatat tggatgaggg cttcgaagat gccatgcaag
     5221 taatggtttt accagaaaat atccgtcaac gattgagaac aacgaatgtt cttgaaagac
     5281 taaatgaaga agtacgccgt cgtgaacgtg ttgtccgaat tttcccaaat tgtgattctg
     5341 ttattcgtat catcggtgct ttattgatgg aaaaggatga cgaatggact tctgcaccta
     5401 gaaaatatct tgaatttgat cgtaacgaga tttagcacat taagccgcca atagtataat
     5461 atactggtga gaagtatcaa gagacgcttc gctttttgct cttgacactt cttaccagca
     5521 tattggaccg tagctaggct caacaaggca aaacatcgta ctttgagatt tcctttttac
     5581 acaagatttt ggacttgaca cagcccctat ggttcttacc ttgtttatgc ttatttaaat
     5641 cttactttat tacagtactt tcaaacttcg ttttgtaagc cgggtatttt gatatttcat
     5701 aattatgtcc ctctttttga atatattctt tgatatctgc ttgttcatct acactttctt
     5761 tgcgtaaaat acgttcgatc attgagcagc agtgcatgta aagcaagaac aattgattgt
     5821 ttgaaaattc gatccccatt agtttttcga gttctttgac ggccttttgt accaatctca
     5881 aaaccttcat tgcatcaagg atcgttaaat tttctacgat cttgttaatc gagaaattaa
     5941 agtattgagc acaattatag gcgataaatg gagcatttga ttctatcacc tgttgttcct
     6001 tggcgtattc ataaattttt tctgccaaaa aggtttttcc tgaaccgctt acacccatca
     6061 ataaaatcgg taatccgtta tgaggataca agacagccgt cttgatttga tcgatcgctt
     6121 cctt
//
LOCUS       DAPBCF010000102         6114 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.106, whole genome shotgun sequence.
ACCESSION   DAPBCF010000102 DAPBCF010000000
VERSION     DAPBCF010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.106"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(125..772)
                     /locus_tag="RD508_002758"
     CDS             complement(125..772)
                     /locus_tag="RD508_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HDT7737270.1"
                     /translation="MEQTIKPYQYFFIIREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILDHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(1180..1683)
                     /locus_tag="RD508_002759"
     CDS             complement(1180..1683)
                     /locus_tag="RD508_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7737271.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1806..2570)
                     /locus_tag="RD508_002760"
     CDS             complement(1806..2570)
                     /locus_tag="RD508_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HDT7737272.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2678..2953
                     /locus_tag="RD508_002761"
     CDS             2678..2953
                     /locus_tag="RD508_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HDT7737273.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            complement(3154..3501)
                     /locus_tag="RD508_002762"
     CDS             complement(3154..3501)
                     /locus_tag="RD508_002762"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737274.1"
                     /translation="MIPSVSFLFKKLKTFFILPEIEESNELTASDRSAFLLPVFNTWG
                     KAPQKQPYRRCSKVSFLVLRQIYAKMWKAIFTKFSLILKTKRLFHNQSLMLDADQLFH
                     NLIDGVLSAASRY"
     gene            3669..4598
                     /gene="yidC"
                     /locus_tag="RD508_002763"
     CDS             3669..4598
                     /gene="yidC"
                     /locus_tag="RD508_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDT7737275.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQPKNSTNNKGRNAGKQQKRK"
     gene            4701..6049
                     /locus_tag="RD508_002764"
                     /pseudo
     CDS             4701..6049
                     /locus_tag="RD508_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
BASE COUNT         1901 a         1167 c         1123 g         1923 t
ORIGIN      
        1 aaggggctgt ccccagactt tagtaggcgt cattagctat ctttcgttag catttaaagg
       61 cgaacaccat cacctattca cttccattaa aagatagcat atttttctgt aaaaaacaat
      121 aaaattatcg ttctttcttt acacgttcag caaattcata gaaaggagcc aatttcgtta
      181 actgttgatt acattggtca ctatcatgac aaatataatt cccctttttc gtatacgtgc
      241 catcagaacc tgctttcgtt gtagaaagaa aaagcgaaac attcgatgtt ttctgacaga
      301 ttgcacagat tcccttattt atcgttggtg ataaagtacc gctaatccct tttaattttt
      361 catcttcgta atagaccatg aattttttct gcgtacctgg atcattccag ccgatgtacg
      421 tatgttcttg caagtcgatt tcattccaag ctggttgttt gagttttttc acttttcgga
      481 ataatttctc gatttgtggt ttgctaggct gcataaacgg ctgaacgatt tgcttcagct
      541 cctccaatgc tctttctgct tgcgcttttg tcagttttac gtctaaaact gtcgttaaaa
      601 atgtatcgat ttctggcagt tcgtgatcta atatgtctcg aatcttttca gctgctagtg
      661 cctgaactgt ttgtaccgtt tttggatcat tgacagatga gtacgcattt aataactgtt
      721 ctacttctct tattataaaa aaatattggt atggttttat tgtttgttcc atgattttaa
      781 agtcctttct tctaaccaaa gtgcatactt tgtagaaaaa agtgatcttc tgcaaagtat
      841 gtgttacctg aagatcctgg actcttttaa ataagatacg ttttgcatct tatcatcacc
      901 ccctttaatg cttattattc tatgtacatg attcattcga taaataaaag taaaccgtat
      961 cttgaacaga tagtcaactg caaacagaaa aaaggactgt gacaaaagtc gtgtcaaagt
     1021 cccttgtttc gaatgaatgg tgttcaaaag cttgcatctg cagtaataag ccgaaacttc
     1081 acaaaaattt gagaagtaat tttcgtaaat tccttcttat ttcttgaagc tgaccacttc
     1141 tgtcacaacc tcaatatggt ctattattgg ttttacctgt taaatcgagg attctttccc
     1201 aaagtaacgt tgccatctct tacgcatact tgcagacatg ggctgagccg cttctttgac
     1261 tgcgcagtat ttgtccacga atgtcacaat atatccttct ttatacttag gcggtgcgat
     1321 cgttgcaccc cacatgtgct tcaaaatgat atctcgctca agatccgaca aatcggtgat
     1381 tttttctgca ttctttacag caattcttgg atggatatac gcatgtgtcc cctcgtcaaa
     1441 tttcgtcgta cgccaatcat agtagaacag atcatgcaaa agtccagcac gcgctgttgc
     1501 tttagcattg ccaccccatt tttttgcgag cagataacta tagtaagaaa cactgatgga
     1561 atgctccaaa cgagtggaat gaacatgctg tgtgtaattc gctaattttt tcactgcttc
     1621 tgtttctaaa agatcttgta cataagacat atattcttcg tcttcacgcc atttttctgt
     1681 cataattatc gatctgccac ctttttgaat ttcattttct tctgaaattg atctaagtat
     1741 accaccagtg ttcggattat tctagtcgct ctagataaaa tagctaaagc ttaatagttc
     1801 cttaatcata aagaaaaatg ataaagaacg atccctgctg cgactccgac attcaatgat
     1861 tccgcatttc ctttcattgg gatatatacg ttctgatcag tcaaagacaa gatttcctga
     1921 ctgactccct gaccttcgtt tcccatgatt atagcgaaat cctctgtttt ttctactttg
     1981 tctaatgcat gtgcttcttc atttaattct gtaccgtaca ccgtaaaccc tttgcctttc
     2041 attacaggga ttacatctgc caaatctttt tgtaacacag gcaaatgata attgcttccc
     2101 tgcatgcttc gcagcacctt tgtactataa atatctgccg ttcctttacc taataaaaca
     2161 ccagccatac caaacgcatc tgccgtacgg atcatcgttc ccacatttcc aggatcctgt
     2221 acattatcta gtaaaagcca gcctcctgaa aaatctggcg tatcttcaga tgttaacgtc
     2281 atcactgcta agatcccttg cggtgtaggt agatctgaca tagcggtcat gacctcatct
     2341 gaaactagaa aagtagaaat ctctttgttt acagccagcc agtctcccca ttctttcata
     2401 cctctctgtg tcacaaaaag ttcttttatt tctgcatcag acgacgcagc ttcttcgatc
     2461 agatggaacc cttccaaaag atattctgcc ttttcttctc tgtatttctt tttatgtagt
     2521 ttttttaatt ctttgattct tggatttttt gctgattgga tctctttcac attccttcac
     2581 ctcacctgat tatatcatgg aataggtgct tgagcttgtt tcatcctaaa aaaatcggta
     2641 tcattgattt ataaaacagg aaagaaaggt gacgaacatg cgcaaagtta aaatgaatgt
     2701 ccaaggacgt gtccagggcg tgggatttcg ctatatgacc aagatggttg ctgatcagtt
     2761 aggcgtgacc ggaacggtaa aaaacgaaga cgacggctca gtcacaatcg aagcaatcgg
     2821 aaatgacgac atcatccaaa aatttatcga agaagtcaag aagtctccga gcccaagtgg
     2881 acgagtgcag tatgtggatg tccaagaaga tccgatgatt gaggaacgaa agaaatttga
     2941 tgtggtggga taaggttgtg aaaaggtcgc ttagttttga gtattaagga aaattttgtg
     3001 aaaatggctt tccacatttt tgcataaatt tgacttaata ccgagaaact gacttttgaa
     3061 caccgtcgat aaggttgttt ttgaagcgct ttgcctcgag tattaaggag aaacattttc
     3121 aaaatagctt ctcatatttt gaaatgtaat gacttaatac cgagaggcag ctgataaaac
     3181 accgtcaata aggttgtgaa aaagctggtc tgcatcaagc attaaggact ggttgtgaaa
     3241 aagtcgctta gttttgagta ttaaggaaaa ttttgtgaaa atggctttcc acatttttgc
     3301 ataaatttgt cttaatacca agaaactgac ttttgaacac cgtcgataag gttgtttttg
     3361 aggcgctttg ccccaagtat taaagacagg tagtaaaaaa gctgatctat cacttgcagt
     3421 gagttcattt gactcctcta tttcgggcag aataaaaaaa gtttttagtt ttttaaataa
     3481 gaaagaaaca cttggaatca ctcttttctt tccaagtatt tctttcttga ttttttgtct
     3541 tttttcaaaa tttttcgcta cgaaaaagaa agaatattta tatgaaattt ctatgaagtt
     3601 gattgaattc catgcgcttt tttagtatag ttaagtttgt gtaaaaatta tagaagagga
     3661 agtattctat gaataaatgg aaaaactggt tattgggatc cggacttgtc agtatcctgc
     3721 tctttttatc tggctgtgtg cggatggatt caaacggaaa ccctgacact tcaggaatcg
     3781 tttatcgagt actcgtccat cctatgggcc aagcgattac atatctagtt gagaatttca
     3841 attggtctta cggctgggca gttattgcaa tgactgtgat cgtccgtatc atcatcttgc
     3901 cactaggtat cagtcaatca aaaaaaacaa tgatccaatc tgaaaaaatg caagcgttaa
     3961 aaccacaagt tgaagcagca caacaaaaac taaaagctgc aacaacacgt gaagaacaaa
     4021 tggcagcaca agcagaaatg caacaagtat atcgcgaaaa cggattgagt atgaccggcg
     4081 gaatcggctg tctgcctcta ttgatccaaa tgccgatctt ctctgccttg tattttacgg
     4141 ctcgctacac agaaggtatc cgtgaatcat ctttttacgg catcgatcta ggctcaccaa
     4201 gtatggtgct tgttgccatt gcaggggtcg cttatctgct tcaaggatat atttcaacaa
     4261 tcggtattcc tgaagaacag aaaaagacga tgcgtacgat gctgatcgtc tctcctgcta
     4321 tgatcgtttt catgtcgatc agtgcgccag ccggtgttac actttactgg gtagtgggtg
     4381 gtgtgttcag ttgtctgcaa acattcatca caaacgttat gatgaaacca cgtttgaaag
     4441 cacaagtggc agaagagttg aaacaaaatc cgccaaaaca agtcgtcact ccaagaaaag
     4501 acgtgacaga atcggcaaag ccagctgaca ataaacaacc aaaaaacagt acaaacaaca
     4561 aaggccgcaa cgcaggaaag cagcaaaagc ggaaataaaa atatatgaca aaaaactgta
     4621 gacaaataaa aaaatttctt tgttctacag tttttttgtt acaatcaaag aaaacgtcgc
     4681 ttttcgagga ggaatgtata atgatgtcca aataatcaat ggatagtcga atggaagaag
     4741 ccaaaatttc gctagatgca cttgttccta aaaatcattt ggtccataaa attgacaaaa
     4801 tattgttatt tgattttatt tatccaattg ttgaatcaac ttactcgacc attggtcgtc
     4861 ctagcgttga tcctgtcatc ttagtaaaat tagtattcat tcaatattta tttaggattc
     4921 gttcgatgcg tcagtccatt aaagaagctg aaacaaacct agcttatcgt tggtttcttg
     4981 ggcttagttt aatcgataaa attcctcatt tttcaacgtt tggtaaaaac tatgtacggc
     5041 atttcagaga aaccgattgt ttgaacagat atttatcatt atccttgaac aagcagttga
     5101 agctagattt attcatgaag aaattttgta tatggattca acctatatta aagcgaatgc
     5161 gaaaaaacat atttttacaa gagaaatggt acataaataa gccattttat accaaaaaca
     5221 attgaaagaa aaaattaatg aagcaagaat tgcagaaggc aaacgtcctt ttggttcaat
     5281 cattcatcag gaggtggtag aagggaaaat tagtgtcgca gatccagaaa gtggttatta
     5341 tgtaaaaaca gaacaagaaa aacagtttgc ttattctgct cataccgttt gtgatgaaaa
     5401 tggttttgta ttagatgtca tgattacgcc tggaaatcta catgacagcc gaatgctcgt
     5461 gccacaaatc gaacgtgtta aatcatgttg tggtgtagct gctgatgctg cgtacaaaac
     5521 accttggaac gccaagtatt taatcgatcg aaaactacga cccatttttc cttatactcg
     5581 acccaaaaga agcaaagaac gttttaaaaa gaaagatttt tattatgatc cctattataa
     5641 ctggtaccta tgcccaaatg atcaaacact tcagtttcgc acaactactc gagatggtta
     5701 taaaaaatat gtatctaaat cttttatttg tgaaagttgt ctattattga aaaattatac
     5761 agaaagccag aaacaccaga aagaaataca tcgacatatt taggaagact acttagatga
     5821 agcagaacat ttacgccata cggtgtacaa tcgcgaaaaa tataaaaaaa agaaaagaaa
     5881 cgattgaacg cgtttttaca gacgcaaagg aaaagcatgg aatgcgctac accaaatatc
     5941 gaggcttgga aaaaaccagg tgcatacgat gcttgttttt gccgcaatga atctgcaaaa
     6001 attagccatt tggcagtggg ggcatatgtc tttatacccg tggtgctagt taattttttc
     6061 ctagaggaaa atgtctaaac atgttggtaa atcaacaaaa aaacgcatat agta
//
LOCUS       DAPBCF010000103         6011 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.107, whole genome shotgun sequence.
ACCESSION   DAPBCF010000103 DAPBCF010000000
VERSION     DAPBCF010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6011
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.107"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            641..1375
                     /locus_tag="RD508_002765"
     CDS             641..1375
                     /locus_tag="RD508_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7737276.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1391..2560
                     /locus_tag="RD508_002766"
     CDS             1391..2560
                     /locus_tag="RD508_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7737277.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2576..3571
                     /gene="lacD"
                     /locus_tag="RD508_002767"
     CDS             2576..3571
                     /gene="lacD"
                     /locus_tag="RD508_002767"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HDT7737278.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3650..4576
                     /locus_tag="RD508_002768"
     CDS             3650..4576
                     /locus_tag="RD508_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HDT7737279.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4595..5845
                     /locus_tag="RD508_002769"
     CDS             4595..5845
                     /locus_tag="RD508_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7737280.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDANRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2020 a          969 c         1217 g         1805 t
ORIGIN      
        1 gtttgaaaaa tgctatttcg aggtagaagg atattatata agcacggttg actaaacgaa
       61 gtgataataa aaaaagttat tcaagaataa gaaaaattat gatacgaatt cagataaact
      121 ggagaataca gagaccttta aaagggataa gaaacaacat aaattcctct taagagagaa
      181 cgaaaggaca aagccagcaa cttgatacac gagctagtat tagagaaatt tattctcata
      241 gactcccttt tgaatacgtt tcaactttaa ttttcatgtt cataaatgat ttgaaaccaa
      301 agcaaatgcg ttgcactttt cctccgtctt ccgaaaatcg ttcaattcac tggtaagtag
      361 tcatttgata gtttgaggca aattgttgat tgatgaaggg taggagctaa aaaaagatac
      421 cagttgaaga gagaaaaaga aaaaaataga gggtgttctt gaatgaaaaa agttggaaaa
      481 ttatttttca tttcctttta ttcctattaa attcagtgat gtcaatcata ttaacaagac
      541 taaaaatgaa aataaaaaaa agattgttct tagtattgac tcataaaaaa taccactact
      601 atacttacat tgtggttata gccagttagg agagacatcg atgcaaaata cctttcaatc
      661 aaaatcactt tattatcagc tggtagaaat attgaaacaa cgaatcgaaa acagtatggt
      721 cgctcatgac aagctgccat cagaaagaga gttgaccagt ttttatggcg ttagtcgcac
      781 gacggtgcga ctagcattgc aagaactgga aaaaatgggc tacatttatc gacaacatgg
      841 aaaaggaacc tttgtttcgg aattaaggac aaatgcgact gatctagctg gcgcatatag
      901 ttttaccgaa caaatgcggg caatgggcaa acatcctgaa accaagatat tggccttcaa
      961 gaagattgaa gcaactaaat atttagcgag tcatctgaat gttcaactag gtgagccttt
     1021 atttcaatta gaccgattgc gcttagctga tgatttgcca atgatgatcg agaaatccta
     1081 tttgccagtg aagctattta tgtccctttc tcaagaaatt ctatttctga aacctttata
     1141 taatttgttt tcagagaatt tcaatcaaat cgtacggttg gctgacgagg aattttatgc
     1201 cagcattgtc cagaaagaag atagtgagtt gctaaatatt ccagaaggat caccagtgct
     1261 ccatttagtt cgctcaacct ataatctcga gaacgaagtg attgaattta cattaagtgt
     1321 agcgcgggct gataaatttc attataagat caggcatctg cgttccacta actgaattgg
     1381 aggaaagaaa atgtttatgt tctcaaaaga agaactacga aagctaggag cagaaaatac
     1441 tacccgagaa attcgacaac aaccggaact gtggcatgag acgtttgacc gttatcaaga
     1501 aacagttgca gatttagatc gtttgtttac ggatgcgaaa caacatgctg gagagcgacc
     1561 aatccgagtc atttttacag gggccggaac ctcgcaatat gtgggagata cactaattcc
     1621 gtttcttact agtcaaggaa atacgaacca gtttattttt caaagtattg gttcgaccga
     1681 tatcgttgct acgccaaaag aatacctgat tcctgatgag acaacgatct tggtctcatt
     1741 tgcccgtagt ggaaatagtc cagaaagtct agccgcagtt aagatggcca atcagctggt
     1801 caacaagatc tatcatatcg tgatcacctg tgcaccagac ggattattgg ctacacaaat
     1861 gcctacaaaa aaagaaaatc tagttttact aatgccaaac aaagccaatg acgctggttt
     1921 tgctatgaca agcagtttca gctgtatgac gctgactgcg ctacttattt ttgatcaagc
     1981 aagcaatcag caaaaagaaa gatatgttca tcaattaagc cgactaggag aagaagtcat
     2041 ccaacgagaa tcagagatcc aagggtatct ggcatcagac tttcatcgca tcatttactt
     2101 aggttcggga agtttaggcg gattgactag agaagcgcaa ttaaaagttc tcgagttaac
     2161 tgctggaaaa atcgcaaccg tatttgatac atctttagga ttcagacatg gtcccaaatc
     2221 ttttgtcaat gagcaaacat tggttttcct gtttgtcagc aatgactcat atacgcagaa
     2281 atacgatgta gacatgctgg aagaaatcaa aaatgacggt attgcccaac gcgttgttgg
     2341 aattggtcaa aagggttcat tgtttagtgg tgattccttt gaattagttg cagattcgtt
     2401 actgccggat ggctatcttg ctttagcaga tatcatggta gcccaaacga tcgcattact
     2461 ttgttcggtg aaggttggta atacaccaga tacaccatcg ccaagtggaa cagtcaatcg
     2521 tgtggtcaaa ggcgtaacga tttatccata tgaaaaatag gaaagagtgt gaagcatgtt
     2581 agaatggtcg gaaaataaaa gacaagcaat ggaacgtcta tcgacgccag aaggcattat
     2641 taccgctttg gcgatcgatc agcgaggcgc gctgaagaaa atgatgtcgg ctttagggat
     2701 ggaagcgaca aaggaaaaaa ttgagcagtt taaaacacta atttcccaag aattgactcc
     2761 ttatgcctca gcaattttat tggatcctga atacggactg cctgctgcac agaagcgtgc
     2821 agcagcgagc ggtctgctgt tggcatatga aaaaactggt tatgatcaaa ccgtacccgg
     2881 ccgcttgccg gatctgctgt cggactgttc agttctgcga ttgaaagagt taggtgcgga
     2941 tgcggtgaaa tttttactgt attacgatta tgaagaagca gaggaaatca atcggcaaaa
     3001 gcaagttttt gttgaacgaa ttggaagcga atgcatggct gaaggactgc cattttattt
     3061 agagttattg tcatatgatg ctaaaaatgt agatacgaaa tcgctttcct atgccaaagc
     3121 aaaaccgcgc aaagtgatcg aaatgatgaa agaattctcg aaaacccagt ataaagtaga
     3181 tgtcttaaag gttgaagtac cagtaaacat gtcatttgtt gaaggaaatg caacagggga
     3241 gatcgcctat acacgtcaag aagctgccgc ttattttaaa gaacaaagcg atgcaacaga
     3301 tttgccgtat atcttcttaa gtgctggggt atcagcggca ttattcatgg agacattgcg
     3361 ttttgccaaa catgctgggg cacgattcaa cggtgtactc tgtggcagag caacttggaa
     3421 agatgcagtc gctccttttg ttgaaaaagg agaagcggca actttagaat ggctgacaga
     3481 acaagggaca caaaacattc gtcaattgaa tgaagtgata agagaaactg ccatcccatg
     3541 gtatgagaaa gtaagtgaaa gcacttgtta atgtttctaa tatattagta gtgataagag
     3601 atatgtgtga ttataattta tcattattga aactgggagg atattttata tgaataaaag
     3661 attgttagat tattcagctt cagatttttt gaaagctaag ccgatggaat taaagcaggc
     3721 aattttggct tctgaaggta gaacaattat ggcagaaaat gtgccaagta gctgtcctta
     3781 catgggaaaa tcagtgacaa atgcagaatt ggagagagct gctggagctg atttaatttt
     3841 gtttaatgca ctagatcttt ttaatcctca aatttcaggt gtacctttaa ctctaaaaga
     3901 gaatccaata atctggatta aaaaagcttt aggaagagct attggtgtaa atttagaacc
     3961 tgtagacaaa gaagttttga tgagtgaaaa tcgaactgaa atttcaagtg gtagaatcgt
     4021 ttctcctgag actttaaaaa aggcaaatga attaggcttt aattttattt gtttaactgg
     4081 aaatccagga acaggagtat ctaatagaac tattgagaaa gcaataacat tatccaaatc
     4141 aatttttaat ggattaatta tcgctggaaa aatgcatggt gctggtgttg atgaaccaat
     4201 tatgaactta gatatagcaa aaagatttat taaaacaggt gtagatattt tattagttcc
     4261 tgctccatac actgttccgt atttcatgga aagtgatttg cgaggaatcg ttgattatat
     4321 aaaagatttt aatagaaata aatctattga ggaaaaagtt ctagtactaa cggctaatgg
     4381 aacaagccaa gactcttctg accaagaaac tattaaaaaa attgcattag catcaaaagc
     4441 atgtggagct gatattcaac acatagggga ttctttaaat ggtatttgtc ttccagaaaa
     4501 tatttttgct ttgggtcaag caattcgggg atatcgtcat caaattatta tgttaggaaa
     4561 atctaattat cgttaattaa ggaggaaatg aaagatgatc gacaaagttc aaaaaatagc
     4621 tgcaaaaatt agtaatcaaa gacatctact agctttaaga gacagcatgg ctgcagttat
     4681 gccattaatc attattggtt ccttttttat gttattagca aatttcccga tagaaggatt
     4741 tacaaaatgg ttatctgaaa ttggagtaca atcctttttg aacaaagcat cagattcaac
     4801 atttggtatt attggattag ctgttaccta ctctttggga cacaatctag caaagactta
     4861 tggtgtagac tcattatcag caggattatt atctttgagt ggatatgttt tacttacacc
     4921 tttattggat gcagatggtt ctataggatt tccaacaaaa tactttggta cctcgggtct
     4981 ttttgttggt attattgtag cacttgtatc tacagaaatt ttccggtggt ttgtacttaa
     5041 aaatattaca attaaaatgc cggcaagcgt tccaccaaat gtaagccgag ctttcgttgc
     5101 tattattcct ggcttttttg tcgttctact atggtttatt gttgttgtaa tttgttataa
     5161 acttggaatt gaaaatgttc atgctcttat tgcagataca ctcgcaaaac cactatcttt
     5221 actgacgaaa actttaccag gaattatatt ggttatactt attcaatgtt tcttttggat
     5281 gtttggtatt catggtgcac aggtaacggg gccaataatt gaaccgttat tattgcaaaa
     5341 ctctgatgca aatagaattg cttatcaagc tggaaaagaa cttcctaaca ttataactta
     5401 tgaattctta tataactttg ttttttctgg tggtgcaggt tgtttatttg cacttgccat
     5461 tttaacattt ttcttttcaa agagtcagga aaataaaact ttaggtaagt tatcaatcgc
     5521 tccagtaagt tttcaagtag cagagcccct tctatttggg tttccaacta tattaaatat
     5581 aaaaatgtta attccatttg taactgcacc agtagtaaca acattaatta cttatttttc
     5641 aatgagtatg ggattagttg caaaacctgt aggagcaaca atcccatgga caactccacc
     5701 gataattgcc ggatttttag cttctggtgg acgaataagt ggtgcagtga ttcaagtaat
     5761 aacaattgca ataaatgttt tgatatacta tccattcttt aaattagatg ataatgccaa
     5821 gctaaaaagc gaaaaaaatg attagaacta cctatatgtt tctaactgta gttaagtatg
     5881 aaaagactat ttttaaattt agcatttttg cgctatcggc gtagatgaag tatcacgata
     5941 acgaaattag tttctttcat ttagaattaa aaaatcaact taaatttttt ctgaaaaata
     6001 ttaatatctt a
//
LOCUS       DAPBCF010000104         5911 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.108, whole genome shotgun sequence.
ACCESSION   DAPBCF010000104 DAPBCF010000000
VERSION     DAPBCF010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.108"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(368..1486)
                     /locus_tag="RD508_002770"
     CDS             complement(368..1486)
                     /locus_tag="RD508_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737281.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1957..3264
                     /locus_tag="RD508_002771"
     CDS             1957..3264
                     /locus_tag="RD508_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDT7737282.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3383..4582
                     /locus_tag="RD508_002772"
     CDS             3383..4582
                     /locus_tag="RD508_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDT7737283.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4609..5877)
                     /locus_tag="RD508_002773"
     CDS             complement(4609..5877)
                     /locus_tag="RD508_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HDT7737284.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
BASE COUNT         1815 a         1252 c         1058 g         1786 t
ORIGIN      
        1 tttttaaacg gtgttccaga agtagcttct tcggaaataa gccgaaattt cacaaaaatt
       61 tgagaaataa tttttgtcaa tctcttctta tttcttgaag ctgaccactt ctgtcacaac
      121 ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagcccac caaacaaaaa
      181 atatgaagag ctatttttgc ttgctgttct tattacttga tgcagaacag ctttttcaca
      241 acctctcata cacggtgttt aatcagctga ccttcggtat tagctcaaaa aacggaaaaa
      301 tatgtgaaac tatttttccg tttgtttctc taatactcag gtcaaaacac tgatttcaca
      361 acctctttta ataacgaaga atcgctgtca gactcttttc atctggcgca tctttttgat
      421 ccaaaataaa cactttcccg ccattaatga tcacatcatc tgctaatgca ttcaacactt
      481 gacgccgatc atattctgtt tcaggatctt caccgaaacc atcagctaag tttgacgtag
      541 cgataaataa atgtgacact tttccttctt tcgcagctgg aacgatatca actaactgat
      601 cgatgaattt cttatctaag agtttattgt attcttttga ttcttgagct gcgagttcac
      661 ttgacagctt cttcgcccct tcttcgatat ctctaaagga tagctgcgca ggagaagcag
      721 aaatcgcaac gtctgcacaa taatagggat ttttagcaat ttttttgaac atcgtctgat
      781 tttctggtaa tgcaaataaa taaatcggcc attgttcagg attttcgaaa gaatccttca
      841 agtacgtatc aacagcttgg taatagttga cccaatcgat ctctacttct tcatcttttg
      901 gatttacgcc atggaaagtt actccatctc gggctccgcc tcctccatta gaagagaagt
      961 tcaaaccgcc acctgtcagt tcagatccca atgcagtaac gacatcaacc ggtgcccctt
     1021 ctggtagaga tacttctttt acttgtttgt tgctgacctc atacaatttc atggagtcgc
     1081 ggttcaatcc caataaataa taagaatagt tgaactgccc atttttgata atagccagta
     1141 aataaggaag atcacttaca tagtattgat cgtctaccgg gatactcaaa cgatggatat
     1201 aggtctggtc agcagttata atgaccgcta cactcgtagt tgcactacgc caaaacgaag
     1261 gatctcctaa caaattttca attttttctt ggaacgggga ccagtcatgt tcggaatatt
     1321 ttttctcaaa acgtttcttt gcttctttcg caaaattttt gaatttgatc tgatcttttt
     1381 ccacatcttg atgggcgaca tgcgtattca gcatgatcgt gacgaatggt cctttagcgc
     1441 cttctgaagt caattgtgtc aataattctt tatccttttt tgccataaac gtacccctcc
     1501 taaaaaaatc attcctttgt ttctatctaa agtctaccac aacactattt ttccatacaa
     1561 taaaacgtat ctaaaaaaat aaaacggttt ctacggtttt aaatttagct atttttttaa
     1621 gttatcttca taatttcctc aattatttag ccccagtctt caactattct tcatgaaatg
     1681 ctgataaact aagaaaaaga ataaaagagg tggatcttat gcatttgatt atgattttca
     1741 gtttattaag tattatcagt ttatttgctt tcagcgcttc ccgcttatta gatgcggaaa
     1801 cacagcctat tcctgtaaaa gtacgtaaaa acgaccgcta aacttccata acgcgcgttc
     1861 ttatcctaaa gttttttcag aaacattgaa actctctccc ctctctgata aaattttaat
     1921 ttgtagcgaa acaaattaat tacaaggaga tcggatatgt ccataaaaaa aacacgtcta
     1981 gtcctattat tggctagtct cattctttgc cttgcttctt ttctaccagc tgttgctgtg
     2041 caagctgaag atacgttcaa agtaaatgca aaagcagctt ttgctgtaga tgcgcaaagc
     2101 ggtaagattc tttatgatca agatggagaa aaaaccatgg ggatcgcttc aatcacaaaa
     2161 atcatcggtc tttacatcgt ccttgatcaa gtaaaagaag gaaaactgtc atggggtgat
     2221 aaagtttcga tttcagatta tgcagaaaat ttgagtatca ccccagattt atcgaatgtt
     2281 cctttgcata aagaaaacac ctacactgtc aaagaattat tcgactctgc aatcatccag
     2341 tcagccaatg cttcaatggt ggccttggca gaaaaaatct ctggcagcga agctaaattc
     2401 actgaacgaa tgaaagaaca attgaaagat tggggaatca aagatgcaac aatcgttaat
     2461 gcatcaggat tgaacaactc ttatcttggc gaaaaccgac cagaaggcac tggagaaaac
     2521 gacgaaaatc aaatgtctgc tcaagatgtg gccatcgttg cccgccattt gatcttggat
     2581 ttcccagaaa tactggatgt atcaagtact acgacccaaa tgtttggcga aaatacgcaa
     2641 tcaccagtgg aaatggtcaa ctggaactgg atgctcccag gattcgttaa ttacaaggaa
     2701 ggcgtggacg gattaaaaac tggtacgact gagcttgcag gtgcttgttt cgttggtacg
     2761 atcactaaaa acgatcaacg gatcatcact gtcgtattga atgcggacgg ccatgcggaa
     2821 aacccgagtg cccgcttcaa tgaaacagac cgtttgatgg actactgcta tgacaattgg
     2881 tcagaaaaag agctcggaaa agctaacgca agtattccta gtctaaaaac cattgatgta
     2941 aaagacggaa aagaatcaac agttcctgtt gtgcttaaaa gccctgtaaa agtatgggta
     3001 cgaaacgata tggatactgg caaattaacg atcacgccaa cacttgacaa gaagcaagtc
     3061 actgacaatg agatccaagc acctatggat aaaggtacaa aaatcggtac cgctacgatc
     3121 accttggcag acgataaatt aggctattta gaagacaaca atgcaccatc aacagagatc
     3181 attacggata aaacagtgga aaaagcgaat atattcgtga ttggctggcg acgcgtcgca
     3241 gaatttttcg gcaacttgtt ttaattgaac aataagaaaa acatctttcc atcggaaaga
     3301 tgtttttttg ctttttctag tttaaataac agcttttttc atctattttc gttatactgt
     3361 ataagaaaaa ggagttgaat ttatgaatct aaccagagat ctgatctttt tagttctcta
     3421 tcttattggg gtattctcta tcgtttattg gcgaaaacag aagaaggatc cttccttgtt
     3481 cttttacggc agtacgtgga catttacggt aatcttaact tattttgtcg tgttggaaat
     3541 tttttattcg accttttatt ttttgattcc attgttgttc tttagtatct ttgctttttc
     3601 ttatttcaca gaaaaacgaa ggctactgaa tggtctttta ttcaatgttt tactcatcag
     3661 tttcggcatc tacttgtttg tcttgctgta tgaaacgcaa aatatttttc ttggcggact
     3721 gatcgccttg atcacgattc cattgctact tgtcctttta tttggtattt atggattgat
     3781 tgtttttctt ttttggaacg gggtcacagt tttacgtaga gaatcgcatt cattagctaa
     3841 tcttttaacg ttgatactag ccatttttct tacactgttt cttgtttttg actttttctt
     3901 gttaaaatat ttgccgcaat ggataaatgc tttgtttttc tgcgttcccc tgatcttgat
     3961 ctatctattt atcgtattct acaacttttt gactgtctca ttcttgtatc agttcaaccg
     4021 gcctcgatac aatcaagact tcatcgttgt gttaggcgct ggattgatca atggagaaac
     4081 agtttctcct cttctagcca agcgaatcaa taaggcaatt gctttttatc gggctcaaag
     4141 ccgtgctaca ttaaatccgc ccatcttatt gatgtctggc gggcaaggag cagacgaaaa
     4201 agtaccagag gccattgcga tgaaacaata tgccatggaa caaggaatcc ctgaaagaga
     4261 cattcttgtc gaaaccaatt cgacaaccac tttggaaaac atgctctatt caaaggaaat
     4321 catggatcag caaatgaaag ggccataccg cgcgatcttt agttccaaca attaccacat
     4381 ttttagagcc ggtctttatg cgcggcaagc caaattgaaa gcaaatggta ttggtgcaaa
     4441 aacagctttc tactacttgc ctaatgcgtt tttaagagaa tacctcgcca tcttgatgat
     4501 gaacaaaaaa agacatatga tcatttgcgg attgcttttc gcaggctccg cattcttatc
     4561 gctgattact ttacttttct aaaaaaacaa ggtgtgacaa aacatatgtc acaccttgtt
     4621 tttttctttc attctcttaa ctattggcaa aaagagtatc ccttttttga ccgctacttg
     4681 ctgagcagaa taaataccgc tgttgcctga acacataaag ctgatcaagc agatcataaa
     4741 gaagtatact gccgcttgtg aaccgaacaa ttcgatcccc atcacaaagc aggcaatcgg
     4801 tgtatttgtc gcaccagaaa atactccgat aaagcccaat cctgcaagaa aaggaacaga
     4861 aacatggagc aaaggcgcta gtgctgcacc aagcgttgca ccaatttcaa acaatggtgt
     4921 cacttctccc ccttgatatc ccgcgcctaa agacaaaact gtgaagaata acttcccaat
     4981 aaaatcatag acatgtgcct gtccattaaa tgattcttga agtaacggaa gactcaatcc
     5041 gagataacgt tgtgtttgca aaatcaatgc tgctgccaca actacagctc cacctatcgt
     5101 atttcgacaa acaggatgag gaatccattg tgcatatcgc gcttttaaaa agacgatcga
     5161 acggctgaat acccaaccaa tcaaaccaaa agcaatccca gcaacaaaaa ctttgaagaa
     5221 cagcaacata ctccattcag gaatcacacc catttggtaa tgtagatgag aaacaccata
     5281 gctttctgtc atgaaatttg caaacagtgc agcaaagaag ctagggaaga tcgcttctgt
     5341 tcggactttc ccgattgcca acacttctaa tccaaataat gttccagcta aaggtgtgcc
     5401 aaatacagaa ctaaaacccg cactgattcc actgataatc aagatttccc gttctgattt
     5461 atccaatcgg aacaaacgtg ccgtattatc tgctaacgct ccccccattt ggactgctgt
     5521 tccttcacgg ccaacagatc ccccaaataa atgggtagtt atggttccaa acagtgtaag
     5581 tggaataagc cgcaacggga ttttttcttc tccaccattt ccttgatcga tcactaagtt
     5641 gtttccacga ctagaaagtc cgccgtgata cgcatagaga taagcaaaaa gcgcaccact
     5701 aactggtagt agacaaagga gccaaggatg tgatagtcgg atatctgtca caactgtcag
     5761 gctatttaag aaaaaagcag acaagctccc catgaatata ccgagaatcg ctgtgatcac
     5821 cagccacttc agcatataca ctaaaatgcg tactggactc ggtaattgtt tttccataaa
     5881 aaattcctcc tcaataaaaa aacgcctact a
//
LOCUS       DAPBCF010000105         5836 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.109, whole genome shotgun sequence.
ACCESSION   DAPBCF010000105 DAPBCF010000000
VERSION     DAPBCF010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5836
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.109"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(336..1112)
                     /locus_tag="RD508_002774"
     CDS             complement(336..1112)
                     /locus_tag="RD508_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDT7737285.1"
                     /translation="MIGFIYFIVIVLANTVGAVSGMGGGVLIKPIFDFIGAHSVAAIS
                     FYSTVAVFTMSLVSTARQLASGRKIHWQIVLWVSGGAVLGGILGNVAFDHLLLLFQNE
                     DEVQMIQIFLTVVTLLFAFFYTKYDWPGFQLKNNFWYCFCGLVLGFLASLLGIGGGPI
                     NVSLLMLMFALPIKEATVYSICTIFFSQLAKIVTIAGTTGFGLYDLKILWFVIPAAIV
                     GGLLGAKVSTVLSPQKVTLVFQTVIFLVLIINLYNGYQLL"
     gene            complement(1109..2221)
                     /locus_tag="RD508_002775"
     CDS             complement(1109..2221)
                     /locus_tag="RD508_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPASM domain-containing protein"
                     /protein_id="HDT7737286.1"
                     /translation="MKHISVLIKPASSLCNLRCSYCFYANVSSLREVRSFGKMKEEVT
                     EKMIENIYADLEDGDQLTLAFQGGEPTMAGLNYFRTVIRLVAQQQKQVQVHYAIQTNG
                     TMINEKWCAFLKEHDFLVGLSIDGHPLYHDLHRVDPKGRGTFQRVLQTKQLFDYYEID
                     YNVLCVLTNPLAKEAKKVFRFLKEQQIDFVQFIPCLDDLDAKKRNSYALTPKRFAGFY
                     HQLLQLWLQELAEGHYISIKLFDDLLNLLIKRQVTACGILGNCQVQYVIEADGSVYPC
                     DFYVLDEYRMGYIQEQTLRQLFEQDIAKTFLCGRPEMPKKCLSCPFQKMCRGGCKRMK
                     DAIYVDNTGYCGYQQLLQEFVPQINRILGLLQGVSV"
     gene            complement(2302..3006)
                     /locus_tag="RD508_002776"
     CDS             complement(2302..3006)
                     /locus_tag="RD508_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7737287.1"
                     /translation="MIKPKYLEIKQNLKQQIVTGQFHNGDRFYSESEIIKKYNVSSIT
                     AIRALKELVAEGYIVRYQGIGTFVSRARKEKIVKFSDIEIFSFDNDKTHVLSIKRENK
                     KQILDTLKLSTDSYYYQIERIREANEIPYIYHKSYLPEQYINSNYPEINYYNSIYKRL
                     KSDYNIDLNEENFRETNEILFPAPNSVCKQLKINESEPVVFQTKLSCLSENNKPIEYV
                     ESYKKWNFYKIQLLSN"
     gene            3126..4904
                     /locus_tag="RD508_002777"
     CDS             3126..4904
                     /locus_tag="RD508_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HDT7737288.1"
                     /translation="MTTFEIKEEFLLKGKTFKILSGAIHYFRIPPCDWEHSLYNLKAL
                     GFNTVETYVPWNLHEPQKGEFHFEGILDLERFLTIAQDLGLYAIVRPSPYICAEWEFG
                     GFPSWLLREPIHIRRNEIAYLEHVADYYDVLMKRIVPHQLNNGGNILMIQIENEYGSF
                     GEEKEYLRAIRDLMIKRGVTVPFFTSDGPWRATLRAGSMIEDDILVTGNFGSKAKDNF
                     NSMKQFFKEYDKNWPLMCMEFWDGWFNRWKEPIIQRDPQELAEAVKEVLEQGSINLYM
                     FHGGTNFGFMNGCSARGVIDLPQITSYDYGAPLDEQGNPTEKYYALRKMIHDNYPEIK
                     QLDPVIKPTIEKKKISLTNKVSLFATLDTISQPVQSKYPKTMEELGQNTGYLLYRTMI
                     ERDAEEERLRVIDGRDRSQLFLNQELQATQYQTEIGEDIQVSMTEEINQVDILIENMG
                     RVNYGHKLFAETQKKGIRTGVMADLHFITNWQQYSLPLENCKTVDYSKGWQPQHPSFY
                     RYEFLLEDIGDCFIDLRKFGKGIVFVNQTNIGRFWEVGPTLSLYISSGFLKVGKNEIV
                     IFETEGTYEPEINLLKAPLYKEMKEG"
     gene            4908..5387
                     /locus_tag="RD508_002778"
     CDS             4908..5387
                     /locus_tag="RD508_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HDT7737289.1"
                     /translation="MSIIGVRIDGRLIHGQVANLWTTKLNISRIMVVDDEVAQNDIEK
                     SGLKLATPAGVKLSILPIEKAAQNILAGKYDSQRLLIIARKPDRLLKLVELGVPIKEI
                     NVGNMSQTSETRSITKSINVVDQDVETFNQLNEKGVHLIAQMVPSDKADDFMSLLNK"
     gene            5410..5817
                     /locus_tag="RD508_002779"
     CDS             5410..5817
                     /locus_tag="RD508_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDT7737290.1"
                     /translation="MAGHLVLISHGRFCEELKRSVDMIMGVQKDIYTVGLLPEESAKD
                     FRVNFEKTINGLKKVTVLADLMGGTPCNVVSQLILEGKEIELYAGMNMPMVIGFVNNQ
                     FLGEDSSLVNKGRENIIHVNEYLEVNPIDLEDE"
BASE COUNT         1967 a          945 c         1143 g         1781 t
ORIGIN      
        1 atgagaatta gaatcttttt gatcaatcaa ttaatcaatg taagataaca aaaaatctga
       61 gccagaatgt ggttcattct gacccagatt tgattttgca caactcatca gtccttattg
      121 acaaagagcc tattttgtta gtagatgtct ggaaacggta ctttgcacat ggtgaacagg
      181 cagtgctatt agaaaaatca tgcatattac taatgcaatt gagagtattt attctagttt
      241 cagaaaagtc acaaaaaaga gcgcttctta atgagaaagt acttctaaag ttactaatta
      301 atcgttttct ataagtggtt gataatactc gttttttata gtaattgata gccgttataa
      361 agattgatga ttagcaccaa gaagatgact gtctggaaga ccagcgtcac tttttgtggt
      421 gagaggacag tgctgacttt tgcccctaac aaaccgccaa caatcgcggc tggaatcaca
      481 aaccacaaaa tctttaagtc atagaggcca aatccagtgg tcccagcaat cgtcacgatt
      541 ttcgccaatt gagagaaaaa aatcgtacaa atcgaataga ccgtggcttc tttgatgggt
      601 aaagcaaaca tcagcatcag caaggacaca ttgatcggtc caccgccaat gcccagcaga
      661 ctcgctagaa aaccaaggac taggccacag aagcaatacc agaagttatt tttcagttgg
      721 aatccgggcc agtcgtattt ggtataaaag aaagcaaaca gcagtgtcac aacggtcaaa
      781 aagatctgaa tcatttgtac ctcatcttca ttctgaaata aaagcagcag gtgatcaaaa
      841 gcgacattgc ccaagatgcc tcctaagacg gcgccgcctg aaacccaaag gacgatttgc
      901 caatggattt tacgtccact agccaactgt cttgcggtcg aaaccagcga catggtaaac
      961 acggctacgg tagaataaaa cgagatggct gcaacagaat gggcaccgat aaaatcaaaa
     1021 atgggtttga tcagaacacc gccccccatg cctgaaacgg caccaaccgt attcgccaac
     1081 acgatcacta taaaataaat gaacccaatc acacacttac cccctgtaac aaacctaaaa
     1141 tccgattaat ctgcggtaca aattcctgca aaagttgctg ataaccacaa tagcctgtgt
     1201 tatctacata gatggcatct ttcatccgtt tgcagccgcc acgacacatt ttttgaaacg
     1261 ggcaactcag acatttcttt ggcatttcgg ggcgtccaca caaaaacgtt tttgcaatgt
     1321 cctgttcaaa taactgacgt aaagtctgtt cttgaatata ccccatgcga tactcatcca
     1381 gcacataaaa atcacaagga tacacactgc catctgcttc aatgacatat tgtacctgac
     1441 agtttcctaa aatcccgcag gcagtgactt gtcgcttgat caatagattc aaaagatcat
     1501 caaaaagctt gatacttata taatgcccct ccgctaattc ttgcagccat aactgcaaaa
     1561 gctggtggta aaatcctgca aaacgttttg gtgtgagagc ataactattt cttttttttg
     1621 catctagatc atctaaacaa ggaataaact ggacaaaatc aatttgttgc tcttttagaa
     1681 agcgaaagac tttcttagcc tcttttgcca acggattggt caagacacaa agtacattgt
     1741 agtcgatctc atagtagtca aacagctgtt ttgtttgcag cactcgctga aaagttcctc
     1801 ttcctttcgg atcgacccga tgcagatcat ggtagagcgg atggccatcg atcgagagac
     1861 cgaccaaaaa atcatgttct ttcaaaaaag cacaccattt ttcattgatc atggtcccat
     1921 tcgtttgaat cgcataatgg acctgtacct gcttttgttg ttgcgctact aaccggatca
     1981 ctgtacgaaa ataattgagg cccgccatcg ttggctctcc accttgaaac gctaatgtta
     2041 attgatcgcc gtcttctaag tctgcataaa tattttcgat cattttctct gtcacttctt
     2101 ctttcatttt gccaaacgag cggacttctc gcaaggaact gacattggca taaaagcagt
     2161 agctgcagcg aagattgcag agggaagatg cgggtttgat caatactgaa atatgtttca
     2221 tagtaagaac ctcatttttt aacatagttt aattatgaaa aattgctata acgaacaaag
     2281 taaaatcaaa ttcagtagta gttaattaga taggagttga atcttataga aattccattt
     2341 tttataactt tcaacatatt ctataggttt attattttca gataagcagg ataatttggt
     2401 ttgaaaaacg acaggctcag attcatttat ttttagttgt ttacatacac tattaggagc
     2461 aggaaataaa atttcgtttg tttccctaaa gttttcttcg tttaaatcaa tgttgtagtc
     2521 tgattttaaa cgtttgtaaa tagaattgta ataattaatt tctggataat tagaatttat
     2581 atattgttct ggcaaataag atttatgata gatataaggt atttcattag cttctctaat
     2641 tcgttcgatt tgataataat atgaatcagt tgataatttt aatgtatcta atatttgttt
     2701 tttattttcg cgtttaatcg aaagaacgtg tgttttatca ttgtcaaatg aaaatatttc
     2761 tatatcagaa aattttacta ttttttcttt tcttgcacgt gaaacgaaag ttcctattcc
     2821 ttgataacgt acgatatacc cctcggcaac taattctttt aacgcacgaa ttgctgttat
     2881 agaactaaca ttatattttt tgataatttc tgattctgaa tagaatcggt cgccattatg
     2941 aaattgaccg gttacaattt gttgttttag attctgtttg atttctagat atttcggttt
     3001 tattataagc tcccccttta aattactcgc atctatatta acatacttaa aaaaaaattg
     3061 ttgactttta atacaaaagc attaatatac taagtatatt aacacattga ggtgaaaagt
     3121 aacagatgac tacatttgaa ataaaggaag aatttttatt aaagggaaaa acatttaaaa
     3181 tactatctgg tgcaattcat tattttcgga ttcccccatg tgattgggaa cattctttgt
     3241 acaatttaaa agcactagga tttaatacag tagagacata tgttccttgg aatttacatg
     3301 agcctcaaaa aggagagttt cattttgaag ggatattgga tttagagaga tttttgacaa
     3361 tcgctcaaga cttaggatta tatgctattg tgcggccatc gccttatatt tgtgctgaat
     3421 gggaatttgg agggtttccg tcatggctac tccgtgaacc gattcatatc cgaaggaatg
     3481 aaatcgctta tttggagcat gtagcagatt attatgatgt tttgatgaaa aggattgttc
     3541 cccatcaact taataatggg ggaaatatat tgatgattca aattgaaaat gagtatggat
     3601 cttttgggga agaaaaggaa tatttgcgtg cgataagaga tttgatgatt aagcgaggag
     3661 tgacagttcc ttttttcact tcagatggac cgtggagggc tactttacga gcgggaagca
     3721 tgattgaaga tgatattttg gttactggta attttggttc taaagcaaaa gacaacttca
     3781 actctatgaa gcagtttttt aaagaatatg ataaaaattg gccactgatg tgtatggaat
     3841 tttgggatgg ttggtttaat cgttggaaag aaccaattat tcaacgagat ccacaggaac
     3901 tcgctgaagc ggtaaaagag gtattagaac aaggaagcat taatttatat atgtttcatg
     3961 gaggaacgaa ttttgggttt atgaatggtt gttcagcaag aggagtgatt gatttaccgc
     4021 aaattacttc ctatgattat ggtgcaccat tagatgagca ggggaatcca acagaaaaat
     4081 attatgcatt gcggaaaatg attcatgata attatccaga gattaagcag ctagatcctg
     4141 tcattaaacc cacgattgaa aagaaaaaga tttctttgac gaataaggta agtcttttcg
     4201 cgactttaga taccattagt caaccggttc aatcaaagta tccaaagaca atggaagagt
     4261 tgggacaaaa tacaggttat ctactttacc gaacaatgat agagagggat gcagaggaag
     4321 aacgattacg ggtaattgat ggcagagatc gcagccaatt atttttgaat caagaattac
     4381 aagctaccca atatcaaaca gaaataggtg aagatataca agttagtatg acagaagaaa
     4441 tcaatcaagt ggatattttg attgaaaata tgggacgtgt caattatgga cataaactct
     4501 ttgcggaaac gcaaaaaaaa ggaattagaa cgggagtaat ggcagactta cattttatta
     4561 caaattggca acagtattca ttgcctttgg aaaattgtaa aactgtggat tattcaaaag
     4621 gatggcagcc ccaacaccca agtttttatc gatatgagtt tcttttagag gatatcggtg
     4681 attgttttat tgatttaagg aaatttggta aaggaattgt ctttgttaat cagaccaata
     4741 taggtcgttt ttgggaagta ggtccaacgc tttcactgta catctctagc ggctttctaa
     4801 aagttggtaa gaatgaaatt gttatttttg agacagaagg tacctatgaa ccagaaatca
     4861 atttattaaa agcaccatta tataaagaaa tgaaagaggg atgaacaatg agtattattg
     4921 gagtaagaat tgatggacgt ttaattcacg gacaggtagc caatttatgg acaaccaaat
     4981 tgaatatttc tcgaattatg gttgtggatg atgaagtggc tcaaaatgat attgaaaaaa
     5041 gcggattgaa attggctacc ccagcagggg tgaaactaag tattttgccg attgaaaaag
     5101 cggcgcaaaa cattttagca ggaaaatatg attcacaacg tttactgatt attgcacgaa
     5161 aacctgatcg attattaaaa ttggtagaat tgggcgttcc aataaaagag attaatgttg
     5221 gaaatatgtc acaaacttct gagactcgat caattacgaa atcaattaat gttgtcgatc
     5281 aagatgtaga aacgttcaat caattaaatg aaaaaggtgt ccatttaatt gcgcaaatgg
     5341 ttccaagtga caaagcagat gactttatgt ctctgttaaa taaataataa tatacgagga
     5401 ggtgaaaaga tggcggggca tttagtttta attagtcatg gacgattttg tgaagagtta
     5461 aagagaagtg ttgatatgat catgggagta caaaaagata tttatactgt agggttatta
     5521 cctgaagagt cagcaaaaga ttttcgagta aatttcgaaa aaacaattaa tggtttgaaa
     5581 aaagttacag ttctggctga tctaatggga ggcactcctt gcaatgttgt ttctcaatta
     5641 attttagaag gaaaagaaat agaactatat gcaggaatga atatgccaat ggttataggc
     5701 tttgttaata atcaattttt aggagaagat agttctttgg taaataaagg aagagaaaat
     5761 attatacatg taaatgaata tttggaagta aatccaatag atttagaaga tgaatgaatg
     5821 tggaggaatt tatgaa
//
LOCUS       DAPBCF010000106         5691 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.110, whole genome shotgun sequence.
ACCESSION   DAPBCF010000106 DAPBCF010000000
VERSION     DAPBCF010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.110"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(490..1299)
                     /locus_tag="RD508_002780"
     CDS             complement(490..1299)
                     /locus_tag="RD508_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7737291.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1299..2045)
                     /locus_tag="RD508_002781"
     CDS             complement(1299..2045)
                     /locus_tag="RD508_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7737292.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2063..2530)
                     /locus_tag="RD508_002782"
     CDS             complement(2063..2530)
                     /locus_tag="RD508_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7737293.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2530..2940)
                     /locus_tag="RD508_002783"
     CDS             complement(2530..2940)
                     /locus_tag="RD508_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDT7737294.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2951..3964)
                     /locus_tag="RD508_002784"
     CDS             complement(2951..3964)
                     /locus_tag="RD508_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7737295.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4181..4915
                     /locus_tag="RD508_002785"
     CDS             4181..4915
                     /locus_tag="RD508_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7737296.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4899..5609
                     /locus_tag="RD508_002786"
     CDS             4899..5609
                     /locus_tag="RD508_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7737297.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQSGSVAKF"
BASE COUNT         1833 a         1195 c          943 g         1720 t
ORIGIN      
        1 taaagcgaca aaaaccacga gcaggtccat tcatcctcaa acctcggtga tcttcgcggt
       61 ttaacaccat cagaagaaat gcacaaaaat aataaggaga gtctgagaca taaataaatt
      121 cccagacttt tagtgagtct aaatccgaat aaacggtggg tcgaaagcaa ctctagctgc
      181 gcgtcgatcg cagcaatctc taggtgctat gttcggataa atggtggtca aaagtcagat
      241 tttcggccat ttcgtaacag ccaaccagac aaaaagcgtc tgttttgtct tctactccaa
      301 ttgctcaaat cttagcgact tttggcttgg tcttactcta aacagtttgt aagcctaaac
      361 tttatttgct gtttgtttct aagatcaaag caaaactact ttttagttgg ttacttttac
      421 aagttctttt tactgttgaa taaatgtaaa tcttaagaac aaatatttac ttctataatt
      481 ccaagtttct taaaaaattc cgccaagtgt acctaaaaag cataaaacaa aaattcctag
      541 aataattgtg atcgttttat gccctttgga gtaaagccag acgcataaaa aggtaattcc
      601 taatggcagc aagcccggaa aaatttgatc aaaaatactt tgtaatgaag tttcagctcc
      661 accaaccgtg aattttagtg acgtatttaa agtaaccatc gtgcctatca tcgcgccaat
      721 taccgttaaa cctaaaatcg aagcaccatg agataatttg tcaatcatat ggttgtcttc
      781 tgtatcatca ataaatttag ttcctaaaac atagccatat tttgtcgcca accatttaaa
      841 aataaaatga atggcagtat acaaagtaaa ataaaggatc atgcctaaaa tattcccttg
      901 ttgagcaaaa gaaataccta tgccagccgc aataacccga aaagttcccc agaaaaatga
      961 atcgccaata cctgataaag gtcccattaa tcctgttttg attttattaa ttgcgtctgt
     1021 atcaaattca ggatttttag cattttcttc ttccatggtg acggacaagc tcataacaaa
     1081 aggcgcaata tgcggtgtaa tgttaaatgt ttccgtatgg cgctgcaacg ctgtataata
     1141 atcatcatcg ttcggatata ttttacgtaa ggaacgttca ataccattca tttgtccata
     1201 tgccatcatt ttatcgaagg accaagagga ttgcataaaa aaggagcgcc aaaatatact
     1261 tcttaattct tttttcccaa taacactttc ttttaccatt ataaatcttc ctcctcttca
     1321 aaagttagct tttgaacagc cagtaacgct aagcaaagtc cgacgacagc cacaccgaca
     1381 acatccattt tcagatacat tacgccgaca aatcctaaga aaagataagg catcatcgct
     1441 ttattcgcca tcattttaat taataacgct agcccaacac aagaaagcac accggccgca
     1501 acatcaaagc tgtccaatac aacctgagga atcaacttga tcatcgcatt gattgtagac
     1561 acaccaaaat aagtagctac aaaaactaaa atggccgatg gaaccccaac gattaaaggt
     1621 tgagccacat aatgatattt ttgtgctttt ttgaaatcat gattgactaa tgcctcatcc
     1681 attttgttgt taaaatacgt aattggcatt gcataggcga agttacgcca catctgaaga
     1741 aagatggaca aaggtaaagt caacgcaacg gcagttccta ctccttgacc cgattgaatc
     1801 gcaattgctg tacctaaaac actggaagca taaacttcag ggggcgtcgc actccctacc
     1861 ataattgagc ccatgaacat ggattccaag gtggcaccaa taataattcc tgactctaaa
     1921 tctcccaaaa tcaaaccgac aaaaggcgct gtaaatagcg gtctacccat catcgatgca
     1981 ccaaatgtgt attcatcaat agacgccaaa aaagctacca gtgcgattaa tattgcttgt
     2041 atcatattct tcccctcctc ttttagtcat gcaaaggatt gatttttttg tccgttggta
     2101 cagcctgaca ttgaactgtt atcccgtttt cagtcatttt tttcaccaag tccagttctt
     2161 gttcattcaa gtaaacggaa ctagtaatca ttttccgatt ctcgtttttc tttaaatttc
     2221 ctaaattcac ttctttaatc tcaggtacgt gctgagtaat ttcgtaggca tcctccaccg
     2281 tcccgacaat taaaaatact tggtatttct tgattttttc tccatttaaa acagagatgg
     2341 cctctgtcat atccttcacc acaaattttg tccctgtagg aacagccatt tttagtgttt
     2401 ttttgcgcag attattggta gcgatttcat tacttgcaac gaaaatacaa tttgcaccta
     2461 agttatttgt ccaggcaaaa gcaacttgcc catgaacaaa acgttcatct actcgtaata
     2521 atttaatcat taaaaatcat cctcttctgt tttctctagc aactcgttca ccaaaactat
     2581 cccttcattc ccgctattca tagctttttg gattagtttt ttcgtgtcct gttcacctga
     2641 taagcaaagc tctaaaagca gcggcagatt tacaccgctg attaaataaa aattgtcttt
     2701 accgatttgt tcggagaaag cgttagacac gcttcctccc agtaaatcta ccgtcacaat
     2761 taattcgtca tcaggcgcta agtcggaaaa tagctgctct atttcctggt taatggagta
     2821 gtcactatct atatacgcag ttattgctaa aagtgatttt tgaggaccaa taataaattc
     2881 taaagtatcc tttaagcctt tagccatcat ggaatgcgtc gcaattacaa ttttcctcat
     2941 agctcttacc ttaatattcc acagtccgat aataacgacg aatatctagt gaatgatccc
     3001 gcaccttttc aaaatgagca ctcactcgtt ctaaggccgt tgccataacc attggcgcta
     3061 catactgacg catagcgctt ggtacacctg ctaattcgaa atccgcagtg tcaaaaaccg
     3121 tcacaacatc gctatattta tttacaaaac gctctacgcg atcgactagc ggacgcgttt
     3181 gatcttcacc ttttaataac acaaaactca tagatttatc agtcatttca atagtcccat
     3241 ggaaaaattc ggctgcatgg atcgacttgg tggcaatcca ttgcatttct tccagtacgc
     3301 acatagcata ttcataggca gccccataag tattcccggc tccaacaaac atatgaaatt
     3361 ccgtattttt atgtttttct gcaaattcaa gtgctttctg atcattttgt tgccgaacac
     3421 ttagtaatac ttccggcatt ttttgtaatg tttgaataaa ttcatcatat tcaggaaact
     3481 caccgttatt tttcatcagg cgtgcaccca aagcaaaaaa ctgtaactga agttcttcta
     3541 ctaatgtatc gttgtcagca tcattttcaa tcgcataatc cacgatttcc ccgagtggtg
     3601 tagcagcatt tcctacaaac gcaatcgtcg ttgcaccttg actattggca tacttaacaa
     3661 catcaacggt ttcttgagtc gtaccggtta atgaagatgt gattaacact gtatctttat
     3721 taatcttttt cggctgtgaa caaaccacct ctgcggctat ttcatgataa taatcaagct
     3781 ctgaatgagt gcttaacaga taagctagcg ggctgattgt ggcatatgtt ccaccagagc
     3841 ctaccaaata aagattttta aatcccttct cactgattgc atctgccacc tgattgattg
     3901 tctcgatatt ttttactgca ccatttaata ctgatagaaa acgttcttcg ctaaaaccta
     3961 acatagttaa aaacctccaa gtcaataatt tgaaaaatat atttgcaaat gccggcacat
     4021 taacaaacca cttaaccttt tttatatacc acctgttaac gtttttaatg taccacttat
     4081 agaaaacgct gtcaatagtt tttaaccact tttattttta tttgtaccaa aatccttttt
     4141 tcatgtataa taaacaaaaa tagactctgg agtgtaacgt atgaatactg aagaactaac
     4201 gaacaaatta atacaagaca ttgaacaaga aaaatataaa tacgcgcaag ctattccttc
     4261 agaacgtgat tttgttcaaa tttatgaaat gaatcgttca gccgtaaaaa aagccattca
     4321 acaattagta aataaagagt acctactaaa aatacatggc aaaggaactt ttgttaaaaa
     4381 aaatatccat gaacatttgc aaatcaaatt tcatggtttg tctgaattgt tggaacggga
     4441 agggattcag cctagcagct taattttagc ttcagaaata aaaccggctg gacacattgt
     4501 cgggaaagct ttacagctgg aaccaactga agaagtattt catttggttc gtttaagaag
     4561 cggcgacggt gagccaattt ctattgaaga cacttatatt ccattaaatc tcatacctga
     4621 tcttcaagct tttgatttcc aaattttttc attttattcc acattggctg cttatcatta
     4681 tcaaattgaa aatatctatc agacaatttc cagctcaaaa gtgagcaata aagaagcccg
     4741 tttgttaaaa accagcttaa atcgtccggt aatcagcctt gctatcactg cggttacgac
     4801 aaatgaacaa gcggttgaat acactgaagt agtggttttg cctgaattcg ccgccatcta
     4861 tactaaaaat gttcatcaag gaaaggagat gaaaatctat gcccaaattg attaatctgt
     4921 tggcttatga cctgattgac aaaattattg cttatattca tgaacatcat ttaacccccg
     4981 gaacaaaact gccttcggaa cgggacctat cagaaatgtt taatgttaat cgaactacct
     5041 taagaggcgc gttacaaaaa ctggtggaca acggcacctt acgggcgcaa accaatagcg
     5101 gctattattt aactgcgcca aaattcgaaa aaaatgccca tcatttcttt acaccgatag
     5161 aagattctct gcttagtaag cagcggctac agctaaaggc aacggctctt tcaccgaaaa
     5221 aagcagcagc tctttgtccg gaactgaatg atttcaaaca gcagcaacca caagcttatt
     5281 tagaatatat tgatgcagaa gcaattagct tgatgttatt aatccctatg gaaacattaa
     5341 agaaaagtaa tttctcggac aatcctttcc aagattttaa aagtttggca tatacgcgtt
     5401 ctcaagaaat ttctttaata actgacaatg acgttgcggc ggacttgctg ggagttgaca
     5461 aagaagaggt tctgttattt gtacgagagg aaataagagc cggtaaggag ttggcggcga
     5521 ttgctttagg ttatactatt agtcgccgct gcaacataca ggttaatgtt gctacgacct
     5581 tgcaatccgg ttctgttgca aagttttaaa tctactatca gataaggtag aataatagaa
     5641 aaagatagca ggaggaatga cgatgagtca ttttaaagga aagcaatttc a
//
LOCUS       DAPBCF010000107         5682 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.111, whole genome shotgun sequence.
ACCESSION   DAPBCF010000107 DAPBCF010000000
VERSION     DAPBCF010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.111"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            133..1287
                     /locus_tag="RD508_002787"
     CDS             133..1287
                     /locus_tag="RD508_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDT7737298.1"
                     /translation="MEYSEERQRLAYVRLYGGILHLRDSVRISEKEKIKITEMYTSIN
                     GELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQ
                     REMLLDALLEISDSDPLLQYYVDSTTHEIILSFLGKVQMEVISALLQEKYHVEIELKE
                     PTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSF
                     QNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKA
                     GTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEY
                     RSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            1385..2758
                     /gene="tet(L)"
                     /locus_tag="RD508_002788"
     CDS             1385..2758
                     /gene="tet(L)"
                     /locus_tag="RD508_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HDT7737299.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            3322..4584
                     /locus_tag="RD508_002789"
     CDS             3322..4584
                     /locus_tag="RD508_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HDT7737300.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            4829..>5682
                     /locus_tag="RD508_002790"
     CDS             4829..>5682
                     /locus_tag="RD508_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HDT7737301.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHK"
BASE COUNT         1955 a          805 c         1167 g         1755 t
ORIGIN      
        1 tccttgtacc ctgtttatca tggaagcgca aaaagcaaca tagggattga gcagcttata
       61 gaagtgataa cgaataaatt ttattcatca acatacagaa agaagtctga actttgcgga
      121 aatgtcttca aaattgaata ttcggaagaa agacaacgtc ttgcatatgt acgcctttat
      181 ggcggaatcc tgcatttgcg ggattcggtt agaatatcgg aaaaggaaaa aataaaaatt
      241 acagaaatgt atacttcaat aaatggtgaa ttatgtaaaa ttgataaggc ttattccggg
      301 gaaattgtta ttttgcaaaa tgagtttttg aagctaaata gtgttcttgg agatacaaag
      361 ctattgccac agagagagag aattgaaaat ccgctccctc tgctgcaaac aactgttgaa
      421 ccgagcaaac ctcaacaaag ggaaatgtta cttgatgcac ttttagaaat ctccgacagt
      481 gacccgcttc tacaatatta tgtggattct acgacacatg aaattatact ttctttctta
      541 gggaaagtac aaatggaagt gattagtgca ctgttgcaag aaaagtatca tgtggagata
      601 gaactaaaag agcctacagt catttatatg gagagaccgt taaaaaatgc agaatatacc
      661 attcacatcg aagtgccgcc aaatcctttc tgggcttcca ttggtttatc tgtatcaccg
      721 cttccgttgg gaagtggaat gcagtatgag agctcggttt ctcttggata cttaaatcaa
      781 tcatttcaaa atgcagttat ggaagggata cgctatggtt gcgaacaagg attatatggt
      841 tggaatgtga cggattgtaa aatctgtttt aagtatggct tatactatag ccctgttagt
      901 accccagcag attttcggat gcttgctcct attgtattgg aacaagtctt aaaaaaagct
      961 ggaacagaat tgttagagcc atatcttagt tttaaaattt atgcgccaca ggaatatctt
     1021 tcacgagcat acaacgatgc tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa
     1081 aataatgagg tcattcttag tggagaaatc cctgctcggt gtattcaaga atatcgtagt
     1141 gatttaactt tctttacaaa tggacgtagt gtttgtttaa cagagttaaa agggtaccat
     1201 gttactaccg gtgaacctgt ttgccagccc cgtcgtccaa atagtcggat agataaagta
     1261 cgatatatgt tcaataaaat aacttagtgt attttatgtt gttatataaa tatggtttct
     1321 tgttaaataa gatgaaatat tttttaataa agatttgaat taaagtgtaa aggaggaatt
     1381 aattatgaag tgtaatgaat gtaacagggt taaatacaac caaattttaa tttggctttg
     1441 cgttttatct ttttttagcg tattaaatga aatggttttg aacgtctcat tacctgatat
     1501 tgcaaatgat tttaataaac cacctgcgag tacaaactgg gtgaacacag cctttatgtt
     1561 aaccttttcc attggaacag ctgtatatgg aaagctatct gatcaattag gcatcaaaag
     1621 gttactccta tttggaatta taataaattg tttcgggtcg gtaattgggt ttgttggcca
     1681 ttctttcttt tccttactta ttatggctcg ttttattcaa ggggctggtg cagctgcatt
     1741 tccagcactc gtaatggttg tagttgcgcg ctatattcca aaggaaaata ggggtaaagc
     1801 atttggtctt attggatcga tagtagccat gggagaagga gtcggtccag cgattggtgg
     1861 aatgatagcc cattatattc attggtccta tcttctactc attcctatga taacaattat
     1921 cactgttccg tttcttatga aattattaaa gaaagaagta aggataaaag gtcattttga
     1981 tatcaaagga attatactaa tgtctgtagg cattgtattt tttatgttgt ttacaacatc
     2041 atatagcatt tcttttctta tcgttagcgt gctgtcattc ctgatatttg taaaacatat
     2101 caggaaagta acagatcctt ttgttgatcc cggattaggg aaaaatatac cttttatgat
     2161 tggagttctt tgtgggggaa ttatatttgg aacagtagca gggtttgtct ctatggttcc
     2221 ttatatgatg aaagatgttc accagctaag tactgccgaa atcggaagtg taattatttt
     2281 ccctggaaca atgagtgtca ttattttcgg ctacattggt gggatacttg ttgatagaag
     2341 aggtccttta tacgtgttaa acatcggagt tacatttctt tctgttagct ttttaactgc
     2401 ttcctttctt ttagaaacaa catcatggtt catgacaatt ataatcgtat ttgttttagg
     2461 tgggctttcg ttcaccaaaa cagttatatc aacaattgtt tcaagtagct tgaaacagca
     2521 ggaagctggt gctggaatga gtttgcttaa ctttaccagc tttttatcag agggaacagg
     2581 tattgcaatt gtaggtggtt tattatccat acccttactt gatcaaaggt tgttacctat
     2641 ggaagttgat cagtcaactt atctgtatag taatttgtta ttactttttt caggaatcat
     2701 tgtcattagt tggctggtta ccttgaatgt atataaacat tctcaaaggg atttctaaat
     2761 cgttaaggga tcaactttgg gagagagttc aaaattgatc ctttttttat aacaggaatt
     2821 caaatctttt tgttccatta aagggcgcga ttgctgaata aaagatacga gagacctctc
     2881 ttgtatcttt tttattttga gtggttttgt ccgttacact agaaaaccga aagacaataa
     2941 aaattttatt cttgctgagt ctggctttcg gtaagctaga caaaacggac aaaataaaaa
     3001 ttggcaaggg tttaaaggtg gagatttttt gagtgatctt ctcaaaaaat actacctgtc
     3061 ccttgctgat ttttaaacga gcacgagagc aaaacccccc tttgctgagg tggcagaggg
     3121 caggtttttt tgtttctttt ttctcgtaaa aaaaagaaag gtcttaaagg ttttatggtt
     3181 ttggtcggca ctgccgacag cctcgcagag cacacacttt atgaatataa agtatagtgt
     3241 gttatacttt acttggaagt ggttgccgga aagagcgaaa atgcctcaca tttgtgccac
     3301 ctaaaaagga gcgatttaca tatgagttat gcagtttgta gaatgcaaaa agtgaaatca
     3361 gctggactaa aaggcatgca atttcataat caaagagagc gaaaaagtag aacgaatgat
     3421 gatattgacc atgagcgaac acgtgaaaat tatgatttga aaaatgataa aaatattgat
     3481 tacaacgaac gtgtcaaaga aattattgaa tcacaaaaaa caggtacaag aaaaacgagg
     3541 aaagatgctg ttcttgtaaa tgagttgcta gtaacatctg accgagattt ttttgagcaa
     3601 ctggatccag gagaacaaaa acgatttttt gaggaaagtt ataaattatt ttccgaacga
     3661 tatggcaagc aaaatattgc ttatgcaaca gttcataatg atgagcaaac ccctcacatg
     3721 catttaggtg ttgtgcctat gcgtgatgga aaactgcaag gaaaaaatgt gtttaatcgt
     3781 caagaactgt tatggctaca agataaattc cccgagcata tgaaaaaaca gggttttgag
     3841 ttgaagcgtg gtgaacgtgg ctctgaccgt aaacatattg agacagctaa atttaaaaaa
     3901 caaactttgg aaaaagagat tgattttcta gaaaaaaatt tagcagttaa aaaagatgaa
     3961 tggactgctt atagcgataa agttaaatca gatttagaag taccagcgaa acgacacatg
     4021 aaaagtgttg aagtgccaac gggtgaaaag tccatgtttg gtttgggaaa agaaataatg
     4081 aaaacagaaa agaaaccaac caaaaatgtt gttatatcgg agcgtgatta taaaaactta
     4141 gtgactgctg cgagagataa cgataggtta aaacagcatg ttagaaatct catgagtact
     4201 gatatggcga gagaatataa aaaattaagt aaagaacatg ggcaagttaa agaaaaatat
     4261 agtggtcttg tagagcgatt taatgaaaat gtaaatgatt ataatgagtt gcttgaagaa
     4321 aacaagtctt taaagtctaa aataagcgat ttaaagcgtg atgtgagttt aatctatgaa
     4381 agcactaagg aattccttaa ggaacgtaca gacggcttaa aagcctttaa aaacgttttt
     4441 aaggggtttg tagacaaggt aaaggataaa acagcacaat tccaagaaaa acacgattta
     4501 gaacctaaaa agaacgaatt tgaactaact cataaccgag aggtaaaaaa agaacgaagt
     4561 cgagatcagg gaatgagttt ataaaataaa aaaagcacct gaaaaggtgt ctttttttga
     4621 tggttttgaa cttgttcttt cttatcttga tatatataga aataacgtca tttttatttt
     4681 agttgctgaa aggtgcgttg aagtgttggt atgtatgtgt tttaaagtat tgaaaaccct
     4741 taaaattggt tgcacagaaa aaccccatct gttaaagtta taagtgacca aacaaataac
     4801 taaatagatg ggggtttctt ttaatattat gtgtcctaat agtagcattt attcagatga
     4861 aaaatcaagg gttttagtgg acaagacaaa aagtggaaaa gtgagaccat ggagagaaaa
     4921 gaaaatcgct aatgttgatt actttgaact tctgcatatt cttgaattta aaaaggctga
     4981 aagagtaaaa gattgtgctg aaatattaga gtataaacaa aatcgtgaaa caggcgaaag
     5041 aaagttgtat cgagtgtggt tttgtaaatc caggctttgt ccaatgtgca actggaggag
     5101 agcaatgaaa catggcattc agtcacaaaa ggttgttgct gaagttatta aacaaaagcc
     5161 aacagttcgt tggttgtttc tcacattaac agttaaaaat gtttatgatg gcgaagaatt
     5221 aaataagagt ttgtcagata tggctcaaag atttcgccga atgatgcaat ataaaaaaat
     5281 taataaaaat cttgttggtt ttatgcgtgc aacggaagtg acaataaata ataaagataa
     5341 ttcttataat cagcacatgc atgtattggt atgtgtggaa ccaacttatt ttaagaatac
     5401 agaaaactac gtgaatcaaa aacaatggat tcaattttgg aaaaaggcaa tgaaattaga
     5461 ctatgatcca aatgtaaaag ttcaaatgat tcgaccgaaa aataaatata aatcggatat
     5521 acaatcggca attgacgaaa ctgcaaaata tcctgtaaag gatacggatt ttatgaccga
     5581 tgatgaagaa aagaatttga aacgtttgtc tgatttggag gaaggtttac accgtaaaag
     5641 gttaatctcc tatggtggtt tgttaaaaga aatacataaa aa
//
LOCUS       DAPBCF010000108         5609 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.112, whole genome shotgun sequence.
ACCESSION   DAPBCF010000108 DAPBCF010000000
VERSION     DAPBCF010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.112"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..117
                     /locus_tag="RD508_002791"
     CDS             <1..117
                     /locus_tag="RD508_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7737302.1"
                     /translation="TIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
     gene            142..594
                     /locus_tag="RD508_002792"
     CDS             142..594
                     /locus_tag="RD508_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737303.1"
                     /translation="MLYLKLCNRTVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            608..1297
                     /locus_tag="RD508_002793"
     CDS             608..1297
                     /locus_tag="RD508_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737304.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1422..3773
                     /locus_tag="RD508_002794"
     CDS             1422..3773
                     /locus_tag="RD508_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HDT7737305.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3853..4248
                     /locus_tag="RD508_002795"
     CDS             3853..4248
                     /locus_tag="RD508_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737306.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4573..5190
                     /locus_tag="RD508_002796"
     CDS             4573..5190
                     /locus_tag="RD508_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7737307.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5231..5530
                     /locus_tag="RD508_002797"
     CDS             5231..5530
                     /locus_tag="RD508_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HDT7737308.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
BASE COUNT         1959 a          752 c         1144 g         1754 t
ORIGIN      
        1 acgattaaag gcatggaagc catccgagga ttatataaga aaacccgaaa agaaggcact
       61 ctcttcgggt tttcggtctg tactgaaatc aaggtattat tgggaatccc agcttaaatc
      121 atagataccg taagggattt tattctttat ttaaaacttt gcaacagaac cgtatttaca
      181 atattaattg ggggctattt tcttttgaat ttagattctg ttaattcaaa cgctcaaata
      241 aaagatcaaa gagtagctga acataataat aaaaaaatga gtttgaccaa aaatatctat
      301 tctatgtcag atgaagaatt gtataaagaa tttggtgatt tatccgggga acagttagaa
      361 gaaagtattc caggaattag tgactcagat aaaattgttg tcttgtctgc tggtgggcaa
      421 ttaatgggag atggcaaatc cgaattagtt agttataaac aaaatcacag acagtttatt
      481 gatgttaata ctgattccaa cgctatttcg attaaggatc taaaagagct tttaaatagt
      541 aaaagaaatg aattaaagca gataaaagaa actaattcag tggaattaga gtaaaggaag
      601 attcattatg aaaaagattt ttggtgtttc tgttgggcta cttatgatgt taacatttgg
      661 aaatgcagta tatgctgctg agaaagaagt tatttcagat ccagagcagt acgcctcacg
      721 atactttgct gattttgaag aagaagataa agtacttgca ttgccagaag gtggtttttt
      781 aaaaggggaa gctaaaattg tatctatgga taatccagat ataattcaag gttcatataa
      841 ttcagaaact gatcctgctt cagtttcagt gacagaagca aaaaaaattg ttgctgaaaa
      901 attcaaaaat gatattgaaa ctactccaat tatgcctcga ggagcatttc cacccgatgt
      961 tggtactagc ggacaccttc ttgtactagc aggaggagga agctataaat cacagccatt
     1021 tagtggtgcg ggatggcgtt ttggaggtat gggtgtaaaa ccagctgatg gtacaggcaa
     1081 ctttttacgt tggaaatcct acattgacga tggaagagta ggaaatgtaa atcaagccaa
     1141 cgcaactaaa tctggttcta ttcaaggaat ggcattgtat gctcgtgaag gattcaaata
     1201 ctttgcacca aacgggcctg gttggacaat gaatataggt atttattaca cttataatcc
     1261 tgttgcaggt acgtattatg ttgttcaaaa tatttaataa aacagcacaa agagatttct
     1321 ttgtgctgtt ttattatttt tagttgttga caaacactaa aatataaaat ataatcaaca
     1381 cataaacgaa cgtatgttcg gcaagaaagc aggggatttt tatggatgag atggttttaa
     1441 gtactcagaa atggctaaac aagaaataca gtaatgttac agggtttgat aaggttccag
     1501 aaaatgggcg aacagggtgg cctacaatct atggacttat tgaaggacta caagtagaac
     1561 ttggtattac taatctagta gctaattttg gacctaccac tgaaaaaatg tacgataatc
     1621 aggttactcc taaatggggc aaaaatctac ctaaaaatat tgtatttctt attcaaggtg
     1681 ccttttggtg taaggggatt aatccaggtg gcttcgatgg ggtatatact ccatatttag
     1741 atactgctgt aaaagagttg cagactgatg cagggtttaa tggaagcgct gtaactggag
     1801 ttttggatgc gaaatgggcc aaagcgttat ttgatatgag tgcttttgtt cttgttcccg
     1861 gcggagatag taaaattaga aaaatgcagc aatggttaaa tgtaaattat ttagaataca
     1921 cgggaataat gccttgtgat ggtatttatc aaagaaattc aaatcaagca ttaatttttg
     1981 cattacaagc tgaactagga tattctccca gtgaagcaac agggtcttat ggtaatggga
     2041 caactagtaa aacttatcct gtgtctgaag gtaactcggg aaactatgta agaataattc
     2101 aatatggatt atatgttaat ggttattttg aagacggtac attcgatggt attttcacta
     2161 aatatatggg tttagaagta ctggcattcc gaaaatttat ggtattgcct gaatatactg
     2221 aaatagcaga tgttgttgta ataaaaggac tattgtctag cgctggagat attagaagat
     2281 ctgcagatgg cgcagatact tctacgcaat taactagatc tcaaatccaa acattggttg
     2341 ataatgatat aaaaatagtt ggtagatatc ttactggtac tgttggaatt ggaaaagatg
     2401 aacgaaataa gtatctaact acagaggaat tgaataatat tttttctaaa aatttatctg
     2461 tgtttcctat ctatcaagat ggaggtgcag cattagctta ttttacttat gatcgtggct
     2521 tatcagatgg taagaaggct atagatgcag caaaaaatct aaatatacca ttaacaacag
     2581 ttatttattt tgctgttgat ctagacatgt taggggaaga aattcttgca tatgctggag
     2641 aatattttaa gggggtatct gctgtaatgt catatagcgg gtatcaaacg ggtgtttacg
     2701 gaacaagaaa tgtttgttct caaataatca ataacgggta tgcttcgttt gcatttgttt
     2761 cagatatgtc gactggttat agtgggaatt taggttttcc tatgcctaga caatggtctt
     2821 ttgatcaatt tgttgaattt accataggaa gtggcaacgg agctgttggt atcgatttaa
     2881 tcgctacatc gggtagagat agcggattta atgagttatc aaatgatact aataatgata
     2941 attacattgc caaatacaat cagaaggtta taaatcagat ggtacgtgcg tatcaatatc
     3001 tatcacaagc tggtcttgat aatccttgga accctcattt gacattttat agatatgtaa
     3061 attattctgg tttgtcatgg gacatcattt cttctcctgt aacagagcat gatagaaaaa
     3121 tttatgatga atataggaat aaattaacta atagcgaggg cctgtataat tattttatag
     3181 atcctaatac tggttcaata ataggtttgc ctcacttaat tgtgacgtta caatcacaga
     3241 tgtttctagc cgacacaatc aatgatagtg tttctgactt tgcaggttgg ttaggagatt
     3301 taatgacttg ctggggtgaa gttaagaaat taggaataca aatggagcaa ggtgtatttg
     3361 cattagtagg tacggctgca ggtggaacat ttagtctaga agatttatac caagatgttg
     3421 acgcggtaaa tgtttatacc ttagcaaaaa gaaattctga ttcaacagct ttatcggctt
     3481 taaaaacgta ctattgtgat aagggtgcta ttgatagatt taatcaattt gttaagaaca
     3541 gatttggttc ttcagataaa atcgcttcag taacaaatag tttattagaa aatgacgaaa
     3601 cagttgatat cttaggtgta gggataattt catttttcat tgataaaata gttaataatt
     3661 cacttgggac agattttact tatcttgatt ttattggaga tgaggggaaa gttgcaaatg
     3721 gattttctga aaaaattatt caatttcaag aaaatagaag taaacttaat taagaatcgt
     3781 ttactattta aacagtgtcc ttttcctttt taaatatata cgataaaata agtatatgaa
     3841 ttgtaaaagg acatgatgat tatggaagaa atagaatgga ataatctgac tcaaaataat
     3901 aaaaataatt ctggatgtgg aattatcttt atgtttgtta tagttttggg aatagtagta
     3961 cttttaataa ctgtcaagat agtagattac tttgcgaata ctcctgaaga acaaatacag
     4021 agaaaacttc ctgagtttga aagagtacca ccttatgatc caagagataa ttcatttcaa
     4081 gtaaaaaaat taaaagagtc tccaaatgaa atgtggtttg aagttacagt tgaatcaagc
     4141 gacttcaaag aaaaaaagaa agaatacaat tatattgtaa aggcaaaagt atcaaaaaga
     4201 tttattttta accctaaatt agaaatatat agtgttgtaa tagaataata gtgttaaaaa
     4261 aattgtaaaa gttaaagaag tcaaattctg atgtgaaaaa taaaatatac catggaagac
     4321 ataaaagaaa aactggataa ctagtttatt taatggcaga ccgttaaggc ctgccatttt
     4381 tatgtatttt agcggaataa atataatcat gcgggagtgt aaacttactg tttcaaaaag
     4441 tatacttttt gacatgcctt gattttcttt gtttatgtat ggcataataa ccacataata
     4501 caatttgaaa cgtttctgat ttaatctgat tgttttgaaa caattttagt gaaaaaaggg
     4561 tagataaaaa cgatgagaaa atttttttat atccgggtca gtagttatga tcaatcgatc
     4621 gaacgacaac tgatttccgc gaaggaatta ggaatccctg aagaatatat atttgtagaa
     4681 aaagccagcg gcaaagattt taaacgccct gaatatcaat taatgaaacg gatgtttcga
     4741 aaaggagatt tactctatct acaatcatta gatagactag gcagaaataa acaaatgatt
     4801 ttagaagaat ggcgagaatt aactaaggaa aagcagattg atatttctgt gttagacatg
     4861 cctctgttag atactgctag ttacaagcaa ctagatgggt tagagacgct tatctctgac
     4921 ttaattctgc aattactcag ctatatggcc gaagacgagc ggaaacgaat taatagccgg
     4981 caaagagaag gcgtagaagc tgcgaaacaa aagggtgtaa aattcggcag aaagaaaatt
     5041 gctttacctc ctgaatttcc tgcgatctat tctgactgga aagcaggaaa gataactgca
     5101 gtctatgcta tggatcaatt gggcatgaaa cgaaatacct tttatcgacg ggtgaaagaa
     5161 tatgaacata ccttgcacca cttttcttga tagatataac agctattaga cgggaaggga
     5221 gagtttgaaa atggacttaa cgaatcaaag ggtcgttttt actggaacgc tgcagcaaat
     5281 gacacgaacc caagccatcg gtttggttca ctctttaaac ggccattgtc aatcaagtgt
     5341 tacttcaaaa acaaatttcc tggtttgtgg tcagtattct aagtcgttgt ttgatgattc
     5401 tctctataca aaaaaggaac aaaccgcgcg ggacttgatt gcgttaggtc atgagattac
     5461 cattttatca gaagtcgaat tttatgcgtt aattagtcaa cagttgaaag aatggcaacg
     5521 gtatttataa tcgttagtaa aatttacaag gaggaaaatt tttatgaagc gaaaatctta
     5581 tgatcgttgg ggcattgaaa taactagtt
//
LOCUS       DAPBCF010000109         5504 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.113, whole genome shotgun sequence.
ACCESSION   DAPBCF010000109 DAPBCF010000000
VERSION     DAPBCF010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.113"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..546)
                     /locus_tag="RD508_002798"
     CDS             complement(<1..546)
                     /locus_tag="RD508_002798"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737309.1"
                     /translation="MNIITRDELIYAYKDEVNLLEVSQYRSSNVITLNIDTVSEFIKL
                     AKELKINHVYYNYLYYSIDNYLIPLDTYDEFSDEINIEVKKHNEVVDSLDFSKPKQLT
                     LLIVLNGTIMEITLNHFWIKESGIPDNETKHSEIQDKFFKDFKLQQEEISRNEHDDKN
                     RLKEYILSDNEFSYMKNQRLRQ"
     gene            complement(651..1214)
                     /locus_tag="RD508_002799"
     CDS             complement(651..1214)
                     /locus_tag="RD508_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7737310.1"
                     /translation="MSGYIYGYARVSTRSQELNRQIDLLNEQNCNEILTEKMTGTKAD
                     RPQLNRLKDKVRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHEVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQRDIERAVKLYDSQ
                     IYSIKEITEMTGISKATLYRYLKTNNF"
     gene            1590..1820
                     /locus_tag="RD508_002800"
     CDS             1590..1820
                     /locus_tag="RD508_002800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737311.1"
                     /translation="MLKNLFFKNKKQLTILEKIFYFFVGNKNRMQNKSYYVRERAGAK
                     WRYRKFKDPWIAKNRNTLFKRVFGFFEDIFRG"
     gene            complement(1855..2004)
                     /locus_tag="RD508_002801"
     CDS             complement(1855..2004)
                     /locus_tag="RD508_002801"
                     /inference="COORDINATES: protein motif:HMM:NF025625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4357 domain-containing protein"
                     /protein_id="HDT7737312.1"
                     /translation="MIEKNGVLRTILDISYNSPSRVAELISGNSTNGWSFVEGLSELR
                     TMDQE"
     gene            2079..2342
                     /locus_tag="RD508_002802"
     CDS             2079..2342
                     /locus_tag="RD508_002802"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737313.1"
                     /translation="MILQVYNEQQGLTGGSSESSSSPESSEPESAAPSTPAGGDVSSV
                     DTNGNGNVTIKEAKAAGYSMPITSDHWLYQYMNDRDNDGMVGE"
     gene            complement(2442..2957)
                     /locus_tag="RD508_002803"
     CDS             complement(2442..2957)
                     /locus_tag="RD508_002803"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737314.1"
                     /translation="MIHVEQGLTDIQVVPTALVDSEWKFIKDLTIYLEENERIFEGKE
                     LYLIRNFSRKGIGFFEESGFYPDFIMWYFNGSQEYIIFIEPHGMLRENLDGNKVQLYK
                     EIKKVENEISLSEGTRPVLESFILSPTPFATLNNPINNPSNYSKGDLNRQHVIFMEDE
                     NYIEQLFESLI"
     gene            complement(3022..3537)
                     /locus_tag="RD508_002804"
     CDS             complement(3022..3537)
                     /locus_tag="RD508_002804"
                     /EC_number="3.2.2.15"
                     /inference="COORDINATES: protein motif:HMM:TIGR04274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-deoxyinosine glycosylase"
                     /protein_id="HDT7737315.1"
                     /translation="MVPLTSEKIFGLAPIIDDQAKILILGSMPGKESLKKEQYYANKR
                     NQMWKIMENTLKLQLPEEYPKRINVLRKHHIALWDVIHSCKRVGSLDSAITEDVPNDF
                     GSFFKEYSSLKIVGFNGNKAYQTFKSKIGFQDFPEIQFIKLPSTSPIPGKNVKSFEEK
                     VVEWSKVVNSL"
     gene            complement(3846..4208)
                     /locus_tag="RD508_002805"
     CDS             complement(3846..4208)
                     /locus_tag="RD508_002805"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737316.1"
                     /translation="MADNLLNKNKGKRNLLERKEEVKPQQSFNRSSLFTVNESQQTNG
                     DQKKDVPRKKERGTTTTIRCATDTSHRLNAIVTSFNLDSVNELIEILLDNYEASLTTD
                     ERREIKTLLEVYQRKSKK"
     gene            complement(4250..5086)
                     /locus_tag="RD508_002806"
     CDS             complement(4250..5086)
                     /locus_tag="RD508_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7737317.1"
                     /translation="MAKVITFGNFKGGTGKTTNSAMMAYTLSKLGYKTLLADLDPQAN
                     ATSLYLHTKQRITNNIVTFDKTLMSAIADEDLSDIIIEIKENLFLLPSFADFTSYPLF
                     LEKKFPDSQFNRVTFLNELMTKIKDDYDFILVDVPPTLSTYTDSALLASDYTIIVLQT
                     QERSLVGAEAYVGYLQELIDNYNADFDILGVLPVLLKNNSKVDEATLNTAKEKFGEEN
                     LFENVVKNMERLKRYDIIGIVDPDLDTKYDIHDKRVMGLYKRVTEEMLKRLEEIESRN
                     KQ"
BASE COUNT         1727 a          979 c          844 g         1954 t
ORIGIN      
        1 ttgtctcagg cgttgatttt tcatgtaaga gaactcattg tcgctcaata tatattcttt
       61 taatctattt ttatcgtcgt gttcatttct agatatttct tcctgttgaa gtttaaaatc
      121 cttgaaaaat ttgtcttgta tctcagaatg cttagtttca ttatctggta ttccgctttc
      181 ctttatccaa aaatgattta aagtaatttc cattatagta ccattcagta caattagtaa
      241 ggttagttgt tttggtttag aaaaatcaag actatctacc acttcattat gctttttaac
      301 ctctatattg atttcatcag aaaattcatc atatgtatct aagggtatga ggtaattatc
      361 aatagaatag tatagataat tataatatac atgattaatc tttaattctt ttgctaactt
      421 tatgaactcc gataccgtat caatatttaa agtaattaca tttgaggatc gatattgact
      481 cacttccaat aaattgacct catctttata tgcataaatt aattcatctc tagttataat
      541 attcattaac tccacttcct acccgattat tatataatcc aaaaatatca cttcaatcaa
      601 ttattaattt ttcagaatta aagatgaata atttcatttc atgataagat ttaaaaatta
      661 tttgttttta aatagcgata gagtgtagct ttactgatgc cagtcatttc tgtaatttct
      721 tttatgctgt atatttgact gtcatacagt ttcaccgctc tctcaatatc tcgttgatta
      781 acgcgtgggc gtcctccttt tcggcctcta gcacgcgcac tttttaaccc ttctttggta
      841 cgctccacaa tcaaatcacg ttcaaactga ctaaacgctt ggaagacggt catcattaag
      901 cgtccgtgag gagtgctagt atcgaagttt tctttcaaac tcaccagctt cacttcatgt
      961 tcttcaaagt aggtaacgag atcaattaaa tctttggtac tccgacctag acgagagaaa
     1021 ctttccacga taaccgtgtc tccaggacgc accttatctt ttagtcgatt caactgagga
     1081 cgatcggctt tggttccggt cattttttcc gttaggatct cattgcaatt ttgttcattg
     1141 agtaggtcta tttgtcgatt caactcttgc gagcgtgtac tcactctggc atagccatat
     1201 atatatccac tcataaaaaa tcatcctttg tttttgatat tattgtatca taaacgggag
     1261 ttaaaggtgc atacataaag agagaagttt tgagactaaa aaggactact ttttaggtga
     1321 aaaatccgtc ctttaaaatc gtctcataat cgattgtttt tgagacttca ggtttaattt
     1381 taactgactt aattttttga gttattatct aaaagcttta agtttaagga gttgattatt
     1441 ttctggaaac aataaaccaa aatttgttta acctgttgtg ccatataatt tttacttagg
     1501 cacactttaa cgtattttta gtttaggggt atgctaatat agtagttaga tacttacaca
     1561 gtattaaggc tgagccaagg gggaaaggaa tgcttaaaaa cttatttttt aagaataaga
     1621 aacagctaac aattttagaa aaaatattct atttttttgt aggaaataaa aaccgcatgc
     1681 aaaataagtc ctattatgtt cgagaacgtg caggggcaaa gtggcgatat cgaaaattta
     1741 aagatccatg gatagcaaaa aatagaaaca ccctattcaa aagagtcttt ggtttttttg
     1801 aggatatatt tagaggataa atttccaaat aaaaaagagg cccatgcctc ttttttattc
     1861 ctgatccata gtccgcaatt cacttaaacc ttcaacaaat gaccatccat ttgttgagtt
     1921 tcctgatatt aattcagcaa ctctcgaagg actattatag gaaatatcaa gtattgttct
     1981 caaaactcca tttttttcga tcacttttcc atcttcaatg taactgtcaa tcacatcgtt
     2041 atagcgaata aagaaattac cagtcttcca ttgcgcactt gattctacag gtctacaatg
     2101 aacagcaagg tttaacagga ggaagtagtg aatcttcatc ttctcctgaa tcctcagagc
     2161 cagaatctgc cgcaccaagt actcctgctg gaggagatgt ttcctctgta gataccaatg
     2221 gaaatgggaa tgtaaccatt aaagaagcaa aagcagctgg ctattctatg cctattacta
     2281 gtgatcattg gttatatcaa tatatgaatg atagagataa tgacggtatg gttggagaat
     2341 aaaccaaaat aatgaaaaat gaaagaccag attaatgaac tgccccctgt caagtagaca
     2401 gggggcagtt cattcggaaa tttagtctct tttatctgtt tttatattag tgattcaaat
     2461 aactgctcaa tataattttc gtcttccata aatatgacat gttgtctgtt taagtcacct
     2521 ttagaataat tagatggatt attaattggg ttatttaatg tagcaaatgg tgtgggagat
     2581 agaataaagg actctagaac tggacgggta ccttctgaca atgaaatttc attttctacc
     2641 tttttaattt ctttgtataa ctggacctta ttaccatcta aattctctcg caacataccg
     2701 tgaggctcaa taaatattat atattcctga ctgccattga aataccacat gataaaatcg
     2761 ggataaaacc cagattcttc aaaaaatcca attccctttc ttgagaagtt acgaattaag
     2821 taaagttctt taccctcaaa aattcgttca ttttcctcta agtagattgt caagtcttta
     2881 ataaatttcc attcactatc aactaacgcg gtagggacta cttgaatatc ggttagtcct
     2941 tgttctacat gtatcaacgg gttatataaa gatttatgtt tcttttagta ggctctgatt
     3001 ttcaaatcaa tacctaaatg tttataagct atttactacc ttgctccact ctacaacttt
     3061 ttcttcaaac gattttacgt ttttccctgg aattgggcta gtagaaggta acttaataaa
     3121 ctgaatctct ggaaaatcct ggaaaccgat ttttgattta aatgtttgat atgctttgtt
     3181 cccattgaac ccaacaattt ttaaggatga gtattcctta aaaaaagacc caaagtcatt
     3241 tggcacatct tctgtgatgg cagaatctaa actccctact ctcttacaac tatgaatcac
     3301 gtcccataaa gcaatgtggt gttttcttag aacattaatt cgttttggat attcttcagg
     3361 gagttgtaat ttgagggtgt tctccataat tttccacatt tgattccttt tgttagcata
     3421 atattgctct tttttgagag attcttttcc aggcatggat cctaaaatca aaattttagc
     3481 ttgatcgtcg ataataggag ctaaaccaaa tattttttct gaggttaatg gaaccatatt
     3541 tttatcccct ttgtagttca gtcacataag agttaatttt ttaaaacgtt atggtatcta
     3601 atccttgtag tatactagaa tgtttttttt agcttttttt ggtgtctatt gacgacttta
     3661 tcttcgtata tttgaactaa atcctcaaaa cgtttggtgt cactattgtt taaattttca
     3721 acgtataagt ttacaaaagt ccttcccatt tttttgacta catcattgta attgccatta
     3781 tatagcgaaa tttacacgat taaagagaca cgtctacatg tagacgtgtc tacaaatcta
     3841 caaatctact ttttagattt tcgctggtaa acctctagta aagtctttat ttctcttcgt
     3901 tcatccgtcg ttaaagaagc ctcataatta tctaggagga tttctatcag ttcattaaca
     3961 ctatctaaat tgaaagaagt aacgattgcg ttcagacgat gtgaagtatc cgttgcacaa
     4021 cgaatagtag ttgtcgtgcc cctttctttt tttcgaggga cgtctttttt ttggtctcca
     4081 ttagtttgct gagattcgtt tactgtaaat aaactggatc gattaaaaga ttgttggggt
     4141 ttcacttctt cttttcgctc aagaagattc cgtttccctt tatttttatt taataaatta
     4201 tctgccatac tatcaccctc ttctttcttg tatatggtat gaataatgtc tattgtttgt
     4261 ttcgagattc tatctcttct aatcgtttca acatctcttc agtgacacgc ttataaagcc
     4321 ccattactct cttatcgtga atatcatatt tagtgtctaa atcaggatca actatcccaa
     4381 taatgtcata tcgttttaat cgttccatat ttttaactac attttcgaag agattttctt
     4441 caccaaattt ttctttcgca gtattgagcg tagcttcgtc gacctttgaa ttgtttttta
     4501 gtaatacggg tagtacacct aaaatatcaa aatccgcatt atagttatca atgagttctt
     4561 gcaagtaccc tacataagct tcggccccta ccaaagaacg ttcttgcgtc tgtaggacaa
     4621 taatggtgta gtcggaagct aacaaagccg agtccgtata agtacttaaa gtaggtggaa
     4681 catcgaccaa aataaaatcg tagtcatcct tgatcttagt cattaattca tttaaaaaag
     4741 tcaccctatt aaattgactg tctggaaatt tcttttctaa aaataaggga taagaggtaa
     4801 aatctgcaaa gctaggcaat aaaaaaagat tttctttgat ttcaataata atgtccgata
     4861 aatcttcatc tgctatggca gacattagcg tcttgtcaaa agtaacaata ttattcgtaa
     4921 ttcgctgttt cgtatgtaaa tacaaagatg ttgcattcgc ttgaggatct aaatccgcta
     4981 ataatgtctt atagcccagt ttagataatg tgtaagccat catggcacta ttagttgttt
     5041 tacctgttcc acccttaaaa tttccgaatg ttataacttt agccattgta accctctttt
     5101 cttagttgtc tacaaatcta catttgatat tataacgtaa atataccatg ctaaatcaat
     5161 atgtcaaacg ttatcaagaa aaaccgtcta caaatataca tgtagacgta tctacaaatc
     5221 tacacgtcta catgtagacg catatacatt aaaaatcttg ataacaaaag gatatcaagc
     5281 atcatgtata tgcatctaca aatctacaaa tctacatgta gacgtgtata caaatctaca
     5341 aatctacatg tagacgcatc tacagaaaaa cgagattttg cctacaaatt aaggttttac
     5401 aaaaaaaaaa tagtgtagta catttgattt aattcaaagc aaaactaaaa ttgaatacaa
     5461 aaaaagcccc gtagacgcca atctacgaga cacgcaaaac ttat
//
LOCUS       DAPBCF010000110         5212 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.114, whole genome shotgun sequence.
ACCESSION   DAPBCF010000110 DAPBCF010000000
VERSION     DAPBCF010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.114"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            604..954
                     /locus_tag="RD508_002807"
                     /pseudo
     CDS             604..954
                     /locus_tag="RD508_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
     gene            948..1370
                     /locus_tag="RD508_002808"
     CDS             948..1370
                     /locus_tag="RD508_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737318.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2540..3508
                     /locus_tag="RD508_002809"
     CDS             2540..3508
                     /locus_tag="RD508_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDT7737319.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            3525..4049
                     /locus_tag="RD508_002810"
     CDS             3525..4049
                     /locus_tag="RD508_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HDT7737320.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTETHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDHQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKTEKKWWQFWQ"
     gene            4425..4706
                     /locus_tag="RD508_002811"
     CDS             4425..4706
                     /locus_tag="RD508_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737321.1"
                     /translation="MDILVRNINPKIIARIDKRCQELTTKTGKKWSRNKYLKVLIESD
                     FDRQLMNYKKDQFDLLLEKFIAIQTENTNILNDYVHTNNQLIETLIGGI"
     gene            4708..5124
                     /locus_tag="RD508_002812"
     CDS             4708..5124
                     /locus_tag="RD508_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737322.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
BASE COUNT         1967 a          893 c          868 g         1484 t
ORIGIN      
        1 aaaaaaaaga aaaatccgct tatgcaactt cttctttttg tattttgggg cgctacccca
       61 atccccaagt atcggttatt taatagcgcg gaaatccaaa gaataggacg taccctgaaa
      121 caaaaaaaga ctgctctcac gagcagccca aaatgagatt atcctattca tcaacataaa
      181 aatattacaa agtgaagaac tagagaaaga caaaaaaagc atatcaaatc ctctcaaaaa
      241 taacaagtct taaaaaaatg acagataaaa atgcacaaag aattagatat agataaccgc
      301 gaaaaatcaa gctttagaaa gttgctttta gctagaccaa ttaaaaatca caaagtgagc
      361 gtctctatcc attggtagag gggctacttg gcatagtgta cattatgtta actagctcga
      421 taaataacga ttatgttccc aaaacaatat tttatgaact ataacaaaaa tttgttatcg
      481 catattgtat attttaatta tataattata ggtgtatacc acttaaattt aacacaaagg
      541 cgtggttatt ttgaaaccca aaaagaaaat ttatctaggt ctcctctttt ccttgatgat
      601 tggaatagtc aaattgaatc aaaaagtctt aatcaagatc aaataataaa atatgcaaat
      661 tactgtggtg tttatcctaa aaaagtagca cgaatactaa acctttcaga ggtccaaaca
      721 caactaagaa aaggaaatgc catttatatg ggaactgctg gttatggaaa ttatagtaac
      781 agccgtcatg cacttgcatt atttgggtgg gtcaatcaag gtggttatca aacttactat
      841 gtgtggaatc cttggtataa ctacccaact gtaataagtg caaatgcagg accagttaca
      901 attcctgtac ctggaggtgg ttttacttgg gacaatacca ttacaaattg gtaaataaac
      961 ccattgcttt agttatgggt ctagtgttag ttcttttctt aactagttgt tcaaaaaaac
     1021 aagaaataca aaagactgat ctgattcctt ttctaggaac ttggcaaact aaagatcatt
     1081 cagaacgtct agtaatcact aatttaaata cttcaaaaaa tatagaacaa tataccatct
     1141 tagtaaaaga gaacaatcat aaaattcaaa tcattgataa aaatttaaat ataaatgaac
     1201 aagttttcat ttacaaagca acaaataatt tactaacact gcgctctaat aaaaaacaat
     1261 tagattacac ttttagtttg gattctccaa aaaagctcgt atttattttg acaacgaatg
     1321 atgggacaga agggacagct aaaccaattg aattttttaa agctgattga tgaatagttg
     1381 tttgatatta caaaacaata atttcaccga aggtgaaaca agcgaaactt tacaaaaagt
     1441 ggctagcatt tgctagcctt ttttgtattg tggagcgtgg tttttgaggg ggattcaagg
     1501 gggagcttgc gcccctttga caagcggtta tttgcaccaa atacgtaggt atttggctag
     1561 caaatataga gcttgccaaa cactttagtg agttttgtag aaagtacctt taaaggtact
     1621 ttcacattac gaacgatacg tccgtaggac gtactgaaag ggtgggattt atgagcgaac
     1681 taatgcaaaa tttggctagc aaaaaaagtt aaaaaatata tgctaataat cgagcgaaat
     1741 gaacactttt tcaagtgagc gaatccgcca tgacaaagct gaagcagttt atttcagctt
     1801 tgtcatggcg tgtgcctaga cttttaaaaa agtcggcaca cgagcaaata tctttatcaa
     1861 gctctaattt gcgttttaag acgtttgaaa cgtctaagta tataaatata taagagtagg
     1921 tttaagagtg cttaaatcga attttagagg gcattcagac aactttaggg ttgttagggc
     1981 ttgccctgac cgcctgtaag gcgctttaag aacaagataa gggatttata ctaagactgt
     2041 cttaaaacgt ctcaaacgaa ggctcatagc ttctcaaaga gttccttatg aacattttta
     2101 gcaaaggagc cggaagcgac tgcgcagtat aatgtgagag cagagcgatc acaccttttt
     2161 aagcgactgt agggagtaag attcccagtt gagaaaaatg cgcgaatctg tttggagaaa
     2221 aaagaagtgg ttttttaggc gggaaatttt gtccccctct tttataatct ctttttaaac
     2281 ctctttttaa acctctttac cgtcggctat atccttactc tcccaaggga atgacgcttt
     2341 tatctacatc gttttgtctg tttatctaca tcgttttgtc tgtttatcta catcgttttg
     2401 tctgtttatc tacatcgttt tgtctgtttg tacattgaat tagtacatcg acgatgttaa
     2461 tataagatgt agataaacag gcattttgta tttcataacg tgtatctctt gtgcgagtaa
     2521 gaaaggagct attttaaata tgtctaatga aatcgtaaag tatcatcatg aattaaatac
     2581 aattccgttg cgaaaattta caccagtcga aatgaatttg ttcttttcta tcgtatcaag
     2641 aatgcgtgat gtaggtgata aaaaagtaca atttacattc gagcaattaa aagatttaag
     2701 caattataaa gcaactgcaa atgttcgatt catagatgat ttagaaacaa cgtatgacaa
     2761 attaatggat ttacgttttg gtagaagaag tgctgacggt ttgcaacgtg aacgttttgt
     2821 tttatttaat caatttaaaa tcgacggaaa atctgatatt ccttttgctg aaatacaagt
     2881 tcatgaaaaa gccttaccct tacttaataa tcttgaagaa tgggtgcgct attctctcca
     2941 acaattcaat gaattagaaa gcagttattc aaaaacaatg tttcgattac taaaacaata
     3001 cagaaccaaa ggtttcgctt atttttcaaa agaagacttt catgaattac ttgatattcc
     3061 taaaagttac aaccaaggta cgattgatca acgtgtgttc aatccaatac gacaagaact
     3121 aaccgcaatc tttaaaggtt taacaatcaa aaagaaatac ggaaaaggac ggggaaagcc
     3181 tgtcattggc tatcaattta catttaaacc tgagataaaa aaatcagacg actttaacaa
     3241 acatgcccca acaaaagaag aacaaaacaa agcattagaa ctagctaacc aacaagttca
     3301 atctgaaaaa gcacctactt cattacaaga aaaaatcaaa gaacaaaagc gaaaattgga
     3361 acttttacaa cagttagaaa agttagaaag agaacaaaat acccaaaata aagaaaataa
     3421 tgcacaaaaa tcagagataa attccgatat tccttcagaa ctaaaaaaag acttattaga
     3481 caatcttcaa aacttattca aagattgagg ggtttttaga ttttatgaca gaaaaaacaa
     3541 tcaaagaact tgctgaagaa ttaggagtta gtaaaacagc aattaacaaa aaagtttctg
     3601 acgaaaatcg aaaactttgg ttttcgaaaa tcggaaacaa gtttgtgatt aatgaaaccg
     3661 gacaaaaggc tataaaatca atgtttttta acgaaaacga aaactcaaat caacaactag
     3721 ttggcgaaaa aacgaaaacc gaaacccaca aaaacgccaa ccaagttccc gaattagaag
     3781 tcctttctct cctagaacaa cagttaaatc aaaaagatat gcaactacaa gaaaaagacg
     3841 agcaaataaa acaaatgcaa aaattactcg accaccaaca acaactcacc ctgcaagcca
     3901 accaacaaat cgagaaactg caggaacaac tacagttgac ttatacggaa gaatcttcgg
     3961 aaaataaatc aacgactctt tctgaagaaa cagaatcgat agaaaaacaa tcaaagacgg
     4021 agaaaaaatg gtggcaattc tggcaataaa accagcaatt taaattaata aaaattgctg
     4081 gttttattct tctttttgct tttgcgagca gagcaacatg gacccatgtt gcgatatttt
     4141 ggtggcgccc caatccccgt tttttcgttg aatcttactc ggactgcact cgttttacag
     4201 ctgatttttc tgaattttga aagagcataa ggaaacgtgg tatcactttc ttacgaaagg
     4261 tgctagatag gctgtgccta tcacgtttct cagaaaaaaa tttgctatca cttttttgcc
     4321 attgtggcta ggctatgtat agtgttttgg cgaaaaatag ctatacaaat actatatttg
     4381 tatggtatac ataaattata cgctgatacg aaaggaaaat ttccatggac attttagttc
     4441 gaaatatcaa tcccaaaatt attgcaagaa tagataaacg ttgtcaggaa ctcacaacca
     4501 aaacgggcaa aaaatggagt cgaaataaat atctaaaagt tctaatcgaa agtgattttg
     4561 accgtcaact tatgaattac aaaaaagatc aattcgattt attactcgaa aaatttattg
     4621 ccattcaaac agaaaatacg aacatactga atgactatgt tcacacaaac aaccaactca
     4681 ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa acacgtaacc
     4741 ctttatccca gtcacgttga cgttttagat tccatcatcg aaaaaaatcc agacgtcaac
     4801 aattattcag aagccattcg ttttttatgt atgagttatg aacctgatac caatacaacc
     4861 acaaccagta accaagcaaa actcaatgcc atgggaaaag aaatttctat catgacagaa
     4921 atcatggcag aatttgctga tttatatcta aaagatactg gtgttcttat cggtacaaat
     4981 tctaaagtgt atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc ttcccgacga
     5041 aatcaaccca aaaatcgtca aaaagaaacc aatcaaacct ttacttctgg aaattttgac
     5101 ccaacaaact ttctaaaaag ataaaaaaag aaaccgatcc ctaaaaaaat tcctcgattt
     5161 ctttttaggg atcagtcttc cagcaagatt tgcaagttgg taccaacttg cg
//
LOCUS       DAPBCF010000111         5181 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.115, whole genome shotgun sequence.
ACCESSION   DAPBCF010000111 DAPBCF010000000
VERSION     DAPBCF010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5181
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.115"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..369)
                     /locus_tag="RD508_002813"
     CDS             complement(<1..369)
                     /locus_tag="RD508_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7737323.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYSFEEKIP
                     HFSTFGKNYVRRFRETTVFED"
     gene            complement(359..1558)
                     /locus_tag="RD508_002814"
     CDS             complement(359..1558)
                     /locus_tag="RD508_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDT7737324.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENAQTVDKVHFMDDVYSLFFYNRFMKTNA
                     RSDSYDV"
     gene            complement(1688..3064)
                     /locus_tag="RD508_002815"
     CDS             complement(1688..3064)
                     /locus_tag="RD508_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7737325.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(3064..3720)
                     /locus_tag="RD508_002816"
     CDS             complement(3064..3720)
                     /locus_tag="RD508_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7737326.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(3730..5007)
                     /locus_tag="RD508_002817"
     CDS             complement(3730..5007)
                     /locus_tag="RD508_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7737327.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            complement(5026..>5181)
                     /locus_tag="RD508_002818"
     CDS             complement(5026..>5181)
                     /locus_tag="RD508_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDT7737328.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
BASE COUNT         1625 a          951 c          655 g         1950 t
ORIGIN      
        1 atcctcaaac accgtcgttt ctctaaatcg gcgaacataa ttctttccaa aagttgagaa
       61 atgggggatt ttctcctcga aggagtagcc taaaaaccag cggtaagcga cattggtatc
      121 gacttcctta atggtttgtc gcatggaacg gataccgaat aaatactgaa taaacaccaa
      181 tttgatcaga atcactggat cgatacttgg gcgacctaaa tcggagtaag tggcttcgac
      241 gattggataa ataaattcaa aatcaagcgc ggcatcaatc tttcgaacga gatgatcttg
      301 aggaactaga tcatcaatcg taagcatcgc aaattgattt ctaccattcg tattgttttt
      361 agacatcata gctatcactc cttgcattcg ttttcataaa tctattataa aagaaaagac
      421 tgtagacatc atccataaaa tggactttgt ctacagtctg cgcattctca ttagagaacg
      481 ctcctttttt tgtgactttt ctgaagctgg agtggacact ttcaaccgca ttggtagtgt
      541 acataatttt tcgaatggca ctaccataat caaatagttg ttcaacatga gaaaagtttc
      601 gtttgcatac atctactgca ccagaataat gagaccaccg attttgaaaa ctgtcgaagg
      661 cagcgtgtgc agcgtttaaa gaagaagcac tgtagaattt tttcatgtct cgacagactt
      721 ccttataatc cttacttggg aggtatcgta acgcatttcg aacaagatga acaatacagc
      781 gctgcacaat gacagaagga aaaattgctt ttgcgccttc tttgagaccg gaaacaccgt
      841 ccatcgaaat gaaaaaaaca tcttctacac cacgtacttt cagttcatca aatacttgca
      901 tccagcgatt tttagattct gtttgattga gccataggcc taaaatctcc ttgtttcctt
      961 taagatcata gccaagaatg gtgtacacag catattcttt agcttcatag ttttcgcgta
     1021 aagtgacgta catacaatca acgaatagaa atgcataaca cttggctaat ggccgagctt
     1081 gccattcttc caattcagga aggacggcat ccgtgatatc agaaatcatt tcgtgggaaa
     1141 tatcaaagcc gtaaatatct tcaacggttg cggcgatatc gcattgactc attcctcgtg
     1201 catacatgga aagaacctta ccttcgatgt cggagacatc tcgttttcta ttaggaatca
     1261 actcaggttc aaaagaagcc tcccggtctc tgggaacatc aatgtttact ttaccaaagc
     1321 tcgttttaag cgtcttattg ccataaccgt ttcgtcgatt gtcatgtttc tttggctctt
     1381 tagaatgggc gtcataccct aaatggttat tcaattctcc ttgaagcatt ttttcaaata
     1441 agggaccaaa cacatctttt aaaacatctt gcatatcctc tacagattcg ggttgataag
     1501 tattcaaaat ggattcagct aacttctcag catcaggatt tcttttcttt ctagccatcg
     1561 tgtaatcacc tcttgatctt attttagaaa aataaaaacc gtgaagcaac cacccgccta
     1621 ggattgatgg ttacttacac ggtttatatt acactctcat ttttggtgct aaaaagcacc
     1681 gaaaatttta attattgtca attaataatt cttttggatt ccttcttaat atattgaatg
     1741 aagaaataat caatgataca agaagtacta aactcataaa tataactaca taaatcatga
     1801 atttaggtaa tacattgata tctaaacttg ataatgtctt gttaaatcct tcagcttctg
     1861 ccccaccacc taattggcta gatgcagatt gtttagctat ttgtttagct atatcaccag
     1921 taaccttatt caatatatta ttcccaagct tgtcagctgt atattgagct aagaaatagg
     1981 aaccaacgaa tgcggggatt gatataaata ccatctcaat taggaattga ccaaaaattt
     2041 ctaattttga tatacctaat gatagtaata ctgctatttc tttctttcta gcattcatcc
     2101 ataagaataa taataatgaa actacaactc ctgcaaatat taatgagcca aaaaataatt
     2161 tatttgaaat tgagtaaata cctgatatag attgttgtaa tgcagggtaa tttgatgaac
     2221 ttttaatcaa attatattct ctccaattta tatctaattt cccaagatct tttattacac
     2281 tatcaagatt cttatcacct tttacaaaga atgttgcatc ttggtataca gctgtatctt
     2341 cggtattacc ataaacttta gcagctgtat gaatatcagt gattaatgta ttttcgtata
     2401 gttcttgtgc tgcacttact ccaccgctat tatgcccatc gaatagacct ttaatttcta
     2461 cttctactgt ttcatctgca cctttctcat tatcagcatc aaataaatta gattttattt
     2521 ttatcttatc tccaacttta aggttatttt tttcagctaa atctttatgc attaagattt
     2581 tatttttatc ttcattttct aaatgctttc cttctactaa tttatatgct tctgatacaa
     2641 attttgtttc ttttgttgag tcgttaaccc cagttaacat aactgttctt ttaaaattct
     2701 ttgctctttc aggtgattga ttcgcaagag tctcttgagt ttcaataata tcataatcaa
     2761 ctaaatctgc aacactgttt attcttttta cataggagtc tatactatct gtttgagata
     2821 tctttttaat atcttcacct tttacatttc ccccacctct aggtgttcct ggatttactt
     2881 gtctatttat ctccatagaa aaactatttg ttatattagc aaatgtttct tttgaagctc
     2941 tgtccgtagc atctttaata gataaactaa tgagacttaa agttgacata gataaaataa
     3001 ctaatatgat aattaatgat tttaaacttt ttctagttac ataagcaaat gcatttttta
     3061 tcattattca acctccaaat tcattttatt tacttttttc aactttttac cacttagttc
     3121 taaaatgata tccgcagaat ctgctacttc cttactatgt gttacaacta ttacacattt
     3181 atttctatct ttagctaatg tctttaatat attaattatt tctccagcag taacactgtc
     3241 tagattacca gtaggctcat cagctagtat tattggagca tctgatacca atgctctagc
     3301 aatagctact ctttgttgct gtccaccaga taatttcata acatttcttt ttatttgttt
     3361 tttatctaaa cctagttcaa acaagatact ttcatctgct gatttattta ctaatctaat
     3421 attttcaatt ggtgataaat aatctattaa attatagttt tgaaatacta aagatatatt
     3481 attttttcta tgattactat atcctttatt ttgtatatct tcattcttaa acaatatttt
     3541 tcctgtttga ggtttatcaa gtccagcaag taaggaaaga agtgtagatt ttcctgttcc
     3601 tgactttcct actatcgcat aaaacttccc aagttcaaat ttttgattta ctcctgacaa
     3661 aactttttct ttagaatttg cataactata tgctacattc tttatttcta atatatccat
     3721 tattttctcc taacttattt ttgataagat ttctttaggc ttcttgatta acattaatga
     3781 agaagcaaat acaactgata aaacaataat acttattaat attaaataac tttgtccaag
     3841 tgttgttata tttgacataa aactactatt atttattaaa cttccaccgg aaatcattga
     3901 atcctctgag ttaatgaatc catctacaat tacttttagt aatacatttc ctaaaaataa
     3961 ggaagatatt atacttggta tcgatatgaa tattaactcg aatataaatt gcattataat
     4021 ttgtatctta gatgttccaa tagataagaa tatacctatt tcataaattc tttcccttaa
     4081 ccatagaatc aagattaatg aaagaacaac catcccacct aacataatag aataagtcat
     4141 tacttttatt atatatttta ttccactcac tgactctaaa gactcttcaa acgcattaga
     4201 atctttttca acaaaatact ttgactcatc aattttaagc tctttcaatt tgtttaaggc
     4261 taagtctgta gattctgcac taccagaata cattaaaatt ttatttgcaa tttcattatt
     4321 ttctgaattg tttaatatct cttggcttgt tgaataatct acaaacacca tattttcact
     4381 aaaatcagaa gataatcctg tatatgtttc ctgtttttta ccagaaaaga tccctataat
     4441 tttaaattta tgacttttta tttttccact tttttcaata tctagtaatt caagatcaac
     4501 ttcatcacct aattttagat tgttttgttt agcaaattct tcatgaacaa taattgaatt
     4561 cttatcattt tcttctatat ttttaccttc tttaattgta aatactccac tactaaataa
     4621 aatatttctt ttagtattat ttgtagcttc gagtgaaaca acattcttaa attcgtcaga
     4681 taaatcttct ctatttattc tttgttctcc gctaactact ttagcatctt ttagttttgc
     4741 taatccatca tattgaatta ttttttcttc aatttctttt aatttttcaa tatctttaaa
     4801 ttgattaaca ttaaaatatt taccatcttt ttttgttatt gatattgaag aattagaact
     4861 ttcatataaa gccttttcta tttcattgct tgatttcatt attgttaaac aagaatacaa
     4921 gcaagaaaga actatagtta atatgataaa aattattaaa gttctatttt tctttcttgt
     4981 aatatatgct atagcatttt ttatcacttt cctaactact cctctctatt ttcttactcc
     5041 ataactaatt gcatccactg gacaagcatt tttacatcgt ccacatctga tacactccag
     5101 atgattgcaa ttctcaactg aatctttatt catttggcaa acttttttac attttccaca
     5161 attaatacac ttatccttat c
//
LOCUS       DAPBCF010000112         5092 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.116, whole genome shotgun sequence.
ACCESSION   DAPBCF010000112 DAPBCF010000000
VERSION     DAPBCF010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5092
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.116"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            209..493
                     /locus_tag="RD508_002819"
     CDS             209..493
                     /locus_tag="RD508_002819"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDT7737329.1"
                     /translation="MSQYQFETMAHLELECFDYVNWWNHHRIHSSLGYKTPIEVLCGG
                     WRSEPLIMSKNRLPSVRAAYFIQSEHAAKKTDLRRLVVKGNWIWCHKQTL"
     gene            complement(663..1058)
                     /locus_tag="RD508_002820"
     CDS             complement(663..1058)
                     /locus_tag="RD508_002820"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HDT7737330.1"
                     /translation="MKVTMLKGKIHRATVEQAELDYVGSITVDMNLLEAAGIYEYEKV
                     QIVDVNNGNRFETYTIAGERGTGMICLNGAAARCVSTGDKIILMAYCELNENEVKDHR
                     PKVVFVDDNNKVERVTSYEKHGRLSDIIL"
     gene            complement(1068..1916)
                     /locus_tag="RD508_002821"
     CDS             complement(1068..1916)
                     /locus_tag="RD508_002821"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDT7737331.1"
                     /translation="MVIFKTVNDVRSQVKEWKKQGLKVGLVPTMGYLHEGHESLIRKA
                     SKENDKVVVSIFVNPTQFGKNEDLGSYPRDLERDIEVCTRGRATAIFNPEVEEMYCDN
                     ASTFVNITGLTEGLCGASRPIHFRGVCTVVSKLFNIIPADRAYFGEKDAQQLAVIKRM
                     VRDLNIDIDVVGCPIIREEDGLAKSSRNTYLSLEERSSATILNKSLTLAKEALNNGER
                     DSLKIIEIISKNINTYNLAKIDYVEVVDSLSLQRVNYIEKSVLVAIAVFIGKTRLIDN
                     FTFELQ"
     gene            complement(1931..2758)
                     /gene="panB"
                     /locus_tag="RD508_002822"
     CDS             complement(1931..2758)
                     /gene="panB"
                     /locus_tag="RD508_002822"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDT7737332.1"
                     /translation="MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGD
                     SLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGR
                     LIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEA
                     AKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQD
                     MLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY"
     gene            complement(2770..3630)
                     /locus_tag="RD508_002823"
     CDS             complement(2770..3630)
                     /locus_tag="RD508_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HDT7737333.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQEIKNYQIKNKLICHCSGAISS
                     DIFSNIQDYGAYGYSVHPMFSISDKYNSYKKLKKSFITIEGDEKYAKFLCDFFKKLGN
                     STVIVSKENKSLYHAASVVSSNLVLGLINTSVTYLIQCGFTEKMAIEALYPLIEFNIR
                     NIKEKGIIESLTGPVERCDISTIKGHCEVLSDEDRALYMLLSKNVLEIAMLKNINRDY
                     SELEKYLGES"
     gene            3868..5037
                     /locus_tag="RD508_002824"
     CDS             3868..5037
                     /locus_tag="RD508_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDT7737334.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRDRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT         1644 a          952 c          680 g         1816 t
ORIGIN      
        1 tacggaaaga agttctgcac cttataaaat ttgtcaaaaa aactgttgcc attccaactc
       61 ttccatacgg atcgtggaaa agaatttgat aatgaattga ttgatcttat cttagaaaca
      121 tttggcattc aacgctcctt gagtaagcct ggatgtccat atgattgccg tttcagaagc
      181 gacttacaaa gcttttaaga cggaatttgt gagtcaatat caatttgaaa cgatggcaca
      241 cttagaatta gaatgttttg attatgtcaa ttggtggaat catcatcgga tccatagttc
      301 tcttggttat aaaacaccaa ttgaggtact atgcggaggt tggcgtagcg aacccttgat
      361 aatgagcaag aatcggttac cttctgttcg agcggcttat tttattcaaa gtgagcacgc
      421 cgctaagaaa accgatttga ggaggctcgt tgtcaaggga aactggatat ggtgtcataa
      481 acagacctta taatttttgt ctagaaaagt gttgccattc catgtagaca tcatccataa
      541 aatggacttt gtctacagtc tgtatcttct ctttttgtgt ctactttatt gacatctatc
      601 caattagtaa tcaataaata tttcaataat agtctagcta tatataaata acattacaaa
      661 acctaaagaa ttatatctga taaccttcca tgtttttcat atgatgttac tctttcaact
      721 ttattattat catcgacaaa aacaacctta ggtctatgat ccttaacctc attttcattt
      781 aattcacaat atgccattaa aattatttta tctccagttg atacacatct agctgcagct
      841 ccattcaagc aaatcatccc tgttcctctc tctccagcta ttgtataagt ttcaaatcta
      901 tttccattat taacatcaac tatttgtact ttttcatatt catatattcc tgctgcttct
      961 aataaattca tatcaacagt aatacttcct acataatcta actcagcttg ttcaactgta
     1021 gctctatgta tttttccttt taacattgta actttcatta tagcccccta ttgtaattca
     1081 aatgtaaaat tatctattaa tcttgttttt cctataaata ctgctattgc aactaaaact
     1141 gatttttcaa tataatttac tctttgtaat gataaagaat caacaacttc tacataatca
     1201 atctttgcca aattataagt atttatattt ttacttatta tctcaattat ttttaagctg
     1261 tctctctctc cattatttaa agcttcctta gctaaagtta aagatttatt taaaatagta
     1321 gctgaagatc tttcctctaa acttaagtat gtgtttctag aacttttagc tagtccatcc
     1381 tcttccctta taattggaca ccctacaacg tctatatcaa tattaaggtc cctaaccatt
     1441 cttttaatta cagctaactg ttgtgcatcc ttttctccaa aataagctct atctgctggt
     1501 attatgttaa ataatttact tacaacagtg caaacccctc taaaatgtat tggcctacta
     1561 gctccacata aaccttctgt taatccagtt atattaacaa aagtacttgc attgtcacaa
     1621 tacatctctt caacttcagg attaaatatt gctgttgctc tacctcttgt gcatacttct
     1681 atatctcttt ctaagtctct tggataacta cctaaatctt catttttccc aaactgagtt
     1741 ggatttacaa agatacttac aacaacttta tcattttctt ttgatgcttt tctaattaaa
     1801 ctttcatgac cttcatgtaa atatcccata gtaggaacta atcctacctt taagccttgt
     1861 tttttccact cttttacttg acttctaaca tcatttactg ttttaaatat aaccatattt
     1921 cttgcccctt ttaatataat ttttctaaaa catcatcact tattttaaac ccatgttctg
     1981 gacctggaaa aactccatct tttacttcct ctatatattt tgtaaatgct ttattcatct
     2041 cttctgataa attagcatat ttcttcacaa atttaggggt aaaatcacta tacatcccca
     2101 acatatcttg atatacaaga atttgtccat cacaccctgc acctgctcca ataccaattg
     2161 taggtattga tatctcttta gaaattaact ctgcaagctt agttggaaca cattctaaca
     2221 ctacagcgaa tgctcctgct ttttctacag ctttagcagc tcttattaat tctttagcag
     2281 cttccttgtc ctttccttgt accttaaatc ctccaaatgc attaacagat tgaggtgtta
     2341 aacctatatg cgccataaca ggtatagaag cctttactat agcctctatt ttatcgcata
     2401 cttctatccc tccttctaat ttaacaacct gagctcgtcc ttcttttatt aatcttcctg
     2461 cattaactac tgaatcatat actgaagttt gataagacat aaatggcata tctgcaacaa
     2521 ctaaagtgtt cttagctcct cttgtaactg ctctagtatg atgaatcatg tcttccattg
     2581 ttactgaaag tgtatcttca tgtcctagac ataccatacc aagagaatct cctactaata
     2641 ttccatttat cccagcttca tcaattattt ttgctgttga atagtcataa gctgtaagca
     2701 ttgttaattt ttcatttctt aatttagatt ctttaaatgt aactgctgta tttttcatct
     2761 atttctctcc taactctctc ctaaatactt ttctaattca ctataatctc tattaatatt
     2821 ttttaacata gctatctcta atacattttt tgataatagc atatataaag ctctgtcttc
     2881 atctgataaa acttcacagt gacctttaat tgttgaaata tcacaacgtt caactggccc
     2941 tgtcaaactt tctataattc ctttttcttt tatatttcta atattaaatt caattaatgg
     3001 atataaagct tcaattgcca ttttttcagt aaatccacat tgaattagat atgtaacgct
     3061 tgtattaata agtcctagca caaggttact agatactact gatgcggcat gataaagaga
     3121 tttattctcc ttagatacaa ttacagtact attacctaac tttttgaaga aatcacataa
     3181 aaactttgca tatttttcat cgccttcaat tgttataaaa gattttttta attttttgta
     3241 tgaattatat ttatctgata ttgaaaacat aggatggaca gaatagccat aagcaccata
     3301 gtcctgtata tttgaaaaga tatctgaaga tattgcacca ctgcaatggc agattaattt
     3361 gtttttgatt tgataatttt taatttcttg ccatacctcc tgaatttgac catcaggagt
     3421 cgtaatgaaa atagtatcat tttcatctac taattctctt aagtttaaat attgtttact
     3481 agatgtaaaa ttcgaagctg ctaatgacga gtcttcgctt ttactataaa atcctgttac
     3541 ttgtatttta tgttcctgga aatacttccc gaatgaacaa cctaccttgc cggctccaat
     3601 aaaaccaacg ttcataatta tcacctccat aaagaagtga gactacaagt cccattctta
     3661 cgatatgagc ttaaaaataa aaattaaatc aaatatacag tatggttttt tcaaatatca
     3721 tccatagtta atttatcata atatcccata ttttaaaata aaagatagcg taaaatattt
     3781 tgtgtaaata gaaatttagg gtagaaaaaa aagtccattc tgtaaaatta aagttaccac
     3841 acagaaattt tataggagga ctttctcatg actaaattta ctatagaaat tatgcaaaca
     3901 ctactcaata aaggggattt agatgaatta tttcaggatc atttagagcg agcgattaat
     3961 tcacttctac aagcagagct aactgctttt ttagattacg aaaaatatga tcgaaatgga
     4021 ttcaattcag gaaattcccg taacgggaat tattcacgta catttaaaac agaatatggc
     4081 gagttgaatt taactattcc tagagatcgg aatggcgaat tttctcaaca aacactacca
     4141 gcatataagc gaaccaatga ttcattagaa acgaccatta tccaattatt tcaaaaaggc
     4201 attactatgg ctgaaatctc caaattaatt gaaaaaatgt atggtcatca ctatacgcca
     4261 caaacaatct ccaacatgag taaattggtg gctgaagatg ttttagcttt taaagaaaga
     4321 acgttagaag ccaattattc cgttatattt atggatgcga cgcatatccc tgtgaagcga
     4381 cagactgttt cgaaggaagc agtgtatatt acgattggta ttcgtttgga tggaaccaaa
     4441 gaagttcttg ggtttactat tgccccaact gagtctgctt atatttggaa agaagttctt
     4501 caagatctta gaaaacgtgg gttagaagaa gttttattag tagtgacaga cggattaagc
     4561 tgtattgaag aaagtatcca tagtgtgtat ccgaatgccc aatttcaaca atgttgtgtg
     4621 catgtatcta gaaatatcgc tcataaagtt cgtgttcgag atcgaaaaga aatttgtgag
     4681 gatttcaaat tggtttacca agcgaattca aaagaagagg cattggatca catcgacttt
     4741 atgactagga aatggaaaaa gcagtatcca agagtcgtca atttactctt gaatcctgcc
     4801 ctattaacct tttataattt ccctcacgcc atcagacgaa caatttattc gacgaacctg
     4861 attgaaggct ttaataagca gctaaaacga tatactcgaa gaaaagaaca attccctaat
     4921 gaagaatctc tagagagatt cttcatttct caatttaatc aatataacca aaaattttta
     4981 ggtagaattc acaagggatt taaagaaatt caggatacat tagagtcgat gatttaactg
     5041 taattaacag aatggatttt ccatttacac ataattcttg acgctaccat tt
//
LOCUS       DAPBCF010000113         4931 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.117, whole genome shotgun sequence.
ACCESSION   DAPBCF010000113 DAPBCF010000000
VERSION     DAPBCF010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.117"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            85..972
                     /locus_tag="RD508_002825"
     CDS             85..972
                     /locus_tag="RD508_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDT7737335.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="RD508_002826"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="RD508_002826"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDT7737336.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="RD508_002827"
     CDS             2274..2720
                     /locus_tag="RD508_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDT7737337.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="RD508_002828"
     CDS             2993..4345
                     /locus_tag="RD508_002828"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HDT7737338.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="RD508_002829"
     CDS             4516..4803
                     /locus_tag="RD508_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737339.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1393 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt t
//
LOCUS       DAPBCF010000114         4859 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.118, whole genome shotgun sequence.
ACCESSION   DAPBCF010000114 DAPBCF010000000
VERSION     DAPBCF010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.118"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            59..754
                     /gene="vanR"
                     /locus_tag="RD508_002830"
     CDS             59..754
                     /gene="vanR"
                     /locus_tag="RD508_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HDT7737340.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            732..1886
                     /locus_tag="RD508_002831"
     CDS             732..1886
                     /locus_tag="RD508_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HDT7737341.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2101..3069
                     /locus_tag="RD508_002832"
     CDS             2101..3069
                     /locus_tag="RD508_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HDT7737342.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3062..4093
                     /gene="vanA"
                     /locus_tag="RD508_002833"
     CDS             3062..4093
                     /gene="vanA"
                     /locus_tag="RD508_002833"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HDT7737343.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4099..4707
                     /locus_tag="RD508_002834"
     CDS             4099..4707
                     /locus_tag="RD508_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HDT7737344.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(4767..>4859)
                     /locus_tag="RD508_002835"
     CDS             complement(4767..>4859)
                     /locus_tag="RD508_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7737345.1"
                     /translation="RGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT         1494 a          934 c         1133 g         1298 t
ORIGIN      
        1 ttcggcccta taatctgata aattattaag ggcaaactta tgtgaaaggg tgataactat
       61 gagcgataaa atacttattg tggatgatga acatgaaatt gccgatttgg ttgaattata
      121 cttaaaaaac gagaattata cggttttcaa atactatacc gccaaagaag cattggaatg
      181 tatagacaag tctgagattg accttgccat attggacatc atgcttcccg gcacaagcgg
      241 ccttactatc tgtcaaaaaa taagggacaa gcacacctat ccgattatca tgctgaccgg
      301 gaaagataca gaggtagata aaattacagg gttaacaatc ggcgcggatg attatataac
      361 gaagcccttt cgcccactgg agttaattgc tcgggtaaag gcccagttgc gccgatacaa
      421 aaaattcagt ggagtaaagg agcagaacga aaatgttatc gtccactccg gccttgtcat
      481 taatgttaac acccatgagt gttatctgaa cgagaagcag ttatccctta ctcccaccga
      541 gttttcaata ctgcgaatcc tctgtgaaaa caaggggaat gtggttagct ccgagctgct
      601 atttcatgag atatggggcg acgaatattt cagcaagagc aacaacacca tcaccgtgca
      661 tatccggcat ttgcgcgaaa aaatgaacga caccattgat aatccgaaat atataaaaac
      721 ggtatggggg gttggttata aaattgaaaa ataaaaaaaa cgactattcc aaactagaac
      781 gaaaacttta catgtatatc gttgcaattg ttgtggtagc aattgtattc gtgttgtata
      841 ttcgttcaat gatccgaggg aaacttgggg attggatctt aagtattttg gaaaacaaat
      901 atgacttaaa tcacctggac gcgatgaaat tatatcaata ttccatacgg aacaatatag
      961 atatctttat ttatgtggcg attgtcatta gtattcttat tctatgtcgc gtcatgcttt
     1021 caaaattcgc aaaatacttt gacgagataa ataccggcat tgatgtactt attcagaacg
     1081 aagataaaca aattgagctt tctgcggaaa tggatgttat ggaacaaaag ctcaacacat
     1141 taaaacggac tctggaaaag cgagagcagg atgcaaagct ggccgaacaa agaaaaaatg
     1201 acgttgttat gtacttggcg cacgatatta aaacgcccct tacatccatt atcggttatt
     1261 tgagcctgct tgacgaggct ccagacatgc cggtagatca aaaggcaaag tatgtgcata
     1321 tcacgttgga caaagcgtat cgactcgaac agctaatcga cgagtttttt gagattacac
     1381 ggtataacct acaaacgata acgctaacaa aaacgcacat agacctatac tatatgctgg
     1441 tgcagatgac cgatgaattt tatcctcagc tttccgcaca tggaaaacag gcggttattc
     1501 acgcccccga ggatctgacc gtgtccggcg accctgataa actcgcgaga gtctttaaca
     1561 acattttgaa aaacgccgct gcatacagtg aggataacag catcattgac attaccgcgg
     1621 gcctctccgg ggatgtggtg tcaatcgaat tcaagaacac tggaagcatc ccaaaagata
     1681 agctagctgc catatttgaa aagttctata ggctggacaa tgctcgttct tccgatacgg
     1741 gtggcgcggg acttggattg gcgattgcaa aagaaattat tgttcagcat ggagggcaga
     1801 tttacgcgga aagcaatgat aactatacga cgtttagggt agagcttcca gcgatgccag
     1861 acttggttga taaaaggagg tcctaagaga tgtatataat tttttaggaa aatctcaagg
     1921 ttatctttac tttttcttag gaaattaaca atttaatatt aagaaacggc tcgttcttac
     1981 acggtagact taataccgta agaacgagcc gttttcgttc ttcagagaaa gatttgacaa
     2041 gattaccatt ggcatccccg ttttatttgg tgcctttcac agaaagggtt ggtcttaatt
     2101 atgaataaca tcggcattac tgtttatgga tgtgagcagg atgaggcaga tgcattccat
     2161 gctctttcgc ctcgctttgg cgttatggca acgataatta acgccaacgt gtcggaatcc
     2221 aacgccaaat ccgcgccttt caatcaatgt atcagtgtgg gacataaatc agagatttcc
     2281 gcctctattc ttcttgcgct gaagagagcc ggtgtgaaat atatttctac ccgaagcatc
     2341 ggctgcaatc atatagatac aactgctgct aagagaatgg gcatcactgt cgacaatgtg
     2401 gcgtactcgc cggatagcgt tgccgattat actatgatgc taattcttat ggcagtacgc
     2461 aacgtaaaat cgattgtgcg ctctgtggaa aaacatgatt tcaggttgga cagcgaccgt
     2521 ggcaaggtac tcagcgacat gacagttggt gtggtgggaa cgggccagat aggcaaagcg
     2581 gttattgagc ggctgcgagg atttggatgt aaagtgttgg cttatagtcg cagccgaagt
     2641 atagaggtaa actatgtacc gtttgatgag ttgctgcaaa atagcgatat cgttacgctt
     2701 catgtgccgc tcaatacgga tacgcactat attatcagcc acgaacaaat acagagaatg
     2761 aagcaaggag catttcttat caatactggg cgcggtccac ttgtagatac ctatgagttg
     2821 gttaaagcat tagaaaacgg gaaactgggc ggtgccgcat tggatgtatt ggaaggagag
     2881 gaagagtttt tctactctga ttgcacccaa aaaccaattg ataatcaatt tttacttaaa
     2941 cttcaaagaa tgcctaacgt gataatcaca ccgcatacgg cctattatac cgagcaagcg
     3001 ttgcgtgata ccgttgaaaa aaccattaaa aactgtttgg attttgaaag gagacaggag
     3061 catgaataga ataaaagttg caatactgtt tgggggttgc tcagaggagc atgacgtatc
     3121 ggtaaaatct gcaatagaga tagccgctaa cattaataaa gaaaaatacg agccgttata
     3181 cattggaatt acgaaatctg gtgtatggaa aatgtgcgaa aaaccttgcg cggaatggga
     3241 aaacgacaat tgctattcag ctgtactctc gccggataaa aaaatgcacg gattacttgt
     3301 taaaaagaac catgaatatg aaatcaacca tgttgatgta gcattttcag ctttgcatgg
     3361 caagtcaggt gaagatggat ccatacaagg tctgtttgaa ttgtccggta tcccttttgt
     3421 aggctgcgat attcaaagct cagcaatttg tatggacaaa tcgttgacat acatcgttgc
     3481 gaaaaatgct gggatagcta ctcccgcctt ttgggttatt aataaagatg ataggccggt
     3541 ggcagctacg tttacctatc ctgtttttgt taagccggcg cgttcaggct catccttcgg
     3601 tgtgaaaaaa gtcaatagcg cggacgaatt ggactacgca attgaatcgg caagacaata
     3661 tgacagcaaa atcttaattg agcaggctgt ttcgggctgt gaggtcggtt gtgcggtatt
     3721 gggaaacagt gccgcgttag ttgttggcga ggtggaccaa atcaggctgc agtacggaat
     3781 ctttcgtatt catcaggaag tcgagccgga aaaaggctct gaaaacgcag ttataaccgt
     3841 tcccgcagac ctttcagcag aggagcgagg acggatacag gaaacggcaa aaaaaatata
     3901 taaagcgctc ggctgtagag gtctagcccg tgtggatatg tttttacaag ataacggccg
     3961 cattgtactg aacgaagtca atactctgcc cggtttcacg tcatacagtc gttatccccg
     4021 tatgatggcc gctgcaggta ttgcacttcc cgaactgatt gaccgcttga tcgtattagc
     4081 gttaaagggg tgataagcat ggaaatagga tttacttttt tagatgaaat agtacacggt
     4141 gttcgttggg acgctaaata tgccacttgg gataatttca ccggaaaacc ggttgacggt
     4201 tatgaagtaa atcgcattgt agggacatac gagttggctg aatcgctttt gaaggcaaaa
     4261 gaactggctg ctacccaagg gtacggattg cttctatggg acggttaccg tcctaagcgt
     4321 gctgtaaact gttttatgca atgggctgca cagccggaaa ataacctgac aaaggaaagt
     4381 tattatccca atattgaccg aactgagatg atttcaaaag gatacgtggc ttcaaaatca
     4441 agccatagcc gcggcagtgc cattgatctt acgctttatc gattagacac gggtgagctt
     4501 gtaccaatgg ggagccgatt tgattttatg gatgaacgct ctcatcatgc ggcaaatgga
     4561 atatcatgca atgaagcgca aaatcgcaga cgtttgcgct ccatcatgga aaacagtggg
     4621 tttgaagcat atagcctcga atggtggcac tatgtattaa gagacgaacc ataccccaat
     4681 agctattttg atttccccgt taaataaact ttggttctgt tgcaaagttt taaataaaga
     4741 ataaaatccc ttacggtatc tatgatttaa gctgggattc ccaataatac cttgatttca
     4801 gtacagaccg aaaacccgaa gagagtgcct tcttttcggg ttttcttata taatcctcg
//
LOCUS       DAPBCF010000115         4786 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.120, whole genome shotgun sequence.
ACCESSION   DAPBCF010000115 DAPBCF010000000
VERSION     DAPBCF010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4786
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.120"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..1614)
                     /locus_tag="RD508_002836"
     CDS             complement(<1..1614)
                     /locus_tag="RD508_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDT7737346.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFK"
     gene            complement(1777..2370)
                     /locus_tag="RD508_002837"
     CDS             complement(1777..2370)
                     /locus_tag="RD508_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737347.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            complement(2371..2703)
                     /locus_tag="RD508_002838"
     CDS             complement(2371..2703)
                     /locus_tag="RD508_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737348.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            complement(2753..>4786)
                     /locus_tag="RD508_002839"
     CDS             complement(2753..>4786)
                     /locus_tag="RD508_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737349.1"
                     /translation="GSPAFQIIQNNVIDVSTLLENDPNKVEHIPTDKRNALTAKNFKT
                     ANINGIITPKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAK
                     YVYTSGYRRYISSPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFE
                     TGQRMKSAIEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLT
                     IALFKGSQSVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHL
                     NDIRKNGFGHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYV
                     NERGLKGTAEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLK
                     DAYGEGQVNAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEE
                     GKNGQLPKTDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRS
                     VNSENEKRISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSR
                     LNQFKDNDQSFVHQSPAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTRE
                     AAPKPIQNVHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
BASE COUNT         1247 a         1006 c          785 g         1748 t
ORIGIN      
        1 tttgaagtct tgttcttcca tttgtttttc tttaattaaa cgtcgttgtc ttcttccttg
       61 aatcaatgcc tgattccaaa tcaacgtcat agccatgtac atttgacatt gttgtacccc
      121 acgatctaaa cctgtaatag agtcaatgtc aaaaaagacc aactgttgtt ggtcaaggtg
      181 tcgaatcgta ctatgaccat caaaaatcat gccatacgtc tcacataagg attctacgat
      241 ggattccatt tcttcttttc gattcttttt ctcttgggaa gcacctggta attccagttg
      301 tcctaaaaag tctaaaaatt ctttgaacgt cggataagct tctggatctt tccctgtgac
      361 ttgcgtctcc gtatttgaac gcgagtttga ggaagtgaaa ccgcgtggta ctgttccata
      421 ctcttcataa aaacgattta aataggtctt aaattctgct ttcatcgttc cttttagctg
      481 aggactcact aactgtacct gatagaccac tttgtctaag tgtgtttgat aggacgctgc
      541 ttcattgatc ttcaaatctt tgactgatcc atcgtcatat aaactggatg cttcatcata
      601 cgtccgtgtg gcaaatatct ctaaaggatt gatcattccg tcagatccgt ctaaacgcac
      661 cataataccg ttatattcct ttaagaaagg aataaagtct tttccctttt caaagcccca
      721 aataaagtct cctgcagcta aatgggcttc cgcgatcatt ttaagaacgg tcgatttacc
      781 agctcccatc attcctagaa gcaaggtatt ggtagacaac cgtacactat ttttatacgt
      841 cgcattccag acaaatgggc cgcctgtcat agtttcccca tattgtgtcc ctcctggatc
      901 ttttagcgtt tggtggtgga acgggaaacc tccgccaatg tttaacgatg gtagtgattg
      961 ccctttgata tttccgaacc attcagcttg ttcatcgaac atggtaaaca tcgattgcca
     1021 atctcgtttg gttttatgca gataagtcac cgcacgataa tccatccctt tgagattttc
     1081 gatcagttcc tgcgctcgtt catctacttc ttgaatcgtg tttccgtaaa catgtactct
     1141 cactttgact tgcttagaaa tttccccatt agaagtcaat ttacgagcat attccgctag
     1201 ttccaggtat tcttctgcgc ttttatttcg gtcagtcgct tttcgttcgt tatctgatcg
     1261 atcatttaat tcatctaagg cacgattgat ttgatcaatc actttttgct tttcatctgt
     1321 gctaacatcg agtgtggcca ctgtatgagg attgttcatg agattggcca accaaaaaag
     1381 cgtaggattt tttgtgtagt gataaactgt cacacatcgt gaataaccat taccatacgt
     1441 cacatattct tcatcaaaat ttaacccacc ttgtggcatc acttgtttta aaaaatctaa
     1501 atcataccct ttggatttta aaatttctat ttcccgattt cctagttgct ttaatggatc
     1561 aagtactttt tgatcatttt gtggtgaaaa agctgtttta attgcttcta acatgtacag
     1621 tcacctcttc ttgtttgatt ctttacttgg ttaaaagatt gcccttttcc caacttaccc
     1681 aggcttaaag tgtgaggaaa ttttctagtg gtctcttcct tcggaacatc tttttctaac
     1741 catatcaacg gatatttcat tctctcttct ccattcctac tcatcattca tattgttcat
     1801 tcgatacaga atcttgatca attctttttt gtagagtggt tttaacccta aaatgccact
     1861 agatcgcatt aactgacggt ttctggtttg taaatccttg attgtctttc cttcaatgac
     1921 gaaaaagaag cttaagtcag gacgttcttg ttctgctcgt ttcaattcct ggatttcttc
     1981 gactaatttc ttttcatatt tttttaatcg ttgtagattt cttcctaagg actgttccat
     2041 acgattttta tctaataatt gccgcttttg cacgatttgt tccgttagat ccgtctctgt
     2101 ggtcaaacta actaacttaa ttgttggcac atacgtacgc atgacggtgg tcaactgatt
     2161 cattcgttct agtttctctt gttcatttaa tccttccacg tctgtagaaa ctacacgata
     2221 ataacgttga aaatgatctt ctctagtaat taagactccc tcttctgtac aggatttata
     2281 cggaaataag tccaagatag agcgctcttc tggttttcca aactgcaaaa tggatttcct
     2341 ttcaactgaa ttttgtcctt tgactcgcat ttattcatcc tccttatacg taccatgata
     2401 atttcggtta ggatctaacg catgataatg gttcttgtcc gcaaaaaaaa tagactcgat
     2461 aatcgcaaaa atttgtcgtt gacctgggtt attatagggt cgccaaacaa tcactaacgc
     2521 tatcgcaatc cataagccat aattcaagag tgcaaaaaag agtggtaagt ggacaagatt
     2581 attgaccatt ttcgcccaaa aaaagcagcc accaagcgtt aatagatcta aaaagaaaaa
     2641 agcgaaaaac ttccattctc cactaaatct tggagggttt ttcatgttta tatatttatc
     2701 cataattgat ttctcctttt catataaaga aaaggcctaa cttgtaggcc ttttatggtt
     2761 tgatatcctg tttgatatcc ctcaatagtt gttctttcaa tgcattgttc ctgtttttag
     2821 tttctcttgt cacatttatt tttgttggtg cagtaaatgc cacatttgct ggcttgtaac
     2881 ctgtatgaac gttttgaata ggttttggtg cagcttctct tgtcacaaca ttttgaacgg
     2941 acgcattccc tgtctcacca ctttcagata aattgtaaga aacagttgtc agatttccat
     3001 tttcaggcaa acgacttggt ttcatttgaa cagtacctgc aggtgattga tgaacaaaac
     3061 tttgatcatt atccttgaat tgattcaaac gactatcttt cattggtaaa ttttgtgcct
     3121 taggtaaacc aattttcgtt gatttttcag ttccaacttc gattccatta tcatttggca
     3181 gaacgatgga atcctcatcc gtttgtactt cttgatttcg ttttggtaaa tctgaaatgc
     3241 gtttttcatt ttcggagtta acagatctat accgatattg ttctggatca gtttttggta
     3301 actgtccctc attttctgct ttgtcttctt gatttacttt tgataaatct gaaattcgct
     3361 tctcattttc aaggtcactg ttaggtttat agcgatattg ttctggatca gtttttggta
     3421 actgtccatt ttttccttct tctgaatttc tttcttctat ggaatttttc tcttcaatcg
     3481 aattttcatt agagtgcaac gcttcttggt gatctttgac tgaaggaatc actatacctt
     3541 cttgattttc tttttcggtt gttgtattag ctttcactgc tgcattgact tgtccttcac
     3601 catacgcatc ttttagtcct tctttgactt ctgaagcttt ttctttttgt ttttctagtg
     3661 cttcggatgg attcttcaca gcttcagcca attctttagc tctcgtgccg tctaatttct
     3721 cttctaaggt gtctttggct ttttctgtaa gatcttcagc tgttcctttt aacccacgtt
     3781 cattgacgta accaagacct tctgcggctt tagaaacacc atttttcgct ttcccgaaca
     3841 tttcggaaac tgttttctta ctattaggta cagttgtagc tttatcgtct gattgttctt
     3901 ccccgttatc aggggtaaca tcttttcgat ggccaaatcc atttttacga atatcattta
     3961 aatggcttaa accactctta ccagcacttg caaggttttt agctccgcta cccacatttt
     4021 tcgcaatatt tcctaaggca aacatgctaa gaagagaatt actgccgttt ttcagactcg
     4081 tatcaacgcc gaaaattttc gtaactgatt gagagccttt gaatagcgca atggttagta
     4141 caatcaaagc gacaacatac aagaatccat tgatctttcc tgccgcatgc aaatcaccaa
     4201 tacctgaaag cattaaggta tagattcgta attctaaaat tgtaaatgcc aataacaaga
     4261 aggattgaga aatatcttcg atagcacttt tcatccgttg tcctgtctca aagtccgttg
     4321 acgcggcaat cactaaatag aattttttaa ataccagctc aataatgcaa gtaacgatcg
     4381 taaataggat aaataaatag gccaccgcca aagaagattc accagctaaa ataatccctg
     4441 gactactaat gtatcgacga taccctgaag tataaacata tttggctaag ccttcatcac
     4501 tgatttgcac aggaatttct tttccattat catccagttc cagtcggtat tgtaacgctc
     4561 ttaaccgatc cttttgtaaa tctgataaac cactcttatc tttatccgcc atttctttag
     4621 cttgtttagg agtaataatc ccattgatat tcgctgtttt aaaatttttc gctgttaaag
     4681 catttctttt gtctgttggt atgtgttcta ctttgttcgg atcattttct agtaacgtac
     4741 tcacatcaat cacattattt tgaataattt gaaaagcagg tgaacc
//
LOCUS       DAPBCF010000116         4690 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.121, whole genome shotgun sequence.
ACCESSION   DAPBCF010000116 DAPBCF010000000
VERSION     DAPBCF010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4690
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.121"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(12..482)
                     /locus_tag="RD508_002840"
     CDS             complement(12..482)
                     /locus_tag="RD508_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HDT7737350.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKITAAIESVL"
     gene            complement(641..1099)
                     /locus_tag="RD508_002841"
     CDS             complement(641..1099)
                     /locus_tag="RD508_002841"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDT7737351.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1270..2415)
                     /locus_tag="RD508_002842"
     CDS             complement(1270..2415)
                     /locus_tag="RD508_002842"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HDT7737352.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPHHELHGVAKQQMSGFSGMISFTLKNEETAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2428..3345)
                     /locus_tag="RD508_002843"
     CDS             complement(2428..3345)
                     /locus_tag="RD508_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HDT7737353.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3773..4336
                     /gene="efp"
                     /locus_tag="RD508_002844"
     CDS             3773..4336
                     /gene="efp"
                     /locus_tag="RD508_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDT7737354.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4437..4607
                     /locus_tag="RD508_002845"
     CDS             4437..4607
                     /locus_tag="RD508_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737355.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEREETALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
BASE COUNT         1460 a          850 c          883 g         1497 t
ORIGIN      
        1 tttttattaa gttaaagaac ggattcaatt gcagcggtta ttttcaatgg agaagtttgt
       61 ggtgcaaatc gttcgattac tttgccattt ctatcaatca aaaatttagt aaaattccat
      121 tttattgctt tagtgacagt accaggagct tcatttttaa gataagtaaa aagaggatct
      181 gtattttctc catttacgtc aatcaattga tgcataggga aggtaacgcc ataagtggtt
      241 ttacaagctt ctgctgcttc agtcgctgaa tctagctctt gtttaaattg attggaagga
      301 aagcctaaga taaccagacc ttgtgtctga taagcttggt aaagttcttc taattgttta
      361 aattgaggtg ctagaccgca ttttgttgca gtgttaacaa tgattatcgg tttgcctgca
      421 tattttttca atgaatagac agtgccgtct tctaaagtag tttcaaaatt ataaatagac
      481 ataaagtttt ctcctttcta ttttatataa taaaaagagc gctaaactga aaactagcta
      541 tttgttttcc cgtttagaac tcttttcaga caataaatat ttaataaaat acgaagataa
      601 gatagctata ttgcttctca tctttacgtt cttttagaaa ctatgcttct acttcagacc
      661 attcatcgcg ttttgctaaa aattcacgag ccaaagcttg tgcaccttct agtgtatggc
      721 tggcagccca gccacattgt gtttcattgc ttgcaggtac ttcagtagct tcaagaacat
      781 ctttcattgt tgcttcaaga acatctaaaa tgtcttcgta gctttcatga ttcaatacag
      841 tcaagtaaaa gcctgtttgg catcccattg gagaccagtc tacgatgtaa tctgcgtgat
      901 tgcggattag ttcggcagtc aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt
      961 ctttatttgg ttgtttaaag cggacgtcgt atttaatgat gacatcgcca tgcgcacccg
     1021 tttttcgatc agctacacgt acataaggtg ctttgacttt tgtatggtca agattaaaac
     1081 tttcgacatt cattctcatt tgtaagactc ctatctgttt gttcattcgt tttgatgctt
     1141 ttcactaaag aattatttag tgaaatttac aaaaacgtct ttctacttga ttctaacact
     1201 tatcgtttcc aaggtgtagc aatctgaaat attttttaga tttttctgct aagtcgttta
     1261 ttgggacttc tagttcttga ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg
     1321 accatactca attcctacag aaagacggat caagccgtcc tttatgccag cctcttctcg
     1381 tttttctttt ggaatagacg catgagtcat gacagaagga atttccacta aactttctac
     1441 gccacctaaa ctttctgcta aagtaaatag ttggagtgat tcaacaaatg gaatagcagt
     1501 ttcttcattt tttaaagtaa aagaaatcat tccgctaaag ccgctcatct gctgcttagc
     1561 aactccatgg agttcatgat ggggtaatcc tggatagtag accttttcta ctgctggatg
     1621 agaaaataga aaatcagcta ccacaaaagc atttttttga tgttcctcca tacgaacact
     1681 tagtgtcttg attccgcgct gaagtaacca gctatcttgg ggaccaagta cggctccgat
     1741 agcattttgg taaaatccga tctgatcggc tagatcttta tggttagaag tcactaaacc
     1801 agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa cgatatcaga
     1861 accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag caataactat
     1921 caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct ttagaagcgg
     1981 attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt gttctatttt
     2041 atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa gaactttgtc
     2101 aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat cgccagcttg
     2161 aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga atcctcgaac
     2221 accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat taccagatct
     2281 cgaatattca tattgcttag gctggccgac gccatcttgc cgataagtgg atgtttgata
     2341 aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt ggatcaattt
     2401 tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata aatagcggtc
     2461 tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac gaatttctct
     2521 taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt gttctcgtgc
     2581 taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct gattgattga
     2641 aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt cgtgaggggc
     2701 tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc gaatgtcggg
     2761 atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc caattcctgc
     2821 tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta acgtatgata
     2881 gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt ttgatatctc
     2941 ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac taggagaatg
     3001 gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa acttctctgg
     3061 aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc caattcctgt
     3121 atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt gggcaaatcc
     3181 ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat ttaaatattc
     3241 tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt caaagcgata
     3301 aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatatggg cctcctaaaa
     3361 aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca tagagaaaaa
     3421 ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa ttaatagaca
     3481 tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat tgtttttggt
     3541 tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc atgaaaaaaa
     3601 ataaaagtca aaggattgaa agaaaaaaat atttcgatag catcgtttac ccgtgtttat
     3661 ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt ttctggccgg
     3721 ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa taatgatctc
     3781 agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga ttaaagttct
     3841 ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga aactgaaaga
     3901 tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat ttgaaaaagc
     3961 acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag ctttcttcat
     4021 ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag aagaaatgaa
     4081 atatatccta gaaaacatgg aagtaaaaat ccaattcttc ggtagcgaag tcatcggcgt
     4141 tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc
     4201 aacagtcact ggttcaggta aaccagcgac aatggaaact ggcttagtag tcaatgttcc
     4261 tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt cttatgtaaa
     4321 acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga gcttgacctc
     4381 ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc agcaaattga
     4441 aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa aagctagaga
     4501 gagaagaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
     4561 gaactattcc gaactatatt gaagcgaaaa tattttttca tcactaaata gtgttgaatt
     4621 tatgtttttg tgtataaata gcttctaata gttcgggtat tttgttttta taaccatttt
     4681 tattcttatt
//
LOCUS       DAPBCF010000117         4635 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.122, whole genome shotgun sequence.
ACCESSION   DAPBCF010000117 DAPBCF010000000
VERSION     DAPBCF010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.122"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..1614)
                     /locus_tag="RD508_002846"
     CDS             complement(<1..1614)
                     /locus_tag="RD508_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDT7737356.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYSGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFK"
     gene            complement(1777..2370)
                     /locus_tag="RD508_002847"
     CDS             complement(1777..2370)
                     /locus_tag="RD508_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737357.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLVTKE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            complement(2371..2703)
                     /locus_tag="RD508_002848"
     CDS             complement(2371..2703)
                     /locus_tag="RD508_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737358.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            complement(2755..>4635)
                     /locus_tag="RD508_002849"
     CDS             complement(2755..>4635)
                     /locus_tag="RD508_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737359.1"
                     /translation="GSPAFQIIQNNVIDVSTLLENDPNKVEHIPTDKRNALTAKNFKT
                     ANINGIITPDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYV
                     YTSGYRRYISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETG
                     QRMKSAIEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIA
                     LFKGSQSVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSNLND
                     IRKNGFGNRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNE
                     RGLKGTAEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDA
                     YGEGQVNAAVKANTTTEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPK
                     TDPEQYRYKSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSTKVGLP
                     KAENLPTKDSRLNQFKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLSESGETE
                     NASVQSIVTREAAPKPIQNVHTGYKPANVAFTAPTKINVTRETKNRNNELKEQLLKDI
                     KS"
BASE COUNT         1226 a          968 c          759 g         1682 t
ORIGIN      
        1 tttgaagtct tgttcttcca tttgtttttc tttaattaaa cgtcgttgtc ttcttccttg
       61 aatcaatgcc tgattccaaa tcaacgtcat agccatgtac atttgacatt gttgtacccc
      121 tcgatctaag cctgtaatag agtcaatgtc aaaaaagacc aactgttgtt ggtcaaggtg
      181 tcgaatcgta ctatgaccat caaaaatcat gccatacgtc tcacataagg attctacgat
      241 ggattccatt tcttcttttc gattcttttt ctcttgggaa gcacctggta attccagttg
      301 tcctaaaaag tctaaaaatt ctttgaacgt cggataagct tctggatctt tacctgtgac
      361 ttgcgtctca gtatttgaac gcgaatttga ggaagtaaag ccgcgtggta ctgttccata
      421 ctcttcataa aaacgattta agtaggtctt aaattctgct ttcatcgttc cttttagctg
      481 aggactcact aactgtacct gatagaccac tttgtctaag tgcgtttgat aggacgctgc
      541 ttcattgatc ttcaaatctt tgactgatcc atcgtcatat aaactggatg cttcatcata
      601 cgtccgtgtg gcaaatatct ctaaaggatt gatcattccg tcagatccgt ctaaacgcac
      661 cataataccg ctatattcct ttaagaaagg aataaagtct tttccctttt caaagcccca
      721 aataaagtct cctgcagcta aatgggcttc cgcgatcatt ttaagaacgg tcgatttacc
      781 agctcccatc attcctagaa gcaaggtatt agtagacaac cgtacactat ttttatacgt
      841 cgcattccag acaaatgggc cgcctgtcat ggtttcccca tattgtgtac ctcctggatc
      901 ttttagcgtt tggtggtgga acgggaaacc tccgccaatg tttaacgatg gtagtgattg
      961 ccctttgata tttccgaacc attcagcttg ttcatcgaac atggtaaaca tcgattgcca
     1021 atctcgtttg gttttatgca gataagtcac cgcacgataa tccattcctt tgagattttc
     1081 gatcagttcc tgcgctcgtt catctacttc ttgaatcgtg tttccgtaaa catgtactct
     1141 cactttgact tgtttagaaa tttccccatt agaagtcaat tttcgggcat attccgctag
     1201 ttccaggtat tcttccgcac ttttatttcg gtcagtcgct tttcgttcat tatctgatcg
     1261 atcatttaat tcatctaatg cacggttgat ttgatcaatc actttttgct tttcatctgt
     1321 gctaacatct agtgtggcca ctgtatgagg attgttcatg agattggcca accaaaaaag
     1381 agtaggattt tttgtgtagt gatagactgt cacacatcgt gaataaccat ttccataggt
     1441 cacatactct tcatcgaaat ttaatccacc ttgtggcatc acttgtttta aaaaatctaa
     1501 atcataccct ttggatttta aaatttctat ttcccgattt cctagttgct ttaatggatc
     1561 aagtactttt tgatcatttt gtggtgaaaa agctgtttta atcgcttcta acatgtacag
     1621 tcacctcttc ttgtttgatt ctttacttgg ttaaaagatt gcccttttcc caacttaccc
     1681 aggcttaaag tgtgaggaaa ttttctagtg atctcttcct tcggaacatc attttctaac
     1741 catatcaacg gatatttcat tctctcttct ccattcctac tcatcattca tattgttcat
     1801 tcgataaaga atcttgatca attctttttt gtagagtggt tttaacccta aaatgccact
     1861 agatcgcatt aactgacgat ttctggtttg taaatccttg attgtctttc cttcaatgac
     1921 gaaaaagaag cttaagtcag gacgttcttg ttctgctcgt ttcaattcct ggatttcctc
     1981 tactaatttc ttttcatatt ttcttaatcg ctgtagattt cttcctaagg attgttccat
     2041 acgattctta tctaataatt gccgcttttg cacgatttgt tccgttagat ccgtctctgt
     2101 ggtcaaacta actaacttaa ttgttggcac atacgtacgc atgacggtgg tcaactgatt
     2161 cattcgttct agtttctctt gttcgtttaa tccttccacg tctgtagaaa ctacacgata
     2221 ataacgttga aaatgatctt ctttagtaac taagactccc tcttctgtac aggatttata
     2281 aggaaataaa tccaagatag atcgttcttc tggttttcca aactgcaaaa tggatttctt
     2341 atcaactgaa ttttgtcctt tgactcgcat ttattcatcc tccttatacg taccatgata
     2401 atttcggtta ggatctaacg catgatagtg gttcttatcc gtaaagaaaa tagattcgat
     2461 aatcgcaaaa atttgtcgtt gacctgggtt attatagggt cgccaaacaa tcactagagc
     2521 tatcgcaatc cataagccat aattcaagag tgcaaaaaag agtggtaagt ggacaagatt
     2581 attgactatt ttcgcccaaa aaaagcaacc accaagcgtt aatagatcta aaaagaaaaa
     2641 ggcgaaaaac ttccattccc cactaaatct tggaggattt ttcatgttaa tatatttatc
     2701 cataaatgat ttctcctttt catacataga aaaaaggcct aactcgtagg ccttttatga
     2761 tttgatatcc ttcaataatt gttctttcaa ttcattgttc ctgtttttag tttctcttgt
     2821 tacatttatt tttgttggtg cagtaaatgc cacatttgct ggcttgtaac ctgtatgaac
     2881 gttttgaata ggttttggtg cagcttctct tgtcacaata ctttgaacgg acgcattctc
     2941 tgtctcccca ctttcagata aattgtaaga aacagttgtc aaattcccat tttcaggcaa
     3001 acgacttgat ttcatttgaa cagtacctgc aggtgattga tgaacaaagc tttgatcatt
     3061 ctctttgaat tgattcaaac gactatcttt cgttggtaag ttttctgcct taggcaaacc
     3121 aactttcgtt gatttttcag ttccaacttc gattccatta tcatttggta gatcgatgga
     3181 atcctcatcc gtttgtactt cttgatttcg ttttggtaaa tctgaaatgc gtttttcgtt
     3241 ttcagaatta atgttagatt tataacgata ttgttctgga tcggtttttg gtaactgacc
     3301 atgttgtcct tcttctgaat ctttttctcc gatcgaattt tcgttagaat gtaactcatc
     3361 ttggtgatct ttggctgaag gaatcgctgc accttcttga ttttcttttt cggttgttgt
     3421 attagctttt actgctgcat tgacttgtcc ttcaccatac gcatctttta gtccttcttt
     3481 gacttctgaa gctttttctt tttgtttttc tagtgcttcg gatggattct tcacagcttc
     3541 agccaattct ttagctctcg tgccgtctaa tttctcttct aaggtgtctt tggctttttc
     3601 tgtaagatct tcagctgttc cttttaaccc acgttcattg acgtaaccaa gaccttctgc
     3661 ggctttagaa acaccatttt tcgctttccc gaacatttcg gaaactgttt tcttactatt
     3721 aggtacagtt gtagctttat cgtctgattg ttcttccccg ttatcagggg taacatcttt
     3781 tcgattgcca aatccatttt tacgaatatc atttaaattg cttaaaccac tcttaccagc
     3841 acttgcaagg tttttagccc cactacccac atttttcgca atatttccta aggcaaacat
     3901 gctaagaaga gaattgctgc cgtttttcag actcgtatca acgccgaaaa ttttcgtaac
     3961 tgattgagag cctttgaata gcgcaatggt taatacaatt aaagcgacaa catacaagaa
     4021 tccattgatc tttcctgccg catgcaaatc accgatacct gaaagcatta atgtatagat
     4081 tcgtaattct aaaatcgtaa atgccaataa caagaaggat tgagaaatat cttctatagc
     4141 acttttcatc cgttgtcctg tctcaaagtc cgttgacgcg gcaatcacta aatagaattt
     4201 tttaaatacc agctcaataa tgcaagtaac aatcgtaaac aagataaata aataggctac
     4261 cgacaaagaa gattcaccag ctaaaataat acctggacta ctaatgtatc ggcgatagcc
     4321 tgaagtatac acatattttg ctaaaccttc atcactaatt tgaacaggga tttctttccc
     4381 attatcgtct aactctagtc gatactgtaa tgcctttaac cgatcttttt gtactgtact
     4441 aatatcactt gattcagaca ttttcttagc ttgatcaggt gtaataatcc cattgatatt
     4501 cgctgtttta aaatttttcg ccgtgagagc atttcttttg tctgttggta tgtgttctac
     4561 tttgttcgga tcattttcta gtaacgtact cacatcaatc acattatttt gaataatttg
     4621 aaaagcaggt gaacc
//
LOCUS       DAPBCF010000118         4524 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.123, whole genome shotgun sequence.
ACCESSION   DAPBCF010000118 DAPBCF010000000
VERSION     DAPBCF010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4524
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.123"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(561..1601)
                     /locus_tag="RD508_002850"
     CDS             complement(561..1601)
                     /locus_tag="RD508_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDT7737360.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1950..2276)
                     /locus_tag="RD508_002851"
     CDS             complement(1950..2276)
                     /locus_tag="RD508_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737361.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2263..3066)
                     /locus_tag="RD508_002852"
     CDS             complement(2263..3066)
                     /locus_tag="RD508_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDT7737362.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3419..3709)
                     /locus_tag="RD508_002853"
     CDS             complement(3419..3709)
                     /locus_tag="RD508_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HDT7737363.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3845..4024)
                     /locus_tag="RD508_002854"
     CDS             complement(3845..4024)
                     /locus_tag="RD508_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737364.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4021..4371)
                     /locus_tag="RD508_002855"
     CDS             complement(4021..4371)
                     /locus_tag="RD508_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737365.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4364..>4524)
                     /locus_tag="RD508_002856"
     CDS             complement(4364..>4524)
                     /locus_tag="RD508_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
                     /protein_id="HDT7737366.1"
                     /translation="EENLDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAG
                     GNGGIKND"
BASE COUNT         1372 a          786 c          636 g         1730 t
ORIGIN      
        1 tccgttgcgg gtaataccgt aacactgaag ggcacgcatt aaggcgtcat cttaatgctt
       61 tcctgtagga cactgacgga gattaccagt ctcccgagcc ttacaggggc ctttcttttt
      121 tttgtatttt caattatcac aatttatcgt ccaaaagtgc agaacgaaaa tcaattcatc
      181 acaagcatat cagacaatta aatttaaaac aactaaaaat atacaaaaaa gtgtaattga
      241 atattagcag cactgcctga aaagaagtaa tatcaggctt ttcagcttgg ggaaataagt
      301 gaattacctc tcttcatgaa ttattataac tcaaaaaagc acatatgcaa acactagttc
      361 cctatttttt tgaatgaaaa ataactaaaa tatctaacga ttatgacttt aaaacctacg
      421 tttgtgattg ttttcataaa cttttaatct aaaaactccg gaataatagc tatttatttg
      481 taacatttgt aataaaatta aaatcataaa aaagttctaa tttaaaattg atcattttta
      541 tagtgatcgc tttttatcaa ctactctagc caattttccg tactaactgt tggtaattcg
      601 ttaaatgttt ctctttgttc gtttgcaagc tttgccgcaa tagctttttc gacaaaccaa
      661 ttttttacat aaacgaaaat tagattctgc aaattgttta ctttttcagt tttttgtttt
      721 tgataagctt tcagcaaagt catatataat cctttgtcag catcaattcc ataagattcc
      781 agttcttcat aaacaacaac tgtttgctct aattcttcag cttttttctt tgcattatga
      841 atagtttgga cggttttttg agcgtcttcg taagtactag aaaatgtttt tatcaagttt
      901 aatacatttt ctggtacaaa tgtatttata ctgtcctctt tcatgatgtc gacgaagtta
      961 tctagtaaaa cttgattttg taactgatca gtttcagtgt ctattatgtg tctattagtg
     1021 tctatagaat tagaatagaa tagattgtct gcgattttcg caattacggt tgagtccttg
     1081 atatgactgg attttgccgt atttgcgatt ttcgcaatta cggtggtatc attgatttct
     1141 cgcggttttg ccgtatttgc gattttcgca attacggtgg tatcagtatt gtcttcctct
     1201 tccatgattt taaagacgtc ttgattcgtt acttctggct tgcctaagta caataaatta
     1261 ggcatggatt caatcttacc gtcacgttta tttactcttc ctctcttctg tttcagaaga
     1321 cctgcttttt ctaattcctt tttgatttta gatactttac cttcgcggca ttgtaacaat
     1381 ttcattaatt cttcaactgt gaatatgaaa aatatattat catcagaatc tacccagtta
     1441 tttttgactg aataatcaaa tcgatcttta agtagcatat aagcaatttt tgcatcattt
     1501 gatagatcca tgtatttttc gttagtaaaa aataccttag gcatttgata atatttttca
     1561 cgataaattt cttttgattt gtaataatta aaatcattca tagccaatcc tctttctgta
     1621 ggatagcgtt ttgttcaaaa ctatgttaca atgaattaaa caaatatatc tatccactat
     1681 atatttttct actgctgata agtcgccaaa ctttgttaaa gcagtagtct ttttttatct
     1741 ttttttagtt taccttaaaa aataaattaa agcaaaccgc tctatttcaa ggtttaagct
     1801 catagtaact atatcacgat attacaataa tattatatca cgatatcgta atattacaat
     1861 atgaagataa gcgacttatc agctttgata ctactgattt ttataaaaaa aatatcacga
     1921 tattatgata tcgtgatatt gaatgtaaat taaattttat tttgtttctt tgctagttta
     1981 tatccttcaa tcaagtattc ttcaggtatg gactttaata gcgcatcttc tataacgtct
     2041 ggtttacttt tgtctgattc agcaatagtc gtccaatatt tgagtgctga cattagaatt
     2101 ggatttatac gaatgctatc tgctgttctt acactacttc cttgatcttt tatgacttta
     2161 cttatatttt tcttggttaa ttcgatttct tctacttctt ttgatttaaa attcttttta
     2221 tttttatttc ctagtaatct acttactgca gcttgactgc gattatcttc tgccatcaaa
     2281 atcaccaact tcttttaaat attcttctgt aaatgcttta tagtcatctt cagctgttga
     2341 gggtttatta aaattgatta gatctgatcc agcagcttgc gcttcgtcaa cggttattgt
     2401 cctacgaata taagttttga aaatttttgc accaatgact ctagaaattt cggttgctgc
     2461 agacgtcatt tctttagaaa tgttataacg cttattatac ttagtaaata gaactcctcg
     2521 tacttcaagc ttgtcgttcg tatattcttt taccgtttca atagtttcac ttaactttat
     2581 tagtcctttt aatgagaaat acgcagcttc aactggaatg ataatttcat cagaaacagt
     2641 aaatgcgttg actgtaagca ttcctaaact tggtggacaa tcaattataa tataatcata
     2701 gttgtccttg attggttgaa gtactctttt aagcctgtgt tcacttccta cttgagtaaa
     2761 ttccctctct gcagaagaaa gggctatgtc ggctggcaaa acatcaattc ctttatagtc
     2821 cagaatagca tctgtaatgt cagcctcccc ttttaatact tcataaattg taggttggtt
     2881 tgttccatct atatcgaaac ctacattatc tgtagcattt ccctgaggat caatgtccac
     2941 taaaagtaca tttttaccgt aaacaaattt caaacatgct gctaaattaa cgctagtcgt
     3001 agttttagaa actccacctt tttgattggc tactgacaat attcttgcca ttaaaatatc
     3061 ccccattcat cttatattat aatataatta tatcataata ttgtgatatt gcaatatcgt
     3121 atatgcatta tattgtaata ttgtgtgatt attttgtttt aaagatatat atcggttcgg
     3181 atataaagat tattcatatg ttattcgaaa ttaaaataat cactttttat tactttaaaa
     3241 ttttttatta atgataagaa atatgttttg cgagcagcaa ctagaataat ttaaacatta
     3301 ctaaactgtc tatattgtta ctaataattc ccttcttata gtgcattttc ttagaaaaaa
     3361 acaatattac gatatcatga tattaagata tcgtaatatt atacaattgt gattgatatt
     3421 atatatgttt ttttattttt ttatcatgtt taatcttgaa ggaatcatat tctttttcta
     3481 aagacaggag cttttcataa acatcagaca tgtttaaact agaggccagg cttaaatcat
     3541 aaacgaatga agcaggtaat gattttattc tacgttgtcg ggttatccag cttgcaaccg
     3601 ttccttgtgg gtaggcatat aactcacaaa attgttctac agtgattcct aaattcttga
     3661 taatgtaaac attgatcggg tgcgagtaaa caaatgtatt gatagacatg gtgcgtaagc
     3721 ctactttctt ttattattgc gtttgcaata atagtttaac acacgcatta ttctagtatc
     3781 tactcctatt tgtaaaaaca aaaaaggatt catagagata actctataga atccgtaaaa
     3841 taccttatat atataacggg aagatataaa acctaaaatt atgataacct gctgcagctt
     3901 ctacatagaa agagaagcgc tcaacaccaa cctcatttat caaacgttgg ccataacccc
     3961 aaatctcttc tgatagctga tcaaaggtta tatactttag ctcatattgc tggataatgt
     4021 tcattctaat cgactccatt tattatcctg gtaaaattcg atatgacgta tttcgtcgta
     4081 gtgaattttg tcttttccaa cgtagatccc cagctcatca ctacctaaga tcttgccaat
     4141 gatatcttct ggatagtatc cttcagcgtt tcgttcttct ttttgaatag atactgatct
     4201 attttttatg actgcagcgt tcaatacttc cgcaatctct tcagtcgtca tttgttcttt
     4261 tgctaaattt tgactggttc gttgttcatt gtcggcatca atttcttcag tatgatcaga
     4321 taaataaaac cctgcccact ttaaacgtcc acgatcattg taatcaatca tttttaattc
     4381 ccccatttcc gcccgcatga ccaccaacaa gtgtgcttct agtaatgctt ctagcgcctt
     4441 ctaacattga agaagcatgt acaatcgacg taaaaccata tttttgccga atcttgtcaa
     4501 taattttatc taaattttct tcgt
//
LOCUS       DAPBCF010000119         4467 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.124, whole genome shotgun sequence.
ACCESSION   DAPBCF010000119 DAPBCF010000000
VERSION     DAPBCF010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.124"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(25..570)
                     /locus_tag="RD508_002857"
     CDS             complement(25..570)
                     /locus_tag="RD508_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin ECF transporter"
                     /protein_id="HDT7737367.1"
                     /translation="MLPTSNSRFPIRRITTLALFSAACIVGRILFTWIPNVQPMTAIL
                     LLLAFYGSYTDALIVTLVSLLGTNLYLGMGSWTISQLIAFSSIVTVFHFLSNCALIKH
                     HISIQAIIAFLCGLLYGLIVSRVEVFIYQLPSFWAYYFQGLFFDILHGTGNLIFYLVL
                     VSVFKRILLPAINSSKNKLNS"
     gene            720..3203
                     /locus_tag="RD508_002858"
     CDS             720..3203
                     /locus_tag="RD508_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12-dependent ribonucleotide reductase"
                     /protein_id="HDT7737368.1"
                     /translation="MDYPKKYIEKLNQDISSYKEVAKITAEMTQTFDGISRLIMLDRY
                     AFKDMSGKTLTVGDLVILTTHADPQYPARGIGKIEEINKEQLIIRIEEEFQSSLTDPE
                     EIASGRVIRNINEVEKPLELYFEQIAARVARGISDIEGEKKAQFFTEFYQHLTEQNLI
                     PAGRVLYGAGTNSEVTYFNCYVMPFIHDSRGGLAKHRQEVMEIMSRGGGVGTNGSTLR
                     PKSAIVHGVNGKSSGSVSWLNDLANLTNLVEQGGSRRGAQMIMLNDWHPDIFEFIISK
                     IQNPAILQNLIHTSQSPTVRQLASEKLTFEPLTANEKEWLEFLVDHPTNDMEDKFLKT
                     AQQKLKAGGTYSVKDPDFLTGANISVCLTKEFMEAVETDQTYELRFPAIEDYDASEMA
                     DYDQHWMEVGDVREWAETGRKVKIHQTIKARELWDLITYCATYSAEPGIFFIDNANEM
                     TNAQAYGQKVVATNPCGEQPLTPYAVCNLAAINLANMVDKKTKVVDFEKLTDVVRASV
                     RFQDNVIDATPYFFKKNEQQAKGERRVGLGVMGLADLLIYCEKVYGSEDGNRLVDQVF
                     EKIAITAYQTSVELAKEKGSFPFLVGKTVEETTALRQRFIESGYMKKMPESIRQAILK
                     YGIRNSHLLTVAPTGSTGTMAGVSTGLEPYFSFSYFRSGRLGKFIEVNAEIVSEYLEK
                     NPEKTADNLPPFFVTAMELSPKDHVSVQCTIQRWVDSSISKTVNAPKGYQVKQVAAIY
                     EDLYQGGAKGGTVYVDGSRDSQVLTLEADGNVFEEPVVGVADNQITLDSLESSEAEEI
                     CPICHEGRIEEIGGCSTCTNCKVQLKCGL"
     gene            3217..3780
                     /locus_tag="RD508_002859"
     CDS             3217..3780
                     /locus_tag="RD508_002859"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HDT7737369.1"
                     /translation="MKIYTKSGDKGNTSIIGGERIKKSDARVCAYGSVDEVNSWVGKI
                     ISELDDKKFELLKKELVVLQILLFDIGTDLATPIGIKEMIVGKEEVTKIETLIDFYQA
                     KVPVIEKFILPGGHPVACDMQITRTVIRRAEREITRLIVSDEPINLHAYKIMNRLSDL
                     FFVLARYVNHVYATKEPFYERAGKVFH"
     gene            3796..4200
                     /locus_tag="RD508_002860"
     CDS             3796..4200
                     /locus_tag="RD508_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HDT7737370.1"
                     /translation="MKKLATLLTVFIGLFIMTGCQSNQNDQASSKASTQATSEVAKSS
                     ALIKLTDSDKEITSKTVTYKSGESLLVILKANFEVKERDGFITSIDGHAQDESQNKYW
                     TFTINGKMGEKGAGETTLDNDDQVVFNLGVFK"
     gene            4402..>4467
                     /locus_tag="RD508_002861"
     CDS             4402..>4467
                     /locus_tag="RD508_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7737371.1"
                     /translation="MSNFKGKQFEKDIIMVAVCYYL"
BASE COUNT         1561 a          691 c          941 g         1274 t
ORIGIN      
        1 agatattgtg atttagatac tcatctaact atttaattta tttttcgaac tattaatagc
       61 aggtaataaa attcgtttaa acacagaaac taatacaaga taaaagatta aattacccgt
      121 tccatggagg atatcaaaaa ataatccttg aaaataatag gcccaaaaag aaggtagttg
      181 atatataaag acttcaactc tcgatacgat caatccgtaa agaaggccac ataaaaatgc
      241 aatgattgct tggatagaga tgtgatgctt aatcagggca cagttagata aaaaatgaaa
      301 aaccgtaacg atactactga aggcgatcag ttggctgatt gtccaactac ccattcctaa
      361 ataaaggttc gtgcctaata agcttactaa agtaacgatt aaagcatctg tataacttcc
      421 ataaaaagcg agtaaaagta gaatggctgt cattggttgt acattcggta tccaagtaaa
      481 aaggattcta ccaacaatac aggcggcact aaataaagcg agggtggtaa tccttctgat
      541 tggaaagcgt gaattagagg ttggtaacac taggaaaact cccttgtttt aattgataat
      601 agttctcatt gtatcagaat aaaaattaat tacaagattg aattacactt tatatagggc
      661 tataatcatt ggcaggcaca atatgttgtg tttgttaatg gtaaaggtgg tattatttaa
      721 tggattatcc taaaaaatat atagaaaaat taaatcaaga tatctcttct tataaagaag
      781 tcgctaagat aactgcagaa atgactcaaa catttgatgg gatttcaaga ttaatcatgc
      841 ttgatcgcta tgcatttaaa gatatgagcg gaaaaacttt gacagtcgga gatttggtta
      901 ttttaacaac ccatgctgat ccacaatatc cagcaagagg gatcggaaaa attgaagaaa
      961 tcaataagga acagttgata attcgaattg aggaagaatt tcaaagctcg ttaactgatc
     1021 cagaagaaat tgcttcagga cgagtgattc gaaatataaa tgaggttgag aaaccgcttg
     1081 aactttattt tgaacaaatt gcagctcgtg ttgctagagg aatctctgat attgaaggag
     1141 aaaaaaaagc tcagtttttt accgagtttt atcagcattt gacagagcaa aatctcattc
     1201 ctgctggtcg tgtactttat ggtgcaggaa cgaattcaga agtaacatac tttaattgct
     1261 acgttatgcc attcatccat gactctcgtg ggggcctagc aaaacatcgt caagaagtga
     1321 tggagattat gagtcgcggt ggcggtgtag gaacgaacgg ttcaacgcta cggccaaaat
     1381 cggcgatcgt ccatggggtg aatgggaaat catcaggttc agtttcgtgg ctcaatgact
     1441 tagctaattt gacgaattta gttgaacaag gcgggagtcg tcggggagca caaatgatca
     1501 tgttgaatga ttggcatcca gatatttttg aattcattat ctctaagatt cagaatccgg
     1561 ccattttaca aaatttgatc cacactagcc aaagtccgac agtgcgccaa ttagctagtg
     1621 aaaaactgac ttttgaacca ctgacagcaa atgaaaaaga atggttagaa tttttggttg
     1681 atcatccgac aaatgatatg gaggataaat ttttaaaaac ggctcaacag aaattaaaag
     1741 cgggtggtac gtacagtgtg aaagaccctg atttcttgac cggagccaat atctccgtct
     1801 gtttaacaaa agaatttatg gaagctgtcg aaaccgacca aacttatgag ttacgctttc
     1861 cagcaatcga agactatgac gctagtgaaa tggctgatta tgatcaacat tggatggaag
     1921 ttggagatgt cagagaatgg gctgaaacag ggcgtaaagt aaaaatacat caaacgatca
     1981 aggctcgcga attgtgggat ttgattactt attgtgcaac gtattcagca gaaccgggaa
     2041 tattttttat cgataatgct aatgagatga ccaatgctca agcctacgga caaaaggtag
     2101 ttgcaaccaa tccatgtggg gaacagccat tgacgcctta tgcggtatgc aatctagcag
     2161 caattaattt agccaatatg gttgataaaa aaacgaaagt tgtcgacttt gaaaaattaa
     2221 ctgatgtcgt aagagctagt gttcgttttc aggacaatgt aattgatgcg acgccttatt
     2281 tttttaaaaa aaatgagcag caagctaaag gtgaacgacg cgttggactt ggggtcatgg
     2341 gattggcaga tttattgatt tattgtgaaa aagtctatgg atctgaagat ggaaaccgtt
     2401 tagtagatca agtatttgaa aaaattgcta ttacggctta tcaaacgtcc gtcgaactag
     2461 caaaagaaaa aggaagcttc ccatttttag taggcaaaac agtcgaggaa acaaccgcgc
     2521 ttcgtcaacg ttttattgaa tcgggttata tgaagaagat gccggaatca atccgacaag
     2581 cgattctaaa atacggtatt cgtaattctc atttactaac agtcgcacca acagggtcaa
     2641 cgggtactat ggctggtgtt tcaaccggac tagaaccata tttctctttt tcttatttta
     2701 gaagtggtcg cttaggaaaa ttcattgaag ttaacgctga aatagtcagt gaatatttag
     2761 aaaaaaatcc agagaaaact gcggataatc taccaccatt ctttgtcact gccatggagc
     2821 tttcaccaaa agatcacgtg agtgttcaat gtacgatcca acgttgggta gatagctcta
     2881 tctcaaaaac agtcaatgca cctaagggtt atcaagtgaa acaagtagct gcgatctatg
     2941 aagatctgta tcaaggcggt gctaaaggtg gaactgtcta tgtggatggt agcagggatt
     3001 cgcaagtgtt gacacttgaa gcagatggca atgtatttga agaacctgta gtaggggtgg
     3061 cagataatca aattactctt gactcattag aatcatcaga agcagaagaa atatgtccga
     3121 tttgccatga gggtagaatt gaagaaattg gtggttgcag tacctgcact aactgtaaag
     3181 tacaactaaa atgtggcttg taaaaggagc tattcgatga aaatttatac taaaagcggc
     3241 gataaaggaa atactagtat tattggtgga gaaagaataa aaaaatctga cgctcgcgtt
     3301 tgtgcttacg gtagcgttga tgaagtaaat tcttgggtcg gtaaaattat ttcagagttg
     3361 gatgataaaa agtttgagct gttgaaaaaa gaactagttg tattacaaat tttacttttt
     3421 gatattggaa cagacttggc tacacccatc gggattaaag aaatgattgt agggaaagaa
     3481 gaagtaacta agattgaaac gctgattgat ttttatcaag caaaagttcc agtcattgaa
     3541 aaatttatct tacctggagg acatccggtg gcatgcgata tgcaaattac acgaacagtt
     3601 attcgtcggg cagaacgtga aatcacacga ttgattgttt cagatgaacc tatcaattta
     3661 catgcataca aaattatgaa tcgcttatca gatttatttt ttgtacttgc acgttatgta
     3721 aatcatgttt atgctaccaa agagccattt tatgaacgag cagggaaggt attccattaa
     3781 gagagggttt taaacttgaa aaaattagca acattattaa ccgtttttat cggactattc
     3841 attatgacag ggtgccaatc aaatcaaaat gatcaagcct cttcaaaagc atccactcaa
     3901 gcaacaagcg aggttgctaa atcaagcgcg ctgataaaat tgactgatag tgataaagag
     3961 atcacttcaa aaacagtcac ttacaaatca ggagaatcat tattggtaat tttaaaggct
     4021 aactttgaag taaaagaaag ggatggcttt attacttcaa ttgatggtca tgcgcaagat
     4081 gagagtcaaa ataaatactg gacattcact atcaatggaa aaatgggtga aaaaggcgca
     4141 ggtgaaacta cattagataa tgatgatcag gtagttttca atttgggtgt atttaaataa
     4201 aaattatcgt tctttacagc aattgagcga taattaagta agagaaaatt attagttttt
     4261 aaaggaatat gttaatttta aaacacgttc aaaccaatca tttcgaaggg gttgaacgtg
     4321 ttttttggtt ctgttgcaaa gttttatcta aatacctatt tagtgtaaaa tagctgaaac
     4381 taaaacataa ggagaattac catgtccaat tttaaaggta aacaatttga aaaggatatt
     4441 atcatggtag ccgtatgcta ctattta
//
LOCUS       DAPBCF010000120         4461 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.125, whole genome shotgun sequence.
ACCESSION   DAPBCF010000120 DAPBCF010000000
VERSION     DAPBCF010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.125"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            232..549
                     /locus_tag="RD508_002862"
     CDS             232..549
                     /locus_tag="RD508_002862"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737372.1"
                     /translation="MVFEDQYLQIKNSENIEACIEISNSQESNIFVSPENGPVKPNFN
                     YLTYDRFSQNTVFDGYKLEQSSPAIHSGKKVIDKNGYNLGTDFFGIKLDGILDIGAVK
                     SSK"
     gene            571..1383
                     /locus_tag="RD508_002863"
     CDS             571..1383
                     /locus_tag="RD508_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7737373.1"
                     /translation="MNDISFFQIFSLICLAILGGIDPYLSGLQLSKPAISGFLAGIIM
                     GDINTGLLVGATLQLMVLGVGTFGGSSIPDFGTGAIIGTALGVVSGKGIEFAIGISVP
                     VGLLLVQLDILARFCGVYFLHRVDKHIEEENFHKISLEAWLSLVPIALSRAIPVGLCL
                     IFGNEVVNTVLNYAPDWLMGGLKLAGAILPVVGIAILLHYLPIRNFFGFLIIGYILAA
                     YLNIPMMGISFAGLAAAIIHYKKLQDKRLLESKLDTINHIEVVNGEVDDDEI"
     gene            1370..2185
                     /locus_tag="RD508_002864"
     CDS             1370..2185
                     /locus_tag="RD508_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7737374.1"
                     /translation="MMKSNVSKLSSKDLRKVSLRYMFGAQLGWNYERMMNVAYVRAVY
                     PALKKLYKDEKELKSVLQSEMQFYNTSPFLSAFIIGIDLALQVEDGSKSKDAVAAIKT
                     SMMGPFAAVGDSLFGAVIPTIFGSLAAYMGLEGNPLGVLLWLLVSLIILFLRYFELPI
                     AFREGKKLVSSVGGLLKDLTESATLLGVVVIGGLVPSVVKVGVPFKLVIGDKKLSFQT
                     EMLDPIMPAIVPVVLVLLAYWLLSKKSLNSTKVIWIFLVLSILMYSLNILAVL"
     gene            2504..3961
                     /locus_tag="RD508_002865"
     CDS             2504..3961
                     /locus_tag="RD508_002865"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HDT7737375.1"
                     /translation="MKKNQPNVVLIVVDQMRADALSLNSQDKIISTPTLDMMASQGYN
                     FENCYSPVPSCVPARAALLTGLDQETSGRVGYEDEVPWNFKNTLPEVFKEQGYQTECI
                     GKMHVYPSRKRLGFDHVLLHDGYLHVDRKYDKSYGEQFEYSSDYLMFLKESLGSDADL
                     IDDGLNCNSWEARPWMYPEKFHPTNWVVSEGINFLRRKDPTVPFFLKLSFEKPHAPLN
                     PPKYYFDMYMDRLPDTLDLHIGNWEKLEHVVPDVCALRGKLKEDDQRRMLAGYYGLIS
                     HIDHQINRFLMALKEFRHDKDTIIWFISDHGDQLGEHYLFRKGYPYQGSIRIPSFIYD
                     PGDLISAKKHGIKELVKIQDIFPSLVDLVLGQYVNTDGKSVKQLLFGNCEGWRREIHG
                     EHSLGLDSSQYILTEKWKFIWFPVKNTYQLFDMINDPNEMKNLYYDKKYESIIYEMKH
                     KLVGYLKGREEGFVKNGQLIQIGISNIVSTLKSKK"
     gene            4152..4229
                     /locus_tag="RD508_002866"
                     /pseudo
     CDS             4152..4229
                     /locus_tag="RD508_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356150.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
BASE COUNT         1542 a          527 c          866 g         1526 t
ORIGIN      
        1 tataaaaaaa tccaaatata ttttattgca acttgctgtt tgatcagttt atctatgtta
       61 acaaaagtcg ctcatgctga aagtaacccc attggtaatt gttactatgt tagttcgcaa
      121 agagggagtg acactaattc aggattatct atatctgagt cttttaaaag tttaaataaa
      181 ataaatgaac ttaaataaaa tccaggggat aaagttttat tagaaaatgg attggttttt
      241 gaagatcagt atttacaaat aaaaaattca gaaaatatag aggcgtgtat tgaaatcagt
      301 aatagccaag agtcgaatat atttgtttct cctgaaaatg gtcccgtaaa acctaatttt
      361 aactatttga catatgatcg attcagtcag aatacagtgt ttgatggata taaattggaa
      421 caatcatctc ctgctattca tagtgggaag aaggttatcg ataaaaatgg ttataattta
      481 ggaactgatt tttttggtat taagttagat ggcatactag atattggggc agtgaaaagt
      541 tcaaaataat ataaaggagt tagtttgatc atgaatgata tttctttttt tcagatattt
      601 tctttaatat gtttagctat actaggaggt atagatcctt atctgtcagg attacaatta
      661 agtaaaccgg caatttctgg ttttctagca ggaattataa tgggagatat taatacaggc
      721 ttattagtag gagcaacatt acaactgatg gtcttaggtg taggaacatt tggtggctca
      781 tcaattcctg attttggcac aggggcaatc attggtacag cattaggtgt tgttagtgga
      841 aaaggaattg aatttgcaat aggtatttct gttcctgtag gcttattatt agttcaatta
      901 gatattttag ctcgtttttg tggggtttat tttttacatc gtgtggataa acatatagaa
      961 gaagaaaatt ttcataagat tagtttagaa gcatggttaa gtttagttcc tattgcatta
     1021 tctcgtgcaa taccagtagg tttatgttta atttttggta atgaagtagt aaatacagta
     1081 ttaaattatg caccggattg gttaatggga ggattaaaat tggcaggagc tatattacca
     1141 gttgttggga ttgccatttt actacattat ttgccaatta ggaatttttt cggtttttta
     1201 attattgggt atattttagc cgcttattta aatattccaa tgatgggtat ttcttttgca
     1261 ggattggcag ctgctattat tcactataaa aaattacaag ataaacgttt attagaatca
     1321 aaactagata ctatcaatca tatagaagta gttaacggag aggttgatga tgatgaaatc
     1381 taatgttagc aaattaagta gcaaagatct gagaaaagtt agtttaagat atatgtttgg
     1441 agctcaacta ggttggaact acgaacgaat gatgaatgtg gcatatgttc gagctgtata
     1501 tccagctttg aaaaagttat acaaagatga aaaagaatta aaaagtgtgt tgcaatcaga
     1561 aatgcaattc tataatacca gtcctttttt aagtgcattt attattggaa ttgatttagc
     1621 attgcaagta gaagatggaa gcaaatcgaa agatgctgtt gcagcaatta aaacgagtat
     1681 gatgggacct tttgcagctg taggcgattc tttatttggg gcagtgattc caacaatttt
     1741 tggatctcta gcagcttata tgggattaga aggaaatcca ttaggtgtac tactttggtt
     1801 attagtatct ctcattatac tatttttgag atattttgag ttaccaattg ctttccgaga
     1861 aggtaaaaaa ctggtatcca gtgtaggtgg attgttgaag gatttaactg aatcagcaac
     1921 tttacttggc gtagtagtaa taggaggctt ggttcctagt gttgtaaagg ttggtgttcc
     1981 attcaagtta gttattggtg ataagaaact atctttccaa acagaaatgt tagaccctat
     2041 tatgccagct atagtacctg ttgttttagt tttattggca tattggttat taagcaaaaa
     2101 atctctcaat tcaaccaaag ttatttggat atttttagtt ttgtcaatac taatgtattc
     2161 attaaatatt ttagcagttt tgtaatagat gtgggggcgt gatcaactaa tttatggcat
     2221 gtcccctgtt taattttcta aatattatat ttttaaatga atggaaagaa gatattagag
     2281 atttaatgaa taataagtta tatagataaa aaattaaaga tattttgata tcaaggttta
     2341 ttttagtata aagtattcgt gactaatcaa tcatacgcta taaagtttgg taatccattt
     2401 atatttcttg ttatcacaaa aaatatattc tttcaaaagg aaatatcaat ttcttaaatc
     2461 aagagagatt atttggatat tttgaatgat tggagttttt aatatgaaaa agaatcaacc
     2521 caatgttgtt ttaattgtag tagatcagat gagagcagat gcgttatctt tgaatagcca
     2581 agataaaatc attagtacgc ctacattaga tatgatggct agtcaaggat ataattttga
     2641 gaattgttat tcgcctgttc caagttgtgt tccagcaaga gcagcgttat taacaggatt
     2701 agatcaagaa acttcgggaa gagtgggtta tgaagatgag gttccatgga attttaaaaa
     2761 tactcttcca gaagttttta aagaacaggg atatcaaact gagtgtattg ggaaaatgca
     2821 tgtgtatcct tcaagaaaac ggttgggatt tgatcatgta ctattgcatg acgggtatct
     2881 tcatgttgat cgaaaatatg acaaatctta tggagagcag tttgaatatt ctagtgatta
     2941 cttaatgttt ctaaaagaat cattgggctc agatgcagat ttgattgatg atgggttaaa
     3001 ttgtaattca tgggaagcac gaccatggat gtatcctgaa aaatttcatc caacaaattg
     3061 ggtggtttca gaaggaataa actttttaag gcggaaagat cctacagtac catttttctt
     3121 aaaattatca tttgagaaac ctcatgctcc tttgaatcca ccaaaatatt attttgatat
     3181 gtatatggat agattaccag acactctaga tttgcatatt ggtaattggg agaaattaga
     3241 acatgttgtt ccagatgttt gtgccttaag aggaaaatta aaagaggatg atcaaagaag
     3301 aatgcttgct ggatactatg gccttatttc tcatatagat catcagatca atcgcttttt
     3361 aatggcttta aaagaattta gacatgataa agatacaatc atttggttca tttcagatca
     3421 tggagatcaa ttaggagaac attacttatt cagaaaaggg tatccttacc aagggagtat
     3481 tcgtatcccg tcgtttattt acgatcctgg tgatctgatc tcagcaaaaa aacatggaat
     3541 taaagagctt gtaaaaatac aggatatatt tccttcatta gttgatttag tattaggaca
     3601 atatgtaaat acagatggaa aaagtgttaa acagttgctc tttggaaact gtgaaggatg
     3661 gcggcgagaa attcatggag aacatagttt agggctggat tctagtcaat atatattaac
     3721 ggagaaatgg aaatttatat ggtttcccgt aaaaaatacg tatcaattat ttgatatgat
     3781 aaatgatcca aatgagatga aaaacctata ttatgataaa aaatacgaat ctattattta
     3841 tgaaatgaaa cataaattag taggatattt aaaaggtaga gaagaggggt ttgtcaaaaa
     3901 cggacagtta attcaaatag gaatttcaaa tatcgtttca actttaaaaa gtaaaaaata
     3961 aactaaaagt gaagatgcaa taaaaaatca acatagggta tactgagtca aaatatactc
     4021 agatacaggc aaaactttgc gtctttattt atttcaaaaa aatcaaatat tcggatggta
     4081 acaaacatac tactttgttt gggataaaat cagatctgag tcagagtaag ttcattctga
     4141 ttcagttttt tatgtctaac gacgataaaa gtttagcaca tacaagatgg aattgtaagt
     4201 atcccatagt ctttaccccg gagtatcgat gaaaagtgat ttatggaaaa ttaagagtaa
     4261 gtaactgttg gtgatagtat caccccaaat tagtatttcc agttttatga gctatttatt
     4321 aaatgattaa aaagagatga gggtgtgagc tgttactgat actttaaaaa aaacttttaa
     4381 agtactatca agtgattagc tcttctagag aggttaaaaa gaatttgttt tctagagtag
     4441 atattacttg agagtgtaaa a
//
LOCUS       DAPBCF010000121         4385 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.126, whole genome shotgun sequence.
ACCESSION   DAPBCF010000121 DAPBCF010000000
VERSION     DAPBCF010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.126"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(83..1051)
                     /locus_tag="RD508_002867"
     CDS             complement(83..1051)
                     /locus_tag="RD508_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDT7737376.1"
                     /translation="MSKKGTIINEWEKLTAPSNRRLNVQTLVQTIKLNWSIDRITIVG
                     KLNQNIFYHTQHDVLILDFEQLMRVNEGNGYLKAVGNNGWQLLDQHDENIAYIEISKW
                     QEGKGRIDFNPNKISRFLADSMKNFIHDLFLEPHFSRADVACDLIDVPDEFITQYRII
                     DPVSFKLIYGRSGKLETVYWGSRASERQIRLYNKKIEQEMKRKVVPSEINTWWRLEMQ
                     LRRGKATEWYAMVKESLDSFVSPHFLPTDIKPTDKVMIDGLLANHSNWAILSRNSKYK
                     YRNLLKRESQNDELTNHLRETFEESADDLKKELDTWLQGLDVTEEE"
     gene            complement(1500..2915)
                     /locus_tag="RD508_002868"
     CDS             complement(1500..2915)
                     /locus_tag="RD508_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HDT7737377.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDRQKTNDWHKHIDFTKSDEN
                     IYLEQTNLADKYEELFGEVVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     ILDDFQTNRADGSSTGISKQQAEQNRVIANKILVQYYKEFQERNPNLAVYNAVIHNDE
                     ISPHLHLNIVPVAEGYKRGVQKQPSFNKALVQQGIHADKDNGRVLFNNFRNQEVDSIE
                     RLMNDYGWKRDIVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSAEMRYISKQREK
                     NEREKALVASEKAKIEEEKKSIIDLEKELAVVFQKDPVPLTSFEKLPDGSYRLSSADF
                     VDLYQKASNATNSKKYADMANESLGNTLDKNIALFDKNMALEQENSFLKNQQKVDLSA
                     VVAENKKLKEENRSLRQRLTQLKNAFQKSITRLSIRFGLVEKDMGISEELKILDQEKT
                     LASQQNAPERNIGRSENEMEW"
     gene            complement(3137..3499)
                     /locus_tag="RD508_002869"
     CDS             complement(3137..3499)
                     /locus_tag="RD508_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737378.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKTVDNEWLADEKSAPSERDYPDESDDLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(3503..3841)
                     /locus_tag="RD508_002870"
     CDS             complement(3503..3841)
                     /locus_tag="RD508_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737379.1"
                     /translation="MVAILEVRCDMDKIDLREETVDRIELMYERLADYLNLPDEDNYS
                     EMLERIMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQI
                     SVINSKEKEM"
     gene            complement(3820..4239)
                     /locus_tag="RD508_002871"
     CDS             complement(3820..4239)
                     /locus_tag="RD508_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737380.1"
                     /translation="MTDLPEKMTIKNLADELGISKNTVRNQLVNAGYDLARYKDNGVI
                     MLDKELIGVVRSIYRSKGGQLTGDLPVNDAGNDFPLEKENEFLREQLAEKDRHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            complement(4232..4372)
                     /locus_tag="RD508_002872"
     CDS             complement(4232..4372)
                     /locus_tag="RD508_002872"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737381.1"
                     /translation="MSGKLLDVTQYELILKNNKIDSPIIIPKHAVKYVYGVAESNGED
                     ND"
BASE COUNT         1247 a          970 c          613 g         1555 t
ORIGIN      
        1 aaaaaaacaa cgacaacgtt atcacctgtt aaattcacca accaattttt cttaccaaaa
       61 tgcttttgtt tttctgccat tactattcct cctctgtcac atcaagtccc tgtaaccaag
      121 tatccaattc tttttttaaa tcatctgctg attcttcaaa tgtttctcgt aaatgattcg
      181 tcaactcatc attttgactt tctcgcttta ataaatttcg atatttatat ttcgagtttc
      241 ttgacaaaat cgcccaatta gaatgattag ctaacaatcc atcaatcata actttatccg
      301 taggttttat atcagttggt aaaaaatgtg gactcacaaa gctatccaaa ctttctttca
      361 ccatagcata ccattccgta gctttaccac gtcttaactg catttctaac cgccaccaag
      421 tattaatttc tgaaggcacc acctttcttt tcatttcttg ctctattttt ttattgtaca
      481 aacgaatttg ccgctcgctt gcccgactac cccaatacac cgtttccagt tttcctgagc
      541 gtccataaat taatttaaat gaaactggat caataattcg atattgcgtg ataaactcat
      601 caggcacatc aataagatcg caggcaacat ccgctcgtga aaaatggggc tctaaaaata
      661 aatcatgaat aaaatttttc atggaatccg ctaaaaatcg actgatttta ttaggattaa
      721 aatcaatccg cccttttcct tcttgccatt tagaaatttc aatataggca atattttcgt
      781 catgttggtc taatagctgc caaccattat ttccaaccgc ttttaaatag ccattgcctt
      841 catttacccg cataagctgt tcaaaatcta atattaatac atcatgttga gtatgataaa
      901 aaatattttg attcaacttt ccaacaatgg taattcggtc aatcgaccaa tttaatttta
      961 tagtttgtac caaagtttga acatttaacc gcctgttaga gggggctgtt aatttttccc
     1021 actcatttat gatcgtgcct tttttactca aatttagttc ctcctcaaag aaaaaagaga
     1081 ttggtggaaa gaattttcca gagttcacgt aactctaaaa aattcataac cagcaatctc
     1141 tagtcttgaa gaaacctgaa attattcgta taatgaattt gagttacgga gctagtgtga
     1201 ttagtttccg taaaggtcga gaacgtgtcc agcgttgctc gactttattt ttttgctctt
     1261 ttttcagttt atttatttga taactcaata atagcacttc tctttagcta tgcaaatatc
     1321 caaaaacata aaaccgcacc ctttgaaaag ggcgccccca aacttcgcta acgctaagtt
     1381 ggccaaaaaa tggacttgcc attttttagc aaatgtcagc ttcagggatt agtggtttag
     1441 ccgtcaactc cttatcctcg gcacagaccg cctccggtac cgttgactgc accgtataac
     1501 taccactcca tctcattctc agaacgccct atattacgtt ctggggcatt ctgctgacta
     1561 gccaacgttt tctcttgatc taatattttt agctcttcag atattcccat atctttttct
     1621 acaagcccaa aacgaattga taaacgagtg attgattttt gaaatgcgtt tttcagttga
     1681 gttaaccgct gacgcaaaga acgattttct tccttcagct ttttgttttc agcaacaacc
     1741 gctgacaaat caaccttttg ttgatttttc aaaaaagaat tttcttgttc taacgccatg
     1801 tttttatcaa ataaagcgat atttttatct aatgtatttc caagcgattc attcgccata
     1861 tcagcatatt ttttgctgtt cgtagcatta gacgcttttt gatacaaatc tacaaaatca
     1921 gcactagata agcgatacga gccatccggt aatttttcaa aactcgttaa aggaacaggg
     1981 tctttttgaa aaacaacagc cagctctttt tccaaatcga taatcgattt tttctcttct
     2041 tcaattttcg ccttctcaga agccaccaga gccttctcac gctcgttttt ttctctttgc
     2101 ttagaaatat acctcatttc cgcagaaacg ctctcacgct cttttacagc cgtttggcgc
     2161 aattcagaaa tttcactcat gatttctttg tattcgtgaa tatctttaat tttgttggta
     2221 ccgacaatat cccttttcca accgtaatca ttcattaatc gttctataga gtcaacttct
     2281 tgatttctaa aattattgaa aagcactcga ccattatctt tatcagcgtg tatcccttgt
     2341 tgaaccagtg ctttattaaa gctcggctgc ttttgaacac cccgtttata accttcagca
     2401 accggcacaa tattcaagtg caggtgcgga cttatttcgt cattatgaat aacagcatta
     2461 taaacagcca aattagggtt tctctcttga aactccttgt aatactgaac caaaatttta
     2521 ttggcaatca ctcgattttg ttcagcttgt tgtttcgata tgccagtaga agaaccatct
     2581 gctcgatttg tctggaaatc atctaaaatg cctatttgca caataaattc tcgttgaggt
     2641 tccaactttt tatccttgcg cactttcgct aaatagtcct cgatttttct atcggctctt
     2701 ttttgtttcg cattatattt ttctaccact tcgccaaaca attcctcata tttatctgct
     2761 agattcgtct gctctaaata aatattttca tccgatttcg tgaagtcaat gtgcttatgc
     2821 caatcattgg ttttctggcg atcagttaac tcacgattat tatgagaaat acttgtattc
     2881 ttcgttcctt ttttaaatga aatactaaac cccaagttaa aaccctcctt cgcgctgtcg
     2941 ctaataaaaa gattgtaaac ctttctgtta ctctttgtca aagagtaaca ttttcctaat
     3001 tgtgacatgg atgtcacaat tccaaacgct ctccgagggt tttcgctgtc acaagtgaca
     3061 acgaaaaaag gagccgaaag cgtatcacgc tatcaactcc ttttatgctt tattttgctt
     3121 cacgcaaaat aatcgcttat cgtaaattca cgtcattaaa tattgacgta aatttactct
     3181 cactcatctg acttttctta ttcggtatca ctccgaataa gtcgtcagat tcatcgggat
     3241 aatctcgttc gcttggcgct gatttttcat cagcaagcca ctcattatcc actgtttttt
     3301 cgtgttgctg atcgtcagaa attgacgata accaccgctc aaaatcagca aaagtttcaa
     3361 acccaaaacg cttgcgaaga gccttgccca ttgcagcatt ttctttctca atcaagcgtt
     3421 ttttctgttg gcgaagtttc gcttgttctt tttttaattt ttcttcttgc gctttaatat
     3481 ctgctaaagt cattcccata aactacatct ccttttcttt ggaattaata acggaaattt
     3541 ggtttaactg cataacatga ctcattaatt tcaaccaaaa ttctttttct gattcatcag
     3601 ttgtttgcgc taaatgctta tgaacaaatt cattagtcaa aactgaagat tttgctagat
     3661 cagcattgat aaccgagttg agaacatcca taattcgttc aagcatttca ctataattat
     3721 cttcatccgg caaattcaaa taatcagcta accgttcata catcaattca attctatcga
     3781 ctgtttcttc tctcaaatca attttatcca tgtcacacct cacttccaga attgccacca
     3841 ttttcgattt tttaattctt gattttctag taacaactga tcgttttttt gttgctgaag
     3901 caaagtcaat ttttgttggt cacgaatcat ttccgttaat tcagaaatat gcctatcttt
     3961 ttccgctaat tgttcacgca aaaattcatt ttctttttct aacgggaaat cattgcctgc
     4021 atcattgacc ggtaaatcac cagtcaattg accacctttt gaccgataaa ttgaccgcac
     4081 aacaccaatc aattccttgt ctaacatgat aaccccatta tctttatacc gagcaaggtc
     4141 ataacctgca ttgaccagtt gattgcgcac tgtattttta gatataccca actcatcagc
     4201 aaggtttttt atggtcattt tttctggcaa atcagtcatt atcttctccg ttactttcag
     4261 ctaccccata aacatattta acagcatgct tagggataat gattggggaa tcaattttat
     4321 tatttttcaa aatcaactca tactgcgtta catcaagtaa cttaccggac atttttttgc
     4381 tatcc
//
LOCUS       DAPBCF010000122         4319 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.127, whole genome shotgun sequence.
ACCESSION   DAPBCF010000122 DAPBCF010000000
VERSION     DAPBCF010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.127"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            381..2348
                     /locus_tag="RD508_002873"
     CDS             381..2348
                     /locus_tag="RD508_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009321393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737382.1"
                     /translation="MKRFLKIFIFLEIILFVYIFNTSIYNIYEKNNIATDNLKGYVLE
                     ETSPEILDKFYTIFTEEYSQNKLELINNKLTSTDKSVYDLYCYPLNEFVQKQPISNSI
                     LLQYHKLQKEDFLDSVGVFYTDLQANEIREIESQLAVTISVFENEAIPYSMILELYLL
                     NFVILFVVLQIIYCIYTSDSLKKKGIKKSMGFSAMHILKEQINNIVKYFIVICSVLFI
                     LLNLYYALTNRFNISYLTISIFFFAIILVINILCVLITSFLIKFVSLEAMIKNKTLNS
                     GTNLIVQTIKIVFSVIITITTISLLNQGNEFKQSQQDILDYKYLDGYFTANGFNSLEY
                     EYALENPEQFEEYSNSMLELYNNHHALLCDYAGSSEAQGEFSKSRPYYIQQTIIANRN
                     YISEFSNIQVNGKSLNEDIYDTPTILVSRKYKSDETFIKEHITQEYFRLMNYNQFYGI
                     PEKERHINEFNIVYVDDNSTIKVNTENGFSDMSEPIIIIDTGNFAGLYYLDSLNTRNL
                     FFQMDSREEFSSLLAEYGLKQLVTAGTLLTPYLMQLENVTFVLKTLTMFAIVFIISLL
                     FILYISNYVDIFVNRKKYATKEIMGFSHFKTLKNRYIFWGIELIASCILTAINYNFAC
                     LFAIILIDYIFCELLYRIYILNALYEIEKGA"
     gene            2351..3001
                     /locus_tag="RD508_002874"
     CDS             2351..3001
                     /locus_tag="RD508_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7737383.1"
                     /translation="MSLITLKNIKKVYGKNQILFENLSLEIEKGEFVGLVGKSGAGKT
                     TLLNIIGLITDISEGIITIDGQQKLSVNSRNAMLLRRYTIGYLFQNYGLIEDESVLWN
                     LKLALEYKKMKKEDKLKVINEYLKQFNLSDMLNKKIYQLSGGEQQRIAIIKLILQGSQ
                     IILADEPTSGLDKENEQVVMKLLKELNEKGITIIMVTHNMDLRNYFSRVINVETFR"
     gene            complement(3461..4075)
                     /locus_tag="RD508_002875"
                     /pseudo
     CDS             complement(3461..4075)
                     /locus_tag="RD508_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1513 a          597 c          729 g         1480 t
ORIGIN      
        1 cgatttcttg aagtgagtaa ggaatgcttt gaatggccct ttttacaagc tgcgcatctt
       61 ttttatttcc gcaagaatgg ccaataattt cacgattgaa taaatcaatc atcaaacaaa
      121 tataagccca atttgtcccg acccgaacat aagttaaatc cgtgacaacc gctgacaatg
      181 cttttgtttg agtaaacttt cgatctaagt gattcgcaat tttcttttga ttgctttggc
      241 acgatcataa agacgggagc agatattgtc tattgatata atgatagtag acaaacagag
      301 ttggctgatt agctaaagca tatcgagtat aatttgaata ttagacgcat gatttatcag
      361 tgtaagaaag ggtgaggatt atgaaaaggt ttttgaaaat atttatcttt ctcgaaataa
      421 tactttttgt atatattttt aatacttcta tttacaatat ttatgaaaag aataatattg
      481 cgactgataa tttaaaagga tatgttttag aggaaacatc gccggaaatt cttgataaat
      541 tttatacgat atttacagaa gaatattccc aaaataaatt agagcttatc aataataaac
      601 ttacttctac ggataaatct gtctatgatt tatattgtta tccgctaaat gaatttgtgc
      661 aaaaacagcc tatatcaaat tctattctgt tgcagtatca taaattgcaa aaggaagatt
      721 ttttggatag tgtcggggta ttctatacgg atttgcaagc caatgaaata cgtgaaatag
      781 aatctcaact ggctgtaaca attagtgttt ttgaaaatga agctatcccg tatagtatga
      841 tattagagtt gtatcttctt aattttgtaa ttttgtttgt tgtacttcaa ataatatatt
      901 gtatttatac atctgatagt ttgaaaaaaa aaggtattaa aaaaagtatg ggcttttctg
      961 ctatgcatat tttaaaggag caaatcaaca atatagtaaa atattttatt gtgatatgtt
     1021 cggtgttatt tatcctgctg aatttgtatt acgcattaac aaatcgtttt aatatttctt
     1081 atttaacaat aagtatattt ttctttgcga ttattttggt tataaacata ctttgcgttt
     1141 taattaccag ctttttaatt aagtttgttt ctttggaggc aatgattaaa aacaagactt
     1201 taaatagcgg tacaaatctt atagttcaga ctataaaaat agttttttca gtaataatca
     1261 caattaccac tatttcatta ttgaatcaag gaaatgaatt taaacaaagc caacaggata
     1321 ttttagatta taaatatctg gacggatatt ttacggctaa tggttttaat tctttagaat
     1381 atgaatatgc attagaaaat ccagaacaat ttgaagaata ttctaattcg atgttagaac
     1441 tgtataataa tcatcatgcc ttgttatgtg attatgctgg tagcagtgaa gcacaagggg
     1501 aatttagtaa atctcgtcca tattatatac agcaaacaat aattgcaaat agaaactata
     1561 ttagtgagtt ttcaaatatc caagttaatg gaaaatcatt aaatgaggat atatatgata
     1621 cgccaacaat attagtttcc cgtaaatata aaagtgatga aacttttatt aaagagcata
     1681 taactcaaga gtattttcga ctgatgaact acaatcaatt ttatgggata cctgagaagg
     1741 aaaggcatat caacgaattt aatattgtgt atgtcgatga taattctact ataaaagtta
     1801 atacagaaaa tggcttttca gatatgtcag aacctattat cattattgat acaggcaatt
     1861 ttgcaggtct ttactatttg gattctttaa atacaagaaa tttatttttc caaatggatt
     1921 caagagaaga attttcttct ttattagcag agtatggttt aaaacaatta gttacggcag
     1981 gaacattact tacaccatac ttaatgcaac tggaaaatgt gacctttgtc cttaaaacac
     2041 tcacaatgtt tgcgattgtc tttataatat cattactgtt tatcttgtat atttcaaatt
     2101 atgtagatat ttttgtgaat cgaaaaaaat atgcaactaa agagattatg ggattctctc
     2161 attttaaaac attaaaaaat cgttatatat tttggggaat agagttgatt gcatcatgta
     2221 tattgactgc tataaattac aattttgctt gtctttttgc aattatactt attgactata
     2281 tattctgtga attactttat agaatttata tcttaaacgc tttgtatgaa atagaaaagg
     2341 gggcataagc atgtcattga ttacattaaa gaacataaaa aaagtatatg gtaaaaatca
     2401 aattttattc gagaatttgt cgttagaaat agaaaagggt gaatttgttg gtcttgtagg
     2461 taaaagtggt gcaggtaaga caactctttt aaatataatt ggattgatta cagacatatc
     2521 agagggaata attactattg acggtcaaca aaaattatca gtaaacagta gaaatgcaat
     2581 gcttttaaga cgatatacga taggctatct atttcaaaac tatggactta tagaagatga
     2641 aagcgtatta tggaatttaa aattagctct tgaatataaa aaaatgaaaa aggaagataa
     2701 actgaaagta atcaacgaat atttaaaaca atttaatttg agcgatatgc tcaataaaaa
     2761 aatatatcag ttaagcggtg gagagcaaca gcggattgca attatcaaat taattttaca
     2821 aggaagtcaa attatactag ccgatgaacc aacttctgga cttgataaag aaaatgaaca
     2881 ggtagtgatg aaacttctga aagaattgaa tgaaaagggc attactataa ttatggtaac
     2941 tcataacatg gatttgcgta attatttttc cagagttata aatgtagaaa cttttagata
     3001 gtttattaaa gggagatata cttttttgtg caatctccct tgttcttttt ctgtcatatc
     3061 aagactcgtt caataatggt aaattcgtgg taaaatagct acttttttag ttgatgaata
     3121 gcccttaaat actgtattta tgcggataat cggatttttt ataccaagtt tggatatatc
     3181 aacaaatcat ttgataatta tgatcttggt tttataatta atttaaaaaa aataaaaact
     3241 atcgatgact tactcacaaa taatttagtt ctcaaaaaag cgtactgtga tacattctaa
     3301 tgacgagagc gtctttaccg gaaaaatcaa tcttttagat tcaaaaaaac tagtactttc
     3361 tataatagat tacgaaagca tcacaaagac gaacaaaaaa aacaataaat atagatgcag
     3421 actgtagaca tcatccataa aatggacttt gtctacagtc tgaaacgaga tctttcttct
     3481 tacgtgaagg aagaatatcc agtaatttcc cagtatcgcc atccatacaa gaaaaagaat
     3541 agggaccgac ttgatttttc aatgaacgaa attcatccac caatgaacag cgaggcaacc
     3601 aattcctttt cacgtttgtc atggggagca gagaagcgag tgttcgcgaa acggttgacc
     3661 aagaaacgcc gcaatgttta gaaatcgtcg tcattgcttg tttttcagtc aattcctcca
     3721 atattttata atgtacttgt ttggcgataa aacagttttt ttcaacaatg taggtattcg
     3781 ccgtaaaata ggtgtgacag ccacgacaga ggtaccgttg ctttgccaaa gcaagataag
     3841 tccgttgatt cgcacactta ttgagaagga ccagcgattt tttctttccg ctcttaacga
     3901 tcagcccatg ttgcttcacc tgtttacact gaggacagcg ctgaatcgtt ttaatgagcg
     3961 tggcagaaac aacgatactg ttgattgaat gtattttttt cttctcgaca tgagtgattt
     4021 gaatgttttt atctttgatt cctagtaata gtttgataag atgaagatca ggcatacaga
     4081 acgctccttt gattgtgttg tggtgattca attctaacgg agcttctgta tgttttgttt
     4141 ttttatgctc aaaaggactg atagaatgat tttctatcag tcctagaaat tatagcgccg
     4201 gaaaagtttc cgagcaccaa aatacccatt tctcactgaa gcaatgatga ttgatcgatt
     4261 gcttgagttt tctgcgcctc taaaggaggc gtatcccttt tttcatgaat tagtcgaag
//
LOCUS       DAPBCF010000123         4157 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.128, whole genome shotgun sequence.
ACCESSION   DAPBCF010000123 DAPBCF010000000
VERSION     DAPBCF010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.128"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            179..775
                     /locus_tag="RD508_002876"
     CDS             179..775
                     /locus_tag="RD508_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDT7737384.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="RD508_002877"
     CDS             899..2698
                     /locus_tag="RD508_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDT7737385.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="RD508_002878"
     CDS             complement(2976..3188)
                     /locus_tag="RD508_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737386.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3650..3799
                     /locus_tag="RD508_002879"
     CDS             3650..3799
                     /locus_tag="RD508_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737387.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            complement(4052..>4157)
                     /locus_tag="RD508_002880"
     CDS             complement(4052..>4157)
                     /locus_tag="RD508_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7737388.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1228 a          706 c          729 g         1494 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctataatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacaaaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca ttccaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtataa tatttaatat aatcttaatt gtcaaattaa gttagacaga tcatcaatac
     4081 ttacgtaact caaaaatact tccaaaggtg ttcgataatc cagtgatttt ctaggaatat
     4141 tatttcgttt agatgcg
//
LOCUS       DAPBCF010000124         3992 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.129, whole genome shotgun sequence.
ACCESSION   DAPBCF010000124 DAPBCF010000000
VERSION     DAPBCF010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.129"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..386)
                     /locus_tag="RD508_002881"
     CDS             complement(<1..386)
                     /locus_tag="RD508_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HDT7737389.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPT"
     gene            complement(383..2482)
                     /locus_tag="RD508_002882"
     CDS             complement(383..2482)
                     /locus_tag="RD508_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HDT7737390.1"
                     /translation="MTINEVIYSPKHPLFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLGNLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPLYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETMNYFAQLFGQLSMSDDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERYPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACSGLAEIFEALEQLSLSERYKDIACKLKESICKQMTIDGTF
                     GEQFLEGIGDEEKTTYSVKNYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDPLYQNTMTFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSDMHNH
                     QAFVTRLEELICLADLDGSWWWWPYRLEAKQGEVVRDFGCGKCGWASGLFVSIMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIYIQRRKR"
     gene            complement(2533..3354)
                     /locus_tag="RD508_002883"
     CDS             complement(2533..3354)
                     /locus_tag="RD508_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7737391.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLGCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(3351..>3992)
                     /locus_tag="RD508_002884"
     CDS             complement(3351..>3992)
                     /locus_tag="RD508_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7737392.1"
                     /translation="FMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLA
                     VLGLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFVMWFVHYALYALIPFFAVL
                     FGADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAY
                     LELPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
BASE COUNT         1229 a          927 c          677 g         1159 t
ORIGIN      
        1 gtaggattaa ccactatagg caacgagttc acctcgcaac gctctccaaa cccattacaa
       61 aagaaatccc ctaaaggact ttcaacagcc gggctatccg acccatccca ataaattctt
      121 aagattaaat cacgtaaaac aaaactgcca aattctgttc gatcacgaat cgtcatccac
      181 atatgacgaa ttattcccgt tccagtaata tccgcaatca cagtttcttc accagaagtc
      241 agcggaattg cgccacgacc tttgcggctt ggtcctagct cgcttggcaa catcgcagct
      301 ttacctttct cgcctgttgg attttcggga gtgattgctc gactctggat ttttttaaat
      361 tgggtaatat tttttagtat actcatcttt ttctcctttg aatgtaaatc gtttttccct
      421 tttctacgtg aagaattttt ttcgtatcac ttattttcaa tggcttttct gacaaatttg
      481 aaatactcaa ctcggattgc gtacattcaa tcgaaatgaa ggcttgaccg aacttcaaat
      541 ttttccaaga aaacgttaaa ttatcaacag gatcaatttg caatactcct tttttgaatt
      601 tcaatccgaa atattgactg atcattatac tgacaaaaag gcccgatgcc cagccgcatt
      661 tgccgcagcc aaagtctcgc acaacttctc cttgtttagc ctctaaacga tacggccacc
      721 accaccatga accgtctaaa tctgccaaac aaatcagctc ctctaatcgg gttacgaagg
      781 cttgatggtt gtgcatgtca ctcattaaaa cagtgataaa gccaggaaaa gtggcgccgg
      841 attctaatcc ccaagtgatg cctttgattt cctcgctata agttggattg aaagaactag
      901 cagaaaaggt catggtgttc tgatataaag gatctttatt atctaaaaat tgataaaaag
      961 gcatcaacgt agtgtctgat tcttctccat catgcatcaa taaattgatt ttcccatcca
     1021 caatcacatc acttaaaaag attaaccctt gctcaagaat cggtttttga tagttcttca
     1081 ctgaataggt tgttttctcc tcatcaccga tcccctccaa aaattgctcc ccaaaagtac
     1141 catctatggt catttgttta caaattgatt cctttagttt acaggcgatg tctttgtatc
     1201 gctcgctaag actcagttgt tctagggctt caaaaatttc tgcaagtcca ctacaggcct
     1261 tccaaagaca aagattgctg ccggtatgat actttccaag tgcaaaggcg tctgataacc
     1321 aaacagatgg aaaaagcatt ggttcccctg accgacgttg agctaatatg tcctcaataa
     1381 ttcttgaagc attcagtaga acctgcggat accgctcaaa gaattttgta tccccagtat
     1441 gttcaaaata aagactagcc agtaacgcac tggataacga attactcaga gaatgattga
     1501 tacctcctgt aaattttgaa ccaggaaact taacgccata ttgatcaaac catagaaccg
     1561 ttttttgaca taactccggt tcaaacatgg tgaatggcaa tgatgcgtaa tacatatcct
     1621 tattccaaat tcgattagta gcaggatagc tgccccaatt gctgccgacg acctgtccct
     1681 gtcgattcat accgaaacta gaaaagcttt gataaagtgc acgacgatag agatggacaa
     1741 ctctatcgtc tgacattgac agctgcccaa atagctgagc aaaatagttc attgtttcct
     1801 tcagccattt ttcgatatca gattcctgaa aagtcattac ttcttcaaaa gcatttgggt
     1861 ccacaaaagc aatggcgaag cttgccactt cctgttgtgc gatcgtgtcc ttatttcctt
     1921 tttgagaaat caacacattt tgctgatccg aatacttctc ttggtacaaa ggcacatctt
     1981 tcactgaaac ttgaaggctt tcgtgtgttt cattcacaat gtaaacctgt tgaacaagca
     2041 tacttaaacg cttattagcc agtattggag caaaggatac tacaatgacc ttaaacgtcg
     2101 aataatgatg aatatatcta ggcaaacagt cttgaatcac atcgacttca atacgatgat
     2161 ccgattctga caaatggtag acaatcccgt ttacttcaac ctttaaggat aacgaattgg
     2221 tttgagaaag ctgtttattg acccaaacac ctggtttttc ctcagttagt aaattttctc
     2281 gataaaaggt caacgtttga atcgtcccgc aaacatcaag gtttcctaat gtcttttgat
     2341 tacttacatc aaaggtcaat ccctttacat caggaatatt ccgatagtag ctgtattcgt
     2401 ttgaagtagt cacatttccg tcgtttaact cagcattaaa taatgggtgt ttgggtgaat
     2461 aaattacttc attaatagtc atcttttccc tccttgctaa aaaaactgca gcctagtagc
     2521 tgcagcttcc tactatgcga ttccaagtaa tgacaataaa attcccaaga cgaccattcc
     2581 aaaaataatt ttgatgacgc cgactttttt atctagtaat ttgaaacagc ccaatgttac
     2641 caataacggt acaattcctt taaaaatact atcgaggatt tcttggacat tcattagttc
     2701 ttcgcccttc attgaaaagc tcaaaacggt attgaatttg accatactga tcgtcattgc
     2761 gcctaccatg atcagaccca agatactagc agcttttgtc agaatttcaa ttaacccgtt
     2821 cgcatacagc ttttcaatat atttagagcc taatgaatag cctaaaacgc cgccatagta
     2881 tcgcatcaaa taattaggta tattgaacat aactaaaaag ataattggtg ccaaaatatt
     2941 tccggcattg gctaagttga tcgctagtcc cgcggtaacg acacgccaaa ctccccagaa
     3001 caatgaatcg ccaattccag ccaatggtcc catcaaactc gttttgatcg cgttgatact
     3061 ttccacgtca aaaccagctt tttcagaatt ttccttctcc atcgatgccg caatccccat
     3121 gacaaaggac gcgcaaggaa tggtcgtcga aaaatactgt gtatgacgtt ccagcgccgc
     3181 agctcgatct tcttcacttt tgtagaaatg attaatgaag ggcatcatag aataggcgaa
     3241 accaccgccg cccatcgtca ccggattcac cgaagcatac atggtcatcg agcgccaaaa
     3301 catcttccga accaattttt tctcatcttt agaaattcca tcagctaatt tcattgaaag
     3361 aaatcctcct cttcttggtc aagcgttgca tttacagcag catcgctttg aactgcatga
     3421 acagatatat tttttagttg tagatctctt tgggctataa caattgcaat aatcgttcca
     3481 actgcggcaa ttgcaatcaa tggtaactcg agatacgcca taacaacggc cccaaagaaa
     3541 aaccacacag caatattttt actccaaagc atccgtaaca gcatagccat cccaactgcc
     3601 ggcagcagat ttccagcgac tgttaatccg ttcatgatga cctctggaat attatccaag
     3661 acgcttttga caacatctgc tccaaataaa acggcaaaga atggaataag agcataaagc
     3721 gcatagtgga caaaccacat aacgaagtgc agattgatga ttcctttttg atcaccagat
     3781 tttgcaaatt tgaaaaattt agcagccatc ggtccacata caaaagaaaa aatcatattc
     3841 attaactgta atcctaatac tgctagtgga aagacaatgg gaataatcgc atccacgttt
     3901 cctcccattt tgattgcgaa cgctgtagcc aacccagcag ccaaagaagg ctccgccgta
     3961 ctagagattc cgatattgac gacacccata aa
//
LOCUS       DAPBCF010000125         3992 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.130, whole genome shotgun sequence.
ACCESSION   DAPBCF010000125 DAPBCF010000000
VERSION     DAPBCF010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.130"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..386)
                     /locus_tag="RD508_002885"
     CDS             complement(<1..386)
                     /locus_tag="RD508_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HDT7737393.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPT"
     gene            complement(383..2482)
                     /locus_tag="RD508_002886"
     CDS             complement(383..2482)
                     /locus_tag="RD508_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HDT7737394.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(2533..3354)
                     /locus_tag="RD508_002887"
     CDS             complement(2533..3354)
                     /locus_tag="RD508_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7737395.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(3351..>3992)
                     /locus_tag="RD508_002888"
     CDS             complement(3351..>3992)
                     /locus_tag="RD508_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7737396.1"
                     /translation="FMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLA
                     VLGLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVL
                     FGADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAY
                     LELPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
BASE COUNT         1229 a          920 c          688 g         1155 t
ORIGIN      
        1 gtaggattaa ccactatcgg caacgagttc acctcgcaac gctctccaaa cccattacaa
       61 aagaaatccc ctaaaggact ttcaacagca gggctatccg acccatccca ataaattctt
      121 aagattaaat cacgtaaaac aaaactgcca aattctgttc gatcacgaat cgtcatccac
      181 atatgacgaa ttattcccgt tccagtaata tccgcaatca cagtttcttc accagaagtc
      241 agcggaattg cgccacgacc tttgcggctt ggtcctagct cgcttggcaa catcgcagct
      301 ttacctttct cgcctgttgg attttcggga gtgattgctc gactctggat ttttttaaat
      361 tgggtaatat tttttagtat actcatcttt ttctcctttg aatgtgaatc gtttttccct
      421 tttctacgtg aagaattttt ttcgtatcac ttattttcaa tggcttttct gacaaatttg
      481 aaatactcaa ctcggattgc gtacattcaa tcgaaatgaa ggcttgaccg aacttcaaat
      541 tcttccaaga aaacgttaaa ttatcaacag gatcaatttg caatactcct tttttgaatt
      601 tcaatccgaa atattgactg atcattaggc tgacaaaaag acccgatgcc cagccgcatt
      661 tgccgcagcc aaagtctcgc acgacttctc cttgttgagc ctctaagcga tacggccacc
      721 accaccacga accgtctaaa tctgccaaac aaattagttc ttctaatcgg gttacgaaag
      781 cttgagggtt gtgcagctcg ctcattaaaa cagtgataaa gccaggaaaa gtggcgccgg
      841 attctaatcc ccaagtgatg cctttgattt cctcgctata ggttggattg aaagaactag
      901 cagaaaaggc catggtgttc tgatataaat gatctttatt atctaaaaat tgataaaaag
      961 gcatcaacgt agtgtctgat tcttctccat catgcatcaa taaattaatt tttccatcca
     1021 caatcacatc acttaaaaag attaaccctt gctcaagaat cggtttttga tagtgcttca
     1081 ctgaataggt tgttttctcc tcatcaccga ttccctccaa aaattgctca ccaaaaggac
     1141 catcgatagt catttgttta caaattgatt cctttagttt acaggcaatg tttttgtatc
     1201 gcttgctaag actcagttgt tctagggctt caaaaatttc tgcaagtcca atacaggcct
     1261 tccaaagaca aagattgctg ccggtatgat actttccaag tgcaaaggcg tctgataacc
     1321 aaacagatgg aaaaagcatt ggttcccctg accgacgttg agctaatatg tcctcaataa
     1381 ttcttgaagc attcagtaga acctgcggac accgctcaaa gaattttgta tccccagtat
     1441 gttcaaaata aagactagcc agtaacgcac tggataacga attactcaga gaatgattga
     1501 tacctcctgt aaattttgaa ccaggaaact taacgccata ttgatcaaac catagaaccg
     1561 ttttttgaca taactccggt tcaaacatgg tgaatggcaa tgatgcgtaa tacatatcct
     1621 tattccaaat tcgattagta gcaggatagc tgccccaatt gctgccgacg acctgtccct
     1681 gtcgattcat accgaaacta gaaaagcttt gataaagtgc acgacgatag agatggacaa
     1741 ctctatcgtt tggcattgac agctgcccaa atagctgagc aaaatagttc aatgtttcct
     1801 tcagccattt ttcgatatca gattcctgaa aagtcattac ttcttcaaaa gcatttgggt
     1861 ccacaaaagc aatggcgaag cttgccactt cctgttgtgc gatcgtgtcc ttatttcctt
     1921 tttgagaaat caacacattt tgctgatccg aatacttctc ttgatacgaa ggcacatctt
     1981 tcactgaaac ttgaaggctt tcgtgtgttt cattcacaat gtaaacctgt tgaacaagca
     2041 tacttaaacg cttattagcc agtatgggag caaaggatac tacaatgacc ttaaacgtcg
     2101 aataatgatg aatatatcta ggcaaacagt cttgaatcac atcgacttca atacgatgat
     2161 ccgattctga caaatggtag acaatcccgt ttacttcaac ctttaaggat aacgaattgg
     2221 tttgagagag ctgtttattg acccaaacac ctggtttttc ctcagttagt aaattttctc
     2281 gataaaaggt caacgtttga atcgtcccgc aaacatcaag gtttgctaat gtcttttgat
     2341 tacttacatc gaaggtcaat ccctttacat caggaatatt ccgatagtag ctgtattcgt
     2401 ttgaagtagt cacatttccg tcgtttaact cagcattaaa aaatgggtgt ttgggtgaat
     2461 aaattacttc attaatagtc atcttttccc tccttgctaa aaaaactgca gcctagtagc
     2521 tgcagcttcc tactatgcga ttccaagtaa tgacaataaa attcccaaga cgaccattcc
     2581 aaaaataatt ttgatgacgc cgactttttt atctagtaat ttgaaacagc tcaatgttac
     2641 caataacggt acaattcctt taaaaatact atcgaggatt tcttggacat tcattagttc
     2701 ttcgcccttc attgaaaagc tcaaaacggt attgaatttg accatactga tcgtcattgc
     2761 acctaccatg atcagaccca agatactagc agcttttgtc agaatttcaa ttaacccgtt
     2821 cgcatacagc ttttcaatat atttagagcc taatgaatag cctaaaacgc cgccatagta
     2881 tcgcatcaag taattaggta tattgaacat aactaaaaag ataattggtg ccaaaatatt
     2941 tccggcattg gctaagttga tcgctagtcc cgcggtaacg acacgccaaa ctccccagaa
     3001 caatgaatcg ccaattccag ccaatggtcc catcaaactc gttttgatcg cgttgatact
     3061 ttccacgtca aaaccagctt tttcagaatt ttccttctcc atcgatgccg caatccccat
     3121 gacaaaggac gcgcaaggaa tggtcgtcga aaaatactgt gtatgacgtt ccagcgccgc
     3181 agctcgatct tcttcacttt tgtagaaatg attaatgaag ggcatcatag aataggcgaa
     3241 accaccgccg cccatcgtca ccggattcac cgaagcatac atagtcatcg agcgccaaaa
     3301 catcttccga accaattttt tctcatcttt agaaattcca tcagctaatt tcattgaaag
     3361 aaatcctcct cttcttggtc aagcgttgca tttacagcag catcgctttg aactgcatga
     3421 acagatatat tttttagttg tagatctctt tgggctataa caattgcaat aatcgttcca
     3481 actgcggcaa ttgcaatcaa tggtaactcg agatacgcca taacaacggc cccaaagaaa
     3541 aaccacacag caatattttt actccaaagc atccgtaaca gcatcgccat cccaactgcc
     3601 ggcagcagat ttccagcgac tgttaatccg ttcatgatga cctctggaat attatccaag
     3661 acgcttttga caacatctgc tccaaataaa acggcaaaga atggaataag agcataaagc
     3721 gcatagtgga caaaccacat aaagaagtgc agattgatga ttcctttttg atcaccagat
     3781 tttgcaaatt tgaaaaattt agcagccatc ggtccacata caaaagaaaa aatcatattc
     3841 attaactgta atcctaatac tgctagtgga aagacaatgg gaataatcgc atccacgttt
     3901 cctcccattt tgattgcgaa cgctgtagcc agcccagcag ccaaagaagg ctccgccgta
     3961 ctagagattc cgatattgac gacacccata aa
//
LOCUS       DAPBCF010000126         3781 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.133, whole genome shotgun sequence.
ACCESSION   DAPBCF010000126 DAPBCF010000000
VERSION     DAPBCF010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3781
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.133"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..1175)
                     /locus_tag="RD508_002889"
     CDS             complement(<1..1175)
                     /locus_tag="RD508_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7737397.1"
                     /translation="MKKSAKDRVFDELIRLTGNKSSVTAEKISKNLGISRQNASHYLT
                     RLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQINEAFHSVVGHDGSLREVIQKCIAAV
                     KYPPNGLSVLINGATGVGKSFLATKIFEYAIHEQIIEEDAPFAILNCADYADNPELLS
                     ATLFGYKKGAFTGAEKDTEGLLATANNGYLFLDEVHRLSKENQEKLFVFIDTGNYRPV
                     GENVNWYSAKVRFIFATTEKSEDYLLDTFDRRIQISVMLPTFEDRPIRERLELIQLFF
                     QNEADILQKDIIVSKEALSLMLSHPFSGNIGKLKNIIKISCADVYSRTREEPLTIGKN
                     EILIQLNMLESEVESLPIASLLIKKNQKIKTDRIKPFDYDSILEKITQLINEGNFNE"
     gene            1658..1873
                     /locus_tag="RD508_002890"
     CDS             1658..1873
                     /locus_tag="RD508_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HDT7737398.1"
                     /translation="MKKFIIPCIFLFLSILLFSTSILVGSYLDSSGMLIEPAFFCVPL
                     GYLTLGLAFFTALYSFVKQRLLKKYSA"
     gene            2734..3693
                     /locus_tag="RD508_002891"
                     /pseudo
     CDS             2734..3693
                     /locus_tag="RD508_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         1195 a          770 c          596 g         1220 t
ORIGIN      
        1 ttttcattga aattaccttc atttatcagc tgagtaattt tttccaaaat cgaatcataa
       61 tcaaacggtt tgattcgatc cgtttttatc ttttgatttt tctttatcaa taaactagca
      121 atcggcaagc tttctacttc ggattccagc atatttaact gaatcaagat ctcatttttc
      181 ccaatcgtta atggctcttc ccgtgttcga ctgtacacat ccgcacaact gattttaata
      241 atattcttca gcttaccaat attcccacta aagggatgag ataacattag agacaaagct
      301 tcttttgaaa caataatatc tttttgtaaa atatccgctt cattttgaaa aaataattga
      361 atcagctcta accgttctcg aatgggacga tcttcaaaag ttggcaacat aacactgatt
      421 tgaatacgtc gatcaaaggt gtctaataaa taatcttcac ttttttccgt cgtggcgaag
      481 ataaaacgaa ccttagcaga ataccagttt acattttcac cgactggacg ataatttcca
      541 gtatcaataa aaacaaagag cttttcttga ttttctttcg acaaacgatg gacctcatca
      601 agaaaaagat agccattgtt ggctgttgcc aataacccct ctgtatcctt ctcagccccc
      661 gtaaaggccc ctttcttgta tccaaacagt gttgccgaaa gcagttcggg attgtccgca
      721 taatcggcac aatttaaaat agcaaatggt gcatcttctt caataatttg ctcgtggata
      781 gcgtattcaa aaatttttgt ggctaaaaaa ctttttccaa cccccgtggc tccatttatt
      841 aatacactga gtccgttagg cggatatttg acagctgcaa tacatttttg aatgacctct
      901 ctcagacttc cgtcatgacc caccacagaa tgaaaggctt cgtttatttg ctccgtatta
      961 tctacaaccg catattcatc taaaggcttc cacaaaacag gctttcccgg taatttctcg
     1021 acctttttat cttccactaa tctcgtcaaa taatggctgg cattctgacg agagatacct
     1081 agattcttcg aaattttctc ggcagtgaca gaagacttgt tccctgttag tcgtatcagc
     1141 tcatcaaaaa ctcgatcttt agcgctcttt ttcattttcc cctccagttc aacgtgtcta
     1201 gaagcataat aaactatcgg ctacaatatg tctattctat atttctgttc caattttact
     1261 ttgaaacaaa aataatcgag cttaaactga tattagttat aaaactatag ttagattacc
     1321 aatcttcctc tcatacaata aacttctctc acctgcatcc aacctactta tgtgaaagaa
     1381 taactgccga ttatttatct tttttacagt tactttcgaa cataaaaaaa tcaccttcaa
     1441 atactagaaa aactactatt tgatggtggt ttagaacaat ttccgttgat tcagtatcgt
     1501 ctggtcccac atcctctgtc tcattaatca caatagcata ctccaaagga taaagctggt
     1561 tgatatctca atgcctttca cacctatcaa ttttgtcaca cttatctttt cctaggttct
     1621 attctatata atctagaaaa acaaagaagg agacaccatg aaaaaattca ttattccttg
     1681 tatatttctt ttcttgagta ttttgttatt ttcaacttcc atcctagtcg gttcttacct
     1741 cgattcaagc ggaatgctga ttgaaccagc gttcttttgt gttccgttgg gctacttaac
     1801 attaggactt gctttcttta ctgccttata cagtttcgtc aaacaaagat tattgaagaa
     1861 atactcggct tgatttgcac gtaaatcctc tgttgaagaa aagttagttt tttcaacaac
     1921 gaaccttcga gtattaagaa tggatgttga tgtagacatc aaacgtctgc ataaacattc
     1981 attttattcc tccattacca acaattattc ccaatcgcca aaagaagctt ttttcggaat
     2041 taccttctcc attttttcac ctgctggtta tattgtcttt tgtaataccg atagtcctct
     2101 tcaatcattt tcaatatgcg aaaagaacca attttaacat ggcactcaaa tcacaattcc
     2161 tagggcggcc aaaaagatac ggctcgttga tttcaagggt ttcaacgagt tcattgacaa
     2221 acccagcggt gctatcttct tttggaataa gaagttgtga tatctaaagt gagttgattc
     2281 atgttataat ttgtatgcat gattttgatc ctttcaaggg ttgaatgatt tagagtgcga
     2341 gtatcctctc gtactctttt attttaccta aaaagctcca gaaatgacga atgactcgtc
     2401 atttctagag cttttttcag agaattatgt cacaatctct ttttgttata ttgatattct
     2461 atatcttttt ttattggttt tattcccttg ttcgttatag actaaaatcc ttctttcagc
     2521 attattcaaa tcaaatggca acataataga gaaatttata gtatgtataa tcatctgaat
     2581 tcaatcaaat caaccggagt catatacgga gtcaaactat cccactgaga gtttattaaa
     2641 cgcagattgt aaaattaagc tagacaacta aaaaagtcat ttgtgctaca ctcaaaatag
     2701 ttccgaccaa agaattataa ggagtgaaga caaatgacct atacccatct tacaacaaat
     2761 gaactcgtga tgatagaagc ctatttcaat atgcatcaat ctgttaccgt agtcgctaag
     2821 acctcaaatc gttccagaca gaccatctac aatgtgtaca acttcctgaa acaaggccaa
     2881 tctatccatg actattacca acaatatcaa aaaaataaaa cacggtgcgg ccgacgaccc
     2941 atttgtttgc cagcagaaca agatgcgtat atccgaaaca aggtggcgca aggatggaca
     3001 cccgatgtga ttatcggtcg tgctgagttt tcaatttcat gttctgttcg aaccctttat
     3061 cgcaagttta aaacaaacta atttgattgc tcgaaactac ccatgaaagg aaaacggaaa
     3121 cccaacgggc ataaagaacg tcgagggaaa caagccttca aacggaatat ttcagaacgt
     3181 ctcacggact atcctgaatt tcaacaggaa tttggacatt tggaaggcga cactattgtg
     3241 ggtgtccatc ataaaagtgc tgtcatcacg ctggttgagc gcttgtcaaa agtgattatt
     3301 actttaaaac ccgaaggacg gaaagcacta gatattgaaa aagtgacaac tgactggcta
     3361 caaaagcttc cccgaaactt gttcaaatcc attacctttg attgcggaaa agaattttcg
     3421 aattggaaaa acatgagtaa tgctaacgat atttctattt attttgcaga tcctggaacg
     3481 ctgtcacaac ggggattaaa tgaacattct aatggattgt tacgtaaaga cggacttcct
     3541 aatacaatgg atttcaatca ggttgaccaa aaatttgtgg cggcggttgc ctccaaaaga
     3601 aatcatatac caaggaaatc tttaaattat cgaacatcgt tagaagtatt tttgagttac
     3661 ataagtgagg agcaattgtc taacttaatt tgacatttag aaaataataa accatatccc
     3721 atctattcaa ataatatttt accgattgaa agacttgcta atcaaagcag aatagtttat
     3781 a
//
LOCUS       DAPBCF010000127         3462 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.135, whole genome shotgun sequence.
ACCESSION   DAPBCF010000127 DAPBCF010000000
VERSION     DAPBCF010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.135"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(580..1596)
                     /gene="tsaD"
                     /locus_tag="RD508_002892"
     CDS             complement(580..1596)
                     /gene="tsaD"
                     /locus_tag="RD508_002892"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDT7737399.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(1593..2057)
                     /gene="rimI"
                     /locus_tag="RD508_002893"
     CDS             complement(1593..2057)
                     /gene="rimI"
                     /locus_tag="RD508_002893"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDT7737400.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2064..2606)
                     /gene="rimI"
                     /locus_tag="RD508_002894"
     CDS             complement(2064..2606)
                     /gene="rimI"
                     /locus_tag="RD508_002894"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDT7737401.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(2590..3312)
                     /gene="tsaB"
                     /locus_tag="RD508_002895"
     CDS             complement(2590..3312)
                     /gene="tsaB"
                     /locus_tag="RD508_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDT7737402.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
BASE COUNT          991 a          757 c          594 g         1120 t
ORIGIN      
        1 aaatatcagg gtcactgctt attttcctcc ctaaaacttc tgaaagatcc ggcagtttta
       61 gatcactgga caagactcaa agattttcta tgtgtgtttc agttatgtaa tattcactgt
      121 ttgcaaaaaa tactgttaga ttaactagat gaagcgtctt gtcctcatcc gatctagatt
      181 attcgatatt cctcgacaat aaacgattac tcagtgaggg caatcagagg aacggataat
      241 gataaataag ctgtaaaaaa tagcaaaata acaataatga ttaaaagtat gtaaaaaata
      301 gggctttgac aaaaacgtgt cacagcccta tttcgattaa acggtgtgta cctgtcaact
      361 cttcggtcac aagtcataat gttcataaac atgaggagct gttttttgaa attgttcctt
      421 gtgaatcaga gttaaacgac aggcttacga actcttgatt aaacggcgtt caaaagcttg
      481 catacgcggt aataagaaca gccaggtcaa aaacatgaga agccgttttt cctgggctgt
      541 tcttattact tgatgcaggg cagctttttc acaacctctt tattcagata aaaccaagct
      601 tggatcagca ttcaactgat agctagcaaa atttcttttt tgcatttcca catgtgctgc
      661 tgctccaatc attgcagcat tatctccaca aagtcgaaga gggggaatca ctagttctac
      721 ctcagggagt ttagttgcca aagcatcctg caatccttca cgcaaccctt gattggccgc
      781 tacacctcca gctataatca gttgcttgac tggataattt tgacaagctc gaagtgtttt
      841 agtaatcaat acatcgatca cacttgcttg aaagctagct gctaaatcat ttttgtctag
      901 atcttctcca cgctgttgtg cattatgcac caaattgata aatgcacttt ttaatccgct
      961 aaaactgaaa tcataattat cttcatggat catcgctcgc ggaaaatggt aattatcttt
     1021 tccctgatga gctagctgat cgatttcttt tccgcttggg taagaaagac ctaatactct
     1081 tccaactttg tcataagctt ctcctgctgc gtcatctctt gtctccccaa tgatttcata
     1141 tgatccatct tcttgcatat agactaattc tgtatgtcct ccgctaacaa gaagtgccat
     1201 caatggaaac tggaatggtt taaccagacg ggctgcatag atatgccctg ccatatggtt
     1261 tacaggaata agcggcaatt ggtgtgccca agcaaaagcc ttagctgcag aaataccaat
     1321 cagcaacgag ccgacaagtc ctggtccata agtgacagcg actgccgata aatcttctgc
     1381 cgacacacca gcttctacca gtgcatcttc caagcataag gtgatttgtt ctacgtgatg
     1441 gcggctagct acttcaggta ctacgccacc aaaacgttta tgactgttta tttgagaagc
     1501 aacgatgtta gataagatct ctgttccatt tctaacgacc gctacactcg tttcatcaca
     1561 acttgattca atcgccagaa tcaattcttc attcatttca tcgtctccgt ttttaacttt
     1621 ctgctcataa tgatcgcatc ttccgtcgga ttgcgataat atgatttccg tttacctaat
     1681 atacgaaact tttctgattc ataaagtttt cttgctgctt cattagatag acgtacttct
     1741 aaaaaaacat gcagcgaatc ttttatttgt tccgtaatca gtaattgtaa caaatgccgt
     1801 gcatgccctt ttccttgttc tgaaactgca acagcaatat ttgtgatctc gacttcatct
     1861 attactttcg agtatccaat aaagccacag atctggttat cttcagctaa aagcagataa
     1921 tcagagtgag gctgttggat gtctgccaaa aactgcattt tcgtccaagg tgaaccatgt
     1981 ggataagcat tttcgctaat catccatacg cattctgcca agtacgcttc atcaaaatct
     2041 ttttttctgc aaatcaacta atctcactca ttttctaaaa gttttatcat atccaacgca
     2101 tcttcttttg tttcagtgta atatcttttt ttgatcgttg ttgcttgaaa ccccaatttc
     2161 cgataaagtc tttgtgcatc ttgattactc atacgcactt ctaatgacat cgtctcacag
     2221 cgattcatta tagcaaagtt ctcgatttcg tcaataagca gcgaaccgat tcgtttacgc
     2281 tgatatgccg gtcgaacggc aatattcgtg atatggcaat ctaaaccgaa cgctcttgaa
     2341 ccgataaaac caatcattct tccattatca aagataccta gatatagatg aggaagcggt
     2401 gacttcaatt ctgatataaa ggcacttttt gtccatggca attcgccatt atagacttct
     2461 cgttcgacat ccagcagctc tttgatatct tctgtagtca attctcttag tacgtaacga
     2521 cgatcgattt gttcgactgt tttttctgta taaatcattt tatcttgaaa aaagcttctg
     2581 gcatacgctc taaatttttt caacataact ttcgtctcca ggtgtgtgcg tctccaacca
     2641 tttttcttct gcttctactc gttttaaata gcgaggaaga aaagcttgtt tctctgcaac
     2701 tggttcaact aaagcaccta attgagccac agttacacca cttggaatat cccatgctgg
     2761 aactgtatta atcatcgcac taggcaatat ttcctttatt tcagagaaga atttgtgaca
     2821 atcactcccg acgaaataaa tagcttcatt cagcttttgt agttgtgtga acaaatcaga
     2881 agcagaaata tgtacatctt caagtacagt ttctaatcta ttttctttcc agcggtatgc
     2941 cccagcgtat acattttttc ttcgagcatc aaacatgggc acaataatat tatccacacc
     3001 gatgcaatta gccgcgatgg ttttcagact agatactcct actagctctt tatctaatgt
     3061 ataagcaatc gtttttgctg tcgttacacc tatacgaagc cctgtataag aaccgggacc
     3121 atcagaaacc gcgattcggt caatgtcttt tggacttatt tgaagatctg caaacaattg
     3181 gtcgattgca ggcatcagtg ttacactgtg gttgcgtttg atatttgttt gtatttgtcc
     3241 aagaatttgt tcgtcttcta ccacaccgat cgccaaagtt tggtttgcag tatctattcc
     3301 taatgtaatc atatatttga tcctttctgc tatgacattc tcgccttcca ttgtagcata
     3361 cttttttatt ctgaggatga aaataccaaa ggcaaaacta gtacaataat acatgattat
     3421 ctgctggcgg gcaaattttg ccccttcctg aaacacaaaa aa
//
LOCUS       DAPBCF010000128         3391 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.136, whole genome shotgun sequence.
ACCESSION   DAPBCF010000128 DAPBCF010000000
VERSION     DAPBCF010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.136"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            647..964
                     /locus_tag="RD508_002896"
     CDS             647..964
                     /locus_tag="RD508_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDT7737403.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="RD508_002897"
     CDS             complement(1055..1420)
                     /locus_tag="RD508_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737404.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1628..2110
                     /locus_tag="RD508_002898"
     CDS             1628..2110
                     /locus_tag="RD508_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737405.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2307..3197
                     /locus_tag="RD508_002899"
     CDS             2307..3197
                     /locus_tag="RD508_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HDT7737406.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1172 a          519 c          619 g         1081 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
     1561 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
     1621 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
     1681 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
     1741 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
     1801 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
     1861 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1921 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1981 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     2041 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     2101 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     2161 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     2221 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     2281 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     2341 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     2401 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     2461 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     2521 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     2581 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     2641 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     2701 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     2761 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     2821 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     2881 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2941 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     3001 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     3061 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     3121 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     3181 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     3241 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     3301 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     3361 aaaagagcta cgacatagaa ctgtcgtaac t
//
LOCUS       DAPBCF010000129         3258 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.137, whole genome shotgun sequence.
ACCESSION   DAPBCF010000129 DAPBCF010000000
VERSION     DAPBCF010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.137"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(58..633)
                     /locus_tag="RD508_002900"
     CDS             complement(58..633)
                     /locus_tag="RD508_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7737407.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(638..1612)
                     /locus_tag="RD508_002901"
     CDS             complement(638..1612)
                     /locus_tag="RD508_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HDT7737408.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1636..1680)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1895..2863
                     /locus_tag="RD508_002902"
     CDS             1895..2863
                     /locus_tag="RD508_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7737409.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2960..3253
                     /locus_tag="RD508_002903"
     CDS             2960..3253
                     /locus_tag="RD508_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDT7737410.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
BASE COUNT         1072 a          612 c          645 g          929 t
ORIGIN      
        1 aataaatgaa aaaacagagc cagattagca ttattttgct aatccagctc tgtttattca
       61 gcctattttt ctttttgaat atatcaagcg ttgtggcaac atagtgatga ctaatgaaac
      121 aacgacgata gacaacaaac gatcaaggta gtctgtacct gcctgtacca agatcacact
      181 tgttgtctga cttaaaccta acccatgtaa tagctgaacg atcatactgg atcctgagga
      241 ggtgatcccg ccaaataact gaacggtaat gatcgaagaa acgatcgttc caggtaccga
      301 caaaatcaaa gcgagtaata acagtttcaa gctgttttta tctttgccga gatatcttgg
      361 caaaatcaat ccagcaagca agcctgtgag aatttggatt ggcgaataat acagagaaaa
      421 aatatctgta gtcactccac ttaaaatacc gctggacaat cctgtcagca ttccaggtac
      481 aggcccaagc aatgcaccag caaaaatcgt tccgatagaa tcgagataga ttggcaaacg
      541 aagccataaa gcaatcgttc ctccaatata attgatccca atacacaaag ccatcactgt
      601 aagtacgcga gttgccattt tgtttttatt cattttgtta gcccatcttt aacctttcca
      661 aatctttcat aatcgtttct tcttgtgcat ttaaaagaac ggttaaaaac tttcggaaaa
      721 aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc caaaattcat
      781 aacgatcaac caatgtttgt ccacgactta ttccttgagt ttccacagca gtgaagcttt
      841 tgaaaccttc acagatggcc tcctcgataa aataagcaac agctaacgga tcattgatga
      901 cacatcctaa aattctttct tgtttccagt ggaagtcaaa ataaaaacga gtgatcgctt
      961 ttagatactc tccctcttca ggattcattt gacagcagta ttcgaggata gtcggtgtca
     1021 agacgatttc tcttgtcaca tctaacccaa ccatttctat cgtttgtttg agattctcga
     1081 atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact ggcgaacagt
     1141 taccatggct tttgtaagtt ccacccatcg agacaaaacg ttccatatgt ttcccaatat
     1201 ttgggttgac tttcaaagca gaagcgatat tggtcaaagg acccaaagca atgactgatg
     1261 tatttgtctt ttctttgaaa taatcagcca aaaaatcaac ggcatggaga ggttctgcct
     1321 gttttctcaa gatcatcggg aaatttgttt cccctaaacc atccatacca tgagtgtctt
     1381 gtgcactgat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca ggaatgtcta
     1441 aacgatcaca gcgttccagg catttcagca cattctgcgt acctatatct gcagggacat
     1501 tcccacaaac tacggtaata gcaactactt cgatatcagg ggatttgaca gctaatgata
     1561 aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tacttttcgc attatttcca
     1621 atctcctttc tttagagata cttagttttt tattctggga agtttccgaa ccagtccaag
     1681 acgagcgtct tgattataat gcacgaaatt agtatactgg cttttattgc gaatgtaaat
     1741 gctctcttac aagtaaatct attgaggaga actttaagta aatgatacaa tgaaaaagaa
     1801 atggaattta cgtgtgccga aaataaagaa tcctatggat cggtacattg gataatagat
     1861 agattatagt ttggcagaaa gcggcgggtg tacaatggtt attttttatt tcattcttat
     1921 tctgataatt atagggatca gttaccattt tctttcttat ttttatgcaa agaaattagt
     1981 aagagcggga gtacagagag gatatgactg gtatgaagac actggtcatc gtttgatgga
     2041 ccctgctgca gtcacgtcag tagaaaaaaa acgacaaaaa ttagaagaag agtgtgaaag
     2101 cttttgggag cagggaacac ccaaaacaat caaaagttat gacgggttga aactagctgg
     2161 tcagatgttc atccatccaa ataagcagaa taaatgggtc atttgcgtac atgattaccg
     2221 aagcacaggg aaaagagaca tgtctcatat aggtaaaaga tatgcagaga aaggattcaa
     2281 cgttcttgta cctgatttac gtgcgcacgg agaaagtgaa ggagaaatca tcggaatggg
     2341 atggctagat cggctagatt taattgcctg gatccaactc atcttagatg aacagccgaa
     2401 tgcgtccatt attttacacg gcggatcaat gggagcttct acgatcatga tggcaagtgg
     2461 tgaaaaactt ccatcagcgg tcaaaggatt tattttagac agcggatatg tttctgttta
     2521 tgcagaattc cgatatatgt taagtaaaat cactgtcttt cctaaaaaaa tggtcatgag
     2581 atatgcgaat cattatgccc agaaatacgc cggttactcc ttaaagcaag catcagctac
     2641 gagacagctt ggcagcaatc atctgccttt attagtcatc catggtgaaa gagatcattt
     2701 tgtccctaca gaagcagcgt acacgattca aaatgctacg gcaggggata aagcactgct
     2761 gcttgttccg gaagcagaac acttggaagc atcgatgaaa gatccgaaaa cctattggac
     2821 agtgattttt tcatttattg aacaaagaat aacgatgaat taattttctc ttcttttttg
     2881 taagtaattc gaggataaat aattgtttat agatcaggag actgctaaaa taaggtagga
     2941 ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagaa gaaaaaatcg
     3001 tcttgcttta ttcaatgatg aacaacaaga gatcggagaa atgacatggt cagatgcggg
     3061 cccagacatc atgatcattg accatacatt tgtagatcca gcatatcgtg gtcaaaagtt
     3121 agctgaaaag ctagtgtata ctggagtaga attagcaaga cgagacggga aaaagatcat
     3181 tcctttatgc ccttatgcaa aaaaagagtt tgaaaagaaa ccagaatatc aagacgtctt
     3241 acgtcagtca taagaata
//
LOCUS       DAPBCF010000130         3070 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.138, whole genome shotgun sequence.
ACCESSION   DAPBCF010000130 DAPBCF010000000
VERSION     DAPBCF010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.138"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(334..696)
                     /locus_tag="RD508_002904"
     CDS             complement(334..696)
                     /locus_tag="RD508_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737411.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(770..1150)
                     /locus_tag="RD508_002905"
     CDS             complement(770..1150)
                     /locus_tag="RD508_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HDT7737412.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1214..2407
                     /locus_tag="RD508_002906"
     CDS             1214..2407
                     /locus_tag="RD508_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7737413.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2484..3068)
                     /locus_tag="RD508_002907"
     CDS             complement(2484..3068)
                     /locus_tag="RD508_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7737414.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          958 a          587 c          504 g         1021 t
ORIGIN      
        1 aacgactcag ttatcttatc atgtcgttag taacatgtca ataactattt tttaaatttt
       61 ttagaaatgt gatataacat ccacttcaga atcaacgctg ttaaatttat catgtatttc
      121 ttccttggtc aactataaat taagcattac tttgtgaaat gatttttcga tcaattatta
      181 ttattcgtta tacaaccgtt ttcaacatat tttgaaaata aaatgcacta aaaaactatc
      241 tttagcagaa catttcattg tattttttgg accaaacaat aaaaaaagaa gtttgaaaaa
      301 aattcaaact tctttgttcg cttaatctgt attttagaag aaaggcactc cctctacttc
      361 gtaagttcca agaacagagc gcatttgacc tggttcttcc caaatatatc cttcgcctaa
      421 ttcttctctt tgattctttt gttcagtttc aaagacaaac aacggaacat tttcctcttt
      481 aatatgtgta tttgtcaatt ccatcaaact aatcttgcta acatcgatat gaactatttc
      541 ttttaagaaa ttaagtatat tcgctaaacc agtctttcct tcagaaagtt ccgctaacgc
      601 aaattccaac ttgtcatcaa ttgaatggac caaaaatttt ttagtaccat cctccaaatg
      661 caacataatt gtaccagcaa ctcttttgct tgccaaaatt tccacctcga tcaacttgtt
      721 ctatggctta cataaaaatt ctagcacatt ttcagaaaaa atacactttt tatttcttat
      781 tttctttccg ttctagttca gataatgctt cttctatcca aataggtaac tgctccgcaa
      841 tagtggtaaa tccgatctta cgatttttat tcgtgaaata cctttttctg cgatatggaa
      901 cagctggatt tgttttttct aacgttctta aagataaact gatttttttg gaatattcat
      961 caatgtcgat gatctgaact gttactggct gtccgacttt taacaatgaa tggatatttt
     1021 tcgtataacc ggattgtact tctgaaacat gaataagtcc ttgcgtctcg ttatcaagag
     1081 aaacgaatgc gccataaggc tgtatccctg tcacttttcc ttcaattatt tgtccaattt
     1141 tataagtcat ctacttccct ctcttcgcat ttatcattat actgtaaata gctcaaaaaa
     1201 agaagcgacg aaaatgactg gaggtcttaa gatgatcgaa tttgataaac agatttcaag
     1261 aaaagataca gaaagtgtaa aatgggacgc aattgctgag acatatcaaa tggatgactt
     1321 acttcctttg tgggtagcag atatggactt cttgtctccc ggtggggtag ctaaagcgtt
     1381 tagtgaatac atcaaacatg gaatctttgg ttatgccact ctgtctgata aactatatca
     1441 ggctatcatt cattgggaac gccaacacca tgctgtggag ttgacgaaag aaaatatcgt
     1501 ttttacaagt ggtgtgttaa ccagtttagc tgcagcagta caaactttta caaaaccagg
     1561 cgattctatt ttgattcatg acccagttta tcctccattt tcctctatta tagaaacaaa
     1621 tcaacgtcac atcgttcgaa gctctttgct agaaaaaaat aatcatttca tcatggactt
     1681 gtctgacatg gagaaaaaaa tcgaagaaaa caatgtaaaa gcaatgattt tatgcaatcc
     1741 tcacaatcct ggagggcgtg tttggagcaa agaagaattg aaacagttaa gcgaattgtg
     1801 tttaaaacat caagtgattc tgtttagtga cgagatccat caagatttaa ctttattcga
     1861 tcatacattt acttccatgc taacgattga tcctaattta gatgatctac tagttgcttt
     1921 tacttccgca accaagactt tcaatctagc tgcaatcaaa aattcaatgg tatttatcaa
     1981 aaatccagag atgaaagctg attttgaaaa acatttagtg atgaaccaac agcacgaaat
     2041 caacactttt ggactgattg gaacccaagc ggcttatgag acgggtggag aatggttaag
     2101 ccaactgatt ccttatctag aaaaaaatgt tcaaacagtt aatcagtttt ttgaacagta
     2161 tcttccgaaa gtgagaataa tgaaccctga aggaacttac ttaatgtggt tagattttac
     2221 cgcctatatt tcagacgacc aagaattgga gaacactctt gttcggaaag gaaaagtcgt
     2281 attaaatcct ggcatcacgt ttggtccttc cggtcatggg catatgcgct tgaatattgc
     2341 ttgtccagaa gaaactttac tggaaggact taatcgaatc aagtatgctt tagagacaat
     2401 cgattaaatc atttattcaa aataaaagga cgagacctta ctaggtttcg tcctttttca
     2461 taattactcc gtaccatacc aaactattct gaaatttcaa ttgtttcaat cactacatca
     2521 tgtacaggtc ggtcttgtgg accacgttgt acatttgcga tttcatctac tgtgtccatc
     2581 ccttctagta catgtccaaa gactgtatgt cggaaatcta gccaaggagt tccgccacct
     2641 ttatacgctt caatgatttc tgatgggaat ccagcacctt ctagttgtcc aagcatatta
     2701 gctggcacat ttgtgttatt tacaataaag aattggcttc cgtttgtgtt tggacctgaa
     2761 tttgccatag ataaagctcc gcgaaggttg aacagttcac gactgaattc atcttcaaaa
     2821 ctttcgccat aaatactttc gccacccatt cctgttccag ttggatcgcc gccttggatc
     2881 atgaaatcag gaataacgcg gtgaaaaatc acgccatcat aataaccttt tttggaaagt
     2941 tcaatgaaat tttgaaccgt cttcggtgct agttcaggga ataattgaac agtaatgtca
     3001 ccacggtttg ttttgataac agcttttggt cctttttcac tttttaaatc tagttgtggg
     3061 aatgccatat
//
LOCUS       DAPBCF010000131         2970 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.139, whole genome shotgun sequence.
ACCESSION   DAPBCF010000131 DAPBCF010000000
VERSION     DAPBCF010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.139"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..363
                     /locus_tag="RD508_002908"
     CDS             <1..363
                     /locus_tag="RD508_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7737415.1"
                     /translation="RKKRDKQAAYAFLKRLIKQFGEPKVLVTDKAPSLSSAFNQLHSE
                     GLFSKTEHRTNKYLNNIIEQDHRSIKKRHKLYQSIRTASSTIKGIETIHALYKISQRD
                     KSLFGFSVIHEMNTLMSI"
     gene            411..869
                     /locus_tag="RD508_002909"
                     /pseudo
     CDS             411..869
                     /locus_tag="RD508_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628348.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            869..1759
                     /locus_tag="RD508_002910"
     CDS             869..1759
                     /locus_tag="RD508_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7737416.1"
                     /translation="MEELIRVEHATKTFRSKNWRGTVSEVRAVEDVSLTIHRGETLGL
                     VGESGSGKTTLGRSILNLETLTSGEIFFEGKELTALTAEDRKAAYQQMQIIFQDPYSS
                     LNPRMTALELVMEPLYHETKDAARAKAKEILAIVGITGDDVHKLPRSFSGGQRQRIGI
                     ARAVVNRPAFVLCDEPTSALDVSIQAQIIQLLLRLQKEFSLSYLFISHDLSVIRHISD
                     RTAVMYQGKLVELAPTDRLFDNPLHPYTKKLLAAAPIADPVLARGAMEQTEIQSTITL
                     TPLYEWVEVEPDHFVRREKR"
     gene            1756..2148
                     /locus_tag="RD508_002911"
     CDS             1756..2148
                     /locus_tag="RD508_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HDT7737417.1"
                     /translation="MTVETLTIHQGSDKLEMTTPTGNWVLAREKGYSPVQMLVSAVAA
                     CGGYVYASVLENSKITAEIEKIEVSYDRDDNKKAQPVSAIHIQFYAKIAEADHDKATR
                     CLKLVSPNCPVIQSLDPAIEVTETVTFI"
     gene            2334..2970
                     /locus_tag="RD508_002912"
                     /pseudo
     CDS             2334..2970
                     /locus_tag="RD508_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          943 a          598 c          653 g          776 t
ORIGIN      
        1 cgaaaaaagc gtgataaaca agcagcctat gctttcttaa aacgattgat caaacaattt
       61 ggagaaccta aagttcttgt cactgataaa gccccttcac taagtagtgc gtttaaccaa
      121 ttgcattctg aaggattatt ttctaagact gaacaccgaa caaataaata cttgaataat
      181 atcattgaac aggatcatcg atccatcaag aaaaggcaca aattatatca gtccataagg
      241 actgcttcct caacaattaa aggaattgaa accatacacg ctttatataa aattagccaa
      301 agagacaaaa gtctctttgg cttttcagtg attcatgaga tgaatacatt aatgagtatc
      361 taagcataaa atcaaaaatt aattggaaac tctttattaa ttttttaact ttgcaacaga
      421 acccccacga gttatcagga gggatgcgtc agcgggtgat gatcgccatg gctttattgg
      481 cgcaaccgaa attgctgatc gcagatgaac cgacgacggc tttagatgtg acgatccaag
      541 cacagatttt ggccttgatc aaaaacctgc aaagagagaa ccagctttcc gtcgtccttg
      601 tgacccatga ctttggggtc gttgcaggaa tgtgcgactt tattaaagtg atgtatcaag
      661 gtcgagtcgt ggaagaaggc accacggaag agatctttta tcaacctgcg catccttata
      721 cgaaacaatt attgcaagcg gcacatttag gcgacaagca tgccgaatta aaagtctttg
      781 actatcatga gacattggca aatgagttgc aagaaacgca gttatctaag acccatcgcg
      841 tttggtgcaa tcaggaggtg acagaataat ggaagaactg attcgcgtag aacatgcgac
      901 gaaaaccttt cgcagcaaaa actggcgcgg cactgtcagt gaagtccgag cggtcgaaga
      961 tgtcagtcta acgatccatc ggggcgagac attggggcta gtaggggaat ctgggagtgg
     1021 gaaaaccact ttaggacgca gtattttaaa tttagagact ttaacaagcg gagagatttt
     1081 ctttgaaggc aaagagctaa cagcattgac ggcagaagat cgcaaagcag cgtatcagca
     1141 aatgcagatc attttccaag atccgtattc atcattgaat ccccgcatga cggcacttga
     1201 actggtgatg gagccgttgt atcatgaaac gaaagatgct gcccgagcga aagccaaaga
     1261 aatcttagcg atcgtcggga tcacgggtga tgatgtccat aaactgcccc gcagtttcag
     1321 cggcggacaa cggcaacgga tcggcatcgc tcgtgcggtg gtcaatcgcc cggcgttcgt
     1381 cttgtgtgat gaaccgactt cggcattaga tgtctccatt caggctcaga tcatccaatt
     1441 gctgctgcgt ttgcaaaaag agttttcatt gtcttatttg ttcatttccc atgacttgtc
     1501 cgtgattcgt catatcagtg accgaacagc cgtcatgtat caagggaaac tagttgaatt
     1561 ggcacccacc gaccgtttgt ttgacaatcc gctgcatcct tacacgaaga aattattagc
     1621 agcagcgccg atcgctgatc ctgtgttagc aagaggtgcg atggaacaaa cggagattca
     1681 aagcacgatt actttgacac cattgtatga atgggtcgaa gttgaaccag atcattttgt
     1741 gaggagagaa aaacgatgac agtagaaaca ttgacgatcc atcaaggaag cgacaaactt
     1801 gaaatgacga ccccaactgg caattgggtg ttagcacggg aaaaaggcta ttcgccagtc
     1861 caaatgctgg tgagtgcggt cgctgcttgc ggtggctatg tatacgcatc cgtcttagag
     1921 aattcaaaaa tcacagcaga aatcgaaaag atcgaagtca gctatgaccg agacgacaac
     1981 aaaaaagccc aaccagtcag tgccatccac attcagtttt atgcgaaaat cgctgaagcc
     2041 gaccatgaca aagcgacccg ttgcctaaaa ctcgtttcac caaattgccc cgtgatccaa
     2101 tcattagatc cagcgatcga agtgacggaa acggtgacgt ttatttaatc gaaaaagact
     2161 ttgtgtgcct gaaaccaata ggcgtacaaa gtcttttggc tctataattt atgggactga
     2221 tgaatcagaa ttgattcttc agccccattt tcattttagg tattaaaaaa catatcgttc
     2281 tctagtatga ttaaatcacc acaaaataaa caactgagag gacgatatgc tatatgaatg
     2341 attctatcaa aaaaatgctg agaataatag agaaagattt gatgattaca gaggtctctt
     2401 acgagaccct tcagaagaaa aagacgttgg tcgtcgatgc tgttctctcg cctactcctc
     2461 gtgcttgtag aagttgtgat tctactgtgg tagatggaaa cgggaaagca attatggtga
     2521 aaaatgggaa gaaggaaacg attgtccgtt ttgaacaata aaatcatatg cctttggtta
     2581 tgcgcctaaa aaagcagcgc tatacctgta aaaactgtcg cacccattgg actgctcaaa
     2641 gttattttgt ccaacccaga cattcaatcg caaatcatgt tagatataaa attgcttctt
     2701 tactgactga aaaagtatct ttatctttta ttgcgaaaag ctgttaggta tctttgacca
     2761 ccgttattcg tacattgaaa gagtttaaaa gctatttacc aaagcaatct aagaagattc
     2821 tccccagagt attgatggtt gatgaatttc gttcgcatac ttctatagaa gataaaatga
     2881 gctttatttg tgcagatggc gaaacaggaa aattaataga tgttttgcct acgcgtaaat
     2941 tacctcgatt aacaagctat ttcttaggtt
//
LOCUS       DAPBCF010000132         2862 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.141, whole genome shotgun sequence.
ACCESSION   DAPBCF010000132 DAPBCF010000000
VERSION     DAPBCF010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.141"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..319)
                     /locus_tag="RD508_002913"
     CDS             complement(<1..319)
                     /locus_tag="RD508_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HDT7737418.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTK"
     gene            972..1067
                     /locus_tag="RD508_002914"
     CDS             972..1067
                     /locus_tag="RD508_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDT7737419.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(1369..1614)
                     /locus_tag="RD508_002915"
     CDS             complement(1369..1614)
                     /locus_tag="RD508_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737420.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1959..2240
                     /locus_tag="RD508_002916"
     CDS             1959..2240
                     /locus_tag="RD508_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737421.1"
                     /translation="MDILVRNINPKIITRIDKRCQELTTKTGKKWSRNQYLKILIEND
                     FDHELMNYKKDQFDLLFEKFIAIQAENTNILNDYVHTNNQLIETLIGGI"
     gene            2242..2658
                     /locus_tag="RD508_002917"
     CDS             2242..2658
                     /locus_tag="RD508_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737422.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
BASE COUNT          973 a          556 c          433 g          900 t
ORIGIN      
        1 tttttgtttt attgatttca aaaccagtaa acaaaacaaa gtagcgaata gaatcctcat
       61 cttcagtacg gtaagtaaga ttaagcatat ctttatagag cttttctaaa tcaccgacaa
      121 aggcttttgt agcagtcatc ttataatcac ttaactcttt taattcctcg aaagaaaatc
      181 taactttttt caaaccacga tctttcatac gagcgcataa tgcaaaaaat aaatccatct
      241 gcttagcatt gaaatttttc agcggtacta aattcaattc attttgatat ttgactgtta
      301 attccgtttt ttcatccatt cctttcttcc ccccttacaa ataaataata acctttaaca
      361 accaactcgt aaataggttg gttgttatta tacaaaagga tattagtact cagataaaaa
      421 gttgttagta ctcagataaa aagttgttag tactcagata aaaagttgtt agtactcaga
      481 taaaaagttg ttagtaccct tctgtatccg ttgggagagt aaggctcaac tgccccctaa
      541 aaagggttct aaaaaatctt taaaaaataa ataaaataaa cgcgcgcgcg cgagcaaaat
      601 ttcccgccaa aaaatcaccc actttttaaa ataaacaggt tcgcgcatga tattaaactg
      661 ccaatctagc tccctatggt cgctgtaaga aggagtgatc gctacgctct cacattttac
      721 ttgcagcagt cgcctttagg ctccttcgcc aaaaataatt cattagggac tcctttgtgg
      781 cgtcctgaga gctcgtctaa gccgttctaa gacaagattc gataaaaact atgtccttcg
      841 ttctaaagcg ccttacaggc ggtcagggca agccctaaca accccaaggc aataaaaaac
      901 ttaggcttat ttttgctttt ttattgtata attgattgtc gcctatccga cagtcttgcg
      961 actggaagga ggtgtgtttc gtgttcacta actttatttg ctcccttctt gttgggcttt
     1021 taagcgcttt gttcagttac tggttgaata accgaaacaa gaagtaaaac ttaattaagg
     1081 cgactcagcc cacaaaaaaa gccccagaga atccgacctc tctggggctt tcgtgtgttt
     1141 cgtgttcact tatttgcaat caaattataa cagaaataaa tatttatttc aaaaatatcc
     1201 tacaaaagtc taaaatccgt aattatttct tatatgcaac atttacaaat aaagtcgctc
     1261 tgagagctcg tatttttcga tttaagacgt tttatttagt ttttggtgta tttcattggt
     1321 ccaagctaaa aaactcttag aagcgatttt agagccattt aaacccactt aattatattc
     1381 tccatgaaat tcgctccatg cgtcaaaagc tgcgtctgaa attccgccgt cttcgttcac
     1441 tagttgcatt aatttttcca acgatcgttt tctttcgggt gtcatatttt tatattccaa
     1501 caatttttcg tctgttaaat cgaacttgat tgcttgaatt gcttgctcta atttttctaa
     1561 gttttgaaaa tattcgtaag gaaatttttc cattttttct ttctccagtc tcacaatttt
     1621 tctagaaata aaatcacttc tttgccgtct atactctcaa aaaaaatgtc gtttgaaaaa
     1681 ctaaataaat ttttgatcgt gcatttttaa atttggttat cgattacacg tgcagcactc
     1741 ccccccgaat tttaaagagc ataaggaaac gtggtatcac tttcttacga aaggtgctag
     1801 ataagctgtg cctatcacgt ttctcagaaa aaaatttgct atcacttttt tgccattgtg
     1861 gctaggctat gtatagtgtt ttggcgaaaa atagctatac aaatactata tttgtatgat
     1921 atacataaat tatacactga tacgaaagga aaatttccat ggacatttta gttcgaaata
     1981 tcaatcccaa aattattaca agaatagata aacgttgtca ggaactaaca accaaaacgg
     2041 gcaaaaaatg gagtcgaaat caatacctaa aaattttaat cgaaaacgat tttgaccacg
     2101 aacttatgaa ttacaaaaaa gatcaattcg atttattatt cgaaaaattt attgccattc
     2161 aagcagaaaa tacgaacata ctaaatgact atgttcacac aaacaaccaa ctcattgaaa
     2221 cacttatcgg aggaatataa catgagaaaa acttctgttc aaaaacacgt aaccctttat
     2281 cccagtcacg ttgacgtttt agattccatc atcgaaaaaa atccagacgt taacaattat
     2341 tcagaagcca ttcgcttttt atgtatgagt tatgaacctg ataccaatac aaccacaacc
     2401 agtaaccaag caaaactcaa tgccatggga aaagaaattt ctatcatgac agaaatcatg
     2461 gcagaatttg ctgatttata tctaaaagat actggtgttc ttatcggtac aaattctaaa
     2521 gtatatcaag aagtgaaaga aaaaattgaa aatcaactca atccttcccg acgaaatcaa
     2581 cccaaaaatc gtcaaaaaga aaccaatcaa acctttactt ctggaaattt tgacccaaca
     2641 aactttctaa aaagataaaa aaagaaaccg aaaaacaaaa aaattcctcg atttcttttt
     2701 agggatcggt cttccagcaa gatttgcaag ttggtaccaa cttgcgaaaa aaaagaagaa
     2761 ttcgcagaag cggatttttc ttttttcatt ttggggcgct gccctaatcc ctaagtcccg
     2821 gttattcaat agcatggaaa ctcaaagaat aggacgttcc ct
//
LOCUS       DAPBCF010000133         2719 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.142, whole genome shotgun sequence.
ACCESSION   DAPBCF010000133 DAPBCF010000000
VERSION     DAPBCF010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.142"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="RD508_002918"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="RD508_002918"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDT7737423.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         1065 a          420 c          556 g          678 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatca
//
LOCUS       DAPBCF010000134         2468 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.143, whole genome shotgun sequence.
ACCESSION   DAPBCF010000134 DAPBCF010000000
VERSION     DAPBCF010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.143"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            82..>2468
                     /gene="esp"
                     /locus_tag="RD508_002919"
     CDS             82..>2468
                     /gene="esp"
                     /locus_tag="RD508_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HDT7737424.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVS"
BASE COUNT          893 a          386 c          506 g          683 t
ORIGIN      
        1 tcctattctg tgaataatac gtatcagatt tatcttttat tcttactagg aaagtaatta
       61 ttaagggagt tgatttgaat aatggttagc aagaataata agagagtatt tctagaaaaa
      121 acaaagaaac gagtattgaa gtacagtatc aaaaaattaa gtgttggggt tgcatctgtt
      181 ttgattggtg ttggtcttgt cttgggaaca actgaactag ttaaagcaca agatgaaatt
      241 tctccaagca gcccacttga aacagcgata agctccgtac aagtaggtga caaagtagct
      301 tcggggaata cttttcagga gaatcctggt tatacgaaaa attataactt ttcggattta
      361 caatttagtc ctcaagaact aactggagac acactaaaag gcaatacaat tggatttgaa
      421 gtttacggaa aacataatat tgcagcatca actaaaaact gggaaatccg tcttcaatta
      481 gatgaacgat tagctaaata tgtagaaaaa attcaggtcg atccaaagaa aggaattgga
      541 tcttctagac ggacctttgt aagaattaat gattcgctgg gtagacctac aaatatttgg
      601 aaggtcaatt atattcgtgc aagtgatgga ttatttgctg gggcagaaac aaccgatacg
      661 caaaccgctc ctaatggggt aattacgttt gaaaagagcc tagatgaaat ttttaaagag
      721 ataggcatag acaatctcaa gaccgatcgt ttaatgtatc gaatctactt ggtaagtcat
      781 caagacgatg ataaaattgt accgggtatt gatagtacgg gctacttttt aacagattca
      841 gatgatttct ataatagctt agatgtatct gaaaataatc ctgaccagtt taaacatgga
      901 tcagtaagtg caaaatatga gaaacctaat actcaaacaa aagatggttc aggatccaca
      961 ggtgctaatg gagctataat cttagatcat aagttaacga aaaattataa tttctcatat
     1021 tcatcttccg caaagggcac gccttggtat gctaattaca aaattgatga acgattagtt
     1081 ccatatgtag cgggtataca gatgcacatg gttcaggctg acaaagtaac atatgatgtt
     1141 tcgtttgaat ccggaacaaa agtagctgat ttagcaatcg agcgacggga aggtcatgaa
     1201 aattatggca taggttcaat aactaataat gatttaacta aacttatcga ttttgctaat
     1261 gcaagtccac gtccagtcgt tattcgatat gttttacaat tgactaagcc attagatgaa
     1321 atcttagaag atatgaaagc aacagcacaa gttgaagaaa ataaaccatt tggtgaagat
     1381 ttcatctttg attcttggtt gtcggatacg aataaaaaat taatccagaa cacttatgga
     1441 acaggttatt attatttgca agatattgat ggtgatggaa accctgacga taaagaagag
     1501 agcggagaca cgaatccata tatcgggaaa cctgaattag aagaagtata tgatgttgac
     1561 acaacagtta aggggaaagt attcatccac gagttagcgg gaacaggtca caaagcccaa
     1621 cttgttgata aagaaggtac tgtattagca gaaaaaacta tcgctccaaa tgaaaaagat
     1681 ggggctccaa tttcagatac tgtagaattt gaatttacgg gtgtagattc aagtaaatta
     1741 atcgcgaaag atgaattaaa aatccaaatc gtttctccag gttttgataa accagaagaa
     1801 ggttcaaccg ttattaagga atcaccaaaa gcggttgata aacaaaccgt ggtagttgga
     1861 tttaaaccag atgctaaaga atcaattcgg aataataaaa acttacctga agatgcagag
     1921 tattcatgga aaacagagcc tgatacttct aacgttactg atagtacgaa aggtattgta
     1981 actgttaaga tcggaaatcg aactttcgac gtggatgtag agtttgctgt aaaagcttct
     2041 caagctatgg aaaatgatgc aacatacgta cctataacaa caactccaga aacgacagtt
     2101 caaagtggaa aacctacatt tgataaacca gatgttcctt tagctaaaga tgccttttca
     2161 atttcagatg tctataataa gtacttcggt aatgcaagtg ttgatgcaaa cactggtatt
     2221 gttacattca ctccagctaa aggtgtagga gaatcggagc cgattactgg aacaattcct
     2281 attaaaattg tttaccaaga tggttctgta ggcacgaccg atttagcagt aactgtaagt
     2341 aaagatattt atgaaaatcc aggagaaaac attcctgcag gctaccacaa agtaaccttc
     2401 accgcagggg aaggaacaag tattgaaagt ggaacaacag tctttgcagt gaaagacggc
     2461 gtaagctt
//
LOCUS       DAPBCF010000135         2406 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.144, whole genome shotgun sequence.
ACCESSION   DAPBCF010000135 DAPBCF010000000
VERSION     DAPBCF010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.144"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(51..643)
                     /locus_tag="RD508_002920"
                     /pseudo
     CDS             complement(51..643)
                     /locus_tag="RD508_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            881..1303
                     /locus_tag="RD508_002921"
     CDS             881..1303
                     /locus_tag="RD508_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737425.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTLADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            1313..1516
                     /locus_tag="RD508_002922"
     CDS             1313..1516
                     /locus_tag="RD508_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737426.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            1727..2311
                     /locus_tag="RD508_002923"
     CDS             1727..2311
                     /locus_tag="RD508_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7737427.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          803 a          367 c          417 g          819 t
ORIGIN      
        1 attgtagttt tagatatctg agaataaaga gagctgtttc cttaccatac ttacaaatcg
       61 ttttttattc tataaactgt ttgtctagtg atgttataat tttttgcagt ttttgaaata
      121 gcaataccct gatttagatc ctcaacgatg cttttataaa caaggcgacg ttggggatct
      181 tttgtgtctg cgctgtataa cttaggacgt cctttataaa caccatttgc ttttgcaatc
      241 ttaattcctt gtgcctggcg tcgtttagat tctgtacgtt cctgttcggc aatcatggcc
      301 aggatctgaa tgattaaatc cttgatgaac ttatccaaga gaggattgct tcagccatga
      361 ttggtaaact agtgatgata agttgtacat tttttctttt tagataatta accgattcaa
      421 tgatctcgtc ataatttctt ccaagtcgat cgatggcttc cacgataaaa atatcttgtt
      481 ctcagacaaa ttctaaagct tcttggaaaa ttggtcgatg agtaatcgtt gctccagatt
      541 gtttctcaat aaatattttt tctgcgccga acttcttcat ttcttcaagt tgcctttgtt
      601 cattttgatc aatcgacgaa actcgaatat aagcaatttt caaaaattta ccctactttc
      661 tcgaactatt taaaacacac cctaatcata cattagaaaa ctagatgtca cttttctttt
      721 taaatggcaa tattttttgt aaataaatgt caatcaagaa aatttaaacg attatgacat
      781 taaaaatata ttttatgaat tttctagtat ataacttgat ttatctgtta agatttatta
      841 agaaaacgtt ttcttatttt tgatttcgag gtgatagaca atgaaaaata agtttatttt
      901 atctttaggt attttaacta ttggaattag tgtaactgga actacaattc ctacacttgc
      961 tgatagtaca aatgaaccaa ctactgtagt agataataac caagaattaa ctcctttaga
     1021 taggaacgga atagccattg gtaacccaac taacgactta actgttactg aaaattattt
     1081 aatagtttct ccattacttg ctcgagcagc ttctaaaacg atacgagtga caggaacgat
     1141 gatttttgat aaagttggtt ggccttctag acctcctcaa tcacggaatt ggaaagaaaa
     1201 aagaaatggt tattggtact atggaaaatt gtatttacaa agttataaat cagctggaaa
     1261 caattggatt gcgacttatt caggaacctt aactagaaag tagggatttt ttatgccaga
     1321 atttgtgaac acaccaaatt tttatcaaga tagcgatatt ctaagtaaaa ttaatttacc
     1381 gaaagaagaa tcagctttac aagttcagcg aactttacag gagacacaaa aaattcaaaa
     1441 atcaatttct aatctagaag attctgaaga aaaaagaaaa aaaagagacc aaaaaacata
     1501 tcaaaaagaa aaataatgat tttaaaaaaa gagtgtctag tcgacattct ttttttctaa
     1561 ttgaaagtgt tcataaaatc acccatttct ggacactttc tttttttgct ttatttttca
     1621 aaaaaacaat tcatttcatg ttcataaacc cataacaata tctatgttca gttaaactat
     1681 atggataaag ttatgttaca ataaaattaa tgaaggagtg atttttttga aaataggata
     1741 cgcccgggta tctactggtt tacaaaattt ggatttacaa gaagacagcc taaataaatt
     1801 tggttgtgaa aaaattttta ctgatcatat gagtggggca aaaagtaatc gaccaggatt
     1861 agaaatggcc attgattttg ttcgctctgg cgatacactt gtcgtttggc gcttagatcg
     1921 tttaggtaga aatatggaag atttgatttc aatcgtcaat cgactgaatg agcgtggtgt
     1981 gagttttcat agtattcaag aaaatattac gatggacaaa tcaagttcta caggacagct
     2041 catgtttcat ttgtttgcgg catttgcaga atttgagcgt aatttgatcc tggaacgatc
     2101 cgcagcagga cgagcagctg ctcgtgcaag aggacggttt ggtggtcgtc ctgaaaaatt
     2161 gtctgaacaa gatttggaat tactgaagac tttagtggat agcggtacac ctattaagac
     2221 tattgcggaa cggtggaacg tctcaagaac caccatttat cgttatttgg caaaaatgga
     2281 ggagaaaaat ggaaagacaa attctcatta gtttttgtca tttaatgctg aaaatttttg
     2341 ccatttatct agaaaagtga caatagtatg agaatttttt gtaagtgtct actgataact
     2401 tattct
//
LOCUS       DAPBCF010000136         2396 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.145, whole genome shotgun sequence.
ACCESSION   DAPBCF010000136 DAPBCF010000000
VERSION     DAPBCF010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.145"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(139..1431)
                     /locus_tag="RD508_002924"
     CDS             complement(139..1431)
                     /locus_tag="RD508_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDT7737428.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVHTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1705..1965)
                     /locus_tag="RD508_002925"
     CDS             complement(1705..1965)
                     /locus_tag="RD508_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737429.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
     gene            2216..>2396
                     /locus_tag="RD508_002926"
     CDS             2216..>2396
                     /locus_tag="RD508_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7737430.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNG"
BASE COUNT          801 a          448 c          378 g          769 t
ORIGIN      
        1 atattataaa ttcacatgat tatcgaattt tattaagtta gtttttcttg taaatctctg
       61 ttcccaatga aactcgagac acttatttta aatagttaag agtttttaac caccataatt
      121 ctctcggcta ttttgaaatc agataaattt tgatcggaca catagttgaa taaacctacc
      181 gttgttacgg aaggtaaatc gcatactttt cattctagag gagaaggtct cgttgatcat
      241 taactgatta agcaccatag cccagttttg aattcgacca cctgaccact tcgcgtgtaa
      301 ttctttcgtg cgtaaataaa gtagttttag gagtgcattc tcattagaga acgctccttt
      361 ttttgtgact tttctgaagc tggagtggac actttcaacc gcattggtag tgtacataat
      421 ttttcgaatg gcactaccat aatcaaatag ttgttcaaca tgtgcaaagt tccgtttcca
      481 gacatctaca gcaccagaat aatgagacca ccgattttga aaactgtcaa aagcagcatg
      541 tgcagcgttt agagaagaag caccgtagaa ctttttcatg tctcgacaga cttccttata
      601 gtccttactt ggaatatagc gcaatgcatt tcgaacaaga tgaacaatac agcgctgaac
      661 aattaccgat ggaaagatcg cttttgcgcc ttcttcgagg ccagaaacac cgtccatcga
      721 aatgaaaaag acatcttcga caccacgtgc tttcagttca tcaaatactt gcatccagcg
      781 atttttagat tctgtttgat ttaaccataa tcctaaaatc tccttatttc ctttgagatc
      841 atagccaaga atggtgtgta cagcatattc tttggcttca taattttctc gtaaagtaac
      901 atacatacaa tcaacgaata gaaaggcata acactttgct agggggcggg cttgccattc
      961 ttccaattca ggaaggacag cgtcagtgat atctgaaatc atttcatggg aaatatcaaa
     1021 gccataaata gcttcgacgg ttgcggcaat atctcgttga ctcattcctc gtgcatacat
     1081 ggaaagaacc ttcccttcga tgtcggagac atctcgtttt ctcttaggaa ttaactctgg
     1141 ttcaaaggaa gcttcccggt ctctaggaac atcaatagct acttcaccaa aactggtttt
     1201 aagcgtttta gttccatagc catttcgacg gttatcgtgt tccttaggct ctttagaatg
     1261 ggcatcataa cctaaatgat tattcaattc tccttgaagc attttttcaa aaaggggccc
     1321 aaacacatct ttcaaagcat cttgcatgtc atcgacagat tcaggttgat aggcattcag
     1381 aatggattca gctaactttt cggcatcagg atttcttttc tttctagcca tcgtgtaatc
     1441 acctcttgat cttattgtag aaaaagaaaa accgcgaagc aaccacctgc ctaggattaa
     1501 tggttactta cacggtttat attacactct catcattaaa aaagtatctt tcgatattac
     1561 taaacaatga aattatctat ttgaaattta aatctgataa tatattgagt gttccaatga
     1621 gggctttgat cctattatcc atatcttttt cagttttaat attgatacac attataagaa
     1681 aaagaaactt ttggttaatt tatttcatcc cagtgcaaaa tataaaaaag taaaatagac
     1741 cataggcaat agattaacaa ttaatataat acaagcaaat attctattca ttgtatttct
     1801 gctttcaaaa agttctaata ttgaaagtat aattccacaa atgcctataa taagtatggg
     1861 aataagatta gaaaataaca ccccgagcca atctgtgaaa attactatat ttactaatat
     1921 ccctattaac atacctatca tatttattaa atcaattttt ttcattagat atttctcctt
     1981 tattaaatct gaagtactta tattaaaata attctaaact atttacctca aaaagtgcaa
     2041 taaattattt ctgaacaata aaatgatagt caaaacaaaa aaatattgtt aatcgttcag
     2101 agccatccga gagtgtaaaa tattttgtgt aaatgaaaaa atccatacaa aaaaggaagt
     2161 cgcttctgta gaataaagtt aacgacaacc aattcacaga aaagaggact tacctatgaa
     2221 tgattttact acagaaattg tgcaaactct agtcactaaa ggcgatttaa atgaattatt
     2281 ccgttcgcac ttagaaaaag cgataaacac actcctacgg actgaattaa cggctttttt
     2341 agattacgaa aaatatgatc gcactggttt taattcaggt aattcgagaa acggtt
//
LOCUS       DAPBCF010000137         2284 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.146, whole genome shotgun sequence.
ACCESSION   DAPBCF010000137 DAPBCF010000000
VERSION     DAPBCF010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.146"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            322..1620
                     /locus_tag="RD508_002927"
     CDS             322..1620
                     /locus_tag="RD508_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDT7737431.1"
                     /translation="MKHTHKIILAVTSVCTVIILGVSIFFVTQAATNNKLENTSQTTQ
                     HSSSSSKPVEDKQTTKQLDQAKQLAASYHYDEAIALLEKDDAKEAQQLLATLKKEKES
                     LVKWEDPTKISHVFFHSLIVDPAKAFHTQQAQGYKDYMVTISEFNKTIDQLYKNNYVL
                     VNLNGLVKKGTDGKLTFTGVSLPEGKKPLILSQDDVSYYEYMDNSGFPSKLIVDKQNQ
                     IKNIYIDNKKETVGDYDMVPLIDSFIKKHPDFSYQGAKGTLALTGYNGVLGYRTSKSE
                     YGDNEKTNKEIEAAKKVADQLKKDGWSFASHTWGHLNMTQASLADIQQDNERWQNEVA
                     PILGKTNILIYPFGADISDWQPYSEANQKFAYLKQQGFDIFCNVDASTPAWGQLGTDY
                     YRNARINIDGIRFEADLKGENPILDQFINVKEVYDQKDRG"
     gene            2133..2284
                     /locus_tag="RD508_002928"
                     /pseudo
     CDS             2133..2284
                     /locus_tag="RD508_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT          814 a          389 c          404 g          677 t
ORIGIN      
        1 tttttgttga tttaccaaca tgtttagaca ttttcctcta ggaaaaaatt aactagcatc
       61 acgggtttat tttagttttt cttggaaata aaaacagcga aaatccgaac attttcacct
      121 ctctcacttt ataactttta caaaatagta cttctcataa aaagcgctct agttaaagaa
      181 aataagagaa aaatcaaaaa aaacaaaagt ttcttttaca cttgtttcta tattcgttac
      241 aatggttatg ggaagttttt caaaaggtta agaaaagctt acgggggttt ttgaaatcaa
      301 aaagtagtag gggacgataa aatgaaacat acacacaaaa tcatattggc tgtcacttct
      361 gtatgcactg ttattattct aggtgtaagt atcttttttg ttacacaagc agcaacaaac
      421 aataaattag aaaacactag tcaaacaact caacactcaa gcagcagctc aaaacctgtt
      481 gaagataaac aaacgacgaa acagcttgat caagcaaaac agcttgctgc aagttatcat
      541 tatgatgaag ccatcgcctt acttgaaaaa gacgacgcca aagaagcgca acaattgtta
      601 gcaactttga aaaaagaaaa agaatccttg gtaaaatggg aagacccgac caaaatctca
      661 cacgtcttct ttcatagtct gatcgttgat ccagctaagg cttttcatac ccagcaagca
      721 caagggtata aagattatat ggtcactatt tccgaattca ataaaaccat tgatcagtta
      781 tataaaaata actatgttct tgttaatcta aatggattag tcaaaaaagg aacagatgga
      841 aaactgacct ttacaggtgt ttctcttcca gaaggaaaga aaccgttaat tctttcgcaa
      901 gacgatgtca gctattatga atacatggac aattcaggat ttccaagtaa gttgattgtc
      961 gataaacaga accaaatcaa gaatatttat atcgacaata agaaggaaac tgttggtgac
     1021 tatgatatgg ttccattgat cgattcattc attaaaaaac atcccgattt ttcttatcaa
     1081 ggcgccaaag gaacattagc tttaacaggc tataatggtg tattaggtta ccgtacatca
     1141 aaatcagaat atggtgataa cgaaaaaaca aacaaagaaa tcgaagcagc caaaaaagtt
     1201 gctgatcaat taaagaaaga tggttggagt tttgcttctc atacttgggg acacttgaat
     1261 atgacacaag cttctttagc cgatatccaa caagataatg aacgttggca aaatgaagtt
     1321 gcacctattt taggcaaaac aaatattttg atctacccat ttggcgctga catcagcgat
     1381 tggcaacctt attctgaagc aaatcaaaaa tttgcttact tgaaacaaca aggatttgat
     1441 atcttctgca atgtcgatgc ctcaactcct gcatggggac aactaggaac tgactactac
     1501 cgtaacgcca gaatcaatat tgacggtatc cgtttcgaag ctgacctaaa aggagaaaat
     1561 ccaatacttg atcaatttat caacgtcaaa gaagtgtatg accaaaaaga tcgaggatag
     1621 aggttgtgaa agaagcgtcc agctccgagc aaataagaac tagatttcta aaatagtttc
     1681 tcatattttg gaaatctagc gcttattgct gaggagttgc ttcttgaaca ccgtgaatag
     1741 aggttgtaaa aaaaccgttt tgacctgacg ataaccagta aaacagaggt gagaccattg
     1801 ctaaaagtag cagtggtctc atctcttttt ttgcacaagt catatttgat tgtttcgtta
     1861 ttttaatcag gataaagttc ttttttttca tgctaaagag tgattctttc ttctcgattt
     1921 tcactttctt cgtttaactt ttggtaaata cttctgtcag aaaaagctct aggtagacac
     1981 acgaaagcag ataaaaagcc taacttttgc aacagtttat gctgtcgttc aaagttaggc
     2041 ttttacagtt tataaatagg gttctgttgc aaagttttcc aaaaaatcta ttttagtgta
     2101 aaattgagaa aaaagacaga gaggacagag taatgaatca ttttaaaggc aaacaattca
     2161 aaaaagacgt cattattgtc gctgttggtt actacctgcg ttacaatcta agctatcgtt
     2221 aagttcagga attgttatat gatcgtggaa taaatgtttg tcatactacg atttatcgtt
     2281 gggt
//
LOCUS       DAPBCF010000138         2220 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.147, whole genome shotgun sequence.
ACCESSION   DAPBCF010000138 DAPBCF010000000
VERSION     DAPBCF010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.147"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(51..1598)
                     /locus_tag="RD508_002929"
     CDS             complement(51..1598)
                     /locus_tag="RD508_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDT7737432.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="RD508_002930"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="RD508_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDT7737433.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..>2220)
                     /locus_tag="RD508_002931"
     CDS             complement(2043..>2220)
                     /locus_tag="RD508_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737434.1"
                     /translation="IVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIYNGINNY
                     ILQAILKELLSNAL"
BASE COUNT          622 a          465 c          397 g          736 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
//
LOCUS       DAPBCF010000139         2180 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.148, whole genome shotgun sequence.
ACCESSION   DAPBCF010000139 DAPBCF010000000
VERSION     DAPBCF010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2180
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.148"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            135..308
                     /locus_tag="RD508_002932"
     CDS             135..308
                     /locus_tag="RD508_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737435.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            948..1421
                     /locus_tag="RD508_002933"
     CDS             948..1421
                     /locus_tag="RD508_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDT7737436.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1430..1657
                     /locus_tag="RD508_002934"
     CDS             1430..1657
                     /locus_tag="RD508_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7737437.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          707 a          345 c          321 g          807 t
ORIGIN      
        1 tttcggagaa ttaaaaaata caataaataa ctttagttac tttaatgcgt tcttacttta
       61 tttttatatt atcatttttc ttattcactt ctttggttta tactattctt ataaataaaa
      121 acgaggtatg tcctatgatg aaaagattgt actattcatt gatcataacg attggctatt
      181 tgattgtatc aaatctagga aatatggtat ttggtatcag taaagaattc agttggacta
      241 ctacattatg ggaatctcta ttctttttca tcttcgtatt tttgttacaa aattatcgaa
      301 aaaaataaac atgtgccatc tatctgttgg cacatgtttt aggatttatg gtacttttta
      361 ttcggcaatc cattttattt ttctacttct tcttaatacc tctaacactt ttgatttata
      421 aactaatcca atgcatctac ttgcgcttat taagctattt cagctagata gtaccacccc
      481 atgcgtcaat gcttgatttt ccttttgtat aacattgtat aagcaataaa ggacaaataa
      541 gtggtgatta caccaaacca ttgaataaga aaaattctga tacgtaaata aacatgaact
      601 tgaaaaaatt aatgaatcgg ttagctacta cgtagttgtc ttttttctca tacagttctg
      661 ttaacttaca cttctcttcg ctagataata aaaaatcctc caactgtatt gtccaatata
      721 atcccaggca tctaaactag cattatagaa gagacacaca tagaatctaa aataactggt
      781 tttaaatgtt tcttacaatc aaaaaaagct gttaaatgca ctccacacct tcatactcta
      841 tcatttttta taaacgatat atttttattg tttttcgata aaaaatagtt gttttacaat
      901 aattattctg ctatatttta gctatcaaag ataaaagagg gataaaaatg aaatttaaaa
      961 cattgctatt aaaatttgtc gttttaggta taagtgccgt atttattttg ttcggcgtac
     1021 ttttttatac tcagatcgct acaagcgaaa aaggattcaa ttttgattgg cagaccacat
     1081 tatttgtttc tgtcatttac tttgcccttc tcctagggat cgttattgct tatttcttat
     1141 tgaaactatt gaaaaaaatc gaagataacc aagctttttc cactcaaagc ttaaacatac
     1201 taaaaaaaat cgaacgaacc attttgttta ttggtttcgc cttttttggc ttacttccta
     1261 aatttatgaa agtagcggat ttagacgatg ctccaggttt gatgttggta ggaatcgctg
     1321 tcgtattcat tccttttgca gtatacacat taacaagcgt gctggaaaaa ctgcttgaac
     1381 atgcgatttt acttaagaca gatcatgatt tgacagtgtg aggtgcgaca tggcaattat
     1441 cgttaattta gatgtagtat tagctcaaaa aaaaatgagt gtgactgaat tgagtgagaa
     1501 agtgggcatt acgatggcaa acatctctat tctaaaaaat ggaaaagcaa aagccatccg
     1561 tttttccact ctcgaaaaaa tctgccaagt tttggagtgt caaccaggtg atttgttgac
     1621 ctataaaaat gactcgaata ctataccaga agaataaaat aaagtagaac aaacagtaaa
     1681 taaaaaataa tctgaatgat agatgtgtga gacttttaga agttatttac gtctattatt
     1741 cagatttttt atttcgattg aataccgttt tatctataaa taagatatgt actgactcat
     1801 acaaaggggg ccttttcttc tccatgtact atcacttttc ctgatacaac tggtttcctg
     1861 ttacgttgta gttggatctg cttttagtat aatactttat tcattccacc agactgatag
     1921 cagtttgagc agtctaaata atcatgtagt attacaggcc attctgtttc ataccttgaa
     1981 gtgcttaaaa cttcagctaa tggcccattg tgttaactct tactccattc ttttttagta
     2041 agctcccata tatactgtaa agccttctat atattatgtc atgttgcttt ttaacattta
     2101 ctatgtagtt ttgataaaat gatttgaata acagtgatgg acaattcttt tttattttta
     2161 acattatttt gataataatg
//
LOCUS       DAPBCF010000140         2056 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.149, whole genome shotgun sequence.
ACCESSION   DAPBCF010000140 DAPBCF010000000
VERSION     DAPBCF010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.149"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            493..714
                     /locus_tag="RD508_002935"
     CDS             493..714
                     /locus_tag="RD508_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737438.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="RD508_002936"
     CDS             715..972
                     /locus_tag="RD508_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737439.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKAAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="RD508_002937"
     CDS             complement(1108..1710)
                     /locus_tag="RD508_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HDT7737440.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKIRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="RD508_002938"
     CDS             complement(1777..1932)
                     /locus_tag="RD508_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7737441.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          464 c          313 g          601 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggcggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaat cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatca ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DAPBCF010000141         1995 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.150, whole genome shotgun sequence.
ACCESSION   DAPBCF010000141 DAPBCF010000000
VERSION     DAPBCF010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.150"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..741)
                     /locus_tag="RD508_002939"
     CDS             complement(<1..741)
                     /locus_tag="RD508_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HDT7737442.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGICYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEA"
     gene            complement(745..1803)
                     /locus_tag="RD508_002940"
     CDS             complement(745..1803)
                     /locus_tag="RD508_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDT7737443.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT          641 a          425 c          328 g          601 t
ORIGIN      
        1 agcttcatta tcttgaagct ctccacgggc tgtattgatc aagatgctgc cttttttcat
       61 ttgagctaaa aatccttcat tgatcatttg atcgttttca cctgggatat gaggtacatg
      121 aatactgacg atatcgcttt tggctaataa ctcttcaagc gagtggaacg tcaatacttt
      181 tttagcagct tctgtctgat gaatatcgta gccgataact ttggctccta gtcccttaaa
      241 caaaacagct tccgtcaacc ctatcctgcc tgttcctatg atccctactg tgcaatttct
      301 gatttcacga ctaaacattt gctcatccac tcgaaaatct ttgaaagatg ttcggatcgt
      361 cgtatacgca gtatttctca aaagcatcat ggcaaaagtc aaagataact ctgctatcgc
      421 atttggcgaa tacgatggta cacgggctac tgtcatacca aaatcagctg ccgcttgtag
      481 atcgatatga ttgactccca cagtccgtgt aaaaacataa caaatcccat attcctgcat
      541 ttttgcaaga ttggtctcat ctgctataca atttcccctc aacaatacag catcatggtc
      601 ctttgctgac acgatattgt catgtgtcaa cagttcttca taaagactga gatcataatg
      661 gtaaatattc aatttttcaa aaaaatctat ctcgttcgga cgaacaccgt aacatgcgat
      721 tctcatactt tcttcctcca tttcttatga aaataaacct atgccatgaa tcatttgtaa
      781 tacaacgatc catacaggtg tcagtaccac agcaaaaata gttgacagta aggatgcatt
      841 ggaggctaaa agtgcctccc tatcaaaact gatagcatag gctgctgcca ctgttgcagc
      901 tggtgtagcc atcatgataa cgattgttgc cagtgcttca aaattgactg gtagaatatt
      961 cgttgccgtc aaaactgcta gaatcacgat attcaatgca ggtacaaata ccactttgac
     1021 tagactgtaa taccatgaag ttttttcaga tgcagctttt ttgaagctta cttcacctaa
     1081 tgttgcgccg attgctagcc acgccaatgg tgaacttaaa ccagctaaat aatccatcgg
     1141 ctgaaatagc cacggtgcag tctggtcaat tcgcaaaaac gctacttggc ttatctctcc
     1201 ttctgcacct gtaactgaca cttgtggcag atacccttgg aacagccaaa tgaaaaggcc
     1261 ggcaaaagta gcgataatga ttggattgac gaacatcgct ttgatatttt tagcttccat
     1321 cttcaagcca ctcattttta tgtatccata agaatacaaa aagattcggt agccaatatt
     1381 gaaaattgag gaatacatca cgccgacagg accataaatc gcactgacga taggcgttcc
     1441 gaaaaaggtc gtagaaccaa agatcgtcag gacacgcaac gttgtttgct tatccccttt
     1501 atagcttaag aaaaaaggtt ttgaaactag aataagaata atataaataa ctaatcccca
     1561 aatcaagaca ttgattcctt gcatcagtaa ttctgtattg atatcttgca tgaaagctcg
     1621 aaatgccagt gctggcaaag ccactgttaa gacgactttc gatagaattt ttccaacaga
     1681 ttcagaaaaa atcccctttt ttctacaaac aaaccctaat aatataataa aaactgttga
     1741 agtgattgca ctgacaatcg acatatctgt caaagtcgat cgaaaaatgt caaataagtt
     1801 catctttctc ctcctaatta tgttcattta ttcacaataa aaaaacgctt ttattttgct
     1861 aatacgtatt aacattttta attttatctt tacattgtta cttattgaac aataggaaat
     1921 taaagaaact tttgaaactt atgtaaagtg atttttacta gaacacaaaa aaaaccttaa
     1981 aaccaaactt aagaa
//
LOCUS       DAPBCF010000142         1994 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.151, whole genome shotgun sequence.
ACCESSION   DAPBCF010000142 DAPBCF010000000
VERSION     DAPBCF010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.151"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            129..1853
                     /locus_tag="RD508_002941"
     CDS             129..1853
                     /locus_tag="RD508_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDT7737444.1"
                     /translation="MKKKLLTLFLVMSFSIVLSVYYNTIVFSEQINYTEEQYNIEKEK
                     ALKVGYSEEQFKQIMEIPTNLSNENSETRIVNYTMTSNQTKVINKAMEQIGKPYEWGA
                     SGPNSFDCGGLVKYVYKQAVNIELPMGTTNQEQYGTEVSLNSLKPGDLLFYGNRGATY
                     HVGIYKGNGVMIHAPQPGETVKEVNIQYFYPNFAKRILPDEPDYPYIDYNKMVTVTKA
                     WSIWNDLQFSHEIKKAIIGDNYKIGKVYTNPENNNKYGEILVSNKVYGYINFYAVKEL
                     TSVQINRYLTSKDSGQPTWGNLECTISKGQTTKDKIYFVKGAYNLGDGKYLYSIYKDQ
                     DSSEWLGYLKAHVSLAYTPIEEINKNVTVTKNWSIWNNLQWEKEIEKPQIGSVFSARL
                     KLTNVSNNAVYYKLYKSGKFYGYINAEAVKDLTTTKLNKYVTFSVNNEDFWSSLDVNY
                     SKGKTERGRVFYISISYNTADNQPIYSVYTDETCTEWRGYYKGNNFEDTQITMLENKS
                     VKVTKSGYTVWGDLNFWTKSGISNTGDIYTTDRKFYNFTNNAYYYELKKDGRVYGYIN
                     SEAAVEMN"
BASE COUNT          781 a          242 c          348 g          623 t
ORIGIN      
        1 tcagtttgta acaaacatat attttttata ttacaatatt tcaacaaatt aaaaaaaatt
       61 atatcttctt aaacaatgat aatattaaaa tgcaagcgct tgtaaaaaat aaggagaaga
      121 ggtaaaaaat gaagaaaaaa ctattaactt tatttcttgt gatgtctttc tcaatcgttt
      181 tgagtgtgta ctacaatact attgtttttt cagaacaaat aaactacaca gaagaacagt
      241 ataatataga aaaagaaaaa gctttaaaag ttggttatag tgaagaacag tttaagcaga
      301 ttatggaaat acctacaaat ttatcaaatg aaaatagtga aacaagaata gtaaattata
      361 ctatgacttc taatcaaacc aaagtcatta ataaagcaat ggagcaaatt ggaaagccat
      421 acgaatgggg agcatcggga ccaaattctt ttgactgtgg tggtttagtg aaatatgttt
      481 acaaacaagc tgtaaatatt gaactgccta tgggaaccac caatcaagag caatacggta
      541 cagaggtaag tttaaattca cttaagcctg gtgatttatt attttacggc aatcgaggtg
      601 caacttatca tgtaggtata tataaaggta acggtgtaat gattcatgca ccgcaacctg
      661 gagaaactgt aaaagaggtt aacatacaat atttttatcc taactttgca aaaagaattt
      721 tgcctgatga acctgactac ccttatattg actataataa aatggtaact gttacaaaag
      781 cttggtcaat atggaatgat ttacaattta gtcatgaaat taagaaagct attattggag
      841 ataattacaa gatagggaag gtttatacta atccagaaaa taataataaa tatggagaaa
      901 tattagtaag taataaagta tatggataca ttaattttta tgctgttaaa gagttgacct
      961 ctgttcaaat aaacagatat ttaacttcta aagatagtgg tcaaccaact tggggaaatc
     1021 tagagtgtac tataagtaaa ggacaaacta caaaagataa aatatatttt gttaaaggag
     1081 catataattt aggggatgga aagtatctat attctattta taaagatcag gattcctctg
     1141 aatggttagg gtatttaaaa gcacatgtta gtttagccta tactcctatt gaagaaatta
     1201 ataaaaacgt aactgttact aaaaattggt cgatttggaa taatctacaa tgggaaaagg
     1261 aaattgaaaa gcctcagatt ggttctgtat tttcagctag attaaagtta accaatgtat
     1321 cgaataatgc tgtctattac aagctttata aatctggaaa attttatggt tatatcaatg
     1381 ctgaggctgt caaagacctt acaacaacaa agcttaataa gtatgttaca tttagtgtta
     1441 ataatgaaga tttttggtct tctttagatg taaattattc aaaaggaaaa actgaaagag
     1501 gccgagtatt ttacattagt atttcatata ataccgcaga taaccaaccg atttattcag
     1561 tatatacaga tgaaacatgt acggaatggc gagggtatta taagggaaac aactttgaag
     1621 acactcaaat tactatgctt gagaataaaa gcgtgaaagt aacaaaaagt gggtatacag
     1681 tatggggaga cttgaatttt tggactaagt caggaatatc gaacacagga gatatataca
     1741 ccactgaccg aaaattttat aattttacca acaatgctta ctattatgaa ttgaaaaaag
     1801 atgggagggt ctatggctat ataaatagtg aagcagctgt agagatgaac taaaatattg
     1861 ctgtccctta atcttatggg gcagcaatat ttttatatta ttaatcattt ttctgaagcg
     1921 agggtagaag aattaatcaa tagtttttct tgttttgtaa tataatagtt taattaccaa
     1981 aaattattta agta
//
LOCUS       DAPBCF010000143         1933 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.152, whole genome shotgun sequence.
ACCESSION   DAPBCF010000143 DAPBCF010000000
VERSION     DAPBCF010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.152"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..567
                     /locus_tag="RD508_002942"
     CDS             <1..567
                     /locus_tag="RD508_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737445.1"
                     /translation="KIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGVNGAKFSV
                     YDVSDILQKMDVKNLTTDQIESQLKDRVKKLSGDQLKLVSNGETKTIDQQTGVFEFSI
                     EVQANQKQAYYIVNESSPENISNSEDILLLTPVSEKNGEFLKDVWIYPKSEASQPKEE
                     VKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            580..840
                     /locus_tag="RD508_002943"
     CDS             580..840
                     /locus_tag="RD508_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737446.1"
                     /translation="MKLIKLLLFNLSCLTAVFLYCGLLFSQLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            837..>1933
                     /locus_tag="RD508_002944"
     CDS             837..>1933
                     /locus_tag="RD508_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7737447.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRQDAVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVND"
BASE COUNT          688 a          319 c          358 g          568 t
ORIGIN      
        1 aaaattgctg aagacgatca aatagtcaaa cagaccattc acgttcaaaa gattatttct
       61 tccgaacaat tagacaacca ggggcaaaag cttgaaaaac aagaaggagt aaatggcgcg
      121 aagttttctg tttatgatgt atcggacatt ttacaaaaga tggatgttaa gaatctcact
      181 actgatcaaa ttgaatccca attgaaagat cgagtgaaaa aactatccgg tgatcaattg
      241 aagctagttt ctaatggaga aacaaagaca attgatcaac aaacaggtgt ctttgaattc
      301 tcgatagaag tacaggcaaa tcagaaacaa gcttattata ttgtcaatga gtcaagtcct
      361 gaaaacattt ctaatagcga ggatattttg ctattaacac ctgtttctga aaaaaacggt
      421 gaattcttaa aggatgtgtg gatttatcct aaatcagaag cttcgcaacc taaagaagaa
      481 gtaaaaaaaa tcgtttctac tggtgtaaag aaaaacttct ttgagaattg ttgggatttt
      541 gttactcact tgttttctag agattaagga agaaataaga tgaaactgat caaattatta
      601 ttattcaatc tttcttgttt aaccgcagtc tttttgtact gcggtttatt attttctcaa
      661 ttatctattt tgccaagcta ccaactatac ctaatgagga ttttaaacat accagctgct
      721 tccatgccgc tagatattat ggaaaagctc attaggaatc cattatttac tacgatcaat
      781 ttgatcgtta ttgtcggaat ttcactagtc atttataaaa aagaggggat gaagggatga
      841 attttaaaca ctcgtggacc agacggttaa aatatgtttt tcccataatg atgatgttag
      901 gtacattgtt tgggttaaaa acagccaatg tctttgctga aaaagttatt gtcgatccgt
      961 caaatccaat ccagaacgta aagaataatt ttattattcc aaaagatgtt cctaatgcaa
     1021 aaacaaatat tactgtaaac ggagcgtcca aagtttacaa atatcatgtt gatgccaaca
     1081 aaggtggttt tacagacgac tacgtaggat tagtggaggg aaacaaaaat atacgctatc
     1141 cttctttcca aaaggaatac ggtgaaacaa accttgtttt agaaggcgta acaaccaaca
     1201 ccaaagtcaa tattgactat ggaaaaatcg gtacgtataa cgggaaaaaa gtcaatatca
     1261 agctagttct atctaatatt cacttatact cggatacgtt gccgtggaat ctactagata
     1321 acaactatac aaaaactcat tttcgagacg atggctataa aaatacgaat ggtgcaatga
     1381 gtaaatctaa aaaaagaaca gtactttgga tctcagacaa tcttttctca ggaattgttt
     1441 accattcaac acaaatgaat gtgcagctag tagccacata tgaggacggt agccccgttc
     1501 aattttcagg agatacattt atcagtttta actctttgaa ccctgcagga ggaaaaagca
     1561 cggatcttaa aggagaatat gcccactatg acaaaatgaa tacgacagat tggtatgtca
     1621 gacaagatgc ggttctttca gaatttaaat ctttctacaa caatctgaac gtggtaggtg
     1681 gccacccagg aggaagctct aagctgacac aagcggataa tgatttcaat aatttgcatg
     1741 ataaattagg agatccgaag tttggtcaag gtactgtatc ctttaaaata tctgaagcaa
     1801 atccgacgtt tgtgattggt tcttctaatg ttcaaacctg gtttacttta tcttctgcga
     1861 caatctttag tgttgttcct gatcaacctg aaaaaacagg ggttgataaa aatggaaata
     1921 acgtgaacga taa
//
LOCUS       DAPBCF010000144         1884 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.153, whole genome shotgun sequence.
ACCESSION   DAPBCF010000144 DAPBCF010000000
VERSION     DAPBCF010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.153"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..455
                     /locus_tag="RD508_002945"
     CDS             <1..455
                     /locus_tag="RD508_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737448.1"
                     /translation="GAELLRLETEKYIMNVYLERSELVENFVSYMICRKHYYSESEYY
                     SIFESMELMEELNSKDATVDDYYLVFTKFLTCGTESIVLMGMDYELAVPEVFLREYVE
                     EVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRKRMPYQRFERKKGQ"
     gene            836..1015
                     /locus_tag="RD508_002946"
                     /pseudo
     CDS             836..1015
                     /locus_tag="RD508_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1077..1261
                     /locus_tag="RD508_002947"
                     /pseudo
     CDS             1077..1261
                     /locus_tag="RD508_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358324.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            1295..1726
                     /locus_tag="RD508_002948"
     CDS             1295..1726
                     /locus_tag="RD508_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HDT7737449.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
BASE COUNT          647 a          297 c          392 g          548 t
ORIGIN      
        1 aaggagcgga gcttctacga ctagaaacag aaaaatatat catgaatgtt tacctagaaa
       61 ggagtgaact ggtcgaaaac tttgtcagct acatgatttg caggaaacac tattactcag
      121 aatcagaata ttattcaatt tttgagagca tggaattaat ggaagagcta aacagcaaag
      181 atgcgacggt agacgattat taccttgtat ttactaaatt tttgacgtgt gggacggaat
      241 ctatcgtgtt aatgggaatg gattatgaac tcgctgtacc cgaagtattt ttgagggaat
      301 atgtagaaga agtagataac ccaggcgacg actggtacac gactttaact gattttttag
      361 atacctacac ttacgacgat acagaagaaa tccaaaatga acttgaccgt aaacgaatgc
      421 catatcaacg atttgaaagg aaaaaaggtc aataaccatt tataccgaaa agtgagaatg
      481 tgtgaaataa gaacaaaaaa ccttgaaatt aagggaatgg ttcttatttc gcaccaatcg
      541 ctccaaccgc ccccgccgct taggtggtgc gaaataagcg agcaaagccc gaaaacctaa
      601 gagaaagaag gagatttata tgaacaaaat tattccctta ttattagtcc tatttgttgg
      661 agaaatactt atgcgactta gtgcagctgt acatttaaac ctcgcagtat ttttggtaat
      721 actaatgttt tgtttgatct tttggcgatt tgtattagcc ctcgtaagtc tactattcaa
      781 gatgattgca gccatatttt tcataggatt atttcgatga aaggagagag taccaatgcc
      841 aattgcaata ggaaataaac ggttacccgt gacgttggat gaaaagagac aaaaagaatt
      901 gcagtaacca aagcagaagt acggcaaaag tgaatccagg attatgtgta ttgcgttaga
      961 tttattgatt gcgcaagaaa aagcaggatt tgacatacca gcactcaaaa agtgatcgca
     1021 ctttgcgcac gtgttaatac gtgttataat tattttgtaa ggaggtatag tgcacaatgc
     1081 cacttacggg aaaagaaatg cttaagttat tgaaaaaaat ggctgggttg agcgaaggca
     1141 agagggattt catcatcatc tttataagga tggtgttaga atcactgttc ctgttcatgc
     1201 caatcaagat cttggccgag gacttgagcg aaaaatttta aaggatgcgg gattgaaata
     1261 atctcgcatt cgattaaaga aaggattgac tgaaatgtta agtgagcctt tagcaaaaac
     1321 ctatcctgct atttttagcc cagaagaagg tggtgggtac tttattgaat ttcctgatgt
     1381 tcaaggtgct tacacaggaa ttaacgaaga cgatatatct tatggaattg ctatggcaca
     1441 agaggtgtta ggtatggttt tagcagatta tattgagcat gaagatctac ttccagaacc
     1501 aacaccaatc aataagattt ctgttgaaga tgattctttt actactttaa ttcgtgtaga
     1561 tgttgccaaa tatttgaaag acacagaact tgtcaaaaaa accttaacaa ttcctcaatg
     1621 ggcggataag ctaggcaaaa gggctggcat aaatttttca gtccttctaa cagaatcaat
     1681 tgcagataaa gcagataaca ttcttcgttc tggaagaaat aattagaact caaaagggtc
     1741 agaaacttaa aaatctttgg cttctttttt tactacaaag atggcttctt taaattattt
     1801 gcctgattga tttaaaaaaa ttgcgcaaag actacgagct aattaagttg ctcgtggtct
     1861 ttttttatga aaacttttta gatc
//
LOCUS       DAPBCF010000145         1709 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.154, whole genome shotgun sequence.
ACCESSION   DAPBCF010000145 DAPBCF010000000
VERSION     DAPBCF010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1709
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.154"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(111..518)
                     /locus_tag="RD508_002949"
     CDS             complement(111..518)
                     /locus_tag="RD508_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737450.1"
                     /translation="MPKDFDIPKMMENGEFEPLLPNNKRQDVKISGEYNFSNSALSNT
                     RNITLKKRGRPVSIPDKRNKVSVPKKISPALNSKLSILQDYMTELQSEKGRISFEKIV
                     NTLADSYIQHRLGVAKEEHIREEIQEEFEKLPK"
     gene            complement(537..1355)
                     /locus_tag="RD508_002950"
     CDS             complement(537..1355)
                     /locus_tag="RD508_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDT7737451.1"
                     /translation="MDTFQGTTFTVGNFKGGVGKTKIVSMLAYDNAMIRNRKTLIIDL
                     DPQANLTQVIARTFGITDIKTTITNGVANGELASSIIKVNENLDLLACDTSFRSFSAF
                     ANKHENELDQVTVLKKLLLPIKNNYQEIFIDVPPTISEFSDNAMAASDYSIISFQTAE
                     ESLEGVNKYVNYQKFMVDRYDLDLQIIDIVPCMVEPNDDFDEEILEEAIEKYGTVVSK
                     NLIHYQKRLRRYSKIGIHLRKYKNGNFDQWDYKAHQVFINILAELDARQEFLNK"
BASE COUNT          515 a          272 c          227 g          695 t
ORIGIN      
        1 tacacgttgt ttattaagtt ataccttaaa tatttaatgt ataacttata ctttaatatt
       61 catttatcta gtataactta tactttaatt gaataccgca tgaaaaaaaa ttattttggt
      121 aatttttcaa actcttcttg tatttcttct cttatgtgtt cttcttttgc tactcctagt
      181 ctatgctgga tatatgagtc tgctaatgta ttaacaattt tttcgaaaga aattctccct
      241 ttttcacttt gtaactccgt catatagtct tgtaaaattg agagtttgct atttaatgcc
      301 ggagagatct ttttaggaac tgataccttg tttcttttat caggaattga aactggtcgg
      361 cctctttttt tcaatgtaat atttcttgtg ttactcaatg cactattgct aaagttatat
      421 tcaccgctta ttttcacatc ttggcgtttg ttattgggta ataatggctc aaattcacca
      481 ttctccatca ttttaggaat atcaaaatct ttaggcatta cttatgcaac tccttattat
      541 ttatttaaaa actcttgtct agcatctagt tctgccaaaa tatttataaa tacttggtgt
      601 gctttataat cccattgatc aaaatttcca tttttgtatt ttcttaaatg tataccaatt
      661 ttagaatacc ttctcaatct tttttgataa tgaatgagat ttttggatac cacggttccg
      721 tatttttcaa ttgcttcttc taggatttct tcatcaaaat catcatttgg ttctaccata
      781 caaggtacaa tatctataat ttgcaaatca agatcgtatc tatcgaccat gaatttttga
      841 taatttacat atttgttgac tccctctaag gattcttcag ctgtttgaaa tgaaattatc
      901 gaatagtctg aagctgccat agcattatcg gaaaattcgc taatggttgg tggtacatca
      961 ataaatattt cttgataatt gttctttatt ggaagaagta attttttcaa gacagtaact
     1021 tggtctaatt cattttcatg tttattagca aaagcggaga atgatcgaaa actagtgtca
     1081 catgccagaa ggtcaagatt ttcatttacc ttaataatac tacttgctaa ttctccattt
     1141 gcgacaccat ttgttatagt ggttttgata tcggttatac cgaaagttct tgctatgact
     1201 tgtgttaagt tcgcttgagg gtctaaatca ataataagcg tttttctatt tcttatcatt
     1261 gcattgtcat aagcaagcat gctgactatc ttagttttac ctactcctcc tttaaaattg
     1321 ccaactgtaa atgtagtccc ttgaaaagta tccatgtaaa tcctcccaat ctttaattga
     1381 taattaaagt ataacttata tatcggaaat ggtcaacatt aaaagtataa cttaaataat
     1441 aatatctaaa aacgtttgga tatagcggtt tttaataata aaagtataag ttataccata
     1501 tatatttatg gtataactta tacttttatt atttaaggta taacttatac cttaaatatt
     1561 gcttttcgaa aatagctatt ctagtctatc tgtttcttta cttttcgctg ctgatttgaa
     1621 ttgaattgat catattcatt ttctagtatt aataactttt cgtatacatc ggtcatattc
     1681 atactagaag caagacttag atcatatac
//
LOCUS       DAPBCF010000146         1693 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.155, whole genome shotgun sequence.
ACCESSION   DAPBCF010000146 DAPBCF010000000
VERSION     DAPBCF010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1693
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.155"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            197..886
                     /locus_tag="RD508_002951"
     CDS             197..886
                     /locus_tag="RD508_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDT7737452.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            900..>1693
                     /locus_tag="RD508_002952"
     CDS             900..>1693
                     /locus_tag="RD508_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7737453.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAG"
BASE COUNT          548 a          238 c          333 g          574 t
ORIGIN      
        1 tggataattt tctttaatta aatagatata actcatacaa actcctctac aatttcaact
       61 tttctccatt atactccaaa ataataaaaa aaactcctaa atactccatt tttatcttta
      121 cttttatgaa agcggatgct atattgtttt tggagttatt atccaaaaat aataaaaaat
      181 tggagcgttt aggataatgg ataaaaagag gtttttagat cttatttcaa aaggtttgat
      241 tgtttcatgt caagcattac ctggtgaacc attttacaaa gaggaagaaa gtttaatgcc
      301 ttattttgct ttggctgctc aaagggctgg agcagttggt atacgtgcaa attctgttcg
      361 agatattatt gaaattagaa agtgtgtatc attaccaatg attggaatta ttaaaagaga
      421 ttatccacca gaatctccat tcattactgc cactatgaga gaagtagatg aattagtaga
      481 aaccggtgtt gaggtaatcg ctcttgattg cactcttaga aatcgacatg atggactatc
      541 tataaattct tttattacta aaataaaaga aaaatatcct catcagttat ttatggcaga
      601 tatttctaca tttgaagaag gcaaaaatgc atataaagca ggaatagatt ttgtaggaac
      661 tactttaagt ggatatactg aggaaagtaa aaaacaagat gggccagata tagatttgat
      721 taaaaaattg gtagaagaag ggatttgtgt aattgctgag ggaaggattc atactccaga
      781 acaagcaaaa gagataaaaa aaataggagt tgcaggtatt gttgtgggtg gtgctattac
      841 tcgaccacag gaaattgcat caagatttgt taaagcatta agttaggggg agaaataaaa
      901 tgtttaaaaa attttcacaa ttaggacgcg ctttcatgtt accaattgct atattaccag
      961 tagccggatt actattggga ctgggaggag cgttaacaaa tgagagtgct ataaatgctt
     1021 atccattttt agatcaaccg tggttgcata caattttaag tattatgagt tatgctggaa
     1081 atgcagtttt tgcaaaccta gcactaattt ttgcaattgg tattgctgta ggacttgcaa
     1141 atggagataa aggaacagct ggtttagctg gtggagtagc ttatttagta tatactgcaa
     1201 ctattagtgg gtttcttgaa cttttttcag caaaagatgc aacactagat acaggtgtag
     1261 tgggatcaat tgttgttggt ggtactgttg catttttaca caatcgttat agaaaaattg
     1321 aattaccaca attcttaggt ttttttggag gatcaagatt tattccgatt gtttctagtt
     1381 tagctgcaat cattattggt tctttctttt atttaatttg gccaccaatt caaaatggtt
     1441 tagtagttgc tggtgaacaa attgcccaaa tgggtagttt aggaactttt ttatatggtt
     1501 ttttattgcg tttaacaggt gctgttggac tacaccacac catttaccct ttgttctggt
     1561 atacatcttt aggtggtacc gaaactgtag ctggatcaac aattgctgga gcccaaaata
     1621 ttttctttgc ccaactagct gatccaaacc acactggtct gtttacttat ggtactagat
     1681 tttttgcagg aag
//
LOCUS       DAPBCF010000147         1655 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.156, whole genome shotgun sequence.
ACCESSION   DAPBCF010000147 DAPBCF010000000
VERSION     DAPBCF010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.156"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(9..>1655)
                     /locus_tag="RD508_002953"
     rRNA            complement(9..>1655)
                     /locus_tag="RD508_002953"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          351 a          509 c          352 g          443 t
ORIGIN      
        1 ttaacctatt ggttaagtcc tcgatcgatt agtatcagtc cgctccatac atcactgtac
       61 ttccactcct gacctatcta cctgatcatc tctcagggat cttactttct taaagaaatg
      121 ggaaatctca tcttgaggtg ggcttcacac ttagatgctt tcagcgttta tcccttccct
      181 acatagctac ccagcaatgc ccttggcaga acaactggta caccagcggt aagtccatcc
      241 cggtcctctc gtactaagga cagctcctct caaatttcca acgcccgcga cggataggga
      301 ccgaactgtc tcacgacgtt ctgaacccag ctcgcgtgcc gctttaatgg gcgaacagcc
      361 caacccttgg gaccgactac agccccagga tgcgacgagc cgacatcgag gtgccaaacc
      421 tccccgtcga tgtggactct tgggggagat aagcctgtta tccccagggt agcttttatc
      481 cgttgagcga tggcccttcc atgcggaacc accggatcac taagcccgac tttcgtccct
      541 gctcgacttg ttggtctcgc agtcaagctc ccttctgcct ttacactctt cgaatgattt
      601 ccaaccattc tgagggaacc tttgggcgcc tccgttacct tttaggaggc gaccgcccca
      661 gtcaaactgc ccatctgaca ctgtctccca ccacgattag tggtgcgggt tagagtggcc
      721 ataacgcagg ggtagtatcc caccagcgcc tccatcgaaa ctagcgttcc gatttctacg
      781 gctcctacct atcctgtaca tgcggtacag acactcaata tcaaactaca gtaaagctcc
      841 atggggtctt tccgtcctgt cgcgggtaac ctgcatcttc acaggtacta aaatttcacc
      901 gagtctctcg ttgagacagt gcccaaatcg ttacgccttt cgtgcgggtc ggaacttacc
      961 cgacaaggaa tttcgctacc ttaggaccgt tatagttacg gccgccgttt actggggctt
     1021 caattcgtac cttcgcttgc gctaagcact cctcttaacc ttccagcacc gggcaggcgt
     1081 cagcccctat acttcatctt acgattttgc agagacctgt gtttttgata aacagtcgct
     1141 tgggcctatt cactgcggct gatcgtatga tcagcacccc ttctcccgaa gttacggggt
     1201 cattttgccg agttccttaa cgagagttct ctcgctcacc ttaggattct ctcctcgact
     1261 acctgtgtcg gtttgcggta cgggccgctg ttttctcact agaagctttt ctcggcagtg
     1321 tgacatcagg aacttcggta ctattatttc cctccccatc acagcttgtc cttaagaaaa
     1381 gaagcatttg actcctcttc agacttactg cttggacaga catttccgat cgtctgcatt
     1441 ccttagcctc ctgcgtccct ccattgctca aacaaaaaca acgggtacag gaatatcaac
     1501 ctgttatcca tcgcctacgc ctgtcggcct cggcttaggt cccgactaac cctgggcgga
     1561 cgagccttcc ccaggaaacc ttagtcattc ggtggacagg attctcacct gtctttcgct
     1621 actcataccg gcattctcac ttctaagcgc tccag
//
LOCUS       DAPBCF010000148         1654 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.157, whole genome shotgun sequence.
ACCESSION   DAPBCF010000148 DAPBCF010000000
VERSION     DAPBCF010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.157"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..146)
                     /locus_tag="RD508_002954"
     CDS             complement(<1..146)
                     /locus_tag="RD508_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7737454.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIV"
     gene            complement(167..661)
                     /locus_tag="RD508_002955"
     CDS             complement(167..661)
                     /locus_tag="RD508_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7737455.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(673..1161)
                     /locus_tag="RD508_002956"
     CDS             complement(673..1161)
                     /locus_tag="RD508_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7737456.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(1238..>1654)
                     /locus_tag="RD508_002957"
     CDS             complement(1238..>1654)
                     /locus_tag="RD508_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7737457.1"
                     /translation="EHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNPTIVMSE
                     VETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKPDEDEFY
                     YVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
BASE COUNT          497 a          379 c          235 g          543 t
ORIGIN      
        1 acaatcaacc ccgtctgcaa atcccccatc aacgctcctg ctaacggagc aacaacaatc
       61 ggacgactca gcatggacat cccgaacatt tcatgtccag caactccaat aaaaacggcc
      121 aaagcgacta caaatgcatc atacataatt tttctccttc ctttttctaa aaatcactca
      181 aaatagagat agctgaacgt ttttccatcg ccggtgtagg ctgaaaaacg gtatctggat
      241 aaagttcaac taattctttt aagtcttgaa tttctgacgt cgttaacatc acttcctttg
      301 ataaggtttt cttatcttcc gatggcggtg tcattttccc agcattcccc acgttcatta
      361 attcgatttc cgttgggaaa gctttcgcaa cttttaccgc atctttgaca ttagggacta
      421 aaaccatcaa gcgcatgtcc ttcgcccgcg gatcttttaa caaatgaatc gcgtcatcaa
      481 ctgttttaat aatgactttg acattcgatg gtgcagccat cttcaatgtc atcttttgaa
      541 tatcgttggt agccgcctca tcgcttgcta ctactaaccc ggttaaattt agactctttg
      601 tccaagtcat cgctacttgt ccatgaatta atcgttcatc aattcgcact gctttaatca
      661 tttttcttcc tcctaaaaaa aatcttcctc ttcatttact acatgtacct catcaagaat
      721 ggtcatcttt aattcctgtt ggcatttatt taccagttcc tgaatatcct cctttgttaa
      781 ttccttggtt gccaatacta tttcgagcag aattggcaga ttaaagccag acaaaatagt
      841 tacagcaatc tctttctcca aaaaggtttt ggtaatcttc tgattgacac ttccgccaaa
      901 taaatcggta aaaacaaaaa tctgatcctg ctcgttcacc tggtttacaa atacattcaa
      961 ctcctgttca aaatcacact catccacata agcattaatc accgtaatct cttgaacctt
     1021 ccccgtcagt aattgaatac tgctaagaaa gcctgaagct aagtgaccgt gagtcgctat
     1081 tagaattttc ttcatatggt taattccttt ctttctgttc acttttatat aagcaattcc
     1141 tgtgccaact tttaaaaaca ttggtttaat cacgttaatt cacattaaaa aaagtgtcta
     1201 acctaaaaaa aacagattag acactttttt agacacttta tttttgaata tacggtccta
     1261 ataattcata gagcagcgaa agctcataag cattgacttt aaaattatat ttcatctcca
     1321 ttgattgaaa aatacttcta gaaacataat aaaattcatc ttcatctggt ttcaaatcat
     1381 aattcggttc ttcagatttt tctgtccgag ccaagaataa acgttccatc atcaatgccg
     1441 tatgcatata gagatttagt tttacacggc catttaaagt gaaatgatag taattttcat
     1501 atttagaaat gactgtttcc acttcactca tcacgatcgt tgggttcaga aagttcaaac
     1561 ggtccgcaat tccttccaac gaaaagaatt ttactagctc ctgaatcaag cggttaaatt
     1621 ctgccggctt catttcagga ctcaaaatat gctc
//
LOCUS       DAPBCF010000149         1644 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.158, whole genome shotgun sequence.
ACCESSION   DAPBCF010000149 DAPBCF010000000
VERSION     DAPBCF010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.158"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..498)
                     /locus_tag="RD508_002958"
     CDS             complement(<1..498)
                     /locus_tag="RD508_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7737458.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSP
                     SYCEHCRSVRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQSRMNFLPTVL
                     CMDEFK"
     gene            699..1644
                     /locus_tag="RD508_002959"
                     /pseudo
     CDS             699..1644
                     /locus_tag="RD508_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          501 a          325 c          319 g          499 t
ORIGIN      
        1 tttgaactca tccatacaca acaccgtcgg aaggaagttc atacgtgact ggtaatgctt
       61 cgttgcttca cgcaagatcc gtgtcaccgt cccatccgag acgaagtact tcttagcgat
      121 tagtttacgt gattgatttt cgtacagttc catgagaatt gcctgcttca gttcctttgt
      181 tagttgatga tgttcatcaa ctaagtccgt tttcgcagaa aaggtccttc cacaatcatg
      241 gcagagaaaa cgggtacgtt ttaattctaa aatagttaac ttttctttga ctttcaatat
      301 ctgagtgcgt gtcgtatagg aaccgttgcg gataatacga accgatcgac agtgttcaca
      361 ataggaagga gagtcatcca attttccttt aataaactgc gcttgaacgc ctttatattc
      421 tttttcaatc agccattctt catcaaaaaa taaatgttta tctgttaatc cgagtaattt
      481 tctagtatga ttatccattg agagactcct ttggtaggat gacgttttgg tcgactaaat
      541 tttaccaaaa gtgagtctct ttttgagttg aaacgaagaa aaagtgttag tagaaaatcg
      601 ccttcgattt tccaccaaca caaaatatta tagaagcaaa atcaattcta ccttagatgt
      661 tcttatatca ctctatcagt cctatttgac aaagagccaa gaaaaagacg ttggtcgtcg
      721 atgctgttct ctcgcctact cctcgtgctt gtagaagttg tggttctact gtggtagatg
      781 gaaacgggaa agcaattata gtgaaaaatg ggaagaagga aacgattgtc cgttttgaac
      841 aatacaatca tatgcctttg gttacgcgcc taaaaaagca acgctatacc tgtaaaaact
      901 gtcgtaccca ttggacggct caaagttatt ttgtccgact cagccattca atcgcagatc
      961 atgttcgata taaaattgct tctttactga ctgaaaaagt atctttgtct tttattgcga
     1021 aaagttgtca ggtatctttg actaccgtta ctcgtacatt gaaagagttt aaaagctatt
     1081 taccaaagcc ttctaagaag attctcccca gagtattgat ggttgatgaa tttcgttcgc
     1141 acgcttccat agaagataaa atgagcttta tttgcgcaga tggtgaaaca ggaaacttaa
     1201 ttgctgtctt gcctacgcgt aaattacctc gattaacaag ctatttctta ggctgcacca
     1261 atccagaaga agtagaattc ttagtcacag acatgaacgc cgcttacttc cagcttacca
     1321 aacgtgttct gccaaatgcg aaagtagtga ttgatcggtt tcatattgtc aaacacatga
     1381 atcaggcact caatgagttg cgtatccgtg aaatgaatga gcttcgtaaa gcaggacaga
     1441 aaagtcaggc agaaaaactg aaaaagaact ggcgctttct gctaaaaaat cgtgcaagca
     1501 tcaaccatta tgagtacaaa acatggaaaa gtttccgagc accaaaatac ccatttctca
     1561 ctgaagcaat gatgattgat cgattgcttg agttttctgc gcctctaaag gaggcgtatc
     1621 ccttttttca tgaattagtc gaag
//
LOCUS       DAPBCF010000150         1617 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.159, whole genome shotgun sequence.
ACCESSION   DAPBCF010000150 DAPBCF010000000
VERSION     DAPBCF010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.159"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..247
                     /locus_tag="RD508_002960"
     CDS             <1..247
                     /locus_tag="RD508_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HDT7737459.1"
                     /translation="PHYLPGDVKPVDRIMIKGLNQDHSEWAYISRNLKYRLRKLLKEE
                     SQNDELTNHLRETFKESANDLKIELDTWLLGLDVTEK"
     gene            447..650
                     /locus_tag="RD508_002961"
     CDS             447..650
                     /locus_tag="RD508_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737460.1"
                     /translation="MSQLGKCYSLSKSNRKVYTLFISDSAKEGFNLGFSISFKKGTKN
                     TSISHNNRELTDSQKINSLSGRK"
     gene            1210..>1617
                     /locus_tag="RD508_002962"
     CDS             1210..>1617
                     /locus_tag="RD508_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HDT7737461.1"
                     /translation="MSKKGIIVNEWEKLNRISNRRLSVDDKVHPLKLSWSIDRITIVG
                     KLNDTIAYWTQNGVVFVDFEQLMRLNENQGYLKSVGTNGWQLFDQYGEDIAYIEMLKF
                     HPDKGRIDFNPNKIGEFLKGSMKQFIHDLFLDAH"
BASE COUNT          531 a          233 c          374 g          479 t
ORIGIN      
        1 tcctcattac ttgcctggag atgtaaaacc tgttgataga attatgataa aagggctgaa
       61 tcaagatcat tcagagtggg cgtatattag cagaaatttg aaatatagat tgcgcaaatt
      121 gttgaaagaa gaaagccaaa acgatgagtt gacgaatcat ttacgagaga cgtttaagga
      181 atctgcaaac gacttgaaaa tagaattaga cacgtggctt ttgggtttgg acgtgacaga
      241 gaagtgatac cgaataagaa aagtcagatg agtgagagta aatttacgtc aatgtttaat
      301 gacgtgagtt tacgataagc gattattttg cgtgaagcaa aataaagcgt aaaaggagtt
      361 gagagcgtga cacgctttcg gctccttttt tcgttgtcac ttgtgacagc gaataccctc
      421 ggagagcatt tggaattgtg acagccatgt cacaattagg aaaatgttac tctttgtcaa
      481 agagtaacag aaaggtttac actcttttta ttagcgacag cgcgaaggag gggtttaact
      541 tggggtttag tatttcgttc aaaaagggaa caaaaaatac aagcatttct cataataatc
      601 gtgagttaac tgatagccaa aaaatcaata gtttgtctgg tagaaaataa ttagcagatt
      661 tacaagtggg aaataaaaag ctgaaagaag aaaattgcat ttcaaactat attttctaca
      721 atagctctaa aatggcatat tttgcgttct gagcggtttt agcgtttatt tcgtttagtt
      781 atcggcacaa tcggtgaaac acgttagagg agcgaaaatg gagcctgtaa ggcgactggt
      841 agcggaacgg tcgtgttaga ttgtgtagcc gatagctgaa cgaaataaat gctggcagcg
      901 ccattctatt tcggcaggag gaggctcaag gggttcgggg aatgaaattc cctgaggtct
      961 ttttattttt tctagaggag tgctataatc aaagaaaatg agaaaaaaga gtaaaaaaat
     1021 agtcgagcag tgttgacgca ctctcgacct ttacggaaac tacttcacct agttccgtaa
     1081 ctcaagttca ttatacgaat atttttaggt ttcttcaagc tagagatttt tggatgtgga
     1141 tttttagagt tacgtgaact ctggaaattc tttccaagaa tctctttttt cgttgaggag
     1201 gagctatttt tgagtaaaaa aggcataatc gtaaatgagt gggaaaaact taaccgtatt
     1261 tctaacaggc ggttaagtgt tgacgataag gtacaccccc taaaattaag ttggtcaatc
     1321 gatcgaatta caatcgtcgg aaaactgaat gataccatag cttattggac gcaaaatgga
     1381 gttgtgtttg tcgattttga gcaattaatg cgtttgaatg aaaatcaagg gtatttgaag
     1441 tcggttggta caaatggttg gcaattattt gaccaatatg gagaagatat cgcctatatc
     1501 gaaatgttaa aatttcaccc tgacaaaggt cgtattgatt ttaatccaaa taaaattggc
     1561 gagtttttaa aggggtcgat gaaacaattc attcatgatt tgtttctgga tgcgcat
//
LOCUS       DAPBCF010000151         1563 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.160, whole genome shotgun sequence.
ACCESSION   DAPBCF010000151 DAPBCF010000000
VERSION     DAPBCF010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1563
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.160"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            46..105
                     /gene="ermCL"
                     /locus_tag="RD508_002963"
     CDS             46..105
                     /gene="ermCL"
                     /locus_tag="RD508_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methylase leader peptide ErmCL"
                     /protein_id="HDT7737462.1"
                     /translation="MGIFSIFVINTVHYQPNKK"
     gene            153..887
                     /locus_tag="RD508_002964"
     CDS             153..887
                     /locus_tag="RD508_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(T)"
                     /protein_id="HDT7737463.1"
                     /translation="MNKKNIKDSQNFITSKHHINEILRNVHLNTNDNIIEIGSGKGHF
                     TFELAKRCNYVTAIEIDPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIYGNI
                     PYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPR
                     EYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKY
                     ARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          585 a          247 c          211 g          520 t
ORIGIN      
        1 cttgtgctat aattattcta atttcataaa aaggagaatt aatatatggg catttttagt
       61 atttttgtaa tcaacacagt tcattatcaa ccaaacaaaa aataagtggt tataatggat
      121 tgttaatata aacctcatag gagtgggtta taatgaacaa aaaaaatata aaagatagtc
      181 aaaactttat tacttcaaag catcatataa atgaaatttt gagaaatgta catttaaata
      241 caaatgataa tattattgag attggttcag ggaaaggtca tttcacgttt gaattagcta
      301 aaaggtgtaa ttatgtaacc gccattgaaa tagatcctaa attatgtagg ataactaaaa
      361 acaaacttat tgaatatgag aacttccagg ttatcaataa agatatttta caatttaagt
      421 ttcctaaaaa taagtcatat aagatatatg gaaatatacc ctacaatata agtacagata
      481 taattcgaaa aattgttttt gaaagcacag ctacagaaag ttatttaata gtggaatatg
      541 gatttgctaa aaggttgcta aatacaaatc gttcactagc actattttta atgacagaag
      601 ttgatatatc catattaagt aaaatcccta gagaatactt tcatccaaaa cctagagtta
      661 atagctcgtt aattgtatta aaaagacacc cttcaaaaat atcactcaaa gatagaaaac
      721 aatatgaaaa ttttgttatg aaatgggtta acaaagaata cataaaacta ttttccaaaa
      781 accaatttta tcaagcctta aaatatgcaa gaattgacga tttaaacaat attagctttg
      841 aacaattctt gtctcttttc aatagctata aattatttaa tagataagtt aaggggtgca
      901 taaactgcat cccttaactt atcttatttt gcttaaacaa tcttggcccg taaactgcat
      961 aactcatatg taaatcgctc ctttttaggt ggcacaaatg tgaggcattt tcactatttc
     1021 cggcaattac ttccatgtaa agtataaccc actatacttt gcaagcaaag tgtgggctcg
     1081 ccgaggggtc ttgcagacgg ctctttcggc tcttttgagc cgagtatcag cgcaccctta
     1141 tggtgcaatt agctgatacc tgtttgacga tttgctgccc taccttttcg gtaggtatgc
     1201 aaacctcaaa ccaaaataaa aacccccttc gacttcgtca gggggttttt atttatataa
     1261 atctccgtaa ataatcgcga tttaataaca tcttcaattt tatttttttg cgtattttag
     1321 aaatgttttc actaaaaaat atattataca aaaaatacag taatcgatta taattctttg
     1381 ccagttaaat atcatatcgt tattaaaata tcggaaaaaa atatcaacaa caataaatgc
     1441 aaaagaagac cataaaaatt gtttattact catacatact ctccatttct atcattttta
     1501 aatttaccag tcatctctca aaaatctcct agctattttt cttttttaac cacataccgt
     1561 caa
//
LOCUS       DAPBCF010000152         1540 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.161, whole genome shotgun sequence.
ACCESSION   DAPBCF010000152 DAPBCF010000000
VERSION     DAPBCF010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1540
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.161"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..171
                     /locus_tag="RD508_002965"
     CDS             <1..171
                     /locus_tag="RD508_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HDT7737464.1"
                     /translation="IFSMIDEQEPTESKRHRAQGIIKIAKRMFSIKGVLSYTVLIQKI
                     PNHLVYKNNVED"
     gene            complement(394..492)
                     /locus_tag="RD508_002966"
                     /pseudo
     CDS             complement(394..492)
                     /locus_tag="RD508_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(757..1212)
                     /gene="tnpA"
                     /locus_tag="RD508_002967"
     CDS             complement(757..1212)
                     /gene="tnpA"
                     /locus_tag="RD508_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDT7737465.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
BASE COUNT          458 a          283 c          247 g          552 t
ORIGIN      
        1 attttttcca tgatcgatga gcaggaacct actgaatcta aacgacatcg ggcacaagga
       61 attattaaga ttgctaagcg aatgttttct ataaagggtg ttctaagcta tacagtgtta
      121 attcaaaaga ttcccaatca tcttgtttat aagaacaacg ttgaagatta aaaaagtgtt
      181 tcaatgctaa aattgcaaaa tacttcaatg ttatgagaca aactgtctat aagaatcaat
      241 ttccacccat ttcatcactt gttaaaagtt tatgatcctt ttgattttta tattaattta
      301 tctgtattta atacagattt tatttattag ttcatctgcc tattgtattt tattttgttg
      361 ccttaccatc tgaagtaaat atactcttaa ttgtcaaatt aagttagaca gatcatcaat
      421 acttacgtaa ctcaaaaata cttccaaagg tgttcgataa tccagtgatt ttctaggaag
      481 attatttctg cgccagcatt ttctaatgtt tgaatttgtg ttttgtaatc ttggttgctt
      541 gtgctaattc ttgaatagcc gtaaattgcc aaaatttcat caccctttct ggacataagt
      601 ttctgacacc agttaaaatc aagtctatca gtaacccata cacccgtgag gacgggtgta
      661 tttttaatcc ccctagaagg ggtcgacact cgctgcccct taaaagggga tttttaaaag
      721 accgccaact gctcatcttc actcacttac ttctctttat tttttaaatg gttctacgta
      781 ctctctttta cttataatat atcgaatgcg atcatcagct tcttgttcac ggatgtattt
      841 ttcatttgtc ttttgattca atccgactgt actcacatag tatctcttcg accaaaagga
      901 tttgtttccg tatttatatt tgagatttgc gtgctgctcg tggattagta ccgcactacg
      961 acctttcaga taccccataa aactggatat acatattttt ggtggtactc gaacaagcat
     1021 gtgaatatga tctagcattg catgtgcttc tatgatttcc acatctttca tttcgcacaa
     1081 cttcctaagt atttttccaa gatcttttcg taattgccca tagattactt ttcgttgata
     1141 ttttggtgta aaaataatat gatacttaca attccaacga gtatatgcta aacttttatc
     1201 gtcatttgac atgaaaaaac tcctttcgat ctgatgagcg gttggtagcc actcactagt
     1261 atatcgaaag gagtttttat cgctaaagat acttcttcca cgcgtagaaa cgcgcggttt
     1321 tcttgtttcg cacgctttac gcacaaaact gactgaagtc attaagaaaa taaaagggtc
     1381 taaaactttt aagttttgta ccgaccccca aaagttagac caaaaaatct aacttttgga
     1441 ggtcggtatt ttttatggct aagtatactt ttgaacttaa attaaagatc gttcatgatt
     1501 acttggatgg taaaggcgga agtgattatc tggcaaagaa
//
LOCUS       DAPBCF010000153         1513 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.162, whole genome shotgun sequence.
ACCESSION   DAPBCF010000153 DAPBCF010000000
VERSION     DAPBCF010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.162"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..613)
                     /locus_tag="RD508_002968"
     CDS             complement(<1..613)
                     /locus_tag="RD508_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7737466.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFL"
     gene            901..>1513
                     /locus_tag="RD508_002969"
     CDS             901..>1513
                     /locus_tag="RD508_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7737467.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCI"
BASE COUNT          533 a          217 c          285 g          478 t
ORIGIN      
        1 gcaggaagta ttgagttagt ttgtaaagtc tgcgatcttc aaggatcgta aatagctgat
       61 gggttgtccc atcaacacaa ataaaactca tggaaccaga aacagacttc attgatttga
      121 actcatccat acacaacacc gtcggaagga agttcatacg tggctggtaa tgcttcgttg
      181 cttcacgcaa gatccgtgtc accgtcccat ccgagacgaa gtacttctta gcgattagtt
      241 tacgtgattg attttcgtac agttctatga gaatcgcctg cttcagttcc tttgttagtt
      301 gatgatgttc atcaactaag tccgttttcg cagaaaaggt ctgcccacaa tcatagcata
      361 gaaaacgggt acgttttaat tctaaaatag tcaacttttc tttgactttc aatatctgag
      421 tacgtgtcgt ataggaaccg ttgcggataa tacgaatcga tccacagtgt tcacaatggg
      481 aaggtgagtc atccaatctc cctttaataa actgcgcttg aacgccttta tattcttttt
      541 caatcagcca ttcttcatca aaaaataaat gtttatctgt taatccgagt aattttctag
      601 tatgattatc catagagcga ctcctttggt agggtgatgt tttggtcgac taaattttac
      661 caaaagtgag tctctttttg agttgaaacg aagaaaaagt gttagtagaa aatcgccttc
      721 gattttccaa caacacaaaa tattatagaa ccctttattc taaaggattt caaggtgtct
      781 gtttgcattt attagaaaaa agaaaaagta ttggcaacag aaggtgtcac caacactaga
      841 tattatagag ccataatatg ctgtataata tctagtgtat aggcttaagt ggaggtatat
      901 atgaaaatat taactgttga agatgataat atgataagag agggaataag tgaatatctt
      961 tcagaatttg gatatactgt tattcaagct aaagatggaa gagaagcctt gtcaaaattt
     1021 aatagcgata taaatttggt tatcttagac attcagatac cttttataaa tggtttagaa
     1081 gtgttgaaag aaattagaaa gaaaagcaat ttaccaattc taatcttgac tgcatttagt
     1141 gatgaagaat ataaaattga tgcatttact aatttagtag acggatatgt agaaaagcca
     1201 ttttcattgc cggtcttaaa agctagaata gattctttaa ttaagaagaa ttatggacat
     1261 ttagagaagt ttgaatataa ggatctatcg gttaatttta atagctatac agctaaaata
     1321 aatggtgaag aaatagatgt aaatgcaaaa gaactagaag tattaaaatg tttattggat
     1381 aataatggac aagtgttaac aagaatgcaa attattgatt atgtatggaa agatagcgaa
     1441 gaaactcctt atgatcgagt aatagatgta tatataaaag aacttagaaa aaaattacaa
     1501 ttagactgta taa
//
LOCUS       DAPBCF010000154         1458 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.163, whole genome shotgun sequence.
ACCESSION   DAPBCF010000154 DAPBCF010000000
VERSION     DAPBCF010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.163"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(9..1148)
                     /locus_tag="RD508_002970"
     CDS             complement(9..1148)
                     /locus_tag="RD508_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HDT7737468.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT          381 a          314 c          264 g          499 t
ORIGIN      
        1 aaaaaatctt acgctaagta ggataaaata attccttgat atttttcgat catatccaaa
       61 taattatcga tttcaacata ctcatctact tgatgaggca aagtaacgac accaggccca
      121 aagacgacaa agtcgaagga atggttagct ttcgtaaatt cggctgcatc cgttgttgct
      181 gccgctccaa ctaaaggtaa tggctggctg aattgttgct gaatgcaatg aatcaaagga
      241 gaatctggat cagctttgac aggtattttg ttgtaatcga tcatcaattc caaatgatag
      301 tctgtctctt gattcaattc attgacgatt gattgcagca atgcaatgat tttatcattt
      361 gggtattctg gaatcgatcg aatgttccct tggagctgcg catggcttgg gatgctgttg
      421 acttgattcc cgccactgat caatgtaaca ttatggattg tttttcctag gacaggattc
      481 tcgattgttt cagcgaggtg attcatttca gcatttgctt tcgtaatgaa ttcatttagg
      541 tgattgattg cattataacc ttggtctggc atagagctat gcgcttcttt tccgtgcgag
      601 gtgactgtat agttgattga tcccatgtgc gtatacatca aactgtaatt ggttggctct
      661 ccgatgatca aggcatctaa gtcatctaca tagcctgctt tcgtgagctg ttccccacct
      721 agttcaccca cttcttctcc gacagtggct aataatttga ctgttccgtt aaatggtttt
      781 cctgactctt tcagttcgat catggcaatc accattgctg ccaagccact cttcatatct
      841 gtagcaccac gtccgtacaa acggttccca tggatttctg ctgcaaaggg tgcataggtc
      901 caagacgatt catcaccagc cgccacgaca tccatatgcc cagataggcc taacactttt
      961 cctgattggc ccttttggta acgagcaatc aaattatctc taccatctct gtaagaaaca
     1021 atctctcctg ttatgtcatg ttttgccaaa agcttattca aataggctgc tacttcacct
     1081 tcgtttccat tcactgattt aattcggatg atctcttgta aaatcgcgat tttttcttct
     1141 tttttcatct aatcctctcc cttgccattt ctttttattg tatttgagtg tgctcgaatt
     1201 ttcaaatagg agcaaccaaa gtaaaaatga agaaagagag ccactttatg aaaaatatgc
     1261 tgctacttcc ctcctatttt atttatacga gaggacttgc tcatagattc ctattctact
     1321 gttctatcct taaaagctct tatatgatgc tagttattgt tagctttcct ttttcaagga
     1381 tgatcttttc ttgtaccatt ctttgtaaac atcatataca gaagctagtt gcaaaaaaac
     1441 tctctacctg ctgatatt
//
LOCUS       DAPBCF010000155         1354 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.164, whole genome shotgun sequence.
ACCESSION   DAPBCF010000155 DAPBCF010000000
VERSION     DAPBCF010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.164"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            82..>1354
                     /locus_tag="RD508_002971"
     CDS             82..>1354
                     /locus_tag="RD508_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HDT7737469.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLI"
BASE COUNT          460 a          261 c          257 g          376 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atca
//
LOCUS       DAPBCF010000156         1299 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.165, whole genome shotgun sequence.
ACCESSION   DAPBCF010000156 DAPBCF010000000
VERSION     DAPBCF010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.165"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(602..675)
                     /locus_tag="RD508_002972"
     tRNA            complement(602..675)
                     /locus_tag="RD508_002972"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(639..641),aa:Ile,seq:cat)
     gene            complement(865..>1299)
                     /locus_tag="RD508_002973"
     CDS             complement(865..>1299)
                     /locus_tag="RD508_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7737470.1"
                     /translation="TDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGEIENA
                     NLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYHVSFN
                     MRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          408 a          235 c          231 g          425 t
ORIGIN      
        1 gactgacgtg ccggacgcac gtagcgatca tcggcgttat gactatataa agtatacttt
       61 cgttgatcca gaaaggtata aagattaaag taggctacct aaaaaggtag cccggaacga
      121 attttatcac catacttgtg aaaggagata ttttttaagt tagtattaag attgtgtaat
      181 atgatgatat ctatatttta tagtatcagt gctataaaat caaaaataag tcactaatta
      241 actaccactc caattgtaag ccttttttct cacttttttt caaaaatatg gtatgctttt
      301 taatggcttc aaatataaaa gagtttaaag cgtaacacac ttatggggaa gtggtttggg
      361 gtgcgcttta aactcttctt tattattatc tcacaattta acccaaatgt ctttctattt
      421 aaaaatcaaa gtaaaacttt tcaaatatac agaagtataa ctatgtgaaa catcctttca
      481 ttaatccata aaaggataca taaaaaagcc actcatttga gtggcaatga agaaaagctt
      541 tagcttgtat aatactcttc aaaaaaattc taacacagaa cgattcaaat ggctacgtta
      601 atgtaccctg taggactcga acctacgacc ggacggttat gagccgtctg ctctgaccaa
      661 ctgagctaag ggtactggtt gttgccacat aaagccataa acaatcaacc agtagaatgt
      721 gtggcaacaa acctgttatc gcatagcttg gagtgtgact atttatgggt gatagtgaag
      781 atatgcgata acatcactat tttatcgaat aatttttata gttgtcaata tagttatgta
      841 ctgctcctca acgaggagct atttttatcg tttaggaata tttaaatacc aacgtttgtc
      901 atggaaatct tgcgcaccgc ctttagtgtt tccctctgga tcattcgttg cccgcatcat
      961 tacatagact ttcttactag gaaaattacg catattgaaa gatacatgat aaccaacatt
     1021 tccagaagta ttataagctt ggtttacatc tggtctataa attccatcag ctcttactcg
     1081 agctaattct ttcccagtat tgtagtccat aatgaaaata tactcgtatt tatagttagc
     1141 aatgtgccat ccagccacat gcaagtttgc gttttcgatt tccccaaact gatcaatgtg
     1201 ggcgtgattt gttccatctg tcagcgtagg attagctgca ccagctcgtg ttggatcaat
     1261 gacaggcttg ttttcagaag ttgttggatt ttcatcggt
//
LOCUS       DAPBCF010000157         1297 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.166, whole genome shotgun sequence.
ACCESSION   DAPBCF010000157 DAPBCF010000000
VERSION     DAPBCF010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.166"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..548)
                     /locus_tag="RD508_002974"
     CDS             complement(<1..548)
                     /locus_tag="RD508_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7737471.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAA"
     gene            complement(587..>1297)
                     /locus_tag="RD508_002975"
     CDS             complement(587..>1297)
                     /locus_tag="RD508_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HDT7737472.1"
                     /translation="EMPFQTSAKITIENLHPKDMSSFFYTINYALVDELEENSLYFHA
                     NWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLERYWWGEGEFKFYIDGDSEYPT
                     VTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYPYQSNRDATRDRFETGKLNAV
                     HAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGNDDVRLFERQDDVASVAYWYST
                     EASGNTKRHFTDRERLPR"
BASE COUNT          372 a          310 c          243 g          372 t
ORIGIN      
        1 gctgccatcc cctctaaaca atcttggtgg aagggacagt ttcctgaaaa attgtccttt
       61 ggatgtcgct tgatcaacat atgccccatt tccggatgac tgaacccttc cacgaaagtc
      121 ccattgaaca aggcaccacc tccgatacct gttcccacag tgaagtatgc aacacctgct
      181 aaccctttgc cagaaccagc aacatattca ccatagcaag ccgcattgac atctgttgtc
      241 cattcaatcg gaatattgaa atattgcttt agcgttccta caaaattgaa attttgccaa
      301 gcaagttttg gtgttgatgt gatatgaccg aaactcgttg atttgcattg aatatcaatt
      361 ggaccaaagc agccgacccc gatgcctgcc aattgttcct taaaaggttt aaaaaaatca
      421 atgacctgct tcattgtttc aactggagtt gttgtgggaa aactgactct ttccaaaatc
      481 gttaattcct cagtaccgac tgcacagaca aatttagtcc ctccagcttc aattgcccca
      541 tatatcatca taggttcctc ccttcgaata tgtgaaaaac acttcattaa cgcggcaagc
      601 gttctcgatc agtgaaatga cgtttagtat ttcctgaagc ttctgttgaa taccagtaag
      661 cgacactagc aacatcgtct tgccgctcaa ataagcgaac atcatcgttg ccgatttgtt
      721 gtaaagtgac cgataaatct tcggtaaaac agatggggtc ttgaagatgc caacgataaa
      781 gaccatgtcg tggcattgcg tcgtcaccaa aggcatgaac ggcattcaat tttcccgttt
      841 caaaacgatc tcttgtggca tctctatttg attggtaagg ataccctaaa aaggctgttg
      901 aatagttttt cgcatgtgga cgtccgaact catcgtactc atgaaaggcc cacgccccgc
      961 caaaataatc ttctgaacct gttgaggtta cggtcggata ctcactatcc ccatcaatgt
     1021 agaatttaaa ctcgccttcg ccccaccaat aacgttctag gcaggtaagc gcaaggtaag
     1081 tacccacgta atagccttga ccctttaatc gatcaattaa cttataatcc tcctgtaatt
     1141 tggtaatgcg ttcccgatgc caatttgcgt gaaaatatag gctattttct tccaattcgt
     1201 ccaccaaagc gtaatttatc gtataaaaaa atgaggacat atccttcgga tgtaaattct
     1261 cgatcgtaat tttagcggat gtttggaaag gcatttc
//
LOCUS       DAPBCF010000158         1262 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.167, whole genome shotgun sequence.
ACCESSION   DAPBCF010000158 DAPBCF010000000
VERSION     DAPBCF010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.167"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..1217)
                     /locus_tag="RD508_002976"
     CDS             complement(<1..1217)
                     /locus_tag="RD508_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7737473.1"
                     /translation="MQTFLTKTSFKKVVLLDYLLEKDNWCAMEELRNLLNVTEKSVLH
                     YIEELEDLFKQYNGNILLKNEDNKRFFIKKEKDFPIYNIYLHFYKASYNYHLIDFMYK
                     YPRSVLKDFAKEQFTSVSTVFRYAKLLIPYFRRYHITFHPFQLELNASEANIRSFFYY
                     FYWNSTRESSDKWPFHIEQKEIEKYIVAFEGIYDITLTIFQKRVFSFWLAINIERSSF
                     RKVRVDNEYKSVISDDPHFNLLKKWSKQINLSFNSDELCFLYRIIYSFGVIDGNAIYE
                     NSHAYAHQRQNTCSYRAVENLEKVLQSMFRFSLDIKDPELIFNFIAFHERSYLFYGNP
                     DLFFNRSYIEEMKEEEPRTYHIMEKLKKELQANADLDVSKKLENWAQLFLDYYYVLDY
                     YDLFLTNVKPIKI"
BASE COUNT          460 a          197 c          146 g          459 t
ORIGIN      
        1 aaaatcttaa tcggtttaac atttgttaaa aataaatcat aataatctaa cacataataa
       61 taatccaaaa ataattgtgc ccagttttct aatttctttg atacatccaa atccgcattt
      121 gcttgtaatt cttttttgag tttttccatt atgtgataag ttcgaggttc ttcttctttc
      181 atttcttcga tatacgaacg attaaaaaaa agatctggat taccataaaa tagataactt
      241 ctttcatgaa atgcaataaa attgaatatg agttctggat cctttatatc taaagaaaaa
      301 cggaacatgc tttgtaaaac tttctccaaa ttctcaactg ctcgataaga acaagtattt
      361 tgtcgctgat gtgcatatgc atgactattt tcatatattg catttccatc aattactcca
      421 aaagaataaa ttattcgata aaggaaacac agttcatcgc tgttaaaaga aagattgatt
      481 tgttttgacc acttcttcaa aagattaaaa tgcggatcat ctgagataac tgatttatat
      541 tcattatcta ctcgtacttt tctaaatgaa cttctttcta tattaatggc taaccaaaaa
      601 gaaaatacac gtttttgaaa aatagttaac gtaatatcat aaatcccctc aaaagcaact
      661 atatacttct ctatttcctt ttgttcgata tgaaatggcc acttatcact actttcacgt
      721 gtagaattcc aatagaaata ataaaaaaag ctacgaatgt ttgcctctga tgcattcaat
      781 tctaactgaa atggatgaaa tgttatatga taacgcctaa aatatggaat taagagcttc
      841 gcatatctga aaacagtaga tacactagta aattgctctt tagcaaaatc ttttagaaca
      901 cttctaggat atttatacat aaaatcaatc aaatgataat tataagaagc tttataaaaa
      961 tgaagataaa tattataaat aggaaaatct ttctcttttt ttatgaaaaa tcgtttatta
     1021 tcttcatttt tcagaaggat attaccatta tattgcttaa ataaatcctc tagttcttct
     1081 atatagtgta agactgactt ctccgtaaca ttaagtaaat ttctaagttc ttccattgca
     1141 caccaattgt ctttttctaa caaataatct aataaaacta cttttttgaa agatgtttta
     1201 gttaaaaaag tttgcatcat ttcacctcaa taagttactt ttgtttattt taatcaaaga
     1261 at
//
LOCUS       DAPBCF010000159         1246 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.168, whole genome shotgun sequence.
ACCESSION   DAPBCF010000159 DAPBCF010000000
VERSION     DAPBCF010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.168"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            200..742
                     /locus_tag="RD508_002977"
     CDS             200..742
                     /locus_tag="RD508_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737474.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="RD508_002978"
     CDS             898..>1246
                     /locus_tag="RD508_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDT7737475.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          515 a          141 c          238 g          352 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaaaacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DAPBCF010000160         1242 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.169, whole genome shotgun sequence.
ACCESSION   DAPBCF010000160 DAPBCF010000000
VERSION     DAPBCF010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.169"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..470)
                     /locus_tag="RD508_002979"
     CDS             complement(<1..470)
                     /locus_tag="RD508_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
                     /protein_id="HDT7737476.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELG"
     gene            920..>1242
                     /locus_tag="RD508_002980"
     CDS             920..>1242
                     /locus_tag="RD508_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7737477.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDK"
BASE COUNT          406 a          217 c          204 g          415 t
ORIGIN      
        1 cctagctctt ctttaatatt ctcctggatc atttgagcca gcttctttct ccgttgactt
       61 cgtgttcctt cagtcgtaaa aagattcagt gatcgggtca cttttaagat tgattcatcg
      121 atcgagtaaa tcagtagatc ttcatcagcc acatatcttc tgaaaatatt atttacctgc
      181 atatttcgct tgatatatag gttcatacgt ggtggaacaa cgtgtagtgt tttaggaaat
      241 ggttgtggta agtcacgtgg tctactcaca tttgtaatac cataccgctt ttttgcttca
      301 ggagaagaag ctaatatcaa tcctgaacca gtattatcag ctcgactcat aacaacaagt
      361 tctgttgtta atggatctaa atttctttct atacattcga cacttgcgta aaagcttttc
      421 atatcgatta aaaagtaatc atttactggc tcttttgaat aatccatcat aaataacact
      481 ccattctttc acattataca aacatatgtt cgatattgta aagaagaaat agctaaatac
      541 ataaaaaaag aagcataggt atgctatcac cctgcttctt cttttgattt gtatgatcaa
      601 tttattctat cactttacta attaatttga aaatctaata aaaactctca ctctaaaaga
      661 gtgagagact gcaaattaga gtacggactt ttttggagtt ccgttcttta atattaacaa
      721 atgaataaaa tccttacaac atttgagaat aagttatcag tagacactta caaaaaattc
      781 tcatactatt tcctccatca ttagtttttg tctatataag gtttacccta aatagacact
      841 ggtataacat tgaaaaatat ggcttcctcg tgtatgatta gggtgtattt taaatagttg
      901 cagaaagtag gtaaaagttt tgagagttgc atacatacgt gtctcatcga tcgatcaaaa
      961 tgaacaacgc cagattgaag aaatgaaaaa attcggtgca gagagaattt tcatcgagaa
     1021 acaatctggc gcaacgatta ctcatcgacc tgttttccaa gaagcattag attacgtccg
     1081 agatcaagat atttttattg tggaagctat tgatcgactt ggaagaaatt atgacgagat
     1141 catcgcttca gtcaattact tgaagaagaa aaatgtgaag ctgatcatta ctagtttacc
     1201 gatcatggct gaagcaattg gcaatcctct cctggataaa tt
//
LOCUS       DAPBCF010000161         1229 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.170, whole genome shotgun sequence.
ACCESSION   DAPBCF010000161 DAPBCF010000000
VERSION     DAPBCF010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.170"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..164)
                     /locus_tag="RD508_002981"
     CDS             complement(<1..164)
                     /locus_tag="RD508_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDT7737478.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTG"
BASE COUNT          503 a          177 c          188 g          361 t
ORIGIN      
        1 cccgtgttaa aaccaatgcg atcgtacttt tcgtaatcga ggaaagccgt taactccgtt
       61 ttgagaagcg tattgacagc tttttccaaa tggacacgga ataattcatt caaatcgcct
      121 ttgttcgcta gagtctttag aatttctgta gtaaaatcgt tcatatggaa gtcctctttt
      181 ctgtgaatgt gttgtggtaa ctctattcta cagaagggac ttcctttttt ctatttacac
      241 aaaatatttt acactctcac tcatttacac gttatttaat aagagaccac ggttaaataa
      301 aaatagatta tataaattat ataataagaa ggaattaaga gacatttcta atttattccg
      361 aaaagtgaaa acaaaaaata aatttctaaa aaaatataaa aaacatatca aattgatcga
      421 tgaaaatcta aaaacagatt gaaaatcttt tcatgcaaaa gatatgaaga aagctgttga
      481 taagggagac tatttctcta aattagccaa agacaataaa gtaaaagaag atagcgaaaa
      541 acggaaaagt gaagtttgat tcaactaata caacgattct ggtgacagtc aaagaagcat
      601 cttttaagtt gaaagacggc caaatttctg atgtgatcac ttctaccaat gattcaactt
      661 atgatccata aatactatgt aatcaaaaat ggtaaaaaat tagaataaag gcaacggaat
      721 ggataaatac taaaaacaat tgaaagaaat tactactgaa acgaaattga gcaacaatga
      781 atttcaaaat aaagtagtcg ataaaatatt gaaagacgct aatgtaaaaa ttaaagacaa
      841 aaattttgaa aattttttga gtatatttac ttcagatggt aaggcaacag aataaaatac
      901 aataggcaga tgaactaata aataaaatct gtattaaata cagataaatt aatataaaaa
      961 tcaagaggat cataaacttt taagagagga tgatccatta cttcatccat actcgataaa
     1021 ctagtgataa tgagctacac gtttttcttt caagttgatc aatagcttcc acgataaaaa
     1081 tatttttaga taaaatcaag aaccgtagga actacgggga tatttggtca ataagatcca
     1141 ccgctattag taaaaaataa gctatcaagt atgctctcat cccaagaatt gcctacttca
     1201 atcgttaaaa accgttaggt ttagctaag
//
LOCUS       DAPBCF010000162         1194 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.171, whole genome shotgun sequence.
ACCESSION   DAPBCF010000162 DAPBCF010000000
VERSION     DAPBCF010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.171"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..1076
                     /locus_tag="RD508_002982"
     CDS             <1..1076
                     /locus_tag="RD508_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDT7737479.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tctt
//
LOCUS       DAPBCF010000163         1190 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.172, whole genome shotgun sequence.
ACCESSION   DAPBCF010000163 DAPBCF010000000
VERSION     DAPBCF010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1190
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.172"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            143..400
                     /locus_tag="RD508_002983"
     CDS             143..400
                     /locus_tag="RD508_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737480.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(632..1063)
                     /locus_tag="RD508_002984"
     CDS             complement(632..1063)
                     /locus_tag="RD508_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HDT7737481.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          148 g          438 t
ORIGIN      
        1 ttttctgtcc acgttcattt tactccaaag ttttcctcat ttcaaaagaa aatcacagaa
       61 tacacgaaga agcgtttcta tttgtataaa ctatatcaaa gttctatact taaattatca
      121 aataaaaagg acgtgaagat aaatgtcaaa tttagaaaac aaagaagaaa aagttgtaaa
      181 caaaattgtt tctgttgtca ataaactgga taaagagtta gacgaacttg atacgttatc
      241 tgaaaatcca gaaaaaaaac ataacctaaa aaaatggtta gttgaacgaa aggctattca
      301 tgaaattaaa aaagttcttc atgaagctga taaatatgaa aaatatgatg aaaaagaact
      361 tgataaagaa tttaaagaaa tcaatgactt attactataa ttgatttata cgactcattt
      421 ttgagtcgtc agactgcaaa caacactcta aatttaggag tttgtctaca gtctgaataa
      481 attttaaatt tattgtccat aatgttatta tgaatttata gcattaagaa aagagataag
      541 actttacatt tttttaggaa tgtaaagtct tatctctttt cttaattgta caattagtat
      601 tatctgcact actttctaat taaataaatt tttagttatt aacttgatta aaatcagaga
      661 taatatcatt taattcagtt tgaagggttg taacgattaa atggaaattt tcttcatctg
      721 ttttattata tggggatgtt ttcgttatat ataacaactt ttctttttca attttcatta
      781 ataactctgt cgaagtctgt actttatctt gataattaaa tgcagacata ccactttgta
      841 taattgtaat tattgctgaa gcaattgaaa caatcaatag taaagacctg tgttcggaag
      901 cctgatcaat taatattggg atactagctg ataagactat ttttataata tttccgatac
      961 caattactct attataaaat cgaatttctt tttttaatct atcgattgta gaatcaatag
     1021 attcgataaa cgctttttga tccatcattt tctctccaat cattttatta aaatcattaa
     1081 caaaaatatt ataataggat ttaagtaagt tctaactaat cacatataaa aataaaaaaa
     1141 catttgtatt ttatcaaagt tttattatac ttgtcaattt gtgtacatcc
//
LOCUS       DAPBCF010000164         1175 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.173, whole genome shotgun sequence.
ACCESSION   DAPBCF010000164 DAPBCF010000000
VERSION     DAPBCF010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1175
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.173"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            66..>1175
                     /locus_tag="RD508_002985"
     CDS             66..>1175
                     /locus_tag="RD508_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HDT7737482.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREK"
BASE COUNT          386 a          221 c          231 g          337 t
ORIGIN      
        1 aacatatcgt tctctagtat gattaaatca cgacaaaata aacaactgag aggacgatat
       61 gctatatgaa tgattctatc aaaaaaatgc tgcgattaat agagaaagat ttgatgatta
      121 cagaggtctc ttacgagacc tttcagaaga aaaagacgtt gatcgtcgat gctgttttct
      181 cacctgctcc ccatacctgt agaaattgtg gttctactgt ggtagatgga aacgggaaag
      241 taattgtagt gaaaaatggg aagaaggaaa cgattgtccg ctttgaacaa tacaatcaca
      301 tgcctttggt tatgcgctta aaaaagcagc gctatacctg taaaaactgt cgaacccatt
      361 ggacggctca aagttatttt gttcaaccca gacattcaat cgcgaatcat gtcagatata
      421 aaattgcttc tttactgact gaaaaagtat ctttatcttt tattgcgaaa aattgtcagg
      481 tatctttgac caccgttatt cgtacgttga aagagtttaa aagctactta ccaaagcaat
      541 ctaagaggat tctccccaga gtattgatgg ttgatgaatt tcgttcgcac gcttccatag
      601 aagataaaat gagctttatt tgcgcagatg gcgaaacagg acaattaatt gatgtcttgc
      661 ctacgcgtaa attgcctcga ttaacaagct atttcttagg ctgcgctaat cctgaagaag
      721 taaaattttt agtcacagac atgaacgccg cctacttcca gcttaccaaa cgtattctgc
      781 caaatgcgaa agtagtgatt gatcggtttc atattatcaa acacatgaat caagccttta
      841 atgagttgcg tatccgtgaa atgaatgaac ttcgtaaagt aggacagaaa agtcaggcag
      901 aaaaactgaa aaagaactgg cgctttttgc taaaaaatcg tgcaaacatc aaccattatg
      961 aatacaaaac atggaaaagt tttcgagcac caaaataccc atttcttacg gaagcgatga
     1021 tgattgatcg attgcttggc ttttctacgt ccctgaagga ggcgtatccc tattttcatg
     1081 aattagttga agcctttcga gacaaagacc ctgacttatt tttctcctta ttggcagaac
     1141 ttcccgaaac gttagatgac ggctttcggg aaaag
//
LOCUS       DAPBCF010000165         1094 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.174, whole genome shotgun sequence.
ACCESSION   DAPBCF010000165 DAPBCF010000000
VERSION     DAPBCF010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.174"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..280
                     /locus_tag="RD508_002986"
     CDS             <1..280
                     /locus_tag="RD508_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDT7737483.1"
                     /translation="KRNPFVSEYVKRLAKGICQLCQEKGPFIKDGVPYLHCHHIEYLS
                     QGGKDVIENCIALCPNCHARIHELELPDDKEKLLKIVEKRENSFSKIP"
     gene            623..879
                     /locus_tag="RD508_002987"
                     /pseudo
     CDS             623..879
                     /locus_tag="RD508_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
BASE COUNT          379 a          164 c          198 g          353 t
ORIGIN      
        1 taaacgtaat cccttcgtat ctgaatatgt taaacgactt gcaaaaggta tttgtcaact
       61 ttgccaagaa aaagggccat ttataaaaga cggtgtacct tatttacatt gtcatcatat
      121 agaatatttg tcgcaaggtg gaaaagatgt gattgaaaac tgtatcgcgt tatgtcccaa
      181 ttgtcatgct agaattcatg aacttgagtt acctgacgat aaagaaaaat tgctgaagat
      241 cgttgaaaaa agagaaaata gcttttctaa aataccgtaa tttattttta taggacaaat
      301 aagctaatgt gagctatgcc ttctatataa gactaagttc tattataagt aacgaagtaa
      361 ttctcgttcc ttcctgtagt aatatttttt aaataaccta taggcttctt caaaagtaca
      421 tcctccagta aattctaagt actggaggat tctttttcta gtgttgcttt actcatgaaa
      481 aagtagttgg ctacttcatc aaaatttctg aactttttta atgtataata aagagctcga
      541 tcatttacta caaggatgct agctcctaca ttttcacagt tttttagcaa gtaaattttt
      601 ctaaaatcac atcaggaaat gcatgagatt ctttaagaaa ggcaattata gggctatgat
      661 tacggttcgt gtaagtgacg ccaaaaaaga atggctttct tatatggctg aattttatgg
      721 gattacttta tctgaacttc taaaaaacta ttcgatggaa caactagaag atgaatacaa
      781 tcgtcaaacg gctgaaattg cccataaaca ttggataaga agtgggaaaa caacagtatt
      841 catggaagaa tccttaatga atttggtggg ctggaatgac ctgccgttta aaattcacgc
      901 ccgaaattca gaagcagctc tgattggcaa atacgtgtat tggtagagat agaagataat
      961 caattcgttg ttaccgctat tcaagtaggg caccgaagaa atgtctatga ttaagagact
     1021 gtttattttt acaaaaaaat aataactgga atctagttaa aactcttgaa gtgagagatt
     1081 tgactagatt tttt
//
LOCUS       DAPBCF010000166         1091 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.175, whole genome shotgun sequence.
ACCESSION   DAPBCF010000166 DAPBCF010000000
VERSION     DAPBCF010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.175"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="RD508_002988"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="RD508_002988"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HDT7737484.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          384 a          135 c          187 g          385 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta a
//
LOCUS       DAPBCF010000167         1073 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.176, whole genome shotgun sequence.
ACCESSION   DAPBCF010000167 DAPBCF010000000
VERSION     DAPBCF010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.176"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..>1073
                     /locus_tag="RD508_002989"
     rRNA            <1..>1073
                     /locus_tag="RD508_002989"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          329 a          214 c          308 g          222 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaagagtgcg taatagctca ctagtcgagt gaccctgcgc cgaaaatgta
     1021 ccggggctaa acatattacc gaagctgtgg agtacacctt taggtgtatt ggt
//
LOCUS       DAPBCF010000168         1062 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.177, whole genome shotgun sequence.
ACCESSION   DAPBCF010000168 DAPBCF010000000
VERSION     DAPBCF010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.177"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(37..993)
                     /locus_tag="RD508_002990"
                     /pseudo
     CDS             complement(37..993)
                     /locus_tag="RD508_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          347 a          177 c          159 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcattcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgtc aa
//
LOCUS       DAPBCF010000169          994 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.179, whole genome shotgun sequence.
ACCESSION   DAPBCF010000169 DAPBCF010000000
VERSION     DAPBCF010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.179"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..>994)
                     /locus_tag="RD508_002991"
     rRNA            complement(<1..>994)
                     /locus_tag="RD508_002991"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          209 a          307 c          225 g          253 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatg
//
LOCUS       DAPBCF010000170          899 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.180, whole genome shotgun sequence.
ACCESSION   DAPBCF010000170 DAPBCF010000000
VERSION     DAPBCF010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..899
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.180"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..460
                     /locus_tag="RD508_002992"
     CDS             <1..460
                     /locus_tag="RD508_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7737485.1"
                     /translation="YPKAKYQHCCVHVSRNIAHKVRVKDRKEICDDFKAVYQASSKEE
                     ANTFLGSMIEKWQKTYPKVTQSLIKNQDLLTFYEFPPGIRRSIYSTNLIESFKKQIKK
                     YSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLASMFTE"
     gene            528..731
                     /locus_tag="RD508_002993"
                     /pseudo
     CDS             528..731
                     /locus_tag="RD508_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249826.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          337 a          159 c          136 g          267 t
ORIGIN      
        1 ttatcctaaa gctaaatacc aacattgctg tgttcacgtt tcccgtaata ttgctcataa
       61 agtacgtgtc aaagatcgaa aagaaatctg tgatgatttt aaggctgttt atcaagctag
      121 ctcaaaggaa gaggcaaata cctttttagg gagtatgatt gagaagtggc agaaaactta
      181 tcctaaagtg acgcagtcac tgataaaaaa tcaagattta ttgacttttt atgagtttcc
      241 gcctggtatc cgccgaagca tttactcaac taatttaatc gaatctttca agaaacaaat
      301 caagaaatac agccgcagaa aagagcagtt tcaaaatgaa gaatcactag agcgtttcct
      361 agtatccatc tttgatacat acaatcaaaa attcttaaat agaagccata aaggcttcca
      421 acaagtgacg gatacattag cttcaatgtt tactgagtaa cccattattt tgcagaagga
      481 cgtgttattt acacaaaatt attgacgctc ccattttctc atacagatta aataaataca
      541 aattagggat tcaatatgct ttaaaaacca agtatagtaa tggtgcatta gaaggaacaa
      601 ataacaagat aaaagtgata aagcgagtag cctatggcta tcgaaatttc cataactttc
      661 gagcaagact ttatctcatt caaggtttga tcatccaagt aaaacaaaaa ccagttaaac
      721 actttgccta actggttatg actaaatttt cagttgtatc tttctctacc aacactaaat
      781 gtcgatgaga caaaatcaag ttcattctgt ctcaaatcga ttttacacaa cccatcaata
      841 cttattggca aaaaaccaaa tatctaataa aaatatgctt aaataaaatt agtttttat
//
LOCUS       DAPBCF010000171          890 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.181, whole genome shotgun sequence.
ACCESSION   DAPBCF010000171 DAPBCF010000000
VERSION     DAPBCF010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.181"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            36..>890
                     /locus_tag="RD508_002994"
     CDS             36..>890
                     /locus_tag="RD508_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDT7737486.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLK"
BASE COUNT          261 a          174 c          178 g          277 t
ORIGIN      
        1 attaatttgg ctaccaattc ataggaggat tcaagatgtc tcatactcag cttatcaaag
       61 ataccctaaa tattctagac ctaaatatct atttcgagga aaattgttta actaaagaaa
      121 aatacaaagg gcaaatttgc ttgatttaca aaggaactct tctgtacaag ccagaagagt
      181 gttcccattg tctttgtgtc gtcccctcta ggatcattcg ttgggggacg acaaccgttc
      241 ggttgttact gaatgatgtg tctgagtatc gcacttatct ggagctgaag aaacaacgat
      301 ttaaatgtaa gtcttgccaa agaacattcg tagcggatac ctctgttgct gaaaaacact
      361 gtttcattag tcaaaaagtt cgttggtctg tcattgctcg cttaaaagag aatacttcca
      421 tgacggaaat cgctcgtcag aaaaatattt ccacttcttc ggtctatcgt gtcatgaagc
      481 gattctaccg cccattgaat cctttcaaac agactttgcc aaaggtctta tgctttgatg
      541 aattcaaatc ggttcgaagt gttgccagtg caatgagttt tatcatgatg gacggacaaa
      601 gccatgcatt attggatatt gtcgaaaatc gacgcttgcc ttatttagaa cgctattttt
      661 ctcggttttc attagcgact cgtgaagccg ttcaattgat tgttattgat atgtatgcgc
      721 cttatgtttc gttggtgaaa aagcttttcc cgaatgctca gttgatcatc gatcgtttcc
      781 acatcgtcca acatattggc agaactttct tgaatcatcg agtgaaagaa accacggtac
      841 gacttaaagg aaattcccac tctcaacgag ggttagggaa aaaattgaag
//
LOCUS       DAPBCF010000172          863 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.182, whole genome shotgun sequence.
ACCESSION   DAPBCF010000172 DAPBCF010000000
VERSION     DAPBCF010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.182"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..861
                     /locus_tag="RD508_002995"
     CDS             <1..861
                     /locus_tag="RD508_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HDT7737487.1"
                     /translation="EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPD
                     KYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKR
                     YKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIIS
                     YSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMS
                     RKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLS
                     PVEYRKQSIK"
BASE COUNT          374 a          112 c          140 g          237 t
ORIGIN      
        1 gagcaagaag aaatcaaggt taaaacaatc cttcagctca aaaaagaatt taaattgaat
       61 ctattacttt caattgcaca attagcgaag tcaacttatt attactgggt aaaaaaatta
      121 gataagccag ataaatatag caagataaag caagaaatta cagcgattgt aaaagaatca
      181 agaaactctt atggttatcg tagagtcact ttagcgttaa agatgaaagg atatacaatc
      241 aatcataaaa cagttagaaa attaatgtcc caaatgggac ttacctgtca aatccgaata
      301 aagcgatata aatcttataa aggaacagta ggaaaaattg ccaagaatgt gttaaaacga
      361 aatttttcag tagatacacc caataaaaaa tgggtgacag acgtcactga attcaagata
      421 aaaggaagaa aaatctatct atctcctata cttgatttat ttaacggaga aataattagt
      481 tatagtatat caactagtcc aacatataaa ctgattgaag aaatgcttca acaagcaatt
      541 aaaaaaaagg gaactgaggg ttcactgatt ctacattcag atcaaggatg gcagtatcag
      601 atgccacaat atcaaaaaaa attaaaagag aataacatta ttcaaagcat gtctagaaaa
      661 ggaaattgct tagataattc tgtaatagaa aatttttttg gtgtgcttaa atcagagttt
      721 ttttatcgag aaaaattccg atcaattgag atatttcaaa gtaaattaaa tgagtatatt
      781 aggtggtata ataacaaaag gataaaacta aagttaaatg gactatctcc agtagaatat
      841 cggaaacagt ccattaaata gtt
//
LOCUS       DAPBCF010000173          830 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.183, whole genome shotgun sequence.
ACCESSION   DAPBCF010000173 DAPBCF010000000
VERSION     DAPBCF010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.183"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..434)
                     /locus_tag="RD508_002996"
     CDS             complement(<1..434)
                     /locus_tag="RD508_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7737488.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHR"
     gene            complement(451..>830)
                     /gene="tnpA"
                     /locus_tag="RD508_002997"
     CDS             complement(451..>830)
                     /gene="tnpA"
                     /locus_tag="RD508_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HDT7737489.1"
                     /translation="VFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERISESYHITLVE
                     WNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKEMFWSKSFCL
                     LTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          250 a          136 c          133 g          311 t
ORIGIN      
        1 tgtctatgaa gcttaattct tactaatgac ttcaatttag gaactttgat gaatttacta
       61 tcaatcaaag caactgtacc attttgatta ttcgttgtat aactctgaac aggatttttc
      121 ttacttttga aacgtggaaa tccaacggat ttatcccgaa aaaaattctt gtatgcttta
      181 tctaaattaa gttgggcatt ggctaaagca aggctatcaa tttctttcaa aaacggaaat
      241 tctttcttgt atttagctgg tgtcggaaaa gtcatttttt tagaagaatc atttttaact
      301 tcttcatacg ccttttttcg gtcatcaagc attagattgt agaccttacg gacacaacca
      361 aaagatttgg caaagaagat ttcttgttcc tctgttggat agattctgaa tttgtatgct
      421 tttagttgtt ccataaagtt cacctacttt ctatttatga ttgtttcctt gattttggat
      481 atacttctta atcacatcaa ttggtgcgcc accagttgtc agaagacaaa aacttttaga
      541 ccagaacatt tctttccaaa gaaattgttt gactcttgga aagtcacgtt ttatcaatct
      601 tgagctggca cttttatagg cattgatgaa ttttgtcaat tctgttttag gttgagcttt
      661 gaacataata tgaacgtggt ctttatcatg attccactcc actaaagtaa tgtgatacga
      721 ttctgaaatt ctttcaaaag tagttttggc ataatcagat atttcatcat caatcacttg
      781 tctacgatat ttcgttacta aaacaaggtg gtaataaaga agaaatactg
//
LOCUS       DAPBCF010000174          817 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.184, whole genome shotgun sequence.
ACCESSION   DAPBCF010000174 DAPBCF010000000
VERSION     DAPBCF010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..817
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.184"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            156..485
                     /locus_tag="RD508_002998"
     CDS             156..485
                     /locus_tag="RD508_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7737490.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            475..762
                     /locus_tag="RD508_002999"
     CDS             475..762
                     /locus_tag="RD508_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDT7737491.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKTLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
BASE COUNT          303 a           93 c          162 g          259 t
ORIGIN      
        1 ccgggttgtt tataaggtag atgaagatga acacgtggtt gaaatttatt cagcaaggac
       61 gcattacgag tcacagtaat tacttgtaaa tacattatct cgtggtataa tgtatttact
      121 aagtaattac atactgttag aaatgaggga tttaaatgat tacaaaaaca agaaaacaag
      181 gcaattcaat catgttgaca gtacctaaag attttaatgt tcctaatgga gtcgaagttg
      241 aagcaaagtt ggtagagaat ggtattcttt atgaatttgt tgaaccacaa aaagaatttt
      301 atgattttag cgaagatatt ttgtctgata taattgcaga aggctacgat aaagatgaga
      361 ttcttgtaga atttaagaat agaaaaaaca aaatgcattc ttcctttaga gatattgctg
      421 aagatacact tactaattct aaagtaatga ctaaagagga gttggcaaca gaaattggct
      481 tatgaaatcg ttccttcaaa acatgtcatt aagtatttaa aaaagctaaa agagaagaca
      541 ttgaaagaaa aatttttgaa tttaatttat gatgaaattg cgattgatcc atataagggt
      601 gaacaaaaaa ctggggattt atcaggtatt tggtctagtg ggttcaaata tgcgggcaca
      661 acatatagag tagcttacga gattatagaa aacaaggtta ttccagtatt gttatgtgga
      721 acgcatgaaa acttttatga acagttgaaa aaattaatct agtgatttgt tgtcgttctt
      781 aagaaggacg gcttcttttt tatcgaagat ctgattc
//
LOCUS       DAPBCF010000175          789 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.185, whole genome shotgun sequence.
ACCESSION   DAPBCF010000175 DAPBCF010000000
VERSION     DAPBCF010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.185"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(150..>789)
                     /locus_tag="RD508_003000"
     CDS             complement(150..>789)
                     /locus_tag="RD508_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HDT7737492.1"
                     /translation="GVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQSFVQRGLFG
                     VKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVKDELKSIFKA
                     SELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRRRIRTTNVLE
                     RLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNSNNI"
BASE COUNT          238 a          181 c          137 g          233 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacct
//
LOCUS       DAPBCF010000176          786 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.186, whole genome shotgun sequence.
ACCESSION   DAPBCF010000176 DAPBCF010000000
VERSION     DAPBCF010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..786
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.186"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..693
                     /locus_tag="RD508_003001"
     CDS             <1..693
                     /locus_tag="RD508_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7737493.1"
                     /translation="ATISRHSSGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILS
                     DGQKIDNNKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEK
                     VMNQRTDFLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYK
                     ADWYGRKIIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINIL
                     TEGLRLHSMGLA"
BASE COUNT          290 a          119 c          146 g          231 t
ORIGIN      
        1 gctacaatat cacgtcattc tagcggtaaa tactatattt ctttgttgtg taaagaagaa
       61 attatcgaat tacctaaaac taattccaca attggtattg acttaggtat tatggacttt
      121 gcgattcttt ctgatggaca aaaaattgat aataataaat tcacgtccaa aatggaaaag
      181 aaactaaagc gtgaacaacg caaattgtct aggcgtgctt tattggctaa aaataaaggt
      241 accaatctat ttgaagctaa aaattatcaa aaacaaaaac gcaaagtagc tagattgcat
      301 gaaaaagtaa tgaatcaacg tactgatttt ctgaataagt tgagtacaga aatgatcaaa
      361 aatcacgata ttatctgtat tgaagactta aacacaaaag gtatgttgcg aaatcataaa
      421 ttagctaaaa gtatttctga tgtttcttgg tcaaagtttg tgactaaatt acaatacaag
      481 gctgactggt atggacgaaa aatcatcaaa gtagataaat ggtttccgtc tagtcagatt
      541 tgttcagagt gcggacataa agatggcaag aaatctcttg aaattcgaga atggacttgt
      601 cctgtttgtc atactcatca tgatcgtgat atcaatgcta gtatcaatat tctgaccgaa
      661 ggtctaagac tacattctat gggattggct tagatccaat catcaagaac cgtaggaact
      721 acggggatag cttggtaaat aagagacacc gctgttagta aagaaatacg ctatcaagta
      781 tgctct
//
LOCUS       DAPBCF010000177          749 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.187, whole genome shotgun sequence.
ACCESSION   DAPBCF010000177 DAPBCF010000000
VERSION     DAPBCF010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.187"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..699
                     /locus_tag="RD508_003002"
     CDS             <1..699
                     /locus_tag="RD508_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HDT7737494.1"
                     /translation="KALSKRGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAK
                     TTNVLNRKFLRDNPLEAIVTDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVL
                     VKKAFSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAVAES
                     TYKSLKVEFVYQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRI
                     LDNELGCANASEAV"
BASE COUNT          244 a          137 c          153 g          215 t
ORIGIN      
        1 aaagccttat caaaacgagg cattcagatc agccgacgaa aaattagtag aatcatgaaa
       61 aatagaggat taaaatcgag ctatactgtt gcttatttta aagtacatca ttctacttgc
      121 aatgaagcca aaacgacaaa cgtattgaat cgtaaattct taagagacaa cccattagaa
      181 gcgatcgtaa cagacttgac ttatgtacga gtcgggaaaa aatggaatta tgtctgtttc
      241 attttggatc tgttcaatcg agaaattctc ggctattctt gtggagaaca taaagatgcc
      301 gttctagtaa aaaaagcatt tagccgtatc aaacaacctc tgacagaggt tgagattttt
      361 catactgatc gtggaaaaga gtttgataac caagctattg atgaattatt aacaactttt
      421 gacatcaatc gatcattgag tcataaaggc tgtccttttg ataatgccgt agctgaatca
      481 acttataagt cgttgaaagt agaatttgtc tatcaataca catttgaaac cttacaacaa
      541 ttggatttgg agttatttga ctatgtcaat tggtggaacc accttcggtt gcacggtaca
      601 cttggctacg agacaccggt tggttaccgt aaccagagat tggcgcagcg aatccttgat
      661 aatgagctcg gatgtgctaa cgctagcgag gcagtctaac tttaactgtt agctcctgcc
      721 gaagatcgtc acatccgagg aggctcatt
//
LOCUS       DAPBCF010000178          748 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.188, whole genome shotgun sequence.
ACCESSION   DAPBCF010000178 DAPBCF010000000
VERSION     DAPBCF010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.188"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..>748
                     /locus_tag="RD508_003003"
     CDS             <1..>748
                     /locus_tag="RD508_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7737495.1"
                     /translation="VADFILNSGKTIIYSTMSDIKKNTKVGDATIIRFCQKIGFSGFS
                     DLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYSTIRLLDEEKLNEAIKMITQSK
                     NIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQAQVASLLTVNDLVIIFSLSGK
                     TKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQTAIEEFLNGGSLAGKISQLY
                     ICDLLVHGYEQNNNIDSVELREKVLRSIID"
BASE COUNT          274 a           99 c          121 g          254 t
ORIGIN      
        1 aagtcgctga ttttatttta aattctggga aaactattat ttatagtacg atgagtgata
       61 ttaagaaaaa cacaaaagtt ggcgatgcta ctattattcg cttttgtcaa aaaattggtt
      121 tttctggttt ttctgattta aaaattgaaa ttgcaaagga agactttagt caaaaaaaag
      181 aacatccgac tagtgtaaag tactatgatg aaattgctaa tagtttaaca gaagctctct
      241 attccactat taggctttta gacgaagaaa aattgaatga agccattaaa atgatcactc
      301 aatcaaaaaa catatatata tttggagtgg gatctagtgg aaatactagt cttgatttag
      361 aaaatatgtt tcttcgcgta ggagttcaag caaaagctgt actagaccct cattttcaag
      421 cccaagtcgc ttctttatta acagttaatg atttagtaat cattttttct ttatctggga
      481 aaacgaaaga tacttatgat tcattgaaaa tagctaaaaa aaatggcgca aaaattattg
      541 ctataactaa ctatattcat tcacctatag gaaagtctgc agacttagtt ttacaaacag
      601 ccattgaaga atttcttaat ggtggatctt tagctggaaa aatatcacaa ctttatattt
      661 gtgatctatt agttcatggt tatgaacaaa acaataatat tgattcagtt gaattaagag
      721 aaaaagtttt gcgctctatt attgataa
//
LOCUS       DAPBCF010000179          746 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.189, whole genome shotgun sequence.
ACCESSION   DAPBCF010000179 DAPBCF010000000
VERSION     DAPBCF010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.189"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..470)
                     /locus_tag="RD508_003004"
     CDS             complement(<1..470)
                     /locus_tag="RD508_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
                     /protein_id="HDT7737496.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELG"
BASE COUNT          239 a          134 c          109 g          264 t
ORIGIN      
        1 cctaactctt ctttaatacg ttcttggatc atttgagcga gcttcttcct tcgctgactt
       61 cgtgtttctt cagtcgtaaa aagattcagt gattttgtca cttttaaaat cgattcatcg
      121 atcgagtaaa tcagtagatc ttcatcagcc acatatcttc tgaaaatatt atttacctgc
      181 atatttcgct tgatatatag gttcatacgt ggtggaacaa cgtgtagtgt tttaggaaat
      241 ggttgtggta agtcacgtgg tctactcaca tttgtaatac cataccgctt ttttgcttca
      301 ggagaagaag ctaatatcaa tcctgaacca gtattatcag atcgactcat aacaacaagt
      361 tctgttgtta atggatctaa atttctttct atacattcga cacttgcgta aaagcttttc
      421 atatcgatta aaaagtaatc atttactggc tcttttgaat aatccatcat aaataacact
      481 ccattcttcc acattataca aacatatgtt cgatgttgta aagaagaaat agctaaatac
      541 ataaaaaaag aagcataggt atgctatcac cctgcttctt cttatgattt gtatgatcaa
      601 tttattctat cactttacta attaatttga aaatctaata aaaactctca ctctaaaaga
      661 gtgagagact gcaaattaga gtacggactt ttttggagtt ccgttcttta atattaacaa
      721 atgaataaaa tccttacaac atttga
//
LOCUS       DAPBCF010000180          731 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.190, whole genome shotgun sequence.
ACCESSION   DAPBCF010000180 DAPBCF010000000
VERSION     DAPBCF010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.190"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..>731)
                     /locus_tag="RD508_003005"
     CDS             complement(<1..>731)
                     /locus_tag="RD508_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator BglG"
                     /protein_id="HDT7737497.1"
                     /translation="VQHLVHHIDKDSFLSMSRKLMIQMFRKVWVSVLGKTYGLTTSGP
                     VAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQFLEHLPPLSEKDENFLRLL
                     IVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCGNYVFEALDMPVESNVSEIV
                     ESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGELLLLNNLTTSIALDIGLKM
                     TMNAPFKQIAEDAADKYSINVQYFEG"
BASE COUNT          215 a          167 c          124 g          225 t
ORIGIN      
        1 ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc aatctgttta
       61 aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt cgtcaaatta
      121 ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat ttgatttaaa
      181 gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt cacgaaattc
      241 cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa cgcttcaaaa
      301 acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt actatctccg
      361 tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga taaagtcacg
      421 acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa atgctccaag
      481 aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg atttatcccg
      541 gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat ttctgcaaca
      601 ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac ctttctaaac
      661 atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat gtgatgcacc
      721 aaatgctgta c
//
LOCUS       DAPBCF010000181          716 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.191, whole genome shotgun sequence.
ACCESSION   DAPBCF010000181 DAPBCF010000000
VERSION     DAPBCF010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..716
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.191"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
BASE COUNT          303 a           80 c           92 g          241 t
ORIGIN      
        1 aaagcaacta gaagctactg atttagtatt tacaaatata aactatattg ctaacaatta
       61 ttttctagaa ggaataaaag aactaagaat caagacgtta tcttgattct tagttctttt
      121 aacatggaaa agatggataa tgcactgtta attcatgatg catcatcaga aaagttggaa
      181 ggagaagata gaaatcatta aatgatttct acagatggta aatgaaaaaa caaaatatta
      241 gcaaaaattt gcctaaatag atagtaacac tttctaaatt aaatacaagc gcattcataa
      301 aatgtttata caaatatcta tgtgataaaa attggatatg ttcacaataa ataggaatta
      361 aaataacgaa tttacgtttg tttttattta ccaatcaaat tatcttaatg caggaataaa
      421 aaattaaatt acatattgtt aatcatttac atctccatta ataactcaaa atgaaaagat
      481 gtttttattt ttattctata tttcagaaaa aaattaaact agattataat aattcttcat
      541 gtaaaaataa aaacaattac agctatgatg tttaagataa aacaattatg aaatcgatat
      601 ccgtttatat acttatcata agctagaagc aaataactag cctatgtatg taagtgagat
      661 tatatttatt aaaaggcttc ttttgttcga tcagttatag tcgaacgaga gaagtt
//
LOCUS       DAPBCF010000182          713 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.192, whole genome shotgun sequence.
ACCESSION   DAPBCF010000182 DAPBCF010000000
VERSION     DAPBCF010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..713
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.192"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(104..553)
                     /locus_tag="RD508_003006"
                     /pseudo
     CDS             complement(104..553)
                     /locus_tag="RD508_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611666.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            complement(608..>713)
                     /locus_tag="RD508_003007"
     CDS             complement(608..>713)
                     /locus_tag="RD508_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7737498.1"
                     /translation="MKAIRGLYKKTRKEGALFGFSVCTEIKVLLGIPA"
BASE COUNT          219 a          117 c          116 g          261 t
ORIGIN      
        1 aaacctataa ttcaaatagg aagccttgcg tattatttaa gatggttctg ttgcaaagtt
       61 aaaaaattaa taaagagttt ccaattaatt tttgatttta tgcttagata ctcattaatg
      121 tattcatctc atgaatcact gaaaagccaa agagactttt gtctctttgg ctaattttat
      181 ataaagcgtg tatagtttca attcctttaa ttgttgagga atcagtcctt atggactgat
      241 ataatttgtg ccttttcttg atggatcgat gatcctgttc aatgatatta ttcaagtatt
      301 tatttgttcg gtgttcagtc ttagaaaata atccttcaga atgcaattga ttaaacgcac
      361 tacttagtga aggggcttta tcagtgacaa gaactttagg ttctccaaat tgtttgacca
      421 atcgtttaaa gaaagcataa gctgcttgtt tatcacgctt ttttcgtaac caaatatcta
      481 atgttatccc cgaagaatca atggatcgat acaaatagtg ccactttcct tttaccttaa
      541 tataagtttc atcggttctg ttgcaaagtt ttaaataaag aataaaatct cttacggtat
      601 ctatgattta agctgggatt cccaataata ccttgatttc agtacagacc gaaaacccga
      661 agagagcgcc ttcttttcgg gttttcttat ataatcctcg aatggctttc atg
//
LOCUS       DAPBCF010000183          710 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.193, whole genome shotgun sequence.
ACCESSION   DAPBCF010000183 DAPBCF010000000
VERSION     DAPBCF010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..710
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.193"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..354
                     /locus_tag="RD508_003008"
     CDS             <1..354
                     /locus_tag="RD508_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDT7737499.1"
                     /translation="TQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVD
                     QEMYKQAQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISI
                     LKELEEHENWYAEVE"
     gene            355..>710
                     /locus_tag="RD508_003009"
     CDS             355..>710
                     /locus_tag="RD508_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737500.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIK"
BASE COUNT          281 a          100 c          152 g          177 t
ORIGIN      
        1 acccaagtaa aatcgatgag aaatgcgatg caatatcttg agtatatgga cttttttgtg
       61 aaagaatttg atacaaattt atatgttgct ggtgttattc ctttcatgtt ggaaagcggt
      121 gacgcagtag atcaggaaat gtataaacaa gcccaagaga tttatgggga acatttgatt
      181 aaaaatgttg tactcaaaaa tgcgcgctta aaacgatacg acggatcagg tattacgatg
      241 gagaagacaa agaaaggtct cttaaaacaa tgggatcgca aaagccacga attatttatc
      301 agtattttga aagaattgga agaacacgag aattggtatg cggaggtgga gtaattggct
      361 gacatcaaag gacttgatat ttttgggaac aacaaaggac tcgccaaaat aaaaaaagaa
      421 gcagaagcaa agaaaaagca gcaagcaatt acaccatctg aaaataagca attagaagtg
      481 caccaagttc aagaaataaa aacttcctcc aatgttgaaa gacagagtag aggaagaaca
      541 aaaaaagttg gcgcaccaat cagaaagttt gataaggttt attccaccaa gcatccttta
      601 aaactgtcga ctttgttaaa tgcgacttcc agagttttag tagaaaagta tgagactaat
      661 atgacaagag atgaattgct tagaaaagct ttagatgagt atattaaaca
//
LOCUS       DAPBCF010000184          671 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.195, whole genome shotgun sequence.
ACCESSION   DAPBCF010000184 DAPBCF010000000
VERSION     DAPBCF010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..671
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.195"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..666
                     /locus_tag="RD508_003010"
     CDS             <1..666
                     /locus_tag="RD508_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7737501.1"
                     /translation="MYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWL
                     YVIHAFLDGLSFYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWA
                     FIYFFVFTFFIKKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIES
                     VEACATRLRVAVTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILG
                     KDN"
BASE COUNT          210 a           87 c          135 g          239 t
ORIGIN      
        1 atgtatcgtg caattcctaa gaaaaatcgt aaaaagaatg gtgggcttta ttttagcggg
       61 gcccttacat catttttaac tggaattact gaaccagttg aatatatgtt tttatttgtt
      121 gctccttggc tttatgtgat tcatgcattc ttagatggat tatcttttta ttttgctgat
      181 atcttaaata ttcgtgtagg gaattccttt tcaggtggtt tgatcgactt tttattattc
      241 ggtgtacttc aagggaatga caaaactaat tggttaaaat taattccttt tggtattgca
      301 tgggcattta tatatttctt tgtttttaca ttctttatca aaaaatttaa ggtagctatt
      361 cctggaatgg aagaagaatc agaagttcat tctgaaaaag taataaacaa aaatacatca
      421 ttacatgaag agtctcttat cattattgaa gctcttggtg gaaaagaaaa tattgagtct
      481 gttgaagctt gtgcaactcg tttgcgtgtt gctgttacga atggggagat tattcaaaaa
      541 caaacaataa aagacactgg tgcaactgct gtcttcgaag tgaagggtgg catccaagct
      601 gtttttggag ggaaagctga cttattaagt caagaaatca atcaaatatt aggaaaagat
      661 aattaggagg t
//
LOCUS       DAPBCF010000185          661 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.196, whole genome shotgun sequence.
ACCESSION   DAPBCF010000185 DAPBCF010000000
VERSION     DAPBCF010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.196"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..>661
                     /locus_tag="RD508_003011"
     CDS             <1..>661
                     /locus_tag="RD508_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HDT7737502.1"
                     /translation="KAGFVTEDNLYLDSTHIKANANKHKFTKEMTHDEAKAYQDELED
                     EINRQRIEAGKRPFTLDLEKEVKLKERKISKADPESGYYVKGEREKQFAYSAHTSCDD
                     NGFILSTIITPGNIHDSQVAFQLVKQSKRLFPEINCVVADAGYKTPKFVHFLTHLNLR
                     PCLPYSRPKGKKGLLSKNEFLYDEYFDCYICPQDQMLAFSTVTREGYREYKSNPKECV
                     NC"
BASE COUNT          224 a          125 c          133 g          179 t
ORIGIN      
        1 aaagcaggtt ttgtaacaga ggataatttg tatctggatt ctacccacat caaagctaac
       61 gccaataaac ataagtttac gaaagaaatg acccatgatg aagcgaaagc ctatcaggat
      121 gaattagaag atgagatcaa tcgtcaacga atagaggctg gaaaacgccc ttttactttg
      181 gacttagaaa aggaagtgaa gctgaaagaa agaaaaataa gtaaagctga tccggaaagc
      241 ggctactacg tcaaaggcga acgagaaaaa caatttgctt attctgccca tacttcatgc
      301 gacgacaatg gatttattct tagcacaatc atcactcctg gaaatattca tgacagtcaa
      361 gtcgcctttc agctcgtcaa acaatcgaag agactttttc ctgaaatcaa ttgtgttgtc
      421 gctgatgctg ggtataagac acctaagttt gttcactttt tgactcattt gaaccttcga
      481 ccttgtttgc cttattcaag gcccaaaggg aaaaaggggc tattatcaaa aaatgagttt
      541 ctctatgacg agtattttga ttgttatatt tgtccgcaag atcaaatgct cgctttttca
      601 acggttactc gagaagggta ccgagaatac aaatccaatc caaaagaatg tgtgaactgt
      661 c
//
LOCUS       DAPBCF010000186          640 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.197, whole genome shotgun sequence.
ACCESSION   DAPBCF010000186 DAPBCF010000000
VERSION     DAPBCF010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.197"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..283
                     /locus_tag="RD508_003012"
     CDS             <1..283
                     /locus_tag="RD508_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7737503.1"
                     /translation="LIQDDLHHTHRLWLMNKINLYFGHSYVFAFYDYRTNITEVDLVI
                     SNYYIDTGKTPLLLMKNIPTERNWRLFEKTIYQLKKEKEVVKSAFCPEY"
BASE COUNT          218 a           89 c          119 g          214 t
ORIGIN      
        1 tttaatacaa gatgatttac accatacgca tcggttatgg ttaatgaata aaattaatct
       61 gtattttggg cattcttatg tttttgcttt ttatgattac aggacaaata taactgaagt
      121 agatttggtt atttctaatt actacatcga cactggaaaa acgccattac tgttaatgaa
      181 aaatatacct accgaaagaa actggcgttt gttcgagaaa acgatttatc aattgaaaaa
      241 agaaaaagag gttgtgaaat cagcgttttg tcctgagtat tagagaaaca aacggaaaaa
      301 tagtttttca tattttgccg tttttgagct aataccgagg gacagctgat tgaacaccat
      361 ttattgagag attgtgaaaa aactgtcctg catcaagtaa taagaacagc caagtaaaaa
      421 cagcttctca tgtttgttga atattgtgac ttgtgaccga ggagttggca agagaacacc
      481 gtttattcgg aaaaagggac tgtgacacta catgtcacag tccctttttg attgaattat
      541 ctcatttgtt ttctaatttt ttctttattt gagaaaatag ttgaactgga taaaaagtac
      601 tggacgtgtc aaaattattt tggatcaaat tagatctatt
//
LOCUS       DAPBCF010000187          635 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.198, whole genome shotgun sequence.
ACCESSION   DAPBCF010000187 DAPBCF010000000
VERSION     DAPBCF010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.198"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..>635
                     /locus_tag="RD508_003013"
     CDS             <1..>635
                     /locus_tag="RD508_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
                     /protein_id="HDT7737504.1"
                     /translation="AKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRM
                     KKRLNQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSY
                     GNSQVLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSH
                     QMKIPITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLF"
BASE COUNT          222 a          106 c          144 g          163 t
ORIGIN      
        1 tggctaaact agccttagac aacgaagcaa agcataatga aggatttgtt gcggaatgga
       61 cgtacgaaaa cgttcctgaa aaagtatgga atattcctga aatgacggac ttttggggaa
      121 ttggctctcg aatgaaaaaa agactcaatc agatggggat tatgagcatt agagatcttg
      181 ctaactggaa tccttatacg attaagaata gactaggtgt gattggctta cagctgtact
      241 tccatgctaa tgggatcgat cgaacagata tagcaatccc accagaaccg acaaaggaaa
      301 aatcatatgg aaattcacaa gtgttaccac gagattatac tagaagaaat gaaatcgagc
      361 tggtggtaaa agaaatggcg gaacaagtag cgatacgcat taggcagcat aactgtaaaa
      421 caggttgtgt ccatttacac attggcacgt cgatcttaga aacgagacca gggttttcac
      481 accagatgaa gatccctatc acagataata caaaggaatt gcagaattat tgtcttttct
      541 tgtttgataa gtattatgaa ggacaagaag taaggcatgt tggaataacc tatagcaagc
      601 ttgtgtacac cgattcgctt cagctggatt tattt
//
LOCUS       DAPBCF010000188          621 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.199, whole genome shotgun sequence.
ACCESSION   DAPBCF010000188 DAPBCF010000000
VERSION     DAPBCF010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.199"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            162..272
                     /locus_tag="RD508_003014"
                     /pseudo
     CDS             162..272
                     /locus_tag="RD508_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(378..>621)
                     /locus_tag="RD508_003015"
     CDS             complement(378..>621)
                     /locus_tag="RD508_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7737505.1"
                     /translation="EDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGPLEC
                     LNNHIKVLKRNVYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          200 a           92 c          107 g          222 t
ORIGIN      
        1 acatctttca gcattttact atatttggta tatagttcta aggttcatat tcgattgaca
       61 agagaatata aattgatcta tttctatttc ctaagttgag taaacataac tttgcccttt
      121 ataaatatct tccctctctc tcttctctct atattttata tttgaataat catatcaagg
      181 tattccaacg aaatgccaat ggatttcgaa gcttttataa ctttaaatta cggatcatga
      241 tttggcatgg ggaatcatta ctaataaaat aaaaaaatga acagaaagaa aaggctcttt
      301 gtcaaatgat gttggtaaag agaaatctta gaataatttg gacagaacag aaagaagaaa
      361 acctctttct gttctgttta tttggttaaa aatgttttgc catgacgaat cataattcgt
      421 agtttgaaat tgtaaaagtt gcgaaagccg tacacattgc gttttaatac tttgatgtgg
      481 ttgtttaagc attccaatgg tccgtttgaa tagctgtagt gaagcgcatt ttggatctgt
      541 ggcagaaact ttttaaacgt tcgtaaagtg gttgtatagg tttctggcag accgctaatg
      601 tctctagtta aacaatcctc a
//
LOCUS       DAPBCF010000189          556 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.200, whole genome shotgun sequence.
ACCESSION   DAPBCF010000189 DAPBCF010000000
VERSION     DAPBCF010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.200"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..163
                     /locus_tag="RD508_003016"
     CDS             <1..163
                     /locus_tag="RD508_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7737506.1"
                     /translation="GLPKSMDFREVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYV
                     QEAFYSSLI"
BASE COUNT          229 a           79 c           64 g          184 t
ORIGIN      
        1 tggactgccg aaatcaatgg attttagaga agtgaatcag acatttattt ccagtgtcag
       61 caatcaacgt aatcatattc caagaaaatc attgaattac agaacaccaa tcgaaatatt
      121 tttgagctat gtacaagaag cattttattc tagcttaatt tgacaaatca tacaaacaaa
      181 aataaataaa gtcggatttt tctgataatt caacgcaaaa aaacgaacaa tttttcaata
      241 aatcagtctt ctaaaataga taacctaaaa aaaacgaaca aacaaataaa atgactgtcc
      301 ttcattcact aaacatattt ttatttttta tattgttaaa aattcacaat tattttttaa
      361 tagaattatc tgttttccaa attttataac ataaaaaacc ttttttaacg gcatttatat
      421 gctttttcag aaattaactg atgatttcaa aaagaaaaca tgtcataata tttcccatat
      481 tgtgcaaaaa aatacaaggt ggaggctcta ctatgattga agaatatatt gagaaaaata
      541 ttttaagaca gctgtt
//
LOCUS       DAPBCF010000190          549 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.201, whole genome shotgun sequence.
ACCESSION   DAPBCF010000190 DAPBCF010000000
VERSION     DAPBCF010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..549
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.201"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..341)
                     /locus_tag="RD508_003017"
     CDS             complement(<1..341)
                     /locus_tag="RD508_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7737507.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWI"
BASE COUNT          173 a          106 c           73 g          197 t
ORIGIN      
        1 ttgatccaat catcatacat ttcaaaggac atgtctgctg gaagtatata gaggttattg
       61 attactttat agacagcctc tttaggtgga agattgttta tcaacacgtc agtcacagta
      121 ttttcgtaaa caatcggttc accttctccg cctccttctt cgttagtgaa gttcatatgc
      181 gttaagttca tcacatcaga agtatttcct tgcatatcca agtcaattat caaggttctt
      241 tttccttcat taactgctga ttcaaaccct aacatttgcg cgcacgtact tttacctacg
      301 ccacctttaa aattaccgat tacatatttc ttcgctacca cgttcctacc tcttttcttt
      361 tagcaatatt catttgatac tattataaca tatttatttt tagttactac caaaaaaaag
      421 atatatatgt actaccttat aattaataag taaaaggtag tacataaata aggaaaagct
      481 gaaatatatt gatttatagc tttcctcaaa gtaatgacgt tatttaattt atcgagaagc
      541 agagaatac
//
LOCUS       DAPBCF010000191          548 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.202, whole genome shotgun sequence.
ACCESSION   DAPBCF010000191 DAPBCF010000000
VERSION     DAPBCF010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.202"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..>548)
                     /locus_tag="RD508_003018"
     CDS             complement(<1..>548)
                     /locus_tag="RD508_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDT7737508.1"
                     /translation="SLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW
                     ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPT
                     IFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG
                     NDDLLEKYMSGKSLEALELEQE"
BASE COUNT          147 a          119 c           84 g          198 t
ORIGIN      
        1 tcctcttgtt cgagttccaa tgcttctaat gatttaccgg acatatattt ctctaaaagg
       61 tcatcgtttc cctctattac cgtatcccat tgttcagatt cggtaaagtt cgtcacacac
      121 atattaggat acagttctac cttctgtttg attacaattt cggcagaaag tttctcttta
      181 atatcctgat aaaccgttga taaatcaatt ccattttggt caatcttatt gataaaaaag
      241 attgtgggaa tccccatttt cctaagtgca tgaaataata tacgagtttg tgcttgtacg
      301 ccatcttttg cagaaatcag tagaattgcc ccatctaaaa ctgataatga acgatatact
      361 tctgctaaga aatccatatg tcctggcgtg tctatgatgt tcaccttcgt attttcccac
      421 tgaaaagagg ttattcctgt ctgaattgta attcctctct gacgttctaa aagcgtatta
      481 tccgtcctcg ttgtaccttt gtccacgctt cctaattctg taatcgctcc actgttatat
      541 aataagct
//
LOCUS       DAPBCF010000192          542 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.203, whole genome shotgun sequence.
ACCESSION   DAPBCF010000192 DAPBCF010000000
VERSION     DAPBCF010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.203"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..396
                     /locus_tag="RD508_003019"
     CDS             <1..396
                     /locus_tag="RD508_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7737509.1"
                     /translation="VTYSITDPSVHDVKVLETLSEEANLPNILGDKGYVSHKIHEKLA
                     LKGITVLVPSRKNMDKLGKIDHRLLTRQRKAVETVFSSLERLGFQNFKSRSIQGLESK
                     FESILLSYSILLSRAQQHFEGTLRYSLGY"
BASE COUNT          197 a           82 c           94 g          169 t
ORIGIN      
        1 gttacttatt caatcacgga tcctagtgtt catgatgtga aagttttaga gactttatcg
       61 gaagaagcaa accttccaaa tatccttgga gataaaggct atgtcagcca taaaatccat
      121 gaaaagcttg cccttaaggg cattacagtc ttagttccgt cacgaaaaaa catggataaa
      181 ctagggaaga tagaccatcg attacttact agacaaagaa aagcagtaga aactgttttt
      241 tcttctctcg aaagactagg ttttcaaaat ttcaaatcac gttctattca agggctagaa
      301 agtaagtttg aaagcatatt attatcgtac agtattcttt taagccgagc acagcaacat
      361 tttgaaggga ctttgagata ttctttaggg tattaaaatt aactagcacc acgggtatac
      421 tactatattt taggtttcat attatataaa ttaataatat actaccattt gttggtagta
      481 taatttaaag agagtgtaaa atattttgtg taaatgaaaa aatccataca aaaaaggaag
      541 tc
//
LOCUS       DAPBCF010000193          525 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.204, whole genome shotgun sequence.
ACCESSION   DAPBCF010000193 DAPBCF010000000
VERSION     DAPBCF010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..525
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.204"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..462
                     /locus_tag="RD508_003020"
     CDS             <1..462
                     /locus_tag="RD508_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7737510.1"
                     /translation="KKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVIPDGSK
                     IYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQENDEVTPE
                     TSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
BASE COUNT          190 a           69 c           93 g          173 t
ORIGIN      
        1 aaaaagaaaa aacaagaaac tttttatgca ccttgttccg gaaaaatcat ttccatcaca
       61 gaagtaaatg atcctgtctt ttcacaaaaa ttactaggtg atggttttgc cgtcatacct
      121 gatggttcaa aaatttatgc tccattggct ggtcgagtaa caaatatatt tcctactaaa
      181 catgctatta atataaaaag caactcaggc attgattatt tgattcatat tggaattgat
      241 acagttgaat tacaaggaga gcctttttcg atttgtgttc aagaaaatga tgaggttact
      301 cctgaaacct cgttggttga tgtggatttt gacaaaataa taaaatctgg taaagatact
      361 tctgttatag ttgtttttcc ggagaaaaat cagttcaatg atttaataat agataatggt
      421 cgaattgctc atgggaattc atgtggaaaa atcacttttt aaaaaagtgt atataaaaag
      481 ctataaaata agctaaatag gatatttgtc aaatgaagtt ggtga
//
LOCUS       DAPBCF010000194          513 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.205, whole genome shotgun sequence.
ACCESSION   DAPBCF010000194 DAPBCF010000000
VERSION     DAPBCF010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.205"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            17..>513
                     /locus_tag="RD508_003021"
     CDS             17..>513
                     /locus_tag="RD508_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HDT7737511.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          187 a           93 c           85 g          148 t
ORIGIN      
        1 aaaagaggac ttccctatga atgattttac tacagaaatt gtgcaaactc tagtcactaa
       61 aggcgattta aatgaattat tccgttcgca cttagaaaaa gcgataaaca cactcctacg
      121 gactgaatta acggcttttt tagattacga aaaatatgat cgcactggtt ttaattcagg
      181 taattcgaga aacggttctt actttcgatc aatcaaaacc gaatatggtg aattaacatt
      241 ggaaatacct agagatcgta atggtgagtt taaacaacaa actttaccag cctacaaaag
      301 aacaaacgat acattggaaa ccactattat ccatttattc gaaaaaggtg ttacgatgtc
      361 tgaaattgct gatttgatcg aaaaaatgta cggtcatcac tatactccac aaaccatgtc
      421 caacatgact aaagttctga ctgaagaagt aaatgccttt aaatccagag ccttaaatga
      481 taagtatgtc gctattttta tggacgctac tta
//
LOCUS       DAPBCF010000195          512 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.206, whole genome shotgun sequence.
ACCESSION   DAPBCF010000195 DAPBCF010000000
VERSION     DAPBCF010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.206"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            13..>512
                     /locus_tag="RD508_003022"
     CDS             13..>512
                     /locus_tag="RD508_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7737512.1"
                     /translation="MNRSRQTIHKVYLFFKQGKSALEYYQQYKKNKSNCGRRPLVLPE
                     EQSEYIQRKVVQGWTPDVIVGRAAFPISCSARTIYRMFKKGLFDSSDLPMKGKRKPNG
                     HQERRGKQTFRRSIHEREKDYSQFSNEFGHLEGDTIVGLKHKSAVITLVERLSKVIIT
                     LKPCGR"
BASE COUNT          170 a           96 c          103 g          143 t
ORIGIN      
        1 actgcccatt gcttgaatcg ttcaagacaa acgatccata aagtatatct gttcttcaag
       61 caaggaaaat cagccttaga atattatcaa cagtataaga aaaacaaatc aaactgtggt
      121 agacgtccgc ttgttttacc cgaggaacaa tcagaatata ttcaaagaaa ggttgttcaa
      181 ggatggacac ccgatgtgat tgttggtcgt gcagcgtttc ctattagttg ttctgctcgt
      241 accatttatc gtatgttcaa aaaggggcta tttgattctt ctgacttacc gatgaaaggc
      301 aagcgtaaac cgaatggaca tcaagaaaga cgtggaaaac aaactttccg ccgctctatt
      361 catgaacgtg aaaaggatta tagccaattc tcaaatgagt ttggtcacct tgaaggtgac
      421 actatcgtag gtctgaaaca taaaagtgct gtaattacct tagttgaacg attatcaaaa
      481 gttatcatca cattgaaacc gtgtggtaga ca
//
LOCUS       DAPBCF010000196          489 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.207, whole genome shotgun sequence.
ACCESSION   DAPBCF010000196 DAPBCF010000000
VERSION     DAPBCF010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.207"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            1..489
                     /locus_tag="RD508_003023"
                     /pseudo
     CDS             1..489
                     /locus_tag="RD508_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          180 a           93 c          107 g          109 t
ORIGIN      
        1 caagtgaagc gctggatcaa tgcctatcaa gaatttggtg aagagggtct agtaagaaag
       61 cgacaaaaga aaaaatattc tgttcaattt aagctggatg cgatagagtt atatctaaca
      121 agtgagctgt cctatcgtga agttgccaac acacttaaca tgaacaaccc taatttgatc
      181 gctagttgga tgcgtcaatt ccgtgagggt gggatcgatg gactctcaaa aacgaaagga
      241 tgtccaccta tcttgtctaa gaaaaatgaa cccaaaaata agaaaaaatc tacaactaaa
      301 gcaacgtcta aagaacgtga acgcatcgag gagttggaga aacgagtccg ttcccttcaa
      361 attgaaaatg cctttttaaa agaattgagg aagctgcgaa aacaggaagc ccaacaacga
      421 cgaatgaagc aatcgcacga atcatcgcaa gcctccgagg accgtttaaa ttagttgagc
      481 ttctagaaa
//
LOCUS       DAPBCF010000197          440 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.208, whole genome shotgun sequence.
ACCESSION   DAPBCF010000197 DAPBCF010000000
VERSION     DAPBCF010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.208"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            11..>440
                     /locus_tag="RD508_003024"
     CDS             11..>440
                     /locus_tag="RD508_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDT7737513.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          168 a           57 c           88 g          127 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag
//
LOCUS       DAPBCF010000198          435 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.denovo.209, whole genome shotgun sequence.
ACCESSION   DAPBCF010000198 DAPBCF010000000
VERSION     DAPBCF010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.denovo.209"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..>435
                     /locus_tag="RD508_003025"
     CDS             <1..>435
                     /locus_tag="RD508_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7737514.1"
                     /translation="YLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDIW
                     LRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVKY
                     LNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKN"
BASE COUNT          153 a           84 c           85 g          113 t
ORIGIN      
        1 attatctttg gaagaagaaa aatagacaat ccttctattc atggaaaatg gacgaaacct
       61 atatcaaaat taagggacgt tggcattatc tttatcgtgc aattgatgcg gacggcttaa
      121 ccttagatat ctggttacga aagaaacggg atacgcaagc agcctatgct ttcttaaaac
      181 gactccataa acagtttggt gagccgaaag caattgtgac cgataaagca ccttctcttg
      241 gctccgcctt tagaaagtta cagagtgtgg gtttatatac taagacagag caccgaactg
      301 tgaagtatct taacaattta atagaacaag accatcgacc tattaaacga cgaaataaat
      361 tttatcaaag tctccgtaca gcctcttcca cgattaaggg catggagacc attcgaggaa
      421 tatataaaaa gaacc
//
LOCUS       DAPBCF010000199        23728 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.guided.039, whole genome shotgun sequence.
ACCESSION   DAPBCF010000199 DAPBCF010000000
VERSION     DAPBCF010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.guided.039"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..212
                     /locus_tag="RD508_003026"
     CDS             <1..212
                     /locus_tag="RD508_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDT7737515.1"
                     /translation="ELEQEESIRFQNCSLFPLYHGSAKSNIGIDNLIEVITNKFYSST
                     HRGPSELCGNVFKIEYTKKRQRLAY"
     gene            447..683
                     /locus_tag="RD508_003027"
     CDS             447..683
                     /locus_tag="RD508_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737516.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            690..2642
                     /locus_tag="RD508_003028"
     CDS             690..2642
                     /locus_tag="RD508_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HDT7737517.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2714..3211)
                     /gene="dfrG"
                     /locus_tag="RD508_003029"
     CDS             complement(2714..3211)
                     /gene="dfrG"
                     /locus_tag="RD508_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HDT7737518.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3573..4613
                     /locus_tag="RD508_003030"
     CDS             3573..4613
                     /locus_tag="RD508_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDT7737519.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            4711..4899
                     /locus_tag="RD508_003031"
     CDS             4711..4899
                     /locus_tag="RD508_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HDT7737520.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(4957..5310)
                     /locus_tag="RD508_003032"
     CDS             complement(4957..5310)
                     /locus_tag="RD508_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7737521.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            5841..6263
                     /locus_tag="RD508_003033"
     CDS             5841..6263
                     /locus_tag="RD508_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7737522.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            6260..6490
                     /locus_tag="RD508_003034"
     CDS             6260..6490
                     /locus_tag="RD508_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7737523.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            6988..7188
                     /locus_tag="RD508_003035"
     CDS             6988..7188
                     /locus_tag="RD508_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HDT7737524.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            7215..8408
                     /locus_tag="RD508_003036"
     CDS             7215..8408
                     /locus_tag="RD508_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7737525.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(8476..10041)
                     /gene="guaA"
                     /locus_tag="RD508_003037"
     CDS             complement(8476..10041)
                     /gene="guaA"
                     /locus_tag="RD508_003037"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDT7737526.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(10100..11023)
                     /locus_tag="RD508_003038"
     CDS             complement(10100..11023)
                     /locus_tag="RD508_003038"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HDT7737527.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            11219..11824
                     /locus_tag="RD508_003039"
     CDS             11219..11824
                     /locus_tag="RD508_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7737528.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12132..13148
                     /locus_tag="RD508_003040"
     CDS             12132..13148
                     /locus_tag="RD508_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDT7737529.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13289..14590
                     /locus_tag="RD508_003041"
     CDS             13289..14590
                     /locus_tag="RD508_003041"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDT7737530.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14636..15298
                     /gene="deoC"
                     /locus_tag="RD508_003042"
     CDS             14636..15298
                     /gene="deoC"
                     /locus_tag="RD508_003042"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDT7737531.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            15319..15717
                     /locus_tag="RD508_003043"
     CDS             15319..15717
                     /locus_tag="RD508_003043"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDT7737532.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15783..16865
                     /locus_tag="RD508_003044"
     CDS             15783..16865
                     /locus_tag="RD508_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7737533.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            17077..18639
                     /locus_tag="RD508_003045"
     CDS             17077..18639
                     /locus_tag="RD508_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7737534.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18632..19765
                     /locus_tag="RD508_003046"
     CDS             18632..19765
                     /locus_tag="RD508_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7737535.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19765..20721
                     /locus_tag="RD508_003047"
     CDS             19765..20721
                     /locus_tag="RD508_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7737536.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            20820..21986
                     /gene="deoB"
                     /locus_tag="RD508_003048"
     CDS             20820..21986
                     /gene="deoB"
                     /locus_tag="RD508_003048"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDT7737537.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            22010..22828
                     /locus_tag="RD508_003049"
     CDS             22010..22828
                     /locus_tag="RD508_003049"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDT7737538.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            22845..23552
                     /gene="deoD"
                     /locus_tag="RD508_003050"
     CDS             22845..23552
                     /gene="deoD"
                     /locus_tag="RD508_003050"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDT7737539.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT         7720 a         4202 c         4949 g         6857 t
ORIGIN      
        1 tggaactcga acaagaggaa agcataagat ttcagaattg ttctctgttc cctctttatc
       61 atggaagtgc aaaaagtaat atagggattg ataaccttat agaagttatt actaataaat
      121 tttattcatc aacacatcga ggtccgtctg aactttgcgg aaatgttttc aaaattgaat
      181 atacaaaaaa aagacaacgt cttgcatatt aagtagttca gttttggagt acaaaaagtg
      241 aaaatgtaaa cctaaatgag tatcaaattg caactgaatt tgatactcgt tttttattgt
      301 taaatcaacg tttgttgtta atttacacca caaaatgtaa gttaaaatgt atataaaaat
      361 gcgaacgtga aataattatt gtaggaatgc aaattggtgt gttaaaatgg ttacaattta
      421 ctaagcaaaa aggggtgcat tttcctatgc aatttcttga gccaaaaaat aagaacgcta
      481 agtctgtgga ttgggaaata tcagagcaag taagggtgat agttaagcaa tacgctgaat
      541 atgcagagcg tactgaaagc gaagcagtgg atgaattctt attgaacatt ttagacgata
      601 agaagtttat tgaatggatt gccaacaagc gaagtaataa gcggattgtt gaaaaaatgg
      661 gtatcaaaga tagagtgggt tgatagacaa tgaccaagct taaaagatta gccacgaagg
      721 aagatgaaat tgtagatgtt aaaattccga tttcaaacga agaattaaaa gatagggcta
      781 aacaatatga tttattaact ccaaaacgat ttgcaacaag gtataacaaa atgttgttct
      841 tgccaacgtc ttttaaatgg aacggttctg aatatcccat tcaatataat tactgcatca
      901 atccgttttg ttgtaatttt gggaaagaac agcacaaatt caaagatgta aaagggaaac
      961 caagtcgata taaaatgact ggtagttcca aagataaagg tcataaaggt atgtactgca
     1021 atgacaatcc tattggcaga ggtgtatcgc aaaactgtac agtaacccct ttatctaatt
     1081 ggtctgttgt tgaagaaatt aaacgcctta tagaaatcaa tagcatccaa gatgttgagc
     1141 cagattatca atttcataaa gaaggctgct cggaagaaga atcaacccca ttcaatgagc
     1201 cgaagcaatt ttacaaaagg gggaaaagta ggggcaaatc tcaacgctat caatgtaagg
     1261 cgtgtaagaa gttcactaat gttctaccaa aaagagaaga aaccactact tatcaccaac
     1321 aaaagaacac cattcttcca atgttcgcta agatggttgt tggaagggtt tcagtcagtc
     1381 gtacttgtga tattttagga attggagttg gaacctacta tcataagctg gagtggctgt
     1441 ataggcgttg tttggagttt ttagaacgat atgagacaca accccttcaa acaaagaaat
     1501 ttaacgagat gtggcttaat acggacaaga tgcactacta cctaaataac gtccgtaaga
     1561 aaggacaagg ttcaaagaaa tatacggggt ttgaagacct taatatgcaa acgtatatag
     1621 ttgtatctgc tgaggtctta tcaagatatg tgttccgttc tgatgttgcc tatgattgga
     1681 atatttcaat ggatgaatta aatgaagata caagaaaatt caaagaagac catctcaata
     1741 cttttagtcg taaaaatgat aggttagatt ggtcttatta tccacaagaa ccatccgcta
     1801 acgatagcga aaataggaat gcttatcttc acgaattagg gaaaattact aataggagta
     1861 gatttgtcga tggtttaaat gttgatgctc cttatactac aactgctcac tattggttaa
     1921 ttaaacaaat ggttaatgcc gacgaatggc gaatgattag tgatgatgac ttctctatta
     1981 gaaacgcctt ttatagagta ttcacgaaag aattaaggtt gagcgatgca catcatttta
     2041 tttgccaagt taacaagacg aaaagcagaa aacaatgctt aaaagaattc ggacaagcaa
     2101 aagcagaact gctcgattgg ggagatatca gaggattcaa aacaaagttt ctacggactt
     2161 tggcatctca ttatctaact gaattactaa caagtcatca attccacgaa gaggctatta
     2221 gtaaagatgg agaaagatat cgcaaatatg ccgataaccc tatcaaacat ccattagcca
     2281 ctaaggataa aggattttat tcagttgatt gtagaacgga tttatctgct ctggaaccaa
     2341 acgaaatcgc aaagatgcta ttaaatgtta atgaccattc gaccaatagc tttattcaac
     2401 agataagacg ttatatatca tctcttgaaa gaccattaac aacagctcgt ggtgataaga
     2461 agagctatat ttacgctaac ttcaatccga agtatgctca atttgcgatt acaattctaa
     2521 gaacttacta caacttttgt cgccctttta aatcagcgga taaaaaggtt ttgacacctg
     2581 ctcaaagatt agggattaca gataaacaat ttgattggaa agatataatt tatttcaaat
     2641 gacaaaaaga gcttggagta atcccaagct cttgtgcttt atctttactg ttcttcttca
     2701 attaacgcac ccgttaactc aataagtttt ttctttcata tacatgaaaa tagtagttat
     2761 acggattttt atcattcttt atcccttttt gggcaaatac ctcattccat tcctcataat
     2821 tcacttctgg aaaaaaagta tctccttcga attcatgatg tatttttgtg atgtacattt
     2881 tctcaacata agggaaaaac aaattataaa tctgttctcc tccgaaaata aaaatttctt
     2941 cttcgttttt acataactca aaaacatctt ctattgaatg aacaatttca caaccattaa
     3001 aggtaaaccc cttatctctc gtcagaataa tatttcttct gtcaggtaag gctcttccga
     3061 ttgattcaag gttcttccta cctaatatta tcggatgtcc ctttgtagta tttttaacat
     3121 attcccagtc cttgggaatc ctccaaggaa tgtcattctc tttgccaatc actctattct
     3181 tatccatcgc agcaatcaaa gaaactttca tttataacac agccttttta actaatttac
     3241 catctaattt cttatttcta tcaaaaaacc ttttctcatt atcctgcccg ttagttgaat
     3301 aagcaatttt ttctataagt tatattatca taataccaca aaatcacaaa ttttcattca
     3361 attatcattt tcaattgcat tttataaatc attttgtatg taatttggta tgtaagttaa
     3421 aatgaaaaaa gtagtccatt ttgaagtaca ttttgtcatt ttgtactcca aaactgaact
     3481 acttacttgc atatatacgc ctttatagtg gagtactaca tttacgagat tcggttagag
     3541 tatcagaaaa agaaaaaata aaagttacag aaatgtatac ttcaataaat ggtgaattat
     3601 gtaagattga tagagcttat tctggagaaa ttgttatttt gcaaaatgag tttttgaagt
     3661 taaatagtgt tcttggagat acaaaactat tgccacagag aaaaaagatt gaaaatccgc
     3721 accctctact acaaacaact gttgaaccga gtaaacctga acagagagaa atgttgcttg
     3781 atgccctttt ggaaatctca gatagtgatc cgcttctacg atattacgtg gattctacga
     3841 cacatgaaat tatactttct ttcttaggga aagtacaaat ggaagtgatt agtgcactgt
     3901 tgcaagaaaa gtatcatgtg gagatagaac taaaagagcc tacagtcatt tatatggaga
     3961 gaccgttaaa aaatgcagaa tataccattc acatcgaagt gccgccaaat cctttctggg
     4021 cttccattgg tttatctgta tcaccgcttc cgttgggaag tggaatgcag tatgagagct
     4081 cggtttctct tggatactta aatcaatcat ttcaaaatgc agttatggaa gggatacgct
     4141 atggttgcga acaaggatta tatggttgga atgtgacgga ttgtaaaatc tgttttaagt
     4201 acggtttata ctatagccct gttagtactc cagcagattt tcggatgctt actcctattg
     4261 tactggagca agcctttaga aaagctggaa cagaattgtt agagccatat cttagtttta
     4321 aagtttatgc accacaggaa tatctttcac gggcatataa cgatgctccc aaatattgtg
     4381 caaatatcgt aaatactcaa ctgaaaaata atgaggtcat tattattgga gaaattcctg
     4441 ctcgatgtat tcaagattat cgcaatgatt taactttttt tacaaatggg cttagtgttt
     4501 gtttagcaga gctaaaagga tatcaggtta ccactggcga acctgtttgc cagacccgtc
     4561 gtctaaatag tcggatagat aaagtaagat atatgttcaa taaaataact tagtgcgttt
     4621 tatgttgtta tataaatatg gtttcttatt aaataagatg aaatattctt taatatagat
     4681 ttgaattaaa gtggaaagga ggagattgtt attataaact acaagtggat attgtgtcct
     4741 atttgtggaa ataaaacaag actacgaata cgagtggata ctatacttaa aaatttccct
     4801 ttatactgcc ccaaatgtaa gaacgaaact ttaattaatg ttcaaaaaat gaatataata
     4861 acaatcaaag agccagacgc caagacgcag agccgataat ttgagaaatg aaactctcat
     4921 cttatcggct ctttttgttt atctgaattt tactgactag ccttcaatat ttcttgcttc
     4981 attgatacct tttgctagtg cttccattaa ggatagttct ttgtctgtaa agctatccat
     5041 gtatttttct acctgtaacc ttcgagtgct tttaatcaaa ttatctgtag gtaagaaaaa
     5101 ttcatcaata gatacatgga gtaatgatac aagatcatac agcacttgtg tacttgggtg
     5161 ttgtcctttg ttttctatat ttgttaaata acgtgggtca atttcaatca ttgttcccac
     5221 ttgttcacga gtgagacccc gtttcattcg agcctcttta atcgctaaac caacggctct
     5281 aaaatcgtat ttatcttctt ttttacgcat actaaatcac ctctatacat tttactgttc
     5341 ctatataacc ataaacaggt atagaaaaac atgttatata gtttatgagt tcctatagaa
     5401 cactgtggaa tttattaatg cgatgaatcc aatttcaaat agaaaggtcg ctgattttat
     5461 ttacctatac aactttataa aatttagtca tactcctaga aagtagataa aattggcgac
     5521 ttaatggagg gaaaagtcgc catgagaaag ataatctgtc atctagttct cttaattaag
     5581 ttcttatcaa aaaaacttat ccacctgtac tggatagata tgaccatcaa tgtggttttg
     5641 cagattacat agatagaaaa atcaaagcat atgaacagag aaaacaatct gtttatgtgc
     5701 ttttttggtc acttaataaa tatcttttag gatttctctt catttatgca acaaatcccc
     5761 cgttcgtgtc ggggtttagt atgaagggag ataaagaagc acatgccact ccctttcacg
     5821 acagaaaggg ggtgaaaagc atgaaaccat cttcttttca agaaaccata gaaaatcagt
     5881 ttgactatat ctgcaaacaa gttattgaag atgaacgaaa agattacttc aaacatctag
     5941 acagactatc agcaaaagaa gtctcgtttt ctgatataga taactacctt gtcaactctt
     6001 tttctactgt tgatacgtac gtcactgatt tccaactatt taaattattt ggattaagaa
     6061 tcaatgttga aagtgattta ttaagtgaag ccctgcgtca tctttcagag aaaaaacgga
     6121 acattatttt acttcattac tttatggata tgagtgatgt ggagattgcg gagttactaa
     6181 atttgaatcg ttcgactgtt tatcgtcatc gaataagtgg actagccatg attaaagaat
     6241 tcatgaagga gtgtaaagaa tgaaaacagc ttatccaagg gttcccttcc ccctcattgt
     6301 aaaggcgaca gatggcgacg tggaagcaat taatcagatt gttaaacatt atcgagggta
     6361 tacctcaaaa cgttcattac gtcgcatgac agacgaatat ggaaattctc atatggttat
     6421 tgatgaaacc ctacgtggca gaatggaaac gaaactcatc tctaagattt tatcgttcga
     6481 aattaaatag tcccattttt tcgtggaagc gtgtcgaatc gtatccacgc ttcccgattt
     6541 gggaggtttg ttattccatc aaagcatatt gtgtgttcag taggttttga taggctaaca
     6601 agccaaacgt tctttgacaa ccaaataaag gcaatcgaat acgtttcggt aagaaaagag
     6661 ctgatgaact aacacgccat gacctacaaa attagtgagc gattcatgtt agtaattcga
     6721 aagtaatctt tagcaggatt gctgccatga ctttcttatc gtgataatga tactcccgta
     6781 tagccatagt ccgagcgtta gaagcgtcac aggcaatggg tacggctaca tgagaaccat
     6841 gcagaagtga aattcctgtg agctttgcta gagctgttcg attgctaaga tattcttctc
     6901 ttgtcagtgt attattataa aactatttga tataattata ggtgaatatt ggagttttcc
     6961 tagcctataa ttgggaaagg agtaataatg ataacggtca caaaaaagga tttagttgag
     7021 ctaggatatg gaacttcttt ttcagcagac atcataaaaa aagcaaaaga attgatgatt
     7081 acaaaagggc atatctacta tcaatctcga aagctagata gagtccctcg tgaagctgtt
     7141 gaagaaattc taggaattcg gttttcaaat gaaaacaggt ctgagtagtt tttgcacagt
     7201 aaggagtaaa aactatggtt aaagacccaa taaaaaaagc aaagaatgga acctattatt
     7261 ttcgtgcaaa tctaggttat gattctaaag ggaaaaaaat tcaaaaatat cgtagtggat
     7321 tcactactaa aaaagaagca agagaagaat attcgaaact gctattgatg aaaccagaag
     7381 aattaagtga gaataaggat aaaatgacgt ttaaacatta tatctttgaa attttccttc
     7441 catggtataa gacacaggta aagctcagaa catatgaaaa tcgcttacca actattaaga
     7501 agcatttctc ttattttgat aaaatggctg tttccgatat tgagcctatt gatgtgcaaa
     7561 attggcaact aaaattatca aagaagtgta agtcttctta tgtaagagct gttcaaggac
     7621 tattttcagt tgctatggat cgagcaattg tccttgggat aaccaccaca aatccatcta
     7681 agattattgg caatgtgaaa aagcaaaagt ctaaaattga attttggaca aaagaagaat
     7741 ttgaaaaagt aatctctcta atttacaaag aagattacta tcaacacttt ttatttatct
     7801 ctctgtggtt tttatttatg actggaatgc gaattggtga agctactgcc attcaatggg
     7861 aagatattga ttttgactca ggagtactaa ccatcaacaa aacactctat tacaagaatc
     7921 aatcgaatta tagatttgtt gaaccaaaaa caaaggcgag cgttcgtcat attgtattag
     7981 ataaatgcac attaacttat ttatccgaat ggaaggaagt acaacaaaat ctaattcaga
     8041 cagactttgt aatgagctat aacggtattc ctacccaaaa acatacacta tcatatgcta
     8101 ttgaacgcta tgctaagctg gctggtatcc atcgaatcag aatccatggg ttacggcatt
     8161 ctcatgcttc cttgttaatc agtatgggag aaaatccact tatcattaaa gatcgtctag
     8221 gacacgaaga tattgagacg actttaggaa cgtatggaca tctttatcct aacagtaatt
     8281 tcgaggtagc taacaaatta aatggagcca tttcctttaa agaagcaaaa caaaattatg
     8341 atacttcacc aaagaatcaa tttactgtag actacttgcg aaacaaagaa atgaaaaaag
     8401 tgcaataaaa gtgcagtaaa aagataagaa gagccagaaa cccttggtat aagaggattt
     8461 ctagctctcc tacaactatt cccactccac tgttgctggt ggtttagaag tgatgtcata
     8521 cacgatacgg ttgacgtggg ctacttcgtt tacgatacgt acagagattt tttgcaagac
     8581 ttcccatggg atacgggcaa agtcagcggt cattccgtcg attgaagtta cagcacggat
     8641 accgactgtg tagtcgtaag tacgtccgtc acccataaca ccgacagagc ggatccctgg
     8701 aagaacagtg aaatattgcc agatatcacg gtcaagtcca gcagctgcga tttcttcacg
     8761 caagatagca tcagattcgc gtacgatttc tagcttgtct tcagtgattt cgccaagaac
     8821 acgaatacca agaccaggac cagggaatgg ctgacgccaa acgattgaat caggcatgcc
     8881 taactgagtc cctaattcac ggacttcgtc tttgaataat gtgtttaatg gttcgatcaa
     8941 ttcaaattgc atatcttctg gcagtccacc tacattatgg tgagatttga tcgtctgtgc
     9001 tgtttctgta ccagattcga taacgtcagt atacaacgtt ccttgtgcta ggaaagagac
     9061 gccttcttca ccagcaagtt ttgttgcttc gtcatcaaaa acatatacga attcattccc
     9121 aatgatttta cgtttttgtt ctgggtcaga tacacctttc aacttgtcta agaagcgatc
     9181 tcttgcatcg actttgatga tgttcaagcc gaattttccg cctagacttt ccattacttg
     9241 ttccgcttcg cctttgcgta gcagaccgtg gtcaacaaag atagatgtca attggtcacc
     9301 gatcgctttt tgtaaaagaa ccccaacgac actagaatca acgccacctg aaagaccaag
     9361 caagactttt ttgtcaccaa cttgttcacg gattttttct acttgcatat cgataaagtt
     9421 atccattgtc cagttacctt cacagtgaca aacatcaaag gcaaagtggc gcagcaattc
     9481 gattccgtat tcggaatgac gtacttctgc atggaattgg ataccataaa aattacgtgt
     9541 tgtgtcttgg atagaagcaa tcggacaatc tttgcttgtt ccgactgttt caaagccttc
     9601 aggaacttta gttaccaagt caccatggct catccatact gtttgttgtt ttggtgtttc
     9661 tttaaacaag acagcttgat cgcttgttac ttctaacaag gctttcccat attcgcggtt
     9721 tttagcaggc tctacggaac cgccaagttt gtacgtgatc aattgcatac catagcaaat
     9781 ccctaataca ggaataccta aattgaagat ctcaggatcg atcccaaatg cattctcatc
     9841 atatacactg tttggtccgc cagaaagaat gattcccttt ggattcatcg cttttacttc
     9901 ttctgcagta atgcggtggc tcaataattc ggaaaagact ccaagatcac gaatacgtct
     9961 tgtgatcaat tggttatact gactaccgta gtctaatacg ataatctttt caacgttcgt
    10021 catatcggca acgtttgtca aatttattac ccctatccct ttaaatttta tctcaaaata
    10081 gtcaaactat tttaaaatgc taatattttc gcatgaaaat cgaatcgatg atatgatttt
    10141 cagttttatg gagaattata tcggctcttc ctcgtgtagg caagatatat tcctgtaaat
    10201 ttttcaaatt cacatttttc catacatctt ttgccatttt aaaggcttct tcacgatctc
    10261 cgatagcaaa acgataataa taattctctg gattttggaa agccgtatcc agtaacgcac
    10321 caaaacgatc caaataccat ttttcgatca gcacgggatc ggcatcgaca tagacagaaa
    10381 aatcaaaaaa gtcgctgacg tagatttgct gattcgcagg taattgaagc gtattgatcc
    10441 cctcaacgat caagatatca ggctgctgga tcaattcgta cttgtctgga atgatatcat
    10501 acacatcatg tgagtaaaca ggtactttta tctcttcctg accagatttt acacggttca
    10561 agaaatcgat cagcatctcc atatcataac tttcaggaaa tcctttacgg tccatgattc
    10621 cacgctcttt taatatacga tttggataaa gaaatccgtc agtcgtgatc agctgaacgt
    10681 ttcttcgttt gaaggtacga gacaaaatcg tctgcagcag tctggctgtt gtactttttc
    10741 caacggctac acttccggcg atcccgataa taaaaggcgg tacttctacg tatttatgaa
    10801 gaaataaacc tttactcaag aacaaagatt caaattcttt catataaaga taaatcagat
    10861 gagcaagagg tacatagata tctcgaacat cctgcatgga aatgcggtca ttcaaacttt
    10921 tgatattatc tagttcatct tgtgtcaaag gtgcttgccc attacgataa aattctcgcc
    10981 attcttctct tgccacacgg tagtagttca ttggatcatt catattagcc tcctgcgttc
    11041 tcccatcaat ggaactattt taacacaaaa taaacgcaaa ccccaccact taagagagat
    11101 tgccgatctt tttgtataat ctttataata gaaagaaacg gagtcttatt cttgacttgc
    11161 gcacggatac ataaaaggat agactgttgt catgaaagaa atgagaagga tggaagacat
    11221 gacaaatcat tactattctg aacgcccaga tacggcgcac gattttgaac aatgggcttt
    11281 tgagttaaaa ggcagaacct ttcaatttgt aacagattct ggtgtatttt cacgtgaaac
    11341 agtggattat ggttcacgtg tcctgattga tgctttcgat tgggaagagt tacctgatga
    11401 aggaaagatc ttagatgtgg gatgcgggta tggaccgatt gggttagctt tggcatttgc
    11461 gacacagcgg tttgttgaaa tggtcgacat taatgaacga gcggtaagtc tagcgcaagg
    11521 aaacgcaaag cgtaaccaaa tcgaacatgt tgatatccat caatcgaata tctatgaagc
    11581 agttcatgaa gaaacctatg cagctatcgt aagcaatccg ccgatccgtg ctggaaaaaa
    11641 agttgtacat gaaattttga caggcgcata tcctcggttg aagaagggcg gtacactgac
    11701 aattgtgatc cagaagaaac aaggagcgcc gagtgcgcaa aagaaaatgg aagaaacatt
    11761 tggtaatgca gaaatcgtca caaaagataa aggatattat atcatcaaaa gtgtgaaaga
    11821 ataactagct gaaaaatagt ggagcgacga aagagtggaa ctgggcgtgc atgtacgggt
    11881 acgtatcagt tctttttttg ttgagaagtt tttaaaaaca aagaactatt ttttcttcaa
    11941 aaagaaatag taggaacaga gtcgttgttt tttacgataa aataaataag atacagaact
    12001 tgtatagaag gctgccaagt cggtagataa aggaggtttt tatcaaaaaa catactttcc
    12061 ttttttctct attcttttct tgggggtttt ggtacactga tagggaattt agatagaagg
    12121 gagccaatag gatgaagctg accatcagag atatcgcaga aatggcaggc gtatcagtaa
    12181 caactgtctc acagattttg aataacaaag gaagcagatt tagtgataag acaagaaaaa
    12241 aagtgttgtc gatcgtgaat gaacatcatt ataagcccga ttatttcgct tcaaatgtga
    12301 tcaatcgaca ttcaaagacc atcggaatga tcgtccctga tgtcactgat ttcttcttct
    12361 ccaaactgat cgaaggtgta gagagctatt tgaatccttt gggctatgtg atcatgttat
    12421 gcaattctcg tcatagccaa gaaaatgaga tcaagtattt acaagagctt tcccaccgct
    12481 cagtggacgg aatcttgctg gccacaccaa atattttacc tgagaaatat gcattagaca
    12541 gcggttttta tcaaaaaatg ccaatcattt taatcgatcg cggattgaat cgtcgggata
    12601 acggacggct tatcgtaaag gaatatgagg gcgcctatca agctgtttcg ctgtttattg
    12661 aaaatggcca tacgaagatc ggcatgctga aggaaaccac tggatactat caattagaag
    12721 aacgtttcaa cggatatcgt catgcgctga aagatcatgg cctgcctttt aatgggaaat
    12781 ttgttgaaca tggagagttg actgtccaag gtggatatac tgcatcaaaa aaattactca
    12841 aacataaaga tatcacggct attttttgcg ggaatgatgc catggcgatc ggatgctatc
    12901 aggcgatcga tgaattgggc aaaaaaatcc cagaagatat ctcagtcata ggattcgatg
    12961 gattaaagct gtcagaatac atgattccgc aattgacgac agtgcagcag ccaagttttg
    13021 atattggatt ttatgctgca cgtttcctga tcgatacgat cgaatttcct caaagaaaag
    13081 ttccgaacaa agtgttcgaa acaaaattaa ttattcgtga gagcgtaaaa gtattgacaa
    13141 agggctaact cggcggtata ttgcttatgt aagcatttac aaaggctagt tagtgctttt
    13201 tttattttta gtaaaccagt ttactaaagt ggtttacctt tcctaaaaat aatgtataat
    13261 accgaatgaa gacaaggagg atcaggcaat gcgaatggtg gatctgattg aaaaaaagag
    13321 ggatggaaac gagctgtcga aagaggaaat cgagtacatc gtcacgaact atacgaatgg
    13381 aaagattcca gattatcaag tcagtgcatt attgatggca attttttatc aagacatgac
    13441 aaatgaagaa atcacgaact taacattggc gattgctaat tctggtgatg tcatcgattt
    13501 gagttctctt gaaggaataa aggtagataa gcattcgaca ggtggcgttg gtgacacgac
    13561 cacattgatt ttagcccccc tagtagctag tgtcggagtg acagtggcta aaatgtctgg
    13621 acgcggtcta ggttacacag gtggtacact agacaagcta gaagcaattc ccggatttca
    13681 gatcgagctt tcggatgaag aatttgtacg cattgttaat gaaagtaaag tagcggtaat
    13741 tggtcaatca ggaaacttgg caccggcgga caaaaaattg tatgccttgc gtgacgtcac
    13801 agcgaccgtt gattctcttc cgctgattgc cagttcgatt atgagtaaaa aaatcgcggc
    13861 aggagcagat gcaatcgttt tggatgtgac cactggagac ggtgctttca tgaagaacat
    13921 cgaagatgca agacgtctgg caaagaccat gacgagcatt gggaaactgg ctaaccgaga
    13981 aacagtggcg gttatctcag atatgtcaga acctcttggc gaagctatcg gaaatagtct
    14041 agaagttgtc gaggcaatcg aaacattaca aggaaatggt ccagaagatc tagtagaaat
    14101 gtgctacgcc ttaggaagcc aaatggttgt tcttgctggc aaagctaaga caaccgatga
    14161 agcaagaacg ttgcttcaag aagctctgga atcaggtaaa gcgttagcaa aattcaaaga
    14221 aatgatccaa aatcaagggg gagacccagc gatcgtggaa catccagaac gaattttgac
    14281 tgcacgctac acaatggagc ttcctgctaa acaaagcgga gttgtgtcaa aaatcgtggc
    14341 aaatgaatta ggaattgctg caatgatgct aggtgctggg cgtaaaacca aagaagaaga
    14401 tattgatcac gctgttggat tgaaactgca taaaaaaatt ggtgacactg tgacaaaagg
    14461 tgagtcacta ttgacgatct atagtaacga cgaagaaatc acttctgtca ttgaattatt
    14521 atataaaaat attgaaattg gtgaatcggc aatgaagcca acgttgattc atgacatcat
    14581 cacagaataa aggaaaaaag cggactttac cgttttaaag aaaaggggaa aagaaatgga
    14641 actaaaccga atgatcgacc atactatttt gaaagcagac gcatctaaag aagctgtgat
    14701 gcaaattatc gaagaagcaa aaaaatacca tttttattct gtctgcatca atccagcatg
    14761 ggttgcgcta gcgaaagaac aattacaagg tgagccagta gccgtatgta cagtaatcgg
    14821 gtttcctcta ggagcaaaca cacccgagac aaaagcattt gaaacaacag atgccatcaa
    14881 taacggtgca gatgaagtcg atatggtcat caatatcggt gctttgaaat caaaggatga
    14941 tcaacaagtc caaaaagata tcgaagcagt tgttgaagca gcaaaagatc gtgcgcttgt
    15001 caaagttatt attgaaacat cgttattaga tagagaagaa atcatccgag cttgcgaaat
    15061 agcaaaagct gcaggcgctg attttgtcaa aacatcaact ggtttctcaa caggcggagc
    15121 aaaggtagag gatgtccgtt tgatgcgtga aactgtagga ccagaaatgg gtgtcaaagc
    15181 ttccggcggt atccataacg aagaagaagc aatggcaatg atcgaagctg gtgctacaag
    15241 aatcggaaca agcgcaggag tagcaatcgt atctggttca actggtgaag gctattaatt
    15301 ttttcaaagg agaagctcat ggcagaactc aaacaagaat ggatcaacac agctattgaa
    15361 gcgttagata aagcctatgt tccttattcc cattttccgg taggcgcttg tctcgtaacg
    15421 gaatcaggca agatttatca aggcatcaac attgagaatg catcatttgg attaacgaat
    15481 tgtgccgagc gcacagcttt tttcaaagca gtatctgaag gagaaaaaac atttacgcat
    15541 ctagtcgtag cggggcacac ccccgatcct atctctcctt gtggtgcatg tcgacaagta
    15601 atggcagaat tctgttcccc tgatatgccg gttacgctag taggagacaa tggtgtgacg
    15661 aaggcaacga ccgttcgtgc actgctgcct tatgcattta ctgaaaaaga tctataactc
    15721 atgttcattc agtcagctga ctgttgaaaa ataaaacaat tattttagga ggctttacag
    15781 aaatgaaaaa agcaaaatta tttggtttag gtgctgtcgc actagcagca gggttatttt
    15841 taggtgcatg cggcaacaac ggctctactg attcatccgg tggcaaaagc tcatcagaca
    15901 caacaactgc agcattgatc acagacacag gtggtgtaga cgaccgttca ttcaaccagt
    15961 cagcttggga aggactagaa aaatggggga aagatcaagg actttcacga ggaaatgatg
    16021 gcttccaata tttccaatct tcaaatgaat cagattacat cccaaatatt gaccaagcat
    16081 tgaatgctgg attcaaaacg atttttggta ttggttataa actaaaacca gcgatccaag
    16141 aacaagcaac aaacaataca ggtacgaact ttgttattat cgatgatgtc atcgatggat
    16201 tagataacgt tgtatctgca actttcaaag acaacgaagc ttcttatctt gcaggtgttg
    16261 cagcagctta tacgactgaa acaaacgtag tcggctttat cggcggtgta aaaggtgaag
    16321 taatcgatcg ttttgatgct ggattcaaag ccggtgttga tgcaggtgcg aaagaattag
    16381 gaaaagaaat caaagtattg aatcaatatg ctggtgactt ctctgctcca gataaaggac
    16441 gttcaattgc tcaaggtatg tatgcacaaa acgcagatat catcttccat gcttcaggcg
    16501 gtacaggtaa cggtgtattc caagaagcaa aatcattgaa cgaatcaggc gacaaaaaag
    16561 tttgggttat cggtgttgac cgcgaccaat cagacgaagg cgaatacaca ttaaacggcg
    16621 aaaagaaaaa cttcacattg acatctacac tgaaagcagt tggaacagta gtagaagatt
    16681 tggcacaaaa atcagcggac ggtaaattcc ctggcggcga acacactgtt tatggattga
    16741 aagaagacgg tgttggtcta acagaaggac aactttctga cgaagcgaaa aaagcagttg
    16801 atgaagcaaa agaaaaaatc atttcaggtg acgtaaaagt tccagaaact cctgaagaaa
    16861 actaaaacca tttctatagc cttgttagac acatgtttga caaggctatg gtttgattag
    16921 aacaagaatt gttcatttat ccaagctgcc ttgtgacagt ttggataagg gaacaactcc
    16981 ctgaagtaat gtttgtttca aaagaagaac gctcactaag cgtgaatctt agtcaatcgt
    17041 tgccctagat agaaatcgtt aggatgtgaa aaaaaggtgg ttcaagaaaa tattgtcata
    17101 gaaatgcaga atattaccaa agaatttgga acattcaagg caaatgacaa catcaattta
    17161 caagtaaagg caggagaaat tcatgcgttg cttggagaaa acggtgctgg caaatctaca
    17221 ttgatgaacg tgctttccgg attattagag ccgacatcag ggaaaatttt gatgcgtggg
    17281 aaagaagtaa agatcacaag tccgaccaaa gccaaccaat tagggattgg gatggtccat
    17341 cagcacttta tgcttgttga tgcctttact gtaacagaaa acatcgtgtt gggaagcgag
    17401 cctagtcgcg cagggatgct tgaccataaa aaagcacgaa aagagatcca aaaagtttct
    17461 gaacagtatg gattgtcagt caacccagat gcttacgttc gtgatatttc agttggaatg
    17521 gaacaacggg tagaaatttt aaaaacactt taccgaggag cagatgtact gatttttgat
    17581 gagccgacag ctgtattgac ccctcaagaa attgatgaat taatcgtgat catgaaggaa
    17641 ttagtcaaag aaggcaagtc gatcattttg attacgcata agttagatga aatcaaagca
    17701 gtagctgacc gctgtacagt tatccgccgt ggaaaaggaa tcggtacagt caacgttaaa
    17761 gacgtaacct cacaacaatt agccgatatg atggttggaa gaacggtttc attcaaaacg
    17821 atgaaaaaag aagcgaagcc tcaagaagtc gttttgtcta ttgaaaatct agtggtgaaa
    17881 gaaaatcgtg gattagaagc cgtgaaaaac ttgaacttag aggttcgtgc tggcgaagta
    17941 cttggtatcg ctggaatcga tggaaacggg cagtcggagt tgatccaagc tttgactggt
    18001 ttgcgaaagg cagaaagcgg acatatcaag ctaaaagggg aagacatcac taataaaaaa
    18061 ccccgaaaaa tcactgaaca tggtgtagga cacgtgccag aagaccgtca taaatacggg
    18121 ttagtcctag atatgacatt atctgaaaat atcgcactac aaacctatca tcaaaaacct
    18181 tacagtaaaa acggcatgct gaattattca gtaatgaatg aacatgccag agaattgatc
    18241 gaagaatatg atgttcgaac aacgaatgaa cttgttcccg caaaagcttt atcaggcgga
    18301 aatcagcaaa aagcaattat cgctcgtgaa gtcgaccgag atcctgatct gttgattgtt
    18361 gcaaatccaa ctcgtggact ggatgtaggt gcgatcgaat ttattcataa acgtctgatc
    18421 gaacaaaggg acaaatacaa agcagtgtta ctgatcagtt tcgaattaga agaaatttta
    18481 aatgtttcgg atcgtattgc tgttatccat gaaggagaaa ttgtcggtat cgttgatccg
    18541 aaagaaacat ctgaaaatga attaggtcta ttgatggcgg gctatacctt agaagaagca
    18601 cgaaaagagt tagaaaaggg ggctggcgca catgaatgat cgcagcgaaa aattccgtaa
    18661 tttattagtg cctgtacttt cagttgtttt aggattgatc ttaggcgcga tattgatggc
    18721 tgcttttggt tttcagccca tccaaggtta ttcttctatg ctagatgcag cccttggttc
    18781 gcaaagaggg ataggtgaaa cgttaaggca agcaacgccg ttgattttta cagcattagg
    18841 tttttctgta gctaactcag ctgggttttt caatattggg ctttctggac aagcactttg
    18901 cgggtggatc gtcagtgtct gggtggcact tgcgtttcca gatctgccaa aagttgtttt
    18961 gcttccgtta tgcgtgatct taggtgcctt agctggtgcg atggcagcgg ctgttccagg
    19021 tttacttcga gcattttttg gaacaagtga agtgatcgta acaatcatga tgaactatat
    19081 cttattatac gtaagcacat ttgctttaca tgaagtgatg cctgaaagct atcgctcaag
    19141 tttggactct tccaatatga tcagtcaaaa tgcctcactg cggttaccat ggttaacaca
    19201 agcttttggc ggctctcgcg taaactcagg attattttta gcaatcatcg cgcttatttt
    19261 cgtttggctg ctgatgaaga aaacgacttt aggatttgaa atccgttctg ttggattgaa
    19321 tccttttgct tctgagtatg caggaatgag tagtaaacgt acgatcgttt tgtcgatggt
    19381 catttctggc gctttggcag ggcttggcgg tgtggttgaa ggattaggaa cgtatcaaaa
    19441 cttctttgtt caaacgactt cgctatctat tggatttgac ggaatggctg tttccttgct
    19501 tggttctgga tcagcaatcg gtattctttt atcagcgatc ttgttcagta ttttgaagat
    19561 cggtggactt ggcatgcaga caggagcagg tgttccgttt gagatcgtca atgtatcgat
    19621 tgctttgatt atcttctttg tcgggatcaa cttcctgatt cgtttcgtca tggctaaagt
    19681 cttccaaggg aaaaaacaag aagagatcgt tgcgacaata gaatcgaaac caacgaatca
    19741 aaaccatgaa gggggcgaac tataatgtcg actatcgaat taattgcctt gatccttact
    19801 tctacactgg tttattcaac accgctaatt ctaacgtcac taggcggaac tttttctgaa
    19861 cgaagcggga tcgtaaacgt agggctagag ggaatcatgg tcatgggtgc ttttagttcc
    19921 atcgttttca acttgacgat gagtccatca cttggttcta tgacaccatg gatcgctatt
    19981 ttagtgggtg gcgtcgtagg tatcctattt tctctgattc acgcagtagc aacagtcagt
    20041 ttgcgtgctg accatattat cagcgggaca gtaattaatc tgatggcacc tgctttaggt
    20101 gttttcttga tcaaagcatg gtatggtaaa ggtcaaactg ataacatcac gcagaatctg
    20161 gggtattttt ctttcccagg attagcagat attccggtca ttggaccaat tttctttaaa
    20221 aatacattct tacctgctta ttgtgctatt ttgattgctg tcctagcttg ggtgatcatc
    20281 ttcaagacga aattcggctt gcgcctccgt tcagttggtg aaaatcctca agctgccgac
    20341 acattaggta tcaatgtata tgctatgcgt tattcaggcg tactgatttc tggcttgtta
    20401 ggcggtatgg gcggtgctgt ttttgctcag tcgatttccg gtaacttttc agctggtacg
    20461 atcgttggac aagggttcat ctccatggct gctatgatct ttggtaagtg gaatccttta
    20521 ggggcaatgg gtgcctcatt gttctttggt tttgctcaaa gcttgagtat cattggcgca
    20581 caattaccag ttatttcttc gattccgcca gtattgctgc aaattgctcc atatttgctg
    20641 acaatcattg tgctggttgt tttcttaggg aaagcttctg gtccaaaagc aaacgggaag
    20701 aactatatca aatcaaaata atcttttagc gaataaaaag ggtgggttac gggaagtgtt
    20761 tttcgtctcg ccctttttgt tttaaaggca ataaaaataa aaagaaagaa ggaataatca
    20821 tgtttaaacg cgtacatctg atcgtcatgg attcagtagg aattggagaa gcaccagatg
    20881 ccgataagtt cggtgatgtt ggttctgata cattaggaca cattgcgaaa gaagcaggat
    20941 tgaacgttcc acatttagag cagcttggtt taggaacgat ccgtcctctt gaaggtgtgg
    21001 aatcagtgaa agatcatcaa ggctatgcga cgaaattaga agaagtttct gtagggaaag
    21061 atacgatgac aggccactgg gaaatcatgg gattgaatat caaaactcca tttcgtgtgt
    21121 ttcctaatgg attccctgat gatctgatca aacaaatcga agaattttct ggccgtaaag
    21181 tcgtatgtaa caaaccttat agcggaacag ctgttattga cgattacggt gaacaccaaa
    21241 tgaaaacagg cgatttaatt gtatatactt ctgccgatcc tgtccttcag atcgcggcac
    21301 atgaagaaat cattccttta gaagaattat atcggatttg ccaattcgtt cgtgatataa
    21361 caaaagatga tccgtatatg attggccgaa tcattgcacg tccgtacgtg ggtgaaccag
    21421 gagacttcac acgaacaagc aatcgccatg attatgcgtt gaatccattc ggacacacag
    21481 tccttgattc tttgaaagaa gcaggaaagg acgtgattgc tgttggaaag atcaacgata
    21541 ttttcaacgg acaaggaatc actgaatctg tccgcacgaa aagcaatatg gatggcgttg
    21601 accagctgct gaaagttatg aaaaacgatt tttcaggaat cagctttacc aatttagtag
    21661 attttgatgc attatacggt catcgtcggg atgtagtcgg ctatgcgcat gcgattgaag
    21721 aatttgactt acgaattcca gaattgcttg aagcgatgga agaagacgac ttgctaatga
    21781 ttacagccga tcacggaaac gatccgacgt ttactggtac cgatcatacg cgagaatatg
    21841 taccgttatt ggtttacagt aaaaaaatga aagaacaagg ggcattgcct caaggatatt
    21901 attcagatat ttcagcaacg attgctgaga actttagtgt ttcttcgact gaaaatggcg
    21961 aaagcttctt gaaattatta aaataatctt tttaaatagg agaaagcaaa tgaccaagtt
    22021 aagcgagatg ttacaagaaa cgacccagtt tatccttgat aaaggagtaa aagaaattga
    22081 ttttggtttg attctaggtt caggattagg tgaattagca gatgaaatcg aagatgctgt
    22141 aatgatttct tatgatgaga tcccgttctt tcctgtttcg acagtagttg ggcatgcagg
    22201 aaagctagtt tatgggtctc tggcaggcaa gaaagtgtta gccatgcaag ggagattcca
    22261 ctactatgaa ggtcattcca tgcaaacagt gacctatcca gtacgtgtga tggccggact
    22321 aggggcccat tcagtcattg tgactaatgc atgtggtggt gtcaacgaat catttgtacc
    22381 aggagatttg atgctgatta ccgatcatat caattttact ggtgaaaatc ctttgatcgg
    22441 tccgaatgaa gatgcaatgg gccctagatt tccagatatg agtcaagctt atacgcctga
    22501 ctatcaagca acagcaaaag cagcagcaga aaaactaggt ttggatctta aagaaggcgt
    22561 atatatgggc tattctggac caacttatga aacgcctgcg gagatccgaa tgtctcggac
    22621 aataggagcc gatgcagtag ggatgtcgac tgttccagaa gtcatcgtag cagctcacag
    22681 cggattaaaa gtgttaggaa tctcttgtat taccaactta gcagcaggta tgcaagcgaa
    22741 tctgagccat gaagaagttg tagaaacaac tcagagagtc aaacaatctt ttaaagcatt
    22801 ggttaaagaa acattgacat tattgtaata ggaggaacaa taaaatgagt gtgcatattg
    22861 aagcgaaaga aggcgagatc gccgataaga ttttacttcc gggagatcct ttgcgagcta
    22921 aatatattgc ggagactttt ttggaagatc cagtttgtta caatcaggta cgcggtatgt
    22981 taggctttac cggcaaatat aaaggagaac gtatttctgt tcaaggaaca ggaatgggaa
    23041 tgccatcagc caccatctat gcccatgaat tgatccagtc gtatggtgta aagaaattga
    23101 ttcgagtagg tacatgcggt gcattgtcaa aagacgtcca tgttcgtgat ttagtactag
    23161 cacaaggtgc agcgaccagt tcttcgatga tcgaaaaaaa tttccaagcc tttcattttc
    23221 ctccaatcag tgatttcaat ctattactga aagcatatga gatagctaaa gaaaagggct
    23281 atacggttca tgtaggaaat gttctttcgg aagattcttt ctacaaagat gatttgacag
    23341 agacgttcca attagctgaa cttggcgttt taggagtgga aatggaagca gcggctcttt
    23401 attacttagg cgcgaaatac catgtgcaga cattaagttt gatgaccgtt agcgaccatt
    23461 tgatcaccgg tgaagaaaca acagctgcag aacgtcaatc tacgttcaat gaaatgatcg
    23521 aagtaggatt ggaaacagcg atagcagaat aagaaggaaa tgaaaaagct gccctgcatt
    23581 aagtaataag aacatccaag caaaaatagc tcctcatgtt tttgacttgg ctggacttat
    23641 tattgcaaat gtaagctttt gaacaccgtt taccaagagg ttgtgaatct gccgtttaac
    23701 tctgagtcac aaggaacaat ttcaaaaa
//
LOCUS       DAPBCF010000200        13246 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.guided.066, whole genome shotgun sequence.
ACCESSION   DAPBCF010000200 DAPBCF010000000
VERSION     DAPBCF010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.guided.066"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(204..2162)
                     /locus_tag="RD508_003051"
     CDS             complement(204..2162)
                     /locus_tag="RD508_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7737540.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="RD508_003052"
     CDS             complement(2159..3031)
                     /locus_tag="RD508_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7737541.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="RD508_003053"
     CDS             complement(3373..4245)
                     /locus_tag="RD508_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7737542.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="RD508_003054"
     CDS             4373..4942
                     /locus_tag="RD508_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDT7737543.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="RD508_003055"
     CDS             5009..5746
                     /locus_tag="RD508_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7737544.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="RD508_003056"
     CDS             5977..7245
                     /locus_tag="RD508_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HDT7737545.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="RD508_003057"
     CDS             7732..8196
                     /locus_tag="RD508_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7737546.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="RD508_003058"
     CDS             8180..8809
                     /locus_tag="RD508_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDT7737547.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr(C)"
                     /locus_tag="RD508_003059"
     CDS             9163..10641
                     /gene="msr(C)"
                     /locus_tag="RD508_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HDT7737548.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="RD508_003060"
     CDS             10688..11134
                     /locus_tag="RD508_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HDT7737549.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="RD508_003061"
     CDS             complement(11333..11848)
                     /locus_tag="RD508_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7737550.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="RD508_003062"
     CDS             11965..13167
                     /locus_tag="RD508_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7737551.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4128 a         2432 c         2711 g         3975 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaacagccaa acaaaaatag cttctcatat ttttcg
//
LOCUS       DAPBCF010000201         7959 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.guided.089, whole genome shotgun sequence.
ACCESSION   DAPBCF010000201 DAPBCF010000000
VERSION     DAPBCF010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.guided.089"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            128..1564
                     /locus_tag="RD508_003063"
     CDS             128..1564
                     /locus_tag="RD508_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7737552.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="RD508_003064"
     CDS             1753..4200
                     /locus_tag="RD508_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDT7737553.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="RD508_003065"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="RD508_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDT7737554.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="RD508_003066"
     CDS             complement(5690..6793)
                     /locus_tag="RD508_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7737555.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="RD508_003067"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="RD508_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HDT7737556.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2664 a         1359 c         1729 g         2207 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacatat ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattactt
//
LOCUS       DAPBCF010000202         6156 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.guided.102, whole genome shotgun sequence.
ACCESSION   DAPBCF010000202 DAPBCF010000000
VERSION     DAPBCF010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.guided.102"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..185)
                     /locus_tag="RD508_003068"
     CDS             complement(<1..185)
                     /locus_tag="RD508_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7737557.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLG"
     gene            454..1350
                     /locus_tag="RD508_003069"
     CDS             454..1350
                     /locus_tag="RD508_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HDT7737558.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFNMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLAYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPIPSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1500..2441)
                     /locus_tag="RD508_003070"
     CDS             complement(1500..2441)
                     /locus_tag="RD508_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDT7737559.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFRSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKTAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYNPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2566..3687
                     /locus_tag="RD508_003071"
     CDS             2566..3687
                     /locus_tag="RD508_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDT7737560.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPHGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3945..5447
                     /gene="eat(A)"
                     /locus_tag="RD508_003072"
     CDS             3945..5447
                     /gene="eat(A)"
                     /locus_tag="RD508_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HDT7737561.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKSQPKHLSISYVRQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5514..6041
                     /locus_tag="RD508_003073"
     CDS             5514..6041
                     /locus_tag="RD508_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7737562.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
BASE COUNT         2022 a         1100 c         1264 g         1770 t
ORIGIN      
        1 cccagacctt tcatcacgat atataaaatc agcccgccaa tcaaaaaagc aatcaataca
       61 gaagggccgg cgatcccaat cgcttcgcca cttcctttaa atagacctgc accgattgct
      121 ccacctaaag ctaacatggt gatatgtctg gagctaagtt gttttttcaa ttttttatct
      181 tccataaatg acctctttct tttaaattca caatcaaaat ttatattaag aataaatagc
      241 aatatttaac aatgactaat gataacaaat tttcagacaa ttacaactat tcagaaaact
      301 tttaggcgaa ttttaataga agaatgattt atttcatcat attttcatac aaatgttaaa
      361 ttttcataca aatataggaa gcgttttact ggctttttac tatttaaaca ggctatcata
      421 ggaaaaagtg acagagaaag tgaggcggaa aagatgaaca aaaatgacgt actgctagtt
      481 gcaaaaaata aatcacttta ttttttgcct tccatccgct ctttagatgt ttggtccgga
      541 aaagatttac tacagtcgga attcattaaa tcagctagac aacagttggc aaattatcag
      601 ctgatcgttt ttttagatta tggatttaat atggagatgg ctcgacgcgt gcgcccattt
      661 accaatgcaa aaattgtgtt atttttttgg aatcacttca aagcagaaca cgaggcgatg
      721 ctgaagcagg cacaagatga accggcaatc gatgagattt atcattttga ttttttggaa
      781 gcaaaagaac ttgggctgaa acataatagt tcattttatt cgaaacatat ggatttttct
      841 tctagcgaac caaagacgga tctatttttt ggtgcaacga ataatgggag aaaagaacga
      901 gcagaaagct ataagcagga atttataaaa agagatgtta cgaccaacta tttcattctt
      961 ccacatcgag ggaatgaaca acctggatat cttgcttatg aagagtacct gaaaaaaaca
     1021 ggggaatcgc gcgggattct ggaactgttg cgggagggtc agcaaggagt gactttgcgg
     1081 acatttgaat ctatgtattt tcaaaagaaa ctagtgacgg ataatcaagc gattgctcat
     1141 tatcattttt atcgtcctga aaatattttt ttgcttcgag aacgtgattt agatgaatta
     1201 ccggaatttc tgcatacacc ttttaagcca atcccatcag agctattgga attttatgat
     1261 gcagaaaatt gggcaaaacg atttatcact aacgattcca ctatttatga gcaatacgaa
     1321 tatgacctct cctctgttga aaataaataa aaaacctaca ttttgaagag attatgtacc
     1381 gaaacaaaca agcacaattc ttatggcatc atgagagttg tgttttcttt ttgatctttc
     1441 attgggctta aaaaaagaga accagctgct gattcagctg attctcatca gagagccttt
     1501 tattctgcgc caaggattcc ttcttttgca tggactaatt gggtcaaaaa ggcacaatat
     1561 ggtgtagcaa tatcatattt ttgtcctttt cgccaaacgg caccattgat gtagtcgatt
     1621 tcagtcaaac gatggttttt gatcaggtct tggtacatag atgggtaatg caacccgatg
     1681 ttgtcaggat tataagtaga agcaatatgt tggtacactt cttcttgatc taatatgatt
     1741 ccttcttttg ctgcgataga agcaaattca gatacgattg ttcgaaccat gctctctgcc
     1801 gttttttgcg cgcctagttc agcaatatta caatccaaaa tcgtgcataa accattcaat
     1861 gttccattta cacaagcttt tcgccaaatg gaataacgaa cattatggct atagatcgga
     1921 tttaattttg cttcttgaaa gacttccaca actttttttg taaatgcttc gccttctggt
     1981 tccaagttct ctagttcgat ttctccatca cctaacaatg tgacttttcc gggaccagct
     2041 agaccagctg tccacatcgt gatcccaaat aagatatttt tctttggcac atatttttcc
     2101 agtacatctt catgacctaa tccatttagt aaacacaaaa cataagtatt gtcagtaata
     2161 atggattgga tcgaacgaaa catatcatct aattgattcg cttttgttaa tgctacgatc
     2221 aagtccacgt gttcgttgct ttcgatgatt tcttctggtg aatagattgg cagttttgcg
     2281 accacttctt taccgttaaa gtcagcaatc aacccatttg tacgaatggc ttcaatgtgt
     2341 gcaggccaac gatcgatcaa gaggacctca tttccgcttt gatgtagcat caatccgatt
     2401 cggctgccca ttgctccggc tccagctatt gcgattttca tgttttttct ctcctttatc
     2461 aatgagttcc cttttagtat atagaaaaat ggaagaaaat agcattgttt tgtttgaaaa
     2521 aaatgaaaaa aagtgtctta cttaagaaga aagtgaggga tacagatgga tattttggcg
     2581 gcaattgatt catttaaagg aagtgcttct tcatttgaac taaatcaggc agttctaaat
     2641 ggctgggaag atcgtaaagg aagaaaaatc aatgtgccga ttgcagatgg cggagaaaat
     2701 actgcagaag caatctatta cgcgctcggg ggaacatggc gtaccattga tgggatggat
     2761 cttttattcc gtcagcgaaa aatcagctat ttattgacaa cttggcaagg aaaaaatacc
     2821 gcagtcatcg aatctgcaca agcattgggg ttagatctac ttgataaacc aacggatcaa
     2881 actatccgac ttgcttccag ttatgcctta ggagaactta tcaaagatgc actgcttcaa
     2941 gaagtagaac aaattattgt cactttagga ggaagcgggt gtagcgatgg tggtctagga
     3001 ttactccaat ccttgggtgc ttctttagaa gggtacacag aaggaaatcc tttattatct
     3061 actaaaaaac ttcattttga tcgaagaaac gttcttgttt ctaaagtaaa attgattatc
     3121 gctgcagatg ttaccaatcc atatacaggt caacaaggag ctgcttggca atttggaaga
     3181 caaaaaggag gaatagatac gacgctagct ttcttagata aacaagcagg aaagattgct
     3241 cagcaaataa aagatttctg ggaggtggat ttagatgata ttccaggaag tggagcagca
     3301 ggcggtattg gtggagccct ttttttgttg ggagcgaaga tggtttctgg tttcgattta
     3361 gtcagccaaa tcactggatt ggaaaaaaag atcgaacaag cagatgtcat cattacagga
     3421 gaagggcgga tcgatcagca aacgatccac ggaaaagttc cacacggtgt agcagtgctt
     3481 gcaaaaaaat atcgaaaacc aataatcgct atttgcggaa gtagagacca agagctagaa
     3541 ggactctctg attttctccc aattgtctta agtattcatt tgggtccaat aggtttagaa
     3601 gaagcaatgg aacacaggca aacattagaa aaaacaaaaa tcttaggaca gacacttagc
     3661 agatttttca ccatcctccc gaagtagttg acaaaatcat tttctttatg ctatcgtaat
     3721 ttcaaatata ggacaaagtg agggatccgt gcattgaaaa attaagtcga ttgatgaaag
     3781 ctgcattcag actgtacctt gtggagacaa ggaagcagtg tgcagatttt cgggattggc
     3841 ttggtttttt cgatgtatgg gtctttttgt gtgtatccaa cccttgcatc ctctttagcc
     3901 agttctgaaa ataggactgg tcttttttta cgaggtgatg gaaaatgtct aaaatcgaaa
     3961 taaaaaatct gacattcggc tacgacagcc aaggcacatt attatttgaa caagcaaatc
     4021 taaattttga cacacaatgg aaactaggac ttatcggacg aaacggtcga ggaaagacaa
     4081 ctttactgaa tattctacaa aacaaactac cttatcaagg gcaagtaatc catcagcaag
     4141 aatttgccta tttcccgcaa cagacaaaag ataaagaacg tttaacctat tacgtgttaa
     4201 atgatattac ggattttgag atatgggaaa tcgaaagaga gctccaattg atgcaaacag
     4261 atcctgaaat cttatggaga gaattcagca cactatcggg gggagagaag acaaaagtcc
     4321 tactggcact tttatttgtg gatgacactc atttcccgtt aatcgatgaa ccaacgaatc
     4381 atttggatat ctctggtaga aaacaagtag cggcttattt gaaaaagaaa aaacaaggct
     4441 tcatcgtggt cagccatgac cggggattta tcgatgaagt agtggaccat gttttagcaa
     4501 tcgaaaaaag tcaactggaa ctttatcaag ggaatttctc tatctatgaa gaacagaaaa
     4561 aacttcgtga tgaatttgaa atggctcaaa atgaaaaatt gaaaaaagaa gtcagtaggc
     4621 taaagaaaac agcagctgaa aaagccgaat ggtctcgttc ccgagaagga gataaaacaa
     4681 agaaacaagt cggattcatc gatactgaat ctagacgagt gaataaagga gcagtgggtg
     4741 ctgatgctgc acggacgatg aaacgatcca aagcaatcgt gaatcggatg gagacccaga
     4801 tcagcgagaa agaaaaacta ttaaaagata tcgaatatat cgattctttg acgatgaata
     4861 gccaagcgtc tcaccataag cgacttttaa gcgtagaaga tcttcaatta gggtatgaaa
     4921 atctgttatt cgagccaatt cattttacaa tcgagcctca tcagcgggtg gcgatttcag
     4981 gtcctaacgg tgcaggaaag tcatccatta tccattatct tctgggggca ttcaacggca
     5041 aggttatagg agaaaaatcc cagccaaaac atctgagcat tagttatgta cgccaaaatt
     5101 atgaagacaa tcgaggaacg ttggcggaat ttgcagagaa aaaccaagta gactaccaag
     5161 catttttgaa caacctccga aagcttggga tggaaagaga tgtttttcat aacaagatcg
     5221 agcagatgag tatgggccaa cggaaaaaag tggaattggc taaatcttta tcacagccag
     5281 ctgaactata tacatgggat gaaccattga attatttgga tgtcttcaat caagaacaat
     5341 tagaacaact gatcttgaac gtgaaacctg ccatgttact agtggaacat gatcaaacct
     5401 tcctggataa agtatctact gagattattt ctcttgagag aatctaaccc ttgtaatctc
     5461 aagaacaaca aggtatggtt aaggggaaat ttgccaacga aggagagaat cacatgcttt
     5521 atgtaacgag acacggagaa acaacttgga acgcacaagg attagtttgc ggacgggcag
     5581 atgtgccgct gactgaaaaa ggacagatgc aggcacagaa actagcagaa aaggtagtag
     5641 atttgcctgt tccaatcacg aaaatcatcc attcccctct tcaacgagca agagatacag
     5701 cacaagcagt tgctgatcgt ctcagcttgc cgctgaccgt tgatgaacga ttggtagaaa
     5761 tggattttgg ggattatgat ggactgccaa gcaaagatga gaactttcaa aaagcacgtt
     5821 tagcgttcgc tgtacgattc ccaaatgggg agtcagtctt agatgtgtat gcacggatcg
     5881 ttcctttatt gaaagaatgc atcgaagacg aagaaaatgt ctatctgtta gtttgtcata
     5941 atgccttgat aagagtgatc aatgcttatt ttcatccgat gcctaatgag gggttcttta
     6001 cattcatggt agataataca gaattggttt cttatgagta attatgtttt tgtgttattt
     6061 aaataaaata tttcaaggca ctgcttttgc ttagcagtgc cttttttagg ttatgacaat
     6121 tcttttgata atataaactc aacctttaga aatgaa
//
LOCUS       DAPBCF010000203         4789 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.guided.119, whole genome shotgun sequence.
ACCESSION   DAPBCF010000203 DAPBCF010000000
VERSION     DAPBCF010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.guided.119"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            99..794
                     /gene="vanR"
                     /locus_tag="RD508_003074"
     CDS             99..794
                     /gene="vanR"
                     /locus_tag="RD508_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HDT7737563.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            772..1926
                     /locus_tag="RD508_003075"
     CDS             772..1926
                     /locus_tag="RD508_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HDT7737564.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2141..3109
                     /locus_tag="RD508_003076"
     CDS             2141..3109
                     /locus_tag="RD508_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HDT7737565.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3102..4133
                     /gene="vanA"
                     /locus_tag="RD508_003077"
     CDS             3102..4133
                     /gene="vanA"
                     /locus_tag="RD508_003077"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HDT7737566.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4139..4747
                     /locus_tag="RD508_003078"
     CDS             4139..4747
                     /locus_tag="RD508_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HDT7737567.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1479 a          916 c         1118 g         1276 t
ORIGIN      
        1 gggattttat tctttattta aaactttgca acagaaccaa ttcggcccta taatctgata
       61 aattattaag ggcaaactta tgtgaaaggg tgataactat gagcgataaa atacttattg
      121 tggatgatga acatgaaatt gccgatttgg ttgaattata cttaaaaaac gagaattata
      181 cggttttcaa atactatacc gccaaagaag cattggaatg tatagacaag tctgagattg
      241 accttgccat attggacatc atgcttcccg gcacaagcgg ccttactatc tgtcaaaaaa
      301 taagggacaa gcacacctat ccgattatca tgctgaccgg gaaagataca gaggtagata
      361 aaattacagg gttaacaatc ggcgcggatg attatataac gaagcccttt cgcccactgg
      421 agttaattgc tcgggtaaag gcccagttgc gccgatacaa aaaattcagt ggagtaaagg
      481 agcagaacga aaatgttatc gtccactccg gccttgtcat taatgttaac acccatgagt
      541 gttatctgaa cgagaagcag ttatccctta ctcccaccga gttttcaata ctgcgaatcc
      601 tctgtgaaaa caaggggaat gtggttagct ccgagctgct atttcatgag atatggggcg
      661 acgaatattt cagcaagagc aacaacacca tcaccgtgca tatccggcat ttgcgcgaaa
      721 aaatgaacga caccattgat aatccgaaat atataaaaac ggtatggggg gttggttata
      781 aaattgaaaa ataaaaaaaa cgactattcc aaactagaac gaaaacttta catgtatatc
      841 gttgcaattg ttgtggtagc aattgtattc gtgttgtata ttcgttcaat gatccgaggg
      901 aaacttgggg attggatctt aagtattttg gaaaacaaat atgacttaaa tcacctggac
      961 gcgatgaaat tatatcaata ttccatacgg aacaatatag atatctttat ttatgtggcg
     1021 attgtcatta gtattcttat tctatgtcgc gtcatgcttt caaaattcgc aaaatacttt
     1081 gacgagataa ataccggcat tgatgtactt attcagaacg aagataaaca aattgagctt
     1141 tctgcggaaa tggatgttat ggaacaaaag ctcaacacat taaaacggac tctggaaaag
     1201 cgagagcagg atgcaaagct ggccgaacaa agaaaaaatg acgttgttat gtacttggcg
     1261 cacgatatta aaacgcccct tacatccatt atcggttatt tgagcctgct tgacgaggct
     1321 ccagacatgc cggtagatca aaaggcaaag tatgtgcata tcacgttgga caaagcgtat
     1381 cgactcgaac agctaatcga cgagtttttt gagattacac ggtataacct acaaacgata
     1441 acgctaacaa aaacgcacat agacctatac tatatgctgg tgcagatgac cgatgaattt
     1501 tatcctcagc tttccgcaca tggaaaacag gcggttattc acgcccccga ggatctgacc
     1561 gtgtccggcg accctgataa actcgcgaga gtctttaaca acattttgaa aaacgccgct
     1621 gcatacagtg aggataacag catcattgac attaccgcgg gcctctccgg ggatgtggtg
     1681 tcaatcgaat tcaagaacac tggaagcatc ccaaaagata agctagctgc catatttgaa
     1741 aagttctata ggctggacaa tgctcgttct tccgatacgg gtggcgcggg acttggattg
     1801 gcgattgcaa aagaaattat tgttcagcat ggagggcaga tttacgcgga aagcaatgat
     1861 aactatacga cgtttagggt agagcttcca gcgatgccag acttggttga taaaaggagg
     1921 tcctaagaga tgtatataat tttttaggaa aatctcaagg ttatctttac tttttcttag
     1981 gaaattaaca atttaatatt aagaaacggc tcgttcttac acggtagact taataccgta
     2041 agaacgagcc gttttcgttc ttcagagaaa gatttgacaa gattaccatt ggcatccccg
     2101 ttttatttgg tgcctttcac agaaagggtt ggtcttaatt atgaataaca tcggcattac
     2161 tgtttatgga tgtgagcagg atgaggcaga tgcattccat gctctttcgc ctcgctttgg
     2221 cgttatggca acgataatta acgccaacgt gtcggaatcc aacgccaaat ccgcgccttt
     2281 caatcaatgt atcagtgtgg gacataaatc agagatttcc gcctctattc ttcttgcgct
     2341 gaagagagcc ggtgtgaaat atatttctac ccgaagcatc ggctgcaatc atatagatac
     2401 aactgctgct aagagaatgg gcatcactgt cgacaatgtg gcgtactcgc cggatagcgt
     2461 tgccgattat actatgatgc taattcttat ggcagtacgc aacgtaaaat cgattgtgcg
     2521 ctctgtggaa aaacatgatt tcaggttgga cagcgaccgt ggcaaggtac tcagcgacat
     2581 gacagttggt gtggtgggaa cgggccagat aggcaaagcg gttattgagc ggctgcgagg
     2641 atttggatgt aaagtgttgg cttatagtcg cagccgaagt atagaggtaa actatgtacc
     2701 gtttgatgag ttgctgcaaa atagcgatat cgttacgctt catgtgccgc tcaatacgga
     2761 tacgcactat attatcagcc acgaacaaat acagagaatg aagcaaggag catttcttat
     2821 caatactggg cgcggtccac ttgtagatac ctatgagttg gttaaagcat tagaaaacgg
     2881 gaaactgggc ggtgccgcat tggatgtatt ggaaggagag gaagagtttt tctactctga
     2941 ttgcacccaa aaaccaattg ataatcaatt tttacttaaa cttcaaagaa tgcctaacgt
     3001 gataatcaca ccgcatacgg cctattatac cgagcaagcg ttgcgtgata ccgttgaaaa
     3061 aaccattaaa aactgtttgg attttgaaag gagacaggag catgaataga ataaaagttg
     3121 caatactgtt tgggggttgc tcagaggagc atgacgtatc ggtaaaatct gcaatagaga
     3181 tagccgctaa cattaataaa gaaaaatacg agccgttata cattggaatt acgaaatctg
     3241 gtgtatggaa aatgtgcgaa aaaccttgcg cggaatggga aaacgacaat tgctattcag
     3301 ctgtactctc gccggataaa aaaatgcacg gattacttgt taaaaagaac catgaatatg
     3361 aaatcaacca tgttgatgta gcattttcag ctttgcatgg caagtcaggt gaagatggat
     3421 ccatacaagg tctgtttgaa ttgtccggta tcccttttgt aggctgcgat attcaaagct
     3481 cagcaatttg tatggacaaa tcgttgacat acatcgttgc gaaaaatgct gggatagcta
     3541 ctcccgcctt ttgggttatt aataaagatg ataggccggt ggcagctacg tttacctatc
     3601 ctgtttttgt taagccggcg cgttcaggct catccttcgg tgtgaaaaaa gtcaatagcg
     3661 cggacgaatt ggactacgca attgaatcgg caagacaata tgacagcaaa atcttaattg
     3721 agcaggctgt ttcgggctgt gaggtcggtt gtgcggtatt gggaaacagt gccgcgttag
     3781 ttgttggcga ggtggaccaa atcaggctgc agtacggaat ctttcgtatt catcaggaag
     3841 tcgagccgga aaaaggctct gaaaacgcag ttataaccgt tcccgcagac ctttcagcag
     3901 aggagcgagg acggatacag gaaacggcaa aaaaaatata taaagcgctc ggctgtagag
     3961 gtctagcccg tgtggatatg tttttacaag ataacggccg cattgtactg aacgaagtca
     4021 atactctgcc cggtttcacg tcatacagtc gttatccccg tatgatggcc gctgcaggta
     4081 ttgcacttcc cgaactgatt gaccgcttga tcgtattagc gttaaagggg tgataagcat
     4141 ggaaatagga tttacttttt tagatgaaat agtacacggt gttcgttggg acgctaaata
     4201 tgccacttgg gataatttca ccggaaaacc ggttgacggt tatgaagtaa atcgcattgt
     4261 agggacatac gagttggctg aatcgctttt gaaggcaaaa gaactggctg ctacccaagg
     4321 gtacggattg cttctatggg acggttaccg tcctaagcgt gctgtaaact gttttatgca
     4381 atgggctgca cagccggaaa ataacctgac aaaggaaagt tattatccca atattgaccg
     4441 aactgagatg atttcaaaag gatacgtggc ttcaaaatca agccatagcc gcggcagtgc
     4501 cattgatctt acgctttatc gattagacac gggtgagctt gtaccaatgg ggagccgatt
     4561 tgattttatg gatgaacgct ctcatcatgc ggcaaatgga atatcatgca atgaagcgca
     4621 aaatcgcaga cgtttgcgct ccatcatgga aaacagtggg tttgaagcat atagcctcga
     4681 atggtggcac tatgtattaa gagacgaacc ataccccaat agctattttg atttccccgt
     4741 taaataaact ttggttctgt tgcaaagttt taaataaaga ataaaatcc
//
LOCUS       DAPBCF010000204         3970 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.guided.131, whole genome shotgun sequence.
ACCESSION   DAPBCF010000204 DAPBCF010000000
VERSION     DAPBCF010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.guided.131"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="RD508_003079"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="RD508_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HDT7737568.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="RD508_003080"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="RD508_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HDT7737569.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT         1254 a          613 c          818 g         1285 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcaggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaggaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc
     3841 ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata gtgtgttata
     3901 ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg ccacctaaaa
     3961 aggagcgatt
//
LOCUS       DAPBCF010000205         3970 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.guided.132, whole genome shotgun sequence.
ACCESSION   DAPBCF010000205 DAPBCF010000000
VERSION     DAPBCF010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.guided.132"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="RD508_003081"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="RD508_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HDT7737570.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="RD508_003082"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="RD508_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HDT7737571.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT         1253 a          613 c          819 g         1285 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcgggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaggaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc
     3841 ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata gtgtgttata
     3901 ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg ccacctaaaa
     3961 aggagcgatt
//
LOCUS       DAPBCF010000206         3687 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.guided.134, whole genome shotgun sequence.
ACCESSION   DAPBCF010000206 DAPBCF010000000
VERSION     DAPBCF010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.guided.134"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..152
                     /locus_tag="RD508_003083"
     CDS             <1..152
                     /locus_tag="RD508_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737572.1"
                     /translation="VLDKYNVQGKERTVMLAKDSEGLNKLGFSSQLVEGALSGAHSQR
                     CHAPI"
     gene            488..1135
                     /locus_tag="RD508_003084"
     CDS             488..1135
                     /locus_tag="RD508_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-8 chloramphenicol O-acetyltransferase"
                     /protein_id="HDT7737573.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKEFDITLLKSMIKN
                     KGYELYPALIYTIVNIINQNKVFRTGINSEGNLGYWEKLNPLYTVFNKETEKFSNIWT
                     ESNVSFNSFYNSYKSDLLEYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNS
                     RFLLPIITIGKFYSKNNKIYLPVSLQVHHAVCDGYHVSLFMSEFQNIVDSVNEWI"
     gene            1388..2599
                     /locus_tag="RD508_003085"
     CDS             1388..2599
                     /locus_tag="RD508_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003672456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HDT7737574.1"
                     /translation="MSFAVARMQKVKSGNLVGVGNHNQRNTDNHSNKDIDVERSHLNY
                     DLVNRTENYKRDIEQFINDNKSSSRAVRKDAVLINEWIITSDNPFFKDKDDKEIKDFF
                     DTAKSYFADKFGDNNIRYAQVHLDETTPHMHLGIVPFNDEHKLSAKTVFNRQALQAVQ
                     DELPKYLNERGFELERGEKGSERKNLTVPEYKKAKDELKEITTTLEQRKSEVLALSND
                     KAPTIKKESLDLKDETKTVKVPSGETIGIGKLRHEFMKNEERKTGNVIIPESKLNAVI
                     KSYEELYKANEKLKNYAETDLPKEITRVKEKYRELAKDYNRLVRKSNQNIETLEELEK
                     ENKSLKNEIKGIYKGFNQFMENTLGATVGQAKKLMNNLMSEVKEFVKGGEFEKIHRNE
                     TKTRDRDELSR"
     gene            3143..3298
                     /locus_tag="RD508_003086"
     CDS             3143..3298
                     /locus_tag="RD508_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein repA"
                     /protein_id="HDT7737575.1"
                     /translation="MVEVEKKKVTLSLPVESNDKLEKMAQKYGMTKSGLVTFLINQAD
                     DKGTIFK"
     gene            3422..>3687
                     /locus_tag="RD508_003087"
     CDS             3422..>3687
                     /locus_tag="RD508_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepB"
                     /protein_id="HDT7737576.1"
                     /translation="MENENRTDWTLPRKNLNPKTKQPYKRGRNWWIVVYPESLPENWK
                     EIISTEPVAISPLHDKDVNADGTKKKPHYHIVFNRIRQKSPILY"
BASE COUNT         1373 a          474 c          721 g         1119 t
ORIGIN      
        1 gtgtcttgga taaatacaat gtacaaggta aagaaagaac tgtgatgttg gcaaaagata
       61 gcgaaggttt gaataaacta gggttttcga gtcagttagt tgaaggagct ttatctggtg
      121 ctcacagtca aagatgtcat gcaccaatat aaaaatattt ccatattcct ctactttatt
      181 tatgtagagg gatattattg tgctaatagc attgttaagt caatcaatta tacttaaata
      241 gtctgattta tttgcaaagt tgaagtttaa tgaaatcgac tttaaaagcg aacgaaaaac
      301 aattgcaaaa gcagattgat ttttggcaac gtgaatttag attttggaag taaagtaact
      361 ttgttttata caaaatgtta ctttagtata attaacgttt aagaggtgac acaatatatg
      421 aaaaaatcag aggattattc ctcctaaata caaagagata agatgaaatt taggaggaaa
      481 attatatatg acttttaata ttattaattt ggaaacttgg gatagaaaag aatattttaa
      541 tcattatttc aatcaacaaa caacttacag tgttactaaa gaatttgata tcactttact
      601 taaaagtatg ataaaaaata aaggatatga actgtatcct gctttgattt atacaattgt
      661 aaatattata aatcaaaata aagtatttag aacaggaatt aatagtgagg gaaatttggg
      721 ttattgggaa aaattaaacc ctttatatac agtctttaat aaagaaactg aaaaattttc
      781 taacatttgg acagaatcaa atgttagttt taattctttt tataatagtt ataagagtga
      841 cttacttgaa tataaagata aaaatgaaat gtttcctaaa aaaccaatac ctgaaaacac
      901 agttcctatt tcgatgattc cttggattga ttttagttca tttaatttaa atattggtaa
      961 taatagtaga ttcctattgc caattattac aataggtaaa ttttatagta agaataataa
     1021 gatctattta ccagtctcat tgcaagttca tcatgcggta tgtgatggtt accatgtttc
     1081 attatttatg agtgaatttc aaaatatagt tgatagtgta aatgaatgga tttaaatcta
     1141 aaataacttt cataaactta agtaattatg atatttataa gtttatagca actaccattt
     1201 ttggttgctg gtgttttgat tttgaatttg gttttgaact tatggactga tttattcagt
     1261 ccattttttg tgcttgcaca aaaactagcc tcgcagagca cacgcattaa tgacttatga
     1321 aacgtagtaa ataagtctag tgggttatac tttacatgga agttgtgccg aagttaggag
     1381 tgtttacatg tcatttgcag tggcgagaat gcagaaggta aaatcaggaa atttagtcgg
     1441 ggtaggtaat cataatcaga gaaatacaga caatcattcc aacaaagata ttgatgttga
     1501 acggtcgcat ttaaattatg atttggtcaa tcggacagaa aattataaac gagatattga
     1561 gcaatttatt aacgacaata aatcaagtag tcgtgctgtc agaaaagatg ctgtattaat
     1621 aaacgaatgg atcataactt ctgacaaccc attttttaaa gataaagacg ataaagaaat
     1681 taaagatttt tttgatactg cgaaatcata ttttgcggac aaatttggcg ataataatat
     1741 ccgctacgct caagttcact tagacgaaac gacaccgcat atgcacttag gaattgtgcc
     1801 gtttaatgac gaacacaagc tatcagcaaa gactgttttt aatcgtcaag ccttacaagc
     1861 ggtacaagac gaattgccaa agtatttaaa tgagcgtggt tttgagcttg aacgtggcga
     1921 aaaagggtca gagcgtaaaa atttaacggt gcctgaatat aaaaaggcaa aggacgaatt
     1981 aaaagagata actaccacgc tggaacagcg aaagtcagaa gttttagcgt tatcgaacga
     2041 taaagcacca acaatcaaga aagaaagttt agatttaaaa gacgaaacga aaacggtcaa
     2101 agtaccaagt ggcgaaacca ttgggattgg taagctgcga catgaattta tgaaaaatga
     2161 agaacgaaaa acgggaaatg taattatccc tgaaagtaaa ttaaatgcag tgattaaaag
     2221 ctatgaagag ctatataaag caaatgaaaa gctaaaaaat tatgcggaaa ctgatttacc
     2281 taaagaaatc actagagtta aagagaaata tcgcgaatta gcgaaagatt acaataggtt
     2341 ggtacgtaag agtaatcaga atattgaaac acttgaagaa ttagagaaag agaataagtc
     2401 gcttaaaaac gaaattaagg gcatttacaa aggttttaac cagtttatgg aaaataccct
     2461 tggtgcaact gttggacaag ctaaaaagct gatgaataac cttatgagcg aagttaaaga
     2521 gtttgtaaaa ggtggagagt ttgaaaaaat tcatagaaac gaaactaaaa cacgagatag
     2581 ggatgaatta agtcgttaga agctcatatt tgcgttctaa gcgctttttt atcaaaacta
     2641 gggtaattct gcatattgtt tacttttcgt cggcaaatgc gtaaaaaaca gcgaaataaa
     2701 agaggtcaag ggcgaacgta gtgagtgtat ttacccttga tctctttttt tgagttgttt
     2761 agcttttgct aagacgacgg aaagaaacga atgcagttat caagttgctt ttcagaggca
     2821 aggtcaagcg ctttgcgctt gttgggtgtg ggcgaatagc ccacggtttt attatttgga
     2881 aatttagtgg gagcaggggg cgaaaaaaca tgggaatttt tggagcgaaa aaacatgggg
     2941 gcactacgac accccccatg tgtccattgt ccattgtcca aatagataaa aagattaaat
     3001 gtcttgtaaa tacctttata tgaacgtttt aagcacctat ttcgaggtga aaaaaagttt
     3061 tttgtaaaat cttgtattcc tgtcgtatgt ataatataat tacagtgtaa aagagatttt
     3121 gaagagaatt gaggtgcatt ttgtggttga agttgagaag aaaaaagtga ctttatcttt
     3181 acctgttgaa tcgaatgaca aactagaaaa aatggcacaa aaatatggaa tgactaaatc
     3241 aggtttggtt acatttttaa ttaatcaagc tgatgataag gggactattt ttaaataaaa
     3301 aaagccctgc taggaagata gcaagggctc gcaagatttg gttttctttg atttcgcaac
     3361 tcaagtttat caaattttcc cttgttttcc tagtagagta actaggaagg tgtagaaaaa
     3421 tatggaaaat gaaaatagaa cagattggac attgcctaga aagaatttaa atccaaaaac
     3481 taaacagcct tataagcgag gtcgtaactg gtggattgtt gtttatcctg aaagtttgcc
     3541 agagaattgg aaagagatta tttcaactga acctgtggca attagtccat tacatgataa
     3601 agatgttaat gcagacggaa caaagaaaaa gccgcattat catatagttt ttaacagaat
     3661 taggcagaag tcgcccatcc tctatag
//
LOCUS       DAPBCF010000207         2889 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.guided.140, whole genome shotgun sequence.
ACCESSION   DAPBCF010000207 DAPBCF010000000
VERSION     DAPBCF010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2889
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.guided.140"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..676)
                     /locus_tag="RD508_003088"
     CDS             complement(<1..676)
                     /locus_tag="RD508_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737577.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKYVF
                     EKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEI
                     NRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELI
                     FSLTTPG"
     gene            complement(1391..1681)
                     /locus_tag="RD508_003089"
     CDS             complement(1391..1681)
                     /locus_tag="RD508_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737578.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1889..2092)
                     /locus_tag="RD508_003090"
     CDS             complement(1889..2092)
                     /locus_tag="RD508_003090"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7737579.1"
                     /translation="MNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLE
                     KAKDEVEDTADKSQQIVEEHLRK"
     gene            complement(2189..2581)
                     /locus_tag="RD508_003091"
     CDS             complement(2189..2581)
                     /locus_tag="RD508_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HDT7737580.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEIN"
BASE COUNT          885 a          524 c          399 g         1081 t
ORIGIN      
        1 tccctggagt tgtcaaagag aaaattaatt ctgctaagct tattattgaa aatactgata
       61 acttataatt atatcgtcca ttgacaatca aatataaact aactatactt gttagaacaa
      121 aaaaacaggc gttgacttgt tcttgattag ttaaaaatat caataaagga atacttaccc
      181 aatatatttt tctatttatt tcttctcctc ttaagagttg aaaaaacgga taaaaagtta
      241 gtaaactaaa tgctactggc cactgatagt tcaaggtggt tgctctccaa ccggtttccc
      301 ccattactgt caatggtatt aaacagtata tagagcaaac caataataaa tttttaacat
      361 ttattttctc aaaaacatac ttgcaaagta atactacaat tcctaacata atcgtagaat
      421 ttaataattt ccatagcata aagtgtttag aaaagaacat taagaatagt tctataataa
      481 ttcttgaact ccatgtctta taatgttcta tcgaagcacc caaatagcca agttcatcta
      541 atctacttgc ataaactacg tcatccgctc tcatagtcgg catatacata ttaaagagta
      601 aaaagatacc ccaaatccct attagtaaca agatcagttc tttgttattc gttatttttc
      661 tattatgttt gttcattttt atactccttc ttatatttcc taatagagta taacatagct
      721 ttaagcatta cttaaagata acttaaaagt tatcttttaa atacttaatt gttaaatacc
      781 ttatttgatg caaaagaaat ctacgatagt caacaaaaaa aattttcatt atatccagaa
      841 aaatttttct tagttaagga cctatggatt gcagtaatgc agaattcgtc gaataaactg
      901 ccaaagacat acaatcatat tgcttttaaa attgacgaac aagatataga ttcgtttgtc
      961 tcaaaaatcc aaatgttagg tttaactgtc gaaccaggac gttctcgtgt gaaagacgag
     1021 gcttcttcaa tttactttta cgactatgat aatcacctct tcgagttaca taccggtact
     1081 ctccaggaac gtttaaaatc ctacaattcc actacctgag actagtaatg actagtctct
     1141 ttttatggcc tctgatcccc ccattgagcg aatactaata gggcttcgaa ttgatctgtt
     1201 caatctttaa gcaatatccc tcaaatgagt ttggaaagtt tagtgattca tcacaaatac
     1261 ttaaatacat gtagttatat atagattgag gttcttgtga gcgtatgctc gtgtgggttc
     1321 aaatcccatc gtctgaatcc atctttccaa aacaagcggc taggacattt ttgtctcagc
     1381 cgcttgtttt ctagtttatt ctttcatctt gtcggacctt ttttcttggg tatagacttt
     1441 tctcatattc taccacaatt ttgggtttcc ctaacacatg ataggatctc acaacaaatt
     1501 gctttctatt attataataa cctgtaacga ctaacttcat cccttcgtct acttcagcta
     1561 ggaagttcaa actatgggaa gcaatcaaac aattgacccc atttaaactg aaacggatca
     1621 acggtctggc actaacttgc aaagtacgga tcttatctac tgttccatat tttttctcca
     1681 taaccttcac ctcaatacca ttatacgaac atacattccc tttgtaaaga agaaactctg
     1741 ttttatcttt ttgacttttt gtctattacc tttcttaaaa tcatattggc acttcctgcg
     1801 aagatgaagg acatgtacta aaaaaaagag gcagcagtat agattactgt tgcttcttta
     1861 ctaatttagg tttacttgtt aagaaagatt atttacgcaa atgttcttca acaatttgct
     1921 gagatttatc agctgtatct tccacttcat cttttgcttt ttctaacttt tgaatatatt
     1981 gtttcaagct tgagttttca gcagttgctt cgtctaattt cttttgtgta tctgttaact
     2041 gagtttctac atttgttttt tcttgtgtca gtgttgcgat ttgttgattc aaaccattta
     2101 cagtattttg taattctgaa agttttgctt gtgcttcttg tagtcttgct gtccaatctg
     2161 cattcagatg attgatttca tcattttttt agttgatctc atctagtttg acattgattt
     2221 cattttgctt gctttgtagt tgtgcatcct tgctgactaa ttgactttct aagttttgtt
     2281 tttctgctgc cgattgattt ttttggtttt ctaattcatt tacttttgtt tggtattctt
     2341 ggacatctgc ctttgaatct tgcaatgtct gttctttttg tgctagtcga gcggtaagat
     2401 ctgtaatcgc ttgctcttta tctgtcaatg tatgatcaag ctgtgtcaga ttctcattga
     2461 ttgtatcaat atctgtctct ccaccccaca aaataatttc atttgcgtac cgcgtgcctg
     2521 tgtagccaat tagacataga aatgcaacga caatcccacc agtaataaat ttctttttca
     2581 tttgcatagc tccttaatcc aatactttta catactaaaa gtaagtgatc tcaaacacaa
     2641 tgtcaagcgt ttttaaatta catatgtaat tttaatataa atactatcaa atactcattt
     2701 aatcctcctt ttttatctat ttaaaaaatc ttttttatag agaaaaatgc aggttaatac
     2761 tttcttaaat aaatatttat ggtgaacaaa aacaaaaaag caagttttat taaacgtaac
     2821 ccttttcatt tcatagatta ctgtatttat tacaaaaaac gtggatttgt cataaattgt
     2881 catgcttct
//
LOCUS       DAPBCF010000208         1032 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-033
            SAMN36683423-rid18909613.guided.178, whole genome shotgun sequence.
ACCESSION   DAPBCF010000208 DAPBCF010000000
VERSION     DAPBCF010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683423
            Sequence Read Archive: SRR25390885
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831654.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831654.1
            Genome Coverage       :: 107x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:02:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,942
            CDSs (with protein)               :: 2,942
            Genes (RNA)                       :: 67
            rRNAs                             :: 4, 2 (16S, 23S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 39 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683423-rid18909613.guided.178"
                     /isolate="VREC-033"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            87..146
                     /gene="ermCL"
                     /locus_tag="RD508_003092"
     CDS             87..146
                     /gene="ermCL"
                     /locus_tag="RD508_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methylase leader peptide ErmCL"
                     /protein_id="HDT7737581.1"
                     /translation="MGIFSIFVINTVHYQPNKK"
     gene            194..928
                     /locus_tag="RD508_003093"
     CDS             194..928
                     /locus_tag="RD508_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(T)"
                     /protein_id="HDT7737582.1"
                     /translation="MNKKNIKDSQNFITSKHHINEILRNVHLNTNDNIIEIGSGKGHF
                     TFELAKRCNYVTAIEIDPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIYGNI
                     PYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPR
                     EYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKY
                     ARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          415 a          136 c          140 g          341 t
ORIGIN      
        1 agggatttta ttctttattt aaaactttgc aacagaacca gcttgtgcta taattattct
       61 aatttcataa aaaggagaat taatatatgg gcatttttag tatttttgta atcaacacag
      121 ttcattatca accaaacaaa aaataagtgg ttataatgga ttgttaatat aaacctcata
      181 ggagtgggtt ataatgaaca aaaaaaatat aaaagatagt caaaacttta ttacttcaaa
      241 gcatcatata aatgaaattt tgagaaatgt acatttaaat acaaatgata atattattga
      301 gattggttca gggaaaggtc atttcacgtt tgaattagct aaaaggtgta attatgtaac
      361 cgccattgaa atagatccta aattatgtag gataactaaa aacaaactta ttgaatatga
      421 gaacttccag gttatcaata aagatatttt acaatttaag tttcctaaaa ataagtcata
      481 taagatatat ggaaatatac cctacaatat aagtacagat ataattcgaa aaattgtttt
      541 tgaaagcaca gctacagaaa gttatttaat agtggaatat ggatttgcta aaaggttgct
      601 aaatacaaat cgttcactag cactattttt aatgacagaa gttgatatat ccatattaag
      661 taaaatccct agagaatact ttcatccaaa acctagagtt aatagctcgt taattgtatt
      721 aaaaagacac ccttcaaaaa tatcactcaa agatagaaaa caatatgaaa attttgttat
      781 gaaatgggtt aacaaagaat acataaaact attttccaaa aaccaatttt atcaagcctt
      841 aaaatatgca agaattgacg atttaaacaa tattagcttt gaacaattct tgtctctttt
      901 caatagctat aaattattta atagataagt taaggggtgc ataaactgca tcccttaact
      961 tatcttattt tgcttaaaca atcttggccc gtaaactgca taactcatat gtaaatcgct
     1021 cctttttagg tg
//
